{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["26_Common_features_paths_noFC"],"read":"whole","date_system":"1900","formulas":"cached_only"}

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["feature","names","sign","TCGA-BRCA","TCGA-KIRC","TCGA-LUAD"]
["P-hsa04261-52","Adrenergic signaling in cardiomyocytes: MAPK14","DOWN","2.70160412063711e-54","2.08511157444828e-60","2.7981260451209e-59"]
["P-hsa04970-32","Salivary secretion: RYR3","DOWN","2.74617406221473e-84","1.49670266486506e-43","1.00467766900696e-77"]
["P-hsa04919-28","Thyroid hormone signaling pathway: RCAN1","DOWN","1.88287201031844e-76","2.34545484994459e-60","4.59754319866062e-42"]
["P-hsa05205-337","Proteoglycans in cancer: CTNNB1**","DOWN","6.20596412203484e-65","6.17492262748806e-81","1.06348422071508e-38"]
["P-hsa04261-4","Adrenergic signaling in cardiomyocytes: SLC8A1","DOWN","1.74038224343671e-38","2.4746455416549e-48","7.77311292727341e-78"]
["P-hsa04261-73","Adrenergic signaling in cardiomyocytes: KCNE1","DOWN","1.60590830089824e-36","5.17916702942976e-53","1.1149079163056e-62"]
["P-hsa05166-64","HTLV-I infection: CCNB2","UP","2.21548226170674e-55","6.4133314515741e-36","5.64344966311913e-50"]
["P-hsa04110-59 15 16 17 18 19 20","Cell cycle: CDC45 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2","UP","3.18978785939793e-46","1.43706201027532e-54","5.87038468270597e-35"]
["P-hsa04261-20","Adrenergic signaling in cardiomyocytes: ATP1B4","DOWN","6.57691076159224e-34","1.11270287924901e-57","4.0129229728603e-45"]
["P-hsa05010-47","Alzheimer's disease: Nitric oxide","DOWN","5.12819558762747e-33","3.12074982145288e-71","4.7184393173587e-45"]
["P-hsa04913-21","Ovarian steroidogenesis: CYP17A1","DOWN","1.8459576342398e-31","2.6943230272233e-45","2.05928071218925e-37"]
["P-hsa04913-22","Ovarian steroidogenesis: CYP17A1*","DOWN","1.8459576342398e-31","2.6943230272233e-45","2.05928071218925e-37"]
["P-hsa05200-189","Pathways in cancer: BIRC5","UP","9.09585569766928e-31","3.00760404030785e-54","9.60617184270414e-35"]
["P-hsa04713-61","Circadian entrainment: FOS","DOWN","2.16886224602389e-81","3.19380741275396e-30","6.43313566249446e-55"]
["P-hsa04261-23","Adrenergic signaling in cardiomyocytes: SLC9A1","DOWN","6.80899077991266e-30","2.41016610632279e-41","1.50389423964099e-60"]
["P-hsa04261-72","Adrenergic signaling in cardiomyocytes: ATP2B1","DOWN","8.23196775627409e-49","2.49176725284152e-29","8.11382236680709e-75"]
["P-hsa05210-21","Colorectal cancer: BIRC5","UP","4.27995736701308e-37","3.99623985843487e-38","3.69280188980116e-29"]
["P-hsa04960-3","Aldosterone-regulated sodium reabsorption: SCNN1A","DOWN","3.23804419552002e-67","1.73896806347485e-112","8.38425897196542e-29"]
["P-hsa04152-78","AMPK signaling pathway: CCNA2","UP","4.46118241381785e-62","4.76162138026755e-50","5.06948656974203e-28"]
["P-hsa04740-21","Olfactory transduction: PDE1A","DOWN","3.88155137603814e-67","6.52334820624161e-61","2.95519663838828e-27"]
["P-hsa04750-40","Inflammatory mediator regulation of TRP channels: Arachidonate","DOWN","5.73059685768971e-30","5.96668517682858e-39","1.59269557442979e-26"]
["P-hsa04530-5 10","Tight junction: IGSF5 MAGI1","DOWN","6.2665284849083e-26","1.10791364689117e-27","9.2568933767413e-31"]
["P-hsa05166-65","HTLV-I infection: PTTG2","UP","2.55698046026513e-65","4.21100262771319e-46","7.25937790635209e-26"]
["P-hsa04152-35","AMPK signaling pathway: PFKFB1","DOWN","3.14143365456671e-57","1.66500171120593e-41","5.25831633321821e-25"]
["P-hsa05110-51","Vibrio cholerae infection: PDIA4","UP","1.99120998871989e-24","9.18640286797735e-28","3.27922238280652e-46"]
["P-hsa04211-56","Longevity regulating pathway - mammal: CAT","DOWN","1.58729548038905e-56","3.22629924891499e-24","8.23733026779451e-64"]
["P-hsa05169-45","Epstein-Barr virus infection: RB1","DOWN","3.72088000583968e-24","1.59820691823812e-38","2.27671776433939e-36"]
["P-hsa04530-5 15","Tight junction: IGSF5 MPDZ","DOWN","1.87949875635299e-26","2.28475665989805e-22","2.40509627067343e-29"]
["P-hsa05205-304","Proteoglycans in cancer: MAPK1*****","DOWN","1.69797659518239e-50","9.56892128392056e-78","5.42518642579896e-22"]
["P-hsa04970-18","Salivary secretion: VAMP2","DOWN","6.07666268209099e-55","5.6722536342371e-22","8.18847815825552e-80"]
["P-hsa03320-9","PPAR signaling pathway: PCK1","DOWN","2.89919037252364e-55","5.88276716261272e-22","2.99101567816191e-26"]
["P-hsa04020-8","Calcium signaling pathway: PDE1A","DOWN","5.81339187109912e-75","6.49060825300828e-60","2.02677219615632e-21"]
["P-hsa04713-60","Circadian entrainment: PER1","DOWN","8.2992548060164e-77","2.10663360021286e-21","1.87341085321966e-54"]
["P-hsa04114-80","Oocyte meiosis: CDC25C*","UP","3.9595054771827e-74","6.45451071889997e-78","4.45378774122651e-21"]
["P-hsa04924-49","Renin secretion: PDE1A","DOWN","5.84913289155441e-73","1.29144957926274e-60","1.15079596210011e-20"]
["P-hsa05200-168","Pathways in cancer: E2F1","UP","1.44087742473387e-20","4.18695948034518e-38","1.22987855152902e-25"]
["P-hsa04014-26","Ras signaling pathway: PRKCA","DOWN","9.02119268039185e-22","1.91761351064848e-23","2.21804801491748e-20"]
["P-hsa04010-120","MAPK signaling pathway: NFATC1","DOWN","2.45369361375342e-20","3.29655948997225e-46","1.73072597521474e-24"]
["P-hsa04110-10 11 12 13 14 9 15 16 17 18 19 20","Cell cycle: ORC3 ORC5 ORC4 ORC2 ORC1 ORC6 MCM7 MCM6 MCM5 MCM4 MCM3 MCM2","UP","5.76357455145655e-34","2.6983758120999e-20","2.21244077529534e-37"]
["P-hsa04726-10","Serotonergic synapse: PRKACA","DOWN","8.19905101511222e-31","3.97745545342343e-65","2.70445406182397e-20"]
["P-hsa05010-61","Alzheimer's disease: GAPDH","UP","3.55900195627032e-20","3.01156995113169e-29","2.95155824042885e-33"]
["P-hsa04976-16","Bile secretion: CFTR","DOWN","7.17998241235448e-56","1.32384568145948e-33","6.21333404373234e-20"]
["P-hsa04152-54","AMPK signaling pathway: SLC2A4*","DOWN","1.17694998434669e-101","5.88798497249251e-30","8.05826479841769e-20"]
["P-hsa03320-28","PPAR signaling pathway: ACSL1","DOWN","9.73331494140852e-62","7.72253833725928e-49","1.58253478445433e-19"]
["P-hsa05200-205","Pathways in cancer: SLC2A1","UP","1.65844510696243e-19","1.16680978123172e-24","5.46934591818725e-33"]
["P-hsa04010-119","MAPK signaling pathway: NFATC3","DOWN","2.47839373266809e-19","1.65394439671043e-63","5.67620154598818e-21"]
["P-hsa04213-62","Longevity regulating pathway - multiple species: CAT*","DOWN","7.92168477520539e-28","6.57551243151448e-19","3.68967678866778e-51"]
["P-hsa05211-4","Renal cell carcinoma: SLC2A1","UP","3.1103903118001e-18","2.29022283102095e-20","2.76424632249594e-36"]
["P-hsa04261-37","Adrenergic signaling in cardiomyocytes: CREB3","DOWN","2.00082383730698e-51","1.55650247168267e-19","5.8729488453618e-18"]
["P-hsa04972-42","Pancreatic secretion: CFTR","DOWN","2.21548226170674e-55","4.45319381286537e-30","1.21721961434554e-17"]
["P-hsa05205-284","Proteoglycans in cancer: PRKCA*","DOWN","2.21538026791398e-27","2.96056542284146e-23","3.05439397357072e-17"]
