>BISON-CDK17 

MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQ
YTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEV
QSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRAS
LSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVS
LLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG
LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL
LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSND
EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRI
HALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF

>BISON-CDK14
 
XXXXXXXXXXXXXXXXXXXXXXXXXXXXX10:17 2020-09-07XXLKKEDTTFEEICVPKMSTRNCPGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH

>BISON-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPRKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSLKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRSMDYSTRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSV
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGTSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BISON-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BISON-CDK18

PIMSKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNEDLQLGPLGGDPQPESST
FSPTDSGKDLGQLSPGVQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLP
KPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEE
GAPCTAIREVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLXXXXX
XXIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEV
VTLWYRPPDVLLGSTEYSTPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPT
EETWPGVMALSEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALR
HPYFRSLGERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>BISON-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAAGAGLQ
HSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYS
SSSQQSAQYHPSHQAHRY

>BISON-CDK1 

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BISON-CDK15 

MGQELCAKALQPGCSCHRCWEGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFLLPKPQSLQNVFNRLGRAPEA
EDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDVSGVRLKPEMCDLLASYGKGH
HPAGFSKCW

>BISON-CDK13 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>BISON-CDKL1 

MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK
HPNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHK
HSCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY
GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVK
IPDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQ
HEKPTRKTLRQSRKHHCFTEACELQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI

>BISON-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLPEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDARNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNSSCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSITLQQVSKSPLSDDSEADLPPVEHQH

>BISON-CDKL3 

MEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPRSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKKPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSIQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BISON-CDKL4 

MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKH
NCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIP
EPEEMETLEEKFSDVHPVALSFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARN
EGRNRRRQQVPRFQS

>BISON-CDK20 

MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIED
SQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKI
SFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSEL
PIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG

>BISON-CDK2 

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BISON-CDK3 

MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKSYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BISON-CDK4 

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BISON-CDK5

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BISON-CDK6

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BISON-CDK7 

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BISON-CDK8

XVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGISMSACR
EIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPR
GMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLK
PLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSN
PYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPD
SKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPD
DKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRS
NPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BISON-CDK9 

MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>BOSGR-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAG
LQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
YSSSSQQSAQYHPSHQAHRY

>BOSGR-CDK18 

MTNGTRLCTLTPGVPGAGIQRQTQKAGRASLRGGHSANPPLLRCPGPSPGCSKSGDLIPG
SRRSGQPQREDGGQAEGRNRKRRLDPGFQMGQRGGHQGRASPRDWQRLWAGRAGEPGAES
GRACEKLWRGPGSPLLPALLPTSPFPSSPPPPAQVAASPRSRSPFPTSGRSSEGGQGPQQ
GAGPGPSAVAGGSRRTAAPRTRADISKRLSLPMDIRLPQEFLQKLQLESPDLPKPLTRMS
RRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAI
REVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVKIFMFQ
LLRGLAYCHRRKILHRDLKPQNLLINERELKLADFGLARAKSVPTKTYSNEVVTLWYRPP
DVLLGSTEYSTPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVM
ALSEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHPYFRSLG
ERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGLSSPPPAPTRGGQGGQRLPSRGT
EIGPGDGGSSPTRASLPGACREQGRASFPICCPGFLPVSSSSTHTPDRTPHLRVAP

>BOSGR-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPRKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRSMDYSTRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSV
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGTSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BOSGR-CDK15 

MGQELCAKALQPGCSCHRCWEGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPQSLQNVFNRLGRAPEA
EDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLA
SYGKGHHPAGFSKCW

>BOSGR-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BOSGR-CDK1 

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM
>BOSGR-CDK13 

MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGGGEASKSRSRHGHGGE
ERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHE
LWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPV
KTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATG
EKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESG
IDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNY
STTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGTLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHIST
SAGRGRGRGLPY

>BOSGR-CDK14 

MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKEDTTFEEICVTKMSTRNCPGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDRLSCHRSGEKKKINEVANNMKGFMDQFPFTPWGGFHLEEN

>BOSGR-CDK17 

MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQ
YTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEV
QSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRAS
LSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVS
LLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG
LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL
LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSND
EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRI
HALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF

>BOSGR-CDK16 

MAEDYWDGACGELEEKEVARPQPGPPPQAPPRRPRGTEVARAPPPVAMDRMKKIKRQLSM
TLRGGRGIDKTNGAPEQIGLDESGGGGGSDLGEAPTRAAPGEPRSVRGPLSSAPEIVHED
LKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEK
LTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVAL
KEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDD
CGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSI
PTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHF
IFRILGTPNEDTWPGILSNEEFRTYNYPKYRAEALLSHAPRVDSDGADLLTKLLQFEGRN
RISAEDAMKHPFFLSLGDRIHKLPDTTSIFALKEIQLQKEASIRSSSMPDSGKCRCDPCP
LPCPLAPIHLPACSPTAIRSAFPCRQASLPSGGHRILSHRPRPQQAAAGGMPHPSQGSPQ
LHPPCLLPAYLPDSCSHAHMSPAACLNTRPLACWPTHWPVCWVLTKLSSLLRLVCLSICL
CLFLSLSW

>BOSGR-CDK2

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BOSGR-CDK3

MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKSYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BOSGR-CDK4 

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BOSGR-CDK5

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BOSGR-CDK6

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BOSGR-CDK8

MSCNARPERRSQSPGARGDKGSDRAPHPSPRPSPSCAPGSSACVSPPHPGRPPPCRPAGC
PRRPRGASSCSCRSGRAGAAATGRRAGGFPGAAAAGASRRAPAPAAQRRDPRSPAPPAVT
MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWFECFHYNEDICREFE
TLDLVSVEHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANI
LVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDI
WAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHS
TLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLE
DPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQ
GPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQY
SHQTHRY
>BOSGR-CDK9 

MQRDAPPRAPAPAPRLPAPPIGAAAGASGGGGGGSGGGGGASAASAPPGLPGTTSPRGLG
GGRRAEEAGSAPRGRKWPWRRKWRGRGGAWSTAAGPGAGAAAAAAAAAVVAGSGGGGVLE
STMAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEG
FPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL
VKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAK
NSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL
ALISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVL
DPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR
NPATTNQTEFERVF

>BOSGR-CDKL4 

MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKH
NCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIP
EPEEMETLEEKFSDVHPVALSFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARN
EGRNRRRQQNQLLPLIPGSHISPTPDGRKQVLQLKFDHLPNI

>BOSGR-CDKL5 

SEIGIFNFILFTIVYILENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEY
VEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKL
CDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLF
PGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLL
DLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSSSTLSNRNQASKSAALQSHHRSN
SKDIQNLGVGLPRADEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNI
PHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGE
KQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSSTSRYFPSSCLDLNSPTSPTPTRHG
DTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGL
GYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPE
MTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFY
RVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEK
QGFFRSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQVSGA
CITLRLSDSAVTVSIIFAQPFIFSAYNVYRLGRGGGCHLPWAPQNISRQTPEWPWGGHFP
KSDFSLSQCSGSSPWISVPSSLESLVCFEIINLLLGLRPLRSDSQRCLWPVCQVLR

>BOSGR-CDKL1 

MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK
HPNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHK
HSCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY
GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVK
IPDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQ
HEKPTRKTLRQSRKHHCFTEACELQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI

>BOSGR-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDARNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSITLQQVSKSPLSDDSEADLPPVEHQH

>BOSGR-CDKL3 

MEMYETLEKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKKPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAKIAHTMSQDTKPVISEPPNPVNASTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSIQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BOSIH-CDKL1 

MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH
PNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKH
SCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKI
PDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQH
EKPTRKTLRQSRKHLPGLQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI

>BOSIH-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVISGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDVRNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSIALQQVSKSPLSDDSEADLPPVEHQH

>BOSIH-CDKL3 

MEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKKPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTVSQDTKPVISEPPNPVNPSTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BOSIH-CDKL5 

MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGL
PANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRT
LLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTTDSTNGENPSIKKSLFPLFNSKNHLKHSSSLKKLPVVTPPMVPNSDGP
DLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRF
QPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRS
ATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL

