{"text_format":"3","workbook":"xlsx","n_sheets":1,"sheets":["Sheet1"],"read":"whole","date_system":"1900"}

{"sheet":"Sheet1","index":0,"n_rows":260,"n_cols":10,"rows_kept":260}
["KEGG_A_class","KEGG_B_class","Pathway","out (186)","All (4681)","Pvalue","Qvalue","Pathway ID","Genes","K_IDs"]
["Organismal Systems","Endocrine system","PPAR signaling pathway",8,42,1.97455E-4,0.05114072,"ko03320","ENSMUSG00000025203;ENSMUSG00000028773;ENSMUSG00000025006;ENSMUSG00000020333;ENSMUSG00000018796;ENSMUSG00000015843;ENSMUSG00000024600;ENSMUSG00000027875","K00507+K08752+K06086+K01897+K01897+K08526+K08749+K01641"]
["Environmental Information Processing","Signal transduction","Rap1 signaling pathway",15,150,0.000798564,0.10341399,"ko04015","ENSMUSG00000020431;ENSMUSG00000024451;ENSMUSG00000019966;ENSMUSG00000038387;ENSMUSG00000032259;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000000303;ENSMUSG00000053137;ENSMUSG00000034664;ENSMUSG00000054252;ENSMUSG00000021536;ENSMUSG00000027954;ENSMUSG00000005320;ENSMUSG00000031073","K08041+K12490+K05461+K07829+K04145+K04358+K05093+K05689+K04441+K06476+K05094+K08042+K05462+K05095+K22603"]
["Environmental Information Processing","Signaling molecules and interaction","Cytokine-cytokine receptor interaction",10,87,0.002149266,0.11040553,"ko04060","ENSMUSG00000020007;ENSMUSG00000016529;ENSMUSG00000003227;ENSMUSG00000041872;ENSMUSG00000023047;ENSMUSG00000037944;ENSMUSG00000038508;ENSMUSG00000017652;ENSMUSG00000063727;ENSMUSG00000068105","K05136+K05443+K05162+K05494+K04672+K04182+K05504+K03160+K05148+K05151"]
["Organismal Systems","Sensory system","Taste transduction",5,24,2.153477E-3,0.11040553,"ko04742","ENSMUSG00000042644;ENSMUSG00000020704;ENSMUSG00000057182;ENSMUSG00000070687;ENSMUSG00000032269","K04960+K04828+K04836+K04153+K04819"]
["Environmental Information Processing","Signal transduction","Apelin signaling pathway",11,102,2.19133E-3,0.11040553,"ko04371","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000038387;ENSMUSG00000030592;ENSMUSG00000020901;ENSMUSG00000000303;ENSMUSG00000059741;ENSMUSG00000038418;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K04960+K04503+K07829+K04961+K21290+K05689+K12749+K09203+K08042+K04549"]
["Environmental Information Processing","Signal transduction","MAPK signaling pathway",18,220,0.002557657,0.11040553,"ko04010","ENSMUSG00000015656;ENSMUSG00000025408;ENSMUSG00000019966;ENSMUSG00000038387;ENSMUSG00000019960;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000053137;ENSMUSG00000090877;ENSMUSG00000021549;ENSMUSG00000037887;ENSMUSG00000021453;ENSMUSG00000054252;ENSMUSG00000032508;ENSMUSG00000027954;ENSMUSG00000005320;ENSMUSG00000031073;ENSMUSG00000109061","K03283+K04452+K05461+K07829+K21946+K04358+K05093+K04441+K03283+K04352+K04459+K04402+K05094+K04729+K05462+K05095+K22603+K04431"]
["Organismal Systems","Immune system","Intestinal immune network for IgA production",4,17,0.003823705,0.14147709,"ko04672","ENSMUSG00000016529;ENSMUSG00000020310;ENSMUSG00000017652;ENSMUSG00000068105","K05443+K06779+K03160+K05151"]
["Organismal Systems","Immune system","Platelet activation",9,81,0.004475479,0.14489363,"ko04611","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000021457;ENSMUSG00000020901;ENSMUSG00000053137;ENSMUSG00000034664;ENSMUSG00000021536;ENSMUSG00000050675;ENSMUSG00000050761","K08041+K04960+K05855+K21290+K04441+K06476+K08042+K06261+K06262"]
["Human Diseases","Cancers","Transcriptional misregulation in cancers",11,124,0.009747021,0.2804976,"ko05202","ENSMUSG00000013089;ENSMUSG00000025408;ENSMUSG00000019960;ENSMUSG00000021453;ENSMUSG00000022508;ENSMUSG00000015843;ENSMUSG00000030717;ENSMUSG00000027793;ENSMUSG00000035158;ENSMUSG00000017652;ENSMUSG00000017737","K15593+K04452+K21946+K04402+K15618+K08526+K15626+K06627+K09455+K03160+K01403"]
["Human Diseases","Immune diseases","Autoimmune thyroid disease",3,13,0.01314978,0.30961755,"ko05320","ENSMUSG00000016529;ENSMUSG00000067212;ENSMUSG00000017652","K05443+K06751+K03160"]
["Human Diseases","Immune diseases","Allograft rejection",3,13,0.01314978,0.30961755,"ko05330","ENSMUSG00000016529;ENSMUSG00000067212;ENSMUSG00000017652","K05443+K06751+K03160"]
["Human Diseases","Cancers","Melanoma",6,53,0.01764881,0.33652434,"ko05218","ENSMUSG00000070348;ENSMUSG00000050917;ENSMUSG00000000303;ENSMUSG00000021453;ENSMUSG00000035158;ENSMUSG00000031073","K04503+K04358+K05689+K04402+K09455+K22603"]
["Organismal Systems","Immune system","Antigen processing and presentation",5,39,0.01804033,0.33652434,"ko04612","ENSMUSG00000015656;ENSMUSG00000003814;ENSMUSG00000026864;ENSMUSG00000090877;ENSMUSG00000067212","K03283+K08057+K09490+K03283+K06751"]
["Human Diseases","Cancers","Central carbon metabolism in cancer",6,55,0.02088379,0.33652434,"ko05230","ENSMUSG00000063229;ENSMUSG00000032294;ENSMUSG00000025161;ENSMUSG00000020277;ENSMUSG00000030849;ENSMUSG00000054252","K00016+K00873+K08180+K00850+K05093+K05094"]
["Human Diseases","Immune diseases","Asthma",2,6,0.02119664,0.33652434,"ko05310","ENSMUSG00000016529;ENSMUSG00000017652","K05443+K03160"]
["Human Diseases","Cancers","Pathways in cancer",23,378,0.02482901,0.33652434,"ko05200","ENSMUSG00000020431;ENSMUSG00000070348;ENSMUSG00000019966;ENSMUSG00000031987;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000000303;ENSMUSG00000035105;ENSMUSG00000003436;ENSMUSG00000024521;ENSMUSG00000021453;ENSMUSG00000030170;ENSMUSG00000024140;ENSMUSG00000034664;ENSMUSG00000054252;ENSMUSG00000015843;ENSMUSG00000035158;ENSMUSG00000021536;ENSMUSG00000005320;ENSMUSG00000031073;ENSMUSG00000012282;ENSMUSG00000038811;ENSMUSG00000017737","K08041+K04503+K05461+K09592+K04358+K05093+K05689+K09592+K06051+K10131+K04402+K00444+K09095+K06476+K05094+K08526+K09455+K08042+K05095+K22603+K00714+K04549+K01403"]
["Organismal Systems","Digestive system","Gastric acid secretion",5,44,0.02903985,0.33652434,"ko04971","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000028962;ENSMUSG00000021536;ENSMUSG00000044708","K08041+K04960+K13855+K08042+K05003"]
["Metabolism","Carbohydrate metabolism","Fructose and mannose metabolism",4,30,0.02948002,0.33652434,"ko00051","ENSMUSG00000020277;ENSMUSG00000017390;ENSMUSG00000026409;ENSMUSG00000025648","K00850+K01623+K19029+K19030"]
["Organismal Systems","Endocrine system","Parathyroid hormone synthesis, secretion and action",7,76,0.03026534,0.33652434,"ko04928","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000020733;ENSMUSG00000001494;ENSMUSG00000015843;ENSMUSG00000038418;ENSMUSG00000021536","K08041+K04960+K13365+K16834+K08526+K09203+K08042"]
["Human Diseases","Infectious diseases","Toxoplasmosis",7,76,0.03026534,0.33652434,"ko05145","ENSMUSG00000015656;ENSMUSG00000020901;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000090877;ENSMUSG00000032508;ENSMUSG00000017652","K03283+K21290+K04441+K05443+K03283+K04729+K03160"]
["Organismal Systems","Endocrine system","Cortisol synthesis and secretion",5,45,0.03165368,0.33652434,"ko04927","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000049265;ENSMUSG00000021536;ENSMUSG00000032323","K08041+K04960+K04914+K08042+K00498"]