["P-hsa04022-49","cGMP-PKG signaling pathway: ATP1B4","DOWN","3.71560278300447e-17","2.47569547251046e-25","1.86464542351042e-36"]
["P-hsa04921-46","Oxytocin signaling pathway: 3,5-Cyclic GMP*","DOWN","1.33590972341908e-77","4.20737244035006e-17","1.82786578103981e-68"]
["P-hsa04024-114","cAMP signaling pathway: HHIP","DOWN","7.25976957919018e-17","2.2816030436601e-24","1.07923887279854e-38"]
["P-hsa04916-15","Melanogenesis: MITF*","DOWN","6.68742486658485e-24","7.3696675211416e-17","3.70615292630273e-37"]
["P-hsa04919-26","Thyroid hormone signaling pathway: THRB","DOWN","9.43772399672561e-35","6.72364125249458e-54","1.15662115478881e-16"]
["P-hsa05215-39","Prostate cancer: RB1","UP","5.31514328629761e-23","9.36937481697909e-23","1.45415460380897e-16"]
["P-hsa05211-42","Renal cell carcinoma: SLC2A1*","UP","3.17411535460098e-16","3.47264750695057e-39","2.06449299212164e-28"]
["P-hsa05110-17","Vibrio cholerae infection: Cl-*","DOWN","6.0257327615537e-19","4.13472712383868e-16","1.10843423923399e-19"]
["P-hsa04919-100","Thyroid hormone signaling pathway: CTNNB1*","DOWN","1.76599276466428e-37","1.21053730930398e-29","6.14186214915605e-16"]
["P-hsa05218-21","Melanoma: RB1","UP","5.9945015938658e-21","1.06073317383202e-22","1.18738684873598e-15"]
["P-hsa05220-40","Chronic myeloid leukemia: RB1","UP","5.9945015938658e-21","1.06073317383202e-22","1.18738684873598e-15"]
["P-hsa04923-26 27","Regulation of lipolysis in adipocytes: PNPLA2 ABHD5","DOWN","2.12170438000202e-15","4.28148367492799e-50","4.83981574643405e-27"]
["P-hsa05212-34","Pancreatic cancer: E2F1","UP","5.98439519505177e-25","1.63256969540913e-116","2.5917778346628e-15"]
["P-hsa05223-28","Non-small cell lung cancer: RB1","UP","1.8677187398491e-24","1.60518118419386e-71","2.9722762462465e-15"]
["P-hsa05321-152","Inflammatory bowel disease (IBD): FOXP3*","UP","1.50715955138839e-36","1.23928781102084e-16","3.4663848324966e-15"]
["P-hsa05222-44","Small cell lung cancer: RB1","UP","2.43790866118875e-18","1.23230176559088e-18","5.56653851387624e-15"]
["P-hsa04923-66","Regulation of lipolysis in adipocytes: LIPE","DOWN","1.03322122415698e-91","1.02540694204732e-14","4.20120004343161e-60"]
["P-hsa04919-43","Thyroid hormone signaling pathway: TBC1D4","DOWN","1.43518964063695e-14","5.60392952893967e-54","1.95554266376724e-27"]
["P-hsa04012-21","ErbB signaling pathway: GSK3B","UP","1.65910269273878e-14","1.92668941439622e-67","2.04240076729863e-30"]
["P-hsa04623-9","Cytosolic DNA-sensing pathway: IKBKE","UP","2.24901783671931e-14","6.49268866127332e-31","2.48410603816876e-19"]
["P-hsa04610-57","Complement and coagulation cascades: PLAUR","UP","2.74167368174855e-22","2.32069219463641e-14","6.43090085547636e-15"]
["P-hsa04390-88","Hippo signaling pathway: ID1","DOWN","3.22886733378323e-22","3.31771417426069e-19","4.55253784260166e-14"]
["P-hsa05214-35","Glioma: E2F1","UP","2.91883954664127e-18","3.21413976062871e-84","5.65425743025377e-14"]
["P-hsa04520-44 47","Adherens junction: ACTB TJP1","DOWN","9.70945657114041e-14","9.34074027605372e-17","7.76423991350719e-28"]
["P-hsa04310-33","Wnt signaling pathway: CCND1","UP","6.4622912382481e-23","9.75800406478754e-14","4.4713199235158e-21"]
["P-hsa04024-113","cAMP signaling pathway: PTCH1","DOWN","1.55061938128703e-13","6.41685774876216e-22","9.49593137072951e-16"]
["P-hsa04916-6","Melanogenesis: DCT","DOWN","3.99483181068279e-79","1.86906236847065e-29","1.90511069795755e-13"]
["P-hsa04020-42","Calcium signaling pathway: MYLK4","DOWN","3.3588002687049e-54","2.30105996283248e-13","5.17953707486919e-29"]
["P-hsa04012-8","ErbB signaling pathway: STAT5A","DOWN","2.46205110904063e-13","7.80186983326779e-80","2.46732531371176e-38"]
["P-hsa05162-23","Measles: IRF3","UP","6.16138341369612e-18","2.77639965776621e-14","2.96442474403166e-13"]
["P-hsa04152-49","AMPK signaling pathway: GYS1","UP","1.1033303587412e-18","7.14751493483152e-30","3.45481506001285e-13"]
["P-hsa03320-8","PPAR signaling pathway: GK","DOWN","8.25382562864518e-19","3.5575751099343e-13","4.8034508104569e-24"]
["P-hsa03320-30","PPAR signaling pathway: LPL","DOWN","7.13901151236359e-79","5.37699165578987e-13","8.49592113342703e-39"]
["P-hsa04725-18","Cholinergic synapse: ITPR1","DOWN","5.40525194210198e-13","1.72396636090067e-16","1.68459622776048e-44"]
["P-hsa04012-31","ErbB signaling pathway: BAD","UP","7.60706902624994e-13","6.58273937943548e-52","8.69287655684484e-25"]
["P-hsa04550-34","Signaling pathways regulating pluripotency of stem cells: MAPK1*","DOWN","5.17571492852683e-42","1.20383696416076e-12","1.06529967160263e-43"]
["P-hsa04971-55","Gastric acid secretion: MYLK4","DOWN","1.75522640505406e-30","1.44078879808918e-12","1.64896519372951e-17"]
["P-hsa03320-37","PPAR signaling pathway: HMGCS2","DOWN","1.35818058313031e-15","1.01915839984148e-33","1.50817561506451e-12"]
["P-hsa04922-59","Glucagon signaling pathway: CPT1C","DOWN","1.4191951238749e-18","2.46014190331838e-21","1.72454656824833e-12"]
["P-hsa04310-36","Wnt signaling pathway: MYC","UP","4.00465782232369e-12","3.18911275041449e-13","7.4254066642376e-18"]
["P-hsa04550-36","Signaling pathways regulating pluripotency of stem cells: AKT3*","DOWN","2.48218627966162e-56","4.58127784659784e-12","3.60468935474316e-37"]
["P-hsa04012-25","ErbB signaling pathway: CDKN1B","UP","5.027425737679e-12","9.50851695198665e-70","5.11134479506314e-30"]
["P-hsa04211-42","Longevity regulating pathway - mammal: PPARGC1A","DOWN","4.19228272890358e-29","2.6181668065003e-30","7.82405450342677e-12"]
["P-hsa05014-49","Amyotrophic lateral sclerosis (ALS): H2O","DOWN","1.53061432996584e-22","1.30222231180713e-11","1.43559338124788e-20"]
["P-hsa04520-44 49","Adherens junction: ACTB VCL","DOWN","1.36517177900368e-17","1.72337424083851e-24","1.47823191252813e-11"]
["P-hsa04961-12","Endocrine and other factor-regulated calcium reabsorption: SLC8A1","DOWN","1.53818615324262e-11","4.82881015803636e-22","1.24217876483629e-30"]
["P-hsa04922-50","Glucagon signaling pathway: PCK1","DOWN","3.95757599903823e-25","3.99623985843487e-38","1.65373610134853e-11"]
["P-hsa05161-100","Hepatitis B: MMP9*","UP","3.11608077895708e-26","1.01549316883717e-17","1.98876281838736e-11"]
["P-hsa04931-87","Insulin resistance: D-Glucose*","DOWN","4.15216916602165e-51","8.62950089266963e-54","2.72098432292099e-11"]
["P-hsa04724-66","Glutamatergic synapse: PLA2G4B","DOWN","1.71588580310194e-16","7.63997348828558e-65","2.88072542677374e-11"]
["P-hsa04012-22","ErbB signaling pathway: EIF4EBP1","UP","2.97754631344368e-11","3.12074982145288e-71","2.56075193729351e-22"]
["P-hsa04925-18","Aldosterone synthesis and secretion: PDE2A","DOWN","2.2461606688438e-99","3.75362846923596e-11","2.19201179494973e-71"]
["P-hsa04919-40","Thyroid hormone signaling pathway: RCAN2","DOWN","4.57083841631321e-25","5.92467410559073e-11","7.25388881462763e-13"]
["P-hsa05012-71","Parkinson's disease: PRKACA*","DOWN","7.15939138286369e-43","3.03618605387423e-20","7.0626986657167e-11"]