>BOSIH-CDK18 

MFSSICTRLHLFSYIHTILTRSHLFTPVLIHSHLSSPVLTFSHLFSPVLTHAHPFSPVLI
HSHLFSSILTSSDPFSSVRTCSHLFSSVLIHSHLFSSIPTCSHLFSSVLTRSHPFSPVLT
HSHPFSSFFTCSHPFSPVLIRSHLLSSILTSSHPFSPVLTRSHLSCPRTRHCSLPIMSKM
KNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNEDLQLGPLGGDPQPESSTFSPTDS
GKDLGQLSPGVQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLPKPLTRM
SRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTA
IREVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVKIFMF
QLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYR
PPDVLLGSTEYSTPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPG
VMALTEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHPYFRS
LGERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>BOSIH-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BOSIH-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPKKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPPEP
PGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRSMDYS
TRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSVSHLGESSSY
QGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTG
TSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BOSIH-CDK15 

MGQELCAKALQPGCSCHRCREGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPQSLQNVFNRNEASGEI
LCLSHFSRLGRAPEAEDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDEESLFT
VSGVRLKPEMCDLLASYGKGHHPAGFSKCW

>BOSIH-CDK1 

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BOSIH-CDK13 

MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGGGEASKSRSRHGHGGE
ERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHE
LWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPV
KTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATG
EKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESG
IDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNY
STTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGSLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHIST
SAGRGRGRGLPY

>BOSIH-CDK14 

MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKEDTTFEEICVTKMSTRNCPGMDSMIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH

>BOSIH-CDK17 

MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESYRSAPSHHPLRATLTLLRFSPRSSLLTH
SFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGR
PPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDG
ESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPP
FDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH
EEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSM
HNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSN
EVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGT
PSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEA
MKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFVINHFTCRS

>BOSIH-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAG
LQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
YSSSSQQSAQYHPSHQAHRY

>BOSIH-CDK2 

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BOSIH-CDK3

MDMFQKVEKIGEGTYGVVYKAMNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKSYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BOSIH-CDK4 

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BOSIH-CDK5 

PTSRPLHVLHFLSILTQHLLHNLTHPQPQFSLQTSNLCVPASPYSSPRPLLPISRPSRSS
AFVIDLLTWPLQPLPVADTLEPSAAPLCHITTHRALCRAQPLPQISSLAPPVSAVTPSHA
ACCPGRGFLSWESVPHPFPTPPLLPLGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPS
SALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSF
LFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLW
YRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQ
WPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF
SDFCPP

>BOSIH-CDK6 

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRLAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BOSIH-CDK7 

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BOSIH-CDK8 

MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BOSIH-CDK9 

MQRDAPPRAPAPAPRLPAPPIGAAAGASGGGGGGSGGGGGASAASAPPGLPGTTSPRGPG
GGRRAEEAGSAPRGRKWPWRRKWRGRGGAWSTAAGPGAGAAAAAAAAAVVAGSGGGGVLE
SAMAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEG
FPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL
VKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAK
NSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL
ALISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVL
DPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR
NPATTNQTEFERVF

>BOSMU-CDK13 

MPSSSDTALGGGGGLSWAEKKLEXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKATKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHE
LWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPV
KTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATG
EKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESG
IDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNY
STTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGTLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHIST
SAGRGRGRGLPY

>BOSMU-CDK19 

MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAAGAGLQ
HSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYS
SSSQQSAQYHPSHQAHRY

>BOSMU-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BOSMU-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPRKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRSMDYSTRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSV
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGTSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BOSMU-CDK17 

MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESYRSAPSHHPLRATLTLLRFSPSSSLLTH
SFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGR
PPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDG
ESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPP
FDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH
EEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSM
HNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSN
EVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGT
PSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEA
MKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF

>BOSMU-CDK16 

MPLHGHPWGRVSGLRVLRESPTSPMAGSISAAAPENACCRALCSHSEAAPKGANTSPVVP
FPSASHPSLNTQVAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDLGE
APTRAAPGEPRSVRGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPP
RKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYI
KLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTL
HDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRD
LKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMW
GVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPNEDTWPGILSNEEFRTYNYPKYRAE
ALLSHAPRVDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGDRIHKLPDTTSIFALK
EIQLQKEASIRSSSMPDSGRPAYRVVDTEF

>BOSMU-CDK14 

MSTRNCPGMDSVIKPLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKS
SSAGKESPKVRRHSSPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKV
IRLQEEEGTPFTAIREASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHP
GGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPS
HTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERI
FLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPK
NRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLS
NSKH

>BOSMU-CDK1 

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BOSMU-CDK15 

MGQELCAKALQPGCSCHRCWEGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPQSLQNVFNRLGRAPEA
EDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDVSGVRLKPEMCDLLASYGKGH
HPAGFSKCW

>BOSMU-CDK18 

PIMSKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNEDLQLGPLGGDPQPESST
FSPTDSGKDLGQLSPGVQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLP
KPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEE
GAPCTAIREVSLLRNLKHANIVTLHDLVHTERSLTLVXXXXDRDLKQYLDHCGNLMSMHN
VKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEV
VTLWYRPPDVLLGSTEYSTPLDMWGVGCIQYEMATGRPRFPGEELHLIFRLLGTPTEETW
PGVMALSEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHPYF
RSLGERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>BOSMU-CDK20 

MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIED
SQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPNPQVWPEITELPDYNKI
SFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSEL
PIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG

>BOSMU-CDK2 

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BOSMU-CDK3 

MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKSYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BOSMU-CDK4 

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BOSMU-CDK5 

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BOSMU-CDK6 

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BOSMU-CDK7 

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BOSMU-CDK8 

MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BOSMU-CDK9 

MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>BOSMU-CDKL1 

MPKQGQGQIVAIKMFLESEDDPVIKKIALREIRMLKQLKHPNLVNLIEVFRRKRRLHLVF
EYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKHSCIHRDVKPENILVTKQSVI
KLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVP
LWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKIPDPEDMEPLELKFPNISYSA
LGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQHEKPTRKTLRQSRKHLPGLQC
LPQLTSSSILPALDNKKHCYNTKKLNYHFPNI
>BOSMU-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDARNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKESK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRNCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSITLQQVSKSPLSDDSEADLPPVEHQH

>BOSMU-CDKL3 

MEMYETLEKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKKPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAKIAHTMSQDTKPVISEPPNPVNASTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSIQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BOSMU-CDKL4 

MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKH
NCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIP
EPEEMETLEEKFSDVHPVALSFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARN
EGRNRRRQQNQLLPLIPGSHISPTPDGRKQVLQLKFDHLPNI

>BOSMU-CDKL5 

MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGL
PANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRT
LLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLR
KLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPA
LQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL

>BOSTA-CDK1 
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BOSTA-CDK14 

MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKEDTTFEEICVTKMSTRNCPGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH

>BOSTA-CDK13 

MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGGGEASKSRSRHGHGGE
ERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHE
LWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPV
KTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATG
EKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESG
IDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNY
STTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGSLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHIST
SAGRGRGRGLPY

>BOSTA-CDK17 

MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQ
YTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEV
QSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRAS
LSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVS
LLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG
LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL
LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQENWPGVSSND
EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRI
HALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF

>BOSTA-CDK18 

MSKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNEDLQLGPLGGDPQPESSTFS
PTDSGKDLGQLSPGVQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLPKP
LTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGA
PCTAIREVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVK
IFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVT
LWYRPPDVLLGSTEYSTPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPTEE
TWPGVMALTEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHP
YFRSLGERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>BOSTA-CDK11B 

MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE
HERRKRHREEQDKARREWERQKRRELAREHSRRERDRLEQLERKRERERKMREQQKEQRE
QKERERRAEERRKEREARREVSAHHRTVREDYSDKVKASHWSRSPLRPPRERLEPGDSRK
PVKEEKVEERDLLSDLQDVSDSERKTSSAESSSAESGSGSEEEEEEEEEEEGSSSEESEE
EEEEEEEEEEEETGSNSEDVSGQSAEEVSEEEMSEDEERENENHVLVVPESRFDHDSGES
EEGEEEAGEGTPQSSALTEGDFVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRI
EEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIV
VGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLK
TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSV
GCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNDLPAVKKMTFTEYPYNNL
RKRFGALLSDQGFDLMNKFLTYFPGRRVNAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQ
QRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF

>BOSTA-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BOSTA-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPKKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFFFLPWGALDLLDHMLTLDPSKRCTAEQTLQSD
FLKDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEP
VKNSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLL
NIHSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPE
ASSTPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAGKQTG
HESH

>BOSTA-CDK15

MGQELCAKALQPGCSCHRCREGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VVKEKSTHNGSNLDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDA
LLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSK
LPNYNPEWFPLPKPQSLQNVFNRLGRAPEAEDLASQMLKGFPRDRVSAQEALVHNYFSVL
PAQLHQLPDEESLFTVSGVRLKPEMCDLLASYGKGHHPAGFSKCW