["Metabolism","Carbohydrate metabolism","Pyruvate metabolism",4,31,0.03282921,0.33652434,"ko00620","ENSMUSG00000063229;ENSMUSG00000032294;ENSMUSG00000035637;ENSMUSG00000030621","K00016+K00873+K00049+K00029"]
["Human Diseases","Cancers","Gastric cancer",9,112,0.03302101,0.33652434,"ko05226","ENSMUSG00000070348;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000000303;ENSMUSG00000021453;ENSMUSG00000030170;ENSMUSG00000015843;ENSMUSG00000031073;ENSMUSG00000012282","K04503+K04358+K05093+K05689+K04402+K00444+K08526+K22603+K00714"]
["Metabolism","Carbohydrate metabolism","Glycolysis / Gluconeogenesis",5,46,0.03441051,0.33652434,"ko00010","ENSMUSG00000063229;ENSMUSG00000032294;ENSMUSG00000020277;ENSMUSG00000017390;ENSMUSG00000029171","K00016+K00873+K00850+K01623+K15779"]
["Organismal Systems","Digestive system","Salivary secretion",5,47,0.03731198,0.33652434,"ko04970","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000028962;ENSMUSG00000021536;ENSMUSG00000031489","K08041+K04960+K13855+K08042+K04143"]
["Human Diseases","Infectious diseases","Malaria",3,19,0.0374269,0.33652434,"ko05144","ENSMUSG00000016529;ENSMUSG00000032508;ENSMUSG00000017652","K05443+K04729+K03160"]
["Environmental Information Processing","Signal transduction","PI3K-Akt signaling pathway",15,230,0.0386978,0.33652434,"ko04151","ENSMUSG00000020108;ENSMUSG00000070348;ENSMUSG00000019966;ENSMUSG00000021457;ENSMUSG00000020901;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000019970;ENSMUSG00000034664;ENSMUSG00000054252;ENSMUSG00000027570;ENSMUSG00000027954;ENSMUSG00000005320;ENSMUSG00000031073;ENSMUSG00000038811","K08270+K04503+K05461+K05855+K21290+K04358+K05093+K13302+K06476+K05094+K08131+K05462+K05095+K22603+K04549"]
["Organismal Systems","Immune system","Hematopoietic cell lineage",4,33,0.04016968,0.33652434,"ko04640","ENSMUSG00000019966;ENSMUSG00000034664;ENSMUSG00000050675;ENSMUSG00000050761","K05461+K06476+K06261+K06262"]
["Human Diseases","Cancers","Thyroid cancer",4,33,0.04016968,0.33652434,"ko05216","ENSMUSG00000070348;ENSMUSG00000000303;ENSMUSG00000021453;ENSMUSG00000015843","K04503+K05689+K04402+K08526"]
["Organismal Systems","Nervous system","Cholinergic synapse",7,81,0.0408537,0.33652434,"ko04725","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000020901;ENSMUSG00000100241;ENSMUSG00000056258;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K04960+K21290+K14636+K04928+K08042+K04549"]
["Organismal Systems","Endocrine system","Ovarian Steroidogenesis",3,20,0.04278027,0.33652434,"ko04913","ENSMUSG00000020431;ENSMUSG00000021536;ENSMUSG00000032323","K08041+K08042+K00498"]
["Organismal Systems","Endocrine system","Insulin secretion",5,49,0.04355416,0.33652434,"ko04911","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000061601;ENSMUSG00000000794;ENSMUSG00000021536","K08041+K04960+K16882+K04944+K08042"]
["Human Diseases","Infectious diseases","Legionellosis",4,34,0.04416229,0.33652434,"ko05134","ENSMUSG00000015656;ENSMUSG00000078566;ENSMUSG00000090877;ENSMUSG00000032508","K03283+K15464+K03283+K04729"]
["Environmental Information Processing","Signal transduction","Phospholipase D signaling pathway",8,100,0.04417694,0.33652434,"ko04072","ENSMUSG00000020431;ENSMUSG00000019966;ENSMUSG00000038387;ENSMUSG00000021457;ENSMUSG00000020901;ENSMUSG00000040265;ENSMUSG00000021536;ENSMUSG00000034731","K08041+K05461+K07829+K05855+K21290+K01528+K08042+K00901"]
["Human Diseases","Cancers","Bladder cancer",4,35,0.04836979,0.35104479,"ko05219","ENSMUSG00000070348;ENSMUSG00000000303;ENSMUSG00000054252;ENSMUSG00000017737","K04503+K05689+K05094+K01403"]
["Metabolism","Lipid metabolism","Glycerophospholipid metabolism",6,67,0.04879387,0.35104479,"ko00564","ENSMUSG00000036833;ENSMUSG00000029314;ENSMUSG00000009995;ENSMUSG00000052160;ENSMUSG00000070644;ENSMUSG00000034731","K14676+K13506+K13511+K16860+K00894+K00901"]
["Organismal Systems","Endocrine system","GnRH signaling pathway",6,68,0.05182509,0.36277563,"ko04912","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000053137;ENSMUSG00000038418;ENSMUSG00000021536;ENSMUSG00000109061","K08041+K04960+K04441+K09203+K08042+K04431"]
["Human Diseases","Cardiovascular diseases","Dilated cardiomyopathy (DCM)",5,52,0.05402864,0.365052,"ko05414","ENSMUSG00000020431;ENSMUSG00000034664;ENSMUSG00000059741;ENSMUSG00000021536;ENSMUSG00000035458","K08041+K06476+K12749+K08042+K12044"]
["Organismal Systems","Endocrine system","Aldosterone synthesis and secretion",6,69,0.05496922,0.365052,"ko04925","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000049265;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000032323","K08041+K04960+K04914+K12323+K08042+K00498"]
["Organismal Systems","Endocrine system","Melanogenesis",6,70,0.05822669,0.37701782,"ko04916","ENSMUSG00000020431;ENSMUSG00000019966;ENSMUSG00000030170;ENSMUSG00000035158;ENSMUSG00000021536;ENSMUSG00000012282","K08041+K05461+K00444+K09455+K08042+K00714"]
["Organismal Systems","Circulatory system","Vascular smooth muscle contraction",6,71,0.06159779,0.38911775,"ko04270","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000041046;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000001240","K08041+K04960+K08449+K12323+K08042+K08448"]
["Organismal Systems","Immune system","C-type lectin receptor signaling pathway",6,72,0.06508268,0.39744735,"ko04625","ENSMUSG00000042644;ENSMUSG00000038387;ENSMUSG00000021457;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000018819","K04960+K07829+K05855+K04441+K05443+K14957"]
["Metabolism","Lipid metabolism","Fatty acid biosynthesis",2,11,0.06823291,0.39744735,"ko00061","ENSMUSG00000020333;ENSMUSG00000018796","K01897+K01897"]
["Organismal Systems","Endocrine system","Glucagon signaling pathway",6,73,0.06868138,0.39744735,"ko04922","ENSMUSG00000063229;ENSMUSG00000032294;ENSMUSG00000030815;ENSMUSG00000042644;ENSMUSG00000020277;ENSMUSG00000021536","K00016+K00873+K00871+K04960+K00850+K08042"]
["Environmental Information Processing","Signal transduction","FoxO signaling pathway",8,110,0.06989631,0.39744735,"ko04068","ENSMUSG00000078566;ENSMUSG00000018566;ENSMUSG00000070348;ENSMUSG00000019970;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000021453;ENSMUSG00000022508","K15464+K07191+K04503+K13302+K04441+K05443+K04402+K15618"]
["Organismal Systems","Endocrine system","Regulation of lipolysis in adipocyte",4,40,0.07258867,0.39744735,"ko04923","ENSMUSG00000020431;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000031489","K08041+K12323+K08042+K04143"]
["Metabolism","Carbohydrate metabolism","Pentose phosphate pathway",3,25,0.07479518,0.39744735,"ko00030","ENSMUSG00000020277;ENSMUSG00000017390;ENSMUSG00000029171","K00850+K01623+K15779"]
["Organismal Systems","Nervous system","GABAergic synapse",5,58,0.07899122,0.39744735,"ko04727","ENSMUSG00000020431;ENSMUSG00000006930;ENSMUSG00000038349;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K04647+K15375+K08042+K04549"]
