{"text_format":"3","workbook":"xls","n_sheets":3,"sheets":["Legend","RBP table","RBP families"],"not_rendered":{"external_links":1,"defined_names":2},"read":"whole","date_system":"1904","formulas":"cached_only"}

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["S2. Legend for RBP table"]
[]
["Column name","Description"]
["gene name","official gene name according to Ensembl v75"]
["description","gene description according to Ensembl v75"]
["gene id","Ensembl gene id"]
["protein id","Ensembl protein id"]
["number of domains","total number of Pfam defined protein domains"]
["domains[count]","Pfam domain [ count ]"]
["paralogous family ID","given ID for each paralogous family grouped by 20% homology"]
["members of paralogous family ","gene names of members in paralogous family"]
["representative family member","chosen one representative family member against which all other family members are compared for % identity scores for representation"]
["paralog [ % identity representative member:paralog , % identity paralog: representative member]","offical gene name of paralog [pairwise alignment score representative family member to paralog, and paralog to representative family member"]
["consensus RNA target","consensus RNA target"]
["putative RNA target","putative RNA targets determined by literature reports "]
["supporting evidence (# pubmed ID)","supporting evidence why protein was taken into census , given numbers are the pubmed IDs"]
["category in Baltz et al.","identified in RNA-protein crosslinking experiment by Baltz et al. 2012"]
["category in Castello et al.","identified in RNA-protein crosslinking experiment by Castello et al. 2012"]
["found in both human mass spec","overlapping proteins found in Castello et al. and Baltz et al."]
["human cell lines mass spec","union of proteins identified in Castello et al. and Baltz et al."]
["category in Kwon et al. mouse mESC","mouse homolog identified in RNA-protein crosslinking experiment by Kwon et al. 2012"]
["Toronto RBPDB","RBPDB database http://rbpdb.ccbr.utoronto.ca/"]
["GO RNA related category","Gene Ontology IDs related to RNA "]
["GO RNA related category description","Gene Ontology terms related to RNA "]
["GO general category","all Gene Ontology IDs associated with gene"]
["GO general category description","all Gene Ontology terms associated with gene"]
["OMIM","genes for which genetic diseases are listed in Online Mendelian Inheritance in Man database "]

{"sheet":"RBP table","index":1,"n_rows":1543,"n_cols":24,"rows_kept":1543,"flags":["formulas_cached_only"]}
["gene name","description","gene id","protein id","number of domains","domains[count]","paralogous family ID","members of paralogous family ","representative family member","paralog [ % identity representative member:paralog , % identity paralog: representative member]","consensus RNA target","putative RNA target","supporting evidence (# pubmed ID)","category in Baltz et al.","category in Castello et al.","found in both human mass spec","human cell lines mass spec","category in Kwon et al. mouse mESC","Toronto RBPDB","GO RNA related category","GO RNA related category description","GO general category","GO general category description","OMIM"]
["RPS11","ribosomal protein S11 [Source:HGNC Symbol;Acc:10384]","ENSG00000142534","ENSP00000470447",1,"Ribosomal_S17[1]","family-1","RPS11",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003735,GO:0022627,GO:0005840,GO:0006412,GO:0019843,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,translation,rRNA binding,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0022627,GO:0005840,GO:0006412,GO:0019843,GO:0005829,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,cytosolic small ribosomal subunit,ribosome,translation,rRNA binding,cytosol,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ERAL1","Era G-protein-like 1 (E. coli) [Source:HGNC Symbol;Acc:3424]","ENSG00000132591","ENSP00000254928",2,"MMR_HSR1[1],KH_1[1]","family-10","ERAL1",".",".","rRNA","rRNA",20604745,"RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0019843,GO:0043024,GO:0000028","RNA binding,rRNA binding,ribosomal small subunit binding,ribosomal small subunit assembly","GO:0003723,GO:0005525,GO:0003924,GO:0015093,GO:0016021,GO:0005622,GO:0007264,GO:0015684,GO:0019843,GO:0043024,GO:0005759,GO:0005743,GO:0000028","RNA binding,GTP binding,GTPase activity,ferrous iron transmembrane transporter activity,integral to membrane,intracellular,small GTPase mediated signal transduction,ferrous iron transport,rRNA binding,ribosomal small subunit binding,mitochondrial matrix,mitochondrial inner membrane,ribosomal small subunit assembly","."]
["DDX27","DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Source:HGNC Symbol;Acc:15837]","ENSG00000124228","ENSP00000360828",2,"Helicase_C[1],DEAD[1]","family-100","DDX27",".",".","rRNA","putative rRNA","DRS1 yeast homolog","helicase","novel",1,1,1,".",".",".","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus","."]
["DEK","DEK oncogene [Source:HGNC Symbol;Acc:2768]","ENSG00000124795","ENSP00000380414",2,"SAP[1],DEK_C[1]","family-1000","DEK",".",".","mRNA","mRNA","This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0003676,GO:2001032,GO:0003677,GO:0042393,GO:0005634,GO:0006366,GO:0007165,GO:0006357,GO:0016568,GO:0019079,GO:2000779","nucleic acid binding,regulation of double-strand break repair via nonhomologous end joining,DNA binding,histone binding,nucleus,transcription from RNA polymerase II promoter,signal transduction,regulation of transcription from RNA polymerase II promoter,chromatin modification,viral genome replication,regulation of double-strand break repair","."]
["PSMA6","proteasome (prosome, macropain) subunit, alpha type, 6 [Source:HGNC Symbol;Acc:9535]","ENSG00000100902","ENSP00000261479",2,"Proteasome[1],Proteasome_A_N[1]","family-1001","PSMA6",".",".","unknown","unknown",7681138,".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0016070,GO:0016071","RNA binding,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process","GO:0004298,GO:0005839,GO:0051603,GO:0004175,GO:0005634,GO:0005737,GO:0019773,GO:0006511,GO:0003723,GO:0005739,GO:0000932,GO:0016363,GO:0030017,GO:0005515,GO:0051059,GO:0035639,GO:0030016,GO:0005829,GO:0005654,GO:0005844,GO:0006915,GO:0042981,GO:0043066,GO:0044281,GO:0000209,GO:0002474,GO:0000278,GO:0016032,GO:0002479,GO:0006521,GO:0006977,GO:0010467,GO:0016070,GO:0016071,GO:0031145,GO:0034641,GO:0042590,GO:0051437,GO:0051439,GO:0051092,GO:0050727,GO:0000082,GO:0051436","threonine-type endopeptidase activity,proteasome core complex,proteolysis involved in cellular protein catabolic process,endopeptidase activity,nucleus,cytoplasm,proteasome core complex, alpha-subunit complex,ubiquitin-dependent protein catabolic process,RNA binding,mitochondrion,cytoplasmic mRNA processing body,nuclear matrix,sarcomere,protein binding,NF-kappaB binding,purine ribonucleoside triphosphate binding,myofibril,cytosol,nucleoplasm,polysome,apoptotic process,regulation of apoptotic process,negative regulation of apoptotic process,small molecule metabolic process,protein polyubiquitination,antigen processing and presentation of peptide antigen via MHC class I,mitotic cell cycle,viral process,antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent,regulation of cellular amino acid metabolic process,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,gene expression,RNA metabolic process,mRNA metabolic process,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,cellular nitrogen compound metabolic process,antigen processing and presentation of exogenous peptide antigen via MHC class I,positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,positive regulation of NF-kappaB transcription factor activity,regulation of inflammatory response,G1/S transition of mitotic cell cycle,negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","."]
["TRIM56","tripartite motif containing 56 [Source:HGNC Symbol;Acc:19028]","ENSG00000169871","ENSP00000305161",3,"zf-C3HC4[1],zf-B_box[2]","family-1002","TRIM45,TRIM56,TRIM71,TRIM3,TRIM2","TRIM45","TRIM56[22,17],TRIM71[23,15],TRIM3[22,17],TRIM2[22,17]","unknown","unknown",21074459,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005515,GO:0008270,GO:0046872,GO:0005622,GO:0004842,GO:0005737,GO:0005829,GO:0051607,GO:0070534,GO:0032608,GO:0034340,GO:0045087,GO:0032481,GO:0032479","protein binding,zinc ion binding,metal ion binding,intracellular,ubiquitin-protein ligase activity,cytoplasm,cytosol,defense response to virus,protein K63-linked ubiquitination,interferon-beta production,response to type I interferon,innate immune response,positive regulation of type I interferon production,regulation of type I interferon production","."]
["TRIM71","TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase [ Homo sapiens (human) ]","ENSG00000206557","ENSP00000373272",10,"NHL[6],zf-RING_5[1],Filamin[1],zf-B_box[2]","family-1002","TRIM45,TRIM56,TRIM71,TRIM3,TRIM2","TRIM45","TRIM56[22,17],TRIM71[23,15],TRIM3[22,17],TRIM2[22,17]","ncRNA","miRNA",24602972,".",".",".",".",1,".","GO:0035198,GO:0000932,GO:0060964,GO:0010586","miRNA binding,cytoplasmic mRNA processing body,regulation of gene silencing by miRNA,miRNA metabolic process","GO:0004842,GO:0035198,GO:0005515,GO:0008270,GO:0000932,GO:0005622,GO:0000082,GO:0021915,GO:0051865,GO:0071310,GO:0060964,GO:0008543,GO:0010586,GO:0051246,GO:0072089,GO:2000177,GO:0035278,GO:2000637,GO:0001843","ubiquitin-protein ligase activity,miRNA binding,protein binding,zinc ion binding,cytoplasmic mRNA processing body,intracellular,G1/S transition of mitotic cell cycle,neural tube development,protein autoubiquitination,cellular response to organic substance,regulation of gene silencing by miRNA,fibroblast growth factor receptor signaling pathway,miRNA metabolic process,regulation of protein metabolic process,stem cell proliferation,regulation of neural precursor cell proliferation,negative regulation of translation involved in gene silencing by miRNA,positive regulation of gene silencing by miRNA,neural tube closure","."]
["UPF2","UPF2 regulator of nonsense transcripts homolog (yeast) [Source:HGNC Symbol;Acc:17854]","ENSG00000151461","ENSP00000348708",4,"MIF4G[3],Upf2[1]","family-1003","UPF2",".",".","mRNA","mRNA","This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0016070,GO:0016071,GO:0006406,GO:0000184","RNA binding,RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005488,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0048471,GO:0035145,GO:0010467,GO:0016070,GO:0016071,GO:0001889,GO:0031100,GO:0006406,GO:0000184","binding,RNA binding,protein binding,nucleus,cytoplasm,cytosol,perinuclear region of cytoplasm,exon-exon junction complex,gene expression,RNA metabolic process,mRNA metabolic process,liver development,organ regeneration,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["FARS2","phenylalanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:21062]","ENSG00000145982","ENSP00000316335",3,"FDX-ACB[1],tRNA-synt_2d[2]","family-1004","FARS2,FDXACB1","FARS2","FDXACB1[21,15]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000049,GO:0004812,GO:0043039,GO:0004826,GO:0008033,GO:0006418,GO:0006432","tRNA binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation,phenylalanine-tRNA ligase activity,tRNA processing,tRNA aminoacylation for protein translation,phenylalanyl-tRNA aminoacylation","GO:0005524,GO:0000049,GO:0004812,GO:0005737,GO:0043039,GO:0000166,GO:0000287,GO:0004826,GO:0005739,GO:0005759,GO:0010467,GO:0008033,GO:0006418,GO:0006432","ATP binding,tRNA binding,aminoacyl-tRNA ligase activity,cytoplasm,tRNA aminoacylation,nucleotide binding,magnesium ion binding,phenylalanine-tRNA ligase activity,mitochondrion,mitochondrial matrix,gene expression,tRNA processing,tRNA aminoacylation for protein translation,phenylalanyl-tRNA aminoacylation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 14; COXPD14"]
["FDXACB1","ferredoxin-fold anticodon binding domain containing 1 [Source:HGNC Symbol;Acc:25110]","ENSG00000262028","ENSP00000460095",2,"FDX-ACB[1],DUF2431[1]","family-1004","FARS2,FDXACB1","FARS2","FDXACB1[21,15]","tRNA","putative tRNA","This gene encodes a protein which contains a ferredoxin-fold anticodon-binding domain which is contained in a subset of phenylalanyl tRNA synthetases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]",".",".",".",".",".",".","GO:0000049,GO:0004826,GO:0008033,GO:0006432","tRNA binding,phenylalanine-tRNA ligase activity,tRNA processing,phenylalanyl-tRNA aminoacylation","GO:0005524,GO:0000287,GO:0000049,GO:0004826,GO:0008033,GO:0006432","ATP binding,magnesium ion binding,tRNA binding,phenylalanine-tRNA ligase activity,tRNA processing,phenylalanyl-tRNA aminoacylation","."]
["ALKBH8","alkB, alkylation repair homolog 8 (E. coli) [Source:HGNC Symbol;Acc:25189]","ENSG00000137760","ENSP00000415885",4,"Methyltransf_11[1],2OG-FeII_Oxy_2[1],RRM_1[1],DUF1891[1]","family-1005","ALKBH8,KIAA1456","ALKBH8","KIAA1456[17,25]","tRNA","tRNA","20123966, 21285950",".",".",".",".",".",1,"GO:0003723,GO:0016300,GO:0030488","RNA binding,tRNA (uracil) methyltransferase activity,tRNA methylation","GO:0000166,GO:0003676,GO:0016706,GO:0008168,GO:0055114,GO:0003723,GO:0005515,GO:0016491,GO:0046872,GO:0016300,GO:0005634,GO:0005737,GO:0005829,GO:0015630,GO:0006974,GO:0008152,GO:0030488","nucleotide binding,nucleic acid binding,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors,methyltransferase activity,oxidation-reduction process,RNA binding,protein binding,oxidoreductase activity,metal ion binding,tRNA (uracil) methyltransferase activity,nucleus,cytoplasm,cytosol,microtubule cytoskeleton,cellular response to DNA damage stimulus,metabolic process,tRNA methylation","."]
["ZNF579","zinc finger protein 579 [Source:HGNC Symbol;Acc:26646]","ENSG00000218891","ENSP00000320188",6,"zf-C2H2_4[1],zf-H2C2_2[1],zf-C2H2[4]","family-1006","ZNF579",".",".","unknown","unknown","established RBP ","candidate mRNA binder",".",".",1,".",".",".",".","GO:0046872,GO:0003677,GO:0005634,GO:0006351,GO:0006355","metal ion binding,DNA binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["POLR2B","polymerase (RNA) II (DNA directed) polypeptide B, 140kDa [Source:HGNC Symbol;Acc:9188]","ENSG00000047315","ENSP00000391452",6,"RNA_pol_Rpb2_7[1],RNA_pol_Rpb2_4[1],RNA_pol_Rpb2_1[1],RNA_pol_Rpb2_3[1],RNA_pol_Rpb2_5[1],RNA_pol_Rpb2_6[1]","family-1007","POLR1B,POLR3B,POLR2B","POLR1B","POLR3B[30,30],POLR2B[28,27]","mRNA","mRNA","This gene encodes the second largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with at least two other polymerase subunits, forms a structure within the polymerase that maintains contact in the active site of the enzyme between the DNA template and the newly synthesized RNA. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,".",".","GO:0032549,GO:0008380,GO:0000398,GO:0006370","ribonucleoside binding,RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0005515,GO:0046872,GO:0003677,GO:0003682,GO:0001055,GO:0003899,GO:0032549,GO:0005634,GO:0005654,GO:0005665,GO:0006351,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","protein binding,metal ion binding,DNA binding,chromatin binding,RNA polymerase II activity,DNA-directed RNA polymerase activity,ribonucleoside binding,nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,transcription, DNA-templated,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["WDR12","WD repeat domain 12 [Source:HGNC Symbol;Acc:14098]","ENSG00000138442","ENSP00000261015",8,"WD40[7],NLE[1]","family-1008","WDR12,WDR37","WDR12","WDR37[23,20]","rRNA","putative rRNA",16043514,".",".",".",".",".",".","GO:0043021,GO:0030687,GO:0000463,GO:0000466,GO:0042273","ribonucleoprotein complex binding,preribosome, large subunit precursor,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal large subunit biogenesis","GO:0005515,GO:0043021,GO:0005634,GO:0005730,GO:0005654,GO:0030687,GO:0070545,GO:0008283,GO:0007219,GO:0000463,GO:0000466,GO:0042273","protein binding,ribonucleoprotein complex binding,nucleus,nucleolus,nucleoplasm,preribosome, large subunit precursor,PeBoW complex,cell proliferation,Notch signaling pathway,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal large subunit biogenesis","."]
["RPF1","ribosome production factor 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:30350]","ENSG00000117133","ENSP00000359688",1,"Brix[1]","family-1009","RPF1",".",".","rRNA","putative rRNA","RPF1 yeast homolog , 11864606","RNAbinding",".",".",1,1,".","GO:0003723,GO:0019843,GO:0006364","RNA binding,rRNA binding,rRNA processing","GO:0003723,GO:0019843,GO:0005730,GO:0006364","RNA binding,rRNA binding,nucleolus,rRNA processing","."]
["MRPS34","mitochondrial ribosomal protein S34 [Source:HGNC Symbol;Acc:16618]","ENSG00000074071","ENSP00000380531",".",".","family-101","MRPS34",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["UBTF","upstream binding transcription factor, RNA polymerase I [Source:HGNC Symbol;Acc:12511]","ENSG00000108312","ENSP00000302640",6,"HMG_box[3],HMG_box_5[1],HMG_box_2[2]","family-1010","UBTF",".",".","rRNA","putative rRNA","This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]","candidate mRNA binder",".",".",1,".",".",".",".","GO:0005634,GO:0005737,GO:0007566,GO:0010468,GO:0001832,GO:0005488,GO:0005515,GO:0003677,GO:0005730,GO:0005654,GO:0010467,GO:0006360,GO:0006361,GO:0006362,GO:0006363,GO:0045943,GO:0006356,GO:0000183","nucleus,cytoplasm,embryo implantation,regulation of gene expression,blastocyst growth,binding,protein binding,DNA binding,nucleolus,nucleoplasm,gene expression,transcription from RNA polymerase I promoter,transcription initiation from RNA polymerase I promoter,transcription elongation from RNA polymerase I promoter,termination of RNA polymerase I transcription,positive regulation of transcription from RNA polymerase I promoter,regulation of transcription from RNA polymerase I promoter,chromatin silencing at rDNA","."]
["CDC5L","cell division cycle 5-like [Source:HGNC Symbol;Acc:1743]","ENSG00000096401","ENSP00000360532",2,"Myb_Cef[1],Myb_DNA-bind_6[1]","family-1011","CDC5L",".",".","mRNA","mRNA","The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq, Jul 2008]","RNAbinding",".",".",1,".",".","GO:0003723,GO:0071013,GO:0000398,GO:0008380","RNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,RNA splicing","GO:0019904,GO:0003723,GO:0005515,GO:0003677,GO:0003682,GO:0071987,GO:0016607,GO:0005634,GO:0005737,GO:0005730,GO:0071013,GO:0000974,GO:0000398,GO:0008380,GO:0006351,GO:0006355,GO:0007049","protein domain specific binding,RNA binding,protein binding,DNA binding,chromatin binding,WD40-repeat domain binding,nuclear speck,nucleus,cytoplasm,nucleolus,catalytic step 2 spliceosome,Prp19 complex,mRNA splicing, via spliceosome,RNA splicing,transcription, DNA-templated,regulation of transcription, DNA-dependent,cell cycle","."]
["DAZAP1","DAZ associated protein 1 [Source:HGNC Symbol;Acc:2683]","ENSG00000071626","ENSP00000233078",2,"RRM_1[2]","family-1012","DAZAP1,MSI2,MSI1,TARDBP","DAZAP1","MSI2[28,35],MSI1[30,33],TARDBP[21,21]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0035613","RNA binding,RNA stem-loop binding","GO:0000166,GO:0003676,GO:0003723,GO:0035613,GO:0005737,GO:0005634,GO:0008283,GO:0030154,GO:0007283,GO:0001893","nucleotide binding,nucleic acid binding,RNA binding,RNA stem-loop binding,cytoplasm,nucleus,cell proliferation,cell differentiation,spermatogenesis,maternal placenta development","."]
["MSI1","musashi RNA-binding protein 1 [Source:HGNC Symbol;Acc:7330]","ENSG00000135097","ENSP00000257552",2,"RRM_1[2]","family-1012","DAZAP1,MSI2,MSI1,TARDBP","DAZAP1","MSI2[28,35],MSI1[30,33],TARDBP[21,21]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003727,GO:0003723,GO:0008266","single-stranded RNA binding,RNA binding,poly(U) RNA binding","GO:0003676,GO:0003727,GO:0000166,GO:0003723,GO:0008266,GO:0005634,GO:0005737,GO:0005844,GO:0030855,GO:0007399,GO:0009725","nucleic acid binding,single-stranded RNA binding,nucleotide binding,RNA binding,poly(U) RNA binding,nucleus,cytoplasm,polysome,epithelial cell differentiation,nervous system development,response to hormone","."]
["MSI2","musashi RNA-binding protein 2 [Source:HGNC Symbol;Acc:18585]","ENSG00000153944","ENSP00000414671",2,"RRM_1[2]","family-1012","DAZAP1,MSI2,MSI1,TARDBP","DAZAP1","MSI2[28,35],MSI1[30,33],TARDBP[21,21]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0008266,GO:0003727","poly(U) RNA binding,single-stranded RNA binding","GO:0000166,GO:0003676,GO:0008266,GO:0005737,GO:0005844,GO:0048864,GO:0003727","nucleotide binding,nucleic acid binding,poly(U) RNA binding,cytoplasm,polysome,stem cell development,single-stranded RNA binding","."]
["TARDBP","TAR DNA binding protein [Source:HGNC Symbol;Acc:11571]","ENSG00000120948","ENSP00000404666",2,"RRM_1[2]","family-1012","DAZAP1,MSI2,MSI1,TARDBP","DAZAP1","MSI2[28,35],MSI1[30,33],TARDBP[21,21]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003730,GO:0006397,GO:0008380,GO:0070935","RNA binding,mRNA 3'-UTR binding,mRNA processing,RNA splicing,3'-UTR-mediated mRNA stabilization","GO:0000166,GO:0003676,GO:0003677,GO:0005634,GO:0005515,GO:0003723,GO:0003700,GO:0003690,GO:0042802,GO:0003730,GO:0006366,GO:0006397,GO:0008380,GO:0008219,GO:0043922,GO:0070935","nucleotide binding,nucleic acid binding,DNA binding,nucleus,protein binding,RNA binding,sequence-specific DNA binding transcription factor activity,double-stranded DNA binding,identical protein binding,mRNA 3'-UTR binding,transcription from RNA polymerase II promoter,mRNA processing,RNA splicing,cell death,negative regulation by host of viral transcription,3'-UTR-mediated mRNA stabilization"," AMYOTROPHIC LATERAL SCLEROSIS 10, WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA;"]
["TRIT1","tRNA isopentenyltransferase 1 [Source:HGNC Symbol;Acc:20286]","ENSG00000043514","ENSP00000361905",2,"IPPT[1],zf-C2H2_jaz[1]","family-1013","TRIT1",".",".","tRNA","tRNA",24126054,".",".",".",".",".",".","GO:0008033,GO:0052381","tRNA processing,tRNA dimethylallyltransferase activity","GO:0005524,GO:0016740,GO:0004161,GO:0008033,GO:0009058,GO:0008270,GO:0003676,GO:0005739,GO:0046872,GO:0052381","ATP binding,transferase activity,dimethylallyltranstransferase activity,tRNA processing,biosynthetic process,zinc ion binding,nucleic acid binding,mitochondrion,metal ion binding,tRNA dimethylallyltransferase activity","."]
["MRPL36","mitochondrial ribosomal protein L36 [Source:HGNC Symbol;Acc:14490]","ENSG00000171421","ENSP00000372093",1,"Ribosomal_L36[1]","family-1014","MRPL36",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0005762,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial large ribosomal subunit,translation","GO:0005739,GO:0003735,GO:0005622,GO:0005840,GO:0005762,GO:0006412","mitochondrion,structural constituent of ribosome,intracellular,ribosome,mitochondrial large ribosomal subunit,translation","."]
["KPNB1","karyopherin (importin) beta 1 [Source:HGNC Symbol;Acc:6400]","ENSG00000108424","ENSP00000290158",2,"IBN_N[1],HEAT_EZ[1]","family-1015","KPNB1",".",".","mRNA","transport mRBP",9144189,"candidate mRNA binder",".",".",1,".",".","GO:0006610","ribosomal protein import into nucleus","GO:0005515,GO:0008565,GO:0005488,GO:0005737,GO:0031965,GO:0043234,GO:0006913,GO:0006610,GO:0008270,GO:0019904,GO:0008536,GO:0008139,GO:0005829,GO:0005654,GO:0005643,GO:0006606,GO:0006915,GO:0044281,GO:0016032,GO:0006886,GO:0019221,GO:0006309,GO:0006607,GO:0000060,GO:0019048,GO:0019058,GO:0006921,GO:0075733","protein binding,protein transporter activity,binding,cytoplasm,nuclear membrane,protein complex,nucleocytoplasmic transport,ribosomal protein import into nucleus,zinc ion binding,protein domain specific binding,Ran GTPase binding,nuclear localization sequence binding,cytosol,nucleoplasm,nuclear pore,protein import into nucleus,apoptotic process,small molecule metabolic process,viral process,intracellular protein transport,cytokine-mediated signaling pathway,apoptotic DNA fragmentation,NLS-bearing protein import into nucleus,protein import into nucleus, translocation,modulation by virus of host morphology or physiology,viral life cycle,cellular component disassembly involved in execution phase of apoptosis,intracellular transport of virus","."]
["ZNFX1","zinc finger, NFX1-type containing 1 [Source:HGNC Symbol;Acc:29271]","ENSG00000124201","ENSP00000379412",2,"AAA_11[1],AAA_12[1]","family-1016","ZNFX1",".",".","unknown","unknown","established RBP ","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0005488,GO:0003700,GO:0008270,GO:0046872,GO:0005634,GO:0006355,GO:0005524,GO:0003677,GO:0016787","binding,sequence-specific DNA binding transcription factor activity,zinc ion binding,metal ion binding,nucleus,regulation of transcription, DNA-dependent,ATP binding,DNA binding,hydrolase activity","."]
["SNRNP27","small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Source:HGNC Symbol;Acc:30240]","ENSG00000124380","ENSP00000244227",1,"DUF1777[1]","family-1017","SNRNP27",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0006397,GO:0008380","mRNA processing,RNA splicing","GO:0005515,GO:0003676,GO:0005634,GO:0006397,GO:0008380","protein binding,nucleic acid binding,nucleus,mRNA processing,RNA splicing","."]
["RBMS2","RNA binding motif, single stranded interacting protein 2 [Source:HGNC Symbol;Acc:9909]","ENSG00000076067","ENSP00000262031",2,"RRM_1[2]","family-1018","RBMS1,RBMS2,RBMS3","RBMS1","RBMS2[68,68],RBMS3[74,69]","mRNA","putative mRNA","The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0006396","nucleotide binding,nucleic acid binding,RNA binding,nucleus,RNA processing","."]
["RBMS1","RNA binding motif, single stranded interacting protein 1 [Source:HGNC Symbol;Acc:9907]","ENSG00000153250","ENSP00000387280",2,"RRM_1[2]","family-1018","RBMS1,RBMS2,RBMS3","RBMS1","RBMS2[68,68],RBMS3[74,69]","mRNA","putative mRNA","This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0005515,GO:0003690,GO:0003697,GO:0005634,GO:0006260,GO:0006396","nucleotide binding,RNA binding,nucleic acid binding,protein binding,double-stranded DNA binding,single-stranded DNA binding,nucleus,DNA replication,RNA processing","."]
["RBMS3","RNA binding motif, single stranded interacting protein 3 [Source:HGNC Symbol;Acc:13427]","ENSG00000144642","ENSP00000391934",2,"RRM_1[2]","family-1018","RBMS1,RBMS2,RBMS3","RBMS1","RBMS2[68,68],RBMS3[74,69]","mRNA","putative mRNA","This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005737,GO:0043231","nucleotide binding,RNA binding,nucleic acid binding,cytoplasm,intracellular membrane-bounded organelle","."]
["LARS2","leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:17095]","ENSG00000011376","ENSP00000412893",4,"Anticodon_1[1],tRNA-synt_1[3]","family-1019","LARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004823,GO:0006418,GO:0006429,GO:0002161","aminoacyl-tRNA ligase activity,leucine-tRNA ligase activity,tRNA aminoacylation for protein translation,leucyl-tRNA aminoacylation,aminoacyl-tRNA editing activity","GO:0000166,GO:0005524,GO:0004812,GO:0004823,GO:0005739,GO:0006418,GO:0006429,GO:0002161,GO:0005759,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,leucine-tRNA ligase activity,mitochondrion,tRNA aminoacylation for protein translation,leucyl-tRNA aminoacylation,aminoacyl-tRNA editing activity,mitochondrial matrix,gene expression"," PERRAULT SYNDROME 4; PRLTS4"]
["KIAA0020","KIAA0020 [Source:HGNC Symbol;Acc:29676]","ENSG00000080608","ENSP00000380982",1,"CPL[1]","family-102","KIAA0020",".",".","mRNA","putative mRNA","mRNA based on relationship tp PUF 21266351","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0005488,GO:0005783,GO:0005730","RNA binding,binding,endoplasmic reticulum,nucleolus","."]
["RBFOX1","RNA binding protein, fox-1 homolog (C. elegans) 1 [Source:HGNC Symbol;Acc:18222]","ENSG00000078328","ENSP00000344196",2,"Fox-1_C[1],RRM_1[1]","family-1020","RBFOX1,RBFOX2,RBFOX3","RBFOX1","RBFOX2[61,57],RBFOX3[56,75]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0043484,GO:0050658","RNA binding,mRNA processing,RNA splicing,regulation of RNA splicing,RNA transport","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0008380,GO:0043484,GO:0005515,GO:0008022,GO:0005737,GO:0005802,GO:0050885,GO:0050658","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,RNA splicing,regulation of RNA splicing,protein binding,protein C-terminus binding,cytoplasm,trans-Golgi network,neuromuscular process controlling balance,RNA transport","."]
["RBFOX2","RNA binding protein, fox-1 homolog (C. elegans) 2 [Source:HGNC Symbol;Acc:9906]","ENSG00000100320","ENSP00000352328",2,"Fox-1_C[1],RRM_1[1]","family-1020","RBFOX1,RBFOX2,RBFOX3","RBFOX1","RBFOX2[61,57],RBFOX3[56,75]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0000381,GO:0016070,GO:0006397,GO:0008380,GO:0043484","RNA binding,mRNA binding,regulation of alternative mRNA splicing, via spliceosome,RNA metabolic process,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0000166,GO:0003676,GO:0005634,GO:0005737,GO:0005515,GO:0003723,GO:0003714,GO:0003729,GO:0008134,GO:0000381,GO:0045892,GO:0016070,GO:0042127,GO:0006397,GO:0008380,GO:0050885,GO:0043484,GO:0048813,GO:0021942,GO:0030520,GO:0010724","nucleotide binding,nucleic acid binding,nucleus,cytoplasm,protein binding,RNA binding,transcription corepressor activity,mRNA binding,transcription factor binding,regulation of alternative mRNA splicing, via spliceosome,negative regulation of transcription, DNA-dependent,RNA metabolic process,regulation of cell proliferation,mRNA processing,RNA splicing,neuromuscular process controlling balance,regulation of RNA splicing,dendrite morphogenesis,radial glia guided migration of Purkinje cell,intracellular estrogen receptor signaling pathway,regulation of definitive erythrocyte differentiation","."]
["RBFOX3","RNA binding protein, fox-1 homolog (C. elegans) 3 [Source:HGNC Symbol;Acc:27097]","ENSG00000267483","ENSP00000467132",2,"Fox-1_C[1],RRM_1[1]","family-1020","RBFOX1,RBFOX2,RBFOX3","RBFOX1","RBFOX2[61,57],RBFOX3[56,75]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0000381,GO:0043484","RNA binding,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0043025,GO:0006397,GO:0008380,GO:0000381,GO:0043484,GO:0005515,GO:0005622,GO:0043204","nucleotide binding,RNA binding,nucleic acid binding,DNA binding,nucleus,cytoplasm,neuronal cell body,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of RNA splicing,protein binding,intracellular,perikaryon","."]
["CWF19L1","CWF19-like 1, cell cycle control (S. pombe) [Source:HGNC Symbol;Acc:25613]","ENSG00000095485","ENSP00000326411",3,"Metallophos_3[1],CwfJ_C_1[1],CwfJ_C_2[1]","family-1021","CWF19L1,CWF19L2","CWF19L1","CWF19L2[20,12]","mRNA","putative mRNA","by domain, 11884590",".",".",".",".",".",".",".",".","GO:0003824","catalytic activity","."]
["CWF19L2","CWF19-like 2, cell cycle control (S. pombe) [Source:HGNC Symbol;Acc:26508]","ENSG00000152404","ENSP00000282251",2,"CwfJ_C_1[1],CwfJ_C_2[1]","family-1021","CWF19L1,CWF19L2","CWF19L1","CWF19L2[20,12]","mRNA","putative mRNA","by domain, 11884590",".",".",".",".",".",".",".",".","GO:0003824","catalytic activity","."]
["ZC3H15","zinc finger CCCH-type containing 15 [Source:HGNC Symbol;Acc:29528]","ENSG00000065548","ENSP00000338788",1,"zf-CCCH[1]","family-1022","ZC3H15",".",".","unknown","unknown","by homology","candidate mRNA binder","novel",1,1,".",1,".",".","GO:0005634,GO:0005737,GO:0005515,GO:0046872,GO:0005730,GO:0019221","nucleus,cytoplasm,protein binding,metal ion binding,nucleolus,cytokine-mediated signaling pathway","."]
["LONP1","lon peptidase 1, mitochondrial [Source:HGNC Symbol;Acc:9479] [Type: protein coding Ensembl/Havana merge]","ENSG00000196365","ENSP00000353826",3,"LON[1],Lon_C[1],AAA[1]","family-1023","LONP1,LONP2","LONP1","LONP2[30,34]","diverse","RNA,DNA",14739292,".",".",".",".",".",".","GO:0003727","single-stranded RNA binding","GO:0005524,GO:0004252,GO:0004176,GO:0030163,GO:0016887,GO:0009378,GO:0006281,GO:0006310,GO:0006508,GO:0000166,GO:0043565,GO:0017111,GO:0005759,GO:0006515,GO:0034599,GO:0051131,GO:0070407,GO:0090296,GO:0003697,GO:0070361,GO:0005737,GO:0005739,GO:0001666,GO:0007568,GO:0009725,GO:0007005,GO:0010044,GO:0005515,GO:0003727,GO:0043531,GO:0051880,GO:0070182,GO:0070362,GO:0042645,GO:0043623,GO:0006200,GO:0051260,GO:0051603,GO:0000002,GO:0032042","ATP binding,serine-type endopeptidase activity,ATP-dependent peptidase activity,protein catabolic process,ATPase activity,four-way junction helicase activity,DNA repair,DNA recombination,proteolysis,nucleotide binding,sequence-specific DNA binding,nucleoside-triphosphatase activity,mitochondrial matrix,misfolded or incompletely synthesized protein catabolic process,cellular response to oxidative stress,chaperone-mediated protein complex assembly,oxidation-dependent protein catabolic process,regulation of mitochondrial DNA replication,single-stranded DNA binding,mitochondrial light strand promoter anti-sense binding,cytoplasm,mitochondrion,response to hypoxia,aging,response to hormone,mitochondrion organization,response to aluminum ion,protein binding,single-stranded RNA binding,ADP binding,G-quadruplex DNA binding,DNA polymerase binding,mitochondrial heavy strand promoter anti-sense binding,mitochondrial nucleoid,cellular protein complex assembly,ATP catabolic process,protein homooligomerization,proteolysis involved in cellular protein catabolic process,mitochondrial genome maintenance,mitochondrial DNA metabolic process","."]
