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{"sheet":"Sheet 1","index":0,"n_rows":579,"n_cols":11,"rows_kept":579,"merged":[[0,0,0,10],[546,0,546,10]],"flags":["formulas_cached_only"]}
["Enrichment analysis of genes in grey module"]
["ONTOLOGY","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count","zscore"]
["BP","GO:0008202","steroid metabolic process","44/463","331/18670",6.61735593522476e-20,2.70914551988102e-16,2.29099828115308e-16,"APOA4/AGT/FASN/G6PC/CYP3A5/CYP3A7/CYP2D6/FGF19/SCARB1/ACADVL/CYP17A1/CYP1B1/HMGCS1/EGR1/DHRS2/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/RXRA/HSD17B2/COMT/LIPC/LSS/HSD17B11/FDFT1/PPARGC1A/UGT2B17/UGT2B11/NR0B2/NPC1L1/HMGCR/ACAT2/ELOVL6/HSD17B14/ERG28/SMPD1/AGTR1/NR1D1/MVK/NR1H4/SOAT2/SERPINA12",44,-1.50755672288882]
["BP","GO:0019216","regulation of lipid metabolic process","39/463","410/18670",6.6625751152477e-13,4.54609708697068e-10,3.84442272878065e-10,"APOA4/AGT/FASN/PLIN2/FGF19/SCARB1/ACADVL/CPT1A/HMGCS1/G0S2/EGR1/DHCR7/EEF1A2/SREBF1/ANGPTL8/DGAT2/ANGPTL4/CYP7A1/IDI1/RXRA/LSS/FDFT1/FGF21/PPARGC1A/RDH10/HMGCR/UGT1A9/PNPLA2/TNFRSF1A/ELOVL6/CEACAM1/PLIN5/CISH/AGTR1/NR1D1/MVK/NR1H4/ENHO/SERPINA12",39,-0.800640769025436]
["BP","GO:0006066","alcohol metabolic process","36/463","364/18670",1.6981162129501e-12,9.93155396545386e-10,8.39865296901184e-10,"APOA4/FASN/CYP2D6/SCARB1/ACADVL/CYP1B1/TKFC/HMGCS1/DHCR7/SREBF1/DGAT2/CYP7A1/ALDH1B1/IDI1/RXRA/ACSS2/LIPC/AKR1A1/LSS/FDFT1/NR0B2/RDH10/RDH11/NPC1L1/HMGCR/ITPK1/ACAT2/ELOVL6/ERG28/GK/SMPD1/MVK/NR1H4/PLCH2/SOAT2/SERPINA12",36,-1]
["BP","GO:0044282","small molecule catabolic process","35/463","445/18670",1.91369402094855e-09,5.59618808697385e-07,4.73243581571413e-07,"SCARB1/ACADVL/OAT/TKFC/CPT1A/CYP7A1/LRP5/ALDH1B1/HADHA/AKR1A1/SHMT2/HADHB/GUSB/ENO3/ALDOC/GCK/GCAT/ACAT2/KYNU/NT5E/PRODH/GALM/GALT/PLIN5/GK/NPL/ESD/UPP2/PGM2/NUDT16/CROT/BCKDK/SLC27A4/ECHDC1/XYLB",35,-3.54964786985977]
["BP","GO:0062012","regulation of small molecule metabolic process","32/463","459/18670",1.60567662509603e-07,2.52832311659351e-05,2.13808519025945e-05,"APOA4/FASN/FGF19/IGFBP3/ACADVL/CPT1A/HMGCS1/EGR1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/COMT/SHMT2/LSS/FDFT1/PPARGC1A/AK4/PPIF/RDH10/GCK/HMGCR/ELOVL6/CEACAM1/PLIN5/NR1D1/MVK/PID1/NR1H4/SLC25A33/SERPINA12",32,-0.707106781186547]
["BP","GO:0006631","fatty acid metabolic process","30/463","383/18670",3.105800971286e-08,6.05483294116422e-06,5.12029042333816e-06,"APOA4/FASN/ACSL4/CYP2D6/ACADVL/CYP2A7/CYP1B1/CPT1A/SREBF1/DGAT2/CYP7A1/HPGD/HADHA/ACSS2/LIPC/HADHB/PPARGC1A/ACSM1/TNFRSF1A/ACAT2/ELOVL6/CEACAM1/ACSF2/CYGB/PLIN5/CROT/SLC27A4/ALOX15B/CYP2D7/ECHDC1",30,-2.19089023002066]
["BP","GO:0006979","response to oxidative stress","29/463","451/18670",3.12908374872582e-06,0.00027256316738901,0.000230493985432457,"APOA4/SOD2/LCN2/SDC1/TXNIP/CYP1B1/FOS/VNN1/DHRS2/HSPA1A/HMOX1/HSPA1B/JUN/MET/SIGMAR1/SOD3/PPARGC1A/PPIF/AIFM1/BNIP3/HBB/FBXO7/PRODH/CYGB/STC2/CHRNA4/HGF/SGK2/C19orf12",29,-1.29986736723936]
["BP","GO:0031667","response to nutrient levels","29/463","499/18670",2.14275030612674e-05,0.00112466919913883,0.000951080399035203,"REG1A/IGFBP2/G6PC/LCN2/ACSL4/CCND1/HMGCS1/SREBF1/HMOX1/JUN/CDKN1A/SLC39A5/COMT/BCHE/FGF21/SST/PPARGC1A/AIFM1/HMGCR/AQP3/ATF3/BAIAP2/KYNU/PIM1/ABCG5/STC2/FES/NR1H4/SLC27A4",29,-2.78543007265578]
["BP","GO:0015711","organic anion transport","28/463","482/18670",2.99227597146565e-05,0.00147594913580486,0.00124814149272676,"APOA4/AGT/PLA2G2A/G6PC/ACSL4/PLIN2/SLC22A7/SCARB1/CPT1A/RXRA/SLC37A4/HBB/SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/SLC25A4/NR1H4/CROT/SLC6A11/SLC27A4/CPTP/SLC44A4/SLC16A13/SLC16A9",28,-1.51185789203691]
["BP","GO:0010876","lipid localization","27/463","400/18670",2.79150763797453e-06,0.000248444179779733,0.000210097680121241,"CRP/APOA4/AGT/PLA2G2A/LBP/ACSL4/PLIN2/SERPINA5/SCARB1/CPT1A/SYT7/DGAT2/RXRA/LIPC/SIGMAR1/NPC1L1/PNPLA2/SLC22A9/CEACAM1/PLIN5/ABCG5/AGTR1/NR1H4/CROT/SLC27A4/CPTP/SOAT2",27,-2.50185116648838]
["BP","GO:0006732","coenzyme metabolic process","27/463","403/18670",3.2106597451476e-06,0.000273842520763214,0.000231575875039264,"FASN/ACSL4/HMGCS1/VNN1/IDH2/DGAT2/H6PD/ACSS2/AKR1A1/SHMT2/ENO3/PPARGC1A/ACSM1/ALDOC/GCK/HMGCR/SUCLG1/ELOVL6/KYNU/NT5E/ACSF2/BTD/KCNAB2/PGM2/NADK/MVK/CROT",27,-2.11695098702863]
["BP","GO:0046394","carboxylic acid biosynthetic process","27/463","462/18670",3.73780443515285e-05,0.00171939004017031,0.00145400813568512,"APOA4/FASN/CYP2D6/FGF19/ACADVL/SEPHS2/OAT/CYP7A1/HPGD/ACSS2/LIPC/AKR1A1/SHMT2/PHGDH/PSAT1/ENO3/PPARGC1A/ACSM1/ALDOC/RDH10/GCK/ELOVL6/KYNU/CEACAM1/NR1D1/NR1H4/ALOX15B",27,-1.73205080756888]
["BP","GO:0016053","organic acid biosynthetic process","27/463","463/18670",3.87949297765151e-05,0.00174534552203355,0.00147595747871554,"APOA4/FASN/CYP2D6/FGF19/ACADVL/SEPHS2/OAT/CYP7A1/HPGD/ACSS2/LIPC/AKR1A1/SHMT2/PHGDH/PSAT1/ENO3/PPARGC1A/ACSM1/ALDOC/RDH10/GCK/ELOVL6/KYNU/CEACAM1/NR1D1/NR1H4/ALOX15B",27,-1.73205080756888]
["BP","GO:0043312","neutrophil degranulation","27/463","485/18670",8.51293842363775e-05,0.00281064273438491,0.00237682975172704,"AHSG/CHI3L1/LYZ/LCN2/ANPEP/PIGR/LAMP1/VNN1/HSPA1A/SLPI/HSPA1B/FUCA1/PYGL/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/CEACAM1/COMMD9/KCNAB2/CD55/PGM2/SLC2A5/NIT2/CRISP3",27,-0.192450089729875]
["BP","GO:0002283","neutrophil activation involved in immune response","27/463","488/18670",9.43186239481528e-05,0.0030167222378417,0.00255110159675555,"AHSG/CHI3L1/LYZ/LCN2/ANPEP/PIGR/LAMP1/VNN1/HSPA1A/SLPI/HSPA1B/FUCA1/PYGL/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/CEACAM1/COMMD9/KCNAB2/CD55/PGM2/SLC2A5/NIT2/CRISP3",27,-0.192450089729875]
["BP","GO:0042119","neutrophil activation","27/463","498/18670",0.000131721160285753,0.00379765091697094,0.00321149663587726,"AHSG/CHI3L1/LYZ/LCN2/ANPEP/PIGR/LAMP1/VNN1/HSPA1A/SLPI/HSPA1B/FUCA1/PYGL/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/CEACAM1/COMMD9/KCNAB2/CD55/PGM2/SLC2A5/NIT2/CRISP3",27,-0.192450089729875]
["BP","GO:0002446","neutrophil mediated immunity","27/463","499/18670",0.000136108317478633,0.00386963508164947,0.00327237029376625,"AHSG/CHI3L1/LYZ/LCN2/ANPEP/PIGR/LAMP1/VNN1/HSPA1A/SLPI/HSPA1B/FUCA1/PYGL/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/CEACAM1/COMMD9/KCNAB2/CD55/PGM2/SLC2A5/NIT2/CRISP3",27,-0.192450089729875]
["BP","GO:0016125","sterol metabolic process","26/463","166/18670",6.05677375538547e-14,1.23982158772741e-10,1.04845941481383e-10,"APOA4/FASN/SCARB1/ACADVL/CYP1B1/HMGCS1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/RXRA/LIPC/LSS/FDFT1/NR0B2/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/SMPD1/MVK/NR1H4/SOAT2/SERPINA12",26,-0.392232270276368]
["BP","GO:0046890","regulation of lipid biosynthetic process","26/463","198/18670",4.04198045346241e-12,2.06848349705939e-09,1.74922022518919e-09,"APOA4/FASN/FGF19/SCARB1/ACADVL/HMGCS1/EGR1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/LSS/FDFT1/PPARGC1A/RDH10/HMGCR/TNFRSF1A/ELOVL6/CEACAM1/PLIN5/NR1D1/MVK/NR1H4/ENHO/SERPINA12",26,0.392232270276368]
["BP","GO:0005996","monosaccharide metabolic process","26/463","292/18670",2.02358509365754e-08,4.87326904319646e-06,4.12109682541155e-06,"UGT2B4/G6PC/IGFBP3/TKFC/CPT1A/DGAT2/H6PD/LRP5/FUCA1/AKR1A1/FGGY/SLC37A4/ENO3/PPARGC1A/UGT2B17/UGT2B11/ALDOC/GCK/UGT1A9/ATF3/GALM/GALT/NR1D1/PGM2/SERPINA12/XYLB",26,-3.13785816221094]
["BP","GO:0016042","lipid catabolic process","26/463","333/18670",2.78609396886187e-07,3.93319610638638e-05,3.32612089422384e-05,"APOA4/PLA2G2A/SCARB1/ACADVL/CYP1B1/CPT1A/CYP7A1/HADHA/FUCA1/LIPC/HADHB/HSD17B11/FGF21/PNPLA2/ACAT2/HSD17B14/NEU4/NAGA/PLA1A/PLIN5/SMPD1/ENPP7/CROT/SLC27A4/PLCH2/ECHDC1",26,-1.1766968108291]
["BP","GO:0043434","response to peptide hormone","26/463","436/18670",3.7094095837512e-05,0.00171939004017031,0.00145400813568512,"AHSG/AGT/REG1A/ERRFI1/EGR1/SREBF1/TNFSF10/HADHA/FGF21/REG1B/PRKACA/KLF15/GCK/NR4A1/BAIAP2/CEACAM1/ADCY1/SYAP1/CISH/AGTR1/STC2/PID1/NR1H4/SLC25A33/ENHO/SERPINA12",26,-1.56892908110547]
["BP","GO:0050727","regulation of inflammatory response","26/463","485/18670",0.000208704986696921,0.00524195224255947,0.00443287504840925,"SAA1/A2M/AHSG/AGT/PLA2G2A/LBP/TGM2/SERPINE1/CREB3L3/CFHR5/PIK3AP1/TNFRSF1A/CPN1/NT5E/CHID1/FNDC4/PER1/CD55/AGTR1/NR1D1/MVK/IL17RC/NR1H4/DUSP10/HGF/IL33",26,-3.92232270276368]
["MF","GO:0048018","receptor ligand activity","26/454","482/17697",0.000316589333996167,0.0101760857355911,0.00882324158906612,"SAA1/AGT/SAA2/NTS/REG1A/FGF19/ANGPTL8/CCL25/TNFSF10/CCL20/CXCL16/FGF21/SST/THBS4/FNDC5/FAM3B/CALCA/GREM2/SEMA3B/TNFSF14/STC2/PROK1/HGF/CXCL13/ENHO/IL33",26,2.35339362165821]
["BP","GO:1902652","secondary alcohol metabolic process","25/463","155/18670",9.31500101732946e-14,1.27118713883156e-10,1.07498380161392e-10,"APOA4/FASN/SCARB1/ACADVL/HMGCS1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/RXRA/LIPC/LSS/FDFT1/NR0B2/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/SMPD1/MVK/NR1H4/SOAT2/SERPINA12",25,-0.6]
["BP","GO:0006694","steroid biosynthetic process","25/463","196/18670",2.01437311228585e-11,9.16315946855363e-09,7.74885750445399e-09,"APOA4/FASN/FGF19/SCARB1/CYP17A1/HMGCS1/EGR1/DHCR7/SREBF1/CYP7A1/IDI1/HSD17B2/LSS/HSD17B11/FDFT1/PPARGC1A/NPC1L1/HMGCR/ACAT2/ELOVL6/HSD17B14/ERG28/NR1D1/MVK/NR1H4",25,-0.2]
["BP","GO:0006790","sulfur compound metabolic process","25/463","372/18670",7.04459304439331e-06,0.000506433840492346,0.000428267529215881,"FASN/ACSL4/GSTA2/HMGCS1/DGAT2/GSTM1/GSTK1/ACSS2/COMT/AKR1A1/PHGDH/CHPF/ACSM1/SUCLG1/ELOVL6/KYNU/NAT8/ACSF2/BTD/ESD/CIAO2A/MVK/HS3ST3B1/SPOCK3/CHAC1",25,-1.8]
["BP","GO:0046486","glycerolipid metabolic process","25/463","414/18670",4.25935023119226e-05,0.00183780224154733,0.00155414382342559,"APOA4/PLA2G2A/G6PC/ACSL4/SCARB1/CPT1A/SERINC2/SREBF1/ETNK2/DGAT2/HADHA/LIPC/HADHB/ALPI/FGF21/CHPT1/PNPLA2/PLA1A/PLIN5/GK/CISH/NR1H4/SLC44A4/PLCH2/SERPINA12",25,-0.6]
["CC","GO:0005759","mitochondrial matrix","25/473","469/19717",0.000183366360903254,0.0087588184019141,0.00791306428353616,"SOD2/ACADVL/OAT/DHRS2/IDH2/GSTK1/ALDH1B1/FH/HADHA/ACSS2/SHMT2/HADHB/MRPL21/CHPF/ACSM1/AK4/PPIF/UQCRC2/SUCLG1/ACSF2/PRODH/BTD/FAHD1/GLRX5/BCKDK",25,-2.2]
["BP","GO:0008203","cholesterol metabolic process","24/463","150/18670",3.52084938673593e-13,3.20953876300777e-10,2.71415755830935e-10,"APOA4/FASN/SCARB1/ACADVL/HMGCS1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/RXRA/LIPC/LSS/FDFT1/NR0B2/NPC1L1/HMGCR/ACAT2/ELOVL6/SMPD1/MVK/NR1H4/SOAT2/SERPINA12",24,-0.408248290463863]
["BP","GO:0010038","response to metal ion","24/463","364/18670",1.47252787966393e-05,0.000873699875267264,0.000738847322076989,"MT1G/IGFBP2/SDC1/TXNIP/CCND1/MT1B/FOS/MT1M/SYT7/HMOX1/MT1F/MT1H/JUN/SOD3/FOSB/PPARGC1A/PPIF/SYT8/BNIP3/AQP3/MT1A/SYT12/ADCY1/ADGRV1",24,-3.2659863237109]
["BP","GO:0048545","response to steroid hormone","24/463","385/18670",3.65660476537396e-05,0.00171939004017031,0.00145400813568512,"IGFBP2/SDC1/ERRFI1/TXNIP/CCND1/TFPI/FOS/SREBF1/CDKN1A/RXRA/BCHE/FOSB/SST/PPARGC1A/NR0B2/AIFM1/CPN1/NR4A1/CRY2/PER1/CCNE1/PGRMC2/NR1D1/NR1H4",24,-3.67423461417477]
["BP","GO:0050708","regulation of protein secretion","24/463","472/18670",0.000766418812159628,0.0143932046650528,0.0121716633181701,"CRP/SAA1/CPT1A/SREBF1/SYT7/IDH2/LRP5/PAEP/AKAP12/NR0B2/GCK/HMGCR/SYBU/MYOM1/PIM3/NR1D1/NADK/SLC25A4/IL17RC/NR1H4/CPTP/ALOX15B/ENHO/IL33",24,-3.2659863237109]
["BP","GO:0072503","cellular divalent inorganic cation homeostasis","24/463","493/18670",0.00138613606287735,0.0227905262707625,0.0192728873845005,"SAA1/AGT/MT1G/TGM2/MT1B/MT1M/MT1F/MT1H/SLC39A5/PRKACA/ATP2B2/BNIP3/HERPUD1/TPCN2/MT1A/CALCA/CD55/AGTR1/STC2/SCGN/KEL/PLCH2/CXCL13/C19orf12",24,-1.22474487139159]
["BP","GO:0002791","regulation of peptide secretion","24/463","500/18670",0.00167161349352202,0.0261205558873251,0.0220889384499556,"CRP/SAA1/CPT1A/SREBF1/SYT7/IDH2/LRP5/PAEP/AKAP12/NR0B2/GCK/HMGCR/SYBU/MYOM1/PIM3/NR1D1/NADK/SLC25A4/IL17RC/NR1H4/CPTP/ALOX15B/ENHO/IL33",24,-3.2659863237109]
["BP","GO:0009141","nucleoside triphosphate metabolic process","23/463","362/18670",3.9518568567008e-05,0.00175857630123186,0.00148714613291635,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/SUCLG1/FAM20C/NADK/PID1/NUDT16/CTPS1/SLC25A33/SMPDL3A/NDUFA5",23,-2.71068738274197]
["BP","GO:0006869","lipid transport","23/463","365/18670",4.48859809675724e-05,0.0018908399668323,0.00159899535929639,"APOA4/AGT/PLA2G2A/LBP/ACSL4/PLIN2/SERPINA5/SCARB1/CPT1A/SYT7/RXRA/LIPC/SIGMAR1/NPC1L1/SLC22A9/CEACAM1/ABCG5/AGTR1/NR1H4/CROT/SLC27A4/CPTP/SOAT2",23,-2.29365855462782]
["BP","GO:0051346","negative regulation of hydrolase activity","23/463","466/18670",0.00144895487825671,0.0234467243936086,0.0198278035971971,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/ANGPTL4/PPP1R1A/PPIF/HERPUD1/CRY2/RARRES1/PLIN5/TNFSF14/SPOCK3/WFDC2/MAP2/ELFN1/HGF/SERPINA12",23,-1.04257207028537]
["BP","GO:0016049","cell growth","23/463","484/18670",0.00235054380755018,0.0337653556074051,0.0285537897803603,"AGT/REG1A/IGFBP3/HSPA1A/HSPA1B/CDKN1A/CXCL16/SGK1/CDHR2/CYFIP2/EI24/CHPT1/CEACAM1/SEMA3B/CISH/AGTR1/NRCAM/GNG4/MAP2/SLC25A33/RND2/SLC44A4/SGK2",23,0.208514414057075]
["BP","GO:0048871","multicellular organismal homeostasis","23/463","485/18670",0.00241219283629695,0.0344094685428562,0.0290984861125277,"LYZ/LCN2/MUC13/PIGR/UBB/ACADVL/G0S2/EGR1/FH/MET/FGF21/PPARGC1A/PRKACA/AQP3/TP53INP2/ELOVL6/HOMER2/ADCY1/CALCA/NR1D1/VSIG1/TFF2/ADGRV1",23,-1.04257207028537]
["CC","GO:0060205","cytoplasmic vesicle lumen","23/473","338/19717",7.95789123008578e-06,0.00106050909933662,0.000958106024265992,"SAA1/A2M/AHSG/CHI3L1/LYZ/LCN2/SERPINE1/SLPI/SCCPDH/FUCA1/PYGL/PCSK1/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/COMMD9/PGM2/NIT2/HGF/CRISP3",23,-0.625543242171224]
["CC","GO:0031983","vesicle lumen","23/473","339/19717",8.35046534910727e-06,0.00106050909933662,0.000958106024265992,"SAA1/A2M/AHSG/CHI3L1/LYZ/LCN2/SERPINE1/SLPI/SCCPDH/FUCA1/PYGL/PCSK1/OLFM4/GUSB/HSPA6/ALDOC/HBB/TOLLIP/COMMD9/PGM2/NIT2/HGF/CRISP3",23,-0.625543242171224]
["MF","GO:0050662","coenzyme binding","23/454","291/17697",1.93292426094852e-06,0.000434907958713417,0.000377089785644694,"FASN/ACADVL/OAT/DHCR7/IDH2/H6PD/HPGD/ALDH1B1/HADHA/PYGL/SHMT2/PHGDH/SDHA/P4HA1/AIFM1/HMGCR/GCAT/CHDH/KYNU/CRY2/PRODH/DDC/SOAT2",23,-2.29365855462782]
["BP","GO:0019218","regulation of steroid metabolic process","22/463","124/18670",3.91980796654588e-13,3.20953876300777e-10,2.71415755830935e-10,"APOA4/AGT/FASN/FGF19/ACADVL/HMGCS1/EGR1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/LSS/FDFT1/PPARGC1A/HMGCR/ELOVL6/AGTR1/NR1D1/MVK/NR1H4/SERPINA12",22,-0.426401432711221]
["BP","GO:0042445","hormone metabolic process","22/463","232/18670",8.30896305061857e-08,1.41737061371802e-05,1.19860436287213e-05,"CYP3A5/CYP3A7/CYP2D6/SCARB1/CYP17A1/CYP1B1/EGR1/DHRS2/DHCR7/DGAT2/HSD17B2/COMT/PCSK1/HSD17B11/PPARGC1A/UGT2B11/RDH10/RDH11/UGT1A9/HSD17B14/STC2/SLC44A4",22,0]
["BP","GO:0097237","cellular response to toxic substance","22/463","247/18670",2.49555768751239e-07,3.64886184738419e-05,3.08567264444671e-05,"APOA4/SOD2/LCN2/CYP1B1/EGR1/HMOX1/GSTM1/GSTK1/MET/PRXL2A/AKR1A1/SIGMAR1/SOD3/PPARGC1A/PPIF/RDH11/AIFM1/BNIP3/HBB/CYGB/ESD/HGF",22,-1.70560573084488]
["BP","GO:0015980","energy derivation by oxidation of organic compounds","22/463","285/18670",2.78376301210112e-06,0.000248444179779733,0.000210097680121241,"COX3/ND2/G6PC/ACADVL/IDH2/FH/PYGL/SHMT2/PPP1R1A/SDHA/PPARGC1A/ACSM1/UQCRC2/GCK/BNIP3/SUCLG1/SLC25A18/FAHD1/NR1D1/PGM2/PID1/NDUFA5",22,-3.41121146168977]
["BP","GO:0009161","ribonucleoside monophosphate metabolic process","22/463","354/18670",8.02342316611028e-05,0.00269245036410291,0.00227687996491257,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NT5E/UPP2/NADK/PID1/MPP1/SLC25A33/NDUFA5",22,-1.70560573084488]
["BP","GO:0032102","negative regulation of response to external stimulus","22/463","365/18670",0.000124967396674923,0.00370736610135605,0.00313514696921298,"SAA1/SERPINE1/TFPI/TKFC/CDKN1A/TSPAN8/TRIB1/TSPAN6/HMGCR/TNFRSF1A/NT5E/CEACAM1/CHID1/FNDC4/CD9/SEMA3B/NR1D1/MVK/NR1H4/DUSP10/HGF/CXCL13",22,-2.55840859626733]