["Human Diseases","Endocrine and metabolic diseases","Cushing syndrome",8,113,0.07909596,0.39744735,"ko04934","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000049265;ENSMUSG00000030170;ENSMUSG00000021536;ENSMUSG00000032323;ENSMUSG00000012282","K08041+K04960+K04503+K04914+K00444+K08042+K00498+K00714"]
["Human Diseases","Infectious diseases","African trypanosomiasis",2,12,0.07979638,0.39744735,"ko05143","ENSMUSG00000016529;ENSMUSG00000032508","K05443+K04729"]
["Human Diseases","Infectious diseases","Staphylococcus aureus infection",2,12,0.07979638,0.39744735,"ko05150","ENSMUSG00000016529;ENSMUSG00000028979","K05443+K03993"]
["Human Diseases","Immune diseases","Primary immunodeficiency",2,12,0.07979638,0.39744735,"ko05340","ENSMUSG00000017652;ENSMUSG00000068105","K03160+K05151"]
["Environmental Information Processing","Signal transduction","Calcium signaling pathway",7,95,0.08228144,0.40128318,"ko04020","ENSMUSG00000020431;ENSMUSG00000030815;ENSMUSG00000042644;ENSMUSG00000030592;ENSMUSG00000010660;ENSMUSG00000021536;ENSMUSG00000031489","K08041+K00871+K04960+K04961+K05857+K08042+K04143"]
["Organismal Systems","Sensory system","Inflammatory mediator regulation of TRP channels",5,59,0.08366522,0.40128318,"ko04750","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000053137;ENSMUSG00000020704;ENSMUSG00000021536","K08041+K04960+K04441+K04828+K08042"]
["Human Diseases","Drug resistance","Endocrine resistance",6,78,0.08837358,0.41608682,"ko01522","ENSMUSG00000020431;ENSMUSG00000070348;ENSMUSG00000003436;ENSMUSG00000053137;ENSMUSG00000021536;ENSMUSG00000017737","K08041+K04503+K06051+K04441+K08042+K01403"]
["Metabolism","Lipid metabolism","Steroid hormone biosynthesis",2,13,0.09191394,0.41608682,"ko00140","ENSMUSG00000032323;ENSMUSG00000054545","K00498+K00699"]
["Organismal Systems","Development","Osteoclast differentiation",6,79,0.09264826,0.41608682,"ko04380","ENSMUSG00000021457;ENSMUSG00000053137;ENSMUSG00000052837;ENSMUSG00000035158;ENSMUSG00000063727;ENSMUSG00000109061","K05855+K04441+K09028+K09455+K05148+K04431"]
["Human Diseases","Infectious diseases","Kaposi sarcoma-associated herpesvirus infection",9,137,0.09348139,0.41608682,"ko05167","ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000021457;ENSMUSG00000020901;ENSMUSG00000053137;ENSMUSG00000067212;ENSMUSG00000003283;ENSMUSG00000038811;ENSMUSG00000109061","K04960+K04503+K05855+K21290+K04441+K06751+K08893+K04549+K04431"]
["Organismal Systems","Digestive system","Pancreatic secretion",4,44,0.09563496,0.41608682,"ko04972","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000028962;ENSMUSG00000021536","K08041+K04960+K13855+K08042"]
["Environmental Information Processing","Signal transduction","Ras signaling pathway",10,158,0.09639077,0.41608682,"ko04014","ENSMUSG00000019966;ENSMUSG00000038387;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000021549;ENSMUSG00000054252;ENSMUSG00000027954;ENSMUSG00000005320;ENSMUSG00000031073;ENSMUSG00000038811","K05461+K07829+K04358+K05093+K04352+K05094+K05462+K05095+K22603+K04549"]
["Environmental Information Processing","Signaling molecules and interaction","Cell adhesion molecules (CAMs)",5,62,0.09854193,0.41839934,"ko04514","ENSMUSG00000039419;ENSMUSG00000000303;ENSMUSG00000020310;ENSMUSG00000067212;ENSMUSG00000017652","K07380+K05689+K06779+K06751+K03160"]
["Organismal Systems","Endocrine system","Estrogen signaling pathway",6,82,0.1061303,0.43990903,"ko04915","ENSMUSG00000015656;ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000090877;ENSMUSG00000021536;ENSMUSG00000017737","K03283+K08041+K04960+K03283+K08042+K01403"]
["Environmental Information Processing","Signal transduction","cAMP signaling pathway",8,121,0.1070049,0.43990903,"ko04024","ENSMUSG00000020431;ENSMUSG00000024451;ENSMUSG00000038387;ENSMUSG00000032259;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000070687;ENSMUSG00000035458","K08041+K12490+K07829+K04145+K12323+K08042+K04153+K12044"]
["Environmental Information Processing","Signal transduction","AMPK signaling pathway",7,103,0.1139611,0.44418964,"ko04152","ENSMUSG00000025203;ENSMUSG00000018566;ENSMUSG00000020277;ENSMUSG00000070348;ENSMUSG00000026409;ENSMUSG00000027793;ENSMUSG00000025648","K00507+K07191+K00850+K04503+K19029+K06627+K19030"]
["Organismal Systems","Endocrine system","Oxytocin signaling pathway",7,103,0.1139611,0.44418964,"ko04921","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000030592;ENSMUSG00000020901;ENSMUSG00000027931;ENSMUSG00000021536","K08041+K04960+K04503+K04961+K21290+K12323+K08042"]
["Environmental Information Processing","Signaling molecules and interaction","ECM-receptor interaction",4,47,0.1149062,0.44418964,"ko04512","ENSMUSG00000034664;ENSMUSG00000027570;ENSMUSG00000050675;ENSMUSG00000050761","K06476+K08131+K06261+K06262"]
["Organismal Systems","Endocrine system","Thyroid hormone synthesis",4,47,0.1149062,0.44418964,"ko04918","ENSMUSG00000020431;ENSMUSG00000026864;ENSMUSG00000042644;ENSMUSG00000021536","K08041+K09490+K04960+K08042"]
["Cellular Processes","Cellular community - eukaryotes","Signaling pathways regulating pluripotency of stem cells",7,104,0.1183197,0.44510445,"ko04550","ENSMUSG00000030849;ENSMUSG00000053137;ENSMUSG00000030170;ENSMUSG00000054252;ENSMUSG00000066652;ENSMUSG00000005320;ENSMUSG00000012282","K05093+K04441+K00444+K05094+K04668+K05095+K00714"]
["Cellular Processes","Cellular community - eukaryotes","Gap junction",5,66,0.1202985,0.44510445,"ko04540","ENSMUSG00000020431;ENSMUSG00000001473;ENSMUSG00000042644;ENSMUSG00000032259;ENSMUSG00000021536","K08041+K07375+K04960+K04145+K08042"]
["Human Diseases","Infectious diseases","Chagas disease (American trypanosomiasis)",5,66,0.1202985,0.44510445,"ko05142","ENSMUSG00000020431;ENSMUSG00000003814;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000032508","K08041+K08057+K04441+K05443+K04729"]
["Organismal Systems","Digestive system","Bile secretion",3,31,0.1233619,0.45001031,"ko04976","ENSMUSG00000020431;ENSMUSG00000028962;ENSMUSG00000021536","K08041+K13855+K08042"]
["Human Diseases","Cancers","Breast cancer",7,106,0.1272937,0.45790373,"ko05224","ENSMUSG00000070348;ENSMUSG00000050917;ENSMUSG00000003436;ENSMUSG00000021453;ENSMUSG00000030170;ENSMUSG00000031073;ENSMUSG00000012282","K04503+K04358+K06051+K04402+K00444+K22603+K00714"]
["Organismal Systems","Environmental adaptation","Circadian entrainment",5,68,0.131957,0.46817621,"ko04713","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000030592;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K04960+K04961+K08042+K04549"]
["Cellular Processes","Transport and catabolism","Endocytosis",12,216,0.1490603,0.51530364,"ko04144","ENSMUSG00000015656;ENSMUSG00000042249;ENSMUSG00000024451;ENSMUSG00000024104;ENSMUSG00000030849;ENSMUSG00000040265;ENSMUSG00000090877;ENSMUSG00000067212;ENSMUSG00000054252;ENSMUSG00000056185;ENSMUSG00000005320;ENSMUSG00000046854","K03283+K00910+K12490+K18462+K05093+K01528+K03283+K06751+K05094+K17920+K05095+K13712"]