["DBR1","debranching enzyme homolog 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:15594]","ENSG00000138231","ENSP00000260803",2,"Metallophos[1],DBR1[1]","family-1024","DBR1",".",".","mRNA","mRNA","The protein encoded by this gene is an RNA lariat debranching enzyme that hydrolyzes 2'-5' prime branched phosphodiester bonds. The encoded protein specifically targets the bonds at the branch point of excised lariat intron RNA, converting them to linear molecules that are then degraded. This protein may also be involved in retroviral replication. [provided by RefSeq, Nov 2011]",".","RNArelated",".",1,".",".","GO:0006397,GO:0000398,GO:0008419,GO:0000375","mRNA processing,mRNA splicing, via spliceosome,RNA lariat debranching enzyme activity,RNA splicing, via transesterification reactions","GO:0016788,GO:0006397,GO:0000398,GO:0016787,GO:0046872,GO:0008419,GO:0005634,GO:0000375","hydrolase activity, acting on ester bonds,mRNA processing,mRNA splicing, via spliceosome,hydrolase activity,metal ion binding,RNA lariat debranching enzyme activity,nucleus,RNA splicing, via transesterification reactions","."]
["RRP15","ribosomal RNA processing 15 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24255]","ENSG00000067533","ENSP00000355899",1,"Rrp15p[1]","family-1025","RRP15",".",".","rRNA","putative rRNA","This gene encodes a protein that co-purifies with human nucleoli. A similar protein in budding yeast is a component of pre-60S ribosomal particles, and is required for the early maturation steps of the 60S subunit. [provided by RefSeq, Jul 2008]Nucleolar protein; constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs (1, 2",".",".",".",".",1,".",".",".","GO:0005634,GO:0005739,GO:0005730","nucleus,mitochondrion,nucleolus","."]
["L1TD1","INE-1 type transposase domain containing 1 [Source:HGNC Symbol;Acc:25595]","ENSG00000240563","ENSP00000419901",2,"Transposase_22[2]","family-1026","L1TD1",".",".","mRNA","mRNA",22162396,".",".",".",".",1,".",".",".","GO:0003700,GO:0004871,GO:0006355,GO:0007165","sequence-specific DNA binding transcription factor activity,signal transducer activity,regulation of transcription, DNA-dependent,signal transduction","."]
["NMD3","NMD3 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24250]","ENSG00000169251","ENSP00000418908",1,"NMD3[1]","family-1027","NMD3",".",".","mRNA","mRNA","established RBP ",".","novel",".",1,1,".",".",".","GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0015031","nucleus,cytoplasm,nucleolus,nucleoplasm,protein transport","."]
["SRSF10","cDNA FLJ30749 fis, clone FEBRA2000402, highly similar to FUS-interacting serine-arginine-rich protein 1; cDNA FLJ43846 fis, clone TESTI4006393, highly similar to FUS-interacting serine-arginine-rich protein 1  [Source:UniProtKB/TrEMBL;Acc:B3KNY6]","ENSG00000215699","ENSP00000363573",1,"RRM_1[1]","family-1028","SRSF10,SRSF12,SRSF8,SRSF2,SRSF12,SRSF8,SRSF2","SRSF10","SRSF12[53,53],SRSF8[25,23],SRSF2[35,42],SRSF12[53,53],SRSF8[25,23],SRSF2[35,42]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0000398,GO:0006376,GO:0006406,GO:0048025,GO:0000375","RNA binding,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,negative regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0051082,GO:0050733,GO:0005634,GO:0005737,GO:0005654,GO:0016607,GO:0006355,GO:0000398,GO:0006376,GO:0006406,GO:0000244,GO:0048025,GO:0000375,GO:0016482","nucleotide binding,nucleic acid binding,RNA binding,protein binding,unfolded protein binding,RS domain binding,nucleus,cytoplasm,nucleoplasm,nuclear speck,regulation of transcription, DNA-dependent,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,spliceosomal tri-snRNP complex assembly,negative regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,cytoplasmic transport","."]
["SRSF12","serine/arginine-rich splicing factor 12 [Source:HGNC Symbol;Acc:21220]","ENSG00000154548","ENSP00000414302",1,"RRM_1[1]","family-1028","SRSF10,SRSF12,SRSF8,SRSF2,SRSF12,SRSF8,SRSF2","SRSF10","SRSF12[53,53],SRSF8[25,23],SRSF2[35,42],SRSF12[53,53],SRSF8[25,23],SRSF2[35,42]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0000381,GO:0048025,GO:0000395","RNA binding,regulation of alternative mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome,mRNA 5'-splice site recognition","GO:0000166,GO:0003723,GO:0003676,GO:0051082,GO:0050733,GO:0005654,GO:0000381,GO:0000244,GO:0048025,GO:0000395,GO:0016482","nucleotide binding,RNA binding,nucleic acid binding,unfolded protein binding,RS domain binding,nucleoplasm,regulation of alternative mRNA splicing, via spliceosome,spliceosomal tri-snRNP complex assembly,negative regulation of mRNA splicing, via spliceosome,mRNA 5'-splice site recognition,cytoplasmic transport","."]
["SRSF2","serine/arginine-rich splicing factor 2 [Source:HGNC Symbol;Acc:10783]","ENSG00000161547","ENSP00000463317",1,"RRM_1[1]","family-1028","SRSF10,SRSF12,SRSF8,SRSF2,SRSF12,SRSF8,SRSF2","SRSF10","SRSF12[53,53],SRSF8[25,23],SRSF2[35,42],SRSF12[53,53],SRSF8[25,23],SRSF2[35,42]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003676,GO:0003723,GO:0003714,GO:0005515,GO:0005634,GO:0005654,GO:0016607,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","nucleotide binding,nucleic acid binding,RNA binding,transcription corepressor activity,protein binding,nucleus,nucleoplasm,nuclear speck,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["SRSF8","serine/arginine-rich splicing factor 8 [Source:HGNC Symbol;Acc:16988]","ENSG00000180771","ensembl pseudogene- ncbi protein coding gene",1,"RRM_1[1]","family-1028","SRSF10,SRSF12,SRSF8,SRSF2,SRSF12,SRSF8,SRSF2","SRSF10","SRSF12[53,53],SRSF8[25,23],SRSF2[35,42],SRSF12[53,53],SRSF8[25,23],SRSF2[35,42]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,".",1,".",".",".",".","."]
["RSL1D1","ribosomal L1 domain containing 1 [Source:HGNC Symbol;Acc:24534]","ENSG00000171490","ENSP00000460343",1,"Ribosomal_L1[1]","family-1029","RSL1D1",".",".","unknown","unknown","by domain","ribosomal","RNAbinding",1,1,1,".","GO:0003723","RNA binding","GO:0003723,GO:0005730,GO:0005515,GO:0032880","RNA binding,nucleolus,protein binding,regulation of protein localization","."]
["DAP3","death associated protein 3 [Source:HGNC Symbol;Acc:2673]","ENSG00000132676","ENSP00000341692",1,"DAP3[1]","family-103","DAP3",".",".","ribosome","mitochondrial ribosome","Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]","ribosomal","RNArelated",1,1,".",".","GO:0015935,GO:0005761","small ribosomal subunit,mitochondrial ribosome","GO:0005515,GO:0005634,GO:0005739,GO:0005730,GO:0015935,GO:0005761,GO:0008637,GO:0097190,GO:0005759","protein binding,nucleus,mitochondrion,nucleolus,small ribosomal subunit,mitochondrial ribosome,apoptotic mitochondrial changes,apoptotic signaling pathway,mitochondrial matrix","."]
["NARS2","asparaginyl-tRNA synthetase 2, mitochondrial (putative) [Source:HGNC Symbol;Acc:26274]","ENSG00000137513","ENSP00000432240",2,"tRNA-synt_2[1],tRNA_anti-codon[1]","family-1030","NARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004816,GO:0006418,GO:0006421","aminoacyl-tRNA ligase activity,asparagine-tRNA ligase activity,tRNA aminoacylation for protein translation,asparaginyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0003676,GO:0004812,GO:0004816,GO:0005737,GO:0006418,GO:0006421,GO:0005739,GO:0005759,GO:0010467","nucleotide binding,ATP binding,nucleic acid binding,aminoacyl-tRNA ligase activity,asparagine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,asparaginyl-tRNA aminoacylation,mitochondrion,mitochondrial matrix,gene expression","."]
["RBM25","RNA binding motif protein 25 [Source:HGNC Symbol;Acc:23244]","ENSG00000119707","ENSP00000431150",2,"RRM_1[1],PWI[1]","family-1031","RBM25",".",".","mRNA","mRNA",18663000,"RNAbinding","experimentally validated",1,1,".",1,"GO:0003729,GO:0005681,GO:0006397,GO:0008380,GO:0000381","mRNA binding,spliceosomal complex,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","GO:0000166,GO:0005515,GO:0003676,GO:0003729,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0042981,GO:0006397,GO:0008380,GO:0000381","nucleotide binding,protein binding,nucleic acid binding,mRNA binding,nucleus,cytoplasm,spliceosomal complex,nuclear speck,regulation of apoptotic process,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","."]
["POLR2E","polymerase (RNA) II (DNA directed) polypeptide E, 25kDa [Source:HGNC Symbol;Acc:9192]","ENSG00000099817","ENSP00000215587",2,"RNA_pol_Rpb5_N[1],RNA_pol_Rpb5_C[1]","family-1032","POLR2E",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003899,GO:0005634,GO:0006351,GO:0005515,GO:0001055,GO:0001056,GO:0001054,GO:0005829,GO:0005654,GO:0005665,GO:0005736,GO:0005666,GO:0045087,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0006383,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006360,GO:0006370,GO:0032481,GO:0006283,GO:0019048,GO:0050434,GO:0006385,GO:0006386","DNA binding,DNA-directed RNA polymerase activity,nucleus,transcription, DNA-templated,protein binding,RNA polymerase II activity,RNA polymerase III activity,RNA polymerase I activity,cytosol,nucleoplasm,DNA-directed RNA polymerase II, core complex,DNA-directed RNA polymerase I complex,DNA-directed RNA polymerase III complex,innate immune response,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,transcription from RNA polymerase III promoter,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,transcription from RNA polymerase I promoter,7-methylguanosine mRNA capping,positive regulation of type I interferon production,transcription-coupled nucleotide-excision repair,modulation by virus of host morphology or physiology,positive regulation of viral transcription,transcription elongation from RNA polymerase III promoter,termination of RNA polymerase III transcription","."]
["TOE1","target of EGR1, member 1 (nuclear) [Source:HGNC Symbol;Acc:15954]","ENSG00000132773","ENSP00000361162",1,"CAF1[1]","family-1033","TOE1",".",".","unknown","unknown","by domain",".",".",".",".",".",1,".",".","GO:0003676,GO:0046872,GO:0005634,GO:0005515,GO:0005730,GO:0016607","nucleic acid binding,metal ion binding,nucleus,protein binding,nucleolus,nuclear speck","."]
["TSFM","Ts translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:12367]","ENSG00000123297","ENSP00000313877",2,"EF_TS[1],UBA[1]","family-1034","TSFM",".",".","mRNA","mRNA",22904065,"RNAbinding",".",".",1,".",".","GO:0003746,GO:0006414","translation elongation factor activity,translational elongation","GO:0003746,GO:0005634,GO:0005739,GO:0005622,GO:0006414,GO:0005515,GO:0032784","translation elongation factor activity,nucleus,mitochondrion,intracellular,translational elongation,protein binding,regulation of DNA-dependent transcription, elongation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 3; COXPD3"]
["TPR","translocated promoter region, nuclear basket protein [Source:HGNC Symbol;Acc:12017]","ENSG00000047410","ENSP00000356448",2,"TPR_MLP1_2[2]","family-1035","TPR",".",".","mRNA","mRNA","This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq, Jul 2008]",".","RNArelated",".",1,".",".","GO:0003729,GO:0004828,GO:0006434,GO:0006405,GO:0006404,GO:0031990,GO:0046832","mRNA binding,serine-tRNA ligase activity,seryl-tRNA aminoacylation,RNA export from nucleus,RNA import into nucleus,mRNA export from nucleus in response to heat stress,negative regulation of RNA export from nucleus","GO:0005515,GO:0000166,GO:0042803,GO:0005524,GO:0003682,GO:0031072,GO:0003729,GO:0004828,GO:0015631,GO:0051019,GO:0005487,GO:0070840,GO:0005635,GO:0031965,GO:0044615,GO:0034399,GO:0042405,GO:0005634,GO:0005737,GO:0019898,GO:0005654,GO:0005643,GO:0000776,GO:0072686,GO:0005868,GO:0035457,GO:0046827,GO:0000122,GO:0055085,GO:0007067,GO:0044281,GO:0000278,GO:0016032,GO:0005975,GO:0006606,GO:0019221,GO:0010827,GO:0007094,GO:0006434,GO:0015758,GO:0034605,GO:0042307,GO:0045947,GO:0007077,GO:0008645,GO:0000189,GO:0006405,GO:0006404,GO:0006999,GO:0010965,GO:0031453,GO:0031990,GO:0046832,GO:0070849,GO:0090267,GO:0090316,GO:1901673","protein binding,nucleotide binding,protein homodimerization activity,ATP binding,chromatin binding,heat shock protein binding,mRNA binding,serine-tRNA ligase activity,tubulin binding,mitogen-activated protein kinase binding,nucleocytoplasmic transporter activity,dynein complex binding,nuclear envelope,nuclear membrane,nuclear pore nuclear basket,nuclear periphery,nuclear inclusion body,nucleus,cytoplasm,extrinsic to membrane,nucleoplasm,nuclear pore,kinetochore,mitotic spindle,cytoplasmic dynein complex,cellular response to interferon-alpha,positive regulation of protein export from nucleus,negative regulation of transcription from RNA polymerase II promoter,transmembrane transport,mitosis,small molecule metabolic process,mitotic cell cycle,viral process,carbohydrate metabolic process,protein import into nucleus,cytokine-mediated signaling pathway,regulation of glucose transport,mitotic spindle assembly checkpoint,seryl-tRNA aminoacylation,glucose transport,cellular response to heat,positive regulation of protein import into nucleus,negative regulation of translational initiation,mitotic nuclear envelope disassembly,hexose transport,MAPK import into nucleus,RNA export from nucleus,RNA import into nucleus,nuclear pore organization,regulation of mitotic sister chromatid separation,positive regulation of heterochromatin assembly,mRNA export from nucleus in response to heat stress,negative regulation of RNA export from nucleus,response to epidermal growth factor,positive regulation of mitotic cell cycle spindle assembly checkpoint,positive regulation of intracellular protein transport,regulation of spindle assembly involved in mitosis"," THYROID CARCINOMA, PAPILLARY"]
["STAU1","staufen, RNA binding protein, homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:11370]","ENSG00000124214","ENSP00000360893",3,"dsrm[3]","family-1036","STAU1,STAU2","STAU1","STAU2[42,42]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0003725,GO:0010494,GO:0008298,GO:0003723,GO:0030529","double-stranded RNA binding,cytoplasmic stress granule,intracellular mRNA localization,RNA binding,ribonucleoprotein complex","GO:0005515,GO:0003725,GO:0005737,GO:0005875,GO:0010494,GO:0005791,GO:0008298,GO:0003723,GO:0008157,GO:0030529,GO:0043005,GO:0043025","protein binding,double-stranded RNA binding,cytoplasm,microtubule associated complex,cytoplasmic stress granule,rough endoplasmic reticulum,intracellular mRNA localization,RNA binding,protein phosphatase 1 binding,ribonucleoprotein complex,neuron projection,neuronal cell body","."]
["STAU2","staufen, RNA binding protein, homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:11371]","ENSG00000040341","ENSP00000429973",4,"dsrm[4]","family-1036","STAU1,STAU2","STAU1","STAU2[42,42]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",".","GO:0003725","double-stranded RNA binding","GO:0005515,GO:0003725,GO:0005783,GO:0005730,GO:0005874,GO:0006810","protein binding,double-stranded RNA binding,endoplasmic reticulum,nucleolus,microtubule,transport","."]
["TRMT1L","tRNA methyltransferase 1 homolog (S. cerevisiae)-like [Source:HGNC Symbol;Acc:16782]","ENSG00000121486","ENSP00000356476",2,"TRM[2]","family-1037","TRMT1L",".",".","tRNA","tRNA","This gene encodes a protein that has some similarity to N2,N2-dimethylguanosine tRNA methyltransferase from other organisms. Studies of the mouse ortholog have shown that this protein plays a role in motor coordination and exploratory behavior, and it may also be involved in modulating postnatal neuronal functions. Alternatively spliced transcripts have been identified for this gene. [provided by RefSeq, Jan 2011]",".","RNAbinding",".",1,".",1,"GO:0003723,GO:0000049,GO:0004809,GO:0008033","RNA binding,tRNA binding,tRNA (guanine-N2-)-methyltransferase activity,tRNA processing","GO:0003723,GO:0046872,GO:0016740,GO:0000049,GO:0004809,GO:0008033,GO:0008344,GO:0030534","RNA binding,metal ion binding,transferase activity,tRNA binding,tRNA (guanine-N2-)-methyltransferase activity,tRNA processing,adult locomotory behavior,adult behavior","."]
["METTL3","methyltransferase like 3 [Source:HGNC Symbol;Acc:17563]","ENSG00000165819","ENSP00000298717",1,"MT-A70[1]","family-1038","METTL3",".",".","mRNA","mRNA",24481042,".",".",".",".",".",".","GO:0016422,GO:0003723,GO:0006397,GO:0001510,GO:0080009","mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,RNA binding,mRNA processing,RNA methylation,mRNA methylation","GO:0008168,GO:0016422,GO:0005634,GO:0003723,GO:0005654,GO:0016607,GO:0010467,GO:0006397,GO:0007623,GO:0001510,GO:0006139,GO:0080009","methyltransferase activity,mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,nucleus,RNA binding,nucleoplasm,nuclear speck,gene expression,mRNA processing,circadian rhythm,RNA methylation,nucleobase-containing compound metabolic process,mRNA methylation","."]
["REXO2","REX2, RNA exonuclease 2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17851]","ENSG00000076043","ENSP00000442162",1,"RNase_T[1]","family-1039","REXO2",".",".","rRNA","putative rRNA","Rex2p",".",".",".",".",".",".","GO:0004527,GO:0008408","exonuclease activity,3'-5' exonuclease activity","GO:0003676,GO:0004527,GO:0005886,GO:0005739,GO:0005730,GO:0008408,GO:0005634,GO:0006139,GO:0009117","nucleic acid binding,exonuclease activity,plasma membrane,mitochondrion,nucleolus,3'-5' exonuclease activity,nucleus,nucleobase-containing compound metabolic process,nucleotide metabolic process","."]
["MRPL52","mitochondrial ribosomal protein L52 [Source:HGNC Symbol;Acc:16655]","ENSG00000172590","ENSP00000347277",".",".","family-104","MRPL52",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005762,GO:0006412,GO:0005840","structural constituent of ribosome,mitochondrial large ribosomal subunit,translation,ribosome","GO:0003735,GO:0005762,GO:0006412,GO:0005840,GO:0005739","structural constituent of ribosome,mitochondrial large ribosomal subunit,translation,ribosome,mitochondrion","."]
["WDR3","WD repeat domain 3 [Source:HGNC Symbol;Acc:12755]","ENSG00000065183","ENSP00000308179",11,"Utp12[1],WD40[10]","family-1040","WDR3",".",".","snoRNA","putative snoRNA","UTP12 yeast homolog",".","novel",".",1,1,".",".",".","GO:0005515,GO:0005634,GO:0005730,GO:0031965","protein binding,nucleus,nucleolus,nuclear membrane","."]
["CNOT11","CCR4-NOT transcription complex, subunit 11 [Source:HGNC Symbol;Acc:25217] [Type: protein coding Ensembl/Havana merge]","ENSG00000158435","ENSP00000289382",1,"DUF2363[1]","family-1041","CNOT11",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","GO:0005515,GO:0005634,GO:0005829,GO:0030014,GO:0006351,GO:0008283,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","protein binding,nucleus,cytosol,CCR4-NOT complex,transcription, DNA-templated,cell proliferation,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","."]
["YTHDC1","YTH domain-containing protein 1  [Source:UniProtKB/TrEMBL;Acc:J3KS01]","ENSG00000257413","ENSP00000447653",1,"YTH[1]","family-1042","YTHDC1",".",".","mRNA","putative mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0006397,GO:0008380","mRNA processing,RNA splicing","GO:0005515,GO:0005634,GO:0006397,GO:0008380","protein binding,nucleus,mRNA processing,RNA splicing","."]
["METTL2A","methyltransferase like 2A [Source:HGNC Symbol;Acc:25755]","ENSG00000087995","ENSP00000309610",1,"Methyltransf_23[1]","family-1043","METTL2A,METTL2B,METTL8,METTL6","METTL2A","METTL2B[98,98],METTL8[49,49],METTL6[32,43]","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0016427,GO:0030488","tRNA (cytosine) methyltransferase activity,tRNA methylation","GO:0008168,GO:0016427,GO:0008152,GO:0030488","methyltransferase activity,tRNA (cytosine) methyltransferase activity,metabolic process,tRNA methylation","."]
["METTL2B","methyltransferase like 2B [Source:HGNC Symbol;Acc:18272]","ENSG00000165055","ENSP00000262432",1,"Methyltransf_23[1]","family-1043","METTL2A,METTL2B,METTL8,METTL6","METTL2A","METTL2B[98,98],METTL8[49,49],METTL6[32,43]","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0016427,GO:0030488","tRNA (cytosine) methyltransferase activity,tRNA methylation","GO:0008168,GO:0008152,GO:0016427,GO:0030488","methyltransferase activity,metabolic process,tRNA (cytosine) methyltransferase activity,tRNA methylation","."]
["ZNF326","zinc finger protein 326 [Source:HGNC Symbol;Acc:14104]","ENSG00000162664","ENSP00000403470",1,"AKAP95[1]","family-1044","AKAP8,ZNF326,AKAP8L","AKAP8","ZNF326[21,25],AKAP8L[28,30]","mRNA","mRNA",22446626,"RNAbinding","novel",1,1,".",".","GO:0005681,GO:0044609,GO:0006397,GO:0008380","spliceosomal complex,DBIRD complex,mRNA processing,RNA splicing","GO:0005515,GO:0008270,GO:0003677,GO:0000993,GO:0005634,GO:0005681,GO:0016363,GO:0044609,GO:0006351,GO:0045893,GO:0006397,GO:0008380,GO:0032784","protein binding,zinc ion binding,DNA binding,RNA polymerase II core binding,nucleus,spliceosomal complex,nuclear matrix,DBIRD complex,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,mRNA processing,RNA splicing,regulation of DNA-dependent transcription, elongation","."]
["AKAP8","A kinase (PRKA) anchor protein 8 [Source:HGNC Symbol;Acc:378]","ENSG00000105127","ENSP00000269701",1,"AKAP95[1]","family-1044","AKAP8,ZNF326,AKAP8L","AKAP8","ZNF326[21,25],AKAP8L[28,30]","mRNA","putative mRNA","22658674, 22681889","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0008270,GO:0003677,GO:0003690,GO:0034237,GO:0005634,GO:0016363,GO:0005739,GO:0005794,GO:0000793,GO:0001939,GO:0007067,GO:0007165,GO:0007076","protein binding,zinc ion binding,DNA binding,double-stranded DNA binding,protein kinase A regulatory subunit binding,nucleus,nuclear matrix,mitochondrion,Golgi apparatus,condensed chromosome,female pronucleus,mitosis,signal transduction,mitotic chromosome condensation","."]
["AKAP8L","A kinase (PRKA) anchor protein 8-like [Source:HGNC Symbol;Acc:29857]","ENSG00000011243","ENSP00000470952",1,"AKAP95[1]","family-1044","AKAP8,ZNF326,AKAP8L","AKAP8","ZNF326[21,25],AKAP8L[28,30]","mRNA","putative mRNA","22658674, 22681889","helicase","novel",1,1,".",".","GO:0017151","DEAD/H-box RNA helicase binding","GO:0003677,GO:0005634,GO:0005515,GO:0046872,GO:0017151,GO:0005737,GO:0016363","DNA binding,nucleus,protein binding,metal ion binding,DEAD/H-box RNA helicase binding,cytoplasm,nuclear matrix","."]
["RPS14","ribosomal protein S14 [Source:HGNC Symbol;Acc:10387]","ENSG00000164587","ENSP00000428536",1,"Ribosomal_S11[1]","family-1045","RPS14",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003723,GO:0003735,GO:0045182,GO:0048027,GO:0022627,GO:0005840,GO:0000028,GO:0006412,GO:0016070,GO:0016071,GO:0006417,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0030490","RNA binding,structural constituent of ribosome,translation regulator activity,mRNA 5'-UTR binding,cytosolic small ribosomal subunit,ribosome,ribosomal small subunit assembly,translation,RNA metabolic process,mRNA metabolic process,regulation of translation,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,maturation of SSU-rRNA","GO:0003723,GO:0003735,GO:0045182,GO:0048027,GO:0005739,GO:0005829,GO:0005730,GO:0022627,GO:0005840,GO:0000122,GO:0000028,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0030218,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0030490","RNA binding,structural constituent of ribosome,translation regulator activity,mRNA 5'-UTR binding,mitochondrion,cytosol,nucleolus,cytosolic small ribosomal subunit,ribosome,negative regulation of transcription from RNA polymerase II promoter,ribosomal small subunit assembly,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,erythrocyte differentiation,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,maturation of SSU-rRNA","."]
["ELAVL1","ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [Source:HGNC Symbol;Acc:3312]","ENSG00000066044","ENSP00000472197",3,"RRM_1[3]","family-1046","ELAVL1,ELAVL2,ELAVL4,ELAVL3","ELAVL1","ELAVL2[73,67],ELAVL4[73,62],ELAVL3[70,62]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003725,GO:0003729,GO:0017091,GO:0035925,GO:0016070,GO:0016071,GO:0006417,GO:0045727,GO:0048255,GO:0070935","RNA binding,double-stranded RNA binding,mRNA binding,AU-rich element binding,mRNA 3'-UTR AU-rich region binding,RNA metabolic process,mRNA metabolic process,regulation of translation,positive regulation of translation,mRNA stabilization,3'-UTR-mediated mRNA stabilization","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003725,GO:0019901,GO:0003729,GO:0017091,GO:0035925,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0007275,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0045727,GO:0048255,GO:0070935","nucleotide binding,RNA binding,protein binding,nucleic acid binding,double-stranded RNA binding,protein kinase binding,mRNA binding,AU-rich element binding,mRNA 3'-UTR AU-rich region binding,nucleus,cytoplasm,cytosol,nucleoplasm,multicellular organismal development,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,positive regulation of translation,mRNA stabilization,3'-UTR-mediated mRNA stabilization","."]
["ELAVL2","ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) [Source:HGNC Symbol;Acc:3313]","ENSG00000107105","ENSP00000369460",3,"RRM_1[3]","family-1046","ELAVL1,ELAVL2,ELAVL4,ELAVL3","ELAVL1","ELAVL2[73,67],ELAVL4[73,62],ELAVL3[70,62]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003730","RNA binding,mRNA 3'-UTR binding","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003730,GO:0006355","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA 3'-UTR binding,regulation of transcription, DNA-dependent","."]
["ELAVL3","ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) [Source:HGNC Symbol;Acc:3314]","ENSG00000196361","ENSP00000390878",3,"RRM_1[3]","family-1046","ELAVL1,ELAVL2,ELAVL4,ELAVL3","ELAVL1","ELAVL2[73,67],ELAVL4[73,62],ELAVL3[70,62]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,"GO:0003723,GO:0017091","RNA binding,AU-rich element binding","GO:0000166,GO:0003676,GO:0003723,GO:0017091,GO:0030154,GO:0007399","nucleotide binding,nucleic acid binding,RNA binding,AU-rich element binding,cell differentiation,nervous system development","."]
["ELAVL4","ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 [Source:HGNC Symbol;Acc:3315]","ENSG00000162374","ENSP00000399939",3,"RRM_1[3]","family-1046","ELAVL1,ELAVL2,ELAVL4,ELAVL3","ELAVL1","ELAVL2[73,67],ELAVL4[73,62],ELAVL3[70,62]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,"GO:0003723,GO:0003730,GO:0017091,GO:0006397,GO:0006396","RNA binding,mRNA 3'-UTR binding,AU-rich element binding,mRNA processing,RNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0003730,GO:0017091,GO:0006397,GO:0006396","nucleotide binding,RNA binding,nucleic acid binding,mRNA 3'-UTR binding,AU-rich element binding,mRNA processing,RNA processing","."]
["PNN","pinin, desmosome associated protein [Source:HGNC Symbol;Acc:9162]","ENSG00000100941","ENSP00000216832",2,"Pinin_SDK_N[1],Pinin_SDK_memA[1]","family-1047","PNN",".",".","mRNA","putative mRNA",12051732,"candidate mRNA binder","RNArelated",1,1,".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005198,GO:0003677,GO:0005634,GO:0005886,GO:0005737,GO:0005882,GO:0005911,GO:0016607,GO:0030057,GO:0035145,GO:0071013,GO:0006351,GO:0006355,GO:0007155,GO:0000398","structural molecule activity,DNA binding,nucleus,plasma membrane,cytoplasm,intermediate filament,cell-cell junction,nuclear speck,desmosome,exon-exon junction complex,catalytic step 2 spliceosome,transcription, DNA-templated,regulation of transcription, DNA-dependent,cell adhesion,mRNA splicing, via spliceosome","."]
["DDX41","DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 [Source:HGNC Symbol;Acc:18674]","ENSG00000183258","ENSP00000330349",2,"Helicase_C[1],DEAD[1]","family-1048","DDX41",".",".","mRNA","mRNA","by homology","helicase","RNAbinding",1,1,".",".","GO:0003723,GO:0071013,GO:0000398,GO:0006396","RNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,RNA processing","GO:0005634,GO:0005524,GO:0003676,GO:0008026,GO:0005515,GO:0003723,GO:0008270,GO:0003677,GO:0004386,GO:0005829,GO:0005783,GO:0071013,GO:0045944,GO:0045087,GO:0006915,GO:0007275,GO:0000398,GO:0006396,GO:0035458,GO:0051607,GO:0032481,GO:0032479","nucleus,ATP binding,nucleic acid binding,ATP-dependent helicase activity,protein binding,RNA binding,zinc ion binding,DNA binding,helicase activity,cytosol,endoplasmic reticulum,catalytic step 2 spliceosome,positive regulation of transcription from RNA polymerase II promoter,innate immune response,apoptotic process,multicellular organismal development,mRNA splicing, via spliceosome,RNA processing,cellular response to interferon-beta,defense response to virus,positive regulation of type I interferon production,regulation of type I interferon production","."]
["TNPO2","transportin 2 [Source:HGNC Symbol;Acc:19998]","ENSG00000105576","ENSP00000397379",5,"IBN_N[1],HEAT_2[1],Arm[1],HEAT_EZ[1],HEAT[1]","family-1049","TNPO1,TNPO2","TNPO1","TNPO2[84,84]","mRNA","putative mRNA",9298975,".",".",".",".",".",".",".",".","GO:0005488,GO:0005515,GO:0008536,GO:0008139,GO:0005634,GO:0005737,GO:0006886","binding,protein binding,Ran GTPase binding,nuclear localization sequence binding,nucleus,cytoplasm,intracellular protein transport","."]
["TNPO1","transportin 1 [Source:HGNC Symbol;Acc:6401]","ENSG00000083312","ENSP00000336712",4,"IBN_N[1],HEAT_2[1],HEAT_EZ[1],HEAT[1]","family-1049","TNPO1,TNPO2","TNPO1","TNPO2[84,84]","mRNA","mRBP transport",19124606,"candidate mRNA binder","RNArelated",1,1,1,".","GO:0016070,GO:0016071","RNA metabolic process,mRNA metabolic process","GO:0005488,GO:0008536,GO:0005634,GO:0006886,GO:0005515,GO:0008139,GO:0005737,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0000060,GO:0019048","binding,Ran GTPase binding,nucleus,intracellular protein transport,protein binding,nuclear localization sequence binding,cytoplasm,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,protein import into nucleus, translocation,modulation by virus of host morphology or physiology","."]
["PUSL1","pseudouridylate synthase-like 1 [Source:HGNC Symbol;Acc:26914]","ENSG00000169972","ENSP00000368318",2,"PseudoU_synth_1[2]","family-105","PUSL1",".",".","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0008033,GO:0009451","RNA binding,tRNA processing,RNA modification","GO:0003723,GO:0009982,GO:0008033,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,tRNA processing,pseudouridine synthesis,RNA modification","."]
["RBM43","RNA binding motif protein 43 [Source:HGNC Symbol;Acc:24790]","ENSG00000184898","ENSP00000331211",1,"RRM_6[1]","family-1050","RBM43",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["ZGPAT","zinc finger, CCCH-type with G patch domain [Source:HGNC Symbol;Acc:15948]","ENSG00000197114","ENSP00000332013",3,"G-patch[1],Laminin_I[1],zf-CCCH[1]","family-1051","ZGPAT",".",".","unknown","unknown","by domain",".",".",".",".",".",1,".",".","GO:0003700,GO:0005515,GO:0003676,GO:0046872,GO:0043565,GO:0005634,GO:0006351,GO:0045892,GO:0007175","sequence-specific DNA binding transcription factor activity,protein binding,nucleic acid binding,metal ion binding,sequence-specific DNA binding,nucleus,transcription, DNA-templated,negative regulation of transcription, DNA-dependent,negative regulation of epidermal growth factor-activated receptor activity","."]
["SCAF11","SR-related CTD-associated factor 11 [Source:HGNC Symbol;Acc:10784]","ENSG00000139218","ENSP00000358374",1,"zf-RING_2[1]","family-1052","SCAF11",".",".","mRNA","mRNA",9447963,"candidate mRNA binder","RNArelated",1,1,".",".","GO:0006397,GO:0008380,GO:0000245,GO:0000375","mRNA processing,RNA splicing,spliceosomal complex assembly,RNA splicing, via transesterification reactions","GO:0005515,GO:0008270,GO:0005634,GO:0006397,GO:0008380,GO:0000245,GO:0000375,GO:0046872","protein binding,zinc ion binding,nucleus,mRNA processing,RNA splicing,spliceosomal complex assembly,RNA splicing, via transesterification reactions,metal ion binding","."]
["USP39","ubiquitin specific peptidase 39 [Source:HGNC Symbol;Acc:20071]","ENSG00000168883","ENSP00000312981",2,"UCH[1],zf-UBP[1]","family-1053","USP39",".",".","snRNA","putative snRNA",11350945,".",".",".",".",".",".","GO:0005681,GO:0006397,GO:0008380,GO:0000245","spliceosomal complex,mRNA processing,RNA splicing,spliceosomal complex assembly","GO:0008270,GO:0004221,GO:0005681,GO:0006511,GO:0051301,GO:0007049,GO:0006397,GO:0008380,GO:0000245","zinc ion binding,ubiquitin thiolesterase activity,spliceosomal complex,ubiquitin-dependent protein catabolic process,cell division,cell cycle,mRNA processing,RNA splicing,spliceosomal complex assembly","."]
["RPL38","ribosomal protein L38 [Source:HGNC Symbol;Acc:10349]","ENSG00000172809","ENSP00000462580",1,"Ribosomal_L38e[1]","family-1054","RPL38",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0033291,GO:0006412,GO:0016070,GO:0016071,GO:0006417,GO:0006414,GO:0034463,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,eukaryotic 80S initiation complex,translation,RNA metabolic process,mRNA metabolic process,regulation of translation,translational elongation,90S preribosome assembly,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0033291,GO:0001501,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0007605,GO:0042474,GO:0001503,GO:0044267,GO:0006614,GO:0006414,GO:0034463,GO:0048318,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,eukaryotic 80S initiation complex,skeletal system development,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,sensory perception of sound,middle ear morphogenesis,ossification,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,90S preribosome assembly,axial mesoderm development,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["NARS","asparaginyl-tRNA synthetase [Source:HGNC Symbol;Acc:7643]","ENSG00000134440","ENSP00000256854",2,"tRNA-synt_2[1],tRNA_anti-codon[1]","family-1055","NARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004816,GO:0006418,GO:0006421","aminoacyl-tRNA ligase activity,asparagine-tRNA ligase activity,tRNA aminoacylation for protein translation,asparaginyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004816,GO:0005737,GO:0006418,GO:0006421,GO:0003676,GO:0005739,GO:0005829,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,asparagine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,asparaginyl-tRNA aminoacylation,nucleic acid binding,mitochondrion,cytosol,gene expression","."]
["RPS16","ribosomal protein S16 [Source:HGNC Symbol;Acc:10396]","ENSG00000105193","ENSP00000251453",1,"Ribosomal_S9[1]","family-1056","RPS16",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022627,GO:0015935,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic small ribosomal subunit,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022627,GO:0005829,GO:0015935,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic small ribosomal subunit,cytosol,small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis","."]
