{"text_format":"3","workbook":"xls","n_sheets":1,"sheets":["Supplementary Table 5"],"not_rendered":{"external_links":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Supplementary Table 5","index":0,"n_rows":45,"n_cols":5,"rows_kept":45,"flags":["formulas_cached_only"]}
["Supplementary Table 5. Impact of F11R on signaling hallmarkers"]
[]
["© 2000-2022 QIAGEN. All rights reserved."]
["Ingenuity Canonical Pathways"," -log(p-value)","Ratio","z-score","Molecules"]
["EIF2 Signaling",16.2,0.545,7.44,"ACTA2,ACTG2,AGO1,AGO2,AGO3,AKT2,AKT3,ATF4,ATF5,BCL2,EIF1,EIF1AY,EIF2A,EIF2S1,EIF2S2,EIF2S3,EIF3A,EIF3E,EIF3F,EIF3H,EIF3K,EIF3M,EIF4E,EIF4G2,EIF4G3,EIF5,EIF5B,GSK3B,HNRNPA1,HSPA5,IGF1R,INSR,KRAS,MAP2K2,MAPK1,MYCN,NKX6-2,PABPC1,PAIP1,PDPK1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPP1CA,PTBP1,RAP1A,RAP2A,RAP2B,RPL10,RPL10A,RPL12,RPL13,RPL13A,RPL14,RPL15,RPL18,RPL18A,RPL19,RPL22,RPL22L1,RPL23,RPL23A,RPL24,RPL26L1,RPL27,RPL27A,RPL28,RPL29,RPL3,RPL30,RPL31,RPL32,RPL34,RPL35,RPL35A,RPL36,RPL36A,RPL37,RPL37A,RPL38,RPL39,RPL4,RPL41,RPL5,RPL7,RPL7A,RPL7L1,RPL8,RPLP0,RPLP2,RPS10,RPS11,RPS12,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS27A,RPS28,RPS29,RPS3A,RPS4X,RPS4Y1,RPS5,RPS9,RPSA,RRAS2,SOS1,UBA52,VEGFA,XIAP"]
["mTOR Signaling",7.96,0.462,4.064,"AKT1S1,AKT2,AKT3,CDC42,DGKZ,DIRAS3,EIF3A,EIF3E,EIF3F,EIF3H,EIF3K,EIF3M,EIF4B,EIF4E,EIF4EBP1,EIF4EBP2,EIF4G2,EIF4G3,FNBP1,GNB1L,GPLD1,INSR,IRS1,KRAS,MAPK1,MAPKAP1,MTOR,NAPEPLD,PDPK1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLD1,PLD4,PLD6,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKCA,PRKCB,PRKCI,PRKD3,PROK1,PTPA,RAP1A,RAP2A,RAP2B,RHEB,RHOA,RHOB,RHOBTB2,RHOD,RHOJ,RHOQ,RHOT1,RHOT2,RPS10,RPS11,RPS12,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS27A,RPS28,RPS29,RPS3A,RPS4X,RPS4Y1,RPS5,RPS6KA5,RPS6KA6,RPS9,RPSA,RRAS2,STK11,TSC1,VEGFA"]
["Regulation of eIF4 and p70S6K Signaling",7.66,0.475,2.335,"AGO1,AGO2,AGO3,AKT2,AKT3,EIF1,EIF1AY,EIF2A,EIF2S1,EIF2S2,EIF2S3,EIF3A,EIF3E,EIF3F,EIF3H,EIF3K,EIF3M,EIF4E,EIF4EBP1,EIF4EBP2,EIF4G2,EIF4G3,IRS1,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,KRAS,MAP2K2,MAPK1,MAPK12,MAPK14,MTOR,PABPC1,PAIP1,PDPK1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PTPA,RAP1A,RAP2A,RAP2B,RPS10,RPS11,RPS12,RPS14,RPS15,RPS15A,RPS16,RPS18,RPS19,RPS2,RPS20,RPS21,RPS23,RPS24,RPS27A,RPS28,RPS29,RPS3A,RPS4X,RPS4Y1,RPS5,RPS9,RPSA,RRAS2,SOS1"]
["Senescence Pathway",7.53,0.428,6.679,"ACVR1B,ACVR1C,ACVR2B,AKT2,AKT3,ANAPC1,ANAPC10,ANAPC5,ASXL1,ASXL2,ATM,BMPR2,BRAF,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CAPN1,CAPN2,CAPN8,CAPN9,CAPNS1,CCNE1,CCNE2,CDC23,CDC25A,CDK2,CDK4,CDKN2A,CDKN2B,CHEK1,CHUK,CREBBP,DLD,E2F1,E2F2,E2F3,E2F6,EIF4E,EIF4EBP1,ELF3,ELF5,EP400,ETS2,EZH2,FOXO4,FZR1,GATA4,HBP1,IL1A,ING1,ITPR2,ITSN2,KRAS,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MAPK12,MAPK14,MAPK15,MAPK4,MDM2,MRE11,MTOR,NBN,NF1,NFATC2,NFATC3,PCGF1,PCGF6,PDK2,PDK3,PDK4,PHF19,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPM1L,PPP1CA,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PTEN,PTPA,RAP1A,RAP2A,RAP2B,RBL1,RPS6KA5,RRAS2,SMAD2,SMAD4,SMAD5,SMAD6,SMAD9,SQSTM1,TGFB1,TGFB2,TGFB3,TGFBR1,TLR2,TP53,VHL,YPEL3,ZFP36L1"]