["Genetic Information Processing","Folding, sorting and degradation","Protein processing in endoplasmic reticulum",9,152,0.1492192,0.51530364,"ko04141","ENSMUSG00000015656;ENSMUSG00000003814;ENSMUSG00000025408;ENSMUSG00000026864;ENSMUSG00000041556;ENSMUSG00000009092;ENSMUSG00000039234;ENSMUSG00000090877;ENSMUSG00000109061","K03283+K08057+K04452+K09490+K10099+K13989+K14007+K03283+K04431"]
["Human Diseases","Neurodegenerative diseases","Prion diseases",2,18,0.1587872,0.54029115,"ko05020","ENSMUSG00000026864;ENSMUSG00000038418","K09490+K09203"]
["Human Diseases","Cardiovascular diseases","Viral myocarditis",3,35,0.1606271,0.54029115,"ko05416","ENSMUSG00000070348;ENSMUSG00000067212;ENSMUSG00000017652","K04503+K06751+K03160"]
["Organismal Systems","Aging","Longevity regulating pathway - multiple species",4,54,0.1656686,0.54314136,"ko04213","ENSMUSG00000015656;ENSMUSG00000020431;ENSMUSG00000090877;ENSMUSG00000021536","K03283+K08041+K03283+K08042"]
["Organismal Systems","Endocrine system","Adipocytokine signaling pathway",4,54,0.1656686,0.54314136,"ko04920","ENSMUSG00000018566;ENSMUSG00000020333;ENSMUSG00000018796;ENSMUSG00000015843","K07191+K01897+K01897+K08526"]
["Human Diseases","Infectious diseases","HTLV-I infection",11,202,0.1782094,0.55325368,"ko05166","ENSMUSG00000020431;ENSMUSG00000003814;ENSMUSG00000070348;ENSMUSG00000038387;ENSMUSG00000067212;ENSMUSG00000030170;ENSMUSG00000038418;ENSMUSG00000021536;ENSMUSG00000017652;ENSMUSG00000012282;ENSMUSG00000068105","K08041+K08057+K04503+K07829+K06751+K00444+K09203+K08042+K03160+K00714+K05151"]
["Human Diseases","Infectious diseases","Leishmaniasis",3,37,0.1804013,0.55325368,"ko05140","ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000032508","K04441+K05443+K04729"]
["Organismal Systems","Immune system","Toll-like receptor signaling pathway",4,56,0.1814533,0.55325368,"ko04620","ENSMUSG00000053137;ENSMUSG00000032508;ENSMUSG00000017652;ENSMUSG00000109061","K04441+K04729+K03160+K04431"]
["Human Diseases","Substance dependence","Morphine addiction",4,56,0.1814533,0.55325368,"ko05032","ENSMUSG00000020431;ENSMUSG00000042249;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K00910+K08042+K04549"]
["Organismal Systems","Immune system","Chemokine signaling pathway",7,117,0.1823802,0.55325368,"ko04062","ENSMUSG00000020431;ENSMUSG00000042249;ENSMUSG00000020143;ENSMUSG00000037944;ENSMUSG00000021536;ENSMUSG00000003283;ENSMUSG00000038811","K08041+K00910+K12367+K04182+K08042+K08893+K04549"]
["Organismal Systems","Circulatory system","Adrenergic signaling in cardiomyocytes",6,97,0.1871004,0.55325368,"ko04261","ENSMUSG00000020431;ENSMUSG00000020901;ENSMUSG00000053137;ENSMUSG00000059741;ENSMUSG00000021536;ENSMUSG00000035458","K08041+K21290+K04441+K12749+K08042+K12044"]
["Metabolism","Carbohydrate metabolism","Galactose metabolism",2,20,0.187541,0.55325368,"ko00052","ENSMUSG00000020277;ENSMUSG00000029171","K00850+K15779"]
["Environmental Information Processing","Signal transduction","NF-kappa B signaling pathway",4,57,0.1895281,0.55325368,"ko04064","ENSMUSG00000021457;ENSMUSG00000032508;ENSMUSG00000017652;ENSMUSG00000068105","K05855+K04729+K03160+K05151"]
["Organismal Systems","Nervous system","Glutamatergic synapse",5,77,0.1901142,0.55325368,"ko04724","ENSMUSG00000020431;ENSMUSG00000042249;ENSMUSG00000042644;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K00910+K04960+K08042+K04549"]
["Human Diseases","Endocrine and metabolic diseases","AGE-RAGE signaling pathway in diabetic complications",5,77,0.1901142,0.55325368,"ko04933","ENSMUSG00000070348;ENSMUSG00000053137;ENSMUSG00000010660;ENSMUSG00000038418;ENSMUSG00000015452","K04503+K04441+K05857+K09203+K19722"]
["Organismal Systems","Endocrine system","Renin secretion",3,39,0.2007933,0.56060412,"ko04924","ENSMUSG00000042644;ENSMUSG00000027931;ENSMUSG00000031489","K04960+K12323+K04143"]
["Organismal Systems","Digestive system","Protein digestion and absorption",3,39,0.2007933,0.56060412,"ko04974","ENSMUSG00000079022;ENSMUSG00000004098;ENSMUSG00000027570","K16630+K19721+K08131"]
["Human Diseases","Infectious diseases","Pertussis",3,39,0.2007933,0.56060412,"ko05133","ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000032508","K04441+K05443+K04729"]
["Organismal Systems","Immune system","Complement and coagulation cascades",2,21,0.2021774,0.56060412,"ko04610","ENSMUSG00000030111;ENSMUSG00000028979","K03910+K03993"]
["Human Diseases","Infectious diseases","Epstein-Barr virus infection",9,164,0.2034625,0.56060412,"ko05169","ENSMUSG00000015656;ENSMUSG00000021457;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000090877;ENSMUSG00000067212;ENSMUSG00000027793;ENSMUSG00000017652;ENSMUSG00000109061","K03283+K05855+K04441+K05443+K03283+K06751+K06627+K03160+K04431"]
["Organismal Systems","Endocrine system","Relaxin signaling pathway",6,100,0.2056402,0.56064012,"ko04926","ENSMUSG00000020431;ENSMUSG00000053137;ENSMUSG00000021536;ENSMUSG00000038811;ENSMUSG00000017737;ENSMUSG00000109061","K08041+K04441+K08042+K04549+K01403+K04431"]
["Metabolism","Carbohydrate metabolism","Amino sugar and nucleotide sugar metabolism",3,40,0.2111883,0.56976843,"ko00520","ENSMUSG00000052102;ENSMUSG00000029171;ENSMUSG00000034744","K02564+K15779+K00884"]
["Metabolism","Xenobiotics biodegradation and metabolism","Metabolism of xenobiotics by cytochrome P450",2,22,0.2169388,0.57924896,"ko00980","ENSMUSG00000022947;ENSMUSG00000054545","K00084+K00699"]
["Human Diseases","Immune diseases","Inflammatiory bowel disease (IBD)",2,23,0.2317925,0.61259446,"ko05321","ENSMUSG00000016529;ENSMUSG00000041872","K05443+K05494"]
["Cellular Processes","Transport and catabolism","Lysosome",6,105,0.2379143,0.61619804,"ko04142","ENSMUSG00000017760;ENSMUSG00000005949;ENSMUSG00000018774;ENSMUSG00000000594;ENSMUSG00000024910;ENSMUSG00000033540","K13289+K12386+K06501+K12383+K08569+K01217"]
["Organismal Systems","Nervous system","Retrograde endocannabinoid signaling",6,105,0.2379143,0.61619804,"ko04723","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000053137;ENSMUSG00000021536;ENSMUSG00000040280;ENSMUSG00000038811","K08041+K04960+K04441+K08042+K03948+K04549"]
["Organismal Systems","Immune system","Fc epsilon RI signaling pathway",3,43,0.2430176,0.62318375,"ko04664","ENSMUSG00000021457;ENSMUSG00000053137;ENSMUSG00000109061","K05855+K04441+K04431"]
["Environmental Information Processing","Signal transduction","Hippo signaling pathway - multiple species",2,24,0.2467078,0.62577065,"ko04392","ENSMUSG00000042129;ENSMUSG00000027339","K09851+K09851"]
["Cellular Processes","Cell growth and death","p53 signaling pathway",4,64,0.2488586,0.62577065,"ko04115","ENSMUSG00000020649;ENSMUSG00000070348;ENSMUSG00000024521;ENSMUSG00000021453","K10808+K04503+K10131+K04402"]
["Metabolism","Xenobiotics biodegradation and metabolism","Drug metabolism - other enzymes",3,44,0.2538017,0.62956181,"ko00983","ENSMUSG00000020649;ENSMUSG00000025574;ENSMUSG00000054545","K10808+K00857+K00699"]
["Organismal Systems","Nervous system","Serotonergic synapse",4,65,0.2576585,0.62956181,"ko04726","ENSMUSG00000042644;ENSMUSG00000070687;ENSMUSG00000038811;ENSMUSG00000032269","K04960+K04153+K04549+K04819"]