["CLASRP","CLK4-associating serine/arginine rich protein [Source:HGNC Symbol;Acc:17731]","ENSG00000104859","ENSP00000465562",1,"DRY_EERY[1]","family-1057","CLASRP",".",".","mRNA","mRNA",12169693,".",".",".",".",".",1,"GO:0006397,GO:0008380","mRNA processing,RNA splicing","GO:0005634,GO:0006397,GO:0008380","nucleus,mRNA processing,RNA splicing","."]
["RPS9","ribosomal protein S9 [Source:HGNC Symbol;Acc:10442]","ENSG00000170889","ENSP00000302896",2,"Ribosomal_S4[1],S4[1]","family-1058","RPS9",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,".",".","GO:0003723,GO:0003735,GO:0019843,GO:0045182,GO:0022627,GO:0005840,GO:0030529,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006417,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,rRNA binding,translation regulator activity,cytosolic small ribosomal subunit,ribosome,ribonucleoprotein complex,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,regulation of translation,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0019843,GO:0045182,GO:0005737,GO:0005829,GO:0005622,GO:0005730,GO:0022627,GO:0005840,GO:0030529,GO:0015935,GO:0006412,GO:0008284,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,rRNA binding,translation regulator activity,cytoplasm,cytosol,intracellular,nucleolus,cytosolic small ribosomal subunit,ribosome,ribonucleoprotein complex,small ribosomal subunit,translation,positive regulation of cell proliferation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["TOP3B","topoisomerase (DNA) III beta [Source:HGNC Symbol;Acc:11993]","ENSG00000100038","ENSP00000349705",2,"Topoisom_bac[1],Toprim[1]","family-1059","TOP3A,TOP3B","TOP3A","TOP3B[28,33]","mRNA","mRNA",23912948,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0003677,GO:0003917,GO:0003916,GO:0005694,GO:0006265,GO:0000793,GO:0007059,GO:0005524,GO:0005634","DNA binding,DNA topoisomerase type I activity,DNA topoisomerase activity,chromosome,DNA topological change,condensed chromosome,chromosome segregation,ATP binding,nucleus","."]
["NCBP2L","nuclear cap binding protein subunit 2-like [Source:HGNC Symbol;Acc:31795]","ENSG00000170935","ENSP00000361454",1,"RRM_1[1]","family-106","NCBP2,NCBP2L","NCBP2","NCBP2L[63,64]","mRNA","mRNA","by homology",".",".",".",".",".",1,"GO:0000339,GO:0045292","RNA cap binding,mRNA cis splicing, via spliceosome","GO:0000166,GO:0003676,GO:0000339,GO:0005846,GO:0045292","nucleotide binding,nucleic acid binding,RNA cap binding,nuclear cap binding complex,mRNA cis splicing, via spliceosome","."]
["NCBP2","nuclear cap binding protein subunit 2, 20kDa [Source:HGNC Symbol;Acc:7659]","ENSG00000114503","ENSP00000389315",1,"RRM_5[1]","family-106","NCBP2,NCBP2L","NCBP2","NCBP2L[63,64]","mRNA","mRNA","The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,".",".","GO:0000339,GO:0045292,GO:0000340,GO:0005845,GO:0016070,GO:0016071,GO:0031047,GO:0008380,GO:0000398,GO:0006446,GO:0006370,GO:0006406,GO:0031124,GO:0000387,GO:0034660,GO:0000184,GO:0008334,GO:0006408,GO:0046833","RNA cap binding,mRNA cis splicing, via spliceosome,RNA 7-methylguanosine cap binding,mRNA cap binding complex,RNA metabolic process,mRNA metabolic process,gene silencing by RNA,RNA splicing,mRNA splicing, via spliceosome,regulation of translational initiation,7-methylguanosine mRNA capping,mRNA export from nucleus,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,histone mRNA metabolic process,snRNA export from nucleus,positive regulation of RNA export from nucleus","GO:0000166,GO:0003676,GO:0000339,GO:0005846,GO:0045292,GO:0005515,GO:0000340,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005845,GO:0006366,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0031047,GO:0008380,GO:0000398,GO:0006446,GO:0006368,GO:0006370,GO:0006406,GO:0031124,GO:0000387,GO:0050434,GO:0034660,GO:0000184,GO:0006369,GO:0008334,GO:0006408,GO:0046833","nucleotide binding,nucleic acid binding,RNA cap binding,nuclear cap binding complex,mRNA cis splicing, via spliceosome,protein binding,RNA 7-methylguanosine cap binding,nucleus,cytoplasm,cytosol,nucleoplasm,mRNA cap binding complex,transcription from RNA polymerase II promoter,viral process,gene expression,RNA metabolic process,mRNA metabolic process,gene silencing by RNA,RNA splicing,mRNA splicing, via spliceosome,regulation of translational initiation,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,mRNA export from nucleus,mRNA 3'-end processing,spliceosomal snRNP assembly,positive regulation of viral transcription,ncRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription,histone mRNA metabolic process,snRNA export from nucleus,positive regulation of RNA export from nucleus","."]
["SMG9","smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:25763]","ENSG00000105771","ENSP00000270066",1,"DUF2146[1]","family-1060","SMG9",".",".","mRNA","mRNA",19417104,".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0000184","RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0042802,GO:0005829,GO:0005622,GO:0010467,GO:0016070,GO:0016071,GO:0000184","protein binding,identical protein binding,cytosol,intracellular,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["FTSJ2","FtsJ RNA methyltransferase homolog 2 (E. coli) [Source:HGNC Symbol;Acc:16352]","ENSG00000122687","ENSP00000392343",1,"FtsJ[1]","family-1061","FTSJ2",".",".","rRNA","putative rRNA","MRM2 yeast homolog",".",".",".",".",".",".","GO:0001510,GO:0008650,GO:0006364,GO:0031167","RNA methylation,rRNA (uridine-2'-O-)-methyltransferase activity,rRNA processing,rRNA methylation","GO:0008168,GO:0001510,GO:0032259,GO:0008650,GO:0005739,GO:0005730,GO:0008283,GO:0006364,GO:0031167","methyltransferase activity,RNA methylation,methylation,rRNA (uridine-2'-O-)-methyltransferase activity,mitochondrion,nucleolus,cell proliferation,rRNA processing,rRNA methylation","."]
["DDX56","DEAD (Asp-Glu-Ala-Asp) box helicase 56 [Source:HGNC Symbol;Acc:18193]","ENSG00000136271","ENSP00000258772",3,"Helicase_C[2],DEAD[1]","family-1062","DDX56",".",".","rRNA","rRNA","yeast homolog DBP9",".","RNAbinding",".",1,1,".","GO:0003723,GO:0004004,GO:0006364","RNA binding,ATP-dependent RNA helicase activity,rRNA processing","GO:0005524,GO:0003676,GO:0008026,GO:0003723,GO:0003677,GO:0016787,GO:0004386,GO:0004004,GO:0005730,GO:0006364","ATP binding,nucleic acid binding,ATP-dependent helicase activity,RNA binding,DNA binding,hydrolase activity,helicase activity,ATP-dependent RNA helicase activity,nucleolus,rRNA processing","."]
["RBM28","RNA binding motif protein 28 [Source:HGNC Symbol;Acc:21863]","ENSG00000106344","ENSP00000223073",4,"RRM_1[3],RRM_6[1]","family-1063","RBM28",".",".","snRNA","snRNA/mRNA","The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380","RNA binding,spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005730,GO:0005794,GO:0005681,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,RNA binding,nucleolus,Golgi apparatus,spliceosomal complex,mRNA processing,RNA splicing"," ALOPECIA, NEUROLOGIC DEFECTS, AND ENDOCRINOPATHY SYNDROME"]
["UTP11L","UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast) [Source:HGNC Symbol;Acc:24329]","ENSG00000183520","ENSP00000362105",1,"Utp11[1]","family-1064","UTP11L",".",".","snoRNA","snoRNA/rRNA","established RBP ","RNAbinding","RNArelated",1,1,".",".","GO:0006364,GO:0042274","rRNA processing,ribosomal small subunit biogenesis","GO:0032040,GO:0006364,GO:0005515,GO:0005737,GO:0005615,GO:0005730,GO:0043065,GO:0007399,GO:0042274","small-subunit processome,rRNA processing,protein binding,cytoplasm,extracellular space,nucleolus,positive regulation of apoptotic process,nervous system development,ribosomal small subunit biogenesis","."]
["MRPS18B","mitochondrial ribosomal protein S18B [Source:HGNC Symbol;Acc:14516]","ENSG00000223775","ENSP00000402718",1,"Ribosomal_S18[1]","family-1065","MRPS18B",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005622,GO:0005840,GO:0005763,GO:0006412,GO:0005739","structural constituent of ribosome,intracellular,ribosome,mitochondrial small ribosomal subunit,translation,mitochondrion","."]
["RPL14","ribosomal protein L14 [Source:HGNC Symbol;Acc:10305]","ENSG00000188846","ENSP00000379506",2,"KOW[1],Ribosomal_L14e[1]","family-1066","RPL14",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005515,GO:0005737,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,protein binding,cytoplasm,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL37","ribosomal protein L37 [Source:HGNC Symbol;Acc:10347]","ENSG00000145592","ENSP00000422823",1,"Ribosomal_L37e[1]","family-1067","RPL37",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0019843,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,rRNA binding,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0046872,GO:0003735,GO:0019843,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","metal ion binding,structural constituent of ribosome,rRNA binding,intracellular,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["GEMIN5","gem (nuclear organelle) associated protein 5 [Source:HGNC Symbol;Acc:20043]","ENSG00000082516","ENSP00000285873",4,"WD40[4]","family-1068","GEMIN5",".",".","snRNA","snRNA","established RBP ",".","experimentally validated",".",1,".",".","GO:0017069,GO:0005681,GO:0016070,GO:0000398,GO:0000387,GO:0034660","snRNA binding,spliceosomal complex,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005515,GO:0017069,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005681,GO:0016604,GO:0097504,GO:0010467,GO:0016070,GO:0000398,GO:0006461,GO:0000387,GO:0034660","protein binding,snRNA binding,nucleus,cytoplasm,cytosol,nucleoplasm,spliceosomal complex,nuclear body,Gemini of coiled bodies,gene expression,RNA metabolic process,mRNA splicing, via spliceosome,protein complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["MKRN1","makorin ring finger protein 1 [Source:HGNC Symbol;Acc:7112]","ENSG00000133606","ENSP00000416369",4,"zf-C3HC4[1],zf-CCCH[3]","family-1069","MKRN1,MKRN3,MKRN2","MKRN1","MKRN3[51,49],MKRN2[39,45]","mRNA","mRNA",22128154,".","novel",".",1,".",1,".",".","GO:0005515,GO:0008270,GO:0046872,GO:0003682,GO:0016874,GO:0016567","protein binding,zinc ion binding,metal ion binding,chromatin binding,ligase activity,protein ubiquitination","."]
["MKRN2","makorin ring finger protein 2 [Source:HGNC Symbol;Acc:7113]","ENSG00000075975","ENSP00000170447",5,"zf-RING_2[1],zf-CCCH[4]","family-1069","MKRN1,MKRN3,MKRN2","MKRN1","MKRN3[51,49],MKRN2[39,45]","mRNA","putative mRNA","by homology","RNAbinding",".",".",1,".",1,".",".","GO:0005515,GO:0008270,GO:0046872,GO:0016874,GO:0005622,GO:0016567","protein binding,zinc ion binding,metal ion binding,ligase activity,intracellular,protein ubiquitination","."]
["MKRN3","makorin ring finger protein 3 [Source:HGNC Symbol;Acc:7114]","ENSG00000179455","ENSP00000313881",2,"zf-C3HC4[1],zf-CCCH[1]","family-1069","MKRN1,MKRN3,MKRN2","MKRN1","MKRN3[51,49],MKRN2[39,45]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0030529","ribonucleoprotein complex","GO:0005515,GO:0008270,GO:0016874,GO:0046872,GO:0030529,GO:0016567","protein binding,zinc ion binding,ligase activity,metal ion binding,ribonucleoprotein complex,protein ubiquitination"," PRECOCIOUS PUBERTY, CENTRAL, 2; CPPB2"]
["NOA1","nitric oxide associated 1 [Source:HGNC Symbol;Acc:28473]","ENSG00000084092","ENSP00000264230",1,"MMR_HSR1[1]","family-107","NOA1",".",".","rRNA","rRNA",22447445,".","novel",".",1,1,".","GO:0032543,GO:0042254","mitochondrial translation,ribosome biogenesis","GO:0005515,GO:0005525,GO:0003924,GO:0005739,GO:0005743,GO:0031314,GO:0043457,GO:0010941,GO:0032543,GO:0006915,GO:0042254,GO:0006184","protein binding,GTP binding,GTPase activity,mitochondrion,mitochondrial inner membrane,extrinsic to mitochondrial inner membrane,regulation of cellular respiration,regulation of cell death,mitochondrial translation,apoptotic process,ribosome biogenesis,GTP catabolic process","."]
["PINX1","PIN2/TERF1 interacting, telomerase inhibitor 1 [Source:HGNC Symbol;Acc:30046]","ENSG00000254093","ENSP00000318966",1,"G-patch[1]","family-1070","PINX1",".",".","ncRNA","teloRNA",21119197,".",".",".",".",".",".","GO:0070034","telomeric RNA binding","GO:0003676,GO:0005634,GO:0005737,GO:0005739,GO:0043231,GO:0005730,GO:0005515,GO:0070034,GO:0010521,GO:0005819,GO:0000777,GO:0000781,GO:0000776,GO:0000228,GO:0008285,GO:0007080,GO:0051974,GO:0007004,GO:0051972","nucleic acid binding,nucleus,cytoplasm,mitochondrion,intracellular membrane-bounded organelle,nucleolus,protein binding,telomeric RNA binding,telomerase inhibitor activity,spindle,condensed chromosome kinetochore,chromosome, telomeric region,kinetochore,nuclear chromosome,negative regulation of cell proliferation,mitotic metaphase plate congression,negative regulation of telomerase activity,telomere maintenance via telomerase,regulation of telomerase activity","."]
["HRSP12","heat-responsive protein 12 [Source:HGNC Symbol;Acc:16897]","ENSG00000132541","ENSP00000428596",1,"Ribonuc_L-PSP[1]","family-1071","HRSP12",".",".","unknown","unknown",8530410,".","novel",".",1,".",".","GO:0006449","regulation of translational termination","GO:0019239,GO:0004519,GO:0005634,GO:0005737,GO:0005739,GO:0006449","deaminase activity,endonuclease activity,nucleus,cytoplasm,mitochondrion,regulation of translational termination","."]
["TDRD9","tudor domain containing 9 [Source:HGNC Symbol;Acc:20122]","ENSG00000156414","ENSP00000343545",4,"TUDOR[1],HA2[1],Helicase_C[1],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","ncRNA","piRNA related",20059948,".",".",".",".",".",".","GO:0071547,GO:0031047,GO:0034587","piP-body,gene silencing by RNA,piRNA metabolic process","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634,GO:0071547,GO:0030154,GO:0007275,GO:0007283,GO:0007140,GO:0009566,GO:0031047,GO:0034587,GO:0043046,GO:0005515","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus,piP-body,cell differentiation,multicellular organismal development,spermatogenesis,male meiosis,fertilization,gene silencing by RNA,piRNA metabolic process,DNA methylation involved in gamete generation,protein binding","."]
["DHX30","DEAH (Asp-Glu-Ala-His) box polypeptide 30 [Source:HGNC Symbol;Acc:16716]","ENSG00000132153","ENSP00000343442",5,"OB_NTP_bind[1],HA2[1],Helicase_C[1],dsrm[1],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","mRNA","mRNA",21204022,"helicase","RNAbinding",1,1,".",".","GO:0003725","double-stranded RNA binding","GO:0005515,GO:0005524,GO:0003676,GO:0003725,GO:0008026,GO:0003682,GO:0004386,GO:0005737,GO:0005739,GO:0042645","protein binding,ATP binding,nucleic acid binding,double-stranded RNA binding,ATP-dependent helicase activity,chromatin binding,helicase activity,cytoplasm,mitochondrion,mitochondrial nucleoid","."]
["DHX29","DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Source:HGNC Symbol;Acc:15815]","ENSG00000067248","ENSP00000251636",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","mRNA","mRNA",23047696,"helicase",".",".",1,".",".","GO:0003743,GO:0043024,GO:0016282","translation initiation factor activity,ribosomal small subunit binding,eukaryotic 43S preinitiation complex","GO:0005524,GO:0003676,GO:0008026,GO:0003743,GO:0004386,GO:0043024,GO:0005739,GO:0016282","ATP binding,nucleic acid binding,ATP-dependent helicase activity,translation initiation factor activity,helicase activity,ribosomal small subunit binding,mitochondrion,eukaryotic 43S preinitiation complex","."]
["DHX57","DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Source:HGNC Symbol;Acc:20086]","ENSG00000163214","ENSP00000295373",5,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1],RWD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","mRNA","mRNA","by homology","helicase","novel",1,1,".",1,".",".","GO:0005515,GO:0046872,GO:0005524,GO:0003676,GO:0004386,GO:0008026","protein binding,metal ion binding,ATP binding,nucleic acid binding,helicase activity,ATP-dependent helicase activity","."]
["YTHDC2","YTH domain containing 2 [Source:HGNC Symbol;Acc:24721]","ENSG00000047188","ENSP00000161863",7,"OB_NTP_bind[1],Ank_2[1],HA2[1],Helicase_C[1],YTH[1],R3H[1],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","mRNA","mRNA","established RBP ","helicase","novel",1,1,".",1,".",".","GO:0003676,GO:0005515,GO:0005524,GO:0008026,GO:0004386","nucleic acid binding,protein binding,ATP binding,ATP-dependent helicase activity,helicase activity","."]
["DHX36","DEAH (Asp-Glu-Ala-His) box polypeptide 36 [Source:HGNC Symbol;Acc:14410]","ENSG00000174953","ENSP00000417078",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","mRNA","mRNA","The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","helicase","novel",1,1,".",".","GO:0003725,GO:0043330","double-stranded RNA binding,response to exogenous dsRNA","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634,GO:0005737,GO:0003725,GO:0009615,GO:0043330,GO:0005515,GO:0005829,GO:0045087,GO:0032481","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus,cytoplasm,double-stranded RNA binding,response to virus,response to exogenous dsRNA,protein binding,cytosol,innate immune response,positive regulation of type I interferon production","."]
["DHX9","DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Source:HGNC Symbol;Acc:2750]","ENSG00000135829","ENSP00000356520",6,"OB_NTP_bind[1],HA2[1],Helicase_C[1],dsrm[2],DEAD[1]","family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","DHX36","DHX30[29,25],YTHDC2[34,24],DHX9[31,24],DHX29[35,26],DHX57[42,30],TDRD9[24,18]","ncRNA","viral RNA","This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010]","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003724,GO:0004004,GO:0030529,GO:0070937,GO:0008380,GO:0000398,GO:0070934","RNA binding,RNA helicase activity,ATP-dependent RNA helicase activity,ribonucleoprotein complex,CRD-mediated mRNA stability complex,RNA splicing,mRNA splicing, via spliceosome,CRD-mediated mRNA stabilization","GO:0005515,GO:0003723,GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0004003,GO:0004386,GO:0001085,GO:0003724,GO:0004004,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0005654,GO:0005813,GO:0030529,GO:0070937,GO:0045087,GO:0010467,GO:0008380,GO:0000398,GO:0007623,GO:0034605,GO:0032481,GO:0070934","protein binding,RNA binding,ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,ATP-dependent DNA helicase activity,helicase activity,RNA polymerase II transcription factor binding,RNA helicase activity,ATP-dependent RNA helicase activity,nucleus,cytoplasm,cytosol,nucleolus,nucleoplasm,centrosome,ribonucleoprotein complex,CRD-mediated mRNA stability complex,innate immune response,gene expression,RNA splicing,mRNA splicing, via spliceosome,circadian rhythm,cellular response to heat,positive regulation of type I interferon production,CRD-mediated mRNA stabilization","."]
["EIF3G","eukaryotic translation initiation factor 3, subunit G [Source:HGNC Symbol;Acc:3274]","ENSG00000130811","ENSP00000466860",2,"RRM_1[1],eIF3g[1]","family-1073","EIF3G",".",".","mRNA","mRNA",16766523,"translationfactor","RNAbinding",1,1,1,1,"GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0006413,GO:0006412,GO:0001731,GO:0006446","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translational initiation,translation,formation of translation preinitiation complex,regulation of translational initiation","GO:0003743,GO:0005852,GO:0005737,GO:0000166,GO:0003676,GO:0005515,GO:0005634,GO:0005829,GO:0048471,GO:0016282,GO:0033290,GO:0006413,GO:0006412,GO:0010467,GO:0001731,GO:0006446,GO:0044267","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,cytoplasm,nucleotide binding,nucleic acid binding,protein binding,nucleus,cytosol,perinuclear region of cytoplasm,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translational initiation,translation,gene expression,formation of translation preinitiation complex,regulation of translational initiation,cellular protein metabolic process","."]
["NOL10","nucleolar protein 10 [Source:HGNC Symbol;Acc:25862]","ENSG00000115761","ENSP00000263837",1,"NUC153[1]","family-1074","NOL10",".",".","rRNA","putative rRNA","ENP2 yeast homolog","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005634,GO:0005730","protein binding,nucleus,nucleolus","."]
["UTP15","UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25758]","ENSG00000164338","ENSP00000421669",4,"UTP15_C[1],WD40[3]","family-1075","UTP15",".",".","snoRNA","snoRNA/rRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0006364","rRNA processing","GO:0005515,GO:0005730,GO:0006364,GO:0005737","protein binding,nucleolus,rRNA processing,cytoplasm","."]
["GATC","glutamyl-tRNA(Gln) amidotransferase, subunit C [Source:HGNC Symbol;Acc:25068]","ENSG00000257218","ENSP00000446872",1,"Glu-tRNAGln[1]","family-1076","GATC",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0006450,GO:0050567,GO:0030956,GO:0032543","regulation of translational fidelity,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,glutamyl-tRNA(Gln) amidotransferase complex,mitochondrial translation","GO:0006450,GO:0005524,GO:0050567,GO:0005739,GO:0030956,GO:0032543,GO:0070681","regulation of translational fidelity,ATP binding,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,mitochondrion,glutamyl-tRNA(Gln) amidotransferase complex,mitochondrial translation,glutaminyl-tRNAGln biosynthesis via transamidation","."]
["TCOF1","Treacher Collins-Franceschetti syndrome 1 [Source:HGNC Symbol;Acc:11654]","ENSG00000070814","ENSP00000409944",3,"Treacle[3]","family-1077","TCOF1",".",".","rRNA","putative rRNA",15930015,"candidate mRNA binder","RNArelated",1,1,1,".",".",".","GO:0005515,GO:0005215,GO:0005634,GO:0005737,GO:0005730,GO:0001501,GO:0042790","protein binding,transporter activity,nucleus,cytoplasm,nucleolus,skeletal system development,transcription of nuclear large rRNA transcript from RNA polymerase I promoter"," TREACHER COLLINS SYNDROME 1; TCS1"]
["NONO","non-POU domain containing, octamer-binding [Source:HGNC Symbol;Acc:7871]","ENSG00000147140","ENSP00000441364",3,"RRM_1[2],NOPS[1]","family-1078","NONO,PSPC1,SFPQ","NONO","PSPC1[60,54],SFPQ[59,39]","ncRNA","lincRNA/mRNA",19217333,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003677,GO:0042802,GO:0005634,GO:0005730,GO:0016363,GO:0016607,GO:0042382,GO:0006351,GO:0006355,GO:0006281,GO:0006310,GO:0006397,GO:0008380","nucleotide binding,RNA binding,protein binding,nucleic acid binding,DNA binding,identical protein binding,nucleus,nucleolus,nuclear matrix,nuclear speck,paraspeckles,transcription, DNA-templated,regulation of transcription, DNA-dependent,DNA repair,DNA recombination,mRNA processing,RNA splicing","."]
["PSPC1","paraspeckle component 1 [Source:HGNC Symbol;Acc:20320]","ENSG00000121390","ENSP00000393069",3,"RRM_1[2],NOPS[1]","family-1078","NONO,PSPC1,SFPQ","NONO","PSPC1[60,54],SFPQ[59,39]","ncRNA","lincRNA",22102035,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003676,GO:0005515,GO:0000166,GO:0003723,GO:0005654,GO:0005634,GO:0005737,GO:0005730,GO:0016363,GO:0016607,GO:0042382,GO:0006351,GO:0006355","nucleic acid binding,protein binding,nucleotide binding,RNA binding,nucleoplasm,nucleus,cytoplasm,nucleolus,nuclear matrix,nuclear speck,paraspeckles,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["SFPQ","splicing factor proline/glutamine-rich [Source:HGNC Symbol;Acc:10774]","ENSG00000116560","ENSP00000349748",3,"RRM_1[2],NOPS[1]","family-1078","NONO,PSPC1,SFPQ","NONO","PSPC1[60,54],SFPQ[59,39]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000380","RNA binding,mRNA processing,RNA splicing,alternative mRNA splicing, via spliceosome","GO:0005515,GO:0000166,GO:0003723,GO:0003676,GO:0003677,GO:0042382,GO:0005737,GO:0005654,GO:0016363,GO:0000122,GO:0006351,GO:0006281,GO:0006310,GO:0006397,GO:0008380,GO:0000380","protein binding,nucleotide binding,RNA binding,nucleic acid binding,DNA binding,paraspeckles,cytoplasm,nucleoplasm,nuclear matrix,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,DNA repair,DNA recombination,mRNA processing,RNA splicing,alternative mRNA splicing, via spliceosome","."]
["NUDT21","nudix (nucleoside diphosphate linked moiety X)-type motif 21 [Source:HGNC Symbol;Acc:13870]","ENSG00000167005","ENSP00000300291",1,"NUDIX_2[1]","family-1079","NUDT21",".",".","mRNA","mRNA","The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,1,".","GO:0003729,GO:0005849,GO:0006378,GO:0003723,GO:0017091,GO:0006397,GO:0008380,GO:0000398,GO:0031124","mRNA binding,mRNA cleavage factor complex,mRNA polyadenylation,RNA binding,AU-rich element binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing","GO:0016787,GO:0003729,GO:0005849,GO:0006378,GO:0003723,GO:0005515,GO:0042803,GO:0042826,GO:0017091,GO:0005634,GO:0005654,GO:0005813,GO:0042382,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0051262,GO:0031124,GO:0006369","hydrolase activity,mRNA binding,mRNA cleavage factor complex,mRNA polyadenylation,RNA binding,protein binding,protein homodimerization activity,histone deacetylase binding,AU-rich element binding,nucleus,nucleoplasm,centrosome,paraspeckles,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,protein tetramerization,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["MRPL19","mitochondrial ribosomal protein L19 [Source:HGNC Symbol;Acc:14052]","ENSG00000115364","ENSP00000377486",1,"Ribosomal_L19[1]","family-108","MRPL19",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",1,".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005840,GO:0006412,GO:0005622,GO:0005634,GO:0031965","structural constituent of ribosome,mitochondrion,ribosome,translation,intracellular,nucleus,nuclear membrane","."]
["URM1","ubiquitin related modifier 1 [Source:HGNC Symbol;Acc:28378]","ENSG00000167118","ENSP00000361941",1,"Urm1[1]","family-1080","URM1",".",".","tRNA","putative tRNA",19017811,".",".",".",".",".",".","GO:0002098,GO:0034227","tRNA wobble uridine modification,tRNA thio-modification","GO:0005515,GO:0016783,GO:0005737,GO:0005829,GO:0002098,GO:0034227","protein binding,sulfurtransferase activity,cytoplasm,cytosol,tRNA wobble uridine modification,tRNA thio-modification","."]
["MRPL53","mitochondrial ribosomal protein L53 [Source:HGNC Symbol;Acc:16684]","ENSG00000204822","ENSP00000258105",1,"MRP_L53[1]","family-1081","MRPL53",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["RBM48","RNA binding motif protein 48 [Source:HGNC Symbol;Acc:21785]","ENSG00000127993","ENSP00000419242",1,"RRM_5[1]","family-1082","RBM48",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0000166,GO:0005634,GO:0003723","nucleotide binding,nucleus,RNA binding","."]
["REPIN1","replication initiator 1 [Source:HGNC Symbol;Acc:17922]","ENSG00000214022","ENSP00000417291",10,"zf-C2H2_4[1],zf-Di19[1],zf-H2C2_2[7],zf-C2H2[1]","family-1083","REPIN1",".",".","unknown","unknown","established RBP ",".","novel",".",1,".",".","GO:0022626","cytosolic ribosome","GO:0046872,GO:0003677,GO:0005634,GO:0031965,GO:0005664,GO:0005811,GO:0022626,GO:0006260,GO:2000191,GO:2001273,GO:0003676,GO:0005829","metal ion binding,DNA binding,nucleus,nuclear membrane,nuclear origin of replication recognition complex,lipid particle,cytosolic ribosome,DNA replication,regulation of fatty acid transport,regulation of glucose import in response to insulin stimulus,nucleic acid binding,cytosol","."]
["ZC3H12B","zinc finger CCCH-type containing 12B [Source:HGNC Symbol;Acc:17407]","ENSG00000102053","ENSP00000408077",1,"RNase_Zc3h12a[1]","family-1084","ZC3H12A,ZC3H12B,ZC3H12C,ZC3H12D","ZC3H12A","ZC3H12B[45,32],ZC3H12C[46,31],ZC3H12D[38,43]","unknown","unknown",18178554,".",".",".",".",".",1,".",".","GO:0046872,GO:0004519","metal ion binding,endonuclease activity","."]
["ZC3H12C","zinc finger CCCH-type containing 12C [Source:HGNC Symbol;Acc:29362]","ENSG00000149289","ENSP00000278590",1,"RNase_Zc3h12a[1]","family-1084","ZC3H12A,ZC3H12B,ZC3H12C,ZC3H12D","ZC3H12A","ZC3H12B[45,32],ZC3H12C[46,31],ZC3H12D[38,43]","unknown","unknown",18178554,".",".",".",".",".",1,".",".","GO:0046872,GO:0004519","metal ion binding,endonuclease activity","."]
["ZC3H12D","zinc finger CCCH-type containing 12D [Source:HGNC Symbol;Acc:21175]","ENSG00000178199","ENSP00000374592",1,"RNase_Zc3h12a[1]","family-1084","ZC3H12A,ZC3H12B,ZC3H12C,ZC3H12D","ZC3H12A","ZC3H12B[45,32],ZC3H12C[46,31],ZC3H12D[38,43]","unknown","unknown",18178554,".",".",".",".",".",1,".",".","GO:0046872,GO:0004519,GO:0005634,GO:0005737,GO:0043231,GO:0030308,GO:2000134","metal ion binding,endonuclease activity,nucleus,cytoplasm,intracellular membrane-bounded organelle,negative regulation of cell growth,negative regulation of G1/S transition of mitotic cell cycle","."]
["ZC3H12A","zinc finger CCCH-type containing 12A [Source:HGNC Symbol;Acc:26259]","ENSG00000163874","ENSP00000362179",1,"RNase_Zc3h12a[1]","family-1084","ZC3H12A,ZC3H12B,ZC3H12C,ZC3H12D","ZC3H12A","ZC3H12B[45,32],ZC3H12C[46,31],ZC3H12D[38,43]","ncRNA","viral RNA",23355615,".",".",".",".",".",1,".",".","GO:0005515,GO:0046872,GO:0004519,GO:0005634,GO:0005886,GO:0005737,GO:0010629,GO:0010508,GO:0010884,GO:0006915,GO:0030154,GO:0045600,GO:0001525,GO:0010628,GO:0032088,GO:0071222,GO:2000379,GO:0032720,GO:0045019,GO:0043031,GO:0032715","protein binding,metal ion binding,endonuclease activity,nucleus,plasma membrane,cytoplasm,negative regulation of gene expression,positive regulation of autophagy,positive regulation of lipid storage,apoptotic process,cell differentiation,positive regulation of fat cell differentiation,angiogenesis,positive regulation of gene expression,negative regulation of NF-kappaB transcription factor activity,cellular response to lipopolysaccharide,positive regulation of reactive oxygen species metabolic process,negative regulation of tumor necrosis factor production,negative regulation of nitric oxide biosynthetic process,negative regulation of macrophage activation,negative regulation of interleukin-6 production","."]
["TRMT5","tRNA methyltransferase 5 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:23141]","ENSG00000126814","ENSP00000261249",1,"Met_10[1]","family-1085","TRMT5",".",".","tRNA","tRNA","tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004 [PubMed 15248782]).[supplied by OMIM, Mar 2008]",".",".",".",".",".",".","GO:0052906","tRNA (guanine(37)-N(1))-methyltransferase activity","GO:0016740,GO:0052906,GO:0005634,GO:0005759","transferase activity,tRNA (guanine(37)-N(1))-methyltransferase activity,nucleus,mitochondrial matrix","."]
["TRMT61A","tRNA methyltransferase 61 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:23790]","ENSG00000166166","ENSP00000299202",1,"GCD14[1]","family-1086","TRMT61A",".",".","tRNA","putative tRNA",16043508,".",".",".",".",".",".","GO:0016429,GO:0031515,GO:0030488","tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,tRNA methylation","GO:0016429,GO:0031515,GO:0030488,GO:0005634","tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,tRNA methylation,nucleus","."]
["PABPN1L","poly(A) binding protein, nuclear 1-like (cytoplasmic) [Source:HGNC Symbol;Acc:37237]","ENSG00000205022","ENSP00000408598",1,"RRM_1[1]","family-1087","PABPN1,PABPN1L","PABPN1","PABPN1L[34,38]","mRNA","mRNA",15083517,".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005737","nucleotide binding,RNA binding,nucleic acid binding,cytoplasm","."]
["PABPN1","poly(A) binding protein, nuclear 1 [Source:HGNC Symbol;Acc:8565]","ENSG00000100836","ENSP00000216727",1,"RRM_1[1]","family-1087","PABPN1,PABPN1L","PABPN1","PABPN1L[34,38]","mRNA","mRNA",22502866,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0008380,GO:0000398,GO:0006396,GO:0016973,GO:0031124,GO:0046778","RNA binding,ribonucleoprotein complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing,poly(A)+ mRNA export from nucleus,mRNA 3'-end processing,modification by virus of host mRNA processing","GO:0003676,GO:0000166,GO:0005634,GO:0005737,GO:0003723,GO:0005515,GO:0005654,GO:0030529,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0016973,GO:0006936,GO:0031124,GO:0019048,GO:0019058,GO:0006369,GO:0019054,GO:0046778","nucleic acid binding,nucleotide binding,nucleus,cytoplasm,RNA binding,protein binding,nucleoplasm,ribonucleoprotein complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,poly(A)+ mRNA export from nucleus,muscle contraction,mRNA 3'-end processing,modulation by virus of host morphology or physiology,viral life cycle,termination of RNA polymerase II transcription,modulation by virus of host process,modification by virus of host mRNA processing"," OCULOPHARYNGEAL MUSCULAR DYSTROPHY; OPMD"]
["LSG1","large subunit GTPase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25652]","ENSG00000041802","ENSP00000265245",1,"MMR_HSR1[1]","family-1088","GNL1,LSG1","GNL1","LSG1[24,22]","rRNA","putative rRNA",15660131,".",".",".",".",1,".","GO:0042254","ribosome biogenesis","GO:0005634,GO:0005737,GO:0005525,GO:0003924,GO:0005829,GO:0005783,GO:0015030,GO:0015031,GO:0042254,GO:0006184,GO:0051168","nucleus,cytoplasm,GTP binding,GTPase activity,cytosol,endoplasmic reticulum,Cajal body,protein transport,ribosome biogenesis,GTP catabolic process,nuclear export","."]
["GNL1","guanine nucleotide binding protein-like 1 [Source:HGNC Symbol;Acc:4413]","ENSG00000206412","ENSP00000372942",1,"MMR_HSR1[1]","family-1088","GNL1,LSG1","GNL1","LSG1[24,22]","rRNA","putative rRNA","by homology",".",".",".",".",".",".","GO:0042254","ribosome biogenesis","GO:0005525,GO:0005198,GO:0003924,GO:0005829,GO:0005615,GO:0006974,GO:0042254,GO:0007165,GO:0006184,GO:0002456","GTP binding,structural molecule activity,GTPase activity,cytosol,extracellular space,cellular response to DNA damage stimulus,ribosome biogenesis,signal transduction,GTP catabolic process,T cell mediated immunity","."]
