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[]
[null,null,"Supplemantary. Table-1: List and main properties of the pathway genes used as reference sequence in the study.","Supplemantary. Table: List and main properties of the genes used as reference sequence in the study."]
[]
[null,null,"Pathway","Gene No","Gene Symbol","Gene Stable ID","Chromosomal Location (Karyotype Band)","Coordinate                                           (GRCh37/hg19)","Strand","Transcript Count","Sequence Length                     (base pair)","GC Content (%)"]
[null,null,"mTOR",1,"AKT1","ENSG00000142208","14q32.33","Chr14:104769349-104795751",-1,19,26402,"64.08"]
[{"$nulls":3},2,"EIF4E","ENSG00000151247","4q23","Chr4:98879276-98929133",-1,11,58953,"39.01"]
[{"$nulls":3},3,"EIF4EBP1","ENSG00000187840","8p11.23","Chr8:38030534-38060365",1,2,30024,"49.17"]
[{"$nulls":3},4,"FKBP1A","ENSG00000088832","20p13","Chr20:1368977-1393164",-1,19,24184,"45.46"]
[{"$nulls":3},5,"FOXO3","ENSG00000118689","6q21","Chr6:108559835-108684774",1,3,124939,"41.71"]
[{"$nulls":3},6,"GSK3B","ENSG00000082701","3q13.33","Chr3:119821321-120094994",-1,69,273094,"37.20"]
[{"$nulls":3},7,"LAMTOR1","ENSG00000149357","11q13.4","Chr11:72085895-72103297",-1,8,17492,"47.92"]
[{"$nulls":3},8,"LAMTOR2","ENSG00000116586","1q22","Chr1:156054782-156058506",1,6,3758,"50.95"]
[{"$nulls":3},9,"LAMTOR3","ENSG00000109270","4q23","Chr4:99878336-99894428",-1,3,16154,"34.87"]
[{"$nulls":3},10,"LAMTOR4","ENSG00000188186","7q22.1","Chr7:100148907-100155944",1,12,7037,"53.24"]
[{"$nulls":3},11,"LAMTOR5","ENSG00000134248","1p13.3","Chr1:110401249-110407942",-1,7,6693,"42.55"]
[{"$nulls":3},12,"MAPKAP1","ENSG00000119487","9q33.3","Chr9:125437393-125707234",-1,20,269841,"41.82"]
[{"$nulls":3},13,"MLST8","ENSG00000167965","16p13.3","Chr16:2204248-2209453",1,35,5168,"61.93"]
[{"$nulls":3},14,"MTOR","ENSG00000198793","1p36.22","Chr1:11106535-11262551",-1,7,155972,"44.54"]
[{"$nulls":3},15,"NOS3","ENSG00000164867","7q36.1","Chr7:150991017-151014588",1,10,23593,"57.59"]
[{"$nulls":3},16,"PDPK1","ENSG00000140992","16p13.3","Chr16:2537979-2603188",1,17,65224,"52.50"]
[{"$nulls":3},17,"PIK3CA","ENSG00000121879","3q26.32","Chr3:179148114-179240093",1,10,91979,"35.78"]
[{"$nulls":3},18,"PPP2CA","ENSG00000113575","5q31.1","Chr5:134194332-134226073",-1,6,31808,"40.30"]
[{"$nulls":3},19,"RHEB","ENSG00000106615","7q36.1","Chr7:151466012-151520120",-1,7,54108,"42.00"]
[{"$nulls":3},20,"RICTOR","ENSG00000164327","5p13.1","Chr5:38937920-39074399",-1,10,136489,"35.53"]