["BP","GO:0009123","nucleoside monophosphate metabolic process","22/463","375/18670",0.000183558473720755,0.0047865502637756,0.00404776278959143,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NT5E/UPP2/NADK/PID1/MPP1/SLC25A33/NDUFA5",22,-1.70560573084488]
["BP","GO:0001558","regulation of cell growth","22/463","416/18670",0.000754282285269219,0.0142305607183971,0.0120341229020153,"AGT/REG1A/IGFBP3/HSPA1A/HSPA1B/CDKN1A/CXCL16/SGK1/CDHR2/EI24/CHPT1/CEACAM1/SEMA3B/CISH/AGTR1/NRCAM/GNG4/MAP2/SLC25A33/RND2/SLC44A4/SGK2",22,0.426401432711221]
["BP","GO:0023061","signal release","22/463","462/18670",0.00282607563502304,0.0390876812492713,0.0330546328719444,"AGT/CPT1A/SREBF1/SYT7/LRP5/NR0B2/SYT8/GCK/HMGCR/SYBU/FAM3B/SYT12/ADCY1/PIM3/AGTR1/NR1D1/NADK/CHRNA4/SLC25A4/NR1H4/SLC44A4/ENHO",22,-2.1320071635561]
["BP","GO:0042326","negative regulation of phosphorylation","22/463","468/18670",0.00329854813055692,0.0439878047117265,0.0371984392299047,"AHSG/ERRFI1/IGFBP3/JUN/CDKN1A/LRP5/TRIB1/PPARGC1A/PPIF/DUSP6/HMGCR/FBXO7/ATF3/CEACAM1/PER1/EPHA1/GPRC5A/SMPD1/PID1/DUSP5/DUSP10/HGF",22,-4.26401432711221]
["BP","GO:1901617","organic hydroxy compound biosynthetic process","21/463","271/18670",4.40754320383409e-06,0.000360889637529935,0.000305187570471796,"APOA4/FASN/FGF19/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/PSAT1/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/DDC/NR1D1/MVK/NR1H4/PLCH2",21,-0.218217890235992]
["BP","GO:0034599","cellular response to oxidative stress","21/463","302/18670",2.2977892145183e-05,0.00119077836003012,0.00100698583964699,"APOA4/SOD2/LCN2/CYP1B1/FOS/VNN1/DHRS2/HSPA1A/HMOX1/HSPA1B/JUN/MET/SIGMAR1/SOD3/PPARGC1A/PPIF/AIFM1/BNIP3/FBXO7/PRODH/HGF",21,-0.654653670707977]
["BP","GO:0009167","purine ribonucleoside monophosphate metabolic process","21/463","340/18670",0.000126392262312677,0.00372266130869136,0.00314808141420972,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NT5E/NADK/PID1/MPP1/SLC25A33/NDUFA5",21,-1.96396101212393]
["BP","GO:0009126","purine nucleoside monophosphate metabolic process","21/463","341/18670",0.000131657310945495,0.00379765091697094,0.00321149663587726,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NT5E/NADK/PID1/MPP1/SLC25A33/NDUFA5",21,-1.96396101212393]
["BP","GO:1901653","cellular response to peptide","21/463","385/18670",0.0006665728575289,0.0132473265957443,0.0112026475647039,"AHSG/AGT/REG1A/ERRFI1/SREBF1/FGF21/PRKACA/KLF15/GCK/NR4A1/BAIAP2/CEACAM1/ADCY1/SYAP1/CISH/AGTR1/PID1/NR1H4/SLC25A33/ENHO/SERPINA12",21,-1.52752523165195]
["BP","GO:0043062","extracellular structure organization","21/463","422/18670",0.00207969636449718,0.0311878275320567,0.0263740942465056,"A2M/APOA4/AGT/PLA2G2A/SDC1/SERPINE1/SDC4/SCARB1/CYP1B1/LIPC/VWA1/LAMB3/PRKACA/COL5A3/P4HA1/TNFRSF1A/SCUBE1/MMP1/ADAMTSL4/AGTR1/SOAT2",21,0.218217890235992]
["BP","GO:0006644","phospholipid metabolic process","21/463","430/18670",0.002598958771648,0.0368170837755257,0.0311344942631589,"APOA4/PLA2G2A/SCARB1/HMGCS1/SERINC2/ETNK2/HADHA/IDI1/LIPC/HADHB/ALPI/FDFT1/CHPT1/PLA1A/CISH/SMPD1/MVK/ENPP7/NR1H4/SLC44A4/PLCH2",21,0.218217890235992]
["CC","GO:0034774","secretory granule lumen","21/473","321/19717",3.51129045589975e-05,0.00334450415924451,0.00302155783968215,"A2M/AHSG/CHI3L1/LYZ/LCN2/SERPINE1/SLPI/SCCPDH/FUCA1/PYGL/PCSK1/OLFM4/GUSB/HSPA6/ALDOC/TOLLIP/COMMD9/PGM2/NIT2/HGF/CRISP3",21,-0.218217890235992]
["BP","GO:0044242","cellular lipid catabolic process","20/463","217/18670",5.09885881066935e-07,6.73378321641301e-05,5.69444707242496e-05,"APOA4/SCARB1/ACADVL/CYP1B1/CPT1A/HADHA/FUCA1/LIPC/HADHB/FGF21/PNPLA2/ACAT2/NEU4/NAGA/PLIN5/SMPD1/ENPP7/CROT/SLC27A4/ECHDC1",20,-1.78885438199983]
["BP","GO:0030258","lipid modification","20/463","238/18670",2.17479225837556e-06,0.000205587041914165,0.000173855393221322,"APOA4/AGT/CYP3A5/CYP3A7/ACADVL/CPT1A/DGAT2/HADHA/HADHB/SLC35C1/PPARGC1A/ACSM1/ACAT2/CYGB/PLIN5/CISH/AGTR1/CROT/SOAT2/ECHDC1",20,-2.68328157299975]
["BP","GO:0019318","hexose metabolic process","20/463","249/18670",4.33668632988894e-06,0.000360889637529935,0.000305187570471796,"G6PC/IGFBP3/TKFC/CPT1A/DGAT2/H6PD/LRP5/FUCA1/AKR1A1/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/GALM/GALT/NR1D1/PGM2/SERPINA12",20,-3.13049516849971]
["BP","GO:0071375","cellular response to peptide hormone stimulus","20/463","321/18670",0.000162086164844595,0.00442233690499891,0.00373976450274893,"AHSG/AGT/REG1A/ERRFI1/SREBF1/FGF21/PRKACA/GCK/NR4A1/BAIAP2/CEACAM1/ADCY1/SYAP1/CISH/AGTR1/PID1/NR1H4/SLC25A33/ENHO/SERPINA12",20,-1.78885438199983]
["BP","GO:0009914","hormone transport","20/463","322/18670",0.00016893944687738,0.00450297175558853,0.00380795364310561,"AGT/SERPINA7/CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SLC22A9/SYBU/FAM3B/PIM3/AGTR1/NR1D1/NADK/SLC25A4/NR1H4/SLC44A4/ENHO",20,-2.23606797749979]
["BP","GO:0071496","cellular response to external stimulus","20/463","339/18670",0.0003314292378847,0.00745533681263715,0.00630463136728038,"AGT/LCN2/FOS/SREBF1/HMOX1/JUN/CDKN1A/SLC39A5/COMT/AIFM1/BNIP3/AQP3/TNFRSF1A/ATF3/BAIAP2/BAG3/PIM1/TNFSF14/FES/NR1H4",20,-3.13049516849971]
["BP","GO:0009199","ribonucleoside triphosphate metabolic process","20/463","341/18670",0.000357489328478664,0.00799760279121122,0.00676320046802604,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NADK/PID1/CTPS1/SLC25A33/NDUFA5",20,-2.23606797749979]
["BP","GO:0009144","purine nucleoside triphosphate metabolic process","20/463","342/18670",0.000371177142432652,0.00825869141912652,0.00698399096945649,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NADK/PID1/NUDT16/SLC25A33/NDUFA5",20,-2.23606797749979]
["BP","GO:0072330","monocarboxylic acid biosynthetic process","20/463","343/18670",0.000385319816920438,0.0084811791960875,0.0071721385277381,"APOA4/FASN/CYP2D6/FGF19/ACADVL/CYP7A1/HPGD/ACSS2/LIPC/ENO3/PPARGC1A/ACSM1/ALDOC/RDH10/GCK/ELOVL6/CEACAM1/NR1D1/NR1H4/ALOX15B",20,-0.894427190999916]
["MF","GO:0004857","enzyme inhibitor activity","20/454","375/17697",0.00173254213244044,0.040326411703355,0.0349652786075094,"A2M/AHSG/AGT/ITIH2/SERPINA5/TXNIP/SERPINE1/SERPINA7/TFPI/SLPI/ANGPTL4/CDKN1A/TRIB1/PPP1R1A/RARRES1/TNFSF14/SPOCK3/WFDC2/ELFN1/SERPINA12",20,-1.78885438199983]
["BP","GO:0071241","cellular response to inorganic substance","19/463","217/18670",2.12413589506554e-06,0.000205587041914165,0.000173855393221322,"MT1G/MT1B/FOS/MT1M/SYT7/HMOX1/MT1F/MT1H/JUN/FOSB/PPARGC1A/PPIF/SYT8/AIFM1/BNIP3/MT1A/SYT12/ADCY1/ADGRV1",19,-2.9824045403173]
["BP","GO:0042180","cellular ketone metabolic process","19/463","248/18670",1.4718134206299e-05,0.000873699875267264,0.000738847322076989,"APOA4/FGF19/ACADVL/CYP17A1/CPT1A/EGR1/SREBF1/DGAT2/CYP7A1/COMT/AKR1A1/PPARGC1A/RDH10/HMGCR/KYNU/CEACAM1/PLIN5/NR1D1/NR1H4",19,-1.60591013709393]
["BP","GO:0016054","organic acid catabolic process","19/463","275/18670",6.09531465481598e-05,0.00222805519614434,0.00188416258455731,"ACADVL/OAT/CPT1A/HADHA/AKR1A1/SHMT2/HADHB/GUSB/GCAT/ACAT2/KYNU/PRODH/PLIN5/NPL/CROT/BCKDK/SLC27A4/ECHDC1/XYLB",19,-2.9824045403173]
["BP","GO:0046395","carboxylic acid catabolic process","19/463","275/18670",6.09531465481598e-05,0.00222805519614434,0.00188416258455731,"ACADVL/OAT/CPT1A/HADHA/AKR1A1/SHMT2/HADHB/GUSB/GCAT/ACAT2/KYNU/PRODH/PLIN5/NPL/CROT/BCKDK/SLC27A4/ECHDC1/XYLB",19,-2.9824045403173]
["BP","GO:0009410","response to xenobiotic stimulus","19/463","292/18670",0.000134531616439047,0.0038515555084018,0.00325708124010324,"CYP3A5/CYP3A7/ERRFI1/GSTA2/CYP2D6/CYP2A7/CYP1B1/EGR1/GSTM1/PHGDH/BCHE/FOSB/PPARGC1A/ACSM1/UGT2B11/UGT1A9/HOMER2/SMPD1/CYP2D7",19,-2.9824045403173]
["BP","GO:0046034","ATP metabolic process","19/463","305/18670",0.000235253925750187,0.0055672229596605,0.004707941355597,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NADK/PID1/SLC25A33/NDUFA5",19,-2.06474160483506]
["BP","GO:0032496","response to lipopolysaccharide","19/463","330/18670",0.000623626102320531,0.0126752303666031,0.0107188524093687,"LBP/LCN2/SERPINE1/TFPI/SCARB1/FOS/SLPI/JUN/HPGD/TRIB1/COMT/AKAP12/PPARGC1A/MRC1/CD55/NR1D1/NR1H4/DUSP10/CXCL13",19,-2.52357307257618]
["BP","GO:0015849","organic acid transport","19/463","333/18670",0.000695393337200626,0.0133034594509316,0.0112501165078842,"AGT/PLA2G2A/ACSL4/PLIN2/CPT1A/RXRA/SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/NR1H4/CROT/SLC6A11/SLC27A4/SLC16A13/SLC16A9",19,-1.14707866935281]
["BP","GO:0046942","carboxylic acid transport","19/463","333/18670",0.000695393337200626,0.0133034594509316,0.0112501165078842,"AGT/PLA2G2A/ACSL4/PLIN2/CPT1A/RXRA/SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/NR1H4/CROT/SLC6A11/SLC27A4/SLC16A13/SLC16A9",19,-1.14707866935281]
["BP","GO:0009205","purine ribonucleoside triphosphate metabolic process","19/463","335/18670",0.000747097953338913,0.0141602732452292,0.011974684057172,"COX3/ND2/MYH4/HSPA1A/HSPA1B/SHMT2/SDHA/ENO3/PPARGC1A/AK4/PPIF/ALDOC/UQCRC2/GCK/FAM20C/NADK/PID1/SLC25A33/NDUFA5",19,-2.06474160483506]
["BP","GO:0001101","response to acid chemical","19/463","343/18670",0.000988382348584617,0.0175170447407161,0.0148133494850527,"REG1A/IGFBP2/CPT1A/EGR1/SREBF1/DGAT2/RXRA/HSD17B2/SHMT2/BCHE/FGF21/SST/PPARGC1A/AIFM1/AQP3/BAIAP2/CD9/PID1/NR1H4",19,-2.52357307257618]
["BP","GO:0002237","response to molecule of bacterial origin","19/463","343/18670",0.000988382348584617,0.0175170447407161,0.0148133494850527,"LBP/LCN2/SERPINE1/TFPI/SCARB1/FOS/SLPI/JUN/HPGD/TRIB1/COMT/AKAP12/PPARGC1A/MRC1/CD55/NR1D1/NR1H4/DUSP10/CXCL13",19,-2.52357307257618]
["BP","GO:0045861","negative regulation of proteolysis","19/463","363/18670",0.00190001601620226,0.0290248715310898,0.0245449830215602,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/TM4SF20/HERPUD1/CD55/RARRES1/TNFSF14/SPOCK3/WFDC2/HGF/CHAC1/SERPINA12",19,-0.688247201611685]
["BP","GO:0035690","cellular response to drug","19/463","369/18670",0.00228396687659218,0.0332760156326276,0.0281399777378223,"LCN2/ERRFI1/CYP1B1/EGR1/HMOX1/MET/SIGMAR1/FGF21/PPARGC1A/PPIF/AIFM1/BNIP3/BAIAP2/ADCY1/DCPS/DDC/CHRNA4/HGF/KCNH2",19,-1.60591013709393]
["CC","GO:0005788","endoplasmic reticulum lumen","19/473","309/19717",0.000183912197415519,0.0087588184019141,0.00791306428353616,"AHSG/APOA4/ITIH2/IGFBP3/H6PD/LIPC/VWA1/BCHE/BPIFB2/ARSL/COL5A3/P4HA1/FAM20C/PNPLA2/MSLN/ADAMTSL4/ESD/STC2/PDIA5",19,-0.688247201611685]
["BP","GO:0034754","cellular hormone metabolic process","18/463","129/18670",3.17191328654043e-09,8.65720866339767e-07,7.32099845574138e-07,"CYP3A5/CYP3A7/CYP2D6/SCARB1/CYP17A1/CYP1B1/EGR1/DHRS2/DGAT2/HSD17B2/COMT/HSD17B11/PPARGC1A/UGT2B11/RDH10/RDH11/UGT1A9/HSD17B14",18,-0.942809041582063]
["BP","GO:0071248","cellular response to metal ion","18/463","190/18670",1.27043749283917e-06,0.000137103276214768,0.000115941859838627,"MT1G/MT1B/FOS/MT1M/SYT7/HMOX1/MT1F/MT1H/JUN/FOSB/PPARGC1A/PPIF/SYT8/BNIP3/MT1A/SYT12/ADCY1/ADGRV1",18,-2.82842712474619]
["BP","GO:0007584","response to nutrient","18/463","219/18670",9.48915187505815e-06,0.000636862094696526,0.000538564633599073,"IGFBP2/ACSL4/CCND1/HMGCS1/HMOX1/BCHE/SST/AIFM1/HMGCR/AQP3/BAIAP2/KYNU/PIM1/ABCG5/STC2/FES/NR1H4/SLC27A4",18,-2.35702260395516]
["BP","GO:0000302","response to reactive oxygen species","18/463","232/18670",2.07852258113424e-05,0.00111966729567942,0.000946850522070709,"APOA4/SOD2/LCN2/SDC1/TXNIP/CYP1B1/FOS/HMOX1/JUN/MET/SIGMAR1/SOD3/PPARGC1A/PPIF/AIFM1/BNIP3/HBB/HGF",18,-1.88561808316413]
["BP","GO:0045926","negative regulation of growth","18/463","249/18670",5.29203712262105e-05,0.00204115243711116,0.0017261076197924,"AGT/MT1G/MT1B/MT1M/HSPA1A/MT1F/MT1H/HSPA1B/CDKN1A/CDHR2/EI24/MT1A/SEMA3B/STC2/GNG4/MAP2/DUSP10/ALOX15B",18,-0.471404520791032]
["BP","GO:0032868","response to insulin","18/463","272/18670",0.000162775421408163,0.00442233690499891,0.00373976450274893,"AHSG/AGT/ERRFI1/EGR1/SREBF1/TNFSF10/HADHA/KLF15/GCK/BAIAP2/CEACAM1/SYAP1/CISH/PID1/NR1H4/SLC25A33/ENHO/SERPINA12",18,-1.88561808316413]
["BP","GO:0060326","cell chemotaxis","18/463","304/18670",0.000621778778529578,0.0126752303666031,0.0107188524093687,"SAA1/SAA2/LBP/SERPINE1/CCL25/MET/CCL20/CXCL16/THBS4/NR4A1/CALCA/EPHA2/TNFSF14/AGTR1/IL17RC/MPP1/HGF/CXCL13",18,0]
["BP","GO:0046879","hormone secretion","18/463","312/18670",0.000839623554415652,0.0153456197847218,0.01297707645899,"AGT/CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/FAM3B/PIM3/AGTR1/NR1D1/NADK/SLC25A4/NR1H4/SLC44A4/ENHO",18,-2.35702260395516]
["BP","GO:0046677","response to antibiotic","18/463","327/18670",0.00142686656339067,0.023180919486196,0.0196030247576939,"LCN2/SDC1/TXNIP/CCND1/CYP1B1/EGR1/HMOX1/JUN/HPGD/MET/SIGMAR1/PPIF/AIFM1/BNIP3/HMGCR/HBB/ADCY1/HGF",18,-2.82842712474619]
["BP","GO:0001505","regulation of neurotransmitter levels","18/463","354/18670",0.00336279291611143,0.0444105619308393,0.0375559453347724,"AGT/CYP1B1/SYT7/COMT/SHMT2/PHGDH/BCHE/SYT8/GCAT/HBB/CHDH/SYT12/ADCY1/SLC1A7/DDC/CHRNA4/SLC6A11/SLC44A4",18,-1.4142135623731]
["CC","GO:0016324","apical plasma membrane","18/473","318/19717",0.000719419177599766,0.0249180642423192,0.0225119685239353,"IGFBP2/MUC13/CDHR5/AKR1A1/SLC22A18/CDHR2/NPC1L1/ITPK1/AMN/SHROOM1/CEACAM1/CD9/PTPRH/ABCG5/UPK3A/CEACAM5/SLC2A5/SLC44A4",18,0]
["BP","GO:0098754","detoxification","17/463","131/18670",2.64170903860937e-08,6.00842044670376e-06,5.08104153683405e-06,"APOA4/MT1G/SOD2/MT1B/MT1M/MT1F/MT1H/GSTM1/GSTK1/PRXL2A/AKR1A1/SOD3/RDH11/MT1A/HBB/CYGB/ESD",17,-1.69774937525433]
["BP","GO:0006720","isoprenoid metabolic process","17/463","139/18670",6.43800013509787e-08,1.14596402404742e-05,9.69088441388417e-06,"APOA4/SDC1/CYP3A5/CYP3A7/CYP2D6/SDC4/CYP1B1/HMGCS1/DGAT2/IDI1/LSS/FDFT1/RDH10/RDH11/HMGCR/UGT1A9/MVK",17,-0.727606875108999]
["BP","GO:0045834","positive regulation of lipid metabolic process","17/463","146/18670",1.33182364730923e-07,2.1809944048336e-05,1.84436546357898e-05,"APOA4/AGT/SCARB1/CPT1A/EEF1A2/SREBF1/DGAT2/CYP7A1/FGF21/PPARGC1A/RDH10/PNPLA2/TNFRSF1A/PLIN5/AGTR1/NR1D1/NR1H4",17,-0.727606875108999]
["BP","GO:0016052","carbohydrate catabolic process","17/463","199/18670",1.00826306013568e-05,0.000665778865837978,0.000563018201152163,"G6PC/TKFC/LRP5/PYGL/AKR1A1/GUSB/ENO3/PPARGC1A/ALDOC/GCK/NEU4/GALM/NAGA/GALT/GK/PGM2/XYLB",17,-3.63803437554499]
["BP","GO:0009746","response to hexose","17/463","202/18670",1.22792346448716e-05,0.000785487291189128,0.000664250045180635,"TXNIP/EGR1/SREBF1/CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",17,-2.182820625327]
["BP","GO:0034284","response to monosaccharide","17/463","207/18670",1.69021407406782e-05,0.000974610763272343,0.000824182963618836,"TXNIP/EGR1/SREBF1/CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",17,-2.182820625327]
["BP","GO:0006006","glucose metabolic process","17/463","209/18670",1.91484459917905e-05,0.00108880191514431,0.000920749106242674,"G6PC/IGFBP3/CPT1A/DGAT2/H6PD/LRP5/AKR1A1/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/GALM/NR1D1/PGM2/SERPINA12",17,-2.66789187539966]
["BP","GO:0009743","response to carbohydrate","17/463","230/18670",6.45190082979401e-05,0.00232458580243499,0.0019657940257138,"TXNIP/EGR1/SREBF1/CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",17,-2.182820625327]
["BP","GO:0042593","glucose homeostasis","17/463","241/18670",0.000114514051382391,0.00349866064447394,0.00295865447758589,"G6PC/CYP7A1/LRP5/PYGL/FGF21/PPARGC1A/PRKACA/KLF15/GCK/HMGCR/SYBU/FAM3B/CRY2/PIM3/NR1D1/NADK/NR1H4",17,-1.21267812518166]
["BP","GO:0033500","carbohydrate homeostasis","17/463","242/18670",0.00012041314715789,0.0035983315654336,0.00304294153670612,"G6PC/CYP7A1/LRP5/PYGL/FGF21/PPARGC1A/PRKACA/KLF15/GCK/HMGCR/SYBU/FAM3B/CRY2/PIM3/NR1D1/NADK/NR1H4",17,-1.21267812518166]
["BP","GO:0030522","intracellular receptor signaling pathway","17/463","280/18670",0.000660128649605321,0.0131832521535814,0.0111484627910239,"UBB/TKFC/HSPA1A/SREBF1/HSPA1B/RXRA/PPARGC1A/TSPAN6/NR4A1/CRY2/PER1/PIM1/CCNE1/PLIN5/NR1D1/NR1H4/ALOX15B",17,-1.21267812518166]
