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[null,"ID","Gene Name","Species","# of enriched GO biological processes for common ADHD/dyslexia network","# of enriched GO biological processes for gentic regulatory ADHD/dyslexia network","Average of columns E and F","Sum of columns E and F","Enriched GO biological processes for common ADHD/dyslexia network","Enriched GO biological processes for gentic regulatory ADHD/dyslexia network"]
[1,"TNF","tumor necrosis factor(TNF)","Homo sapiens",122,122,122,244,"GO:0000060~protein import into nucleus, translocation,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000165~MAPK cascade,GO:0000185~activation of MAPKKK activity,GO:0000187~activation of MAPK activity,GO:0001819~positive regulation of cytokine production,GO:0001934~positive regulation of protein phosphorylation,GO:0002439~chronic inflammatory response to antigenic stimulus,GO:0002740~negative regulation of cytokine secretion involved in immune response,GO:0002876~positive regulation of chronic inflammatory response to antigenic stimulus,GO:0002925~positive regulation of humoral immune response mediated by circulating immunoglobulin,GO:0006006~glucose metabolic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0006959~humoral immune response,GO:0007249~I-kappaB kinase/NF-kappaB signaling,GO:0007254~JNK cascade,GO:0008625~extrinsic apoptotic signaling pathway via death domain receptors,GO:0008630~intrinsic apoptotic signaling pathway in response to DNA damage,GO:0009615~response to virus,GO:0009651~response to salt stress,GO:0010628~positive regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0010693~negative regulation of alkaline phosphatase activity,GO:0010803~regulation of tumor necrosis factor-mediated signaling pathway,GO:0010888~negative regulation of lipid storage,GO:0030198~extracellular matrix organization,GO:0030316~osteoclast differentiation,GO:0030730~sequestering of triglyceride,GO:0030866~cortical actin cytoskeleton organization,GO:0031334~positive regulation of protein complex assembly,GO:0031622~positive regulation of fever generation,GO:0031663~lipopolysaccharide-mediated signaling pathway,GO:0032715~negative regulation of interleukin-6 production,GO:0032722~positive regulation of chemokine production,GO:0032729~positive regulation of interferon-gamma production,GO:0032755~positive regulation of interleukin-6 production,GO:0032757~positive regulation of interleukin-8 production,GO:0032800~receptor biosynthetic process,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0033209~tumor necrosis factor-mediated signaling pathway,GO:0034116~positive regulation of heterotypic cell-cell adhesion,GO:0035509~negative regulation of myosin-light-chain-phosphatase activity,GO:0042127~regulation of cell proliferation,GO:0042346~positive regulation of NF-kappaB import into nucleus,GO:0043065~positive regulation of apoptotic process,GO:0043068~positive regulation of programmed cell death,GO:0043122~regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043242~negative regulation of protein complex disassembly,GO:0043243~positive regulation of protein complex disassembly,GO:0043280~positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043406~positive regulation of MAP kinase activity,GO:0043491~protein kinase B signaling,GO:0043507~positive regulation of JUN kinase activity,GO:0044130~negative regulation of growth of symbiont in host,GO:0045071~negative regulation of viral genome replication,GO:0045080~positive regulation of chemokine biosynthetic process,GO:0045123~cellular extravasation,GO:0045416~positive regulation of interleukin-8 biosynthetic process,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045599~negative regulation of fat cell differentiation,GO:0045662~negative regulation of myoblast differentiation,GO:0045668~negative regulation of osteoblast differentiation,GO:0045670~regulation of osteoclast differentiation,GO:0045672~positive regulation of osteoclast differentiation,GO:0045785~positive regulation of cell adhesion,GO:0045860~positive regulation of protein kinase activity,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0045994~positive regulation of translational initiation by iron,GO:0046325~negative regulation of glucose import,GO:0046330~positive regulation of JNK cascade,GO:0048566~embryonic digestive tract development,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050715~positive regulation of cytokine secretion,GO:0050766~positive regulation of phagocytosis,GO:0050796~regulation of insulin secretion,GO:0050830~defense response to Gram-positive bacterium,GO:0050901~leukocyte tethering or rolling,GO:0050995~negative regulation of lipid catabolic process,GO:0051023~regulation of immunoglobulin secretion,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051222~positive regulation of protein transport,GO:0051384~response to glucocorticoid,GO:0051533~positive regulation of NFAT protein import into nucleus,GO:0051798~positive regulation of hair follicle development,GO:0051897~positive regulation of protein kinase B signaling,GO:0060557~positive regulation of vitamin D biosynthetic process,GO:0060559~positive regulation of calcidiol 1-monooxygenase activity,GO:0060664~epithelial cell proliferation involved in salivary gland morphogenesis,GO:0060693~regulation of branching involved in salivary gland morphogenesis,GO:0061048~negative regulation of branching involved in lung morphogenesis,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071222~cellular response to lipopolysaccharide,GO:0071230~cellular response to amino acid stimulus,GO:0071316~cellular response to nicotine,GO:0071407~cellular response to organic cyclic compound,GO:0071550~death-inducing signaling complex assembly,GO:0071677~positive regulation of mononuclear cell migration,GO:0071803~positive regulation of podosome assembly,GO:0072659~protein localization to plasma membrane,GO:0090002~establishment of protein localization to plasma membrane,GO:0097191~extrinsic apoptotic signaling pathway,GO:0097527~necroptotic signaling pathway,GO:1901224~positive regulation of NIK/NF-kappaB signaling,GO:1901671~positive regulation of superoxide dismutase activity,GO:1903140~regulation of establishment of endothelial barrier,GO:1903347~negative regulation of bicellular tight junction assembly,GO:1904996~positive regulation of leukocyte adhesion to vascular endothelial cell,GO:1904999~positive regulation of leukocyte adhesion to arterial endothelial cell,GO:2000010~positive regulation of protein localization to cell surface,GO:2000304~positive regulation of ceramide biosynthetic process,GO:2000334~positive regulation of blood microparticle formation,GO:2000343~positive regulation of chemokine (C-X-C motif) ligand 2 production,GO:2000377~regulation of reactive oxygen species metabolic process,GO:2001240~negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,","GO:0000060~protein import into nucleus, translocation,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000165~MAPK cascade,GO:0000185~activation of MAPKKK activity,GO:0000187~activation of MAPK activity,GO:0001819~positive regulation of cytokine production,GO:0001934~positive regulation of protein phosphorylation,GO:0002439~chronic inflammatory response to antigenic stimulus,GO:0002740~negative regulation of cytokine secretion involved in immune response,GO:0002876~positive regulation of chronic inflammatory response to antigenic stimulus,GO:0002925~positive regulation of humoral immune response mediated by circulating immunoglobulin,GO:0006006~glucose metabolic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0006959~humoral immune response,GO:0007249~I-kappaB kinase/NF-kappaB signaling,GO:0007254~JNK cascade,GO:0008625~extrinsic apoptotic signaling pathway via death domain receptors,GO:0008630~intrinsic apoptotic signaling pathway in response to DNA damage,GO:0009615~response to virus,GO:0009651~response to salt stress,GO:0010628~positive regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0010693~negative regulation of alkaline phosphatase activity,GO:0010803~regulation of tumor necrosis factor-mediated signaling pathway,GO:0010888~negative regulation of lipid storage,GO:0030198~extracellular matrix organization,GO:0030316~osteoclast differentiation,GO:0030730~sequestering of triglyceride,GO:0030866~cortical actin cytoskeleton organization,GO:0031334~positive regulation of protein complex assembly,GO:0031622~positive regulation of fever generation,GO:0031663~lipopolysaccharide-mediated signaling pathway,GO:0032715~negative regulation of interleukin-6 production,GO:0032722~positive regulation of chemokine production,GO:0032729~positive regulation of interferon-gamma production,GO:0032755~positive regulation of interleukin-6 production,GO:0032757~positive regulation of interleukin-8 production,GO:0032800~receptor biosynthetic process,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0033209~tumor necrosis factor-mediated signaling pathway,GO:0034116~positive regulation of heterotypic cell-cell adhesion,GO:0035509~negative regulation of myosin-light-chain-phosphatase activity,GO:0042127~regulation of cell proliferation,GO:0042346~positive regulation of NF-kappaB import into nucleus,GO:0043065~positive regulation of apoptotic process,GO:0043068~positive regulation of programmed cell death,GO:0043122~regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043242~negative regulation of protein complex disassembly,GO:0043243~positive regulation of protein complex disassembly,GO:0043280~positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043406~positive regulation of MAP kinase activity,GO:0043491~protein kinase B signaling,GO:0043507~positive regulation of JUN kinase activity,GO:0044130~negative regulation of growth of symbiont in host,GO:0045071~negative regulation of viral genome replication,GO:0045080~positive regulation of chemokine biosynthetic process,GO:0045123~cellular extravasation,GO:0045416~positive regulation of interleukin-8 biosynthetic process,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045599~negative regulation of fat cell differentiation,GO:0045662~negative regulation of myoblast differentiation,GO:0045668~negative regulation of osteoblast differentiation,GO:0045670~regulation of osteoclast differentiation,GO:0045672~positive regulation of osteoclast differentiation,GO:0045785~positive regulation of cell adhesion,GO:0045860~positive regulation of protein kinase activity,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0045994~positive regulation of translational initiation by iron,GO:0046325~negative regulation of glucose import,GO:0046330~positive regulation of JNK cascade,GO:0048566~embryonic digestive tract development,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050715~positive regulation of cytokine secretion,GO:0050766~positive regulation of phagocytosis,GO:0050796~regulation of insulin secretion,GO:0050830~defense response to Gram-positive bacterium,GO:0050901~leukocyte tethering or rolling,GO:0050995~negative regulation of lipid catabolic process,GO:0051023~regulation of immunoglobulin secretion,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051222~positive regulation of protein transport,GO:0051384~response to glucocorticoid,GO:0051533~positive regulation of NFAT protein import into nucleus,GO:0051798~positive regulation of hair follicle development,GO:0051897~positive regulation of protein kinase B signaling,GO:0060557~positive regulation of vitamin D biosynthetic process,GO:0060559~positive regulation of calcidiol 1-monooxygenase activity,GO:0060664~epithelial cell proliferation involved in salivary gland morphogenesis,GO:0060693~regulation of branching involved in salivary gland morphogenesis,GO:0061048~negative regulation of branching involved in lung morphogenesis,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071222~cellular response to lipopolysaccharide,GO:0071230~cellular response to amino acid stimulus,GO:0071316~cellular response to nicotine,GO:0071407~cellular response to organic cyclic compound,GO:0071550~death-inducing signaling complex assembly,GO:0071677~positive regulation of mononuclear cell migration,GO:0071803~positive regulation of podosome assembly,GO:0072659~protein localization to plasma membrane,GO:0090002~establishment of protein localization to plasma membrane,GO:0097191~extrinsic apoptotic signaling pathway,GO:0097527~necroptotic signaling pathway,GO:1901224~positive regulation of NIK/NF-kappaB signaling,GO:1901671~positive regulation of superoxide dismutase activity,GO:1903140~regulation of establishment of endothelial barrier,GO:1903347~negative regulation of bicellular tight junction assembly,GO:1904996~positive regulation of leukocyte adhesion to vascular endothelial cell,GO:1904999~positive regulation of leukocyte adhesion to arterial endothelial cell,GO:2000010~positive regulation of protein localization to cell surface,GO:2000304~positive regulation of ceramide biosynthetic process,GO:2000334~positive regulation of blood microparticle formation,GO:2000343~positive regulation of chemokine (C-X-C motif) ligand 2 production,GO:2000377~regulation of reactive oxygen species metabolic process,GO:2001240~negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,"]
[2,"IL6","interleukin 6(IL6)","Homo sapiens",109,109,109,218,"GO:0001781~neutrophil apoptotic process,GO:0001878~response to yeast,GO:0002384~hepatic immune response,GO:0002446~neutrophil mediated immunity,GO:0002526~acute inflammatory response,GO:0002548~monocyte chemotaxis,GO:0002675~positive regulation of acute inflammatory response,GO:0002690~positive regulation of leukocyte chemotaxis,GO:0006469~negative regulation of protein kinase activity,GO:0006953~acute-phase response,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0006959~humoral immune response,GO:0007568~aging,GO:0008284~positive regulation of cell proliferation,GO:0008285~negative regulation of cell proliferation,GO:0008360~regulation of cell shape,GO:0009408~response to heat,GO:0009409~response to cold,GO:0010574~regulation of vascular endothelial growth factor production,GO:0010628~positive regulation of gene expression,GO:0010888~negative regulation of lipid storage,GO:0010976~positive regulation of neuron projection development,GO:0010996~response to auditory stimulus,GO:0016049~cell growth,GO:0019221~cytokine-mediated signaling pathway,GO:0030168~platelet activation,GO:0031000~response to caffeine,GO:0031018~endocrine pancreas development,GO:0031175~neuron projection development,GO:0031669~cellular response to nutrient levels,GO:0032494~response to peptidoglycan,GO:0032722~positive regulation of chemokine production,GO:0032755~positive regulation of interleukin-6 production,GO:0032868~response to insulin,GO:0032966~negative regulation of collagen biosynthetic process,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0033160~positive regulation of protein import into nucleus, translocation,GO:0035729~cellular response to hepatocyte growth factor stimulus,GO:0042060~wound healing,GO:0042102~positive regulation of T cell proliferation,GO:0042493~response to drug,GO:0042517~positive regulation of tyrosine phosphorylation of Stat3 protein,GO:0042593~glucose homeostasis,GO:0042832~defense response to protozoan,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043200~response to amino acid,GO:0043410~positive regulation of MAPK cascade,GO:0045079~negative regulation of chemokine biosynthetic process,GO:0045188~regulation of circadian sleep/wake cycle, non-REM sleep,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045454~cell redox homeostasis,GO:0045599~negative regulation of fat cell differentiation,GO:0045630~positive regulation of T-helper 2 cell differentiation,GO:0045669~positive regulation of osteoblast differentiation,GO:0045721~negative regulation of gluconeogenesis,GO:0045727~positive regulation of translation,GO:0045740~positive regulation of DNA replication,GO:0045765~regulation of angiogenesis,GO:0045779~negative regulation of bone resorption,GO:0045837~negative regulation of membrane potential,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046427~positive regulation of JAK-STAT cascade,GO:0046677~response to antibiotic,GO:0046716~muscle cell cellular homeostasis,GO:0046849~bone remodeling,GO:0046888~negative regulation of hormone secretion,GO:0048635~negative regulation of muscle organ development,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050679~positive regulation of epithelial cell proliferation,GO:0050710~negative regulation of cytokine secretion,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0050829~defense response to Gram-negative bacterium,GO:0050830~defense response to Gram-positive bacterium,GO:0050871~positive regulation of B cell activation,GO:0051024~positive regulation of immunoglobulin secretion,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051384~response to glucocorticoid,GO:0051592~response to calcium ion,GO:0051602~response to electrical stimulus,GO:0051607~defense response to virus,GO:0051897~positive regulation of protein kinase B signaling,GO:0051971~positive regulation of transmission of nerve impulse,GO:0060445~branching involved in salivary gland morphogenesis,GO:0060664~epithelial cell proliferation involved in salivary gland morphogenesis,GO:0070091~glucagon secretion,GO:0070102~interleukin-6-mediated signaling pathway,GO:0070301~cellular response to hydrogen peroxide,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071222~cellular response to lipopolysaccharide,GO:0071347~cellular response to interleukin-1,GO:0071356~cellular response to tumor necrosis factor,GO:0071392~cellular response to estradiol stimulus,GO:0071549~cellular response to dexamethasone stimulus,GO:0071864~positive regulation of cell proliferation in bone marrow,GO:0072540~T-helper 17 cell lineage commitment,GO:1901215~negative regulation of neuron death,GO:1990646~cellular response to prolactin,GO:2000366~positive regulation of STAT protein import into nucleus,GO:2000553~positive regulation of T-helper 2 cell cytokine production,GO:2000660~negative regulation of interleukin-1-mediated signaling pathway,GO:2000676~positive regulation of type B pancreatic cell apoptotic process,","GO:0001781~neutrophil apoptotic process,GO:0001878~response to yeast,GO:0002384~hepatic immune response,GO:0002446~neutrophil mediated immunity,GO:0002526~acute inflammatory response,GO:0002548~monocyte chemotaxis,GO:0002675~positive regulation of acute inflammatory response,GO:0002690~positive regulation of leukocyte chemotaxis,GO:0006469~negative regulation of protein kinase activity,GO:0006953~acute-phase response,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0006959~humoral immune response,GO:0007568~aging,GO:0008284~positive regulation of cell proliferation,GO:0008285~negative regulation of cell proliferation,GO:0008360~regulation of cell shape,GO:0009408~response to heat,GO:0009409~response to cold,GO:0010574~regulation of vascular endothelial growth factor production,GO:0010628~positive regulation of gene expression,GO:0010888~negative regulation of lipid storage,GO:0010976~positive regulation of neuron projection development,GO:0010996~response to auditory stimulus,GO:0016049~cell growth,GO:0019221~cytokine-mediated signaling pathway,GO:0030168~platelet activation,GO:0031000~response to caffeine,GO:0031018~endocrine pancreas development,GO:0031175~neuron projection development,GO:0031669~cellular response to nutrient levels,GO:0032494~response to peptidoglycan,GO:0032722~positive regulation of chemokine production,GO:0032755~positive regulation of interleukin-6 production,GO:0032868~response to insulin,GO:0032966~negative regulation of collagen biosynthetic process,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0033160~positive regulation of protein import into nucleus, translocation,GO:0035729~cellular response to hepatocyte growth factor stimulus,GO:0042060~wound healing,GO:0042102~positive regulation of T cell proliferation,GO:0042493~response to drug,GO:0042517~positive regulation of tyrosine phosphorylation of Stat3 protein,GO:0042593~glucose homeostasis,GO:0042832~defense response to protozoan,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043200~response to amino acid,GO:0043410~positive regulation of MAPK cascade,GO:0045079~negative regulation of chemokine biosynthetic process,GO:0045188~regulation of circadian sleep/wake cycle, non-REM sleep,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045454~cell redox homeostasis,GO:0045599~negative regulation of fat cell differentiation,GO:0045630~positive regulation of T-helper 2 cell differentiation,GO:0045669~positive regulation of osteoblast differentiation,GO:0045721~negative regulation of gluconeogenesis,GO:0045727~positive regulation of translation,GO:0045740~positive regulation of DNA replication,GO:0045765~regulation of angiogenesis,GO:0045779~negative regulation of bone resorption,GO:0045837~negative regulation of membrane potential,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046427~positive regulation of JAK-STAT cascade,GO:0046677~response to antibiotic,GO:0046716~muscle cell cellular homeostasis,GO:0046849~bone remodeling,GO:0046888~negative regulation of hormone secretion,GO:0048635~negative regulation of muscle organ development,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050679~positive regulation of epithelial cell proliferation,GO:0050710~negative regulation of cytokine secretion,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0050829~defense response to Gram-negative bacterium,GO:0050830~defense response to Gram-positive bacterium,GO:0050871~positive regulation of B cell activation,GO:0051024~positive regulation of immunoglobulin secretion,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051384~response to glucocorticoid,GO:0051592~response to calcium ion,GO:0051602~response to electrical stimulus,GO:0051607~defense response to virus,GO:0051897~positive regulation of protein kinase B signaling,GO:0051971~positive regulation of transmission of nerve impulse,GO:0060445~branching involved in salivary gland morphogenesis,GO:0060664~epithelial cell proliferation involved in salivary gland morphogenesis,GO:0070091~glucagon secretion,GO:0070102~interleukin-6-mediated signaling pathway,GO:0070301~cellular response to hydrogen peroxide,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071222~cellular response to lipopolysaccharide,GO:0071347~cellular response to interleukin-1,GO:0071356~cellular response to tumor necrosis factor,GO:0071392~cellular response to estradiol stimulus,GO:0071549~cellular response to dexamethasone stimulus,GO:0071864~positive regulation of cell proliferation in bone marrow,GO:0072540~T-helper 17 cell lineage commitment,GO:1901215~negative regulation of neuron death,GO:1990646~cellular response to prolactin,GO:2000366~positive regulation of STAT protein import into nucleus,GO:2000553~positive regulation of T-helper 2 cell cytokine production,GO:2000660~negative regulation of interleukin-1-mediated signaling pathway,GO:2000676~positive regulation of type B pancreatic cell apoptotic process,"]
[3,"DRD2","dopamine receptor D2(DRD2)","Homo sapiens",97,96,96.5,193,"GO:0001659~temperature homeostasis,GO:0001666~response to hypoxia,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0001976~neurological system process involved in regulation of systemic arterial blood pressure,GO:0002027~regulation of heart rate,GO:0002028~regulation of sodium ion transport,GO:0002031~G-protein coupled receptor internalization,GO:0002052~positive regulation of neuroblast proliferation,GO:0002092~positive regulation of receptor internalization,GO:0006874~cellular calcium ion homeostasis,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007270~neuron-neuron synaptic transmission,GO:0007409~axonogenesis,GO:0007416~synapse assembly,GO:0007608~sensory perception of smell,GO:0007616~long-term memory,GO:0007625~grooming behavior,GO:0007626~locomotory behavior,GO:0007628~adult walking behavior,GO:0007631~feeding behavior,GO:0008104~protein localization,GO:0008285~negative regulation of cell proliferation,GO:0008306~associative learning,GO:0008542~visual learning,GO:0009416~response to light stimulus,GO:0009636~response to toxic substance,GO:0010039~response to iron ion,GO:0014059~regulation of dopamine secretion,GO:0014854~response to inactivity,GO:0016055~Wnt signaling pathway,GO:0021756~striatum development,GO:0021769~orbitofrontal cortex development,GO:0021853~cerebral cortex GABAergic interneuron migration,GO:0021984~adenohypophysis development,GO:0030336~negative regulation of cell migration,GO:0030432~peristalsis,GO:0030814~regulation of cAMP metabolic process,GO:0031223~auditory behavior,GO:0032147~activation of protein kinase activity,GO:0032228~regulation of synaptic transmission, GABAergic,GO:0032467~positive regulation of cytokinesis,GO:0032922~circadian regulation of gene expression,GO:0033602~negative regulation of dopamine secretion,GO:0034776~response to histamine,GO:0035094~response to nicotine,GO:0035556~intracellular signal transduction,GO:0035810~positive regulation of urine volume,GO:0035815~positive regulation of renal sodium excretion,GO:0040018~positive regulation of multicellular organism growth,GO:0042220~response to cocaine,GO:0042321~negative regulation of circadian sleep/wake cycle, sleep,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0043266~regulation of potassium ion transport,GO:0043278~response to morphine,GO:0043473~pigmentation,GO:0043666~regulation of phosphoprotein phosphatase activity,GO:0045745~positive regulation of G-protein coupled receptor protein signaling pathway,GO:0045776~negative regulation of blood pressure,GO:0045824~negative regulation of innate immune response,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046488~phosphatidylinositol metabolic process,GO:0046676~negative regulation of insulin secretion,GO:0046717~acid secretion,GO:0048148~behavioral response to cocaine,GO:0048149~behavioral response to ethanol,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048678~response to axon injury,GO:0048755~branching morphogenesis of a nerve,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0051209~release of sequestered calcium ion into cytosol,GO:0051481~negative regulation of cytosolic calcium ion concentration,GO:0051482~positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051586~positive regulation of dopamine uptake involved in synaptic transmission,GO:0051823~regulation of synapse structural plasticity,GO:0051898~negative regulation of protein kinase B signaling,GO:0051967~negative regulation of synaptic transmission, glutamatergic,GO:0060124~positive regulation of growth hormone secretion,GO:0060134~prepulse inhibition,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060160~negative regulation of dopamine receptor signaling pathway,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071880~adenylate cyclase-activating adrenergic receptor signaling pathway,GO:0090325~regulation of locomotion involved in locomotory behavior,GO:0099565~chemical synaptic transmission, postsynaptic,GO:1900168~positive regulation of glial cell-derived neurotrophic factor secretion,GO:1900273~positive regulation of long-term synaptic potentiation,GO:1901386~negative regulation of voltage-gated calcium channel activity,","GO:0001659~temperature homeostasis,GO:0001666~response to hypoxia,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0001976~neurological system process involved in regulation of systemic arterial blood pressure,GO:0002027~regulation of heart rate,GO:0002028~regulation of sodium ion transport,GO:0002031~G-protein coupled receptor internalization,GO:0002052~positive regulation of neuroblast proliferation,GO:0002092~positive regulation of receptor internalization,GO:0006874~cellular calcium ion homeostasis,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007270~neuron-neuron synaptic transmission,GO:0007409~axonogenesis,GO:0007416~synapse assembly,GO:0007608~sensory perception of smell,GO:0007616~long-term memory,GO:0007625~grooming behavior,GO:0007626~locomotory behavior,GO:0007628~adult walking behavior,GO:0007631~feeding behavior,GO:0008104~protein localization,GO:0008285~negative regulation of cell proliferation,GO:0008306~associative learning,GO:0008542~visual learning,GO:0009416~response to light stimulus,GO:0009636~response to toxic substance,GO:0010039~response to iron ion,GO:0014059~regulation of dopamine secretion,GO:0014854~response to inactivity,GO:0016055~Wnt signaling pathway,GO:0021756~striatum development,GO:0021769~orbitofrontal cortex development,GO:0021853~cerebral cortex GABAergic interneuron migration,GO:0021984~adenohypophysis development,GO:0030336~negative regulation of cell migration,GO:0030432~peristalsis,GO:0030814~regulation of cAMP metabolic process,GO:0031223~auditory behavior,GO:0032147~activation of protein kinase activity,GO:0032228~regulation of synaptic transmission, GABAergic,GO:0032467~positive regulation of cytokinesis,GO:0032922~circadian regulation of gene expression,GO:0033602~negative regulation of dopamine secretion,GO:0034776~response to histamine,GO:0035094~response to nicotine,GO:0035556~intracellular signal transduction,GO:0035810~positive regulation of urine volume,GO:0035815~positive regulation of renal sodium excretion,GO:0040018~positive regulation of multicellular organism growth,GO:0042220~response to cocaine,GO:0042321~negative regulation of circadian sleep/wake cycle, sleep,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0043266~regulation of potassium ion transport,GO:0043278~response to morphine,GO:0043473~pigmentation,GO:0043666~regulation of phosphoprotein phosphatase activity,GO:0045745~positive regulation of G-protein coupled receptor protein signaling pathway,GO:0045776~negative regulation of blood pressure,GO:0045824~negative regulation of innate immune response,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046488~phosphatidylinositol metabolic process,GO:0046676~negative regulation of insulin secretion,GO:0046717~acid secretion,GO:0048148~behavioral response to cocaine,GO:0048149~behavioral response to ethanol,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048678~response to axon injury,GO:0048755~branching morphogenesis of a nerve,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0051209~release of sequestered calcium ion into cytosol,GO:0051481~negative regulation of cytosolic calcium ion concentration,GO:0051482~positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051586~positive regulation of dopamine uptake involved in synaptic transmission,GO:0051823~regulation of synapse structural plasticity,GO:0051898~negative regulation of protein kinase B signaling,GO:0051967~negative regulation of synaptic transmission, glutamatergic,GO:0060124~positive regulation of growth hormone secretion,GO:0060134~prepulse inhibition,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060160~negative regulation of dopamine receptor signaling pathway,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071880~adenylate cyclase-activating adrenergic receptor signaling pathway,GO:0090325~regulation of locomotion involved in locomotory behavior,GO:0099565~chemical synaptic transmission, postsynaptic,GO:1900168~positive regulation of glial cell-derived neurotrophic factor secretion,GO:1900273~positive regulation of long-term synaptic potentiation,GO:1901386~negative regulation of voltage-gated calcium channel activity,"]
