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["Trial Forge: summary of all trials"]
["Note:","1. There are 120 Phase III trials, 21 Core outcome set trials and 20 Public health trials."]
[null,"2. Trials  in red are trials where it was not possible to get one or more of Time to collect for primary and secondary outcomes, data on times measured or numbers randomised."]
[null,"3. We obtained full Time to collect data for 100 Phase III trials, 17 Core outcome trials and 17 Public health trials."]
[]
["Phase 3 trials"]
["Trial ID","Title of trial","Clinical discipline","Country","Year","Pubmed ID (if available)","Number of participants randomised","Notes"]
[41,"Foldable vs rigid lenses after phacoemulsification for cataract surgery: a randomised controlled trial","Other","Nepal","2014","24556879","1200"]
[42,"Motivational counseling to reduce sitting time: a community-based randomized controlled trial in adults","Lifestyle and addiction","Denmark","2014","25113139","166"]
[43,"Assessment of the adjuvant effect of tacrolimus in the management of pemphigus vulgaris: A randomized controlled trial","Infection and immunity","Iran","2014","24552352","46"]
[44,"Impact of age of first exposure to Plasmodium falciparum on antibody responses to malaria in children: a randomized, controlled trial in Mozambique","Infection and immunity","Mozambique","2014","24674654","349"]
[45,"A Cluster Randomized-Controlled Trial of a Classroom-Based Drama Workshop Program to Improve Mental Health Outcomes among Immigrant and Refugee Youth in Special Classes","Mental health","Canada","2014","25127251","555"]
[46,"Effects of bayberry juice on inflammatory and apoptotic markers in young adults with features of non-alcoholic fatty liver disease","Gastrointestinal","China","2014","24377455","44","No secondary Time to collect data"]
[47,"Robotic Resistance/Assistance Training Improves Locomotor Function in Individuals Poststroke: A Randomized Controlled Study","Cardiovascular","USA","2014","24440365","30"]
[48,"Resistance to Erythropoiesis Stimulating Agents in Patients Treated with Online Hemodiafiltration and Ultrapure Low-Flux Hemodialysis: Results from a Randomized Controlled Trial (CONTRAST)","Gastrointestinal","The Netherlands","2014","24743493","714"]
[49,"A Text Message Alcohol Intervention for Young Adult Emergency Department Patients: A Randomized Clinical Trial","Lifestyle and addiction","USA","2014","25017822","765","Obtained timing data but secondary Time to collect = 0 so did not contribute to ratio calculations"]
[50,"Multidisciplinary Group Clinic Appointments: The Self-Management and Care of Heart Failure (SMAC-HF) Trial","Cardiovascular","USA","2014","25236883","198"]
[51,"Platelet-rich plasma injections for the treatment of hamstring injuries: a randomized controlled trial","Musculoskeletal","Malaysia","2014","25073598","28"]
[52,"Influence of counseling sessions on the prevalence of breastfeeding in the first year of life: a randomized clinical trial with adolescent mothers and grandmothers","Women and children","Brazil","2014","24654636","323"]
[53,"Diet and physical exercise in psoriasis: a randomized controlled trial","Dermatology","Italy","2014","24641585","303"]
[54,"Online CBT for preschool anxiety disorders: a randomised control trial","Mental health","Australia","2014","24927471","52"]
[55,"Family-based psychosocial support and education as part of pulmonary rehabilitation in COPD: a randomized controlled trial","Respiratory","Portugal","2014","25340477","56"]
[56,"Increasing varenicline dose in smokers who do not respond to the standard dosage: a randomized clinical trial","Lifestyle and addiction","UK","2014","25545858","200"]
[57,"Modafinil increases the latency of response in the Hayling Sentence Completion Test in healthy volunteers: a randomised controlled trial","Neurology","UK","2014","25391155","64"]
[58,"A randomized phase III study comparing pegylated liposomal doxorubicin with capecitabine as first-line chemotherapy in elderly patients with metastatic breast cancer: results of the OMEGA study of the Dutch Breast Cancer Research Group BOOG","Cancer","The Netherlands","2014","24504445","78"]
[59,"Transforaminal versus intra-articular facet corticosteroid injections for the treatment of cervical radiculopathy: a randomized, double-blind, controlled study","Neurology","Canada","2014","24874533","56"]