["BP","GO:0044262","cellular carbohydrate metabolic process","17/463","286/18670",0.000835746469041129,0.0153432558038313,0.0129750773503718,"G6PC/IGFBP3/TKFC/IDH2/DGAT2/PYGL/PPP1R1A/FGGY/GUSB/PPARGC1A/GCK/ITPK1/GK/NR1D1/PGM2/SERPINA12/XYLB",17,-2.182820625327]
["MF","GO:0016614","oxidoreductase activity, acting on CH-OH group of donors","17/454","128/17697",3.01455294390285e-08,2.03482323713443e-05,1.76430677558946e-05,"FASN/DHRS2/IDH2/H6PD/HPGD/HADHA/HSD17B2/AKR1A1/HADHB/PHGDH/HSD17B11/RDH10/RDH11/HMGCR/HSD17B14/CHDH/KCNAB2",17,-1.21267812518166]
["BP","GO:0050810","regulation of steroid biosynthetic process","16/463","95/18670",1.44618923159186e-09,4.55438362625928e-07,3.85143026939726e-07,"FASN/FGF19/HMGCS1/EGR1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/PPARGC1A/HMGCR/ELOVL6/NR1D1/MVK/NR1H4",16,0]
["BP","GO:0055088","lipid homeostasis","16/463","151/18670",1.12595263534862e-06,0.000128045835808812,0.000108282404025193,"APOA4/G6PC/SCARB1/ANGPTL8/DGAT2/ANGPTL4/CYP7A1/LRP5/LIPC/ACSM1/PNPLA2/COMMD9/ABCG5/NR1D1/NR1H4/SOAT2",16,-0.5]
["BP","GO:0046165","alcohol biosynthetic process","16/463","175/18670",7.7797715642766e-06,0.000539837030239803,0.000456515052183867,"APOA4/FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/MVK/PLCH2",16,0.5]
["BP","GO:0006986","response to unfolded protein","16/463","176/18670",8.36623342431977e-06,0.000570855993986085,0.000482746346185749,"CCND1/CREB3L3/ACADVL/AGR2/HSPA1A/HSPA1B/DNAJB1/HSPA6/FGF21/THBS4/HERPUD1/ATF3/BAG3/STC2/PDIA5/CHAC1",16,1]
["BP","GO:0071466","cellular response to xenobiotic stimulus","16/463","180/18670",1.11266753287901e-05,0.000723057282477252,0.000611455892337356,"CYP3A5/CYP3A7/ERRFI1/GSTA2/CYP2D6/CYP2A7/CYP1B1/EGR1/GSTM1/PHGDH/BCHE/PPARGC1A/ACSM1/UGT2B11/UGT1A9/CYP2D7",16,-2.5]
["BP","GO:0009749","response to glucose","16/463","197/18670",3.4117243300784e-05,0.00164324698909894,0.00138961750113039,"TXNIP/EGR1/SREBF1/CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/NR1H4",16,-2.5]
["BP","GO:0035966","response to topologically incorrect protein","16/463","199/18670",3.85784248127387e-05,0.00174534552203355,0.00147595747871554,"CCND1/CREB3L3/ACADVL/AGR2/HSPA1A/HSPA1B/DNAJB1/HSPA6/FGF21/THBS4/HERPUD1/ATF3/BAG3/STC2/PDIA5/CHAC1",16,1]
["BP","GO:0010951","negative regulation of endopeptidase activity","16/463","250/18670",0.000535190230862195,0.0111789224752542,0.00945349446458518,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/HERPUD1/RARRES1/TNFSF14/SPOCK3/WFDC2/HGF/SERPINA12",16,-1]
["BP","GO:0010466","negative regulation of peptidase activity","16/463","262/18670",0.00088536073714468,0.0160383489286297,0.0135628852560263,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/HERPUD1/RARRES1/TNFSF14/SPOCK3/WFDC2/HGF/SERPINA12",16,-1]
["BP","GO:0015850","organic hydroxy compound transport","16/463","262/18670",0.00088536073714468,0.0160383489286297,0.0135628852560263,"APOA4/AGT/SCARB1/SYT7/RXRA/LIPC/SYT8/NPC1L1/AQP3/CEACAM1/SYT12/ABCG5/AGTR1/CHRNA4/NR1H4/SOAT2",16,-1.5]
["BP","GO:0046883","regulation of hormone secretion","16/463","266/18670",0.00103875399992187,0.0181357946644326,0.0153365974986036,"AGT/CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/PIM3/AGTR1/NR1D1/NADK/SLC25A4/NR1H4/ENHO",16,-3]
["BP","GO:0048511","rhythmic process","16/463","295/18670",0.00297368093178087,0.0408531870292312,0.0345476389425196,"ATF5/SERPINE1/CPT1A/EGR1/SREBF1/JUN/PPARGC1A/NR0B2/CRY2/PER1/ADCY1/DDC/NFIL3/NR1D1/TEF/PROK1",16,-2.5]
["BP","GO:0002758","innate immune response-activating signal transduction","16/463","298/18670",0.00328323105221298,0.0439878047117265,0.0371984392299047,"LBP/MUC13/MUC5B/UBB/TKFC/HSPA1A/HSPA1B/MUC5AC/GRAMD4/PRKACA/PIK3AP1/TSPAN6/MUCL1/S100A1/NR1D1/NR1H4",16,-0.5]
["MF","GO:0016616","oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor","16/454","119/17697",6.45508329575979e-08,2.17859061231893e-05,1.88896121707497e-05,"FASN/DHRS2/IDH2/H6PD/HPGD/HADHA/HSD17B2/AKR1A1/HADHB/PHGDH/HSD17B11/RDH10/RDH11/HMGCR/HSD17B14/KCNAB2",16,-1]
["MF","GO:0016829","lyase activity","16/454","187/17697",2.69168023657284e-05,0.00227110519960834,0.00196917659412434,"FASN/CYP17A1/TKFC/APMAP/FH/HADHA/SHMT2/HADHB/ENO3/ALDOC/ADCY1/FAHD1/DDC/NPL/CHAC1/ECHDC1",16,-1.5]
["MF","GO:0016746","transferase activity, transferring acyl groups","16/454","264/17697",0.00135661864503254,0.0339154661258136,0.0294066263796528,"FASN/TGM2/CPT1A/HMGCS1/DGAT2/HADHA/HADHB/ACSM1/GCAT/SPTSSA/ACAT2/ELOVL6/NAT8/TGM3/CROT/SOAT2",16,-1]
["KEGG","hsa01200","Carbon metabolism","16/268","118/8076",1.53921553040266e-06,0.000216259782021574,0.000174174388966617,"TKFC/IDH2/H6PD/FH/HADHA/ACSS2/SHMT2/PHGDH/SDHA/PSAT1/ENO3/ALDOC/GCK/SUCLG1/ACAT2/ESD",16,-2.5]
["BP","GO:0090181","regulation of cholesterol metabolic process","15/463","63/18670",2.70448760575084e-11,1.10721722579439e-08,9.36322077401528e-09,"FASN/ACADVL/HMGCS1/DHCR7/SREBF1/DGAT2/CYP7A1/IDI1/LSS/FDFT1/HMGCR/ELOVL6/MVK/NR1H4/SERPINA12",15,0.258198889747161]
["BP","GO:1902653","secondary alcohol biosynthetic process","15/463","76/18670",4.68211018290619e-10,1.74259628080163e-07,1.47363257335679e-07,"APOA4/FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/MVK",15,0.258198889747161]
["BP","GO:0016126","sterol biosynthetic process","15/463","81/18670",1.19829230007589e-09,4.08817389709226e-07,3.45717839907861e-07,"APOA4/FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/NPC1L1/HMGCR/ACAT2/ELOVL6/ERG28/MVK",15,0.258198889747161]
["BP","GO:0010565","regulation of cellular ketone metabolic process","15/463","181/18670",4.73206627005828e-05,0.001899321500943,0.00160616779795889,"APOA4/FGF19/ACADVL/CPT1A/EGR1/SREBF1/DGAT2/CYP7A1/COMT/PPARGC1A/RDH10/CEACAM1/PLIN5/NR1D1/NR1H4",15,-1.29099444873581]
["BP","GO:0006575","cellular modified amino acid metabolic process","15/463","202/18670",0.000163110130106213,0.00442233690499891,0.00373976450274893,"PLA2G2A/GSTA2/CPT1A/SERINC2/VNN1/GSTM1/GSTK1/SHMT2/P4HA1/CHDH/NAT8/PRODH/PLA1A/CROT/CHAC1",15,-1.29099444873581]
["BP","GO:0097164","ammonium ion metabolic process","15/463","205/18670",0.000191734556626544,0.00493686336370486,0.00417487558255349,"APOA4/PLA2G2A/SCARB1/CPT1A/COMT/LIPC/AKR1A1/BCHE/CHPT1/CHDH/DDC/SMPD1/ENPP7/CROT/SLC44A4",15,-1.29099444873581]
["BP","GO:0030073","insulin secretion","15/463","207/18670",0.000213149139465337,0.00528868228467327,0.00447239247018496,"CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/FAM3B/PIM3/NR1D1/NADK/SLC25A4/NR1H4/ENHO",15,-2.32379000772445]
["BP","GO:0007623","circadian rhythm","15/463","208/18670",0.00022461112849239,0.00540916447086968,0.00457427864774905,"ATF5/SERPINE1/CPT1A/EGR1/SREBF1/JUN/PPARGC1A/NR0B2/CRY2/PER1/ADCY1/DDC/NFIL3/NR1D1/PROK1",15,-2.84018778721877]
["BP","GO:0030072","peptide hormone secretion","15/463","250/18670",0.00151079908096937,0.0242557311274062,0.0205119429403849,"CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/FAM3B/PIM3/NR1D1/NADK/SLC25A4/NR1H4/ENHO",15,-2.32379000772445]
["BP","GO:0031668","cellular response to extracellular stimulus","15/463","268/18670",0.00295314761845581,0.040707698148007,0.0344246057667948,"LCN2/FOS/SREBF1/HMOX1/JUN/CDKN1A/SLC39A5/COMT/AIFM1/AQP3/ATF3/BAIAP2/PIM1/FES/NR1H4",15,-3.35658556671309]
["MF","GO:0061134","peptidase regulator activity","15/454","219/17697",0.00055220337247745,0.0155307198509283,0.0134660120656782,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/RARRES1/TNFSF14/PCOLCE2/SPOCK3/WFDC2/SERPINA12",15,-0.258198889747161]
["MF","GO:1901681","sulfur compound binding","15/454","250/17697",0.0020883139935323,0.0469870648544767,0.0407404414176828,"SAA1/SERPINA5/ACADVL/FST/GSTM1/HADHA/LIPC/SOD3/THBS4/COL5A3/CHRD/GREM2/PCOLCE2/CXCL13/SOAT2",15,0.258198889747161]
["BP","GO:0006695","cholesterol biosynthetic process","14/463","75/18670",3.85409975372273e-09,9.86167774483803e-07,8.33956190131187e-07,"APOA4/FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/NPC1L1/HMGCR/ACAT2/ELOVL6/MVK",14,0.534522483824849]
["BP","GO:0006721","terpenoid metabolic process","14/463","120/18670",1.66478351919331e-06,0.000174759582758396,0.000147786045738915,"APOA4/SDC1/CYP3A5/CYP3A7/CYP2D6/SDC4/CYP1B1/HMGCS1/DGAT2/LSS/FDFT1/RDH10/RDH11/UGT1A9",14,-0.534522483824849]
["BP","GO:0015718","monocarboxylic acid transport","14/463","162/18670",5.33229934269935e-05,0.00204115243711116,0.0017261076197924,"PLA2G2A/ACSL4/PLIN2/CPT1A/RXRA/SLC22A9/CEACAM1/SLC16A14/NR1H4/CROT/SLC6A11/SLC27A4/SLC16A13/SLC16A9",14,-0.534522483824849]
["BP","GO:0050796","regulation of insulin secretion","14/463","176/18670",0.00013030110206115,0.00379765091697094,0.00321149663587726,"CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC25A4/NR1H4/ENHO",14,-2.67261241912424]
["BP","GO:0090276","regulation of peptide hormone secretion","14/463","208/18670",0.000717654825015441,0.0136654830400615,0.0115562630084494,"CPT1A/SREBF1/SYT7/LRP5/NR0B2/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC25A4/NR1H4/ENHO",14,-2.67261241912424]
["BP","GO:0015893","drug transport","14/463","214/18670",0.000946707293615219,0.016999209035354,0.014375439929365,"AGT/SYT7/SLC22A18/SYT8/HBB/AMN/SLC25A18/SYT12/SLC1A7/CYGB/SFXN5/CHRNA4/SLC25A4/SLC44A4",14,-1.0690449676497]
["BP","GO:0032869","cellular response to insulin stimulus","14/463","216/18670",0.00103557229409428,0.0181357946644326,0.0153365974986036,"AHSG/AGT/ERRFI1/SREBF1/GCK/BAIAP2/CEACAM1/SYAP1/CISH/PID1/NR1H4/SLC25A33/ENHO/SERPINA12",14,-1.60356745147455]
["BP","GO:0045444","fat cell differentiation","14/463","223/18670",0.00140377838405244,0.0229882748172427,0.0194401141269409,"ATF5/CCND1/SREBF1/ANGPTL8/LRP5/LAMB3/PPARGC1A/FNDC5/BNIP3/NR4A1/SYAP1/NR1D1/HES1/DUSP10",14,-2.1380899352994]
["BP","GO:0031669","cellular response to nutrient levels","14/463","237/18670",0.00247192180233027,0.0351390550650699,0.0297154634790361,"LCN2/SREBF1/HMOX1/JUN/CDKN1A/SLC39A5/COMT/AIFM1/AQP3/ATF3/BAIAP2/PIM1/FES/NR1H4",14,-3.20713490294909]
["BP","GO:0031348","negative regulation of defense response","14/463","239/18670",0.00266847698281242,0.0374135094781988,0.0316388637219541,"SAA1/A2M/TKFC/TSPAN6/TNFRSF1A/NT5E/CEACAM1/CHID1/FNDC4/NR1D1/MVK/NR1H4/DUSP10/HGF",14,-3.20713490294909]
["BP","GO:0033002","muscle cell proliferation","14/463","239/18670",0.00266847698281242,0.0374135094781988,0.0316388637219541,"AGT/SOD2/TGM2/IGFBP3/HMOX1/JUN/CDKN1A/HPGD/RXRA/TRIB1/COMT/PPARGC1A/HMGCR/PIM1",14,-3.74165738677394]
["MF","GO:0020037","heme binding","14/454","135/17697",9.86118266288001e-06,0.001109383049574,0.000961897817642331,"CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/HMOX1/CYP7A1/HBB/CYP4F22/CYGB/NR1D1/STC2/CYP2D7",14,-1.0690449676497]
["MF","GO:0046906","tetrapyrrole binding","14/454","145/17697",2.2331797472903e-05,0.00215342332774422,0.0018671397586367,"CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/HMOX1/CYP7A1/HBB/CYP4F22/CYGB/NR1D1/STC2/CYP2D7",14,-1.0690449676497]
["MF","GO:0004866","endopeptidase inhibitor activity","14/454","175/17697",0.000173498485622392,0.00688891045853614,0.00597307479913621,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/RARRES1/TNFSF14/SPOCK3/WFDC2/SERPINA12",14,-0.534522483824849]
["MF","GO:0030414","peptidase inhibitor activity","14/454","182/17697",0.00026089587172689,0.00926866912713951,0.00803646009308315,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/RARRES1/TNFSF14/SPOCK3/WFDC2/SERPINA12",14,-0.534522483824849]
["MF","GO:0061135","endopeptidase regulator activity","14/454","182/17697",0.00026089587172689,0.00926866912713951,0.00803646009308315,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/RARRES1/TNFSF14/SPOCK3/WFDC2/SERPINA12",14,-0.534522483824849]
["KEGG","hsa04976","Bile secretion","14/268","90/8076",1.31900262601825e-06,0.000216259782021574,0.000174174388966617,"UGT2B4/SLC22A7/SCARB1/CYP7A1/RXRA/PRKACA/UGT2B17/UGT2B11/NR0B2/HMGCR/UGT1A9/ADCY1/ABCG5/NR1H4",14,-2.1380899352994]
["BP","GO:0042632","cholesterol homeostasis","13/463","96/18670",7.04307860314075e-07,9.01073868789319e-05,7.6199623439901e-05,"APOA4/G6PC/SCARB1/DGAT2/CYP7A1/LRP5/LIPC/ACSM1/COMMD9/ABCG5/NR1D1/NR1H4/SOAT2",13,-0.277350098112615]
["BP","GO:0055092","sterol homeostasis","13/463","97/18670",7.95217691202878e-07,9.86551887207449e-05,8.34281016384774e-05,"APOA4/G6PC/SCARB1/DGAT2/CYP7A1/LRP5/LIPC/ACSM1/COMMD9/ABCG5/NR1D1/NR1H4/SOAT2",13,-0.277350098112615]
["BP","GO:0097006","regulation of plasma lipoprotein particle levels","13/463","101/18670",1.27257559749907e-06,0.000137103276214768,0.000115941859838627,"APOA4/AGT/PLA2G2A/SCARB1/HMOX1/DGAT2/LIPC/FGF21/PRKACA/AMN/AGTR1/NR1H4/SOAT2",13,-0.832050294337844]
["BP","GO:0006641","triglyceride metabolic process","13/463","105/18670",1.98990503912675e-06,0.000203666780754623,0.000172231517728628,"APOA4/G6PC/ACSL4/SCARB1/CPT1A/SREBF1/DGAT2/LIPC/FGF21/PNPLA2/PLIN5/GK/SERPINA12",13,-0.277350098112615]
["BP","GO:0006805","xenobiotic metabolic process","13/463","125/18670",1.39295163078864e-05,0.000851155817380403,0.00071978286153399,"CYP3A5/CYP3A7/GSTA2/CYP2D6/CYP2A7/CYP1B1/GSTM1/PHGDH/BCHE/ACSM1/UGT2B11/UGT1A9/CYP2D7",13,-1.9414506867883]
["BP","GO:0006639","acylglycerol metabolic process","13/463","129/18670",1.95805629473998e-05,0.00109812088639253,0.000928629726517632,"APOA4/G6PC/ACSL4/SCARB1/CPT1A/SREBF1/DGAT2/LIPC/FGF21/PNPLA2/PLIN5/GK/SERPINA12",13,-0.277350098112615]
["BP","GO:0006638","neutral lipid metabolic process","13/463","130/18670",2.12739976886842e-05,0.00112466919913883,0.000951080399035203,"APOA4/G6PC/ACSL4/SCARB1/CPT1A/SREBF1/DGAT2/LIPC/FGF21/PNPLA2/PLIN5/GK/SERPINA12",13,-0.277350098112615]
["BP","GO:0007586","digestion","13/463","139/18670",4.32738722982827e-05,0.00184545034572051,0.0015606114691782,"APOA4/MUC13/SCARB1/ALPI/SST/PPARGC1A/SGK1/NPC1L1/ABCG5/VSIG1/TFF2/SLC2A5/SOAT2",13,0.832050294337844]
["BP","GO:0033865","nucleoside bisphosphate metabolic process","13/463","140/18670",4.66474930752473e-05,0.0018908399668323,0.00159899535929639,"FASN/ACSL4/HMGCS1/DGAT2/ACSS2/ACSM1/HMGCR/SUCLG1/ELOVL6/KYNU/ACSF2/MVK/CROT",13,-0.832050294337844]
["BP","GO:0033875","ribonucleoside bisphosphate metabolic process","13/463","140/18670",4.66474930752473e-05,0.0018908399668323,0.00159899535929639,"FASN/ACSL4/HMGCS1/DGAT2/ACSS2/ACSM1/HMGCR/SUCLG1/ELOVL6/KYNU/ACSF2/MVK/CROT",13,-0.832050294337844]
["BP","GO:0034032","purine nucleoside bisphosphate metabolic process","13/463","140/18670",4.66474930752473e-05,0.0018908399668323,0.00159899535929639,"FASN/ACSL4/HMGCS1/DGAT2/ACSS2/ACSM1/HMGCR/SUCLG1/ELOVL6/KYNU/ACSF2/MVK/CROT",13,-0.832050294337844]
["BP","GO:0034620","cellular response to unfolded protein","13/463","140/18670",4.66474930752473e-05,0.0018908399668323,0.00159899535929639,"CCND1/CREB3L3/ACADVL/AGR2/HSPA1A/HSPA1B/HSPA6/FGF21/HERPUD1/ATF3/BAG3/STC2/PDIA5",13,0.277350098112615]
["BP","GO:0042542","response to hydrogen peroxide","13/463","146/18670",7.21124441974348e-05,0.00248091047516217,0.0020979905260094,"LCN2/SDC1/TXNIP/CYP1B1/HMOX1/JUN/MET/SIGMAR1/PPIF/AIFM1/BNIP3/HBB/HGF",13,-1.9414506867883]
["BP","GO:0051592","response to calcium ion","13/463","148/18670",8.29326512291726e-05,0.00276037621245717,0.00233432169356225,"SDC1/TXNIP/CCND1/FOS/SYT7/JUN/FOSB/PPIF/SYT8/AQP3/SYT12/ADCY1/ADGRV1",13,-2.49615088301353]
["BP","GO:0016999","antibiotic metabolic process","13/463","151/18670",0.000101791879297872,0.00320566118342685,0.00271087846972229,"APOA4/IDH2/ALDH1B1/FH/ACSS2/AKR1A1/SDHA/ACSM1/SUCLG1/HBB/FAHD1/NPL/ESD",13,-1.38675049056307]
["BP","GO:0001678","cellular glucose homeostasis","13/463","152/18670",0.000108851646883983,0.00335066648378216,0.00283350270361236,"CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/KLF15/GCK/HMGCR/SYBU/PIM3/NR1D1/NADK/NR1H4",13,-1.38675049056307]
["BP","GO:0062013","positive regulation of small molecule metabolic process","13/463","153/18670",0.000116330275351022,0.00352782331323766,0.00298331598931393,"APOA4/CPT1A/SREBF1/DGAT2/CYP7A1/COMT/PPARGC1A/RDH10/GCK/PLIN5/NR1D1/PID1/NR1H4",13,-0.832050294337844]
["BP","GO:0035967","cellular response to topologically incorrect protein","13/463","161/18670",0.00019384961551348,0.00494765407126106,0.00418400078172875,"CCND1/CREB3L3/ACADVL/AGR2/HSPA1A/HSPA1B/HSPA6/FGF21/HERPUD1/ATF3/BAG3/STC2/PDIA5",13,0.277350098112615]