["Human Diseases","Immune diseases","Systemic lupus erythematosus",4,65,0.2576585,0.62956181,"ko05322","ENSMUSG00000016529;ENSMUSG00000017652;ENSMUSG00000062727;ENSMUSG00000114279","K05443+K03160+K11252+K11252"]
["Human Diseases","Cancers","Basal cell carcinoma",3,45,0.2646534,0.63497999,"ko05217","ENSMUSG00000021453;ENSMUSG00000030170;ENSMUSG00000012282","K04402+K00444+K00714"]
["Cellular Processes","Cell growth and death","Apoptosis",6,109,0.2647793,0.63497999,"ko04210","ENSMUSG00000025408;ENSMUSG00000042644;ENSMUSG00000024521;ENSMUSG00000021453;ENSMUSG00000020486;ENSMUSG00000024910","K04452+K04960+K10131+K04402+K16943+K08569"]
["Metabolism","Global and overview maps","Fatty acid metabolism",3,46,0.2755617,0.6353419,"ko01212","ENSMUSG00000025203;ENSMUSG00000020333;ENSMUSG00000018796","K00507+K01897+K01897"]
["Metabolism","Nucleotide metabolism","Purine metabolism",7,133,0.2765421,0.6353419,"ko00230","ENSMUSG00000020649;ENSMUSG00000020431;ENSMUSG00000032294;ENSMUSG00000029171;ENSMUSG00000027931;ENSMUSG00000026817;ENSMUSG00000021536","K10808+K08041+K00873+K15779+K12323+K00939+K08042"]
["Organismal Systems","Environmental adaptation","Circadian rhythm",2,26,0.2766132,0.6353419,"ko04710","ENSMUSG00000030256;ENSMUSG00000020889","K03730+K03728"]
["Metabolism","Lipid metabolism","Synthesis and degradation of ketone bodies",1,8,0.2771955,0.6353419,"ko00072","ENSMUSG00000027875","K01641"]
["Metabolism","Energy metabolism","Nitrogen metabolism",1,8,0.2771955,0.6353419,"ko00910","ENSMUSG00000027555","K01672"]
["Environmental Information Processing","Signaling molecules and interaction","Neuroactive ligand-receptor interaction",4,68,0.2844059,0.64282381,"ko04080","ENSMUSG00000032259;ENSMUSG00000059763;ENSMUSG00000070687;ENSMUSG00000031489","K04145+K05051+K04153+K04143"]
["Environmental Information Processing","Signal transduction","cGMP - PKG signaling pathway",6,112,0.2854237,0.64282381,"ko04022","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000020901;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000031489","K08041+K04960+K21290+K12323+K08042+K04143"]
["Metabolism","Amino acid metabolism","Glycine, serine and threonine metabolism",2,27,0.291553,0.64540365,"ko00260","ENSMUSG00000021953;ENSMUSG00000035637","K15789+K00049"]
["Organismal Systems","Excretory system","Aldosterone-regulated sodium reabsorption",2,27,0.291553,0.64540365,"ko04960","ENSMUSG00000031618;ENSMUSG00000019970","K08555+K13302"]
["Human Diseases","Cancers","Viral carcinogenesis",8,159,0.2969374,0.64750936,"ko05203","ENSMUSG00000032294;ENSMUSG00000070348;ENSMUSG00000021457;ENSMUSG00000067212;ENSMUSG00000024521;ENSMUSG00000027793;ENSMUSG00000062727;ENSMUSG00000114279","K00873+K04503+K05855+K06751+K10131+K06627+K11252+K11252"]
["Human Diseases","Cardiovascular diseases","Hypertrophic cardiomyopathy (HCM)",3,48,0.2975043,0.64750936,"ko05410","ENSMUSG00000034664;ENSMUSG00000059741;ENSMUSG00000035458","K06476+K12749+K12044"]
["Human Diseases","Infectious diseases","Measles",4,70,0.3024664,0.65282331,"ko05162","ENSMUSG00000015656;ENSMUSG00000070348;ENSMUSG00000090877;ENSMUSG00000032508","K03283+K04503+K03283+K04729"]
["Metabolism","Metabolism of cofactors and vitamins","Ubiquinone and other terpenoid-quinone biosynthesis",1,9,0.3059654,0.65491767,"ko00130","ENSMUSG00000066735","K05357"]
["Organismal Systems","Immune system","IL-17 signaling pathway",3,50,0.3195466,0.67501086,"ko04657","ENSMUSG00000053137;ENSMUSG00000041872;ENSMUSG00000017737","K04441+K05494+K01403"]
["Cellular Processes","Cell growth and death","Apoptosis - multiple species",2,29,0.321296,0.67501086,"ko04215","ENSMUSG00000024521;ENSMUSG00000020486","K10131+K16943"]
["Human Diseases","Infectious diseases","Influenza A",5,95,0.3257989,0.67501086,"ko05164","ENSMUSG00000015656;ENSMUSG00000053137;ENSMUSG00000090877;ENSMUSG00000032508;ENSMUSG00000109061","K03283+K04441+K03283+K04729+K04431"]
["Cellular Processes","Cell growth and death","Cellular senescence",7,141,0.3277505,0.67501086,"ko04218","ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000038387;ENSMUSG00000053137;ENSMUSG00000067212;ENSMUSG00000021453;ENSMUSG00000027793","K04960+K04503+K07829+K04441+K06751+K04402+K06627"]
["Human Diseases","Infectious diseases","Human cytomegalovirus infection",8,165,0.3328111,0.67501086,"ko05163","ENSMUSG00000020431;ENSMUSG00000003814;ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000053137;ENSMUSG00000067212;ENSMUSG00000021536;ENSMUSG00000038811","K08041+K08057+K04960+K04503+K04441+K06751+K08042+K04549"]
["Metabolism","Carbohydrate metabolism","Ascorbate and aldarate metabolism",1,10,0.3335961,0.67501086,"ko00053","ENSMUSG00000054545","K00699"]
["Metabolism","Metabolism of cofactors and vitamins","Thiamine metabolism",1,10,0.3335961,0.67501086,"ko00730","ENSMUSG00000026817","K00939"]
["Organismal Systems","Endocrine system","Progesterone-mediated oocyte maturation",4,76,0.3572378,0.70662342,"ko04914","ENSMUSG00000020431;ENSMUSG00000053137;ENSMUSG00000027793;ENSMUSG00000021536","K08041+K04441+K06627+K08042"]
["Human Diseases","Cancers","Small cell lung cancer",4,76,0.3572378,0.70662342,"ko05222","ENSMUSG00000070348;ENSMUSG00000021453;ENSMUSG00000034664;ENSMUSG00000015843","K04503+K04402+K06476+K08526"]
["Organismal Systems","Endocrine system","Renin-angiotensin system",1,11,0.3601324,0.70662342,"ko04614","ENSMUSG00000017760","K13289"]
["Human Diseases","Immune diseases","Graft-versus-host disease",1,11,0.3601324,0.70662342,"ko05332","ENSMUSG00000067212","K06751"]
["Human Diseases","Cancers","Acute myeloid leukemia",3,54,0.3636277,0.7081171,"ko05221","ENSMUSG00000070348;ENSMUSG00000019960;ENSMUSG00000027793","K04503+K21946+K06627"]
["Human Diseases","Infectious diseases","Tuberculosis",5,101,0.3737118,0.7151967,"ko05152","ENSMUSG00000021457;ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000032508;ENSMUSG00000018819","K05855+K04441+K05443+K04729+K14957"]
["Human Diseases","Cancers","Endometrial cancer",3,55,0.3745967,0.7151967,"ko05213","ENSMUSG00000070348;ENSMUSG00000000303;ENSMUSG00000021453","K04503+K05689+K04402"]
["Environmental Information Processing","Signal transduction","TNF signaling pathway",4,78,0.3755473,0.7151967,"ko04668","ENSMUSG00000053137;ENSMUSG00000052837;ENSMUSG00000017737;ENSMUSG00000109061","K04441+K09028+K01403+K04431"]
["Cellular Processes","Cell motility","Regulation of actin cytoskeleton",7,150,0.3869351,0.73150504,"ko04810","ENSMUSG00000038387;ENSMUSG00000050917;ENSMUSG00000030849;ENSMUSG00000034664;ENSMUSG00000054252;ENSMUSG00000005320;ENSMUSG00000031073","K07829+K04358+K05093+K06476+K05094+K05095+K22603"]
["Human Diseases","Cancers","Prostate cancer",4,80,0.3938159,0.73759747,"ko05215","ENSMUSG00000013089;ENSMUSG00000070348;ENSMUSG00000030849;ENSMUSG00000017737","K15593+K04503+K05093+K01403"]
["Cellular Processes","Transport and catabolism","Mitophagy - animal",3,57,0.3964183,0.73759747,"ko04137","ENSMUSG00000078566;ENSMUSG00000038387;ENSMUSG00000035158","K15464+K07829+K09455"]
["Metabolism","Lipid metabolism","Fatty acid degradation",2,35,0.4081589,0.73759747,"ko00071","ENSMUSG00000020333;ENSMUSG00000018796","K01897+K01897"]