[4,"APOE","apolipoprotein E(APOE)","Homo sapiens",88,88,88,176,"GO:0000302~response to reactive oxygen species,GO:0001523~retinoid metabolic process,GO:0001937~negative regulation of endothelial cell proliferation,GO:0002021~response to dietary excess,GO:0006641~triglyceride metabolic process,GO:0006707~cholesterol catabolic process,GO:0006869~lipid transport,GO:0006874~cellular calcium ion homeostasis,GO:0006898~receptor-mediated endocytosis,GO:0006979~response to oxidative stress,GO:0007010~cytoskeleton organization,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007263~nitric oxide mediated signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0008203~cholesterol metabolic process,GO:0010468~regulation of gene expression,GO:0010544~negative regulation of platelet activation,GO:0010873~positive regulation of cholesterol esterification,GO:0010875~positive regulation of cholesterol efflux,GO:0010877~lipid transport involved in lipid storage,GO:0015909~long-chain fatty acid transport,GO:0017038~protein import,GO:0019068~virion assembly,GO:0019433~triglyceride catabolic process,GO:0019934~cGMP-mediated signaling,GO:0030195~negative regulation of blood coagulation,GO:0030516~regulation of axon extension,GO:0030828~positive regulation of cGMP biosynthetic process,GO:0031102~neuron projection regeneration,GO:0032489~regulation of Cdc42 protein signal transduction,GO:0032805~positive regulation of low-density lipoprotein particle receptor catabolic process,GO:0033344~cholesterol efflux,GO:0033700~phospholipid efflux,GO:0034372~very-low-density lipoprotein particle remodeling,GO:0034374~low-density lipoprotein particle remodeling,GO:0034375~high-density lipoprotein particle remodeling,GO:0034380~high-density lipoprotein particle assembly,GO:0034382~chylomicron remnant clearance,GO:0034384~high-density lipoprotein particle clearance,GO:0034447~very-low-density lipoprotein particle clearance,GO:0042157~lipoprotein metabolic process,GO:0042158~lipoprotein biosynthetic process,GO:0042159~lipoprotein catabolic process,GO:0042311~vasodilation,GO:0042632~cholesterol homeostasis,GO:0043407~negative regulation of MAP kinase activity,GO:0043524~negative regulation of neuron apoptotic process,GO:0043537~negative regulation of blood vessel endothelial cell migration,GO:0043691~reverse cholesterol transport,GO:0044794~positive regulation by host of viral process,GO:0045541~negative regulation of cholesterol biosynthetic process,GO:0046889~positive regulation of lipid biosynthetic process,GO:0046907~intracellular transport,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048844~artery morphogenesis,GO:0050728~negative regulation of inflammatory response,GO:0051000~positive regulation of nitric-oxide synthase activity,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051055~negative regulation of lipid biosynthetic process,GO:0051651~maintenance of location in cell,GO:0055089~fatty acid homeostasis,GO:0060999~positive regulation of dendritic spine development,GO:0061000~negative regulation of dendritic spine development,GO:0070328~triglyceride homeostasis,GO:0090090~negative regulation of canonical Wnt signaling pathway,GO:0090370~negative regulation of cholesterol efflux,GO:0097113~AMPA glutamate receptor clustering,GO:0097114~NMDA glutamate receptor clustering,GO:0098869~cellular oxidant detoxification,GO:1900221~regulation of beta-amyloid clearance,GO:1901214~regulation of neuron death,GO:1901215~negative regulation of neuron death,GO:1901216~positive regulation of neuron death,GO:1901627~negative regulation of postsynaptic membrane organization,GO:1901628~positive regulation of postsynaptic membrane organization,GO:1901630~negative regulation of presynaptic membrane organization,GO:1901631~positive regulation of presynaptic membrane organization,GO:1902004~positive regulation of beta-amyloid formation,GO:1902430~negative regulation of beta-amyloid formation,GO:1902947~regulation of tau-protein kinase activity,GO:1902951~negative regulation of dendritic spine maintenance,GO:1902952~positive regulation of dendritic spine maintenance,GO:1902995~positive regulation of phospholipid efflux,GO:1902998~positive regulation of neurofibrillary tangle assembly,GO:1902999~negative regulation of phospholipid efflux,GO:1903001~negative regulation of lipid transport across blood brain barrier,GO:1903002~positive regulation of lipid transport across blood brain barrier,","GO:0000302~response to reactive oxygen species,GO:0001523~retinoid metabolic process,GO:0001937~negative regulation of endothelial cell proliferation,GO:0002021~response to dietary excess,GO:0006641~triglyceride metabolic process,GO:0006707~cholesterol catabolic process,GO:0006869~lipid transport,GO:0006874~cellular calcium ion homeostasis,GO:0006898~receptor-mediated endocytosis,GO:0006979~response to oxidative stress,GO:0007010~cytoskeleton organization,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007263~nitric oxide mediated signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0008203~cholesterol metabolic process,GO:0010468~regulation of gene expression,GO:0010544~negative regulation of platelet activation,GO:0010873~positive regulation of cholesterol esterification,GO:0010875~positive regulation of cholesterol efflux,GO:0010877~lipid transport involved in lipid storage,GO:0015909~long-chain fatty acid transport,GO:0017038~protein import,GO:0019068~virion assembly,GO:0019433~triglyceride catabolic process,GO:0019934~cGMP-mediated signaling,GO:0030195~negative regulation of blood coagulation,GO:0030516~regulation of axon extension,GO:0030828~positive regulation of cGMP biosynthetic process,GO:0031102~neuron projection regeneration,GO:0032489~regulation of Cdc42 protein signal transduction,GO:0032805~positive regulation of low-density lipoprotein particle receptor catabolic process,GO:0033344~cholesterol efflux,GO:0033700~phospholipid efflux,GO:0034372~very-low-density lipoprotein particle remodeling,GO:0034374~low-density lipoprotein particle remodeling,GO:0034375~high-density lipoprotein particle remodeling,GO:0034380~high-density lipoprotein particle assembly,GO:0034382~chylomicron remnant clearance,GO:0034384~high-density lipoprotein particle clearance,GO:0034447~very-low-density lipoprotein particle clearance,GO:0042157~lipoprotein metabolic process,GO:0042158~lipoprotein biosynthetic process,GO:0042159~lipoprotein catabolic process,GO:0042311~vasodilation,GO:0042632~cholesterol homeostasis,GO:0043407~negative regulation of MAP kinase activity,GO:0043524~negative regulation of neuron apoptotic process,GO:0043537~negative regulation of blood vessel endothelial cell migration,GO:0043691~reverse cholesterol transport,GO:0044794~positive regulation by host of viral process,GO:0045541~negative regulation of cholesterol biosynthetic process,GO:0046889~positive regulation of lipid biosynthetic process,GO:0046907~intracellular transport,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048844~artery morphogenesis,GO:0050728~negative regulation of inflammatory response,GO:0051000~positive regulation of nitric-oxide synthase activity,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051055~negative regulation of lipid biosynthetic process,GO:0051651~maintenance of location in cell,GO:0055089~fatty acid homeostasis,GO:0060999~positive regulation of dendritic spine development,GO:0061000~negative regulation of dendritic spine development,GO:0070328~triglyceride homeostasis,GO:0090090~negative regulation of canonical Wnt signaling pathway,GO:0090370~negative regulation of cholesterol efflux,GO:0097113~AMPA glutamate receptor clustering,GO:0097114~NMDA glutamate receptor clustering,GO:0098869~cellular oxidant detoxification,GO:1900221~regulation of beta-amyloid clearance,GO:1901214~regulation of neuron death,GO:1901215~negative regulation of neuron death,GO:1901216~positive regulation of neuron death,GO:1901627~negative regulation of postsynaptic membrane organization,GO:1901628~positive regulation of postsynaptic membrane organization,GO:1901630~negative regulation of presynaptic membrane organization,GO:1901631~positive regulation of presynaptic membrane organization,GO:1902004~positive regulation of beta-amyloid formation,GO:1902430~negative regulation of beta-amyloid formation,GO:1902947~regulation of tau-protein kinase activity,GO:1902951~negative regulation of dendritic spine maintenance,GO:1902952~positive regulation of dendritic spine maintenance,GO:1902995~positive regulation of phospholipid efflux,GO:1902998~positive regulation of neurofibrillary tangle assembly,GO:1902999~negative regulation of phospholipid efflux,GO:1903001~negative regulation of lipid transport across blood brain barrier,GO:1903002~positive regulation of lipid transport across blood brain barrier,"]
[5,"SNCA","synuclein alpha(SNCA)","Homo sapiens",72,72,72,144,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001774~microglial cell activation,GO:0001921~positive regulation of receptor recycling,GO:0001933~negative regulation of protein phosphorylation,GO:0001956~positive regulation of neurotransmitter secretion,GO:0006631~fatty acid metabolic process,GO:0006638~neutral lipid metabolic process,GO:0006644~phospholipid metabolic process,GO:0006915~apoptotic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0007006~mitochondrial membrane organization,GO:0007568~aging,GO:0008344~adult locomotory behavior,GO:0010040~response to iron(II) ion,GO:0010517~regulation of phospholipase activity,GO:0010642~negative regulation of platelet-derived growth factor receptor signaling pathway,GO:0014048~regulation of glutamate secretion,GO:0014059~regulation of dopamine secretion,GO:0031115~negative regulation of microtubule polymerization,GO:0031623~receptor internalization,GO:0031648~protein destabilization,GO:0032026~response to magnesium ion,GO:0032410~negative regulation of transporter activity,GO:0032496~response to lipopolysaccharide,GO:0032769~negative regulation of monooxygenase activity,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0034341~response to interferon-gamma,GO:0034599~cellular response to oxidative stress,GO:0035067~negative regulation of histone acetylation,GO:0040012~regulation of locomotion,GO:0042416~dopamine biosynthetic process,GO:0042493~response to drug,GO:0042775~mitochondrial ATP synthesis coupled electron transport,GO:0043030~regulation of macrophage activation,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043206~extracellular fibril organization,GO:0043524~negative regulation of neuron apoptotic process,GO:0044267~cellular protein metabolic process,GO:0044344~cellular response to fibroblast growth factor stimulus,GO:0045807~positive regulation of endocytosis,GO:0045920~negative regulation of exocytosis,GO:0045963~negative regulation of dopamine metabolic process,GO:0048148~behavioral response to cocaine,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048488~synaptic vesicle endocytosis,GO:0050808~synapse organization,GO:0050812~regulation of acyl-CoA biosynthetic process,GO:0051281~positive regulation of release of sequestered calcium ion into cytosol,GO:0051583~dopamine uptake involved in synaptic transmission,GO:0051585~negative regulation of dopamine uptake involved in synaptic transmission,GO:0051612~negative regulation of serotonin uptake,GO:0051622~negative regulation of norepinephrine uptake,GO:0055074~calcium ion homeostasis,GO:0055114~oxidation-reduction process,GO:0060079~excitatory postsynaptic potential,GO:0060291~long-term synaptic potentiation,GO:0060732~positive regulation of inositol phosphate biosynthetic process,GO:0070495~negative regulation of thrombin receptor signaling pathway,GO:0070555~response to interleukin-1,GO:0071280~cellular response to copper ion,GO:0071872~cellular response to epinephrine stimulus,GO:0071902~positive regulation of protein serine/threonine kinase activity,GO:1901215~negative regulation of neuron death,GO:1902957~negative regulation of mitochondrial electron transport, NADH to ubiquinone,GO:1903284~positive regulation of glutathione peroxidase activity,GO:1903285~positive regulation of hydrogen peroxide catabolic process,GO:1903421~regulation of synaptic vesicle recycling,GO:1903426~regulation of reactive oxygen species biosynthetic process,GO:1904715~negative regulation of chaperone-mediated autophagy,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001774~microglial cell activation,GO:0001921~positive regulation of receptor recycling,GO:0001933~negative regulation of protein phosphorylation,GO:0001956~positive regulation of neurotransmitter secretion,GO:0006631~fatty acid metabolic process,GO:0006638~neutral lipid metabolic process,GO:0006644~phospholipid metabolic process,GO:0006915~apoptotic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0007006~mitochondrial membrane organization,GO:0007568~aging,GO:0008344~adult locomotory behavior,GO:0010040~response to iron(II) ion,GO:0010517~regulation of phospholipase activity,GO:0010642~negative regulation of platelet-derived growth factor receptor signaling pathway,GO:0014048~regulation of glutamate secretion,GO:0014059~regulation of dopamine secretion,GO:0031115~negative regulation of microtubule polymerization,GO:0031623~receptor internalization,GO:0031648~protein destabilization,GO:0032026~response to magnesium ion,GO:0032410~negative regulation of transporter activity,GO:0032496~response to lipopolysaccharide,GO:0032769~negative regulation of monooxygenase activity,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0034341~response to interferon-gamma,GO:0034599~cellular response to oxidative stress,GO:0035067~negative regulation of histone acetylation,GO:0040012~regulation of locomotion,GO:0042416~dopamine biosynthetic process,GO:0042493~response to drug,GO:0042775~mitochondrial ATP synthesis coupled electron transport,GO:0043030~regulation of macrophage activation,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0043206~extracellular fibril organization,GO:0043524~negative regulation of neuron apoptotic process,GO:0044267~cellular protein metabolic process,GO:0044344~cellular response to fibroblast growth factor stimulus,GO:0045807~positive regulation of endocytosis,GO:0045920~negative regulation of exocytosis,GO:0045963~negative regulation of dopamine metabolic process,GO:0048148~behavioral response to cocaine,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048488~synaptic vesicle endocytosis,GO:0050808~synapse organization,GO:0050812~regulation of acyl-CoA biosynthetic process,GO:0051281~positive regulation of release of sequestered calcium ion into cytosol,GO:0051583~dopamine uptake involved in synaptic transmission,GO:0051585~negative regulation of dopamine uptake involved in synaptic transmission,GO:0051612~negative regulation of serotonin uptake,GO:0051622~negative regulation of norepinephrine uptake,GO:0055074~calcium ion homeostasis,GO:0055114~oxidation-reduction process,GO:0060079~excitatory postsynaptic potential,GO:0060291~long-term synaptic potentiation,GO:0060732~positive regulation of inositol phosphate biosynthetic process,GO:0070495~negative regulation of thrombin receptor signaling pathway,GO:0070555~response to interleukin-1,GO:0071280~cellular response to copper ion,GO:0071872~cellular response to epinephrine stimulus,GO:0071902~positive regulation of protein serine/threonine kinase activity,GO:1901215~negative regulation of neuron death,GO:1902957~negative regulation of mitochondrial electron transport, NADH to ubiquinone,GO:1903284~positive regulation of glutathione peroxidase activity,GO:1903285~positive regulation of hydrogen peroxide catabolic process,GO:1903421~regulation of synaptic vesicle recycling,GO:1903426~regulation of reactive oxygen species biosynthetic process,GO:1904715~negative regulation of chaperone-mediated autophagy,"]
[6,"CDK5","cyclin dependent kinase 5(CDK5)","Homo sapiens",70,69,69.5,139,"GO:0001764~neuron migration,GO:0001963~synaptic transmission, dopaminergic,GO:0006886~intracellular protein transport,GO:0006913~nucleocytoplasmic transport,GO:0007049~cell cycle,GO:0007160~cell-matrix adhesion,GO:0007268~chemical synaptic transmission,GO:0007416~synapse assembly,GO:0007519~skeletal muscle tissue development,GO:0008045~motor neuron axon guidance,GO:0008283~cell proliferation,GO:0008542~visual learning,GO:0009611~response to wounding,GO:0014044~Schwann cell development,GO:0016079~synaptic vesicle exocytosis,GO:0016241~regulation of macroautophagy,GO:0016310~phosphorylation,GO:0018105~peptidyl-serine phosphorylation,GO:0018107~peptidyl-threonine phosphorylation,GO:0019233~sensory perception of pain,GO:0021697~cerebellar cortex formation,GO:0021766~hippocampus development,GO:0021819~layer formation in cerebral cortex,GO:0021954~central nervous system neuron development,GO:0022038~corpus callosum development,GO:0030182~neuron differentiation,GO:0030334~regulation of cell migration,GO:0030517~negative regulation of axon extension,GO:0030866~cortical actin cytoskeleton organization,GO:0031175~neuron projection development,GO:0031397~negative regulation of protein ubiquitination,GO:0031914~negative regulation of synaptic plasticity,GO:0032092~positive regulation of protein binding,GO:0032801~receptor catabolic process,GO:0033136~serine phosphorylation of STAT3 protein,GO:0035249~synaptic transmission, glutamatergic,GO:0035418~protein localization to synapse,GO:0042981~regulation of apoptotic process,GO:0043113~receptor clustering,GO:0043525~positive regulation of neuron apoptotic process,GO:0045055~regulated exocytosis,GO:0045786~negative regulation of cell cycle,GO:0045860~positive regulation of protein kinase activity,GO:0045861~negative regulation of proteolysis,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045956~positive regulation of calcium ion-dependent exocytosis,GO:0046777~protein autophosphorylation,GO:0046826~negative regulation of protein export from nucleus,GO:0048148~behavioral response to cocaine,GO:0048167~regulation of synaptic plasticity,GO:0048488~synaptic vesicle endocytosis,GO:0048511~rhythmic process,GO:0048675~axon extension,GO:0048709~oligodendrocyte differentiation,GO:0048813~dendrite morphogenesis,GO:0051301~cell division,GO:0051402~neuron apoptotic process,GO:0060079~excitatory postsynaptic potential,GO:0061001~regulation of dendritic spine morphogenesis,GO:0070509~calcium ion import,GO:0071156~regulation of cell cycle arrest,GO:0090314~positive regulation of protein targeting to membrane,GO:1901215~negative regulation of neuron death,GO:1901796~regulation of signal transduction by p53 class mediator,GO:1903421~regulation of synaptic vesicle recycling,GO:2000251~positive regulation of actin cytoskeleton reorganization,GO:2000273~positive regulation of receptor activity,","GO:0001764~neuron migration,GO:0001963~synaptic transmission, dopaminergic,GO:0006886~intracellular protein transport,GO:0006913~nucleocytoplasmic transport,GO:0007049~cell cycle,GO:0007160~cell-matrix adhesion,GO:0007268~chemical synaptic transmission,GO:0007416~synapse assembly,GO:0007519~skeletal muscle tissue development,GO:0008045~motor neuron axon guidance,GO:0008283~cell proliferation,GO:0008542~visual learning,GO:0009611~response to wounding,GO:0014044~Schwann cell development,GO:0016079~synaptic vesicle exocytosis,GO:0016241~regulation of macroautophagy,GO:0016310~phosphorylation,GO:0018105~peptidyl-serine phosphorylation,GO:0018107~peptidyl-threonine phosphorylation,GO:0019233~sensory perception of pain,GO:0021697~cerebellar cortex formation,GO:0021766~hippocampus development,GO:0021819~layer formation in cerebral cortex,GO:0021954~central nervous system neuron development,GO:0022038~corpus callosum development,GO:0030182~neuron differentiation,GO:0030334~regulation of cell migration,GO:0030517~negative regulation of axon extension,GO:0030866~cortical actin cytoskeleton organization,GO:0031175~neuron projection development,GO:0031397~negative regulation of protein ubiquitination,GO:0031914~negative regulation of synaptic plasticity,GO:0032092~positive regulation of protein binding,GO:0032801~receptor catabolic process,GO:0033136~serine phosphorylation of STAT3 protein,GO:0035249~synaptic transmission, glutamatergic,GO:0035418~protein localization to synapse,GO:0042981~regulation of apoptotic process,GO:0043113~receptor clustering,GO:0043525~positive regulation of neuron apoptotic process,GO:0045055~regulated exocytosis,GO:0045786~negative regulation of cell cycle,GO:0045860~positive regulation of protein kinase activity,GO:0045861~negative regulation of proteolysis,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045956~positive regulation of calcium ion-dependent exocytosis,GO:0046777~protein autophosphorylation,GO:0046826~negative regulation of protein export from nucleus,GO:0048148~behavioral response to cocaine,GO:0048167~regulation of synaptic plasticity,GO:0048488~synaptic vesicle endocytosis,GO:0048511~rhythmic process,GO:0048675~axon extension,GO:0048709~oligodendrocyte differentiation,GO:0048813~dendrite morphogenesis,GO:0051301~cell division,GO:0051402~neuron apoptotic process,GO:0060079~excitatory postsynaptic potential,GO:0061001~regulation of dendritic spine morphogenesis,GO:0070509~calcium ion import,GO:0071156~regulation of cell cycle arrest,GO:0090314~positive regulation of protein targeting to membrane,GO:1901215~negative regulation of neuron death,GO:1901796~regulation of signal transduction by p53 class mediator,GO:1903421~regulation of synaptic vesicle recycling,GO:2000251~positive regulation of actin cytoskeleton reorganization,GO:2000273~positive regulation of receptor activity,"]
[7,"IL10","interleukin 10(IL10)","Homo sapiens",69,69,69,138,"GO:0002237~response to molecule of bacterial origin,GO:0002740~negative regulation of cytokine secretion involved in immune response,GO:0002875~negative regulation of chronic inflammatory response to antigenic stimulus,GO:0002904~positive regulation of B cell apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0007253~cytoplasmic sequestering of NF-kappaB,GO:0007267~cell-cell signaling,GO:0007568~aging,GO:0008285~negative regulation of cell proliferation,GO:0010468~regulation of gene expression,GO:0014823~response to activity,GO:0014854~response to inactivity,GO:0030097~hemopoiesis,GO:0030183~B cell differentiation,GO:0030595~leukocyte chemotaxis,GO:0030886~negative regulation of myeloid dendritic cell activation,GO:0030889~negative regulation of B cell proliferation,GO:0032689~negative regulation of interferon-gamma production,GO:0032692~negative regulation of interleukin-1 production,GO:0032695~negative regulation of interleukin-12 production,GO:0032701~negative regulation of interleukin-18 production,GO:0032715~negative regulation of interleukin-6 production,GO:0032717~negative regulation of interleukin-8 production,GO:0032720~negative regulation of tumor necrosis factor production,GO:0032800~receptor biosynthetic process,GO:0032868~response to insulin,GO:0034115~negative regulation of heterotypic cell-cell adhesion,GO:0034116~positive regulation of heterotypic cell-cell adhesion,GO:0034465~response to carbon monoxide,GO:0035729~cellular response to hepatocyte growth factor stimulus,GO:0042092~type 2 immune response,GO:0042100~B cell proliferation,GO:0042130~negative regulation of T cell proliferation,GO:0042493~response to drug,GO:0042536~negative regulation of tumor necrosis factor biosynthetic process,GO:0042742~defense response to bacterium,GO:0042832~defense response to protozoan,GO:0043032~positive regulation of macrophage activation,GO:0043066~negative regulation of apoptotic process,GO:0044130~negative regulation of growth of symbiont in host,GO:0045019~negative regulation of nitric oxide biosynthetic process,GO:0045191~regulation of isotype switching,GO:0045347~negative regulation of MHC class II biosynthetic process,GO:0045348~positive regulation of MHC class II biosynthetic process,GO:0045355~negative regulation of interferon-alpha biosynthetic process,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045930~negative regulation of mitotic cell cycle,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046427~positive regulation of JAK-STAT cascade,GO:0050715~positive regulation of cytokine secretion,GO:0050807~regulation of synapse organization,GO:0051045~negative regulation of membrane protein ectodomain proteolysis,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051384~response to glucocorticoid,GO:0060302~negative regulation of cytokine activity,GO:0060670~branching involved in labyrinthine layer morphogenesis,GO:0071222~cellular response to lipopolysaccharide,GO:0071392~cellular response to estradiol stimulus,GO:0071650~negative regulation of chemokine (C-C motif) ligand 5 production,GO:0072577~endothelial cell apoptotic process,GO:0097421~liver regeneration,GO:1903034~regulation of response to wounding,GO:1903659~regulation of complement-dependent cytotoxicity,GO:1904057~negative regulation of sensory perception of pain,GO:1904706~negative regulation of vascular smooth muscle cell proliferation,GO:1904707~positive regulation of vascular smooth muscle cell proliferation,GO:2000352~negative regulation of endothelial cell apoptotic process,","GO:0002237~response to molecule of bacterial origin,GO:0002740~negative regulation of cytokine secretion involved in immune response,GO:0002875~negative regulation of chronic inflammatory response to antigenic stimulus,GO:0002904~positive regulation of B cell apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0007253~cytoplasmic sequestering of NF-kappaB,GO:0007267~cell-cell signaling,GO:0007568~aging,GO:0008285~negative regulation of cell proliferation,GO:0010468~regulation of gene expression,GO:0014823~response to activity,GO:0014854~response to inactivity,GO:0030097~hemopoiesis,GO:0030183~B cell differentiation,GO:0030595~leukocyte chemotaxis,GO:0030886~negative regulation of myeloid dendritic cell activation,GO:0030889~negative regulation of B cell proliferation,GO:0032689~negative regulation of interferon-gamma production,GO:0032692~negative regulation of interleukin-1 production,GO:0032695~negative regulation of interleukin-12 production,GO:0032701~negative regulation of interleukin-18 production,GO:0032715~negative regulation of interleukin-6 production,GO:0032717~negative regulation of interleukin-8 production,GO:0032720~negative regulation of tumor necrosis factor production,GO:0032800~receptor biosynthetic process,GO:0032868~response to insulin,GO:0034115~negative regulation of heterotypic cell-cell adhesion,GO:0034116~positive regulation of heterotypic cell-cell adhesion,GO:0034465~response to carbon monoxide,GO:0035729~cellular response to hepatocyte growth factor stimulus,GO:0042092~type 2 immune response,GO:0042100~B cell proliferation,GO:0042130~negative regulation of T cell proliferation,GO:0042493~response to drug,GO:0042536~negative regulation of tumor necrosis factor biosynthetic process,GO:0042742~defense response to bacterium,GO:0042832~defense response to protozoan,GO:0043032~positive regulation of macrophage activation,GO:0043066~negative regulation of apoptotic process,GO:0044130~negative regulation of growth of symbiont in host,GO:0045019~negative regulation of nitric oxide biosynthetic process,GO:0045191~regulation of isotype switching,GO:0045347~negative regulation of MHC class II biosynthetic process,GO:0045348~positive regulation of MHC class II biosynthetic process,GO:0045355~negative regulation of interferon-alpha biosynthetic process,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045930~negative regulation of mitotic cell cycle,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046427~positive regulation of JAK-STAT cascade,GO:0050715~positive regulation of cytokine secretion,GO:0050807~regulation of synapse organization,GO:0051045~negative regulation of membrane protein ectodomain proteolysis,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0051384~response to glucocorticoid,GO:0060302~negative regulation of cytokine activity,GO:0060670~branching involved in labyrinthine layer morphogenesis,GO:0071222~cellular response to lipopolysaccharide,GO:0071392~cellular response to estradiol stimulus,GO:0071650~negative regulation of chemokine (C-C motif) ligand 5 production,GO:0072577~endothelial cell apoptotic process,GO:0097421~liver regeneration,GO:1903034~regulation of response to wounding,GO:1903659~regulation of complement-dependent cytotoxicity,GO:1904057~negative regulation of sensory perception of pain,GO:1904706~negative regulation of vascular smooth muscle cell proliferation,GO:1904707~positive regulation of vascular smooth muscle cell proliferation,GO:2000352~negative regulation of endothelial cell apoptotic process,"]
[8,"APP","amyloid beta precursor protein(APP)","Homo sapiens",53,53,53,106,"GO:0001878~response to yeast,GO:0001967~suckling behavior,GO:0002576~platelet degranulation,GO:0006378~mRNA polyadenylation,GO:0006417~regulation of translation,GO:0006468~protein phosphorylation,GO:0006878~cellular copper ion homeostasis,GO:0006897~endocytosis,GO:0006979~response to oxidative stress,GO:0007155~cell adhesion,GO:0007176~regulation of epidermal growth factor-activated receptor activity,GO:0007219~Notch signaling pathway,GO:0007399~nervous system development,GO:0007409~axonogenesis,GO:0007617~mating behavior,GO:0007626~locomotory behavior,GO:0008088~axo-dendritic transport,GO:0008203~cholesterol metabolic process,GO:0008344~adult locomotory behavior,GO:0008542~visual learning,GO:0009987~cellular process,GO:0010288~response to lead ion,GO:0010951~negative regulation of endopeptidase activity,GO:0010952~positive regulation of peptidase activity,GO:0010971~positive regulation of G2/M transition of mitotic cell cycle,GO:0016199~axon midline choice point recognition,GO:0016322~neuron remodeling,GO:0016358~dendrite development,GO:0019731~antibacterial humoral response,GO:0019732~antifungal humoral response,GO:0030198~extracellular matrix organization,GO:0030900~forebrain development,GO:0031175~neuron projection development,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0040014~regulation of multicellular organism growth,GO:0043393~regulation of protein binding,GO:0044267~cellular protein metabolic process,GO:0045087~innate immune response,GO:0045665~negative regulation of neuron differentiation,GO:0045931~positive regulation of mitotic cell cycle,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048669~collateral sprouting in absence of injury,GO:0050803~regulation of synapse structure or activity,GO:0050829~defense response to Gram-negative bacterium,GO:0050830~defense response to Gram-positive bacterium,GO:0050885~neuromuscular process controlling balance,GO:0051124~synaptic growth at neuromuscular junction,GO:0051402~neuron apoptotic process,GO:0051563~smooth endoplasmic reticulum calcium ion homeostasis,GO:0071320~cellular response to cAMP,GO:0071874~cellular response to norepinephrine stimulus,GO:1990000~amyloid fibril formation,GO:1990090~cellular response to nerve growth factor stimulus,","GO:0001878~response to yeast,GO:0001967~suckling behavior,GO:0002576~platelet degranulation,GO:0006378~mRNA polyadenylation,GO:0006417~regulation of translation,GO:0006468~protein phosphorylation,GO:0006878~cellular copper ion homeostasis,GO:0006897~endocytosis,GO:0006979~response to oxidative stress,GO:0007155~cell adhesion,GO:0007176~regulation of epidermal growth factor-activated receptor activity,GO:0007219~Notch signaling pathway,GO:0007399~nervous system development,GO:0007409~axonogenesis,GO:0007617~mating behavior,GO:0007626~locomotory behavior,GO:0008088~axo-dendritic transport,GO:0008203~cholesterol metabolic process,GO:0008344~adult locomotory behavior,GO:0008542~visual learning,GO:0009987~cellular process,GO:0010288~response to lead ion,GO:0010951~negative regulation of endopeptidase activity,GO:0010952~positive regulation of peptidase activity,GO:0010971~positive regulation of G2/M transition of mitotic cell cycle,GO:0016199~axon midline choice point recognition,GO:0016322~neuron remodeling,GO:0016358~dendrite development,GO:0019731~antibacterial humoral response,GO:0019732~antifungal humoral response,GO:0030198~extracellular matrix organization,GO:0030900~forebrain development,GO:0031175~neuron projection development,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0040014~regulation of multicellular organism growth,GO:0043393~regulation of protein binding,GO:0044267~cellular protein metabolic process,GO:0045087~innate immune response,GO:0045665~negative regulation of neuron differentiation,GO:0045931~positive regulation of mitotic cell cycle,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048669~collateral sprouting in absence of injury,GO:0050803~regulation of synapse structure or activity,GO:0050829~defense response to Gram-negative bacterium,GO:0050830~defense response to Gram-positive bacterium,GO:0050885~neuromuscular process controlling balance,GO:0051124~synaptic growth at neuromuscular junction,GO:0051402~neuron apoptotic process,GO:0051563~smooth endoplasmic reticulum calcium ion homeostasis,GO:0071320~cellular response to cAMP,GO:0071874~cellular response to norepinephrine stimulus,GO:1990000~amyloid fibril formation,GO:1990090~cellular response to nerve growth factor stimulus,"]
[9,"TLR2","toll like receptor 2(TLR2)","Homo sapiens",51,51,51,102,"GO:0001666~response to hypoxia,GO:0001774~microglial cell activation,GO:0002237~response to molecule of bacterial origin,GO:0002374~cytokine secretion involved in immune response,GO:0002755~MyD88-dependent toll-like receptor signaling pathway,GO:0006691~leukotriene metabolic process,GO:0006915~apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0007165~signal transduction,GO:0007252~I-kappaB phosphorylation,GO:0008285~negative regulation of cell proliferation,GO:0009636~response to toxic substance,GO:0010628~positive regulation of gene expression,GO:0030177~positive regulation of Wnt signaling pathway,GO:0031663~lipopolysaccharide-mediated signaling pathway,GO:0032289~central nervous system myelin formation,GO:0032493~response to bacterial lipoprotein,GO:0032496~response to lipopolysaccharide,GO:0032570~response to progesterone,GO:0032613~interleukin-10 production,GO:0032722~positive regulation of chemokine production,GO:0032728~positive regulation of interferon-beta production,GO:0032733~positive regulation of interleukin-10 production,GO:0032735~positive regulation of interleukin-12 production,GO:0032741~positive regulation of interleukin-18 production,GO:0032755~positive regulation of interleukin-6 production,GO:0032757~positive regulation of interleukin-8 production,GO:0032760~positive regulation of tumor necrosis factor production,GO:0032868~response to insulin,GO:0034123~positive regulation of toll-like receptor signaling pathway,GO:0034134~toll-like receptor 2 signaling pathway,GO:0038123~toll-like receptor TLR1:TLR2 signaling pathway,GO:0038124~toll-like receptor TLR6:TLR2 signaling pathway,GO:0042346~positive regulation of NF-kappaB import into nucleus,GO:0042495~detection of triacyl bacterial lipopeptide,GO:0042496~detection of diacyl bacterial lipopeptide,GO:0045087~innate immune response,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046209~nitric oxide metabolic process,GO:0048714~positive regulation of oligodendrocyte differentiation,GO:0050707~regulation of cytokine secretion,GO:0050729~positive regulation of inflammatory response,GO:0050830~defense response to Gram-positive bacterium,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051770~positive regulation of nitric-oxide synthase biosynthetic process,GO:0070542~response to fatty acid,GO:0071221~cellular response to bacterial lipopeptide,GO:0071223~cellular response to lipoteichoic acid,GO:0071726~cellular response to diacyl bacterial lipopeptide,GO:0071727~cellular response to triacyl bacterial lipopeptide,","GO:0001666~response to hypoxia,GO:0001774~microglial cell activation,GO:0002237~response to molecule of bacterial origin,GO:0002374~cytokine secretion involved in immune response,GO:0002755~MyD88-dependent toll-like receptor signaling pathway,GO:0006691~leukotriene metabolic process,GO:0006915~apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0007165~signal transduction,GO:0007252~I-kappaB phosphorylation,GO:0008285~negative regulation of cell proliferation,GO:0009636~response to toxic substance,GO:0010628~positive regulation of gene expression,GO:0030177~positive regulation of Wnt signaling pathway,GO:0031663~lipopolysaccharide-mediated signaling pathway,GO:0032289~central nervous system myelin formation,GO:0032493~response to bacterial lipoprotein,GO:0032496~response to lipopolysaccharide,GO:0032570~response to progesterone,GO:0032613~interleukin-10 production,GO:0032722~positive regulation of chemokine production,GO:0032728~positive regulation of interferon-beta production,GO:0032733~positive regulation of interleukin-10 production,GO:0032735~positive regulation of interleukin-12 production,GO:0032741~positive regulation of interleukin-18 production,GO:0032755~positive regulation of interleukin-6 production,GO:0032757~positive regulation of interleukin-8 production,GO:0032760~positive regulation of tumor necrosis factor production,GO:0032868~response to insulin,GO:0034123~positive regulation of toll-like receptor signaling pathway,GO:0034134~toll-like receptor 2 signaling pathway,GO:0038123~toll-like receptor TLR1:TLR2 signaling pathway,GO:0038124~toll-like receptor TLR6:TLR2 signaling pathway,GO:0042346~positive regulation of NF-kappaB import into nucleus,GO:0042495~detection of triacyl bacterial lipopeptide,GO:0042496~detection of diacyl bacterial lipopeptide,GO:0045087~innate immune response,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046209~nitric oxide metabolic process,GO:0048714~positive regulation of oligodendrocyte differentiation,GO:0050707~regulation of cytokine secretion,GO:0050729~positive regulation of inflammatory response,GO:0050830~defense response to Gram-positive bacterium,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051770~positive regulation of nitric-oxide synthase biosynthetic process,GO:0070542~response to fatty acid,GO:0071221~cellular response to bacterial lipopeptide,GO:0071223~cellular response to lipoteichoic acid,GO:0071726~cellular response to diacyl bacterial lipopeptide,GO:0071727~cellular response to triacyl bacterial lipopeptide,"]