["BP","GO:0034614","cellular response to reactive oxygen species","13/463","168/18670",0.000294549193327493,0.00681290620046755,0.00576135769761596,"APOA4/SOD2/LCN2/CYP1B1/FOS/JUN/MET/SIGMAR1/SOD3/PPIF/AIFM1/BNIP3/HGF",13,-0.832050294337844]
["BP","GO:1901136","carbohydrate derivative catabolic process","13/463","192/18670",0.00104101410506636,0.0181357946644326,0.0153365974986036,"SDC1/SDC4/FUCA1/GUSB/FBXO2/NT5E/NEU4/NAGA/GALT/NPL/UPP2/PGM2/NUDT16",13,-1.9414506867883]
["BP","GO:0045333","cellular respiration","13/463","193/18670",0.00109167016591,0.0185448035652926,0.0156824772905786,"COX3/ND2/IDH2/FH/SHMT2/SDHA/PPARGC1A/UQCRC2/BNIP3/SUCLG1/SLC25A18/FAHD1/NDUFA5",13,-3.05085107923876]
["BP","GO:1901605","alpha-amino acid metabolic process","13/463","222/18670",0.00374256726319019,0.048334606862778,0.0408743275066662,"SEPHS2/OAT/COMT/SHMT2/PHGDH/PSAT1/P4HA1/GCAT/KYNU/PRODH/NR1H4/CTPS1/NIT2",13,-2.49615088301353]
["CC","GO:0098858","actin-based cell projection","13/473","208/19717",0.00160136153365352,0.0404637210815983,0.0365565321002422,"SCARB1/CDHR5/ESPN/CDHR2/BAIAP2/CEACAM1/HOMER2/PTPRH/ENPP7/MAP2/MPP1/SLC27A4/ADGRV1",13,-0.832050294337844]
["MF","GO:0005506","iron ion binding","13/454","152/17697",0.000151505317086037,0.00681773926887168,0.00591136535437451,"LCN2/CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/CYP7A1/P4HA1/CYP4F22/CYGB/ALOX15B/CYP2D7",13,-0.277350098112615]
["KEGG","hsa04934","Cushing syndrome","13/268","155/8076",0.00188338813440079,0.0278543192508748,0.0224337090801202,"AGT/CCND1/CREB3L3/SCARB1/CYP17A1/CDKN1A/FH/PRKACA/RASD1/NR4A1/ADCY1/CCNE1/AGTR1",13,-1.38675049056307]
["BP","GO:0019395","fatty acid oxidation","12/463","99/18670",6.15546569329182e-06,0.000466675491635865,0.000394645743961731,"ACADVL/CPT1A/DGAT2/HADHA/HADHB/PPARGC1A/ACSM1/ACAT2/CYGB/PLIN5/CROT/ECHDC1",12,-2.3094010767585]
["BP","GO:0034440","lipid oxidation","12/463","101/18670",7.59090473633737e-06,0.000535813172251124,0.000453112262755238,"ACADVL/CPT1A/DGAT2/HADHA/HADHB/PPARGC1A/ACSM1/ACAT2/CYGB/PLIN5/CROT/ECHDC1",12,-2.3094010767585]
["BP","GO:0062014","negative regulation of small molecule metabolic process","12/463","107/18670",1.38044693556405e-05,0.000851155817380403,0.00071978286153399,"FGF19/ACADVL/DGAT2/CYP7A1/PPARGC1A/PPIF/GCK/CEACAM1/PLIN5/PID1/NR1H4/SERPINA12",12,-0.577350269189626]
["BP","GO:0071331","cellular response to hexose stimulus","12/463","135/18670",0.000137972608976553,0.0038955852493104,0.00329431514282311,"CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",12,-1.73205080756888]
["BP","GO:0071326","cellular response to monosaccharide stimulus","12/463","136/18670",0.000147996319644851,0.00414997899058917,0.00350944409020847,"CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",12,-1.73205080756888]
["BP","GO:0042737","drug catabolic process","12/463","140/18670",0.000194570665723749,0.00494765407126106,0.00418400078172875,"APOA4/CYP3A5/CYP2D6/CYP2A7/ALDH1B1/COMT/GCAT/HBB/CPN1/NT5E/NPL/CYP2D7",12,-2.3094010767585]
["BP","GO:0071322","cellular response to carbohydrate stimulus","12/463","144/18670",0.000253108945443595,0.0059553334634832,0.00503614834581962,"CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/HMGCR/SYBU/PIM3/NR1D1/NADK/SLC2A5/NR1H4",12,-1.73205080756888]
["BP","GO:0006633","fatty acid biosynthetic process","12/463","164/18670",0.000820417575058772,0.0151296826679757,0.0127944684891811,"APOA4/FASN/CYP2D6/ACADVL/CYP7A1/HPGD/ACSS2/LIPC/ACSM1/ELOVL6/CEACAM1/ALOX15B",12,-0.577350269189626]
["BP","GO:1901568","fatty acid derivative metabolic process","12/463","167/18670",0.000961534050949482,0.0171900454348785,0.0145368213908198,"FASN/ACSL4/CYP2D6/CYP2A7/CYP1B1/DGAT2/HPGD/TNFRSF1A/ELOVL6/CYP4F22/ALOX15B/CYP2D7",12,-0.577350269189626]
["BP","GO:0048660","regulation of smooth muscle cell proliferation","12/463","169/18670",0.00106640357199859,0.0183439337132866,0.0155126110053222,"AGT/SOD2/TGM2/IGFBP3/HMOX1/JUN/CDKN1A/HPGD/TRIB1/COMT/PPARGC1A/HMGCR",12,-3.46410161513775]
["BP","GO:0048659","smooth muscle cell proliferation","12/463","171/18670",0.00118060454293148,0.0199727066064524,0.0168899884371538,"AGT/SOD2/TGM2/IGFBP3/HMOX1/JUN/CDKN1A/HPGD/TRIB1/COMT/PPARGC1A/HMGCR",12,-3.46410161513775]
["BP","GO:0072524","pyridine-containing compound metabolic process","12/463","195/18670",0.00353320312097324,0.0465110404413648,0.0393322222537857,"IDH2/H6PD/PSAT1/ENO3/PPARGC1A/ALDOC/GCK/KYNU/NT5E/KCNAB2/PGM2/NADK",12,-1.73205080756888]
["BP","GO:0002685","regulation of leukocyte migration","12/463","196/18670",0.0036817064918509,0.0478504964369447,0.0404649378502844,"LBP/SERPINE1/HMOX1/CCL25/CCL20/THBS4/CD99L2/CD9/TNFSF14/MPP1/CXCL13/IL33",12,1.15470053837925]
["CC","GO:0072562","blood microparticle","12/473","147/19717",0.00022738636568202,0.00962602281387217,0.00869653117871584,"A2M/AHSG/APOA4/AGT/ITIH2/HSPA1A/ANGPTL4/HSPA1B/BCHE/HSPA6/ACSM1/HBB",12,-0.577350269189626]
["MF","GO:0016705","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen","12/454","159/17697",0.000835175624998411,0.0225497418749571,0.0195519009473312,"CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/HMOX1/CYP7A1/P4HA1/CYP4F22/KDM4B/CYP2D7",12,-1.15470053837925]
["BP","GO:0045540","regulation of cholesterol biosynthetic process","11/463","50/18670",3.02645929074602e-08,6.05483294116422e-06,5.12029042333816e-06,"FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/HMGCR/ELOVL6/MVK",11,0.904534033733291]
["BP","GO:0106118","regulation of sterol biosynthetic process","11/463","50/18670",3.02645929074602e-08,6.05483294116422e-06,5.12029042333816e-06,"FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/HMGCR/ELOVL6/MVK",11,0.904534033733291]
["BP","GO:1902930","regulation of alcohol biosynthetic process","11/463","81/18670",4.92015575930289e-06,0.000394963091736981,0.000334001904898807,"FASN/HMGCS1/DHCR7/SREBF1/CYP7A1/IDI1/LSS/FDFT1/HMGCR/ELOVL6/MVK",11,0.904534033733291]
["BP","GO:0046889","positive regulation of lipid biosynthetic process","11/463","84/18670",7.05098410065064e-06,0.000506433840492346,0.000428267529215881,"APOA4/SCARB1/SREBF1/DGAT2/CYP7A1/PPARGC1A/RDH10/TNFRSF1A/PLIN5/NR1D1/NR1H4",11,-0.301511344577764]
["BP","GO:0046364","monosaccharide biosynthetic process","11/463","98/18670",3.11631878826068e-05,0.00151883441894514,0.00128440758077561,"G6PC/DGAT2/AKR1A1/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/NR1D1/SERPINA12",11,-2.11057941204435]
["BP","GO:0001523","retinoid metabolic process","11/463","104/18670",5.43050258505088e-05,0.00205856273918503,0.00174083070197196,"APOA4/SDC1/CYP3A5/CYP3A7/CYP2D6/SDC4/CYP1B1/DGAT2/RDH10/RDH11/UGT1A9",11,-1.50755672288882]
["BP","GO:0006637","acyl-CoA metabolic process","11/463","105/18670",5.93298836139023e-05,0.00220815039559378,0.00186733002111124,"FASN/ACSL4/HMGCS1/DGAT2/ACSS2/ACSM1/SUCLG1/ELOVL6/KYNU/ACSF2/MVK",11,-0.301511344577764]
["BP","GO:0035383","thioester metabolic process","11/463","105/18670",5.93298836139023e-05,0.00220815039559378,0.00186733002111124,"FASN/ACSL4/HMGCS1/DGAT2/ACSS2/ACSM1/SUCLG1/ELOVL6/KYNU/ACSF2/MVK",11,-0.301511344577764]
["BP","GO:0046916","cellular transition metal ion homeostasis","11/463","108/18670",7.68681173123322e-05,0.00260081051468337,0.00219938440922367,"MT1G/LCN2/MT1B/MT1M/HMOX1/MT1F/MT1H/SLC39A5/NDFIP1/MT1A/SLC22A17",11,-1.50755672288882]
["BP","GO:0016101","diterpenoid metabolic process","11/463","110/18670",9.08788967560177e-05,0.00295284288348521,0.0024970817997539,"APOA4/SDC1/CYP3A5/CYP3A7/CYP2D6/SDC4/CYP1B1/DGAT2/RDH10/RDH11/UGT1A9",11,-1.50755672288882]
["BP","GO:1990748","cellular detoxification","11/463","112/18670",0.00010701588557389,0.00332718811362217,0.00281364813866333,"APOA4/SOD2/GSTM1/GSTK1/PRXL2A/AKR1A1/SOD3/RDH11/HBB/CYGB/ESD",11,-0.904534033733291]
["BP","GO:0055076","transition metal ion homeostasis","11/463","131/18670",0.000425111631580166,0.0092085027496783,0.00778720220700175,"MT1G/LCN2/MT1B/MT1M/HMOX1/MT1F/MT1H/SLC39A5/NDFIP1/MT1A/SLC22A17",11,-1.50755672288882]
["BP","GO:0072329","monocarboxylic acid catabolic process","11/463","132/18670",0.000453638931095129,0.00977472517843925,0.00826603016272509,"ACADVL/CPT1A/HADHA/AKR1A1/HADHB/ACAT2/PLIN5/CROT/SLC27A4/ECHDC1/XYLB",11,-2.71360210119987]
["BP","GO:0071333","cellular response to glucose stimulus","11/463","133/18670",0.000483751957926877,0.0102852644495808,0.00869776946357221,"CYP7A1/LRP5/FGF21/PPARGC1A/PRKACA/HMGCR/SYBU/PIM3/NR1D1/NADK/NR1H4",11,-2.11057941204435]
["BP","GO:0042133","neurotransmitter metabolic process","11/463","153/18670",0.00153946568782838,0.0246194239295679,0.0208195010167251,"AGT/CYP1B1/COMT/SHMT2/PHGDH/BCHE/GCAT/HBB/CHDH/DDC/SLC44A4",11,-2.11057941204435]
["CC","GO:0005811","lipid droplet","11/473","81/19717",3.60142293394564e-06,0.00106050909933662,0.000958106024265992,"ACSL4/PLIN2/G0S2/DGAT2/SCCPDH/SIGMAR1/LSS/HSD17B11/RDH10/PNPLA2/PLIN5",11,-0.301511344577764]
["CC","GO:0098862","cluster of actin-based cell projections","11/473","150/19717",0.00100891353616146,0.0295689274828859,0.0267137430222509,"CDHR5/ESPN/CDHR2/NPC1L1/AMN/HOMER2/SLC3A1/MPP1/SLC27A4/ADGRV1/SOAT2",11,-2.11057941204435]
["CC","GO:0042581","specific granule","11/473","160/19717",0.00169926387744245,0.0404637210815983,0.0365565321002422,"CHI3L1/LYZ/LCN2/SLPI/OLFM4/TOLLIP/CEACAM1/KCNAB2/SLC2A5/NIT2/CRISP3",11,1.50755672288882]
["KEGG","hsa00140","Steroid hormone biosynthesis","11/268","61/8076",4.19071423318214e-06,0.000392530233174727,0.000316141600047074,"UGT2B4/CYP3A5/CYP3A7/CYP17A1/CYP1B1/CYP7A1/HSD17B2/COMT/UGT2B17/UGT2B11/UGT1A9",11,-0.904534033733291]
["KEGG","hsa00980","Metabolism of xenobiotics by cytochrome P450","11/268","77/8076",4.18225161410877e-05,0.00221422824574507,0.00178332673847234,"UGT2B4/CYP3A5/GSTA2/CYP2D6/CYP1B1/GSTM1/GSTK1/UGT2B17/UGT2B11/UGT1A9/CYP2D7",11,-1.50755672288882]
["KEGG","hsa03320","PPAR signaling pathway","11/268","78/8076",4.7278894926941e-05,0.00221422824574507,0.00178332673847234,"ACSL4/PLIN2/CPT1A/HMGCS1/ANGPTL4/CYP7A1/RXRA/MMP1/PLIN5/GK/SLC27A4",11,-0.301511344577764]
["KEGG","hsa04068","FoxO signaling pathway","11/268","131/8076",0.00409624087026752,0.0426312475757471,0.034334962460332,"SOD2/G6PC/CCND1/CDKN1A/TNFSF10/SGK1/BNIP3/HOMER2/ARAF/SGK2/FBXO25",11,-2.71360210119987]
["BP","GO:0046365","monosaccharide catabolic process","10/463","67/18670",5.58823379172374e-06,0.000431664700817302,0.000365038747586482,"TKFC/LRP5/AKR1A1/ENO3/ALDOC/GCK/GALM/GALT/PGM2/XYLB",10,-2.5298221281347]
["BP","GO:0042446","hormone biosynthetic process","10/463","86/18670",5.2454526546238e-05,0.00204115243711116,0.0017261076197924,"SCARB1/CYP17A1/EGR1/DHCR7/HSD17B2/HSD17B11/PPARGC1A/HSD17B14/STC2/SLC44A4",10,0.632455532033676]
["BP","GO:0006094","gluconeogenesis","10/463","89/18670",7.05117297832197e-05,0.00244639848925849,0.00206880534573604,"G6PC/DGAT2/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/NR1D1/SERPINA12",10,-1.89736659610103]
["BP","GO:0019319","hexose biosynthetic process","10/463","92/18670",9.35966856809594e-05,0.0030167222378417,0.00255110159675555,"G6PC/DGAT2/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/NR1D1/SERPINA12",10,-1.89736659610103]
["BP","GO:0043648","dicarboxylic acid metabolic process","10/463","99/18670",0.000173369370299386,0.00454983462824157,0.00384758339348636,"OAT/IDH2/FH/SHMT2/SDHA/SUCLG1/KYNU/PRODH/NR1H4/NIT2",10,-1.89736659610103]
["BP","GO:0022600","digestive system process","10/463","100/18670",0.000188445776010793,0.00488289244929231,0.0041292348920686,"APOA4/MUC13/SCARB1/SGK1/NPC1L1/ABCG5/VSIG1/TFF2/SLC2A5/SOAT2",10,0.632455532033676]
["BP","GO:0001676","long-chain fatty acid metabolic process","10/463","109/18670",0.000380926137571095,0.00842979247143817,0.00712868316626646,"ACSL4/CYP2D6/CYP2A7/CYP1B1/CPT1A/HPGD/ELOVL6/SLC27A4/ALOX15B/CYP2D7",10,-1.26491106406735]
["BP","GO:0030260","entry into host cell","10/463","134/18670",0.00188595730208712,0.0289180119653359,0.0244546168601007,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MET/MRC1/CD55/EPHA2/PVR",10,0]
["BP","GO:0044409","entry into host","10/463","134/18670",0.00188595730208712,0.0289180119653359,0.0244546168601007,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MET/MRC1/CD55/EPHA2/PVR",10,0]
["BP","GO:0051806","entry into cell of other organism involved in symbiotic interaction","10/463","134/18670",0.00188595730208712,0.0289180119653359,0.0244546168601007,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MET/MRC1/CD55/EPHA2/PVR",10,0]
["BP","GO:0051828","entry into other organism involved in symbiotic interaction","10/463","134/18670",0.00188595730208712,0.0289180119653359,0.0244546168601007,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MET/MRC1/CD55/EPHA2/PVR",10,0]
["BP","GO:0001889","liver development","10/463","135/18670",0.0019929129842197,0.0299962711668951,0.0253664504841277,"REG1A/CCND1/HMGCS1/HMOX1/JUN/MET/AK4/CEACAM1/HES1/HGF",10,-1.26491106406735]
["BP","GO:0061008","hepaticobiliary system development","10/463","138/18670",0.00234344608667004,0.0337653556074051,0.0285537897803603,"REG1A/CCND1/HMGCS1/HMOX1/JUN/MET/AK4/CEACAM1/HES1/HGF",10,-1.26491106406735]
["BP","GO:0007612","learning","10/463","145/18670",0.00335543663824004,0.0444105619308393,0.0375559453347724,"AGT/RELN/FOS/JUN/GPR88/COMT/BCHE/HMGCR/CLDN5/C1QL1",10,-0.632455532033676]
["BP","GO:0071236","cellular response to antibiotic","10/463","147/18670",0.00370067062801151,0.0479447644021491,0.0405446558811788,"LCN2/CYP1B1/EGR1/MET/SIGMAR1/PPIF/AIFM1/BNIP3/ADCY1/HGF",10,-1.26491106406735]
["MF","GO:0004867","serine-type endopeptidase inhibitor activity","10/454","94/17697",0.000147616521423218,0.00681773926887168,0.00591136535437451,"A2M/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/WFDC2/SERPINA12",10,-1.26491106406735]
["KEGG","hsa00982","Drug metabolism - cytochrome P450","10/268","71/8076",0.000105796991330073,0.00330321717375007,0.00266039217964512,"UGT2B4/CYP3A5/GSTA2/CYP2D6/GSTM1/GSTK1/UGT2B17/UGT2B11/UGT1A9/CYP2D7",10,-1.89736659610103]
["KEGG","hsa05204","Chemical carcinogenesis","10/268","82/8076",0.000355682544518922,0.00832889958415143,0.00670804798873406,"UGT2B4/CYP3A5/CYP3A7/GSTA2/CYP1B1/GSTM1/GSTK1/UGT2B17/UGT2B11/UGT1A9",10,-1.26491106406735]
["BP","GO:0008210","estrogen metabolic process","9/463","32/18670",5.54641761363288e-08,1.03213789591877e-05,8.72830982355912e-06,"CYP3A5/CYP3A7/CYP2D6/CYP1B1/HSD17B2/COMT/HSD17B11/UGT2B11/HSD17B14",9,-1]
["BP","GO:0071276","cellular response to cadmium ion","9/463","37/18670",2.20335510681662e-07,3.34093918789157e-05,2.82527678219098e-05,"MT1G/MT1B/FOS/MT1M/HMOX1/MT1F/MT1H/JUN/MT1A",9,-2.33333333333333]
["BP","GO:0046686","response to cadmium ion","9/463","63/18670",2.36817798974159e-05,0.00121191508625026,0.00102486018529738,"MT1G/MT1B/FOS/MT1M/HMOX1/MT1F/MT1H/JUN/MT1A",9,-2.33333333333333]
["BP","GO:0006081","cellular aldehyde metabolic process","9/463","74/18670",8.69422685456556e-05,0.00284753317940731,0.00240802628418241,"CYP1B1/TKFC/IDH2/H6PD/AKR1A1/RDH10/RDH11/ESD/PGM2",9,-1]
["BP","GO:0071277","cellular response to calcium ion","9/463","83/18670",0.000212463074265808,0.00528868228467327,0.00447239247018496,"FOS/SYT7/JUN/FOSB/PPIF/SYT8/SYT12/ADCY1/ADGRV1",9,-1.66666666666667]
["BP","GO:0009060","aerobic respiration","9/463","87/18670",0.000303877048423484,0.00695012645947344,0.0058773984843566,"COX3/IDH2/FH/SHMT2/SDHA/UQCRC2/BNIP3/SUCLG1/FAHD1",9,-2.33333333333333]
["BP","GO:0045833","negative regulation of lipid metabolic process","9/463","92/18670",0.000461637808762419,0.0098950009899128,0.00836774181879084,"FGF19/ACADVL/DGAT2/CYP7A1/CEACAM1/PLIN5/NR1H4/ENHO/SERPINA12",9,0.333333333333333]
["BP","GO:0019217","regulation of fatty acid metabolic process","9/463","96/18670",0.000631594283045195,0.0126752303666031,0.0107188524093687,"APOA4/ACADVL/CPT1A/SREBF1/DGAT2/CYP7A1/PPARGC1A/CEACAM1/PLIN5",9,-1]