["Synaptogenesis Signaling Pathway",6.98,0.417,9.749,"ACTR3,ADCY1,ADCY2,ADCY3,ADCY5,AFDN,AKT2,AKT3,AP2A1,AP2S1,APOE,ARHGEF7,ARPC4,ARPC5,ATF2,ATF4,BDNF,BRAF,CACNB4,CACNG1,CADM1,CALM1 (includes others),CDC42,CDH1,CDH11,CDH18,CDH23,CDH26,CDH6,CDH8,CFL1,CLASP2,CNTNAP2,CPLX3,CREB1,CREBBP,CRK,CRKL,CTNNB1,DAB1,EFNA5,EFNB1,EFNB3,EIF4EBP1,EIF4EBP2,EPHA10,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB6,GOSR2,GPAA1,GRIA3,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN3A,GRM1,GRM5,GRM8,GSK3B,HSPA8,ITPR1,ITSN1,ITSN2,KALRN,KRAS,LRP1,LRP8,LRRTM2,MAP1B,MAPK1,MAPK14,MTOR,NAP1L1,NAP1L4,NAPB,NLGN4Y,NRXN1,NRXN2,NSF,NTRK2,PAFAH1B1,PAK1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCG2,PRKAG2,PRKAR1A,PRKAR2A,RAB3A,RAB5C,RAP1A,RAP2A,RAP2B,RAPGEF1,RASGRF1,RHOA,RRAS2,SGTA,SHC3,SHE,SHF,SOS1,SRC,STXBP4,STXBP6,SYNGAP1,SYT11,SYT12,SYT16,SYT2,SYT5,SYT7,SYT9,THBS2,THBS4,TLN1,UNC13A,VTI1A,WASL"]
["Hepatic Fibrosis Signaling Pathway",6.59,0.394,9.063,"ACTA2,ACVR1B,ACVR1C,ACVR2B,AKT2,AKT3,ATF2,ATF4,AXIN1,BCL2,BMPR2,BRAF,BRD4,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CCL3,CCN2,CDC42,CHUK,CNR1,COL10A1,COL11A2,COL18A1,COL1A1,COL1A2,COL2A1,CREB1,CREBBP,CSNK1E,CSNK1G1,CSNK1G3,CTNNB1,CYBB,DIRAS3,EDN1,EDNRA,EZH2,FLT1,FNBP1,FOXO1,FOXO4,FZD3,FZD5,FZD9,GSK3B,HNF1A,IL17A,IL18RAP,IL1A,IL1R1,IL1R2,IL1RAP,IL1RAPL2,IL1RL1,IL36A,IL37,IRAK1,IRAK3,IRS2,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,JAK2,KLF9,KRAS,LEF1,LEP,LRP1,LRP5,LRP6,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MMP13,MTOR,MYL1,MYL12A,MYL2,MYL6,MYL9,MYLK,MYLK2,MYLK3,NCF1,NFKBIB,NFKBID,NOX1,PDCD4,PDGFB,PDGFRA,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCG2,PPARG,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PROK1,PTCH1,PTEN,PTK2,RAP1A,RAP2A,RAP2B,RHOA,RHOB,RHOBTB2,RHOD,RHOJ,RHOQ,RHOT1,RHOT2,RRAS2,SDHA,SMAD2,SMAD4,SMO,SOS1,TCF3,TCF7L2,TF,TFRC,TGFB1,TGFB2,TGFB3,TGFBR1,TIRAP,TNF,TTN,VEGFA,WNT16,WNT2,WNT4,WNT7B,ZNF875"]
["Dopamine-DARPP32 Feedback in cAMP Signaling",5.99,0.448,6.64,"ADCY1,ADCY2,ADCY3,ADCY5,ATF1,ATF2,ATF4,ATP2A1,ATP2A2,ATP2A3,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CALY,CAMKK1,CREB1,CREBBP,CSNK1E,CSNK1G1,CSNK1G3,DRD2,DRD5,GNAQ,GNAS,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN3A,GUCY1A2,ITPR1,ITPR2,KCNJ10,KCNJ12,KCNJ14,KCNJ15,KCNJ3,KCNJ4,KCNJ5,KCNJ6,NOS1,PAWR,PLCB4,PLCE1,PLCG2,PLCL2,PPM1L,PPP1CA,PPP1R11,PPP1R14C,PPP1R3A,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKG1,PRKG2,PTPA"]
["Epithelial Adherens Junction Signaling",5.88,0.459,0.236,"ACTR3,ACVR1B,ACVR1C,ACVR2B,AFDN,AKT2,AKT3,ARHGAP35,ARHGEF17,ARPC4,ARPC5,BMPR2,CDC42,CDH1,CFL1,CFL2,CRK,CTNNA1,CTNNB1,EGF,EGFR,FER,FGF1,HGF,HNF1A,IGF1R,KRAS,LATS1,LATS2,LEF1,MAGI1,MYH10,MYH4,MYL12A,NANOS1,NOTCH1,PAK1,PAK3,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PTEN,PTPA,RAP1A,RAP2A,RAP2B,RAPGEF1,RHOA,RRAS2,SRC,STK11,STK3,TCF3,TCF7L2,TGFB2,TGFBR1,TNS1,VAV2,WWC1,YWHAB,YWHAG,YWHAH,ZBTB33"]
["Molecular Mechanisms of Cancer",5.85,0.383,{"$error":"#NUM!"