[60,"Simvastatin as a novel therapeutic agent for venous ulcers: a randomized, double-blind, placebo-controlled trial","Gastrointestinal","Philippines","2014","24506834","66"]
[61,"Prevention of conversion to abnormal TCD with hydroxyurea in sickle cell anemia: a phase III international randomized clinical trial","Other","USA","2015","26414435","22"]
[62,"Effect of supplemental oxygen 80% on post-tonsillectomy nausea and vomiting: a randomized controlled trial","Other","Iran","2015","26677853","102","No primary or secondary Time to collect data"]
[63,"Interactive cognitive-motor step training improves cognitive risk factors of falling in older adults – a randomized controlled trial","Other","Australia","2015","26673919","90"]
[64,"Tilt table therapies for patients with severe disorders of consciousness: a randomized, controlled trial","Neurology","Germany","2015","26623651","50"]
[65,"Evaluation of sit-stand workstations in an office setting: a randomised controlled trial","Lifestyle and addiction","UK","2015","26584856","47"]
[66,"Continuous positive airway pressure with helmet versus mask in infants with bronchiolitis: An RCT","Respiratory","Italy","2015","25780074","30"]
[67,"Ultra-low-dose buprenorphine as a time-limited treatment for severe suicidal ideation: A randomized controlled trial","Mental health","Israel","2015","26684923","88"]
[68,"Radiofrequency versus ethanol ablation for treating predominantly cystic thyroid nodules: A randomized clinical trial","Endocrinology","Korea","2015","26576124","50"]
[69,"Folic acid causes higher prevalence of detectable unmetabolized folic acid in serum than B-complex: A randomized clinical trial","Nutrition","Germany","2015","25943647","58"]
[70,"Early intervention and child physical health: Evidence from a Dublin-based randomized controlled trial","Lifestyle and addiction","Ireland","2015","26439756","233"]
[71,"Early sustained unresponsiveness after short-course egg oral immunotherapy: a randomized controlled study in egg-allergic children","Infection and immunity","Spain","2015","26236997","61"]
[72,"Diagnostic performance of the Bernese versus Ottawa ankle rules: Results of a randomised controlled trial","Musculoskeletal","The Netherlands","2015","25933807","203"]
[73,"Circuit class therapy or seven-day week therapy for increasing rehabilitation intensity of therapy after stroke (CIRCIT): a randomized controlled trial","Cardiovascular","Australia","2015","25790018","283"]
[74,"Implementation of a surgical safety checklist and postoperative outcomes: a prospective randomized controlled study","Other","India","2015","25691114","700"]
[75,"Oxybutynin as a treatment for generalized hyperhidrosis: a randomized, placebo-controlled trial","Dermatology","France","2015","26114588","62"]
[76,"Benefits of partnered strength training for prostate cancer survivors and spouses: results from a randomized controlled trial of the Exercising Together project","Cancer","USA","2015","26715587","64"]
[77,"Calcium and vitamin D supplementation do not influence menopause-related symptoms: Results of the Women’s Health Initiative Trial","Women and children","USA","2015","26044075","23020"]
[78,"Resveratrol improves treatment outcome and laboratory parameters in patients with Takayasu arteritis: A randomized double-blind and\nplacebo-controlled trial","Cardiovascular","China","2016","27771172","242"]
[79,"Tai Chi Exercise for Cancer-Related Fatigue in Patients With Lung Cancer Undergoing Chemotherapy: A Randomized Controlled Trial","Cancer","China","2016","26721747","96","Obtained timing data but secondary Time to collect = 0 so did not contribute to ratio calculations"]
[80,"Comparison of active vs. expectant management of the third stage of labor in women with low risk of postpartum hemorrhage: a randomized controlled trial","Women and children","Turkey","2016","27304659","669"]
[81,"Efficacy of Cognitive-Behavioral Therapy for Insomnia Combined With Antidepressant Pharmacotherapy in Patients With Comorbid Depression and Insomnia: A Randomized Controlled Trial","Neurology","USA","2016","27788313","150"]
[82,"Perinatal and Hemodynamic Evaluation of Sildenafil Citrate for Preeclampsia Treatment","Women and children","Brazil","2016","27400005","100","No primary or secondary Time to collect data"]
[83,"Effect of Continuous Positive Airway Pressure on Cardiovascular Biomarkers: The Sleep Apnea Stress Randomized Controlled Trial","Neurology","USA","2016","26997243","153"]