["EEF1G","eukaryotic translation elongation factor 1 gamma [Source:HGNC Symbol;Acc:3213]","ENSG00000254772","ENSP00000331901",3,"EF1G[1],GST_C[1],GST_N[1]","family-1089","EEF1G",".",".","tRNA","tRNA/mRNA","This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit contains an N-terminal glutathione transferase domain, which may be involved in regulating the assembly of multisubunit complexes containing this elongation factor and aminoacyl-tRNA synthetases. [provided by RefSeq, Jul 2008]",".",".",".",".",1,".","GO:0003746,GO:0005853,GO:0006414,GO:0006412","translation elongation factor activity,eukaryotic translation elongation factor 1 complex,translational elongation,translation","GO:0005515,GO:0003746,GO:0005853,GO:0006414,GO:0005829,GO:0005622,GO:0009615,GO:0006412,GO:0010467,GO:0044267","protein binding,translation elongation factor activity,eukaryotic translation elongation factor 1 complex,translational elongation,cytosol,intracellular,response to virus,translation,gene expression,cellular protein metabolic process","."]
["RBM33","RNA binding motif protein 33 [Source:HGNC Symbol;Acc:27223]","ENSG00000184863","ENSP00000376510",1,"RRM_6[1]","family-109","RBM33",".",".","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0003676,GO:0000166,GO:0003723","nucleic acid binding,nucleotide binding,RNA binding","."]
["RPP25","ribonuclease P/MRP 25kDa subunit [Source:HGNC Symbol;Acc:30361]","ENSG00000178718","ENSP00000317691",1,"Alba[1]","family-1090","RPP25,RPP25L","RPP25","RPP25L[36,44]","ncRNA","P/MRP RNA",12003489,".","RNAbinding",".",1,".",".","GO:0003723,GO:0004526,GO:0008033","RNA binding,ribonuclease P activity,tRNA processing","GO:0003723,GO:0005515,GO:0003676,GO:0004526,GO:0005634,GO:0005739,GO:0005813,GO:0008033","RNA binding,protein binding,nucleic acid binding,ribonuclease P activity,nucleus,mitochondrion,centrosome,tRNA processing","."]
["RPP25L","ribonuclease P/MRP 25kDa subunit-like [Source:HGNC Symbol;Acc:19909]","ENSG00000164967","ENSP00000297613",1,"Alba[1]","family-1090","RPP25,RPP25L","RPP25","RPP25L[36,44]","ncRNA","P/MRP RNA","by homology","RNAbinding",".",".",1,".",".",".",".","GO:0003676,GO:0005634","nucleic acid binding,nucleus","."]
["RPP38","ribonuclease P/MRP 38kDa subunit [Source:HGNC Symbol;Acc:30329]","ENSG00000152464","ENSP00000367443",1,"Ribosomal_L7Ae[1]","family-1091","RPP38",".",".","ncRNA","P/MRP RNA",11455963,".",".",".",".",".",".","GO:0004526,GO:0005655,GO:0008033","ribonuclease P activity,nucleolar ribonuclease P complex,tRNA processing","GO:0005515,GO:0004526,GO:0005634,GO:0005655,GO:0008033","protein binding,ribonuclease P activity,nucleus,nucleolar ribonuclease P complex,tRNA processing","."]
["GARS","glycyl-tRNA synthetase [Source:HGNC Symbol;Acc:4162]","ENSG00000106105","ENSP00000373918",3,"tRNA-synt_2b[1],HGTP_anticodon[1],WHEP-TRS[1]","family-1092","GARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004820,GO:0006418,GO:0006426","aminoacyl-tRNA ligase activity,glycine-tRNA ligase activity,tRNA aminoacylation for protein translation,glycyl-tRNA aminoacylation","GO:0005515,GO:0000166,GO:0005524,GO:0046983,GO:0004812,GO:0004820,GO:0005739,GO:0005737,GO:0005829,GO:0005759,GO:0030141,GO:0010467,GO:0006418,GO:0008219,GO:0015966,GO:0006426","protein binding,nucleotide binding,ATP binding,protein dimerization activity,aminoacyl-tRNA ligase activity,glycine-tRNA ligase activity,mitochondrion,cytoplasm,cytosol,mitochondrial matrix,secretory granule,gene expression,tRNA aminoacylation for protein translation,cell death,diadenosine tetraphosphate biosynthetic process,glycyl-tRNA aminoacylation"," NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE VA; HMN5A"]
["DRG2","developmentally regulated GTP binding protein 2 [Source:HGNC Symbol;Acc:3030]","ENSG00000108591","ENSP00000225729",2,"MMR_HSR1[1],TGS[1]","family-1093","DRG2",".",".","mRNA","putative mRNA","RBG1 yeast homolog",".",".",".",".",".",".",".",".","GO:0005525,GO:0015093,GO:0016021,GO:0015684,GO:0005737,GO:0005739,GO:0007165","GTP binding,ferrous iron transmembrane transporter activity,integral to membrane,ferrous iron transport,cytoplasm,mitochondrion,signal transduction","."]
["TRMU","tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase [Source:HGNC Symbol;Acc:25481]","ENSG00000100416","ENSP00000370407",1,"tRNA_Me_trans[1]","family-1094","TRMU",".",".","tRNA","tRNA","This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]",".",".",".",".",".",".","GO:0008033,GO:0000049,GO:0004808,GO:0006399","tRNA processing,tRNA binding,tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity,tRNA metabolic process","GO:0016740,GO:0008168,GO:0005737,GO:0008033,GO:0005524,GO:0000049,GO:0004066,GO:0004808,GO:0016783,GO:0005739,GO:0006529,GO:0006399","transferase activity,methyltransferase activity,cytoplasm,tRNA processing,ATP binding,tRNA binding,asparagine synthase (glutamine-hydrolyzing) activity,tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity,sulfurtransferase activity,mitochondrion,asparagine biosynthetic process,tRNA metabolic process"," DEAFNESS, AMINOGLYCOSIDE-INDUCED"]
["GNL2","guanine nucleotide binding protein-like 2 (nucleolar) [Source:HGNC Symbol;Acc:29925]","ENSG00000134697","ENSP00000362153",2,"MMR_HSR1[1],NGP1NT[1]","family-1095","GNL2",".",".","rRNA","putative rRNA","NOG2 yeast homolog","candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005525,GO:0015093,GO:0016021,GO:0015684,GO:0003924,GO:0005634,GO:0005730,GO:0042254,GO:0006184","GTP binding,ferrous iron transmembrane transporter activity,integral to membrane,ferrous iron transport,GTPase activity,nucleus,nucleolus,ribosome biogenesis,GTP catabolic process","."]
["CPSF2","cleavage and polyadenylation specific factor 2, 100kDa [Source:HGNC Symbol;Acc:2325]","ENSG00000165934","ENSP00000298875",4,"RMMBL[1],Beta-Casp[1],Lactamase_B[1],CPSF100_C[1]","family-1096","CPSF2",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0005847,GO:0006379,GO:0006378,GO:0003723,GO:0008380,GO:0000398,GO:0006406,GO:0006398,GO:0031124","mRNA cleavage and polyadenylation specificity factor complex,mRNA cleavage,mRNA polyadenylation,RNA binding,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,histone mRNA 3'-end processing,mRNA 3'-end processing","GO:0016787,GO:0005847,GO:0006379,GO:0006378,GO:0003723,GO:0005515,GO:0005654,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006406,GO:0006398,GO:0031124,GO:0006369","hydrolase activity,mRNA cleavage and polyadenylation specificity factor complex,mRNA cleavage,mRNA polyadenylation,RNA binding,protein binding,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,histone mRNA 3'-end processing,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["CD3EAP","CD3e molecule, epsilon associated protein [Source:HGNC Symbol;Acc:24219]","ENSG00000117877","ENSP00000310966",1,"RNA_polI_A34[1]","family-1097","CD3EAP",".",".","rRNA","putative rRNA",16809778,".","RNArelated",".",1,".",".","GO:0009303","rRNA transcription","GO:0003899,GO:0005634,GO:0005737,GO:0005739,GO:0005694,GO:0005730,GO:0000120,GO:0005736,GO:0007169,GO:0009303,GO:0005515","DNA-directed RNA polymerase activity,nucleus,cytoplasm,mitochondrion,chromosome,nucleolus,RNA polymerase I transcription factor complex,DNA-directed RNA polymerase I complex,transmembrane receptor protein tyrosine kinase signaling pathway,rRNA transcription,protein binding","."]
["HDLBP","high density lipoprotein binding protein [Source:HGNC Symbol;Acc:4857]","ENSG00000115677","ENSP00000312042",14,"KH_1[14]","family-1098","HDLBP",".",".","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0008289,GO:0005634,GO:0005886,GO:0005737,GO:0034364,GO:0008203,GO:0006869","RNA binding,lipid binding,nucleus,plasma membrane,cytoplasm,high-density lipoprotein particle,cholesterol metabolic process,lipid transport","."]
["RDM1","RAD52 motif 1 [Source:HGNC Symbol;Acc:19950]","ENSG00000187456","ENSP00000378035",1,"RRM_1[1]","family-1099","RDM1",".",".","unknown","unknown",15611051,".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0003677,GO:0005737,GO:0005730,GO:0016605,GO:0015030,GO:0006281,GO:0006310","nucleotide binding,RNA binding,nucleic acid binding,DNA binding,cytoplasm,nucleolus,PML body,Cajal body,DNA repair,DNA recombination","."]
["BYSL","bystin-like [Source:HGNC Symbol;Acc:1157]","ENSG00000112578","ENSP00000230340",1,"Bystin[1]","family-11","BYSL",".",".","rRNA","rRNA",20805244,".","novel",".",1,1,".","GO:0000462","maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0005634,GO:0043231,GO:0005730,GO:0005515,GO:0005737,GO:0045177,GO:0001701,GO:0001825,GO:0008283,GO:0007155,GO:0007565,GO:0001829,GO:0000462","nucleus,intracellular membrane-bounded organelle,nucleolus,protein binding,cytoplasm,apical part of cell,in utero embryonic development,blastocyst formation,cell proliferation,cell adhesion,female pregnancy,trophectodermal cell differentiation,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["GEMIN8","gem (nuclear organelle) associated protein 8 [Source:HGNC Symbol;Acc:26044]","ENSG00000046647","ENSP00000369895",1,"GEMIN8[1]","family-110","GEMIN8",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005681,GO:0032797,GO:0000387","spliceosomal complex,SMN complex,spliceosomal snRNP assembly","GO:0005515,GO:0005634,GO:0005737,GO:0005681,GO:0097504,GO:0032797,GO:0000387","protein binding,nucleus,cytoplasm,spliceosomal complex,Gemini of coiled bodies,SMN complex,spliceosomal snRNP assembly","."]
["XPO5","exportin 5 [Source:HGNC Symbol;Acc:17675]","ENSG00000124571","ENSP00000265351",1,"Xpo1[1]","family-1100","XPO5",".",".","ncRNA","miRNA/tRNA/mRNA/viral RNA",21297638,"RNAbinding","experimentally validated",1,1,1,".","GO:0000049,GO:0003723,GO:0031047","tRNA binding,RNA binding,gene silencing by RNA","GO:0000049,GO:0008565,GO:0005488,GO:0006611,GO:0003723,GO:0005515,GO:0008536,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0010467,GO:0031047,GO:0006886","tRNA binding,protein transporter activity,binding,protein export from nucleus,RNA binding,protein binding,Ran GTPase binding,nucleus,cytoplasm,cytosol,nucleoplasm,gene expression,gene silencing by RNA,intracellular protein transport","."]
["ZNF622","zinc finger protein 622 [Source:HGNC Symbol;Acc:30958]","ENSG00000173545","ENSP00000310042",2,"zf-C2H2_jaz[1],zf-C2H2_2[1]","family-1101","ZNF622",".",".","unknown","RNA related","established RBP ",".","novel",".",1,".",".",".",".","GO:0005515,GO:0008270,GO:0003676,GO:0005737,GO:0005730,GO:0005794,GO:0043065,GO:0046330,GO:0043410,GO:0008631,GO:0033674","protein binding,zinc ion binding,nucleic acid binding,cytoplasm,nucleolus,Golgi apparatus,positive regulation of apoptotic process,positive regulation of JNK cascade,positive regulation of MAPK cascade,intrinsic apoptotic signaling pathway in response to oxidative stress,positive regulation of kinase activity","."]
["DZIP1","DAZ interacting protein 1 [Source:HGNC Symbol;Acc:20908]","ENSG00000134874","ENSP00000257312",2,"Dzip-like_N[1],zf-C2H2[1]","family-1102","DZIP1,DZIP1L","DZIP1","DZIP1L[26,30]","mRNA","mRNA",12511597,".",".",".",".",".",".",".",".","GO:0005515,GO:0046872,GO:0005634,GO:0036064,GO:0005737,GO:0005814,GO:0043234,GO:0042384,GO:0007275,GO:0007283,GO:0007281","protein binding,metal ion binding,nucleus,ciliary basal body,cytoplasm,centriole,protein complex,cilium assembly,multicellular organismal development,spermatogenesis,germ cell development","."]
["DZIP1L","DAZ interacting zinc finger protein 1-like [Source:HGNC Symbol;Acc:26551]","ENSG00000158163","ENSP00000332148",1,"Dzip-like_N[1]","family-1102","DZIP1,DZIP1L","DZIP1","DZIP1L[26,30]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".","GO:0046872,GO:0036064,GO:0005814,GO:0042384","metal ion binding,ciliary basal body,centriole,cilium assembly","."]
["GSPT1","G1 to S phase transition 1 [Source:HGNC Symbol;Acc:4621]","ENSG00000103342","ENSP00000408399",3,"PAM2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-1103","GSPT1,GSPT2,HBS1L","GSPT1","GSPT2[86,87],HBS1L[33,31]","mRNA","mRNA","23019593, 15326224 ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0003747,GO:0000184","translation release factor activity,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005525,GO:0003924,GO:0005515,GO:0003747,GO:0005622,GO:0006479,GO:0000082,GO:0006184,GO:0000184","GTP binding,GTPase activity,protein binding,translation release factor activity,intracellular,protein methylation,G1/S transition of mitotic cell cycle,GTP catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["HBS1L","HBS1-like (S. cerevisiae) [Source:HGNC Symbol;Acc:4834]","ENSG00000112339","ENSP00000389826",4,"HBS1_N[1],GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-1103","GSPT1,GSPT2,HBS1L","GSPT1","GSPT2[86,87],HBS1L[33,31]","mRNA","putative mRNA","HBS1 yeast homolog: GTPase with similarity to translation release factors; together with binding partner Dom34p, facilitates ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled; genetically implicated in mRNA no-go decay; HBS1 has a paralog, SKI7, that arose from the whole genome duplication",".",".",".",".",".",".","GO:0003746,GO:0006412","translation elongation factor activity,translation","GO:0005525,GO:0003924,GO:0003746,GO:0006412,GO:0007165","GTP binding,GTPase activity,translation elongation factor activity,translation,signal transduction","."]
["GSPT2","G1 to S phase transition 2 [Source:HGNC Symbol;Acc:4622]","ENSG00000268273","ENSP00000470900",3,"PAM2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-1103","GSPT1,GSPT2,HBS1L","GSPT1","GSPT2[86,87],HBS1L[33,31]","mRNA","mRNA","This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010]","candidate mRNA binder","novel",1,1,".",".","GO:0006412,GO:0016070,GO:0016071,GO:0000184,GO:0006415","translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0005525,GO:0003924,GO:0005829,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0007049,GO:0044267,GO:0000184,GO:0006415","protein binding,GTP binding,GTPase activity,cytosol,translation,gene expression,RNA metabolic process,mRNA metabolic process,cell cycle,cellular protein metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","."]
["EIF2D","eukaryotic translation initiation factor 2D [Source:HGNC Symbol;Acc:6583]","ENSG00000143486","ENSP00000271764",2,"PUA[1],SUI1[1]","family-1104","EIF2D",".",".","tRNA","tRNA","EIF2D This gene encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. This gene was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]",".",".",".",".",1,1,"GO:0003723,GO:0003743,GO:0006413","RNA binding,translation initiation factor activity,translational initiation","GO:0003723,GO:0005515,GO:0004872,GO:0003743,GO:0005737,GO:0006886,GO:0006413","RNA binding,protein binding,receptor activity,translation initiation factor activity,cytoplasm,intracellular protein transport,translational initiation","."]
["METTL1","methyltransferase like 1 [Source:HGNC Symbol;Acc:7030]","ENSG00000037897","ENSP00000314441",1,"Methyltransf_4[1]","family-1105","METTL1",".",".","tRNA","tRNA",12403464,".",".",".",".",".",".","GO:0008176,GO:0006400,GO:0000049,GO:0036265","tRNA (guanine-N7-)-methyltransferase activity,tRNA modification,tRNA binding,RNA (guanine-N7)-methylation","GO:0008176,GO:0006400,GO:0005515,GO:0000049,GO:0005634,GO:0005737,GO:0043231,GO:0036265","tRNA (guanine-N7-)-methyltransferase activity,tRNA modification,protein binding,tRNA binding,nucleus,cytoplasm,intracellular membrane-bounded organelle,RNA (guanine-N7)-methylation","."]
["RNASEH1","ribonuclease H1 [Source:HGNC Symbol;Acc:18466]","ENSG00000171865","ENSP00000313350",2,"RNase_H[1],Cauli_VI[1]","family-1106","RNASEH1",".",".","diverse","RNA/DNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004540,GO:0004523,GO:0006401","RNA binding,ribonuclease activity,ribonuclease H activity,RNA catabolic process","GO:0003723,GO:0042803,GO:0003676,GO:0000287,GO:0004540,GO:0004523,GO:0005634,GO:0005739,GO:0006264,GO:0006401","RNA binding,protein homodimerization activity,nucleic acid binding,magnesium ion binding,ribonuclease activity,ribonuclease H activity,nucleus,mitochondrion,mitochondrial DNA replication,RNA catabolic process","."]
["ZNHIT6","zinc finger, HIT-type containing 6 [Source:HGNC Symbol;Acc:26089]","ENSG00000117174","ENSP00000414344",1,"zf-HIT[1]","family-1107","ZNHIT6",".",".","snoRNA","snoRNA",17636026,".",".",".",".",1,".","GO:0070761,GO:0042254,GO:0000492","pre-snoRNP complex,ribosome biogenesis,box C/D snoRNP assembly","GO:0005515,GO:0046872,GO:0042802,GO:0070761,GO:0042254,GO:0000492","protein binding,metal ion binding,identical protein binding,pre-snoRNP complex,ribosome biogenesis,box C/D snoRNP assembly","."]
["DARS2","aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:25538]","ENSG00000117593","ENSP00000355086",2,"tRNA-synt_2[1],tRNA_anti-codon[1]","family-1108","DARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0006418,GO:0000049,GO:0004815,GO:0043039,GO:0070145","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,tRNA binding,aspartate-tRNA ligase activity,tRNA aminoacylation,mitochondrial asparaginyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0005737,GO:0006418,GO:0005515,GO:0042803,GO:0016874,GO:0003676,GO:0000049,GO:0004815,GO:0050560,GO:0005739,GO:0005634,GO:0005759,GO:0010467,GO:0043039,GO:0070145","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,protein binding,protein homodimerization activity,ligase activity,nucleic acid binding,tRNA binding,aspartate-tRNA ligase activity,aspartate-tRNA(Asn) ligase activity,mitochondrion,nucleus,mitochondrial matrix,gene expression,tRNA aminoacylation,mitochondrial asparaginyl-tRNA aminoacylation"," LEUKOENCEPHALOPATHY WITH BRAINSTEM AND SPINAL CORD INVOLVEMENT AND"]
["SNRPD2","small nuclear ribonucleoprotein D2 polypeptide 16.5kDa [Source:HGNC Symbol;Acc:11159]","ENSG00000125743","ENSP00000468247",1,"LSM[1]","family-1109","SNRPD2",".",".","snRNA","snRNA","established RBP ",".","RNArelated",".",1,".",1,"GO:0030532,GO:0008380,GO:0005681,GO:0005689,GO:0071013,GO:0016070,GO:0000398,GO:0000245,GO:0000387,GO:0034660","small nuclear ribonucleoprotein complex,RNA splicing,spliceosomal complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0030532,GO:0008380,GO:0005515,GO:0005829,GO:0005654,GO:0005681,GO:0005689,GO:0071013,GO:0010467,GO:0016070,GO:0000398,GO:0000245,GO:0000387,GO:0034660","small nuclear ribonucleoprotein complex,RNA splicing,protein binding,cytosol,nucleoplasm,spliceosomal complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,gene expression,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["DICER1","dicer 1, ribonuclease type III [Source:HGNC Symbol;Acc:17098]","ENSG00000100697","ENSP00000437256",7,"Helicase_C[1],Dicer_dimer[1],dsrm[1],PAZ[1],DEAD[1],Ribonuclease_3[2]","family-111","DICER1",".",".","ncRNA","miRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003725,GO:0004525,GO:0035198,GO:0016891,GO:0006396,GO:0031054,GO:0030422,GO:2000630,GO:0035196,GO:0030423","RNA binding,double-stranded RNA binding,ribonuclease III activity,miRNA binding,endoribonuclease activity, producing 5'-phosphomonoesters,RNA processing,pre-miRNA processing,production of siRNA involved in RNA interference,positive regulation of miRNA metabolic process,production of miRNAs involved in gene silencing by miRNA,targeting of mRNA for destruction involved in RNA interference","GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0046872,GO:0003677,GO:0003725,GO:0008026,GO:0016787,GO:0004386,GO:0004525,GO:0035198,GO:0016891,GO:0005829,GO:0016442,GO:0000122,GO:0045944,GO:0006915,GO:0043066,GO:0035264,GO:0001525,GO:0051225,GO:0010467,GO:0009791,GO:0006396,GO:0021889,GO:0021987,GO:0051726,GO:0060119,GO:0019827,GO:0055013,GO:0031069,GO:0035116,GO:0048754,GO:0051607,GO:0021675,GO:0030324,GO:0048812,GO:0021522,GO:0048536,GO:0031054,GO:0014040,GO:0010626,GO:0031643,GO:0030422,GO:0045069,GO:0010070,GO:0070173,GO:0060576,GO:0045664,GO:2000630,GO:0035196,GO:0030423,GO:0048713,GO:0071335,GO:0032290,GO:0030425,GO:0030424,GO:0030426,GO:0005793,GO:0010468,GO:0050767,GO:0008283,GO:0048565,GO:0030326,GO:0001942,GO:0010628,GO:0045595,GO:0048730,GO:0031641,GO:0042487","RNA binding,protein binding,ATP binding,nucleic acid binding,metal ion binding,DNA binding,double-stranded RNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,ribonuclease III activity,miRNA binding,endoribonuclease activity, producing 5'-phosphomonoesters,cytosol,RISC complex,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,apoptotic process,negative regulation of apoptotic process,multicellular organism growth,angiogenesis,spindle assembly,gene expression,post-embryonic development,RNA processing,olfactory bulb interneuron differentiation,cerebral cortex development,regulation of cell cycle,inner ear receptor cell development,stem cell maintenance,cardiac muscle cell development,hair follicle morphogenesis,embryonic hindlimb morphogenesis,branching morphogenesis of an epithelial tube,defense response to virus,nerve development,lung development,neuron projection morphogenesis,spinal cord motor neuron differentiation,spleen development,pre-miRNA processing,positive regulation of Schwann cell differentiation,negative regulation of Schwann cell proliferation,positive regulation of myelination,production of siRNA involved in RNA interference,regulation of viral genome replication,zygote asymmetric cell division,regulation of enamel mineralization,intestinal epithelial cell development,regulation of neuron differentiation,positive regulation of miRNA metabolic process,production of miRNAs involved in gene silencing by miRNA,targeting of mRNA for destruction involved in RNA interference,regulation of oligodendrocyte differentiation,hair follicle cell proliferation,peripheral nervous system myelin formation,dendrite,axon,growth cone,endoplasmic reticulum-Golgi intermediate compartment,regulation of gene expression,regulation of neurogenesis,cell proliferation,digestive tract development,embryonic limb morphogenesis,hair follicle development,positive regulation of gene expression,regulation of cell differentiation,epidermis morphogenesis,regulation of myelination,regulation of odontogenesis of dentin-containing tooth"," GOITER, MULTINODULAR 1, WITH OR WITHOUT SERTOLI-LEYDIG CELL TUMORS;"]
["DYNLL1","dynein, light chain, LC8-type 1 [Source:HGNC Symbol;Acc:15476]","ENSG00000088986","ENSP00000376297",1,"Dynein_light[1]","family-1110","DNAL4,DYNLL2,DYNLL1","DNAL4","DYNLL2[27,31],DYNLL1[29,34]","mRNA","mRNA",10683380,".",".",".",".",".",".",".",".","GO:0042803,GO:0019904,GO:0019899,GO:0008022,GO:0030235,GO:0016020,GO:0005829,GO:0005875,GO:0007017,GO:0005515,GO:0003774,GO:0005634,GO:0005886,GO:0005737,GO:0005739,GO:0005874,GO:0008180,GO:0005813,GO:0000776,GO:0072686,GO:0005868,GO:0006351,GO:0006915,GO:0006355,GO:0000278,GO:0006810,GO:0030036,GO:0000086,GO:0097193,GO:0007292,GO:0042326,GO:0019886,GO:0019048,GO:0009653,GO:1900740,GO:0005856","protein homodimerization activity,protein domain specific binding,enzyme binding,protein C-terminus binding,nitric-oxide synthase regulator activity,membrane,cytosol,microtubule associated complex,microtubule-based process,protein binding,motor activity,nucleus,plasma membrane,cytoplasm,mitochondrion,microtubule,COP9 signalosome,centrosome,kinetochore,mitotic spindle,cytoplasmic dynein complex,transcription, DNA-templated,apoptotic process,regulation of transcription, DNA-dependent,mitotic cell cycle,transport,actin cytoskeleton organization,G2/M transition of mitotic cell cycle,intrinsic apoptotic signaling pathway,female gamete generation,negative regulation of phosphorylation,antigen processing and presentation of exogenous peptide antigen via MHC class II,modulation by virus of host morphology or physiology,anatomical structure morphogenesis,positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway,cytoskeleton","."]
["ZNF638","zinc finger protein 638 [Source:HGNC Symbol;Acc:17894]","ENSG00000075292","ENSP00000386433",4,"RRM_5[2],zf-C2H2_jaz[1],RRM_6[1]","family-1111","ZNF638",".",".","mRNA","putative mRNA",8647861,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0008380","RNA binding,RNA splicing","GO:0000166,GO:0003723,GO:0008270,GO:0003676,GO:0003690,GO:0005634,GO:0005737,GO:0043231,GO:0005654,GO:0016607,GO:0006351,GO:0006355,GO:0008380","nucleotide binding,RNA binding,zinc ion binding,nucleic acid binding,double-stranded DNA binding,nucleus,cytoplasm,intracellular membrane-bounded organelle,nucleoplasm,nuclear speck,transcription, DNA-templated,regulation of transcription, DNA-dependent,RNA splicing","."]
["SAMD4B","sterile alpha motif domain containing 4B [Source:HGNC Symbol;Acc:25492]","ENSG00000179134","ENSP00000317224",2,"PHAT[1],SAM_1[1]","family-112","SAMD4A,SAMD4B","SAMD4A","SAMD4B[62,64]","mRNA","mRNA",16221671,"candidate mRNA binder",".",".",1,".",1,".",".","GO:0005515,GO:0005634,GO:0005737,GO:0006351,GO:0006355","protein binding,nucleus,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["SAMD4A","sterile alpha motif domain containing 4A [Source:HGNC Symbol;Acc:23023] [Type: protein coding Ensembl/Havana merge]","ENSG00000020577","ENSP00000375919",1,"SAM_1[1]","family-112","SAMD4A,SAMD4B","SAMD4A","SAMD4B[62,64]","mRNA","mRNA","Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008]",".","novel",".",1,".",1,"GO:0030371,GO:0045727","translation repressor activity,positive regulation of translation","GO:0005515,GO:0045202,GO:0030371,GO:0005737,GO:0030054,GO:0030425,GO:0045727,GO:0017148","protein binding,synapse,translation repressor activity,cytoplasm,cell junction,dendrite,positive regulation of translation,negative regulation of translation","."]
["RTF1","Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28996]","ENSG00000137815","ENSP00000452973",2,"Plus-3[1],SYF2[1]","family-113","RTF1",".",".","mRNA","putative mRNA","RNA pol II complex",".","RNArelated",".",1,".",".",".",".","GO:0003677,GO:0005634,GO:0006352,GO:0016570,GO:0005515,GO:0003697,GO:0005730,GO:0016593,GO:0000122,GO:0019827,GO:0001711,GO:0045944,GO:0016055,GO:0051571,GO:0080182,GO:0032968","DNA binding,nucleus,DNA-dependent transcription, initiation,histone modification,protein binding,single-stranded DNA binding,nucleolus,Cdc73/Paf1 complex,negative regulation of transcription from RNA polymerase II promoter,stem cell maintenance,endodermal cell fate commitment,positive regulation of transcription from RNA polymerase II promoter,Wnt signaling pathway,positive regulation of histone H3-K4 methylation,histone H3-K4 trimethylation,positive regulation of transcription elongation from RNA polymerase II promoter","."]
["CNOT4","CCR4-NOT transcription complex, subunit 4 [Source:HGNC Symbol;Acc:7880]","ENSG00000080802","ENSP00000388491",2,"RRM_5[1],zf-RING_4[1]","family-114","CNOT4",".",".","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0016070,GO:0016071,GO:0000288,GO:0000289","RNA binding,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening","GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0004842,GO:0005634,GO:0005829,GO:0030014,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0051865","nucleotide binding,RNA binding,protein binding,zinc ion binding,nucleic acid binding,ubiquitin-protein ligase activity,nucleus,cytosol,CCR4-NOT complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,protein autoubiquitination","."]
["TARBP2","TAR (HIV-1) RNA binding protein 2 [Source:HGNC Symbol;Acc:11569]","ENSG00000139546","ENSP00000266987",2,"dsrm[2]","family-115","PRKRA,TARBP2","PRKRA","TARBP2[48,41]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003725,GO:0035197,GO:0035198,GO:0006417,GO:0031054,GO:0030422,GO:0035280,GO:0030423","double-stranded RNA binding,siRNA binding,miRNA binding,regulation of translation,pre-miRNA processing,production of siRNA involved in RNA interference,miRNA loading onto RISC involved in gene silencing by miRNA,targeting of mRNA for destruction involved in RNA interference","GO:0005515,GO:0042803,GO:0003725,GO:0035197,GO:0035198,GO:0005634,GO:0005737,GO:0005829,GO:0048471,GO:0016442,GO:0006355,GO:0010467,GO:0006417,GO:0006357,GO:0006469,GO:0031054,GO:0030422,GO:0035280,GO:0046782,GO:0050689,GO:0045070,GO:0030423","protein binding,protein homodimerization activity,double-stranded RNA binding,siRNA binding,miRNA binding,nucleus,cytoplasm,cytosol,perinuclear region of cytoplasm,RISC complex,regulation of transcription, DNA-dependent,gene expression,regulation of translation,regulation of transcription from RNA polymerase II promoter,negative regulation of protein kinase activity,pre-miRNA processing,production of siRNA involved in RNA interference,miRNA loading onto RISC involved in gene silencing by miRNA,regulation of viral transcription,negative regulation of defense response to virus by host,positive regulation of viral genome replication,targeting of mRNA for destruction involved in RNA interference","."]
["PRKRA","protein kinase, interferon-inducible double stranded RNA dependent activator [Source:HGNC Symbol;Acc:9438]","ENSG00000180228","ENSP00000430604",2,"dsrm[2]","family-115","PRKRA,TARBP2","PRKRA","TARBP2[48,41]","ncRNA","viral RNA/ miRNA, siRNA","This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]","RNAbinding",".",".",1,".",".","GO:0003723,GO:0030422","RNA binding,production of siRNA involved in RNA interference","GO:0016301,GO:0005622,GO:0006950,GO:0006468,GO:0042473,GO:0042474,GO:0048705,GO:0003723,GO:0005515,GO:0042803,GO:0008047,GO:0005737,GO:0005829,GO:0048471,GO:0008285,GO:0009615,GO:0006955,GO:0010467,GO:0043085,GO:0030422,GO:0034599,GO:2001244","kinase activity,intracellular,response to stress,protein phosphorylation,outer ear morphogenesis,middle ear morphogenesis,skeletal system morphogenesis,RNA binding,protein binding,protein homodimerization activity,enzyme activator activity,cytoplasm,cytosol,perinuclear region of cytoplasm,negative regulation of cell proliferation,response to virus,immune response,gene expression,positive regulation of catalytic activity,production of siRNA involved in RNA interference,cellular response to oxidative stress,positive regulation of intrinsic apoptotic signaling pathway"," DYSTONIA 16; DYT16"]
["GLE1","GLE1 RNA export mediator homolog (yeast) [Source:HGNC Symbol;Acc:4315]","ENSG00000119392","ENSP00000438670",1,"GLE1[1]","family-116","GLE1",".",".","mRNA","mRNA","This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0016973,GO:0006406","poly(A)+ mRNA export from nucleus,mRNA export from nucleus","GO:0005643,GO:0016973,GO:0005737,GO:0015031,GO:0006406","nuclear pore,poly(A)+ mRNA export from nucleus,cytoplasm,protein transport,mRNA export from nucleus"," LETHAL CONGENITAL CONTRACTURE SYNDROME 1; LCCS1"]
["EXOSC2","exosome component 2 [Source:HGNC Symbol;Acc:17097]","ENSG00000130713","ENSP00000361427",1,"ECR1_N[1]","family-117","EXOSC2",".",".","diverse","diverse","established RBP ",".",".",".",".",1,".","GO:0003723,GO:0004527,GO:0000178,GO:0008312,GO:0000175,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","RNA binding,exonuclease activity,exosome (RNase complex),7S RNA binding,3'-5'-exoribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0004527,GO:0000178,GO:0005515,GO:0008312,GO:0000175,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0030307,GO:0043928","RNA binding,exonuclease activity,exosome (RNase complex),protein binding,7S RNA binding,3'-5'-exoribonuclease activity,nucleus,cytoplasm,cytosol,nucleolus,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,positive regulation of cell growth,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["SSU72","SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25016]","ENSG00000160075","ENSP00000291386",1,"Ssu72[1]","family-118","SSU72",".",".","mRNA","putative mRNA",12944462,".",".",".",".",".",".","GO:0006397,GO:0006378","mRNA processing,mRNA polyadenylation","GO:0005515,GO:0004721,GO:0008420,GO:0005634,GO:0005737,GO:0006397,GO:0006378,GO:0070940","protein binding,phosphoprotein phosphatase activity,CTD phosphatase activity,nucleus,cytoplasm,mRNA processing,mRNA polyadenylation,dephosphorylation of RNA polymerase II C-terminal domain","."]
["GTPBP10","GTP-binding protein 10 (putative) [Source:HGNC Symbol;Acc:25106]","ENSG00000105793","ENSP00000222511",2,"MMR_HSR1[1],GTP1_OBG[1]","family-119","GTPBP10,MTG2","GTPBP10","MTG2[34,33]","unknown","RNA related","established RBP ",".","novel",".",1,".",".","GO:0042254","ribosome biogenesis","GO:0005525,GO:0000287,GO:0003924,GO:0005739,GO:0005694,GO:0005730,GO:0042254,GO:0015093,GO:0016021,GO:0015684","GTP binding,magnesium ion binding,GTPase activity,mitochondrion,chromosome,nucleolus,ribosome biogenesis,ferrous iron transmembrane transporter activity,integral to membrane,ferrous iron transport","."]
["RPL10A","ribosomal protein L10a [Source:HGNC Symbol;Acc:10299]","ENSG00000198755","ENSP00000363018",1,"Ribosomal_L1[1]","family-12","RPL10A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0022625,GO:0015934,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,cytosolic large ribosomal subunit,large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005829,GO:0022625,GO:0015934,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0009653,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytosol,cytosolic large ribosomal subunit,large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,anatomical structure morphogenesis,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["HENMT1","HEN1 methyltransferase homolog 1 (Arabidopsis) [Source:HGNC Symbol;Acc:26400] [Type: protein coding Ensembl/Havana merge]","ENSG00000162639","ENSP00000359049",1,"Methyltransf_23[1]","family-120","HENMT1",".",".","ncRNA","piRNA/miRNA",17604629,".",".",".",".",".",".","GO:0003723,GO:0008173,GO:0043186,GO:0031047,GO:0001510,GO:0034587","RNA binding,RNA methyltransferase activity,P granule,gene silencing by RNA,RNA methylation,piRNA metabolic process","GO:0003723,GO:0046872,GO:0008171,GO:0008173,GO:0043186,GO:0031047,GO:0001510,GO:0034587","RNA binding,metal ion binding,O-methyltransferase activity,RNA methyltransferase activity,P granule,gene silencing by RNA,RNA methylation,piRNA metabolic process","."]
