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{"sheet":"Figure 1","index":0,"n_rows":58,"n_cols":16,"rows_kept":58,"merged":[[1,3,1,15],[2,4,2,6],[2,7,2,9],[2,10,2,12],[2,13,2,15],[11,3,11,15],[12,4,12,6],[12,7,12,9],[12,10,12,12],[12,13,12,15],[21,3,21,15],[22,4,22,6],[22,7,22,9],[22,10,22,12],[22,13,22,15],[31,3,31,15],[32,4,32,6],[32,7,32,9],[32,10,32,12],[32,13,32,15],[42,4,42,6],[42,7,42,9],[48,4,48,6],[48,7,48,9],[54,4,54,6],[54,7,54,9]],"flags":["formulas_cached_only"]}
[]
[{"$nulls":3},"24h"]
[null,null,"Figure. 1A","Cetuximab (μg/ml)","HCT116",null,null,"HCT116-R",null,null,"SW480",null,null,"HT-29"]
[{"$nulls":3},0,0,0,0,0,0,0,0,0,0,0,0,0]
[{"$nulls":3},0.01,0.5,0.4,0.5,0.5,0.4,0.5,0.6,0.5,0.5,0.9,0.8,0.8]
[{"$nulls":3},0.5,0.7,1,0.8,0.7,0.7,0.8,1.3,1.1,1.3,1.6,1.7,1.6]
[{"$nulls":3},1,2.7,3.5,2,1.1,1.3,1.3,2.3,0.25,2.3,3.6,3.5,3.3]
[{"$nulls":3},5,4.7,4.4,4.9,1.8,1.8,1.9,3.6,3.8,3.6,5.5,5.3,5.7]
[{"$nulls":3},10,6.6,6.8,6.5,3.3,3.5,3.6,5.5,5.2,5.7,7.3,7.2,7.8]
[{"$nulls":3},20,8,7.9,8.5,5.2,4.4,4.3,7.3,7.6,7.8,8.5,8.7,9]
[]
[{"$nulls":3},"48h"]
[{"$nulls":3},"Cetuximab (μg/ml)","HCT116",null,null,"HCT116-R",null,null,"SW480",null,null,"HT-29"]
[{"$nulls":3},0,0,0,0,0,0,0,0,0,0,0,0,0]
[{"$nulls":3},0.01,0.8,0.6,0.8,0.8,0.6,0.8,1.3,1.1,1.3,3.6,3.5,3.3]
[{"$nulls":3},0.5,1.1,1.4,1.3,1.1,1.4,1.3,2.8,2.5,2.3,5.5,5.3,5.7]
[{"$nulls":3},1,2.1,2.7,2.6,2.1,1.5,2.3,3.6,3.8,3.6,7.3,7.2,7.8]
[{"$nulls":3},5,4.5,4.8,4.7,3.2,2.6,2.8,7.3,7.6,7.8,9.3,9.9,9]
[{"$nulls":3},10,11.6,13.9,13.2,5.6,6.1,5.9,12,10.9,11.1,14,13.6,13.7]
[{"$nulls":3},20,20.7,21.6,22,6.3,7.8,8.2,16.9,16,16,18.8,19.8,20]
[]
[{"$nulls":3},"24h"]
[null,null,"Figure. 1B","PA-MSHA (×109/ml)","HCT116",null,null,"HCT116-R",null,null,"SW480",null,null,"HT-29"]
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[{"$nulls":3},0.01,1,0.8,1.2,0.7,0.8,0.8,0.7,0.8,0.9,0.7,0.8,0.9]
[{"$nulls":3},0.1,5.6,5.9,6,4.9,5.9,6.5,2.2,2.5,2.2,2.2,1.8,2]
[{"$nulls":3},0.2,11.8,12,12.2,10.8,11,11.6,5.6,5.9,6,5.6,5,4.6]
[{"$nulls":3},0.3,33.3,35,37.6,35,35.5,36.8,21.8,22,23.3,15.8,16,17.3]
[{"$nulls":3},0.4,41,41.8,42.1,40,40.8,40.6,31,31,31.6,21,22,21.6]
[{"$nulls":3},0.6,43.2,43.6,44,41.6,43.5,41.9,33,35,33.8,23.1,23.9,25]
[]
[{"$nulls":3},"48h"]
[{"$nulls":3},"PA-MSHA (×109/ml)","HCT116",null,null,"HCT116-R",null,null,"SW480",null,null,"HT-29"]
[{"$nulls":3},0,0,0,0,0,0,0,0,0,0,0,0,0]
[{"$nulls":3},0.01,1.3,1.6,1.5,1.3,1.3,1.5,0.7,0.8,0.9,0.7,0.8,0.9]
[{"$nulls":3},0.1,11.1,13,12.8,10.6,12.6,12,8.8,9,9.3,2.2,1.8,2]
[{"$nulls":3},0.2,23.6,25.2,26.1,22.6,23.9,25,15.8,13,14.4,8.8,9.3,9.3]
[{"$nulls":3},0.3,72.2,73,73.9,69.9,71.6,70.2,62.2,63.6,63.9,44.3,45.3,43.3]
[{"$nulls":3},0.4,77.7,77.6,76.8,73.5,75.5,75.9,66.2,67.1,65.8,46.3,48.3,49.2]
[{"$nulls":3},0.6,79.2,79.9,80.2,78.6,77.9,79.2,68.7,69.2,67.8,50.5,51.6,51.9]
[]
[]
