{"text_format":"3","workbook":"xlsx","n_sheets":13,"sheets":["Table S1","Table S2","Table S3","Table S4A","Table S4B","Table S5A","Table S5B","Table S6","Table S7","Table S8A","Table S8B","Table S9","Table S10"],"read":"whole","date_system":"1900"}

{"sheet":"Table S1","index":0,"n_rows":22,"n_cols":8,"rows_kept":22,"merged":[[0,1,0,7],[1,1,1,7],[2,1,3,1],[2,2,2,4],[2,5,2,7],[10,1,10,7]]}
[null,"Table S1. Demographic information and clinical characteristics of human subjects used in this study"]
[null,"A total of 288 and 416 human post-mortem brain tissues were used for proteome and transcriptome profiling, respectively. These postmortem human brain samples were obtained from the Stanley Medical Research Institute (SMRI) and Banner Sun Health Research Institute (BSHRI). "]
[null,"Characteristics","Proteome (n = 288)",null,null,"Transcriptome (n = 416)"]
[null,null,"SCZ               (n = 49)","BP                (n = 29)","CTRL            (n = 210)","SCZ            (n = 95)","BP                 (n = 74)","CTRL                      ( n = 247)"]
[null,"Age of death (yr)"]
[null,"Mean±SD","44.94±12.15","44.14±11.89","79.00±14.43","42.57±10.31","43.93±11.46","72.55±18.83"]
[null,"Range","18-79","19-63","20-92","18-61","19-64","20-92"]
[null,"Gender"]
[null,"Male",32,14,133,67,39,156]
[null,"Female",17,15,77,28,35,91]
[null,"PMI (Hours)"]
[null,"Mean ± SD","46.81±32.76","38.97±21.97","6.46±10.93","40.09±26.52","37.54±18.92","14.01±10.52"]
[null,"Range","9-142","11-115","1-90","9-142","11-115","1-90"]
[null,"Brain bank"]
[null,"BSHRI",0,0,183,0,0,173]
[null,"SMRI",49,29,27,95,74,74]
[null,"Ethnicity"]
[null,"Asian American",1,0,0,1,0,0]
[null,"Asian",0,1,2,0,1,2]
[null,"Caucasian",48,28,206,93,72,242]
[null,"Hispanic American   ",0,0,1,0,0,2]
[null,"unknown",0,0,1,1,1,1]

{"sheet":"Table S2","index":1,"n_rows":11690,"n_cols":271,"rows_kept":281,"cut":true,"merged":[[0,1,0,13],[1,1,1,13]],"bounds":{"rows_first":125,"rows_last":31,"rows_between":125,"halvings":4}}
[null,"Table S2. Proteome profiling of human brain cortex tissues by TMT-LC/LC-MS/MS"]
[null,"A total of 288 samples were used for proteome profiling, 268 of which have been corrected for sample. We performed 29 batches of LC/LC-MS/MS runs and identified ~11,000 protein groups across all samples at the protein level FDR of 1%. We include one internal standard in each TMT 11-plex assay to normalize MS data from different batches. "]
[null,"Protein accession","Gene symbol","2014-2194","2014-2195","2014-2196","2014-2197","2014-2198","2014-2199","2014-2200","2014-2201","2014-2621","2014-2622","2014-2624","2014-2625","2014-2626","2015-1","2015-1332","2015-1333","2015-1334","2015-1335","2015-1336","2015-1337","2015-1338","2015-1339","2015-1340","2015-1341","2015-1342","2015-1343","2015-1397","2015-1398","2015-1399","2015-1400","2015-1401","2015-1402","2015-1403","2015-1404","2015-1405","2015-1406","2015-1407","2015-1425","2015-1426","2015-1427","2015-1428","2015-1429","2015-1431","2015-1432","2015-1433","2015-1434","2015-1435","2015-1436","2015-1443","2015-1444","2015-1445","2015-1446","2015-1447","2015-1448","2015-1449","2015-1450","2015-1451","2015-1452","2015-1453","2015-1467","2015-1468","2015-1469","2015-1470","2015-1471","2015-1472","2015-1473","2015-1474","2015-1475","2015-1476","2015-1478","2015-1502","2015-1503","2015-1504","2015-1505","2015-1506","2015-1507","2015-1508","2015-1509","2015-1510","2015-1511","2015-1512","2015-1513","2015-1534","2015-1535","2015-1536","2015-1537","2015-1538","2015-1539","2015-1540","2015-1541","2015-1543","2015-1552","2015-1553","2015-1554","2015-1555","2015-1556","2015-1557","2015-1558","2015-17","2015-18","2015-19","2015-20","2015-21","2015-22","2015-23","2015-24","2015-243","2015-244","2015-245","2015-246","2015-247","2015-248","2015-249","2015-250","2015-251","2015-280","2015-282","2015-283","2015-284","2015-285","2015-286","2015-287","2015-3","2015-350","2015-351","2015-352","2015-353","2015-354","2015-355","2015-37","2015-38","2015-41","2015-42","2015-43","2015-45","2015-46","2015-477","2015-478","2015-479","2015-480","2015-481","2015-482","2015-483","2015-509","2015-510","2015-511","2015-513","2015-514","2015-516","2015-517","2015-518","2015-519","2015-520","2015-6","2015-7","2015-733","2015-734","2015-735","2015-736","2015-737","2015-738","2015-739","2015-740","2015-766","2015-767","2015-768","2015-769","2015-770","2015-771","2015-772","2015-773","2015-774","2015-775","2015-776","2015-777","2015-8","2015-802","2015-803","2015-804","2015-805","2015-806","2015-807","2015-808","2015-809","2015-810","2015-811","2015-812","2015-813","2015-854","2015-855","2015-856","2015-857","2015-858","2015-859","2015-860","2015-864","2015-865","2015-891","2015-893","2015-894","2015-895","2015-896","2015-898","2015-899","2015-900","2015-901","2015-902","2015-917","2015-918","2015-919","2015-920","2015-921","2015-922","2015-923","2015-924","2015-925","2015-926","2015-927","2016-889","2016-890","2016-891","2016-892","2016-893","2016-894","2016-895","2016-896","2016-922","2016-923","2016-924","2016-925","2016-926","2016-927","2016-928","2016-929","2016-930","2016-931","2016-932","2016-933","2016-934","2016-935","2016-936","2016-937","2016-938","2016-939","2016-940","2016-942","2016-943","2016-944","2016-945","2016-946","2016-947","2016-948","2016-949","2016-950","2016-951","2016-952","2016-953","2016-954","2016-955","2016-956","2016-957","2016-958","2016-959","2016-961","2016-962","2016-963","2016-964","2016-965"]
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[{"$nulls":270},19.97]
[{"$nulls":270},15.77]
[{"$nulls":270},20.51]
[{"$nulls":270},20.58]
[{"$nulls":270},18.69]
[{"$nulls":270},15.93]
[{"$nulls":270},19.84]
[{"$nulls":270},20.75]
[{"$nulls":270},16.65]
[{"$nulls":270},23.97]
[{"$nulls":270},17.69]
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{"sheet":"Table S3","index":2,"n_rows":17163,"n_cols":419,"rows_kept":139,"cut":true,"merged":[[0,1,0,13],[1,1,1,13]],"bounds":{"rows_first":62,"rows_last":15,"rows_between":62,"halvings":5}}
[null,"Table S3. Transcriptome profiling of human brain cortex tissues by RNA-seq"]
[null,"A total of 416 samples were used for transcriptome profiling. Total RNA was isolated from  frontal cortical samples. The mRNA expression levels were nominalized and  corrected by the PEER R package. "]
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{"sheet":"Table S4A","index":3,"n_rows":886,"n_cols":12,"rows_kept":886,"merged":[[0,1,0,11],[1,1,1,11]]}
[null,"Table S4A. Significant cis-pQTLs detected in this study"]
[null,"To identify the genetic loci modulating protein expression, we performed genome-wide linkage analysis of 11,687 proteins in 268 individuals using the QTLtools (version 1.2), identifying 883 cis-acting (pQTLs) associated with protein expression at the false discovery rate (FDR) of 5%. "]
[null,"Index","Gene symbol","Protein accession","Protein Chr.","Protein start","Protein end","pQTL pos.","Nominal p","Beta p","q value","Slope"]
[null,1,"PANK4","Q9NVE7",1,{"v":2440289,"d":"2,440,289"},{"v":2458026,"d":"2,458,026"},{"v":2415447,"d":"2,415,447"},{"v":4.13073e-09,"d":"4.13E-09"},{"v":2.72618E-5,"d":"2.73E-05"},{"v":0.000513966540475725,"d":"5.14E-04"},{"v":0.0449793,"d":"0.04"}]
[null,2,"SLC2A5","P22732",1,{"v":9097648,"d":"9,097,648"},{"v":9129595,"d":"9,129,595"},{"v":9092343,"d":"9,092,343"},{"v":1.73847e-07,"d":"1.74E-07"},{"v":1.43545E-3,"d":"1.44E-03"},{"v":0.0180289810133511,"d":"1.80E-02"},{"v":-0.133652,"d":"-0.13"}]
[null,3,"PIK3CD","O00329",1,{"v":9770514,"d":"9,770,514"},{"v":9787101,"d":"9,787,101"},{"v":9743729,"d":"9,743,729"},{"v":1.41433e-07,"d":"1.41E-07"},{"v":1.69794E-3,"d":"1.70E-03"},{"v":0.0206285043060433,"d":"2.06E-02"},{"v":0.0549415,"d":"0.05"}]
[null,4,"PGD","P52209",1,{"v":10459175,"d":"10,459,175"},{"v":10479803,"d":"10,479,803"},{"v":10227032,"d":"10,227,032"},{"v":4.70444e-08,"d":"4.70E-08"},{"v":0.00437359,"d":"4.37E-03"},{"v":0.0451337179130996,"d":"4.51E-02"},{"v":-0.0855332,"d":"-0.09"}]
[null,5,"MTHFR","P42898",1,{"v":11850740,"d":"11,850,740"},{"v":11863173,"d":"11,863,173"},{"v":11856378,"d":"11,856,378"},{"v":5.84038e-16,"d":"5.84E-16"},{"v":1.98101E-11,"d":"1.98E-11"},{"v":9.54896716289314e-10,"d":"9.55E-10"},{"v":-0.130908,"d":"-0.13"}]
[null,6,"AGMAT","Q9BSE5",1,{"v":15900149,"d":"15,900,149"},{"v":15911462,"d":"15,911,462"},{"v":15940680,"d":"15,940,680"},{"v":3.9211E-10,"d":"3.92E-10"},{"v":2.25705e-06,"d":"2.26E-06"},{"v":5.24144962404551e-05,"d":"5.24E-05"},{"v":-0.181031,"d":"-0.18"}]
[null,7,"CROCCP3","Q8IVE0",1,{"v":17266392,"d":"17,266,392"},{"v":17272759,"d":"17,272,759"},{"v":16759616,"d":"16,759,616"},{"v":1.70421E-6,"d":"1.70E-06"},{"v":0.00423831,"d":"4.24E-03"},{"v":0.0441059739609607,"d":"4.41E-02"},{"v":0.0814803,"d":"0.08"}]
[null,8,"ALDH4A1","P30038",1,{"v":19199342,"d":"19,199,342"},{"v":19229017,"d":"19,229,017"},{"v":19220907,"d":"19,220,907"},{"v":4.2049e-12,"d":"4.20E-12"},{"v":4.5179e-08,"d":"4.52E-08"},{"v":1.37973354394988E-6,"d":"1.38E-06"},{"v":0.34631,"d":"0.35"}]
[null,9,"MUL1","Q969V5",1,{"v":20827186,"d":"20,827,186"},{"v":20834517,"d":"20,834,517"},{"v":20763601,"d":"20,763,601"},{"v":2.26044e-07,"d":"2.26E-07"},{"v":1.86762E-3,"d":"1.87E-03"},{"v":0.0222950974371879,"d":"2.23E-02"},{"v":-0.270097,"d":"-0.27"}]
[null,10,"C1QB","P02746",1,{"v":22985950,"d":"22,985,950"},{"v":22987876,"d":"22,987,876"},{"v":22976159,"d":"22,976,159"},{"v":5.84067e-07,"d":"5.84E-07"},{"v":0.00430985,"d":"4.31E-03"},{"v":0.0446894659178086,"d":"4.47E-02"},{"v":0.667164,"d":"0.67"}]
[null,11,"HMGCL","P35914",1,{"v":24128956,"d":"24,128,956"},{"v":24151905,"d":"24,151,905"},{"v":24129126,"d":"24,129,126"},{"v":2.97556e-12,"d":"2.98E-12"},{"v":7.48045E-8,"d":"7.48E-08"},{"v":2.16580059344119e-06,"d":"2.17E-06"},{"v":0.0771398,"d":"0.08"}]
[null,12,"RPS6KA1","Q15418",1,{"v":26856412,"d":"26,856,412"},{"v":26900689,"d":"26,900,689"},{"v":26826513,"d":"26,826,513"},{"v":2.54552e-06,"d":"2.55E-06"},{"v":0.00439692,"d":"4.40E-03"},{"v":0.0452764254629206,"d":"4.53E-02"},{"v":-0.0403403,"d":"-0.04"}]
[null,13,"RPA2","P15927",1,{"v":28218677,"d":"28,218,677"},{"v":28240954,"d":"28,240,954"},{"v":28241083,"d":"28,241,083"},{"v":3.21556e-16,"d":"3.22E-16"},{"v":7.3072e-11,"d":"7.31E-11"},{"v":3.19420133821324E-9,"d":"3.19E-09"},{"v":0.228508,"d":"0.23"}]
[null,14,"RPA2","P15927-3",1,{"v":28218677,"d":"28,218,677"},{"v":28240954,"d":"28,240,954"},{"v":28241083,"d":"28,241,083"},{"v":1.24328e-16,"d":"1.24E-16"},{"v":6.62739e-11,"d":"6.63E-11"},{"v":2.91130663851596e-09,"d":"2.91E-09"},{"v":0.22909,"d":"0.23"}]
[null,15,"MECR","Q9BV79",1,{"v":29520537,"d":"29,520,537"},{"v":29557418,"d":"29,557,418"},{"v":29228831,"d":"29,228,831"},{"v":9.48156e-08,"d":"9.48E-08"},{"v":2.65831E-5,"d":"2.66E-05"},{"v":0.000504369977648006,"d":"5.04E-04"},{"v":0.0955631,"d":"0.10"}]
[null,16,"PET112","D6REA0",1,{"v":31404354,"d":"31,404,354"},{"v":31538838,"d":"31,538,838"},{"v":30819446,"d":"30,819,446"},{"v":1.97593E-6,"d":"1.98E-06"},{"v":0.0046792,"d":"4.68E-03"},{"v":0.0475246090472589,"d":"4.75E-02"},{"v":-0.0962239,"d":"-0.10"}]
[null,17,"MARCKSL1","P49006",1,{"v":32800201,"d":"32,800,201"},{"v":32801634,"d":"32,801,634"},{"v":33196120,"d":"33,196,120"},{"v":5.18833e-06,"d":"5.19E-06"},{"v":4.75393E-3,"d":"4.75E-03"},{"v":0.0480868791385282,"d":"4.81E-02"},{"v":-0.198647,"d":"-0.20"}]
[null,18,"NT5C1A","Q9BXI3",1,{"v":40124796,"d":"40,124,796"},{"v":40137710,"d":"40,137,710"},{"v":40149875,"d":"40,149,875"},{"v":3.73302e-07,"d":"3.73E-07"},{"v":1.38153E-3,"d":"1.38E-03"},{"v":0.017425384377151,"d":"1.74E-02"},{"v":0.0861086,"d":"0.09"}]
[null,19,"HYI","Q5T013",1,{"v":43916912,"d":"43,916,912"},{"v":43919464,"d":"43,919,464"},{"v":43919081,"d":"43,919,081"},{"v":1.75882E-13,"d":"1.76E-13"},{"v":1.61088e-07,"d":"1.61E-07"},{"v":4.4199900226836e-06,"d":"4.42E-06"},{"v":-0.403602,"d":"-0.40"}]
[null,20,"HYI","Q5T013-2",1,{"v":43916912,"d":"43,916,912"},{"v":43919464,"d":"43,919,464"},{"v":43788172,"d":"43,788,172"},{"v":8.05307e-07,"d":"8.05E-07"},{"v":0.00155764,"d":"1.56E-03"},{"v":0.0193293506013315,"d":"1.93E-02"},{"v":0.113545,"d":"0.11"}]
[null,21,"AKR1A1","P14550",1,{"v":46027467,"d":"46,027,467"},{"v":46035625,"d":"46,035,625"},{"v":46032311,"d":"46,032,311"},{"v":2.42422e-48,"d":"2.42E-48"},{"v":1.64167e-14,"d":"1.64E-14"},{"v":1.13484777913058E-12,"d":"1.13E-12"},{"v":-0.373485,"d":"-0.37"}]
[null,22,"FAAH","O00519",1,{"v":46860021,"d":"46,860,021"},{"v":46879244,"d":"46,879,244"},{"v":46797692,"d":"46,797,692"},{"v":3.15881e-19,"d":"3.16E-19"},{"v":9.50636e-15,"d":"9.51E-15"},{"v":6.83650336702985e-13,"d":"6.84E-13"},{"v":-0.142975,"d":"-0.14"}]
[null,23,"CMPK1","P30085",1,{"v":47799714,"d":"47,799,714"},{"v":47842414,"d":"47,842,414"},{"v":47834209,"d":"47,834,209"},{"v":4.69006e-13,"d":"4.69E-13"},{"v":1.6226E-7,"d":"1.62E-07"},{"v":4.4384908818502e-06,"d":"4.44E-06"},{"v":-0.161012,"d":"-0.16"}]
[null,24,"RAB3B","P20337",1,{"v":52385602,"d":"52,385,602"},{"v":52442789,"d":"52,442,789"},{"v":52227456,"d":"52,227,456"},{"v":2.10632E-7,"d":"2.11E-07"},{"v":0.000803504,"d":"8.04E-04"},{"v":0.0107747662748159,"d":"1.08E-02"},{"v":-0.330213,"d":"-0.33"}]
[null,25,"COA7","Q96BR5",1,{"v":53153395,"d":"53,153,395"},{"v":53163998,"d":"53,163,998"},{"v":53144641,"d":"53,144,641"},{"v":2.77753e-13,"d":"2.78E-13"},{"v":1.59011E-9,"d":"1.59E-09"},{"v":5.71764185710821e-08,"d":"5.72E-08"},{"v":-0.108158,"d":"-0.11"}]
[null,26,"CPT2","P23786",1,{"v":53662616,"d":"53,662,616"},{"v":53679264,"d":"53,679,264"},{"v":53672028,"d":"53,672,028"},{"v":7.32561e-33,"d":"7.33E-33"},{"v":2.08129E-21,"d":"2.08E-21"},{"v":3.43700606265258e-19,"d":"3.44E-19"},{"v":-0.190484,"d":"-0.19"}]
[null,27,"C1orf123","Q9NWV4",1,{"v":53680334,"d":"53,680,334"},{"v":53686247,"d":"53,686,247"},{"v":53693090,"d":"53,693,090"},{"v":1.60828e-10,"d":"1.61E-10"},{"v":1.55155E-4,"d":"1.55E-04"},{"v":0.00252941395210556,"d":"2.53E-03"},{"v":-0.0967149,"d":"-0.10"}]
[null,28,"ACOT11","Q8WXI4",1,{"v":55013983,"d":"55,013,983"},{"v":55100399,"d":"55,100,399"},{"v":55074840,"d":"55,074,840"},{"v":6.54003e-18,"d":"6.54E-18"},{"v":2.11873E-13,"d":"2.12E-13"},{"v":1.30301397683131e-11,"d":"1.30E-11"},{"v":0.177364,"d":"0.18"}]
[null,29,"ACOT11","Q8WXI4-2",1,{"v":55013983,"d":"55,013,983"},{"v":55100399,"d":"55,100,399"},{"v":55074840,"d":"55,074,840"},{"v":7.01949e-18,"d":"7.02E-18"},{"v":3.02879e-16,"d":"3.03E-16"},{"v":2.81345122293486e-14,"d":"2.81E-14"},{"v":0.168029,"d":"0.17"}]
[null,30,"CACHD1","Q5VU97",1,{"v":64936476,"d":"64,936,476"},{"v":65157241,"d":"65,157,241"},{"v":65098309,"d":"65,098,309"},{"v":7.17882e-07,"d":"7.18E-07"},{"v":0.00312687,"d":"3.13E-03"},{"v":0.034339601972935,"d":"3.43E-02"},{"v":-0.165076,"d":"-0.17"}]
[null,31,"PDE4B","Q07343-3",1,{"v":66378998,"d":"66,378,998"},{"v":66838358,"d":"66,838,358"},{"v":66238907,"d":"66,238,907"},{"v":2.36009e-06,"d":"2.36E-06"},{"v":0.0036811,"d":"3.68E-03"},{"v":0.0394070635820083,"d":"3.94E-02"},{"v":0.0339506,"d":"0.03"}]
