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{"sheet":"Sayfa1","index":0,"n_rows":14,"n_cols":6,"rows_kept":14,"merged":[[2,1,3,1],[2,2,3,2],[2,3,3,3],[2,4,2,5],[4,1,7,1],[4,2,5,2],[6,2,7,2],[8,1,11,1],[8,2,9,2],[10,2,11,2]]}
[]
[]
[null,"Pathway","Locus","Allele","Count (%)"]
[{"$nulls":4},"Control","Patient"]
[null,"mTOR","Polymorphic locus","Reference allele","2831974 (23.43)","2832199 (23.44)"]
[{"$nulls":3},"Variant allele","1887626 (34.12)","1887401 (35.18)"]
[null,null,"Pathogenic locus","Reference allele","2691080 (35.24)","2498073 (31.03)"]
[{"$nulls":3},"Variant allele","639320 (7.21)","832327 (10.35)"]
[null,"TGF-beta","Polymorphic locus","Reference allele","8248431 (23.52)","8246724 (23.93)"]
[{"$nulls":3},"Variant allele","5490769 (35.94)","5492476 (35.93)"]
[null,null,"Pathogenic locus","Reference allele","7443241 (32.43)","6908830 (30.10)"]
[{"$nulls":3},"Variant allele","1765959 (7.71)","2300370 (10.02)"]
[]
[null,null,"Supplementary Table-2: Percentage of the alleles at polymorphic and pathogenic loci in artificially constructed control and patient sets of pathway (mTOR/TGF-beta) genes. Base substitution in these loci was performed randomly so that reference base in polymorphic loci was substituted by variant base in approximatetly 40% of the samples in both groups. Reference base in pathogenic loci, was substituted by variant base in approximatetly 25% of the control group and 30% of the patient group. Difference bettween assigned valueas and the resulting values was due to randomness of the process."]