>BOSTA-CDK16 

MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDLGEAPTRAAPGEPRSVR
GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
LFPGSTVEEQLHFIFRILGTPNEDTWPGILSNEEFRTYNYPKYRAEALLSHAPRVDSDGA
DLLTKLLQFEGRNRISAEDAMKHPFFLSLGDRIHKLPDTTSIFALKEIQLQKEASIRSSS
MPDSGRPAYRVVDTEF

>BOSTA-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAG
LQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
YSSSSQQSAQYHPSHQAHRY

>BOSTA-CDK2 

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BOSTA-CDK20 

MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIED
SQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKI
SFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSEL
PIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG

>BOSTA-CDK3

MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKRYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BOSTA-CDK4 
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BOSTA-CDK5 

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BOSTA-CDK6 

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRLAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BOSTA-CDK7 

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BOSTA-CDK8 

MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BOSTA-CDK9

MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>BOSTA-CDKL1 
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH
PNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKH
SCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKI
PDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSARQH
EKPTRKTLRQSRKHLPGLQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI
>BOSTA-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVISGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDVRNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSIALQQVSKSPLSDDSEADLPPVEHQH

>BOSTA-CDKL3 

MEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BOSTA-CDKL4 

MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKH
NCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIP
EPEEMETLEEKFSDVHPVALSFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARN
EGRNRRRQQNQLLPLIPGSHISPTPDGRKQVLQLKFDHLPNI

>BOSTA-CDKL5

MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGL
PANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRT
LLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLR
KLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPA
LQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL

>BOSTH-CDK18 

MGERGGHQGRASPRDWQRLWAGRAGGPGAESGRACEKLWRGLGSPLLPALLPTSPFPSSP
PPPAQVAASPGSRSPFPTSGRSSEGGQGPQQGAGPGPSAVAGGSRRTAAPRTRASDIGFG
KLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLRNLKH
ANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHRR
KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS
TPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVMALTEFRAYNF
PRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHPYFRSLGERVHQLEDTA
SLFSLKEIQLQKDPGYRGLAFQQPGRGLSSPPPAPTRGGQGGQRLPSRGTEIGPGDGGSS
PTQASLPGACREQGRAGFPICCPGFLPVSSSSTHTPDRTPHLRVAP

>BOSTH-CDK10 

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BOSTH-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPKKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPPEP
PGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRSMDYS
TRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSVSHLGESSSY
QGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTG
TSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BOSTH-CDK15

MGQELCAKALQPGCSCHRCREGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPQSLQNVFNRLGRAPEA
EDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLA
SYGKGHHPAGFSKCW

>BOSTH-CDK1 

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BOSTH-CDK13 

MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGGGEASKSRSRHGHGGE
ERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHE
LWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPV
KTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATG
EKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESG
IDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNY
STTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGSLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHIST
SAGRGRGRGLPY

>BOSTH-CDK14 

MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKEDTTFEEICVTKMSTRNCPGMDSMIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSAGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDRLSCHRSGEKKKINEVANNTKGFMDQFPFTPWGGFHLEEN

>BOSTH-CDK17 

MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESYRSAPSHHPLRATLTLLRFSPRSSLLTH
SFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGR
PPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDG
ESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPP
FDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH
EEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSM
HNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSN
EVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGT
PSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEA
MKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGVFVINHFTCRS

>BOSTH-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAG
LQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
YSSSSQQSAQYHPSHQAHRY

>BOSTH-CDK16 

MRVVGAAAVTLERPPHVLPLGNLALYGAHSALHQPLQASWHLPAPGLPSQGIRLLLPLPA
HWPWASHSLSSALTRGALLEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRK
ISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKL
DKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHD
IIHTEKSLTLVFEYLVRLGGHGSWGRWGDGQEPQDVTLFPLPALLASGQDLKQYLDDCGN
IINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTK
TYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFR
ILGTPNEDTWPGILSNEEFRTYNYPKYRAEALLSHAPRVDSDGADLLTKLLQFEGRNRIS
AEDAMKHPFFLSLGDRIHKLLTVSGAWEWTSWWGTLCNRIAADSWAVVLSSSCATSDGVR
HMPLFTYVICCFLQKSLLAFSFFTFHGNFQT

>BOSTH-CDK3 

MDMFQKVEKIGEGTYGVVYKARNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKRYLFQLLQGVNFCHT
HRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCML
ERFCC

>BOSTH-CDK4 

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BOSTH-CDK2 

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BOSTH-CDK5 

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BOSTH-CDK6 

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRLAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BOSTH-CDK7 

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BOSTH-CDK8

MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BOSTH-CDK9 

MQRDAPPRAPAPAPRLPAPPIGAAAGASGGGGGGSGGGGGASAASAPPGLPGTTSPRGPG
GGRRAEEAGSAPRGRKWPWRRKWRGRGGAWSTAAGPGAGAAAAAAAAAVVAGSGGGGVLE
SAMAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEG
FPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVL
VKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAK
NSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQL
ALISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVL
DPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSR
NPATTNQTEFERVF

>BOSTH-CDKL2 

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVISGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDVRNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLS
ATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSIALQQVSKSPLSDDSEADLPPVEHQH

>BOSTH-CDKL3 

MEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLP
QVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELK
AKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKRPKEIKVRV
TKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTMSQDTKPVISEPPNPVNPSTNAIGMKD
DPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHED
TGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEV
KQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFW

>BOSTH-CDKL1 

MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH
PNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKH
SCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKI
PDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQH
EKPTRKTLRQSRKHLPGLQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI

>BUBBU-CDK15

MGQELCAKALQPGCSCHRCWEGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGL
QAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
VHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPKPLSLQNVFNRLGRAPEA
EDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDEESLFTVSGVRLKPEMCDLLA
SYGKGHHPAGFSKCW

>BUBBU-CDK12 

MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEA
APLGTVIKPLVEYDDISSDSDTFSDDLAFKLDRRENDERRGTDRSDRLHKHRHHQHRRTR
DLLKTKQSEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGA
SYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPIFLPRKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGK
VKLDENSEKHPVLKDTKVQGTRDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLP
TTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQAN
SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQ
RPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVK
NSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEAS
STPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRSMDYSTRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSV
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGTSSSGASLNWGASAQSSAYGKVYRGPTRVPPRGGRGRGVPY

>BUBBU-CDK17 

MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESSRSAPSHHPLRATLTLLRFSPRSSLLTH
SFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGR
PPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDG
ESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPP
FDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEH
EEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSM
HNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSN
EVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGT
PSQENWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEA
MKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF

>BUBBU-CDK1

MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKST
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM

>BUBBU-CDK14 
MCDLIEPQPAEKIGKMKKLRRTLSDSFSRIALKKDDTTFEEICVTKMSTRNCPGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPTNQVKRVHSENNACINFNKSSSSGKESPKVRRHS
SPSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAI
REASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQ
LLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRP
PDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPG
VHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYF
SDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH

>BUBBU-CDK13 

MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKDRHREHRRRDGQRGSGEASKSRSRHGHGGE
ERAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSSGTLKNDKAKT
KPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSIGAKEKEQH
VALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGD
DLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQV
YKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALD
FKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIK
CSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWS
CGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRK
LREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPERFLHAEAMH
HSKMTESLPLWQDCHELWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVL
PSSQLKPQGNSNAAPVKTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQ
QQLNKINLPAGILATGEKQTDPSTPQQESSKPLGGIQPSSQNMQPKVEPDAAQAAVQSAF
AVLLTQLIKAQQSKQKDVLLEERENGSGHEAPLQLRPPPEPSTPASGQDDLIQHQDMRLL
DLTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALL
QLLAQHQPQDDPKRESGIDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPL
ERRSFMGNSDIQSLDNYSTTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDK
DHRFEYSHGPIAVLANSSDPSTGPESTHPLPAKMHNYNYGGTLQETPGGHGLMHGQTWTS
PAQGPGYSQGYRGHISTSAGRGRGRGLPY

>BUBBU-CDK19 

MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAG
LQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLG
YSSSSQQSTQYHPSHQAHRY

>BUBBU-CDK10

MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD
EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ
DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF
GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT
SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL
LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR
P