[null,32,"LRRC40","Q9H9A6",1,{"v":70611486,"d":"70,611,486"},{"v":70671223,"d":"70,671,223"},{"v":70616830,"d":"70,616,830"},{"v":7.25815e-07,"d":"7.26E-07"},{"v":0.00245686,"d":"2.46E-03"},{"v":0.0281606239470491,"d":"2.82E-02"},{"v":-0.139092,"d":"-0.14"}]
[null,33,"FPGT","O14772",1,{"v":74663963,"d":"74,663,963"},{"v":74671513,"d":"74,671,513"},{"v":74602233,"d":"74,602,233"},{"v":3.53701e-12,"d":"3.54E-12"},{"v":9.51696e-09,"d":"9.52E-09"},{"v":3.21466541251513e-07,"d":"3.21E-07"},{"v":0.0975349,"d":"0.10"}]
[null,34,"CRYZ","Q08257",1,{"v":75171983,"d":"75,171,983"},{"v":75190505,"d":"75,190,505"},{"v":75195243,"d":"75,195,243"},{"v":4.26847e-39,"d":"4.27E-39"},{"v":2.18621e-33,"d":"2.19E-33"},{"v":1.08308073707629E-30,"d":"1.08E-30"},{"v":0.311112,"d":"0.31"}]
[null,35,"AK5","Q9Y6K8",1,{"v":77747999,"d":"77,747,999"},{"v":78024352,"d":"78,024,352"},{"v":78019672,"d":"78,019,672"},{"v":2.93928e-07,"d":"2.94E-07"},{"v":0.000825817,"d":"8.26E-04"},{"v":0.0110003065117767,"d":"1.10E-02"},{"v":0.0515599,"d":"0.05"}]
[null,36,"CCBL2","Q6YP21",1,{"v":89401869,"d":"89,401,869"},{"v":89454033,"d":"89,454,033"},{"v":89402960,"d":"89,402,960"},{"v":7.69142e-74,"d":"7.69E-74"},{"v":2.21953e-68,"d":"2.22E-68"},{"v":1.97925832333274e-64,"d":"1.98E-64"},{"v":-0.413223,"d":"-0.41"}]
[null,37,"EVI5","O60447-2",1,{"v":92979216,"d":"92,979,216"},{"v":93257951,"d":"93,257,951"},{"v":94252029,"d":"94,252,029"},{"v":2.6122e-06,"d":"2.61E-06"},{"v":0.00252741,"d":"2.53E-03"},{"v":0.028784281806687,"d":"2.88E-02"},{"v":-0.172277,"d":"-0.17"}]
[null,38,"AGL","P35573",1,{"v":100316599,"d":"100,316,599"},{"v":100387204,"d":"100,387,204"},{"v":100323540,"d":"100,323,540"},{"v":1.2797e-25,"d":"1.28E-25"},{"v":4.42253e-17,"d":"4.42E-17"},{"v":4.92972009428165e-15,"d":"4.93E-15"},{"v":-0.146668,"d":"-0.15"}]
[null,39,"DBT","P11182",1,{"v":100661814,"d":"100,661,814"},{"v":100715376,"d":"100,715,376"},{"v":100617887,"d":"100,617,887"},{"v":8.5006e-09,"d":"8.50E-09"},{"v":1.42065E-5,"d":"1.42E-05"},{"v":0.000286619864778215,"d":"2.87E-04"},{"v":-0.0710415,"d":"-0.07"}]
[null,40,"SLC25A24","Q6NUK1",1,{"v":108679278,"d":"108,679,278"},{"v":108742760,"d":"108,742,760"},{"v":108737302,"d":"108,737,302"},{"v":2.5847e-17,"d":"2.58E-17"},{"v":5.18383E-11,"d":"5.18E-11"},{"v":2.29983221857803e-09,"d":"2.30E-09"},{"v":-0.132428,"d":"-0.13"}]
[null,41,"CLCC1","Q96S66",1,{"v":109477295,"d":"109,477,295"},{"v":109493059,"d":"109,493,059"},{"v":109509967,"d":"109,509,967"},{"v":1.25911E-8,"d":"1.26E-08"},{"v":1.37136E-4,"d":"1.37E-04"},{"v":0.00225722123272723,"d":"2.26E-03"},{"v":0.0454235,"d":"0.05"}]
[null,42,"GSTM4","Q03013",1,{"v":110199012,"d":"110,199,012"},{"v":110203873,"d":"110,203,873"},{"v":110261567,"d":"110,261,567"},{"v":3.73829e-19,"d":"3.74E-19"},{"v":2.25766e-15,"d":"2.26E-15"},{"v":1.81374830725887E-13,"d":"1.81E-13"},{"v":-0.222426,"d":"-0.22"}]
[null,43,"GSTM2","P28161",1,{"v":110210738,"d":"110,210,738"},{"v":110217455,"d":"110,217,455"},{"v":110261567,"d":"110,261,567"},{"v":1.49825E-15,"d":"1.50E-15"},{"v":1.72312e-09,"d":"1.72E-09"},{"v":6.17102970025497e-08,"d":"6.17E-08"},{"v":-0.118915,"d":"-0.12"}]
[null,44,"GSTM1","P09488",1,{"v":110230496,"d":"110,230,496"},{"v":110235914,"d":"110,235,914"},{"v":110229787,"d":"110,229,787"},{"v":2.46774e-20,"d":"2.47E-20"},{"v":2.35326e-15,"d":"2.35E-15"},{"v":1.873671067574e-13,"d":"1.87E-13"},{"v":0.303271,"d":"0.30"}]
[null,45,"GSTM1","P09488-2",1,{"v":110230496,"d":"110,230,496"},{"v":110235914,"d":"110,235,914"},{"v":110229787,"d":"110,229,787"},{"v":2.10205E-17,"d":"2.10E-17"},{"v":6.52001e-14,"d":"6.52E-14"},{"v":4.27514465195226e-12,"d":"4.28E-12"},{"v":0.287787,"d":"0.29"}]
[null,46,"GSTM5","P46439",1,{"v":110254935,"d":"110,254,935"},{"v":110260045,"d":"110,260,045"},{"v":110259016,"d":"110,259,016"},{"v":8.6287e-28,"d":"8.63E-28"},{"v":1.89543E-23,"d":"1.90E-23"},{"v":3.52134010709717e-21,"d":"3.52E-21"},{"v":-0.326027,"d":"-0.33"}]
[null,47,"GSTM3","P21266",1,{"v":110279696,"d":"110,279,696"},{"v":110282909,"d":"110,282,909"},{"v":110266754,"d":"110,266,754"},{"v":1.83949E-27,"d":"1.84E-27"},{"v":5.32188E-24,"d":"5.32E-24"},{"v":1.10366706441601e-21,"d":"1.10E-21"},{"v":0.284319,"d":"0.28"}]
[null,48,"SYT6","Q5T7P8",1,{"v":114636411,"d":"114,636,411"},{"v":114696394,"d":"114,696,394"},{"v":114899138,"d":"114,899,138"},{"v":1.53195E-8,"d":"1.53E-08"},{"v":3.19126E-3,"d":"3.19E-03"},{"v":0.0349606295276541,"d":"3.50E-02"},{"v":0.664487,"d":"0.66"}]
[null,49,"PTGFRN","Q9P2B2",1,{"v":117452826,"d":"117,452,826"},{"v":117529586,"d":"117,529,586"},{"v":117507402,"d":"117,507,402"},{"v":5.40833e-07,"d":"5.41E-07"},{"v":3.16702E-3,"d":"3.17E-03"},{"v":0.0347377528419662,"d":"3.47E-02"},{"v":0.0561445,"d":"0.06"}]
[null,50,"CHD1L","Q86WJ1",1,{"v":146714354,"d":"146,714,354"},{"v":146767187,"d":"146,767,187"},{"v":146818579,"d":"146,818,579"},{"v":2.90429e-07,"d":"2.90E-07"},{"v":0.000694957,"d":"6.95E-04"},{"v":0.00946145861778353,"d":"9.46E-03"},{"v":-0.135536,"d":"-0.14"}]
[null,51,"BOLA1","Q9Y3E2",1,{"v":149871613,"d":"149,871,613"},{"v":149872023,"d":"149,872,023"},{"v":149871905,"d":"149,871,905"},{"v":3.50848e-13,"d":"3.51E-13"},{"v":3.11081e-08,"d":"3.11E-08"},{"v":9.69949031420458e-07,"d":"9.70E-07"},{"v":0.243975,"d":"0.24"}]
[null,52,"CA14","Q9ULX7",1,{"v":150230524,"d":"150,230,524"},{"v":150237056,"d":"150,237,056"},{"v":150229450,"d":"150,229,450"},{"v":2.46057e-08,"d":"2.46E-08"},{"v":8.65074e-05,"d":"8.65E-05"},{"v":0.0014892409174167,"d":"1.49E-03"},{"v":-0.222436,"d":"-0.22"}]
[null,53,"FAM63A","Q8N5J2",1,{"v":150969766,"d":"150,969,766"},{"v":150975093,"d":"150,975,093"},{"v":150972959,"d":"150,972,959"},{"v":2.00412e-09,"d":"2.00E-09"},{"v":1.50001e-05,"d":"1.50E-05"},{"v":0.000300590744318665,"d":"3.01E-04"},{"v":-0.479422,"d":"-0.48"}]
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[null,865,"CSDC2","Q9Y534",22,{"v":41967970,"d":"41,967,970"},{"v":41970896,"d":"41,970,896"},{"v":41915329,"d":"41,915,329"},{"v":3.25355e-10,"d":"3.25E-10"},{"v":6.7524e-07,"d":"6.75E-07"},{"v":1.6633783751978e-05,"d":"1.66E-05"},{"v":0.234369,"d":"0.23"}]
[null,866,"CYB5R3","P00387",22,{"v":43015782,"d":"43,015,782"},{"v":43045321,"d":"43,045,321"},{"v":43019562,"d":"43,019,562"},{"v":9.99356e-12,"d":"9.99E-12"},{"v":3.01554E-7,"d":"3.02E-07"},{"v":7.88591651499654e-06,"d":"7.89E-06"},{"v":-0.0790118,"d":"-0.08"}]
[null,867,"CYB5R3","P00387-3",22,{"v":43015782,"d":"43,015,782"},{"v":43045321,"d":"43,045,321"},{"v":43019562,"d":"43,019,562"},{"v":1.28149E-11,"d":"1.28E-11"},{"v":5.10131E-8,"d":"5.10E-08"},{"v":1.54730470414916e-06,"d":"1.55E-06"},{"v":-0.0775776,"d":"-0.08"}]
[null,868,"TTLL12","Q14166",22,{"v":43564017,"d":"43,564,017"},{"v":43583075,"d":"43,583,075"},{"v":43562382,"d":"43,562,382"},{"v":1.62004e-20,"d":"1.62E-20"},{"v":3.6818E-15,"d":"3.68E-15"},{"v":2.85498488608595e-13,"d":"2.85E-13"},{"v":-0.119596,"d":"-0.12"}]
[null,869,"TTC38","Q5R3I4",22,{"v":46663937,"d":"46,663,937"},{"v":46688778,"d":"46,688,778"},{"v":46677003,"d":"46,677,003"},{"v":6.59372e-15,"d":"6.59E-15"},{"v":1.18884e-10,"d":"1.19E-10"},{"v":4.90807418418852E-9,"d":"4.91E-09"},{"v":0.566718,"d":"0.57"}]
[null,870,"MAPK12","P53778",22,{"v":50691833,"d":"50,691,833"},{"v":50699938,"d":"50,699,938"},{"v":50661869,"d":"50,661,869"},{"v":2.24575e-08,"d":"2.25E-08"},{"v":9.30686e-05,"d":"9.31E-05"},{"v":1.59603090944519E-3,"d":"1.60E-03"},{"v":0.0651405,"d":"0.07"}]
[null,871,"SCO2","O43819",22,{"v":50962043,"d":"50,962,043"},{"v":50962840,"d":"50,962,840"},{"v":50963905,"d":"50,963,905"},{"v":3.78421E-17,"d":"3.78E-17"},{"v":9.1522e-12,"d":"9.15E-12"},{"v":4.69048459798855e-10,"d":"4.69E-10"},{"v":-0.228619,"d":"-0.23"}]
[null,872,"TYMP","C9JGI3",22,{"v":50964182,"d":"50,964,182"},{"v":50968461,"d":"50,968,461"},{"v":50957520,"d":"50,957,520"},{"v":4.83471e-08,"d":"4.83E-08"},{"v":0.00234627,"d":"2.35E-03"},{"v":0.0271020503493955,"d":"2.71E-02"},{"v":-0.18073,"d":"-0.18"}]
[null,873,"TYMP","P19971",22,{"v":50964202,"d":"50,964,202"},{"v":50968138,"d":"50,968,138"},{"v":50957520,"d":"50,957,520"},{"v":2.01084E-7,"d":"2.01E-07"},{"v":0.00162978,"d":"1.63E-03"},{"v":0.0199636094511819,"d":"2.00E-02"},{"v":-0.167195,"d":"-0.17"}]
[null,874,"CHKB","Q9Y259",22,{"v":51017613,"d":"51,017,613"},{"v":51021210,"d":"51,021,210"},{"v":50993225,"d":"50,993,225"},{"v":9.33357e-07,"d":"9.33E-07"},{"v":1.56066E-3,"d":"1.56E-03"},{"v":0.0193293506013315,"d":"1.93E-02"},{"v":-0.0582784,"d":"-0.06"}]
[null,875,"ARSA","P15289",22,{"v":51063576,"d":"51,063,576"},{"v":51066201,"d":"51,066,201"},{"v":51145702,"d":"51,145,702"},{"v":6.8706E-10,"d":"6.87E-10"},{"v":6.50688e-05,"d":"6.51E-05"},{"v":0.00114673677743933,"d":"1.15E-03"},{"v":-0.262053,"d":"-0.26"}]
[null,876,"PIR","O00625","X",{"v":15403129,"d":"15,403,129"},{"v":15509380,"d":"15,509,380"},{"v":15650932,"d":"15,650,932"},{"v":6.8903e-07,"d":"6.89E-07"},{"v":3.86905e-05,"d":"3.87E-05"},{"v":0.000709920199422578,"d":"7.10E-04"},{"v":-0.371777,"d":"-0.37"}]
[null,877,"PPEF1","O14829","X",{"v":18725900,"d":"18,725,900"},{"v":18845602,"d":"18,845,602"},{"v":18824596,"d":"18,824,596"},{"v":7.34028e-11,"d":"7.34E-11"},{"v":2.54502e-06,"d":"2.55E-06"},{"v":5.80438087730942e-05,"d":"5.80E-05"},{"v":-0.185341,"d":"-0.19"}]
[null,878,"PPEF1","O14829-3","X",{"v":18725900,"d":"18,725,900"},{"v":18845602,"d":"18,845,602"},{"v":18824596,"d":"18,824,596"},{"v":1.08152e-11,"d":"1.08E-11"},{"v":2.25569e-08,"d":"2.26E-08"},{"v":7.28805753718201e-07,"d":"7.29E-07"},{"v":-0.199999,"d":"-0.20"}]
[null,879,"MAOA","P21397","X",{"v":43515590,"d":"43,515,590"},{"v":43603757,"d":"43,603,757"},{"v":43288940,"d":"43,288,940"},{"v":4.92633e-06,"d":"4.93E-06"},{"v":0.000675202,"d":"6.75E-04"},{"v":0.00923124077661473,"d":"9.23E-03"},{"v":0.0874906,"d":"0.09"}]
[null,880,"HSD17B10","Q99714","X",{"v":53458355,"d":"53,458,355"},{"v":53461292,"d":"53,461,292"},{"v":53488083,"d":"53,488,083"},{"v":5.34143e-06,"d":"5.34E-06"},{"v":0.0043176,"d":"4.32E-03"},{"v":0.0447178293269969,"d":"4.47E-02"},{"v":0.0976461,"d":"0.10"}]
[null,881,"CHM","P24386","X",{"v":85119638,"d":"85,119,638"},{"v":85302536,"d":"85,302,536"},{"v":85283775,"d":"85,283,775"},{"v":7.00166e-08,"d":"7.00E-08"},{"v":4.805e-05,"d":"4.81E-05"},{"v":0.000865624726502871,"d":"8.66E-04"},{"v":-0.20278,"d":"-0.20"}]
[null,882,"EPHB6","F8WCM8","X",{"v":131157331,"d":"131,157,331"},{"v":131209971,"d":"131,209,971"},{"v":130195174,"d":"130,195,174"},{"v":2.21296e-05,"d":"2.21E-05"},{"v":0.00465345,"d":"4.65E-03"},{"v":0.0474541677404509,"d":"4.75E-02"},{"v":-0.100775,"d":"-0.10"}]
[null,883,"TMLHE","Q9NVH6","X",{"v":154721199,"d":"154,721,199"},{"v":154774937,"d":"154,774,937"},{"v":154946000,"d":"154,946,000"},{"v":3.42664e-23,"d":"3.43E-23"},{"v":7.63818e-21,"d":"7.64E-21"},{"v":1.23842200335728e-18,"d":"1.24E-18"},{"v":0.145029,"d":"0.15"}]

{"sheet":"Table S4B","index":4,"n_rows":514,"n_cols":11,"rows_kept":514,"merged":[[0,1,0,10],[1,1,1,10]]}
[null,"Table S4B. Significant trans-acting pQTLs identified in frontal cortex tissue from 268 individuals"]
[null,"A total of 511 trans-acting loci for protein (pQTLs) associated with protein expression at the false discovery rate (FDR) of 5%. "]
[null,"Index","Gene symbol","Protein accession","Protein Chr.","Protein start","Protein end","pQTL Chr.","pQTL pos.","Nominal p","q value"]
[null,1,"GBP2","P32456",1,{"v":89573860,"d":"89,573,860"},{"v":89587649,"d":"89,587,649"},1,{"v":153286366,"d":"153,286,366"},{"v":2.35707E-20,"d":"2.36E-20"},{"v":5.06776679023668e-11,"d":"5.07E-11"}]
[null,2,"GBP1","P32455",1,{"v":89519040,"d":"89,519,040"},{"v":89528917,"d":"89,528,917"},1,{"v":153286366,"d":"153,286,366"},{"v":2.99176e-16,"d":"2.99E-16"},{"v":6.43236814025824e-07,"d":"6.43E-07"}]
[null,3,"FAM76A","Q8TAV0-3",1,{"v":28052591,"d":"28,052,591"},{"v":28087089,"d":"28,087,089"},1,{"v":189675987,"d":"189,675,987"},{"v":3.12987e-15,"d":"3.13E-15"},{"v":6.72930852446388e-06,"d":"6.73E-06"}]
[null,4,"KIF2C","Q99661",1,{"v":45205604,"d":"45,205,604"},{"v":45232848,"d":"45,232,848"},1,{"v":200975123,"d":"200,975,123"},{"v":4.84625e-16,"d":"4.85E-16"},{"v":1.0419573795935e-06,"d":"1.04E-06"}]
[null,5,"FAM114A2","E5RK42",1,{"v":243287730,"d":"243,287,730"},{"v":243418650,"d":"243,418,650"},1,{"v":235360291,"d":"235,360,291"},{"v":3.67657e-14,"d":"3.68E-14"},{"v":7.90472889985468e-05,"d":"7.90E-05"}]
[null,6,"ARPP21","Q9UBL0",3,{"v":35723243,"d":"35,723,243"},{"v":35835447,"d":"35,835,447"},1,{"v":59517126,"d":"59,517,126"},{"v":9.38413e-15,"d":"9.38E-15"},{"v":2.0176143419272119E-5,"d":"2.02E-05"}]
[null,7,"NSG1","P42857",4,{"v":4389356,"d":"4,389,356"},{"v":4419159,"d":"4,419,159"},1,{"v":181743133,"d":"181,743,133"},{"v":1.84786E-16,"d":"1.85E-16"},{"v":3.97295096921464E-7,"d":"3.97E-07"}]
[null,8,"RCHY1","Q96PM5",4,{"v":76407750,"d":"76,407,750"},{"v":76439496,"d":"76,439,496"},1,{"v":207477830,"d":"207,477,830"},{"v":6.86342e-15,"d":"6.86E-15"},{"v":1.4756546026824079E-5,"d":"1.48E-05"}]
[null,9,"SRFBP1","Q8NEF9",5,{"v":121297727,"d":"121,297,727"},{"v":121362818,"d":"121,362,818"},1,{"v":11600705,"d":"11,600,705"},{"v":1.02282E-13,"d":"1.02E-13"},{"v":0.000219909176578968,"d":"2.20E-04"}]
[null,10,"GABRG2","P18507",5,{"v":161495005,"d":"161,495,005"},{"v":161580371,"d":"161,580,371"},1,{"v":181743133,"d":"181,743,133"},{"v":1.60567E-26,"d":"1.61E-26"},{"v":3.45223565786308e-17,"d":"3.45E-17"}]
[null,11,"GABRG2","P18507-2",5,{"v":161495005,"d":"161,495,005"},{"v":161580371,"d":"161,580,371"},1,{"v":181743133,"d":"181,743,133"},{"v":1.12389e-20,"d":"1.12E-20"},{"v":2.4163951082823604E-11,"d":"2.42E-11"}]
[null,12,"SNX14","Q9Y5W7",6,{"v":86215687,"d":"86,215,687"},{"v":86303436,"d":"86,303,436"},1,{"v":7111434,"d":"7,111,434"},{"v":1.83987e-19,"d":"1.84E-19"},{"v":3.95577224450388E-10,"d":"3.96E-10"}]
[null,13,"GRM4","Q14833-2",6,{"v":33990600,"d":"33,990,600"},{"v":34101273,"d":"34,101,273"},1,{"v":78008499,"d":"78,008,499"},{"v":5.73649e-15,"d":"5.74E-15"},{"v":1.233361483304476E-5,"d":"1.23E-05"}]
[null,14,"SNX3","O60493-3",6,{"v":108533355,"d":"108,533,355"},{"v":108582125,"d":"108,582,125"},1,{"v":159328719,"d":"159,328,719"},{"v":7.68478e-15,"d":"7.68E-15"},{"v":1.6522493126752718E-5,"d":"1.65E-05"}]
[null,15,"NA","F8VP50",8,{"v":21906506,"d":"21,906,506"},{"v":21940038,"d":"21,940,038"},1,{"v":98963497,"d":"98,963,497"},{"v":3.06378e-16,"d":"3.06E-16"},{"v":6.58721316574872e-07,"d":"6.59E-07"}]
[null,16,"MTBP","Q96DY7",8,{"v":121457710,"d":"121,457,710"},{"v":121535573,"d":"121,535,573"},1,{"v":167193696,"d":"167,193,696"},{"v":1.49579E-17,"d":"1.50E-17"},{"v":3.21599056759796e-08,"d":"3.22E-08"}]
[null,17,"MADD","C9J6B0",8,{"v":104512924,"d":"104,512,924"},{"v":105268322,"d":"105,268,322"},1,{"v":209961286,"d":"209,961,286"},{"v":5.60127e-23,"d":"5.60E-23"},{"v":1.2042888030117477E-13,"d":"1.20E-13"}]