[84,"Is dextrose prolotherapy superior to placebo for the treatment of temporomandibular joint hypermobility? A randomized clinical trial","Musculoskeletal","Turkey","2016","26846795","30"]
[85,"Should Asymptomatic Bacteriuria Be Systematically Treated in Kidney Transplant Recipients? Results From a Randomized Controlled Trial","Other","Spain","2016","27088545","112"]
[86,"Is there an effect of intranasal insulin on development and behaviour in Phelan-McDermid syndrome? A randomized, double-blind, placebo-controlled trial","Other","The Netherlands","2016","27577546","25"]
[87,"Effects of Housing First on Employment and Income of Homeless Individuals: Results of a Randomized Trial","Lifestyle and addiction","Canada","2016","26876657","2148"]
[88,"Refeeding low weight hospitalized adolescents with anorexia nervosa: a multicenter randomized controlled trial","Mental health","UK","2016","26869609","36"]
[89,"Sustained-release dexamfetamine in the treatment of chronic cocaine-dependent patients on heroin-assisted treatment: a randomised, double-blind, placebo-controlled trial","Lifestyle and addiction","The Netherlands","2016","27015909","73"]
[90,"Immediate versus delayed invasive intervention for non-STEMI patients: The RIDDLE-NSTEMI Study","Cardiovascular","Serbia","2016","26777321","323"]
[91,"Effects of interventions on use of hearing protectors among farm operators: A randomized controlled trial","Other","USA","2016","26766172","491","No primary or secondary Time to collect data"]
[92,"Belotecan/cisplatin versus etoposide/cisplatin in previously untreated patients with extensive-stage small cell lung carcinoma: a multi-center randomized phase III trial","Cancer","Korea","2016","27566413","157"]
[93,"Duration of antibiotic treatment in community-acquired pneumonia: A multicenter randomized clinical trial","Respiratory","Spain","2016","12226033","312"]
[94,"Seven-day intensive preoperative rehabilitation for elderly patients with lung cancer: a randomized controlled trial","Cancer","China","2016","28032568","60"]
[95,"Effect of soy in men with type 2 diabetes mellitus and subclinical hypogonadism: A randomized controlled study","Endocrinology","UK","2016","27797674","200"]
[96,"Supported telemonitoring and glycemic control in people with type 2 diabetes: The telescot diabetes pragmatic multicenter randomized controlled trial","Endocrinology","UK","2016","27458809","321"]
[97,"A process evaluation of the supermarket healthy eating for life (SHELf) randomized controlled trial","Nutrition","Australia","2016","26912177","642","No secondary Time to collect data"]
[98,"Behavioral weight loss intervention for migraine: A randomized controlled trial","Neurology","USA","2017","29178659","110"]
[99,"Clinic and home-based behavioral intervention for obesity in pre-schoolers: A randomized trial","Lifestyle and addiction","USA","2017","29150147","167"]
[100,"Effects of clay art therapy on adults outpatients with major depressive disorder: A randomized controlled trial","Mental health","Hong Kong","2017","28433887","106"]
[101,"Effectiveness of irrigation with chlorhexidine after removal of mandibular third molars: A randomised controlled trial","Other","Australia","2017","29223633","100"]
[102,"The effects of multi-disciplinary psycho-social care on socio-economic problems in cancer patients: A cluster-randomized trial","Cancer","Germany","2017","29270828","1012"]
[103,"Clinical effects of a pharmacist intervention in acute wards: A randomized controlled trial","Other","Denmark","2017","28457021","498"]
[104,"Effects of methylprednisolone on the duration of rocuronium-induced neuromuscular block","Other","China","2017","28953616","116","No primary or secondary Time to collect data"]
[105,"Reducing trunk compensation in stroke survivors: A randomized crossover trial comparing visual and force feedback modalities","Cardiovascular","Canada","2017","28526482","15"]
[106,"Effect of Erythropoietin in patients with acute myocardial infarction: five-year results of the REVIVAL-3 trial","Cardiovascular","Germany","2017","28109258","138"]
[107,"Does azithromycin given to women in labour decrease ocular bacterial infection in neonates? A double-blind, randomized trial","Women and children","Gambia","2017","29282015","829"]
[108,"Comparison of 3D laparoscopic gastrectomy with a 2D procedure for gastric cancer: A phase 3 randomized controlled trial","Cancer","China","2017","29195739","438"]