>BUBBU-CDK16 

MPGFQESCVIPGFHSGWVGTAAGSCQCASLGFGGPMRVRRLLGWDPFPSLPPAQVAMDRM
KKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDLGEAPTRAAPGEPRSVRGPLS
SAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADI
RLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKS
KLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLD
KDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLAD
FGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPG
STVEEQLHFIFRILGTPNEDTWPGILSNEEFRTYNYPKYRAEALLSHAPRVDSDGADLLT
KLLQFEGRNRISAEDAMKHPFFLSLGDRIHKLPDTTSIFALKEIQLQKEASIRSSSMPDS
VAGGQRGRASLPH

>BUBBU-CDK18

MSKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNEDLQLGPLGGDPQPESSTFS
PTDSGKDPGQLSPGMQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLPKP
LTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGA
PCTAIREVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVK
IFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVT
LWYRPPDVLLGSTEYSTPLDMWGVGCIQYEMATGRPLFPGSTVKEELHLIFRLLGTPTEE
TWPGVMALSEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSLLLYESKSRVSAEAALRHP
YFRSLGERVLQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>BUBBU-CDK20

MEQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQVLREIKALQEIED
SQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRRTQRPLAQAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFAPDGNRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPVRRGLPFGGVG
EITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQVWNEASRT
KELWRQLCLRRWSSCKASQMTLGTQTWKQYYLRRSELEFRMASGRPEDFTCRALAGHKGE
IDDLAYISTSECRFDGQDKSVVCTVSSDGTVRAWDLHEGMELWSSPVQSAALVNLVTYPR
LQLVVTVDERGLIKVWEAENGCEQAAFLLPMYSSALEACDIPEGPLLLAACAEGALYTLT
VPWLQLLSRVNVFPGNPTSLLCSPDQQWVFASTQNSDLSPEVFYTQSLLCRSEDETPAST
TLPIWLMSRACWTPDEAARLMVMHRNDSGLQLVITTYELGSRKSRDRVEILVQQIASFLL
PDTMMPPHLMKGHGSQVILLVSGSELVLFTIHGLQLVAFQDHQRPITSMWVDQTRVITSS
FDLSLRVYMWNKENKFPVLKSCYHLLGGSHRWASGFTHVESDSMSIVGVEARNIGTSILR
SYYFQVQCG

>BUBBU-CDK2

MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHGRCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
TPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>BUBBU-CDK3

MAMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLETEGVPSTAIREISLLKELKH
PNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKSYLFQLLQGVSFCHS
HRVIHRDLKPQNLLINELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFY
STAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSF
PKWTSKGLEEVVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCMR
EHFCH

>BUBBU-CDK4

MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEG
DAE

>BUBBU-CDK5

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>BUBBU-CDK6 

MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSPQPIEKFVTDIDEQGKDLLLKCLTFNPAKRISAYSALSHPYF
HDLERRKENLDSHLPPSQNSSEMNTA

>BUBBU-CDK7

MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPSRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPG
PTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF

>BUBBU-CDK8

MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY

>BUBBU-CDK9

MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>BUBBU-CDKL5

MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRADEGL
PANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRT
LLSPSGRNNRSEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSVGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKEASREGTSSFHARQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTTDSTNGENPSIKKSLFPLFNSKNHLKHSSSLKKLPVVTPPMVPNSDGP
DLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRF
QPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRS
ATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL

>BUBBU-CDKL2

MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVISGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRL
PEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQEL
QLKVQKDARNISLSKKSQIRKKEKEKDESLGEERKTLVVQNTNADPQTKDSKVFKIKGSK
TDGEKVEKASRASNASCLNDNGMSPVKIVPSTSLRDCTNGSVDQTRNPGMTIPPLTHNLS
ATAPTINSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQ
ANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLH
TPSIALQQVSKSPLSDDSEADLPPVEHQH

>BUBBU-CDKL3

MQKKPGLKMEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIK
FLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRA
IEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELV
LKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSP
IFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFI
EKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSIWGKELEKEKK
SKEIKVRVTKVKGGKGDILEPKKIVCEGGRCQQVAAEIAHTMSQDTKPVISEPPNPVNPS
TNAIGMKDDPCAGGSTVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQ
VISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQS
KEMKGMEVKQIKVLKRESKRTDSSKIPTLLNADQYQEKQEDGDGHCKGKNLKRNRLFFWM
Q

>BUBBU-CDKL1

MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH
PNLVNLIEVFRRKRRLHLVFEYCDHTVLHELDRHQRGVPEHXVKSITWQTLQAVNFCHKH
SCIHRDVKPENILVTKQSVIKLCDFGFARLLTGPSDYYTDYVATRWYRAPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKI
PDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQH
EKPTRKTLRQSRKHLPGLQCLPQLTSSSILPALDNKKYCYNTKKLNYHFPNI

>BUBBU-CDKL4

MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHEH
NCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIP
EPEEMETLEEKFSDVHPVALNFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARN
EGRNRRRQQNQLLPLIPGSHISPTPDGRKQVLQLKFDHLPNI

>HUMAN-CDK8
MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDDKGDKKNQQQQQGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY

>HUMAN-CDK7
MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF

>HUMAN-CDK11B

MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
ERFELGDGRKPGEARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG
SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED
EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ
ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPI
TSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVK
TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
LWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEK
IWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKH
EYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTT
NQGASAAGPGFSLKF

>HUMAN-CDK20

MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED
NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI
SFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSEL
PIPQRLGGPAPKAHPGPPHIHDFHVDRPLEESLLNPELIRPFILEG
>HUMAN-CDK5

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>HUMAN-CDK2
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>HUMAN-CDK4
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEG
NPE

>HUMAN-CDK9
MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>HUMAN-CDK1
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM

>HUMAN-CDK6
MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
QDLERCKENLDSHLPPSQNTSELNTA

>HUMAN-CDK11A
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK
ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPG
EARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEE
EEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVV
PESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGC
RSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKA
QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKH
LHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGA
KEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVK
KMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDP
SMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFS
LKF

>HUMAN-CDK13
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGS
PASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHRRRDGQRGGSEASKSRSRHSHSGE
ERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKSSKEPPSAYKEPPKAY
REDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSPS
PYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSGKSRSRSPYSSRHS
RSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEATKAA
EAAAKAAKASNTSTPTKGNTETSASASQTNHVKDVKKIKIEHAPSPSSGGTLKNDKAKTK
PPLQVTKVENNLIVDKATKKAVIVGKESKSAATKEESVSLKEKTKPLTPSIGAKEKEQHV
ALVTSTLPPLPLPPMLPEDKEADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDD
LSKSPEEKKTATQLHSKRRPKICGPRYGETKEKDIDWGKRCVDKFDIIGIIGEGTYGQVY
KARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDF
KKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKC
SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
GCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKL
REEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHEL
WSKKRRRQKQMGMTDDVSTIKAPRKDLSLGLDDSRTNTPQGVLPSSQLKSQGSSNVAPVK
TGPGQHLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGE
KQTDPSTPQQESSKPLGGIQPSSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKD
VLLEERENGSGHEASLQLRPPPEPSTPVSGQDDLIQHQDMRILELTPEPDRPRILPPDQR
PPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGG
IDYQAGDTYVSTSDYKDNFGSSSFSSAPYVSNDGLGSSSAPPLERRSFIGNSDIQSLDNY
STASSHSGGPPQPSAFSESFPSSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPIAVLANS
SDPSTGPESTHPLPAKMHNYNYGGNLQENPSGPSLMHGQTWTSPAQGPGYSQGYRGHIST
STGRGRGRGLPY

>HUMAN-CDK12
MPNSERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDMGLVTPEA
ASLGTVIKPLVEYDDISSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSR
DLLKAKQTEKEKSQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLH
KEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPSGA
SYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQR
SVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSP
AYSRHSSSHSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKES
KGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGK
VKLDENSEKHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLP
TTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQAN
SQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQ
RTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWG
KRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQ
LIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFM
KQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLW
YRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVW
PDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL
KDVELSKMAPPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVK
NSSPAPPQPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNI
HSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEAS
STPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHIL
PPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEH
QALRPMEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPALTESLVQTLVKNRTFSGSL
SHLGESSSYQGTGSVQFPGDQDLRFARVPLALHPVVGQPFLKAEGSSNSVVHAETKLQNY
GELGPGTTGASSSGAGLHWGGPTQSSAYGKLYRGPTRVPPRGGRGRGVPY

>HUMAN-CDK10

MAEPDLECEQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQ
TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYC
EQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTA
DFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLP
GTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLL
HFLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPATSEGQSKRCKP

>HUMAN-CDK16
MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
MPDSGRPAFRVVDTEF

>HUMAN-CDK3
MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF
PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL
QRFRH

>HUMAN-CDK14
MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKDDTTFDEICVTKMSTRNCQGMDSVIK
PLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKTSSTGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH

>HUMAN-CDK15

MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGL
QAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
MHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEA
EDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLA
SYQKGHHPAQFSKCW

>HUMAN-CDK18
MIMNKMKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPPQECST
FSPTDSGEEPGQLSPGVQFQRRQNQRRFSMEDVSKRLSLPMDIRLPQEFLQKLQMESPDL
PKPLSRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE
EGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMH
NVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNE
VVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTP
TEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAAL
SHSYFRSLGERVHQLEDTASIFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF

>HUMAN-CDK19
MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTG
AGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
LGYSSSSQQSSQYHPSHQAHRY

>HUMAN-CDK17
MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQ
YTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEV
QSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRAS
LSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVS
LLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG
LAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL
LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNE
EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRI
HALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF

>HUMAN-CDKL5
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSAKRKPYHVESSTLSNRNQAGKSTALQSHHRSNSKDIQNLSVGLPRADEGL
PANESFLNGNLAGASLSPLHTKTYQASSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDPKPSEGPGTKYLKSNSRSQQNRHSFMESSQSKAGTLQPNEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQIAEPSTSRYFPSSCLDLNSPTSPTPTRHSDTRT
LLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RSSVKETSREGTSSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFF
RSMKKKKKKSQTVPNSDSPDLLTLQKSIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLR
KLLHLSSASNHPASSDPRFQPLTAQQTKNSFSEIRIHPLSQASGGSSNIRQEPAPKGRPA
LQLPDGGCDGRRQRHHSGPQDRRFMLRTTEQQGEYFCCGDPKKPHTPCVPNRALHRPISS
PAPYPVLQVRGTSMCPTLQVRGTDAFSCPTQQSGFSFFVRHVMREALIHRAQVNQAALLT
YHENAALTGK
>HUMAN-CDKL3
MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP
QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELK
AKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRV
IKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQE
DPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGME
VKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
>HUMAN-CDKL1
MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK
HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK
HNCIHRDVKPENILITKHSVIKLCDFGFARLLAGPSDYYTDYVATRWYRSPELLVGDTQY
GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK
IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE
HNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI
>HUMAN-CDKL2
MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
DSGADLPQMEHQH
>HUMAN-CDKL4
MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIH
NCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDTQYGS
SVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISIP
EPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRKARN
EGRNRRRQQQAPKSAFPRLFLKTKICQVQRNETQTSGNQILPNGPILQNSMVTVMTNINS
AVYQVTVLHLLSENFEVKS
>MOUSE-CDK8
MDYDFKVKLSSERERVEDLFEYEGCKVGRGTYGHVYKAKRKDGKDDKDYALKQIEGTGIS
MSACREIALLRELKHPNVISLLKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKP
VQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKH
KVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLT
EEEPDEKGDKKTQQQQQGNNHTNGTGHPGNQDSGHAQGPPLKKVRVVPPTTTSGGLIMTS
DYQRSNPHAAYPNPGPSTSQPQSSMGYSATSQQPPQYSHQTHRY

>MOUSE-CDK20

MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGIPNQALREIKALQEIED
SQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHAQRPLAPAQVKSYLQMLLKGVAFCHA
NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGGRLYTHQVATRWYRAPELLYGARQ
YDQGVDLWAVGCIMGELLNGSPLFPGENDIEQLCCVLRILGTPSPRVWPEITELPDYNKI
SFKEQAPVPLEEVLPDASPQALDLLGQFLLYPPRQRIAASQALLHQYFFTAPLPAHPSEL
PIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG
>MOUSE-CDK7
MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
CSLPDYVTFKSFPGVPLQHIFIAAGDDLLELIQGLFLFNPCTRTTASQALKTKYFSNRPG
PTPGCQLPRPNCPVEALKEPANPTVATKRKRAEALEQGILPKKLIF

>MOUSE-CDK1

MEDYIKIEKIGEGTYGVVYKGRHRVTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRH
PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLHQILQGIVFCH
SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR
YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
FPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM

>MOUSE-CDK11B
MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
LREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREEYSDKGKVGHWSRSPLRPPR
ERFEMGDNRKPVKEEKVEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
EEEEGSTSEESEEEEEEEEEEEEEETGSNSEEASEQSAEEVSDEEMSEDEDRENENHILV
VPESRFDRDSGDSEEGEEEVGEGTPQSSAPTEGDYVPDSPALSPIELKQELPKYLPALQG
CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILK
AQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLSGVK
HLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLG
AKEYSTAVDMWSVGCIFGELLTQKPLFPGKSDIDQINKIFKDLGTPSEKIWPGYNDLPAV
KKMTFSEYPYNNLRKRFGALLSDQGFDLMNKFLTYYPGRRINAEDGLKHEYFRETPLPID
PSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGF
SLKF

>MOUSE-CDK3
MDVFQKVEKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAVREISLLKELKH
PNIIKLLDVVHREKKLYMVFEFLTQDLKRHMDSSPTSELPLPVVKSYLAQLLEGVSFCHS
HRVIHRDLKPQNLLLDGLGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
STAVDISIGCIFAEMVTGKALFPGDSEIDQLFRIFRTLGTPSEATWPGVSQMPDYQSSFP
KWSRKGLEEIVPSLGPEGKDLLLRLLQYDPSQRISAKTALAHPYFSPGHSLAPQQCTAGR
SSR

>MOUSE-CDK5

MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYP
MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP

>MOUSE-CDK2
MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINAEGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMHLVCTQHHAKCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVS
APHPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVV
PPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

>MOUSE-CDK4
MAATRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAAGGGLPVSTVREVALL
RRLEAFEHPNVVRLMDVCATSRTDRDIKVTLVFEHIDQDLRTYLDKAPPPGLPVETIKDL
MRQFLSGLDFLHANCIVHRDLKPENILVTSNGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR
EVSLPRGAFAPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKEES
DAE

>MOUSE-CDK9
MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRQTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDKYELFEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF

>MOUSE-CDK6
MEKDSLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDIIGLPGE
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYF
QDLERYKDNLNSHLPSNQSTSELNTA

>MOUSE-CDK16
MDRMKKIKRQLSMTLRGGRGIDKTNGVPEQIGLDESGGGGGSDLGEAPTRIAPGELRSVR
GPLSSAPEIVHEDMKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
EYLDKDLKQYLDDCGNVINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFRTYNYPKYRAEALLSHAPRLDSDGA
DLLTKLLQFEGRNRISAEDARKHPFFLSLGERIHKLPDTTSIFALKEVQLQKEANIRSTS
MPDSGRPAFRVVDTEF

>MOUSE-CDK13
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLF
LAAPGAAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRPGGRQKRRRGPRAGQEAEKRRV
FSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGNGGS
PASSSGTQRRAEGSERRPRRDRRSSSGRSKERHREHRRRDGTRSGSEASKARSRHGHSGE
ERAEAAKSGSSSSSGGRRKSASATSSSSSSRKDRDLKAHRSRTKSSKEPPSAYKEPPKAY
REDKSEPKAYRRRQRSLSPLGGRDESPVSHRASQSLRSRKSPSPAGGGSSPYSRRLPRSP
SPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVLRRSAKSRSRSPYSSRH
SRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKA
AEAAAKAAKASNASTPTKGNTETGASVSQTNHVKEVKKLKTEHAPSPSSGGTVKSDKAKT
KPPLQVTKVDNNLTVEKATKKTVVGKESKPAATKEEPVSTKEKSKPLTPSTGAKEKEQHV
ALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDD
LSKSPEEKKTAAQLHSKRRPKICGPRYGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVY
KARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDF
KKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKC
SNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSC
GCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKL
REEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHEL
WSKKRRRQKQMGMTDDLSTIKAPRKDLSLGLDDSRTNTPQGVLPPAQLKSQSNSNVAPVI
TGPGQPLNHSELAILLNLLQSKSSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGE
KQTDPSTPQQESSKSLGGVQPSQTIQPKVETDAAQAAVQSAFAVLLTQLIKAQQSKQKDA
MLEERENGSGHEAPLQLRPPLEPSTPGSGQDDLIQHQDRRILELTPEPDRPRILPPDQRP
PEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKREGGI
DYPTGDTYVPSSDYKDNFGSSFSAAPYVSSDGLGSSSAAAPLEARSFIGNSDIQSLDNYS
TASSHTGGPPQTSAFTESFASSVAGYGDIYLNAGPMLFSGDKDHRFEYSHGPITVLTNSN
DPSTGPESTHPLPAKMHNYNYGGNLQENPGGPSLMHGQTWTSPAQGPGYSQGYRGHISTS
AGRGRGRGLPY