[null,18,"LPAR1","Q92633",9,{"v":113637703,"d":"113,637,703"},{"v":113734397,"d":"113,734,397"},1,{"v":59517126,"d":"59,517,126"},{"v":1.40025e-18,"d":"1.40E-18"},{"v":3.0105768806309998E-9,"d":"3.01E-09"}]
[null,19,"NFX1","Q12986-3",9,{"v":33290570,"d":"33,290,570"},{"v":33369973,"d":"33,369,973"},1,{"v":207477830,"d":"207,477,830"},{"v":6.66213e-14,"d":"6.66E-14"},{"v":1.4323766865744121E-4,"d":"1.43E-04"}]
[null,20,"LRSAM1","Q6UWE0",9,{"v":130216806,"d":"130,216,806"},{"v":130265175,"d":"130,265,175"},1,{"v":210100402,"d":"210,100,402"},{"v":6.96332E-18,"d":"6.96E-18"},{"v":1.4971333836411679E-8,"d":"1.50E-08"}]
[null,21,"IDI2","Q9BXS1",10,{"v":1065459,"d":"1,065,459"},{"v":1070663,"d":"1,070,663"},1,{"v":159328719,"d":"159,328,719"},{"v":5.89267e-14,"d":"5.89E-14"},{"v":1.2669406225451079E-4,"d":"1.27E-04"}]
[null,22,"SHF","H0YLM1",11,{"v":16798844,"d":"16,798,844"},{"v":17035961,"d":"17,035,961"},1,{"v":14212675,"d":"14,212,675"},{"v":5.33625e-17,"d":"5.34E-17"},{"v":1.1473087576695E-7,"d":"1.15E-07"}]
[null,23,"KBTBD4","Q9NVX7",11,{"v":47594484,"d":"47,594,484"},{"v":47599551,"d":"47,599,551"},1,{"v":83847705,"d":"83,847,705"},{"v":1.28479E-13,"d":"1.28E-13"},{"v":2.7623346334339596E-4,"d":"2.76E-04"}]
[null,24,"DDB2","Q92466",11,{"v":47236687,"d":"47,236,687"},{"v":47260397,"d":"47,260,397"},1,{"v":167257592,"d":"167,257,592"},{"v":1.82405e-18,"d":"1.82E-18"},{"v":3.9217587995822005E-9,"d":"3.92E-09"}]
[null,25,"NAA25","Q14CX7",12,{"v":112467337,"d":"112,467,337"},{"v":112546577,"d":"112,546,577"},1,{"v":1252851,"d":"1,252,851"},{"v":5.71529e-16,"d":"5.72E-16"},{"v":1.228803423681596E-6,"d":"1.23E-06"}]
[null,26,"ATN1","P54259",12,{"v":7043164,"d":"7,043,164"},{"v":7050940,"d":"7,050,940"},1,{"v":14212675,"d":"14,212,675"},{"v":3.69089e-18,"d":"3.69E-18"},{"v":7.93551730259036e-09,"d":"7.94E-09"}]
[null,27,"POLR1D","Q9Y2S0",13,{"v":28196120,"d":"28,196,120"},{"v":28197384,"d":"28,197,384"},1,{"v":188515185,"d":"188,515,185"},{"v":6.69461e-18,"d":"6.69E-18"},{"v":1.439359977921164E-8,"d":"1.44E-08"}]
[null,28,"IPO4","Q8TEX9",14,{"v":24649650,"d":"24,649,650"},{"v":24657993,"d":"24,657,993"},1,{"v":207477830,"d":"207,477,830"},{"v":1.89682e-20,"d":"1.90E-20"},{"v":4.07821634616568e-11,"d":"4.08E-11"}]
[null,29,"SUPT6H","Q7KZ85-2",17,{"v":27000419,"d":"27,000,419"},{"v":27028640,"d":"27,028,640"},1,{"v":169657337,"d":"169,657,337"},{"v":4.83137e-16,"d":"4.83E-16"},{"v":1.0387581377449881E-6,"d":"1.04E-06"}]
[null,30,"CCDC144CP","Q8IYA2",17,{"v":16593714,"d":"16,593,714"},{"v":16615130,"d":"16,615,130"},1,{"v":228683774,"d":"228,683,774"},{"v":3.45312e-13,"d":"3.45E-13"},{"v":0.000742430511554688,"d":"7.42E-04"}]
[null,31,"MBD1","Q9UIS9",18,{"v":47797873,"d":"47,797,873"},{"v":47806362,"d":"47,806,362"},1,{"v":1252851,"d":"1,252,851"},{"v":2.47173e-14,"d":"2.47E-14"},{"v":5.31428901493452e-05,"d":"5.31E-05"}]
[null,32,"FHOD3","Q2V2M9",18,{"v":33877798,"d":"33,877,798"},{"v":34359490,"d":"34,359,490"},1,{"v":22306094,"d":"22,306,094"},{"v":4.45239e-15,"d":"4.45E-15"},{"v":9.5727637190163582E-6,"d":"9.57E-06"}]
[null,33,"FHOD3","Q2V2M9-4",18,{"v":33877798,"d":"33,877,798"},{"v":34359490,"d":"34,359,490"},1,{"v":22306094,"d":"22,306,094"},{"v":5.63055E-15,"d":"5.63E-15"},{"v":1.21058408535882e-05,"d":"1.21E-05"}]
[null,34,"ARHGEF7","C9JDI6",19,{"v":39138289,"d":"39,138,289"},{"v":39222229,"d":"39,222,229"},1,{"v":78008499,"d":"78,008,499"},{"v":4.71978e-14,"d":"4.72E-14"},{"v":1.014765973909272E-4,"d":"1.01E-04"}]
[null,35,"BABAM1","Q9NWV8",19,{"v":17379615,"d":"17,379,615"},{"v":17389854,"d":"17,389,854"},1,{"v":168274171,"d":"168,274,171"},{"v":2.51773e-17,"d":"2.52E-17"},{"v":5.4131903086385195E-8,"d":"5.41E-08"}]
[null,36,"ZNF337","Q9Y3M9",20,{"v":25655670,"d":"25,655,670"},{"v":25667053,"d":"25,667,053"},1,{"v":168274171,"d":"168,274,171"},{"v":6.73685e-17,"d":"6.74E-17"},{"v":1.4484416967169398E-7,"d":"1.45E-07"}]
[null,37,"NDUFV3","P56181-2",21,{"v":44313443,"d":"44,313,443"},{"v":44329128,"d":"44,329,128"},1,{"v":248742829,"d":"248,742,829"},{"v":5.62687e-14,"d":"5.63E-14"},{"v":1.2097928750091879E-4,"d":"1.21E-04"}]
[null,38,"FGD1","P98174","X",{"v":54472544,"d":"54,472,544"},{"v":54521865,"d":"54,521,865"},1,{"v":104783671,"d":"104,783,671"},{"v":1.28264E-14,"d":"1.28E-14"},{"v":2.75771207296736E-5,"d":"2.76E-05"}]
[null,39,"ZC4H2","Q9NQZ6","X",{"v":64137665,"d":"64,137,665"},{"v":64196257,"d":"64,196,257"},1,{"v":209961286,"d":"209,961,286"},{"v":9.43424e-16,"d":"9.43E-16"},{"v":2.0283881328565757E-6,"d":"2.03E-06"}]
[null,40,"DMTN","B4DI75",1,{"v":50902700,"d":"50,902,700"},{"v":51425939,"d":"51,425,939"},2,{"v":978906,"d":"978,906"},{"v":6.15921E-40,"d":"6.16E-40"},{"v":1.324247472162204E-30,"d":"1.32E-30"}]
[null,41,"CEP170","Q5SW79-2",1,{"v":243289753,"d":"243,289,753"},{"v":243388582,"d":"243,388,582"},2,{"v":978906,"d":"978,906"},{"v":5.69268e-22,"d":"5.69E-22"},{"v":1.2239422100932322E-12,"d":"1.22E-12"}]
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[null,483,"AP3S2","P59780",15,{"v":90378749,"d":"90,378,749"},{"v":90437181,"d":"90,437,181"},19,{"v":53506807,"d":"53,506,807"},{"v":2.63647e-13,"d":"2.64E-13"},{"v":5.6684846480822794E-4,"d":"5.67E-04"}]
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[null,486,"C1orf123","B1ARP7",17,{"v":40271692,"d":"40,271,692"},{"v":40306934,"d":"40,306,934"},19,{"v":53506807,"d":"53,506,807"},{"v":6.62301E-17,"d":"6.62E-17"},{"v":1.423965776553324E-7,"d":"1.42E-07"}]
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[null,497,"BMP2K","Q9NSY1",4,{"v":79697697,"d":"79,697,697"},{"v":79833184,"d":"79,833,184"},21,{"v":39960651,"d":"39,960,651"},{"v":3.9167e-15,"d":"3.92E-15"},{"v":8.4210151532708e-06,"d":"8.42E-06"}]
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{"sheet":"Table S5A","index":5,"n_rows":9963,"n_cols":12,"rows_kept":4500,"cut":true,"merged":[[0,1,0,8],[1,1,1,11]],"bounds":{"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0}}
[null,"Table S5A. Significent cis-eQTL of human brain cortex tissues"]
[null,"A total of 9,812 cis-eQTLs, corresponding to 9,960 genes were identified at the genome-wide FDR of 5%.  The analysis was performed using normalized expression of 11,792 genes from 416 frontal cortical samples. The linkage analysis was conducted using the QTLtools."]
[null,"Index","Gene symbol","Ensembl ID","Gene Chr.","Gene start","Gene end","eQTL pos.","Nominal p","Beta p","q value","Slope"]
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[null,10,"HES4","ENSG00000188290",1,{"v":934343,"d":"934,343"},{"v":935552,"d":"935,552"},{"v":916549,"d":"916,549"},{"v":2.47635e-05,"d":"2.48E-05"},{"v":0.053409,"d":"5.34E-02"},{"v":0.0302510442992083,"d":"3.03E-02"},{"v":0.133257,"d":"0.13"}]
[null,11,"AGRN","ENSG00000188157",1,{"v":955504,"d":"955,504"},{"v":991496,"d":"991,496"},{"v":970215,"d":"970,215"},{"v":2.13147e-09,"d":"2.13E-09"},{"v":3.41724e-06,"d":"3.42E-06"},{"v":3.92333209245059e-06,"d":"3.92E-06"},{"v":-0.0626595,"d":"-0.06"}]
[null,12,"RP11-465B22.3","ENSG00000217801",1,{"v":995115,"d":"995,115"},{"v":1004735,"d":"1,004,735"},{"v":998582,"d":"998,582"},{"v":1.11403e-34,"d":"1.11E-34"},{"v":6.67566e-20,"d":"6.68E-20"},{"v":2.40464102987281e-19,"d":"2.40E-19"},{"v":0.45814,"d":"0.46"}]
[null,13,"C1orf159","ENSG00000131591",1,{"v":1017199,"d":"1,017,199"},{"v":1051741,"d":"1,051,741"},{"v":1033596,"d":"1,033,596"},{"v":6.39738e-21,"d":"6.40E-21"},{"v":1.0256E-16,"d":"1.03E-16"},{"v":3.04338232142409e-16,"d":"3.04E-16"},{"v":-0.166505,"d":"-0.17"}]
[null,14,"RP5-902P8.10","ENSG00000230415",1,{"v":1210604,"d":"1,210,604"},{"v":1215800,"d":"1,215,800"},{"v":1215712,"d":"1,215,712"},{"v":4.70491e-06,"d":"4.70E-06"},{"v":0.015046,"d":"1.50E-02"},{"v":0.00995174502809235,"d":"9.95E-03"},{"v":0.38707,"d":"0.39"}]
[null,15,"SCNN1D","ENSG00000162572",1,{"v":1215817,"d":"1,215,817"},{"v":1227409,"d":"1,227,409"},{"v":1207215,"d":"1,207,215"},{"v":1.78335e-18,"d":"1.78E-18"},{"v":1.27973E-14,"d":"1.28E-14"},{"v":3.21440509572898e-14,"d":"3.21E-14"},{"v":0.30979,"d":"0.31"}]
[null,16,"CPSF3L","ENSG00000127054",1,{"v":1246966,"d":"1,246,966"},{"v":1260071,"d":"1,260,071"},{"v":1337837,"d":"1,337,837"},{"v":5.28978e-07,"d":"5.29E-07"},{"v":1.39894E-3,"d":"1.40E-03"},{"v":1.12524150571747E-3,"d":"1.13E-03"},{"v":0.0370232,"d":"0.04"}]
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[null,1929,"TMEM110","ENSG00000213533",3,{"v":52870236,"d":"52,870,236"},{"v":52931612,"d":"52,931,612"},{"v":52874288,"d":"52,874,288"},{"v":1.56845e-23,"d":"1.57E-23"},{"v":1.55177e-20,"d":"1.55E-20"},{"v":5.82662171885837e-20,"d":"5.83E-20"},{"v":0.135364,"d":"0.14"}]
[null,1930,"SFMBT1","ENSG00000163935",3,{"v":52937589,"d":"52,937,589"},{"v":53080766,"d":"53,080,766"},{"v":53022076,"d":"53,022,076"},{"v":2.14364e-14,"d":"2.14E-14"},{"v":2.15378E-9,"d":"2.15E-09"},{"v":3.45505990273784e-09,"d":"3.46E-09"},{"v":0.0737539,"d":"0.07"}]
[null,1931,"RFT1","ENSG00000163933",3,{"v":53122500,"d":"53,122,500"},{"v":53164478,"d":"53,164,478"},{"v":53111704,"d":"53,111,704"},{"v":6.62178e-15,"d":"6.62E-15"},{"v":1.64425e-11,"d":"1.64E-11"},{"v":3.19434609851814e-11,"d":"3.19E-11"},{"v":0.0615184,"d":"0.06"}]
[null,1932,"PRKCD","ENSG00000163932",3,{"v":53190026,"d":"53,190,026"},{"v":53226733,"d":"53,226,733"},{"v":53193548,"d":"53,193,548"},{"v":3.36198e-23,"d":"3.36E-23"},{"v":2.38231E-16,"d":"2.38E-16"},{"v":6.83247823836029e-16,"d":"6.83E-16"},{"v":-0.327722,"d":"-0.33"}]
[null,1933,"TKT","ENSG00000163931",3,{"v":53258724,"d":"53,258,724"},{"v":53290068,"d":"53,290,068"},{"v":53250286,"d":"53,250,286"},{"v":4.60371E-12,"d":"4.60E-12"},{"v":1.10798E-8,"d":"1.11E-08"},{"v":1.66849830922198E-8,"d":"1.67E-08"},{"v":-0.0507391,"d":"-0.05"}]
[null,1934,"CHDH","ENSG00000016391",3,{"v":53846363,"d":"53,846,363"},{"v":53880417,"d":"53,880,417"},{"v":53856653,"d":"53,856,653"},{"v":2.46207E-7,"d":"2.46E-07"},{"v":0.000993483,"d":"9.93E-04"},{"v":0.000818726565678931,"d":"8.19E-04"},{"v":0.0667179,"d":"0.07"}]
[null,1935,"IL17RB","ENSG00000056736",3,{"v":53880608,"d":"53,880,608"},{"v":53899827,"d":"53,899,827"},{"v":53892553,"d":"53,892,553"},{"v":4.57313e-12,"d":"4.57E-12"},{"v":4.12996E-7,"d":"4.13E-07"},{"v":5.28630546510175E-7,"d":"5.29E-07"},{"v":0.126585,"d":"0.13"}]
[null,1936,"RP11-884K10.7","ENSG00000271976",3,{"v":53893022,"d":"53,893,022"},{"v":53895603,"d":"53,895,603"},{"v":53959904,"d":"53,959,904"},{"v":1.36026e-18,"d":"1.36E-18"},{"v":1.59193E-15,"d":"1.59E-15"},{"v":4.27225929088541e-15,"d":"4.27E-15"},{"v":-0.100982,"d":"-0.10"}]
[null,1937,"ACTR8","ENSG00000113812",3,{"v":53901094,"d":"53,901,094"},{"v":53916229,"d":"53,916,229"},{"v":53921223,"d":"53,921,223"},{"v":8.83782e-98,"d":"8.84E-98"},{"v":1.41769e-68,"d":"1.42E-68"},{"v":6.2240200564044e-67,"d":"6.22E-67"},{"v":-0.196884,"d":"-0.20"}]
[null,1938,"CACNA2D3","ENSG00000157445",3,{"v":54156575,"d":"54,156,575"},{"v":55108584,"d":"55,108,584"},{"v":55118455,"d":"55,118,455"},{"v":8.79102e-09,"d":"8.79E-09"},{"v":5.24334e-05,"d":"5.24E-05"},{"v":5.19840362725885e-05,"d":"5.20E-05"},{"v":-0.0416788,"d":"-0.04"}]
[null,1939,"WNT5A","ENSG00000114251",3,{"v":55499744,"d":"55,499,744"},{"v":55523973,"d":"55,523,973"},{"v":55793077,"d":"55,793,077"},{"v":2.90416e-06,"d":"2.90E-06"},{"v":0.0173527,"d":"1.74E-02"},{"v":0.0113257741100926,"d":"1.13E-02"},{"v":0.072307,"d":"0.07"}]
[null,1940,"ERC2","ENSG00000187672",3,{"v":55542337,"d":"55,542,337"},{"v":56502391,"d":"56,502,391"},{"v":56090387,"d":"56,090,387"},{"v":1.22121e-07,"d":"1.22E-07"},{"v":0.0010657,"d":"1.07E-03"},{"v":0.000873894057130903,"d":"8.74E-04"},{"v":-0.0350853,"d":"-0.04"}]
[null,1941,"CCDC66","ENSG00000180376",3,{"v":56591190,"d":"56,591,190"},{"v":56655846,"d":"56,655,846"},{"v":56579538,"d":"56,579,538"},{"v":5.26414e-40,"d":"5.26E-40"},{"v":4.40345E-37,"d":"4.40E-37"},{"v":4.28385454337684e-36,"d":"4.28E-36"},{"v":-0.0905383,"d":"-0.09"}]
[null,1942,"FAM208A","ENSG00000163946",3,{"v":56654162,"d":"56,654,162"},{"v":56717265,"d":"56,717,265"},{"v":56566474,"d":"56,566,474"},{"v":1.57481e-07,"d":"1.57E-07"},{"v":0.000184559,"d":"1.85E-04"},{"v":1.70137360088405E-4,"d":"1.70E-04"},{"v":0.0460958,"d":"0.05"}]
[null,1943,"ARHGEF3","ENSG00000163947",3,{"v":56761447,"d":"56,761,447"},{"v":57113357,"d":"57,113,357"},{"v":56762967,"d":"56,762,967"},{"v":3.07193e-07,"d":"3.07E-07"},{"v":6.01091E-4,"d":"6.01E-04"},{"v":0.000513139897574413,"d":"5.13E-04"},{"v":0.0493469,"d":"0.05"}]
[null,1944,"IL17RD","ENSG00000144730",3,{"v":57124011,"d":"57,124,011"},{"v":57204334,"d":"57,204,334"},{"v":57078366,"d":"57,078,366"},{"v":2.41781e-05,"d":"2.42E-05"},{"v":0.0127392,"d":"1.27E-02"},{"v":0.00856157894414661,"d":"8.56E-03"},{"v":0.0483677,"d":"0.05"}]
[null,1945,"APPL1","ENSG00000157500",3,{"v":57261766,"d":"57,261,766"},{"v":57307496,"d":"57,307,496"},{"v":57406129,"d":"57,406,129"},{"v":7.12477e-05,"d":"7.12E-05"},{"v":0.0527704,"d":"5.28E-02"},{"v":0.029954727087855,"d":"3.00E-02"},{"v":0.0145861,"d":"0.01"}]
[null,1946,"DNAH12","ENSG00000174844",3,{"v":57327728,"d":"57,327,728"},{"v":57530071,"d":"57,530,071"},{"v":57533658,"d":"57,533,658"},{"v":1.42598e-12,"d":"1.43E-12"},{"v":2.12947e-05,"d":"2.13E-05"},{"v":2.21601116568147e-05,"d":"2.22E-05"},{"v":-0.34092,"d":"-0.34"}]
[null,1947,"ARF4","ENSG00000168374",3,{"v":57557091,"d":"57,557,091"},{"v":57583947,"d":"57,583,947"},{"v":57596105,"d":"57,596,105"},{"v":3.33459e-11,"d":"3.33E-11"},{"v":1.04628e-06,"d":"1.05E-06"},{"v":1.27444146141776E-6,"d":"1.27E-06"},{"v":0.0490792,"d":"0.05"}]
[null,1948,"SLMAP","ENSG00000163681",3,{"v":57741178,"d":"57,741,178"},{"v":57914895,"d":"57,914,895"},{"v":58050620,"d":"58,050,620"},{"v":1.02194E-6,"d":"1.02E-06"},{"v":0.00171015,"d":"1.71E-03"},{"v":0.0013587552800599,"d":"1.36E-03"},{"v":-0.0211001,"d":"-0.02"}]
[null,1949,"FLNB","ENSG00000136068",3,{"v":57994128,"d":"57,994,128"},{"v":58157982,"d":"58,157,982"},{"v":58155230,"d":"58,155,230"},{"v":3.70346e-09,"d":"3.70E-09"},{"v":0.000120193,"d":"1.20E-04"},{"v":1.13531281808415E-4,"d":"1.14E-04"},{"v":-0.0632571,"d":"-0.06"}]
[null,1950,"ABHD6","ENSG00000163686",3,{"v":58223234,"d":"58,223,234"},{"v":58281420,"d":"58,281,420"},{"v":58267811,"d":"58,267,811"},{"v":1.63968E-8,"d":"1.64E-08"},{"v":0.000117739,"d":"1.18E-04"},{"v":1.11459251611934E-4,"d":"1.11E-04"},{"v":0.0980603,"d":"0.10"}]
[null,1951,"RPP14","ENSG00000163684",3,{"v":58291975,"d":"58,291,975"},{"v":58310422,"d":"58,310,422"},{"v":58410431,"d":"58,410,431"},{"v":2.58408E-12,"d":"2.58E-12"},{"v":1.04142e-07,"d":"1.04E-07"},{"v":1.41667261044543e-07,"d":"1.42E-07"},{"v":0.0485927,"d":"0.05"}]
[null,1952,"PXK","ENSG00000168297",3,{"v":58318608,"d":"58,318,608"},{"v":58411748,"d":"58,411,748"},{"v":58408679,"d":"58,408,679"},{"v":1.32524E-18,"d":"1.33E-18"},{"v":3.77127e-16,"d":"3.77E-16"},{"v":1.06436799634338E-15,"d":"1.06E-15"},{"v":-0.084741,"d":"-0.08"}]