[109,"Sutureless vs sutured gastroschisis closure: A prospective randomized controlled trial","Women and children","USA","2017","28279777","39","No primary Time to collect data"]
[110,"Application of zone model predictive control artificial pancreas during extended use of infusion set and sensor: A randomized crossover-controlled home-use trial","Endocrinology","USA","2017","28584075","19","No primary Time to collect data"]
[111,"Effect of myofascial techniques for treatment of persistent arm pain after breast cancer treatment: Randomized controlled trial","Cancer","Belgium","2017","28914087","50"]
[112,"Multidomain lifestyle intervention benefits a large elderly population at risk for cognitive decline and dementia regardless of baseline characteristics: The FINGER trial","Neurology","Finland","2017","29055814","1260"]
[113,"Mercaptopurine versus placebo to prevent recurrence of Crohn’s disease after surgical resection (TOPPIC): A multicentre, double-blind randomised controlled trial","Gastrointestinal","UK","2017","28404197","240"]
[114,"Work-focused cognitive behavioural intervention for psychological complaints in patients on sick leave due to work-related stress: Results from a randomized controlled trial","Mental health","Denmark","2017","28830555","163"]
[115,"Efficacy of guided self-help behavioural activation and physical acivity for depression: A randomized controlled trial","Mental health","Canada","2017","28644740","59"]
[116,"Effect of educational package on lifestyle of primiparous mothers during postpartum period: A randomized controlled clinical trial","Women and children","Iran","2017","28931169","220","No secondary Time to collect data"]
[117,"Acupressure, sleep, and quality of life in institutionalized older adults: A randomized controlled clinical trial","Neurology","Taiwan","2017","28152177","62"]
[118,"The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial","Endocrinology","Denmark","2018","30591062","16","No secondary Time to collect data"]
[119,"Repetitive TMS to augment cognitive processing therapy in combat veterans of recent conflicts with PTSD: A randomized clinical trial","Mental health","USA","2018","29351885","103"]
[120,"Minimally invasive versus abdominal radical hysterectomy for cervical cancer","Cancer","USA","2018","30380365","631"]
[121,"Classroom-based physical activity improves children’s math achievement – A randomized controlled trial","Women and children","Denmark","2018","30557397","505"]
[122,"Effect of a low-intensity PSA-based screening based intervention on prostate cancer mortality: The CAP randomized clinical trial","Cancer","UK","2018","29509864","415357","Obtained timing data but primary Time to collect = 0 so did not contribute to ratio calculations"]
[123,"Prophylaxis of postoperative nausea and vomiting after cardiac surgery in high-risk patients: A randomized controlled study","Other","France","2018","29336385","502"]
[124,"Effects of long-term norfloxacin therapy in patients with advanced cirrhosis","Gastrointestinal","France","2018","30144431","291"]
[125,"Cervical ripening balloon with and without oxytocin in multiparas: A randomized controlled trial","Women and children","USA","2018","29763609","195"]
[126,"Self-tracking of physical activity in people with type 2 diabetes","Endocrinology","The Netherlands","2018","29742550","72"]
[127,"An 18-mo randomized, double-blind, placebo-controlled trial of DHA-rich fish oil to prevent age-related cognitive decline in cognitively normal older adults","Neurology","Australia","2018","29722833","403"]
[128,"Effects of a combined physical and psychosocial training for children with cancer: A randomized controlled trial","Cancer","The Netherlands","2018","30587148","59"]
[129,"Comparing effects of 4 months of two self-administered exercise training programs on physical performance in patients with chronic kidney disease: RENEXC – A randomized controlled trial","Gastrointestinal","Sweden","2018","30571753","151","No secondary Time to collect data"]
[130,"Thrombus aspiration in late presenters with ST-elevation myocardial infarction: A single-center randomized trial","Cardiovascular","Egypt","2018","29869443","60","No secondary Time to collect data"]
[131,"Low-level laser therapy (830nm) on orthodontic pain: blinded randomized clinical trial","Other","Brazil","2018","29998356","62","No secondary Time to collect data"]
[132,"Managing risk of non-communicable diseases in women with bulimia nervosa or binge eating disorders: A randomized trial with 12 months follow-up","Mental health","Norway","2018","30513892","164"]