},"ADCY1,ADCY2,ADCY3,ADCY5,AKT2,AKT3,APAF1,ARHGEF10,ARHGEF12,ARHGEF17,ARHGEF3,ARHGEF7,ATM,AXIN1,BAX,BCL2,BCL2L1,BMP2,BMP3,BMP5,BMP6,BMPR1A,BMPR1B,BMPR2,BRAF,BRCA1,CASP10,CBL,CCNE1,CCNE2,CDC25A,CDC42,CDH1,CDK10,CDK13,CDK14,CDK19,CDK2,CDK4,CDK8,CDK9,CDKN2A,CDKN2B,CHEK1,CREBBP,CRK,CTNNA1,CTNNB1,CYCS,DAXX,DIRAS3,E2F1,E2F2,E2F3,E2F6,FANCD2,FNBP1,FOXO1,FZD3,FZD5,FZD9,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GSK3B,HAT1,HDAC10,HDAC2,HDAC4,HDAC5,HDAC8,IRS1,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,JAK2,KRAS,LEF1,LRP1,LRP5,LRP6,MAP2K2,MAP2K4,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MAX,MDM2,NBN,NF1,NFKBIB,NFKBID,NLK,NOTCH1,PAK1,PAK3,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCB4,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKDC,PSEN1,PTCH1,PTK2,PTPN11,RAP1A,RAP2A,RAP2B,RAPGEF1,RAPGEF3,RASGRF1,RASGRF2,RBL1,RBPJ,RHOA,RHOB,RHOBTB2,RHOD,RHOJ,RHOQ,RHOT1,RHOT2,RRAS2,SHC3,SIN3A,SMAD2,SMAD4,SMAD5,SMAD6,SMAD9,SMO,SOS1,SRC,SUFU,SYNGAP1,TAB1,TAB2,TCF3,TGFB1,TGFB2,TGFB3,TGFBR1,TP53,WNT16,WNT2,WNT4,WNT7B,XIAP"]
["TGF-β Signaling",5.82,0.51,5.096,"ACVR1B,ACVR1C,ACVR2B,AMH,BCL2,BMP2,BMPR1A,BMPR1B,BMPR2,CDC42,CREBBP,FOXH1,GSC,HNF4A,HOXC9,INHA,KRAS,MAP2K2,MAP2K4,MAP4K1,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,NODAL,PIAS4,RAP1A,RAP2A,RAP2B,RRAS2,RUNX2,SKI,SMAD2,SMAD4,SMAD5,SMAD6,SMAD9,SMURF2,SOS1,TAB1,TFE3,TGFB1,TGFB2,TGFB3,TGFBR1,TLX2,VDR,ZFYVE9"]
["Protein Ubiquitination Pathway",5.74,0.411,{"$error":"#NUM!"},"AMFR,ANAPC1,ANAPC10,ANAPC5,BAG1,BRCA1,CBL,CDC23,CUL1,DNAJB11,DNAJB12,DNAJB6,DNAJB8,DNAJC10,DNAJC13,DNAJC14,DNAJC15,DNAJC16,DNAJC21,DNAJC22,DNAJC24,DNAJC5B,DNAJC7,DNAJC9,ELOB,ELOC,FBXW7,FZR1,HSP90AA1,HSPA13,HSPA14,HSPA1A/HSPA1B,HSPA4,HSPA4L,HSPA5,HSPA8,HSPA9,HSPB2,HSPB3,HSPB7,HSPB8,HSPD1,HSPE1,HSPH1,IFNG,MDM2,MED20,PAN2,PRKN,PSMA1,PSMA2,PSMA7,PSMB1,PSMC2,PSMD10,PSMD11,PSMD12,PSMD4,PSMD5,PSMD6,RPS27A,SACS,SKP1,SKP2,SMO,SMURF2,SUGT1,TRAP1,UBA1,UBA52,UBE2B,UBE2D1,UBE2D2,UBE2D3,UBE2E3,UBE2F,UBE2G1,UBE2H,UBE2I,UBE2J1,UBE2K,UBE2L3,UBE2V1,UBE2V2,UBE2W,UBE3A,UBE3B,UBE4B,USP1,USP12,USP13,USP15,USP19,USP2,USP25,USP3,USP30,USP31,USP32,USP33,USP34,USP36,USP39,USP4,USP42,USP45,USP46,USP49,USP53,USP7,USP9X,VHL,XIAP"]
["Regulation Of The Epithelial Mesenchymal Transition By Growth Factors Pathway",5.39,0.432,7.071,"AKT2,AKT3,BRAF,CDC42,CDH1,CHUK,EGF,EGFR,ERBB2,ESRP2,FGF1,FGF14,FGF18,FGF19,FGF20,FGF4,FGF5,FGF6,FGF7,FGF9,FGFR2,FGFR4,FGFRL1,FOXC2,FOXO1,FRS2,GSC,GSK3B,HGF,HMGA2,HSF1,IL6R,JAK2,KRAS,LATS1,LATS2,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MEST,MMP2,MTOR,OCLN,PARD6B,PARD6G,PDGFB,PDGFRA,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PTPN11,RAP1A,RAP2A,RAP2B,RHOA,RRAS2,SHC3,SMAD2,SMAD4,SOS1,TAB1,TCF3,TGFB1,TGFB2,TGFB3,TGFBR1,TNF,TNFSF10,TNFSF11,TNFSF13B,TNFSF8,TWIST1,WWTR1"]
["Oxytocin Signaling Pathway",5.38,0.405,9.313,"AKT2,AKT3,ARRB1,ATF2,ATF4,ATP2B2,ATP2B3,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CAMKK1,CD36,CREB1,CREBBP,EEF2,EGFR,GAD1,GNA12,GNAO1,GNAQ,GNB1L,GNB5,GNG10,GSK3B,GUCY1A2,GUCY2C,HSPB2,HSPB3,HSPB7,ITPR1,ITPR2,KCNT2,KRAS,LEP,LPL,MAP2K4,MAP2K5,MAPK1,MAPK12,MAPK14,MAPK15,MAPK4,MAPK8,MAPK9,MEF2C,MFN2,MPRIP,MYH10,MYH11,MYH14,MYH3,MYH4,MYH7,MYL1,MYL2,MYL6,MYL9,MYLK,NOS3,NPPA,NPR1,NPR2,NPR3,NT5C,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLA2G12A,PLA2G12B,PLA2G4C,PLCB4,PNPLA2,PPARA,PPARG,PPP1R12B,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKG1,PRKG2,RAP1A,RAP2A,RAP2B,RHOA,RRAS2,SHC3,SOS1,SOX15,TNFSF11"]