[10,"DRD1","dopamine receptor D1(DRD1)","Homo sapiens",51,49,50,100,"GO:0001659~temperature homeostasis,GO:0001661~conditioned taste aversion,GO:0001662~behavioral fear response,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0006606~protein import into nucleus,GO:0007187~G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger,GO:0007189~adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0007190~activation of adenylate cyclase activity,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007416~synapse assembly,GO:0007612~learning,GO:0007613~memory,GO:0007617~mating behavior,GO:0007625~grooming behavior,GO:0007628~adult walking behavior,GO:0008542~visual learning,GO:0010579~positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway,GO:0014002~astrocyte development,GO:0015872~dopamine transport,GO:0019226~transmission of nerve impulse,GO:0019228~neuronal action potential,GO:0021542~dentate gyrus development,GO:0021756~striatum development,GO:0021853~cerebral cortex GABAergic interneuron migration,GO:0030335~positive regulation of cell migration,GO:0030432~peristalsis,GO:0030819~positive regulation of cAMP biosynthetic process,GO:0035106~operant conditioning,GO:0042053~regulation of dopamine metabolic process,GO:0042311~vasodilation,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0042711~maternal behavior,GO:0043268~positive regulation of potassium ion transport,GO:0046323~glucose import,GO:0046959~habituation,GO:0046960~sensitization,GO:0048148~behavioral response to cocaine,GO:0051281~positive regulation of release of sequestered calcium ion into cytosol,GO:0051482~positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051968~positive regulation of synaptic transmission, glutamatergic,GO:0060134~prepulse inhibition,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060291~long-term synaptic potentiation,GO:0060292~long term synaptic depression,GO:0071870~cellular response to catecholamine stimulus,","GO:0001659~temperature homeostasis,GO:0001661~conditioned taste aversion,GO:0001662~behavioral fear response,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0006606~protein import into nucleus,GO:0007187~G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger,GO:0007189~adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0007190~activation of adenylate cyclase activity,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007416~synapse assembly,GO:0007612~learning,GO:0007613~memory,GO:0007617~mating behavior,GO:0007625~grooming behavior,GO:0007628~adult walking behavior,GO:0008542~visual learning,GO:0010579~positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway,GO:0014002~astrocyte development,GO:0015872~dopamine transport,GO:0019226~transmission of nerve impulse,GO:0019228~neuronal action potential,GO:0021542~dentate gyrus development,GO:0021756~striatum development,GO:0021853~cerebral cortex GABAergic interneuron migration,GO:0030335~positive regulation of cell migration,GO:0030432~peristalsis,GO:0030819~positive regulation of cAMP biosynthetic process,GO:0035106~operant conditioning,GO:0042053~regulation of dopamine metabolic process,GO:0042311~vasodilation,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0042711~maternal behavior,GO:0043268~positive regulation of potassium ion transport,GO:0046323~glucose import,GO:0046959~habituation,GO:0046960~sensitization,GO:0048148~behavioral response to cocaine,GO:0051281~positive regulation of release of sequestered calcium ion into cytosol,GO:0051482~positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051968~positive regulation of synaptic transmission, glutamatergic,GO:0060134~prepulse inhibition,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060291~long-term synaptic potentiation,GO:0060292~long term synaptic depression,GO:0071870~cellular response to catecholamine stimulus,"]
[11,"CHRNB2","cholinergic receptor nicotinic beta 2 subunit(CHRNB2)","Homo sapiens",50,49,49.5,99,"GO:0001508~action potential,GO:0001661~conditioned taste aversion,GO:0001666~response to hypoxia,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006939~smooth muscle contraction,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0007601~visual perception,GO:0007605~sensory perception of sound,GO:0007612~learning,GO:0007613~memory,GO:0007626~locomotory behavior,GO:0008306~associative learning,GO:0008542~visual learning,GO:0014059~regulation of dopamine secretion,GO:0019233~sensory perception of pain,GO:0021562~vestibulocochlear nerve development,GO:0021631~optic nerve morphogenesis,GO:0021771~lateral geniculate nucleus development,GO:0021952~central nervous system projection neuron axonogenesis,GO:0030890~positive regulation of B cell proliferation,GO:0032225~regulation of synaptic transmission, dopaminergic,GO:0032226~positive regulation of synaptic transmission, dopaminergic,GO:0033603~positive regulation of dopamine secretion,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0035176~social behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042113~B cell activation,GO:0042220~response to cocaine,GO:0042320~regulation of circadian sleep/wake cycle, REM sleep,GO:0045188~regulation of circadian sleep/wake cycle, non-REM sleep,GO:0045471~response to ethanol,GO:0045759~negative regulation of action potential,GO:0048814~regulation of dendrite morphogenesis,GO:0050877~neurological system process,GO:0050890~cognition,GO:0051291~protein heterooligomerization,GO:0051899~membrane depolarization,GO:0051963~regulation of synapse assembly,GO:0060084~synaptic transmission involved in micturition,GO:0095500~acetylcholine receptor signaling pathway,GO:0098655~cation transmembrane transport,","GO:0001508~action potential,GO:0001661~conditioned taste aversion,GO:0001666~response to hypoxia,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006939~smooth muscle contraction,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0007601~visual perception,GO:0007605~sensory perception of sound,GO:0007612~learning,GO:0007613~memory,GO:0007626~locomotory behavior,GO:0008306~associative learning,GO:0008542~visual learning,GO:0014059~regulation of dopamine secretion,GO:0019233~sensory perception of pain,GO:0021562~vestibulocochlear nerve development,GO:0021631~optic nerve morphogenesis,GO:0021771~lateral geniculate nucleus development,GO:0021952~central nervous system projection neuron axonogenesis,GO:0030890~positive regulation of B cell proliferation,GO:0032225~regulation of synaptic transmission, dopaminergic,GO:0032226~positive regulation of synaptic transmission, dopaminergic,GO:0033603~positive regulation of dopamine secretion,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0035176~social behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042113~B cell activation,GO:0042220~response to cocaine,GO:0042320~regulation of circadian sleep/wake cycle, REM sleep,GO:0045188~regulation of circadian sleep/wake cycle, non-REM sleep,GO:0045471~response to ethanol,GO:0045759~negative regulation of action potential,GO:0048814~regulation of dendrite morphogenesis,GO:0050877~neurological system process,GO:0050890~cognition,GO:0051291~protein heterooligomerization,GO:0051899~membrane depolarization,GO:0051963~regulation of synapse assembly,GO:0060084~synaptic transmission involved in micturition,GO:0095500~acetylcholine receptor signaling pathway,GO:0098655~cation transmembrane transport,"]
[11,"DRD3","dopamine receptor D3(DRD3)","Homo sapiens",50,49,49.5,99,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0002016~regulation of blood volume by renin-angiotensin,GO:0002031~G-protein coupled receptor internalization,GO:0006874~cellular calcium ion homeostasis,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007611~learning or memory,GO:0007612~learning,GO:0007626~locomotory behavior,GO:0008284~positive regulation of cell proliferation,GO:0008542~visual learning,GO:0014059~regulation of dopamine secretion,GO:0019216~regulation of lipid metabolic process,GO:0030814~regulation of cAMP metabolic process,GO:0032416~negative regulation of sodium:proton antiporter activity,GO:0032467~positive regulation of cytokinesis,GO:0032922~circadian regulation of gene expression,GO:0034776~response to histamine,GO:0035176~social behavior,GO:0035483~gastric emptying,GO:0035815~positive regulation of renal sodium excretion,GO:0040014~regulation of multicellular organism growth,GO:0042220~response to cocaine,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0043278~response to morphine,GO:0045187~regulation of circadian sleep/wake cycle, sleep,GO:0045471~response to ethanol,GO:0045776~negative regulation of blood pressure,GO:0045840~positive regulation of mitotic nuclear division,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046717~acid secretion,GO:0048148~behavioral response to cocaine,GO:0048715~negative regulation of oligodendrocyte differentiation,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0050883~musculoskeletal movement, spinal reflex action,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051898~negative regulation of protein kinase B signaling,GO:0060134~prepulse inhibition,GO:0060160~negative regulation of dopamine receptor signaling pathway,GO:0060161~positive regulation of dopamine receptor signaling pathway,GO:0090325~regulation of locomotion involved in locomotory behavior,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0002016~regulation of blood volume by renin-angiotensin,GO:0002031~G-protein coupled receptor internalization,GO:0006874~cellular calcium ion homeostasis,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007611~learning or memory,GO:0007612~learning,GO:0007626~locomotory behavior,GO:0008284~positive regulation of cell proliferation,GO:0008542~visual learning,GO:0014059~regulation of dopamine secretion,GO:0019216~regulation of lipid metabolic process,GO:0030814~regulation of cAMP metabolic process,GO:0032416~negative regulation of sodium:proton antiporter activity,GO:0032467~positive regulation of cytokinesis,GO:0032922~circadian regulation of gene expression,GO:0034776~response to histamine,GO:0035176~social behavior,GO:0035483~gastric emptying,GO:0035815~positive regulation of renal sodium excretion,GO:0040014~regulation of multicellular organism growth,GO:0042220~response to cocaine,GO:0042417~dopamine metabolic process,GO:0042493~response to drug,GO:0043278~response to morphine,GO:0045187~regulation of circadian sleep/wake cycle, sleep,GO:0045471~response to ethanol,GO:0045776~negative regulation of blood pressure,GO:0045840~positive regulation of mitotic nuclear division,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046717~acid secretion,GO:0048148~behavioral response to cocaine,GO:0048715~negative regulation of oligodendrocyte differentiation,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0050883~musculoskeletal movement, spinal reflex action,GO:0051584~regulation of dopamine uptake involved in synaptic transmission,GO:0051898~negative regulation of protein kinase B signaling,GO:0060134~prepulse inhibition,GO:0060160~negative regulation of dopamine receptor signaling pathway,GO:0060161~positive regulation of dopamine receptor signaling pathway,GO:0090325~regulation of locomotion involved in locomotory behavior,"]
[12,"ESR1","estrogen receptor 1(ESR1)","Homo sapiens",46,45,45.5,91,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001547~antral ovarian follicle growth,GO:0002064~epithelial cell development,GO:0006338~chromatin remodeling,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0008209~androgen metabolic process,GO:0008584~male gonad development,GO:0010629~negative regulation of gene expression,GO:0010863~positive regulation of phospholipase C activity,GO:0030518~intracellular steroid hormone receptor signaling pathway,GO:0030520~intracellular estrogen receptor signaling pathway,GO:0032355~response to estradiol,GO:0034121~regulation of toll-like receptor signaling pathway,GO:0042981~regulation of apoptotic process,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043401~steroid hormone mediated signaling pathway,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,GO:0043627~response to estrogen,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048146~positive regulation of fibroblast proliferation,GO:0050727~regulation of inflammatory response,GO:0051000~positive regulation of nitric-oxide synthase activity,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0060065~uterus development,GO:0060068~vagina development,GO:0060523~prostate epithelial cord elongation,GO:0060527~prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis,GO:0060687~regulation of branching involved in prostate gland morphogenesis,GO:0060745~mammary gland branching involved in pregnancy,GO:0060749~mammary gland alveolus development,GO:0060750~epithelial cell proliferation involved in mammary gland duct elongation,GO:0071168~protein localization to chromatin,GO:0071391~cellular response to estrogen stimulus,GO:0071392~cellular response to estradiol stimulus,GO:1903799~negative regulation of production of miRNAs involved in gene silencing by miRNA,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001547~antral ovarian follicle growth,GO:0002064~epithelial cell development,GO:0006338~chromatin remodeling,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0008209~androgen metabolic process,GO:0008584~male gonad development,GO:0010629~negative regulation of gene expression,GO:0010863~positive regulation of phospholipase C activity,GO:0030518~intracellular steroid hormone receptor signaling pathway,GO:0030520~intracellular estrogen receptor signaling pathway,GO:0032355~response to estradiol,GO:0034121~regulation of toll-like receptor signaling pathway,GO:0042981~regulation of apoptotic process,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043401~steroid hormone mediated signaling pathway,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,GO:0043627~response to estrogen,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048146~positive regulation of fibroblast proliferation,GO:0050727~regulation of inflammatory response,GO:0051000~positive regulation of nitric-oxide synthase activity,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:0060065~uterus development,GO:0060068~vagina development,GO:0060523~prostate epithelial cord elongation,GO:0060527~prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis,GO:0060687~regulation of branching involved in prostate gland morphogenesis,GO:0060745~mammary gland branching involved in pregnancy,GO:0060749~mammary gland alveolus development,GO:0060750~epithelial cell proliferation involved in mammary gland duct elongation,GO:0071168~protein localization to chromatin,GO:0071391~cellular response to estrogen stimulus,GO:0071392~cellular response to estradiol stimulus,GO:1903799~negative regulation of production of miRNAs involved in gene silencing by miRNA,"]
[13,"RELN","reelin(RELN)","Homo sapiens",44,44,44,88,"GO:0000904~cell morphogenesis involved in differentiation,GO:0001764~neuron migration,GO:0006508~proteolysis,GO:0007155~cell adhesion,GO:0007411~axon guidance,GO:0007417~central nervous system development,GO:0007420~brain development,GO:0007616~long-term memory,GO:0008306~associative learning,GO:0010001~glial cell differentiation,GO:0010976~positive regulation of neuron projection development,GO:0014068~positive regulation of phosphatidylinositol 3-kinase signaling,GO:0016358~dendrite development,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0021511~spinal cord patterning,GO:0021517~ventral spinal cord development,GO:0021766~hippocampus development,GO:0021800~cerebral cortex tangential migration,GO:0021819~layer formation in cerebral cortex,GO:0032008~positive regulation of TOR signaling,GO:0032793~positive regulation of CREB transcription factor activity,GO:0035418~protein localization to synapse,GO:0038026~reelin-mediated signaling pathway,GO:0045860~positive regulation of protein kinase activity,GO:0048265~response to pain,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0050795~regulation of behavior,GO:0050804~modulation of synaptic transmission,GO:0051057~positive regulation of small GTPase mediated signal transduction,GO:0051968~positive regulation of synaptic transmission, glutamatergic,GO:0060291~long-term synaptic potentiation,GO:0061003~positive regulation of dendritic spine morphogenesis,GO:0061098~positive regulation of protein tyrosine kinase activity,GO:0090129~positive regulation of synapse maturation,GO:0097114~NMDA glutamate receptor clustering,GO:0097119~postsynaptic density protein 95 clustering,GO:0097120~receptor localization to synapse,GO:0097477~lateral motor column neuron migration,GO:1900273~positive regulation of long-term synaptic potentiation,GO:1902078~positive regulation of lateral motor column neuron migration,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:2000463~positive regulation of excitatory postsynaptic potential,GO:2000969~positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,","GO:0000904~cell morphogenesis involved in differentiation,GO:0001764~neuron migration,GO:0006508~proteolysis,GO:0007155~cell adhesion,GO:0007411~axon guidance,GO:0007417~central nervous system development,GO:0007420~brain development,GO:0007616~long-term memory,GO:0008306~associative learning,GO:0010001~glial cell differentiation,GO:0010976~positive regulation of neuron projection development,GO:0014068~positive regulation of phosphatidylinositol 3-kinase signaling,GO:0016358~dendrite development,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0021511~spinal cord patterning,GO:0021517~ventral spinal cord development,GO:0021766~hippocampus development,GO:0021800~cerebral cortex tangential migration,GO:0021819~layer formation in cerebral cortex,GO:0032008~positive regulation of TOR signaling,GO:0032793~positive regulation of CREB transcription factor activity,GO:0035418~protein localization to synapse,GO:0038026~reelin-mediated signaling pathway,GO:0045860~positive regulation of protein kinase activity,GO:0048265~response to pain,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0050795~regulation of behavior,GO:0050804~modulation of synaptic transmission,GO:0051057~positive regulation of small GTPase mediated signal transduction,GO:0051968~positive regulation of synaptic transmission, glutamatergic,GO:0060291~long-term synaptic potentiation,GO:0061003~positive regulation of dendritic spine morphogenesis,GO:0061098~positive regulation of protein tyrosine kinase activity,GO:0090129~positive regulation of synapse maturation,GO:0097114~NMDA glutamate receptor clustering,GO:0097119~postsynaptic density protein 95 clustering,GO:0097120~receptor localization to synapse,GO:0097477~lateral motor column neuron migration,GO:1900273~positive regulation of long-term synaptic potentiation,GO:1902078~positive regulation of lateral motor column neuron migration,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:2000463~positive regulation of excitatory postsynaptic potential,GO:2000969~positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity,"]
[14,"IFNG","interferon gamma(IFNG)","Homo sapiens",79,0,39.5,79,"GO:0000060~protein import into nucleus, translocation,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001781~neutrophil apoptotic process,GO:0002026~regulation of the force of heart contraction,GO:0002250~adaptive immune response,GO:0002302~CD8-positive, alpha-beta T cell differentiation involved in immune response,GO:0006915~apoptotic process,GO:0006928~movement of cell or subcellular component,GO:0006955~immune response,GO:0006959~humoral immune response,GO:0007050~cell cycle arrest,GO:0007166~cell surface receptor signaling pathway,GO:0008284~positive regulation of cell proliferation,GO:0009615~response to virus,GO:0010508~positive regulation of autophagy,GO:0010628~positive regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0010634~positive regulation of epithelial cell migration,GO:0019882~antigen processing and presentation,GO:0030593~neutrophil chemotaxis,GO:0030857~negative regulation of epithelial cell differentiation,GO:0030968~endoplasmic reticulum unfolded protein response,GO:0031642~negative regulation of myelination,GO:0032224~positive regulation of synaptic transmission, cholinergic,GO:0032700~negative regulation of interleukin-17 production,GO:0032735~positive regulation of interleukin-12 production,GO:0032747~positive regulation of interleukin-23 production,GO:0032760~positive regulation of tumor necrosis factor production,GO:0032834~positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response,GO:0033141~positive regulation of peptidyl-serine phosphorylation of STAT protein,GO:0034393~positive regulation of smooth muscle cell apoptotic process,GO:0040008~regulation of growth,GO:0042102~positive regulation of T cell proliferation,GO:0042493~response to drug,GO:0042511~positive regulation of tyrosine phosphorylation of Stat1 protein,GO:0042742~defense response to bacterium,GO:0042832~defense response to protozoan,GO:0044130~negative regulation of growth of symbiont in host,GO:0045080~positive regulation of chemokine biosynthetic process,GO:0045084~positive regulation of interleukin-12 biosynthetic process,GO:0045348~positive regulation of MHC class II biosynthetic process,GO:0045410~positive regulation of interleukin-6 biosynthetic process,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045666~positive regulation of neuron differentiation,GO:0045672~positive regulation of osteoclast differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048147~negative regulation of fibroblast proliferation,GO:0048304~positive regulation of isotype switching to IgG isotypes,GO:0048662~negative regulation of smooth muscle cell proliferation,GO:0050718~positive regulation of interleukin-1 beta secretion,GO:0050796~regulation of insulin secretion,GO:0050852~T cell receptor signaling pathway,GO:0050954~sensory perception of mechanical stimulus,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051607~defense response to virus,GO:0051712~positive regulation of killing of cells of other organism,GO:0060251~regulation of glial cell proliferation,GO:0060333~interferon-gamma-mediated signaling pathway,GO:0060334~regulation of interferon-gamma-mediated signaling pathway,GO:0060550~positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity,GO:0060552~positive regulation of fructose 1,6-bisphosphate metabolic process,GO:0060557~positive regulation of vitamin D biosynthetic process,GO:0060559~positive regulation of calcidiol 1-monooxygenase activity,GO:0071222~cellular response to lipopolysaccharide,GO:0071351~cellular response to interleukin-18,GO:0072125~negative regulation of glomerular mesangial cell proliferation,GO:0090004~positive regulation of establishment of protein localization to plasma membrane,GO:0097191~extrinsic apoptotic signaling pathway,GO:0098908~regulation of neuronal action potential,GO:1903543~positive regulation of exosomal secretion,GO:2000309~positive regulation of tumor necrosis factor (ligand) superfamily member 11 production,GO:2000345~regulation of hepatocyte proliferation,"]
[15,"ADRA2A","adrenoceptor alpha 2A(ADRA2A)","Homo sapiens",39,39,39,78,"GO:0001819~positive regulation of cytokine production,GO:0006928~movement of cell or subcellular component,GO:0006940~regulation of smooth muscle contraction,GO:0007165~signal transduction,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007265~Ras protein signal transduction,GO:0007266~Rho protein signal transduction,GO:0008284~positive regulation of cell proliferation,GO:0010700~negative regulation of norepinephrine secretion,GO:0019229~regulation of vasoconstriction,GO:0030036~actin cytoskeleton organization,GO:0030168~platelet activation,GO:0030335~positive regulation of cell migration,GO:0030818~negative regulation of cAMP biosynthetic process,GO:0032147~activation of protein kinase activity,GO:0032148~activation of protein kinase B activity,GO:0032811~negative regulation of epinephrine secretion,GO:0032870~cellular response to hormone stimulus,GO:0035625~epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway,GO:0042593~glucose homeostasis,GO:0043268~positive regulation of potassium ion transport,GO:0043406~positive regulation of MAP kinase activity,GO:0045741~positive regulation of epidermal growth factor-activated receptor activity,GO:0045955~negative regulation of calcium ion-dependent exocytosis,GO:0046676~negative regulation of insulin secretion,GO:0050796~regulation of insulin secretion,GO:0050892~intestinal absorption,GO:0050995~negative regulation of lipid catabolic process,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051926~negative regulation of calcium ion transport,GO:0061179~negative regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0071878~negative regulation of adrenergic receptor signaling pathway,GO:0071880~adenylate cyclase-activating adrenergic receptor signaling pathway,GO:0071881~adenylate cyclase-inhibiting adrenergic receptor signaling pathway,GO:0071882~phospholipase C-activating adrenergic receptor signaling pathway,GO:0071883~activation of MAPK activity by adrenergic receptor signaling pathway,GO:0090303~positive regulation of wound healing,GO:1901020~negative regulation of calcium ion transmembrane transporter activity,","GO:0001819~positive regulation of cytokine production,GO:0006928~movement of cell or subcellular component,GO:0006940~regulation of smooth muscle contraction,GO:0007165~signal transduction,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007265~Ras protein signal transduction,GO:0007266~Rho protein signal transduction,GO:0008284~positive regulation of cell proliferation,GO:0010700~negative regulation of norepinephrine secretion,GO:0019229~regulation of vasoconstriction,GO:0030036~actin cytoskeleton organization,GO:0030168~platelet activation,GO:0030335~positive regulation of cell migration,GO:0030818~negative regulation of cAMP biosynthetic process,GO:0032147~activation of protein kinase activity,GO:0032148~activation of protein kinase B activity,GO:0032811~negative regulation of epinephrine secretion,GO:0032870~cellular response to hormone stimulus,GO:0035625~epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway,GO:0042593~glucose homeostasis,GO:0043268~positive regulation of potassium ion transport,GO:0043406~positive regulation of MAP kinase activity,GO:0045741~positive regulation of epidermal growth factor-activated receptor activity,GO:0045955~negative regulation of calcium ion-dependent exocytosis,GO:0046676~negative regulation of insulin secretion,GO:0050796~regulation of insulin secretion,GO:0050892~intestinal absorption,GO:0050995~negative regulation of lipid catabolic process,GO:0051044~positive regulation of membrane protein ectodomain proteolysis,GO:0051926~negative regulation of calcium ion transport,GO:0061179~negative regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0071878~negative regulation of adrenergic receptor signaling pathway,GO:0071880~adenylate cyclase-activating adrenergic receptor signaling pathway,GO:0071881~adenylate cyclase-inhibiting adrenergic receptor signaling pathway,GO:0071882~phospholipase C-activating adrenergic receptor signaling pathway,GO:0071883~activation of MAPK activity by adrenergic receptor signaling pathway,GO:0090303~positive regulation of wound healing,GO:1901020~negative regulation of calcium ion transmembrane transporter activity,"]
[15,"GRIN1","glutamate ionotropic receptor NMDA type subunit 1(GRIN1)","Homo sapiens",39,39,39,78,"GO:0000165~MAPK cascade,GO:0001661~conditioned taste aversion,GO:0001967~suckling behavior,GO:0001975~response to amphetamine,GO:0006812~cation transport,GO:0006874~cellular calcium ion homeostasis,GO:0007268~chemical synaptic transmission,GO:0007585~respiratory gaseous exchange,GO:0007616~long-term memory,GO:0008344~adult locomotory behavior,GO:0008355~olfactory learning,GO:0008542~visual learning,GO:0018964~propylene metabolic process,GO:0019233~sensory perception of pain,GO:0021586~pons maturation,GO:0021987~cerebral cortex development,GO:0035176~social behavior,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0035249~synaptic transmission, glutamatergic,GO:0042391~regulation of membrane potential,GO:0043065~positive regulation of apoptotic process,GO:0043278~response to morphine,GO:0043524~negative regulation of neuron apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0043576~regulation of respiratory gaseous exchange,GO:0045471~response to ethanol,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048013~ephrin receptor signaling pathway,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048814~regulation of dendrite morphogenesis,GO:0050770~regulation of axonogenesis,GO:0051963~regulation of synapse assembly,GO:0055074~calcium ion homeostasis,GO:0060079~excitatory postsynaptic potential,GO:0060134~prepulse inhibition,GO:0060179~male mating behavior,GO:0070588~calcium ion transmembrane transport,GO:2000463~positive regulation of excitatory postsynaptic potential,","GO:0000165~MAPK cascade,GO:0001661~conditioned taste aversion,GO:0001967~suckling behavior,GO:0001975~response to amphetamine,GO:0006812~cation transport,GO:0006874~cellular calcium ion homeostasis,GO:0007268~chemical synaptic transmission,GO:0007585~respiratory gaseous exchange,GO:0007616~long-term memory,GO:0008344~adult locomotory behavior,GO:0008355~olfactory learning,GO:0008542~visual learning,GO:0018964~propylene metabolic process,GO:0019233~sensory perception of pain,GO:0021586~pons maturation,GO:0021987~cerebral cortex development,GO:0035176~social behavior,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0035249~synaptic transmission, glutamatergic,GO:0042391~regulation of membrane potential,GO:0043065~positive regulation of apoptotic process,GO:0043278~response to morphine,GO:0043524~negative regulation of neuron apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0043576~regulation of respiratory gaseous exchange,GO:0045471~response to ethanol,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048013~ephrin receptor signaling pathway,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048814~regulation of dendrite morphogenesis,GO:0050770~regulation of axonogenesis,GO:0051963~regulation of synapse assembly,GO:0055074~calcium ion homeostasis,GO:0060079~excitatory postsynaptic potential,GO:0060134~prepulse inhibition,GO:0060179~male mating behavior,GO:0070588~calcium ion transmembrane transport,GO:2000463~positive regulation of excitatory postsynaptic potential,"]
[16,"DMD","dystrophin(DMD)","Homo sapiens",39,38,38.5,77,"GO:0001954~positive regulation of cell-matrix adhesion,GO:0002027~regulation of heart rate,GO:0006355~regulation of transcription, DNA-templated,GO:0007010~cytoskeleton organization,GO:0007517~muscle organ development,GO:0007519~skeletal muscle tissue development,GO:0007568~aging,GO:0008065~establishment of blood-nerve barrier,GO:0010880~regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,GO:0010881~regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion,GO:0010976~positive regulation of neuron projection development,GO:0014809~regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion,GO:0014819~regulation of skeletal muscle contraction,GO:0014904~myotube cell development,GO:0016203~muscle attachment,GO:0021629~olfactory nerve structural organization,GO:0030049~muscle filament sliding,GO:0033137~negative regulation of peptidyl-serine phosphorylation,GO:0034613~cellular protein localization,GO:0035994~response to muscle stretch,GO:0043043~peptide biosynthetic process,GO:0043623~cellular protein complex assembly,GO:0044458~motile cilium assembly,GO:0045213~neurotransmitter receptor metabolic process,GO:0045666~positive regulation of neuron differentiation,GO:0046716~muscle cell cellular homeostasis,GO:0048747~muscle fiber development,GO:0048812~neuron projection morphogenesis,GO:0051647~nucleus localization,GO:0060048~cardiac muscle contraction,GO:0060314~regulation of ryanodine-sensitive calcium-release channel activity,GO:0060857~establishment of glial blood-brain barrier,GO:0070373~negative regulation of ERK1 and ERK2 cascade,GO:0086001~cardiac muscle cell action potential,GO:0090287~regulation of cellular response to growth factor stimulus,GO:1901385~regulation of voltage-gated calcium channel activity,GO:1902083~negative regulation of peptidyl-cysteine S-nitrosylation,GO:2000651~positive regulation of sodium ion transmembrane transporter activity,","GO:0001954~positive regulation of cell-matrix adhesion,GO:0002027~regulation of heart rate,GO:0006355~regulation of transcription, DNA-templated,GO:0007010~cytoskeleton organization,GO:0007517~muscle organ development,GO:0007519~skeletal muscle tissue development,GO:0007568~aging,GO:0008065~establishment of blood-nerve barrier,GO:0010880~regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,GO:0010881~regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion,GO:0010976~positive regulation of neuron projection development,GO:0014809~regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion,GO:0014819~regulation of skeletal muscle contraction,GO:0014904~myotube cell development,GO:0016203~muscle attachment,GO:0021629~olfactory nerve structural organization,GO:0030049~muscle filament sliding,GO:0033137~negative regulation of peptidyl-serine phosphorylation,GO:0034613~cellular protein localization,GO:0035994~response to muscle stretch,GO:0043043~peptide biosynthetic process,GO:0043623~cellular protein complex assembly,GO:0044458~motile cilium assembly,GO:0045213~neurotransmitter receptor metabolic process,GO:0045666~positive regulation of neuron differentiation,GO:0046716~muscle cell cellular homeostasis,GO:0048747~muscle fiber development,GO:0048812~neuron projection morphogenesis,GO:0051647~nucleus localization,GO:0060048~cardiac muscle contraction,GO:0060314~regulation of ryanodine-sensitive calcium-release channel activity,GO:0060857~establishment of glial blood-brain barrier,GO:0070373~negative regulation of ERK1 and ERK2 cascade,GO:0086001~cardiac muscle cell action potential,GO:0090287~regulation of cellular response to growth factor stimulus,GO:1901385~regulation of voltage-gated calcium channel activity,GO:1902083~negative regulation of peptidyl-cysteine S-nitrosylation,GO:2000651~positive regulation of sodium ion transmembrane transporter activity,"]
[17,"OPRM1","opioid receptor mu 1(OPRM1)","Homo sapiens",38,37,37.5,75,"GO:0002438~acute inflammatory response to antigenic stimulus,GO:0007187~G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007218~neuropeptide signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007600~sensory perception,GO:0007626~locomotory behavior,GO:0008285~negative regulation of cell proliferation,GO:0009314~response to radiation,GO:0019233~sensory perception of pain,GO:0031635~adenylate cyclase-inhibiting opioid receptor signaling pathway,GO:0032094~response to food,GO:0032100~positive regulation of appetite,GO:0032496~response to lipopolysaccharide,GO:0033554~cellular response to stress,GO:0042060~wound healing,GO:0042220~response to cocaine,GO:0042755~eating behavior,GO:0043950~positive regulation of cAMP-mediated signaling,GO:0043951~negative regulation of cAMP-mediated signaling,GO:0044849~estrous cycle,GO:0045019~negative regulation of nitric oxide biosynthetic process,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0048149~behavioral response to ethanol,GO:0050769~positive regulation of neurogenesis,GO:0051481~negative regulation of cytosolic calcium ion concentration,GO:0051930~regulation of sensory perception of pain,GO:0060079~excitatory postsynaptic potential,GO:0061358~negative regulation of Wnt protein secretion,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0070588~calcium ion transmembrane transport,GO:0070848~response to growth factor,GO:0071315~cellular response to morphine,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,","GO:0002438~acute inflammatory response to antigenic stimulus,GO:0007187~G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007200~phospholipase C-activating G-protein coupled receptor signaling pathway,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007218~neuropeptide signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007600~sensory perception,GO:0007626~locomotory behavior,GO:0008285~negative regulation of cell proliferation,GO:0009314~response to radiation,GO:0019233~sensory perception of pain,GO:0031635~adenylate cyclase-inhibiting opioid receptor signaling pathway,GO:0032094~response to food,GO:0032100~positive regulation of appetite,GO:0032496~response to lipopolysaccharide,GO:0033554~cellular response to stress,GO:0042060~wound healing,GO:0042220~response to cocaine,GO:0042755~eating behavior,GO:0043950~positive regulation of cAMP-mediated signaling,GO:0043951~negative regulation of cAMP-mediated signaling,GO:0044849~estrous cycle,GO:0045019~negative regulation of nitric oxide biosynthetic process,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0048149~behavioral response to ethanol,GO:0050769~positive regulation of neurogenesis,GO:0051481~negative regulation of cytosolic calcium ion concentration,GO:0051930~regulation of sensory perception of pain,GO:0060079~excitatory postsynaptic potential,GO:0061358~negative regulation of Wnt protein secretion,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0070588~calcium ion transmembrane transport,GO:0070848~response to growth factor,GO:0071315~cellular response to morphine,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,"]