["BP","GO:0015748","organophosphate ester transport","9/463","105/18670",0.00120422412066916,0.0202884508231257,0.0171569986262979,"APOA4/G6PC/SCARB1/GJB1/SLC37A4/SLC25A4/SLC25A33/CPTP/SLC44A4",9,-0.333333333333333]
["BP","GO:0009062","fatty acid catabolic process","9/463","108/18670",0.00146882308555005,0.0236746524104012,0.0200205517131128,"ACADVL/CPT1A/HADHA/HADHB/ACAT2/PLIN5/CROT/SLC27A4/ECHDC1",9,-2.33333333333333]
["BP","GO:0030968","endoplasmic reticulum unfolded protein response","9/463","121/18670",0.00320329441045229,0.043424792438383,0.0367223259532156,"CCND1/CREB3L3/ACADVL/AGR2/FGF21/HERPUD1/ATF3/STC2/PDIA5",9,-1]
["BP","GO:0043618","regulation of transcription from RNA polymerase II promoter in response to stress","9/463","121/18670",0.00320329441045229,0.043424792438383,0.0367223259532156,"CREB3L3/UBB/EGR1/HSPA1A/HMOX1/JUN/DNAJB1/ATF3/BAG3",9,-1]
["BP","GO:0046718","viral entry into host cell","9/463","121/18670",0.00320329441045229,0.043424792438383,0.0367223259532156,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MRC1/CD55/EPHA2/PVR",9,-0.333333333333333]
["CC","GO:0043202","lysosomal lumen","9/473","95/19717",0.00046191307361011,0.0175988881045452,0.015899534217948,"SDC1/SDC4/FUCA1/CTSF/GUSB/CHID1/NEU4/ACP2/SMPD1",9,-2.33333333333333]
["MF","GO:0001618","virus receptor activity","9/454","74/17697",0.000112149193518446,0.00630839213541258,0.0054697325961628,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MRC1/CD55/EPHA2/PVR",9,-0.333333333333333]
["MF","GO:0104005","hijacked molecular function","9/454","74/17697",0.000112149193518446,0.00630839213541258,0.0054697325961628,"ANPEP/SCARB1/LAMP1/HSPA1A/HSPA1B/MRC1/CD55/EPHA2/PVR",9,-0.333333333333333]
["MF","GO:0004497","monooxygenase activity","9/454","99/17697",0.00100053623225355,0.0259754598758134,0.0225221921106468,"CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/CYP7A1/CYP4F22/CYP2D7",9,-0.333333333333333]
["KEGG","hsa00010","Glycolysis / Gluconeogenesis","9/268","67/8076",0.000337690486938104,0.00832889958415143,0.00670804798873406,"G6PC/ALDH1B1/ACSS2/AKR1A1/ENO3/ALDOC/GCK/GALM/PGM2",9,-2.33333333333333]
["KEGG","hsa04657","IL-17 signaling pathway","9/268","94/8076",0.00386053629304934,0.0417632388908603,0.0336358732404382,"LCN2/MUC5B/FOS/JUN/MUC5AC/FOSB/CCL20/MMP1/IL17RC",9,0.333333333333333]
["KEGG","hsa01522","Endocrine resistance","9/268","98/8076",0.0050931743321194,0.047706066244185,0.0384221923300235,"CYP2D6/CCND1/FOS/JUN/CDKN1A/PRKACA/ADCY1/ARAF/CYP2D7",9,-3]
["BP","GO:0090207","regulation of triglyceride metabolic process","8/463","40/18670",5.15627223885236e-06,0.000405957279728107,0.000343299178007802,"APOA4/SCARB1/SREBF1/DGAT2/FGF21/PNPLA2/PLIN5/SERPINA12",8,0.707106781186547]
["BP","GO:0071827","plasma lipoprotein particle organization","8/463","45/18670",1.29647261711136e-05,0.000816578291454446,0.00069054225711405,"APOA4/AGT/PLA2G2A/SCARB1/LIPC/PRKACA/AGTR1/SOAT2",8,0]
["BP","GO:0071825","protein-lipid complex subunit organization","8/463","49/18670",2.486975485784e-05,0.00124166800473167,0.00105002084374115,"APOA4/AGT/PLA2G2A/SCARB1/LIPC/PRKACA/AGTR1/SOAT2",8,0]
["BP","GO:0019320","hexose catabolic process","8/463","57/18670",7.66259615477408e-05,0.00260081051468337,0.00219938440922367,"TKFC/LRP5/ENO3/ALDOC/GCK/GALM/GALT/PGM2",8,-2.12132034355964]
["BP","GO:0034381","plasma lipoprotein particle clearance","8/463","69/18670",0.000299213830236174,0.00688191809543201,0.00581971784533872,"SCARB1/HMOX1/DGAT2/LIPC/FGF21/AMN/NR1H4/SOAT2",8,-0.707106781186547]
["BP","GO:0006635","fatty acid beta-oxidation","8/463","72/18670",0.000401497469277155,0.00879000341829237,0.0074332967996204,"ACADVL/CPT1A/HADHA/HADHB/ACAT2/PLIN5/CROT/ECHDC1",8,-2.12132034355964]
["BP","GO:0061045","negative regulation of wound healing","8/463","76/18670",0.000580334136274541,0.0119994341106463,0.0101473629676075,"SERPINE1/TFPI/CDKN1A/TSPAN8/HMGCR/CEACAM1/CD9/DUSP10",8,-1.41421356237309]
["BP","GO:1901264","carbohydrate derivative transport","8/463","76/18670",0.000580334136274541,0.0119994341106463,0.0101473629676075,"LBP/G6PC/SCARB1/AGR2/GJB1/SLC35C1/SLC37A4/SLC25A4",8,-1.41421356237309]
["BP","GO:0034308","primary alcohol metabolic process","8/463","85/18670",0.00122078176548108,0.0203995124403247,0.0172509182670989,"CYP2D6/CYP1B1/DGAT2/ALDH1B1/ACSS2/AKR1A1/RDH10/RDH11",8,-1.41421356237309]
["BP","GO:1903035","negative regulation of response to wounding","8/463","90/18670",0.00176654081535949,0.0274989281295884,0.0232545637050925,"SERPINE1/TFPI/CDKN1A/TSPAN8/HMGCR/CEACAM1/CD9/DUSP10",8,-1.41421356237309]
["BP","GO:0033273","response to vitamin","8/463","93/18670",0.00217658330355069,0.0321694297643917,0.0272041895701243,"CCND1/HMGCS1/BCHE/AQP3/KYNU/PIM1/STC2/FES",8,-1.41421356237309]
["BP","GO:0036473","cell death in response to oxidative stress","8/463","93/18670",0.00217658330355069,0.0321694297643917,0.0272041895701243,"SOD2/CYP1B1/VNN1/MET/SIGMAR1/FBXO7/PRODH/HGF",8,-0.707106781186547]
["BP","GO:0070301","cellular response to hydrogen peroxide","8/463","99/18670",0.00321865878103207,0.0434890727707766,0.0367766848386816,"LCN2/CYP1B1/MET/SIGMAR1/PPIF/AIFM1/BNIP3/HGF",8,-0.707106781186547]
["CC","GO:0035580","specific granule lumen","8/473","62/19717",0.000112234502133071,0.00855226906253998,0.00772645941000297,"CHI3L1/LYZ/LCN2/SLPI/OLFM4/TOLLIP/NIT2/CRISP3",8,1.41421356237309]
["CC","GO:0005902","microvillus","8/473","83/19717",0.000845159782940411,0.0268338231083581,0.0242427411422381,"SCARB1/CDHR5/ESPN/CDHR2/CEACAM1/PTPRH/ENPP7/SLC27A4",8,-0.707106781186547]
["MF","GO:0008395","steroid hydroxylase activity","8/454","38/17697",4.38619659074817e-06,0.000740170674688754,0.000641769816962101,"CYP3A5/CYP3A7/CYP2D6/CYP17A1/CYP2A7/CYP1B1/CYP7A1/CYP2D7",8,-0.707106781186547]
["KEGG","hsa04975","Fat digestion and absorption","8/268","43/8076",6.99774408791261e-05,0.00280909441243349,0.00226242853970107,"APOA4/PLA2G2A/SCARB1/DGAT2/NPC1L1/ACAT2/ABCG5/SLC27A4",8,-0.707106781186547]
["KEGG","hsa04979","Cholesterol metabolism","8/268","50/8076",0.000211881335177324,0.00595386551848282,0.00479520916453945,"APOA4/SCARB1/ANGPTL8/ANGPTL4/CYP7A1/LIPC/ABCG5/SOAT2",8,0.707106781186547]
["KEGG","hsa01212","Fatty acid metabolism","8/268","57/8076",0.000533585302232068,0.0109971363243243,0.00885703056650951,"FASN/ACSL4/ACADVL/CPT1A/HADHA/HADHB/ACAT2/ELOVL6",8,-1.41421356237309]
["KEGG","hsa04978","Mineral absorption","8/268","59/8076",0.000676223884800726,0.0118761819768128,0.00956500889685237,"MT1G/MT1B/MT1M/HMOX1/MT1F/MT1H/ATP2B2/MT1A",8,-1.41421356237309]
["KEGG","hsa04927","Cortisol synthesis and secretion","8/268","65/8076",0.00129674104857114,0.0214343667440288,0.0172631161264888,"AGT/CREB3L3/SCARB1/CYP17A1/PRKACA/NR4A1/ADCY1/AGTR1",8,-1.41421356237309]
["KEGG","hsa00830","Retinol metabolism","8/268","68/8076",0.00174338307445325,0.0272161468845202,0.0219197287138859,"UGT2B4/CYP3A5/CYP3A7/UGT2B17/UGT2B11/RDH10/RDH11/UGT1A9",8,-1.41421356237309]
["KEGG","hsa00983","Drug metabolism - other enzymes","8/268","79/8076",0.0045002368167987,0.0451630909114441,0.0363740945718692,"UGT2B4/GSTA2/GSTM1/GUSB/UGT2B17/UGT2B11/UGT1A9/UPP2",8,-1.41421356237309]
["BP","GO:0090208","positive regulation of triglyceride metabolic process","7/463","21/18670",4.74378322729209e-07,6.47368284417794e-05,5.47449229282936e-05,"APOA4/SCARB1/SREBF1/DGAT2/FGF21/PNPLA2/PLIN5",7,0.377964473009227]
["BP","GO:0045940","positive regulation of steroid metabolic process","7/463","30/18670",6.84484658285583e-06,0.000506433840492346,0.000428267529215881,"APOA4/AGT/SREBF1/CYP7A1/PPARGC1A/AGTR1/NR1D1",7,-1.13389341902768]
["BP","GO:0006882","cellular zinc ion homeostasis","7/463","36/18670",2.46797594730439e-05,0.00124166800473167,0.00105002084374115,"MT1G/MT1B/MT1M/MT1F/MT1H/SLC39A5/MT1A",7,-1.88982236504614]
["BP","GO:0055069","zinc ion homeostasis","7/463","38/18670",3.57479485630041e-05,0.0017017686211272,0.00143910652171016,"MT1G/MT1B/MT1M/MT1F/MT1H/SLC39A5/MT1A",7,-1.88982236504614]
["BP","GO:0055090","acylglycerol homeostasis","7/463","39/18670",4.26456309103556e-05,0.00183780224154733,0.00155414382342559,"APOA4/SCARB1/ANGPTL8/DGAT2/ANGPTL4/LIPC/NR1H4",7,-0.377964473009227]
["BP","GO:0070328","triglyceride homeostasis","7/463","39/18670",4.26456309103556e-05,0.00183780224154733,0.00155414382342559,"APOA4/SCARB1/ANGPTL8/DGAT2/ANGPTL4/LIPC/NR1H4",7,-0.377964473009227]
["BP","GO:0046688","response to copper ion","7/463","44/18670",9.54810078160033e-05,0.00303022671316835,0.00256252170303415,"MT1G/MT1B/MT1M/MT1F/MT1H/SOD3/MT1A",7,-1.13389341902768]
["BP","GO:0051055","negative regulation of lipid biosynthetic process","7/463","57/18670",0.000499415446716427,0.01048516327619,0.00886681459784254,"FGF19/ACADVL/CYP7A1/CEACAM1/NR1H4/ENHO/SERPINA12",7,0.377964473009227]
["BP","GO:0061178","regulation of insulin secretion involved in cellular response to glucose stimulus","7/463","57/18670",0.000499415446716427,0.01048516327619,0.00886681459784254,"LRP5/HMGCR/SYBU/PIM3/NR1D1/NADK/NR1H4",7,-2.64575131106459]
["BP","GO:0007588","excretion","7/463","63/18670",0.000920145001528824,0.0165950380451939,0.01403365133331,"AGT/HMOX1/COMT/SLC22A18/AMN/ABCG5/AGTR1",7,-1.88982236504614]
["BP","GO:0035773","insulin secretion involved in cellular response to glucose stimulus","7/463","64/18670",0.00101147817143609,0.0178491018700833,0.0150941547452508,"LRP5/HMGCR/SYBU/PIM3/NR1D1/NADK/NR1H4",7,-2.64575131106459]
["BP","GO:0046626","regulation of insulin receptor signaling pathway","7/463","66/18670",0.00121544424730364,0.0203935604445128,0.0172458849412497,"AHSG/AGT/CISH/PID1/NR1H4/ENHO/SERPINA12",7,-1.13389341902768]
["BP","GO:0048662","negative regulation of smooth muscle cell proliferation","7/463","67/18670",0.00132881567619863,0.0219361749127307,0.0185504022029597,"SOD2/IGFBP3/HMOX1/CDKN1A/TRIB1/COMT/PPARGC1A",7,-2.64575131106459]
["BP","GO:1900076","regulation of cellular response to insulin stimulus","7/463","74/18670",0.0023715911850077,0.0339485815084669,0.0287087353974617,"AHSG/AGT/CISH/PID1/NR1H4/ENHO/SERPINA12",7,-1.13389341902768]
["MF","GO:0019825","oxygen binding","7/454","36/17697",3.05974966794944e-05,0.00229481225096208,0.00198973194781273,"CYP3A5/CYP3A7/CYP17A1/CYP2A7/CYP1B1/HBB/CYGB",7,-1.13389341902768]
["MF","GO:0016830","carbon-carbon lyase activity","7/454","51/17697",0.00030469774026495,0.0101760857355911,0.00882324158906612,"CYP17A1/SHMT2/ALDOC/FAHD1/DDC/NPL/ECHDC1",7,-1.13389341902768]
["KEGG","hsa00053","Ascorbate and aldarate metabolism","7/268","30/8076",4.33036570225888e-05,0.00221422824574507,0.00178332673847234,"UGT2B4/ALDH1B1/AKR1A1/GUSB/UGT2B17/UGT2B11/UGT1A9",7,-1.88982236504614]
["KEGG","hsa00040","Pentose and glucuronate interconversions","7/268","34/8076",0.000102126999979583,0.00330321717375007,0.00266039217964512,"UGT2B4/AKR1A1/GUSB/UGT2B17/UGT2B11/UGT1A9/XYLB",7,-1.88982236504614]
["KEGG","hsa00071","Fatty acid degradation","7/268","44/8076",0.000547900030393379,0.0109971363243243,0.00885703056650951,"ACSL4/ACADVL/CPT1A/ALDH1B1/HADHA/HADHB/ACAT2",7,-1.88982236504614]
["KEGG","hsa00480","Glutathione metabolism","7/268","57/8076",0.00262009038759076,0.0334656999505911,0.0269530829345461,"ANPEP/GSTA2/IDH2/GSTM1/GSTK1/NAT8/CHAC1",7,-1.13389341902768]
["KEGG","hsa00561","Glycerolipid metabolism","7/268","61/8076",0.00386421427459918,0.0417632388908603,0.0336358732404382,"TKFC/DGAT2/ALDH1B1/LIPC/AKR1A1/PNPLA2/GK",7,-2.64575131106459]
["BP","GO:0010273","detoxification of copper ion","6/463","15/18670",9.32128720336016e-07,0.000109032428030161,9.22036499604558e-05,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:1990169","stress response to copper ion","6/463","15/18670",9.32128720336016e-07,0.000109032428030161,9.22036499604558e-05,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0061687","detoxification of inorganic compound","6/463","17/18670",2.20953342555527e-06,0.000205587041914165,0.000173855393221322,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0097501","stress response to metal ion","6/463","17/18670",2.20953342555527e-06,0.000205587041914165,0.000173855393221322,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0071294","cellular response to zinc ion","6/463","23/18670",1.58801019590119e-05,0.000928759106002781,0.000785408351025415,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0006063","uronic acid metabolic process","6/463","24/18670",2.0732223579503e-05,0.00111966729567942,0.000946850522070709,"UGT2B4/AKR1A1/UGT2B17/UGT2B11/UGT1A9/XYLB",6,-1.63299316185545]
["BP","GO:0019585","glucuronate metabolic process","6/463","24/18670",2.0732223579503e-05,0.00111966729567942,0.000946850522070709,"UGT2B4/AKR1A1/UGT2B17/UGT2B11/UGT1A9/XYLB",6,-1.63299316185545]
["BP","GO:0034368","protein-lipid complex remodeling","6/463","28/18670",5.33471692161441e-05,0.00204115243711116,0.0017261076197924,"APOA4/AGT/PLA2G2A/SCARB1/LIPC/AGTR1",6,0]
["BP","GO:0034369","plasma lipoprotein particle remodeling","6/463","28/18670",5.33471692161441e-05,0.00204115243711116,0.0017261076197924,"APOA4/AGT/PLA2G2A/SCARB1/LIPC/AGTR1",6,0]
["BP","GO:0008299","isoprenoid biosynthetic process","6/463","29/18670",6.58651570792523e-05,0.00232458580243499,0.0019657940257138,"HMGCS1/IDI1/LSS/RDH10/HMGCR/MVK",6,0.816496580927726]
["BP","GO:0034367","protein-containing complex remodeling","6/463","29/18670",6.58651570792523e-05,0.00232458580243499,0.0019657940257138,"APOA4/AGT/PLA2G2A/SCARB1/LIPC/AGTR1",6,0]
["BP","GO:0071280","cellular response to copper ion","6/463","29/18670",6.58651570792523e-05,0.00232458580243499,0.0019657940257138,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0006739","NADP metabolic process","6/463","32/18670",0.000117980828999217,0.00355156995531466,0.00300339741933765,"IDH2/H6PD/GCK/KCNAB2/PGM2/NADK",6,0]
["BP","GO:0046466","membrane lipid catabolic process","6/463","35/18670",0.000198443807370477,0.00501499350231316,0.00424094660455815,"CYP1B1/FUCA1/NEU4/NAGA/SMPD1/ENPP7",6,-0.816496580927726]
["BP","GO:0010742","macrophage derived foam cell differentiation","6/463","36/18670",0.000233196616949963,0.00555062180112297,0.00469390252844816,"CRP/AGT/PLA2G2A/AGTR1/ALOX15B/SOAT2",6,0]
["BP","GO:0090077","foam cell differentiation","6/463","36/18670",0.000233196616949963,0.00555062180112297,0.00469390252844816,"CRP/AGT/PLA2G2A/AGTR1/ALOX15B/SOAT2",6,0]
["BP","GO:0050892","intestinal absorption","6/463","38/18670",0.000316968118138177,0.00716943356716959,0.00606285629867091,"APOA4/SCARB1/NPC1L1/ABCG5/SLC2A5/SOAT2",6,0.816496580927726]
["BP","GO:0003018","vascular process in circulatory system","11/463","173/18670",0.00400637685205603,0.0515409019797538,0.0435857420644873,"CRP/AGT/NTS/SOD2/HMOX1/AKAP12/HMGCR/HBB/CEACAM1/AGTR1/KEL",11,-2.11057941204435]
["BP","GO:0097191","extrinsic apoptotic signaling pathway","13/463","224/18670",0.00403663294758491,0.0515409019797538,0.0435857420644873,"AGT/LCN2/SERPINE1/G0S2/HSPA1A/HMOX1/HSPA1B/TNFSF10/TNFRSF1A/ATF3/BAG3/HGF/IL33",13,-1.38675049056307]
["BP","GO:0046461","neutral lipid catabolic process","5/463","43/18670",0.00406636818257462,0.0515409019797538,0.0435857420644873,"APOA4/LIPC/FGF21/PNPLA2/PLIN5",5,0.447213595499958]
["BP","GO:0046464","acylglycerol catabolic process","5/463","43/18670",0.00406636818257462,0.0515409019797538,0.0435857420644873,"APOA4/LIPC/FGF21/PNPLA2/PLIN5",5,0.447213595499958]
["BP","GO:0060612","adipose tissue development","5/463","43/18670",0.00406636818257462,0.0515409019797538,0.0435857420644873,"UBB/DGAT2/LRP5/PPARGC1A/NR1H4",5,-2.23606797749979]
["BP","GO:1901658","glycosyl compound catabolic process","5/463","43/18670",0.00406636818257462,0.0515409019797538,0.0435857420644873,"FUCA1/GUSB/NT5E/NAGA/UPP2",5,-1.34164078649987]
["BP","GO:0006706","steroid catabolic process","4/463","27/18670",0.00416741096473446,0.0526585817580953,0.0445309118356454,"SCARB1/CYP7A1/HSD17B11/HSD17B14",4,1]
["BP","GO:0032642","regulation of chemokine production","7/463","82/18670",0.0042330349620146,0.0533232157984239,0.045092961911145,"LBP/EGR1/HMOX1/EPHA2/NR1H4/ALOX15B/IL33",7,-1.88982236504614]