[null,null,"Figure. 1C","PA-MSHA (×109/ml)","HCT116-R",null,null,"SW480"]
[{"$nulls":3},0,5.2,5.8,5,4.4,4,5]
[{"$nulls":3},0.3,32.8,33,32.6,24.8,25,24.7]
[{"$nulls":3},0.4,37.8,36.8,38.5,30,30.6,30.2]
[]
[]
[null,null,"Figure. 1D","PA-MSHA (×109/ml)","HCT116-R",null,null,"SW480"]
[{"$nulls":3},0,1722,1819,1777,1148,1017,987]
[{"$nulls":3},0.3,399,476,458,418,436,490]
[{"$nulls":3},0.4,278,292,328,268,336,252]
[]
[]
[null,null,"Figure. 1E","PA-MSHA (×109/ml)","HCT116-R",null,null,"SW480"]
[{"$nulls":3},0,147,142,140,138,122,126]
[{"$nulls":3},0.3,17,15,14,43,45,41]
[{"$nulls":3},0.4,10,9,11,21,25,23]

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[]
[]
[null,null,"Figure. 2B ","PA-MSHA (×109/ml)","HCT116-R",null,null,"SW480"]
[{"$nulls":3},0,1,1,1,1,1,1]
[{"$nulls":3},0.3,23.6,25.2,23.8,20.2,21.1,20.8]
[{"$nulls":3},0.4,25.5,26.2,25.7,21.1,21.6,21.5]
[]
[null,null,"Figure. 2C","PA-MSHA (×109/ml)","HCT116-R",null,null,"SW480"]
[{"$nulls":3},0,1,1,1,1,1,1]
[{"$nulls":3},0.3,0.074,0.069,0.072,0.094,0.092,0.102]
[{"$nulls":3},0.4,0.11,0.184,0.166,0.184,0.225,0.209]
[]
[null,null,"Figure. 2D",null,"HCT116-R"]
[{"$nulls":3},"NC",1,1,1]
[{"$nulls":3},"Mimic",21.7,20.6,23.5]
[]
[]
[null,null,"Figure. 2E","NC",3.5,3.8,4]
[{"$nulls":3},"NC+PA-MSHA (0.3)",32.9,34.4,33.3]
[{"$nulls":3},"Mimic+PA-MSHA (0.3)",44.9,46,46.2]
[]
[]
[null,null,"Figure. 2F","Migration"]
[{"$nulls":3},"NC",1676,1557,1585]
[{"$nulls":3},"NC+PA-MSHA (0.3)",733,802,745]
[{"$nulls":3},"Mimic+PA-MSHA (0.3)",341,352,388]
[]
[{"$nulls":3},"Invasion"]
[{"$nulls":3},"NC",76,72,78]
[{"$nulls":3},"NC+PA-MSHA (0.3)",33,35,36]
[{"$nulls":3},"Mimic+PA-MSHA (0.3)",11,12,17]

{"sheet":"Figure 3","index":2,"n_rows":20,"n_cols":8,"rows_kept":20,"flags":["formulas_cached_only"]}
[]
[]
[]
[{"$nulls":3},"Figure 3C","NC",1,1,1]
[{"$nulls":4},"Inhibitor",0.16,0.18,0.2]
[]
[]
[{"$nulls":3},"Figure. 3E","siRNA(-) Inhibitor(-)",36.2,40.9,32.2]
[{"$nulls":4},"siRNA(+) Inhibitor(+)",37.7,41.3,34.9]
[{"$nulls":4},"siRNA(-) Inhibitor(+)",26.1,25.4,23.6]
[]
[{"$nulls":4},"Migation"]
[{"$nulls":3},"Figure. 3F","siRNA(-) Inhibitor(-)",1268,1218,1333]
[{"$nulls":4},"siRNA(+) Inhibitor(+)",1205,1393,1255]
[{"$nulls":4},"siRNA(-) Inhibitor(+)",1801,1918,1879]
[]
[{"$nulls":4},"Invasion"]
[{"$nulls":4},"siRNA(-) Inhibitor(-)",52,46,50]
[{"$nulls":4},"siRNA(+) Inhibitor(+)",53,46,46]
[{"$nulls":4},"siRNA(-) Inhibitor(+)",82,88,78]

{"sheet":"Figure 5","index":3,"n_rows":23,"n_cols":8,"rows_kept":23,"merged":[[3,3,5,3],[6,3,8,3],[9,3,11,3]],"flags":["formulas_cached_only"]}
[]
[]
[null,null,"Figure 5C and 5D","PA-MSHA (×109/ml)","larger diameter","smaller diameter","tumor volume","tumor weight"]
[{"$nulls":3},"Negative control",16.07,10.83,942.4163115000001,0.948]
[{"$nulls":4},19.67,17.29,2940.1152235,1.851]
[{"$nulls":4},16.33,12.27,1229.2644285,1.229]