["Role of Osteoblasts, Osteoclasts and Chondrocytes in Rheumatoid Arthritis",5.34,0.42,{"$error":"#NUM!"},"ACP5,AKT2,AKT3,AXIN1,BCL2,BMP2,BMP3,BMP5,BMP6,BMPR1A,BMPR1B,BMPR2,CALCR,CALM1 (includes others),CBL,CHUK,COL1A1,CSNK1E,CSNK1G1,CSNK1G3,CTNNB1,DKK3,ELP1,FOXO1,FRZB,FZD3,FZD5,FZD9,GSK3B,GSN,HNF1A,IFNG,IL17A,IL18RAP,IL1A,IL1R1,IL1R2,IL1RAP,IL1RAPL2,IL1RL1,IL36A,IL37,IL7,ITGB3,LEF1,LRP1,LRP5,LRP6,MAP2K4,MAP2K7,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MMP13,MMP8,NFATC2,NFATC3,NFKBIB,NFKBID,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,RUNX2,SFRP2,SFRP4,SFRP5,SMAD4,SMAD5,SMAD6,SMAD9,SMO,SRC,TAB2,TCF3,TCF7L2,TGFB1,TNF,TNFSF11,WNT16,WNT2,WNT4,WNT7B,XIAP"]
["HER-2 Signaling in Breast Cancer",5.33,0.419,3.938,"AHCTF1,AKT1S1,AKT2,AKT3,ARF5,ARF6,BRAF,CCNE1,CCNE2,CDC42,CDK4,CHUK,COX10,COX11,COX15,COX5A,COX5B,COX6B1,COX7A1,COX7A2L,COX7B,COX7C,COX8C,DDX19B,EGF,EGFR,ELF3,ELF5,ERBB2,ERBB3,ETS2,FCER1A,FOXO1,GLE1,GNB1L,GSK3B,HBEGF,IL1A,ITGB1,ITGB2,ITGB3,ITGB8,KPNB1,KRAS,MAP2K2,MAPK1,MDM2,MMP2,MT-CO3,MTCL1,MTOR,NFKBIB,NFKBID,NRG1,NUP133,NUP153,NUP155,NUP160,NUP188,NUP205,NUP214,NUP35,NUP54,NUP58,NUP98,PARD3,PARD6B,PARD6G,PGR,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PRKCA,PRKCB,PRKCI,PRKD3,PTEN,RAP1A,RAP2A,RAP2B,RBL1,RHEB,RRAS2,SEH1L,SMAD4,SOS1,SRC,TP53,TP53RK,TSC1,XIAP"]
["Cardiac Hypertrophy Signaling (Enhanced)",5.29,0.367,11.811,"ACVR1B,ACVR1C,ACVR2B,ADCY1,ADCY2,ADCY3,ADCY5,ADRA1A,ADRA1D,ADRB2,AKAP13,AKT2,AKT3,ATF2,ATP2A1,ATP2A2,ATP2A3,BMPR2,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CHUK,CLCF1,CSF2RB,CTF1,CTNNB1,CYBB,DIAPH2,EDA,EDN1,EDNRA,EIF4E,EIF4EBP1,ENPP6,FGF1,FGF14,FGF18,FGF19,FGF20,FGF4,FGF5,FGF6,FGF7,FGF9,FGFR2,FGFR4,FGFRL1,FZD3,FZD5,FZD9,GATA4,GNA12,GNAQ,GNAS,GNB1L,GNB5,GNG10,GSK3B,HAND2,HDAC10,HDAC2,HDAC4,HDAC5,HDAC8,HSPB2,HSPB3,HSPB7,IFNG,IGF1R,IL12A,IL13,IL13RA2,IL17A,IL17RB,IL17RC,IL17RD,IL18RAP,IL1A,IL1R1,IL1R2,IL1RL1,IL25,IL2RB,IL31RA,IL36A,IL37,IL6R,IL7R,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,ITPR1,ITPR2,JAK2,KRAS,LEP,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAP3K13,MAP3K15,MAP3K20,MAP3K4,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MEF2A,MEF2C,MKNK2,MPPED2,MTOR,NAPEPLD,NFATC2,NFATC3,NPPA,NPR1,PDE10A,PDE11A,PDE12,PDE1A,PDE1C,PDE3B,PDE4A,PDE5A,PDE6A,PDE6H,PDE7A,PDE7B,PDE9A,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCB4,PLCE1,PLCG2,PLCL2,PLD6,PLN,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKG1,PTEN,PTK2,RAP1A,RAP2A,RAP2B,RHOA,RPS6KA5,RRAS2,RYR2,RYR3,SMO,SMPDL3A,SRF,TGFB1,TGFB2,TGFB3,TGFBR1,TNF,TNFSF10,TNFSF11,TNFSF13B,TNFSF8,TULP2,WNT16,WNT2,WNT4,WNT7B"]
["Pancreatic Adenocarcinoma Signaling",5.29,0.468,4.867,"AKT2,AKT3,BCL2,BCL2L1,BRCA2,CCNE1,CCNE2,CDC42,CDK2,CDK4,CDKN2A,CDKN2B,CYP2E1,E2F1,E2F2,E2F3,E2F6,EGF,EGFR,ERBB2,GPLD1,HBEGF,HDAC10,HDAC2,HDAC4,HDAC5,HDAC8,JAK2,KRAS,MAP2K2,MAP2K4,MAPK1,MAPK12,MAPK8,MAPK9,MDM2,NAPEPLD,NOTCH1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLD1,PLD4,PLD6,PROK1,RBL1,SIN3A,SMAD2,SMAD4,TGFB1,TGFB2,TGFB3,TGFBR1,TP53,VEGFA"]
["Autophagy",5.28,0.423,4.477,"AKT1S1,AKT2,AKT3,AMBRA1,ARL8B,ARNT,ATF2,ATF4,ATG10,ATG2B,ATG4B,ATG5,ATM,BCL2,BMP6,CALM1 (includes others),CREB1,CREBBP,E2F1,EGF,EIF2A,EPG5,ERN1,FOXO1,GCG,GNB1L,GORASP2,GSK3B,HGF,INSR,IRS1,IRS2,KAT5,LAMP1,LAMP2,MAP2K2,MAP2K4,MAP2K7,MAPK1,MAPK12,MAPK8,MAPK9,MTOR,PDGFB,PI4K2A,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAR1A,PRKAR2A,PTEN,PTPA,RAB7B,RAG1,RB1CC1,RIPK2,SLC1A5,SNAP29,SQSTM1,STK11,STX17,TGFB1,TGFB2,TNF,TP53,TRAF3,TSC1,VEGFA,WIPI2"]