["THOC2","THO complex 2 [Source:HGNC Symbol;Acc:19073]","ENSG00000125676","ENSP00000347959",2,"Tho2[1],Thoc2[1]","family-121","THOC2",".",".","mRNA","mRNA","The TREX multiprotein complex binds specifically to spliced mRNAs to facilitate mRNA export. The protein encoded by this gene is a member of the THO complex, a subset of the TREX complex. The encoded protein interacts with the THOC1 protein.[provided by RefSeq, Jun 2010]",".",".",".",".",".",".","GO:0003723,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0016973,GO:0006406","RNA binding,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,poly(A)+ mRNA export from nucleus,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0016607,GO:0000346,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0016973,GO:0006406,GO:0046784","RNA binding,protein binding,nuclear speck,transcription export complex,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,poly(A)+ mRNA export from nucleus,mRNA export from nucleus,viral mRNA export from host cell nucleus","."]
["ENDOG","endonuclease G [Source:HGNC Symbol;Acc:3346]","ENSG00000167136","ENSP00000361725",1,"Endonuclease_NS[1]","family-122","ENDOG,EXOG","ENDOG","EXOG[33,27]","diverse","diverse","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0046872,GO:0004519,GO:0016787,GO:0005739,GO:0046677,GO:0006310,GO:0001701,GO:0043065,GO:0034612,GO:0006309","nucleic acid binding,metal ion binding,endonuclease activity,hydrolase activity,mitochondrion,response to antibiotic,DNA recombination,in utero embryonic development,positive regulation of apoptotic process,response to tumor necrosis factor,apoptotic DNA fragmentation","."]
["EXOG","endo/exonuclease (5'-3'), endonuclease G-like [Source:HGNC Symbol;Acc:3347]","ENSG00000157036","ENSP00000350987",1,"Endonuclease_NS[1]","family-122","ENDOG,EXOG","ENDOG","EXOG[33,27]","diverse","RNA,DNA","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0046872,GO:0004519,GO:0016787,GO:0005743,GO:0005739","nucleic acid binding,metal ion binding,endonuclease activity,hydrolase activity,mitochondrial inner membrane,mitochondrion","."]
["ASH1L","ash1 (absent, small, or homeotic)-like (Drosophila) [Source:HGNC Symbol;Acc:19088]","ENSG00000116539","ENSP00000357330",4,"BAH[1],SET[1],PHD[1],Bromodomain[1]","family-123","ASH1L,SUV39H1,SUV39H2,SETBP1,WHSC1,WHSC1L1","ASH1L","SUV39H1[3,21],SUV39H2[3,20],SETBP1[11,20],WHSC1[10,21],WHSC1L1[10,21]","ncRNA","lincRNA",22541069,".",".",".",".",".",".",".",".","GO:0005515,GO:0008270,GO:0003677,GO:0018024,GO:0003682,GO:0005634,GO:0005737,GO:0005923,GO:0005694,GO:0005794,GO:0006366,GO:0006355,GO:0007267,GO:0006323","protein binding,zinc ion binding,DNA binding,histone-lysine N-methyltransferase activity,chromatin binding,nucleus,cytoplasm,tight junction,chromosome,Golgi apparatus,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,cell-cell signaling,DNA packaging","."]
["TRMT10C","tRNA methyltransferase 10 homolog C (S. cerevisiae) [Source:HGNC Symbol;Acc:26022]","ENSG00000174173","ENSP00000312356",1,"tRNA_m1G_MT[1]","family-124","TRMT10B,TRMT10C,TRMT10A","TRMT10B","TRMT10C[23,18],TRMT10A[25,24]","ncRNA","RNase P ","21857155 This gene encodes the precursor of a subunit of the mitochondrial ribonuclease P, which is involved in 5' processing of mitochondrial tRNAs. The encoded protein may confer RNA-binding capacity to mitochondrial ribonuclease P and may be essential for transcript processing, RNA modification, translation and mitochondrial respiration. [provided by RefSeq, Nov 2012]","nuclease","RNArelated",1,1,".",".","GO:0008033,GO:0000964","tRNA processing,mitochondrial RNA 5'-end processing","GO:0005634,GO:0005739,GO:0005515,GO:0008168,GO:0042645,GO:0008033,GO:0000964","nucleus,mitochondrion,protein binding,methyltransferase activity,mitochondrial nucleoid,tRNA processing,mitochondrial RNA 5'-end processing","."]
["TRMT10A","tRNA methyltransferase 10 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:28403]","ENSG00000145331","ENSP00000423628",1,"tRNA_m1G_MT[1]","family-124","TRMT10B,TRMT10C,TRMT10A","TRMT10B","TRMT10C[23,18],TRMT10A[25,24]","tRNA","putative tRNA","by homology",".","novel",".",1,".",".",".",".","GO:0008168","methyltransferase activity","."]
["TRMT10B","tRNA methyltransferase 10 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:26454]","ENSG00000165275","ENSP00000366982",1,"tRNA_m1G_MT[1]","family-124","TRMT10B,TRMT10C,TRMT10A","TRMT10B","TRMT10C[23,18],TRMT10A[25,24]","tRNA","putative tRNA","by homology",".",".",".",".",".",".",".",".","GO:0008168","methyltransferase activity","."]
["MRPL33","mitochondrial ribosomal protein L33 [Source:HGNC Symbol;Acc:14487]","ENSG00000243147","ENSP00000296102",1,"Ribosomal_L33[1]","family-125","MRPL33",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0006412","structural constituent of ribosome,mitochondrion,intracellular,ribosome,translation","."]
["SSB","Sjogren syndrome antigen B (autoantigen La) [Source:HGNC Symbol;Acc:11316]","ENSG00000138385","ENSP00000260956",3,"La[1],RRM_1[1],RRM_3[1]","family-126","LARP7,SSB","LARP7","SSB[17,25]","tRNA","tRNA","The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. [provided by RefSeq, Nov 2011]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0000049,GO:0003729,GO:0030529,GO:0006396,GO:0006400,GO:0008334","RNA binding,tRNA binding,mRNA binding,ribonucleoprotein complex,RNA processing,tRNA modification,histone mRNA metabolic process","GO:0000166,GO:0003723,GO:0003676,GO:0000049,GO:0003729,GO:0005634,GO:0030529,GO:0006396,GO:0006400,GO:0008334","nucleotide binding,RNA binding,nucleic acid binding,tRNA binding,mRNA binding,nucleus,ribonucleoprotein complex,RNA processing,tRNA modification,histone mRNA metabolic process","."]
["LARP7","La ribonucleoprotein domain family, member 7 [Source:HGNC Symbol;Acc:24912]","ENSG00000174720","ENSP00000422626",3,"La[1],RRM_1[1],RRM_3[1]","family-126","LARP7,SSB","LARP7","SSB[17,25]","ncRNA","7SK/mRNA","This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0006396","RNA binding,ribonucleoprotein complex,RNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005737,GO:0005654,GO:0030529,GO:0006396","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,cytoplasm,nucleoplasm,ribonucleoprotein complex,RNA processing"," ALAZAMI SYNDROME; ALAZS"]
["MRPL24","mitochondrial ribosomal protein L24 [Source:HGNC Symbol;Acc:14037]","ENSG00000143314","ENSP00000411369",1,"KOW[1]","family-127","MRPL24",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005739","structural constituent of ribosome,intracellular,ribosome,translation,mitochondrion","."]
["RNASEK","ribonuclease, RNase K [Source:HGNC Symbol;Acc:33911]","ENSG00000219200","ENSP00000385440",1,"DUF2650[1]","family-128","RNASEK",".",".","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004521,GO:0009303","endoribonuclease activity,rRNA transcription","GO:0004521,GO:0016021,GO:0009303","endoribonuclease activity,integral to membrane,rRNA transcription","."]
["PELO","pelota homolog (Drosophila) [Source:HGNC Symbol;Acc:8829]","ENSG00000152684","ENSP00000274311",3,"eRF1_1[1],eRF1_2[1],eRF1_3[1]","family-129","PELO",".",".","mRNA","mRNA",20406461,".",".",".",".",".",".",".",".","GO:0046872,GO:0004519,GO:0005634,GO:0005737,GO:0008283,GO:0051301,GO:0007049,GO:0051276","metal ion binding,endonuclease activity,nucleus,cytoplasm,cell proliferation,cell division,cell cycle,chromosome organization","."]
["QARS","glutaminyl-tRNA synthetase [Source:HGNC Symbol;Acc:9751]","ENSG00000172053","ENSP00000307567",4,"tRNA-synt_1c[1],tRNA_synt_1c_R1[1],tRNA-synt_1c_C[1],tRNA_synt_1c_R2[1]","family-13","QARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004819,GO:0006418,GO:0016876,GO:0006412,GO:0043039","aminoacyl-tRNA ligase activity,glutamine-tRNA ligase activity,tRNA aminoacylation for protein translation,ligase activity, forming aminoacyl-tRNA and related compounds,translation,tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004819,GO:0005737,GO:0006418,GO:0006425,GO:0016876,GO:0006412,GO:0043039,GO:0005829,GO:0005759,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,glutamine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,glutaminyl-tRNA aminoacylation,ligase activity, forming aminoacyl-tRNA and related compounds,translation,tRNA aminoacylation,cytosol,mitochondrial matrix,gene expression","."]
["IPO4","importin 4 [Source:HGNC Symbol;Acc:19426]","ENSG00000196497","ENSP00000346453",3,"IBN_N[1],HEAT_2[1],HEAT_EZ[1]","family-130","IPO4",".",".","mRNA","putative mRBP transport","by homology",".",".",".",".",".",".",".",".","GO:0005488,GO:0008536,GO:0005634,GO:0006886,GO:0005515,GO:0005737,GO:0005643,GO:0015031","binding,Ran GTPase binding,nucleus,intracellular protein transport,protein binding,cytoplasm,nuclear pore,protein transport","."]
["CAPRIN1","cell cycle associated protein 1 [Source:HGNC Symbol;Acc:6743]","ENSG00000135387","ENSP00000374296",1,"Caprin-1_C[1]","family-131","CAPRIN1,CAPRIN2","CAPRIN1","CAPRIN2[34,22]","mRNA","mRNA",17210633,"RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0000932,GO:0010494","RNA binding,cytoplasmic mRNA processing body,cytoplasmic stress granule","GO:0003723,GO:0005737,GO:0000932,GO:0010494,GO:0050775,GO:0017148,GO:0061003,GO:0005887,GO:0005829,GO:0030425","RNA binding,cytoplasm,cytoplasmic mRNA processing body,cytoplasmic stress granule,positive regulation of dendrite morphogenesis,negative regulation of translation,positive regulation of dendritic spine morphogenesis,integral to plasma membrane,cytosol,dendrite","."]
["CAPRIN2","caprin family member 2 [Source:HGNC Symbol;Acc:21259]","ENSG00000110888","ENSP00000251071",2,"C1q[1],Caprin-1_C[1]","family-131","CAPRIN1,CAPRIN2","CAPRIN1","CAPRIN2[34,22]","mRNA","putative mRNA",20516077,".",".",".",".",".",".","GO:0003723","RNA binding","GO:0005515,GO:0003723,GO:0005102,GO:0005737,GO:0005739,GO:0043235,GO:0045944,GO:0030308,GO:0032092,GO:0090263,GO:0033138,GO:0050775,GO:0017148,GO:0061003,GO:0000166,GO:0003824,GO:0044237","protein binding,RNA binding,receptor binding,cytoplasm,mitochondrion,receptor complex,positive regulation of transcription from RNA polymerase II promoter,negative regulation of cell growth,positive regulation of protein binding,positive regulation of canonical Wnt signaling pathway,positive regulation of peptidyl-serine phosphorylation,positive regulation of dendrite morphogenesis,negative regulation of translation,positive regulation of dendritic spine morphogenesis,nucleotide binding,catalytic activity,cellular metabolic process","."]
["PNLDC1","poly(A)-specific ribonuclease (PARN)-like domain containing 1 [Source:HGNC Symbol;Acc:21185]","ENSG00000146453","ENSP00000275275",".",".","family-132","PARN,PNLDC1","PARN","PNLDC1[20,25]","mRNA","mRNA","by homology",".",".",".",".",".",".",".",".","GO:0003676,GO:0016021,GO:0005634","nucleic acid binding,integral to membrane,nucleus","."]
["PARN","poly(A)-specific ribonuclease [Source:HGNC Symbol;Acc:8609]","ENSG00000140694","ENSP00000444381",3,"CAF1[2],RNA_bind[1]","family-132","PARN,PNLDC1","PARN","PNLDC1[20,25]","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,".",1,"GO:0003723,GO:0004535,GO:0006402,GO:0003730,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0009451,GO:0000184","RNA binding,poly(A)-specific ribonuclease activity,mRNA catabolic process,mRNA 3'-UTR binding,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,RNA modification,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0003676,GO:0005634,GO:0000166,GO:0003723,GO:0046872,GO:0004535,GO:0005737,GO:0006402,GO:0005515,GO:0019901,GO:0004518,GO:0003730,GO:0005829,GO:0005730,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0007292,GO:0009451,GO:0000184,GO:0090305","nucleic acid binding,nucleus,nucleotide binding,RNA binding,metal ion binding,poly(A)-specific ribonuclease activity,cytoplasm,mRNA catabolic process,protein binding,protein kinase binding,nuclease activity,mRNA 3'-UTR binding,cytosol,nucleolus,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,female gamete generation,RNA modification,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,nucleic acid phosphodiester bond hydrolysis","."]
["TIAL1","TIA1 cytotoxic granule-associated RNA binding protein-like 1 [Source:HGNC Symbol;Acc:11804]","ENSG00000151923","ENSP00000394902",3,"RRM_1[3]","family-133","TIA1,TIAL1","TIA1","TIAL1[77,76]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0017091,GO:0010494","RNA binding,AU-rich element binding,cytoplasmic stress granule","GO:0000166,GO:0003676,GO:0003723,GO:0017091,GO:0005634,GO:0005737,GO:0005764,GO:0010494,GO:0006915,GO:0008284,GO:0006357,GO:0006952,GO:0007281,GO:0017145,GO:0005515","nucleotide binding,nucleic acid binding,RNA binding,AU-rich element binding,nucleus,cytoplasm,lysosome,cytoplasmic stress granule,apoptotic process,positive regulation of cell proliferation,regulation of transcription from RNA polymerase II promoter,defense response,germ cell development,stem cell division,protein binding","."]
["TIA1","TIA1 cytotoxic granule-associated RNA binding protein [Source:HGNC Symbol;Acc:11802]","ENSG00000116001","ENSP00000282574",3,"RRM_1[3]","family-133","TIA1,TIAL1","TIA1","TIAL1[77,76]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0017091,GO:0010494,GO:0008143,GO:0048024","AU-rich element binding,cytoplasmic stress granule,poly(A) RNA binding,regulation of mRNA splicing, via spliceosome","GO:0003676,GO:0000166,GO:0017091,GO:0005634,GO:0010494,GO:0017148,GO:0042036,GO:0005515,GO:0008143,GO:0006915,GO:0048024,GO:0005737","nucleic acid binding,nucleotide binding,AU-rich element binding,nucleus,cytoplasmic stress granule,negative regulation of translation,negative regulation of cytokine biosynthetic process,protein binding,poly(A) RNA binding,apoptotic process,regulation of mRNA splicing, via spliceosome,cytoplasm"," WELANDER DISTAL MYOPATHY; WDM"]
["CDC40","cell division cycle 40 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17350]","ENSG00000168438","ENSP00000357928",5,"WD40[5]","family-134","CDC40,WDR25","CDC40","WDR25[19,20]","mRNA","mRNA","Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]",".","RNArelated",".",1,".",".","GO:0005681,GO:0071013,GO:0008380,GO:0000398,GO:0006406,GO:0031124","spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0005515,GO:0005654,GO:0005681,GO:0071013,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","protein binding,nucleoplasm,spliceosomal complex,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["ZNF598","zinc finger protein 598 [Source:HGNC Symbol;Acc:28079]","ENSG00000167962","ENSP00000455882",".",".","family-135","ZNF598",".",".","mRNA","mRNA",22751931,"candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0005515,GO:0008270,GO:0046872,GO:0005634,GO:0006355","protein binding,zinc ion binding,metal ion binding,nucleus,regulation of transcription, DNA-dependent","."]
["RCL1","RNA terminal phosphate cyclase-like 1 [Source:HGNC Symbol;Acc:17687]","ENSG00000120158","ENSP00000412000",1,"RTC_insert[1]","family-136","RCL1,RTCA","RCL1","RTCA[24,23]","rRNA","rRNA",10790377,".",".",".",".",".",".","GO:0042254,GO:0006396,GO:0003963","ribosome biogenesis,RNA processing,RNA-3'-phosphate cyclase activity","GO:0003824,GO:0005730,GO:0042254,GO:0006396,GO:0003963","catalytic activity,nucleolus,ribosome biogenesis,RNA processing,RNA-3'-phosphate cyclase activity","."]
["RTCA","RNA 3'-terminal phosphate cyclase [Source:HGNC Symbol;Acc:17981]","ENSG00000137996","ENSP00000359146",1,"RTC[1]","family-136","RCL1,RTCA","RCL1","RTCA[24,23]","tRNA","putative tRNA / snoRNA",19690099,".","RNAbinding",".",1,".",".","GO:0006396,GO:0003723,GO:0003963","RNA processing,RNA binding,RNA-3'-phosphate cyclase activity","GO:0003824,GO:0006396,GO:0003723,GO:0005524,GO:0003963,GO:0005634,GO:0005654","catalytic activity,RNA processing,RNA binding,ATP binding,RNA-3'-phosphate cyclase activity,nucleus,nucleoplasm","."]
["MRPL38","mitochondrial ribosomal protein L38 [Source:HGNC Symbol;Acc:14033]","ENSG00000204316","ENSP00000308275",1,"PBP[1]","family-137","PEBP1,PEBP4,MRPL38","PEBP1","PEBP4[29,24],MRPL38[30,15]","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840,GO:0005737,GO:0015629","mitochondrion,ribosome,cytoplasm,actin cytoskeleton","."]
["ADAT2","adenosine deaminase, tRNA-specific 2 [Source:HGNC Symbol;Acc:21172]","ENSG00000189007","ENSP00000237283",1,"dCMP_cyt_deam_1[1]","family-138","ADAT2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0008270,GO:0003824,GO:0016787,GO:0008033","zinc ion binding,catalytic activity,hydrolase activity,tRNA processing","."]
["BOP1","block of proliferation 1 [Source:HGNC Symbol;Acc:15519]","ENSG00000261236","ENSP00000455106",4,"BOP1NT[1],WD40[3]","family-139","BOP1",".",".","rRNA","rRNA","established RBP ",".","RNArelated",".",1,1,".","GO:0006364,GO:0043021,GO:0030529,GO:0030687,GO:0042254,GO:0000463,GO:0000466","rRNA processing,ribonucleoprotein complex binding,ribonucleoprotein complex,preribosome, large subunit precursor,ribosome biogenesis,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0006364,GO:0005515,GO:0043021,GO:0005730,GO:0005654,GO:0030529,GO:0030687,GO:0070545,GO:0008283,GO:0042254,GO:0051726,GO:0000463,GO:0000466","rRNA processing,protein binding,ribonucleoprotein complex binding,nucleolus,nucleoplasm,ribonucleoprotein complex,preribosome, large subunit precursor,PeBoW complex,cell proliferation,ribosome biogenesis,regulation of cell cycle,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["U2SURP","U2 snRNP-associated SURP domain containing [Source:HGNC Symbol;Acc:30855]","ENSG00000163714","ENSP00000422011",4,"cwf21[1],RRM_1[1],Surp[1],CTK3[1]","family-14","U2SURP",".",".","snRNA","snRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0006396,GO:0003676","nucleotide binding,RNA binding,protein binding,nucleus,RNA processing,nucleic acid binding","."]
["DUS3L","dihydrouridine synthase 3-like (S. cerevisiae) [Source:HGNC Symbol;Acc:26920]","ENSG00000141994","ENSP00000311977",2,"Dus[1],zf-CCCH[1]","family-140","DUS3L",".",".","tRNA","putative tRNA","by homology","candidate mRNA binder",".",".",1,".",1,"GO:0017150,GO:0008033","tRNA dihydrouridine synthase activity,tRNA processing","GO:0050660,GO:0017150,GO:0055114,GO:0008033,GO:0046872","flavin adenine dinucleotide binding,tRNA dihydrouridine synthase activity,oxidation-reduction process,tRNA processing,metal ion binding","."]
["CSTF3","cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa [Source:HGNC Symbol;Acc:2485]","ENSG00000176102","ENSP00000315791",2,"Suf[1],TPR_16[1]","family-141","CSTF3",".",".","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0003723,GO:0008380,GO:0000398,GO:0006379,GO:0031124,GO:0006378,GO:0006396,GO:0006397","RNA binding,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation,RNA processing,mRNA processing","GO:0003723,GO:0005634,GO:0005654,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006379,GO:0031124,GO:0006378,GO:0006369,GO:0005622,GO:0006396,GO:0006397","RNA binding,nucleus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription,intracellular,RNA processing,mRNA processing","."]
["SRSF11","serine/arginine-rich splicing factor 11 [Source:HGNC Symbol;Acc:10782]","ENSG00000116754","ENSP00000378568",1,"RRM_1[1]","family-142","SREK1,SRSF11","SREK1","SRSF11[34,44]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["SREK1","splicing regulatory glutamine/lysine-rich protein 1 [Source:HGNC Symbol;Acc:17882]","ENSG00000153914","ENSP00000334538",2,"RRM_1[1],RRM_6[1]","family-142","SREK1,SRSF11","SREK1","SRSF11[34,44]","mRNA","mRNA","This gene encodes a member of a family of serine/arginine-rich (SR) splicing proteins containing RNA recognition motif (RRM) domains. The encoded protein interacts with other SR proteins to modulate splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]","RNAbinding",".",".",1,".",1,"GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0005634,GO:0005739,GO:0043231,GO:0005681,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,nucleus,mitochondrion,intracellular membrane-bounded organelle,spliceosomal complex,mRNA processing,RNA splicing","."]
["POLR1E","polymerase (RNA) I polypeptide E, 53kDa [Source:HGNC Symbol;Acc:17631]","ENSG00000137054","ENSP00000367029",1,"RNA_pol_I_A49[1]","family-143","POLR1E",".",".","rRNA","rRNA","Pol I complex",".",".",".",".",1,".","GO:0009303","rRNA transcription","GO:0003677,GO:0003899,GO:0005634,GO:0006351,GO:0005737,GO:0030054,GO:0005730,GO:0009303,GO:0005515","DNA binding,DNA-directed RNA polymerase activity,nucleus,transcription, DNA-templated,cytoplasm,cell junction,nucleolus,rRNA transcription,protein binding","."]
["EXOSC7","exosome component 7 [Source:HGNC Symbol;Acc:28112]","ENSG00000075914","ENSP00000265564",2,"RNase_PH[1],RNase_PH_C[1]","family-144","EXOSC7,EXOSC8,EXOSC9","EXOSC7","EXOSC8[23,25],EXOSC9[24,15]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000175,GO:0000178,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0006401,GO:0043928","RNA binding,3'-5'-exoribonuclease activity,exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,RNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0000175,GO:0005829,GO:0005730,GO:0000178,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0006401,GO:0043928","RNA binding,protein binding,3'-5'-exoribonuclease activity,cytosol,nucleolus,exosome (RNase complex),gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,RNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["EXOSC8","exosome component 8 [Source:HGNC Symbol;Acc:17035]","ENSG00000120699","ENSP00000374354",2,"RNase_PH[1],RNase_PH_C[1]","family-144","EXOSC7,EXOSC8,EXOSC9","EXOSC7","EXOSC8[23,25],EXOSC9[24,15]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0017091,GO:0000178,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","AU-rich element binding,exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0005515,GO:0017091,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0000178,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","protein binding,AU-rich element binding,nucleus,cytoplasm,cytosol,nucleolus,exosome (RNase complex),gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["EXOSC9","exosome component 9 [Source:HGNC Symbol;Acc:9137]","ENSG00000123737","ENSP00000243498",2,"RNase_PH[1],RNase_PH_C[1]","family-144","EXOSC7,EXOSC8,EXOSC9","EXOSC7","EXOSC8[23,25],EXOSC9[24,15]","diverse","diverse","established RBP ",".","RNAbinding",".",1,1,".","GO:0003723,GO:0017091,GO:0000175,GO:0000178,GO:0000176,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928,GO:0071028,GO:0000956,GO:0071035","RNA binding,AU-rich element binding,3'-5'-exoribonuclease activity,exosome (RNase complex),nuclear exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear mRNA surveillance,nuclear-transcribed mRNA catabolic process,nuclear polyadenylation-dependent rRNA catabolic process","GO:0003723,GO:0005515,GO:0017091,GO:0000175,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0000178,GO:0000176,GO:0006955,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0030307,GO:0043928,GO:0071028,GO:0000956,GO:0071035","RNA binding,protein binding,AU-rich element binding,3'-5'-exoribonuclease activity,nucleus,cytoplasm,cytosol,nucleolus,exosome (RNase complex),nuclear exosome (RNase complex),immune response,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,positive regulation of cell growth,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear mRNA surveillance,nuclear-transcribed mRNA catabolic process,nuclear polyadenylation-dependent rRNA catabolic process","."]
["MRPL12","mitochondrial ribosomal protein L12 [Source:HGNC Symbol;Acc:10378]","ENSG00000262814","ENSP00000333837",1,"Ribosomal_L12[1]","family-145","MRPL12",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0005762,GO:0006412","RNA binding,structural constituent of ribosome,ribosome,mitochondrial large ribosomal subunit,translation","GO:0003723,GO:0005515,GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0005762,GO:0045893,GO:0006412,GO:0006390","RNA binding,protein binding,structural constituent of ribosome,mitochondrion,intracellular,ribosome,mitochondrial large ribosomal subunit,positive regulation of transcription, DNA-dependent,translation,transcription from mitochondrial promoter","."]
["RPS28","ribosomal protein S28 [Source:HGNC Symbol;Acc:10418]","ENSG00000233927","ENSP00000472469",1,"Ribosomal_S28e[1]","family-146","RPS28",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003735,GO:0022627,GO:0005829,GO:0005622,GO:0005840,GO:0015935,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","structural constituent of ribosome,cytosolic small ribosomal subunit,cytosol,intracellular,ribosome,small ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis","."]
["TEFM","transcription elongation factor, mitochondrial [Source:HGNC Symbol;Acc:26223]","ENSG00000172171","ENSP00000462963",1,"HHH_3[1]","family-147","TEFM",".",".","mRNA","putative mRNA",21278163,"candidate mRNA binder","novel",1,1,".",".","GO:0030529","ribonucleoprotein complex","GO:0005515,GO:0003676,GO:0030337,GO:0005759,GO:0030529,GO:0042645,GO:0006355,GO:0006390,GO:0006119","protein binding,nucleic acid binding,DNA polymerase processivity factor activity,mitochondrial matrix,ribonucleoprotein complex,mitochondrial nucleoid,regulation of transcription, DNA-dependent,transcription from mitochondrial promoter,oxidative phosphorylation","."]
["RPL12","ribosomal protein L12 [Source:HGNC Symbol;Acc:10302]","ENSG00000197958","ENSP00000354739",2,"Ribosomal_L11[1],Ribosomal_L11_N[1]","family-148","RPL12",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0005829,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,cytosol,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ZC3H3","zinc finger CCCH-type containing 3 [Source:HGNC Symbol;Acc:28972]","ENSG00000014164","ENSP00000262577",3,"zf-CCCH[3]","family-149","ZC3H3",".",".","mRNA","mRNA",19364924,".",".",".",".",".",1,"GO:0016973,GO:0006378,GO:0010793","poly(A)+ mRNA export from nucleus,mRNA polyadenylation,regulation of mRNA export from nucleus","GO:0046872,GO:0005634,GO:0016973,GO:0006378,GO:0010793","metal ion binding,nucleus,poly(A)+ mRNA export from nucleus,mRNA polyadenylation,regulation of mRNA export from nucleus","."]
["EIF6","eukaryotic translation initiation factor 6 [Source:HGNC Symbol;Acc:6159]","ENSG00000242372","ENSP00000363574",1,"eIF-6[1]","family-15","EIF6",".",".","mRNA","putative mRNA","The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]",".",".",".",".",".",".","GO:0043022,GO:0042256,GO:0003743","ribosome binding,mature ribosome assembly,translation initiation factor activity","GO:0043022,GO:0005638,GO:0042256,GO:0005515,GO:0003743,GO:0005882,GO:0005634,GO:0005737","ribosome binding,lamin filament,mature ribosome assembly,protein binding,translation initiation factor activity,intermediate filament,nucleus,cytoplasm","."]
["NELFE","negative elongation factor complex member E [Source:HGNC Symbol;Acc:13974]","ENSG00000206268","ENSP00000407528",1,"RRM_1[1]","family-150","NELFE",".",".","mRNA","mRNA","18303858, The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins; however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. [provided by RefSeq, Jul 2008]",".","experimentally validated",".",1,".",1,"GO:0003723,GO:0003746","RNA binding,translation elongation factor activity","GO:0005634,GO:0005739,GO:0034244,GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005654,GO:0032021,GO:0006366,GO:0016032,GO:0010467,GO:0006368,GO:0050434,GO:0003746","nucleus,mitochondrion,negative regulation of transcription elongation from RNA polymerase II promoter,nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleoplasm,NELF complex,transcription from RNA polymerase II promoter,viral process,gene expression,transcription elongation from RNA polymerase II promoter,positive regulation of viral transcription,translation elongation factor activity","."]
["EIF2B3","eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa [Source:HGNC Symbol;Acc:3259] [Type: protein coding Ensembl/Havana merge]","ENSG00000070785","ENSP00000353575",1,"NTP_transferase[1]","family-151","EIF2B3",".",".","mRNA","putative mRNA","eiF2B complex",".",".",".",".",".",".","GO:0003743,GO:0008135,GO:0005851,GO:0006412,GO:0006413,GO:0006417","translation initiation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 2B complex,translation,translational initiation,regulation of translation","GO:0016779,GO:0009058,GO:0005515,GO:0005085,GO:0003743,GO:0008135,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0014003,GO:0010467,GO:0009749,GO:0009408,GO:0044267,GO:0043434,GO:0032057,GO:0006413,GO:0051716,GO:0006417","nucleotidyltransferase activity,biosynthetic process,protein binding,guanyl-nucleotide exchange factor activity,translation initiation factor activity,translation factor activity, nucleic acid binding,cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex,translation,oligodendrocyte development,gene expression,response to glucose,response to heat,cellular protein metabolic process,response to peptide hormone,negative regulation of translational initiation in response to stress,translational initiation,cellular response to stimulus,regulation of translation"," LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER; VWM"]
["APOBEC2","apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 [Source:HGNC Symbol;Acc:605]","ENSG00000124701","ENSP00000244669",1,"APOBEC_N[1]","family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","AICDA","APOBEC2[29,26],APOBEC3D[36,18],APOBEC3F[38,20],APOBEC1[28,23],APOBEC3C[39,41],APOBEC3B[39,20],APOBEC3H[33,33],APOBEC3G[40,21],APOBEC3A[39,39]","mRNA","mRNA",17187054,".",".",".",".",".",".","GO:0003723,GO:0006397,GO:0016556","RNA binding,mRNA processing,mRNA modification","GO:0003723,GO:0008270,GO:0003824,GO:0016814,GO:0004126,GO:0006397,GO:0080111,GO:0009972,GO:0016556","RNA binding,zinc ion binding,catalytic activity,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,cytidine deaminase activity,mRNA processing,DNA demethylation,cytidine deamination,mRNA modification","."]
["APOBEC3H","apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H [Source:HGNC Symbol;Acc:24100]","ENSG00000100298","ENSP00000216123",1,"APOBEC_N[1]","family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","AICDA","APOBEC2[29,26],APOBEC3D[36,18],APOBEC3F[38,20],APOBEC1[28,23],APOBEC3C[39,41],APOBEC3B[39,20],APOBEC3H[33,33],APOBEC3G[40,21],APOBEC3A[39,39]","ncRNA","7SL, viral RNA",22859935,".",".",".",".",1,".","GO:0000932","cytoplasmic mRNA processing body","GO:0005515,GO:0008270,GO:0003824,GO:0016787,GO:0016814,GO:0004126,GO:0005634,GO:0005737,GO:0000932,GO:0045087,GO:0051607,GO:0009972,GO:0010529,GO:0070383,GO:0045869,GO:0048525","protein binding,zinc ion binding,catalytic activity,hydrolase activity,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,cytidine deaminase activity,nucleus,cytoplasm,cytoplasmic mRNA processing body,innate immune response,defense response to virus,cytidine deamination,negative regulation of transposition,DNA cytosine deamination,negative regulation of single stranded viral RNA replication via double stranded DNA intermediate,negative regulation of viral process","."]
["APOBEC3F","apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F [Source:HGNC Symbol;Acc:17356]","ENSG00000128394","ENSP00000309749",2,"APOBEC_N[2]","family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","AICDA","APOBEC2[29,26],APOBEC3D[36,18],APOBEC3F[38,20],APOBEC1[28,23],APOBEC3C[39,41],APOBEC3B[39,20],APOBEC3H[33,33],APOBEC3G[40,21],APOBEC3A[39,39]","mRNA","mRNA, DNA",24651717,"RNAmod",".",".",1,".",".","GO:0003723,GO:0000932,GO:0030529,GO:0030895","RNA binding,cytoplasmic mRNA processing body,ribonucleoprotein complex,apolipoprotein B mRNA editing enzyme complex","GO:0003723,GO:0005515,GO:0008270,GO:0016814,GO:0004126,GO:0005737,GO:0000932,GO:0030529,GO:0030895,GO:0045087,GO:0045071,GO:0002230,GO:0051607,GO:0080111,GO:0009972,GO:0010529,GO:0070383,GO:0045869,GO:0016553,GO:0048525,GO:0003824","RNA binding,protein binding,zinc ion binding,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,cytidine deaminase activity,cytoplasm,cytoplasmic mRNA processing body,ribonucleoprotein complex,apolipoprotein B mRNA editing enzyme complex,innate immune response,negative regulation of viral genome replication,positive regulation of defense response to virus by host,defense response to virus,DNA demethylation,cytidine deamination,negative regulation of transposition,DNA cytosine deamination,negative regulation of single stranded viral RNA replication via double stranded DNA intermediate,base conversion or substitution editing,negative regulation of viral process,catalytic activity","."]
["APOBEC3G","apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G [Source:HGNC Symbol;Acc:17357]","ENSG00000239713","ENSP00000385057",2,"APOBEC_N[2]","family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","AICDA","APOBEC2[29,26],APOBEC3D[36,18],APOBEC3F[38,20],APOBEC1[28,23],APOBEC3C[39,41],APOBEC3B[39,20],APOBEC3H[33,33],APOBEC3G[40,21],APOBEC3A[39,39]","mRNA","mRNA, DNA"," 16887808, 24651717",".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0030529,GO:0030895","RNA binding,cytoplasmic mRNA processing body,ribonucleoprotein complex,apolipoprotein B mRNA editing enzyme complex","GO:0003723,GO:0005515,GO:0042803,GO:0008270,GO:0003824,GO:0016814,GO:0004126,GO:0047844,GO:0005737,GO:0005739,GO:0005829,GO:0000932,GO:0030529,GO:0030895,GO:0045087,GO:0016032,GO:0045071,GO:0002230,GO:0051607,GO:0019048,GO:0009972,GO:0010529,GO:0070383,GO:0045869,GO:0016553,GO:0048525","RNA binding,protein binding,protein homodimerization activity,zinc ion binding,catalytic activity,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,cytidine deaminase activity,deoxycytidine deaminase activity,cytoplasm,mitochondrion,cytosol,cytoplasmic mRNA processing body,ribonucleoprotein complex,apolipoprotein B mRNA editing enzyme complex,innate immune response,viral process,negative regulation of viral genome replication,positive regulation of defense response to virus by host,defense response to virus,modulation by virus of host morphology or physiology,cytidine deamination,negative regulation of transposition,DNA cytosine deamination,negative regulation of single stranded viral RNA replication via double stranded DNA intermediate,base conversion or substitution editing,negative regulation of viral process","."]