[133,"Communication-based interventions for increasing influenza vaccination rates among Aboriginal children: A randomised controlled trial","Infection and immunity","Australia","2018","30279091","5534"]
[134,"Garlic extract favourably modifies markers of endothelial function in obese patients – randomized double blind placebo-controlled nutritional intervention","Lifestyle and addiction","Poland","2018","29604599","92"]
[135,"Bag-Mask Ventilation during Tracheal Intubation\nof Critically Ill Adults","Respiratory","United States","2019","30779528","401"]
[136,"Design of the SHAPE-2 study: the effect of physical activity, in addition to weight loss, on biomarkers of postmenopausal breast cancer risk","Nutrition","The Netherlands","2019","23972905","243"]
[137,"Satisfactory analgesia with minimal emesis in day surgeries: a randomised controlled trial of morphine versus hydromorphone","Neurology","Canada","2019","31027915","402"]
[138,"Effects of home reading training on reading and quality of life in AMD-a randomized and controlled study","Other","Germany","2019","31111250","37"]
[139,"Nocturnal temperature-controlled laminar airflow device for adults with severe allergic asthma: the LASER RCT","Respiratory","UK","2019","31232684","240","No primary Time to collect data"]
[140,"A randomized trial of trigger point dry needling versus sham needling for chronic tension-type headache","Other","Turkey","2019","30813155","161"]
[141,"Cost-effectiveness and quality of life of a diet intervention postpartum: 2-year results from a randomized controlled trial","Nutrition","Sweden","2019","30621673","110"]
[142,"Discontinuing cotrimoxazole preventive therapy in HIV-infected adults who are stable on antiretroviral treatment in Uganda (COSTOP): A randomised placebo-controlled trial","Infection and immunity","Uganda","2019","30596666","2180"]
[143,"Goal-oriented cognitive rehabilitation for early-stage Alzheimer's and related dementias: the GREAT RCT","Neurology","UK","2019","30879470","475"]
[144,"Lung protective ventilation during pulmonary resection in children: a prospective, single-centre, randomised controlled trial","Respiratory","South Korea","2019","30916035","114"]
[145,"Cuff-assisted versus cap-assisted colonoscopy for adenoma detection: results of a randomized study","Gastrointestinal","Spain","2019","31096275","711"]
[146,"Selective laser trabeculoplasty versus drops for newly diagnosed ocular hypertension and glaucoma: the LiGHT RCT","Other","UK","2019","31264958","718"]
[147,"Inflammatory markers response to citrulline supplementation in patients with non-alcoholic fatty liver disease: a randomized, double blind, placebo-controlled, clinical trial","Gastrointestinal","Iran","2019","30767788","50"]
[148,"Effect of manual physiotherapy in homogeneous individuals with subacromial shoulder impingement: A randomized controlled trial","Musculoskeletal","Australia","2019","30680850","69"]
[149,"Adjuvant Chemotherapy plus Radiation for Locally Advanced Endometrial Cancer","Cancer","USA","2019","31189035","736"]
[150,"Procalcitonin-Guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients (PRODA): a Multi-Center Randomized Controlled Trial","Infection and immunity","South Korea","2019","30977312","52"]
[151,"Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception","Women and children","UK","2019","30907987","952"]
[152,"Pre-pregnancy and early pregnancy calcium supplementation among women at high risk of pre-eclampsia: a multicentre, double-blind, randomised, placebo-controlled trial","Women and children","Zimbabwe, South Africa, Argentina","2019","30696573","1355"]
[153,"White Sweet Potato as Meal Replacement for Overweight White-Collar Workers: A Randomized Controlled Trial","Nutrition","Taiwan","2019","30646532","60"]
[154,"Group singing improves depression and life quality in patients with stable COPD: a randomized community-based trial in China","Mental health","China","2019","30612266","60"]
[155,"Intralesional mycobacterium w vaccine versus cryotherapy in treatment of refractory extragenital warts: a randomized, open-label, comparative study","Dermatology","India","2015","26553733","66","No primary or secondary Time to collect data"]
[156,"The effect of omega-3 fatty acids in patients with active rheumatoid arthritis receiving DMARDs therapy: Double-blind randomized controlled trial","Rheumatoid arthritis","Iran","2015","26925896","60","No primary or secondary Time to collect data"]