[null,1953,"PDHB","ENSG00000168291",3,{"v":58413358,"d":"58,413,358"},{"v":58419584,"d":"58,419,584"},{"v":58413662,"d":"58,413,662"},{"v":1.91349e-36,"d":"1.91E-36"},{"v":2.96557e-29,"d":"2.97E-29"},{"v":1.8486578412124e-28,"d":"1.85E-28"},{"v":0.0872643,"d":"0.09"}]
[null,1954,"RP11-802O23.3","ENSG00000272182",3,{"v":58413983,"d":"58,413,983"},{"v":58414542,"d":"58,414,542"},{"v":58457736,"d":"58,457,736"},{"v":1.15445E-12,"d":"1.15E-12"},{"v":7.96823e-07,"d":"7.97E-07"},{"v":9.82939323335486E-7,"d":"9.83E-07"},{"v":-0.350095,"d":"-0.35"}]
[null,1955,"KCTD6","ENSG00000168301",3,{"v":58477842,"d":"58,477,842"},{"v":58488087,"d":"58,488,087"},{"v":58428397,"d":"58,428,397"},{"v":1.55866E-17,"d":"1.56E-17"},{"v":6.74808e-14,"d":"6.75E-14"},{"v":1.61069579485825e-13,"d":"1.61E-13"},{"v":0.0656327,"d":"0.07"}]
[null,1956,"FAM107A","ENSG00000168309",3,{"v":58549845,"d":"58,549,845"},{"v":58613337,"d":"58,613,337"},{"v":58560446,"d":"58,560,446"},{"v":2.2749e-05,"d":"2.27E-05"},{"v":0.0271011,"d":"2.71E-02"},{"v":0.0168552431456747,"d":"1.69E-02"},{"v":0.0495734,"d":"0.05"}]
[null,1957,"C3orf67","ENSG00000163689",3,{"v":58703093,"d":"58,703,093"},{"v":59035810,"d":"59,035,810"},{"v":59035425,"d":"59,035,425"},{"v":1.08322E-10,"d":"1.08E-10"},{"v":2.74171e-06,"d":"2.74E-06"},{"v":3.19199043685646e-06,"d":"3.19E-06"},{"v":-0.315678,"d":"-0.32"}]
[null,1958,"PTPRG-AS1","ENSG00000241472",3,{"v":62246541,"d":"62,246,541"},{"v":62355005,"d":"62,355,005"},{"v":62250256,"d":"62,250,256"},{"v":8.10517e-06,"d":"8.11E-06"},{"v":0.0273533,"d":"2.74E-02"},{"v":0.0169997462950485,"d":"1.70E-02"},{"v":0.0748934,"d":"0.07"}]
[null,1959,"C3orf14","ENSG00000114405",3,{"v":62304649,"d":"62,304,649"},{"v":62321888,"d":"62,321,888"},{"v":62305073,"d":"62,305,073"},{"v":6.1655e-05,"d":"6.17E-05"},{"v":0.0879884,"d":"8.80E-02"},{"v":0.0461278863023547,"d":"4.61E-02"},{"v":-0.0300959,"d":"-0.03"}]
[null,1960,"CADPS","ENSG00000163618",3,{"v":62384023,"d":"62,384,023"},{"v":62861054,"d":"62,861,054"},{"v":62670868,"d":"62,670,868"},{"v":3.78036E-6,"d":"3.78E-06"},{"v":0.0232683,"d":"2.33E-02"},{"v":0.0147137634788086,"d":"1.47E-02"},{"v":0.0263966,"d":"0.03"}]
[null,1961,"SYNPR","ENSG00000163630",3,{"v":63213992,"d":"63,213,992"},{"v":63602597,"d":"63,602,597"},{"v":62746495,"d":"62,746,495"},{"v":1.4239e-08,"d":"1.42E-08"},{"v":0.0756769,"d":"7.57E-02"},{"v":0.0406493265644412,"d":"4.06E-02"},{"v":0.302912,"d":"0.30"}]
[null,1962,"THOC7","ENSG00000163634",3,{"v":63819547,"d":"63,819,547"},{"v":63849579,"d":"63,849,579"},{"v":63842629,"d":"63,842,629"},{"v":1.10058e-22,"d":"1.10E-22"},{"v":4.13698e-21,"d":"4.14E-21"},{"v":1.61106920004985e-20,"d":"1.61E-20"},{"v":-0.0781616,"d":"-0.08"}]
[null,1963,"PSMD6-AS2","ENSG00000239653",3,{"v":63989699,"d":"63,989,699"},{"v":63997824,"d":"63,997,824"},{"v":64751449,"d":"64,751,449"},{"v":1.16825E-5,"d":"1.17E-05"},{"v":0.0371804,"d":"3.72E-02"},{"v":0.0221915831136883,"d":"2.22E-02"},{"v":-0.20746,"d":"-0.21"}]
[null,1964,"PSMD6","ENSG00000163636",3,{"v":63996226,"d":"63,996,226"},{"v":64009658,"d":"64,009,658"},{"v":63996262,"d":"63,996,262"},{"v":1.60561e-12,"d":"1.61E-12"},{"v":3.5513e-08,"d":"3.55E-08"},{"v":5.09115269189818e-08,"d":"5.09E-08"},{"v":-0.0492277,"d":"-0.05"}]
[null,1965,"ADAMTS9-AS2","ENSG00000241684",3,{"v":64670586,"d":"64,670,586"},{"v":64997143,"d":"64,997,143"},{"v":65104731,"d":"65,104,731"},{"v":1.63991E-5,"d":"1.64E-05"},{"v":0.0589138,"d":"5.89E-02"},{"v":0.0328823754112582,"d":"3.29E-02"},{"v":-0.0668858,"d":"-0.07"}]
[null,1966,"SLC25A26","ENSG00000144741",3,{"v":66119286,"d":"66,119,286"},{"v":66438540,"d":"66,438,540"},{"v":66288450,"d":"66,288,450"},{"v":1.42384e-65,"d":"1.42E-65"},{"v":9.61023e-49,"d":"9.61E-49"},{"v":1.73816504094767e-47,"d":"1.74E-47"},{"v":-0.18429,"d":"-0.18"}]
[null,1967,"LRIG1","ENSG00000144749",3,{"v":66429222,"d":"66,429,222"},{"v":66551687,"d":"66,551,687"},{"v":66421147,"d":"66,421,147"},{"v":1.06817E-9,"d":"1.07E-09"},{"v":2.71657E-6,"d":"2.72E-06"},{"v":3.16487360771087e-06,"d":"3.16E-06"},{"v":-0.0805881,"d":"-0.08"}]
[null,1968,"SUCLG2","ENSG00000172340",3,{"v":67410885,"d":"67,410,885"},{"v":67705038,"d":"67,705,038"},{"v":67458562,"d":"67,458,562"},{"v":3.40183E-14,"d":"3.40E-14"},{"v":2.08257e-12,"d":"2.08E-12"},{"v":4.36625496842977e-12,"d":"4.37E-12"},{"v":-0.100656,"d":"-0.10"}]
[null,1969,"RP11-81N13.1","ENSG00000241316",3,{"v":67705122,"d":"67,705,122"},{"v":67998137,"d":"67,998,137"},{"v":67699371,"d":"67,699,371"},{"v":2.22582e-52,"d":"2.23E-52"},{"v":6.68443E-41,"d":"6.68E-41"},{"v":8.07887742341225e-40,"d":"8.08E-40"},{"v":-0.363448,"d":"-0.36"}]
[null,1970,"FAM19A1","ENSG00000183662",3,{"v":68053360,"d":"68,053,360"},{"v":68594776,"d":"68,594,776"},{"v":69334653,"d":"69,334,653"},{"v":3.19616e-05,"d":"3.20E-05"},{"v":0.0910601,"d":"9.11E-02"},{"v":0.0474621124034881,"d":"4.75E-02"},{"v":0.211093,"d":"0.21"}]
[null,1971,"EOGT","ENSG00000163378",3,{"v":69024366,"d":"69,024,366"},{"v":69063112,"d":"69,063,112"},{"v":69040601,"d":"69,040,601"},{"v":2.11831E-26,"d":"2.12E-26"},{"v":9.54911e-22,"d":"9.55E-22"},{"v":3.89904120029681e-21,"d":"3.90E-21"},{"v":-0.118559,"d":"-0.12"}]
[null,1972,"TMF1","ENSG00000144747",3,{"v":69068979,"d":"69,068,979"},{"v":69101484,"d":"69,101,484"},{"v":69122337,"d":"69,122,337"},{"v":2.70611e-06,"d":"2.71E-06"},{"v":0.0103354,"d":"1.03E-02"},{"v":0.0070889029051279,"d":"7.09E-03"},{"v":0.0208652,"d":"0.02"}]
[null,1973,"UBA3","ENSG00000144744",3,{"v":69103882,"d":"69,103,882"},{"v":69129559,"d":"69,129,559"},{"v":69235287,"d":"69,235,287"},{"v":3.25965e-05,"d":"3.26E-05"},{"v":0.0499939,"d":"5.00E-02"},{"v":0.0286033210079162,"d":"2.86E-02"},{"v":-0.0579238,"d":"-0.06"}]
[null,1974,"ARL6IP5","ENSG00000144746",3,{"v":69134096,"d":"69,134,096"},{"v":69155217,"d":"69,155,217"},{"v":69154343,"d":"69,154,343"},{"v":6.54348e-15,"d":"6.54E-15"},{"v":6.88763e-10,"d":"6.89E-10"},{"v":1.15353719404062e-09,"d":"1.15E-09"},{"v":0.0405879,"d":"0.04"}]
[null,1975,"FOXP1-IT1","ENSG00000242094",3,{"v":71619407,"d":"71,619,407"},{"v":71623608,"d":"71,623,608"},{"v":71612149,"d":"71,612,149"},{"v":4.07474e-06,"d":"4.07E-06"},{"v":0.00808774,"d":"8.09E-03"},{"v":0.00566373118443126,"d":"5.66E-03"},{"v":0.0779493,"d":"0.08"}]
[null,1976,"EIF4E3","ENSG00000163412",3,{"v":71724568,"d":"71,724,568"},{"v":71803924,"d":"71,803,924"},{"v":71760875,"d":"71,760,875"},{"v":5.45039E-13,"d":"5.45E-13"},{"v":5.23948e-08,"d":"5.24E-08"},{"v":7.37143301149375e-08,"d":"7.37E-08"},{"v":-0.0443075,"d":"-0.04"}]
[null,1977,"GPR27","ENSG00000170837",3,{"v":71803202,"d":"71,803,202"},{"v":71805647,"d":"71,805,647"},{"v":71774791,"d":"71,774,791"},{"v":2.13823E-15,"d":"2.14E-15"},{"v":3.42287e-10,"d":"3.42E-10"},{"v":5.88522093456229e-10,"d":"5.89E-10"},{"v":0.100757,"d":"0.10"}]
[null,1978,"GXYLT2","ENSG00000172986",3,{"v":72937225,"d":"72,937,225"},{"v":73047289,"d":"73,047,289"},{"v":72973781,"d":"72,973,781"},{"v":1.81813e-05,"d":"1.82E-05"},{"v":0.0489735,"d":"4.90E-02"},{"v":0.0281235194832206,"d":"2.81E-02"},{"v":-0.0716715,"d":"-0.07"}]
[null,1979,"PPP4R2","ENSG00000163605",3,{"v":73045937,"d":"73,045,937"},{"v":73118350,"d":"73,118,350"},{"v":73113528,"d":"73,113,528"},{"v":1.30338E-11,"d":"1.30E-11"},{"v":2.63219e-07,"d":"2.63E-07"},{"v":3.43421427641389e-07,"d":"3.43E-07"},{"v":0.0364116,"d":"0.04"}]
[null,1980,"CNTN3","ENSG00000113805",3,{"v":74311720,"d":"74,311,720"},{"v":74570291,"d":"74,570,291"},{"v":74548611,"d":"74,548,611"},{"v":4.1176e-06,"d":"4.12E-06"},{"v":0.00752193,"d":"7.52E-03"},{"v":0.00529638516577625,"d":"5.30E-03"},{"v":0.041942,"d":"0.04"}]
[null,1981,"FAM86DP","ENSG00000244026",3,{"v":75470704,"d":"75,470,704"},{"v":75484261,"d":"75,484,261"},{"v":75410380,"d":"75,410,380"},{"v":1.15866E-35,"d":"1.16E-35"},{"v":1.65131E-6,"d":"1.65E-06"},{"v":1.96540326491428E-6,"d":"1.97E-06"},{"v":-1.42166,"d":"-1.42"}]
[null,1982,"RP11-803B1.8","ENSG00000272690",3,{"v":75484500,"d":"75,484,500"},{"v":75506637,"d":"75,506,637"},{"v":75410380,"d":"75,410,380"},{"v":3.83796e-22,"d":"3.84E-22"},{"v":1.30697E-7,"d":"1.31E-07"},{"v":1.75881041324421e-07,"d":"1.76E-07"},{"v":-1.15228,"d":"-1.15"}]
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[null,1985,"ROBO1","ENSG00000169855",3,{"v":78646391,"d":"78,646,391"},{"v":79816965,"d":"79,816,965"},{"v":79594835,"d":"79,594,835"},{"v":2.19233e-06,"d":"2.19E-06"},{"v":0.0130397,"d":"1.30E-02"},{"v":0.00874180312408785,"d":"8.74E-03"},{"v":0.0330688,"d":"0.03"}]
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[null,9938,"EMD","ENSG00000102119","X",{"v":153607558,"d":"153,607,558"},{"v":153609883,"d":"153,609,883"},{"v":154024384,"d":"154,024,384"},{"v":7.16501e-06,"d":"7.17E-06"},{"v":1.90844E-3,"d":"1.91E-03"},{"v":0.00150512649802849,"d":"1.51E-03"},{"v":0.193972,"d":"0.19"}]
[null,9939,"RPL10","ENSG00000147403","X",{"v":153618316,"d":"153,618,316"},{"v":153637504,"d":"153,637,504"},{"v":153297142,"d":"153,297,142"},{"v":5.41177e-08,"d":"5.41E-08"},{"v":0.000191257,"d":"1.91E-04"},{"v":1.75933077201915E-4,"d":"1.76E-04"},{"v":0.19834,"d":"0.20"}]
[null,9940,"SNORA70","ENSG00000207165","X",{"v":153628623,"d":"153,628,623"},{"v":153628756,"d":"153,628,756"},{"v":153319591,"d":"153,319,591"},{"v":5.90326e-05,"d":"5.90E-05"},{"v":0.0325802,"d":"3.26E-02"},{"v":0.019816623641451,"d":"1.98E-02"},{"v":-0.208196,"d":"-0.21"}]
[null,9941,"DNASE1L1","ENSG00000013563","X",{"v":153629580,"d":"153,629,580"},{"v":153640449,"d":"153,640,449"},{"v":153640406,"d":"153,640,406"},{"v":2.77684e-16,"d":"2.78E-16"},{"v":1.9449e-16,"d":"1.94E-16"},{"v":5.63143700158643e-16,"d":"5.63E-16"},{"v":0.165275,"d":"0.17"}]
[null,9942,"TAZ","ENSG00000102125","X",{"v":153639855,"d":"153,639,855"},{"v":153650065,"d":"153,650,065"},{"v":153640406,"d":"153,640,406"},{"v":7.12505e-11,"d":"7.13E-11"},{"v":4.44483E-7,"d":"4.44E-07"},{"v":5.66252589529136e-07,"d":"5.66E-07"},{"v":-0.087802,"d":"-0.09"}]
[null,9943,"ATP6AP1","ENSG00000071553","X",{"v":153656979,"d":"153,656,979"},{"v":153664862,"d":"153,664,862"},{"v":153314172,"d":"153,314,172"},{"v":7.7946e-08,"d":"7.79E-08"},{"v":0.000154166,"d":"1.54E-04"},{"v":0.000143588168752614,"d":"1.44E-04"},{"v":0.125269,"d":"0.13"}]
[null,9944,"FAM50A","ENSG00000071859","X",{"v":153672474,"d":"153,672,474"},{"v":153679002,"d":"153,679,002"},{"v":153613589,"d":"153,613,589"},{"v":3.16972e-05,"d":"3.17E-05"},{"v":0.00900548,"d":"9.01E-03"},{"v":0.00625101751182709,"d":"6.25E-03"},{"v":0.0721666,"d":"0.07"}]
[null,9945,"PLXNA3","ENSG00000130827","X",{"v":153686622,"d":"153,686,622"},{"v":153701989,"d":"153,701,989"},{"v":153505339,"d":"153,505,339"},{"v":9.11331e-17,"d":"9.11E-17"},{"v":1.63347e-08,"d":"1.63E-08"},{"v":2.4235928824964E-8,"d":"2.42E-08"},{"v":-0.20729,"d":"-0.21"}]
[null,9946,"UBL4A","ENSG00000102178","X",{"v":153712057,"d":"153,712,057"},{"v":153715009,"d":"153,715,009"},{"v":153704796,"d":"153,704,796"},{"v":2.87158e-27,"d":"2.87E-27"},{"v":1.18052e-18,"d":"1.18E-18"},{"v":3.96071622721528e-18,"d":"3.96E-18"},{"v":-0.189092,"d":"-0.19"}]
[null,9947,"FAM3A","ENSG00000071889","X",{"v":153733351,"d":"153,733,351"},{"v":153744566,"d":"153,744,566"},{"v":153750001,"d":"153,750,001"},{"v":7.5951e-12,"d":"7.60E-12"},{"v":1.60368E-7,"d":"1.60E-07"},{"v":2.13848891692359e-07,"d":"2.14E-07"},{"v":-0.115755,"d":"-0.12"}]
[null,9948,"IKBKG","ENSG00000073009","X",{"v":153769415,"d":"153,769,415"},{"v":153796782,"d":"153,796,782"},{"v":153750348,"d":"153,750,348"},{"v":6.67426e-20,"d":"6.67E-20"},{"v":7.53982e-12,"d":"7.54E-12"},{"v":1.50696589574443E-11,"d":"1.51E-11"},{"v":-0.183807,"d":"-0.18"}]
[null,9949,"IKBKGP1","ENSG00000224882","X",{"v":153868252,"d":"153,868,252"},{"v":153876549,"d":"153,876,549"},{"v":153005844,"d":"153,005,844"},{"v":1.39125e-05,"d":"1.39E-05"},{"v":0.021088,"d":"2.11E-02"},{"v":0.0134732834940042,"d":"1.35E-02"},{"v":-1.59673,"d":"-1.60"}]
[null,9950,"F8","ENSG00000185010","X",{"v":154064064,"d":"154,064,064"},{"v":154255215,"d":"154,255,215"},{"v":154004584,"d":"154,004,584"},{"v":9.13611e-05,"d":"9.14E-05"},{"v":0.0443536,"d":"4.44E-02"},{"v":0.0258600009395849,"d":"2.59E-02"},{"v":-0.0729456,"d":"-0.07"}]
[null,9951,"F8A1","ENSG00000197932","X",{"v":154114636,"d":"154,114,636"},{"v":154116335,"d":"154,116,335"},{"v":154428021,"d":"154,428,021"},{"v":2.34313e-17,"d":"2.34E-17"},{"v":0.000994543,"d":"9.95E-04"},{"v":0.000819468636131322,"d":"8.19E-04"},{"v":-0.405308,"d":"-0.41"}]
[null,9952,"FUNDC2","ENSG00000165775","X",{"v":154254256,"d":"154,254,256"},{"v":154288578,"d":"154,288,578"},{"v":154053666,"d":"154,053,666"},{"v":7.2002e-06,"d":"7.20E-06"},{"v":0.0376432,"d":"3.76E-02"},{"v":0.0224209162547515,"d":"2.24E-02"},{"v":-0.0291805,"d":"-0.03"}]
[null,9953,"BRCC3","ENSG00000185515","X",{"v":154299696,"d":"154,299,696"},{"v":154351349,"d":"154,351,349"},{"v":154984622,"d":"154,984,622"},{"v":2.08027E-5,"d":"2.08E-05"},{"v":0.00723018,"d":"7.23E-03"},{"v":0.00510986892532296,"d":"5.11E-03"},{"v":-0.0361922,"d":"-0.04"}]
[null,9954,"VBP1","ENSG00000155959","X",{"v":154425285,"d":"154,425,285"},{"v":154468098,"d":"154,468,098"},{"v":154803415,"d":"154,803,415"},{"v":8.86108e-06,"d":"8.86E-06"},{"v":0.00568637,"d":"5.69E-03"},{"v":0.00411282952418712,"d":"4.11E-03"},{"v":0.031692,"d":"0.03"}]
[null,9955,"RAB39B","ENSG00000155961","X",{"v":154487527,"d":"154,487,527"},{"v":154493874,"d":"154,493,874"},{"v":154950112,"d":"154,950,112"},{"v":2.29173e-05,"d":"2.29E-05"},{"v":0.0120196,"d":"1.20E-02"},{"v":0.00811939137648394,"d":"8.12E-03"},{"v":-0.0273579,"d":"-0.03"}]
[null,9956,"F8A2","ENSG00000198444","X",{"v":154611750,"d":"154,611,750"},{"v":154613449,"d":"154,613,449"},{"v":154428021,"d":"154,428,021"},{"v":1.37125E-17,"d":"1.37E-17"},{"v":1.75803e-16,"d":"1.76E-16"},{"v":5.10474459732761e-16,"d":"5.10E-16"},{"v":1.70906,"d":"1.71"}]
[null,9957,"F8A3","ENSG00000185990","X",{"v":154686577,"d":"154,686,577"},{"v":154688276,"d":"154,688,276"},{"v":154053666,"d":"154,053,666"},{"v":5.65672e-16,"d":"5.66E-16"},{"v":2.19168e-16,"d":"2.19E-16"},{"v":6.31395337559522e-16,"d":"6.31E-16"},{"v":1.54266,"d":"1.54"}]
[null,9958,"TMLHE","ENSG00000185973","X",{"v":154719777,"d":"154,719,777"},{"v":154899605,"d":"154,899,605"},{"v":154946000,"d":"154,946,000"},{"v":7.96895e-20,"d":"7.97E-20"},{"v":1.84107e-14,"d":"1.84E-14"},{"v":4.57736509276503E-14,"d":"4.58E-14"},{"v":0.113375,"d":"0.11"}]
[null,9959,"SPRY3","ENSG00000168939","X",{"v":154997475,"d":"154,997,475"},{"v":155012121,"d":"155,012,121"},{"v":154893692,"d":"154,893,692"},{"v":9.75787e-05,"d":"9.76E-05"},{"v":0.0457745,"d":"4.58E-02"},{"v":0.0265528176423456,"d":"2.66E-02"},{"v":0.145173,"d":"0.15"}]
[null,9960,"VAMP7","ENSG00000124333","X",{"v":155110957,"d":"155,110,957"},{"v":155173433,"d":"155,173,433"},{"v":154893692,"d":"154,893,692"},{"v":7.46119e-09,"d":"7.46E-09"},{"v":0.0666561,"d":"6.67E-02"},{"v":0.0365133393165919,"d":"3.65E-02"},{"v":0.158291,"d":"0.16"}]