["P-hsa05217-19","Basal cell carcinoma: HHIP","DOWN","8.25382562864518e-19","7.73131037832995e-11","1.39107056867417e-35"]
["P-hsa05221-35","Acute myeloid leukemia: EIF4EBP1","UP","9.39977010326935e-15","4.40076599202196e-43","7.90470675069804e-11"]
["P-hsa04923-52 53","Regulation of lipolysis in adipocytes: PNPLA2 ABHD5*","DOWN","1.62717053566924e-11","8.90759177669807e-11","4.76410533972702e-17"]
["P-hsa05016-52","Huntington's disease: CASP3","UP","1.46478852880817e-10","6.24674577311902e-25","4.44107159699336e-20"]
["P-hsa05160-7","Hepatitis C: IRF3","UP","4.4451404723848e-17","5.48377344293804e-22","1.56936029639185e-10"]
["P-hsa04530-11 13","Tight junction: TJP1 EPB41","DOWN","2.60914712560521e-36","2.20219944185492e-10","2.24061745340018e-28"]
["P-hsa04014-65","Ras signaling pathway: MLLT4*","DOWN","2.86260042675881e-11","2.38349272328716e-10","9.60371030977712e-29"]
["P-hsa05034-61","Alcoholism: CRH","DOWN","2.96636619939529e-10","1.2489464253166e-31","1.94791988008141e-20"]
["P-hsa05162-13","Measles: IRF7","UP","9.93769299778844e-29","8.07758797347739e-29","3.63902053677789e-10"]
["P-hsa04520-1 13","Adherens junction: SMAD4 SMAD2","DOWN","3.7679268300346e-66","3.96375801851301e-10","1.16171580911435e-50"]
["P-hsa04922-51","Glucagon signaling pathway: G6PC","DOWN","8.50583381822298e-17","8.66003593393127e-39","4.54345373792256e-10"]
["P-hsa03320-7","PPAR signaling pathway: AQP7","DOWN","2.17954315641444e-83","3.42784102003367e-13","6.21360270305873e-10"]
["P-hsa04630-35","Jak-STAT signaling pathway: MTOR","DOWN","8.07875107577224e-56","7.296990396234e-10","3.79753661484355e-19"]
["P-hsa04014-30","Ras signaling pathway: D-myo-Inositol 1,4,5-trisphosphate","DOWN","1.27131352795503e-11","8.10913610032753e-10","5.99174023120621e-30"]
["P-hsa05210-9 11","Colorectal cancer: SMAD2 SMAD4","DOWN","4.12118200821932e-16","3.42322398006439e-10","5.16942969216264e-10"]
["P-hsa05152-98","Tuberculosis: IL23A","UP","8.98261923004376e-10","4.93563064914156e-16","5.14607392724111e-12"]
["P-hsa03320-27","PPAR signaling pathway: CPT1C","DOWN","1.26137358509272e-09","6.49795994881406e-13","1.48020694857771e-13"]
["P-hsa04530-20 22","Tight junction: ACTB MYL12B","DOWN","1.38106935732818e-09","9.15707415245956e-20","5.11134479506314e-30"]
["P-hsa04152-24","AMPK signaling pathway: SIRT1","DOWN","2.46750189809248e-38","1.98843495735223e-09","3.00402316488828e-13"]
["P-hsa04340-15","Hedgehog signaling pathway: HHIP","DOWN","1.99844956227115e-09","1.4176357919401e-24","5.3679437670514e-21"]
["P-hsa05200-192","Pathways in cancer: PTGS2","DOWN","2.15626598011279e-27","7.67143442589676e-12","2.01140139228295e-09"]
["P-hsa04152-38","AMPK signaling pathway: PFKL","UP","1.63982481906076e-09","1.39227044464787e-23","4.64860060897982e-10"]
["P-hsa04919-29","Thyroid hormone signaling pathway: HIF1A","DOWN","1.99785200462508e-18","1.15822137879707e-68","2.46391698279779e-09"]
["P-hsa04530-11 20 16","Tight junction: TJP1 ACTB CTTN","DOWN","3.96031016033066e-13","2.63062459350399e-09","2.289895800812e-18"]
["P-hsa04911-25","Insulin secretion: PRKCA","DOWN","2.71427751653914e-09","2.9524773630602e-15","2.97379758976808e-17"]
["P-hsa05200-227","Pathways in cancer: FOXO1","DOWN","1.5870846161065e-49","4.83722281454806e-13","3.0457985885618e-09"]
["P-hsa04310-22","Wnt signaling pathway: ROCK2","DOWN","2.85443001283373e-20","3.78677944526305e-09","2.5116766228496e-17"]
["P-hsa04921-41","Oxytocin signaling pathway: PTGS2","DOWN","3.23747936672049e-38","6.41719983414119e-11","3.7377606210486e-09"]
["P-hsa04630-1","Jak-STAT signaling pathway: MYC","UP","2.43859157106776e-32","3.92206320802433e-09","2.51637488548039e-37"]
["P-hsa04022-71","cGMP-PKG signaling pathway: PPIF","UP","4.00665904014524e-09","7.06501805588881e-12","1.46375406273708e-49"]
["P-hsa05032-25","Morphine addiction: 3,5-Cyclic AMP*","DOWN","1.85590081496844e-10","1.85305026251905e-16","5.06984321648557e-09"]
["P-hsa04151-26","PI3K-Akt signaling pathway: RBL2","DOWN","7.30838476229933e-27","2.35371145555509e-40","5.39166942271731e-09"]
["P-hsa04961-13","Endocrine and other factor-regulated calcium reabsorption: ATP2B1","DOWN","5.70038248231787e-09","6.88117274718773e-12","2.18602592502182e-10"]
["P-hsa04530-11 43","Tight junction: TJP1 ACTN4","DOWN","1.70652104416681e-23","6.57454404482757e-09","2.06199809493355e-38"]
["P-hsa04360-11","Axon guidance: NFATC2","DOWN","7.32319275276351e-09","1.07964517449918e-09","1.6869577439948e-36"]
["P-hsa04211-57","Longevity regulating pathway - mammal: ATG5","DOWN","9.23020608968937e-09","2.59753158033452e-14","1.05852728775558e-13"]
["P-hsa04012-24","ErbB signaling pathway: CDKN1A","UP","9.54862324723272e-09","3.19045231011789e-68","1.03188280579849e-23"]
["P-hsa04610-11","Complement and coagulation cascades: F2R","UP","1.42562467189225e-24","1.00999788947229e-52","1.00949245735821e-08"]
["P-hsa04630-28","Jak-STAT signaling pathway: CCND1","UP","1.65189106882544e-46","1.54040429872069e-08","4.83801082602255e-45"]
["P-hsa04931-61","Insulin resistance: ACACB","DOWN","5.84913289155441e-73","1.62601298620024e-08","2.37574225792244e-32"]
["P-hsa04020-22","Calcium signaling pathway: 3,5-Cyclic AMP","DOWN","7.08833167170882e-09","2.03272125673381e-08","4.18703403758965e-31"]
["P-hsa04151-36","PI3K-Akt signaling pathway: PCK1","DOWN","1.89823958627598e-28","3.4788369319959e-58","3.22534127876049e-08"]
["P-hsa04022-51","cGMP-PKG signaling pathway: GTF2I","DOWN","1.42669765106441e-19","4.0250430523475e-08","2.2200052407815e-39"]
["P-hsa05200-146 147","Pathways in cancer: RARB RXRA","DOWN","4.96517182722878e-21","3.49582853896812e-14","4.54081232622903e-08"]
["P-hsa05222-14 15","Small cell lung cancer: RXRA RARB","DOWN","4.96517182722878e-21","3.49582853896812e-14","4.54081232622903e-08"]
["P-hsa05223-29 34","Non-small cell lung cancer: RARB RXRA","DOWN","4.96517182722878e-21","3.49582853896812e-14","4.54081232622903e-08"]
["P-hsa05031-97","Amphetamine addiction: ARC","DOWN","3.04304259701305e-09","7.29587063215811e-20","4.91251857026873e-08"]
["P-hsa04530-13 45 20","Tight junction: EPB41 TJP2 ACTB","DOWN","5.83488112600603e-08","3.67256204908838e-38","1.92791530750322e-29"]
["P-hsa04360-145","Axon guidance: ABLIM3","DOWN","3.0278270788968e-12","6.88250403558566e-08","2.64422127022299e-45"]
["P-hsa04110-48","Cell cycle: RB1*","UP","6.22033210101638e-11","2.68636460834658e-125","7.42191106204326e-08"]
["P-hsa04380-38","Osteoclast differentiation: FOS","DOWN","9.87224146255648e-11","7.59307823671014e-08","6.24453990126788e-23"]
["P-hsa04919-102","Thyroid hormone signaling pathway: BMP4","DOWN","1.05377682109375e-15","7.92700034903926e-08","1.66453052292614e-09"]
["P-hsa04972-18","Pancreatic secretion: PRKCA","DOWN","8.70824745114713e-08","2.09139441154235e-17","7.59876588563037e-16"]
["P-hsa04622-45","RIG-I-like receptor signaling pathway: MAPK14","UP","1.49477616159142e-32","9.3247216020425e-08","7.52276293898858e-11"]