>MOUSE-CDK14
MCDLIEPQPAEKIGKMKKLRRTLSESFSRIALKKEDTTFDEICVTKMSTRNCQGTDSVIK
HLDTIPEDKKVRVQRTQSTFDPFEKPANQVKRVHSENNACINFKSSSAGKESPKVRRHSS
PSSPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIR
EASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQL
LRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPP
DVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGV
HSLPHFKPERFTVYSSKSLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFS
DLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAFGKNNSYGKSLSNSKH

>MOUSE-CDK12
MPNSERHGGKKDGSGGASGTSQPSSGGGSSNSRERHRLVSKHKRHKSKHSKDVGLVTPEA
ASLGTIIKPLVEYDDISSDSDTFSDDTAFKSDRRENEERRGTDRSDRLHRHRHHQHRRSR
DLLKTKQTEKEKNQEVSKSGSMKDRVSGSSKRSVEGSDDYGKAQLSKSGSKESRSSKMHK
EKTRKERELKSGYKDRSKSHRKRETPKSYKTVASPKRRSRSPHRKWSDSSKQDDSPSGAS
YGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQRS
VSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPA
YSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESK
SSPIILPKKEKLEVKESGLESKKLPRSIKSEKSTPDTELVTVAHSNPEVKHCLDTGKVRL
DENLQKHPAKDLKAQGTKDVKPVAPKEVIVTSKETETSEKETLPPLPTITSPPPLPATTP
PPQTPPLPPLPPLPAIPLQPPLPPPQPPFSQVPVSSTSILPSSPHPRTSTLSSQTNSQPP
VQVSMKTQVSITAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPAKKEKEQRTRH
LLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCV
DKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLVHQ
SVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLM
EGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPP
ELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVI
KLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVE
LSKMAPPDLPHWQDCHELWSKKRRRQRQSGIVIEDPPPSKASRKETTSGTTAEPVKNNSP
APPQPAPVKAEPGPGDAVGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNP
EMQQQLEALNQSISALTEASSQQQDSESIAPEESLKEVPSVPVVLPPAEQTTPEASNTPA
DMQNVLAVLLSQLMKTQEPAGNLEENTNDKNSGPQGPRRTPTMPQEEAAACPPHILPPEK
RPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALR
PMEYSTRSHPNRTYGNTDGPETGFSSADTDERSSGPALTESLVQTPVKNRTFSGSVSHLG
ESNSYQGTGSVQFPGDQDLRFTRVPLALHSVVGQPFLKSEGNSNSVVHAETKLQNYGELG
PGTTGANSSGTTLQWGGPAQSYGKPYRGAARVLPRGGRGRGVPY

>MOUSE-CDK15
MGQELCAKRLQPGCSCYHRSEGGEAHSCQRSQPGSTEPAVFELTEASSSTASFHPRGLEA
ASAQKLKSKRPRSNSDSFQEENLRQGLPWKKSLPFGAASSYLNLEKLGEGSYAKVYKGIS
RINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMH
TDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLAD
FGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPG
VSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPKPQSLQIVWDRLGGVPEAED
LASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLKPEMCDLSASY
RKRHHLVGVNKCW

>MOUSE-CDK18
MNKMKNFKRRLSLSVPRPETIEESLAEFTEQFNQLHTQTNEDGTDEPEQLSPGMQYQQRQ
NQRRFSMEDLNKRLSLPMDIRLPQEFLQKLQLENPGLPKPLTRMSRRASLSDIGFGKLET
YVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIV
TLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMNMHNVKIFMFQLLRGLAYCHHRKILH
RDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPID
MWGVGCILYEMATGKPLFPGSTVKEELHLIFRLLGTPTEESWPGVTSISEFRAYNFPRYL
PQPLLSHAPRLDTEGINLLSSLLLYESKSRMSAEAALNHPYFQSLGDRVHQLHDTASIFS
LKEIQLQKDPGYRGLAFQHPGRGKSRRQSIF

>MOUSE-CDK10
MAEVDLESDQIRLKCIRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTQ
TDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYC
EQDLASLLENMPTPFSEAQVKCIMLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTA
DFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLP
GTSEIHQIDLIVQLLGTPSENIWPGFSKLPLAGQYSLRKQPYNNLKHKFPWLSEAGLRLL
NFLFMYDPKKRATSGDCLESSYFKEKPLPCEPELMPTFPHHRNKRAAPAAAEGQSKRCRP

>MOUSE-CDK17
MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEESSSKDNEPIVKNGRPPTSHSVHSFLHQ
YTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEV
QSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQISSPPFDQPMSRRSRRAS
LSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVS
LLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRG
LAYCHRRKVLHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVL
LGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGVSSND
EFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVPAEEAMKHVYFRSLGPRI
HALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF

>MOUSE-CDK19
MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGIS
MSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKP
MQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLF
NSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQED
IKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKH
KVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLN
EDEPEEKGDKNQPQQQNPHQQPAAPAQQTAAPPQAPPPQQSSAQTNGTAGGATAGGGGAG
AGLQHSQDPGLNQVPPNKKPRIGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQST
LGYSSSQQSTQYHSSHQTHRY