[18,"CASP3","caspase 3(CASP3)","Homo sapiens",36,36,36,72,"GO:0001666~response to hypoxia,GO:0006309~apoptotic DNA fragmentation,GO:0006508~proteolysis,GO:0006915~apoptotic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0006921~cellular component disassembly involved in execution phase of apoptosis,GO:0007611~learning or memory,GO:0008635~activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c,GO:0009749~response to glucose,GO:0010165~response to X-ray,GO:0016241~regulation of macroautophagy,GO:0021766~hippocampus development,GO:0030182~neuron differentiation,GO:0030216~keratinocyte differentiation,GO:0030218~erythrocyte differentiation,GO:0030220~platelet formation,GO:0032025~response to cobalt ion,GO:0032355~response to estradiol,GO:0032496~response to lipopolysaccharide,GO:0034349~glial cell apoptotic process,GO:0034612~response to tumor necrosis factor,GO:0035094~response to nicotine,GO:0035329~hippo signaling,GO:0042060~wound healing,GO:0042493~response to drug,GO:0042542~response to hydrogen peroxide,GO:0043066~negative regulation of apoptotic process,GO:0043200~response to amino acid,GO:0043525~positive regulation of neuron apoptotic process,GO:0046677~response to antibiotic,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0051384~response to glucocorticoid,GO:0071407~cellular response to organic cyclic compound,GO:0097190~apoptotic signaling pathway,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,GO:0097194~execution phase of apoptosis,","GO:0001666~response to hypoxia,GO:0006309~apoptotic DNA fragmentation,GO:0006508~proteolysis,GO:0006915~apoptotic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0006921~cellular component disassembly involved in execution phase of apoptosis,GO:0007611~learning or memory,GO:0008635~activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c,GO:0009749~response to glucose,GO:0010165~response to X-ray,GO:0016241~regulation of macroautophagy,GO:0021766~hippocampus development,GO:0030182~neuron differentiation,GO:0030216~keratinocyte differentiation,GO:0030218~erythrocyte differentiation,GO:0030220~platelet formation,GO:0032025~response to cobalt ion,GO:0032355~response to estradiol,GO:0032496~response to lipopolysaccharide,GO:0034349~glial cell apoptotic process,GO:0034612~response to tumor necrosis factor,GO:0035094~response to nicotine,GO:0035329~hippo signaling,GO:0042060~wound healing,GO:0042493~response to drug,GO:0042542~response to hydrogen peroxide,GO:0043066~negative regulation of apoptotic process,GO:0043200~response to amino acid,GO:0043525~positive regulation of neuron apoptotic process,GO:0046677~response to antibiotic,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0051384~response to glucocorticoid,GO:0071407~cellular response to organic cyclic compound,GO:0097190~apoptotic signaling pathway,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,GO:0097194~execution phase of apoptosis,"]
[19,"PSEN1","presenilin 1(PSEN1)","Homo sapiens",68,0,34,68,"GO:0000045~autophagosome assembly,GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000186~activation of MAPKK activity,GO:0001568~blood vessel development,GO:0001708~cell fate specification,GO:0001756~somitogenesis,GO:0001764~neuron migration,GO:0001921~positive regulation of receptor recycling,GO:0001947~heart looping,GO:0002244~hematopoietic progenitor cell differentiation,GO:0002286~T cell activation involved in immune response,GO:0003407~neural retina development,GO:0006486~protein glycosylation,GO:0006509~membrane protein ectodomain proteolysis,GO:0006839~mitochondrial transport,GO:0006974~cellular response to DNA damage stimulus,GO:0006979~response to oxidative stress,GO:0007175~negative regulation of epidermal growth factor-activated receptor activity,GO:0007219~Notch signaling pathway,GO:0007220~Notch receptor processing,GO:0007613~memory,GO:0009791~post-embryonic development,GO:0015031~protein transport,GO:0015813~L-glutamate transport,GO:0015871~choline transport,GO:0016080~synaptic vesicle targeting,GO:0016337~single organismal cell-cell adhesion,GO:0016485~protein processing,GO:0021795~cerebral cortex cell migration,GO:0021870~Cajal-Retzius cell differentiation,GO:0021904~dorsal/ventral neural tube patterning,GO:0030326~embryonic limb morphogenesis,GO:0032436~positive regulation of proteasomal ubiquitin-dependent protein catabolic process,GO:0032469~endoplasmic reticulum calcium ion homeostasis,GO:0034205~beta-amyloid formation,GO:0035556~intracellular signal transduction,GO:0042325~regulation of phosphorylation,GO:0042987~amyloid precursor protein catabolic process,GO:0043011~myeloid dendritic cell differentiation,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043085~positive regulation of catalytic activity,GO:0043393~regulation of protein binding,GO:0043406~positive regulation of MAP kinase activity,GO:0043524~negative regulation of neuron apoptotic process,GO:0043589~skin morphogenesis,GO:0045893~positive regulation of transcription, DNA-templated,GO:0048167~regulation of synaptic plasticity,GO:0048538~thymus development,GO:0048666~neuron development,GO:0048705~skeletal system morphogenesis,GO:0048854~brain morphogenesis,GO:0050673~epithelial cell proliferation,GO:0050771~negative regulation of axonogenesis,GO:0050820~positive regulation of coagulation,GO:0050852~T cell receptor signaling pathway,GO:0051402~neuron apoptotic process,GO:0051444~negative regulation of ubiquitin-protein transferase activity,GO:0051563~smooth endoplasmic reticulum calcium ion homeostasis,GO:0051966~regulation of synaptic transmission, glutamatergic,GO:0060070~canonical Wnt signaling pathway,GO:0060075~regulation of resting membrane potential,GO:0060999~positive regulation of dendritic spine development,GO:0070588~calcium ion transmembrane transport,GO:2000059~negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process,GO:2001234~negative regulation of apoptotic signaling pathway,"]
[20,"FMR1","fragile X mental retardation 1(FMR1)","Homo sapiens",34,33,33.5,67,"GO:0000381~regulation of alternative mRNA splicing, via spliceosome,GO:0002092~positive regulation of receptor internalization,GO:0006397~mRNA processing,GO:0006974~cellular response to DNA damage stimulus,GO:0007215~glutamate receptor signaling pathway,GO:0008380~RNA splicing,GO:0017148~negative regulation of translation,GO:0031047~gene silencing by RNA,GO:0033129~positive regulation of histone phosphorylation,GO:0034644~cellular response to UV,GO:0043488~regulation of mRNA stability,GO:0044830~modulation by host of viral RNA genome replication,GO:0045727~positive regulation of translation,GO:0045947~negative regulation of translational initiation,GO:0046928~regulation of neurotransmitter secretion,GO:0051028~mRNA transport,GO:0051489~regulation of filopodium assembly,GO:0051491~positive regulation of filopodium assembly,GO:0060964~regulation of gene silencing by miRNA,GO:0060998~regulation of dendritic spine development,GO:0060999~positive regulation of dendritic spine development,GO:0072711~cellular response to hydroxyurea,GO:0098586~cellular response to virus,GO:0098908~regulation of neuronal action potential,GO:1900453~negative regulation of long term synaptic depression,GO:1901254~positive regulation of intracellular transport of viral material,GO:1901386~negative regulation of voltage-gated calcium channel activity,GO:1901800~positive regulation of proteasomal protein catabolic process,GO:1902416~positive regulation of mRNA binding,GO:2000301~negative regulation of synaptic vesicle exocytosis,GO:2000637~positive regulation of gene silencing by miRNA,GO:2000766~negative regulation of cytoplasmic translation,GO:2001022~positive regulation of response to DNA damage stimulus,","GO:0000381~regulation of alternative mRNA splicing, via spliceosome,GO:0002092~positive regulation of receptor internalization,GO:0006397~mRNA processing,GO:0006974~cellular response to DNA damage stimulus,GO:0007215~glutamate receptor signaling pathway,GO:0008380~RNA splicing,GO:0017148~negative regulation of translation,GO:0031047~gene silencing by RNA,GO:0033129~positive regulation of histone phosphorylation,GO:0034644~cellular response to UV,GO:0043488~regulation of mRNA stability,GO:0044830~modulation by host of viral RNA genome replication,GO:0045727~positive regulation of translation,GO:0045947~negative regulation of translational initiation,GO:0046928~regulation of neurotransmitter secretion,GO:0051028~mRNA transport,GO:0051489~regulation of filopodium assembly,GO:0051491~positive regulation of filopodium assembly,GO:0060964~regulation of gene silencing by miRNA,GO:0060998~regulation of dendritic spine development,GO:0060999~positive regulation of dendritic spine development,GO:0072711~cellular response to hydroxyurea,GO:0098586~cellular response to virus,GO:0098908~regulation of neuronal action potential,GO:1900453~negative regulation of long term synaptic depression,GO:1901254~positive regulation of intracellular transport of viral material,GO:1901386~negative regulation of voltage-gated calcium channel activity,GO:1901800~positive regulation of proteasomal protein catabolic process,GO:1902416~positive regulation of mRNA binding,GO:2000301~negative regulation of synaptic vesicle exocytosis,GO:2000637~positive regulation of gene silencing by miRNA,GO:2000766~negative regulation of cytoplasmic translation,GO:2001022~positive regulation of response to DNA damage stimulus,"]
[21,"IL2","interleukin 2(IL2)","Homo sapiens",33,33,33,66,"GO:0000165~MAPK cascade,GO:0001933~negative regulation of protein phosphorylation,GO:0002250~adaptive immune response,GO:0002903~negative regulation of B cell apoptotic process,GO:0006955~immune response,GO:0007155~cell adhesion,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007205~protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0007267~cell-cell signaling,GO:0008284~positive regulation of cell proliferation,GO:0030101~natural killer cell activation,GO:0030217~T cell differentiation,GO:0030307~positive regulation of cell growth,GO:0030890~positive regulation of B cell proliferation,GO:0032729~positive regulation of interferon-gamma production,GO:0032740~positive regulation of interleukin-17 production,GO:0034105~positive regulation of tissue remodeling,GO:0042104~positive regulation of activated T cell proliferation,GO:0042523~positive regulation of tyrosine phosphorylation of Stat5 protein,GO:0043066~negative regulation of apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0045471~response to ethanol,GO:0045591~positive regulation of regulatory T cell differentiation,GO:0045822~negative regulation of heart contraction,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046013~regulation of T cell homeostatic proliferation,GO:0048304~positive regulation of isotype switching to IgG isotypes,GO:0050672~negative regulation of lymphocyte proliferation,GO:0050728~negative regulation of inflammatory response,GO:0050729~positive regulation of inflammatory response,GO:0051024~positive regulation of immunoglobulin secretion,GO:0060999~positive regulation of dendritic spine development,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,","GO:0000165~MAPK cascade,GO:0001933~negative regulation of protein phosphorylation,GO:0002250~adaptive immune response,GO:0002903~negative regulation of B cell apoptotic process,GO:0006955~immune response,GO:0007155~cell adhesion,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007205~protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0007267~cell-cell signaling,GO:0008284~positive regulation of cell proliferation,GO:0030101~natural killer cell activation,GO:0030217~T cell differentiation,GO:0030307~positive regulation of cell growth,GO:0030890~positive regulation of B cell proliferation,GO:0032729~positive regulation of interferon-gamma production,GO:0032740~positive regulation of interleukin-17 production,GO:0034105~positive regulation of tissue remodeling,GO:0042104~positive regulation of activated T cell proliferation,GO:0042523~positive regulation of tyrosine phosphorylation of Stat5 protein,GO:0043066~negative regulation of apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0045471~response to ethanol,GO:0045591~positive regulation of regulatory T cell differentiation,GO:0045822~negative regulation of heart contraction,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046013~regulation of T cell homeostatic proliferation,GO:0048304~positive regulation of isotype switching to IgG isotypes,GO:0050672~negative regulation of lymphocyte proliferation,GO:0050728~negative regulation of inflammatory response,GO:0050729~positive regulation of inflammatory response,GO:0051024~positive regulation of immunoglobulin secretion,GO:0060999~positive regulation of dendritic spine development,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,"]
[22,"CHRNA7","cholinergic receptor nicotinic alpha 7 subunit(CHRNA7)","Homo sapiens",33,31,32,64,"GO:0000187~activation of MAPK activity,GO:0001666~response to hypoxia,GO:0001988~positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006874~cellular calcium ion homeostasis,GO:0006897~endocytosis,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007613~memory,GO:0008284~positive regulation of cell proliferation,GO:0008306~associative learning,GO:0014061~regulation of norepinephrine secretion,GO:0030317~sperm motility,GO:0032094~response to food,GO:0032225~regulation of synaptic transmission, dopaminergic,GO:0032691~negative regulation of interleukin-1 beta production,GO:0032715~negative regulation of interleukin-6 production,GO:0032720~negative regulation of tumor necrosis factor production,GO:0034220~ion transmembrane transport,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0042110~T cell activation,GO:0042113~B cell activation,GO:0042391~regulation of membrane potential,GO:0045766~positive regulation of angiogenesis,GO:0048149~behavioral response to ethanol,GO:0050728~negative regulation of inflammatory response,GO:0050890~cognition,GO:0060112~generation of ovulation cycle rhythm,GO:0098655~cation transmembrane transport,","GO:0000187~activation of MAPK activity,GO:0001666~response to hypoxia,GO:0001988~positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006874~cellular calcium ion homeostasis,GO:0006897~endocytosis,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007613~memory,GO:0008284~positive regulation of cell proliferation,GO:0008306~associative learning,GO:0014061~regulation of norepinephrine secretion,GO:0030317~sperm motility,GO:0032094~response to food,GO:0032225~regulation of synaptic transmission, dopaminergic,GO:0032691~negative regulation of interleukin-1 beta production,GO:0032715~negative regulation of interleukin-6 production,GO:0032720~negative regulation of tumor necrosis factor production,GO:0034220~ion transmembrane transport,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0042110~T cell activation,GO:0042113~B cell activation,GO:0042391~regulation of membrane potential,GO:0045766~positive regulation of angiogenesis,GO:0048149~behavioral response to ethanol,GO:0050728~negative regulation of inflammatory response,GO:0050890~cognition,GO:0060112~generation of ovulation cycle rhythm,GO:0098655~cation transmembrane transport,"]
[22,"ACE","angiotensin I converting enzyme(ACE)","Homo sapiens",32,32,32,64,"GO:0001822~kidney development,GO:0001974~blood vessel remodeling,GO:0002003~angiotensin maturation,GO:0002005~angiotensin catabolic process in blood,GO:0002019~regulation of renal output by angiotensin,GO:0002446~neutrophil mediated immunity,GO:0002474~antigen processing and presentation of peptide antigen via MHC class I,GO:0003081~regulation of systemic arterial blood pressure by renin-angiotensin,GO:0003084~positive regulation of systemic arterial blood pressure,GO:0007283~spermatogenesis,GO:0008217~regulation of blood pressure,GO:0010608~posttranscriptional regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0014910~regulation of smooth muscle cell migration,GO:0019229~regulation of vasoconstriction,GO:0032091~negative regulation of protein binding,GO:0032092~positive regulation of protein binding,GO:0032943~mononuclear cell proliferation,GO:0042312~regulation of vasodilation,GO:0042447~hormone catabolic process,GO:0043171~peptide catabolic process,GO:0050435~beta-amyloid metabolic process,GO:0050482~arachidonic acid secretion,GO:0060047~heart contraction,GO:0060177~regulation of angiotensin metabolic process,GO:0060218~hematopoietic stem cell differentiation,GO:0061098~positive regulation of protein tyrosine kinase activity,GO:0071838~cell proliferation in bone marrow,GO:1900086~positive regulation of peptidyl-tyrosine autophosphorylation,GO:1902033~regulation of hematopoietic stem cell proliferation,GO:1903597~negative regulation of gap junction assembly,GO:2000170~positive regulation of peptidyl-cysteine S-nitrosylation,","GO:0001822~kidney development,GO:0001974~blood vessel remodeling,GO:0002003~angiotensin maturation,GO:0002005~angiotensin catabolic process in blood,GO:0002019~regulation of renal output by angiotensin,GO:0002446~neutrophil mediated immunity,GO:0002474~antigen processing and presentation of peptide antigen via MHC class I,GO:0003081~regulation of systemic arterial blood pressure by renin-angiotensin,GO:0003084~positive regulation of systemic arterial blood pressure,GO:0007283~spermatogenesis,GO:0008217~regulation of blood pressure,GO:0010608~posttranscriptional regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0014910~regulation of smooth muscle cell migration,GO:0019229~regulation of vasoconstriction,GO:0032091~negative regulation of protein binding,GO:0032092~positive regulation of protein binding,GO:0032943~mononuclear cell proliferation,GO:0042312~regulation of vasodilation,GO:0042447~hormone catabolic process,GO:0043171~peptide catabolic process,GO:0050435~beta-amyloid metabolic process,GO:0050482~arachidonic acid secretion,GO:0060047~heart contraction,GO:0060177~regulation of angiotensin metabolic process,GO:0060218~hematopoietic stem cell differentiation,GO:0061098~positive regulation of protein tyrosine kinase activity,GO:0071838~cell proliferation in bone marrow,GO:1900086~positive regulation of peptidyl-tyrosine autophosphorylation,GO:1902033~regulation of hematopoietic stem cell proliferation,GO:1903597~negative regulation of gap junction assembly,GO:2000170~positive regulation of peptidyl-cysteine S-nitrosylation,"]
[23,"SOS1","SOS Ras/Rac guanine nucleotide exchange factor 1(SOS1)","Homo sapiens",31,31,31,62,"GO:0000165~MAPK cascade,GO:0001782~B cell homeostasis,GO:0001942~hair follicle development,GO:0003209~cardiac atrium morphogenesis,GO:0003344~pericardium morphogenesis,GO:0007165~signal transduction,GO:0007173~epidermal growth factor receptor signaling pathway,GO:0007264~small GTPase mediated signal transduction,GO:0007265~Ras protein signal transduction,GO:0007296~vitellogenesis,GO:0007411~axon guidance,GO:0008286~insulin receptor signaling pathway,GO:0033081~regulation of T cell differentiation in thymus,GO:0035023~regulation of Rho protein signal transduction,GO:0035264~multicellular organism growth,GO:0038095~Fc-epsilon receptor signaling pathway,GO:0038128~ERBB2 signaling pathway,GO:0042129~regulation of T cell proliferation,GO:0043065~positive regulation of apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0045742~positive regulation of epidermal growth factor receptor signaling pathway,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0048514~blood vessel morphogenesis,GO:0050900~leukocyte migration,GO:0051056~regulation of small GTPase mediated signal transduction,GO:0051057~positive regulation of small GTPase mediated signal transduction,GO:0060021~palate development,GO:0061029~eyelid development in camera-type eye,GO:0061384~heart trabecula morphogenesis,GO:1904693~midbrain morphogenesis,GO:2000973~regulation of pro-B cell differentiation,","GO:0000165~MAPK cascade,GO:0001782~B cell homeostasis,GO:0001942~hair follicle development,GO:0003209~cardiac atrium morphogenesis,GO:0003344~pericardium morphogenesis,GO:0007165~signal transduction,GO:0007173~epidermal growth factor receptor signaling pathway,GO:0007264~small GTPase mediated signal transduction,GO:0007265~Ras protein signal transduction,GO:0007296~vitellogenesis,GO:0007411~axon guidance,GO:0008286~insulin receptor signaling pathway,GO:0033081~regulation of T cell differentiation in thymus,GO:0035023~regulation of Rho protein signal transduction,GO:0035264~multicellular organism growth,GO:0038095~Fc-epsilon receptor signaling pathway,GO:0038128~ERBB2 signaling pathway,GO:0042129~regulation of T cell proliferation,GO:0043065~positive regulation of apoptotic process,GO:0043547~positive regulation of GTPase activity,GO:0045742~positive regulation of epidermal growth factor receptor signaling pathway,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0048514~blood vessel morphogenesis,GO:0050900~leukocyte migration,GO:0051056~regulation of small GTPase mediated signal transduction,GO:0051057~positive regulation of small GTPase mediated signal transduction,GO:0060021~palate development,GO:0061029~eyelid development in camera-type eye,GO:0061384~heart trabecula morphogenesis,GO:1904693~midbrain morphogenesis,GO:2000973~regulation of pro-B cell differentiation,"]
[24,"SOD1","superoxide dismutase 1, soluble(SOD1)","Homo sapiens",61,0,30.5,61,"GO:0000187~activation of MAPK activity,GO:0000302~response to reactive oxygen species,GO:0000303~response to superoxide,GO:0001541~ovarian follicle development,GO:0001819~positive regulation of cytokine production,GO:0001890~placenta development,GO:0001895~retina homeostasis,GO:0001975~response to amphetamine,GO:0002262~myeloid cell homeostasis,GO:0002576~platelet degranulation,GO:0006749~glutathione metabolic process,GO:0006801~superoxide metabolic process,GO:0006879~cellular iron ion homeostasis,GO:0007283~spermatogenesis,GO:0007566~embryo implantation,GO:0007568~aging,GO:0007569~cell aging,GO:0007605~sensory perception of sound,GO:0007626~locomotory behavior,GO:0008089~anterograde axonal transport,GO:0008090~retrograde axonal transport,GO:0008217~regulation of blood pressure,GO:0009408~response to heat,GO:0010033~response to organic substance,GO:0019226~transmission of nerve impulse,GO:0019430~removal of superoxide radicals,GO:0031667~response to nutrient levels,GO:0032287~peripheral nervous system myelin maintenance,GO:0032930~positive regulation of superoxide anion generation,GO:0033081~regulation of T cell differentiation in thymus,GO:0034465~response to carbon monoxide,GO:0035865~cellular response to potassium ion,GO:0040014~regulation of multicellular organism growth,GO:0042493~response to drug,GO:0042542~response to hydrogen peroxide,GO:0042554~superoxide anion generation,GO:0043065~positive regulation of apoptotic process,GO:0043085~positive regulation of catalytic activity,GO:0043087~regulation of GTPase activity,GO:0043524~negative regulation of neuron apoptotic process,GO:0045471~response to ethanol,GO:0045541~negative regulation of cholesterol biosynthetic process,GO:0045859~regulation of protein kinase activity,GO:0046620~regulation of organ growth,GO:0046677~response to antibiotic,GO:0046688~response to copper ion,GO:0046716~muscle cell cellular homeostasis,GO:0048538~thymus development,GO:0048678~response to axon injury,GO:0050665~hydrogen peroxide biosynthetic process,GO:0051881~regulation of mitochondrial membrane potential,GO:0055114~oxidation-reduction process,GO:0060047~heart contraction,GO:0060052~neurofilament cytoskeleton organization,GO:0060087~relaxation of vascular smooth muscle,GO:0060088~auditory receptor cell stereocilium organization,GO:0071276~cellular response to cadmium ion,GO:0071318~cellular response to ATP,GO:0072593~reactive oxygen species metabolic process,GO:0097332~response to antipsychotic drug,GO:1902177~positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway,"]
[25,"PAX6","paired box 6(PAX6)","Homo sapiens",60,0,30,60,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000132~establishment of mitotic spindle orientation,GO:0001568~blood vessel development,GO:0001654~eye development,GO:0001709~cell fate determination,GO:0001764~neuron migration,GO:0001933~negative regulation of protein phosphorylation,GO:0002052~positive regulation of neuroblast proliferation,GO:0002088~lens development in camera-type eye,GO:0003309~type B pancreatic cell differentiation,GO:0003322~pancreatic A cell development,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0007224~smoothened signaling pathway,GO:0007275~multicellular organism development,GO:0007411~axon guidance,GO:0007417~central nervous system development,GO:0007435~salivary gland morphogenesis,GO:0007601~visual perception,GO:0009611~response to wounding,GO:0009786~regulation of asymmetric cell division,GO:0009887~organ morphogenesis,GO:0009950~dorsal/ventral axis specification,GO:0010628~positive regulation of gene expression,GO:0016567~protein ubiquitination,GO:0021778~oligodendrocyte cell fate specification,GO:0021796~cerebral cortex regionalization,GO:0021798~forebrain dorsal/ventral pattern formation,GO:0021902~commitment of neuronal cell to specific neuron type in forebrain,GO:0021905~forebrain-midbrain boundary formation,GO:0021912~regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification,GO:0021913~regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification,GO:0021918~regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment,GO:0021983~pituitary gland development,GO:0021986~habenula development,GO:0023019~signal transduction involved in regulation of gene expression,GO:0030216~keratinocyte differentiation,GO:0030334~regulation of cell migration,GO:0030858~positive regulation of epithelial cell differentiation,GO:0032808~lacrimal gland development,GO:0033365~protein localization to organelle,GO:0042462~eye photoreceptor cell development,GO:0042593~glucose homeostasis,GO:0045665~negative regulation of neuron differentiation,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048505~regulation of timing of cell differentiation,GO:0048596~embryonic camera-type eye morphogenesis,GO:0048663~neuron fate commitment,GO:0048708~astrocyte differentiation,GO:0050680~negative regulation of epithelial cell proliferation,GO:0050768~negative regulation of neurogenesis,GO:0060041~retina development in camera-type eye,GO:0061072~iris morphogenesis,GO:0061303~cornea development in camera-type eye,GO:2000178~negative regulation of neural precursor cell proliferation,"]
[26,"DLG4","discs large MAGUK scaffold protein 4(DLG4)","Homo sapiens",28,28,28,56,"GO:0000165~MAPK cascade,GO:0002091~negative regulation of receptor internalization,GO:0006461~protein complex assembly,GO:0007165~signal transduction,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007268~chemical synaptic transmission,GO:0007399~nervous system development,GO:0007612~learning,GO:0016188~synaptic vesicle maturation,GO:0034220~ion transmembrane transport,GO:0035176~social behavior,GO:0035418~protein localization to synapse,GO:0035641~locomotory exploration behavior,GO:0043547~positive regulation of GTPase activity,GO:0045184~establishment of protein localization,GO:0045197~establishment or maintenance of epithelial cell apical/basal polarity,GO:0046037~GMP metabolic process,GO:0046710~GDP metabolic process,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0050806~positive regulation of synaptic transmission,GO:0050885~neuromuscular process controlling balance,GO:0060997~dendritic spine morphogenesis,GO:0071625~vocalization behavior,GO:0097113~AMPA glutamate receptor clustering,GO:0097120~receptor localization to synapse,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:2000463~positive regulation of excitatory postsynaptic potential,GO:2000821~regulation of grooming behavior,","GO:0000165~MAPK cascade,GO:0002091~negative regulation of receptor internalization,GO:0006461~protein complex assembly,GO:0007165~signal transduction,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007268~chemical synaptic transmission,GO:0007399~nervous system development,GO:0007612~learning,GO:0016188~synaptic vesicle maturation,GO:0034220~ion transmembrane transport,GO:0035176~social behavior,GO:0035418~protein localization to synapse,GO:0035641~locomotory exploration behavior,GO:0043547~positive regulation of GTPase activity,GO:0045184~establishment of protein localization,GO:0045197~establishment or maintenance of epithelial cell apical/basal polarity,GO:0046037~GMP metabolic process,GO:0046710~GDP metabolic process,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0050806~positive regulation of synaptic transmission,GO:0050885~neuromuscular process controlling balance,GO:0060997~dendritic spine morphogenesis,GO:0071625~vocalization behavior,GO:0097113~AMPA glutamate receptor clustering,GO:0097120~receptor localization to synapse,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:2000463~positive regulation of excitatory postsynaptic potential,GO:2000821~regulation of grooming behavior,"]
[27,"RAN","RAN, member RAS oncogene family(RAN)","Homo sapiens",28,26,27,54,"GO:0000055~ribosomal large subunit export from nucleus,GO:0000056~ribosomal small subunit export from nucleus,GO:0000060~protein import into nucleus, translocation,GO:0006259~DNA metabolic process,GO:0006409~tRNA export from nucleus,GO:0006606~protein import into nucleus,GO:0006611~protein export from nucleus,GO:0006886~intracellular protein transport,GO:0006913~nucleocytoplasmic transport,GO:0007052~mitotic spindle organization,GO:0007067~mitotic nuclear division,GO:0007165~signal transduction,GO:0007264~small GTPase mediated signal transduction,GO:0016032~viral process,GO:0030036~actin cytoskeleton organization,GO:0030521~androgen receptor signaling pathway,GO:0031047~gene silencing by RNA,GO:0032092~positive regulation of protein binding,GO:0034629~cellular protein complex localization,GO:0035281~pre-miRNA export from nucleus,GO:0045893~positive regulation of transcription, DNA-templated,GO:0051301~cell division,GO:0071806~protein transmembrane transport,GO:0075733~intracellular transport of virus,GO:0098609~cell-cell adhesion,GO:1902570~protein localization to nucleolus,","GO:0000055~ribosomal large subunit export from nucleus,GO:0000056~ribosomal small subunit export from nucleus,GO:0000060~protein import into nucleus, translocation,GO:0006259~DNA metabolic process,GO:0006409~tRNA export from nucleus,GO:0006606~protein import into nucleus,GO:0006611~protein export from nucleus,GO:0006886~intracellular protein transport,GO:0006913~nucleocytoplasmic transport,GO:0007052~mitotic spindle organization,GO:0007067~mitotic nuclear division,GO:0007165~signal transduction,GO:0007264~small GTPase mediated signal transduction,GO:0016032~viral process,GO:0030036~actin cytoskeleton organization,GO:0030521~androgen receptor signaling pathway,GO:0031047~gene silencing by RNA,GO:0032092~positive regulation of protein binding,GO:0034629~cellular protein complex localization,GO:0035281~pre-miRNA export from nucleus,GO:0045893~positive regulation of transcription, DNA-templated,GO:0051301~cell division,GO:0071806~protein transmembrane transport,GO:0075733~intracellular transport of virus,GO:0098609~cell-cell adhesion,GO:1902570~protein localization to nucleolus,"]
[28,"ICAM1","intercellular adhesion molecule 1(ICAM1)","Homo sapiens",53,0,26.5,53,"GO:0001541~ovarian follicle development,GO:0001910~regulation of leukocyte mediated cytotoxicity,GO:0001975~response to amphetamine,GO:0002291~T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell,GO:0002438~acute inflammatory response to antigenic stimulus,GO:0002457~T cell antigen processing and presentation,GO:0002693~positive regulation of cellular extravasation,GO:0007155~cell adhesion,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0007159~leukocyte cell-cell adhesion,GO:0007569~cell aging,GO:0007605~sensory perception of sound,GO:0008360~regulation of cell shape,GO:0010212~response to ionizing radiation,GO:0010477~response to sulfur dioxide,GO:0014070~response to organic cyclic compound,GO:0016337~single organismal cell-cell adhesion,GO:0022614~membrane to membrane docking,GO:0030155~regulation of cell adhesion,GO:0030198~extracellular matrix organization,GO:0030838~positive regulation of actin filament polymerization,GO:0031669~cellular response to nutrient levels,GO:0033627~cell adhesion mediated by integrin,GO:0034698~response to gonadotropin,GO:0042493~response to drug,GO:0043200~response to amino acid,GO:0043547~positive regulation of GTPase activity,GO:0044406~adhesion of symbiont to host,GO:0045429~positive regulation of nitric oxide biosynthetic process,GO:0045471~response to ethanol,GO:0045907~positive regulation of vasoconstriction,GO:0046688~response to copper ion,GO:0046718~viral entry into host cell,GO:0046813~receptor-mediated virion attachment to host cell,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0050776~regulation of immune response,GO:0050900~leukocyte migration,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051926~negative regulation of calcium ion transport,GO:0060333~interferon-gamma-mediated signaling pathway,GO:0061028~establishment of endothelial barrier,GO:0070234~positive regulation of T cell apoptotic process,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0071222~cellular response to lipopolysaccharide,GO:0071312~cellular response to alkaloid,GO:0071333~cellular response to glucose stimulus,GO:0071347~cellular response to interleukin-1,GO:0071356~cellular response to tumor necrosis factor,GO:0071456~cellular response to hypoxia,GO:0097368~establishment of Sertoli cell barrier,GO:1900027~regulation of ruffle assembly,GO:1902042~negative regulation of extrinsic apoptotic signaling pathway via death domain receptors,GO:2000352~negative regulation of endothelial cell apoptotic process,"]