["Adrenomedullin signaling pathway",5.25,0.427,8.152,"ADCY1,ADCY2,ADCY3,ADCY5,ADM,AKT2,AKT3,ARNT,BAX,BCL2,BRAF,CALM1 (includes others),CSK,GAD1,GNAQ,GNAS,GPR182,GSK3B,GUCY1A2,GUCY2C,IL1A,IL36A,IL37,ITPR1,ITPR2,KCNH2,KCNN1,KCNN3,KCNQ2,KRAS,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MAPK12,MAPK14,MAPK15,MAPK4,MAPK8,MAPK9,MATK,MAX,MMP2,MYLK,MYLK2,MYLK3,NOS3,NPR1,NPR2,NPR3,NT5C,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCB4,PLCE1,PLCG2,PLCL2,PPARG,PRKAG2,PRKAR1A,PRKAR2A,PRKG1,PRKG2,PTK2,RAP1A,RAP2A,RAP2B,RRAS2,RXRA,RXRG,SHC3,SHE,SHF,SOS1,SOX15,TFAP2A,TFAP2D,TNF,TTN"]
["ATM Signaling",5.23,0.495,1.206,"ATF1,ATF2,ATF4,ATM,BRCA1,CBX5,CDC25A,CDK2,CHEK1,CREB1,CREBBP,FANCD2,H2AX,H4C11,HERC2,KAT5,MAP2K4,MAPK12,MAPK14,MAPK8,MAPK9,MDM2,MDM4,MRE11,NBN,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PTPA,RAD17,RAD9A,RBBP8,RNF8,SMC1A,SMC1B,TDP1,TLK2,TP53,TP53BP1,TP73,TRIM28,TRRAP,USP7"]
["HIF1α Signaling",5.21,0.423,5.897,"ADM,AKT2,AKT3,ARNT,BMP6,BRAF,COPS5,CREBBP,CYBB,EDN1,EGF,EGLN1,EIF4E,EIF4EBP1,ELOB,ELOC,EPO,FLT1,FOXP3,GPI,HGF,HIF1AN,HSP90AA1,HSPA14,HSPA1A/HSPA1B,HSPA4,HSPA5,HSPA8,HSPA9,IGF2,IL17A,IL6R,KRAS,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MDM2,MKNK2,MMP12,MMP13,MMP19,MMP2,MMP21,MMP24,MMP27,MMP28,MMP8,MTOR,NAA10,NCF1,NCOA1,NOX1,PDGFB,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCG2,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKCA,PRKCB,PRKCI,PRKD3,PROK1,RACK1,RAN,RAP1A,RAP2A,RAP2B,RRAS2,SLC2A4,SLC2A5,SLC2A8,TF,TGFB1,TGFB2,TP53,VEGFA,VHL"]
["White Adipose Tissue Browning Pathway",5.06,0.456,6.565,"ADCY1,ADCY2,ADCY3,ADCY5,ANGPT2,ATF2,ATF4,BDNF,CACNA1D,CACNA1E,CACNA1F,CACNA1G,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CATSPER2,CREB1,CREBBP,CTBP2,DIO2,FCER1A,FGFR2,FGFR4,FGFRL1,FOXC2,GNAS,GUCY1A2,HIF1AN,HOXC9,ITPR1,ITPR2,KLB,LEP,MAPK1,MAPK12,MAPK14,NPPA,NPR1,PLIN1,PPARA,PPARG,PPARGC1A,PRDM16,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAR1A,PRKAR2A,PRKG1,PRKG2,RARG,RUNX1T1,RXRA,RXRG,SLC16A1,THRB,VEGFA"]
["AMPK Signaling",5.02,0.409,2.853,"ACACA,ACACB,ADRA1A,ADRA1D,ADRB2,AK1,AK2,AK3,AK5,AK8,AKT1S1,AKT2,AKT3,ARID2,ATF2,ATF4,BRD7,CHRM2,CHRM3,CHRM4,CHRNA3,CHRNA4,CHRNB2,CHRNG,CPT1C,CREB1,CREBBP,DPF1,EEF2,EEF2K,EIF4EBP1,ELAVL1,FOXO1,FOXO4,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GYS2,HMGCR,HNF4A,INSR,IRS1,IRS2,LEP,MAPK1,MAPK12,MAPK14,MTOR,NOS3,ORAI2,PBRM1,PFKFB1,PFKP,PHF10,PHLPP2,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPARGC1A,PPAT,PPM1A,PPM1B,PPM1E,PPM1F,PPM1G,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAR1A,PRKAR2A,PTPA,RAB11A,RAB2A,RAB39A,RAB3A,SLC2A4,SMARCA4,SMARCC1,STIM1,STK11,TBC1D1,TSC1"]
["Integrin Signaling",5,0.418,7.889,"ACTA2,ACTG2,ACTR3,AKT2,AKT3,ARF5,ARF6,ARHGEF7,ARPC4,ARPC5,ASAP1,BRAF,CAPN1,CAPN2,CAPN8,CAPN9,CAPNS1,CDC42,CRK,CRKL,CTTN,DIRAS3,DOCK1,FNBP1,GSK3B,GSN,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,KRAS,MAP2K2,MAP2K4,MAPK1,MAPK8,MPRIP,MYL12A,MYL2,MYL9,MYLK,MYLK2,MYLK3,NCK1,NCK2,NEDD9,PAK1,PAK3,PARVA,PARVB,PDGFB,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCG2,PPP1R12B,PTEN,PTK2,RAP1A,RAP2A,RAP2B,RAPGEF1,RHOA,RHOB,RHOBTB2,RHOD,RHOJ,RHOQ,RHOT1,RHOT2,RRAS2,SOS1,SRC,TLN1,TNK2,TSPAN5,TSPAN6,TTN,WASL,WIPF1,ZYX"]
["Cell Cycle: G1/S Checkpoint Regulation",4.9,0.529,-1.3,"ATM,BMI1,CCNE1,CCNE2,CDC25A,CDK2,CDK4,CDKN2A,CDKN2B,CUL1,E2F1,E2F2,E2F3,E2F6,FOXO1,GNL3,GSK3B,HDAC10,HDAC2,HDAC4,HDAC5,HDAC8,MAX,MDM2,NRG1,PAK1IP1,RBL1,RPL5,SIN3A,SKP1,SKP2,SMAD4,TGFB1,TGFB2,TGFB3,TP53"]