[{"$nulls":3},21,"RPS6","ENSG00000137154","9p22.1","Chr9:19375715-19380236",-1,5,4539,"40.65"]
[{"$nulls":3},22,"RPS6KB1","ENSG00000108443","17q23.1","Chr17:59893046-59950574",1,12,57478,"41.68"]
[{"$nulls":3},23,"RPTOR","ENSG00000141564","17q25.3","Chr17:80544819-80966371",1,12,421552,"49.12"]
[{"$nulls":3},24,"RRAGA","ENSG00000155876","9p22.1","Chr9:19049427-19051025",1,1,1647,"51.09"]
[{"$nulls":3},25,"RRAGB","ENSG00000083750","Xp11.21","ChrX:55717749-55758774",1,6,41035,"40.86"]
[{"$nulls":3},26,"RRAGC","ENSG00000116954","1p34.3","Chr1:38838198-38859772",-1,4,21625,"41.36"]
[{"$nulls":3},27,"RRAGD","ENSG00000025039","6q15","Chr6:89364616-89412273",-1,3,47634,"42.23"]
[{"$nulls":3},28,"SLC38A9","ENSG00000177058","5q11.2","Chr5:55625845-55773194",-1,26,147349,"38.77"]
[{"$nulls":3},29,"TGFBR1","ENSG00000106799","9q22.33","Chr9:99104038-99154192",1,10,50154,"39.03"]
[{"$nulls":3},30,"TSC1","ENSG00000165699","9q34.13","Chr9:132891348-132946874",-1,47,53285,"43.24"]
[{"$nulls":3},31,"TSC2","ENSG00000103197","16p13.3","Chr16:2047967-2089491",1,69,41250,"59.93"]
[null,null,"TGF-beta",1,"ACVR1","ENSG00000115170","2q24.1","Chr2:158592958-158732374",-1,10,139416,"40.31"]
[{"$nulls":3},2,"ACVR1B","ENSG00000135503","12q13.13","Chr12:52345451-52390862",1,7,45411,"44.84"]
[{"$nulls":3},3,"ACVR1C","ENSG00000123612","2q24.1","Chr2:158383279-158485517",-1,4,102238,"36.88"]
[{"$nulls":3},4,"ACVR2A","ENSG00000121989","2q22.3","Chr2:148602086-148688393",1,7,86307,"35.46"]
[{"$nulls":3},5,"ACVR2B","ENSG00000114739","3p22.2","Chr3:38495342-38534633",1,3,39291,"47.64"]
[{"$nulls":3},6,"AMH","ENSG00000104899","19p13.3","Chr19:2249308-2252072",1,4,2764,"71.68"]
[{"$nulls":3},7,"AMHR2","ENSG00000135409","12q13.13","Chr12:53817639-53825318",1,7,7679,"52.75"]
[{"$nulls":3},8,"BAMBI","ENSG00000095739","10p12.1","Chr10:28966271-28971868",1,2,5597,"47.11"]
[{"$nulls":3},9,"BMP2","ENSG00000125845","20p12.3","Chr20:6748311-6760927",1,1,12616,"43.78"]
[{"$nulls":3},10,"BMP4","ENSG00000125378","14q22.2","Chr14:54416454-54425479",-1,9,9025,"53.91"]
[{"$nulls":3},11,"BMP5","ENSG00000112175","6p12.1","Chr6:55618443-55740362",-1,2,121919,"34.10"]
[{"$nulls":3},12,"BMP6","ENSG00000153162","6p24.3","Chr6:7727030-7881655",1,1,154625,"43.38"]
[{"$nulls":3},13,"BMP7","ENSG00000101144","20q13.31","Chr20:55743804-55841685",-1,9,97881,"49.98"]
[{"$nulls":3},14,"BMP8A","ENSG00000183682","1p34.3","Chr1:39957318-39991607",1,1,34289,"55.00"]
[{"$nulls":3},15,"BMP8B","ENSG00000116985","1p34.2","Chr1:40222854-40254533",-1,2,31679,"55.56"]