["APOBEC1","apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 [Source:HGNC Symbol;Acc:604]","ENSG00000111701","ENSP00000229304",1,"APOBEC_N[1]","family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","AICDA","APOBEC2[29,26],APOBEC3D[36,18],APOBEC3F[38,20],APOBEC1[28,23],APOBEC3C[39,41],APOBEC3B[39,20],APOBEC3H[33,33],APOBEC3G[40,21],APOBEC3A[39,39]","mRNA","mRNA","This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0017091,GO:0016556,GO:0006397,GO:0006396,GO:0048255","RNA binding,AU-rich element binding,mRNA modification,mRNA processing,RNA processing,mRNA stabilization","GO:0005515,GO:0003723,GO:0008270,GO:0003824,GO:0016814,GO:0017091,GO:0004126,GO:0005737,GO:0005654,GO:0042157,GO:0080111,GO:0090310,GO:0016554,GO:0016556,GO:0006629,GO:0042493,GO:0010467,GO:0042127,GO:0006397,GO:0006396,GO:0042953,GO:0006970,GO:0032869,GO:0010043,GO:0010332,GO:0045471,GO:0051607,GO:0051592,GO:0042158,GO:0048255,GO:0009972","protein binding,RNA binding,zinc ion binding,catalytic activity,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,AU-rich element binding,cytidine deaminase activity,cytoplasm,nucleoplasm,lipoprotein metabolic process,DNA demethylation,negative regulation of methylation-dependent chromatin silencing,cytidine to uridine editing,mRNA modification,lipid metabolic process,response to drug,gene expression,regulation of cell proliferation,mRNA processing,RNA processing,lipoprotein transport,response to osmotic stress,cellular response to insulin stimulus,response to zinc ion,response to gamma radiation,response to ethanol,defense response to virus,response to calcium ion,lipoprotein biosynthetic process,mRNA stabilization,cytidine deamination","."]
["ZC3H7A","zinc finger CCCH-type containing 7A [Source:HGNC Symbol;Acc:30959]","ENSG00000122299","ENSP00000347999",3,"TPR_11[1],zf-C2H2_jaz[1],zf-CCCH[1]","family-153","ZC3H7A,ZC3H7B","ZC3H7A","ZC3H7B[45,45]","unknown","unknown","by homology","RNAbinding","novel",1,1,".",1,".",".","GO:0046872,GO:0005634","metal ion binding,nucleus","."]
["ZC3H7B","zinc finger CCCH-type containing 7B [Source:HGNC Symbol;Acc:30869]","ENSG00000100403","ENSP00000263243",4,"TPR_11[1],zf-C2H2_jaz[1],zf-CCCH[2]","family-153","ZC3H7A,ZC3H7B","ZC3H7A","ZC3H7B[45,45]","unknown","unknown","by homology","candidate mRNA binder","experimentally validated",1,1,".",1,".",".","GO:0005515,GO:0046872,GO:0005634,GO:0019048","protein binding,metal ion binding,nucleus,modulation by virus of host morphology or physiology","."]
["NOP9","NOP9 nucleolar protein homolog (yeast) [Source:HGNC Symbol;Acc:19826]","ENSG00000196943","ENSP00000267425",".",".","family-154","NOP9",".",".","rRNA","putative rRNA",1795697,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0005488,GO:0003723","binding,RNA binding","."]
["PQBP1","polyglutamine binding protein 1 [Source:HGNC Symbol;Acc:9330]","ENSG00000102103","ENSP00000218224",1,"WW[1]","family-155","PQBP1",".",".","mRNA","putative mRNA",16162498,".",".",".",".",1,".","GO:0010494,GO:0071598","cytoplasmic stress granule,neuronal ribonucleoprotein granule","GO:0003677,GO:0003713,GO:0005634,GO:0005737,GO:0010494,GO:0071598,GO:0006351,GO:0006355,GO:0005515,GO:0034063","DNA binding,transcription coactivator activity,nucleus,cytoplasm,cytoplasmic stress granule,neuronal ribonucleoprotein granule,transcription, DNA-templated,regulation of transcription, DNA-dependent,protein binding,stress granule assembly"," RENPENNING SYNDROME 1; RENS1"]
["PATL2","protein associated with topoisomerase II homolog 2 (yeast) [Source:HGNC Symbol;Acc:33630]","ENSG00000229474","ENSP00000416673",1,"PAT1[1]","family-156","PATL1,PATL2","PATL1","PATL2[23,33]","mRNA","mRNA",17936923,".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0030529,GO:0010607","RNA binding,cytoplasmic mRNA processing body,ribonucleoprotein complex,negative regulation of cytoplasmic mRNA processing body assembly","GO:0003723,GO:0005515,GO:0005737,GO:0005634,GO:0000932,GO:0030529,GO:0017148,GO:0010607","RNA binding,protein binding,cytoplasm,nucleus,cytoplasmic mRNA processing body,ribonucleoprotein complex,negative regulation of translation,negative regulation of cytoplasmic mRNA processing body assembly","."]
["PATL1","protein associated with topoisomerase II homolog 1 (yeast) [Source:HGNC Symbol;Acc:26721]","ENSG00000166889","ENSP00000300146",1,"PAT1[1]","family-156","PATL1,PATL2","PATL1","PATL2[23,33]","mRNA","mRNA",20852261,"RNAbinding","experimentally validated",1,1,".",".","GO:0003723,GO:0034046,GO:0008266,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000290,GO:0033962,GO:0043928","RNA binding,poly(G) RNA binding,poly(U) RNA binding,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0034046,GO:0008266,GO:0005829,GO:0000932,GO:0043231,GO:0016605,GO:0030014,GO:0016607,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000290,GO:0033962,GO:0043928","RNA binding,protein binding,poly(G) RNA binding,poly(U) RNA binding,cytosol,cytoplasmic mRNA processing body,intracellular membrane-bounded organelle,PML body,CCR4-NOT complex,nuclear speck,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["EDC3","enhancer of mRNA decapping 3 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26114]","ENSG00000179151","ENSP00000455580",2,"LSM14[1],YjeF_N[1]","family-157","EDC3",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0043928","RNA binding,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0042802,GO:0005829,GO:0000932,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0043928","RNA binding,protein binding,identical protein binding,cytosol,cytoplasmic mRNA processing body,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["WBP4","WW domain binding protein 4 [Source:HGNC Symbol;Acc:12739]","ENSG00000120688","ENSP00000439301",3,"WW[2],zf-U1[1]","family-158","WBP4",".",".","mRNA","mRNA","This gene encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0005681,GO:0045292","spliceosomal complex,mRNA cis splicing, via spliceosome","GO:0005515,GO:0008270,GO:0003676,GO:0070064,GO:0005634,GO:0005886,GO:0005681,GO:0016607,GO:0045292","protein binding,zinc ion binding,nucleic acid binding,proline-rich region binding,nucleus,plasma membrane,spliceosomal complex,nuclear speck,mRNA cis splicing, via spliceosome","."]
["GLTSCR2","glioma tumor suppressor candidate region gene 2 [Source:HGNC Symbol;Acc:4333]","ENSG00000105373","ENSP00000470263",2,"Nop53[1],DUF4081[1]","family-159","GLTSCR2",".",".","rRNA","putative rRNA",15686447,"candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005622,GO:0043231,GO:0005730","intracellular,intracellular membrane-bounded organelle,nucleolus","."]
["RPS18","ribosomal protein S18 [Source:HGNC Symbol;Acc:10401]","ENSG00000226225","ENSP00000403175",1,"Ribosomal_S13[1]","family-16","RPS18",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003723,GO:0003735,GO:0022627,GO:0005840,GO:0006412,GO:0019843,GO:0015935,GO:0042254,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,translation,rRNA binding,small ribosomal subunit,ribosome biogenesis,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003676,GO:0003735,GO:0005622,GO:0022627,GO:0005840,GO:0005581,GO:0006412,GO:0019843,GO:0005829,GO:0015935,GO:0042254,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,nucleic acid binding,structural constituent of ribosome,intracellular,cytosolic small ribosomal subunit,ribosome,collagen,translation,rRNA binding,cytosol,small ribosomal subunit,ribosome biogenesis,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ASCC1","activating signal cointegrator 1 complex subunit 1 [Source:HGNC Symbol;Acc:24268]","ENSG00000138303","ENSP00000378373",2,"AKAP7_NLS[1],KH_1[1]","family-160","ASCC1",".",".","unknown","unknown","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0003824,GO:0005667,GO:0005737,GO:0006351,GO:0006355","RNA binding,catalytic activity,transcription factor complex,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent"," BARRETT ESOPHAGUS"]
["EIF5A","eukaryotic translation initiation factor 5A [Source:HGNC Symbol;Acc:3300]","ENSG00000132507","ENSP00000460284",2,"KOW[1],eIF-5a[1]","family-161","EIF5A,EIF5AL1,EIF5A2","EIF5A","EIF5AL1[82,98],EIF5A2[68,82]","mRNA","mRNA",24220243,"translationfactor",".",".",1,".",".","GO:0003723,GO:0043022,GO:0003746,GO:0017070,GO:0006406,GO:0006452,GO:0045901,GO:0045905","RNA binding,ribosome binding,translation elongation factor activity,U6 snRNA binding,mRNA export from nucleus,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination","GO:0003723,GO:0005515,GO:0043022,GO:0003746,GO:0047485,GO:0017070,GO:0005634,GO:0005737,GO:0005789,GO:0005829,GO:0005643,GO:0005642,GO:0006915,GO:0006611,GO:0008284,GO:0006406,GO:0008612,GO:0044267,GO:0006913,GO:0043687,GO:0006452,GO:0045901,GO:0045905","RNA binding,protein binding,ribosome binding,translation elongation factor activity,protein N-terminus binding,U6 snRNA binding,nucleus,cytoplasm,endoplasmic reticulum membrane,cytosol,nuclear pore,annulate lamellae,apoptotic process,protein export from nucleus,positive regulation of cell proliferation,mRNA export from nucleus,peptidyl-lysine modification to hypusine,cellular protein metabolic process,nucleocytoplasmic transport,post-translational protein modification,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination","."]
["EIF5A2","eukaryotic translation initiation factor 5A2 [Source:HGNC Symbol;Acc:3301]","ENSG00000163577","ENSP00000417133",2,"KOW[1],eIF-5a[1]","family-161","EIF5A,EIF5AL1,EIF5A2","EIF5A","EIF5AL1[82,98],EIF5A2[68,82]","mRNA","putative mRNA","by homology",".",".",".",".",1,".","GO:0003723,GO:0043022,GO:0003746,GO:0006452,GO:0045901,GO:0045905,GO:0051028","RNA binding,ribosome binding,translation elongation factor activity,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination,mRNA transport","GO:0003723,GO:0043022,GO:0003746,GO:0008612,GO:0006452,GO:0045901,GO:0045905,GO:0005515,GO:0005789,GO:0005829,GO:0005643,GO:0007283,GO:0015031,GO:0008284,GO:0051028,GO:0044267,GO:0043687,GO:0010509","RNA binding,ribosome binding,translation elongation factor activity,peptidyl-lysine modification to hypusine,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination,protein binding,endoplasmic reticulum membrane,cytosol,nuclear pore,spermatogenesis,protein transport,positive regulation of cell proliferation,mRNA transport,cellular protein metabolic process,post-translational protein modification,polyamine homeostasis","."]
["EIF5AL1","eukaryotic translation initiation factor 5A-like 1 [Source:HGNC Symbol;Acc:17419]","ENSG00000253626","ENSP00000430706",1,"eIF-5a[1]","family-161","EIF5A,EIF5AL1,EIF5A2","EIF5A","EIF5AL1[82,98],EIF5A2[68,82]","mRNA","putative mRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0043022,GO:0003746,GO:0051028,GO:0006452,GO:0045901,GO:0045905","RNA binding,ribosome binding,translation elongation factor activity,mRNA transport,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination","GO:0003723,GO:0043022,GO:0003746,GO:0005789,GO:0005643,GO:0043025,GO:0030425,GO:0043066,GO:0015031,GO:0007568,GO:0051028,GO:0008612,GO:0006452,GO:0045901,GO:0045905,GO:0051149","RNA binding,ribosome binding,translation elongation factor activity,endoplasmic reticulum membrane,nuclear pore,neuronal cell body,dendrite,negative regulation of apoptotic process,protein transport,aging,mRNA transport,peptidyl-lysine modification to hypusine,translational frameshifting,positive regulation of translational elongation,positive regulation of translational termination,positive regulation of muscle cell differentiation","."]
["MRPL47","mitochondrial ribosomal protein L47 [Source:HGNC Symbol;Acc:16652]","ENSG00000136522","ENSP00000376427",1,"MRP-L47[1]","family-162","MRPL47",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrial ribosome,translation","GO:0003735,GO:0005761,GO:0006412,GO:0005739","structural constituent of ribosome,mitochondrial ribosome,translation,mitochondrion","."]
["BOLL","bol, boule-like (Drosophila) [Source:HGNC Symbol;Acc:14273]","ENSG00000152430","ENSP00000397711",1,"RRM_1[1]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0008494,GO:0045948","RNA binding,translation activator activity,positive regulation of translational initiation","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0008494,GO:0005737,GO:0030154,GO:0007275,GO:0007283,GO:0007126,GO:0045948","nucleotide binding,RNA binding,protein binding,nucleic acid binding,translation activator activity,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis,meiosis,positive regulation of translational initiation","."]
["DAZL","deleted in azoospermia-like [Source:HGNC Symbol;Acc:2685]","ENSG00000092345","ENSP00000398109",1,"RRM_1[1]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,"GO:0003723,GO:0008494,GO:0045948,GO:0003730","RNA binding,translation activator activity,positive regulation of translational initiation,mRNA 3'-UTR binding","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0008494,GO:0005634,GO:0005737,GO:0007275,GO:0007283,GO:0007281,GO:0045948,GO:0042802,GO:0003730,GO:0005844,GO:0045836","nucleotide binding,nucleic acid binding,RNA binding,protein binding,translation activator activity,nucleus,cytoplasm,multicellular organismal development,spermatogenesis,germ cell development,positive regulation of translational initiation,identical protein binding,mRNA 3'-UTR binding,polysome,positive regulation of meiosis","."]
["DAZ1","deleted in azoospermia 1 [Source:HGNC Symbol;Acc:2682]","ENSG00000188120","ENSP00000371950",3,"RRM_1[3]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0008494,GO:0045948","RNA binding,translation activator activity,positive regulation of translational initiation","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0030154,GO:0007275,GO:0007283,GO:0005515,GO:0008494,GO:0045948","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis,protein binding,translation activator activity,positive regulation of translational initiation"," SPERMATOGENIC FAILURE, Y-LINKED, 2; SPGFY2"]
["DAZ2","deleted in azoospermia 2 [Source:HGNC Symbol;Acc:15964]","ENSG00000205944","ENSP00000371871",1,"RRM_1[1]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0030154,GO:0007275,GO:0007283,GO:0007338","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis,single fertilization"," SPERMATOGENIC FAILURE, Y-LINKED, 2; SPGFY2"]
["DAZ3","deleted in azoospermia 3 [Source:HGNC Symbol;Acc:15965]","ENSG00000187191","ENSP00000401049",1,"RRM_1[1]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0030154,GO:0007275,GO:0007283","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis"," SPERMATOGENIC FAILURE, Y-LINKED, 2; SPGFY2"]
["DAZ4","deleted in azoospermia 4 [Source:HGNC Symbol;Acc:15966]","ENSG00000205916","ENSP00000401363",2,"RRM_1[2]","family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","DAZ1","DAZ3[53,90],DAZ4[78,100],DAZ2[52,60],DAZL[24,56],BOLL[9,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0030154,GO:0007275,GO:0007283","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis"," SPERMATOGENIC FAILURE, Y-LINKED, 2; SPGFY2"]
["INTS1","integrator complex subunit 1 [Source:HGNC Symbol;Acc:24555]","ENSG00000164880","ENSP00000385722",1,"DUF3677[1]","family-164","INTS1",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180,GO:0034474","integrator complex,snRNA processing,U2 snRNA 3'-end processing","GO:0005488,GO:0005634,GO:0016021,GO:0031965,GO:0032039,GO:0001832,GO:0043066,GO:0043154,GO:0001833,GO:0016180,GO:0034474","binding,nucleus,integral to membrane,nuclear membrane,integrator complex,blastocyst growth,negative regulation of apoptotic process,negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,inner cell mass cell proliferation,snRNA processing,U2 snRNA 3'-end processing","."]
["RPLP1","ribosomal protein, large, P1 [Source:HGNC Symbol;Acc:10372]","ENSG00000137818","ENSP00000346037",1,"Ribosomal_60s[1]","family-165","RPLP1",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0005737,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,cytoplasm,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["MRPS11","mitochondrial ribosomal protein S11 [Source:HGNC Symbol;Acc:14050]","ENSG00000181991","ENSP00000317376",1,"Ribosomal_S11[1]","family-166","MRPS11",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005840,GO:0005763,GO:0006412,GO:0042769,GO:0005739","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation,DNA damage response, detection of DNA damage,mitochondrion","."]
["WDR43","WD repeat domain 43 [Source:HGNC Symbol;Acc:28945]","ENSG00000163811","ENSP00000384302",3,"Utp12[1],WD40[2]","family-167","WDR43",".",".","rRNA","U3 snoRNA/ rRNA","UTP5 Subunit of U3-containing Small Subunit (SSU) processome complex involved in production of 18S rRNA and assembly of small ribosomal subunit [Source: SGD; acc: S000002806]",".","novel",".",1,1,".",".",".","GO:0005488,GO:0005515,GO:0005730","binding,protein binding,nucleolus","."]
["TRMT112","tRNA methyltransferase 11-2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26940]","ENSG00000173113","ENSP00000309433",1,"Trm112p[1]","family-168","TRMT112",".",".","tRNA","putative tRNA","Catalytic subunit of adoMet-dependent tRNA methyltransferase complex; required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain; another complex member is Trm112p",".",".",".",".",".",".",".",".","GO:0005515,GO:0008276,GO:0043234,GO:0018364","protein binding,protein methyltransferase activity,protein complex,peptidyl-glutamine methylation","."]
["PPP1R8","protein phosphatase 1, regulatory subunit 8 [Source:HGNC Symbol;Acc:9296]","ENSG00000117751","ENSP00000311677",1,"FHA[1]","family-169","PPP1R8",".",".","diverse","diverse","10432294, This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0008995,GO:0005681,GO:0006397,GO:0008380,GO:0006401","RNA binding,ribonuclease E activity,spliceosomal complex,mRNA processing,RNA splicing,RNA catabolic process","GO:0003723,GO:0005515,GO:0003677,GO:0004519,GO:0008599,GO:0004865,GO:0008995,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0006351,GO:0008283,GO:0006355,GO:0006397,GO:0008380,GO:0006401","RNA binding,protein binding,DNA binding,endonuclease activity,protein phosphatase type 1 regulator activity,protein serine/threonine phosphatase inhibitor activity,ribonuclease E activity,nucleus,cytoplasm,spliceosomal complex,nuclear speck,transcription, DNA-templated,cell proliferation,regulation of transcription, DNA-dependent,mRNA processing,RNA splicing,RNA catabolic process","."]
["FBXO17","F-box protein 17 [Source:HGNC Symbol;Acc:18754]","ENSG00000104835","ENSP00000292852",2,"F-box-like[1],FBA[1]","family-17","FBXO17,FBXO27,NCCRP1,FBXO6,FBXO44,FBXO2","FBXO17","FBXO27[58,57],NCCRP1[25,25],FBXO6[33,31],FBXO44[32,35],FBXO2[36,34]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0030163,GO:0005515,GO:0001948,GO:0019005","protein catabolic process,protein binding,glycoprotein binding,SCF ubiquitin ligase complex","."]
["MTHFSD","methenyltetrahydrofolate synthetase domain containing [Source:HGNC Symbol;Acc:25778]","ENSG00000103248","ENSP00000370612",2,"RRM_1[1],5-FTHF_cyc-lig[1]","family-170","MTHFSD",".",".","mRNA","putative mRNA","by domain","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005524,GO:0003676,GO:0030272,GO:0009396","nucleotide binding,RNA binding,ATP binding,nucleic acid binding,5-formyltetrahydrofolate cyclo-ligase activity,folic acid-containing compound biosynthetic process","."]
["SON","SON DNA binding protein [Source:HGNC Symbol;Acc:11183]","ENSG00000159140","ENSP00000348984",2,"G-patch[1],DND1_DSRM[1]","family-171","SON",".",".","mRNA","mRNA","This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","RNAbinding","experimentally validated",1,1,".",".","GO:0003723,GO:0006397,GO:0008380,GO:0043484","RNA binding,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0003723,GO:0005515,GO:0003676,GO:0003677,GO:0050733,GO:0005634,GO:0016607,GO:0043066,GO:0000910,GO:0006397,GO:0008380,GO:0043484,GO:0051726,GO:0000226","RNA binding,protein binding,nucleic acid binding,DNA binding,RS domain binding,nucleus,nuclear speck,negative regulation of apoptotic process,cytokinesis,mRNA processing,RNA splicing,regulation of RNA splicing,regulation of cell cycle,microtubule cytoskeleton organization","."]
["SPATS2L","spermatogenesis associated, serine-rich 2-like [Source:HGNC Symbol;Acc:24574]","ENSG00000196141","ENSP00000405751",2,"GVQW[1],DUF1387[1]","family-172","SPATS2,SPATS2L","SPATS2","SPATS2L[36,35]","mRNA","putative mRNA/ rRNA",19005571,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005515,GO:0005737,GO:0005730,GO:0043234","protein binding,cytoplasm,nucleolus,protein complex","."]
["SPATS2","spermatogenesis associated, serine-rich 2 [Source:HGNC Symbol;Acc:18650]","ENSG00000123352","ENSP00000326841",1,"DUF1387[1]","family-172","SPATS2,SPATS2L","SPATS2","SPATS2L[36,35]","mRNA","mRNA","by homology",".","novel",".",1,".",".",".",".","GO:0005737,GO:0005515","cytoplasm,protein binding","."]
["MAEL","maelstrom spermatogenic transposon silencer [Source:HGNC Symbol;Acc:25929]","ENSG00000143194","ENSP00000356846",2,"Maelstrom[1],HMG_box_2[1]","family-173","MAEL",".",".","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0071547,GO:0043186,GO:0031047,GO:0034587","piP-body,P granule,gene silencing by RNA,piRNA metabolic process","GO:0005515,GO:0003677,GO:0005634,GO:0005737,GO:0048471,GO:0043231,GO:0000785,GO:0001741,GO:0033391,GO:0071547,GO:0043186,GO:0030849,GO:0000122,GO:0030154,GO:0007275,GO:0043066,GO:0007283,GO:0006974,GO:0007140,GO:0009566,GO:0031047,GO:0000902,GO:0007129,GO:0046620,GO:0034587,GO:0043046,GO:0010629,GO:0008630","protein binding,DNA binding,nucleus,cytoplasm,perinuclear region of cytoplasm,intracellular membrane-bounded organelle,chromatin,XY body,chromatoid body,piP-body,P granule,autosome,negative regulation of transcription from RNA polymerase II promoter,cell differentiation,multicellular organismal development,negative regulation of apoptotic process,spermatogenesis,cellular response to DNA damage stimulus,male meiosis,fertilization,gene silencing by RNA,cell morphogenesis,synapsis,regulation of organ growth,piRNA metabolic process,DNA methylation involved in gamete generation,negative regulation of gene expression,intrinsic apoptotic signaling pathway in response to DNA damage","."]
["RRP1B","ribosomal RNA processing 1 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:23818]","ENSG00000160208","ENSP00000339145",1,"Nop52[1]","family-174","RRP1,RRP1B","RRP1","RRP1B[44,27]","rRNA","rRNA"," 20926688, Essential evolutionarily conserved nucleolar protein; necessary for biogenesis of 60S ribosomal subunits and for processing of pre-rRNAs to mature rRNA; associated with several distinct 66S pre-ribosomal particles","candidate mRNA binder","RNArelated",1,1,1,".","GO:0030688,GO:0006364","preribosome, small subunit precursor,rRNA processing","GO:0005515,GO:0005634,GO:0005829,GO:0005730,GO:0000792,GO:0030688,GO:0000791,GO:0006364,GO:0010923","protein binding,nucleus,cytosol,nucleolus,heterochromatin,preribosome, small subunit precursor,euchromatin,rRNA processing,negative regulation of phosphatase activity","."]
["RRP1","ribosomal RNA processing 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:18785]","ENSG00000160214","ENSP00000417464",1,"Nop52[1]","family-174","RRP1,RRP1B","RRP1","RRP1B[44,27]","rRNA","putative rRNA","The protein encoded by this gene is the putative homolog of the yeast ribosomal RNA processing protein RRP1. The encoded protein is involved in the late stages of nucleologenesis at the end of mitosis, and may be required for the generation of 28S rRNA. [provided by RefSeq, Jul 2008]","candidate mRNA binder","RNArelated",1,1,1,".","GO:0030688,GO:0006364","preribosome, small subunit precursor,rRNA processing","GO:0030688,GO:0006364,GO:0005634,GO:0005730","preribosome, small subunit precursor,rRNA processing,nucleus,nucleolus","."]
["ZC3HAV1","zinc finger CCCH-type, antiviral 1 [Source:HGNC Symbol;Acc:23721]","ENSG00000105939","ENSP00000418385",1,"PARP[1]","family-175","PARP11,PARP12,TIPARP,ZC3HAV1,PARP10,PARP14,PARP15","PARP11","PARP12[35,17],TIPARP[29,15],ZC3HAV1[27,10],PARP10[22,7],PARP14[28,5],PARP15[26,13]","ncRNA","viral RNA",20451500,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0071360,GO:0061014","RNA binding,cellular response to exogenous dsRNA,positive regulation of mRNA catabolic process","GO:0003723,GO:0005515,GO:0046872,GO:0003950,GO:0005634,GO:0005886,GO:0005737,GO:0005794,GO:0045087,GO:0043123,GO:0009615,GO:0032728,GO:0045071,GO:0071360,GO:0051607,GO:0032727,GO:0032481,GO:1900246,GO:0061014","RNA binding,protein binding,metal ion binding,NAD+ ADP-ribosyltransferase activity,nucleus,plasma membrane,cytoplasm,Golgi apparatus,innate immune response,positive regulation of I-kappaB kinase/NF-kappaB signaling,response to virus,positive regulation of interferon-beta production,negative regulation of viral genome replication,cellular response to exogenous dsRNA,defense response to virus,positive regulation of interferon-alpha production,positive regulation of type I interferon production,positive regulation of RIG-I signaling pathway,positive regulation of mRNA catabolic process","."]
["PARP12","poly (ADP-ribose) polymerase family, member 12 [Source:HGNC Symbol;Acc:21919]","ENSG00000059378","ENSP00000263549",2,"PARP[1],zf-CCCH[1]","family-175","PARP11,PARP12,TIPARP,ZC3HAV1,PARP10,PARP14,PARP15","PARP11","PARP12[35,17],TIPARP[29,15],ZC3HAV1[27,10],PARP10[22,7],PARP14[28,5],PARP15[26,13]","unknown","unknown","by homology",".","novel",".",1,".",1,".",".","GO:0003950,GO:0046872,GO:0005634","NAD+ ADP-ribosyltransferase activity,metal ion binding,nucleus","."]
["TIPARP","TCDD-inducible poly(ADP-ribose) polymerase [Source:HGNC Symbol;Acc:23696]","ENSG00000163659","ENSP00000420141",2,"PARP[1],WWE[1]","family-175","PARP11,PARP12,TIPARP,ZC3HAV1,PARP10,PARP14,PARP15","PARP11","PARP12[35,17],TIPARP[29,15],ZC3HAV1[27,10],PARP10[22,7],PARP14[28,5],PARP15[26,13]","unknown","unknown","This gene encodes a member of the poly(ADP-ribose) polymerase superfamily. Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]",".",".",".",".",".",1,".",".","GO:0046872,GO:0003950,GO:0008585,GO:0009791,GO:0006807,GO:0048745,GO:0048008,GO:0030097,GO:0006471,GO:0001822,GO:0048705,GO:0060021,GO:0001570,GO:0008209,GO:0008210,GO:0044236,GO:0060325","metal ion binding,NAD+ ADP-ribosyltransferase activity,female gonad development,post-embryonic development,nitrogen compound metabolic process,smooth muscle tissue development,platelet-derived growth factor receptor signaling pathway,hemopoiesis,protein ADP-ribosylation,kidney development,skeletal system morphogenesis,palate development,vasculogenesis,androgen metabolic process,estrogen metabolic process,multicellular organismal metabolic process,face morphogenesis","."]
["MRPS17","mitochondrial ribosomal protein S17 [Source:HGNC Symbol;Acc:14047]","ENSG00000239789","ENSP00000401349",1,"Ribosomal_S17[1]","family-176","MRPS17",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0019843,GO:0005763","structural constituent of ribosome,ribosome,translation,rRNA binding,mitochondrial small ribosomal subunit","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0019843,GO:0005763,GO:0003676,GO:0006355","structural constituent of ribosome,intracellular,ribosome,translation,rRNA binding,mitochondrial small ribosomal subunit,nucleic acid binding,regulation of transcription, DNA-dependent","."]
["U2AF2","U2 small nuclear RNA auxiliary factor 2 [Source:HGNC Symbol;Acc:23156]","ENSG00000063244","ENSP00000307863",4,"RRM_1[2],Transformer[1],RRM_6[1]","family-177","U2AF2,UHMK1","U2AF2","UHMK1[20,22]","mRNA","mRNA","binds polypyrimidine tracts in introns","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0005681,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0048025","RNA binding,mRNA processing,spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0005515,GO:0019899,GO:0070742,GO:0005654,GO:0005681,GO:0008380,GO:0006366,GO:0010467,GO:0000398,GO:0006406,GO:0031124,GO:0048025,GO:0006369","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,protein binding,enzyme binding,C2H2 zinc finger domain binding,nucleoplasm,spliceosomal complex,RNA splicing,transcription from RNA polymerase II promoter,gene expression,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,termination of RNA polymerase II transcription","."]
["UHMK1","U2AF homology motif (UHM) kinase 1 [Source:HGNC Symbol;Acc:19683]","ENSG00000152332","ENSP00000420270",2,"RRM_5[1],Pkinase[1]","family-177","U2AF2,UHMK1","U2AF2","UHMK1[20,22]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0043021,GO:0071598,GO:0045948","RNA binding,ribonucleoprotein complex binding,neuronal ribonucleoprotein granule,positive regulation of translational initiation","GO:0003723,GO:0005515,GO:0005524,GO:0004674,GO:0016740,GO:0004672,GO:0019899,GO:0004713,GO:0043021,GO:0016772,GO:0005634,GO:0030424,GO:0032839,GO:0071598,GO:0006468,GO:0007050,GO:0018105,GO:0046777,GO:0031175,GO:0046825,GO:0045948,GO:0003676,GO:0005737","RNA binding,protein binding,ATP binding,protein serine/threonine kinase activity,transferase activity,protein kinase activity,enzyme binding,protein tyrosine kinase activity,ribonucleoprotein complex binding,transferase activity, transferring phosphorus-containing groups,nucleus,axon,dendrite cytoplasm,neuronal ribonucleoprotein granule,protein phosphorylation,cell cycle arrest,peptidyl-serine phosphorylation,protein autophosphorylation,neuron projection development,regulation of protein export from nucleus,positive regulation of translational initiation,nucleic acid binding,cytoplasm","."]
["NUP153","nucleoporin 153kDa [Source:HGNC Symbol;Acc:8062]","ENSG00000124789","ENSP00000262077",6,"Nup153[1],zf-RanBP[4],Nup_retrotrp_bd[1]","family-178","NUP153",".",".","diverse","diverse",11567018,".",".",".",".",".",".","GO:0051028,GO:0046832","mRNA transport,negative regulation of RNA export from nucleus","GO:0008270,GO:0005737,GO:0005730,GO:0031965,GO:0005515,GO:0005215,GO:0003677,GO:0042802,GO:0017056,GO:0005487,GO:0043495,GO:0005654,GO:0005643,GO:0034399,GO:0042405,GO:0044615,GO:0055085,GO:0044281,GO:0015031,GO:0000278,GO:0016032,GO:0005975,GO:0051028,GO:0019221,GO:0010827,GO:0015758,GO:0006913,GO:0019048,GO:0046718,GO:0075732,GO:0007077,GO:0008645,GO:0046832,GO:0051292","zinc ion binding,cytoplasm,nucleolus,nuclear membrane,protein binding,transporter activity,DNA binding,identical protein binding,structural constituent of nuclear pore,nucleocytoplasmic transporter activity,protein anchor,nucleoplasm,nuclear pore,nuclear periphery,nuclear inclusion body,nuclear pore nuclear basket,transmembrane transport,small molecule metabolic process,protein transport,mitotic cell cycle,viral process,carbohydrate metabolic process,mRNA transport,cytokine-mediated signaling pathway,regulation of glucose transport,glucose transport,nucleocytoplasmic transport,modulation by virus of host morphology or physiology,viral entry into host cell,viral penetration into host nucleus,mitotic nuclear envelope disassembly,hexose transport,negative regulation of RNA export from nucleus,nuclear pore complex assembly","."]
["CSDE1","cold shock domain containing E1, RNA-binding [Source:HGNC Symbol;Acc:29905]","ENSG00000009307","ENSP00000407724",6,"SUZ-C[1],CSD[5]","family-179","CSDE1",".",".","mRNA","mRNA",17947529,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0070937,GO:0070966","RNA binding,CRD-mediated mRNA stability complex,nuclear-transcribed mRNA catabolic process, no-go decay","GO:0005743,GO:0003676,GO:0003677,GO:0006355,GO:0003723,GO:0070937,GO:0008584,GO:0070966","mitochondrial inner membrane,nucleic acid binding,DNA binding,regulation of transcription, DNA-dependent,RNA binding,CRD-mediated mRNA stability complex,male gonad development,nuclear-transcribed mRNA catabolic process, no-go decay","."]
["POLR2L","polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa [Source:HGNC Symbol;Acc:9199]","ENSG00000177700","ENSP00000324124",1,"RNA_pol_N[1]","family-18","POLR2L",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0008270,GO:0003677,GO:0001055,GO:0003899,GO:0001056,GO:0001054,GO:0005634,GO:0005829,GO:0005654,GO:0005665,GO:0005736,GO:0005666,GO:0006351,GO:0045087,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0006383,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0032481,GO:0006283,GO:0050434,GO:0006385,GO:0006386,GO:0006356","zinc ion binding,DNA binding,RNA polymerase II activity,DNA-directed RNA polymerase activity,RNA polymerase III activity,RNA polymerase I activity,nucleus,cytosol,nucleoplasm,DNA-directed RNA polymerase II, core complex,DNA-directed RNA polymerase I complex,DNA-directed RNA polymerase III complex,transcription, DNA-templated,innate immune response,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,transcription from RNA polymerase III promoter,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,positive regulation of type I interferon production,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription,transcription elongation from RNA polymerase III promoter,termination of RNA polymerase III transcription,regulation of transcription from RNA polymerase I promoter","."]
["NKRF","NFKB repressing factor [Source:HGNC Symbol;Acc:19374]","ENSG00000186416","ENSP00000442308",3,"DUF3469[1],dsrm[1],R3H[1]","family-180","NKRF",".",".","unknown","unknown","established RBP ","RNAbinding","RNAbinding",1,1,".",".",".",".","GO:0005515,GO:0003676,GO:0003677,GO:0005634,GO:0005730,GO:0006351,GO:0045892","protein binding,nucleic acid binding,DNA binding,nucleus,nucleolus,transcription, DNA-templated,negative regulation of transcription, DNA-dependent","."]
["MRPL48","mitochondrial ribosomal protein L48 [Source:HGNC Symbol;Acc:16653]","ENSG00000175581","ENSP00000399076",1,"Ribosomal_S10[1]","family-181","MRPL48",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005761","mitochondrial ribosome","GO:0005761,GO:0005515,GO:0005739","mitochondrial ribosome,protein binding,mitochondrion","."]