>MOUSE-CDKL5
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRE
LKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLI
KAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSP
ELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYS
NPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQ
RLLDRSPSRSTKRKPYHVESSTLSNRNQSTKGAALQTHHRSNSKDIQNLSVGLPRAEEGL
PANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFN
IDTKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSP
SYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRT
LLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTS
PFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVA
RPSVKESSREGASSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPS
PRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHADQLKEKEKQGFF
RSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLR
KLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQATGGSSNIRQEPTPKGRPA
LQLPGSSLLRYNGWKHSRSRSSQPDEVIFLASHEKWKQ
>MOUSE-CDKL3
MEMYETLGKVGEGSYGTVMKCKHKDTGRIVAIKIFYEKPEKSVNKIATREIKFLKQFRHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGHPFLPSSSDLDLLHKIVLKVGNLTPHLHNIFSKSPIFAGVVLP
QVQHPKTARKKYPKLNGLLADIVHACLQIDPAERTSSTDLLRHDYFTRDGFIEKFIPELR
AKLLQEAKVNSFIKPKENFKENEPVRDEKKSVFTNTLLYGNPSLYGKEVDRDKRAKELKV
RVIKAKGGKGDVPDQKKPEYEGDHRQQGTADDTQPSSLDKKPSVLELTNPLNPSENSDGV
KEDPHAGGCMIMPPINLTSSNLLAANLSSNLSHPNSRLTERTKKRRTSSQTIGQTLSNSR
QEDTGPTQVQTEKGAFNERTGQNDQISSGNKRKLNFPKCDRKEFHFPELPFTVQAKEMKG
MEVKQIKVLKRESKKTDSSKIPTLLSMDPNQEKQEGGDGDCEGKNLKRNRFFFSR
>MOUSE-CDKL2
MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLKLFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDIWAIGCLVIEMLMGQPLFPGESDIDQLHHIMTCLGNLIPRHQELFYKNPVFAGVRL
PEVKDAEAEPLESRYPKLPEAVISLAKKCLHIDPDKRPFCADLLRHDFFQMDGFAERFSQ
ELQLKIEKDARNNSLPKKSQNRKKEKDDALGEERKTLVVQDTNADPKIKDSKVFKVKGSK
IDVEKMEKGSRASNANCLHDNGTNHKGLASTSLRDCSNVNIDHSRNPGTAIPPLTHNLSA
VAPGINAGMGTIPGVQNYRVDEKTKKYCNPFVKPNQPPPAGIYNMNVSTSVSGEKYLLQA
NKKRKEYPKADVRLPELNYNHLPELRALEGIARNSRLIKKENKCLSESRIPSLAAIDLHV
SSVASHQGAGSPLSDDSEADLPRMEHQH
>MOUSE-CDKL1
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKRFLETEDDPVIKKIALREIRMLKQLKH
PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEPLVKNITWQTLQAVNFCHKH
NCIHRDVKPENILITKQSAIKLCDFGFARLLTGPGDYYTDYVATRWYRSPELLVGDTQYG
PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSMNQYFSGVKI
PDPEDMETLELKFPNISYSALGFLKGCLHMDPAERLTCEQLLQHPYFDSIREVGELTRQH
DKPARKTLRQSRKHLTGLQYLPQLTSSRILPALDNKKYHCSTKRFNYHFPNI
>MOUSE-CDKL4
MEKYEKLAKIGEGSYGVVFKCRNKSSGQVVAIKKFVESEDDRVVRKIALREIRMLKQLKH
PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVSDGVIKSVLWQTLQALNFCHKH
NCIHRDVKPENILITKQGMIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTKYGS
SVDVWAVGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFRSNQFFRGISIP
EPEDMETLEEKFSNVQPVALSFMKGCLKMNPDERLTCAQLLDSAYFESFQEDQMKRKARS
EGRSRRRQQNQLLPLIPGSHISPTPDGRKQVVQLKFDHLPNI
>BOSIN-CDK1
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYXHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKSTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDSQIKKM
>BOSIN-CDK2
MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINADGSIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMHLVCTQHHARCCGEHRRNGRHSLCPLCSYLEVAASQGGGMTAVSTPYPVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
>BOSIN-CDK3
MDMFQKVEKXGEGTYGVVYKAXNKETGQLVALKKIRLDLETEGVPSTAIREISLLKELKHPNIVRLLDVVHSEKKLYLVFEFLSQDLKKYMDSTPASELPLHLVKXYLFQLLQGVNFCHTHRVIHRDLKPQNLLISELGTIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKFYSTAVDIWSIGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPSEAMWPGVTQLPDYKGSFPKWTSKGLEEXVPNLEPEGQDLLLQLLQYDPSRRISAKAALAHPYFSSTETSSAPHQCMLERFCC
>BOSIN-CDK4
MATSXYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGAGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKAEGDAE
>BOSIN-CDK5
MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
>BOSIN-CDK6
MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCXFAEMFRRKPLFRGSSDVDQLGKILDCCCRQCYYLCGEWGCGRRAVSCRARHDVWPDCSALEACVLLVWLLWQLPFAWLSSRSLVLLCCLLGVFSDASTIRGRGAQWPGNPSLFTGLHVPIEHPVISQVGFALFGFVFLGKGWSATQLTSLWNTEKGNENPRFHPSVCG
>BOSIN-CDK7
MAVDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKVSCSLFLCLEGDMCSLPDFVTFKSFPGIPLQHIFIAAGDDLLDLIQGLFLFNPCTRITATQALKTKYFSNRPGPTPGCQLPRPNCPAEALKEQSNPAMATKRKRTEALEQGGLPKKLIF
>BOSIN-CDK8
MSACREIALLRELKHPNVISLQKVFLSHADRKVWLLFDYAEHDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKDWEDIKKMPEHSTLMKDFRRNTYTNCSLIKYMEKHKVKPDSKAFHLLQKLLTMDPIKRITSEQAMQDPYFLEDPLPTSDVFAGCQIPYPKREFLTEEEPDDKGDKKNQQQQPGNNHTNGTGHPGNQDSSHTQGPPLKKVRVVPPTTTSGGLIMTSDYQRSNPHAAYPNPGPSTSQPQSSMGYSTTSQQPPQYSHQTHRY
>BOSIN-CDK9
MAKQYDSVECPFCDEVTKYEKLAKIGQGTFGEVFKAKHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDKYELFEKVELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNPATTNQTEFERVF
>BOSIN-CDK10
MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTDEIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGTSEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNLLFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGRP
>BOSIN-CDK11B
MSASAKPPALGELDPGPGEKPGGRPLLAWAPVFSHRSEKIALGQSDGSPEEQVLTVTVTETTVIEADXGVWGARALTYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVILSRTVLGEHTGLLVNLSLIPVMGGLALCTATEMSFNFLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAAELQFYTSTAAVAMLVPAWIFFMDLPVIGRSGRSFRYSQDVVLLLLADGVLFHLQSVTAYALMGRISPVTFSVLTQMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRRELAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTVREDYSDKVKASHWSRSPLRPPRERLEPGDSRKPVKEEKVEERDLLSDLQDVSDSERKTSSAESSSGDCSPGPAQLSHHRAGPKFTAACFLPKAESGSGSEEEEEEEEEEEGSSSEESEEEEEEEEEEEEEETGSNSEDVSGQSAEEVSEEEMSEDEERENENHVLVVPESRFDHDSGESEEGEEEAGEGTPQSSALTEGDFVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREIXTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYNDLPAVKKMTFTEYPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRVNAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
>BOSIN-CDK12
MPNPERHGGKKDGSGGASGTLQPSSGGGSSNSRERHRLGSKHKRHKSKHSKDMGLVTPEAAPLGTVIKPLVEYDDISSDSDTFSDDLAFKVDRRENDERRGTDRSDRLHKHRHHQHRRTRDLLKTKQTEKEKNLEASSKSGSTKDRISGSSKRSNEENDDHGKAQISKSSNKESRSSKLHKEKTRKERELKSGHKDRSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSPKQDDSPSGASYGQDYDLSPPRSHTSSNYDSYKKSPGSTSRRQSISPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSGSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPIFLPKKENSSVEAKDSGLEPKKLPRGVKLEKSAPDTELVNVTHLNTEVKNSLDTGKVKLDENSEKHPVLKDTKVQGTKDSKPVALKEEIVTPKETETSEKETLPPLPTVTSPPPLPTTTPPPQTPPLPPLPPLPAIPQQPPLPPPQPTFSQVLSSSTSTLPPSVHPRTSTLSSQANSQPSVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLLGDDDMDSPKETLPSKPVKKEKEQRPRHLLTDLPLPPELPGGDPSPPDSPEPKAITPPQQPYKKRPKICCPRYGERRQTESDWGKRCVDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQLMEGLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIKLPYFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMDPPDLPHWQDCHELWSKKRRRQRQSGVLVEEPPPPKASRKETISGTSAEPVKNSSPAPPQPAPGKVEPGAGDAIGLGDITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLEALNQSISALTAATSQQQDSEPTAPEESLKEIAPAPAVQPSAEQTTPEASSTPADMQNMLAVLLSQLMKTQEPAGNLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHLPHEHQALRSMDYSTRPHPNRTYGNTDGPETGFSATDTDERNSGPALTESLAQTLVKNRTFSGSVSHLGESSSYQGTGSVQFPGDQDLRFARVPLALHSVVGQPFLKAEGSSNSVVHAETKLQNYGELGPGTTGTSSSGASLNWGASAQSSAYGKVYRGPTRVPPRXGRGRGVPY