["P-hsa05031-8","Amphetamine addiction: DRD1","DOWN","5.92278143078323e-11","1.44389700534025e-14","9.47604995044779e-08"]
["P-hsa04010-79","MAPK signaling pathway: HSPB1","UP","9.27573635760848e-08","6.76450560944193e-16","6.73007963516198e-09"]
["P-hsa04931-149","Insulin resistance: ACACB*","DOWN","6.51758505260371e-63","1.09898136839334e-07","4.13261714449678e-27"]
["P-hsa04919-104","Thyroid hormone signaling pathway: MYC","DOWN","1.13196420102692e-49","1.19550839159635e-07","9.57465226825832e-17"]
["P-hsa05020-49","Prion diseases: BAX","UP","8.20666979620514e-21","1.23134697341987e-07","2.06987920558922e-09"]
["P-hsa04722-38","Neurotrophin signaling pathway: ATF4","DOWN","1.6633125011244e-30","1.2748257704478e-07","2.37773646840877e-44"]
["P-hsa04961-5","Endocrine and other factor-regulated calcium reabsorption: TRPV5","DOWN","1.25478903345213e-10","3.82987927067095e-119","1.44705409138088e-07"]
["P-hsa05221-21","Acute myeloid leukemia: PIM1","DOWN","1.9400021673019e-18","6.37660382628246e-16","1.90920067132133e-07"]
["P-hsa05140-62","Leishmaniasis: Prostaglandin E2","DOWN","9.95592044417646e-28","5.60141237230701e-10","1.98433065751298e-07"]
["P-hsa04530-11 62","Tight junction: TJP1 SHROOM1","DOWN","2.01423944851861e-07","4.3834437065092e-24","3.08575630471182e-33"]
["P-hsa05020-24","Prion diseases: PRNP*","DOWN","1.22006715956683e-37","2.11824699942379e-07","5.27274962839679e-15"]
["P-hsa05020-26","Prion diseases: PRNP**","DOWN","1.22006715956683e-37","2.11824699942379e-07","5.27274962839679e-15"]
["P-hsa05020-25 8","Prion diseases: PRNP PRNP*","DOWN","1.22006715956683e-37","2.11824699942379e-07","5.27274962839679e-15"]
["P-hsa05020-10 34","Prion diseases: PRNP PRNP***","DOWN","1.22006715956683e-37","2.11824699942379e-07","5.27274962839679e-15"]
["P-hsa04390-89","Hippo signaling pathway: ID2","DOWN","2.47178380080042e-07","4.7934920036331e-08","4.92964322798884e-14"]
["P-hsa04014-55","Ras signaling pathway: MLLT4","DOWN","3.41970722659517e-07","6.36103734091775e-12","3.74468721338046e-10"]
["P-hsa04810-21 82","Regulation of actin cytoskeleton: CFL1 ACTB","UP","3.26127431455023e-10","1.67161581655604e-24","3.80017447951521e-07"]
["P-hsa05205-431","Proteoglycans in cancer: CDKN1A*","DOWN","2.18194206788242e-43","3.86462641427068e-07","4.92085207485132e-12"]
["P-hsa05219-19","Bladder cancer: TP53","DOWN","5.73964465839624e-17","1.35542899936867e-133","4.64761405975866e-07"]
["P-hsa04670-14","Leukocyte transendothelial migration: SIPA1","UP","4.93751003351364e-07","1.85152933042583e-31","1.83880365904477e-11"]
["P-hsa05152-13","Tuberculosis: LAMP1","DOWN","5.18743421309029e-07","3.60913610588798e-14","1.99835570137667e-23"]
["P-hsa04914-23","Progesterone-mediated oocyte maturation: PRKACA","UP","4.6314288935677e-23","5.68680778498123e-07","1.3288554835709e-11"]
["P-hsa05166-132 136","HTLV-I infection: CREBBP TP53","UP","5.87886374171867e-07","1.00533349166508e-17","8.60990690888223e-29"]
["P-hsa04750-44","Inflammatory mediator regulation of TRP channels: TRPA1","UP","1.21864474654103e-12","6.64826249746421e-52","7.67464928842228e-07"]
["P-hsa04750-63","Inflammatory mediator regulation of TRP channels: TRPA1*","UP","1.21864474654103e-12","6.64826249746421e-52","7.67464928842228e-07"]
["P-hsa05200-188","Pathways in cancer: KLK3","DOWN","2.2845586231221e-13","2.18741059260536e-09","8.50165150242434e-07"]
["P-hsa05215-12","Prostate cancer: KLK3","DOWN","2.14821858199638e-13","2.05219547333096e-09","8.5695815715825e-07"]
["P-hsa04014-42","Ras signaling pathway: PLA2G4B","DOWN","8.78268536154915e-07","1.19219307202473e-09","2.01514669673004e-11"]
["P-hsa04151-25","PI3K-Akt signaling pathway: CDKN1B","DOWN","1.9426369743178e-11","1.43084752250217e-29","9.21853510394479e-07"]
["P-hsa05150-1 2 3","Staphylococcus aureus infection: CFD C3 CFB","UP","1.196473949592e-07","8.93815462859269e-16","8.40616099541304e-07"]
["P-hsa04530-11 36 14","Tight junction: TJP1 CTNNB1 CTNNA1","DOWN","1.59735636360641e-24","1.06801588956563e-06","1.1784142662909e-22"]
["P-hsa05132-86","Salmonella infection: MYH9","DOWN","3.46112897186281e-12","1.38004075406847e-06","1.46870679000323e-08"]
["P-hsa04914-30","Progesterone-mediated oocyte maturation: CDK1*","UP","1.76477665389014e-70","1.50095091997476e-06","3.76231526414591e-30"]
["P-hsa04976-95 96","Bile secretion: SLC51A SLC51B","DOWN","9.51492480852145e-14","1.5344486985664e-06","3.20115093529598e-12"]
["P-hsa04622-21 22 23","RIG-I-like receptor signaling pathway: CHUK IKBKB IKBKG","UP","1.35818058313031e-15","1.66633222265007e-18","1.61955378462931e-06"]
["P-hsa04210-60","Apoptosis: BBC3","UP","4.62108692858411e-09","1.10136507728476e-60","1.71652944951974e-06"]
["P-hsa04960-4","Aldosterone-regulated sodium reabsorption: ATP1B4","DOWN","8.53448688528778e-42","5.01953651556079e-89","1.87104050900325e-06"]
["P-hsa04730-30","Long-term depression: L-Glutamate*","DOWN","1.87562290254746e-06","1.27446691530833e-44","1.25395501884094e-43"]
["P-hsa04933-23","AGE-RAGE signaling pathway in diabetic complications: F3","DOWN","1.6942313441737e-34","1.88624984366785e-06","9.65774884399358e-34"]
["P-hsa04919-103","Thyroid hormone signaling pathway: CCND1","DOWN","2.02247775160496e-06","3.86131403185154e-08","5.27253943955391e-18"]
["P-hsa04340-17","Hedgehog signaling pathway: SMO","UP","5.35250330181361e-19","2.20906591034282e-06","1.74578406509764e-09"]
["P-hsa04360-40 139","Axon guidance: UNC5D DCC","DOWN","2.30518693871493e-06","5.30998716850111e-09","9.99021392985535e-43"]
["P-hsa05231-39","Choline metabolism in cancer: EIF4EBP1","UP","1.14079180673344e-07","2.64367250233857e-50","2.46802017543562e-06"]
["P-hsa05133-59","Pertussis: C3","UP","7.26688665852433e-20","1.07640910279659e-34","3.09573920594568e-06"]
["P-hsa04919-21 53","Thyroid hormone signaling pathway: THRA Triiodothyronine","DOWN","8.12383151315469e-14","7.47120661756543e-14","3.09573920594568e-06"]
["P-hsa05168-122","Herpes simplex infection: CASP3","UP","5.21789540597328e-09","1.66136601172252e-18","4.21992170266997e-06"]
["P-hsa04022-48","cGMP-PKG signaling pathway: SLC8A2","DOWN","3.62989401666185e-18","4.380789787196e-06","3.80100227475523e-56"]
["P-hsa04261-39","Adrenergic signaling in cardiomyocytes: SCN1B","DOWN","7.68613144286853e-64","5.07776357124903e-06","7.85875174743876e-89"]
["P-hsa04022-43","cGMP-PKG signaling pathway: MAPK1","DOWN","8.30031462398159e-18","5.65476716193855e-06","3.23159594229416e-55"]
["P-hsa03320-36","PPAR signaling pathway: SLC27A4","DOWN","1.85101878199233e-60","2.25188793425138e-18","6.29789361373001e-06"]
["P-hsa04931-13","Insulin resistance: AKT2","DOWN","1.11799061442592e-50","1.27598037134988e-45","6.54012607822135e-06"]
["P-hsa05161-213","Hepatitis B: E2F1","UP","5.85097799885481e-17","6.86033763131132e-06","2.68770533389337e-15"]
["P-hsa04151-37","PI3K-Akt signaling pathway: G6PC","DOWN","5.49944732486283e-08","1.37111956085521e-68","7.42190724146787e-06"]
["P-hsa05133-60","Pertussis: C5","UP","1.14168302836815e-20","1.14837292174884e-08","7.89121520794435e-06"]