{"sheet":"Table S5B","index":6,"n_rows":274,"n_cols":11,"rows_kept":274,"merged":[[0,1,0,10],[1,1,1,10]]}
[null,"Table S5B. Significent trans-acting eQTLs identified in frontal cortex tissue from 416 individuals"]
[null,"A total of 272 trans-eQTLs, regulating expression of 260 genes, were identified at the genome-wide FDR of 5%. "]
[null,"Index","Gene symbol","Ensembl ID","Gene chr.","Gene start","Gene end","eQTL Chr.","eQTL pos.","Nominal p","q value"]
[null,1,"UHMK1","ENSG00000152332",1,{"v":162467041,"d":"162,467,041"},{"v":162499419,"d":"162,499,419"},1,{"v":174996185,"d":"174,996,185"},{"v":3.75725e-15,"d":"3.76E-15"},{"v":1.2539284918887999E-5,"d":"1.25E-05"}]
[null,2,"RP11-482H16.1","ENSG00000271894",2,{"v":56374765,"d":"56,374,765"},{"v":56613306,"d":"56,613,306"},1,{"v":7542239,"d":"7,542,239"},{"v":4.68624e-14,"d":"4.69E-14"},{"v":1.5639656280069119E-4,"d":"1.56E-04"}]
[null,3,"LINC01238","ENSG00000237940",2,{"v":242912834,"d":"242,912,834"},{"v":242919427,"d":"242,919,427"},1,{"v":101498167,"d":"101,498,167"},{"v":4.40394E-17,"d":"4.40E-17"},{"v":1.469752037412672E-7,"d":"1.47E-07"}]
[null,4,"GATSL1","ENSG00000183086",7,{"v":74379083,"d":"74,379,083"},{"v":74438803,"d":"74,438,803"},1,{"v":9689452,"d":"9,689,452"},{"v":6.36649e-18,"d":"6.37E-18"},{"v":2.1247250527181119E-8,"d":"2.12E-08"}]
[null,5,"ENTPD4","ENSG00000197217",8,{"v":23243296,"d":"23,243,296"},{"v":23315208,"d":"23,315,208"},1,{"v":102734053,"d":"102,734,053"},{"v":2.76852E-14,"d":"2.77E-14"},{"v":9.23953984526976e-05,"d":"9.24E-05"}]
[null,6,"ERCC6-PGBD3","ENSG00000258838",10,{"v":50723247,"d":"50,723,247"},{"v":50747584,"d":"50,747,584"},1,{"v":38083218,"d":"38,083,218"},{"v":2.69862e-13,"d":"2.70E-13"},{"v":9.0062585848185608E-4,"d":"9.01E-04"}]
[null,7,"BMS1P4","ENSG00000271816",10,{"v":75458909,"d":"75,458,909"},{"v":75490245,"d":"75,490,245"},1,{"v":89711034,"d":"89,711,034"},{"v":1.92343e-15,"d":"1.92E-15"},{"v":6.4191727437718412E-6,"d":"6.42E-06"}]
[null,8,"RP11-96C23.5","ENSG00000271880",10,{"v":88730498,"d":"88,730,498"},{"v":88769883,"d":"88,769,883"},1,{"v":91954408,"d":"91,954,408"},{"v":9.7844e-20,"d":"9.78E-20"},{"v":3.26540366918272e-10,"d":"3.27E-10"}]
[null,9,"DNAAF4-CCPG1","ENSG00000261771",15,{"v":55647446,"d":"55,647,446"},{"v":55790558,"d":"55,790,558"},1,{"v":15511529,"d":"15,511,529"},{"v":1.38956e-13,"d":"1.39E-13"},{"v":4.6374579152012809E-4,"d":"4.64E-04"}]
[null,10,"CSPG4P8","ENSG00000188384",15,{"v":82751614,"d":"82,751,614"},{"v":82769399,"d":"82,769,399"},1,{"v":225514704,"d":"225,514,704"},{"v":1.57184e-17,"d":"1.57E-17"},{"v":5.2457913652019209E-8,"d":"5.25E-08"}]
[null,11,"CTD-3199J23.4","ENSG00000267267",17,{"v":41181274,"d":"41,181,274"},{"v":41184051,"d":"41,184,051"},1,{"v":100398079,"d":"100,398,079"},{"v":1.48317E-13,"d":"1.48E-13"},{"v":0.000494986791220896,"d":"4.95E-04"}]
[null,12,"BCKDHA","ENSG00000248098",19,{"v":41884215,"d":"41,884,215"},{"v":41930910,"d":"41,930,910"},1,{"v":34133556,"d":"34,133,556"},{"v":2.38155e-13,"d":"2.38E-13"},{"v":7.9480827729264017E-4,"d":"7.95E-04"}]
[null,13,"CTC-344H19.4","ENSG00000268401",19,{"v":46530912,"d":"46,530,912"},{"v":46533419,"d":"46,533,419"},1,{"v":68630761,"d":"68,630,761"},{"v":1.72724e-13,"d":"1.73E-13"},{"v":0.000576441665667712,"d":"5.76E-04"}]
[null,14,"ADORA2A","ENSG00000128271",22,{"v":24813847,"d":"24,813,847"},{"v":24838328,"d":"24,838,328"},1,{"v":241373744,"d":"241,373,744"},{"v":2.65923e-13,"d":"2.66E-13"},{"v":8.874800089122241E-4,"d":"8.87E-04"}]
[null,15,"SLC25A43","ENSG00000077713","X",{"v":118533023,"d":"118,533,023"},{"v":118588441,"d":"118,588,441"},1,{"v":12860180,"d":"12,860,180"},{"v":8.21639e-26,"d":"8.22E-26"},{"v":2.7421027404272323E-16,"d":"2.74E-16"}]
[null,16,"RP13-192B19.2","ENSG00000260585","X",{"v":121005722,"d":"121,005,722"},{"v":121010718,"d":"121,010,718"},1,{"v":167667363,"d":"167,667,363"},{"v":1.40677E-25,"d":"1.41E-25"},{"v":4.69489383068576e-16,"d":"4.69E-16"}]
[null,17,"SERTAD2","ENSG00000179833",2,{"v":64858755,"d":"64,858,755"},{"v":64978139,"d":"64,978,139"},2,{"v":16419276,"d":"16,419,276"},{"v":2.62463e-13,"d":"2.62E-13"},{"v":0.000875932753387744,"d":"8.76E-04"}]
[null,18,"RGPD6","ENSG00000183054",2,{"v":111271389,"d":"111,271,389"},{"v":111334762,"d":"111,334,762"},2,{"v":216388875,"d":"216,388,875"},{"v":3.4821e-15,"d":"3.48E-15"},{"v":1.16210111161248E-5,"d":"1.16E-05"}]
[null,19,"STAT1","ENSG00000115415",2,{"v":191829084,"d":"191,829,084"},{"v":191885686,"d":"191,885,686"},2,{"v":238795819,"d":"238,795,819"},{"v":9.6896E-17,"d":"9.69E-17"},{"v":3.23376552398848e-07,"d":"3.23E-07"}]
[null,20,"PCDHA9","ENSG00000204961",5,{"v":140227048,"d":"140,227,048"},{"v":140391929,"d":"140,391,929"},2,{"v":23745165,"d":"23,745,165"},{"v":3.08521e-20,"d":"3.09E-20"},{"v":1.0296447461468479E-10,"d":"1.03E-10"}]
[null,21,"NEUROD6","ENSG00000164600",7,{"v":31377075,"d":"31,377,075"},{"v":31380508,"d":"31,380,508"},2,{"v":161611179,"d":"161,611,179"},{"v":2.26693e-14,"d":"2.27E-14"},{"v":7.5655549034998407E-5,"d":"7.57E-05"}]
[null,22,"RP11-187C18.2","ENSG00000232116",9,{"v":45484572,"d":"45,484,572"},{"v":45488153,"d":"45,488,153"},2,{"v":119925177,"d":"119,925,177"},{"v":2.15222e-14,"d":"2.15E-14"},{"v":7.1827266719353609E-5,"d":"7.18E-05"}]
[null,23,"FFAR4","ENSG00000186188",10,{"v":95326422,"d":"95,326,422"},{"v":95364237,"d":"95,364,237"},2,{"v":195255111,"d":"195,255,111"},{"v":5.87233E-14,"d":"5.87E-14"},{"v":1.959806214857504E-4,"d":"1.96E-04"}]
[null,24,"MRC1L1","ENSG00000183748",10,{"v":17851362,"d":"17,851,362"},{"v":17953178,"d":"17,953,178"},2,{"v":208838690,"d":"208,838,690"},{"v":7.55041E-14,"d":"7.55E-14"},{"v":2.519841433080608E-4,"d":"2.52E-04"}]
[null,25,"PRDX3","ENSG00000165672",10,{"v":120927215,"d":"120,927,215"},{"v":120938345,"d":"120,938,345"},2,{"v":217423152,"d":"217,423,152"},{"v":8.1256E-14,"d":"8.13E-14"},{"v":0.000271180287542528,"d":"2.71E-04"}]
[null,26,"RP11-611O2.3","ENSG00000256664",12,{"v":69235726,"d":"69,235,726"},{"v":69236164,"d":"69,236,164"},2,{"v":104834838,"d":"104,834,838"},{"v":2.43248e-14,"d":"2.43E-14"},{"v":8.11805436941824E-5,"d":"8.12E-05"}]
[null,27,"TEAD4","ENSG00000197905",12,{"v":3068496,"d":"3,068,496"},{"v":3149839,"d":"3,149,839"},2,{"v":139992463,"d":"139,992,463"},{"v":1.64578E-13,"d":"1.65E-13"},{"v":0.000549255554828864,"d":"5.49E-04"}]
[null,28,"RN7SL1","ENSG00000258486",14,{"v":50053297,"d":"50,053,297"},{"v":50053596,"d":"50,053,596"},2,{"v":228993123,"d":"228,993,123"},{"v":2.53971E-13,"d":"2.54E-13"},{"v":0.000847591916996448,"d":"8.48E-04"}]
[null,29,"DPH6-DT","ENSG00000248079",15,{"v":35838396,"d":"35,838,396"},{"v":36151202,"d":"36,151,202"},2,{"v":78102127,"d":"78,102,127"},{"v":1.9436e-13,"d":"1.94E-13"},{"v":0.00064864872362368,"d":"6.49E-04"}]
[null,30,"SLC12A1","ENSG00000074803",15,{"v":48483861,"d":"48,483,861"},{"v":48596275,"d":"48,596,275"},2,{"v":215902200,"d":"215,902,200"},{"v":2.70132e-13,"d":"2.70E-13"},{"v":9.01526944895616E-4,"d":"9.02E-04"}]
[null,31,"GOLGA8B","ENSG00000215252",15,{"v":34817408,"d":"34,817,408"},{"v":34880704,"d":"34,880,704"},2,{"v":221316598,"d":"221,316,598"},{"v":5.00003e-16,"d":"5.00E-16"},{"v":1.6686885560712641E-6,"d":"1.67E-06"}]
[null,32,"AC174470.1","ENSG00000215621",17,{"v":79780293,"d":"79,780,293"},{"v":79784533,"d":"79,784,533"},2,{"v":51659679,"d":"51,659,679"},{"v":1.18441E-14,"d":"1.18E-14"},{"v":3.9527991085980804E-5,"d":"3.95E-05"}]
[null,33,"LRRC37A4P","ENSG00000214425",17,{"v":43578685,"d":"43,578,685"},{"v":43627701,"d":"43,627,701"},2,{"v":120255582,"d":"120,255,582"},{"v":4.74409e-15,"d":"4.74E-15"},{"v":1.5832722387609919E-5,"d":"1.58E-05"}]
[null,34,"ZRANB2","ENSG00000132485",1,{"v":71528974,"d":"71,528,974"},{"v":71546980,"d":"71,546,980"},3,{"v":52836337,"d":"52,836,337"},{"v":1.37186e-13,"d":"1.37E-13"},{"v":4.5783866947436805E-4,"d":"4.58E-04"}]
[null,35,"RP11-190A12.8","ENSG00000272668",1,{"v":159836744,"d":"159,836,744"},{"v":159837475,"d":"159,837,475"},3,{"v":132960656,"d":"132,960,656"},{"v":2.54549E-14,"d":"2.55E-14"},{"v":8.49520909393312e-05,"d":"8.50E-05"}]
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[null,244,"FOXD4L2","ENSG00000204828",9,{"v":42717234,"d":"42,717,234"},{"v":42720342,"d":"42,720,342"},"X",{"v":104428782,"d":"104,428,782"},{"v":6.29941e-23,"d":"6.30E-23"},{"v":2.1023380613718078E-13,"d":"2.10E-13"}]
[null,245,"ZWINT","ENSG00000122952",10,{"v":58116989,"d":"58,116,989"},{"v":58121036,"d":"58,121,036"},"X",{"v":92706401,"d":"92,706,401"},{"v":2.21023e-14,"d":"2.21E-14"},{"v":7.37632675661024e-05,"d":"7.38E-05"}]
[null,246,"SLC22A9","ENSG00000149742",11,{"v":63137261,"d":"63,137,261"},{"v":63177766,"d":"63,177,766"},"X",{"v":47449503,"d":"47,449,503"},{"v":2.73414e-19,"d":"2.73E-19"},{"v":9.124801508584319e-10,"d":"9.12E-10"}]
[null,247,"RP11-958J22.1","ENSG00000254746",11,{"v":45511239,"d":"45,511,239"},{"v":45564024,"d":"45,564,024"},"X",{"v":68471172,"d":"68,471,172"},{"v":5.34895e-17,"d":"5.35E-17"},{"v":1.78513561958576e-07,"d":"1.79E-07"}]
[null,248,"SPTY2D1","ENSG00000179119",11,{"v":18627948,"d":"18,627,948"},{"v":18656338,"d":"18,656,338"},"X",{"v":104407614,"d":"104,407,614"},{"v":2.76936e-17,"d":"2.77E-17"},{"v":9.2423432252236788E-8,"d":"9.24E-08"}]
[null,249,"PHC1P1","ENSG00000179899",12,{"v":55804263,"d":"55,804,263"},{"v":55808633,"d":"55,808,633"},"X",{"v":8808132,"d":"8,808,132"},{"v":1.26833E-14,"d":"1.27E-14"},{"v":4.23287011542304e-05,"d":"4.23E-05"}]
[null,250,"FBXL14","ENSG00000171823",12,{"v":1675159,"d":"1,675,159"},{"v":1703331,"d":"1,703,331"},"X",{"v":47828216,"d":"47,828,216"},{"v":2.70836e-14,"d":"2.71E-14"},{"v":9.03876444285568e-05,"d":"9.04E-05"}]
[null,251,"LINC00507","ENSG00000256193",12,{"v":128399917,"d":"128,399,917"},{"v":128436097,"d":"128,436,097"},"X",{"v":105427787,"d":"105,427,787"},{"v":2.05071e-18,"d":"2.05E-18"},{"v":6.84395155393248e-09,"d":"6.84E-09"}]
[null,252,"PPM1H","ENSG00000111110",12,{"v":63037762,"d":"63,037,762"},{"v":63328817,"d":"63,328,817"},"X",{"v":132990275,"d":"132,990,275"},{"v":7.62552e-14,"d":"7.63E-14"},{"v":2.5449083221685761E-4,"d":"2.54E-04"}]
[null,253,"KIF21A","ENSG00000139116",12,{"v":39687030,"d":"39,687,030"},{"v":39837192,"d":"39,837,192"},"X",{"v":146403238,"d":"146,403,238"},{"v":9.58585e-17,"d":"9.59E-17"},{"v":3.19914044420048E-7,"d":"3.20E-07"}]
[null,254,"GMPR2","ENSG00000100938",14,{"v":24701628,"d":"24,701,628"},{"v":24708448,"d":"24,708,448"},"X",{"v":130378797,"d":"130,378,797"},{"v":1.52204e-13,"d":"1.52E-13"},{"v":0.000507959098221952,"d":"5.08E-04"}]
[null,255,"ARHGAP11B","ENSG00000187951",15,{"v":30916697,"d":"30,916,697"},{"v":31065196,"d":"31,065,196"},"X",{"v":25260473,"d":"25,260,473"},{"v":1.03398e-27,"d":"1.03E-27"},{"v":3.4507604818502398E-18,"d":"3.45E-18"}]
[null,256,"CKMT1B","ENSG00000237289",15,{"v":43885252,"d":"43,885,252"},{"v":43897099,"d":"43,897,099"},"X",{"v":31944486,"d":"31,944,486"},{"v":4.99225e-15,"d":"4.99E-15"},{"v":1.6660920922568e-05,"d":"1.67E-05"}]
[null,257,"MAGEL2","ENSG00000254585",15,{"v":23888691,"d":"23,888,691"},{"v":23891175,"d":"23,891,175"},"X",{"v":32347915,"d":"32,347,915"},{"v":1.21148e-15,"d":"1.21E-15"},{"v":4.04314136497024e-06,"d":"4.04E-06"}]
[null,258,"AC011330.5","ENSG00000249839",15,{"v":43955852,"d":"43,955,852"},{"v":43976537,"d":"43,976,537"},"X",{"v":149821077,"d":"149,821,077"},{"v":7.20374e-14,"d":"7.20E-14"},{"v":2.4041452749109119E-4,"d":"2.40E-04"}]
[null,259,"PDXDC1","ENSG00000179889",16,{"v":15068448,"d":"15,068,448"},{"v":15233196,"d":"15,233,196"},"X",{"v":115921324,"d":"115,921,324"},{"v":2.9021e-13,"d":"2.90E-13"},{"v":0.00096853440050848,"d":"9.69E-04"}]
[null,260,"RP11-645C24.5","ENSG00000260306",16,{"v":21805416,"d":"21,805,416"},{"v":21807080,"d":"21,807,080"},"X",{"v":118852950,"d":"118,852,950"},{"v":9.06006e-14,"d":"9.06E-14"},{"v":3.0236655458705286E-4,"d":"3.02E-04"}]
[null,261,"GRIN2A","ENSG00000183454",16,{"v":9852376,"d":"9,852,376"},{"v":10276611,"d":"10,276,611"},"X",{"v":120195087,"d":"120,195,087"},{"v":8.14837E-14,"d":"8.15E-14"},{"v":2.719402037514656E-4,"d":"2.72E-04"}]
[null,262,"AC007347.1","ENSG00000214696",16,{"v":54146970,"d":"54,146,970"},{"v":54148378,"d":"54,148,378"},"X",{"v":145545951,"d":"145,545,951"},{"v":3.03887e-16,"d":"3.04E-16"},{"v":1.0141794334010561E-6,"d":"1.01E-06"}]
[null,263,"MPO","ENSG00000005381",17,{"v":56347217,"d":"56,347,217"},{"v":56358296,"d":"56,358,296"},"X",{"v":16696840,"d":"16,696,840"},{"v":7.37786e-19,"d":"7.38E-19"},{"v":2.4622553365271683E-9,"d":"2.46E-09"}]
[null,264,"TBC1D3","ENSG00000197681",17,{"v":36337711,"d":"36,337,711"},{"v":36358166,"d":"36,358,166"},"X",{"v":29605016,"d":"29,605,016"},{"v":1.12403E-19,"d":"1.12E-19"},{"v":3.75128948762464e-10,"d":"3.75E-10"}]
[null,265,"NOG","ENSG00000183691",17,{"v":54671060,"d":"54,671,060"},{"v":54672951,"d":"54,672,951"},"X",{"v":68980960,"d":"68,980,960"},{"v":4.17336E-18,"d":"4.17E-18"},{"v":1.3927992576775682E-8,"d":"1.39E-08"}]
[null,266,"CCDC47","ENSG00000108588",17,{"v":61822610,"d":"61,822,610"},{"v":61853711,"d":"61,853,711"},"X",{"v":82277000,"d":"82,277,000"},{"v":1.06263E-16,"d":"1.06E-16"},{"v":3.54637576242144e-07,"d":"3.55E-07"}]
[null,267,"YPEL2","ENSG00000175155",17,{"v":57409050,"d":"57,409,050"},{"v":57479090,"d":"57,479,090"},"X",{"v":89615462,"d":"89,615,462"},{"v":1.94774E-13,"d":"1.95E-13"},{"v":0.000650030389458112,"d":"6.50E-04"}]
[null,268,"EIF4A3","ENSG00000141543",17,{"v":78109013,"d":"78,109,013"},{"v":78120982,"d":"78,120,982"},"X",{"v":149740193,"d":"149,740,193"},{"v":2.34013e-17,"d":"2.34E-17"},{"v":7.80984944234144E-8,"d":"7.81E-08"}]
[null,269,"PPFIA3","ENSG00000177380",19,{"v":49622646,"d":"49,622,646"},{"v":49654283,"d":"49,654,283"},"X",{"v":36140540,"d":"36,140,540"},{"v":2.51568e-13,"d":"2.52E-13"},{"v":8.3957224791398406E-4,"d":"8.40E-04"}]
[null,270,"ZHX3","ENSG00000174306",20,{"v":39807088,"d":"39,807,088"},{"v":39946312,"d":"39,946,312"},"X",{"v":42579492,"d":"42,579,492"},{"v":3.29334e-18,"d":"3.29E-18"},{"v":1.099105159219392E-8,"d":"1.10E-08"}]
[null,271,"CTA-390C10.10","ENSG00000272977",22,{"v":25872185,"d":"25,872,185"},{"v":25875938,"d":"25,875,938"},"X",{"v":91999245,"d":"91,999,245"},{"v":2.50233e-17,"d":"2.50E-17"},{"v":8.35116876201504e-08,"d":"8.35E-08"}]

{"sheet":"Table S6","index":7,"n_rows":469,"n_cols":20,"rows_kept":469,"merged":[[0,1,0,17],[1,1,1,19],[2,1,3,1],[2,2,2,8],[2,9,2,13],[2,14,2,19]]}
[null,"Table S6. Co-localized analysis for pQTL and eQTL"]
[null,"To investigate whether the association signals for gene and protein expression levels are driven by the same genetic variant, we performed a colocalization analysis using the COLOC software  for 9,495 genes with significant cis-eQTL and 883 proteins with cis-pQTL. The colocalization analysis estimates five posterior probabilities (PP0, PP1, PP2, PP3, and PP4) for five hypotheses (see methods). We identified 487 genomic loci harboring both significant cis-pQTLs and cis-eQTLs within 1 Mb region."]