["XRCC6","X-ray repair complementing defective repair in Chinese hamster cells 6 [Source:HGNC Symbol;Acc:4055]","ENSG00000196419","ENSP00000403679",4,"SAP[1],Ku[1],Ku_C[1],Ku_N[1]","family-182","XRCC6",".",".","mRNA","putative mRNA",22190748,"helicase","RNArelated",1,1,".",".",".",".","GO:0003676,GO:0003677,GO:0004003,GO:0003684,GO:0042162,GO:0005634,GO:0005737,GO:0043564,GO:0000723,GO:0006303,GO:0010212,GO:0050769,GO:0033151,GO:0005515,GO:0005524,GO:0003690,GO:0008022,GO:0044212,GO:0051575,GO:0003691,GO:0005667,GO:0016020,GO:0005829,GO:0005654,GO:0000783,GO:0070419,GO:0006351,GO:0045944,GO:0045087,GO:0045893,GO:0045892,GO:0006281,GO:0016032,GO:0006302,GO:0032481,GO:0075713,GO:0006266,GO:0043234,GO:0005730,GO:0006974,GO:0071475,GO:0071481,GO:0007420","nucleic acid binding,DNA binding,ATP-dependent DNA helicase activity,damaged DNA binding,telomeric DNA binding,nucleus,cytoplasm,Ku70:Ku80 complex,telomere maintenance,double-strand break repair via nonhomologous end joining,response to ionizing radiation,positive regulation of neurogenesis,V(D)J recombination,protein binding,ATP binding,double-stranded DNA binding,protein C-terminus binding,transcription regulatory region DNA binding,5'-deoxyribose-5-phosphate lyase activity,double-stranded telomeric DNA binding,transcription factor complex,membrane,cytosol,nucleoplasm,nuclear telomere cap complex,nonhomologous end joining complex,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,innate immune response,positive regulation of transcription, DNA-dependent,negative regulation of transcription, DNA-dependent,DNA repair,viral process,double-strand break repair,positive regulation of type I interferon production,establishment of integrated proviral latency,DNA ligation,protein complex,nucleolus,cellular response to DNA damage stimulus,cellular hyperosmotic salinity response,cellular response to X-ray,brain development","."]
["SUPT5H","suppressor of Ty 5 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:11469]","ENSG00000196235","ENSP00000469090",6,"KOW[3],CTD[1],Spt5-NGN[1],Spt5_N[1]","family-183","SUPT5H",".",".","mRNA","mRNA",23041311,"RNAbinding","RNArelated",1,1,".",".","GO:0006370","7-methylguanosine mRNA capping","GO:0005515,GO:0046982,GO:0019899,GO:0003682,GO:0005634,GO:0005654,GO:0032044,GO:0000122,GO:0045944,GO:0006366,GO:0006355,GO:0016032,GO:0010467,GO:0007049,GO:0006357,GO:0006368,GO:0006370,GO:0006338,GO:0010033,GO:0016239,GO:0032784,GO:0032786,GO:0006354,GO:0032785,GO:0039692,GO:0050434","protein binding,protein heterodimerization activity,enzyme binding,chromatin binding,nucleus,nucleoplasm,DSIF complex,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,viral process,gene expression,cell cycle,regulation of transcription from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,chromatin remodeling,response to organic substance,positive regulation of macroautophagy,regulation of DNA-dependent transcription, elongation,positive regulation of DNA-dependent transcription, elongation,DNA-dependent transcription, elongation,negative regulation of DNA-dependent transcription, elongation,single stranded viral RNA replication via double stranded DNA intermediate,positive regulation of viral transcription","."]
["TSR3","TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:14175]","ENSG00000007520","ENSP00000007390",2,"DUF367[1],RLI[1]","family-184","TSR3",".",".","rRNA","rRNA","by homology",".",".",".",".",".",".","GO:0006364","rRNA processing","GO:0006364","rRNA processing","."]
["XRN2","5'-3' exoribonuclease 2 [Source:HGNC Symbol;Acc:12836]","ENSG00000088930","ENSP00000413548",1,"XRN_N[1]","family-185","XRN2",".",".","diverse","diverse","established RBP ","nuclease","RNArelated",1,1,1,".","GO:0004527,GO:0004534,GO:0008409,GO:0016070,GO:0006397,GO:0006396,GO:0006401","exonuclease activity,5'-3' exoribonuclease activity,5'-3' exonuclease activity,RNA metabolic process,mRNA processing,RNA processing,RNA catabolic process","GO:0008270,GO:0003676,GO:0004527,GO:0004518,GO:0004534,GO:0008409,GO:0005634,GO:0005622,GO:0005730,GO:0016235,GO:0007283,GO:0006355,GO:0016070,GO:0006397,GO:0006396,GO:0016049,GO:0006139,GO:0006401,GO:0006353,GO:0000738,GO:0005515","zinc ion binding,nucleic acid binding,exonuclease activity,nuclease activity,5'-3' exoribonuclease activity,5'-3' exonuclease activity,nucleus,intracellular,nucleolus,aggresome,spermatogenesis,regulation of transcription, DNA-dependent,RNA metabolic process,mRNA processing,RNA processing,cell growth,nucleobase-containing compound metabolic process,RNA catabolic process,DNA-dependent transcription, termination,DNA catabolic process, exonucleolytic,protein binding","."]
["RSRC1","arginine/serine-rich coiled-coil 1 [Source:HGNC Symbol;Acc:24152]","ENSG00000174891","ENSP00000295930",1,"THRAP3_BCLAF1[1]","family-186","RSRC1",".",".","mRNA","mRNA","This gene encodes a member of the serine and arginine rich-related protein family. The encoded protein is involved in both constitutive and alternative mRNA splicing. This gene may be associated with schizophrenia. A pseudogene of this gene is located on chromosome 9. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]",".",".",".",".",".",".","GO:0000380,GO:0008380,GO:0000398","alternative mRNA splicing, via spliceosome,RNA splicing,mRNA splicing, via spliceosome","GO:0005737,GO:0016607,GO:0046677,GO:0006468,GO:0006913,GO:0000380,GO:0005515,GO:0005634,GO:0008380,GO:0000398","cytoplasm,nuclear speck,response to antibiotic,protein phosphorylation,nucleocytoplasmic transport,alternative mRNA splicing, via spliceosome,protein binding,nucleus,RNA splicing,mRNA splicing, via spliceosome","."]
["TDRD5","tudor domain containing 5 [Source:HGNC Symbol;Acc:20614]","ENSG00000162782","ENSP00000406052",4,"TUDOR[1],OST-HTH[3]","family-187","TDRD5",".",".","ncRNA","piRNA related",21383078,".",".",".",".",".",".","GO:0071546","pi-body","GO:0033391,GO:0071546,GO:0043046,GO:0007286,GO:0030719","chromatoid body,pi-body,DNA methylation involved in gamete generation,spermatid development,P granule organization","."]
["POLR2J","polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa [Source:HGNC Symbol;Acc:9197]","ENSG00000005075","ENSP00000292614",1,"RNA_pol_L_2[1]","family-188","POLR2J,POLR2J2,POLR2J3","POLR2J","POLR2J2[89,90],POLR2J3[90,91]","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0046983,GO:0003899,GO:0006351,GO:0005515,GO:0001055,GO:0030275,GO:0005634,GO:0005665,GO:0005654,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","DNA binding,protein dimerization activity,DNA-directed RNA polymerase activity,transcription, DNA-templated,protein binding,RNA polymerase II activity,LRR domain binding,nucleus,DNA-directed RNA polymerase II, core complex,nucleoplasm,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["POLR2J2","DNA-directed RNA polymerase II subunit RPB11-b1 [Source:RefSeq peptide;Acc:NP_116581]","ENSG00000228049","ENSP00000466522",1,"RNA_pol_L_2[1]","family-188","POLR2J,POLR2J2,POLR2J3","POLR2J","POLR2J2[89,90],POLR2J3[90,91]","mRNA","mRNA","Pol II complex",".",".",".",".",".",".",".",".","GO:0003677,GO:0046983,GO:0003899,GO:0006351,GO:0001055,GO:0005665,GO:0006366","DNA binding,protein dimerization activity,DNA-directed RNA polymerase activity,transcription, DNA-templated,RNA polymerase II activity,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter","."]
["POLR2J3","polymerase (RNA) II (DNA directed) polypeptide J3 [Source:HGNC Symbol;Acc:33853]","ENSG00000168255","ENSP00000368662",".",".","family-188","POLR2J,POLR2J2,POLR2J3","POLR2J","POLR2J2[89,90],POLR2J3[90,91]","mRNA","mRNA","Pol II complex",".",".",".",".",".",".",".",".","GO:0016021,GO:0046983,GO:0006351,GO:0003677,GO:0003899,GO:0005634","integral to membrane,protein dimerization activity,transcription, DNA-templated,DNA binding,DNA-directed RNA polymerase activity,nucleus","."]
["SAFB2","scaffold attachment factor B2 [Source:HGNC Symbol;Acc:21605]","ENSG00000130254","ENSP00000252542",2,"SAP[1],RRM_1[1]","family-189","SAFB,SAFB2,SLTM","SAFB","SAFB2[71,69],SLTM[32,28]","mRNA","mRNA",17200140,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0003676,GO:0000166,GO:0003723,GO:0005515,GO:0003677,GO:0042802,GO:0005634,GO:0005737,GO:0006351,GO:0006355","nucleic acid binding,nucleotide binding,RNA binding,protein binding,DNA binding,identical protein binding,nucleus,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["SAFB","scaffold attachment factor B [Source:HGNC Symbol;Acc:10520]","ENSG00000160633","ENSP00000292123",2,"SAP[1],RRM_6[1]","family-189","SAFB,SAFB2,SLTM","SAFB","SAFB2[71,69],SLTM[32,28]","mRNA","mRNA","17200140, 9671816","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0001047,GO:0003676,GO:0003682,GO:0005634,GO:0045944,GO:0040007,GO:0042445,GO:0030520,GO:0005515,GO:0003723,GO:0003690,GO:0006351,GO:0006325","nucleotide binding,core promoter binding,nucleic acid binding,chromatin binding,nucleus,positive regulation of transcription from RNA polymerase II promoter,growth,hormone metabolic process,intracellular estrogen receptor signaling pathway,protein binding,RNA binding,double-stranded DNA binding,transcription, DNA-templated,chromatin organization","."]
["SLTM","SAFB-like, transcription modulator [Source:HGNC Symbol;Acc:20709]","ENSG00000137776","ENSP00000369887",2,"SAP[1],RRM_1[1]","family-189","SAFB,SAFB2,SLTM","SAFB","SAFB2[71,69],SLTM[32,28]","mRNA","putative mRNA","22658674, 22681889, 17630952","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723","RNA binding","GO:0003676,GO:0005634,GO:0000166,GO:0003723,GO:0006351,GO:0006915,GO:0006355","nucleic acid binding,nucleus,nucleotide binding,RNA binding,transcription, DNA-templated,apoptotic process,regulation of transcription, DNA-dependent","."]
["BRIX1","BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24170]","ENSG00000113460","ENSP00000338862",1,"Brix[1]","family-19","BRIX1",".",".","rRNA","rRNA","established RBP ","candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005634,GO:0005730,GO:0042254","nucleus,nucleolus,ribosome biogenesis","."]
["POLR2I","polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa [Source:HGNC Symbol;Acc:9196]","ENSG00000105258","ENSP00000221859",2,"RNA_POL_M_15KD[1],TFIIS_C[1]","family-190","POLR2I",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003899,GO:0006351,GO:0008270,GO:0003676,GO:0005634,GO:0005654,GO:0005665,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","DNA binding,DNA-directed RNA polymerase activity,transcription, DNA-templated,zinc ion binding,nucleic acid binding,nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["PWP2","PWP2 periodic tryptophan protein homolog (yeast) [Source:HGNC Symbol;Acc:9711]","ENSG00000241945","ENSP00000291576",4,"Utp12[1],WD40[3]","family-191","PWP2",".",".","snoRNA","snoRNA","UTP1 yeast homolog","RNAbinding","novel",1,1,1,".",".",".","GO:0005515,GO:0004871,GO:0005737,GO:0005730,GO:0007165","protein binding,signal transducer activity,cytoplasm,nucleolus,signal transduction","."]
["ELAC2","elaC homolog 2 (E. coli) [Source:HGNC Symbol;Acc:14198]","ENSG00000006744","ENSP00000337445",2,"Lactamase_B_2[1],Lactamase_B_4[1]","family-192","ELAC2",".",".","tRNA","tRNA","established RBP ","nuclease","RNArelated",1,1,1,".",".",".","GO:0016787,GO:0005739,GO:0046872,GO:0004519,GO:0005634,GO:0072684","hydrolase activity,mitochondrion,metal ion binding,endonuclease activity,nucleus,mitochondrial tRNA 3'-trailer cleavage, endonucleolytic"," PROSTATE CANCER"]
["ZCCHC14","zinc finger, CCHC domain containing 14 [Source:HGNC Symbol;Acc:24134]","ENSG00000140948","ENSP00000268616",2,"zf-CCHC[1],SAM_1[1]","family-193","ZCCHC14,ZCCHC2","ZCCHC14","ZCCHC2[25,20]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0008270,GO:0003676,GO:0035091,GO:0007154","zinc ion binding,nucleic acid binding,phosphatidylinositol binding,cell communication","."]
["ZCCHC2","zinc finger, CCHC domain containing 2 [Source:HGNC Symbol;Acc:22916]","ENSG00000141664","ENSP00000464791",1,"zf-CCHC[1]","family-193","ZCCHC14,ZCCHC2","ZCCHC14","ZCCHC2[25,20]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0008270,GO:0003676,GO:0035091,GO:0007154,GO:0005737","zinc ion binding,nucleic acid binding,phosphatidylinositol binding,cell communication,cytoplasm","."]
["LARS","leucyl-tRNA synthetase [Source:HGNC Symbol;Acc:6512]","ENSG00000133706","ENSP00000426005",3,"Anticodon_1[1],tRNA-synt_1[2]","family-194","LARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0002161,GO:0004812,GO:0004823,GO:0006418,GO:0006429","aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,leucine-tRNA ligase activity,tRNA aminoacylation for protein translation,leucyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0002161,GO:0004812,GO:0004823,GO:0005737,GO:0006418,GO:0006429,GO:0005515,GO:0005829,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,leucine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,leucyl-tRNA aminoacylation,protein binding,cytosol,gene expression","."]
["MRPL28","mitochondrial ribosomal protein L28 [Source:HGNC Symbol;Acc:14484]","ENSG00000086504","ENSP00000395305",1,"Ribosomal_L28[1]","family-195","MRPL28",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrial ribosome,translation","GO:0003735,GO:0005739,GO:0005515,GO:0005737,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrion,protein binding,cytoplasm,mitochondrial ribosome,translation","."]
["CNOT1","CCR4-NOT transcription complex, subunit 1 [Source:HGNC Symbol;Acc:7877]","ENSG00000125107","ENSP00000455635",2,"DUF3819[1],Not1[1]","family-196","CNOT1",".",".","mRNA","mRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0004535,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047,GO:0060213,GO:1900153","poly(A)-specific ribonuclease activity,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","GO:0005488,GO:0005515,GO:0042974,GO:0030331,GO:0004535,GO:0005634,GO:0005829,GO:0000932,GO:0005778,GO:0030014,GO:0000122,GO:0006351,GO:0007275,GO:0048387,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047,GO:0033147,GO:0060213,GO:1900153,GO:2000036","binding,protein binding,retinoic acid receptor binding,estrogen receptor binding,poly(A)-specific ribonuclease activity,nucleus,cytosol,cytoplasmic mRNA processing body,peroxisomal membrane,CCR4-NOT complex,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,multicellular organismal development,negative regulation of retinoic acid receptor signaling pathway,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA,negative regulation of intracellular estrogen receptor signaling pathway,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of stem cell maintenance","."]
["DDX18","DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Source:HGNC Symbol;Acc:2741]","ENSG00000088205","ENSP00000263239",3,"DUF4217[1],Helicase_C[1],DEAD[1]","family-197","DDX18",".",".","rRNA","putative rRNA","yeast homolog HAS1; ATP-dependent RNA helicase; involved in the biogenesis of 40S and 60S ribosome subunits; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0004004","RNA binding,ATP-dependent RNA helicase activity","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003723,GO:0005515,GO:0004004,GO:0005730","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA binding,protein binding,ATP-dependent RNA helicase activity,nucleolus","."]
["TSEN15","tRNA splicing endonuclease 15 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:16791]","ENSG00000198860","ENSP00000402002",1,"Sen15[1]","family-198","TSEN15",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000213,GO:0006397,GO:0006388","tRNA-intron endonuclease activity,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation","GO:0000213,GO:0005730,GO:0006397,GO:0006388","tRNA-intron endonuclease activity,nucleolus,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation","."]
["USP10","ubiquitin specific peptidase 10 [Source:HGNC Symbol;Acc:12608]","ENSG00000103194","ENSP00000219473",2,"PAM2[1],UCH[1]","family-199","USP10",".",".","mRNA","putative mRNA","22681889, 22658674, 23912277, 15003521","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0006511,GO:0004221,GO:0005515,GO:0004197,GO:0002039,GO:0044325,GO:0004843,GO:0005634,GO:0005737,GO:0005769,GO:0045111,GO:0006914,GO:0006281,GO:0010506,GO:0030330,GO:0016579","ubiquitin-dependent protein catabolic process,ubiquitin thiolesterase activity,protein binding,cysteine-type endopeptidase activity,p53 binding,ion channel binding,ubiquitin-specific protease activity,nucleus,cytoplasm,early endosome,intermediate filament cytoskeleton,autophagy,DNA repair,regulation of autophagy,DNA damage response, signal transduction by p53 class mediator,protein deubiquitination","."]
["SMNDC1","survival motor neuron domain containing 1 [Source:HGNC Symbol;Acc:16900]","ENSG00000119953","ENSP00000358605",1,"SMN[1]","family-2","SMNDC1",".",".","mRNA","mRNA","This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008]",".","RNAbinding",".",1,1,".","GO:0003723,GO:0005681,GO:0006397,GO:0008380,GO:0000375","RNA binding,spliceosomal complex,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0015030,GO:0006915,GO:0006397,GO:0008380,GO:0000375","RNA binding,protein binding,nucleus,cytoplasm,spliceosomal complex,nuclear speck,Cajal body,apoptotic process,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions","."]
["THUMPD2","THUMP domain containing 2 [Source:HGNC Symbol;Acc:14890]","ENSG00000138050","ENSP00000423933",2,"THUMP[1],UPF0020[1]","family-20","THUMPD2,THUMPD3","THUMPD2","THUMPD3[21,21]","tRNA","putative tRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0008168,GO:0008152","RNA binding,methyltransferase activity,metabolic process","."]
["THUMPD3","THUMP domain containing 3 [Source:HGNC Symbol;Acc:24493]","ENSG00000134077","ENSP00000339532",2,"THUMP[1],UPF0020[1]","family-20","THUMPD2,THUMPD3","THUMPD2","THUMPD3[21,21]","tRNA","putative tRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0008168","RNA binding,methyltransferase activity","."]
["SND1","staphylococcal nuclease and tudor domain containing 1 [Source:HGNC Symbol;Acc:30646]","ENSG00000197157","ENSP00000346762",6,"SNase[5],TUDOR[1]","family-200","SND1",".",".","mRNA","mRNA/miRNA",18603592,"RNAbinding","RNArelated",1,1,1,".","GO:0031047","gene silencing by RNA","GO:0003676,GO:0016788,GO:0005515,GO:0004518,GO:0003712,GO:0005634,GO:0005737,GO:0005739,GO:0042470,GO:0016442,GO:0006351,GO:0006355,GO:0031047,GO:0019048","nucleic acid binding,hydrolase activity, acting on ester bonds,protein binding,nuclease activity,transcription cofactor activity,nucleus,cytoplasm,mitochondrion,melanosome,RISC complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,gene silencing by RNA,modulation by virus of host morphology or physiology","."]
["LSM4","LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:17259]","ENSG00000130520","ENSP00000469468",1,"LSM[1]","family-201","LSM4",".",".","snRNA","snRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0005681,GO:0030532,GO:0005688,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0043928","RNA binding,spliceosomal complex,small nuclear ribonucleoprotein complex,U6 snRNP,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0005829,GO:0005681,GO:0030532,GO:0005688,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0043928","RNA binding,protein binding,cytosol,spliceosomal complex,small nuclear ribonucleoprotein complex,U6 snRNP,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["EIF3M","eukaryotic translation initiation factor 3, subunit M [Source:HGNC Symbol;Acc:24460]","ENSG00000149100","ENSP00000436049",1,"PCI[1]","family-202","EIF3M",".",".","mRNA","putative mRNA","This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]",".",".",".",".",".",".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0005515,GO:0005488,GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413","protein binding,binding,translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","."]
["MRPL34","mitochondrial ribosomal protein L34 [Source:HGNC Symbol;Acc:14488]","ENSG00000130312","ENSP00000472266",1,"Ribosomal_L34[1]","family-203","MRPL34",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0005761,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial ribosome,translation","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrion,intracellular,ribosome,mitochondrial ribosome,translation","."]
["SRP72","signal recognition particle 72kDa [Source:HGNC Symbol;Acc:11303]","ENSG00000174780","ENSP00000342181",4,"SRP72[1],TPR_12[2],Apc3[1]","family-204","SRP72",".",".","ncRNA","7SL","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0008312,GO:0006412","7S RNA binding,translation","GO:0005515,GO:0006614,GO:0008312,GO:0005047,GO:0005886,GO:0005737,GO:0005829,GO:0005783,GO:0005730,GO:0048500,GO:0005786,GO:0006412,GO:0042493,GO:0010467,GO:0044267","protein binding,SRP-dependent cotranslational protein targeting to membrane,7S RNA binding,signal recognition particle binding,plasma membrane,cytoplasm,cytosol,endoplasmic reticulum,nucleolus,signal recognition particle,signal recognition particle, endoplasmic reticulum targeting,translation,response to drug,gene expression,cellular protein metabolic process"," BONE MARROW FAILURE, FAMILIAL; BMFF"]
["SUGP1","SURP and G patch domain containing 1 [Source:HGNC Symbol;Acc:18643]","ENSG00000105705","ENSP00000247001",3,"G-patch[1],Surp[2]","family-205","SUGP1,SUGP2","SUGP1","SUGP2[22,13]","mRNA","mRNA","SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0005681,GO:0008380,GO:0000398,GO:0006396","RNA binding,spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005681,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0003676","RNA binding,protein binding,nucleus,nucleoplasm,spliceosomal complex,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,nucleic acid binding","."]
["SUGP2","SURP and G patch domain containing 2 [Source:HGNC Symbol;Acc:18641]","ENSG00000064607","ENSP00000409603",3,"G-patch[1],Surp[2]","family-205","SUGP1,SUGP2","SUGP1","SUGP2[22,13]","mRNA","putative mRNA","This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0006396,GO:0006397,GO:0008380","RNA binding,RNA processing,mRNA processing,RNA splicing","GO:0003723,GO:0003676,GO:0006396,GO:0005634,GO:0006397,GO:0008380","RNA binding,nucleic acid binding,RNA processing,nucleus,mRNA processing,RNA splicing","."]
["RPS3","ribosomal protein S3 [Source:HGNC Symbol;Acc:10420]","ENSG00000149273","ENSP00000433421",2,"KH_2[1],Ribosomal_S3_C[1]","family-206","RPS3",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,1,"GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0003729,GO:0022627,GO:0030529,GO:0015935,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,translation,mRNA binding,cytosolic small ribosomal subunit,ribonucleoprotein complex,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0005515,GO:0004519,GO:0019899,GO:0019901,GO:0003729,GO:0003684,GO:0051536,GO:0051018,GO:0051059,GO:0003906,GO:0005634,GO:0005737,GO:0005829,GO:0022627,GO:0030529,GO:0032587,GO:0015935,GO:0006974,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0032088,GO:0044267,GO:0006614,GO:0006919,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0045738,GO:1900119,GO:1902546","RNA binding,structural constituent of ribosome,ribosome,translation,protein binding,endonuclease activity,enzyme binding,protein kinase binding,mRNA binding,damaged DNA binding,iron-sulfur cluster binding,protein kinase A binding,NF-kappaB binding,DNA-(apurinic or apyrimidinic site) lyase activity,nucleus,cytoplasm,cytosol,cytosolic small ribosomal subunit,ribonucleoprotein complex,ruffle membrane,small ribosomal subunit,cellular response to DNA damage stimulus,viral process,gene expression,RNA metabolic process,mRNA metabolic process,negative regulation of NF-kappaB transcription factor activity,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,activation of cysteine-type endopeptidase activity involved in apoptotic process,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,negative regulation of DNA repair,positive regulation of execution phase of apoptosis,positive regulation of DNA N-glycosylase activity","."]
["RPS27A","ribosomal protein S27a [Source:HGNC Symbol;Acc:10417]","ENSG00000143947","ENSP00000272317",2,"Ribosomal_S27[1],ubiquitin[1]","family-207","RPS27A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0046872,GO:0003735,GO:0005886,GO:0005829,GO:0005622,GO:0022627,GO:0005840,GO:0010008,GO:0005654,GO:0015935,GO:0030666,GO:0000122,GO:0006351,GO:0045944,GO:0038095,GO:0045087,GO:0055085,GO:0006915,GO:0042981,GO:0043066,GO:0034220,GO:0043123,GO:0000209,GO:0006412,GO:0002474,GO:0000278,GO:0006281,GO:0016032,GO:0016197,GO:0019068,GO:0019082,GO:0002479,GO:0006977,GO:0010467,GO:0016070,GO:0016071,GO:0031145,GO:0042590,GO:0051437,GO:0051439,GO:0008585,GO:0000187,GO:0043065,GO:0032480,GO:0006367,GO:0007219,GO:0007254,GO:0019221,GO:0007179,GO:0030512,GO:0007141,GO:0071456,GO:0002224,GO:0072520,GO:0008543,GO:0051092,GO:0050852,GO:0044267,GO:0007173,GO:0032481,GO:0007249,GO:0000082,GO:0097190,GO:0002755,GO:0002756,GO:0034138,GO:0006614,GO:0034166,GO:0007220,GO:0051403,GO:0007144,GO:0010992,GO:0021888,GO:0060613,GO:0097009,GO:0042059,GO:0006414,GO:0034142,GO:0034162,GO:0048011,GO:0019058,GO:0034134,GO:0035666,GO:0038123,GO:0038124,GO:0051436,GO:0006413,GO:0034146,GO:0035872,GO:0061418,GO:0070423,GO:0000184,GO:0006415,GO:0019083,GO:0032479","protein binding,metal ion binding,structural constituent of ribosome,plasma membrane,cytosol,intracellular,cytosolic small ribosomal subunit,ribosome,endosome membrane,nucleoplasm,small ribosomal subunit,endocytic vesicle membrane,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,Fc-epsilon receptor signaling pathway,innate immune response,transmembrane transport,apoptotic process,regulation of apoptotic process,negative regulation of apoptotic process,ion transmembrane transport,positive regulation of I-kappaB kinase/NF-kappaB signaling,protein polyubiquitination,translation,antigen processing and presentation of peptide antigen via MHC class I,mitotic cell cycle,DNA repair,viral process,endosomal transport,virion assembly,viral protein processing,antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,gene expression,RNA metabolic process,mRNA metabolic process,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,antigen processing and presentation of exogenous peptide antigen via MHC class I,positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,female gonad development,activation of MAPK activity,positive regulation of apoptotic process,negative regulation of type I interferon production,transcription initiation from RNA polymerase II promoter,Notch signaling pathway,JNK cascade,cytokine-mediated signaling pathway,transforming growth factor beta receptor signaling pathway,negative regulation of transforming growth factor beta receptor signaling pathway,male meiosis I,cellular response to hypoxia,toll-like receptor signaling pathway,seminiferous tubule development,fibroblast growth factor receptor signaling pathway,positive regulation of NF-kappaB transcription factor activity,T cell receptor signaling pathway,cellular protein metabolic process,epidermal growth factor receptor signaling pathway,positive regulation of type I interferon production,I-kappaB kinase/NF-kappaB signaling,G1/S transition of mitotic cell cycle,apoptotic signaling pathway,MyD88-dependent toll-like receptor signaling pathway,MyD88-independent toll-like receptor signaling pathway,toll-like receptor 3 signaling pathway,SRP-dependent cotranslational protein targeting to membrane,toll-like receptor 10 signaling pathway,Notch receptor processing,stress-activated MAPK cascade,female meiosis I,ubiquitin homeostasis,hypothalamus gonadotrophin-releasing hormone neuron development,fat pad development,energy homeostasis,negative regulation of epidermal growth factor receptor signaling pathway,translational elongation,toll-like receptor 4 signaling pathway,toll-like receptor 9 signaling pathway,neurotrophin TRK receptor signaling pathway,viral life cycle,toll-like receptor 2 signaling pathway,TRIF-dependent toll-like receptor signaling pathway,toll-like receptor TLR1:TLR2 signaling pathway,toll-like receptor TLR6:TLR2 signaling pathway,negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,translational initiation,toll-like receptor 5 signaling pathway,nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway,regulation of transcription from RNA polymerase II promoter in response to hypoxia,nucleotide-binding oligomerization domain containing signaling pathway,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,regulation of type I interferon production","."]
["CCAR2","KIAA1967 [Source:HGNC Symbol;Acc:23360]","ENSG00000158941","ENSP00000373930",2,"DBC1[1],S1-like[1]","family-208","CCAR1,CCAR2","CCAR1","CCAR2[27,34]","mRNA","mRNA","22658674, 22681889","RNAbinding","novel",1,1,1,".","GO:0005681,GO:0044609,GO:0006397,GO:0008380","spliceosomal complex,DBIRD complex,mRNA processing,RNA splicing","GO:0006915,GO:0004857,GO:0005515,GO:0019899,GO:0000993,GO:0005634,GO:0005737,GO:0005759,GO:0005681,GO:0000790,GO:0044609,GO:0006974,GO:0007049,GO:0006397,GO:0008380,GO:0043065,GO:0009411,GO:0043086,GO:0043653,GO:0032784,GO:1902230,GO:2000003","apoptotic process,enzyme inhibitor activity,protein binding,enzyme binding,RNA polymerase II core binding,nucleus,cytoplasm,mitochondrial matrix,spliceosomal complex,nuclear chromatin,DBIRD complex,cellular response to DNA damage stimulus,cell cycle,mRNA processing,RNA splicing,positive regulation of apoptotic process,response to UV,negative regulation of catalytic activity,mitochondrial fragmentation involved in apoptotic process,regulation of DNA-dependent transcription, elongation,negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage,positive regulation of DNA damage checkpoint","."]
["CCAR1","cell division cycle and apoptosis regulator 1 [Source:HGNC Symbol;Acc:24236]","ENSG00000060339","ENSP00000439252",4,"SAP[1],DBC1[1],MIP-T3[1],S1-like[1]","family-208","CCAR1,CCAR2","CCAR1","CCAR2[27,34]","mRNA","mRNA","24608801, 19073175","candidate mRNA binder","RNArelated",1,1,".",1,"GO:0008380,GO:0000398","RNA splicing,mRNA splicing, via spliceosome","GO:0005515,GO:0003676,GO:0030374,GO:0048471,GO:0005654,GO:0006351,GO:0006915,GO:0006355,GO:0010467,GO:0007049,GO:0008380,GO:0000398","protein binding,nucleic acid binding,ligand-dependent nuclear receptor transcription coactivator activity,perinuclear region of cytoplasm,nucleoplasm,transcription, DNA-templated,apoptotic process,regulation of transcription, DNA-dependent,gene expression,cell cycle,RNA splicing,mRNA splicing, via spliceosome","."]
["DDX49","DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Source:HGNC Symbol;Acc:18684]","ENSG00000105671","ENSP00000395377",2,"Helicase_C[1],DEAD[1]","family-209","DDX49",".",".","rRNA","rRNA","yeast homolog DBP8",".","RNAbinding",".",1,1,".","GO:0003723","RNA binding","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003723","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA binding","."]
["MRPL4","mitochondrial ribosomal protein L4 [Source:HGNC Symbol;Acc:14276]","ENSG00000105364","ENSP00000377334",1,"Ribosomal_L4[1]","family-21","MRPL4",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005840,GO:0006412","structural constituent of ribosome,mitochondrion,ribosome,translation","."]
["SFSWAP","splicing factor, suppressor of white-apricot homolog (Drosophila) [Source:HGNC Symbol;Acc:10790]","ENSG00000061936","ENSP00000437738",3,"Surp[2],DRY_EERY[1]","family-210","SFSWAP",".",".","mRNA","mRNA","This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]",".",".",".",".",".",1,"GO:0003723,GO:0006396,GO:0006397,GO:0006376,GO:0048025","RNA binding,RNA processing,mRNA processing,mRNA splice site selection,negative regulation of mRNA splicing, via spliceosome","GO:0003723,GO:0006396,GO:0005634,GO:0006351,GO:0006355,GO:0006397,GO:0006376,GO:0048025","RNA binding,RNA processing,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent,mRNA processing,mRNA splice site selection,negative regulation of mRNA splicing, via spliceosome","."]
["MRPS12","mitochondrial ribosomal protein S12 [Source:HGNC Symbol;Acc:10380]","ENSG00000128626","ENSP00000384952",1,"Ribosom_S12_S23[1]","family-211","MRPS12",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0015935,GO:0005761,GO:0006412","structural constituent of ribosome,ribosome,small ribosomal subunit,mitochondrial ribosome,translation","GO:0005515,GO:0003735,GO:0005622,GO:0005840,GO:0015935,GO:0005761,GO:0006412,GO:0005739","protein binding,structural constituent of ribosome,intracellular,ribosome,small ribosomal subunit,mitochondrial ribosome,translation,mitochondrion","."]
["EIF1","eukaryotic translation initiation factor 1 [Source:HGNC Symbol;Acc:3249]","ENSG00000173812","ENSP00000467918",1,"SUI1[1]","family-212","EIF1,EIF1B","EIF1","EIF1B[91,91]","mRNA","putative mRNA",20921384,"translationfactor",".",".",1,".",".","GO:0003743,GO:0006413,GO:0008135,GO:0006446","translation initiation factor activity,translational initiation,translation factor activity, nucleic acid binding,regulation of translational initiation","GO:0003743,GO:0006413,GO:0008135,GO:0005737,GO:0006950,GO:0006446,GO:0009048","translation initiation factor activity,translational initiation,translation factor activity, nucleic acid binding,cytoplasm,response to stress,regulation of translational initiation,dosage compensation by inactivation of X chromosome","."]
["EIF1B","eukaryotic translation initiation factor 1B [Source:HGNC Symbol;Acc:30792]","ENSG00000114784","ENSP00000232905",1,"SUI1[1]","family-212","EIF1,EIF1B","EIF1","EIF1B[91,91]","mRNA","putative mRNA","established RBP ","translationfactor",".",".",1,".",".","GO:0003743,GO:0006446,GO:0006413","translation initiation factor activity,regulation of translational initiation,translational initiation","GO:0003743,GO:0006446,GO:0006413","translation initiation factor activity,regulation of translational initiation,translational initiation","."]
["CLP1","cleavage and polyadenylation factor I subunit 1 [Source:HGNC Symbol;Acc:16999]","ENSG00000172409","ENSP00000434995",2,"MobB[1],Clp1[1]","family-213","CLP1",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0000214,GO:0005849,GO:0008380,GO:0000398,GO:0006388,GO:0031124,GO:0035087,GO:0030423","tRNA-intron endonuclease complex,mRNA cleavage factor complex,RNA splicing,mRNA splicing, via spliceosome,tRNA splicing, via endonucleolytic cleavage and ligation,mRNA 3'-end processing,siRNA loading onto RISC involved in RNA interference,targeting of mRNA for destruction involved in RNA interference","GO:0005524,GO:0051733,GO:0051736,GO:0046404,GO:0005654,GO:0000214,GO:0005849,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006388,GO:0031124,GO:0035087,GO:0006369,GO:0030423","ATP binding,polydeoxyribonucleotide kinase activity,ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity,ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity,nucleoplasm,tRNA-intron endonuclease complex,mRNA cleavage factor complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,tRNA splicing, via endonucleolytic cleavage and ligation,mRNA 3'-end processing,siRNA loading onto RISC involved in RNA interference,termination of RNA polymerase II transcription,targeting of mRNA for destruction involved in RNA interference","."]