["P-hsa05221-13","Acute myeloid leukemia: NFKB1","DOWN","4.96558833236506e-08","7.01243313063113e-17","8.41756124487013e-06"]
["P-hsa04071-11","Sphingolipid signaling pathway: PRKCA","DOWN","2.84662001982423e-08","8.20603297039672e-06","4.14756929617648e-07"]
["P-hsa05214-52","Glioma: E2F1*","UP","3.93881867101184e-15","1.01781715194626e-05","2.66930980431325e-14"]
["P-hsa04012-23","ErbB signaling pathway: RPS6KB1","DOWN","1.1481193887492e-05","3.95271642845585e-77","4.16692569434943e-16"]
["P-hsa05205-30","Proteoglycans in cancer: FLNA","DOWN","4.04411756038372e-20","1.17980930726032e-05","1.89452299689655e-10"]
["P-hsa04925-3","Aldosterone synthesis and secretion: ITPR1","DOWN","3.77554596494976e-13","1.25365821725567e-05","2.26979170389091e-42"]
["P-hsa04210-114","Apoptosis: HRK","DOWN","4.59772901121279e-14","4.64637121232829e-07","1.22918940212947e-05"]
["P-hsa04024-112","cAMP signaling pathway: GLI1","DOWN","1.87484795245973e-06","1.45386969560636e-05","4.22423388050994e-08"]
["P-hsa04810-32","Regulation of actin cytoskeleton: PXN","UP","8.57737434461487e-06","7.89220922892533e-06","4.38693779236441e-11"]
["P-hsa04932-58","Non-alcoholic fatty liver disease (NAFLD): BAX","UP","3.93244256418691e-18","1.04915970660756e-08","1.68731405622877e-05"]
["P-hsa04015-96","Rap1 signaling pathway: PLCE1","DOWN","1.27024668846643e-10","1.75352795464504e-05","4.61400307542329e-33"]
["P-hsa05164-41 42","Influenza A: STAT1 IRF9","UP","4.87374516253995e-08","4.00855861226865e-24","1.9386780268138e-05"]
["P-hsa04010-67","MAPK signaling pathway: ELK1","UP","2.10616299651271e-05","3.40823540427913e-55","1.29389434045022e-12"]
["P-hsa04960-27","Aldosterone-regulated sodium reabsorption: KCNJ1","DOWN","2.86674885846528e-22","9.23261936564911e-156","2.23766850626894e-05"]
["P-hsa05205-45 46","Proteoglycans in cancer: PAK1 FLNA","UP","2.229601489447e-08","1.97179078743652e-05","3.02893315691776e-06"]
["P-hsa03320-63","PPAR signaling pathway: DBI","DOWN","6.22684899896568e-25","6.74059217649879e-32","2.34450779657669e-05"]
["P-hsa04530-20 31","Tight junction: ACTB MLLT4","DOWN","2.44776253623545e-05","1.89243140212921e-18","3.8037006242251e-16"]
["P-hsa04014-64","Ras signaling pathway: PIK3R5*","DOWN","1.37261838549433e-15","2.45228013860313e-05","4.12268384359812e-42"]
["P-hsa05166-136 139","HTLV-I infection: TP53 TBPL2","UP","5.43813654661846e-06","2.0127284986651e-05","3.09916970582041e-19"]
["P-hsa05211-46","Renal cell carcinoma: AKT3","DOWN","7.17460960463272e-47","2.75437057649784e-05","2.11399690826949e-22"]
["P-hsa04152-68","AMPK signaling pathway: PPARGC1A**","DOWN","1.73884636804757e-07","2.09519797531329e-16","2.76428241407492e-05"]
["P-hsa04933-21","AGE-RAGE signaling pathway in diabetic complications: SMAD4","DOWN","8.62061920030134e-11","3.19525044231674e-05","1.2707737977954e-28"]
["P-hsa04350-32","TGF-beta signaling pathway: RPS6KB1","UP","5.47437584367117e-09","3.12044370704483e-05","1.92069556525147e-06"]
["P-hsa04722-46","Neurotrophin signaling pathway: ATF4*","DOWN","3.46388818882628e-33","3.33337222025337e-05","6.50831691891994e-35"]
["P-hsa04914-39","Progesterone-mediated oocyte maturation: PIK3R5","DOWN","3.46254159835837e-05","3.16224588659143e-18","4.46285571041568e-35"]
["P-hsa04933-63","AGE-RAGE signaling pathway in diabetic complications: SELE","DOWN","1.40432411459682e-05","2.15823092655067e-05","3.67904388129608e-40"]
["P-hsa05168-123","Herpes simplex infection: CYCS","UP","8.99739758808024e-09","2.67183421376679e-09","3.74976065154253e-05"]
["P-hsa04914-29","Progesterone-mediated oocyte maturation: CDK2","UP","3.5086271040933e-16","5.1083667307433e-10","3.97116962088451e-05"]
["P-hsa04620-77","Toll-like receptor signaling pathway: CXCL9","UP","7.05997571823407e-10","6.23646467924101e-20","4.37190382070375e-05"]
["P-hsa05221-26","Acute myeloid leukemia: BAD","UP","2.766290062241e-16","1.28170842832692e-14","4.42221456600545e-05"]
["P-hsa04024-118","cAMP signaling pathway: MYL9","DOWN","4.53905685830501e-05","2.29098700162828e-16","3.55348814274378e-21"]
["P-hsa04810-26 80","Regulation of actin cytoskeleton: PFN3 ACTB","UP","4.96890572893632e-13","9.3524433368232e-20","5.07474246239739e-05"]
["P-hsa04666-20","Fc gamma R-mediated phagocytosis: PLA2G4B","DOWN","5.96383673467838e-05","8.07411176764662e-15","1.79995471302404e-30"]
["P-hsa03460-27","Fanconi anemia pathway: BRCA1","UP","2.41651156033042e-21","6.26086243434685e-05","9.27369823222234e-21"]
["P-hsa04010-78","MAPK signaling pathway: MAP3K4","DOWN","6.5862017852591e-05","1.02112931139406e-17","2.33247159363271e-31"]
["P-hsa04722-85","Neurotrophin signaling pathway: BAX","DOWN","3.03393691081575e-06","3.65186433654934e-07","6.30819774615734e-05"]
["P-hsa04530-6 11 45","Tight junction: CLDN24 TJP1 TJP2","DOWN","6.70341286038631e-05","3.19455046172822e-40","4.71995460661826e-35"]
["P-hsa04919-31","Thyroid hormone signaling pathway: ATP2A2","DOWN","2.80967627284371e-17","5.88097464708775e-25","6.76901489636524e-05"]
["P-hsa04261-3","Adrenergic signaling in cardiomyocytes: RYR2","DOWN","3.19648092593558e-29","8.51931931508821e-05","6.44740113794248e-54"]
["P-hsa04620-19","Toll-like receptor signaling pathway: CXCL10","UP","7.23174174337153e-10","4.2136338954476e-19","9.16086726990891e-05"]
["P-hsa05217-4","Basal cell carcinoma: PTCH1","DOWN","3.39260153680398e-38","9.91133547965489e-05","4.3469552997958e-13"]
["P-hsa05010-12","Alzheimer's disease: CASP3","UP","8.35322725691869e-15","0.000101717882062611","1.69441525535171e-08"]
["P-hsa03460-48","Fanconi anemia pathway: RAD51","UP","9.1851019815083e-11","4.20842687957111e-30","0.000135215180762628"]
["P-hsa04620-20","Toll-like receptor signaling pathway: IFNB1*","UP","3.82433366624632e-08","3.60116674919061e-05","0.000101402235192902"]
["P-hsa04919-32","Thyroid hormone signaling pathway: PLN","DOWN","4.48231726690215e-25","0.000140207794253401","1.3272394307971e-18"]
["P-hsa04530-30","Tight junction: AKT3","UP","0.000140479849497182","7.41505696805429e-59","1.17106403479458e-21"]
["P-hsa04310-14","Wnt signaling pathway: PRKCA","DOWN","3.58300400228645e-10","2.79806666860249e-08","0.000156545401073214"]
["P-hsa04380-20","Osteoclast differentiation: MAP2K1","DOWN","0.000189516006057774","2.334417308699e-13","4.35098801284666e-13"]
["P-hsa04810-82 83","Regulation of actin cytoskeleton: ACTB ARPC5","DOWN","3.85061384795769e-05","7.89290030374321e-05","8.73131716006984e-05"]
["P-hsa05205-270","Proteoglycans in cancer: MAPK1****","DOWN","1.89754825309877e-25","0.000221576057579551","1.46799041914363e-22"]
["P-hsa04660-43","T cell receptor signaling pathway: RHOA","DOWN","5.62271216248145e-12","0.000222030668617087","1.41236363621351e-48"]
["P-hsa04010-54","MAPK signaling pathway: NR4A1","DOWN","3.16720501733767e-31","0.000222348958144532","2.14459405434164e-25"]
["P-hsa05161-188","Hepatitis B: IFNB1","UP","4.68192477064286e-08","4.62340359414427e-05","0.000182978788125887"]