["Cellular Processes","Cell growth and death","Ferroptosis",2,35,0.4081589,0.73759747,"ko04216","ENSMUSG00000020333;ENSMUSG00000018796","K01897+K01897"]
["Human Diseases","Endocrine and metabolic diseases","Type II diabetes mellitus",2,35,0.4081589,0.73759747,"ko04930","ENSMUSG00000032294;ENSMUSG00000018566","K00873+K07191"]
["Metabolism","Carbohydrate metabolism","Pentose and glucuronate interconversions",1,13,0.4100928,0.73759747,"ko00040","ENSMUSG00000054545","K00699"]
["Metabolism","Glycan biosynthesis and metabolism","Glycosphingolipid biosynthesis - ganglio series",1,13,0.4100928,0.73759747,"ko00604","ENSMUSG00000006731","K00725"]
["Human Diseases","Infectious diseases","Human papillomavirus infection",11,251,0.413295,0.73823038,"ko05165","ENSMUSG00000032294;ENSMUSG00000020733;ENSMUSG00000070348;ENSMUSG00000018169;ENSMUSG00000023781;ENSMUSG00000067212;ENSMUSG00000030170;ENSMUSG00000034664;ENSMUSG00000027570;ENSMUSG00000027793;ENSMUSG00000012282","K00873+K13365+K04503+K05948+K09087+K06751+K00444+K06476+K08131+K06627+K00714"]
["Environmental Information Processing","Signal transduction","HIF-1 signaling pathway",4,83,0.4210619,0.74187097,"ko04066","ENSMUSG00000063229;ENSMUSG00000020277;ENSMUSG00000031987;ENSMUSG00000035105","K00016+K00850+K09592+K09592"]
["Environmental Information Processing","Signal transduction","Phosphatidylinositol signaling system",4,83,0.4210619,0.74187097,"ko04070","ENSMUSG00000042644;ENSMUSG00000026447;ENSMUSG00000010660;ENSMUSG00000034731","K04960+K00923+K05857+K00901"]
["Metabolism","Glycan biosynthesis and metabolism","Glycosaminoglycan degradation",1,14,0.4335981,0.75677782,"ko00531","ENSMUSG00000033540","K01217"]
["Organismal Systems","Immune system","Th17 cell differentiation",3,61,0.4394032,0.75677782,"ko04659","ENSMUSG00000053137;ENSMUSG00000041872;ENSMUSG00000015843","K04441+K05494+K08526"]
["Human Diseases","Cancers","Proteoglycans in cancer",7,158,0.439827,0.75677782,"ko05205","ENSMUSG00000042644;ENSMUSG00000070348;ENSMUSG00000038387;ENSMUSG00000053137;ENSMUSG00000030170;ENSMUSG00000012282;ENSMUSG00000017737","K04960+K04503+K07829+K04441+K00444+K00714+K01403"]
["Human Diseases","Endocrine and metabolic diseases","Insulin resistance",4,86,0.448018,0.75677782,"ko04931","ENSMUSG00000025220;ENSMUSG00000018566;ENSMUSG00000032715;ENSMUSG00000024600","K15719+K07191+K19518+K08749"]
["Metabolism","Carbohydrate metabolism","Inositol phosphate metabolism",3,62,0.449976,0.75677782,"ko00562","ENSMUSG00000026447;ENSMUSG00000010660;ENSMUSG00000046854","K00923+K05857+K13712"]
["Metabolism","Global and overview maps","Biosynthesis of amino acids",3,62,0.449976,0.75677782,"ko01230","ENSMUSG00000032294;ENSMUSG00000020277;ENSMUSG00000017390","K00873+K00850+K01623"]
["Human Diseases","Cancers","Non-small cell lung cancer",3,62,0.449976,0.75677782,"ko05223","ENSMUSG00000070348;ENSMUSG00000021453;ENSMUSG00000015843","K04503+K04402+K08526"]
["Metabolism","Metabolism of cofactors and vitamins","Folate biosynthesis",1,15,0.4561716,0.75736182,"ko00790","ENSMUSG00000015806","K00357"]
["Human Diseases","Endocrine and metabolic diseases","Type I diabetes mellitus",1,15,0.4561716,0.75736182,"ko04940","ENSMUSG00000067212","K06751"]
["Environmental Information Processing","Signal transduction","Hedgehog signaling pathway",2,39,0.4630403,0.76386903,"ko04340","ENSMUSG00000042249;ENSMUSG00000070348","K00910+K04503"]
["Metabolism","Carbohydrate metabolism","Butanoate metabolism",1,16,0.4778502,0.77838492,"ko00650","ENSMUSG00000027875","K01641"]
["Metabolism","Metabolism of cofactors and vitamins","Retinol metabolism",1,16,0.4778502,0.77838492,"ko00830","ENSMUSG00000054545","K00699"]
["Human Diseases","Cancers","Renal cell carcinoma",3,65,0.4811925,0.77893036,"ko05211","ENSMUSG00000031987;ENSMUSG00000035105;ENSMUSG00000024140","K09592+K09592+K09095"]
["Metabolism","Carbohydrate metabolism","Starch and sucrose metabolism",1,17,0.498669,0.7931147,"ko00500","ENSMUSG00000029171","K15779"]
["Metabolism","Glycan biosynthesis and metabolism","Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate",1,17,0.498669,0.7931147,"ko00532","ENSMUSG00000057337","K01020"]
["Organismal Systems","Immune system","NOD-like receptor signaling pathway",4,92,0.5006585,0.7931147,"ko04621","ENSMUSG00000042644;ENSMUSG00000038393;ENSMUSG00000053137;ENSMUSG00000032508","K04960+K20910+K04441+K04729"]
["Metabolism","Lipid metabolism","Glycerolipid metabolism",2,42,0.5022039,0.7931147,"ko00561","ENSMUSG00000029314;ENSMUSG00000034731","K13506+K00901"]
["Organismal Systems","Immune system","T cell receptor signaling pathway",3,68,0.5115604,0.80299481,"ko04660","ENSMUSG00000053137;ENSMUSG00000016529;ENSMUSG00000109061","K04441+K05443+K04431"]
["Organismal Systems","Nervous system","Long-term depression",2,43,0.5148471,0.80328554,"ko04730","ENSMUSG00000042644;ENSMUSG00000030592","K04960+K04961"]
["Metabolism","Glycan biosynthesis and metabolism","Mannose type O-glycan biosyntheis",1,18,0.518662,0.80439196,"ko00515","ENSMUSG00000040434","K09668"]
["Organismal Systems","Development","Axon guidance",6,146,0.5266401,0.80807663,"ko04360","ENSMUSG00000021451;ENSMUSG00000005958;ENSMUSG00000038387;ENSMUSG00000021549;ENSMUSG00000030170;ENSMUSG00000027954","K06521+K05112+K07829+K04352+K00444+K05462"]
["Environmental Information Processing","Signal transduction","Notch signaling pathway",2,44,0.5272778,0.80807663,"ko04330","ENSMUSG00000018169;ENSMUSG00000003436","K05948+K06051"]
["Metabolism","Xenobiotics biodegradation and metabolism","Drug metabolism - cytochrome P450",1,19,0.5378619,0.81937391,"ko00982","ENSMUSG00000054545","K00699"]
["Organismal Systems","Immune system","Fc gamma R-mediated phagocytosis",3,71,0.5409766,0.81937391,"ko04666","ENSMUSG00000021457;ENSMUSG00000020143;ENSMUSG00000003283","K05855+K12367+K08893"]
["Organismal Systems","Nervous system","Synaptic vesicle cycle",2,46,0.5514898,0.82759957,"ko04721","ENSMUSG00000040265;ENSMUSG00000100241","K01528+K14636"]
["Metabolism","Glycan biosynthesis and metabolism","Other types of O-glycan biosynthesis",1,20,0.5562998,0.82759957,"ko00514","ENSMUSG00000018169","K05948"]
["Metabolism","Global and overview maps","Carbon metabolism",4,99,0.5591889,0.82759957,"ko01200","ENSMUSG00000032294;ENSMUSG00000020277;ENSMUSG00000017390;ENSMUSG00000030621","K00873+K00850+K01623+K00029"]
["Organismal Systems","Endocrine system","Thyroid hormone signaling pathway",4,99,0.5591889,0.82759957,"ko04919","ENSMUSG00000070348;ENSMUSG00000026409;ENSMUSG00000010660;ENSMUSG00000015843","K04503+K19029+K05857+K08526"]
["Organismal Systems","Environmental adaptation","Thermogenesis",8,203,0.5624684,0.82772338,"ko04714","ENSMUSG00000020431;ENSMUSG00000053137;ENSMUSG00000020333;ENSMUSG00000018796;ENSMUSG00000027931;ENSMUSG00000021536;ENSMUSG00000040280;ENSMUSG00000031489","K08041+K04441+K01897+K01897+K12323+K08042+K03948+K04143"]
["Metabolism","Amino acid metabolism","Tryptophan metabolism",1,21,0.574006,0.83231849,"ko00380","ENSMUSG00000000673","K00452"]