[{"$nulls":3},"HCT116-R+PA-MSHA",9.23,8.43,327.96451349999995,0.253]
[{"$nulls":4},9.87,8.35,344.08053749999993,0.278]
[{"$nulls":4},9.21,7.85,283.7716125,0.178]
[{"$nulls":3},"HCT116-R OE+PA-MSHA",7.92,6.08,146.386944,0.078]
[{"$nulls":4},6.26,6.07,115.32453699999999,0.056]
[{"$nulls":4},3.5,2.3,9.257499999999999,0.007]
[]
[]
[null,null,"Figure 5E","Negative control","HCT116-R+PA-MSHA","HCT116-R OE+PA-MSHA"]
[{"$nulls":3},53,80,74]
[{"$nulls":3},55,72,84]
[{"$nulls":3},57,76,81]
[{"$nulls":3},57,75,85]
[{"$nulls":3},58,77,76]
[{"$nulls":3},62,68,86]
[{"$nulls":3},63,72,79]
[{"$nulls":3},65,74,87]

{"sheet":"Figure 6","index":4,"n_rows":54,"n_cols":9,"rows_kept":54,"flags":["formulas_cached_only"]}
[]
[]
[null,"Figure 6A","chemosensitive","chemoresistant",null,"Figure 6B","at diagnosis","remission","progression"]
[null,null,6.979397,1.510237,null,null,10.05,12.58088,8.6]
[null,null,4.605002,6.647501,null,null,4.59,4.958149,4.5]
[null,null,1.993093,0.5642571,null,null,2.01,3.170176,1.67]
[null,null,3.281528,0.5660636,null,null,20.67,52.41433,9.2]
[null,null,33,0.9475125,null,null,2.7,3.878414,0.11]
[null,null,1.174343,0.5679209,null,null,2.7,2.226986,0.08]
[null,null,12.08088,1.150671,null,null,3.6,1.777392,1.9]
[null,null,4.458149,1.207652,null,null,3.05,3.781528,0.55]
[null,null,2.670176,0.6560413,null,null,6.3,9.897734,1.3]
[null,null,1.327598,0.6637992,null,null,8.8,3.92839,4.6]
[null,null,3.378414,0.5915053,null,null,6.55,9.068461,1.32]
[null,null,1.726986,1.528114,null,null,5.65,1.246558,3.78]
[null,null,1.277392,0.8056601,null,null,3.1,1.882703,0.01]
[null,null,3.281528,1.370551,null,null,2.35,1.823591,1.11]
[null,null,9.397734,9.62611,null,null,2.25,1.586417,1.79]
[null,null,3.42839,0.6582196,null,null,3.7,2.494849,3.2]
[null,null,8.568461,2.472466,null,null,3.56,4.363585,2.3]
[null,null,1.246558,2.047565,null,null,27.96,38.53072,13.27]
[null,null,1.882703,4.612455,null,null,4.11,4.555371,0.05]
[null,null,1.823591,1.810393,null,null,11.25,15.22148,1.88]
[null,null,1.586417,3.840352,null,null,22.22,22.85664,21.11]
[null,null,2.494849,0.6358418,null,null,21.27,25.08395,1.56]
[null,null,4.363585,1.847234]
[null,null,38.53072,10.05833]
[null,null,4.555371,10.28112]
[null,null,1.381565,0.540386]
[null,null,22.85664,5.926417]
[null,null,25.08395,2.302501]
[null,null,15.22148,1.312252]
[null,null,51.91433,0.6224275]
[null,null,4.24901,2.091073]
[null,null,1.926588,1.078344]
[null,null,4.294364,0.5068961]
[null,null,1.363493,29.34002]
[null,null,4.09513,10.07983]
[null,null,2.006956,1.765757]
[null,null,1.456916,2.015717]
[null,null,1.174343,15.223]
[null,null,4.386981,1.062529]
[null,null,1.034197,0.9506252]
[null,null,1.230047,0.8789291]
[null,null,2.433955,0.8186402]
[null,null,2.180993,1.062529]
[null,null,1.289172,0.6743429]
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