[null,"Index","pQTL",{"$nulls":6},"eQTL",{"$nulls":4},"Colocalization"]
[null,null,"Gene symbol","Protein accession","Chr","cis-pQTL position","Effect size","cis-pQTL p value","cis-pQTL q value","Ensembl ID","cis-eQTL position","Effect size","cis-eQTL p value","cis-eQTL q value","# of SNPs tested","PP0","PP1","PP2","PP3","PP4"]
[null,1,"SLC2A5","P22732",1,{"v":9092343,"d":"9,092,343"},{"v":-0.133652,"d":"-0.13"},{"v":1.73847e-07,"d":"1.74E-07"},{"v":0.0180289810133511,"d":"1.80E-02"},"ENSG00000142583",{"v":9120552,"d":"9,120,552"},{"v":-0.165429,"d":"-0.17"},{"v":2.56804E-11,"d":"2.57E-11"},{"v":2.04222538363882E-7,"d":"2.04E-07"},83,{"v":3.16960420138812e-06,"d":"0.00"},{"v":1.00418676641417e-05,"d":"0.00"},{"v":2.58080405003531E-3,"d":"0.00"},{"v":0.00718622470802363,"d":"0.01"},{"v":0.990219759770076,"d":"0.99"}]
[null,2,"PIK3CD","O00329",1,{"v":9743729,"d":"9,743,729"},{"v":0.0549415,"d":"0.05"},{"v":1.41433e-07,"d":"1.41E-07"},{"v":0.0206285043060433,"d":"2.06E-02"},"ENSG00000171608",{"v":9750457,"d":"9,750,457"},{"v":0.127222,"d":"0.13"},{"v":3.54463E-32,"d":"3.54E-32"},{"v":6.08359656284848e-24,"d":"6.08E-24"},114,{"v":2.12267461241343e-22,"d":"0.00"},{"v":2.48906077469226e-21,"d":"0.00"},{"v":0.00105328070306797,"d":"0.00"},{"v":0.0113632481986034,"d":"0.01"},{"v":0.987583471098328,"d":"0.99"}]
[null,3,"AGMAT","Q9BSE5",1,{"v":15940680,"d":"15,940,680"},{"v":-0.181031,"d":"-0.18"},{"v":3.9211E-10,"d":"3.92E-10"},{"v":5.24144962404551e-05,"d":"5.24E-05"},"ENSG00000116771",{"v":15835234,"d":"15,835,234"},{"v":0.242855,"d":"0.24"},{"v":4.19663e-36,"d":"4.20E-36"},{"v":1.8229632996759E-29,"d":"1.82E-29"},540,{"v":9.0529510582788e-09,"d":"0.00"},{"v":2.1413486298294e-05,"d":"0.00"},{"v":7.19358592701965e-05,"d":"0.00"},{"v":0.169323605020106,"d":"0.17"},{"v":0.830583036581375,"d":"0.83"}]
[null,4,"ALDH4A1","P30038",1,{"v":19220907,"d":"19,220,907"},{"v":0.34631,"d":"0.35"},{"v":4.2049e-12,"d":"4.20E-12"},{"v":1.37973354394988E-6,"d":"1.38E-06"},"ENSG00000159423",{"v":19221621,"d":"19,221,621"},{"v":0.389978,"d":"0.39"},{"v":4.03808e-20,"d":"4.04E-20"},{"v":3.37085685817727e-14,"d":"3.37E-14"},61,{"v":0.00247342721011618,"d":"0.00"},{"v":1.38131214368391E-3,"d":"0.00"},{"v":0.0499535638947674,"d":"0.05"},{"v":0.0269778935569576,"d":"0.03"},{"v":0.919213803194475,"d":"0.92"}]
[null,5,"HMGCL","P35914",1,{"v":24129126,"d":"24,129,126"},{"v":0.0771398,"d":"0.08"},{"v":2.97556e-12,"d":"2.98E-12"},{"v":2.16580059344119e-06,"d":"2.17E-06"},"ENSG00000117305",{"v":24165248,"d":"24,165,248"},{"v":0.0926823,"d":"0.09"},{"v":6.13248e-22,"d":"6.13E-22"},{"v":3.92564005259391e-19,"d":"3.93E-19"},253,{"v":1.78144024065474e-17,"d":"0.00"},{"v":3.39620114846746e-13,"d":"0.00"},{"v":2.01939112250154E-5,"d":"0.00"},{"v":0.384368307295141,"d":"0.38"},{"v":0.615611498793295,"d":"0.62"}]
[null,6,"RPA2","P15927-3",1,{"v":28241083,"d":"28,241,083"},{"v":0.22909,"d":"0.23"},{"v":1.24328e-16,"d":"1.24E-16"},{"v":2.91130663851596e-09,"d":"2.91E-09"},"ENSG00000117748",{"v":28241083,"d":"28,241,083"},{"v":0.462333,"d":"0.46"},{"v":2.05699e-98,"d":"2.06E-98"},{"v":5.47844079981294e-74,"d":"5.48E-74"},166,{"v":1.39567730118697e-41,"d":"0.00"},{"v":2.98240234342321e-39,"d":"0.00"},{"v":1.13877084848691e-05,"d":"0.00"},{"v":1.43486897141562E-3,"d":"0.00"},{"v":0.998553743320099,"d":"1.00"}]
[null,7,"RPA2","P15927",1,{"v":28241083,"d":"28,241,083"},{"v":0.228508,"d":"0.23"},{"v":3.21556e-16,"d":"3.22E-16"},{"v":3.19420133821324E-9,"d":"3.19E-09"},"ENSG00000117748",{"v":28241083,"d":"28,241,083"},{"v":0.462333,"d":"0.46"},{"v":2.05699e-98,"d":"2.06E-98"},{"v":5.47844079981294e-74,"d":"5.48E-74"},165,{"v":2.3989312362239E-41,"d":"0.00"},{"v":3.25331429250249E-39,"d":"0.00"},{"v":1.95735286159138e-05,"d":"0.00"},{"v":1.65614281566369E-3,"d":"0.00"},{"v":0.99832428365572,"d":"1.00"}]
[null,8,"NT5C1A","Q9BXI3",1,{"v":40149875,"d":"40,149,875"},{"v":0.0861086,"d":"0.09"},{"v":3.73302e-07,"d":"3.73E-07"},{"v":0.017425384377151,"d":"1.74E-02"},"ENSG00000116981",{"v":40144090,"d":"40,144,090"},{"v":0.130682,"d":"0.13"},{"v":2.4499e-11,"d":"2.45E-11"},{"v":3.9599314602363e-07,"d":"3.96E-07"},66,{"v":1.28232356812131e-06,"d":"0.00"},{"v":2.35503496281917e-06,"d":"0.00"},{"v":0.00390261413476213,"d":"0.00"},{"v":0.00617737975075792,"d":"0.01"},{"v":0.98991636875595,"d":"0.99"}]
[null,9,"HYI","Q5T013",1,{"v":43919081,"d":"43,919,081"},{"v":-0.403602,"d":"-0.40"},{"v":1.75882E-13,"d":"1.76E-13"},{"v":4.4199900226836e-06,"d":"4.42E-06"},"ENSG00000178922",{"v":43916642,"d":"43,916,642"},{"v":0.168084,"d":"0.17"},{"v":2.49453e-39,"d":"2.49E-39"},{"v":5.33315314613188e-33,"d":"5.33E-33"},150,{"v":1.12077396025533e-27,"d":"0.00"},{"v":6.49427546406458e-26,"d":"0.00"},{"v":0.00030210537099337,"d":"0.00"},{"v":0.0165221872648218,"d":"0.02"},{"v":0.983175707364187,"d":"0.98"}]
[null,10,"FAAH","O00519",1,{"v":46797692,"d":"46,797,692"},{"v":-0.142975,"d":"-0.14"},{"v":3.15881e-19,"d":"3.16E-19"},{"v":6.83650336702985e-13,"d":"6.84E-13"},"ENSG00000117480",{"v":46898338,"d":"46,898,338"},{"v":-0.0632433,"d":"-0.06"},{"v":2.23368e-11,"d":"2.23E-11"},{"v":3.77103612710035e-07,"d":"3.77E-07"},87,{"v":1.54250508111068e-09,"d":"0.00"},{"v":0.00052144705323381,"d":"0.00"},{"v":5.22853126894786E-8,"d":"0.00"},{"v":0.0166923726546695,"d":"0.02"},{"v":0.982786126464278,"d":"0.98"}]
[null,11,"COA7","Q96BR5",1,{"v":53144641,"d":"53,144,641"},{"v":-0.108158,"d":"-0.11"},{"v":2.77753e-13,"d":"2.78E-13"},{"v":5.71764185710821e-08,"d":"5.72E-08"},"ENSG00000162377",{"v":53129119,"d":"53,129,119"},{"v":-0.073619,"d":"-0.07"},{"v":1.66376e-14,"d":"1.66E-14"},{"v":1.46105887495892E-6,"d":"1.46E-06"},298,{"v":5.88446121443812e-13,"d":"0.00"},{"v":1.17190694841928e-07,"d":"0.00"},{"v":2.92953965602122e-07,"d":"0.00"},{"v":0.0574000039839771,"d":"0.06"},{"v":0.942599585870774,"d":"0.94"}]
[null,12,"C1orf123","Q9NWV4",1,{"v":53693090,"d":"53,693,090"},{"v":-0.0967149,"d":"-0.10"},{"v":1.60828e-10,"d":"1.61E-10"},{"v":0.00252941395210556,"d":"2.53E-03"},"ENSG00000162384",{"v":53701581,"d":"53,701,581"},{"v":-0.0801993,"d":"-0.08"},{"v":1.01378E-21,"d":"1.01E-21"},{"v":5.38566429754599e-18,"d":"5.39E-18"},100,{"v":1.43740834331876E-15,"d":"0.00"},{"v":1.30971441243762E-12,"d":"0.00"},{"v":3.62002596516168e-05,"d":"0.00"},{"v":0.0320164178613626,"d":"0.03"},{"v":0.967947381877677,"d":"0.97"}]
[null,13,"ACOT11","Q8WXI4",1,{"v":55074840,"d":"55,074,840"},{"v":0.177364,"d":"0.18"},{"v":6.54003e-18,"d":"6.54E-18"},{"v":1.30301397683131e-11,"d":"1.30E-11"},"ENSG00000162390",{"v":55046392,"d":"55,046,392"},{"v":-0.114707,"d":"-0.11"},{"v":2.22237E-19,"d":"2.22E-19"},{"v":1.64120092590738e-15,"d":"1.64E-15"},117,{"v":5.57728129351282E-20,"d":"0.00"},{"v":1.86598310942626E-11,"d":"0.00"},{"v":1.23781546743732e-10,"d":"0.00"},{"v":0.0404538707898741,"d":"0.04"},{"v":0.959546129067686,"d":"0.96"}]
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[null,448,"GNB1L","Q9BYB4",22,{"v":19840196,"d":"19,840,196"},{"v":0.12588,"d":"0.13"},{"v":1.03224e-12,"d":"1.03E-12"},{"v":1.22190193640885E-6,"d":"1.22E-06"},"ENSG00000185838",{"v":19840196,"d":"19,840,196"},{"v":0.111411,"d":"0.11"},{"v":4.42541e-08,"d":"4.43E-08"},{"v":2.61433370784902e-05,"d":"2.61E-05"},37,{"v":6.52667733752175e-07,"d":"0.00"},{"v":0.00081512961861014,"d":"0.00"},{"v":3.28384273953061e-06,"d":"0.00"},{"v":3.10518027826394E-3,"d":"0.00"},{"v":0.996075753592652,"d":"1.00"}]
[null,449,"TANGO2","F8WDT9",22,{"v":20006354,"d":"20,006,354"},{"v":0.0788692,"d":"0.08"},{"v":2.97787e-07,"d":"2.98E-07"},{"v":0.010963202178862,"d":"1.10E-02"},"ENSG00000183597",{"v":20005258,"d":"20,005,258"},{"v":0.0502173,"d":"0.05"},{"v":1.87733e-08,"d":"1.88E-08"},{"v":2.47444262619896e-05,"d":"2.47E-05"},68,{"v":1.8766828987347E-4,"d":"0.00"},{"v":0.00236813262499201,"d":"0.00"},{"v":1.89541706704555E-3,"d":"0.00"},{"v":0.0229451237183577,"d":"0.02"},{"v":0.972603658299732,"d":"0.97"}]
[null,450,"TANGO2","Q6ICL3",22,{"v":20009078,"d":"20,009,078"},{"v":0.068391,"d":"0.07"},{"v":4.46301e-08,"d":"4.46E-08"},{"v":2.4369180617359E-3,"d":"2.44E-03"},"ENSG00000183597",{"v":20005258,"d":"20,005,258"},{"v":0.0502173,"d":"0.05"},{"v":1.87733e-08,"d":"1.88E-08"},{"v":2.47444262619896e-05,"d":"2.47E-05"},63,{"v":6.82691196269035e-05,"d":"0.00"},{"v":3.45384722113174E-3,"d":"0.00"},{"v":0.00068797623148828,"d":"0.00"},{"v":0.0338439048464765,"d":"0.03"},{"v":0.961946002581277,"d":"0.96"}]
[null,451,"AIFM3","Q96NN9",22,{"v":21443816,"d":"21,443,816"},{"v":0.0464175,"d":"0.05"},{"v":7.33928e-06,"d":"7.34E-06"},{"v":0.0461155989921774,"d":"4.61E-02"},"ENSG00000183773",{"v":21334924,"d":"21,334,924"},{"v":-0.0701424,"d":"-0.07"},{"v":2.13494e-09,"d":"2.13E-09"},{"v":7.61334539320196E-6,"d":"7.61E-06"},18,{"v":1.10963424365952E-3,"d":"0.00"},{"v":7.07335960059212E-5,"d":"0.00"},{"v":0.137928617810808,"d":"0.14"},{"v":0.00793930320134385,"d":"0.01"},{"v":0.852951711148183,"d":"0.85"}]
[null,452,"GSTT2B","P0CG30",22,{"v":24297287,"d":"24,297,287"},{"v":0.743318,"d":"0.74"},{"v":3.46873E-53,"d":"3.47E-53"},{"v":9.8078526479557e-38,"d":"9.81E-38"},"ENSG00000133433",{"v":24292957,"d":"24,292,957"},{"v":1.20119,"d":"1.20"},{"v":1.45541E-56,"d":"1.46E-56"},{"v":2.11490486026069E-38,"d":"2.11E-38"},526,{"v":1.5453290728811e-73,"d":"0.00"},{"v":5.05429862348859e-39,"d":"0.00"},{"v":5.21508298955278e-37,"d":"0.00"},{"v":0.0160730139840604,"d":"0.02"},{"v":0.983926986015937,"d":"0.98"}]
[null,453,"NIPSNAP1","Q9BPW8",22,{"v":29985012,"d":"29,985,012"},{"v":-0.0483734,"d":"-0.05"},{"v":1.02676E-7,"d":"1.03E-07"},{"v":0.00471634866594072,"d":"4.72E-03"},"ENSG00000184117",{"v":29969861,"d":"29,969,861"},{"v":-0.057385,"d":"-0.06"},{"v":4.78379e-24,"d":"4.78E-24"},{"v":6.65587416116408e-18,"d":"6.66E-18"},416,{"v":5.58997078303954e-17,"d":"0.00"},{"v":1.9581781926112e-15,"d":"0.00"},{"v":0.00079910090721379,"d":"0.00"},{"v":0.027020487724744,"d":"0.03"},{"v":0.972180411368041,"d":"0.97"}]
[null,454,"PISD","Q9UG56",22,{"v":32036692,"d":"32,036,692"},{"v":-0.211367,"d":"-0.21"},{"v":2.63063E-8,"d":"2.63E-08"},{"v":0.0139395313789672,"d":"1.39E-02"},"ENSG00000241878",{"v":32015162,"d":"32,015,162"},{"v":0.0825057,"d":"0.08"},{"v":1.05682e-29,"d":"1.06E-29"},{"v":1.49039548143954e-24,"d":"1.49E-24"},304,{"v":5.31602381243018e-11,"d":"0.00"},{"v":2.76811248307934E-10,"d":"0.00"},{"v":0.0350021122626312,"d":"0.04"},{"v":0.181476354093619,"d":"0.18"},{"v":0.783521533313779,"d":"0.78"}]
[null,455,"SYN3","O14994",22,{"v":33435475,"d":"33,435,475"},{"v":-0.0747598,"d":"-0.07"},{"v":9.31509e-08,"d":"9.32E-08"},{"v":0.00822680683701024,"d":"8.23E-03"},"ENSG00000185666",{"v":33440219,"d":"33,440,219"},{"v":-0.098466,"d":"-0.10"},{"v":7.03605e-10,"d":"7.04E-10"},{"v":5.30916202004415e-06,"d":"5.31E-06"},162,{"v":2.4116168199093E-4,"d":"0.00"},{"v":0.00121522114592531,"d":"0.00"},{"v":0.00948769669336526,"d":"0.01"},{"v":0.0468666066471142,"d":"0.05"},{"v":0.942189313831604,"d":"0.94"}]
[null,456,"APOL2","Q9BQE5",22,{"v":36635756,"d":"36,635,756"},{"v":-0.139089,"d":"-0.14"},{"v":8.01265e-11,"d":"8.01E-11"},{"v":2.30908235367136E-5,"d":"2.31E-05"},"ENSG00000128335",{"v":36635756,"d":"36,635,756"},{"v":-0.190585,"d":"-0.19"},{"v":1.14354E-37,"d":"1.14E-37"},{"v":5.83164051551167e-29,"d":"5.83E-29"},16,{"v":8.93843001155141e-28,"d":"0.00"},{"v":2.15705666371951E-25,"d":"0.00"},{"v":4.15209682650009e-06,"d":"0.00"},{"v":2.00629896141965e-06,"d":"0.00"},{"v":0.999993841604214,"d":"1.00"}]
[null,457,"TST","Q16762",22,{"v":37411703,"d":"37,411,703"},{"v":0.135792,"d":"0.14"},{"v":4.08284e-10,"d":"4.08E-10"},{"v":0.000790130984334213,"d":"7.90E-04"},"ENSG00000128311",{"v":37420123,"d":"37,420,123"},{"v":0.20882,"d":"0.21"},{"v":3.08045e-20,"d":"3.08E-20"},{"v":2.94265035660646e-17,"d":"2.94E-17"},114,{"v":1.58728540663609E-12,"d":"0.00"},{"v":1.27532617772309E-10,"d":"0.00"},{"v":9.31030045105304e-05,"d":"0.00"},{"v":0.00648706845558265,"d":"0.01"},{"v":0.993419828410788,"d":"0.99"}]
[null,458,"TRIOBP","Q9H2D6",22,{"v":38115692,"d":"38,115,692"},{"v":-0.0466728,"d":"-0.05"},{"v":4.21525e-07,"d":"4.22E-07"},{"v":0.0195008767080374,"d":"1.95E-02"},"ENSG00000100106",{"v":38163013,"d":"38,163,013"},{"v":-0.151773,"d":"-0.15"},{"v":5.96134e-35,"d":"5.96E-35"},{"v":2.34710842034667e-32,"d":"2.35E-32"},232,{"v":5.69375682953376e-23,"d":"0.00"},{"v":6.73741794736141e-22,"d":"0.00"},{"v":0.00651887671885247,"d":"0.01"},{"v":0.0762205560223361,"d":"0.08"},{"v":0.917260567258813,"d":"0.92"}]
[null,459,"CSDC2","Q9Y534",22,{"v":41915329,"d":"41,915,329"},{"v":0.234369,"d":"0.23"},{"v":3.25355e-10,"d":"3.25E-10"},{"v":1.6633783751978e-05,"d":"1.66E-05"},"ENSG00000172346",{"v":41942904,"d":"41,942,904"},{"v":0.302809,"d":"0.30"},{"v":3.83483E-37,"d":"3.83E-37"},{"v":6.15619272268794e-32,"d":"6.16E-32"},788,{"v":9.09555573817181e-25,"d":"0.00"},{"v":1.32928025366069E-21,"d":"0.00"},{"v":5.96807182301159e-05,"d":"0.00"},{"v":0.0863074259966553,"d":"0.09"},{"v":0.913632893285115,"d":"0.91"}]
[null,460,"TTC38","Q5R3I4",22,{"v":46677003,"d":"46,677,003"},{"v":0.566718,"d":"0.57"},{"v":6.59372e-15,"d":"6.59E-15"},{"v":4.90807418418852E-9,"d":"4.91E-09"},"ENSG00000075234",{"v":46677904,"d":"46,677,904"},{"v":0.501509,"d":"0.50"},{"v":2.09796e-33,"d":"2.10E-33"},{"v":5.02283500225287e-24,"d":"5.02E-24"},197,{"v":1.87792973567726e-08,"d":"0.00"},{"v":1.62391663463259e-07,"d":"0.00"},{"v":6.07030964496759E-3,"d":"0.01"},{"v":0.0515498761876317,"d":"0.05"},{"v":0.94237963299644,"d":"0.94"}]
[null,461,"MAPK12","P53778",22,{"v":50661869,"d":"50,661,869"},{"v":0.0651405,"d":"0.07"},{"v":2.24575e-08,"d":"2.25E-08"},{"v":1.59603090944519E-3,"d":"1.60E-03"},"ENSG00000188130",{"v":50692562,"d":"50,692,562"},{"v":0.140684,"d":"0.14"},{"v":8.56801e-47,"d":"8.57E-47"},{"v":2.8086213811738E-38,"d":"2.81E-38"},177,{"v":8.34118609892621e-32,"d":"0.00"},{"v":2.15506591868893e-30,"d":"0.00"},{"v":1.21793704107717E-3,"d":"0.00"},{"v":0.0304988796062674,"d":"0.03"},{"v":0.968283183352653,"d":"0.97"}]
[null,462,"TYMP","P19971",22,{"v":50957520,"d":"50,957,520"},{"v":-0.167195,"d":"-0.17"},{"v":2.01084E-7,"d":"2.01E-07"},{"v":0.0199636094511819,"d":"2.00E-02"},"ENSG00000025708",{"v":50971047,"d":"50,971,047"},{"v":-0.257442,"d":"-0.26"},{"v":8.13342e-10,"d":"8.13E-10"},{"v":8.51753020818062e-06,"d":"8.52E-06"},91,{"v":1.98955357078002e-05,"d":"0.00"},{"v":0.00013291711875249,"d":"0.00"},{"v":0.00298948944468447,"d":"0.00"},{"v":0.0189941708712537,"d":"0.02"},{"v":0.977863527029602,"d":"0.98"}]