[157,"The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial","Nutrition","Denmark","2015","26659070","125","No primary or secondary Time to collect data"]
[158,"Effect of fentanyl nasal packing treatment on patients with acute postoperative pain after nasal operation: A randomized double-blind controlled trial","Neurology","South Korea","2018","29519133","152","No primary or secondary Time to collect data"]
[159,"Effectiveness of aspiration or deroofing for blister management in patients with burns","Dermatology","South Korea","2018","29703044","47","No primary or secondary Time to collect data"]
[160,"The effects of neck mobilization in patients with chronic neck pain: A randomized controlled trial","Neurology","Pakistan","2018","29332752","68","No primary or secondary Time to collect data"]
[]
[]
["Core outcome set trials"]
["Trial ID","Title of trial","Clinical discipline","Country","Year","Pubmed ID (if available)","Number of participants randomised","Notes"]
[4,"Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis","Rheumatoid arthritis","Denmark","2006","16645967","160","No secondary Time to collect data"]
[5,"Direct comparison of treatment responses, remission rates, and drug adherence in patients with rheumatoid arthritis treated with adalimumab, etanercept, or infliximab: results from 8 years of surveillance of clinical practice in the DANBIO registry.","Rheumatoid arthritis","Denmark","2010","20039405","112","Obtained timing data but primary Time to collect = 0 so did not contribute to ratio calculations"]
[6,"Effects of Atorvastatin on Disease Activity and HDL Cholesterol Function in Patients With Rheumatoid Arthritis","Rheumatoid arthritis","USA","2007","17552046","20"]
[7,"A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study","Rheumatoid arthritis","Belgium","2007","18050189","44"]
[8,"Treatment of Rheumatoid Arthritis With Roxithromycin: a randomized trial","Rheumatoid arthritis","Turkey","2011","21904105","100","No primary or secondary Time to collect data"]
[9,"Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone","Rheumatoid arthritis","USA",null,null,"91"]
[10,"Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in Japan (JESMR)","Rheumatoid arthritis","Japan","2010","20574649","151","No primary or secondary Time to collect data"]
[11,"Comparison of MTX+ anti-TNF to MTX+ conventional DMARDs in patients with early rheumatoid arthritis who failed MTX alone","Rheumatoid arthritis","Sweden","2011","21149498","487"]
[12,"Switching Anti-TNF-Alpha Agents in Rheumatoid Arthritis (RA)","Rheumatoid arthritis","USA",null,null,"13"]
[30,"TNF-blocking Therapy in Combination With Disease-modifying Antirheumatic Drugs in Early Rheumatoid Arthritis (NEO-RACo)","Rheumatoid arthritis","Finland","2014","25274892","99"]
[31,"Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After Discontinuation (SURPRISE)","Rheumatoid arthritis","Japan","2016","5099201","233"]
[32,"Spacing of TNF-blocker Injections in Rheumatoid Arthritis Study (STRASS)","Rheumatoid arthritis","France","2015","26103979","137"]
[33,"Optimal management of rheumatoid arthritis patients requiring biologic therapy (ORBIT)","Rheumatoid arthritis","UK","2016","27197690","295"]
[34,"Effectiveness in daily practice of different treatment strategies for early rheumatoid arthritis","Rheumatoid arthritis","Belgium","2017","27432356","379"]
[35,"Improvement in insulin resistance is greater when infliximab is added to methotrexate during intensive treatment of early rheumatoid arthritis-results from the IDEA study.","Rheumatoid arthritis","UK","2016","27638812","79"]
[36,"Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid Arthritis (DMIRA)","Rheumatoid arthritis","India","2014","24976447","100"]
[37,"Study of Different Doses of Folic Acid in Combination With Methotrexate in Rheumatoid Arthritis (FOLVARI)","Rheumatoid arthritis","India","2015","26063325","100"]
[38,"Leflunomide Versus Sulfasalazine/Methotrexate in Rheumatoid Arthritis:an Ultrasound/Magnetic Resonance Imaging Study","Rheumatoid Arthritis","Singapore",null,null,"1"]
[39,"RA Denosumab on bone microstructure study","Rheumatoid Arthritis","Hong Kong",null,null,"40"]
[40,"Comparison of Three Different Treatment Regimes in Early Rheumatoid Arthritis: A Randomized Open-labelled Trial","Rheumatoid Arthritis","India",null,null,"60","No primary or secondary Time to collect data"]