["Metabolism","Metabolism of terpenoids and polyketides","Terpenoid backbone biosynthesis",1,21,0.574006,0.83231849,"ko00900","ENSMUSG00000027875","K01641"]
["Human Diseases","Cardiovascular diseases","Fluid shear stress and atherosclerosis",4,101,0.5752317,0.83231849,"ko05418","ENSMUSG00000053137;ENSMUSG00000034664;ENSMUSG00000017737;ENSMUSG00000109061","K04441+K06476+K01403+K04431"]
["Environmental Information Processing","Signal transduction","mTOR signaling pathway",5,128,0.5808393,0.83442388,"ko04150","ENSMUSG00000020108;ENSMUSG00000019970;ENSMUSG00000030170;ENSMUSG00000035992;ENSMUSG00000012282","K08270+K13302+K00444+K20400+K00714"]
["Organismal Systems","Nervous system","Dopaminergic synapse",4,102,0.5831302,0.83442388,"ko04728","ENSMUSG00000042644;ENSMUSG00000032259;ENSMUSG00000053137;ENSMUSG00000038811","K04960+K04145+K04441+K04549"]
["Metabolism","Lipid metabolism","Arachidonic acid metabolism",1,22,0.5910091,0.8364555,"ko00590","ENSMUSG00000022947","K00084"]
["Metabolism","Lipid metabolism","Biosynthesis of unsaturated fatty acids",1,22,0.5910091,0.8364555,"ko01040","ENSMUSG00000025203","K00507"]
["Organismal Systems","Nervous system","Long-term potentiation",2,51,0.6081469,0.85140566,"ko04720","ENSMUSG00000020431;ENSMUSG00000042644","K08041+K04960"]
["Organismal Systems","Endocrine system","Prolactin signaling pathway",2,51,0.6081469,0.85140566,"ko04917","ENSMUSG00000070348;ENSMUSG00000053137","K04503+K04441"]
["Human Diseases","Cancers","Colorectal cancer",3,79,0.6142061,0.85145702,"ko05210","ENSMUSG00000070348;ENSMUSG00000024521;ENSMUSG00000021453","K04503+K10131+K04402"]
["Organismal Systems","Immune system","Th1 and Th2 cell differentiation",2,52,0.6188083,0.85145702,"ko04658","ENSMUSG00000003436;ENSMUSG00000053137","K06051+K04441"]
["Human Diseases","Infectious diseases","Amoebiasis",2,52,0.6188083,0.85145702,"ko05146","ENSMUSG00000020431;ENSMUSG00000016529","K08041+K05443"]
["Human Diseases","Infectious diseases","Hepatitis B",4,107,0.6213335,0.85145702,"ko05161","ENSMUSG00000070348;ENSMUSG00000032508;ENSMUSG00000027793;ENSMUSG00000017737","K04503+K04729+K06627+K01403"]
["Human Diseases","Infectious diseases","Salmonella infection",2,53,0.6292467,0.85776261,"ko05132","ENSMUSG00000053137;ENSMUSG00000032508","K04441+K04729"]
["Metabolism","Metabolism of cofactors and vitamins","Porphyrin and chlorophyll metabolism",1,25,0.6380734,0.86073443,"ko00860","ENSMUSG00000054545","K00699"]
["Environmental Information Processing","Membrane transport","ABC transporters",1,25,0.6380734,0.86073443,"ko02010","ENSMUSG00000020620","K05650"]
["Environmental Information Processing","Signal transduction","Wnt signaling pathway",4,110,0.643182,0.86223545,"ko04310","ENSMUSG00000070348;ENSMUSG00000001494;ENSMUSG00000030170;ENSMUSG00000012282","K04503+K16834+K00444+K00714"]
["Organismal Systems","Circulatory system","Cardiac muscle contraction",2,55,0.6494578,0.86223545,"ko04260","ENSMUSG00000059741;ENSMUSG00000035458","K12749+K12044"]
["Metabolism","Carbohydrate metabolism","Glyoxylate and dicarboxylate metabolism",1,26,0.6525318,0.86223545,"ko00630","ENSMUSG00000035637","K00049"]
["Organismal Systems","Digestive system","Mineral absorption",1,26,0.6525318,0.86223545,"ko04978","ENSMUSG00000031765","K14739"]
["Environmental Information Processing","Signal transduction","Jak-STAT signaling pathway",3,84,0.6558316,0.86223545,"ko04630","ENSMUSG00000070348;ENSMUSG00000020007;ENSMUSG00000016529","K04503+K05136+K05443"]
["Metabolism","Lipid metabolism","Ether lipid metabolism",1,27,0.6664156,0.8630082,"ko00565","ENSMUSG00000052160","K16860"]
["Genetic Information Processing","Folding, sorting and degradation","Protein export",1,27,0.6664156,0.8630082,"ko03060","ENSMUSG00000026864","K09490"]
["Human Diseases","Cancers","Chemical carcinogenesis",1,27,0.6664156,0.8630082,"ko05204","ENSMUSG00000054545","K00699"]
["Organismal Systems","Endocrine system","Insulin signaling pathway",4,114,0.6710132,0.8646389,"ko04910","ENSMUSG00000030815;ENSMUSG00000018566;ENSMUSG00000025006;ENSMUSG00000005057","K00871+K07191+K06086+K07193"]
["Metabolism","Carbohydrate metabolism","Propanoate metabolism",1,28,0.6797475,0.87155744,"ko00640","ENSMUSG00000063229","K00016"]
["Organismal Systems","Immune system","Natural killer cell mediated cytotoxicity",2,59,0.6872563,0.87684424,"ko04650","ENSMUSG00000021457;ENSMUSG00000067212","K05855+K06751"]
["Organismal Systems","Sensory system","Olfactory transduction",1,29,0.6925493,0.87701253,"ko04740","ENSMUSG00000042249","K00910"]
["Cellular Processes","Transport and catabolism","Phagosome",3,89,0.6941605,0.87701253,"ko04145","ENSMUSG00000003814;ENSMUSG00000001473;ENSMUSG00000067212","K08057+K07375+K06751"]
["Human Diseases","Cancers","Glioma",2,61,0.7048741,0.8862252,"ko05214","ENSMUSG00000070348;ENSMUSG00000021453","K04503+K04402"]
["Cellular Processes","Cell growth and death","Oocyte meiosis",3,93,0.7224558,0.89275521,"ko04114","ENSMUSG00000020431;ENSMUSG00000042644;ENSMUSG00000021536","K08041+K04960+K08042"]
["Organismal Systems","Excretory system","Endocrine and other factor-regulated calcium reabsorption",1,32,0.72798,0.89275521,"ko04961","ENSMUSG00000040265","K01528"]
["Human Diseases","Substance dependence","Cocaine addiction",1,32,0.72798,0.89275521,"ko05030","ENSMUSG00000032259","K04145"]
["Environmental Information Processing","Signal transduction","Hippo signaling pathway",4,123,0.7280788,0.89275521,"ko04390","ENSMUSG00000070348;ENSMUSG00000000303;ENSMUSG00000030170;ENSMUSG00000012282","K04503+K05689+K00444+K00714"]
["Human Diseases","Cancers","MicroRNAs in cancer",4,124,0.7339431,0.89275521,"ko05206","ENSMUSG00000020108;ENSMUSG00000070348;ENSMUSG00000054252;ENSMUSG00000017737","K08270+K04503+K05094+K01403"]
["Human Diseases","Drug resistance","EGFR tyrosine kinase inhibitor resistance",2,65,0.7376433,0.89275521,"ko01521","ENSMUSG00000030849;ENSMUSG00000054252","K05093+K05094"]
["Cellular Processes","Cellular community - eukaryotes","Adherens junction",2,65,0.7376433,0.89275521,"ko04520","ENSMUSG00000000303;ENSMUSG00000025006","K05689+K06086"]
["Human Diseases","Infectious diseases","Bacterial invasion of epithelial cells",2,65,0.7376433,0.89275521,"ko05100","ENSMUSG00000000303;ENSMUSG00000040265","K05689+K01528"]
["Human Diseases","Substance dependence","Alcoholism",4,126,0.7453881,0.89793264,"ko05034","ENSMUSG00000032259;ENSMUSG00000038811;ENSMUSG00000062727;ENSMUSG00000114279","K04145+K04549+K11252+K11252"]
["Metabolism","Amino acid metabolism","Arginine and proline metabolism",1,35,0.7593471,0.89920212,"ko00330","ENSMUSG00000019916","K00472"]
["Genetic Information Processing","Replication and repair","Base excision repair",1,35,0.7593471,0.89920212,"ko03410","ENSMUSG00000035121","K10568"]
["Environmental Information Processing","Signal transduction","TGF-beta signaling pathway",2,69,0.7672756,0.89920212,"ko04350","ENSMUSG00000066652;ENSMUSG00000023047","K04668+K04672"]
["Human Diseases","Cancers","Pancreatic cancer",2,69,0.7672756,0.89920212,"ko05212","ENSMUSG00000070348;ENSMUSG00000021453","K04503+K04402"]