["Axonal Guidance Signaling",4.73,0.364,{"$error":"#NUM!"},"ABLIM1,ACTR3,ADAM11,ADAM12,ADAM15,ADAM22,ADAM28,ADAM29,ADAM30,ADAM32,ADAM33,ADAM8,ADAM9,ADAMTS12,ADAMTS13,ADAMTS17,ADAMTS19,ADAMTS8,ADAMTS9,AFG3L2,AKT2,AKT3,ARHGEF12,ARHGEF7,ARPC4,ARPC5,BDNF,BMP2,BMP3,BMP5,BMP6,CDC42,CFL1,CFL2,COPS5,CRK,CRKL,CXCR4,DCC,DOCK1,ECE2,EFNA5,EFNB1,EFNB3,EGF,EIF4E,EPHA10,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB6,ERBB2,FZD3,FZD5,FZD9,GDF7,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GSK3B,HERC2,HHIP,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,ITSN1,KALRN,KCNJ12,KLC1,KRAS,L1CAM,LINGO1,MAP2K2,MAPK1,MME,MMP12,MMP13,MMP2,MMP21,MMP24,MMP27,MMP28,MMP8,MYL1,MYL12A,MYL2,MYL6,MYL9,NCK1,NCK2,NFATC2,NFATC3,NRP1,NTRK2,NTRK3,PAK1,PAK3,PAPPA,PAPPA2,PDGFB,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PITRM1,PLCB4,PLCE1,PLCG2,PLCL2,PLXNA2,PLXNB1,PLXNB2,PLXNC1,PMPCA,PMPCB,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PROK1,PTCH1,PTK2,PTPN11,RAP1A,RAP2A,RAP2B,RGS3,RHOA,RHOD,ROBO3,RRAS2,SDC2,SEMA3D,SEMA3E,SEMA3F,SEMA4A,SEMA4C,SEMA4D,SEMA6A,SEMA6B,SEMA6D,SHANK2,SLIT1,SLIT2,SMO,SOS1,SRGAP2,SRGAP3,SUFU,UNC5A,UNC5C,UNC5D,VEGFA,WASL,WIPF1,WNT16,WNT2,WNT4,WNT7B,ZNF875"]
["Estrogen Receptor Signaling",4.7,0.374,8.785,"ADCY1,ADCY2,ADCY3,ADCY5,AKT2,AKT3,ATF2,ATF4,ATP5F1A,ATP5F1D,BCL2,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CARM1,CCNC,CDK8,CFL1,CFL2,CREB1,CREBBP,CTBP2,EGF,EGFR,EIF4E,EIF4EBP1,ESR1,FOXO1,FOXO4,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GSK3B,HNRNPD,HSP90AA1,IGF1R,IGF2,IGF2R,JAK2,KRAS,LEP,MAP2K2,MAPK1,MDK,MED1,MED13,MED13L,MED14,MED16,MED17,MED20,MED21,MED23,MED27,MED30,MED4,MMP12,MMP13,MMP19,MMP2,MMP21,MMP24,MMP27,MMP28,MMP8,MPRIP,MT-ATP6,MT-ND6,MTOR,MYL1,MYL12A,MYL2,MYL6,MYL9,NCOA1,NCOA2,NCOR1,NCOR2,NDUFA10,NDUFA11,NDUFA2,NDUFA7,NDUFA8,NDUFA9,NDUFB1,NDUFB6,NDUFS4,NDUFS8,NDUFV1,NOS3,NOTCH1,NRIP1,PAK1,PELP1,PGR,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCB4,PLCE1,PLCG2,PLCL2,PPARGC1A,PPP1R12B,PRKAA1,PRKAA2,PRKAB1,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKDC,PROK1,PTEN,RAP1A,RAP2A,RAP2B,RBFOX2,RHOA,RRAS2,RUNX2,SDHA,SETD7,SHC3,SHE,SHF,SOS1,SRC,TFAM,TP53,TRRAP,UQCRFS1,VEGFA,ZDHHC21"]
["HIPPO signaling",4.64,0.494,-3.138,"AJUBA,CRB1,CSNK1E,CUL1,DLG2,DLG3,FAT4,ITCH,LATS1,LATS2,LLGL1,PARD3,PATJ,PPM1L,PPP1CA,PPP1R11,PPP1R14C,PPP1R3A,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PTPA,SAV1,SKP1,SKP2,SMAD2,SMAD4,SMAD5,STK3,TEAD2,TEAD3,TEAD4,TJP2,WWC1,WWTR1,YWHAB,YWHAG,YWHAH"]
["Prostate Cancer Signaling",4.62,0.464,{"$error":"#NUM!"},"AKT2,AKT3,AR,ATF2,ATF4,BCL2,CCNE1,CCNE2,CDK2,CHUK,CREB1,CREBBP,CTNNB1,E2F1,E2F2,E2F3,E2F6,FOXO1,GSK3B,GSTP1,HDAC10,HDAC2,HDAC4,HDAC5,HDAC8,HSP90AA1,KRAS,LEF1,MAP2K2,MAPK1,MDM2,MTOR,NFKBIB,NFKBID,NKX3-1,PDPK1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PTEN,RAP1A,RAP2A,RAP2B,RBL1,RRAS2,SIN3A,SOS1,TP53"]
["Role of CHK Proteins in Cell Cycle Checkpoint Control",4.61,0.544,2.858,"ATM,BRCA1,CDC25A,CDK2,CHEK1,CLSPN,E2F1,E2F2,E2F3,E2F6,HUS1,MRE11,NBN,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PTPA,RAD1,RAD17,RAD9A,RFC3,RFC4,RFC5,SLC19A1,TLK2,TP53"]