[{"$nulls":3},16,"BMPR1A","ENSG00000107779","10q23.2","Chr10:88516407-88692595",1,2,176188,"39.89"]
[{"$nulls":3},17,"BMPR1B","ENSG00000138696","4q22.3","Chr4:95679119-96079599",1,8,400480,"36.70"]
[{"$nulls":3},18,"BMPR2","ENSG00000204217","2q33.1","Chr2:203241659-203432474",1,3,190815,"41.04"]
[{"$nulls":3},19,"CDKN2B","ENSG00000147883","9p21.3","Chr9:22002902-22009362",-1,4,6460,"41.28"]
[{"$nulls":3},20,"CHRD","ENSG00000090539","3q27.1","Chr3:184097861-184108524",1,19,10663,"59.37"]
[{"$nulls":3},21,"CREBBP","ENSG00000005339","16p13.3","Chr16:3775055-3930727",-1,12,155672,"45.01"]
[{"$nulls":3},22,"CUL1","ENSG00000055130","7q36.1","Chr7:148395006-148498128",1,3,103122,"41.22"]
[{"$nulls":3},23,"DCN","ENSG00000011465","12q21.33","Chr12:91539025-91576900",-1,22,37875,"34.59"]
[{"$nulls":3},24,"E2F4","ENSG00000205250","16q22.1","Chr16:67226072-67232821",1,13,6749,"56.55"]
[{"$nulls":3},25,"E2F5","ENSG00000133740","8q21.2","Chr8:86089460-86129387",1,9,39927,"39.49"]
[{"$nulls":3},26,"EP300","ENSG00000100393","22q13.2","Chr22:41487790-41576081",1,1,88291,"42.33"]
[{"$nulls":3},27,"FBN1","ENSG00000166147","15q21.1","Chr15:48700503-48938046",-1,8,237543,"38.92"]
[{"$nulls":3},28,"FMOD","ENSG00000122176","1q32.1","Chr1:203309756-203320617",-1,3,10861,"50.17"]
[{"$nulls":3},29,"FST","ENSG00000134363","5q11.2","Chr5:52776239-52782964",1,5,6725,"45.51"]
[{"$nulls":3},30,"GDF5","ENSG00000125965","20q11.22","Chr20:34021145-34042568",-1,2,21423,"48.35"]
[{"$nulls":3},31,"GDF6","ENSG00000156466","8q22.1","Chr8:97154562-97173020",-1,1,18458,"51.71"]
[{"$nulls":3},32,"GDF7","ENSG00000143869","2p24.1","Chr2:20866424-20873418",1,1,6994,"59.51"]
[{"$nulls":3},33,"GREM1","ENSG00000166923","15q13.3","Chr15:33010175-33026870",1,4,16695,"43.51"]
[{"$nulls":3},34,"GREM2","ENSG00000180875","1q43","Chr1:240652873-240775449",-1,1,122576,"40.58"]
[{"$nulls":3},35,"HAMP","ENSG00000105697","19q13.12","Chr19:35771619-35776046",1,3,4427,"54.11"]
[{"$nulls":3},36,"ID1","ENSG00000125968","20q11.21","Chr20:30193086-30194318",1,2,1232,"58.56"]
[{"$nulls":3},37,"ID2","ENSG00000115738","2p25.1","Chr2:8818975-8824583",1,4,5608,"49.26"]
[{"$nulls":3},38,"ID3","ENSG00000117318","1p36.12","Chr1:23884409-23886285",-1,3,1876,"57.27"]
[{"$nulls":3},39,"ID4","ENSG00000172201","6p22.3","Chr6:19837617-19840915",1,1,3298,"53.08"]
[{"$nulls":3},40,"IFNG","ENSG00000111537","12q15","Chr12:68548548-68553527",-1,1,4979,"36.04"]
[{"$nulls":3},41,"INHBA","ENSG00000122641","7p14.1","Chr7:41724712-41742706",-1,3,17994,"41.68"]