[161,"Combination Treatment With Methotrexate, Cyclosporine, and Intraarticular Betamethasone Compared With Methotrexate and Intraarticular Betamethasone in Early Active Rheumatoid Arthritis Early Active Rheumatoid Arthritis","Rheumatoid Arthritis","Denmark","2006","16645967","160"]
[]
[]
["Public health trials"]
["Trial ID","Title of trial","Clinical discipline","Country","Year","Pubmed ID (if available)","Number of participants randomised","Notes"]
[1,"PRENACEL - a mHealth messaging system to complement antenatal care: a cluster randomized trial","Women and children","Brazil","2017","29116028","1210"]
[2,"Effects of web-based stress and depression literacy intervention on improving symptoms and knowledge of depression among workers: A randomized controlled trial","Mental health","Japan","2016","27280960","1236"]
[3,"Theory-based modifications of an advanced notification letter improves screening for bowel cancer in men: A randomised controlled trial","Cancer","Australia","2016","27485727","9216"]
[13,"A randomized, controlled trial to increase discussion of breast cancer in primary care","Cancer","USA","2014","24762560","1635"]
[14,"Effectiveness of an action-oriented educational intervention in ensuring long term improvement of knowledge, attitudes and practices of community health workers in maternal and infant health: a randomized controlled study","Women and children","Brazil","2018","30261868","59","No secondary Time to collect data"]
[15,"Metabolic syndrome from adolescence to early adulthood: effect of infancy-onset dietary counseling of low saturated fat: the Special Turku Coronary Risk Factor Intervention Project (STRIP)","Nutrition","Finland","2015","25605660","1062"]
[16,"Effectiveness of a group diabetes education programme in under-served communities in South Africa: a pragmatic cluster randomized controlled trial","Endocrinology","South Africa","2014","24766179","1570"]
[17,"Improving feeding and growth of HIV-positive children through nutrition training of frontline health workers in Tanga, Tanzania","Nutrition ","Tanzania","2017","28376725","776"]
[18,"Family-centered brief intervention for reducing obesity and cardiovascular disease risk: A randomized controlled trial","Nutrition ","New Zealand","2016","27616217","320"]
[19,"Effectiveness of a walking programme to support adults with intellectual disabilities to increase physical activity: walk well cluster-randomised controlled trial.","Lifestyle and addiction","UK","2015","26416606","102"]
[20,"Intervention of childhood and adolescents obesity in Shantou city","Nutrition","China","2015","25596004","41"]
[21,"A block randomized controlled trial of a brief smoking cessation counselling and advice through short message service on participants who joined the Quit to Win Contest in Hong Kong","Lifestyle and addiction","Hong Kong","2015","26116584","1003"]
[22,"Brief report: A randomized controlled trial examining peer support and behavioral weight loss treatment","Nutrition","USA","2015","26265590","41"]
[23,"A computerized kiosk to teach injury prevention: is it as effective as human interaction?","Lifestyle and addiction","USA","2014","25153050","357","No primary or secondary Time to collect data"]
[24,"Self-Expansion is Associated with Better Adherence and Obesity Treatment Outcomes in Adults","Nutrition","USA","2017","27436226","268"]
[25,"The Effectiveness of a Web-Based Computer-Tailored Intervention on Workplace Sitting: A Randomized Controlled Trial","Lifestyle and addiction","Belgium","2016","27245789","213"]
[26,"Effects of Awareness Material on Suicide-Related Knowledge and the Intention to Provide Adequate Help to Suicidal Individuals","Mental health","Germany","2018","28793816","273"]
[27,"A Computerized Lifestyle Application to Promote Multiple Health Behaviors at the Workplace: Testing Its Behavioral and Psychological Effects","Lifestyle and addiction","Germany","2015","26429115","560"]
[28,"The effect of test kit provision, and individual and family education on the uptake rates of fecal occult blood test in an Asian population: a randomized controlled trial","Cancer","Singapore","2014","25088807","343","No secondary Time to collect data"]
[29,"Motivational interviewing and self-determination theory in a web-based computer tailored physical activity intervention: A randomized controlled trial","Lifestyle and addiction","The Netherlands","2016","26849996","4302"]