[28,"DRD4","dopamine receptor D4(DRD4)","Homo sapiens",27,26,26.5,53,"GO:0000187~activation of MAPK activity,GO:0001662~behavioral fear response,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0006874~cellular calcium ion homeostasis,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007212~dopamine receptor signaling pathway,GO:0008344~adult locomotory behavior,GO:0030818~negative regulation of cAMP biosynthetic process,GO:0032417~positive regulation of sodium:proton antiporter activity,GO:0033674~positive regulation of kinase activity,GO:0034776~response to histamine,GO:0035176~social behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042417~dopamine metabolic process,GO:0042596~fear response,GO:0042752~regulation of circadian rhythm,GO:0048148~behavioral response to cocaine,GO:0048149~behavioral response to ethanol,GO:0048511~rhythmic process,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0051586~positive regulation of dopamine uptake involved in synaptic transmission,GO:0060080~inhibitory postsynaptic potential,GO:1901386~negative regulation of voltage-gated calcium channel activity,","GO:0000187~activation of MAPK activity,GO:0001662~behavioral fear response,GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0006874~cellular calcium ion homeostasis,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007195~adenylate cyclase-inhibiting dopamine receptor signaling pathway,GO:0007212~dopamine receptor signaling pathway,GO:0008344~adult locomotory behavior,GO:0030818~negative regulation of cAMP biosynthetic process,GO:0032417~positive regulation of sodium:proton antiporter activity,GO:0033674~positive regulation of kinase activity,GO:0034776~response to histamine,GO:0035176~social behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042417~dopamine metabolic process,GO:0042596~fear response,GO:0042752~regulation of circadian rhythm,GO:0048148~behavioral response to cocaine,GO:0048149~behavioral response to ethanol,GO:0048511~rhythmic process,GO:0050482~arachidonic acid secretion,GO:0050709~negative regulation of protein secretion,GO:0051586~positive regulation of dopamine uptake involved in synaptic transmission,GO:0060080~inhibitory postsynaptic potential,GO:1901386~negative regulation of voltage-gated calcium channel activity,"]
[28.999999999999996,"CRH","corticotropin releasing hormone(CRH)","Homo sapiens",52,0,26,52,"GO:0001934~positive regulation of protein phosphorylation,GO:0001963~synaptic transmission, dopaminergic,GO:0006704~glucocorticoid biosynthetic process,GO:0006954~inflammatory response,GO:0007165~signal transduction,GO:0007268~chemical synaptic transmission,GO:0007565~female pregnancy,GO:0007567~parturition,GO:0007611~learning or memory,GO:0008284~positive regulation of cell proliferation,GO:0008306~associative learning,GO:0008628~hormone-mediated apoptotic signaling pathway,GO:0010628~positive regulation of gene expression,GO:0010629~negative regulation of gene expression,GO:0010700~negative regulation of norepinephrine secretion,GO:0010841~positive regulation of circadian sleep/wake cycle, wakefulness,GO:0010942~positive regulation of cell death,GO:0014062~regulation of serotonin secretion,GO:0016101~diterpenoid metabolic process,GO:0021854~hypothalamus development,GO:0030324~lung development,GO:0030325~adrenal gland development,GO:0030819~positive regulation of cAMP biosynthetic process,GO:0032811~negative regulation of epinephrine secretion,GO:0033685~negative regulation of luteinizing hormone secretion,GO:0035641~locomotory exploration behavior,GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0035902~response to immobilization stress,GO:0042322~negative regulation of circadian sleep/wake cycle, REM sleep,GO:0042493~response to drug,GO:0043627~response to estrogen,GO:0045471~response to ethanol,GO:0045472~response to ether,GO:0045776~negative regulation of blood pressure,GO:0048265~response to pain,GO:0050801~ion homeostasis,GO:0051412~response to corticosterone,GO:0051461~positive regulation of corticotropin secretion,GO:0051464~positive regulation of cortisol secretion,GO:0060291~long-term synaptic potentiation,GO:0060456~positive regulation of digestive system process,GO:0060548~negative regulation of cell death,GO:0070093~negative regulation of glucagon secretion,GO:0071314~cellular response to cocaine,GO:0071549~cellular response to dexamethasone stimulus,GO:0090280~positive regulation of calcium ion import,GO:2000310~regulation of N-methyl-D-aspartate selective glutamate receptor activity,GO:2000854~positive regulation of corticosterone secretion,GO:2000987~positive regulation of behavioral fear response,"]
[28.999999999999996,"PTPN11","protein tyrosine phosphatase, non-receptor type 11(PTPN11)","Homo sapiens",52,0,26,52,"GO:0000077~DNA damage checkpoint,GO:0000187~activation of MAPK activity,GO:0006641~triglyceride metabolic process,GO:0007173~epidermal growth factor receptor signaling pathway,GO:0007229~integrin-mediated signaling pathway,GO:0007409~axonogenesis,GO:0007420~brain development,GO:0007507~heart development,GO:0008543~fibroblast growth factor receptor signaling pathway,GO:0009755~hormone-mediated signaling pathway,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0021697~cerebellar cortex formation,GO:0030168~platelet activation,GO:0030220~platelet formation,GO:0031295~T cell costimulation,GO:0032528~microvillus organization,GO:0033277~abortive mitotic cell cycle,GO:0033628~regulation of cell adhesion mediated by integrin,GO:0033629~negative regulation of cell adhesion mediated by integrin,GO:0035264~multicellular organism growth,GO:0035265~organ growth,GO:0035335~peptidyl-tyrosine dephosphorylation,GO:0035855~megakaryocyte development,GO:0036092~phosphatidylinositol-3-phosphate biosynthetic process,GO:0036302~atrioventricular canal development,GO:0038127~ERBB signaling pathway,GO:0040014~regulation of multicellular organism growth,GO:0042445~hormone metabolic process,GO:0042593~glucose homeostasis,GO:0043254~regulation of protein complex assembly,GO:0045931~positive regulation of mitotic cell cycle,GO:0046676~negative regulation of insulin secretion,GO:0046825~regulation of protein export from nucleus,GO:0046854~phosphatidylinositol phosphorylation,GO:0046887~positive regulation of hormone secretion,GO:0048008~platelet-derived growth factor receptor signaling pathway,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0048013~ephrin receptor signaling pathway,GO:0048015~phosphatidylinositol-mediated signaling,GO:0048609~multicellular organismal reproductive process,GO:0048806~genitalia development,GO:0048839~inner ear development,GO:0048873~homeostasis of number of cells within a tissue,GO:0050900~leukocyte migration,GO:0051463~negative regulation of cortisol secretion,GO:0060020~Bergmann glial cell differentiation,GO:0060125~negative regulation of growth hormone secretion,GO:0060325~face morphogenesis,GO:0060338~regulation of type I interferon-mediated signaling pathway,GO:0061582~intestinal epithelial cell migration,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:2001275~positive regulation of glucose import in response to insulin stimulus,"]
[28.999999999999996,"ABAT","4-aminobutyrate aminotransferase(ABAT)","Homo sapiens",26,26,26,52,"GO:0001666~response to hypoxia,GO:0007568~aging,GO:0007620~copulation,GO:0007626~locomotory behavior,GO:0009448~gamma-aminobutyric acid metabolic process,GO:0009449~gamma-aminobutyric acid biosynthetic process,GO:0009450~gamma-aminobutyric acid catabolic process,GO:0010039~response to iron ion,GO:0014053~negative regulation of gamma-aminobutyric acid secretion,GO:0021549~cerebellum development,GO:0031652~positive regulation of heat generation,GO:0032024~positive regulation of insulin secretion,GO:0033602~negative regulation of dopamine secretion,GO:0035094~response to nicotine,GO:0035640~exploration behavior,GO:0042135~neurotransmitter catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0045776~negative regulation of blood pressure,GO:0045964~positive regulation of dopamine metabolic process,GO:0048148~behavioral response to cocaine,GO:0070474~positive regulation of uterine smooth muscle contraction,GO:0090331~negative regulation of platelet aggregation,GO:0097151~positive regulation of inhibitory postsynaptic potential,GO:1902722~positive regulation of prolactin secretion,GO:1904450~positive regulation of aspartate secretion,","GO:0001666~response to hypoxia,GO:0007568~aging,GO:0007620~copulation,GO:0007626~locomotory behavior,GO:0009448~gamma-aminobutyric acid metabolic process,GO:0009449~gamma-aminobutyric acid biosynthetic process,GO:0009450~gamma-aminobutyric acid catabolic process,GO:0010039~response to iron ion,GO:0014053~negative regulation of gamma-aminobutyric acid secretion,GO:0021549~cerebellum development,GO:0031652~positive regulation of heat generation,GO:0032024~positive regulation of insulin secretion,GO:0033602~negative regulation of dopamine secretion,GO:0035094~response to nicotine,GO:0035640~exploration behavior,GO:0042135~neurotransmitter catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0045776~negative regulation of blood pressure,GO:0045964~positive regulation of dopamine metabolic process,GO:0048148~behavioral response to cocaine,GO:0070474~positive regulation of uterine smooth muscle contraction,GO:0090331~negative regulation of platelet aggregation,GO:0097151~positive regulation of inhibitory postsynaptic potential,GO:1902722~positive regulation of prolactin secretion,GO:1904450~positive regulation of aspartate secretion,"]
[29.999999999999996,"CHRNA4","cholinergic receptor nicotinic alpha 4 subunit(CHRNA4)","Homo sapiens",26,25,25.5,51,"GO:0001508~action potential,GO:0001666~response to hypoxia,GO:0006281~DNA repair,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006979~response to oxidative stress,GO:0007165~signal transduction,GO:0007268~chemical synaptic transmission,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0007585~respiratory gaseous exchange,GO:0007626~locomotory behavior,GO:0014059~regulation of dopamine secretion,GO:0019233~sensory perception of pain,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0035640~exploration behavior,GO:0042113~B cell activation,GO:0042391~regulation of membrane potential,GO:0050877~neurological system process,GO:0050890~cognition,GO:0051899~membrane depolarization,GO:0060080~inhibitory postsynaptic potential,GO:0095500~acetylcholine receptor signaling pathway,GO:0098655~cation transmembrane transport,","GO:0001508~action potential,GO:0001666~response to hypoxia,GO:0006281~DNA repair,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006979~response to oxidative stress,GO:0007165~signal transduction,GO:0007268~chemical synaptic transmission,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0007585~respiratory gaseous exchange,GO:0007626~locomotory behavior,GO:0014059~regulation of dopamine secretion,GO:0019233~sensory perception of pain,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0035640~exploration behavior,GO:0042113~B cell activation,GO:0042391~regulation of membrane potential,GO:0050877~neurological system process,GO:0050890~cognition,GO:0051899~membrane depolarization,GO:0060080~inhibitory postsynaptic potential,GO:0095500~acetylcholine receptor signaling pathway,GO:0098655~cation transmembrane transport,"]
[30.999999999999996,"PAFAH1B1","platelet activating factor acetylhydrolase 1b regulatory subunit 1(PAFAH1B1)","Homo sapiens",50,0,25,50,"GO:0000086~G2/M transition of mitotic cell cycle,GO:0000132~establishment of mitotic spindle orientation,GO:0000226~microtubule cytoskeleton organization,GO:0001667~ameboidal-type cell migration,GO:0001675~acrosome assembly,GO:0001764~neuron migration,GO:0001961~positive regulation of cytokine-mediated signaling pathway,GO:0007017~microtubule-based process,GO:0007062~sister chromatid cohesion,GO:0007067~mitotic nuclear division,GO:0007097~nuclear migration,GO:0007268~chemical synaptic transmission,GO:0007281~germ cell development,GO:0007405~neuroblast proliferation,GO:0007611~learning or memory,GO:0008090~retrograde axonal transport,GO:0008344~adult locomotory behavior,GO:0009306~protein secretion,GO:0010977~negative regulation of neuron projection development,GO:0016042~lipid catabolic process,GO:0017145~stem cell division,GO:0019226~transmission of nerve impulse,GO:0021540~corpus callosum morphogenesis,GO:0021766~hippocampus development,GO:0021819~layer formation in cerebral cortex,GO:0021895~cerebral cortex neuron differentiation,GO:0021987~cerebral cortex development,GO:0030036~actin cytoskeleton organization,GO:0031023~microtubule organizing center organization,GO:0036035~osteoclast development,GO:0040019~positive regulation of embryonic development,GO:0042249~establishment of planar polarity of embryonic epithelium,GO:0043087~regulation of GTPase activity,GO:0043622~cortical microtubule organization,GO:0045773~positive regulation of axon extension,GO:0045931~positive regulation of mitotic cell cycle,GO:0046329~negative regulation of JNK cascade,GO:0046469~platelet activating factor metabolic process,GO:0047496~vesicle transport along microtubule,GO:0048854~brain morphogenesis,GO:0050885~neuromuscular process controlling balance,GO:0051081~nuclear envelope disassembly,GO:0051660~establishment of centrosome localization,GO:0051661~maintenance of centrosome location,GO:0060117~auditory receptor cell development,GO:0061003~positive regulation of dendritic spine morphogenesis,GO:0070507~regulation of microtubule cytoskeleton organization,GO:0090102~cochlea development,GO:0090176~microtubule cytoskeleton organization involved in establishment of planar polarity,GO:2000574~regulation of microtubule motor activity,"]
[30.999999999999996,"CDH2","cadherin 2(CDH2)","Homo sapiens",25,25,25,50,"GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0009966~regulation of signal transduction,GO:0010001~glial cell differentiation,GO:0016339~calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0016477~cell migration,GO:0021987~cerebral cortex development,GO:0034332~adherens junction organization,GO:0043410~positive regulation of MAPK cascade,GO:0044331~cell-cell adhesion mediated by cadherin,GO:0048514~blood vessel morphogenesis,GO:0048854~brain morphogenesis,GO:0048872~homeostasis of number of cells,GO:0051146~striated muscle cell differentiation,GO:0051149~positive regulation of muscle cell differentiation,GO:0060019~radial glial cell differentiation,GO:0060563~neuroepithelial cell differentiation,GO:0070445~regulation of oligodendrocyte progenitor proliferation,GO:0090002~establishment of protein localization to plasma membrane,GO:0090090~negative regulation of canonical Wnt signaling pathway,GO:0097118~neuroligin clustering involved in postsynaptic membrane assembly,GO:0097150~neuronal stem cell population maintenance,GO:1902897~regulation of postsynaptic density protein 95 clustering,GO:2000809~positive regulation of synaptic vesicle clustering,","GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0009966~regulation of signal transduction,GO:0010001~glial cell differentiation,GO:0016339~calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0016477~cell migration,GO:0021987~cerebral cortex development,GO:0034332~adherens junction organization,GO:0043410~positive regulation of MAPK cascade,GO:0044331~cell-cell adhesion mediated by cadherin,GO:0048514~blood vessel morphogenesis,GO:0048854~brain morphogenesis,GO:0048872~homeostasis of number of cells,GO:0051146~striated muscle cell differentiation,GO:0051149~positive regulation of muscle cell differentiation,GO:0060019~radial glial cell differentiation,GO:0060563~neuroepithelial cell differentiation,GO:0070445~regulation of oligodendrocyte progenitor proliferation,GO:0090002~establishment of protein localization to plasma membrane,GO:0090090~negative regulation of canonical Wnt signaling pathway,GO:0097118~neuroligin clustering involved in postsynaptic membrane assembly,GO:0097150~neuronal stem cell population maintenance,GO:1902897~regulation of postsynaptic density protein 95 clustering,GO:2000809~positive regulation of synaptic vesicle clustering,"]
[31.999999999999996,"DRD5","dopamine receptor D5(DRD5)","Homo sapiens",25,24,24.5,49,"GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0001992~regulation of systemic arterial blood pressure by vasopressin,GO:0001994~norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure,GO:0006874~cellular calcium ion homeostasis,GO:0007189~adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0007190~activation of adenylate cyclase activity,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007612~learning,GO:0008306~associative learning,GO:0010579~positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway,GO:0019226~transmission of nerve impulse,GO:0033861~negative regulation of NAD(P)H oxidase activity,GO:0042060~wound healing,GO:0042220~response to cocaine,GO:0045762~positive regulation of adenylate cyclase activity,GO:0045776~negative regulation of blood pressure,GO:0045924~regulation of female receptivity,GO:0046960~sensitization,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060292~long term synaptic depression,GO:0071870~cellular response to catecholamine stimulus,GO:0072593~reactive oxygen species metabolic process,","GO:0001963~synaptic transmission, dopaminergic,GO:0001975~response to amphetamine,GO:0001992~regulation of systemic arterial blood pressure by vasopressin,GO:0001994~norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure,GO:0006874~cellular calcium ion homeostasis,GO:0007189~adenylate cyclase-activating G-protein coupled receptor signaling pathway,GO:0007190~activation of adenylate cyclase activity,GO:0007191~adenylate cyclase-activating dopamine receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007612~learning,GO:0008306~associative learning,GO:0010579~positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway,GO:0019226~transmission of nerve impulse,GO:0033861~negative regulation of NAD(P)H oxidase activity,GO:0042060~wound healing,GO:0042220~response to cocaine,GO:0045762~positive regulation of adenylate cyclase activity,GO:0045776~negative regulation of blood pressure,GO:0045924~regulation of female receptivity,GO:0046960~sensitization,GO:0060158~phospholipase C-activating dopamine receptor signaling pathway,GO:0060292~long term synaptic depression,GO:0071870~cellular response to catecholamine stimulus,GO:0072593~reactive oxygen species metabolic process,"]
[33,"KITLG","KIT ligand(KITLG)","Homo sapiens",24,24,24,48,"GO:0000165~MAPK cascade,GO:0001541~ovarian follicle development,GO:0001755~neural crest cell migration,GO:0002687~positive regulation of leukocyte migration,GO:0002763~positive regulation of myeloid leukocyte differentiation,GO:0007155~cell adhesion,GO:0007165~signal transduction,GO:0008283~cell proliferation,GO:0008584~male gonad development,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0033026~negative regulation of mast cell apoptotic process,GO:0035162~embryonic hemopoiesis,GO:0035234~ectopic germ cell programmed cell death,GO:0043406~positive regulation of MAP kinase activity,GO:0043547~positive regulation of GTPase activity,GO:0045636~positive regulation of melanocyte differentiation,GO:0045740~positive regulation of DNA replication,GO:0046579~positive regulation of Ras protein signal transduction,GO:0046854~phosphatidylinositol phosphorylation,GO:0048015~phosphatidylinositol-mediated signaling,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0070668~positive regulation of mast cell proliferation,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,GO:1902035~positive regulation of hematopoietic stem cell proliferation,","GO:0000165~MAPK cascade,GO:0001541~ovarian follicle development,GO:0001755~neural crest cell migration,GO:0002687~positive regulation of leukocyte migration,GO:0002763~positive regulation of myeloid leukocyte differentiation,GO:0007155~cell adhesion,GO:0007165~signal transduction,GO:0008283~cell proliferation,GO:0008584~male gonad development,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0033026~negative regulation of mast cell apoptotic process,GO:0035162~embryonic hemopoiesis,GO:0035234~ectopic germ cell programmed cell death,GO:0043406~positive regulation of MAP kinase activity,GO:0043547~positive regulation of GTPase activity,GO:0045636~positive regulation of melanocyte differentiation,GO:0045740~positive regulation of DNA replication,GO:0046579~positive regulation of Ras protein signal transduction,GO:0046854~phosphatidylinositol phosphorylation,GO:0048015~phosphatidylinositol-mediated signaling,GO:0050731~positive regulation of peptidyl-tyrosine phosphorylation,GO:0070668~positive regulation of mast cell proliferation,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,GO:1902035~positive regulation of hematopoietic stem cell proliferation,"]
[33,"CDH13","cadherin 13(CDH13)","Homo sapiens",24,24,24,48,"GO:0000278~mitotic cell cycle,GO:0001938~positive regulation of endothelial cell proliferation,GO:0001954~positive regulation of cell-matrix adhesion,GO:0002040~sprouting angiogenesis,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007162~negative regulation of cell adhesion,GO:0007266~Rho protein signal transduction,GO:0008285~negative regulation of cell proliferation,GO:0016339~calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0016601~Rac protein signal transduction,GO:0030032~lamellipodium assembly,GO:0030100~regulation of endocytosis,GO:0030335~positive regulation of cell migration,GO:0034332~adherens junction organization,GO:0042058~regulation of epidermal growth factor receptor signaling pathway,GO:0043542~endothelial cell migration,GO:0043616~keratinocyte proliferation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050850~positive regulation of calcium-mediated signaling,GO:0050927~positive regulation of positive chemotaxis,GO:0051668~localization within membrane,GO:0055096~low-density lipoprotein particle mediated signaling,","GO:0000278~mitotic cell cycle,GO:0001938~positive regulation of endothelial cell proliferation,GO:0001954~positive regulation of cell-matrix adhesion,GO:0002040~sprouting angiogenesis,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007162~negative regulation of cell adhesion,GO:0007266~Rho protein signal transduction,GO:0008285~negative regulation of cell proliferation,GO:0016339~calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0016601~Rac protein signal transduction,GO:0030032~lamellipodium assembly,GO:0030100~regulation of endocytosis,GO:0030335~positive regulation of cell migration,GO:0034332~adherens junction organization,GO:0042058~regulation of epidermal growth factor receptor signaling pathway,GO:0043542~endothelial cell migration,GO:0043616~keratinocyte proliferation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048661~positive regulation of smooth muscle cell proliferation,GO:0050850~positive regulation of calcium-mediated signaling,GO:0050927~positive regulation of positive chemotaxis,GO:0051668~localization within membrane,GO:0055096~low-density lipoprotein particle mediated signaling,"]
[34,"PER1","period circadian clock 1(PER1)","Homo sapiens",24,22,23,46,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0002028~regulation of sodium ion transport,GO:0006351~transcription, DNA-templated,GO:0007623~circadian rhythm,GO:0009649~entrainment of circadian clock,GO:0010608~posttranscriptional regulation of gene expression,GO:0032922~circadian regulation of gene expression,GO:0042634~regulation of hair cycle,GO:0042752~regulation of circadian rhythm,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043153~entrainment of circadian clock by photoperiod,GO:0043966~histone H3 acetylation,GO:0043967~histone H4 acetylation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046329~negative regulation of JNK cascade,GO:0051591~response to cAMP,GO:0070932~histone H3 deacetylation,GO:0097167~circadian regulation of translation,GO:1900015~regulation of cytokine production involved in inflammatory response,GO:1900744~regulation of p38MAPK cascade,GO:2000323~negative regulation of glucocorticoid receptor signaling pathway,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0002028~regulation of sodium ion transport,GO:0006351~transcription, DNA-templated,GO:0007623~circadian rhythm,GO:0009649~entrainment of circadian clock,GO:0010608~posttranscriptional regulation of gene expression,GO:0032922~circadian regulation of gene expression,GO:0042634~regulation of hair cycle,GO:0042752~regulation of circadian rhythm,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0043153~entrainment of circadian clock by photoperiod,GO:0043966~histone H3 acetylation,GO:0043967~histone H4 acetylation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046329~negative regulation of JNK cascade,GO:0051591~response to cAMP,GO:0070932~histone H3 deacetylation,GO:0097167~circadian regulation of translation,GO:1900015~regulation of cytokine production involved in inflammatory response,GO:1900744~regulation of p38MAPK cascade,GO:2000323~negative regulation of glucocorticoid receptor signaling pathway,"]
[35,"SLC6A3","solute carrier family 6 member 3(SLC6A3)","Homo sapiens",22,22,22,44,"GO:0007568~aging,GO:0007595~lactation,GO:0007608~sensory perception of smell,GO:0007626~locomotory behavior,GO:0010039~response to iron ion,GO:0015844~monoamine transport,GO:0015872~dopamine transport,GO:0021984~adenohypophysis development,GO:0035094~response to nicotine,GO:0040018~positive regulation of multicellular organism growth,GO:0042053~regulation of dopamine metabolic process,GO:0042136~neurotransmitter biosynthetic process,GO:0042220~response to cocaine,GO:0042416~dopamine biosynthetic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0051583~dopamine uptake involved in synaptic transmission,GO:0051591~response to cAMP,GO:0055085~transmembrane transport,GO:0060134~prepulse inhibition,GO:0090494~dopamine uptake,","GO:0007568~aging,GO:0007595~lactation,GO:0007608~sensory perception of smell,GO:0007626~locomotory behavior,GO:0010039~response to iron ion,GO:0015844~monoamine transport,GO:0015872~dopamine transport,GO:0021984~adenohypophysis development,GO:0035094~response to nicotine,GO:0040018~positive regulation of multicellular organism growth,GO:0042053~regulation of dopamine metabolic process,GO:0042136~neurotransmitter biosynthetic process,GO:0042220~response to cocaine,GO:0042416~dopamine biosynthetic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0051583~dopamine uptake involved in synaptic transmission,GO:0051591~response to cAMP,GO:0055085~transmembrane transport,GO:0060134~prepulse inhibition,GO:0090494~dopamine uptake,"]
[36,"CACNA1A","calcium voltage-gated channel subunit alpha1 A(CACNA1A)","Homo sapiens",41,0,20.5,41,"GO:0000096~sulfur amino acid metabolic process,GO:0006006~glucose metabolic process,GO:0006816~calcium ion transport,GO:0007204~positive regulation of cytosolic calcium ion concentration,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0007274~neuromuscular synaptic transmission,GO:0007416~synapse assembly,GO:0007628~adult walking behavior,GO:0008219~cell death,GO:0014051~gamma-aminobutyric acid secretion,GO:0014056~regulation of acetylcholine secretion, neurotransmission,GO:0016049~cell growth,GO:0017158~regulation of calcium ion-dependent exocytosis,GO:0019226~transmission of nerve impulse,GO:0021522~spinal cord motor neuron differentiation,GO:0021590~cerebellum maturation,GO:0021679~cerebellar molecular layer development,GO:0021702~cerebellar Purkinje cell differentiation,GO:0021750~vestibular nucleus development,GO:0030644~cellular chloride ion homeostasis,GO:0032353~negative regulation of hormone biosynthetic process,GO:0034765~regulation of ion transmembrane transport,GO:0035249~synaptic transmission, glutamatergic,GO:0042133~neurotransmitter metabolic process,GO:0042445~hormone metabolic process,GO:0043113~receptor clustering,GO:0043524~negative regulation of neuron apoptotic process,GO:0048266~behavioral response to pain,GO:0048791~calcium ion-regulated exocytosis of neurotransmitter,GO:0048813~dendrite morphogenesis,GO:0050770~regulation of axonogenesis,GO:0050796~regulation of insulin secretion,GO:0050883~musculoskeletal movement, spinal reflex action,GO:0050885~neuromuscular process controlling balance,GO:0051899~membrane depolarization,GO:0060024~rhythmic synaptic transmission,GO:0070588~calcium ion transmembrane transport,GO:0086010~membrane depolarization during action potential,"]
[37.00000000000001,"TSPO","translocator protein(TSPO)","Homo sapiens",40,0,20,40,"GO:0006626~protein targeting to mitochondrion,GO:0006694~steroid biosynthetic process,GO:0006783~heme biosynthetic process,GO:0006820~anion transport,GO:0006821~chloride transport,GO:0006869~lipid transport,GO:0006915~apoptotic process,GO:0007165~signal transduction,GO:0007568~aging,GO:0008202~steroid metabolic process,GO:0008283~cell proliferation,GO:0008347~glial cell migration,GO:0010042~response to manganese ion,GO:0010266~response to vitamin B1,GO:0010940~positive regulation of necrotic cell death,GO:0014012~peripheral nervous system axon regeneration,GO:0030325~adrenal gland development,GO:0031397~negative regulation of protein ubiquitination,GO:0032374~regulation of cholesterol transport,GO:0032570~response to progesterone,GO:0032720~negative regulation of tumor necrosis factor production,GO:0033574~response to testosterone,GO:0042493~response to drug,GO:0043065~positive regulation of apoptotic process,GO:0045019~negative regulation of nitric oxide biosynthetic process,GO:0048266~behavioral response to pain,GO:0050810~regulation of steroid biosynthetic process,GO:0051901~positive regulation of mitochondrial depolarization,GO:0051928~positive regulation of calcium ion transport,GO:0060242~contact inhibition,GO:0060252~positive regulation of glial cell proliferation,GO:0060253~negative regulation of glial cell proliferation,GO:0071222~cellular response to lipopolysaccharide,GO:0071294~cellular response to zinc ion,GO:0071476~cellular hypotonic response,GO:0072655~establishment of protein localization to mitochondrion,GO:0072656~maintenance of protein location in mitochondrion,GO:1903147~negative regulation of mitophagy,GO:1903579~negative regulation of ATP metabolic process,GO:2000379~positive regulation of reactive oxygen species metabolic process,"]
[37.00000000000001,"COMT","catechol-O-methyltransferase(COMT)","Homo sapiens",20,20,20,40,"GO:0006584~catecholamine metabolic process,GO:0007565~female pregnancy,GO:0007612~learning,GO:0007614~short-term memory,GO:0008210~estrogen metabolic process,GO:0014070~response to organic cyclic compound,GO:0016036~cellular response to phosphate starvation,GO:0032259~methylation,GO:0032496~response to lipopolysaccharide,GO:0032502~developmental process,GO:0035814~negative regulation of renal sodium excretion,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045963~negative regulation of dopamine metabolic process,GO:0048265~response to pain,GO:0048609~multicellular organismal reproductive process,GO:0048662~negative regulation of smooth muscle cell proliferation,GO:0050668~positive regulation of homocysteine metabolic process,GO:0051930~regulation of sensory perception of pain,","GO:0006584~catecholamine metabolic process,GO:0007565~female pregnancy,GO:0007612~learning,GO:0007614~short-term memory,GO:0008210~estrogen metabolic process,GO:0014070~response to organic cyclic compound,GO:0016036~cellular response to phosphate starvation,GO:0032259~methylation,GO:0032496~response to lipopolysaccharide,GO:0032502~developmental process,GO:0035814~negative regulation of renal sodium excretion,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045963~negative regulation of dopamine metabolic process,GO:0048265~response to pain,GO:0048609~multicellular organismal reproductive process,GO:0048662~negative regulation of smooth muscle cell proliferation,GO:0050668~positive regulation of homocysteine metabolic process,GO:0051930~regulation of sensory perception of pain,"]
[37.00000000000001,"HLA-DRB1","major histocompatibility complex, class II, DR beta 1(HLA-DRB1)","Homo sapiens",20,20,20,40,"GO:0002381~immunoglobulin production involved in immunoglobulin mediated immune response,GO:0002437~inflammatory response to antigenic stimulus,GO:0002455~humoral immune response mediated by circulating immunoglobulin,GO:0002503~peptide antigen assembly with MHC class II protein complex,GO:0002504~antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,GO:0002506~polysaccharide assembly with MHC class II protein complex,GO:0006955~immune response,GO:0016045~detection of bacterium,GO:0019882~antigen processing and presentation,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0031295~T cell costimulation,GO:0032673~regulation of interleukin-4 production,GO:0032689~negative regulation of interferon-gamma production,GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0042088~T-helper 1 type immune response,GO:0042130~negative regulation of T cell proliferation,GO:0050852~T cell receptor signaling pathway,GO:0051262~protein tetramerization,GO:0060333~interferon-gamma-mediated signaling pathway,GO:2001179~regulation of interleukin-10 secretion,","GO:0002381~immunoglobulin production involved in immunoglobulin mediated immune response,GO:0002437~inflammatory response to antigenic stimulus,GO:0002455~humoral immune response mediated by circulating immunoglobulin,GO:0002503~peptide antigen assembly with MHC class II protein complex,GO:0002504~antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,GO:0002506~polysaccharide assembly with MHC class II protein complex,GO:0006955~immune response,GO:0016045~detection of bacterium,GO:0019882~antigen processing and presentation,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0031295~T cell costimulation,GO:0032673~regulation of interleukin-4 production,GO:0032689~negative regulation of interferon-gamma production,GO:0035774~positive regulation of insulin secretion involved in cellular response to glucose stimulus,GO:0042088~T-helper 1 type immune response,GO:0042130~negative regulation of T cell proliferation,GO:0050852~T cell receptor signaling pathway,GO:0051262~protein tetramerization,GO:0060333~interferon-gamma-mediated signaling pathway,GO:2001179~regulation of interleukin-10 secretion,"]
[38.00000000000001,"FOXP2","forkhead box P2(FOXP2)","Homo sapiens",19,17,18,36,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0002053~positive regulation of mesenchymal cell proliferation,GO:0006351~transcription, DNA-templated,GO:0007519~skeletal muscle tissue development,GO:0009791~post-embryonic development,GO:0021549~cerebellum development,GO:0021757~caudate nucleus development,GO:0021758~putamen development,GO:0021987~cerebral cortex development,GO:0040007~growth,GO:0042297~vocal learning,GO:0043010~camera-type eye development,GO:0045892~negative regulation of transcription, DNA-templated,GO:0048286~lung alveolus development,GO:0048745~smooth muscle tissue development,GO:0060013~righting reflex,GO:0060501~positive regulation of epithelial cell proliferation involved in lung morphogenesis,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0002053~positive regulation of mesenchymal cell proliferation,GO:0006351~transcription, DNA-templated,GO:0007519~skeletal muscle tissue development,GO:0009791~post-embryonic development,GO:0021549~cerebellum development,GO:0021757~caudate nucleus development,GO:0021758~putamen development,GO:0021987~cerebral cortex development,GO:0040007~growth,GO:0042297~vocal learning,GO:0043010~camera-type eye development,GO:0045892~negative regulation of transcription, DNA-templated,GO:0048286~lung alveolus development,GO:0048745~smooth muscle tissue development,GO:0060013~righting reflex,GO:0060501~positive regulation of epithelial cell proliferation involved in lung morphogenesis,"]