["Reelin Signaling in Neurons",4.58,0.452,6.379,"ACTR3,AFDN,AKT2,AKT3,APOE,ARHGEF10,ARHGEF12,ARHGEF3,ARPC4,ARPC5,CDC42,CDK5R1,CFL1,CNR1,CRK,CRKL,DAB1,DCX,DNAH1,DNAH10,DNAH3,DNALI1,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN3A,GSK3B,ITGB1,LRP8,MAP1B,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAP4K1,MAPK1,MAPK12,MAPK8,MAPK9,MTOR,PAFAH1B1,PDK2,PDK3,PDK4,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,RAP1A,RAPGEF1,RHOA,SRC,WASL"]
["Colorectal Cancer Metastasis Signaling",4.57,0.395,7.548,"ADCY1,ADCY2,ADCY3,ADCY5,AKT2,AKT3,APPL1,ARRB1,AXIN1,BAX,BCL2L1,BRAF,CDC42,CDH1,CTNNB1,DCC,DIRAS3,EGF,EGFR,FNBP1,FZD3,FZD5,FZD9,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GRK2,GRK3,GSK3B,HNF1A,IFNG,IL6R,JAK2,KRAS,LEF1,LRP1,LRP5,LRP6,MAP2K2,MAP2K4,MAPK1,MAPK12,MAPK8,MAPK9,MMP12,MMP13,MMP19,MMP2,MMP21,MMP24,MMP27,MMP28,MMP8,MSH2,MSH6,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PRKAG2,PRKAR1A,PRKAR2A,PROK1,PTGER2,PTGER3,PTGER4,RAP1A,RAP2A,RAP2B,RHOA,RHOB,RHOBTB2,RHOD,RHOJ,RHOQ,RHOT1,RHOT2,RRAS2,SIAH1,SMAD2,SMAD4,SMO,SOS1,SRC,TCF3,TCF7L2,TGFB1,TGFB2,TGFB3,TGFBR1,TLR2,TLR7,TLR8,TNF,TP53,VEGFA,WNT16,WNT2,WNT4,WNT7B"]
["Opioid Signaling Pathway",4.49,0.392,5.787,"ADCY1,ADCY2,ADCY3,ADCY5,AKT2,AKT3,AP2A1,AP2S1,ARRB1,ATF2,ATF4,BRAF,CACNA1D,CACNA1E,CACNA1F,CACNA1G,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),CATSPER2,CDC42,CLTA,CLTC,CREB1,CREBBP,CTNNB1,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN3A,GRK2,GRK3,GRK5,GRK6,GRK7,GSK3B,HNF1A,ITPR1,ITPR2,KCNJ3,KCNJ5,KCNJ6,KRAS,LEF1,MAP2K2,MAP2K4,MAP2K5,MAP2K7,MAPK1,MAPK12,MAPK15,MAPK4,NOS1,NOS3,OPRD1,OPRL1,PDE1A,PDE1C,PENK,PIK3C2G,PIK3CG,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,RAP1A,RAP2A,RAP2B,RGS10,RGS13,RGS14,RGS16,RGS3,RGS4,RGS5,RGS6,RGS7,RPS6KA5,RPS6KA6,RRAS2,RYR2,RYR3,SCN7A,SOS1,SRC,SRF,TCF3,TCF7L2"]
["Ephrin Receptor Signaling",4.49,0.413,7.091,"ACTR3,AKT2,AKT3,ARPC4,ARPC5,ATF2,ATF4,AXIN1,CDC42,CFL1,CFL2,CREB1,CREBBP,CRK,CRKL,CXCR4,EFNA5,EFNB1,EFNB3,EGF,EPHA10,EPHA5,EPHA6,EPHA7,EPHA8,EPHB1,EPHB2,EPHB3,EPHB6,FGF1,GNA12,GNAO1,GNAQ,GNAS,GNB1L,GNB5,GNG10,GRIN1,GRIN2A,GRIN2B,GRIN2C,GRIN3A,ITGA11,ITGA4,ITGA8,ITGA9,ITGAL,ITGB1,ITGB2,ITGB3,ITGB8,ITSN1,JAK2,KALRN,KRAS,MAP2K2,MAPK1,NCK1,NCK2,PAK1,PAK3,PDGFB,PIK3C2G,PIK3CG,PROK1,PTK2,PTPN11,PTPN13,RAP1A,RAP2A,RAP2B,RAPGEF1,RGS3,RHOA,RRAS2,SDC2,SH2D3C,SORBS1,SOS1,SRC,VEGFA,WASL,WIPF1"]
["RAR Activation",4.48,0.412,{"$error":"#NUM!"},"ADCY1,ADCY2,ADCY3,ADCY5,ADH1B,ADH1C,ADH4,ADH7,AKR1C1/AKR1C2,AKT2,AKT3,ALDH1A1,ALDH1A3,ARID2,BRD7,CARM1,CCNH,CITED2,CREBBP,CSF2RB,CSK,CSNK2A2,DPF1,GTF2H2,GTF2H5,JAK2,MAP2K4,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MED1,MNAT1,NCOA1,NCOR1,NCOR2,NR2F1,NR2F2,NR2F6,NRIP1,NSD1,PBRM1,PDPK1,PHF10,PIK3CG,PIK3R2,PNPLA4,PPARGC1A,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRMT1,PTEN,RARG,RBP7,RDH13,RPL7A,RXRA,RXRG,SCAND1,SDR9C7,SMAD2,SMAD4,SMAD5,SMAD6,SMAD9,SMARCA4,SMARCC1,SNW1,SORBS3,SRC,STAT5B,TGFB1,TGFB2,TGFB3,TNIP1,TRIM24,VEGFA,ZBTB16"]
["Tight Junction Signaling",4.47,0.421,{"$error":"#NUM!"},"ACTA2,ACTG2,AFDN,AKT2,AKT3,CASK,CDC42,CDK4,CLDN1,CLDN11,CLDN19,CLDN23,CLDN4,CLDN6,CLDN8,CLDN9,CNKSR3,CPSF1,CPSF6,CSTF1,CSTF2,CTNNA1,CTNNB1,EPB41,F11R,F2RL2,GOSR2,GPAA1,HSF1,JAM3,LLGL1,MARK2,MPDZ,MYH10,MYH11,MYH14,MYH3,MYH4,MYH7,MYL1,MYL2,MYL6,MYL9,MYLK,NAPB,NSF,NUDT21,OCLN,PATJ,PPM1L,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PRKAG2,PRKAR1A,PRKAR2A,PRKCI,PTEN,PTPA,RHOA,SAFB,STX4,TGFB1,TGFB2,TGFB3,TGFBR1,TJP1,TJP2,TNF,VAPA,VTI1A"]