[null,463,"TYMP","C9JGI3",22,{"v":50957520,"d":"50,957,520"},{"v":-0.18073,"d":"-0.18"},{"v":4.83471e-08,"d":"4.83E-08"},{"v":0.0271020503493955,"d":"2.71E-02"},"ENSG00000025708",{"v":50971047,"d":"50,971,047"},{"v":-0.257442,"d":"-0.26"},{"v":8.13342e-10,"d":"8.13E-10"},{"v":8.51753020818062e-06,"d":"8.52E-06"},98,{"v":6.0689912403537E-6,"d":"0.00"},{"v":1.0651063358894E-4,"d":"0.00"},{"v":0.00091214780661808,"d":"0.00"},{"v":0.0150242185019659,"d":"0.02"},{"v":0.983951054066586,"d":"0.98"}]
[null,464,"ARSA","P15289",22,{"v":51145702,"d":"51,145,702"},{"v":-0.262053,"d":"-0.26"},{"v":6.8706E-10,"d":"6.87E-10"},{"v":0.00114673677743933,"d":"1.15E-03"},"ENSG00000100299",{"v":51087027,"d":"51,087,027"},{"v":-0.145524,"d":"-0.15"},{"v":1.28393e-10,"d":"1.28E-10"},{"v":1.87905252109207e-06,"d":"1.88E-06"},39,{"v":0.133768777115573,"d":"0.13"},{"v":0.0280971398598563,"d":"0.03"},{"v":0.114516505564466,"d":"0.11"},{"v":0.0233530784595503,"d":"0.02"},{"v":0.700264499000554,"d":"0.70"}]
[null,465,"TMLHE","Q9NVH6","X",{"v":154946000,"d":"154,946,000"},{"v":0.145029,"d":"0.15"},{"v":3.42664e-23,"d":"3.43E-23"},{"v":1.23842200335728e-18,"d":"1.24E-18"},"ENSG00000185973",{"v":154946000,"d":"154,946,000"},{"v":0.113375,"d":"0.11"},{"v":7.96895e-20,"d":"7.97E-20"},{"v":4.61469939195561e-14,"d":"4.61E-14"},63,{"v":9.19954341437828e-22,"d":"0.00"},{"v":2.086040724846E-11,"d":"0.00"},{"v":7.93495766801838e-14,"d":"0.00"},{"v":8.0008991333406E-4,"d":"0.00"},{"v":0.999199910065729,"d":"1.00"}]

{"sheet":"Table S7","index":8,"n_rows":415,"n_cols":14,"rows_kept":415,"merged":[[0,1,0,11],[1,1,1,13],[2,1,3,1],[2,2,3,2],[2,3,3,3],[2,4,2,6],[2,7,2,9],[2,10,3,10],[2,11,3,11],[2,12,3,12],[2,13,3,13]]}
[null,"Table S7. Transcript-independent and Transcript-dependent regulations identified by mediation analysis"]
[null,"A total of 262 and 411 transcript-dependent and transcript-independent regulations were identified, respectively. The mediation analysis was performed using conditional QTL mapping approach by considering the corresponding transcript as a co-variate. The significance level was determined by permuting samples for 1,000 times to produce a null distribution. Z-score was calculated from p-values of the sample with permutation and the null distribution. "]
[null,"Index","Gene symbol","Protein accession","No conditional mapping",null,null,"Conditional mapping",null,null,"Zscore","Difference between p values","Regulation","PP4"]
[{"$nulls":4},"Nominal p","Slope","Beta p","Nominal p","Slope","Beta p"]
[null,1,"FDPS","A0A087X090",{"v":8.92e-16,"d":"8.92E-16"},{"v":-0.183784,"d":"-0.18"},2.26E-10,1.12E-13,{"v":-0.171572,"d":"-0.17"},{"v":1.73e-13,"d":"1.73E-13"},{"v":-6.811516109,"d":"-6.81"},{"v":2.09885316829406,"d":"2.10"},"Transcript-dependent",{"v":0.931244705724029,"d":"0.93"}]
[null,2,"SH3PXD2B","A1X283",{"v":3.6e-17,"d":"3.60E-17"},{"v":0.0938486,"d":"0.09"},{"v":5.66e-11,"d":"5.66E-11"},{"v":1.77e-07,"d":"1.77E-07"},{"v":0.0558454,"d":"0.06"},{"v":7.09e-08,"d":"7.09E-08"},{"v":-23.70980501,"d":"-23.71"},{"v":9.69167076559452,"d":"9.69"},"Transcript-dependent",{"v":0.992914392153528,"d":"0.99"}]
[null,3,"VWA8","A3KMH1",1.32E-46,{"v":-0.216606,"d":"-0.22"},1.45E-37,{"v":5.86e-41,"d":"5.86E-41"},{"v":-0.206344,"d":"-0.21"},{"v":5.08e-42,"d":"5.08E-42"},{"v":-11.04849749,"d":"-11.05"},{"v":5.64732368481224,"d":"5.65"},"Transcript-dependent",{"v":0.9351109862489,"d":"0.94"}]
[null,4,"MBLAC1","A4D2B0",{"v":2.39e-23,"d":"2.39E-23"},{"v":-0.405006,"d":"-0.41"},{"v":8.64e-12,"d":"8.64E-12"},{"v":5.19e-19,"d":"5.19E-19"},{"v":-0.360595,"d":"-0.36"},{"v":8.03e-19,"d":"8.03E-19"},{"v":-5.730405505,"d":"-5.73"},{"v":4.33676945690032,"d":"4.34"},"Transcript-dependent",{"v":0.81643348887764,"d":"0.82"}]
[null,5,"WIPF3","A6NGB9",2.09E-10,{"v":-0.168549,"d":"-0.17"},{"v":0.000239945,"d":"2.40E-04"},{"v":2.9e-06,"d":"2.90E-06"},{"v":-0.119963,"d":"-0.12"},{"v":6.97e-06,"d":"6.97E-06"},{"v":-18.56514345,"d":"-18.57"},{"v":4.1422517117879,"d":"4.14"},"Transcript-dependent",{"v":0.914126586310661,"d":"0.91"}]
[null,6,"DISP2","A7MBM2",{"v":4.98e-09,"d":"4.98E-09"},{"v":0.084683,"d":"0.08"},{"v":2.24e-05,"d":"2.24E-05"},{"v":3.13e-06,"d":"3.13E-06"},{"v":0.0676052,"d":"0.07"},{"v":3.22E-7,"d":"3.22E-07"},{"v":-14.17355231,"d":"-14.17"},{"v":2.79831499478673,"d":"2.80"},"Transcript-dependent",{"v":0.9832991869916,"d":"0.98"}]
[null,7,"LYRM9","A8MSI8",{"v":2.06e-12,"d":"2.06E-12"},{"v":-0.224232,"d":"-0.22"},{"v":5.62e-07,"d":"5.62E-07"},{"v":0.000495082,"d":"4.95E-04"},{"v":-0.109438,"d":"-0.11"},{"v":0.000559961,"d":"5.60E-04"},{"v":-23.81594237,"d":"-23.82"},{"v":8.38080991633845,"d":"8.38"},"Transcript-dependent",{"v":0.984810670816804,"d":"0.98"}]
[null,8,"SIRPB1","O00241",{"v":8.05e-16,"d":"8.05E-16"},{"v":-0.213143,"d":"-0.21"},{"v":0.00191381,"d":"1.91E-03"},{"v":0.000775448,"d":"7.75E-04"},{"v":-0.0897712,"d":"-0.09"},{"v":1.49967E-3,"d":"1.50E-03"},{"v":-26.7679701,"d":"-26.77"},{"v":11.9837567998343,"d":"11.98"},"Transcript-dependent",{"v":0.935573412270012,"d":"0.94"}]
[null,9,"PIK3CD","O00329",{"v":1.41e-07,"d":"1.41E-07"},{"v":0.0549415,"d":"0.05"},{"v":1.69794E-3,"d":"1.70E-03"},{"v":0.0470093,"d":"4.70E-02"},{"v":0.0196322,"d":"0.02"},{"v":0.0449575,"d":"4.50E-02"},{"v":-23.19880209,"d":"-23.20"},{"v":5.52296467164496,"d":"5.52"},"Transcript-dependent",{"v":0.987583471098328,"d":"0.99"}]
[null,10,"FPGT","O14772",{"v":3.54e-12,"d":"3.54E-12"},{"v":0.0975349,"d":"0.10"},{"v":9.52e-09,"d":"9.52E-09"},{"v":0.0137958,"d":"1.38E-02"},{"v":0.0320948,"d":"0.03"},{"v":0.0119723,"d":"1.20E-02"},{"v":-26.31493325,"d":"-26.31"},{"v":9.59074362767609,"d":"9.59"},"Transcript-dependent",{"v":0.970168031148888,"d":"0.97"}]
[null,11,"SYN3","O14994",{"v":9.32e-08,"d":"9.32E-08"},{"v":-0.0747598,"d":"-0.07"},{"v":0.000592277,"d":"5.92E-04"},{"v":2.37471E-4,"d":"2.37E-04"},{"v":-0.0496414,"d":"-0.05"},{"v":0.000221543,"d":"2.22E-04"},{"v":-17.66115149,"d":"-17.66"},{"v":3.40619466872704,"d":"3.41"},"Transcript-dependent",{"v":0.942189313831604,"d":"0.94"}]
[null,12,"ARHGEF10","O15013",{"v":2.9e-07,"d":"2.90E-07"},{"v":0.0780506,"d":"0.08"},{"v":1.70035E-3,"d":"1.70E-03"},{"v":0.000502832,"d":"5.03E-04"},{"v":0.0525117,"d":"0.05"},{"v":1.05525E-3,"d":"1.06E-03"},{"v":-17.47464099,"d":"-17.47"},{"v":3.23902491029794,"d":"3.24"},"Transcript-dependent",{"v":0.957616144715878,"d":"0.96"}]
[null,13,"PFAS","O15067",{"v":3.75e-21,"d":"3.75E-21"},{"v":0.0874333,"d":"0.09"},{"v":7.55e-17,"d":"7.55E-17"},{"v":2.04e-12,"d":"2.04E-12"},{"v":0.0648508,"d":"0.06"},{"v":8.21e-15,"d":"8.21E-15"},{"v":-20.23820191,"d":"-20.24"},{"v":8.73559889969818,"d":"8.74"},"Transcript-dependent",{"v":0.95527755079251,"d":"0.96"}]
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[null,398,"PLGRKT","Q9HBL7",{"v":5.56e-26,"d":"5.56E-26"},{"v":-0.577536,"d":"-0.58"},{"v":5.18e-15,"d":"5.18E-15"},{"v":4.91e-25,"d":"4.91E-25"},{"v":-0.56576,"d":"-0.57"},{"v":6e-25,"d":"6.00E-25"},{"v":-1.072714586,"d":"-1.07"},{"v":0.946006700540909,"d":"0.95"},"Transcript-independent",{"v":0.742931102507013,"d":"0.74"}]
[null,399,"NMRAL1","Q9HBL8",{"v":4.38e-23,"d":"4.38E-23"},{"v":-0.496648,"d":"-0.50"},{"v":1.29e-09,"d":"1.29E-09"},{"v":8.43e-24,"d":"8.43E-24"},{"v":-0.505353,"d":"-0.51"},{"v":2.53e-28,"d":"2.53E-28"},{"v":4.411031112,"d":"4.41"},{"v":-0.715646535879358,"d":"-0.72"},"Transcript-independent",{"v":0.605674139118484,"d":"0.61"}]
[null,400,"SNX15","Q9NRS6",{"v":1.87e-06,"d":"1.87E-06"},{"v":-0.0419393,"d":"-0.04"},{"v":0.0036049,"d":"3.60E-03"},{"v":0.000110594,"d":"1.11E-04"},{"v":-0.0345535,"d":"-0.03"},{"v":5.53e-08,"d":"5.53E-08"},{"v":-13.89450689,"d":"-13.89"},{"v":1.77188995951378,"d":"1.77"},"Transcript-independent",{"v":0.96938996975635,"d":"0.97"}]
[null,401,"HEBP1","Q9NRV9",{"v":1E-50,"d":"1.00E-50"},{"v":-0.734479,"d":"-0.73"},{"v":1.62e-41,"d":"1.62E-41"},{"v":1E-50,"d":"1.00E-50"},{"v":-0.734678,"d":"-0.73"},1.31E-74,{"v":5.008759479,"d":"5.01"},{"v":0,"d":"0.00"},"Transcript-independent",{"v":0.849604388305717,"d":"0.85"}]
[null,402,"STARD5","Q9NSY2",1.28E-10,{"v":-0.181607,"d":"-0.18"},{"v":9.39e-06,"d":"9.39E-06"},{"v":2.42e-10,"d":"2.42E-10"},{"v":-0.176731,"d":"-0.18"},{"v":4.16e-11,"d":"4.16E-11"},{"v":-0.171470987,"d":"-0.17"},{"v":0.276605396332563,"d":"0.28"},"Transcript-independent",{"v":0.772188068083102,"d":"0.77"}]
[null,403,"SIRT3","Q9NTG7",{"v":4.58E-7,"d":"4.58E-07"},{"v":0.0717446,"d":"0.07"},{"v":0.000270067,"d":"2.70E-04"},{"v":1.86E-7,"d":"1.86E-07"},{"v":0.0746639,"d":"0.07"},{"v":6.08e-09,"d":"6.08E-09"},{"v":1.602582242,"d":"1.60"},{"v":-0.391352533785953,"d":"-0.39"},"Transcript-independent",{"v":0.865146077689969,"d":"0.87"}]
[null,404,"WWOX","Q9NZC7",{"v":9.19e-10,"d":"9.19E-10"},{"v":-0.175276,"d":"-0.18"},{"v":9.15e-06,"d":"9.15E-06"},{"v":4.91e-09,"d":"4.91E-09"},{"v":-0.162214,"d":"-0.16"},{"v":2.19e-10,"d":"2.19E-10"},{"v":1.286041922,"d":"1.29"},{"v":0.727765980736857,"d":"0.73"},"Transcript-independent",{"v":0.572452979978988,"d":"0.57"}]
[null,405,"CPNE7","Q9UBL6",{"v":1.15E-6,"d":"1.15E-06"},{"v":-0.0774979,"d":"-0.08"},{"v":0.00325182,"d":"3.25E-03"},{"v":4.12e-06,"d":"4.12E-06"},{"v":-0.0696096,"d":"-0.07"},{"v":8.11e-06,"d":"8.11E-06"},{"v":-2.634908262,"d":"-2.63"},{"v":0.554199375679523,"d":"0.55"},"Transcript-independent",{"v":0.832257822033091,"d":"0.83"}]
[null,406,"PISD","Q9UG56",{"v":2.63e-08,"d":"2.63E-08"},{"v":-0.211367,"d":"-0.21"},{"v":1.06325E-3,"d":"1.06E-03"},{"v":2.83e-08,"d":"2.83E-08"},{"v":-0.213945,"d":"-0.21"},{"v":2.97e-08,"d":"2.97E-08"},{"v":0.185534876,"d":"0.19"},{"v":0.0318306870345326,"d":"0.03"},"Transcript-independent",{"v":0.783521533313779,"d":"0.78"}]
[null,407,"PCYOX1","Q9UHG3",{"v":3.43e-08,"d":"3.43E-08"},{"v":-0.0630508,"d":"-0.06"},{"v":4.39e-05,"d":"4.39E-05"},{"v":1.67e-08,"d":"1.67E-08"},{"v":-0.062936,"d":"-0.06"},{"v":5.58e-09,"d":"5.58E-09"},{"v":-1.406600046,"d":"-1.41"},{"v":-0.312577648895187,"d":"-0.31"},"Transcript-independent",{"v":0.616392289580232,"d":"0.62"}]
[null,408,"VWA7","Q9Y334",{"v":8.34e-21,"d":"8.34E-21"},{"v":-0.459609,"d":"-0.46"},{"v":3.89e-11,"d":"3.89E-11"},{"v":1.71e-09,"d":"1.71E-09"},{"v":-0.284118,"d":"-0.28"},{"v":5.55e-10,"d":"5.55E-10"},{"v":-1.731813892,"d":"-1.73"},{"v":11.3118300597544,"d":"11.31"},"Transcript-independent",{"v":0.966074156543688,"d":"0.97"}]
[null,409,"PPIL1","Q9Y3C6",1.84E-39,{"v":-0.563344,"d":"-0.56"},{"v":2.57e-20,"d":"2.57E-20"},3.96E-42,{"v":-0.565654,"d":"-0.57"},{"v":3.59e-40,"d":"3.59E-40"},{"v":0.526905174,"d":"0.53"},{"v":-2.66712263708403,"d":"-2.67"},"Transcript-independent",{"v":0.564731244144149,"d":"0.56"}]
[null,410,"NME7","Q9Y5B8",{"v":4.87e-08,"d":"4.87E-08"},{"v":0.069504,"d":"0.07"},{"v":0.000185471,"d":"1.85E-04"},{"v":4.28e-08,"d":"4.28E-08"},{"v":0.0695972,"d":"0.07"},{"v":3.28e-07,"d":"3.28E-07"},{"v":-1.011670981,"d":"-1.01"},{"v":-0.0560851922014622,"d":"-0.06"},"Transcript-independent",{"v":0.858177585978086,"d":"0.86"}]
[null,411,"GMPPB","Q9Y5P6",{"v":7.56e-08,"d":"7.56E-08"},{"v":0.0906467,"d":"0.09"},{"v":3.28e-05,"d":"3.28E-05"},{"v":6.77e-07,"d":"6.77E-07"},{"v":0.0833643,"d":"0.08"},{"v":2.03e-05,"d":"2.03E-05"},{"v":-1.820235591,"d":"-1.82"},{"v":0.952066873183938,"d":"0.95"},"Transcript-independent",{"v":0.911594046556599,"d":"0.91"}]

{"sheet":"Table S8A","index":9,"n_rows":8,"n_cols":22,"rows_kept":8,"merged":[[0,1,0,21],[1,1,1,21],[2,1,3,1],[2,2,2,5],[2,6,2,10],[2,11,2,13],[2,14,2,16],[2,17,2,21]]}
[null,"Table S8A. SMR analysis result with summary statistics of SCZ GWAS meta-analysis using protein expression as the exposure."]
[null,"A total of 461 significant cis-pQTLs were detected within a 1Mb window centered on the SCZ GWAS leading SNPs. We used 270 loci recently identified by SCZ GWAS meta-analysis (The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stephan Ripke,James TR Walters, Michael C O’Donovan.Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia.medRxiv.doi: https://doi.org/10.1101/2020.09.12.20192922.). After applying the HEIDI test (p value ≥ 0.05), we found 402 protein-disease associations. The list of assciations were further filtering by SMR (p value < 6.3 × 10−5 ; Bonferroni correction), resulting to 4 causal/pleoitropic associations.   "]
[null,"Index","Protein",{"$nulls":3},"SNP",{"$nulls":4},"GWAS",null,null,"pQTL",null,null,"SMR"]
[null,null,"Gene symbol","Uniprot ID","Protein chr","Protein pos","SNP chr","SNP pos","Ref ","Alt","Freq","GWAS effect size","GWAS se","p value GWAS","pQTL effect size","pQTL se","p value pQTL","SMR effect size","se SMR","p value SMR","p value HEIDI","N SNP HEIDI"]
[null,1,"P2RX7","Q99572",12,{"v":121570774,"d":"121,570,774"},12,{"v":121684176,"d":"121,684,176"},"C","G",{"v":0.810606,"d":"0.81"},{"v":-0.0515957,"d":"-0.05"},{"v":0.0093,"d":"0.01"},{"v":3.04e-08,"d":"3.04E-08"},{"v":-0.482538,"d":"-0.48"},{"v":0.0531828,"d":"0.05"},{"v":1.155764e-19,"d":"1.16E-19"},{"v":0.106926,"d":"0.11"},{"v":0.0225906,"d":"0.02"},{"v":2.21002e-06,"d":"2.21E-06"},{"v":0.172562899999999,"d":"0.17"},20]
[null,2,"DARS2","Q6PI48",1,{"v":173794368,"d":"173,794,368"},1,{"v":173666162,"d":"173,666,162"},"T","C",{"v":0.793561,"d":"0.79"},{"v":0.0473987,"d":"0.05"},{"v":0.0093,"d":"0.01"},{"v":3.036e-07,"d":"3.04E-07"},{"v":-0.116942,"d":"-0.12"},{"v":0.0145327,"d":"0.01"},{"v":8.496749e-16,"d":"8.50E-16"},{"v":-0.405318,"d":"-0.41"},{"v":0.0941361,"d":"0.09"},{"v":1.664884e-05,"d":"1.66E-05"},{"v":0.159472599999999,"d":"0.16"},20]
[null,3,"ARSA","P15289",22,{"v":51063576,"d":"51,063,576"},22,{"v":51145702,"d":"51,145,702"},"C","G",{"v":0.954545,"d":"0.95"},{"v":0.133201,"d":"0.13"},{"v":0.0264,"d":"0.03"},{"v":4.455e-07,"d":"4.46E-07"},{"v":-0.262053,"d":"-0.26"},{"v":0.0424787,"d":"0.04"},{"v":6.870597e-10,"d":"6.87E-10"},{"v":-0.508299,"d":"-0.51"},{"v":0.130147,"d":"0.13"},{"v":9.399489e-05,"d":"9.40E-05"},{"v":0.1381265,"d":"0.14"},6]
[null,4,"ACTR1B","P42025",2,{"v":98273324,"d":"98,273,324"},2,{"v":98275354,"d":"98,275,354"},"G","A",{"v":0.918561,"d":"0.92"},{"v":0.0865996,"d":"0.09"},{"v":0.0156,"d":"0.02"},{"v":2.992e-08,"d":"2.99E-08"},{"v":-0.100349,"d":"-0.10"},{"v":0.0159085,"d":"0.02"},{"v":2.828527e-10,"d":"2.83E-10"},{"v":-0.862984,"d":"-0.86"},{"v":0.207085,"d":"0.21"},{"v":3.082243E-5,"d":"3.08E-05"},{"v":0.569253499999999,"d":"0.57"},6]

{"sheet":"Table S8B","index":10,"n_rows":23,"n_cols":22,"rows_kept":23,"merged":[[0,1,0,21],[1,1,1,21],[2,1,3,1],[2,2,2,5],[2,6,2,10],[2,11,2,13],[2,14,2,16],[2,17,2,21]]}
[null,"Table S8B. SMR analysis result with summary statistics of SCZ GWAS meta-analysis using gene expression as the exposure."]