[{"$nulls":3},42,"INHBB","ENSG00000163083","2q14.2","Chr2:121103719-121109384",1,1,5665,"56.09"]
[{"$nulls":3},43,"INHBC","ENSG00000175189","12q13.3","Chr12:57828543-57844611",1,1,16068,"46.80"]
[{"$nulls":3},44,"INHBE","ENSG00000139269","12q13.3","Chr12:57846106-57853063",1,4,6957,"53.48"]
[{"$nulls":3},45,"LEFTY1","ENSG00000243709","1q42.12","Chr1:226073982-226099082",-1,2,25100,"50.49"]
[{"$nulls":3},46,"LEFTY2","ENSG00000143768","1q42.12","Chr1:226124298-226129189",-1,3,4891,"56.28"]
[{"$nulls":3},47,"LTBP1","ENSG00000049323","2p22.3","Chr2:33172039-33624576",1,15,452537,"40.25"]
[{"$nulls":3},48,"MAPK1","ENSG00000100030","22q11.22","Chr22:22108789-22221970",-1,4,113181,"43.80"]
[{"$nulls":3},49,"MAPK3","ENSG00000102882","16p11.2","Chr16:30125426-30134827",-1,16,9401,"56.36"]
[{"$nulls":3},50,"MYC","ENSG00000136997","8q24.21","Chr8:128747680-128753674",1,5,5994,"53.81"]
[{"$nulls":3},51,"NBL1","ENSG00000158747","1p36.13","Chr1:19967048-19984945",1,9,17897,"56.98"]
[{"$nulls":3},52,"NEO1","ENSG00000067141","15q24.1","Chr15:73344051-73597547",1,11,253496,"38.73"]
[{"$nulls":3},53,"NODAL","ENSG00000156574","10q22.1","Chr10:72192071-72207707",-1,2,15636,"51.26"]
[{"$nulls":3},54,"NOG","ENSG00000183691","17q22","Chr17:54671060-54672951",1,1,1891,"59.46"]
[{"$nulls":3},55,"PITX2","ENSG00000164093","4q25","Chr4:111538579-111563279",-1,10,24700,"49.37"]
[{"$nulls":3},56,"PPP2CA","ENSG00000113575","5q31.1","Chr5:133530025-133561833",-1,6,31808,"40.38"]
[{"$nulls":3},57,"PPP2CB","ENSG00000104695","8p12","Chr8:30631973-30671830",-1,10,39857,"41.95"]
[{"$nulls":3},58,"PPP2R1A","ENSG00000105568","19q13.41","Chr19:52693292-52730687",1,12,37395,"48.26"]
[{"$nulls":3},59,"PPP2R1B","ENSG00000137713","11q23.1","Chr11:111597632-111637151",-1,13,39519,"44.57"]
[{"$nulls":3},60,"RBL1","ENSG00000080839","20q11.23","Chr20:35624752-35724398",-1,4,99646,"43.07"]
[{"$nulls":3},61,"RBL1","ENSG00000269846","20q11.23","Chr20:35724188-35725581",1,1,1393,"55.52"]
[{"$nulls":3},62,"RBX1","ENSG00000100387","22q13.2","Chr22:41347351-41369313",1,3,21962,"44.92"]
[{"$nulls":3},63,"RGMA","ENSG00000182175","15q26.1","Chr15:93586636-93632433",-1,14,45797,"52.74"]
[{"$nulls":3},64,"RGMB","ENSG00000174136","5q15","Chr5:98104354-98134347",1,7,29993,"43.29"]
[{"$nulls":3},65,"RHOA","ENSG00000067560","3p21.31","Chr3:49396578-49450431",-1,6,53853,"46.57"]
[{"$nulls":3},66,"ROCK1","ENSG00000067900","18q11.1","Chr18:18526867-18691812",-1,6,164945,"36.92"]
[{"$nulls":3},67,"RPS6KB1","ENSG00000108443","17q23.1","Chr17:57970447-58027925",1,12,57478,"41.67"]