["Protein Kinase A Signaling",4.44,0.371,2.455,"ADCY1,ADCY2,ADCY3,ADCY5,ADD2,ADD3,AKAP11,AKAP12,AKAP13,AKAP17A,AKAP8,AKAP9,ANAPC1,ANAPC10,ANAPC5,ATF1,ATF2,ATF4,BRAF,CALM1 (includes others),CDC14B,CDC23,CDC25A,CHUK,CNGB1,CREB1,CREBBP,CTNNB1,DCC,DUSP15,DUSP16,DUSP5,DUSP7,ENPP6,EYA2,EYA3,GNAQ,GNAS,GNB1L,GNB5,GNG10,GRK7,GSK3B,GYS2,H1-1,H1-6,H3-3A/H3-3B,HNF1A,ITPR1,ITPR2,LEF1,MAP2K2,MAPK1,MPPED2,MTMR3,MYH10,MYH4,MYL1,MYL12A,MYL2,MYL6,MYL9,MYLK,MYLK2,MYLK3,NAPEPLD,NFATC2,NFATC3,NFKBIB,NFKBID,NOS3,PALM2AKAP2,PDE10A,PDE11A,PDE12,PDE1A,PDE1C,PDE3B,PDE4A,PDE5A,PDE6A,PDE6H,PDE7A,PDE7B,PDE9A,PGP,PHKA2,PHKB,PLCB4,PLCE1,PLCG2,PLCL2,PLD6,PLN,PPP1CA,PPP1R11,PPP1R14C,PPP1R3A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PTCH1,PTEN,PTK2,PTP4A1,PTPN11,PTPN13,PTPN14,PTPN18,PTPN2,PTPN22,PTPN3,PTPN7,PTPN9,PTPRC,PTPRD,PTPRF,PTPRG,PTPRS,PYGL,RAP1A,RHO,RHOA,RYR2,RYR3,SIRPA,SMAD4,SMO,SMPDL3A,TCF3,TCF7L2,TGFB1,TGFB2,TGFB3,TGFBR1,TIMM50,TNNI3,TTN,TULP2,YWHAB,YWHAG,YWHAH"]
["Superpathway of Inositol Phosphate Compounds",4.43,0.402,8.775,"ACP5,ATP1A1,CDC25A,DOT1L,DUSP13,DUSP14,DUSP15,DUSP16,DUSP23,DUSP5,EPHX2,EYA4,G6PC3,IGBP1,INPP5A,INPP5B,INPP5K,IP6K2,IP6K3,IPMK,IPPK,ITPK1,ITPKA,ITPKB,MTMR4,MTMR8,NT5C,NUDT12,NUDT16,NUDT2,NUDT3,NUDT4,PALD1,PAWR,PI4K2A,PI4KA,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PIP5K1A,PLCB4,PLCE1,PLCG2,PPFIA1,PPFIA3,PPIP5K1,PPIP5K2,PPM1L,PPP1CA,PPP1R11,PPP1R12B,PPP1R14C,PPP1R1A,PPP1R3A,PPP2CA,PPP2R1A,PPP2R1B,PPP2R2A,PPP2R3A,PPP2R3B,PPP2R5A,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PPP4C,PPP5C,PPTC7,PTEN,PTPA,PTPN11,PTPN13,PTPN2,PTPN22,PTPN7,PTPRC,PTPRF,PXYLP1,RNGTT,SACM1L,SET,SGPP2,SIRPA,SSH1,SSH2,STYXL1,SYNJ1,SYNJ2,TPTE"]
["Nitric Oxide Signaling in the Cardiovascular System",4.42,0.454,5.246,"AKT2,AKT3,ATP2A1,ATP2A2,ATP2A3,CACNA1D,CACNA1E,CACNA1F,CACNB2,CACNB4,CACNG1,CACNG2,CACNG4,CACNG7,CACNG8,CALM1 (includes others),FLT1,GUCY1A2,GUCY2C,HSP90AA1,ITPR1,ITPR2,KNG1,MAP2K2,MAPK1,NOS3,NPR1,NPR2,PDE1A,PDE1C,PDE3B,PDE5A,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLN,PRKAA1,PRKAG2,PRKAR1A,PRKAR2A,PRKCA,PRKCB,PRKCI,PRKD3,PRKG1,PRKG2,PROK1,RYR2,SLC7A1,VEGFA"]
["Leukocyte Extravasation Signaling",4.42,0.415,6.231,"ACTA2,ACTG2,AFDN,ARHGAP35,ARHGAP4,ARHGAP6,ARHGAP9,CDC42,CLDN1,CLDN11,CLDN19,CLDN23,CLDN4,CLDN6,CLDN8,CLDN9,CRK,CRKL,CTNNA1,CTNNB1,CTTN,CXCR4,CYBA,CYBB,DLC1,EDIL3,F11R,FER,ITGA4,ITGAL,ITGB1,ITGB2,JAM3,MAP2K2,MAP2K4,MAP3K4,MAPK1,MAPK12,MAPK14,MAPK8,MAPK9,MMP12,MMP13,MMP19,MMP2,MMP21,MMP24,MMP27,MMP28,MMP8,MSN,MYL6,NCF1,NOX1,PECAM1,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PLCG2,PRKCA,PRKCB,PRKCI,PRKD3,PTK2,PTPN11,RAP1A,RAPGEF3,RDX,RHOA,SPN,SRC,THY1,TIMP4,VAV2,WASL,WIPF1"]
["Clathrin-mediated Endocytosis Signaling",4.42,0.415,{"$error":"#NUM!"},"AAK1,ACTA2,ACTG2,ACTR3,ALB,AP1G1,AP1M2,AP1S2,AP2A1,AP2S1,APOC1,APOC4,APOE,ARF6,ARPC4,ARPC5,ARRB1,CBL,CD2AP,CDC42,CLTA,CLTC,CLU,CSNK2A2,CTTN,DAB2,DNM1,EGF,EPHB2,EPN1,FGF1,FGF14,FGF18,FGF19,FGF20,FGF4,FGF5,FGF6,FGF7,FGF9,HIP1,HIP1R,HSPA8,ITGB1,ITGB2,ITGB3,ITGB8,MDM2,ORM1,PDGFB,PIK3C2A,PIK3C2G,PIK3C3,PIK3CG,PIK3R2,PIK3R4,PIK3R5,PPP3CA,PPP3CB,PPP3CC,PPP3R1,PPP3R2,PROK1,RAB11A,RAB11B,RAB4A,RAB4B,RAB5C,RPS27A,S100A8,SH3GLB2,SRC,STON2,SYNJ1,TF,TFRC,UBA52,USP9X,VEGFA,WASL"]