["P-hsa04022-65","cGMP-PKG signaling pathway: PDE2A","DOWN","3.52830459380464e-91","0.000235930625513907","4.60017537039432e-50"]
["P-hsa05160-66","Hepatitis C: GSK3B","UP","0.000190398053490872","7.4159823984206e-17","4.77869158944297e-05"]
["P-hsa04211-39","Longevity regulating pathway - mammal: TP53*","UP","3.11641139884745e-05","1.82985269125682e-07","0.000219082709385464"]
["P-hsa04152-89","AMPK signaling pathway: CFTR","DOWN","9.01940374918673e-11","0.000283125871375906","3.05995986687984e-09"]
["P-hsa04068-72","FoxO signaling pathway: SMAD2","DOWN","1.61636013048179e-15","0.000299999770091097","1.18989979173556e-14"]
["P-hsa04724-26","Glutamatergic synapse: PRKACA","DOWN","2.83359150653386e-11","2.30644332542903e-85","0.000301837989459039"]
["P-hsa05168-91 92","Herpes simplex infection: STAT1 IRF9","UP","2.57900834579612e-06","2.60707699748984e-21","0.000321170235413861"]
["P-hsa05222-36","Small cell lung cancer: PTGS2","DOWN","2.87841476311038e-19","0.000200527802489652","0.000154913237839286"]
["P-hsa04066-56","HIF-1 signaling pathway: TEK","DOWN","1.22159075022629e-53","0.000389327473757036","2.38046110799441e-92"]
["P-hsa05200-199","Pathways in cancer: BCL2L1**","DOWN","3.10318593782467e-13","1.76001889086303e-06","0.000413303642756954"]
["P-hsa05220-3","Chronic myeloid leukemia: BCL2L1","DOWN","3.10318593782467e-13","1.76001889086303e-06","0.000413303642756954"]
["P-hsa04725-54","Cholinergic synapse: CHRM1*","DOWN","3.6664649672609e-07","0.000425959192414311","1.70175174977303e-26"]
["P-hsa04211-62","Longevity regulating pathway - mammal: EHMT2","UP","2.74041370412986e-28","0.000427485169206734","1.02131752838828e-11"]
["P-hsa05220-22","Chronic myeloid leukemia: CDKN1B","UP","5.3544686018286e-05","6.44237257748582e-09","0.00039050868916421"]
["P-hsa04920-12","Adipocytokine signaling pathway: Diacylglycerol","DOWN","0.000446060964735086","9.21844387293226e-38","5.42052026838766e-30"]
["P-hsa04742-49","Taste transduction: HTR1A","UP","0.000225447257885429","1.0418340231098e-06","0.00022999732569302"]
["P-hsa05205-195","Proteoglycans in cancer: CDKN1A","DOWN","0.000492321543978198","1.45616539588845e-19","9.90506959260511e-14"]
["P-hsa05145-67","Toxoplasmosis: BAD","UP","0.00052115833004295","2.11824699942379e-07","1.00462976946784e-09"]
["P-hsa05220-4","Chronic myeloid leukemia: PTPN11","DOWN","0.000569504992851877","1.32700790257417e-05","6.21258744099916e-13"]
["P-hsa04630-30","Jak-STAT signaling pathway: CDKN1A","UP","8.69112689173939e-46","0.000638023151757134","1.21086544610217e-41"]
["P-hsa04390-96","Hippo signaling pathway: FGF1","DOWN","1.9172218530493e-54","9.97125166166171e-11","0.000667699360647649"]
["P-hsa04724-68","Glutamatergic synapse: MAPK1","DOWN","1.78556345469123e-13","1.0465126516879e-19","0.00067058456163605"]
["P-hsa04152-57","AMPK signaling pathway: ACACA*","UP","4.65330553746517e-22","2.75935636318452e-05","0.000666354144111929"]
["P-hsa05110-14","Vibrio cholerae infection: Potassium cation*","DOWN","0.000498121084032268","7.61204576232801e-42","0.00020097928050403"]
["P-hsa05110-15","Vibrio cholerae infection: Sodium cation","DOWN","0.000498121084032268","7.61204576232801e-42","0.00020097928050403"]
["P-hsa05110-16","Vibrio cholerae infection: Cl-","DOWN","0.000498121084032268","7.61204576232801e-42","0.00020097928050403"]
["P-hsa05169-104","Epstein-Barr virus infection: IRF3","UP","1.81524257195108e-16","2.85934986819058e-32","0.000707872135642174"]
["P-hsa04360-122","Axon guidance: CFL1**","DOWN","0.000723406834186607","9.8654439812829e-151","1.83317618499214e-27"]
["P-hsa05219-21","Bladder cancer: RB1","UP","1.31019765427733e-08","5.71305295225067e-29","0.000775213201892347"]
["P-hsa04152-77","AMPK signaling pathway: CCND1","UP","1.87919717644349e-38","7.63818943271451e-59","0.00083890238742671"]
["P-hsa04623-8","Cytosolic DNA-sensing pathway: TBK1","UP","3.81768740132358e-07","8.17211379700732e-59","0.000885727097906355"]
["P-hsa04210-57","Apoptosis: BAK1","UP","0.000907560819472337","2.45863067462761e-07","2.88228194673509e-10"]
["P-hsa05030-37","Cocaine addiction: PRKACA","DOWN","0.000885241893033295","8.49784167032658e-12","2.97276364787919e-05"]
["P-hsa04950-5","Maturity onset diabetes of the young: GCK","DOWN","0.000473654834996552","2.20981080613973e-09","0.000481475385433886"]
["P-hsa05152-51","Tuberculosis: CASP3","UP","0.000282319549190403","2.5178985744234e-05","0.000651905790819867"]
["P-hsa04972-51","Pancreatic secretion: CLCA1","DOWN","8.84343436402385e-13","0.000963246410652511","5.68811061339568e-08"]
["P-hsa05142-53","Chagas disease (American trypanosomiasis): AKT3","DOWN","0.00107791983697494","7.6548270002032e-11","3.05443086903222e-11"]
["P-hsa04360-35","Axon guidance: ROCK1*","UP","2.2786375102506e-07","0.0011192998714597","1.27469621854496e-35"]
["P-hsa04520-44 52 45","Adherens junction: ACTB ACTN4 CTNNA1","DOWN","0.000117856952705953","0.000754484290844761","0.000272314202363841"]
["P-hsa05160-85","Hepatitis C: BAD","UP","0.000725365252696638","6.20918563534841e-12","0.000438002993612152"]
["P-hsa04310-32","Wnt signaling pathway: PPARD","UP","8.03122447828382e-21","0.00128798608965496","1.03841785658303e-30"]
["P-hsa05220-25","Chronic myeloid leukemia: BCL2L1*","DOWN","0.00126066709709341","8.71200372382406e-06","0.000106025439916792"]
["P-hsa04390-75","Hippo signaling pathway: NKD1","DOWN","0.00138963665356629","6.34874436157506e-54","8.39914838615978e-18"]
["P-hsa04921-57","Oxytocin signaling pathway: FOS","DOWN","7.30701885281933e-45","0.00154458474029062","6.65512904046154e-24"]
["P-hsa05205-150","Proteoglycans in cancer: PRKCA","DOWN","3.63074206833869e-17","8.17033700856762e-46","0.00159246201857001"]
["P-hsa04922-78","Glucagon signaling pathway: ACACA","DOWN","2.20483857800243e-17","3.2136445501196e-05","0.00159522514821477"]
["P-hsa04923-31","Regulation of lipolysis in adipocytes: PRKACA*","UP","1.62033299069999e-10","1.4173232605335e-25","0.00165655804575896"]
["P-hsa05211-48","Renal cell carcinoma: JUN","DOWN","1.05431133571101e-30","0.00166232693484089","1.68981725023895e-23"]
["P-hsa04931-29","Insulin resistance: CPT1B","UP","0.00172814844443982","2.74938619873589e-08","4.4713199235158e-21"]
["P-hsa05219-27","Bladder cancer: RPS6KA5","DOWN","0.000259107828608438","0.00158403739785648","3.51249712198012e-30"]
["P-hsa04211-38","Longevity regulating pathway - mammal: BAX","UP","7.48099158425759e-23","4.62021186189404e-22","0.00190570132363553"]
["P-hsa04210-56","Apoptosis: BAX","UP","1.33746659230093e-05","7.96076116359345e-52","0.0018973465868384"]
["P-hsa05014-5","Amyotrophic lateral sclerosis (ALS): TOMM40","UP","8.36081458161531e-17","1.35688291189427e-18","0.00203792297260137"]
["P-hsa05133-73","Pertussis: FOS","DOWN","7.32569022557162e-45","0.00204961688410074","1.27352629926801e-21"]
["P-hsa04924-31","Renin secretion: Angiotensin II","DOWN","5.37237994686954e-10","0.00215374372472016","5.59472152040514e-32"]
["P-hsa05014-54","Amyotrophic lateral sclerosis (ALS): PPP3CA","DOWN","4.23507082183725e-07","6.86789353672167e-05","0.00208563589125477"]