["BP","GO:0032922","circadian regulation of gene expression","6/463","62/18670",0.00428466407590868,0.0538080206342642,0.0455029387977515,"EGR1/PPARGC1A/NR0B2/CRY2/PER1/NR1D1",6,-1.63299316185545]
["BP","GO:0043620","regulation of DNA-templated transcription in response to stress","9/463","127/18670",0.00441583156154549,0.0552856709876674,0.0467525189310256,"CREB3L3/UBB/EGR1/HSPA1A/HMOX1/JUN/DNAJB1/ATF3/BAG3",9,-1]
["BP","GO:0042574","retinal metabolic process","3/463","14/18670",0.00449880075874578,0.0561527143484915,0.0474857371486357,"CYP1B1/RDH10/RDH11",3,0.577350269189626]
["BP","GO:0045088","regulation of innate immune response","21/463","452/18670",0.00461887743191035,0.0573020733522454,0.0484576965663577,"A2M/LBP/MUC13/MUC5B/UBB/TKFC/LAMP1/HSPA1A/HSPA1B/MUC5AC/GRAMD4/PRKACA/PIK3AP1/TSPAN6/MUCL1/S100A1/CEACAM1/PVR/NR1D1/NR1H4/DUSP10",21,-1.09108945117996]
["BP","GO:0052547","regulation of peptidase activity","21/463","452/18670",0.00461887743191035,0.0573020733522454,0.0484576965663577,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/TNFSF10/GRAMD4/CYFIP2/AIFM1/HERPUD1/RARRES1/TNFSF14/PCOLCE2/SPOCK3/WFDC2/HGF/SERPINA12",21,-1.52752523165195]
["BP","GO:0006520","cellular amino acid metabolic process","18/463","366/18670",0.0047488731417613,0.0587368176506669,0.0496709930458035,"SEPHS2/OAT/PEPD/COMT/SHMT2/PHGDH/PSAT1/P4HA1/FN3K/GCAT/KYNU/PRODH/SLC3A1/DDC/NR1H4/CTPS1/NIT2/BCKDK",18,-2.82842712474619]
["BP","GO:0008209","androgen metabolic process","4/463","28/18670",0.00476816820221748,0.0587978331924047,0.0497225910497568,"SCARB1/CYP17A1/HSD17B11/PPARGC1A",4,0]
["BP","GO:0052548","regulation of endopeptidase activity","20/463","425/18670",0.00490188479658567,0.0601574251745594,0.0508723347129627,"A2M/AHSG/AGT/ITIH2/SERPINA5/SERPINE1/SERPINA7/TFPI/SLPI/TNFSF10/GRAMD4/CYFIP2/AIFM1/HERPUD1/RARRES1/TNFSF14/SPOCK3/WFDC2/HGF/SERPINA12",20,-1.78885438199983]
["BP","GO:0050729","positive regulation of inflammatory response","10/463","153/18670",0.00490781143339102,0.0601574251745594,0.0508723347129627,"AGT/PLA2G2A/LBP/TGM2/SERPINE1/CREB3L3/TNFRSF1A/AGTR1/IL17RC/IL33",10,-2.5298221281347]
["BP","GO:0046503","glycerolipid catabolic process","6/463","64/18670",0.00501406664816865,0.0610940144571502,0.0516643646799082,"APOA4/SCARB1/LIPC/FGF21/PNPLA2/PLIN5",6,0.816496580927726]
["BP","GO:0048247","lymphocyte chemotaxis","6/463","64/18670",0.00501406664816865,0.0610940144571502,0.0516643646799082,"SAA1/CCL25/CCL20/CXCL16/TNFSF14/CXCL13",6,1.63299316185545]
["BP","GO:0033673","negative regulation of kinase activity","14/463","257/18670",0.00508403397705225,0.0617627154363559,0.0522298539763388,"AHSG/ERRFI1/CDKN1A/LRP5/TRIB1/DUSP6/HMGCR/FBXO7/CEACAM1/EPHA1/GPRC5A/SMPD1/DUSP5/DUSP10",14,-3.20713490294909]
["BP","GO:0034976","response to endoplasmic reticulum stress","15/463","285/18670",0.00521171287201142,0.063126486680517,0.0533831318469186,"CCND1/CREB3L3/ACADVL/AGR2/HSPA1A/JUN/FBXO2/FGF21/THBS4/AIFM1/HERPUD1/ATF3/STC2/PDIA5/CHAC1",15,-0.258198889747161]
["BP","GO:0071222","cellular response to lipopolysaccharide","12/463","205/18670",0.00525736025886781,0.0634915424773004,0.0536918425443758,"LBP/LCN2/SERPINE1/TFPI/SCARB1/TRIB1/PPARGC1A/MRC1/CD55/NR1D1/NR1H4/CXCL13",12,-1.73205080756888]
["BP","GO:0031116","positive regulation of microtubule polymerization","4/463","29/18670",0.00542444956210656,0.0651388664499702,0.0550849077607673,"HSPA1A/HSPA1B/MET/FES",4,1]
["BP","GO:0001933","negative regulation of protein phosphorylation","20/463","429/18670",0.00542558706874447,0.0651388664499702,0.0550849077607673,"ERRFI1/IGFBP3/JUN/CDKN1A/LRP5/TRIB1/PPARGC1A/DUSP6/HMGCR/FBXO7/ATF3/CEACAM1/PER1/EPHA1/GPRC5A/SMPD1/PID1/DUSP5/DUSP10/HGF",20,-4.02492235949962]
["BP","GO:0008625","extrinsic apoptotic signaling pathway via death domain receptors","7/463","86/18670",0.00550040167336304,0.065706155341187,0.0555646375741558,"SERPINE1/HMOX1/TNFSF10/TNFRSF1A/ATF3/BAG3/HGF",7,-1.88982236504614]
["BP","GO:0032352","positive regulation of hormone metabolic process","3/463","15/18670",0.00552098618401767,0.065706155341187,0.0555646375741558,"EGR1/PPARGC1A/RDH10",3,-0.577350269189626]
["BP","GO:0046321","positive regulation of fatty acid oxidation","3/463","15/18670",0.00552098618401767,0.065706155341187,0.0555646375741558,"CPT1A/PPARGC1A/PLIN5",3,-0.577350269189626]
["BP","GO:0030856","regulation of epithelial cell differentiation","10/463","156/18670",0.00561728436781598,0.0666584411647497,0.0563699413752762,"ERRFI1/SERPINE1/CCND1/AQP3/TNFRSF1A/CLDN5/CEACAM1/HES1/MAFF/ALOX15B",10,-1.89736659610103]
["BP","GO:0006643","membrane lipid metabolic process","12/463","207/18670",0.00567145709866349,0.0669133872101681,0.056585537380568,"CYP1B1/SERINC2/SCCPDH/FUCA1/SPTSSA/TNFRSF1A/ELOVL6/NEU4/NAGA/SMPD1/ENPP7/CPTP",12,-0.577350269189626]
["BP","GO:0006733","oxidoreduction coenzyme metabolic process","12/463","207/18670",0.00567145709866349,0.0669133872101681,0.056585537380568,"IDH2/H6PD/ENO3/PPARGC1A/ALDOC/GCK/HMGCR/KYNU/NT5E/KCNAB2/PGM2/NADK",12,-1.73205080756888]
["BP","GO:0010821","regulation of mitochondrion organization","11/463","182/18670",0.00584449148408242,0.0687115214055255,0.0581061357835017,"HSPA1A/SREBF1/TNFSF10/PPARGC1A/PPIF/BNIP3/FBXO7/ABLIM3/BAG3/PID1/HGF",11,-2.11057941204435]
["BP","GO:0006112","energy reserve metabolic process","7/463","87/18670",0.00585743062299179,0.0687115214055255,0.0581061357835017,"G6PC/PYGL/PPP1R1A/GCK/NR1D1/PGM2/PID1",7,-1.88982236504614]
["BP","GO:0097193","intrinsic apoptotic signaling pathway","15/463","289/18670",0.00590781354921838,0.0690498944764992,0.0583922821415694,"SOD2/UBB/CYP1B1/VNN1/HSPA1A/HMOX1/CDKN1A/PPIF/AIFM1/BNIP3/HERPUD1/TNFRSF1A/PRODH/EPHA2/CHAC1",15,-1.80739222823013]
["BP","GO:0070371","ERK1 and ERK2 cascade","16/463","317/18670",0.00592000805111168,0.0690498944764992,0.0583922821415694,"AGT/PLA2G2A/CHI3L1/ERRFI1/FGF19/CCL25/JUN/AKAP12/CCL20/FGF21/DUSP6/HMGCR/ATF3/CEACAM1/EPHA2/DUSP10",16,-1]
["BP","GO:0006953","acute-phase response","5/463","47/18670",0.00597782878514529,0.0695262245635932,0.0587950923275803,"CRP/SAA1/AHSG/SAA2/LBP",5,-2.23606797749979]
["BP","GO:0006469","negative regulation of protein kinase activity","13/463","235/18670",0.00600538538701274,0.0696488605507937,0.0588987998744145,"ERRFI1/CDKN1A/LRP5/TRIB1/DUSP6/HMGCR/FBXO7/CEACAM1/EPHA1/GPRC5A/SMPD1/DUSP5/DUSP10",13,-3.05085107923876]
["BP","GO:0033559","unsaturated fatty acid metabolic process","8/463","110/18670",0.0060934998672553,0.0704711538320429,0.0595941750324195,"CYP2D6/CYP2A7/CYP1B1/HPGD/TNFRSF1A/ELOVL6/ALOX15B/CYP2D7",8,-1.41421356237309]
["BP","GO:0042759","long-chain fatty acid biosynthetic process","4/463","30/18670",0.00613843140296106,0.0705919611340522,0.0596963361452955,"CYP2D6/HPGD/ELOVL6/ALOX15B",4,-1]
["BP","GO:0048265","response to pain","4/463","30/18670",0.00613843140296106,0.0705919611340522,0.0596963361452955,"RELN/COMT/VWA1/THBS4",4,1]
["BP","GO:0071216","cellular response to biotic stimulus","13/463","236/18670",0.00621683474186689,0.0712618590671835,0.0602628376499541,"LBP/LCN2/TXNIP/SERPINE1/TFPI/SCARB1/TRIB1/PPARGC1A/MRC1/CD55/NR1D1/NR1H4/CXCL13",13,-1.9414506867883]
["BP","GO:0006767","water-soluble vitamin metabolic process","7/463","88/18670",0.00623149622522024,0.0712618590671835,0.0602628376499541,"VNN1/AKR1A1/SHMT2/PSAT1/AMN/KYNU/BTD",7,-2.64575131106459]
["BP","GO:0006766","vitamin metabolic process","9/463","134/18670",0.006252764623694,0.0713059007504269,0.0603000816517507,"VNN1/RXRA/AKR1A1/SHMT2/PSAT1/RDH10/AMN/KYNU/BTD",9,-2.33333333333333]
["BP","GO:0002218","activation of innate immune response","16/463","319/18670",0.00627647981553982,0.0713775232356111,0.0603606494541242,"LBP/MUC13/MUC5B/UBB/TKFC/HSPA1A/HSPA1B/MUC5AC/GRAMD4/PRKACA/PIK3AP1/TSPAN6/MUCL1/S100A1/NR1D1/NR1H4",16,-0.5]
["BP","GO:0009612","response to mechanical stimulus","12/463","210/18670",0.00634073614909749,0.0717098723602352,0.0606417016411214,"AGT/CHI3L1/IGFBP2/TXNIP/FOS/JUN/FOSB/BNIP3/TNFRSF1A/BAG3/TNFSF14/ADGRV1",12,-1.73205080756888]
["BP","GO:0097529","myeloid leukocyte migration","12/463","210/18670",0.00634073614909749,0.0717098723602352,0.0606417016411214,"SAA1/LBP/SERPINE1/CCL25/CCL20/THBS4/CD99L2/CALCA/CD9/IL17RC/MPP1/CXCL13",12,1.15470053837925]
["BP","GO:0006111","regulation of gluconeogenesis","5/463","48/18670",0.00653995373084991,0.0733744983442822,0.0620493983632901,"DGAT2/PPARGC1A/GCK/NR1D1/SERPINA12",5,-0.447213595499958]
["BP","GO:0009069","serine family amino acid metabolic process","5/463","48/18670",0.00653995373084991,0.0733744983442822,0.0620493983632901,"SEPHS2/SHMT2/PHGDH/PSAT1/GCAT",5,-1.34164078649987]
["BP","GO:0032602","chemokine production","7/463","89/18670",0.00662308128480275,0.0733744983442822,0.0620493983632901,"LBP/EGR1/HMOX1/EPHA2/NR1H4/ALOX15B/IL33",7,-1.88982236504614]
["BP","GO:0051048","negative regulation of secretion","13/463","238/18670",0.00665751472340353,0.0733744983442822,0.0620493983632901,"SREBF1/IDH2/HMOX1/COMT/HMGCR/TNFRSF1A/CEACAM1/PIM3/TFF2/NR1H4/CPTP/ENHO/IL33",13,-3.05085107923876]
["BP","GO:0016114","terpenoid biosynthetic process","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"HMGCS1/LSS/RDH10",3,1.73205080756888]
["BP","GO:0019377","glycolipid catabolic process","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"FUCA1/NEU4/NAGA",3,-1.73205080756888]
["BP","GO:0042448","progesterone metabolic process","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"CYP17A1/EGR1/PPARGC1A",3,-0.577350269189626]
["BP","GO:0070293","renal absorption","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"SGK1/AQP3/HBB",3,-1.73205080756888]
["BP","GO:0090036","regulation of protein kinase C signaling","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"AKAP12/SEZ6/ADGRV1",3,-0.577350269189626]
["BP","GO:0090083","regulation of inclusion body assembly","3/463","16/18670",0.00667134784079077,0.0733744983442822,0.0620493983632901,"HSPA1A/HSPA1B/DNAJB1",3,1.73205080756888]
["BP","GO:0030203","glycosaminoglycan metabolic process","10/463","160/18670",0.00668507276072723,0.0733744983442822,0.0620493983632901,"ITIH2/SDC1/SDC4/FUCA1/GUSB/CHPF/PIM1/HS3ST3B1/SPOCK3/HGF",10,-2.5298221281347]
["BP","GO:0019915","lipid storage","6/463","68/18670",0.00674024586060671,0.0737822635115611,0.0623942263876596,"CRP/PLIN2/SCARB1/DGAT2/PNPLA2/PLIN5",6,-0.816496580927726]
["BP","GO:0071219","cellular response to molecule of bacterial origin","12/463","212/18670",0.0068205720915639,0.0744624590476336,0.0629694360958699,"LBP/LCN2/SERPINE1/TFPI/SCARB1/TRIB1/PPARGC1A/MRC1/CD55/NR1D1/NR1H4/CXCL13",12,-1.73205080756888]
["BP","GO:0022900","electron transport chain","11/463","186/18670",0.00684927569731785,0.0745769540021789,0.0630662591502755,"COX3/ND2/AKR1A1/PHGDH/SDHA/PPARGC1A/UQCRC2/SLC25A18/GLRX/GLRX5/NDUFA5",11,-3.3166247903554]
["BP","GO:0002082","regulation of oxidative phosphorylation","4/463","31/18670",0.00691220964858432,0.0746664546208555,0.0631419456580859,"SHMT2/AK4/PPIF/SLC25A33",4,-1]
["BP","GO:0030149","sphingolipid catabolic process","4/463","31/18670",0.00691220964858432,0.0746664546208555,0.0631419456580859,"NEU4/NAGA/SMPD1/ENPP7",4,-1]
["BP","GO:2000406","positive regulation of T cell migration","4/463","31/18670",0.00691220964858432,0.0746664546208555,0.0631419456580859,"CCL20/CD99L2/TNFSF14/CXCL13",4,2]
["BP","GO:0045089","positive regulation of innate immune response","18/463","381/18670",0.00710946710383403,0.076595153481833,0.0647729565221887,"LBP/MUC13/MUC5B/UBB/TKFC/LAMP1/HSPA1A/HSPA1B/MUC5AC/GRAMD4/PRKACA/PIK3AP1/TSPAN6/MUCL1/S100A1/PVR/NR1D1/NR1H4",18,-0.471404520791032]
["BP","GO:0031960","response to corticosteroid","10/463","162/18670",0.00727483804262695,0.0781710943478077,0.0661056563674542,"IGFBP2/SDC1/ERRFI1/CCND1/FOS/CDKN1A/BCHE/FOSB/AIFM1/CPN1",10,-3.16227766016838]
["BP","GO:0016051","carbohydrate biosynthetic process","12/463","214/18670",0.0073285967162549,0.0785426045977684,0.06641982529557,"G6PC/DGAT2/AKR1A1/SLC37A4/ENO3/PPARGC1A/ALDOC/GCK/ATF3/NR1D1/PGM2/SERPINA12",12,-2.3094010767585]
["BP","GO:0006690","icosanoid metabolic process","8/463","114/18670",0.00751828571739976,0.0803651742220225,0.0679610876034844,"CYP2D6/CYP2A7/CYP1B1/HPGD/TNFRSF1A/CYP4F22/ALOX15B/CYP2D7",8,-0.707106781186547]
["BP","GO:0051271","negative regulation of cellular component movement","18/463","384/18670",0.00767999058647275,0.0815387987824873,0.0689535672731856,"SERPINE1/IGFBP3/CYP1B1/IDH2/HMOX1/CCL25/TRIB1/PPARGC1A/CHRD/CD9/EPHA1/CYGB/SEMA3B/SPOCK3/DUSP10/ALOX15B/CXCL13/IL33",18,0]
["BP","GO:0019362","pyridine nucleotide metabolic process","11/463","189/18670",0.00768783007573036,0.0815387987824873,0.0689535672731856,"IDH2/H6PD/ENO3/PPARGC1A/ALDOC/GCK/KYNU/NT5E/KCNAB2/PGM2/NADK",11,-1.50755672288882]
["BP","GO:0046496","nicotinamide nucleotide metabolic process","11/463","189/18670",0.00768783007573036,0.0815387987824873,0.0689535672731856,"IDH2/H6PD/ENO3/PPARGC1A/ALDOC/GCK/KYNU/NT5E/KCNAB2/PGM2/NADK",11,-1.50755672288882]
["BP","GO:0042573","retinoic acid metabolic process","4/463","32/18670",0.00774779621375176,0.0815410737766059,0.0689554911298323,"CYP3A5/CYP3A7/RDH10/UGT1A9",4,-1]
["BP","GO:0046685","response to arsenic-containing substance","4/463","32/18670",0.00774779621375176,0.0815410737766059,0.0689554911298323,"HMOX1/CDKN1A/PPIF/ATF3",4,-2]
["BP","GO:0051085","chaperone cofactor-dependent protein refolding","4/463","32/18670",0.00774779621375176,0.0815410737766059,0.0689554911298323,"HSPA1A/HSPA1B/DNAJB1/HSPA6",4,2]
["BP","GO:0031113","regulation of microtubule polymerization","5/463","50/18670",0.00777339286672354,0.0816006933240159,0.0690059086063529,"HSPA1A/HSPA1B/MET/FES/MAP2",5,1.34164078649987]
["BP","GO:0006544","glycine metabolic process","3/463","17/18670",0.00795362693732034,0.0830667058198711,0.0702456471451305,"SHMT2/PHGDH/GCAT",3,-1.73205080756888]
["BP","GO:0006577","amino-acid betaine metabolic process","3/463","17/18670",0.00795362693732034,0.0830667058198711,0.0702456471451305,"CPT1A/CHDH/CROT",3,-1.73205080756888]
["BP","GO:0070372","regulation of ERK1 and ERK2 cascade","15/463","300/18670",0.00821525767965342,0.0855808268206134,0.0723717222669883,"PLA2G2A/CHI3L1/ERRFI1/FGF19/CCL25/JUN/AKAP12/CCL20/FGF21/DUSP6/HMGCR/ATF3/CEACAM1/EPHA2/DUSP10",15,-0.774596669241483]
["BP","GO:0019369","arachidonic acid metabolic process","5/463","51/18670",0.00844694452061518,0.0877710428106562,0.0742238859960014,"CYP2D6/CYP2A7/CYP1B1/ALOX15B/CYP2D7",5,-0.447213595499958]
["BP","GO:0044272","sulfur compound biosynthetic process","11/463","192/18670",0.00860424303906468,0.0889479713265231,0.0752191596670184,"FASN/ACSL4/GSTA2/GSTM1/GSTK1/ACSS2/AKR1A1/CHPF/ELOVL6/ESD/CHAC1",11,-0.904534033733291]
["BP","GO:0008286","insulin receptor signaling pathway","9/463","141/18670",0.00862808685822452,0.0889479713265231,0.0752191596670184,"AHSG/AGT/SREBF1/BAIAP2/CISH/PID1/NR1H4/ENHO/SERPINA12",9,-1.66666666666667]
["BP","GO:0097530","granulocyte migration","9/463","141/18670",0.00862808685822452,0.0889479713265231,0.0752191596670184,"SAA1/LBP/CCL25/CCL20/THBS4/CD99L2/IL17RC/MPP1/CXCL13",9,1]
["BP","GO:0031112","positive regulation of microtubule polymerization or depolymerization","4/463","33/18670",0.00864711592280318,0.0889479713265231,0.0752191596670184,"HSPA1A/HSPA1B/MET/FES",4,1]
["BP","GO:0002532","production of molecular mediator involved in inflammatory response","6/463","72/18670",0.00886102477316609,0.09091988827404,0.0768867180555158,"LBP/SERPINE1/CHID1/PER1/IL17RC/DUSP10",6,-1.63299316185545]
["BP","GO:1990266","neutrophil migration","8/463","118/18670",0.00918047750632252,0.093962187277211,0.0794594487323547,"SAA1/LBP/CCL25/CCL20/THBS4/CD99L2/MPP1/CXCL13",8,1.41421356237309]
["BP","GO:0046434","organophosphate catabolic process","13/463","248/18670",0.00924652684734048,0.0944021967905535,0.0798315442995219,"SCARB1/LIPC/ENO3/PPARGC1A/ALDOC/GCK/NT5E/SMPD1/UPP2/PGM2/ENPP7/NUDT16/SMPDL3A",13,-1.38675049056307]
["BP","GO:0034375","high-density lipoprotein particle remodeling","3/463","18/18670",0.00937103811784095,0.0952062939861767,0.080511531874768,"APOA4/SCARB1/LIPC",3,0.577350269189626]