[38.00000000000001,"SLC6A1","solute carrier family 6 member 1(SLC6A1)","Homo sapiens",18,18,18,36,"GO:0006810~transport,GO:0006836~neurotransmitter transport,GO:0007268~chemical synaptic transmission,GO:0007612~learning,GO:0009636~response to toxic substance,GO:0009744~response to sucrose,GO:0010288~response to lead ion,GO:0014054~positive regulation of gamma-aminobutyric acid secretion,GO:0014074~response to purine-containing compound,GO:0015812~gamma-aminobutyric acid transport,GO:0032229~negative regulation of synaptic transmission, GABAergic,GO:0032355~response to estradiol,GO:0042220~response to cocaine,GO:0051260~protein homooligomerization,GO:0051592~response to calcium ion,GO:0051939~gamma-aminobutyric acid import,GO:0055085~transmembrane transport,","GO:0006810~transport,GO:0006836~neurotransmitter transport,GO:0007268~chemical synaptic transmission,GO:0007612~learning,GO:0009636~response to toxic substance,GO:0009744~response to sucrose,GO:0010288~response to lead ion,GO:0014054~positive regulation of gamma-aminobutyric acid secretion,GO:0014074~response to purine-containing compound,GO:0015812~gamma-aminobutyric acid transport,GO:0032229~negative regulation of synaptic transmission, GABAergic,GO:0032355~response to estradiol,GO:0042220~response to cocaine,GO:0051260~protein homooligomerization,GO:0051592~response to calcium ion,GO:0051939~gamma-aminobutyric acid import,GO:0055085~transmembrane transport,"]
[39.00000000000001,"RAF1","Raf-1 proto-oncogene, serine/threonine kinase(RAF1)","Homo sapiens",35,0,17.5,35,"GO:0000165~MAPK cascade,GO:0000186~activation of MAPKK activity,GO:0001666~response to hypoxia,GO:0002223~stimulatory C-type lectin receptor signaling pathway,GO:0006468~protein phosphorylation,GO:0006915~apoptotic process,GO:0007165~signal transduction,GO:0007190~activation of adenylate cyclase activity,GO:0007507~heart development,GO:0008283~cell proliferation,GO:0008285~negative regulation of cell proliferation,GO:0030154~cell differentiation,GO:0030168~platelet activation,GO:0030878~thyroid gland development,GO:0031333~negative regulation of protein complex assembly,GO:0033138~positive regulation of peptidyl-serine phosphorylation,GO:0034220~ion transmembrane transport,GO:0035019~somatic stem cell population maintenance,GO:0035023~regulation of Rho protein signal transduction,GO:0035556~intracellular signal transduction,GO:0035773~insulin secretion involved in cellular response to glucose stimulus,GO:0035994~response to muscle stretch,GO:0042060~wound healing,GO:0042981~regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043154~negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0045104~intermediate filament cytoskeleton organization,GO:0045595~regulation of cell differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0048538~thymus development,GO:0060324~face development,GO:0071550~death-inducing signaling complex assembly,GO:1902042~negative regulation of extrinsic apoptotic signaling pathway via death domain receptors,GO:2000145~regulation of cell motility,"]
[39.00000000000001,"PICK1","protein interacting with PRKCA 1(PICK1)","Homo sapiens",18,17,17.5,35,"GO:0002092~positive regulation of receptor internalization,GO:0006468~protein phosphorylation,GO:0006890~retrograde vesicle-mediated transport, Golgi to ER,GO:0007205~protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0015844~monoamine transport,GO:0021782~glial cell development,GO:0034315~regulation of Arp2/3 complex-mediated actin nucleation,GO:0034316~negative regulation of Arp2/3 complex-mediated actin nucleation,GO:0036294~cellular response to decreased oxygen levels,GO:0042149~cellular response to glucose starvation,GO:0043045~DNA methylation involved in embryo development,GO:0043046~DNA methylation involved in gamete generation,GO:0043113~receptor clustering,GO:0045161~neuronal ion channel clustering,GO:0060292~long term synaptic depression,GO:0097061~dendritic spine organization,GO:0097062~dendritic spine maintenance,","GO:0002092~positive regulation of receptor internalization,GO:0006468~protein phosphorylation,GO:0006890~retrograde vesicle-mediated transport, Golgi to ER,GO:0007205~protein kinase C-activating G-protein coupled receptor signaling pathway,GO:0015844~monoamine transport,GO:0021782~glial cell development,GO:0034315~regulation of Arp2/3 complex-mediated actin nucleation,GO:0034316~negative regulation of Arp2/3 complex-mediated actin nucleation,GO:0036294~cellular response to decreased oxygen levels,GO:0042149~cellular response to glucose starvation,GO:0043045~DNA methylation involved in embryo development,GO:0043046~DNA methylation involved in gamete generation,GO:0043113~receptor clustering,GO:0045161~neuronal ion channel clustering,GO:0060292~long term synaptic depression,GO:0097061~dendritic spine organization,GO:0097062~dendritic spine maintenance,"]
[40.00000000000001,"CHRFAM7A","CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion(CHRFAM7A)","Homo sapiens",34,0,17,34,"GO:0000187~activation of MAPK activity,GO:0001666~response to hypoxia,GO:0001988~positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure,GO:0006811~ion transport,GO:0006816~calcium ion transport,GO:0006874~cellular calcium ion homeostasis,GO:0006897~endocytosis,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007613~memory,GO:0008284~positive regulation of cell proliferation,GO:0008306~associative learning,GO:0014061~regulation of norepinephrine secretion,GO:0030317~sperm motility,GO:0032094~response to food,GO:0032225~regulation of synaptic transmission, dopaminergic,GO:0032691~negative regulation of interleukin-1 beta production,GO:0032715~negative regulation of interleukin-6 production,GO:0032720~negative regulation of tumor necrosis factor production,GO:0034220~ion transmembrane transport,GO:0034766~negative regulation of ion transmembrane transport,GO:0035094~response to nicotine,GO:0035095~behavioral response to nicotine,GO:0042110~T cell activation,GO:0042113~B cell activation,GO:0042391~regulation of membrane potential,GO:0045766~positive regulation of angiogenesis,GO:0048149~behavioral response to ethanol,GO:0050728~negative regulation of inflammatory response,GO:0050890~cognition,GO:0060112~generation of ovulation cycle rhythm,GO:1903049~negative regulation of acetylcholine-gated cation channel activity,"]
[40.00000000000001,"S100B","S100 calcium binding protein B(S100B)","Homo sapiens",17,17,17,34,"GO:0007409~axonogenesis,GO:0007417~central nervous system development,GO:0007611~learning or memory,GO:0007613~memory,GO:0008283~cell proliferation,GO:0008284~positive regulation of cell proliferation,GO:0008360~regulation of cell shape,GO:0043065~positive regulation of apoptotic process,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045087~innate immune response,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048708~astrocyte differentiation,GO:0051384~response to glucocorticoid,GO:0051597~response to methylmercury,GO:0060291~long-term synaptic potentiation,GO:0071456~cellular response to hypoxia,GO:2001015~negative regulation of skeletal muscle cell differentiation,","GO:0007409~axonogenesis,GO:0007417~central nervous system development,GO:0007611~learning or memory,GO:0007613~memory,GO:0008283~cell proliferation,GO:0008284~positive regulation of cell proliferation,GO:0008360~regulation of cell shape,GO:0043065~positive regulation of apoptotic process,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045087~innate immune response,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048708~astrocyte differentiation,GO:0051384~response to glucocorticoid,GO:0051597~response to methylmercury,GO:0060291~long-term synaptic potentiation,GO:0071456~cellular response to hypoxia,GO:2001015~negative regulation of skeletal muscle cell differentiation,"]
[40.00000000000001,"CNTNAP2","contactin associated protein-like 2(CNTNAP2)","Homo sapiens",17,17,17,34,"GO:0007155~cell adhesion,GO:0007420~brain development,GO:0007612~learning,GO:0008038~neuron recognition,GO:0019226~transmission of nerve impulse,GO:0021756~striatum development,GO:0021761~limbic system development,GO:0021794~thalamus development,GO:0021987~cerebral cortex development,GO:0030534~adult behavior,GO:0031175~neuron projection development,GO:0035176~social behavior,GO:0042297~vocal learning,GO:0045163~clustering of voltage-gated potassium channels,GO:0071109~superior temporal gyrus development,GO:0071205~protein localization to juxtaparanode region of axon,GO:0071625~vocalization behavior,","GO:0007155~cell adhesion,GO:0007420~brain development,GO:0007612~learning,GO:0008038~neuron recognition,GO:0019226~transmission of nerve impulse,GO:0021756~striatum development,GO:0021761~limbic system development,GO:0021794~thalamus development,GO:0021987~cerebral cortex development,GO:0030534~adult behavior,GO:0031175~neuron projection development,GO:0035176~social behavior,GO:0042297~vocal learning,GO:0045163~clustering of voltage-gated potassium channels,GO:0071109~superior temporal gyrus development,GO:0071205~protein localization to juxtaparanode region of axon,GO:0071625~vocalization behavior,"]
[40.00000000000001,"DISC1","disrupted in schizophrenia 1(DISC1)","Homo sapiens",17,17,17,34,"GO:0000226~microtubule cytoskeleton organization,GO:0001764~neuron migration,GO:0001954~positive regulation of cell-matrix adhesion,GO:0002052~positive regulation of neuroblast proliferation,GO:0021846~cell proliferation in forebrain,GO:0021852~pyramidal neuron migration,GO:0030177~positive regulation of Wnt signaling pathway,GO:0031929~TOR signaling,GO:0035058~nonmotile primary cilium assembly,GO:0045773~positive regulation of axon extension,GO:0051560~mitochondrial calcium ion homeostasis,GO:0051602~response to electrical stimulus,GO:0060070~canonical Wnt signaling pathway,GO:0060998~regulation of dendritic spine development,GO:0071539~protein localization to centrosome,GO:0090128~regulation of synapse maturation,GO:2000060~positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process,","GO:0000226~microtubule cytoskeleton organization,GO:0001764~neuron migration,GO:0001954~positive regulation of cell-matrix adhesion,GO:0002052~positive regulation of neuroblast proliferation,GO:0021846~cell proliferation in forebrain,GO:0021852~pyramidal neuron migration,GO:0030177~positive regulation of Wnt signaling pathway,GO:0031929~TOR signaling,GO:0035058~nonmotile primary cilium assembly,GO:0045773~positive regulation of axon extension,GO:0051560~mitochondrial calcium ion homeostasis,GO:0051602~response to electrical stimulus,GO:0060070~canonical Wnt signaling pathway,GO:0060998~regulation of dendritic spine development,GO:0071539~protein localization to centrosome,GO:0090128~regulation of synapse maturation,GO:2000060~positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process,"]
[41.00000000000001,"RUNX2","runt related transcription factor 2(RUNX2)","Homo sapiens",33,0,16.5,33,"GO:0001503~ossification,GO:0001649~osteoblast differentiation,GO:0001958~endochondral ossification,GO:0002051~osteoblast fate commitment,GO:0002062~chondrocyte differentiation,GO:0002063~chondrocyte development,GO:0002076~osteoblast development,GO:0006355~regulation of transcription, DNA-templated,GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006366~transcription from RNA polymerase II promoter,GO:0008284~positive regulation of cell proliferation,GO:0030097~hemopoiesis,GO:0030182~neuron differentiation,GO:0030217~T cell differentiation,GO:0030509~BMP signaling pathway,GO:0032332~positive regulation of chondrocyte differentiation,GO:0035115~embryonic forelimb morphogenesis,GO:0040036~regulation of fibroblast growth factor receptor signaling pathway,GO:0042475~odontogenesis of dentin-containing tooth,GO:0042487~regulation of odontogenesis of dentin-containing tooth,GO:0045595~regulation of cell differentiation,GO:0045669~positive regulation of osteoblast differentiation,GO:0045879~negative regulation of smoothened signaling pathway,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045893~positive regulation of transcription, DNA-templated,GO:0048469~cell maturation,GO:0048701~embryonic cranial skeleton morphogenesis,GO:0048863~stem cell differentiation,GO:0071773~cellular response to BMP stimulus,GO:1901522~positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus,"]
[42.000000000000014,"NLRP3","NLR family pyrin domain containing 3(NLRP3)","Homo sapiens",32,0,16,32,"GO:0002674~negative regulation of acute inflammatory response,GO:0002830~positive regulation of type 2 immune response,GO:0006351~transcription, DNA-templated,GO:0006915~apoptotic process,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0006952~defense response,GO:0006954~inflammatory response,GO:0007165~signal transduction,GO:0009595~detection of biotic stimulus,GO:0032088~negative regulation of NF-kappaB transcription factor activity,GO:0032611~interleukin-1 beta production,GO:0032621~interleukin-18 production,GO:0032736~positive regulation of interleukin-13 production,GO:0032753~positive regulation of interleukin-4 production,GO:0032754~positive regulation of interleukin-5 production,GO:0042347~negative regulation of NF-kappaB import into nucleus,GO:0043280~positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0044546~NLRP3 inflammasome complex assembly,GO:0045087~innate immune response,GO:0045630~positive regulation of T-helper 2 cell differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0050701~interleukin-1 secretion,GO:0050713~negative regulation of interleukin-1 beta secretion,GO:0050718~positive regulation of interleukin-1 beta secretion,GO:0050728~negative regulation of inflammatory response,GO:0051092~positive regulation of NF-kappaB transcription factor activity,GO:0051259~protein oligomerization,GO:0051607~defense response to virus,GO:0071222~cellular response to lipopolysaccharide,GO:2000321~positive regulation of T-helper 17 cell differentiation,GO:2000553~positive regulation of T-helper 2 cell cytokine production,"]
[42.000000000000014,"MMP14","matrix metallopeptidase 14(MMP14)","Homo sapiens",32,0,16,32,"GO:0001525~angiogenesis,GO:0001541~ovarian follicle development,GO:0001666~response to hypoxia,GO:0001935~endothelial cell proliferation,GO:0001958~endochondral ossification,GO:0006508~proteolysis,GO:0006979~response to oxidative stress,GO:0008584~male gonad development,GO:0009612~response to mechanical stimulus,GO:0009725~response to hormone,GO:0010831~positive regulation of myotube differentiation,GO:0010952~positive regulation of peptidase activity,GO:0014070~response to organic cyclic compound,GO:0016485~protein processing,GO:0022617~extracellular matrix disassembly,GO:0030307~positive regulation of cell growth,GO:0030324~lung development,GO:0030335~positive regulation of cell migration,GO:0030574~collagen catabolic process,GO:0031638~zymogen activation,GO:0035987~endodermal cell differentiation,GO:0035988~chondrocyte proliferation,GO:0043615~astrocyte cell migration,GO:0043627~response to estrogen,GO:0045579~positive regulation of B cell differentiation,GO:0045746~negative regulation of Notch signaling pathway,GO:0048701~embryonic cranial skeleton morphogenesis,GO:0048754~branching morphogenesis of an epithelial tube,GO:0048771~tissue remodeling,GO:0048870~cell motility,GO:0051895~negative regulation of focal adhesion assembly,GO:0097094~craniofacial suture morphogenesis,"]
[42.000000000000014,"ROBO1","roundabout guidance receptor 1(ROBO1)","Homo sapiens",16,16,16,32,"GO:0002042~cell migration involved in sprouting angiogenesis,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007399~nervous system development,GO:0007411~axon guidance,GO:0007507~heart development,GO:0016199~axon midline choice point recognition,GO:0021836~chemorepulsion involved in postnatal olfactory bulb interneuron migration,GO:0030336~negative regulation of cell migration,GO:0033600~negative regulation of mammary gland epithelial cell proliferation,GO:0035025~positive regulation of Rho protein signal transduction,GO:0035385~Roundabout signaling pathway,GO:0050772~positive regulation of axonogenesis,GO:0050925~negative regulation of negative chemotaxis,GO:0070100~negative regulation of chemokine-mediated signaling pathway,","GO:0002042~cell migration involved in sprouting angiogenesis,GO:0006919~activation of cysteine-type endopeptidase activity involved in apoptotic process,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007399~nervous system development,GO:0007411~axon guidance,GO:0007507~heart development,GO:0016199~axon midline choice point recognition,GO:0021836~chemorepulsion involved in postnatal olfactory bulb interneuron migration,GO:0030336~negative regulation of cell migration,GO:0033600~negative regulation of mammary gland epithelial cell proliferation,GO:0035025~positive regulation of Rho protein signal transduction,GO:0035385~Roundabout signaling pathway,GO:0050772~positive regulation of axonogenesis,GO:0050925~negative regulation of negative chemotaxis,GO:0070100~negative regulation of chemokine-mediated signaling pathway,"]
[43.000000000000014,"FGFR3","fibroblast growth factor receptor 3(FGFR3)","Homo sapiens",28,0,14,28,"GO:0000165~MAPK cascade,GO:0001501~skeletal system development,GO:0001958~endochondral ossification,GO:0002062~chondrocyte differentiation,GO:0003416~endochondral bone growth,GO:0007259~JAK-STAT cascade,GO:0007267~cell-cell signaling,GO:0008284~positive regulation of cell proliferation,GO:0008543~fibroblast growth factor receptor signaling pathway,GO:0010518~positive regulation of phospholipase activity,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0030282~bone mineralization,GO:0035988~chondrocyte proliferation,GO:0036092~phosphatidylinositol-3-phosphate biosynthetic process,GO:0042511~positive regulation of tyrosine phosphorylation of Stat1 protein,GO:0042517~positive regulation of tyrosine phosphorylation of Stat3 protein,GO:0043410~positive regulation of MAPK cascade,GO:0043547~positive regulation of GTPase activity,GO:0043552~positive regulation of phosphatidylinositol 3-kinase activity,GO:0046777~protein autophosphorylation,GO:0046854~phosphatidylinositol phosphorylation,GO:0048015~phosphatidylinositol-mediated signaling,GO:0048640~negative regulation of developmental growth,GO:0060349~bone morphogenesis,GO:0070374~positive regulation of ERK1 and ERK2 cascade,GO:0070977~bone maturation,GO:1902178~fibroblast growth factor receptor apoptotic signaling pathway,"]
[43.000000000000014,"GPC3","glypican 3(GPC3)","Homo sapiens",28,0,14,28,"GO:0001523~retinoid metabolic process,GO:0001658~branching involved in ureteric bud morphogenesis,GO:0006024~glycosaminoglycan biosynthetic process,GO:0006027~glycosaminoglycan catabolic process,GO:0009653~anatomical structure morphogenesis,GO:0009948~anterior/posterior axis specification,GO:0010171~body morphogenesis,GO:0010466~negative regulation of peptidase activity,GO:0030203~glycosaminoglycan metabolic process,GO:0030282~bone mineralization,GO:0030316~osteoclast differentiation,GO:0030324~lung development,GO:0030513~positive regulation of BMP signaling pathway,GO:0035116~embryonic hindlimb morphogenesis,GO:0045732~positive regulation of protein catabolic process,GO:0045807~positive regulation of endocytosis,GO:0045879~negative regulation of smoothened signaling pathway,GO:0045880~positive regulation of smoothened signaling pathway,GO:0045926~negative regulation of growth,GO:0046326~positive regulation of glucose import,GO:0050680~negative regulation of epithelial cell proliferation,GO:0060976~coronary vasculature development,GO:0072138~mesenchymal cell proliferation involved in ureteric bud development,GO:0072180~mesonephric duct morphogenesis,GO:0072203~cell proliferation involved in metanephros development,GO:0090090~negative regulation of canonical Wnt signaling pathway,GO:2000096~positive regulation of Wnt signaling pathway, planar cell polarity pathway,"]
[43.000000000000014,"IL1A","interleukin 1 alpha(IL1A)","Homo sapiens",28,0,14,28,"GO:0001660~fever generation,GO:0002248~connective tissue replacement involved in inflammatory response wound healing,GO:0006915~apoptotic process,GO:0006954~inflammatory response,GO:0006955~immune response,GO:0008283~cell proliferation,GO:0008285~negative regulation of cell proliferation,GO:0010575~positive regulation of vascular endothelial growth factor production,GO:0010628~positive regulation of gene expression,GO:0019221~cytokine-mediated signaling pathway,GO:0032755~positive regulation of interleukin-6 production,GO:0034605~cellular response to heat,GO:0035234~ectopic germ cell programmed cell death,GO:0043123~positive regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045086~positive regulation of interleukin-2 biosynthetic process,GO:0045766~positive regulation of angiogenesis,GO:0045840~positive regulation of mitotic nuclear division,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046330~positive regulation of JNK cascade,GO:0046688~response to copper ion,GO:0050714~positive regulation of protein secretion,GO:0050715~positive regulation of cytokine secretion,GO:0051781~positive regulation of cell division,GO:0070498~interleukin-1-mediated signaling pathway,GO:0071639~positive regulation of monocyte chemotactic protein-1 production,GO:0097192~extrinsic apoptotic signaling pathway in absence of ligand,GO:2000391~positive regulation of neutrophil extravasation,GO:2001240~negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,"]
[43.000000000000014,"HTR1A","5-hydroxytryptamine receptor 1A(HTR1A)","Homo sapiens",14,14,14,28,"GO:0001662~behavioral fear response,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007198~adenylate cyclase-inhibiting serotonin receptor signaling pathway,GO:0007210~serotonin receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0008283~cell proliferation,GO:0008284~positive regulation of cell proliferation,GO:0014062~regulation of serotonin secretion,GO:0035640~exploration behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042310~vasoconstriction,GO:0042428~serotonin metabolic process,GO:0046883~regulation of hormone secretion,GO:0050795~regulation of behavior,","GO:0001662~behavioral fear response,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007198~adenylate cyclase-inhibiting serotonin receptor signaling pathway,GO:0007210~serotonin receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0008283~cell proliferation,GO:0008284~positive regulation of cell proliferation,GO:0014062~regulation of serotonin secretion,GO:0035640~exploration behavior,GO:0042053~regulation of dopamine metabolic process,GO:0042310~vasoconstriction,GO:0042428~serotonin metabolic process,GO:0046883~regulation of hormone secretion,GO:0050795~regulation of behavior,"]
[43.000000000000014,"TNIP1","TNFAIP3 interacting protein 1(TNIP1)","Homo sapiens",14,14,14,28,"GO:0002755~MyD88-dependent toll-like receptor signaling pathway,GO:0006412~translation,GO:0006508~proteolysis,GO:0006952~defense response,GO:0006954~inflammatory response,GO:0007159~leukocyte cell-cell adhesion,GO:0009101~glycoprotein biosynthetic process,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045071~negative regulation of viral genome replication,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0050727~regulation of inflammatory response,GO:0050729~positive regulation of inflammatory response,GO:0070373~negative regulation of ERK1 and ERK2 cascade,GO:0085032~modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade,","GO:0002755~MyD88-dependent toll-like receptor signaling pathway,GO:0006412~translation,GO:0006508~proteolysis,GO:0006952~defense response,GO:0006954~inflammatory response,GO:0007159~leukocyte cell-cell adhesion,GO:0009101~glycoprotein biosynthetic process,GO:0043124~negative regulation of I-kappaB kinase/NF-kappaB signaling,GO:0045071~negative regulation of viral genome replication,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0050727~regulation of inflammatory response,GO:0050729~positive regulation of inflammatory response,GO:0070373~negative regulation of ERK1 and ERK2 cascade,GO:0085032~modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade,"]
[43.000000000000014,"DDC","dopa decarboxylase(DDC)","Homo sapiens",14,14,14,28,"GO:0006520~cellular amino acid metabolic process,GO:0007623~circadian rhythm,GO:0010259~multicellular organism aging,GO:0015842~aminergic neurotransmitter loading into synaptic vesicle,GO:0033076~isoquinoline alkaloid metabolic process,GO:0035690~cellular response to drug,GO:0042416~dopamine biosynthetic process,GO:0042423~catecholamine biosynthetic process,GO:0042427~serotonin biosynthetic process,GO:0046219~indolalkylamine biosynthetic process,GO:0046684~response to pyrethroid,GO:0052314~phytoalexin metabolic process,GO:0071312~cellular response to alkaloid,GO:0071363~cellular response to growth factor stimulus,","GO:0006520~cellular amino acid metabolic process,GO:0007623~circadian rhythm,GO:0010259~multicellular organism aging,GO:0015842~aminergic neurotransmitter loading into synaptic vesicle,GO:0033076~isoquinoline alkaloid metabolic process,GO:0035690~cellular response to drug,GO:0042416~dopamine biosynthetic process,GO:0042423~catecholamine biosynthetic process,GO:0042427~serotonin biosynthetic process,GO:0046219~indolalkylamine biosynthetic process,GO:0046684~response to pyrethroid,GO:0052314~phytoalexin metabolic process,GO:0071312~cellular response to alkaloid,GO:0071363~cellular response to growth factor stimulus,"]
[43.000000000000014,"MAOB","monoamine oxidase B(MAOB)","Homo sapiens",14,14,14,28,"GO:0009636~response to toxic substance,GO:0010044~response to aluminum ion,GO:0010269~response to selenium ion,GO:0014063~negative regulation of serotonin secretion,GO:0021762~substantia nigra development,GO:0032496~response to lipopolysaccharide,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0045964~positive regulation of dopamine metabolic process,GO:0050665~hydrogen peroxide biosynthetic process,GO:0051412~response to corticosterone,GO:0055114~oxidation-reduction process,","GO:0009636~response to toxic substance,GO:0010044~response to aluminum ion,GO:0010269~response to selenium ion,GO:0014063~negative regulation of serotonin secretion,GO:0021762~substantia nigra development,GO:0032496~response to lipopolysaccharide,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0042493~response to drug,GO:0045471~response to ethanol,GO:0045964~positive regulation of dopamine metabolic process,GO:0050665~hydrogen peroxide biosynthetic process,GO:0051412~response to corticosterone,GO:0055114~oxidation-reduction process,"]
[43.000000000000014,"PSEN2","presenilin 2(PSEN2)","Homo sapiens",14,14,14,28,"GO:0001666~response to hypoxia,GO:0006509~membrane protein ectodomain proteolysis,GO:0006816~calcium ion transport,GO:0007219~Notch signaling pathway,GO:0007220~Notch receptor processing,GO:0016485~protein processing,GO:0031293~membrane protein intracellular domain proteolysis,GO:0035556~intracellular signal transduction,GO:0042987~amyloid precursor protein catabolic process,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043085~positive regulation of catalytic activity,GO:0048013~ephrin receptor signaling pathway,GO:0050435~beta-amyloid metabolic process,","GO:0001666~response to hypoxia,GO:0006509~membrane protein ectodomain proteolysis,GO:0006816~calcium ion transport,GO:0007219~Notch signaling pathway,GO:0007220~Notch receptor processing,GO:0016485~protein processing,GO:0031293~membrane protein intracellular domain proteolysis,GO:0035556~intracellular signal transduction,GO:0042987~amyloid precursor protein catabolic process,GO:0043065~positive regulation of apoptotic process,GO:0043066~negative regulation of apoptotic process,GO:0043085~positive regulation of catalytic activity,GO:0048013~ephrin receptor signaling pathway,GO:0050435~beta-amyloid metabolic process,"]
[44.000000000000014,"ABCB1","ATP binding cassette subfamily B member 1(ABCB1)","Homo sapiens",15,12,13.5,27,"GO:0000086~G2/M transition of mitotic cell cycle,GO:0002481~antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent,GO:0002485~antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent,GO:0002489~antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent,GO:0002591~positive regulation of antigen processing and presentation of peptide antigen via MHC class I,GO:0006810~transport,GO:0006855~drug transmembrane transport,GO:0042493~response to drug,GO:0042908~xenobiotic transport,GO:0045332~phospholipid translocation,GO:0055085~transmembrane transport,GO:0072089~stem cell proliferation,","GO:0000086~G2/M transition of mitotic cell cycle,GO:0002481~antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent,GO:0002485~antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent,GO:0002489~antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent,GO:0002591~positive regulation of antigen processing and presentation of peptide antigen via MHC class I,GO:0006810~transport,GO:0006855~drug transmembrane transport,GO:0042493~response to drug,GO:0042908~xenobiotic transport,GO:0045332~phospholipid translocation,GO:0055085~transmembrane transport,GO:0072089~stem cell proliferation,"]
[45.000000000000014,"BDNF","brain derived neurotrophic factor(BDNF)","Homo sapiens",13,13,13,26,"GO:0007267~cell-cell signaling,GO:0007399~nervous system development,GO:0007411~axon guidance,GO:0007416~synapse assembly,GO:0010832~negative regulation of myotube differentiation,GO:0031547~brain-derived neurotrophic factor receptor signaling pathway,GO:0031550~positive regulation of brain-derived neurotrophic factor receptor signaling pathway,GO:0043524~negative regulation of neuron apoptotic process,GO:0048668~collateral sprouting,GO:0048672~positive regulation of collateral sprouting,GO:0051965~positive regulation of synapse assembly,GO:1900122~positive regulation of receptor binding,GO:2000008~regulation of protein localization to cell surface,","GO:0007267~cell-cell signaling,GO:0007399~nervous system development,GO:0007411~axon guidance,GO:0007416~synapse assembly,GO:0010832~negative regulation of myotube differentiation,GO:0031547~brain-derived neurotrophic factor receptor signaling pathway,GO:0031550~positive regulation of brain-derived neurotrophic factor receptor signaling pathway,GO:0043524~negative regulation of neuron apoptotic process,GO:0048668~collateral sprouting,GO:0048672~positive regulation of collateral sprouting,GO:0051965~positive regulation of synapse assembly,GO:1900122~positive regulation of receptor binding,GO:2000008~regulation of protein localization to cell surface,"]
[45.000000000000014,"MAPT","microtubule associated protein tau(MAPT)","Homo sapiens",13,13,13,26,"GO:0000226~microtubule cytoskeleton organization,GO:0001764~neuron migration,GO:0007628~adult walking behavior,GO:0008088~axo-dendritic transport,GO:0010506~regulation of autophagy,GO:0031113~regulation of microtubule polymerization,GO:0031116~positive regulation of microtubule polymerization,GO:0032387~negative regulation of intracellular transport,GO:0045773~positive regulation of axon extension,GO:0047497~mitochondrion transport along microtubule,GO:0048675~axon extension,GO:0048699~generation of neurons,GO:0060632~regulation of microtubule-based movement,","GO:0000226~microtubule cytoskeleton organization,GO:0001764~neuron migration,GO:0007628~adult walking behavior,GO:0008088~axo-dendritic transport,GO:0010506~regulation of autophagy,GO:0031113~regulation of microtubule polymerization,GO:0031116~positive regulation of microtubule polymerization,GO:0032387~negative regulation of intracellular transport,GO:0045773~positive regulation of axon extension,GO:0047497~mitochondrion transport along microtubule,GO:0048675~axon extension,GO:0048699~generation of neurons,GO:0060632~regulation of microtubule-based movement,"]
[46.00000000000002,"ARF1","ADP ribosylation factor 1(ARF1)","Homo sapiens",25,0,12.5,25,"GO:0002090~regulation of receptor internalization,GO:0006661~phosphatidylinositol biosynthetic process,GO:0006878~cellular copper ion homeostasis,GO:0006892~post-Golgi vesicle-mediated transport,GO:0007015~actin filament organization,GO:0007264~small GTPase mediated signal transduction,GO:0015031~protein transport,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0034315~regulation of Arp2/3 complex-mediated actin nucleation,GO:0034379~very-low-density lipoprotein particle assembly,GO:0043085~positive regulation of catalytic activity,GO:0045807~positive regulation of endocytosis,GO:0045956~positive regulation of calcium ion-dependent exocytosis,GO:0050690~regulation of defense response to virus by virus,GO:0050714~positive regulation of protein secretion,GO:0055108~Golgi to transport vesicle transport,GO:0060292~long term synaptic depression,GO:0060999~positive regulation of dendritic spine development,GO:0070142~synaptic vesicle budding,GO:0097061~dendritic spine organization,GO:0097212~lysosomal membrane organization,GO:1902307~positive regulation of sodium ion transmembrane transport,GO:1902824~positive regulation of late endosome to lysosome transport,GO:1902953~positive regulation of ER to Golgi vesicle-mediated transport,GO:1903725~regulation of phospholipid metabolic process,"]
[46.00000000000002,"DYRK1A","dual specificity tyrosine phosphorylation regulated kinase 1A(DYRK1A)","Homo sapiens",14,11,12.5,25,"GO:0000381~regulation of alternative mRNA splicing, via spliceosome,GO:0006468~protein phosphorylation,GO:0007399~nervous system development,GO:0007623~circadian rhythm,GO:0018105~peptidyl-serine phosphorylation,GO:0018107~peptidyl-threonine phosphorylation,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0043518~negative regulation of DNA damage response, signal transduction by p53 class mediator,GO:0046777~protein autophosphorylation,GO:0048025~negative regulation of mRNA splicing, via spliceosome,GO:0090312~positive regulation of protein deacetylation,","GO:0000381~regulation of alternative mRNA splicing, via spliceosome,GO:0006468~protein phosphorylation,GO:0007399~nervous system development,GO:0007623~circadian rhythm,GO:0018105~peptidyl-serine phosphorylation,GO:0018107~peptidyl-threonine phosphorylation,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0043518~negative regulation of DNA damage response, signal transduction by p53 class mediator,GO:0046777~protein autophosphorylation,GO:0048025~negative regulation of mRNA splicing, via spliceosome,GO:0090312~positive regulation of protein deacetylation,"]
[46.00000000000002,"ESR2","estrogen receptor 2(ESR2)","Homo sapiens",14,11,12.5,25,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0007267~cell-cell signaling,GO:0030308~negative regulation of cell growth,GO:0030520~intracellular estrogen receptor signaling pathway,GO:0045893~positive regulation of transcription, DNA-templated,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:1900116~extracellular negative regulation of signal transduction,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0007267~cell-cell signaling,GO:0030308~negative regulation of cell growth,GO:0030520~intracellular estrogen receptor signaling pathway,GO:0045893~positive regulation of transcription, DNA-templated,GO:0051091~positive regulation of sequence-specific DNA binding transcription factor activity,GO:1900116~extracellular negative regulation of signal transduction,"]