["P-hsa04730-20","Long-term depression: L-Glutamate","DOWN","0.00216409771045721","9.16482811748835e-45","2.67184892642179e-44"]
["P-hsa04620-18","Toll-like receptor signaling pathway: CXCL11","UP","7.7270913673879e-10","7.28497956930076e-20","0.00222120929646122"]
["P-hsa04933-52","AGE-RAGE signaling pathway in diabetic complications: FOXO1","DOWN","8.38047527265704e-38","0.00244275003662616","1.04942145410803e-42"]
["P-hsa05132-13","Salmonella infection: FOS","DOWN","6.95690222922395e-41","0.00249450929932174","1.40074165822959e-19"]
["P-hsa04014-33","Ras signaling pathway: BCL2L1","DOWN","0.0025423242656486","5.62833826466947e-07","3.47214198457749e-06"]
["P-hsa04022-9","cGMP-PKG signaling pathway: ITPR1","UP","1.43755030976457e-22","0.00257277570769817","1.27433376684928e-26"]
["P-hsa05152-129","Tuberculosis: IFNB1","UP","1.1585395557075e-05","2.28624270470155e-05","0.00259261292114067"]
["P-hsa04024-7","cAMP signaling pathway: TNNI3","UP","4.93160946053285e-09","0.002271959673002","0.000659325190800304"]
["P-hsa05221-41","Acute myeloid leukemia: MAPK1","DOWN","0.000753375212363085","5.31853392751768e-14","0.00218859730335928"]
["P-hsa05034-62","Alcoholism: NPY","DOWN","0.000265328787091703","8.31231027484111e-07","0.00268267019742554"]
["P-hsa04014-69","Ras signaling pathway: PLCE1*","DOWN","0.0029224809464686","0.000119786561624376","1.4807759081588e-54"]
["P-hsa04970-27","Salivary secretion: PRKCA","DOWN","1.82633438300337e-29","0.00306169091467681","2.36062101757278e-33"]
["P-hsa04530-1 5","Tight junction: IGSF5 IGSF5","DOWN","0.00306443162760578","5.88319830338336e-22","1.41954237479956e-37"]
["P-hsa04151-110","PI3K-Akt signaling pathway: BCL2**","UP","8.04140452509638e-13","5.35000688053052e-48","0.00310340114488268"]
["P-hsa05231-59","Choline metabolism in cancer: PLA2G4B","DOWN","0.00349355756619334","7.78125721845724e-38","3.42053223556395e-12"]
["P-hsa04010-58","MAPK signaling pathway: CDC25B","UP","0.00382445389868313","8.69145858693243e-22","8.52717893477267e-08"]
["P-hsa04750-39","Inflammatory mediator regulation of TRP channels: D-myo-Inositol 1,4,5-trisphosphate*","DOWN","9.81962654726901e-06","0.00039631680808814","0.0035018119370594"]
["P-hsa04380-16","Osteoclast differentiation: NFKB1","DOWN","0.00396178728699614","1.75117673611227e-05","3.45022031506645e-14"]
["P-hsa04022-39","cGMP-PKG signaling pathway: KCNJ8","DOWN","9.28458688740604e-37","0.00422598925278233","1.03262247345572e-95"]
["P-hsa05211-12","Renal cell carcinoma: EGLN2","UP","0.00423895465549795","4.17762118854827e-71","2.02242736120203e-05"]
["P-hsa03460-28","Fanconi anemia pathway: RAD51C","UP","0.00443878547769257","2.58036227643285e-20","9.50102455128035e-05"]
["P-hsa04724-36","Glutamatergic synapse: TRPC1","DOWN","4.45286323718873e-06","6.42974373976638e-62","0.00471932759994777"]
["P-hsa04152-94","AMPK signaling pathway: MLYCD","DOWN","5.19511120177567e-66","0.00474504693749765","2.91436007975882e-16"]
["P-hsa05142-36","Chagas disease (American trypanosomiasis): SMAD2","DOWN","8.99577349189012e-09","6.34729634316991e-08","0.00486089147056646"]
["P-hsa04330-19","Notch signaling pathway: DTX2","UP","9.95611793357965e-09","4.99158564033219e-07","0.00488568409151973"]
["P-hsa04152-44","AMPK signaling pathway: SLC2A4","DOWN","7.14733664146146e-83","0.00498148607921696","3.24443928245323e-05"]
["P-hsa04310-34","Wnt signaling pathway: FOSL1","UP","1.06654521817329e-10","0.00501971967958359","8.90446396808041e-10"]
["P-hsa04151-109","PI3K-Akt signaling pathway: RXRA","UP","2.44595388900869e-24","1.42131772567882e-38","0.00503277356052778"]
["P-hsa04530-5 11 31","Tight junction: IGSF5 TJP1 MLLT4","DOWN","2.66368868629693e-15","0.00518748684540998","9.44144775958888e-34"]
["P-hsa05162-93","Measles: TP53","UP","0.00530105989652335","5.88484309020453e-11","6.54960088112875e-07"]
["P-hsa05215-34","Prostate cancer: BAD","UP","0.00468732867257696","9.45548606199647e-12","0.000623913278968088"]
["P-hsa04072-3","Phospholipase D signaling pathway: MAPK1","DOWN","1.01129767183818e-17","0.00169110585842239","0.00385819039076289"]
["P-hsa04390-13","Hippo signaling pathway: BIRC5","UP","0.00557468122510386","6.70797240355776e-40","3.53322732420381e-12"]
["P-hsa04350-34","TGF-beta signaling pathway: ROCK1","UP","2.20866588978142e-06","0.000273995588949406","0.00538950188116961"]
["P-hsa04930-8","Type II diabetes mellitus: Pyruvate","UP","3.77767772289487e-25","5.41838719247219e-17","0.00574443799110474"]
["P-hsa05164-99","Influenza A: FDPS","DOWN","0.00517816140791139","2.92744743761842e-05","0.000617059693380908"]
["P-hsa04550-101","Signaling pathways regulating pluripotency of stem cells: ESRRB","DOWN","7.19564693150137e-14","1.73258966957963e-157","0.00595989034387584"]
["P-hsa04724-65","Glutamatergic synapse: GRM3","DOWN","0.00599982837388811","1.92683750016977e-09","6.75843646766933e-26"]
["P-hsa04340-33","Hedgehog signaling pathway: HHIP*","DOWN","4.01990341629973e-22","0.00634668256732682","2.65831015199611e-28"]
["P-hsa04360-33 134","Axon guidance: NCK1 PAK4","DOWN","8.49772586283623e-06","0.00637285153120952","6.28794284766603e-34"]
["P-hsa04270-17","Vascular smooth muscle contraction: ITPR1","DOWN","3.33074672027166e-16","0.00690865798956916","9.18448791431343e-26"]
["P-hsa04270-10 3 71","Vascular smooth muscle contraction: ACTA2 MYL9 MYH11","DOWN","2.24247117294271e-89","0.00692749780703421","5.28889114318079e-60"]
["P-hsa04010-129","MAPK signaling pathway: FOS","DOWN","7.56132068688825e-21","0.00696697288685176","6.64277191025284e-11"]
["P-hsa04020-64","Calcium signaling pathway: Sodium cation*","DOWN","0.00707634438561852","3.66069938671095e-08","1.82423158799763e-21"]
["P-hsa04020-12","Calcium signaling pathway: Sodium cation","DOWN","0.00707634438561852","3.66069938671095e-08","1.82423158799763e-21"]
["P-hsa04917-68","Prolactin signaling pathway: CCND1","DOWN","0.00716434249242439","1.5820522486459e-14","1.04314779647632e-10"]
["P-hsa04380-69","Osteoclast differentiation: NFKB2","DOWN","0.00286958225093181","0.00492841549742425","5.64338275787159e-18"]
["P-hsa04211-50","Longevity regulating pathway - mammal: PPARGC1A*","DOWN","1.81167915895641e-45","8.3495682290488e-08","0.0082833778404438"]
["P-hsa04064-134","NF-kappa B signaling pathway: CCL21","DOWN","3.12748081336252e-11","0.00893920770499368","0.000666354144111929"]
["P-hsa04630-33","Jak-STAT signaling pathway: RAF1","DOWN","3.91476072626044e-27","0.00966548110458986","6.39693324037803e-09"]
["P-hsa04622-11","RIG-I-like receptor signaling pathway: IRF7","UP","6.69106747490492e-09","1.02007481004217e-15","0.00984704004210598"]
["P-hsa04520-34","Adherens junction: RHOA","DOWN","1.47754492551863e-11","0.00989126619350099","8.99876604345706e-18"]
["P-hsa03320-21","PPAR signaling pathway: ACAA1","DOWN","1.14188571354343e-26","1.81454853094809e-60","0.0110362241128595"]
["P-hsa05031-59","Amphetamine addiction: PPP3CA","DOWN","4.8143596690876e-06","1.37111646329555e-05","0.0124061243164956"]