[{"$nulls":3},68,"RPS6KB2","ENSG00000175634","11q13.2","Chr11:67195931-67202872",1,13,6941,"58.79"]
[{"$nulls":3},69,"SKP1","ENSG00000113558","5q31.1","Chr5:133484633-133512729",-1,13,28096,"41.25"]
[{"$nulls":3},70,"SMAD1","ENSG00000170365","4q31.21","Chr4:146402346-146479231",1,16,76885,"38.45"]
[{"$nulls":3},71,"SMAD2","ENSG00000175387","18q21.1","Chr18:45357922-45457515",-1,12,99593,"36.57"]
[{"$nulls":3},72,"SMAD3","ENSG00000166949","15q22.33","Chr15:67356101-67487533",1,15,131432,"48.34"]
[{"$nulls":3},73,"SMAD4","ENSG00000141646","18q21.2","Chr18:48494410-48611415",1,17,117005,"40.04"]
[{"$nulls":3},74,"SMAD5","ENSG00000113658","5q31.1","Chr5:135468534-135524435",1,13,55901,"37.17"]
[{"$nulls":3},75,"SMAD6","ENSG00000137834","15q22.31","Chr15:66994566-67074338",1,6,79772,"50.92"]
[{"$nulls":3},76,"SMAD7","ENSG00000101665","18q21.1","Chr18:46446223-46477081",-1,8,30858,"52.06"]
[{"$nulls":3},77,"SMAD9","ENSG00000120693","13q13.3","Chr13:37418968-37494902",-1,4,75934,"41.07"]
[{"$nulls":3},78,"SMURF1","ENSG00000198742","7q22.1","Chr7:98625061-98741723",-1,4,116662,"42.72"]
[{"$nulls":3},79,"SMURF2","ENSG00000108854","17q24.1","Chr17:62538413-62658186",-1,7,119773,"39.40"]
[{"$nulls":3},80,"SP1","ENSG00000185591","12q13.13","Chr12:53773960-53810230",1,4,36270,"45.65"]
[{"$nulls":3},81,"TFDP1","ENSG00000198176","13q34","Chr13:114239013-114295785",1,9,56772,"53.35"]
[{"$nulls":3},82,"TGFB1","ENSG00000105329","19q13.2","Chr19:41807492-41859816",-1,4,52324,"53.13"]
[{"$nulls":3},83,"TGFB2","ENSG00000092969","1q41","Chr1:218519577-218617961",1,4,98384,"41.85"]
[{"$nulls":3},84,"TGFB3","ENSG00000119699","14q24.3","Chr14:76424442-76449334",-1,7,24892,"48.99"]
[{"$nulls":3},85,"TGFBR1","ENSG00000106799","9q22.33","Chr9:101866320-101916474",1,10,50154,"39.03"]
[{"$nulls":3},86,"TGFBR2","ENSG00000163513","3p24.1","Chr3:30647994-30735634",1,2,87640,"40.81"]
[{"$nulls":3},87,"TGIF1","ENSG00000177426","18p11.31","Chr18:3411606-3458409",1,22,46803,"44.07"]
[{"$nulls":3},88,"TGIF2","ENSG00000118707","20q11.23","Chr20:35201891-35222353",1,7,20462,"51.95"]
[{"$nulls":3},89,"THBS1","ENSG00000137801","15q14","Chr15:39873280-39891667",1,9,18387,"43.51"]
[{"$nulls":3},90,"THSD4","ENSG00000187720","15q23","Chr15:71389291-72075722",1,6,686431,"42.50"]
[{"$nulls":3},91,"TNF","ENSG00000232810","6p21.33","Chr6:31543344-31546113",1,1,2769,"52.82"]
[{"$nulls":3},92,"ZFYVE16","ENSG00000039319","5q14.1","Chr5:79703832-79775169",1,13,71337,"37.65"]
[{"$nulls":3},93,"ZFYVE9","ENSG00000157077","1p32.3","Chr1:52608046-52812358",1,5,204312,"40.79"]