["Organismal Systems","Excretory system","Vasopressin-regulated water reabsorption",1,36,0.7689815,0.89920212,"ko04962","ENSMUSG00000028435","K09876"]
["Organismal Systems","Nervous system","Neurotrophin signaling pathway",3,101,0.7729086,0.89920212,"ko04722","ENSMUSG00000005057;ENSMUSG00000053137;ENSMUSG00000109061","K07193+K04441+K04431"]
["Cellular Processes","Transport and catabolism","Peroxisome",2,70,0.7742165,0.89920212,"ko04146","ENSMUSG00000020333;ENSMUSG00000018796","K01897+K01897"]
["Organismal Systems","Immune system","Leukocyte transendothelial migration",2,70,0.7742165,0.89920212,"ko04670","ENSMUSG00000053137;ENSMUSG00000017737","K04441+K01403"]
["Metabolism","Amino acid metabolism","Cysteine and methionine metabolism",1,37,0.7782322,0.89983098,"ko00270","ENSMUSG00000063229","K00016"]
["Human Diseases","Cancers","Chronic myeloid leukemia",2,72,0.7875606,0.90656976,"ko05220","ENSMUSG00000070348;ENSMUSG00000021453","K04503+K04402"]
["Genetic Information Processing","Replication and repair","Homologous recombination",1,39,0.7956426,0.90780367,"ko03440","ENSMUSG00000030166","K10873"]
["Organismal Systems","Immune system","RIG-I-like receptor signaling pathway",1,39,0.7956426,0.90780367,"ko04622","ENSMUSG00000053137","K04441"]
["Human Diseases","Neurodegenerative diseases","Amyotrophic lateral sclerosis (ALS)",1,40,0.803831,0.9119079,"ko05014","ENSMUSG00000053137","K04441"]
["Organismal Systems","Aging","Longevity regulating pathway - mammal",2,75,0.8062815,0.9119079,"ko04211","ENSMUSG00000020431;ENSMUSG00000021536","K08041+K08042"]
["Metabolism","Metabolism of other amino acids","Glutathione metabolism",1,41,0.811693,0.9140369,"ko00480","ENSMUSG00000020649","K10808"]
["Human Diseases","Cancers","Choline metabolism in cancer",2,77,0.8179376,0.91708155,"ko05231","ENSMUSG00000028360;ENSMUSG00000034731","K15377+K00901"]
["Human Diseases","Cancers","Hepatocellular carcinoma",4,142,0.8238286,0.91871524,"ko05225","ENSMUSG00000070348;ENSMUSG00000021453;ENSMUSG00000030170;ENSMUSG00000012282","K04503+K04402+K00444+K00714"]
["Metabolism","Amino acid metabolism","Valine, leucine and isoleucine degradation",1,43,0.826489,0.91871524,"ko00280","ENSMUSG00000027875","K01641"]
["Genetic Information Processing","Translation","Aminoacyl-tRNA biosynthesis",1,44,0.8334474,0.92249093,"ko00970","ENSMUSG00000004233","K01867"]
["Environmental Information Processing","Signal transduction","VEGF signaling pathway",1,45,0.8401281,0.92592842,"ko04370","ENSMUSG00000053137","K04441"]
["Human Diseases","Cardiovascular diseases","Arrhythmogenic right ventricular cardiomyopathy (ARVC)",1,46,0.8465423,0.92602539,"ko05412","ENSMUSG00000034664","K06476"]
["Cellular Processes","Cell growth and death","Cell cycle",3,117,0.851411,0.92602539,"ko04110","ENSMUSG00000070348;ENSMUSG00000021453;ENSMUSG00000027793","K04503+K04402+K06627"]
["Human Diseases","Substance dependence","Amphetamine addiction",1,47,0.8527005,0.92602539,"ko05031","ENSMUSG00000022602","K15867"]
["Metabolism","Nucleotide metabolism","Pyrimidine metabolism",2,85,0.8585415,0.92602539,"ko00240","ENSMUSG00000020649;ENSMUSG00000025574","K10808+K00857"]
["Cellular Processes","Transport and catabolism","Autophagy - animal",3,120,0.8631872,0.92602539,"ko04140","ENSMUSG00000078566;ENSMUSG00000020108;ENSMUSG00000038387","K15464+K08270+K07829"]
["Cellular Processes","Cellular community - eukaryotes","Tight junction",3,120,0.8631872,0.92602539,"ko04530","ENSMUSG00000020733;ENSMUSG00000070348;ENSMUSG00000109061","K13365+K04503+K04431"]
["Metabolism","Global and overview maps","Metabolic pathways",32,941,0.8652438,0.92602539,"ko01100","ENSMUSG00000020649;ENSMUSG00000063229;ENSMUSG00000032294;ENSMUSG00000040434;ENSMUSG00000020277;ENSMUSG00000052102;ENSMUSG00000017390;ENSMUSG00000029314;ENSMUSG00000029171;ENSMUSG00000025574;ENSMUSG00000026447;ENSMUSG00000015806;ENSMUSG00000019916;ENSMUSG00000035637;ENSMUSG00000052160;ENSMUSG00000070644;ENSMUSG00000020333;ENSMUSG00000018796;ENSMUSG00000030621;ENSMUSG00000010660;ENSMUSG00000034744;ENSMUSG00000006731;ENSMUSG00000022947;ENSMUSG00000026817;ENSMUSG00000027875;ENSMUSG00000033540;ENSMUSG00000032323;ENSMUSG00000000673;ENSMUSG00000040280;ENSMUSG00000046854;ENSMUSG00000054545;ENSMUSG00000034731","K10808+K00016+K00873+K09668+K00850+K02564+K01623+K13506+K15779+K00857+K00923+K00357+K00472+K00049+K16860+K00894+K01897+K01897+K00029+K05857+K00884+K00725+K00084+K00939+K01641+K01217+K00498+K00452+K03948+K13712+K00699+K00901"]
["Organismal Systems","Immune system","B cell receptor signaling pathway",1,51,0.8749704,0.93258162,"ko04662","ENSMUSG00000021457","K05855"]
["Metabolism","Amino acid metabolism","Lysine degradation",1,54,0.8894446,0.94412357,"ko00310","ENSMUSG00000032374","K13645"]
["Human Diseases","Drug resistance","Platinum drug resistance",1,62,0.9203987,0.97299291,"ko01524","ENSMUSG00000024521","K10131"]
["Cellular Processes","Cellular community - eukaryotes","Focal adhesion",3,143,0.9293037,0.97841325,"ko04510","ENSMUSG00000070348;ENSMUSG00000034664;ENSMUSG00000027570","K04503+K06476+K08131"]
["Environmental Information Processing","Signal transduction","ErbB signaling pathway",1,71,0.94503,0.98678847,"ko04012","ENSMUSG00000109061","K04431"]
["Human Diseases","Infectious diseases","Herpes simplex infection",2,117,0.9511124,0.98678847,"ko05168","ENSMUSG00000067212;ENSMUSG00000032508","K06751+K04729"]
["Genetic Information Processing","Folding, sorting and degradation","RNA degradation",1,75,0.9533814,0.98678847,"ko03018","ENSMUSG00000020277","K00850"]
["Metabolism","Energy metabolism","Oxidative phosphorylation",2,119,0.9543588,0.98678847,"ko00190","ENSMUSG00000030946;ENSMUSG00000040280","K11725+K03948"]
["Human Diseases","Endocrine and metabolic diseases","Non-alcoholic fatty liver disease (NAFLD)",2,127,0.9654055,0.98678847,"ko04932","ENSMUSG00000025408;ENSMUSG00000040280","K04452+K03948"]
["Human Diseases","Infectious diseases","Hepatitis C",1,83,0.9664854,0.98678847,"ko05160","ENSMUSG00000053137","K04441"]
["Genetic Information Processing","Transcription","Spliceosome",2,128,0.9665915,0.98678847,"ko03040","ENSMUSG00000015656;ENSMUSG00000090877","K03283+K03283"]
["Human Diseases","Neurodegenerative diseases","Parkinson disease",2,129,0.9677385,0.98678847,"ko05012","ENSMUSG00000032259;ENSMUSG00000040280","K04145+K03948"]
["Environmental Information Processing","Signal transduction","Sphingolipid signaling pathway",1,95,0.9795935,0.99495967,"ko04071","ENSMUSG00000053137","K04441"]
["Human Diseases","Neurodegenerative diseases","Alzheimer disease",2,150,0.9846825,0.99621851,"ko05010","ENSMUSG00000042644;ENSMUSG00000040280","K04960+K03948"]
["Human Diseases","Neurodegenerative diseases","Huntington disease",2,158,0.9885257,0.99621851,"ko05016","ENSMUSG00000006930;ENSMUSG00000040280","K04647+K03948"]
["Genetic Information Processing","Folding, sorting and degradation","Ubiquitin mediated proteolysis",1,129,0.9950324,0.9977551,"ko04120","ENSMUSG00000041556","K10099"]
["Genetic Information Processing","Translation","RNA transport",1,148,0.9977551,0.9977551,"ko03013","ENSMUSG00000027939","K14314"]