["P-hsa04151-100","PI3K-Akt signaling pathway: PRKCA","DOWN","8.77305824098993e-13","1.15239687722124e-10","0.0129437311763338"]
["P-hsa05205-129","Proteoglycans in cancer: AKT3*","DOWN","6.21366137553059e-40","0.0136798119618758","5.77513246775426e-14"]
["P-hsa04919-99","Thyroid hormone signaling pathway: WNT4","DOWN","0.0144664795518518","7.7113438700566e-35","1.205799565903e-07"]
["P-hsa05205-17","Proteoglycans in cancer: AKT3","DOWN","1.43880466784939e-08","0.0152975618556805","1.42652886099775e-36"]
["P-hsa04662-6","B cell receptor signaling pathway: NFKB1","UP","0.00920599437252097","0.00685170515108275","1.93909199140669e-05"]
["P-hsa04151-105 62","PI3K-Akt signaling pathway: CCND1 CDK2","UP","2.54715575338673e-06","4.27181817610286e-23","0.0162172253826799"]
["P-hsa05200-5","Pathways in cancer: CASP3*","DOWN","0.0168260574655092","5.32396658696102e-05","4.80567917565729e-22"]
["P-hsa05210-7","Colorectal cancer: CASP3*","DOWN","0.0168260574655092","5.32396658696102e-05","4.80567917565729e-22"]
["P-hsa04623-17","Cytosolic DNA-sensing pathway: NFKB1","UP","3.35006122238833e-06","3.37302345669032e-47","0.0171697285661694"]
["P-hsa04340-49","Hedgehog signaling pathway: CCND1","UP","1.2596079751051e-09","0.0109098898146562","0.00627130388029687"]
["P-hsa04919-88","Thyroid hormone signaling pathway: FOXO1","DOWN","8.69334926173583e-50","0.0178758705665339","3.41982548323265e-07"]
["P-hsa04213-55","Longevity regulating pathway - multiple species: CRYAB","UP","2.22758778700845e-25","0.010086057297318","0.00887078549574774"]
["P-hsa04972-21","Pancreatic secretion: KCNQ1","DOWN","0.0194087889025091","5.39415670495584e-36","2.93237814831533e-08"]
["P-hsa04722-73 77","Neurotrophin signaling pathway: NGFRAP1 YWHAE","DOWN","6.5495470084649e-15","0.0203226957527633","1.86338511270011e-14"]
["P-hsa05162-28 34","Measles: IRF9 STAT1","UP","0.0110917772329643","4.43396778137571e-31","0.00930486718890793"]
["P-hsa04910-17","Insulin signaling pathway: D-Glucose","DOWN","3.46793358420527e-86","0.0206806615992249","1.66021795340355e-11"]
["P-hsa04390-60","Hippo signaling pathway: CTGF*","DOWN","6.18216001188183e-22","0.0210405406725384","3.82457763769526e-11"]
["P-hsa04914-34","Progesterone-mediated oocyte maturation: MAPK14","DOWN","0.0214336222179426","3.49806286919466e-14","1.17639440164093e-26"]
["P-hsa04915-28","Estrogen signaling pathway: KCNJ3","UP","0.0143086523944703","1.94571067625202e-56","0.00914463570597377"]
["P-hsa04211-2","Longevity regulating pathway - mammal: RPS6KB1","UP","3.32766557875361e-08","0.0240861219969169","2.289895800812e-18"]
["P-hsa04022-57","cGMP-PKG signaling pathway: GMP","DOWN","3.17998518209002e-55","0.0244987008068919","7.03282711136918e-51"]
["P-hsa04152-64","AMPK signaling pathway: ACACB","DOWN","1.44578279975818e-31","0.0248824368827533","8.55652029370203e-11"]
["P-hsa04630-7","Jak-STAT signaling pathway: BCL2","UP","1.48333604623086e-29","0.0260233272400473","1.51083814653735e-32"]
["P-hsa04710-11","Circadian rhythm: CRY1","DOWN","2.16062322179318e-05","0.00314894274752084","0.0236902562318693"]
["P-hsa04012-47","ErbB signaling pathway: PRKCA","DOWN","2.15671558046761e-29","1.3543103680285e-15","0.027260123408103"]
["P-hsa03320-44","PPAR signaling pathway: FABP1","DOWN","1.28108529336519e-14","8.92610710488632e-40","0.0273745185993993"]
["P-hsa05211-31","Renal cell carcinoma: SOS1","DOWN","3.97225693773046e-38","0.0282517057728268","1.72560515807493e-09"]
["P-hsa05160-22 23","Hepatitis C: STAT1 IRF9","UP","0.0286344108734527","2.24199377324663e-15","1.11966918516765e-10"]
["P-hsa04152-15","AMPK signaling pathway: FOXO1","DOWN","5.104573967304e-18","0.0305107033705288","2.88080355351635e-21"]
["P-hsa05164-23","Influenza A: IRF3","UP","0.000742518580245236","6.43872828579962e-27","0.0299222385749646"]
["P-hsa04010-118","MAPK signaling pathway: JUN","UP","0.0152808885919158","4.64018796733115e-80","0.0161568563426753"]
["P-hsa05205-183","Proteoglycans in cancer: VEGFA*","UP","5.64497434987959e-06","3.08344779754429e-38","0.0317235167245815"]
["P-hsa04726-38","Serotonergic synapse: PLA2G4B","DOWN","5.23999576417142e-32","2.47102878649233e-23","0.0317292082356726"]
["P-hsa05020-48","Prion diseases: SOD1","DOWN","7.02178010594405e-07","6.70816268763134e-15","0.0322015625989366"]
["P-hsa05231-60","Choline metabolism in cancer: PRKCA","DOWN","1.11727358823562e-13","0.00490854027577097","0.0295069257306331"]
["P-hsa04972-23","Pancreatic secretion: KCNMA1","DOWN","0.000752865687672003","0.0338056710966925","6.09065329160061e-09"]
["P-hsa05031-98","Amphetamine addiction: FOS","DOWN","2.86787135975073e-17","1.42300412730496e-27","0.0354047659737893"]
["P-hsa05321-138","Inflammatory bowel disease (IBD): IFNG**","UP","0.0351911266312024","2.84900574647305e-24","0.00259261292114067"]
["P-hsa04922-17","Glucagon signaling pathway: PKM","UP","1.04837680993471e-08","0.00767777630011357","0.0307420742528305"]
["P-hsa04010-66","MAPK signaling pathway: TP53","UP","0.0406593865658075","9.83060001021983e-62","8.84748870995995e-11"]
["P-hsa04920-37","Adipocytokine signaling pathway: IRS1","UP","0.0404747680310425","0.0005641695116318","2.21391923224267e-10"]
["P-hsa05162-62","Measles: IL12A","DOWN","0.00604787611141966","2.38178661180654e-07","0.0356550545128167"]
["P-hsa05215-30","Prostate cancer: TP53","UP","0.0413145386130137","1.24212546023049e-06","0.00125057813702404"]
["P-hsa04014-41","Ras signaling pathway: RAC1*","DOWN","0.0344437234274377","0.00991217665406779","1.04584352165912e-05"]
["P-hsa05014-32 34","Amyotrophic lateral sclerosis (ALS): NEFM PRPH","DOWN","9.88731985242807e-15","0.0453652656964049","3.38786356771769e-10"]
["P-hsa04724-44","Glutamatergic synapse: PRKACA*","DOWN","4.61664683040629e-15","1.13585910053607e-06","0.0458232496742913"]
["P-hsa04610-58","Complement and coagulation cascades: F2RL2","UP","0.0246182938940231","2.57430256562437e-19","0.0220377670885787"]
["P-hsa05211-27","Renal cell carcinoma: VEGFA*","UP","0.000618250417108571","1.15961055720813e-67","0.0479684301135529"]
["P-hsa04152-60","AMPK signaling pathway: EEF2","UP","2.9058645331665e-26","0.0487730219272017","1.03216273170259e-08"]
["P-hsa05150-40","Staphylococcus aureus infection: FCGR1A","UP","0.00184971227185095","2.1919506532779e-30","0.0470013227149436"]
["P-hsa04911-31","Insulin secretion: CAMK2A","DOWN","5.38288523739688e-05","0.0489608292814413","8.55855513860269e-17"]
["P-hsa05150-48","Staphylococcus aureus infection: C3AR1","UP","0.0123485129644503","5.18992289553831e-16","0.0372380940433881"]
["P-hsa04622-5 33","RIG-I-like receptor signaling pathway: MAVS TMEM173","UP","2.86276513551692e-30","1.1324640498303e-29","0.0496689787128749"]
["P-hsa04064-36","NF-kappa B signaling pathway: PLCG1","UP","0.0482214491371624","5.2279186977772e-39","0.00365919240462962"]
["P-hsa04931-67","Insulin resistance: IKBKB**","UP","0.00851708301485627","0.0458761987312964","0.00262999719349457"]