[47.00000000000003,"GABRB3","gamma-aminobutyric acid type A receptor beta3 subunit(GABRB3)","Homo sapiens",12,12,12,24,"GO:0006810~transport,GO:0007165~signal transduction,GO:0007605~sensory perception of sound,GO:0034220~ion transmembrane transport,GO:0043524~negative regulation of neuron apoptotic process,GO:0060021~palate development,GO:0060080~inhibitory postsynaptic potential,GO:0060119~inner ear receptor cell development,GO:0060384~innervation,GO:0071420~cellular response to histamine,GO:0090102~cochlea development,GO:1902476~chloride transmembrane transport,","GO:0006810~transport,GO:0007165~signal transduction,GO:0007605~sensory perception of sound,GO:0034220~ion transmembrane transport,GO:0043524~negative regulation of neuron apoptotic process,GO:0060021~palate development,GO:0060080~inhibitory postsynaptic potential,GO:0060119~inner ear receptor cell development,GO:0060384~innervation,GO:0071420~cellular response to histamine,GO:0090102~cochlea development,GO:1902476~chloride transmembrane transport,"]
[47.00000000000003,"GFAP","glial fibrillary acidic protein(GFAP)","Homo sapiens",12,12,12,24,"GO:0009611~response to wounding,GO:0010625~positive regulation of Schwann cell proliferation,GO:0010977~negative regulation of neuron projection development,GO:0014002~astrocyte development,GO:0030198~extracellular matrix organization,GO:0031102~neuron projection regeneration,GO:0043254~regulation of protein complex assembly,GO:0045109~intermediate filament organization,GO:0051580~regulation of neurotransmitter uptake,GO:0060020~Bergmann glial cell differentiation,GO:0060291~long-term synaptic potentiation,GO:1904714~regulation of chaperone-mediated autophagy,","GO:0009611~response to wounding,GO:0010625~positive regulation of Schwann cell proliferation,GO:0010977~negative regulation of neuron projection development,GO:0014002~astrocyte development,GO:0030198~extracellular matrix organization,GO:0031102~neuron projection regeneration,GO:0043254~regulation of protein complex assembly,GO:0045109~intermediate filament organization,GO:0051580~regulation of neurotransmitter uptake,GO:0060020~Bergmann glial cell differentiation,GO:0060291~long-term synaptic potentiation,GO:1904714~regulation of chaperone-mediated autophagy,"]
[47.00000000000003,"IMMP2L","inner mitochondrial membrane peptidase subunit 2(IMMP2L)","Homo sapiens",12,12,12,24,"GO:0001541~ovarian follicle development,GO:0006465~signal peptide processing,GO:0006627~protein processing involved in protein targeting to mitochondrion,GO:0006801~superoxide metabolic process,GO:0006974~cellular response to DNA damage stimulus,GO:0007283~spermatogenesis,GO:0007420~brain development,GO:0008015~blood circulation,GO:0022904~respiratory electron transport chain,GO:0030728~ovulation,GO:0033108~mitochondrial respiratory chain complex assembly,GO:0061300~cerebellum vasculature development,","GO:0001541~ovarian follicle development,GO:0006465~signal peptide processing,GO:0006627~protein processing involved in protein targeting to mitochondrion,GO:0006801~superoxide metabolic process,GO:0006974~cellular response to DNA damage stimulus,GO:0007283~spermatogenesis,GO:0007420~brain development,GO:0008015~blood circulation,GO:0022904~respiratory electron transport chain,GO:0030728~ovulation,GO:0033108~mitochondrial respiratory chain complex assembly,GO:0061300~cerebellum vasculature development,"]
[48.00000000000003,"TSC2","tuberous sclerosis 2(TSC2)","Homo sapiens",23,0,11.5,23,"GO:0001843~neural tube closure,GO:0006469~negative regulation of protein kinase activity,GO:0006606~protein import into nucleus,GO:0006897~endocytosis,GO:0007050~cell cycle arrest,GO:0007507~heart development,GO:0008104~protein localization,GO:0008285~negative regulation of cell proliferation,GO:0014067~negative regulation of phosphatidylinositol 3-kinase signaling,GO:0016032~viral process,GO:0016192~vesicle-mediated transport,GO:0030100~regulation of endocytosis,GO:0030178~negative regulation of Wnt signaling pathway,GO:0032007~negative regulation of TOR signaling,GO:0043491~protein kinase B signaling,GO:0043547~positive regulation of GTPase activity,GO:0046626~regulation of insulin receptor signaling pathway,GO:0046627~negative regulation of insulin receptor signaling pathway,GO:0048009~insulin-like growth factor receptor signaling pathway,GO:0050918~positive chemotaxis,GO:0051056~regulation of small GTPase mediated signal transduction,GO:0051726~regulation of cell cycle,GO:0051898~negative regulation of protein kinase B signaling,"]
[49.00000000000003,"BCAR1","BCAR1, Cas family scaffolding protein(BCAR1)","Homo sapiens",22,0,11,22,"GO:0001558~regulation of cell growth,GO:0007015~actin filament organization,GO:0007155~cell adhesion,GO:0007173~epidermal growth factor receptor signaling pathway,GO:0007186~G-protein coupled receptor signaling pathway,GO:0007229~integrin-mediated signaling pathway,GO:0008283~cell proliferation,GO:0008286~insulin receptor signaling pathway,GO:0010595~positive regulation of endothelial cell migration,GO:0016477~cell migration,GO:0030335~positive regulation of cell migration,GO:0035729~cellular response to hepatocyte growth factor stimulus,GO:0042981~regulation of apoptotic process,GO:0048008~platelet-derived growth factor receptor signaling pathway,GO:0048010~vascular endothelial growth factor receptor signaling pathway,GO:0048011~neurotrophin TRK receptor signaling pathway,GO:0048012~hepatocyte growth factor receptor signaling pathway,GO:0050851~antigen receptor-mediated signaling pathway,GO:0050852~T cell receptor signaling pathway,GO:0050853~B cell receptor signaling pathway,GO:0051301~cell division,GO:0060326~cell chemotaxis,"]
[49.00000000000003,"SCN1A","sodium voltage-gated channel alpha subunit 1(SCN1A)","Homo sapiens",11,11,11,22,"GO:0006814~sodium ion transport,GO:0007628~adult walking behavior,GO:0019227~neuronal action potential propagation,GO:0019228~neuronal action potential,GO:0034765~regulation of ion transmembrane transport,GO:0035725~sodium ion transmembrane transport,GO:0050884~neuromuscular process controlling posture,GO:0050966~detection of mechanical stimulus involved in sensory perception of pain,GO:0060078~regulation of postsynaptic membrane potential,GO:0086002~cardiac muscle cell action potential involved in contraction,GO:0086010~membrane depolarization during action potential,","GO:0006814~sodium ion transport,GO:0007628~adult walking behavior,GO:0019227~neuronal action potential propagation,GO:0019228~neuronal action potential,GO:0034765~regulation of ion transmembrane transport,GO:0035725~sodium ion transmembrane transport,GO:0050884~neuromuscular process controlling posture,GO:0050966~detection of mechanical stimulus involved in sensory perception of pain,GO:0060078~regulation of postsynaptic membrane potential,GO:0086002~cardiac muscle cell action potential involved in contraction,GO:0086010~membrane depolarization during action potential,"]
[50.00000000000003,"BCL11B","B-cell CLL/lymphoma 11B(BCL11B)","Homo sapiens",21,0,10.5,21,"GO:0003334~keratinocyte development,GO:0003382~epithelial cell morphogenesis,GO:0006366~transcription from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0008285~negative regulation of cell proliferation,GO:0010837~regulation of keratinocyte proliferation,GO:0019216~regulation of lipid metabolic process,GO:0021773~striatal medium spiny neuron differentiation,GO:0021902~commitment of neuronal cell to specific neuron type in forebrain,GO:0022008~neurogenesis,GO:0031077~post-embryonic camera-type eye development,GO:0033077~T cell differentiation in thymus,GO:0033153~T cell receptor V(D)J recombination,GO:0042475~odontogenesis of dentin-containing tooth,GO:0043066~negative regulation of apoptotic process,GO:0043368~positive T cell selection,GO:0045664~regulation of neuron differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0046632~alpha-beta T cell differentiation,GO:0048538~thymus development,GO:0071678~olfactory bulb axon guidance,"]
[50.00000000000003,"HDAC9","histone deacetylase 9(HDAC9)","Homo sapiens",21,0,10.5,21,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0001975~response to amphetamine,GO:0006351~transcription, DNA-templated,GO:0006954~inflammatory response,GO:0007507~heart development,GO:0016575~histone deacetylation,GO:0030182~neuron differentiation,GO:0030183~B cell differentiation,GO:0032869~cellular response to insulin stimulus,GO:0034983~peptidyl-lysine deacetylation,GO:0040029~regulation of gene expression, epigenetic,GO:0042113~B cell activation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0048742~regulation of skeletal muscle fiber development,GO:0051153~regulation of striated muscle cell differentiation,GO:0070932~histone H3 deacetylation,GO:0070933~histone H4 deacetylation,GO:0090050~positive regulation of cell migration involved in sprouting angiogenesis,"]
[50.00000000000003,"LPL","lipoprotein lipase(LPL)","Homo sapiens",21,0,10.5,21,"GO:0001523~retinoid metabolic process,GO:0006629~lipid metabolic process,GO:0006633~fatty acid biosynthetic process,GO:0006641~triglyceride metabolic process,GO:0006644~phospholipid metabolic process,GO:0009409~response to cold,GO:0009749~response to glucose,GO:0010744~positive regulation of macrophage derived foam cell differentiation,GO:0010886~positive regulation of cholesterol storage,GO:0010890~positive regulation of sequestering of triglyceride,GO:0016042~lipid catabolic process,GO:0019432~triglyceride biosynthetic process,GO:0019433~triglyceride catabolic process,GO:0034371~chylomicron remodeling,GO:0034372~very-low-density lipoprotein particle remodeling,GO:0042157~lipoprotein metabolic process,GO:0042493~response to drug,GO:0042632~cholesterol homeostasis,GO:0050729~positive regulation of inflammatory response,GO:0070328~triglyceride homeostasis,GO:0090197~positive regulation of chemokine secretion,"]
[50.00000000000003,"PRNP","prion protein(PRNP)","Homo sapiens",21,0,10.5,21,"GO:0001933~negative regulation of protein phosphorylation,GO:0006878~cellular copper ion homeostasis,GO:0006979~response to oxidative stress,GO:0007050~cell cycle arrest,GO:0007611~learning or memory,GO:0008152~metabolic process,GO:0032689~negative regulation of interferon-gamma production,GO:0032700~negative regulation of interleukin-17 production,GO:0032703~negative regulation of interleukin-2 production,GO:0032880~regulation of protein localization,GO:0035690~cellular response to drug,GO:0043066~negative regulation of apoptotic process,GO:0043433~negative regulation of sequence-specific DNA binding transcription factor activity,GO:0046007~negative regulation of activated T cell proliferation,GO:0046686~response to cadmium ion,GO:0046688~response to copper ion,GO:0050860~negative regulation of T cell receptor signaling pathway,GO:0051260~protein homooligomerization,GO:0070885~negative regulation of calcineurin-NFAT signaling cascade,GO:0071280~cellular response to copper ion,GO:1901379~regulation of potassium ion transmembrane transport,"]
[51.00000000000004,"BCHE","butyrylcholinesterase(BCHE)","Homo sapiens",10,10,10,20,"GO:0007612~learning,GO:0008285~negative regulation of cell proliferation,GO:0014016~neuroblast differentiation,GO:0019695~choline metabolic process,GO:0042493~response to drug,GO:0043279~response to alkaloid,GO:0050783~cocaine metabolic process,GO:0050805~negative regulation of synaptic transmission,GO:0051384~response to glucocorticoid,GO:0051593~response to folic acid,","GO:0007612~learning,GO:0008285~negative regulation of cell proliferation,GO:0014016~neuroblast differentiation,GO:0019695~choline metabolic process,GO:0042493~response to drug,GO:0043279~response to alkaloid,GO:0050783~cocaine metabolic process,GO:0050805~negative regulation of synaptic transmission,GO:0051384~response to glucocorticoid,GO:0051593~response to folic acid,"]
[51.00000000000004,"GRIN2B","glutamate ionotropic receptor NMDA type subunit 2B(GRIN2B)","Homo sapiens",10,10,10,20,"GO:0000165~MAPK cascade,GO:0006810~transport,GO:0007215~glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007611~learning or memory,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0043547~positive regulation of GTPase activity,GO:0045471~response to ethanol,GO:0048013~ephrin receptor signaling pathway,","GO:0000165~MAPK cascade,GO:0006810~transport,GO:0007215~glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007611~learning or memory,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0043547~positive regulation of GTPase activity,GO:0045471~response to ethanol,GO:0048013~ephrin receptor signaling pathway,"]
[51.00000000000004,"HP","haptoglobin(HP)","Homo sapiens",10,10,10,20,"GO:0002376~immune system process,GO:0006898~receptor-mediated endocytosis,GO:0006952~defense response,GO:0006953~acute-phase response,GO:0010942~positive regulation of cell death,GO:0042542~response to hydrogen peroxide,GO:0042742~defense response to bacterium,GO:0051354~negative regulation of oxidoreductase activity,GO:0098869~cellular oxidant detoxification,GO:2000296~negative regulation of hydrogen peroxide catabolic process,","GO:0002376~immune system process,GO:0006898~receptor-mediated endocytosis,GO:0006952~defense response,GO:0006953~acute-phase response,GO:0010942~positive regulation of cell death,GO:0042542~response to hydrogen peroxide,GO:0042742~defense response to bacterium,GO:0051354~negative regulation of oxidoreductase activity,GO:0098869~cellular oxidant detoxification,GO:2000296~negative regulation of hydrogen peroxide catabolic process,"]
[51.00000000000004,"HLA-DQB1","major histocompatibility complex, class II, DQ beta 1(HLA-DQB1)","Homo sapiens",10,10,10,20,"GO:0002381~immunoglobulin production involved in immunoglobulin mediated immune response,GO:0002455~humoral immune response mediated by circulating immunoglobulin,GO:0002474~antigen processing and presentation of peptide antigen via MHC class I,GO:0002504~antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,GO:0006955~immune response,GO:0019882~antigen processing and presentation,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0031295~T cell costimulation,GO:0050852~T cell receptor signaling pathway,GO:0060333~interferon-gamma-mediated signaling pathway,","GO:0002381~immunoglobulin production involved in immunoglobulin mediated immune response,GO:0002455~humoral immune response mediated by circulating immunoglobulin,GO:0002474~antigen processing and presentation of peptide antigen via MHC class I,GO:0002504~antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,GO:0006955~immune response,GO:0019882~antigen processing and presentation,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0031295~T cell costimulation,GO:0050852~T cell receptor signaling pathway,GO:0060333~interferon-gamma-mediated signaling pathway,"]
[51.00000000000004,"MAP1B","microtubule associated protein 1B(MAP1B)","Homo sapiens",10,10,10,20,"GO:0000226~microtubule cytoskeleton organization,GO:0001578~microtubule bundle formation,GO:0007399~nervous system development,GO:0009987~cellular process,GO:0016358~dendrite development,GO:0032387~negative regulation of intracellular transport,GO:0045773~positive regulation of axon extension,GO:0047497~mitochondrion transport along microtubule,GO:0048675~axon extension,GO:0061162~establishment of monopolar cell polarity,","GO:0000226~microtubule cytoskeleton organization,GO:0001578~microtubule bundle formation,GO:0007399~nervous system development,GO:0009987~cellular process,GO:0016358~dendrite development,GO:0032387~negative regulation of intracellular transport,GO:0045773~positive regulation of axon extension,GO:0047497~mitochondrion transport along microtubule,GO:0048675~axon extension,GO:0061162~establishment of monopolar cell polarity,"]
[52.00000000000004,"STXBP1","syntaxin binding protein 1(STXBP1)","Homo sapiens",19,0,9.5,19,"GO:0002576~platelet degranulation,GO:0006904~vesicle docking involved in exocytosis,GO:0007269~neurotransmitter secretion,GO:0007274~neuromuscular synaptic transmission,GO:0007412~axon target recognition,GO:0010807~regulation of synaptic vesicle priming,GO:0014047~glutamate secretion,GO:0015031~protein transport,GO:0016188~synaptic vesicle maturation,GO:0031630~regulation of synaptic vesicle fusion to presynaptic membrane,GO:0032229~negative regulation of synaptic transmission, GABAergic,GO:0035542~regulation of SNARE complex assembly,GO:0043524~negative regulation of neuron apoptotic process,GO:0045956~positive regulation of calcium ion-dependent exocytosis,GO:0050821~protein stabilization,GO:0060292~long term synaptic depression,GO:0070527~platelet aggregation,GO:0072659~protein localization to plasma membrane,"]
[52.00000000000004,"CD83","CD83 molecule(CD83)","Homo sapiens",10,9,9.5,19,"GO:0001817~regulation of cytokine production,GO:0006952~defense response,GO:0006959~humoral immune response,GO:0007165~signal transduction,GO:0014070~response to organic cyclic compound,GO:0032713~negative regulation of interleukin-4 production,GO:0032733~positive regulation of interleukin-10 production,GO:0032743~positive regulation of interleukin-2 production,GO:0043372~positive regulation of CD4-positive, alpha-beta T cell differentiation,","GO:0001817~regulation of cytokine production,GO:0006952~defense response,GO:0006959~humoral immune response,GO:0007165~signal transduction,GO:0014070~response to organic cyclic compound,GO:0032713~negative regulation of interleukin-4 production,GO:0032733~positive regulation of interleukin-10 production,GO:0032743~positive regulation of interleukin-2 production,GO:0043372~positive regulation of CD4-positive, alpha-beta T cell differentiation,"]
[53.00000000000004,"ASPM","abnormal spindle microtubule assembly(ASPM)","Homo sapiens",18,0,9,18,"GO:0001764~neuron migration,GO:0002052~positive regulation of neuroblast proliferation,GO:0007051~spindle organization,GO:0007067~mitotic nuclear division,GO:0007283~spermatogenesis,GO:0008584~male gonad development,GO:0021873~forebrain neuroblast division,GO:0021987~cerebral cortex development,GO:0045665~negative regulation of neuron differentiation,GO:0045769~negative regulation of asymmetric cell division,GO:0048477~oogenesis,GO:0048589~developmental growth,GO:0051445~regulation of meiotic cell cycle,GO:0051653~spindle localization,GO:0051661~maintenance of centrosome location,GO:0090263~positive regulation of canonical Wnt signaling pathway,GO:0090306~spindle assembly involved in meiosis,GO:0097150~neuronal stem cell population maintenance,"]
[53.00000000000004,"CYFIP1","cytoplasmic FMR1 interacting protein 1(CYFIP1)","Homo sapiens",9,9,9,18,"GO:0008360~regulation of cell shape,GO:0016601~Rac protein signal transduction,GO:0030032~lamellipodium assembly,GO:0031529~ruffle organization,GO:0038096~Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0048010~vascular endothelial growth factor receptor signaling pathway,GO:0048675~axon extension,GO:0050890~cognition,GO:2000601~positive regulation of Arp2/3 complex-mediated actin nucleation,","GO:0008360~regulation of cell shape,GO:0016601~Rac protein signal transduction,GO:0030032~lamellipodium assembly,GO:0031529~ruffle organization,GO:0038096~Fc-gamma receptor signaling pathway involved in phagocytosis,GO:0048010~vascular endothelial growth factor receptor signaling pathway,GO:0048675~axon extension,GO:0050890~cognition,GO:2000601~positive regulation of Arp2/3 complex-mediated actin nucleation,"]
[54.00000000000004,"SPTBN1","spectrin beta, non-erythrocytic 1(SPTBN1)","Homo sapiens",17,0,8.5,17,"GO:0000165~MAPK cascade,GO:0000281~mitotic cytokinesis,GO:0006888~ER to Golgi vesicle-mediated transport,GO:0007009~plasma membrane organization,GO:0007010~cytoskeleton organization,GO:0007182~common-partner SMAD protein phosphorylation,GO:0007184~SMAD protein import into nucleus,GO:0007411~axon guidance,GO:0043001~Golgi to plasma membrane protein transport,GO:0043547~positive regulation of GTPase activity,GO:0051693~actin filament capping,GO:0071709~membrane assembly,GO:0072661~protein targeting to plasma membrane,GO:0098609~cell-cell adhesion,GO:1900042~positive regulation of interleukin-2 secretion,GO:1903076~regulation of protein localization to plasma membrane,GO:1903078~positive regulation of protein localization to plasma membrane,"]
[54.00000000000004,"GRIK1","glutamate ionotropic receptor kainate type subunit 1(GRIK1)","Homo sapiens",9,8,8.5,17,"GO:0006810~transport,GO:0007215~glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007399~nervous system development,GO:0007417~central nervous system development,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0051966~regulation of synaptic transmission, glutamatergic,","GO:0006810~transport,GO:0007215~glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007399~nervous system development,GO:0007417~central nervous system development,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0051966~regulation of synaptic transmission, glutamatergic,"]
[55.00000000000004,"SLC1A2","solute carrier family 1 member 2(SLC1A2)","Homo sapiens",16,0,8,16,"GO:0006811~ion transport,GO:0007268~chemical synaptic transmission,GO:0007632~visual behavior,GO:0009611~response to wounding,GO:0010259~multicellular organism aging,GO:0014047~glutamate secretion,GO:0021537~telencephalon development,GO:0030534~adult behavior,GO:0031668~cellular response to extracellular stimulus,GO:0035264~multicellular organism growth,GO:0042493~response to drug,GO:0043200~response to amino acid,GO:0046326~positive regulation of glucose import,GO:0051938~L-glutamate import,GO:0070779~D-aspartate import,GO:0089711~L-glutamate transmembrane transport,"]
[55.00000000000004,"NEUROD6","neuronal differentiation 6(NEUROD6)","Homo sapiens",9,7,8,16,"GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0007399~nervous system development,GO:0021542~dentate gyrus development,GO:0030154~cell differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,","GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0007399~nervous system development,GO:0021542~dentate gyrus development,GO:0030154~cell differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,"]
[55.00000000000004,"CDKL5","cyclin dependent kinase like 5(CDKL5)","Homo sapiens",8,8,8,16,"GO:0001764~neuron migration,GO:0006468~protein phosphorylation,GO:0043547~positive regulation of GTPase activity,GO:0045773~positive regulation of axon extension,GO:0046777~protein autophosphorylation,GO:0050773~regulation of dendrite development,GO:0050775~positive regulation of dendrite morphogenesis,GO:0051726~regulation of cell cycle,","GO:0001764~neuron migration,GO:0006468~protein phosphorylation,GO:0043547~positive regulation of GTPase activity,GO:0045773~positive regulation of axon extension,GO:0046777~protein autophosphorylation,GO:0050773~regulation of dendrite development,GO:0050775~positive regulation of dendrite morphogenesis,GO:0051726~regulation of cell cycle,"]
[55.00000000000004,"CYP19A1","cytochrome P450 family 19 subfamily A member 1(CYP19A1)","Homo sapiens",8,8,8,16,"GO:0002677~negative regulation of chronic inflammatory response,GO:0006694~steroid biosynthetic process,GO:0006703~estrogen biosynthetic process,GO:0008209~androgen metabolic process,GO:0010760~negative regulation of macrophage chemotaxis,GO:0016125~sterol metabolic process,GO:0055114~oxidation-reduction process,GO:0060736~prostate gland growth,","GO:0002677~negative regulation of chronic inflammatory response,GO:0006694~steroid biosynthetic process,GO:0006703~estrogen biosynthetic process,GO:0008209~androgen metabolic process,GO:0010760~negative regulation of macrophage chemotaxis,GO:0016125~sterol metabolic process,GO:0055114~oxidation-reduction process,GO:0060736~prostate gland growth,"]
[55.00000000000004,"DCDC2","doublecortin domain containing 2(DCDC2)","Homo sapiens",8,8,8,16,"GO:0001764~neuron migration,GO:0006968~cellular defense response,GO:0007605~sensory perception of sound,GO:0030030~cell projection organization,GO:0030111~regulation of Wnt signaling pathway,GO:0035556~intracellular signal transduction,GO:0045880~positive regulation of smoothened signaling pathway,GO:1902017~regulation of cilium assembly,","GO:0001764~neuron migration,GO:0006968~cellular defense response,GO:0007605~sensory perception of sound,GO:0030030~cell projection organization,GO:0030111~regulation of Wnt signaling pathway,GO:0035556~intracellular signal transduction,GO:0045880~positive regulation of smoothened signaling pathway,GO:1902017~regulation of cilium assembly,"]
[55.00000000000004,"PRL","prolactin(PRL)","Homo sapiens",8,8,8,16,"GO:0007166~cell surface receptor signaling pathway,GO:0007565~female pregnancy,GO:0007595~lactation,GO:0008283~cell proliferation,GO:0040014~regulation of multicellular organism growth,GO:0044267~cellular protein metabolic process,GO:0046427~positive regulation of JAK-STAT cascade,GO:0060397~JAK-STAT cascade involved in growth hormone signaling pathway,","GO:0007166~cell surface receptor signaling pathway,GO:0007565~female pregnancy,GO:0007595~lactation,GO:0008283~cell proliferation,GO:0040014~regulation of multicellular organism growth,GO:0044267~cellular protein metabolic process,GO:0046427~positive regulation of JAK-STAT cascade,GO:0060397~JAK-STAT cascade involved in growth hormone signaling pathway,"]
[55.00000000000004,"SYP","synaptophysin(SYP)","Homo sapiens",8,8,8,16,"GO:0006897~endocytosis,GO:0016188~synaptic vesicle maturation,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048172~regulation of short-term neuronal synaptic plasticity,GO:0048499~synaptic vesicle membrane organization,GO:0071310~cellular response to organic substance,GO:2000474~regulation of opioid receptor signaling pathway,","GO:0006897~endocytosis,GO:0016188~synaptic vesicle maturation,GO:0048168~regulation of neuronal synaptic plasticity,GO:0048169~regulation of long-term neuronal synaptic plasticity,GO:0048172~regulation of short-term neuronal synaptic plasticity,GO:0048499~synaptic vesicle membrane organization,GO:0071310~cellular response to organic substance,GO:2000474~regulation of opioid receptor signaling pathway,"]
[55.00000000000004,"TET3","tet methylcytosine dioxygenase 3(TET3)","Homo sapiens",8,8,8,16,"GO:0006211~5-methylcytosine catabolic process,GO:0006493~protein O-linked glycosylation,GO:0019511~peptidyl-proline hydroxylation,GO:0044727~DNA demethylation of male pronucleus,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0070989~oxidative demethylation,GO:0080111~DNA demethylation,GO:0080182~histone H3-K4 trimethylation,","GO:0006211~5-methylcytosine catabolic process,GO:0006493~protein O-linked glycosylation,GO:0019511~peptidyl-proline hydroxylation,GO:0044727~DNA demethylation of male pronucleus,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0070989~oxidative demethylation,GO:0080111~DNA demethylation,GO:0080182~histone H3-K4 trimethylation,"]
[56.00000000000005,"CACNA1H","calcium voltage-gated channel subunit alpha1 H(CACNA1H)","Homo sapiens",15,0,7.5,15,"GO:0006810~transport,GO:0006936~muscle contraction,GO:0007517~muscle organ development,GO:0007520~myoblast fusion,GO:0008016~regulation of heart contraction,GO:0032342~aldosterone biosynthetic process,GO:0032870~cellular response to hormone stimulus,GO:0034651~cortisol biosynthetic process,GO:0034765~regulation of ion transmembrane transport,GO:0035865~cellular response to potassium ion,GO:0042391~regulation of membrane potential,GO:0070509~calcium ion import,GO:0070588~calcium ion transmembrane transport,GO:0086010~membrane depolarization during action potential,GO:2000344~positive regulation of acrosome reaction,"]
[56.00000000000005,"GABRA5","gamma-aminobutyric acid type A receptor alpha5 subunit(GABRA5)","Homo sapiens",15,0,7.5,15,"GO:0001662~behavioral fear response,GO:0006810~transport,GO:0006821~chloride transport,GO:0007165~signal transduction,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007420~brain development,GO:0007605~sensory perception of sound,GO:0008306~associative learning,GO:0034220~ion transmembrane transport,GO:0043524~negative regulation of neuron apoptotic process,GO:0060119~inner ear receptor cell development,GO:0060384~innervation,GO:0090102~cochlea development,GO:1902476~chloride transmembrane transport,"]
[56.00000000000005,"CHRNA2","cholinergic receptor nicotinic alpha 2 subunit(CHRNA2)","Homo sapiens",8,7,7.5,15,"GO:0006811~ion transport,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0035094~response to nicotine,GO:0051291~protein heterooligomerization,GO:0098655~cation transmembrane transport,","GO:0006811~ion transport,GO:0007165~signal transduction,GO:0007271~synaptic transmission, cholinergic,GO:0007274~neuromuscular synaptic transmission,GO:0035094~response to nicotine,GO:0051291~protein heterooligomerization,GO:0098655~cation transmembrane transport,"]
[57.000000000000036,"ARX","aristaless related homeobox(ARX)","Homo sapiens",14,0,7,14,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0006351~transcription, DNA-templated,GO:0007411~axon guidance,GO:0010628~positive regulation of gene expression,GO:0021759~globus pallidus development,GO:0021800~cerebral cortex tangential migration,GO:0021831~embryonic olfactory bulb interneuron precursor migration,GO:0021846~cell proliferation in forebrain,GO:0021853~cerebral cortex GABAergic interneuron migration,GO:0042127~regulation of cell proliferation,GO:0044241~lipid digestion,GO:0046622~positive regulation of organ growth,GO:0072148~epithelial cell fate commitment,"]
[57.000000000000036,"GABRB2","gamma-aminobutyric acid type A receptor beta2 subunit(GABRB2)","Homo sapiens",14,0,7,14,"GO:0006810~transport,GO:0006811~ion transport,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0007268~chemical synaptic transmission,GO:0007605~sensory perception of sound,GO:0034220~ion transmembrane transport,GO:0043524~negative regulation of neuron apoptotic process,GO:0051932~synaptic transmission, GABAergic,GO:0060119~inner ear receptor cell development,GO:0060384~innervation,GO:0071420~cellular response to histamine,GO:0090102~cochlea development,GO:1902476~chloride transmembrane transport,"]
[57.000000000000036,"RYR1","ryanodine receptor 1(RYR1)","Homo sapiens",14,0,7,14,"GO:0001666~response to hypoxia,GO:0003151~outflow tract morphogenesis,GO:0006816~calcium ion transport,GO:0006936~muscle contraction,GO:0014808~release of sequestered calcium ion into cytosol by sarcoplasmic reticulum,GO:0031000~response to caffeine,GO:0034220~ion transmembrane transport,GO:0043588~skin development,GO:0043931~ossification involved in bone maturation,GO:0048741~skeletal muscle fiber development,GO:0051209~release of sequestered calcium ion into cytosol,GO:0051480~regulation of cytosolic calcium ion concentration,GO:0071313~cellular response to caffeine,GO:1903779~regulation of cardiac conduction,"]
[57.000000000000036,"ATP2C2","ATPase secretory pathway Ca2+ transporting 2(ATP2C2)","Homo sapiens",7,7,7,14,"GO:0006874~cellular calcium ion homeostasis,GO:0034220~ion transmembrane transport,GO:0061180~mammary gland epithelium development,GO:0070588~calcium ion transmembrane transport,GO:0071421~manganese ion transmembrane transport,GO:0072661~protein targeting to plasma membrane,GO:0090280~positive regulation of calcium ion import,","GO:0006874~cellular calcium ion homeostasis,GO:0034220~ion transmembrane transport,GO:0061180~mammary gland epithelium development,GO:0070588~calcium ion transmembrane transport,GO:0071421~manganese ion transmembrane transport,GO:0072661~protein targeting to plasma membrane,GO:0090280~positive regulation of calcium ion import,"]
[57.000000000000036,"SH2B1","SH2B adaptor protein 1(SH2B1)","Homo sapiens",7,7,7,14,"GO:0007165~signal transduction,GO:0007596~blood coagulation,GO:0009967~positive regulation of signal transduction,GO:0030032~lamellipodium assembly,GO:0035556~intracellular signal transduction,GO:0045840~positive regulation of mitotic nuclear division,GO:2000278~regulation of DNA biosynthetic process,","GO:0007165~signal transduction,GO:0007596~blood coagulation,GO:0009967~positive regulation of signal transduction,GO:0030032~lamellipodium assembly,GO:0035556~intracellular signal transduction,GO:0045840~positive regulation of mitotic nuclear division,GO:2000278~regulation of DNA biosynthetic process,"]
[57.000000000000036,"GTF2I","general transcription factor IIi(GTF2I)","Homo sapiens",7,7,7,14,"GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006366~transcription from RNA polymerase II promoter,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0014886~transition between slow and fast fiber,GO:0016525~negative regulation of angiogenesis,GO:0051481~negative regulation of cytosolic calcium ion concentration,","GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006366~transcription from RNA polymerase II promoter,GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0014886~transition between slow and fast fiber,GO:0016525~negative regulation of angiogenesis,GO:0051481~negative regulation of cytosolic calcium ion concentration,"]
[58.000000000000036,"LMO4","LIM domain only 4(LMO4)","Homo sapiens",13,0,6.5,13,"GO:0001843~neural tube closure,GO:0003281~ventricular septum development,GO:0006366~transcription from RNA polymerase II promoter,GO:0021514~ventral spinal cord interneuron differentiation,GO:0021522~spinal cord motor neuron differentiation,GO:0021527~spinal cord association neuron differentiation,GO:0030334~regulation of cell migration,GO:0031333~negative regulation of protein complex assembly,GO:0033674~positive regulation of kinase activity,GO:0042659~regulation of cell fate specification,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048538~thymus development,GO:0050865~regulation of cell activation,"]
[58.000000000000036,"ALB","albumin(ALB)","Homo sapiens",13,0,6.5,13,"GO:0001895~retina homeostasis,GO:0002576~platelet degranulation,GO:0006810~transport,GO:0006898~receptor-mediated endocytosis,GO:0009267~cellular response to starvation,GO:0015721~bile acid and bile salt transport,GO:0019836~hemolysis by symbiont of host erythrocytes,GO:0042157~lipoprotein metabolic process,GO:0043066~negative regulation of apoptotic process,GO:0043069~negative regulation of programmed cell death,GO:0043252~sodium-independent organic anion transport,GO:0051659~maintenance of mitochondrion location,GO:0098869~cellular oxidant detoxification,"]
[58.000000000000036,"DCLK1","doublecortin like kinase 1(DCLK1)","Homo sapiens",13,0,6.5,13,"GO:0001764~neuron migration,GO:0006468~protein phosphorylation,GO:0007399~nervous system development,GO:0007417~central nervous system development,GO:0009615~response to virus,GO:0016197~endosomal transport,GO:0018105~peptidyl-serine phosphorylation,GO:0021952~central nervous system projection neuron axonogenesis,GO:0030900~forebrain development,GO:0035556~intracellular signal transduction,GO:0048675~axon extension,GO:0048813~dendrite morphogenesis,GO:1900181~negative regulation of protein localization to nucleus,"]
[58.000000000000036,"GCFC2","GC-rich sequence DNA-binding factor 2(GCFC2)","Homo sapiens",8,5,6.5,13,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000245~spliceosomal complex assembly,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0045892~negative regulation of transcription, DNA-templated,","GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000245~spliceosomal complex assembly,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0045892~negative regulation of transcription, DNA-templated,"]