["BP","GO:0035296","regulation of tube diameter","9/463","143/18670",0.00941830705041562,0.0952062939861767,0.080511531874768,"CRP/AGT/NTS/SOD2/HMOX1/HMGCR/HBB/AGTR1/KEL",9,-1.66666666666667]
["BP","GO:0050880","regulation of blood vessel size","9/463","143/18670",0.00941830705041562,0.0952062939861767,0.080511531874768,"CRP/AGT/NTS/SOD2/HMOX1/HMGCR/HBB/AGTR1/KEL",9,-1.66666666666667]
["BP","GO:0097746","regulation of blood vessel diameter","9/463","143/18670",0.00941830705041562,0.0952062939861767,0.080511531874768,"CRP/AGT/NTS/SOD2/HMOX1/HMGCR/HBB/AGTR1/KEL",9,-1.66666666666667]
["BP","GO:0031100","animal organ regeneration","6/463","73/18670",0.00945815596865385,0.0953736220090366,0.0806530333961693,"REG1A/CCND1/HMOX1/CDKN1A/NR0B2/HGF",6,-1.63299316185545]
["BP","GO:0050728","negative regulation of inflammatory response","10/463","169/18670",0.00966071575036068,0.0971768311596477,0.0821779234525702,"SAA1/TNFRSF1A/NT5E/CHID1/FNDC4/NR1D1/MVK/NR1H4/DUSP10/HGF",10,-2.5298221281347]
["BP","GO:0035150","regulation of tube size","9/463","144/18670",0.00983334750202029,0.0985768614207235,0.0833618638862417,"CRP/AGT/NTS/SOD2/HMOX1/HMGCR/HBB/AGTR1/KEL",9,-1.66666666666667]
["BP","GO:0071383","cellular response to steroid hormone stimulus","13/463","250/18670",0.0098480547926419,0.0985768614207235,0.0833618638862417,"ERRFI1/TFPI/RXRA/PPARGC1A/NR0B2/AIFM1/NR4A1/CRY2/PER1/CCNE1/PGRMC2/NR1D1/NR1H4",13,-2.49615088301353]
["BP","GO:0030195","negative regulation of blood coagulation","5/463","53/18670",0.00991314748972401,0.098986404446171,0.0837081953625219,"SERPINE1/TFPI/TSPAN8/CEACAM1/CD9",5,-0.447213595499958]
["BP","GO:0006022","aminoglycan metabolic process","10/463","170/18670",0.0100452168890705,0.0992339537813153,0.0839175363141815,"ITIH2/SDC1/SDC4/FUCA1/GUSB/CHPF/PIM1/HS3ST3B1/SPOCK3/HGF",10,-2.5298221281347]
["BP","GO:0005977","glycogen metabolic process","6/463","74/18670",0.0100834410966226,0.0992339537813153,0.0839175363141815,"G6PC/PYGL/PPP1R1A/GCK/NR1D1/PGM2",6,-1.63299316185545]
["BP","GO:0009064","glutamine family amino acid metabolic process","6/463","74/18670",0.0100834410966226,0.0992339537813153,0.0839175363141815,"OAT/PHGDH/PRODH/NR1H4/CTPS1/NIT2",6,-1.63299316185545]
["BP","GO:1901616","organic hydroxy compound catabolic process","6/463","74/18670",0.0100834410966226,0.0992339537813153,0.0839175363141815,"SCARB1/TKFC/CYP7A1/ALDH1B1/COMT/GK",6,-0.816496580927726]
["BP","GO:0002698","negative regulation of immune effector process","8/463","120/18670",0.0101076108272615,0.0992339537813153,0.0839175363141815,"A2M/TKFC/HMOX1/TSPAN6/CEACAM1/CD55/DUSP10/IL33",8,-2.82842712474619]
["BP","GO:0003014","renal system process","8/463","120/18670",0.0101076108272615,0.0992339537813153,0.0839175363141815,"AGT/COMT/PRKACA/SGK1/AQP3/HBB/ADCY1/AGTR1",8,-2.82842712474619]
["BP","GO:0022612","gland morphogenesis","8/463","120/18670",0.0101076108272615,0.0992339537813153,0.0839175363141815,"TGM2/LRP5/RXRA/CEACAM1/EPHA2/ESRP2/HGF/GLI2",8,-2.12132034355964]
["BP","GO:0019432","triglyceride biosynthetic process","6/463","41/18670",0.000484869574687128,0.0102852644495808,0.00869776946357221,"ACSL4/SCARB1/SREBF1/DGAT2/PLIN5/GK",6,0]
["BP","GO:0034383","low-density lipoprotein particle clearance","6/463","43/18670",0.000630523669116183,0.0126752303666031,0.0107188524093687,"SCARB1/HMOX1/DGAT2/FGF21/NR1H4/SOAT2",6,0]
["BP","GO:0046460","neutral lipid biosynthetic process","6/463","43/18670",0.000630523669116183,0.0126752303666031,0.0107188524093687,"ACSL4/SCARB1/SREBF1/DGAT2/PLIN5/GK",6,0]
["BP","GO:0046463","acylglycerol biosynthetic process","6/463","43/18670",0.000630523669116183,0.0126752303666031,0.0107188524093687,"ACSL4/SCARB1/SREBF1/DGAT2/PLIN5/GK",6,0]
["BP","GO:0044275","cellular carbohydrate catabolic process","6/463","45/18670",0.000807976814526712,0.0149676790890152,0.0126574696021832,"G6PC/TKFC/PYGL/GUSB/GK/PGM2",6,-2.44948974278318]
["BP","GO:0010043","response to zinc ion","6/463","53/18670",0.00192810150969273,0.0291278508512252,0.0246320678398888,"MT1G/MT1B/MT1M/MT1F/MT1H/MT1A",6,-1.63299316185545]
["BP","GO:0050994","regulation of lipid catabolic process","6/463","54/18670",0.00212454299107288,0.0317440839615049,0.0268444944204329,"APOA4/SCARB1/CPT1A/FGF21/PNPLA2/PLIN5",6,0.816496580927726]
["BP","GO:0010823","negative regulation of mitochondrion organization","6/463","55/18670",0.00233571504239218,0.0337653556074051,0.0285537897803603,"HSPA1A/PPARGC1A/PPIF/BNIP3/BAG3/HGF",6,-0.816496580927726]
["BP","GO:0071398","cellular response to fatty acid","6/463","57/18670",0.00280499406152979,0.0390876812492713,0.0330546328719444,"CPT1A/SREBF1/DGAT2/PPARGC1A/PID1/NR1H4",6,-2.44948974278318]
["BP","GO:0001836","release of cytochrome c from mitochondria","6/463","59/18670",0.00334149523587289,0.0444105619308393,0.0375559453347724,"SOD2/JUN/TNFSF10/PPIF/BNIP3/HGF",6,-2.44948974278318]
["CC","GO:0031526","brush border membrane","6/473","53/19717",0.00163231188140264,0.0404637210815983,0.0365565321002422,"CDHR5/CDHR2/NPC1L1/AMN/SLC3A1/SLC27A4",6,-2.44948974278318]
["CC","GO:1904724","tertiary granule lumen","6/473","55/19717",0.00198002159028703,0.0443757779940799,0.0400908396299603,"LYZ/OLFM4/ALDOC/HBB/NIT2/CRISP3",6,0]
["MF","GO:0016408","C-acyltransferase activity","6/454","20/17697",7.87449797320134e-06,0.00106305722638218,0.000921730710126304,"HADHA/HADHB/ACSM1/GCAT/SPTSSA/ACAT2",6,-0.816496580927726]
["MF","GO:0016878","acid-thiol ligase activity","6/454","30/17697",9.70340440580336e-05,0.00630839213541258,0.0054697325961628,"ACSL4/ACSS2/ACSM1/SUCLG1/ACSF2/SLC27A4",6,0]
["MF","GO:0016712","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen","6/454","32/17697",0.000141797224234329,0.00681773926887168,0.00591136535437451,"CYP3A5/CYP3A7/CYP2D6/CYP2A7/CYP1B1/CYP2D7",6,-1.63299316185545]
["MF","GO:0015020","glucuronosyltransferase activity","6/454","33/17697",0.000169588838331625,0.00688891045853614,0.00597307479913621,"UGT2B4/UGT3A1/CHPF/UGT2B17/UGT2B11/UGT1A9",6,-1.63299316185545]
["MF","GO:0016877","ligase activity, forming carbon-sulfur bonds","6/454","40/17697",0.000505077221236939,0.014822918449345,0.0128523082383404,"ACSL4/ACSS2/ACSM1/SUCLG1/ACSF2/SLC27A4",6,0]
["CC","GO:0045177","apical part of cell","19/473","384/19717",0.00247598346760599,0.0501606190180411,0.0453170946785452,"IGFBP2/MUC13/CDHR5/AKR1A1/SLC22A18/CDHR2/NPC1L1/ITPK1/AMN/SHROOM1/CEACAM1/HOMER2/CD9/PTPRH/ABCG5/UPK3A/CEACAM5/SLC2A5/SLC44A4",19,-0.229415733870562]
["CC","GO:0089717","spanning component of membrane","3/473","12/19717",0.00256806442130069,0.0501606190180411,0.0453170946785452,"CDHR5/CDHR2/NPC1L1",3,-1.73205080756888]
["CC","GO:0005903","brush border","8/473","99/19717",0.00263310336052709,0.0501606190180411,0.0453170946785452,"CDHR5/ESPN/CDHR2/NPC1L1/AMN/SLC3A1/SLC27A4/SOAT2",8,-2.12132034355964]
["CC","GO:0005775","vacuolar lumen","11/473","172/19717",0.00299281773388526,0.0526166666294261,0.0475359855997302,"LYZ/SDC1/SDC4/FUCA1/CTSF/GUSB/TOLLIP/CHID1/NEU4/ACP2/SMPD1",11,-2.11057941204435]
["CC","GO:1904813","ficolin-1-rich granule lumen","9/473","124/19717",0.00303823271875951,0.0526166666294261,0.0475359855997302,"HSPA1A/HSPA1B/PYGL/GUSB/HSPA6/ALDOC/HBB/COMMD9/PGM2",9,-0.333333333333333]
["CC","GO:0034364","high-density lipoprotein particle","4/473","26/19717",0.00321562290061957,0.0532674923972199,0.0481239674371899,"SAA1/APOA4/SAA2/LIPC",4,-1]
["CC","GO:0005777","peroxisome","9/473","134/19717",0.00507136480107258,0.0760027461594854,0.0686638983123407,"ACSL4/SYT7/IDH2/GSTK1/IDI1/FNDC5/HMGCR/MVK/CROT",9,-0.333333333333333]
["CC","GO:0042579","microbody","9/473","134/19717",0.00507136480107258,0.0760027461594854,0.0686638983123407,"ACSL4/SYT7/IDH2/GSTK1/IDI1/FNDC5/HMGCR/MVK/CROT",9,-0.333333333333333]
["CC","GO:0101002","ficolin-1-rich granule","11/473","185/19717",0.00518653910799638,0.0760027461594854,0.0686638983123407,"LAMP1/HSPA1A/HSPA1B/PYGL/GUSB/HSPA6/ALDOC/HBB/COMMD9/CD55/PGM2",11,-0.904534033733291]
["CC","GO:0031091","platelet alpha granule","7/473","91/19717",0.0062703466002533,0.0862098169369467,0.0778853712899063,"A2M/AHSG/SERPINA5/SERPINE1/SCCPDH/CD9/HGF",7,-1.13389341902768]
["CC","GO:0070820","tertiary granule","10/473","164/19717",0.00633562959116669,0.0862098169369467,0.0778853712899063,"LYZ/LAMP1/OLFM4/ALDOC/HBB/CEACAM1/KCNAB2/CD55/NIT2/CRISP3",10,-0.632455532033676]
["CC","GO:0097440","apical dendrite","3/473","17/19717",0.00726164354646387,0.0954029721104391,0.0861908326567581,"PPARGC1A/SEZ6/MAP2",3,0.577350269189626]
["MF","GO:0008028","monocarboxylic acid transmembrane transporter activity","6/454","50/17697",0.00168549112592723,0.040326411703355,0.0349652786075094,"SLC22A9/CEACAM1/SLC16A14/SLC6A11/SLC16A13/SLC16A9",6,0.816496580927726]
["MF","GO:0030170","pyridoxal phosphate binding","6/454","54/17697",0.00251388325185021,0.0499079763234968,0.0432730367810748,"OAT/PYGL/SHMT2/GCAT/KYNU/DDC",6,-2.44948974278318]
["MF","GO:0070279","vitamin B6 binding","6/454","54/17697",0.00251388325185021,0.0499079763234968,0.0432730367810748,"OAT/PYGL/SHMT2/GCAT/KYNU/DDC",6,-2.44948974278318]
["KEGG","hsa00380","Tryptophan metabolism","6/268","42/8076",0.00242478040405751,0.03244587112096,0.0261317186402187,"CYP1B1/ALDH1B1/HADHA/ACAT2/KYNU/DDC",6,-1.63299316185545]
["KEGG","hsa00860","Porphyrin and chlorophyll metabolism","6/268","42/8076",0.00242478040405751,0.03244587112096,0.0261317186402187,"UGT2B4/HMOX1/GUSB/UGT2B17/UGT2B11/UGT1A9",6,-1.63299316185545]
["BP","GO:0044342","type B pancreatic cell proliferation","5/463","22/18670",0.000170483786545242,0.00450297175558853,0.00380795364310561,"REG1A/ERRFI1/IGFBP3/NR4A1/NR1D1",5,-1.34164078649987]
["BP","GO:1901685","glutathione derivative metabolic process","5/463","22/18670",0.000170483786545242,0.00450297175558853,0.00380795364310561,"GSTA2/GSTM1/GSTK1/AKR1A1/ESD",5,-1.34164078649987]
["BP","GO:1901687","glutathione derivative biosynthetic process","5/463","22/18670",0.000170483786545242,0.00450297175558853,0.00380795364310561,"GSTA2/GSTM1/GSTK1/AKR1A1/ESD",5,-1.34164078649987]
["BP","GO:0046835","carbohydrate phosphorylation","5/463","24/18670",0.000264138999461219,0.00614423331701267,0.00519589216045424,"TKFC/FGGY/GCK/ITPK1/XYLB",5,0.447213595499958]
["BP","GO:0050996","positive regulation of lipid catabolic process","5/463","24/18670",0.000264138999461219,0.00614423331701267,0.00519589216045424,"APOA4/CPT1A/FGF21/PNPLA2/PLIN5",5,0.447213595499958]
["BP","GO:0010743","regulation of macrophage derived foam cell differentiation","5/463","30/18670",0.000783567596552244,0.0145814806376586,0.0123308795457432,"CRP/AGT/PLA2G2A/AGTR1/ALOX15B",5,-0.447213595499958]
["BP","GO:0046320","regulation of fatty acid oxidation","5/463","30/18670",0.000783567596552244,0.0145814806376586,0.0123308795457432,"ACADVL/CPT1A/DGAT2/PPARGC1A/PLIN5",5,-1.34164078649987]
["BP","GO:0045922","negative regulation of fatty acid metabolic process","5/463","32/18670",0.00106310369241235,0.0183439337132866,0.0155126110053222,"ACADVL/DGAT2/CYP7A1/CEACAM1/PLIN5",5,-0.447213595499958]
["BP","GO:0051385","response to mineralocorticoid","5/463","32/18670",0.00106310369241235,0.0183439337132866,0.0155126110053222,"CCND1/FOS/CDKN1A/FOSB/AIFM1",5,-2.23606797749979]
["BP","GO:0010737","protein kinase A signaling","5/463","33/18670",0.00122772832312888,0.0204321941255677,0.0172785556472867,"AKAP12/PRKACA/MYOM1/MROH2B/ADGRV1",5,-1.34164078649987]
["BP","GO:0006099","tricarboxylic acid cycle","5/463","34/18670",0.00141045617140117,0.0230056078315394,0.0194547718504443,"IDH2/FH/SDHA/SUCLG1/FAHD1",5,-1.34164078649987]
["BP","GO:0006101","citrate metabolic process","5/463","35/18670",0.00161245823207295,0.0252927356402554,0.0213888893941841,"IDH2/FH/SDHA/SUCLG1/FAHD1",5,-1.34164078649987]
["BP","GO:0019433","triglyceride catabolic process","5/463","35/18670",0.00161245823207295,0.0252927356402554,0.0213888893941841,"APOA4/LIPC/FGF21/PNPLA2/PLIN5",5,0.447213595499958]
["BP","GO:0006084","acetyl-CoA metabolic process","5/463","38/18670",0.00234601797205987,0.0337653556074051,0.0285537897803603,"FASN/HMGCS1/ACSS2/KYNU/MVK",5,-0.447213595499958]
["BP","GO:0072350","tricarboxylic acid metabolic process","5/463","39/18670",0.00263707283059841,0.0372281936843789,0.0314821507798119,"IDH2/FH/SDHA/SUCLG1/FAHD1",5,-1.34164078649987]
["BP","GO:0042572","retinol metabolic process","5/463","41/18670",0.00329627250341986,0.0439878047117265,0.0371984392299047,"CYP2D6/CYP1B1/DGAT2/RDH10/RDH11",5,-0.447213595499958]
["BP","GO:0050873","brown fat cell differentiation","5/463","41/18670",0.00329627250341986,0.0439878047117265,0.0371984392299047,"LAMB3/PPARGC1A/FNDC5/BNIP3/DUSP10",5,-0.447213595499958]
["CC","GO:0031528","microvillus membrane","5/473","23/19717",0.000183063183613668,0.0087588184019141,0.00791306428353616,"SCARB1/CDHR5/CDHR2/CEACAM1/PTPRH",5,-0.447213595499958]
["MF","GO:0016405","CoA-ligase activity","5/454","26/17697",0.000457855637660956,0.0140478434282339,0.01218027437988,"ACSL4/ACSS2/ACSM1/ACSF2/SLC27A4",5,0.447213595499958]
["KEGG","hsa00900","Terpenoid backbone biosynthesis","5/268","22/8076",0.000641763722944347,0.0118761819768128,0.00956500889685237,"HMGCS1/IDI1/HMGCR/ACAT2/MVK",5,-0.447213595499958]
["KEGG","hsa00052","Galactose metabolism","5/268","31/8076",0.00324470130808691,0.039641785546627,0.0319272668759124,"G6PC/GCK/GALM/GALT/PGM2",5,-1.34164078649987]
["KEGG","hsa00640","Propanoate metabolism","5/268","34/8076",0.00490086383945699,0.0474876806512901,0.0382463058251634,"HADHA/ACSS2/SUCLG1/ACAT2/ECHDC1",5,-2.23606797749979]
["BP","GO:0110096","cellular response to aldehyde","4/463","10/18670",6.9629867066727e-05,0.0024364502202665,0.00206039255764701,"AKR1A1/RDH11/AIFM1/ESD",4,-2]
["BP","GO:0070857","regulation of bile acid biosynthetic process","4/463","11/18670",0.000107276216658067,0.00332718811362217,0.00281364813866333,"FGF19/CYP7A1/NR1D1/NR1H4",4,0]
["BP","GO:0010896","regulation of triglyceride catabolic process","4/463","12/18670",0.000157766591197071,0.00436416502946493,0.00369057125495852,"APOA4/FGF21/PNPLA2/PLIN5",4,1]
["BP","GO:0097201","negative regulation of transcription from RNA polymerase II promoter in response to stress","4/463","12/18670",0.000157766591197071,0.00436416502946493,0.00369057125495852,"HSPA1A/JUN/DNAJB1/BAG3",4,1]
["BP","GO:0006012","galactose metabolic process","4/463","13/18670",0.000223430958670208,0.00540916447086968,0.00457427864774905,"PPARGC1A/GALM/GALT/PGM2",4,-2]
["BP","GO:0034374","low-density lipoprotein particle remodeling","4/463","13/18670",0.000223430958670208,0.00540916447086968,0.00457427864774905,"AGT/PLA2G2A/LIPC/AGTR1",4,-1]
["BP","GO:0061469","regulation of type B pancreatic cell proliferation","4/463","13/18670",0.000223430958670208,0.00540916447086968,0.00457427864774905,"REG1A/ERRFI1/NR4A1/NR1D1",4,-1]
["MF","GO:0003707","steroid hormone receptor activity","6/454","56/17697",0.00302762413872821,0.0567679526011539,0.0492210240097335,"RXRA/NR0B2/NR4A1/PGRMC2/NR1D1/NR1H4",6,-2.44948974278318]
["MF","GO:0016836","hydro-lyase activity","6/454","56/17697",0.00302762413872821,0.0567679526011539,0.0492210240097335,"FASN/FH/HADHA/HADHB/ENO3/ECHDC1",6,-0.816496580927726]
["MF","GO:0008514","organic anion transmembrane transporter activity","13/454","211/17697",0.00322225409640308,0.0587843652722183,0.0509693677837869,"SLC22A7/SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/SLC25A4/SLC6A11/SLC44A4/SLC16A13/SLC16A9",13,-0.277350098112615]
["MF","GO:0017017","MAP kinase tyrosine/serine/threonine phosphatase activity","3/454","13/17697",0.00395995727399642,0.0703413463144101,0.0609899236659837,"DUSP6/DUSP5/DUSP10",3,-1.73205080756888]
["MF","GO:0004033","aldo-keto reductase (NADP) activity","4/454","26/17697",0.0040832937030009,0.0706723910134771,0.0612769581341025,"AKR1A1/RDH10/RDH11/KCNAB2",4,0]
["MF","GO:0005179","hormone activity","9/454","122/17697",0.00421534863795259,0.0711340082654499,0.0616772063868852,"AGT/NTS/ANGPTL8/CCL25/SST/FNDC5/CALCA/STC2/ENHO",9,2.33333333333333]