[null,"A total of 4,209 significant cis-pQTLs were detected within a 1Mb window centered on the SCZ GWAS leading SNPs. We used 270 loci recently identified by SCZ GWAS meta-analysis (The Schizophrenia Working Group of the Psychiatric Genomics Consortium, Stephan Ripke,James TR Walters, Michael C O’Donovan.Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia.medRxiv.doi: https://doi.org/10.1101/2020.09.12.20192922.). After applying the HEIDI test (p value ≥ 0.05), we found 3,281 protein-disease associations. The list of assciations were further filtering by SMR (p value < 5.3 × 10−6; Bonferroni correction), resulting to 19 causal/pleoitropic associations.   "]
[null,"Index","Protein",{"$nulls":3},"SNP",{"$nulls":4},"GWAS",null,null,"eQTL",null,null,"SMR"]
[null,null,"Gene symbol","Ensembl ID","Protein chr","Protein pos","Top SNP chr","Top SNP pos","Ref ","Alt","Freq","b GWAS","se GWAS","p value GWAS","b eQTL","se eQTL","p value eQTL","b SMR","se SMR","p value SMR","p value HEIDI","N SNP HEIDI"]
[null,1,"LRRC37A2","ENSG00000238083",17,{"v":44588878,"d":"44,588,878"},17,{"v":44862347,"d":"44,862,347"},"G","A",{"v":0.763258,"d":"0.76"},{"v":0.0493043,"d":"0.05"},{"v":0.0093,"d":"0.01"},{"v":1.294e-07,"d":"1.29E-07"},{"v":0.758749,"d":"0.76"},{"v":0.065278,"d":"0.07"},{"v":3.136061e-31,"d":"3.14E-31"},{"v":0.0649811,"d":"0.06"},{"v":0.0134718,"d":"0.01"},{"v":1.410646e-06,"d":"1.41E-06"},{"v":0.2288828,"d":"2.29E-01"},15]
[null,2,"SNORA38","ENSG00000200816",6,{"v":31590857,"d":"31,590,857"},6,{"v":31820400,"d":"31,820,400"},"C","T",{"v":0.795455,"d":"0.80"},{"v":-0.0618967,"d":"-0.06"},{"v":0.0101,"d":"0.01"},{"v":1.022E-9,"d":"1.02E-09"},{"v":-1.3824,"d":"-1.38"},{"v":0.170939,"d":"0.17"},{"v":6.109437e-16,"d":"6.11E-16"},{"v":0.0447748,"d":"0.04"},{"v":9.16696E-3,"d":"0.01"},{"v":1.037606E-6,"d":"1.04E-06"},{"v":0.1193493,"d":"1.19E-01"},9]
[null,3,"SLC9C2","ENSG00000162753",1,{"v":173469604,"d":"173,469,604"},1,{"v":173646773,"d":"173,646,773"},"G","A",{"v":0.899621,"d":"0.90"},{"v":0.0653007,"d":"0.07"},{"v":0.011,"d":"0.01"},{"v":2.875e-09,"d":"2.88E-09"},{"v":0.470962,"d":"0.47"},{"v":0.0615793,"d":"0.06"},{"v":2.040342E-14,"d":"2.04E-14"},{"v":0.138654,"d":"0.14"},{"v":0.0295668,"d":"0.03"},{"v":2.738522e-06,"d":"2.74E-06"},{"v":0.6912247,"d":"6.91E-01"},20]
[null,4,"SFMBT1","ENSG00000163935",3,{"v":52937589,"d":"52,937,589"},3,{"v":53082937,"d":"53,082,937"},"C","T",{"v":0.761364,"d":"0.76"},{"v":0.0575045,"d":"0.06"},{"v":0.009,"d":"0.01"},{"v":1.688E-10,"d":"1.69E-10"},{"v":0.0695287,"d":"0.07"},{"v":0.00956091,"d":"0.01"},{"v":3.537171e-13,"d":"3.54E-13"},{"v":0.827061,"d":"0.83"},{"v":0.172307,"d":"0.17"},{"v":1.587331E-6,"d":"1.59E-06"},{"v":0.2007181,"d":"2.01E-01"},6]
[null,5,"FTCDNL1","ENSG00000226124",2,{"v":200625268,"d":"200,625,268"},2,{"v":200715388,"d":"200,715,388"},"G","T",{"v":0.823864,"d":"0.82"},{"v":-0.0763961,"d":"-0.08"},{"v":0.0097,"d":"0.01"},{"v":3.269e-15,"d":"3.27E-15"},{"v":-0.177638,"d":"-0.18"},{"v":0.0234398,"d":"0.02"},{"v":3.496585e-14,"d":"3.50E-14"},{"v":0.430066,"d":"0.43"},{"v":0.0787536,"d":"0.08"},{"v":4.737173e-08,"d":"4.74E-08"},{"v":0.415957399999999,"d":"4.16E-01"},20]
[null,6,"ANKRD45","ENSG00000183831",1,{"v":173578701,"d":"173,578,701"},1,{"v":173646773,"d":"173,646,773"},"G","A",{"v":0.899621,"d":"0.90"},{"v":0.0653007,"d":"0.07"},{"v":0.011,"d":"0.01"},{"v":2.875e-09,"d":"2.88E-09"},{"v":-0.207193,"d":"-0.21"},{"v":0.0268998,"d":"0.03"},{"v":1.335442e-14,"d":"1.34E-14"},{"v":-0.315169,"d":"-0.32"},{"v":0.0670292,"d":"0.07"},{"v":2.576787e-06,"d":"2.58E-06"},{"v":0.245830799999999,"d":"2.46E-01"},14]
[null,7,"HLA-DMB","ENSG00000242574",6,{"v":32902407,"d":"32,902,407"},6,{"v":32963948,"d":"32,963,948"},"G","T",{"v":0.933712,"d":"0.93"},{"v":0.166404,"d":"0.17"},{"v":0.0177,"d":"0.02"},{"v":4.386E-21,"d":"4.39E-21"},{"v":0.443498,"d":"0.44"},{"v":0.0692632,"d":"0.07"},{"v":1.522754E-10,"d":"1.52E-10"},{"v":0.375208,"d":"0.38"},{"v":0.0708981,"d":"0.07"},{"v":1.208445e-07,"d":"1.21E-07"},{"v":0.13356,"d":"1.34E-01"},19]
[null,8,"HLA-DMA","ENSG00000204257",6,{"v":32916391,"d":"32,916,391"},6,{"v":32963948,"d":"32,963,948"},"G","T",{"v":0.933712,"d":"0.93"},{"v":0.166404,"d":"0.17"},{"v":0.0177,"d":"0.02"},{"v":4.386E-21,"d":"4.39E-21"},{"v":0.455358,"d":"0.46"},{"v":0.0582607,"d":"0.06"},{"v":5.458673e-15,"d":"5.46E-15"},{"v":0.365435,"d":"0.37"},{"v":0.060803,"d":"0.06"},{"v":1.853457E-9,"d":"1.85E-09"},{"v":0.0541049399999999,"d":"5.41E-02"},20]
[null,9,"RP11-165J3.6","ENSG00000227603",9,{"v":96197615,"d":"96,197,615"},9,{"v":96243745,"d":"96,243,745"},"A","G",{"v":0.875,"d":"0.88"},{"v":-0.0573961,"d":"-0.06"},{"v":0.0109,"d":"0.01"},{"v":1.409E-7,"d":"1.41E-07"},{"v":0.512869,"d":"0.51"},{"v":0.0494323,"d":"0.05"},{"v":3.21617e-25,"d":"3.22E-25"},{"v":-0.111912,"d":"-0.11"},{"v":0.0238335,"d":"0.02"},{"v":2.658811e-06,"d":"2.66E-06"},{"v":0.476455699999999,"d":"4.76E-01"},20]
[null,10,"FOXN2","ENSG00000170802",2,{"v":48541777,"d":"48,541,777"},2,{"v":48573895,"d":"48,573,895"},"G","C",{"v":0.890152,"d":"0.89"},{"v":0.0728972,"d":"0.07"},{"v":0.0139,"d":"0.01"},{"v":1.679e-07,"d":"1.68E-07"},{"v":0.125421,"d":"0.13"},{"v":0.0122286,"d":"0.01"},{"v":1.107777E-24,"d":"1.11E-24"},{"v":0.58122,"d":"0.58"},{"v":0.124475,"d":"0.12"},{"v":3.02103e-06,"d":"3.02E-06"},{"v":0.0616735799999999,"d":"6.17E-02"},20]
[null,11,"BRD2","ENSG00000204256",6,{"v":32936438,"d":"32,936,438"},6,{"v":32963948,"d":"32,963,948"},"G","T",{"v":0.933712,"d":"0.93"},{"v":0.166404,"d":"0.17"},{"v":0.0177,"d":"0.02"},{"v":4.386E-21,"d":"4.39E-21"},{"v":0.134276,"d":"0.13"},{"v":0.0177211,"d":"0.02"},{"v":3.531601E-14,"d":"3.53E-14"},{"v":1.23927,"d":"1.24"},{"v":0.210061,"d":"0.21"},{"v":3.644518e-09,"d":"3.64E-09"},{"v":0.1441562,"d":"1.44E-01"},17]
[null,12,"ZNF823","ENSG00000197933",19,{"v":11832081,"d":"11,832,081"},19,{"v":11849736,"d":"11,849,736"},"C","T",{"v":0.945076,"d":"0.95"},{"v":-0.111703,"d":"-0.11"},{"v":0.0177,"d":"0.02"},{"v":3.066e-10,"d":"3.07E-10"},{"v":0.217697,"d":"0.22"},{"v":0.029172,"d":"0.03"},{"v":8.48677e-14,"d":"8.49E-14"},{"v":-0.513111,"d":"-0.51"},{"v":0.106481,"d":"0.11"},{"v":1.444352E-6,"d":"1.44E-06"},"NA","NA"]
[null,13,"NOTCH4","ENSG00000204301",6,{"v":32162621,"d":"32,162,621"},6,{"v":32176782,"d":"32,176,782"},"G","T",{"v":0.797348,"d":"0.80"},{"v":0.094901,"d":"0.09"},0.01,{"v":3.159e-21,"d":"3.16E-21"},{"v":-0.140984,"d":"-0.14"},{"v":0.025384,"d":"0.03"},{"v":2.791408E-8,"d":"2.79E-08"},{"v":-0.673133,"d":"-0.67"},{"v":0.140427,"d":"0.14"},{"v":1.639223e-06,"d":"1.64E-06"},{"v":0.6941171,"d":"6.94E-01"},20]
[null,14,"CUL9","ENSG00000112659",6,{"v":43149914,"d":"43,149,914"},6,{"v":43152573,"d":"43,152,573"},"A","G",{"v":0.848485,"d":"0.85"},{"v":0.061603,"d":"0.06"},{"v":0.0101,"d":"0.01"},{"v":1.169E-9,"d":"1.17E-09"},{"v":-0.0784197,"d":"-0.08"},{"v":0.00776658,"d":"0.01"},{"v":5.69208e-24,"d":"5.69E-24"},{"v":-0.785555,"d":"-0.79"},{"v":0.150469,"d":"0.15"},{"v":1.782298e-07,"d":"1.78E-07"},{"v":0.1056634,"d":"1.06E-01"},20]
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{"sheet":"Table S9","index":11,"n_rows":6350,"n_cols":100,"rows_kept":562,"cut":true,"merged":[[0,1,0,10],[1,1,1,15],[2,1,2,15],[2,16,2,36],[2,38,2,57],[2,59,2,78],[2,80,2,99]],"bounds":{"rows_first":250,"rows_last":62,"rows_between":250,"halvings":3}}
[null,"Table S9. Integrating multi-omic data sets to prioritize candidate proteins for SCZ GWAS loci"]
[null,"Proteins were prioritized using five data sets, including cis-pQTLs, cis-eQTLs, colocalization of cis-pQTLs and cis-eQTLs, functional score inferred by GeneCards, and protein-protein network. GIFtS: GeneCards Inferred Functionality Score. Network score was calculated by the number of downstream SCZ risk genes. Cell-type-specific expression data were downloaded from Supplementary Material of Ruzicka et al. (doi: https://doi.org/10.1101/2020.11.06.20225342). The paper annotated 20 cell types/states using snRNA-seq data from 24 schizophrenia cases and 24 controls. Full description of each cell type can be found in the bottom of this spreadsheet. Gene expression in each cell type were summed from all cells across all 48 samples. Differentially expressed genes (DEGs) between SCZ and control samples across each cell type were tested using t-test.  "]
[null,"Ranking",{"$nulls":14},"Differential expression between SCZ and control samples (log2 Fold change)",{"$nulls":21},"Differential expression between SCZ and control samples (-log10 p value)",{"$nulls":20},"Cell-type abundance (log2TPM)",{"$nulls":20},"Cell-type abundance (-log10 p value)"]
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[null,6326,"AHDC1",{"v":0.00138971,"d":"1.39E-03"},{"v":0.708314942,"d":"7.08E-01"},6590,{"v":0.000648704,"d":"6.49E-04"},{"v":0.27792204,"d":"2.78E-01"},8394,"NA","NA",0.08,4485,"NA","NA",{"v":0.992141178,"d":"9.92E-01"},{"v":-1.0096119505812,"d":"-1.01"},{"v":-3.79751117364515,"d":"-3.80"},{"v":-0.684657893958635,"d":"-0.68"},{"v":-0.623485008332901,"d":"-0.62"},{"v":-0.499178845167832,"d":"-0.50"},{"v":-1.30939714098517,"d":"-1.31"},{"v":-0.609537150241618,"d":"-0.61"},{"v":-1.39156153786586,"d":"-1.39"},{"v":-0.769343145763928,"d":"-0.77"},{"v":-1.33472953021155,"d":"-1.33"},{"v":-0.82341559685091,"d":"-0.82"},{"v":-0.693367318552676,"d":"-0.69"},{"v":-0.0229029379600729,"d":"-0.02"},{"v":-0.675280380169954,"d":"-0.68"},{"v":-0.00423046158538209,"d":"-0.00"},{"v":0.0554558054317082,"d":"0.06"},{"v":-0.00861671874662928,"d":"-0.01"},{"v":0.0357941117058314,"d":"0.04"},{"v":0.47190022375056,"d":"0.47"},{"v":-1.4248717387453,"d":"-1.42"},"SZTR",null,{"v":0.276038370367657,"d":"0.28"},{"v":0.579315273347528,"d":"0.58"},{"v":0.207816606784379,"d":"0.21"},{"v":0.0894911195524183,"d":"0.09"},{"v":0.295155086462249,"d":"0.30"},{"v":0.242281402860677,"d":"0.24"},{"v":0.0287479393287718,"d":"0.03"},{"v":0.424149974163294,"d":"0.42"},{"v":0.390196156901478,"d":"0.39"},{"v":0.642786272643888,"d":"0.64"},{"v":0.866564695983214,"d":"0.87"},{"v":0.415640445111851,"d":"0.42"},{"v":0.0255446230824687,"d":"0.03"},{"v":0.223912995143572,"d":"0.22"},{"v":0.145767356409296,"d":"0.15"},{"v":0.203099746141717,"d":"0.20"},{"v":0.189516755473395,"d":"0.19"},{"v":0.0868625004381465,"d":"0.09"},{"v":0.417158019632967,"d":"0.42"},{"v":0.15069508219465,"d":"0.15"},null,{"v":2.29621820177254,"d":"2.30"},{"v":3.77544901646322,"d":"3.78"},{"v":4.65014778623981,"d":"4.65"},{"v":4.41186886303291,"d":"4.41"},{"v":4.57229940485467,"d":"4.57"},{"v":4.6466083581408,"d":"4.65"},{"v":4.26167787298162,"d":"4.26"},{"v":4.60574616237049,"d":"4.61"},{"v":4.87137043798755,"d":"4.87"},{"v":3.79568418386945,"d":"3.80"},{"v":3.65644323915542,"d":"3.66"},{"v":3.77422745028163,"d":"3.77"},{"v":3.60747319166474,"d":"3.61"},{"v":3.49115245995422,"d":"3.49"},{"v":2.93380969229066,"d":"2.93"},{"v":3.65587891598323,"d":"3.66"},{"v":2.98183181112658,"d":"2.98"},{"v":0.601474632411301,"d":"0.60"},{"v":1.8540505858731,"d":"1.85"},{"v":1.92694602386434,"d":"1.93"},null,{"v":9.865328474,"d":"9.87"},{"v":0.186248195,"d":"0.19"},{"v":12.5977551,"d":"12.60"},{"v":5.531820169,"d":"5.53"},{"v":9.803444862,"d":"9.80"},{"v":12.45873164,"d":"12.46"},{"v":2.928039279,"d":"2.93"},{"v":10.93826609,"d":"10.94"},{"v":24.10579772,"d":"24.11"},{"v":0.126447132,"d":"0.13"},{"v":0.623984569,"d":"0.62"},{"v":0.189998579,"d":"0.19"},{"v":0.843957558,"d":"0.84"},{"v":1.44666771,"d":"1.45"},{"v":5.254346178,"d":"5.25"},{"v":0.626394283,"d":"0.63"},{"v":4.897217296,"d":"4.90"},{"v":17.89119517,"d":"17.89"},{"v":12.61786315,"d":"12.62"},{"v":12.19681633,"d":"12.20"}]
[null,null,"Note: "]
[null,null,"Celltype","Description"]
[null,null,"Endo","endothelial cells"]
[null,null,"Ex-L2/3","superficial layer excitatory neurons (excitatory neuron, cortical layers: superficial)"]
[null,null,"Ex-L4","superficial layer excitatory neurons (excitatory neuron, cortical layers: intermediate)"]
[null,null,"Ex-L4/5","superficial layer excitatory neurons (excitatory neuron, cortical layers: intermediate)"]
[null,null,"Ex-L5","(excitatory neuron, cortical layers: deep)"]
[null,null,"Ex-L5/6","cortico-fugal projection neurons (excitatory neuron, cortical layers: deep)"]
[null,null,"Ex-L5/6-CCa","cortico-cortical projection neurons, enriched for genes involved in dopamine receptor signaling pathway (excitatory neuron, cortical layers: deep)"]
[null,null,"Ex-L5/6-CCb","cortico-cortical projection neurons, enriched for many key genes in glutamate signaling (excitatory neuron, cortical layers: deep)"]
[null,null,"In-PV-Basket","parvalbumin(PV)-expressing basket cells (inhibitory neuron, originate in the medial ganglionic eminence)"]
[null,null,"In-PV-Chandelier","parvalbumin(PV)-expressing Chandelier cells (inhibitory neuron, originate in the medial ganglionic eminence)"]
[null,null,"In-SST","somatostatin(SST) expressing interneurons (inhibitory neuron, originate in the medial ganglionic eminence)"]
[null,null,"In-Reelin","5HT3aR-expressing cells(Reelin+) (inhibitory neuron, originate in the caudal ganglionic eminence)"]
[null,null,"In-VIP","5HT3aR-expressing cells(VIP+) (inhibitory neuron, originate in the caudal ganglionic eminence)"]
[null,null,"In-Rosehip","Rosehip neurons, inhibitory GABAergic neurons present in the molecular(first) layer of human cerebral cortex. (inhibitory neuron, originate in the caudal ganglionic eminence)"]
[null,null,"Ast","astrocyte (Glial)"]
[null,null,"Mic","microglia (Glial)"]
[null,null,"Oli","oligodendrocyte (Glial)"]
[null,null,"OPC","oligodendrocyte precursor cell (Glial)"]

{"sheet":"Table S10","index":12,"n_rows":985,"n_cols":12,"rows_kept":985,"merged":[[0,1,0,10],[1,1,1,11]]}
[null,"Table S10. SCZ GWAS risk genes collected from 9 published papers"]
[null,"We extracted a total of 971 risk genes in GWAS loci reported by a list of 9 papers (see the bottom of the spreadsheet) to curated a catalog of SCZ and BP risk genes. "]
[null,"Gene symbol","BIP2012","BIP2019","BIP2021","SCZ&BIP2018","SCZ2011","SCZ2013","SCZ2014","SCZ2018","SCZ2021","Sum"]
[null,"CACNA1C",1,1,0,1,1,1,1,1,1,{"$f":"SUM(C4:K4)","v":8}]
[null,"MAD1L1",1,0,0,1,1,1,1,1,1,7]
[null,"ITIH3",1,1,0,1,1,1,1,0,0,6]
[null,"BCL11B",0,0,1,1,0,0,1,1,1,5]
[null,"GATAD2A",0,1,0,1,0,0,1,1,1,5]
[null,"TCF4",0,0,0,1,1,1,1,1,0,5]
[null,"AKT3",0,0,0,0,1,1,1,1,1,5]
[null,"CACNB2",0,0,1,1,0,1,1,1,0,5]
[null,"CSMD1",0,0,0,0,1,1,1,1,1,5]
[null,"FURIN",0,0,1,1,0,0,1,1,1,5]
[null,"GRIN2A",0,1,0,1,0,0,1,1,1,5]
[null,"TSNARE1",0,0,0,1,0,1,1,1,1,5]
[null,"ZNF804A",0,0,0,1,0,1,1,1,1,5]
[null,"NAB2",0,0,0,1,0,0,1,1,1,4]
[null,"NCAN",0,1,0,1,0,0,1,1,0,4]
[null,"SATB2",0,0,0,1,0,1,1,1,0,4]
[null,"ADAMTSL3",0,1,0,1,0,0,1,1,0,4]
[null,"CNTN4",0,0,0,1,0,0,1,1,1,4]
[null,"DPYD",0,0,0,0,1,1,1,1,0,4]
[null,"GIGYF2",0,0,0,1,0,1,1,1,0,4]
[null,"GNL3",1,1,0,0,1,0,1,0,0,4]
[null,"IMMP2L",0,0,0,1,0,0,1,1,1,4]
[null,"ITIH1",1,1,0,1,0,0,1,0,0,4]
[null,"ITIH4",1,1,0,0,1,0,1,0,0,4]
[null,"MIR137",0,0,0,0,1,1,1,1,0,4]
[null,"MMP16",0,0,0,0,1,1,1,1,0,4]
[null,"NEK4",1,1,0,0,1,0,1,0,0,4]
[null,"NRGN",0,0,0,1,1,0,1,1,0,4]
[null,"NT5C2",0,0,0,0,1,1,1,1,0,4]
[null,"SDCCAG8",0,0,0,1,0,1,1,1,0,4]
[null,"SLC39A8",0,0,0,1,0,0,1,1,1,4]
[null,"SNAP91",0,0,0,1,0,0,1,1,1,4]
[null,"SRPK2",0,1,0,1,0,0,1,1,0,4]
[null,"THOC7",0,0,0,1,0,0,1,1,1,4]
[null,"ANK3",1,1,0,0,1,0,0,0,0,3]
[null,"C2orf47",0,0,0,1,0,0,1,1,0,3]
[null,"CILP2",0,1,0,0,0,0,1,1,0,3]
[null,"CNNM4",1,1,0,1,0,0,0,0,0,3]
[null,"CNOT1",0,0,0,1,0,0,1,1,0,3]
[null,"HAPLN4",0,1,0,0,0,0,1,1,0,3]
[null,"KDM3B",0,0,1,1,0,0,1,0,0,3]
[null,"KLC1",0,0,0,1,0,1,1,0,0,3]
[null,"LMAN2L",1,1,0,1,0,0,0,0,0,3]
[null,"MAU2",0,1,0,0,0,0,1,1,0,3]
[null,"MHC",0,0,1,0,0,0,1,1,0,3]
[null,"NDUFA13",0,1,0,0,0,0,1,1,0,3]
[null,"NLGN4X",0,0,0,0,0,0,1,1,1,3]
[null,"PACS1",1,1,0,1,0,0,0,0,0,3]
[null,"PAK6",0,0,0,0,0,0,1,1,1,3]
[null,"PBX4",0,1,0,0,0,0,1,1,0,3]
[null,"PC",1,1,0,1,0,0,0,0,0,3]
[null,"PCGEM1",0,0,1,0,1,0,1,0,0,3]
[null,"PJA1",0,0,0,0,0,0,1,1,1,3]
[null,"PPP1R13B",0,0,0,1,0,0,1,1,0,3]
[null,"RFT1",1,1,0,0,0,0,0,1,0,3]
[null,"RIMS1",0,1,0,0,0,0,1,1,0,3]
[null,"SFMBT1",1,1,0,0,0,0,0,1,0,3]
[null,"SPTBN2",1,1,0,1,0,0,0,0,0,3]
[null,"SUGP1",0,1,0,0,0,0,1,1,0,3]
[null,"TCF20",0,0,0,1,0,0,1,1,0,3]
[null,"TM6SF2",0,1,0,0,0,0,1,1,0,3]
[null,"TSSK6",0,1,0,0,0,0,1,1,0,3]
[null,"ABCB9",0,0,0,1,0,0,1,1,0,3]
[null,"ANP32E",0,1,0,0,0,0,1,1,0,3]
[null,"ARL6IP4",0,0,0,1,0,0,1,1,0,{"$f":"SUM(C68:K68)","v":3}]
[null,"ASPHD1",0,0,0,0,0,0,1,1,1,3]
[null,"ATG13",0,0,0,0,0,0,1,1,1,3]
[null,"ATP2A2",0,0,0,0,0,0,1,1,1,3]
[null,"ATXN7",0,0,0,1,0,0,1,1,0,3]
[null,"C12orf65",0,0,0,0,0,1,1,1,0,3]
[null,"C2orf82",0,0,0,0,0,1,1,1,0,3]
[null,"C3orf49",0,0,0,1,0,0,1,1,0,3]
[null,"CA14",0,1,0,0,0,0,1,1,0,3]
[null,"CACNA1I",0,0,0,0,0,0,1,1,1,3]
[null,"CHRNA3",0,0,0,1,0,0,1,1,0,3]
[null,"CLCN3",0,0,0,0,0,0,1,1,1,3]
[null,"CNNM2",0,0,0,0,1,0,1,1,0,3]
[null,"COQ10B",0,0,0,0,0,1,1,1,0,3]
[null,"DFNA5",0,0,0,1,0,0,1,1,0,3]
[null,"DGKI",0,0,0,1,0,0,1,1,0,3]
[null,"ESAM",0,0,0,0,0,0,1,1,1,3]
[null,"ETF1",0,0,0,1,0,0,1,1,0,3]
[null,"GID4",0,0,0,1,0,0,1,1,0,3]
[null,"GLT8D1",1,1,0,0,0,0,1,0,0,3]
[null,"GOLGA6L4",0,1,0,0,0,0,1,1,0,3]
[null,"GPM6A",0,0,0,0,0,0,1,1,1,3]
[null,"GRM3",0,0,0,1,0,0,1,1,0,3]
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[]
[null,"References:"]
[null,"BIP2012: Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 43 977–983 (2011). https://doi.org/10.1038/ng.943."]
[null,"BIP2019: Stahl E.A. Breen G. Forstner A.J. et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet 51 793–803 (2019). https://doi.org/10.1038/s41588-019-0397-8."]
[null,"BIP2021: Mullins N. Forstner A.J. O’Connell K.S. et al. Genome-wide association study of more than 40000 bipolar disorder cases provides new insights into the underlying biology. Nat Genet 53 817–829 (2021). https://doi.org/10.1038/s41588-021-00857-4."]
[null,"SCZ&BIP2018: Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium.  Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium (2018). Genomic Dissection of Bipolar Disorder and Schizophrenia Including 28 Subphenotypes. Cell 173(7) 1705–1715.e16. https://doi.org/10.1016/j.cell.2018.05.046. "]
[null,"SCZ2011: The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat Genet 43 969–976 (2011). https://doi.org/10.1038/ng.940. "]
[null,"SCZ2013: Ripke S. O'Dushlaine C. Chambert K. et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 45 1150–1159 (2013). https://doi.org/10.1038/ng.2742."]
[null,"SCZ2014: Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511 421–427 (2014). https://doi.org/10.1038/nature13595."]
[null,"SCZ2018: Pardiñas A.F. Holmans P. Pocklington A.J. et al. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nat Genet 50 381–389 (2018). https://doi.org/10.1038/s41588-018-0059-2. "]
[null,"SCZ2021: The Schizophrenia Working Group of the Psychiatric Genomics Consortium Stephan RipkeJames TR Walters Michael C O’Donovan.Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia.medRxiv.doi: https://doi.org/10.1101/2020.09.12.20192922."]