>BOSIN-CDK13
MPSSSDTALGGGGGLSWAEKKLEERRKRRRFLSPQQPPLLLPLLQPQLLQPPPPPPPLLFLAAPGTAAAAAAAAAASSSCFSPGPPLEVKRLARGKRRAGGRQKRRRGPRAGQEAEKRRVFSLPQPQQDGGGGASSGGGVTPLVEYEDVSSQSEQGLLLGGASAATAATAAGGTGGSGGSPASSSGTQRRGEGSERRPRRVRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAEAGKSGSSSSSGGRRKSASATSSSSSSRKDRDPKAHRSRTKSSKEPPSAYKEPPKAYREDKTEPKAYRRRQRSLSPLGGRDDSPVSHRASQSLRNRKSPSPAGGGSSPYSRRLARSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRSRSPYSPVIRRSAKSRSRSPYSSRHSRSRSRHRLSRSRSRHSSISPSTLTLKSSLAAELNKNKKARAAEAARAAEAAKAAEAAKAAEAAAKAAKAASTSTPTKGNTETGASASQTNHVKDVKKLKTEHAPSPSSGGTLKNDKAKTKPPLQVTKVDNNLIVDKATKKAVVVGKESKSAATKEEPVSLKEKTKPLTPSTGAKEKEQHVALVTSTLPPLPLPPMLPEDKDADSLRGNISVKAVKKEVEKKLRCLLADLPLPPELPGGDDLSKSPEEKKTATQLHNKRRPKICGPRFGEIKEKDIDWGKRCVDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFNTMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVEPSKMPPPDLPLWQDCHELWSKKRRRQKQMGMTDDVSTVKAPRKDLSLGMDDSRTSTPQSVLPSSQLKPQGNSNAAPVKTGPGQQLNHSELAILLNLLQSKTSVNMADFVQVLNIKVNSETQQQLNKINLPAGILATGEKQTDPSTPQQESSKPLGGIQPSQNMQPKVEPDAAQAAVQSAFAVLLTQLIKAQQSKQKDVLLEERENGSGHEAPLQLRPPPEPATPASGQDDLIQHQDMRLLELTPEPDRPRILPPDQRPPEPPEPPPVTEEDLDYRTENQHVPTTSSSLTDPHAGVKAALLQLLAQHQPQDDPKRESGIDYQAGDTYVPSSDYKDNFGSSSFSSAPYVSNDGLGSASAPPLERRSFMGNSDIQSLDNYSTTSSHSGGPPQPSAFSESFPSSVAGYGDIYLNTGPMLFSGDKDHRFEYSHGPIAVLANSSDPSTGPESTHPLPAKMHNYNYGGSLQETPGGHGLMHGQTWTSPAQGPGYSQGYRGHISTSAGRGRGRGLPY
>BOSIN-CDK14
MVIASLLKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRTFGKNNSYGKSLSNSKH
>BOSIN-CDK15
MGQELCAKALQPGCSCHRCWEGGNAHSCQRSAPVMTEAAIELTDLKEASCSMTSFHPRGLQAVHARKFKSKRPRSNSDSFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEYVHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVCDLPRVTWPGFSRLPVCSPKWFPLPKPQSLQNVFNRLGRAPEXEDLASQMLKGFPRDRVSAQEALVHNYFSVLPAQLHQLPDEESLFTVSGVRLKPEXCDLLASYGKGHHPAGFSKCW
>BOSIN-CDK16
MPGFQESCVIPGFHSGWVGTAAGSCQCASLGFRGPMRVRRLLGWDPFPSLPPAQVAMDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDLGEAPTRAAPGEPRSVRGPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSLPADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPNEDTWPGILSNEEFRTYNYPKYRAEALLSHAPRVDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGDRIHKLPDTTSIFALKEIQLQKEASIRSSSMPDSVAGGQRGRASLPH
>BOSIN-CDK17
MKGLPSTVVCVAVAFLRVFVPDGFCSPTRLESYRSAPSHHPLRATLTLLRFSPRSSLLTHSFSGFFKSHSVDRMKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISIEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQEXWPGVSSNDEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHAKNRRQSMLF
>BOSIN-CDK18
MSKMKNFKRRFSLXVPRTETIEESLXEFTEQFNQLHNRRNEDLQXGPLGGDPQPESSTFSPTDSGKDLGQLSPGVQYRRQNQRRFSMEDISKRLSLPMDIRLPQEFLQKLQLESPDLPKPLTRMSRRASLSDIGFGKLETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLRNLKHANIVTLHDLVHTERSLTLVFEYLDRDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHRRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPLDMWGVGCIQYEMATGXPLFPGSTVKEELHLIFRLLGTPTEETWPGVMALTEFRAYNFPRYLPQPLLSHVPRLDPDGINLLSSXLLYESKSRVSAEAALRHPYFRSLGERVHQLEDTASLFSLKEIQLQKDPGYRGLAFQQPGRGKNRRQSIF
>BOSIN-CDK19
MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDEPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPQQQNSTQTNGTAGGAGAGPAGAGLQHSQDSGLNQVPPNKKPRLGPSGTNSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSAQYHPSHQAHRY
>BOSIN-CDK20
MEQYCILGRIGEGAHGIVFKAKHVETGEIVAXKKVALRRLEDGIPNQVLREIKALQEIEDSQYVVQLKAVFPHGAGFVLAFEFMLSDLAEVVRHTQRPLAQAQVKSYLQMLLKGVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGNRLYTHQVATRWYRAPELLYGARQYDQGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRILGTPSPQVWPEITELPDYNKISFKEQAPVPLEEVLPDASPQALDLLGRFLLYPPQQRISASQALLHHYFFTAPLPVHPSELPIPQRPGGPAPKAHPGPPHVHDFHVDRPLEESLLNPELIRPFIPEG
>BOSIN-CDKL1
MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVNLIEVFRRKRRLHLVFXYCDHTVLHELDRHQRGVPEHLVKSITWQTLQAVNFCHKHSCIHRDVKPENILVTKQSVIKLCDFGFARLLTGXSDYYTDYVATRWYRSPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQHVFSTNQYFSGVKIPDPEDMEPLELKFPNISYSALGLLKGCLHMNPAERLTCEQLLQHSYFDSIREIGDSAKQHEKPTRKTLRQSRKHLXGLQCLPQLTSSSILPALDNKKHCYNTKKLNYHFPNI
>BOSIN-CDKL2
MEKYENLGLVGEGSYGMVMKCRNKDSGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRHENLVNLLEVCKKKKRWYLVFEFVDHTVLDDLELSPNGLDYQLVQKYLFQVIXGIGFCHSHNIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYGKAVDVWAIGXLVTEMLMGEPLFPGDSDIDQLYHIMVCLGNLIPRHQELFYKNPVFAGVRLPEIKETVPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFHMDGFAERFPQELQLKVQKDARNISLSKKSQIRKKEKEKDESLGEERKTLVVQDTNADPQTKDSKVFKIKGSKTDGEKVEKXSRASNASCLNDNGMSPVKIVPSTSLRDCSNGSVDQTRNPGMAIPPLTHNLSATAPTITSGMGTISGIQSYRVDEKTKKYCIPFVKPNKHSPPGAYNINVTTLVASEKSLLQANKKRREYSKTDVRLPELNYNHLPELKALEGIARNSRLIKKENKNLSESRIPSLATIDLHTPXIALQQVSKSPLSDDSEADLPXVEHQH
>BOSIN-CDKL3
MEMYETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPEKSVNKIAMREIKFLKQFRHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDVYXDYVATRWXRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLTPHLQNIFSKSPIFAGVVLPQVQHPKSARKKYPKLNGLLADIVHACLQIDPAERMSSTDLLHHEYFTRDGFIEKFIPELKAKLLQEAKVNSFIKPKENSKENDFMKEERKTIYTNTLQSTSVWGKELEKEKXPKEIKVRVTKVKGGKGDILEPKKIVCEGGHCQQVAAEIAHTVSQDTKPVISEPPNPVNPSTNAIGMKDDPCAGGGMVMPPINLTSSNLMASNPNSNLSHSNSRLTERAKKRRTSSQSIGQVISNRHEDTGSTQSQMEKCVFNERTSQTDQMANGNKRKLNFPRSDRKEFHFPELPFIIQSKEMKGMEVKQIKVLKRESKRTDSSKIPTLLNADQYQEKQENTGNAQTERKKNLPDVE
>BOSIN-CDKL4
MEKYEKLAKIGEGSYGVVFKCRNKTSGQVVAIKKFVESEDDPVVKKIALREIRMLKQLKHPNLVNLIEVFRRKRKMHLVFXYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHKHNCIHRDVKPENILITKQGIIKICDFGFARILIPGDAYTDYVATRWYRAPELLVGDTQYGSSVDIWATGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNQFFHGISIPEPEEMETLEEKFSDVHPVALSFMKECLKMNPDDRLTCAQLLESPYFDSFQEDQIKRKARNEGRNRRRQQNQLLPLIPGSHISPTPDGRKQVLQLKFDHLPNI
>BOSIN-CDKL5
MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSAKRKPYHVESSTLSNRNQASKSAALQSHHRSNSKDIQNLGVGLPRXDEGLPANESFLNGNLAGATLSPMHTKTYQAGSQPGSTSKDLTNNNIPHLLSPKEAKSKTEFDFNIDPKPSDGPGTKYLKSSSRSQQNRHSFMESSQSKAGTLQPGEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQIAESSTSRYFPSSCLDLNSPTSPTPTRHGDTRTLLSPSGRNNRSEGTLDSRRTTTRHSKTMEEXKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKXRAKGLDGSLSIGQGMAARANSLXXXXPQPGEQLPPEMTVARSSVKESSREGTSSFHVRQKSEGGAYHDPHSDDGAAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSESSSGTNHSKRQPAFDPWKSPENISHSEQLKEKEKQGFFRSMKKKKKKSQTVPNSDGPDLLTLQKAIHSASTPSSRPKEWRPEKISDLQTQSQPLKSLRKLLHLSSASNHPASSDPRFQPLTTQQAKNSFSEIRIHPLSQASGGSSNIRQEPTPKGRPALQLPGQMDPGWHVSSVTRSATEGPSYSEQLGAKSGPNGHPYNRTNRSRMPNLNDLKETAL