["MF","GO:0015605","organophosphate ester transmembrane transporter activity","4/454","27/17697",0.00469774842417973,0.0773409801541785,0.0670590018958647,"SLC37A4/SLC25A4/SLC25A33/SLC44A4",4,0]
["MF","GO:0070330","aromatase activity","3/454","14/17697",0.00494483269626764,0.0791423571961287,0.068620897623466,"CYP3A5/CYP2A7/CYP2D7",3,-1.73205080756888]
["MF","GO:0030145","manganese ion binding","6/454","62/17697",0.00504166127323486,0.0791423571961287,0.068620897623466,"SOD2/PEPD/PRKACA/FAM20C/PIM1/NUDT16",6,-2.44948974278318]
["MF","GO:1901567","fatty acid derivative binding","4/454","28/17697",0.00537140570126161,0.0824022465534452,0.0714474059785037,"ACADVL/HADHA/OXER1/SOAT2",4,-1]
["MF","GO:0033293","monocarboxylic acid binding","6/454","64/17697",0.00589175979433878,0.0833981408457529,0.0723109026280524,"SERPINA5/RXRA/PYGL/UGT1A9/NR1H4/OXER1",6,-2.44948974278318]
["MF","GO:0015037","peptide disulfide oxidoreductase activity","3/454","15/17697",0.0060645485527027,0.0833981408457529,0.0723109026280524,"GLRX/GLRX5/PDIA5",3,-1.73205080756888]
["MF","GO:0033549","MAP kinase phosphatase activity","3/454","15/17697",0.0060645485527027,0.0833981408457529,0.0723109026280524,"DUSP6/DUSP5/DUSP10",3,-1.73205080756888]
["MF","GO:0070492","oligosaccharide binding","3/454","15/17697",0.0060645485527027,0.0833981408457529,0.0723109026280524,"REG1A/REG1B/CHID1",3,1.73205080756888]
["MF","GO:0005342","organic acid transmembrane transporter activity","10/454","153/17697",0.00617764006264836,0.0833981408457529,0.0723109026280524,"SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/SLC6A11/SLC16A13/SLC16A9",10,0]
["MF","GO:0046943","carboxylic acid transmembrane transporter activity","10/454","153/17697",0.00617764006264836,0.0833981408457529,0.0723109026280524,"SLC22A9/SLC25A18/CEACAM1/SLC1A7/SLC16A14/SLC3A1/SFXN5/SLC6A11/SLC16A13/SLC16A9",10,0]
["MF","GO:0005539","glycosaminoglycan binding","13/454","229/17697",0.00638008342352286,0.0844422806054496,0.0732162308251539,"SAA1/REG1A/SERPINA5/LIPC/SOD3/REG1B/THBS4/COL5A3/CHRD/GREM2/PCOLCE2/SPOCK3/CXCL13",13,1.38675049056307]
["MF","GO:0016209","antioxidant activity","7/454","86/17697",0.00657891938778128,0.0853994343606224,0.0740461372389958,"APOA4/SOD2/GSTK1/PRXL2A/SOD3/HBB/CYGB",7,0.377964473009227]
["MF","GO:0004879","nuclear receptor activity","5/454","47/17697",0.00687456098288851,0.0859320122861064,0.0745079124071348,"SREBF1/RXRA/NR4A1/NR1D1/NR1H4",5,-2.23606797749979]
["MF","GO:0098531","transcription factor activity, direct ligand regulated sequence-specific DNA binding","5/454","47/17697",0.00687456098288851,0.0859320122861064,0.0745079124071348,"SREBF1/RXRA/NR4A1/NR1D1/NR1H4",5,-2.23606797749979]
["MF","GO:0016747","transferase activity, transferring acyl groups other than amino-acyl groups","13/454","232/17697",0.00708891603743021,0.0867265453055795,0.0751968174501398,"FASN/CPT1A/DGAT2/HADHA/HADHB/ACSM1/GCAT/SPTSSA/ACAT2/ELOVL6/NAT8/CROT/SOAT2",13,-1.38675049056307]
["MF","GO:0003996","acyl-CoA ligase activity","3/454","16/17697",0.0073235749369156,0.0867265453055795,0.0751968174501398,"ACSL4/ACSM1/ACSF2",3,1.73205080756888]
["MF","GO:0030169","low-density lipoprotein particle binding","3/454","16/17697",0.0073235749369156,0.0867265453055795,0.0751968174501398,"CRP/SCARB1/LIPC",3,-0.577350269189626]
["MF","GO:0031625","ubiquitin protein ligase binding","15/454","290/17697",0.00817658424328654,0.0951585235210071,0.0825078192244522,"TXNIP/UBB/HSPA1A/HSPA1B/JUN/CDKN1A/TRIB1/SLC22A18/PPARGC1A/PRKACA/TOLLIP/FBXO7/PER1/DTX1/KCNH2",15,-1.80739222823013]
["MF","GO:0005005","transmembrane-ephrin receptor activity","3/454","17/17697",0.00872575966143754,0.0998286062961075,0.0865570449912448,"EPHB4/EPHA1/EPHA2",3,0.577350269189626]
["BP","GO:1904251","regulation of bile acid metabolic process","4/463","13/18670",0.000223430958670208,0.00540916447086968,0.00457427864774905,"FGF19/CYP7A1/NR1D1/NR1H4",4,0]
["BP","GO:0010867","positive regulation of triglyceride biosynthetic process","4/463","14/18670",0.000306694516962483,0.00697559640246893,0.00589893722976379,"SCARB1/SREBF1/DGAT2/PLIN5",4,0]
["BP","GO:0030299","intestinal cholesterol absorption","4/463","15/18670",0.000410059057658254,0.00892969033006858,0.00755142351980962,"APOA4/NPC1L1/ABCG5/SOAT2",4,0]
["BP","GO:0009070","serine family amino acid biosynthetic process","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"SEPHS2/SHMT2/PHGDH/PSAT1",4,-1]
["BP","GO:0010744","positive regulation of macrophage derived foam cell differentiation","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"AGT/PLA2G2A/AGTR1/ALOX15B",4,0]
["BP","GO:0034433","steroid esterification","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"APOA4/AGT/AGTR1/SOAT2",4,0]
["BP","GO:0034434","sterol esterification","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"APOA4/AGT/AGTR1/SOAT2",4,0]
["BP","GO:0034435","cholesterol esterification","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"APOA4/AGT/AGTR1/SOAT2",4,0]
["BP","GO:0098856","intestinal lipid absorption","4/463","17/18670",0.000687378723652769,0.0132741910124266,0.0112253655516085,"APOA4/NPC1L1/ABCG5/SOAT2",4,0]
["BP","GO:0044241","lipid digestion","4/463","19/18670",0.00107631019717909,0.0183600581135466,0.0155262466601843,"APOA4/NPC1L1/ABCG5/SOAT2",4,0]
["BP","GO:0052695","cellular glucuronidation","4/463","19/18670",0.00107631019717909,0.0183600581135466,0.0155262466601843,"UGT2B4/UGT2B17/UGT2B11/UGT1A9",4,-1]
["BP","GO:0016137","glycoside metabolic process","4/463","20/18670",0.0013192459714894,0.0218663684505165,0.0184913701266935,"FUCA1/AKR1A1/GUSB/NAGA",4,-2]
["BP","GO:0010893","positive regulation of steroid biosynthetic process","4/463","21/18670",0.00159801869948049,0.0252598013732552,0.0213610384173595,"SREBF1/CYP7A1/PPARGC1A/NR1D1",4,-1]
["BP","GO:0051412","response to corticosterone","4/463","21/18670",0.00159801869948049,0.0252598013732552,0.0213610384173595,"CCND1/FOS/CDKN1A/FOSB",4,-2]
["BP","GO:0010866","regulation of triglyceride biosynthetic process","4/463","22/18670",0.00191524868013276,0.0290408448017168,0.0245584908731254,"SCARB1/SREBF1/DGAT2/PLIN5",4,0]
["BP","GO:0044321","response to leptin","4/463","22/18670",0.00191524868013276,0.0290408448017168,0.0245584908731254,"CCND1/GCK/NR1D1/PID1",4,-1]
["BP","GO:0006541","glutamine metabolic process","4/463","23/18670",0.00227352645395317,0.0332422046517295,0.028111385364857,"PHGDH/NR1H4/CTPS1/NIT2",4,-2]
["BP","GO:0051004","regulation of lipoprotein lipase activity","4/463","23/18670",0.00227352645395317,0.0332422046517295,0.028111385364857,"APOA4/ANGPTL8/ANGPTL4/LIPC",4,0]
["BP","GO:0070841","inclusion body assembly","4/463","23/18670",0.00227352645395317,0.0332422046517295,0.028111385364857,"HSPA1A/HSPA1B/DNAJB1/BAG3",4,2]
["BP","GO:0051156","glucose 6-phosphate metabolic process","4/463","25/18670",0.00312338641076345,0.0427663677781457,0.0361655268614715,"G6PC/H6PD/GCK/PGM2",4,0]
["KEGG","hsa00100","Steroid biosynthesis","4/268","20/8076",0.00377436620440398,0.0417632388908603,0.0336358732404382,"DHCR7/LSS/FDFT1/SOAT2",4,2]
["BP","GO:0046322","negative regulation of fatty acid oxidation","3/463","10/18670",0.00159676222222847,0.0252598013732552,0.0213610384173595,"ACADVL/DGAT2/PLIN5",3,-0.577350269189626]
["BP","GO:0090084","negative regulation of inclusion body assembly","3/463","11/18670",0.00215531947431738,0.0320868288285648,0.0271343378029851,"HSPA1A/HSPA1B/DNAJB1",3,1.73205080756888]
["BP","GO:0006563","L-serine metabolic process","3/463","12/18670",0.00282117043535747,0.0390876812492713,0.0330546328719444,"SHMT2/PHGDH/PSAT1",3,-1.73205080756888]
["BP","GO:0032252","secretory granule localization","3/463","12/18670",0.00282117043535747,0.0390876812492713,0.0330546328719444,"KIF1C/SYBU/MAP2",3,0.577350269189626]
["BP","GO:0006703","estrogen biosynthetic process","3/463","13/18670",0.00360049227836366,0.0469439980497478,0.0396983543531279,"HSD17B2/HSD17B11/HSD17B14",3,-0.577350269189626]
["BP","GO:0010872","regulation of cholesterol esterification","3/463","13/18670",0.00360049227836366,0.0469439980497478,0.0396983543531279,"APOA4/AGT/AGTR1",3,-0.577350269189626]
["BP","GO:0032536","regulation of cell projection size","3/463","13/18670",0.00360049227836366,0.0469439980497478,0.0396983543531279,"CDHR5/CDHR2/KEL",3,-0.577350269189626]
["MF","GO:0004303","estradiol 17-beta-dehydrogenase activity","3/454","11/17697",0.00237350440434008,0.0499079763234968,0.0432730367810748,"HSD17B2/HSD17B11/HSD17B14",3,-0.577350269189626]
["MF","GO:0016832","aldehyde-lyase activity","3/454","11/17697",0.00237350440434008,0.0499079763234968,0.0432730367810748,"CYP17A1/SHMT2/ALDOC",3,-0.577350269189626]
["KEGG","hsa04913","Ovarian steroidogenesis","6/268","51/8076",0.00649474084015151,0.0588716830994378,0.0474149161505118,"SCARB1/CYP17A1/CYP1B1/HSD17B2/PRKACA/ADCY1",6,0]
["KEGG","hsa04928","Parathyroid hormone synthesis, secretion and action","9/268","106/8076",0.0084559326192047,0.0742536583123913,0.0598034708266122,"CREB3L3/FOS/EGR1/CDKN1A/LRP5/RXRA/PRKACA/ADCY1/ARAF",9,-3]
["KEGG","hsa04010","MAPK signaling pathway","18/268","294/8076",0.00888796758221129,0.075682390624284,0.0609541636419594,"FGF19/FOS/HSPA1A/HSPA1B/JUN/MET/HSPA6/FGF21/PRKACA/DUSP6/TNFRSF1A/NR4A1/MAP2K3/EPHA2/ARAF/DUSP5/DUSP10/HGF",18,-1.4142135623731]
["KEGG","hsa04931","Insulin resistance","9/268","108/8076",0.00951328374235967,0.0769995801070799,0.0620150205020498,"AGT/G6PC/CREB3L3/CPT1A/SREBF1/PYGL/PPARGC1A/TNFRSF1A/SLC27A4",9,-3]
["KEGG","hsa05218","Melanoma","7/268","72/8076",0.00959298486941313,0.0769995801070799,0.0620150205020498,"CCND1/FGF19/CDKN1A/MET/FGF21/ARAF/HGF",7,-0.377964473009227]
["KEGG","hsa00260","Glycine, serine and threonine metabolism","5/268","40/8076",0.00986471488916327,0.0769995801070799,0.0620150205020498,"SHMT2/PHGDH/PSAT1/GCAT/CHDH",5,-2.23606797749979]
["KEGG","hsa05219","Bladder cancer","5/268","41/8076",0.0109380508125577,0.083070061576452,0.0669041514850616,"CCND1/CDKN1A/MMP1/UPK3A/ARAF",5,-0.447213595499958]
["KEGG","hsa00650","Butanoate metabolism","4/268","28/8076",0.012960775271933,0.0958415224056101,0.0771902128383823,"HMGCS1/HADHA/ACSM1/ACAT2",4,0]
["KEGG","hsa04151","PI3K-Akt signaling pathway","20/268","354/8076",0.0138134326737425,0.0995275533672218,0.0801589210487084,"G6PC/CCND1/FGF19/CREB3L3/RELN/CDKN1A/RXRA/MET/FGF21/LAMB3/THBS4/SGK1/PIK3AP1/NR4A1/CCNE1/GNB5/EPHA2/GNG4/HGF/SGK2",20,0]
["Enrichment analysis of genes in royalblue and salmon module"]
["ONTOLOGY","ID","Description","GeneRatio","BgRatio","pvalue","p.adjust","qvalue","geneID","Count","zscore"]
["BP","GO:0022900","electron transport chain","9/108","186/18670",1.33440877085241e-06,0.00258608419791198,0.00245109821593417,"ASPH/GPX2/NQO1/COX6C/NDUFB9/UQCRB/CYC1/GLDC/BID",9,2.33333333333333]
["BP","GO:0030647","aminoglycoside antibiotic metabolic process","3/108","10/18670",2.19325233288244e-05,0.0212526151056309,0.0201432911625256,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["BP","GO:0006378","mRNA polyadenylation","4/108","44/18670",0.000120288248644557,0.056300534634821,0.0533618124695903,"VIRMA/PABPC1/HSF1/CPSF1",4,2]
["BP","GO:0043631","RNA polyadenylation","4/108","46/18670",0.000143318820204086,0.056300534634821,0.0533618124695903,"VIRMA/PABPC1/HSF1/CPSF1",4,2]
["BP","GO:1902644","tertiary alcohol metabolic process","3/108","19/18670",0.000170510406103182,0.056300534634821,0.0533618124695903,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["BP","GO:0016137","glycoside metabolic process","3/108","20/18670",0.000199757487153396,0.056300534634821,0.0533618124695903,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["BP","GO:0042775","mitochondrial ATP synthesis coupled electron transport","5/108","97/18670",0.000249254325275001,0.056300534634821,0.0533618124695903,"COX6C/NDUFB9/UQCRB/CYC1/BID",5,2.23606797749979]
["BP","GO:0015980","energy derivation by oxidation of organic compounds","8/108","285/18670",0.000251643364282748,0.056300534634821,0.0533618124695903,"RB1CC1/MTFR1/COX6C/NDUFB9/UQCRB/CYC1/MYC/BID",8,2.12132034355964]
["BP","GO:0042773","ATP synthesis coupled electron transport","5/108","98/18670",0.000261457591183379,0.056300534634821,0.0533618124695903,"COX6C/NDUFB9/UQCRB/CYC1/BID",5,2.23606797749979]
["CC","GO:0005852","eukaryotic translation initiation factor 3 complex","3/112","16/19717",9.46756061654319e-05,0.0227221454797036,0.0199317065611436,"EIF3E/EIF3H/COPS5",3,1.73205080756888]
["CC","GO:0016605","PML body","5/112","99/19717",0.000252898914222778,0.0303478697067334,0.0266209383392398,"TP53INP1/EIF3E/HSF1/RGS14/TRIM16",5,2.23606797749979]
["CC","GO:0035578","azurophil granule lumen","4/112","91/19717",0.00180368907634623,0.0698077832972982,0.0612348976292089,"SDCBP/FTL/GGH/NAPRT",4,2]
["CC","GO:0005766","primary lysosome","5/112","155/19717",0.00192178137819289,0.0698077832972982,0.0612348976292089,"SDCBP/CPNE3/FTL/GGH/NAPRT",5,2.23606797749979]
["CC","GO:0042582","azurophil granule","5/112","155/19717",0.00192178137819289,0.0698077832972982,0.0612348976292089,"SDCBP/CPNE3/FTL/GGH/NAPRT",5,2.23606797749979]
["CC","GO:0005750","mitochondrial respiratory chain complex III","2/112","14/19717",0.00278321939094298,0.0698077832972982,0.0612348976292089,"UQCRB/CYC1",2,1.41421356237309]
["CC","GO:0045275","respiratory chain complex III","2/112","14/19717",0.00278321939094298,0.0698077832972982,0.0612348976292089,"UQCRB/CYC1",2,1.41421356237309]
["CC","GO:0005775","vacuolar lumen","5/112","172/19717",0.00301687512384428,0.0698077832972982,0.0612348976292089,"SDC2/SDCBP/FTL/GGH/NAPRT",5,2.23606797749979]
["CC","GO:0042470","melanosome","4/112","106/19717",0.00314169183366854,0.0698077832972982,0.0612348976292089,"YWHAZ/SDCBP/GGH/RAB2A",4,2]
["CC","GO:0048770","pigment granule","4/112","106/19717",0.00314169183366854,0.0698077832972982,0.0612348976292089,"YWHAZ/SDCBP/GGH/RAB2A",4,2]
["CC","GO:0033290","eukaryotic 48S preinitiation complex","2/112","15/19717",0.00319952340112617,0.0698077832972982,0.0612348976292089,"EIF3E/EIF3H",2,1.41421356237309]
["CC","GO:1990204","oxidoreductase complex","4/112","112/19717",0.0038273194393593,0.0759424818329107,0.0666162121341322,"NDUFB9/UQCRB/CYC1/GLDC",4,1]
["CC","GO:0016282","eukaryotic 43S preinitiation complex","2/112","17/19717",0.00411355109928266,0.0759424818329107,0.0666162121341322,"EIF3E/EIF3H",2,1.41421356237309]
["CC","GO:0070993","translation preinitiation complex","2/112","18/19717",0.0046106427640142,0.0790395902402434,0.0693329738949503,"EIF3E/EIF3H",2,1.41421356237309]
["MF","GO:0009055","electron transfer activity","7/107","114/17697",5.86396528919541e-06,0.00185887699667494,0.00172832661155233,"ASPH/GPX2/NQO1/COX6C/UQCRB/CYC1/GLDC",7,1.88982236504614]
["MF","GO:0004032","alditol:NADP+ 1-oxidoreductase activity","3/107","13/17697",5.88104025983284e-05,0.00932144881183505,0.00866679617238524,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["MF","GO:0008106","alcohol dehydrogenase (NADP+) activity","3/107","21/17697",0.000264023381848482,0.0278984706819896,0.0259391392693246,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["MF","GO:0016655","oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor","4/107","60/17697",0.000474790518956429,0.0320116807691086,0.0297634753954853,"AKR1C1/AKR1C2/NQO1/NDUFB9",4,2]
["MF","GO:0004033","aldo-keto reductase (NADP) activity","3/107","26/17697",0.000504916100459126,0.0320116807691086,0.0297634753954853,"AKR1B10/AKR1C1/AKR1C2",3,1.73205080756888]
["MF","GO:0016709","oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen","3/107","39/17697",0.00167643255665753,0.0795432860417769,0.0739568988600283,"SQLE/AKR1C1/AKR1C2",3,1.73205080756888]
["MF","GO:0008135","translation factor activity, RNA binding","4/107","85/17697",0.00175647634792567,0.0795432860417769,0.0739568988600283,"EIF3E/EIF3H/EEF1D/COPS5",4,2]
["MF","GO:0003730","mRNA 3'-UTR binding","4/107","91/17697",0.00225530660279952,0.0893665241359311,0.083090243261035,"YBX3/PABPC1/CPSF1/EXOSC4",4,2]