[59.00000000000002,"AP2M1","adaptor related protein complex 2 mu 1 subunit(AP2M1)","Homo sapiens",12,0,6,12,"GO:0006810~transport,GO:0006886~intracellular protein transport,GO:0007018~microtubule-based movement,GO:0016192~vesicle-mediated transport,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0042059~negative regulation of epidermal growth factor receptor signaling pathway,GO:0048013~ephrin receptor signaling pathway,GO:0050690~regulation of defense response to virus by virus,GO:0060071~Wnt signaling pathway, planar cell polarity pathway,GO:0072583~clathrin-mediated endocytosis,GO:1903077~negative regulation of protein localization to plasma membrane,"]
[59.00000000000002,"CACNA1B","calcium voltage-gated channel subunit alpha1 B(CACNA1B)","Homo sapiens",12,0,6,12,"GO:0006810~transport,GO:0007268~chemical synaptic transmission,GO:0007269~neurotransmitter secretion,GO:0007626~locomotory behavior,GO:0008016~regulation of heart contraction,GO:0008217~regulation of blood pressure,GO:0034765~regulation of ion transmembrane transport,GO:0048265~response to pain,GO:0051899~membrane depolarization,GO:0051924~regulation of calcium ion transport,GO:0070588~calcium ion transmembrane transport,GO:0086010~membrane depolarization during action potential,"]
[59.00000000000002,"COBL","cordon-bleu WH2 repeat protein(COBL)","Homo sapiens",12,0,6,12,"GO:0000578~embryonic axis specification,GO:0001757~somite specification,GO:0001843~neural tube closure,GO:0001889~liver development,GO:0030041~actin filament polymerization,GO:0030903~notochord development,GO:0033504~floor plate development,GO:0048565~digestive tract development,GO:0048669~collateral sprouting in absence of injury,GO:0051639~actin filament network formation,GO:1900006~positive regulation of dendrite development,GO:1900029~positive regulation of ruffle assembly,"]
[59.00000000000002,"SMPD1","sphingomyelin phosphodiesterase 1(SMPD1)","Homo sapiens",12,0,6,12,"GO:0006684~sphingomyelin metabolic process,GO:0006685~sphingomyelin catabolic process,GO:0006687~glycosphingolipid metabolic process,GO:0007165~signal transduction,GO:0007399~nervous system development,GO:0023021~termination of signal transduction,GO:0035307~positive regulation of protein dephosphorylation,GO:0042220~response to cocaine,GO:0042493~response to drug,GO:0043065~positive regulation of apoptotic process,GO:0043407~negative regulation of MAP kinase activity,GO:0046513~ceramide biosynthetic process,"]
[59.00000000000002,"CDH11","cadherin 11(CDH11)","Homo sapiens",6,6,6,12,"GO:0001501~skeletal system development,GO:0001503~ossification,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0021957~corticospinal tract morphogenesis,GO:0034332~adherens junction organization,","GO:0001501~skeletal system development,GO:0001503~ossification,GO:0007155~cell adhesion,GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0021957~corticospinal tract morphogenesis,GO:0034332~adherens junction organization,"]
[59.00000000000002,"GABRA6","gamma-aminobutyric acid type A receptor alpha6 subunit(GABRA6)","Homo sapiens",6,6,6,12,"GO:0006810~transport,GO:0006821~chloride transport,GO:0007165~signal transduction,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0034220~ion transmembrane transport,GO:1902476~chloride transmembrane transport,","GO:0006810~transport,GO:0006821~chloride transport,GO:0007165~signal transduction,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0034220~ion transmembrane transport,GO:1902476~chloride transmembrane transport,"]
[60.00000000000004,"ELOVL6","ELOVL fatty acid elongase 6(ELOVL6)","Homo sapiens",11,0,5.5,11,"GO:0006636~unsaturated fatty acid biosynthetic process,GO:0019367~fatty acid elongation, saturated fatty acid,GO:0030148~sphingolipid biosynthetic process,GO:0034625~fatty acid elongation, monounsaturated fatty acid,GO:0034626~fatty acid elongation, polyunsaturated fatty acid,GO:0035338~long-chain fatty-acyl-CoA biosynthetic process,GO:0042759~long-chain fatty acid biosynthetic process,GO:0042761~very long-chain fatty acid biosynthetic process,"]
[60.00000000000004,"MEIS1","Meis homeobox 1(MEIS1)","Homo sapiens",11,0,5.5,11,"GO:0001525~angiogenesis,GO:0002089~lens morphogenesis in camera-type eye,GO:0006355~regulation of transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0007626~locomotory behavior,GO:0035855~megakaryocyte development,GO:0045638~negative regulation of myeloid cell differentiation,GO:0045665~negative regulation of neuron differentiation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0060216~definitive hemopoiesis,"]
[60.00000000000004,"CUX1","cut like homeobox 1(CUX1)","Homo sapiens",11,0,5.5,11,"GO:0000122~negative regulation of transcription from RNA polymerase II promoter,GO:0000301~retrograde transport, vesicle recycling within Golgi,GO:0006351~transcription, DNA-templated,GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006891~intra-Golgi vesicle-mediated transport,GO:0007275~multicellular organism development,GO:0018108~peptidyl-tyrosine phosphorylation,GO:0048193~Golgi vesicle transport,GO:0050775~positive regulation of dendrite morphogenesis,"]
[60.00000000000004,"MCPH1","microcephalin 1(MCPH1)","Homo sapiens",11,0,5.5,11,"GO:0000132~establishment of mitotic spindle orientation,GO:0010468~regulation of gene expression,GO:0021987~cerebral cortex development,GO:0043549~regulation of kinase activity,GO:0046605~regulation of centrosome cycle,GO:0050727~regulation of inflammatory response,GO:0060348~bone development,GO:0060623~regulation of chromosome condensation,GO:0071539~protein localization to centrosome,GO:0071850~mitotic cell cycle arrest,GO:0097150~neuronal stem cell population maintenance,"]
[60.00000000000004,"PABPN1","poly(A) binding protein nuclear 1(PABPN1)","Homo sapiens",11,0,5.5,11,"GO:0000165~MAPK cascade,GO:0000398~mRNA splicing, via spliceosome,GO:0006369~termination of RNA polymerase II transcription,GO:0006396~RNA processing,GO:0006936~muscle contraction,GO:0016973~poly(A)+ mRNA export from nucleus,GO:0031124~mRNA 3'-end processing,GO:0046778~modification by virus of host mRNA processing,GO:0071222~cellular response to lipopolysaccharide,GO:1904247~positive regulation of polynucleotide adenylyltransferase activity,"]
[60.00000000000004,"PKLR","pyruvate kinase, liver and RBC(PKLR)","Homo sapiens",11,0,5.5,11,"GO:0001666~response to hypoxia,GO:0006754~ATP biosynthetic process,GO:0007584~response to nutrient,GO:0009408~response to heat,GO:0009749~response to glucose,GO:0010226~response to lithium ion,GO:0032869~cellular response to insulin stimulus,GO:0033198~response to ATP,GO:0042866~pyruvate biosynthetic process,GO:0051591~response to cAMP,GO:0061621~canonical glycolysis,"]
[60.00000000000004,"TPP1","tripeptidyl peptidase 1(TPP1)","Homo sapiens",11,0,5.5,11,"GO:0006508~proteolysis,GO:0006629~lipid metabolic process,GO:0007040~lysosome organization,GO:0007399~nervous system development,GO:0007417~central nervous system development,GO:0030163~protein catabolic process,GO:0030855~epithelial cell differentiation,GO:0036498~IRE1-mediated unfolded protein response,GO:0043171~peptide catabolic process,GO:0045453~bone resorption,GO:0050885~neuromuscular process controlling balance,"]
[61.00000000000009,"CEBPD","CCAAT/enhancer binding protein delta(CEBPD)","Homo sapiens",10,0,5,10,"GO:0002244~hematopoietic progenitor cell differentiation,GO:0006351~transcription, DNA-templated,GO:0006366~transcription from RNA polymerase II promoter,GO:0045444~fat cell differentiation,GO:0045669~positive regulation of osteoblast differentiation,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048839~inner ear development,"]
[61.00000000000009,"ELK3","ELK3, ETS transcription factor(ELK3)","Homo sapiens",10,0,5,10,"GO:0001525~angiogenesis,GO:0006366~transcription from RNA polymerase II promoter,GO:0007165~signal transduction,GO:0030154~cell differentiation,GO:0042060~wound healing,GO:0045892~negative regulation of transcription, DNA-templated,GO:0045893~positive regulation of transcription, DNA-templated,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,"]
[61.00000000000009,"NPHS1","NPHS1, nephrin(NPHS1)","Homo sapiens",10,0,5,10,"GO:0007155~cell adhesion,GO:0007254~JNK cascade,GO:0007519~skeletal muscle tissue development,GO:0007520~myoblast fusion,GO:0007588~excretion,GO:0030838~positive regulation of actin filament polymerization,GO:0032836~glomerular basement membrane development,GO:0035418~protein localization to synapse,GO:0044062~regulation of excretion,GO:0072015~glomerular visceral epithelial cell development,"]
[61.00000000000009,"TBR1","T-box, brain 1(TBR1)","Homo sapiens",10,0,5,10,"GO:0001661~conditioned taste aversion,GO:0006351~transcription, DNA-templated,GO:0007420~brain development,GO:0010092~specification of organ identity,GO:0021764~amygdala development,GO:0021902~commitment of neuronal cell to specific neuron type in forebrain,GO:0030902~hindbrain development,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:1902667~regulation of axon guidance,"]
[61.00000000000009,"CACNA1I","calcium voltage-gated channel subunit alpha1 I(CACNA1I)","Homo sapiens",10,0,5,10,"GO:0006810~transport,GO:0007165~signal transduction,GO:0019228~neuronal action potential,GO:0030317~sperm motility,GO:0030431~sleep,GO:0034765~regulation of ion transmembrane transport,GO:0045956~positive regulation of calcium ion-dependent exocytosis,GO:0070509~calcium ion import,GO:0070588~calcium ion transmembrane transport,GO:0086010~membrane depolarization during action potential,"]
[61.00000000000009,"CTNND1","catenin delta 1(CTNND1)","Homo sapiens",10,0,5,10,"GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0007155~cell adhesion,GO:0007420~brain development,GO:0016055~Wnt signaling pathway,GO:0016337~single organismal cell-cell adhesion,GO:0034332~adherens junction organization,GO:0090090~negative regulation of canonical Wnt signaling pathway,"]
[61.00000000000009,"CHRM5","cholinergic receptor muscarinic 5(CHRM5)","Homo sapiens",10,0,5,10,"GO:0001696~gastric acid secretion,GO:0007197~adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway,GO:0007207~phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway,GO:0007213~G-protein coupled acetylcholine receptor signaling pathway,GO:0007271~synaptic transmission, cholinergic,GO:0008283~cell proliferation,GO:0015872~dopamine transport,GO:0019226~transmission of nerve impulse,GO:0060304~regulation of phosphatidylinositol dephosphorylation,"]
[61.00000000000009,"GABRB1","gamma-aminobutyric acid type A receptor beta1 subunit(GABRB1)","Homo sapiens",10,0,5,10,"GO:0006810~transport,GO:0006811~ion transport,GO:0007165~signal transduction,GO:0009636~response to toxic substance,GO:0021954~central nervous system neuron development,GO:0032570~response to progesterone,GO:0034220~ion transmembrane transport,GO:0042698~ovulation cycle,GO:0071420~cellular response to histamine,GO:1902476~chloride transmembrane transport,"]
[61.00000000000009,"GABRG2","gamma-aminobutyric acid type A receptor gamma2 subunit(GABRG2)","Homo sapiens",10,0,5,10,"GO:0006810~transport,GO:0006821~chloride transport,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0009791~post-embryonic development,GO:0030534~adult behavior,GO:0034220~ion transmembrane transport,GO:0051932~synaptic transmission, GABAergic,GO:0071420~cellular response to histamine,GO:1902476~chloride transmembrane transport,"]
[61.00000000000009,"SLC2A1","solute carrier family 2 member 1(SLC2A1)","Homo sapiens",10,0,5,10,"GO:0005989~lactose biosynthetic process,GO:0006461~protein complex assembly,GO:0006970~response to osmotic stress,GO:0015758~glucose transport,GO:0019852~L-ascorbic acid metabolic process,GO:0042149~cellular response to glucose starvation,GO:0042908~xenobiotic transport,GO:0050796~regulation of insulin secretion,GO:0070837~dehydroascorbic acid transport,GO:1904659~glucose transmembrane transport,"]
[61.00000000000009,"RUNX1T1","RUNX1 translocation partner 1(RUNX1T1)","Homo sapiens",6,4,5,10,"GO:0006091~generation of precursor metabolites and energy,GO:0006351~transcription, DNA-templated,GO:0045599~negative regulation of fat cell differentiation,GO:0045892~negative regulation of transcription, DNA-templated,","GO:0006091~generation of precursor metabolites and energy,GO:0006351~transcription, DNA-templated,GO:0045599~negative regulation of fat cell differentiation,GO:0045892~negative regulation of transcription, DNA-templated,"]
[61.00000000000009,"MAOA","monoamine oxidase A(MAOA)","Homo sapiens",5,5,5,10,"GO:0006576~cellular biogenic amine metabolic process,GO:0042133~neurotransmitter metabolic process,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0055114~oxidation-reduction process,","GO:0006576~cellular biogenic amine metabolic process,GO:0042133~neurotransmitter metabolic process,GO:0042135~neurotransmitter catabolic process,GO:0042420~dopamine catabolic process,GO:0055114~oxidation-reduction process,"]
[61.00000000000009,"PCNT","pericentrin(PCNT)","Homo sapiens",5,5,5,10,"GO:0000086~G2/M transition of mitotic cell cycle,GO:0000226~microtubule cytoskeleton organization,GO:0007052~mitotic spindle organization,GO:0042384~cilium assembly,GO:0090316~positive regulation of intracellular protein transport,","GO:0000086~G2/M transition of mitotic cell cycle,GO:0000226~microtubule cytoskeleton organization,GO:0007052~mitotic spindle organization,GO:0042384~cilium assembly,GO:0090316~positive regulation of intracellular protein transport,"]
[61.00000000000009,"SLC2A3","solute carrier family 2 member 3(SLC2A3)","Homo sapiens",5,5,5,10,"GO:0005975~carbohydrate metabolic process,GO:0015758~glucose transport,GO:0019852~L-ascorbic acid metabolic process,GO:0070837~dehydroascorbic acid transport,GO:1904659~glucose transmembrane transport,","GO:0005975~carbohydrate metabolic process,GO:0015758~glucose transport,GO:0019852~L-ascorbic acid metabolic process,GO:0070837~dehydroascorbic acid transport,GO:1904659~glucose transmembrane transport,"]
[61.00000000000009,"STS","steroid sulfatase (microsomal), isozyme S(STS)","Homo sapiens",5,5,5,10,"GO:0006687~glycosphingolipid metabolic process,GO:0006706~steroid catabolic process,GO:0007565~female pregnancy,GO:0008544~epidermis development,GO:0043687~post-translational protein modification,","GO:0006687~glycosphingolipid metabolic process,GO:0006706~steroid catabolic process,GO:0007565~female pregnancy,GO:0008544~epidermis development,GO:0043687~post-translational protein modification,"]
[62.00000000000011,"USO1","USO1 vesicle transport factor(USO1)","Homo sapiens",9,0,4.5,9,"GO:0006886~intracellular protein transport,GO:0006888~ER to Golgi vesicle-mediated transport,GO:0007030~Golgi organization,GO:0045056~transcytosis,GO:0048208~COPII vesicle coating,GO:0048211~Golgi vesicle docking,GO:0048280~vesicle fusion with Golgi apparatus,GO:0061025~membrane fusion,GO:0098609~cell-cell adhesion,"]
[62.00000000000011,"ELN","elastin(ELN)","Homo sapiens",9,0,4.5,9,"GO:0007519~skeletal muscle tissue development,GO:0007585~respiratory gaseous exchange,GO:0008015~blood circulation,GO:0008283~cell proliferation,GO:0009887~organ morphogenesis,GO:0022617~extracellular matrix disassembly,GO:0030198~extracellular matrix organization,GO:0030833~regulation of actin filament polymerization,GO:0043149~stress fiber assembly,"]
[62.00000000000011,"GABRA1","gamma-aminobutyric acid type A receptor alpha1 subunit(GABRA1)","Homo sapiens",9,0,4.5,9,"GO:0006810~transport,GO:0006811~ion transport,GO:0006821~chloride transport,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0034220~ion transmembrane transport,GO:0051932~synaptic transmission, GABAergic,GO:0071420~cellular response to histamine,GO:1902476~chloride transmembrane transport,"]
[62.00000000000011,"GRIA1","glutamate ionotropic receptor AMPA type subunit 1(GRIA1)","Homo sapiens",9,0,4.5,9,"GO:0006888~ER to Golgi vesicle-mediated transport,GO:0007165~signal transduction,GO:0007268~chemical synaptic transmission,GO:0007616~long-term memory,GO:0031623~receptor internalization,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,GO:0048208~COPII vesicle coating,GO:0060292~long term synaptic depression,"]
[62.00000000000011,"ENPEP","glutamyl aminopeptidase(ENPEP)","Homo sapiens",9,0,4.5,9,"GO:0001525~angiogenesis,GO:0002003~angiotensin maturation,GO:0002005~angiotensin catabolic process in blood,GO:0003081~regulation of systemic arterial blood pressure by renin-angiotensin,GO:0007267~cell-cell signaling,GO:0008283~cell proliferation,GO:0016477~cell migration,GO:0032835~glomerulus development,GO:0043171~peptide catabolic process,"]
[62.00000000000011,"HCN1","hyperpolarization activated cyclic nucleotide gated potassium channel 1(HCN1)","Homo sapiens",9,0,4.5,9,"GO:0006813~potassium ion transport,GO:0034765~regulation of ion transmembrane transport,GO:0035725~sodium ion transmembrane transport,GO:0042391~regulation of membrane potential,GO:0045176~apical protein localization,GO:0046549~retinal cone cell development,GO:0060078~regulation of postsynaptic membrane potential,GO:0071320~cellular response to cAMP,GO:0071805~potassium ion transmembrane transport,"]
[62.00000000000011,"PTPRD","protein tyrosine phosphatase, receptor type D(PTPRD)","Homo sapiens",9,0,4.5,9,"GO:0006470~protein dephosphorylation,GO:0006796~phosphate-containing compound metabolic process,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0007185~transmembrane receptor protein tyrosine phosphatase signaling pathway,GO:0007268~chemical synaptic transmission,GO:0030182~neuron differentiation,GO:0035335~peptidyl-tyrosine dephosphorylation,GO:0050775~positive regulation of dendrite morphogenesis,GO:0097105~presynaptic membrane assembly,"]
[62.00000000000011,"RCC1","regulator of chromosome condensation 1(RCC1)","Homo sapiens",9,0,4.5,9,"GO:0000082~G1/S transition of mitotic cell cycle,GO:0007052~mitotic spindle organization,GO:0007059~chromosome segregation,GO:0007067~mitotic nuclear division,GO:0007088~regulation of mitotic nuclear division,GO:0016032~viral process,GO:0043547~positive regulation of GTPase activity,GO:0051225~spindle assembly,GO:0051301~cell division,"]
[62.00000000000011,"SCN8A","sodium voltage-gated channel alpha subunit 8(SCN8A)","Homo sapiens",9,0,4.5,9,"GO:0006814~sodium ion transport,GO:0007399~nervous system development,GO:0007422~peripheral nervous system development,GO:0019228~neuronal action potential,GO:0034765~regulation of ion transmembrane transport,GO:0035725~sodium ion transmembrane transport,GO:0042552~myelination,GO:0060078~regulation of postsynaptic membrane potential,GO:0086010~membrane depolarization during action potential,"]
[62.00000000000011,"GRM3","glutamate metabotropic receptor 3(GRM3)","Homo sapiens",5,4,4.5,9,"GO:0007194~negative regulation of adenylate cyclase activity,GO:0007196~adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0051966~regulation of synaptic transmission, glutamatergic,","GO:0007194~negative regulation of adenylate cyclase activity,GO:0007196~adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0051966~regulation of synaptic transmission, glutamatergic,"]
[63.000000000000135,"POLR3B","RNA polymerase III subunit B(POLR3B)","Homo sapiens",8,0,4,8,"GO:0006351~transcription, DNA-templated,GO:0006383~transcription from RNA polymerase III promoter,GO:0032481~positive regulation of type I interferon production,GO:0032728~positive regulation of interferon-beta production,GO:0045087~innate immune response,GO:0045089~positive regulation of innate immune response,GO:0051607~defense response to virus,"]
[63.000000000000135,"SUPT3H","SPT3 homolog, SAGA and STAGA complex component(SUPT3H)","Homo sapiens",8,0,4,8,"GO:0006355~regulation of transcription, DNA-templated,GO:0006357~regulation of transcription from RNA polymerase II promoter,GO:0006366~transcription from RNA polymerase II promoter,GO:0016578~histone deubiquitination,GO:0043966~histone H3 acetylation,GO:0045893~positive regulation of transcription, DNA-templated,"]
[63.000000000000135,"EPM2A","epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)(EPM2A)","Homo sapiens",8,0,4,8,"GO:0005977~glycogen metabolic process,GO:0005978~glycogen biosynthetic process,GO:0006470~protein dephosphorylation,GO:0006914~autophagy,GO:0007399~nervous system development,GO:0016239~positive regulation of macroautophagy,GO:0032007~negative regulation of TOR signaling,GO:0046959~habituation,"]
[63.000000000000135,"FGF14","fibroblast growth factor 14(FGF14)","Homo sapiens",8,0,4,8,"GO:0007165~signal transduction,GO:0007254~JNK cascade,GO:0007267~cell-cell signaling,GO:0007399~nervous system development,GO:0048167~regulation of synaptic plasticity,GO:0060078~regulation of postsynaptic membrane potential,GO:1901843~positive regulation of high voltage-gated calcium channel activity,GO:1903421~regulation of synaptic vesicle recycling,"]
[63.000000000000135,"FLNB","filamin B(FLNB)","Homo sapiens",8,0,4,8,"GO:0003334~keratinocyte development,GO:0003382~epithelial cell morphogenesis,GO:0007016~cytoskeletal anchoring at plasma membrane,GO:0007165~signal transduction,GO:0007519~skeletal muscle tissue development,GO:0030036~actin cytoskeleton organization,GO:0030154~cell differentiation,GO:0098609~cell-cell adhesion,"]
[63.000000000000135,"YWHAQ","tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta(YWHAQ)","Homo sapiens",8,0,4,8,"GO:0006605~protein targeting,GO:0007264~small GTPase mediated signal transduction,GO:0021762~substantia nigra development,GO:0034766~negative regulation of ion transmembrane transport,GO:0045892~negative regulation of transcription, DNA-templated,GO:0061024~membrane organization,GO:1900740~positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,"]
[63.000000000000135,"CADM2","cell adhesion molecule 2(CADM2)","Homo sapiens",4,4,4,8,"GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0008037~cell recognition,GO:0034332~adherens junction organization,","GO:0007156~homophilic cell adhesion via plasma membrane adhesion molecules,GO:0007157~heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules,GO:0008037~cell recognition,GO:0034332~adherens junction organization,"]
[63.000000000000135,"KCNIP4","potassium voltage-gated channel interacting protein 4(KCNIP4)","Homo sapiens",4,4,4,8,"GO:0061337~cardiac conduction,GO:0071805~potassium ion transmembrane transport,GO:0072659~protein localization to plasma membrane,GO:1901379~regulation of potassium ion transmembrane transport,","GO:0061337~cardiac conduction,GO:0071805~potassium ion transmembrane transport,GO:0072659~protein localization to plasma membrane,GO:1901379~regulation of potassium ion transmembrane transport,"]
[63.000000000000135,"TDO2","tryptophan 2,3-dioxygenase(TDO2)","Homo sapiens",4,4,4,8,"GO:0006569~tryptophan catabolic process,GO:0019441~tryptophan catabolic process to kynurenine,GO:0019442~tryptophan catabolic process to acetyl-CoA,GO:0055114~oxidation-reduction process,","GO:0006569~tryptophan catabolic process,GO:0019441~tryptophan catabolic process to kynurenine,GO:0019442~tryptophan catabolic process to acetyl-CoA,GO:0055114~oxidation-reduction process,"]
[64.00000000000016,"PRDM9","PR/SET domain 9(PRDM9)","Homo sapiens",7,0,3.5,7,"GO:0006311~meiotic gene conversion,GO:0006351~transcription, DNA-templated,GO:0006355~regulation of transcription, DNA-templated,GO:0010845~positive regulation of reciprocal meiotic recombination,GO:0034968~histone lysine methylation,"]
[64.00000000000016,"SHC2","SHC adaptor protein 2(SHC2)","Homo sapiens",7,0,3.5,7,"GO:0000165~MAPK cascade,GO:0000187~activation of MAPK activity,GO:0007169~transmembrane receptor protein tyrosine kinase signaling pathway,GO:0007265~Ras protein signal transduction,GO:0035556~intracellular signal transduction,GO:0043547~positive regulation of GTPase activity,GO:0048010~vascular endothelial growth factor receptor signaling pathway,"]
[64.00000000000016,"GPC6","glypican 6(GPC6)","Homo sapiens",7,0,3.5,7,"GO:0001523~retinoid metabolic process,GO:0006024~glycosaminoglycan biosynthetic process,GO:0006027~glycosaminoglycan catabolic process,GO:0016477~cell migration,GO:0030203~glycosaminoglycan metabolic process,GO:0060071~Wnt signaling pathway, planar cell polarity pathway,"]
[64.00000000000016,"LGI1","leucine rich glioma inactivated 1(LGI1)","Homo sapiens",7,0,3.5,7,"GO:0007399~nervous system development,GO:0007411~axon guidance,GO:0008283~cell proliferation,GO:0030307~positive regulation of cell growth,GO:0031175~neuron projection development,GO:0050806~positive regulation of synaptic transmission,GO:0051260~protein homooligomerization,"]
[64.00000000000016,"HLA-DQA1","major histocompatibility complex, class II, DQ alpha 1(HLA-DQA1)","Homo sapiens",7,0,3.5,7,"GO:0002504~antigen processing and presentation of peptide or polysaccharide antigen via MHC class II,GO:0006955~immune response,GO:0019882~antigen processing and presentation,GO:0019886~antigen processing and presentation of exogenous peptide antigen via MHC class II,GO:0031295~T cell costimulation,GO:0050852~T cell receptor signaling pathway,GO:0060333~interferon-gamma-mediated signaling pathway,"]
[64.00000000000016,"PRODH","proline dehydrogenase 1(PRODH)","Homo sapiens",7,0,3.5,7,"GO:0006560~proline metabolic process,GO:0006562~proline catabolic process,GO:0008631~intrinsic apoptotic signaling pathway in response to oxidative stress,GO:0010133~proline catabolic process to glutamate,GO:0010942~positive regulation of cell death,GO:0019470~4-hydroxyproline catabolic process,GO:0055114~oxidation-reduction process,"]
[64.00000000000016,"SRPX2","sushi repeat containing protein, X-linked 2(SRPX2)","Homo sapiens",7,0,3.5,7,"GO:0001525~angiogenesis,GO:0016337~single organismal cell-cell adhesion,GO:0042325~regulation of phosphorylation,GO:0048870~cell motility,GO:0051965~positive regulation of synapse assembly,GO:0071625~vocalization behavior,GO:0090050~positive regulation of cell migration involved in sprouting angiogenesis,"]
[65.00000000000013,"GSX1","GS homeobox 1(GSX1)","Homo sapiens",6,0,3,6,"GO:0006366~transcription from RNA polymerase II promoter,GO:0021527~spinal cord association neuron differentiation,GO:0021854~hypothalamus development,GO:0021984~adenohypophysis development,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0048663~neuron fate commitment,"]
[65.00000000000013,"SEC14L2","SEC14 like lipid binding 2(SEC14L2)","Homo sapiens",6,0,3,6,"GO:0006351~transcription, DNA-templated,GO:0006810~transport,GO:0045540~regulation of cholesterol biosynthetic process,GO:0045893~positive regulation of transcription, DNA-templated,"]
[65.00000000000013,"SERPINA3","serpin family A member 3(SERPINA3)","Homo sapiens",6,0,3,6,"GO:0002576~platelet degranulation,GO:0006953~acute-phase response,GO:0006954~inflammatory response,GO:0010951~negative regulation of endopeptidase activity,GO:0019216~regulation of lipid metabolic process,GO:0030277~maintenance of gastrointestinal epithelium,"]
[65.00000000000013,"SCN3A","sodium voltage-gated channel alpha subunit 3(SCN3A)","Homo sapiens",6,0,3,6,"GO:0006814~sodium ion transport,GO:0019228~neuronal action potential,GO:0034765~regulation of ion transmembrane transport,GO:0035725~sodium ion transmembrane transport,GO:0060078~regulation of postsynaptic membrane potential,GO:0086010~membrane depolarization during action potential,"]
[65.00000000000013,"SPATA13","spermatogenesis associated 13(SPATA13)","Homo sapiens",6,0,3,6,"GO:0016477~cell migration,GO:0030032~lamellipodium assembly,GO:0030334~regulation of cell migration,GO:0035023~regulation of Rho protein signal transduction,GO:0043547~positive regulation of GTPase activity,GO:0046847~filopodium assembly,"]
[65.00000000000013,"GABBR1","gamma-aminobutyric acid type B receptor subunit 1(GABBR1)","Homo sapiens",3,3,3,6,"GO:0007193~adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007214~gamma-aminobutyric acid signaling pathway,","GO:0007193~adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway,GO:0007194~negative regulation of adenylate cyclase activity,GO:0007214~gamma-aminobutyric acid signaling pathway,"]
[65.00000000000013,"MOG","myelin oligodendrocyte glycoprotein(MOG)","Homo sapiens",3,3,3,6,"GO:0007155~cell adhesion,GO:0007417~central nervous system development,GO:0046718~viral entry into host cell,","GO:0007155~cell adhesion,GO:0007417~central nervous system development,GO:0046718~viral entry into host cell,"]
[66.00000000000014,"AFF2","AF4/FMR2 family member 2(AFF2)","Homo sapiens",5,0,2.5,5,"GO:0006397~mRNA processing,GO:0007420~brain development,GO:0007611~learning or memory,GO:0008380~RNA splicing,GO:0043484~regulation of RNA splicing,"]
[66.00000000000014,"AUTS2","autism susceptibility candidate 2(AUTS2)","Homo sapiens",5,0,2.5,5,"GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0051571~positive regulation of histone H3-K4 methylation,GO:0060013~righting reflex,GO:0098582~innate vocalization behavior,GO:2000620~positive regulation of histone H4-K16 acetylation,"]
[66.00000000000014,"GRIA4","glutamate ionotropic receptor AMPA type subunit 4(GRIA4)","Homo sapiens",5,0,2.5,5,"GO:0006810~transport,GO:0007215~glutamate receptor signaling pathway,GO:0007268~chemical synaptic transmission,GO:0034220~ion transmembrane transport,GO:0035235~ionotropic glutamate receptor signaling pathway,"]
[66.00000000000014,"IER3","immediate early response 3(IER3)","Homo sapiens",5,0,2.5,5,"GO:0006915~apoptotic process,GO:0009653~anatomical structure morphogenesis,GO:0014066~regulation of phosphatidylinositol 3-kinase signaling,GO:0043066~negative regulation of apoptotic process,GO:2001020~regulation of response to DNA damage stimulus,"]
[66.00000000000014,"NXF1","nuclear RNA export factor 1(NXF1)","Homo sapiens",5,0,2.5,5,"GO:0006405~RNA export from nucleus,GO:0006406~mRNA export from nucleus,GO:0016032~viral process,GO:0016973~poly(A)+ mRNA export from nucleus,GO:0051028~mRNA transport,"]
[67.00000000000009,"CELF2","CUGBP, Elav-like family member 2(CELF2)","Homo sapiens",4,0,2,4,"GO:0006376~mRNA splice site selection,GO:0006396~RNA processing,GO:0006397~mRNA processing,GO:0008016~regulation of heart contraction,"]
[67.00000000000009,"CSE1L","chromosome segregation 1 like(CSE1L)","Homo sapiens",4,0,2,4,"GO:0006606~protein import into nucleus,GO:0006611~protein export from nucleus,GO:0006915~apoptotic process,GO:0008283~cell proliferation,"]
[67.00000000000009,"CDK8","cyclin dependent kinase 8(CDK8)","Homo sapiens",4,0,2,4,"GO:0006367~transcription initiation from RNA polymerase II promoter,GO:0006468~protein phosphorylation,GO:0045944~positive regulation of transcription from RNA polymerase II promoter,GO:0051726~regulation of cell cycle,"]
[67.00000000000009,"GABRG3","gamma-aminobutyric acid type A receptor gamma3 subunit(GABRG3)","Homo sapiens",4,0,2,4,"GO:0006821~chloride transport,GO:0007214~gamma-aminobutyric acid signaling pathway,GO:0034220~ion transmembrane transport,GO:1902476~chloride transmembrane transport,"]
[67.00000000000009,"NGDN","neuroguidin(NGDN)","Homo sapiens",4,0,2,4,"GO:0000462~maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),GO:0006417~regulation of translation,"]
[67.00000000000009,"DIRAS2","DIRAS family GTPase 2(DIRAS2)","Homo sapiens",2,2,2,4,"GO:0007264~small GTPase mediated signal transduction,GO:0043406~positive regulation of MAP kinase activity,","GO:0007264~small GTPase mediated signal transduction,GO:0043406~positive regulation of MAP kinase activity,"]
[67.00000000000009,"KIAA0319","KIAA0319(KIAA0319)","Homo sapiens",2,2,2,4,"GO:0001764~neuron migration,GO:2000171~negative regulation of dendrite development,","GO:0001764~neuron migration,GO:2000171~negative regulation of dendrite development,"]
[67.00000000000009,"CNTN5","contactin 5(CNTN5)","Homo sapiens",2,2,2,4,"GO:0007155~cell adhesion,GO:0007605~sensory perception of sound,","GO:0007155~cell adhesion,GO:0007605~sensory perception of sound,"]
[67.00000000000009,"FLNC","filamin C(FLNC)","Homo sapiens",2,2,2,4,"GO:0034329~cell junction assembly,GO:0048747~muscle fiber development,","GO:0034329~cell junction assembly,GO:0048747~muscle fiber development,"]
[67.00000000000009,"NIPA2","non imprinted in Prader-Willi/Angelman syndrome 2(NIPA2)","Homo sapiens",2,2,2,4,"GO:0015693~magnesium ion transport,GO:1903830~magnesium ion transmembrane transport,","GO:0015693~magnesium ion transport,GO:1903830~magnesium ion transmembrane transport,"]
[68.00000000000009,"NIPA1","non imprinted in Prader-Willi/Angelman syndrome 1(NIPA1)","Homo sapiens",3,0,1.5,3,"GO:0015693~magnesium ion transport,GO:0055085~transmembrane transport,GO:1903830~magnesium ion transmembrane transport,"]
[68.00000000000009,"TUBB2B","tubulin beta 2B class IIb(TUBB2B)","Homo sapiens",3,0,1.5,3,"GO:0001764~neuron migration,GO:0007010~cytoskeleton organization,GO:0007017~microtubule-based process,"]
[69.00000000000006,"CLUH","clustered mitochondria homolog(CLUH)","Homo sapiens",2,0,1,2,"GO:0007005~mitochondrion organization,GO:0048312~intracellular distribution of mitochondria,"]
[69.00000000000006,"MCTP2","multiple C2 and transmembrane domain containing 2(MCTP2)","Homo sapiens",2,0,1,2,"GO:0007275~multicellular organism development,GO:0019722~calcium-mediated signaling,"]
[69.00000000000006,"MOBP","myelin-associated oligodendrocyte basic protein(MOBP)","Homo sapiens",2,0,1,2,"GO:0007399~nervous system development,GO:0030050~vesicle transport along actin filament,"]
[69.00000000000006,"DLGAP1","DLG associated protein 1(DLGAP1)","Homo sapiens",1,1,1,2,"GO:0007268~chemical synaptic transmission,","GO:0007268~chemical synaptic transmission,"]
[69.00000000000006,"CNTNAP5","contactin associated protein like 5(CNTNAP5)","Homo sapiens",1,1,1,2,"GO:0007155~cell adhesion,","GO:0007155~cell adhesion,"]
[69.00000000000006,"PRTG","protogenin(PRTG)","Homo sapiens",1,1,1,2,"GO:0007275~multicellular organism development,","GO:0007275~multicellular organism development,"]
[69.00000000000006,"ZNF385D","zinc finger protein 385D(ZNF385D)","Homo sapiens",1,1,1,2,"GO:0072332~intrinsic apoptotic signaling pathway by p53 class mediator,","GO:0072332~intrinsic apoptotic signaling pathway by p53 class mediator,"]
[70.00000000000006,"CSN1S1","casein alpha s1(CSN1S1)","Homo sapiens",1,0,0.5,1,"GO:0055085~transmembrane transport,"]
[70.00000000000006,"DCDC1","doublecortin domain containing 1(DCDC1)","Homo sapiens",1,0,0.5,1,"GO:0035556~intracellular signal transduction,"]
[70.00000000000006,"EBPL","emopamil binding protein like(EBPL)","Homo sapiens",1,0,0.5,1,"GO:0016125~sterol metabolic process,"]
[70.00000000000006,"ERMP1","endoplasmic reticulum metallopeptidase 1(ERMP1)","Homo sapiens",1,0,0.5,1,"GO:0006508~proteolysis,"]
[70.00000000000006,"PVALB","parvalbumin(PVALB)","Homo sapiens",1,0,0.5,1,"GO:0051480~regulation of cytosolic calcium ion concentration,"]
[70.00000000000006,"KCNT1","potassium sodium-activated channel subfamily T member 1(KCNT1)","Homo sapiens",1,0,0.5,1,"GO:0071805~potassium ion transmembrane transport,"]
[70.00000000000006,"TMEM132D","transmembrane protein 132D(TMEM132D)","Homo sapiens",1,0,0.5,1,"GO:0010923~negative regulation of phosphatase activity,"]
[70.00000000000006,"VPS13B","vacuolar protein sorting 13 homolog B(VPS13B)","Homo sapiens",1,0,0.5,1,"GO:0015031~protein transport,"]
[71,"PRKN"]
[71,"ZNF804A"]
[71,"DEL15Q11.2"]
[71,"DNAAF4"]
[71,"FRAXA"]
[71,"NALF1"]
[71,"RSL24D1P11"]
[71,"SLC25A5P2"]
[71,"RPL38P2"]
[71,"RPS3AP1"]
[71,"NEXMIF"]
[71,"MIR1253"]
[71,"CCDC92B"]
[71,"LOC105371592"]
[71,"CFAP47"]
[71,"STAG3L4"]
[71,"SETBP1"]
[71,"JRK"]
[71,"OTOL1"]
[71,"KRT18P24"]
[71,"RPL18P7"]
[71,"PRB1"]
[71,"ERICD"]
[71,"DIGIT"]
[71,"SAP2"]
[71,"Fh1"]
[71,"SPF"]
[71,"DAT"]
[71,"SCK"]
[71,"VDP"]
[71,"SPCA2"]
[71,"Aromatase"]