["ZMAT5","zinc finger, matrin-type 5 [Source:HGNC Symbol;Acc:28046]","ENSG00000100319","ENSP00000344241",2,"zf-CCCH[1],zf-U1[1]","family-214","ZMAT5",".",".","snRNA","snRNA","SNRNP20, 19878916",".",".",".",".",".",1,"GO:0005689,GO:0006397,GO:0008380","U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0008270,GO:0046872,GO:0005634,GO:0005737,GO:0005689,GO:0006397,GO:0008380","zinc ion binding,metal ion binding,nucleus,cytoplasm,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["SF3B3","splicing factor 3b, subunit 3, 130kDa [Source:HGNC Symbol;Acc:10770]","ENSG00000189091","ENSP00000305790",2,"MMS1_N[1],CPSF_A[1]","family-215","DDB1,SF3B3","DDB1","SF3B3[24,22]","mRNA","mRNA","This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0000375","spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0005515,GO:0003676,GO:0005634,GO:0005654,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006461,GO:0000375","protein binding,nucleic acid binding,nucleus,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,protein complex assembly,RNA splicing, via transesterification reactions","."]
["PLD6","phospholipase D family, member 6 [Source:HGNC Symbol;Acc:30447]","ENSG00000179598","ENSP00000317177",1,"PLDc_2[1]","family-216","PLD6",".",".","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0034587","piRNA metabolic process","GO:0042803,GO:0046872,GO:0004519,GO:0003824,GO:0035755,GO:0005741,GO:0016021,GO:0043046,GO:0007286,GO:0007126,GO:0034587,GO:0030719,GO:0044281,GO:0016042,GO:0008152,GO:0008053,GO:0006644,GO:0046474,GO:0006655","protein homodimerization activity,metal ion binding,endonuclease activity,catalytic activity,cardiolipin hydrolase activity,mitochondrial outer membrane,integral to membrane,DNA methylation involved in gamete generation,spermatid development,meiosis,piRNA metabolic process,P granule organization,small molecule metabolic process,lipid catabolic process,metabolic process,mitochondrial fusion,phospholipid metabolic process,glycerophospholipid biosynthetic process,phosphatidylglycerol biosynthetic process","."]
["QTRTD1","queuine tRNA-ribosyltransferase domain containing 1 [Source:HGNC Symbol;Acc:25771]","ENSG00000151576","ENSP00000281273",1,"TGT[1]","family-217","QTRT1,QTRTD1","QTRT1","QTRTD1[22,21]","tRNA","tRNA","This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]",".",".",".",".",".",".","GO:0008479,GO:0006400","queuine tRNA-ribosyltransferase activity,tRNA modification","GO:0008479,GO:0008616,GO:0006400,GO:0008270,GO:0005737,GO:0005739","queuine tRNA-ribosyltransferase activity,queuosine biosynthetic process,tRNA modification,zinc ion binding,cytoplasm,mitochondrion","."]
["QTRT1","queuine tRNA-ribosyltransferase 1 [Source:HGNC Symbol;Acc:23797]","ENSG00000213339","ENSP00000465974",1,"TGT[1]","family-217","QTRT1,QTRTD1","QTRT1","QTRTD1[22,21]","tRNA","tRNA","This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]",".",".",".",".",".",".","GO:0008479,GO:0006400,GO:0005840,GO:0008033","queuine tRNA-ribosyltransferase activity,tRNA modification,ribosome,tRNA processing","GO:0008479,GO:0008616,GO:0006400,GO:0005515,GO:0046872,GO:0005737,GO:0005634,GO:0005739,GO:0005840,GO:0008033","queuine tRNA-ribosyltransferase activity,queuosine biosynthetic process,tRNA modification,protein binding,metal ion binding,cytoplasm,nucleus,mitochondrion,ribosome,tRNA processing","."]
["PIH1D1","PIH1 domain containing 1 [Source:HGNC Symbol;Acc:26075]","ENSG00000104872","ENSP00000469087",2,"PIH1[2]","family-218","PIH1D1",".",".","snoRNA","snoRNA",17636026,".",".",".",".",".",".","GO:0070761,GO:0000492","pre-snoRNP complex,box C/D snoRNP assembly","GO:0070761,GO:0000492","pre-snoRNP complex,box C/D snoRNP assembly","."]
["SWT1","SWT1 RNA endoribonuclease homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:16785]","ENSG00000116668","ENSP00000356471",1,"PIN_4[1]","family-219","SWT1",".",".","mRNA","putative mRNA","RNA endoribonuclease involved in perinuclear mRNP quality control; involved in perinuclear mRNP quality control via the turnover of aberrant, unprocessed pre-mRNAs; interacts with subunits of THO/TREX, TREX-2, and RNA polymerase II; contains a PIN (PilT N terminus) domain",".",".",".",".",".",".",".",".",".",".","."]
["EXOSC4","exosome component 4 [Source:HGNC Symbol;Acc:18189]","ENSG00000178896","ENSP00000315476",2,"RNase_PH[1],RNase_PH_C[1]","family-22","EXOSC4,EXOSC6","EXOSC4","EXOSC6[31,28]","diverse","diverse","established RBP ",".",".",".",".",1,".","GO:0017091,GO:0000175,GO:0000178,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928,GO:0071044,GO:0071028,GO:0000460,GO:0000956","AU-rich element binding,3'-5'-exoribonuclease activity,exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear mRNA surveillance,maturation of 5.8S rRNA,nuclear-transcribed mRNA catabolic process","GO:0005515,GO:0017091,GO:0000175,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0000178,GO:0035327,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0030307,GO:0051607,GO:0043928,GO:0071044,GO:0071028,GO:0000460,GO:0000956,GO:0045006","protein binding,AU-rich element binding,3'-5'-exoribonuclease activity,nucleus,cytoplasm,cytosol,nucleolus,exosome (RNase complex),transcriptionally active chromatin,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,positive regulation of cell growth,defense response to virus,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear mRNA surveillance,maturation of 5.8S rRNA,nuclear-transcribed mRNA catabolic process,DNA deamination","."]
["EXOSC6","exosome component 6 [Source:HGNC Symbol;Acc:19055]","ENSG00000223496","ENSP00000398597",1,"RNase_PH[1]","family-22","EXOSC4,EXOSC6","EXOSC4","EXOSC6[31,28]","diverse","diverse","established RBP ","nuclease",".",".",1,".",".","GO:0003723,GO:0000178,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","RNA binding,exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005829,GO:0005730,GO:0000178,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0045190,GO:0043928,GO:0045006","RNA binding,cytosol,nucleolus,exosome (RNase complex),gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,isotype switching,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,DNA deamination","."]
["PTRH1","peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:27039]","ENSG00000187024","ENSP00000439469",1,"Pept_tRNA_hydro[1]","family-220","PTRH1",".",".","tRNA","tRNA","established RBP ",".","novel",".",1,".",".","GO:0004045","aminoacyl-tRNA hydrolase activity","GO:0004045,GO:0005739","aminoacyl-tRNA hydrolase activity,mitochondrion","."]
["INTS8","integrator complex subunit 8 [Source:HGNC Symbol;Acc:26048]","ENSG00000164941","ENSP00000430338",".",".","family-221","INTS8",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0032039,GO:0016180","protein binding,integrator complex,snRNA processing","."]
["EXOSC10","exosome component 10 [Source:HGNC Symbol;Acc:9138]","ENSG00000171824","ENSP00000307307",3,"DNA_pol_A_exo1[1],HRDC[1],PMC2NT[1]","family-222","EXOSC10",".",".","diverse","diverse","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0008408,GO:0000176,GO:0006396,GO:0003723,GO:0004532,GO:0000178,GO:0071044,GO:0000184,GO:0071028,GO:0000460,GO:0000956,GO:0071034,GO:0071035,GO:0071048","3'-5' exonuclease activity,nuclear exosome (RNase complex),RNA processing,RNA binding,exoribonuclease activity,exosome (RNase complex),histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,nuclear mRNA surveillance,maturation of 5.8S rRNA,nuclear-transcribed mRNA catabolic process,CUT catabolic process,nuclear polyadenylation-dependent rRNA catabolic process,nuclear retention of unspliced pre-mRNA at the site of transcription","GO:0000166,GO:0003676,GO:0003824,GO:0008408,GO:0005634,GO:0005737,GO:0005622,GO:0005730,GO:0000176,GO:0006396,GO:0044237,GO:0006139,GO:0009048,GO:0003723,GO:0005515,GO:0004532,GO:0000178,GO:0035327,GO:0071044,GO:0000184,GO:0071028,GO:0000460,GO:0000956,GO:0071034,GO:0071035,GO:0071048","nucleotide binding,nucleic acid binding,catalytic activity,3'-5' exonuclease activity,nucleus,cytoplasm,intracellular,nucleolus,nuclear exosome (RNase complex),RNA processing,cellular metabolic process,nucleobase-containing compound metabolic process,dosage compensation by inactivation of X chromosome,RNA binding,protein binding,exoribonuclease activity,exosome (RNase complex),transcriptionally active chromatin,histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,nuclear mRNA surveillance,maturation of 5.8S rRNA,nuclear-transcribed mRNA catabolic process,CUT catabolic process,nuclear polyadenylation-dependent rRNA catabolic process,nuclear retention of unspliced pre-mRNA at the site of transcription","."]
["CASC3","cancer susceptibility candidate 3 [Source:HGNC Symbol;Acc:17040]","ENSG00000108349","ENSP00000264645",1,"Btz[1]","family-223","CASC3",".",".","mRNA","mRNA","The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0030529,GO:0016070,GO:0016071,GO:0006417,GO:0006397,GO:0008380,GO:0051028,GO:0000184,GO:0008298","RNA binding,ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,regulation of translation,mRNA processing,RNA splicing,mRNA transport,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,intracellular mRNA localization","GO:0005515,GO:0003723,GO:0031625,GO:0019899,GO:0042802,GO:0005737,GO:0005634,GO:0005829,GO:0048471,GO:0030529,GO:0016607,GO:0035145,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0006397,GO:0008380,GO:0006950,GO:0051028,GO:0000184,GO:0008298","protein binding,RNA binding,ubiquitin protein ligase binding,enzyme binding,identical protein binding,cytoplasm,nucleus,cytosol,perinuclear region of cytoplasm,ribonucleoprotein complex,nuclear speck,exon-exon junction complex,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,mRNA processing,RNA splicing,response to stress,mRNA transport,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,intracellular mRNA localization","."]
["GTF3A","general transcription factor IIIA [Source:HGNC Symbol;Acc:4662]","ENSG00000122034","ENSP00000370532",6,"zf-H2C2_2[2],zf-C2H2[4]","family-224","GTF3A",".",".","rRNA","rRNA","TFIIIA",".",".",".",".",".",1,"GO:0003723,GO:0009303","RNA binding,rRNA transcription","GO:0003676,GO:0046872,GO:0003723,GO:0003677,GO:0005634,GO:0005654,GO:0006355,GO:0010467,GO:0006383,GO:0009303","nucleic acid binding,metal ion binding,RNA binding,DNA binding,nucleus,nucleoplasm,regulation of transcription, DNA-dependent,gene expression,transcription from RNA polymerase III promoter,rRNA transcription","."]
["MRPL54","mitochondrial ribosomal protein L54 [Source:HGNC Symbol;Acc:16685]","ENSG00000183617","ENSP00000331849",1,"Ribosomal_L37[1]","family-225","MRPL54",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["GTPBP3","GTP binding protein 3 (mitochondrial) [Source:HGNC Symbol;Acc:14880]","ENSG00000130299","ENSP00000313818",3,"MMR_HSR1[1],GTPase_Cys_C[1],TrmE_N[1]","family-226","GTPBP3",".",".","tRNA","tRNA",18852288,".",".",".",".",".",".","GO:0006400","tRNA modification","GO:0005525,GO:0003924,GO:0005634,GO:0005739,GO:0006400","GTP binding,GTPase activity,nucleus,mitochondrion,tRNA modification"," DEAFNESS, AMINOGLYCOSIDE-INDUCED"]
["UBA1","ubiquitin-like modifier activating enzyme 1 [Source:HGNC Symbol;Acc:12469]","ENSG00000130985","ENSP00000366568",6,"UBACT[2],UBA_e1_C[1],UBA_e1_thiolCys[1],ThiF[2]","family-227","UBA1,UBA7,UBA6","UBA1","UBA7[43,45],UBA6[40,41]","mRNA","putative mRNA","22681889, 22658674, 23912277","candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005524,GO:0008641,GO:0006464,GO:0003824,GO:0005515,GO:0016874,GO:0016567,GO:0008219","ATP binding,small protein activating enzyme activity,cellular protein modification process,catalytic activity,protein binding,ligase activity,protein ubiquitination,cell death"," SPINAL MUSCULAR ATROPHY, X-LINKED 2; SMAX2"]
["LSM12","LSM12 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26407]","ENSG00000161654","ENSP00000293406",1,"AD[1]","family-228","LSM12",".",".","mRNA","mRNA/tRNA","established RBP ",".",".",".",".",".",".",".",".",".",".","."]
["HINT3","histidine triad nucleotide binding protein 3 [Source:HGNC Symbol;Acc:18468]","ENSG00000111911","ENSP00000229633",1,"DcpS_C[1]","family-229","HINT3",".",".","tRNA","putative tRNA",17870088,".",".",".",".",".",".",".",".","GO:0000166,GO:0003824,GO:0016787,GO:0005737,GO:0005739,GO:0005730","nucleotide binding,catalytic activity,hydrolase activity,cytoplasm,mitochondrion,nucleolus","."]
["CCDC59","coiled-coil domain containing 59 [Source:HGNC Symbol;Acc:25005]","ENSG00000133773","ENSP00000256151",1,"rRNA_processing[1]","family-23","CCDC59",".",".","unknown","unknown","established RBP ",".","novel",".",1,1,".",".",".","GO:0005515,GO:0005634,GO:0006351,GO:0006355","protein binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["POLDIP3","polymerase (DNA-directed), delta interacting protein 3 [Source:HGNC Symbol;Acc:23782]","ENSG00000100227","ENSP00000252116",1,"RRM_1[1]","family-230","POLDIP3",".",".","mRNA","mRNA","This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0045727,GO:0016973","RNA binding,positive regulation of translation,poly(A)+ mRNA export from nucleus","GO:0000166,GO:0003676,GO:0005634,GO:0043231,GO:0003723,GO:0005515,GO:0005737,GO:0016607,GO:0035145,GO:0000346,GO:0045727,GO:0016973","nucleotide binding,nucleic acid binding,nucleus,intracellular membrane-bounded organelle,RNA binding,protein binding,cytoplasm,nuclear speck,exon-exon junction complex,transcription export complex,positive regulation of translation,poly(A)+ mRNA export from nucleus","."]
["RPL32","ribosomal protein L32 [Source:HGNC Symbol;Acc:10336]","ENSG00000144713","ENSP00000339064",1,"Ribosomal_L32e[1]","family-231","RPL32",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,1,".","GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["AZGP1","alpha-2-glycoprotein 1, zinc-binding [Source:HGNC Symbol;Acc:910]","ENSG00000160862","ENSP00000292401",2,"C1-set[1],MHC_I[1]","family-232","AZGP1,HLA-F,HLA-C,HLA-E,HLA-B,HLA-G,HLA-A,MR1,FCGRT,HFE","AZGP1","HLA-F[36,24],HLA-C[37,30],HLA-E[34,28],HLA-B[39,32],HLA-G[37,33],HLA-A[38,31],MR1[34,30],FCGRT[27,22],HFE[36,31]","unknown","unknown",10462714,".",".",".",".",".",".","GO:0004540","ribonuclease activity","GO:0042605,GO:0042612,GO:0006955,GO:0019882,GO:0001916,GO:0002474,GO:0005515,GO:0003823,GO:0004540,GO:0008320,GO:0005886,GO:0005576,GO:0005615,GO:0008285,GO:0007155","peptide antigen binding,MHC class I protein complex,immune response,antigen processing and presentation,positive regulation of T cell mediated cytotoxicity,antigen processing and presentation of peptide antigen via MHC class I,protein binding,antigen binding,ribonuclease activity,protein transmembrane transporter activity,plasma membrane,extracellular region,extracellular space,negative regulation of cell proliferation,cell adhesion","."]
["EMG1","Ribosomal RNA small subunit methyltransferase NEP1  [Source:UniProtKB/Swiss-Prot;Acc:Q92979]","ENSG00000268439","ENSP00000470560",1,"EMG1[1]","family-233","EMG1",".",".","rRNA","rRNA","established RBP ","RNAbinding","novel",1,1,1,".","GO:0003723,GO:0019843,GO:0070037,GO:0006364,GO:0042274","RNA binding,rRNA binding,rRNA (pseudouridine) methyltransferase activity,rRNA processing,ribosomal small subunit biogenesis","GO:0003723,GO:0008168,GO:0019843,GO:0070037,GO:0005634,GO:0005737,GO:0005730,GO:0006364,GO:0042274","RNA binding,methyltransferase activity,rRNA binding,rRNA (pseudouridine) methyltransferase activity,nucleus,cytoplasm,nucleolus,rRNA processing,ribosomal small subunit biogenesis"," BOWEN-CONRADI SYNDROME; BWCNS"]
["C17orf85","chromosome 17 open reading frame 85 [Source:HGNC Symbol;Acc:24612]","ENSG00000074356","ENSP00000373657",1,"DUF2414[1]","family-234","C17orf85",".",".","unknown","unknown","established RBP ","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0000166","nucleotide binding","."]
["N4BP1","NEDD4 binding protein 1 [Source:HGNC Symbol;Acc:29850]","ENSG00000102921","ENSP00000262384",1,"RNase_Zc3h12a[1]","family-235","NYNRIN,N4BP1,KHNYN","NYNRIN","N4BP1[11,23],KHNYN[37,13]","unknown","unknown",17114934,".",".",".",".",".",".",".",".","GO:0005730,GO:0016605,GO:0034644,GO:0031397,GO:0032435,GO:0005515,GO:0005634","nucleolus,PML body,cellular response to UV,negative regulation of protein ubiquitination,negative regulation of proteasomal ubiquitin-dependent protein catabolic process,protein binding,nucleus","."]
["NYNRIN","NYN domain and retroviral integrase containing [Source:HGNC Symbol;Acc:20165]","ENSG00000205978","ENSP00000371994",2,"rve[1],RNase_Zc3h12a[1]","family-235","NYNRIN,N4BP1,KHNYN","NYNRIN","N4BP1[11,23],KHNYN[37,13]","unknown","unknown",17114934,".",".",".",".",".",".",".",".","GO:0003676,GO:0016021,GO:0015074","nucleic acid binding,integral to membrane,DNA integration","."]
["KHNYN","KH and NYN domain containing [Source:HGNC Symbol;Acc:20166]","ENSG00000100441","ENSP00000450799",1,"RNase_Zc3h12a[1]","family-235","NYNRIN,N4BP1,KHNYN","NYNRIN","N4BP1[11,23],KHNYN[37,13]","mRNA","mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["NOP2","NOP2 nucleolar protein [Source:HGNC Symbol;Acc:7867]","ENSG00000111641","ENSP00000371858",5,"P120R[3],GVQW[1],Nol1_Nop2_Fmu[1]","family-236","NOP2,NSUN3,NSUN6,NSUN4","NOP2","NSUN3[10,25],NSUN6[14,25],NSUN4[10,22]","rRNA","putative rRNA",23913415,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0006364","RNA binding,rRNA processing","GO:0008168,GO:0005634,GO:0005730,GO:0003723,GO:0005515,GO:0008757,GO:0008284,GO:0006364,GO:0032259","methyltransferase activity,nucleus,nucleolus,RNA binding,protein binding,S-adenosylmethionine-dependent methyltransferase activity,positive regulation of cell proliferation,rRNA processing,methylation","."]
["NSUN4","NOP2/Sun domain family, member 4 [Source:HGNC Symbol;Acc:31802]","ENSG00000117481","ENSP00000437758",1,"Nol1_Nop2_Fmu[1]","family-236","NOP2,NSUN3,NSUN6,NSUN4","NOP2","NSUN3[10,25],NSUN6[14,25],NSUN4[10,22]","rRNA","rRNA","22949673, 24516400",".",".",".",".",".",".","GO:0003723,GO:0005762,GO:0006364","RNA binding,mitochondrial large ribosomal subunit,rRNA processing","GO:0003723,GO:0005515,GO:0008168,GO:0005762,GO:0006364,GO:0005739","RNA binding,protein binding,methyltransferase activity,mitochondrial large ribosomal subunit,rRNA processing,mitochondrion","."]
["NSUN3","NOP2/Sun domain family, member 3 [Source:HGNC Symbol;Acc:26208]","ENSG00000178694","ENSP00000318986",1,"Nol1_Nop2_Fmu[1]","family-236","NOP2,NSUN3,NSUN6,NSUN4","NOP2","NSUN3[10,25],NSUN6[14,25],NSUN4[10,22]","unknown","unknown","established RBP ",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0008168","RNA binding,methyltransferase activity","."]
["NSUN6","NOP2/Sun domain family, member 6 [Source:HGNC Symbol;Acc:23529]","ENSG00000241058","ENSP00000366519",2,"PUA[1],Nol1_Nop2_Fmu[1]","family-236","NOP2,NSUN3,NSUN6,NSUN4","NOP2","NSUN3[10,25],NSUN6[14,25],NSUN4[10,22]","unknown","unknown","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0008168,GO:0032259","RNA binding,methyltransferase activity,methylation","."]
["PAN2","PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20074]","ENSG00000135473","ENSP00000257931",2,"RNase_T[1],UCH_1[1]","family-237","PAN2",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0004527,GO:0004535,GO:0000175,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0000184","exonuclease activity,poly(A)-specific ribonuclease activity,3'-5'-exoribonuclease activity,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0003676,GO:0004527,GO:0004535,GO:0004221,GO:0000175,GO:0005634,GO:0005829,GO:0000932,GO:0031251,GO:0006511,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0000184","protein binding,nucleic acid binding,exonuclease activity,poly(A)-specific ribonuclease activity,ubiquitin thiolesterase activity,3'-5'-exoribonuclease activity,nucleus,cytosol,cytoplasmic mRNA processing body,PAN complex,ubiquitin-dependent protein catabolic process,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["ZCCHC9","zinc finger, CCHC domain containing 9 [Source:HGNC Symbol;Acc:25424]","ENSG00000131732","ENSP00000369546",3,"zf-CCHC[3]","family-238","ZCCHC9",".",".","unknown","unknown","established RBP ",".","novel",".",1,1,".",".",".","GO:0008270,GO:0003676,GO:0010923","zinc ion binding,nucleic acid binding,negative regulation of phosphatase activity","."]
["RRP9","ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) [Source:HGNC Symbol;Acc:16829]","ENSG00000114767","ENSP00000232888",5,"WD40[5]","family-239","RRP9",".",".","snoRNA","snoRNA","This gene encodes a member of the WD-repeat protein family. The encoded protein is a component of the nucleolar small nuclear ribonucleoprotein particle (snoRNP) and is essential for 18s rRNA processing during ribosome synthesis. It contains seven WD domains required for nucleolar localization and specific interaction with the U3 small nucleolar RNA (U3 snoRNA). [provided by RefSeq, Oct 2012]","RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0030532,GO:0005732,GO:0006364","RNA binding,small nuclear ribonucleoprotein complex,small nucleolar ribonucleoprotein complex,rRNA processing","GO:0003723,GO:0005515,GO:0005634,GO:0030532,GO:0005732,GO:0006364","RNA binding,protein binding,nucleus,small nuclear ribonucleoprotein complex,small nucleolar ribonucleoprotein complex,rRNA processing","."]
["TNRC6A","trinucleotide repeat containing 6A [Source:HGNC Symbol;Acc:11969]","ENSG00000090905","ENSP00000326900",2,"RRM_5[1],Ago_hook[1]","family-24","TNRC6A,TNRC6B,TNRC6C","TNRC6A","TNRC6B[36,38],TNRC6C[39,44]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0031047,GO:0003723,GO:0000932,GO:0035068","gene silencing by RNA,RNA binding,cytoplasmic mRNA processing body,micro-ribonucleoprotein complex","GO:0000166,GO:0003676,GO:0031047,GO:0009267,GO:0005515,GO:0003723,GO:0005829,GO:0000932,GO:0035068,GO:0038095,GO:0045087,GO:0048015,GO:0010467,GO:0007219,GO:0008543,GO:0007173,GO:0048011,GO:0035278","nucleotide binding,nucleic acid binding,gene silencing by RNA,cellular response to starvation,protein binding,RNA binding,cytosol,cytoplasmic mRNA processing body,micro-ribonucleoprotein complex,Fc-epsilon receptor signaling pathway,innate immune response,phosphatidylinositol-mediated signaling,gene expression,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,negative regulation of translation involved in gene silencing by miRNA","."]
["TNRC6B","trinucleotide repeat containing 6B [Source:HGNC Symbol;Acc:29190]","ENSG00000100354","ENSP00000384795",2,"RRM_5[1],Ago_hook[1]","family-24","TNRC6A,TNRC6B,TNRC6C","TNRC6A","TNRC6B[36,38],TNRC6C[39,44]","mRNA","mRNA","established RBP ",".","RNAbinding",".",1,1,".","GO:0003723,GO:0000932,GO:0006417,GO:0031047,GO:0060213,GO:1900153","RNA binding,cytoplasmic mRNA processing body,regulation of translation,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","GO:0000166,GO:0003723,GO:0005515,GO:0005829,GO:0000932,GO:0038095,GO:0045087,GO:0048015,GO:0010467,GO:0006417,GO:0031047,GO:0060213,GO:1900153,GO:0007219,GO:0008543,GO:0007173,GO:0048011","nucleotide binding,RNA binding,protein binding,cytosol,cytoplasmic mRNA processing body,Fc-epsilon receptor signaling pathway,innate immune response,phosphatidylinositol-mediated signaling,gene expression,regulation of translation,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway","."]
["TNRC6C","trinucleotide repeat containing 6C [Source:HGNC Symbol;Acc:29318]","ENSG00000078687","ENSP00000440310",3,"RRM_5[1],M_domain[1],Ago_hook[1]","family-24","TNRC6A,TNRC6B,TNRC6C","TNRC6A","TNRC6B[36,38],TNRC6C[39,44]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0060964,GO:0003723,GO:0060213,GO:1900153","regulation of gene silencing by miRNA,RNA binding,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","GO:0000166,GO:0005515,GO:0003676,GO:0001706,GO:0035162,GO:0060964,GO:0003723,GO:0005829,GO:0038095,GO:0045087,GO:0048015,GO:0010467,GO:0060213,GO:1900153,GO:0007219,GO:0008543,GO:0007173,GO:0048011,GO:0035278,GO:0007492,GO:0048568","nucleotide binding,protein binding,nucleic acid binding,endoderm formation,embryonic hemopoiesis,regulation of gene silencing by miRNA,RNA binding,cytosol,Fc-epsilon receptor signaling pathway,innate immune response,phosphatidylinositol-mediated signaling,gene expression,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,negative regulation of translation involved in gene silencing by miRNA,endoderm development,embryonic organ development","."]
["RP9","retinitis pigmentosa 9 (autosomal dominant) [Source:HGNC Symbol;Acc:10288]","ENSG00000164610","ENSP00000297157",1,"Med19[1]","family-240","RP9",".",".","snRNA","snRNA",15541726,"candidate mRNA binder",".",".",1,".",".","GO:0008380","RNA splicing","GO:0008270,GO:0003676,GO:0005515,GO:0005634,GO:0005785,GO:0008380","zinc ion binding,nucleic acid binding,protein binding,nucleus,signal recognition particle receptor complex,RNA splicing"," RETINITIS PIGMENTOSA 9; RP9"]
["MRPL15","mitochondrial ribosomal protein L15 [Source:HGNC Symbol;Acc:14054]","ENSG00000137547","ENSP00000428581",1,"Ribosomal_L18e[1]","family-241","MRPL15",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0015934,GO:0006412","structural constituent of ribosome,large ribosomal subunit,translation","GO:0003735,GO:0005739,GO:0015934,GO:0006412","structural constituent of ribosome,mitochondrion,large ribosomal subunit,translation","."]
["NGDN","neuroguidin, EIF4E binding protein [Source:HGNC Symbol;Acc:20271]","ENSG00000129460","ENSP00000380340",1,"Sas10_Utp3[1]","family-242","NGDN",".",".","mRNA","mRNA","22727665, Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]","candidate mRNA binder","novel",1,1,1,".","GO:0006417","regulation of translation","GO:0005634,GO:0005737,GO:0030424,GO:0030425,GO:0030175,GO:0006417","nucleus,cytoplasm,axon,dendrite,filopodium,regulation of translation","."]
["LSM10","LSM10, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:17562]","ENSG00000181817","ENSP00000319341",1,"LSM[1]","family-243","LSM10",".",".","snRNA","snRNA",11574479,".",".",".",".",".",1,"GO:0071208,GO:0005683,GO:0008380,GO:0031124,GO:0008334","histone pre-mRNA DCP binding,U7 snRNP,RNA splicing,mRNA 3'-end processing,histone mRNA metabolic process","GO:0071208,GO:0005515,GO:0005654,GO:0015030,GO:0005683,GO:0006366,GO:0010467,GO:0008380,GO:0031124,GO:0000084,GO:0006369,GO:0008334","histone pre-mRNA DCP binding,protein binding,nucleoplasm,Cajal body,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA 3'-end processing,mitotic S phase,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["PUS1","pseudouridylate synthase 1 [Source:HGNC Symbol;Acc:15508]","ENSG00000177192","ENSP00000400032",2,"PseudoU_synth_1[2]","family-244","PUS1",".",".","tRNA","tRNA/snRNA U2/ SRA RNA",23707380,"RNAmod","RNAbinding",1,1,".",".","GO:0003723,GO:0008033,GO:0031119,GO:0009451","RNA binding,tRNA processing,tRNA pseudouridine synthesis,RNA modification","GO:0003723,GO:0003677,GO:0009982,GO:0030374,GO:0004730,GO:0005634,GO:0005667,GO:0005739,GO:0005730,GO:0045944,GO:0008033,GO:0001522,GO:0031119,GO:0009451,GO:0005515","RNA binding,DNA binding,pseudouridine synthase activity,ligand-dependent nuclear receptor transcription coactivator activity,pseudouridylate synthase activity,nucleus,transcription factor complex,mitochondrion,nucleolus,positive regulation of transcription from RNA polymerase II promoter,tRNA processing,pseudouridine synthesis,tRNA pseudouridine synthesis,RNA modification,protein binding"," MYOPATHY, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA 1; MLASA1"]
["MAK16","MAK16 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:13703]","ENSG00000198042","ENSP00000353246",2,"Mak16[1],Ribosomal_L28e[1]","family-245","MAK16",".",".","rRNA","rRNA","Essential nuclear protein; constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus",".","novel",".",1,1,".",".",".","GO:0005730","nucleolus","."]
["RPS13","ribosomal protein S13 [Source:HGNC Symbol;Acc:10386]","ENSG00000110700","ENSP00000435777",2,"Ribosomal_S13_N[1],Ribosomal_S15[1]","family-246","RPS13",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003729,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0033119,GO:0006415","structural constituent of ribosome,ribosome,translation,mRNA binding,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of RNA splicing,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0005515,GO:0003729,GO:0005634,GO:0005829,GO:0005622,GO:0005730,GO:0022627,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0033119,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,protein binding,mRNA binding,nucleus,cytosol,intracellular,nucleolus,cytosolic small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of RNA splicing,translational termination,viral transcription","."]
["SNRNP200","small nuclear ribonucleoprotein 200kDa (U5) [Source:HGNC Symbol;Acc:30859]","ENSG00000144028","ENSP00000317123",6,"Helicase_C[2],Sec63[2],DEAD[2]","family-247","ASCC3,SNRNP200","ASCC3","SNRNP200[39,40]","snRNA","snRNA","established RBP ","helicase","RNArelated",1,1,".",".","GO:0030529,GO:0004004,GO:0005681,GO:0071013,GO:0005682,GO:0008380,GO:0000398,GO:0000354","ribonucleoprotein complex,ATP-dependent RNA helicase activity,spliceosomal complex,catalytic step 2 spliceosome,U5 snRNP,RNA splicing,mRNA splicing, via spliceosome,cis assembly of pre-catalytic spliceosome","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0005634,GO:0004386,GO:0030529,GO:0019013,GO:0005515,GO:0042802,GO:0004004,GO:0005654,GO:0005681,GO:0071013,GO:0005682,GO:0010467,GO:0008380,GO:0000398,GO:0000354","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,nucleus,helicase activity,ribonucleoprotein complex,viral nucleocapsid,protein binding,identical protein binding,ATP-dependent RNA helicase activity,nucleoplasm,spliceosomal complex,catalytic step 2 spliceosome,U5 snRNP,gene expression,RNA splicing,mRNA splicing, via spliceosome,cis assembly of pre-catalytic spliceosome"," RETINITIS PIGMENTOSA 33; RP33"]
["PRDX1","peroxiredoxin 1 [Source:HGNC Symbol;Acc:9352]","ENSG00000117450","ENSP00000262746",2,"AhpC-TSA[1],1-cysPrx_C[1]","family-248","PRDX1,PRDX2,PRDX4,PRDX3","PRDX1","PRDX2[77,78],PRDX4[68,50],PRDX3[62,48]","mRNA","putative mRNA","22658674, 22681889, 22877757","metabolicEnz","novel",1,1,1,".",".",".","GO:0005515,GO:0042802,GO:0042803,GO:0016491,GO:0004601,GO:0020037,GO:0016209,GO:0051920,GO:0008379,GO:0005739,GO:0005737,GO:0005634,GO:0005829,GO:0005759,GO:0005730,GO:0042470,GO:0005782,GO:0005719,GO:0000302,GO:0006979,GO:0008283,GO:0042744,GO:0055114,GO:0001501,GO:0019430,GO:0042267,GO:0034101,GO:0032872,GO:0042345","protein binding,identical protein binding,protein homodimerization activity,oxidoreductase activity,peroxidase activity,heme binding,antioxidant activity,peroxiredoxin activity,thioredoxin peroxidase activity,mitochondrion,cytoplasm,nucleus,cytosol,mitochondrial matrix,nucleolus,melanosome,peroxisomal matrix,nuclear euchromatin,response to reactive oxygen species,response to oxidative stress,cell proliferation,hydrogen peroxide catabolic process,oxidation-reduction process,skeletal system development,removal of superoxide radicals,natural killer cell mediated cytotoxicity,erythrocyte homeostasis,regulation of stress-activated MAPK cascade,regulation of NF-kappaB import into nucleus","."]
["TSN","translin [Source:HGNC Symbol;Acc:12379]","ENSG00000211460","ENSP00000399735",1,"Translin[1]","family-249","TSN",".",".","tRNA","tRNA",22773104,".",".",".",".",".",".","GO:0003729,GO:0003723","mRNA binding,RNA binding","GO:0005515,GO:0003677,GO:0004519,GO:0043565,GO:0003729,GO:0005634,GO:0005737,GO:0006310,GO:0003723,GO:0032403","protein binding,DNA binding,endonuclease activity,sequence-specific DNA binding,mRNA binding,nucleus,cytoplasm,DNA recombination,RNA binding,protein complex binding","."]
["NUFIP2","nuclear fragile X mental retardation protein interacting protein 2 [Source:HGNC Symbol;Acc:17634]","ENSG00000108256","ENSP00000225388",1,"NUFIP2[1]","family-25","NUFIP2",".",".","mRNA","mRNA",12837692,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0042788","RNA binding,polysomal ribosome","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0042788","RNA binding,protein binding,nucleus,cytoplasm,polysomal ribosome","."]
["RBM19","RNA binding motif protein 19 [Source:HGNC Symbol;Acc:29098]","ENSG00000122965","ENSP00000442053",6,"RRM_1[4],RRM_6[2]","family-250","RBM19",".",".","rRNA","putative rRNA","MRD1 yeast homolog ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0005694,GO:0005730,GO:0005654,GO:0007275,GO:0040019","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,chromosome,nucleolus,nucleoplasm,multicellular organismal development,positive regulation of embryonic development","."]
["TDRKH","tudor and KH domain containing [Source:HGNC Symbol;Acc:11713]","ENSG00000182134","ENSP00000357812",3,"TUDOR[1],KH_1[2]","family-251","TDRKH",".",".","ncRNA","piRNA",23714778,".",".",".",".",".",1,"GO:0003723,GO:0071546,GO:0071547,GO:0031047,GO:0034587","RNA binding,pi-body,piP-body,gene silencing by RNA,piRNA metabolic process","GO:0005739,GO:0003723,GO:0071546,GO:0071547,GO:0030154,GO:0007283,GO:0007140,GO:0009566,GO:0031047,GO:0034587,GO:0043046,GO:0005515,GO:0005737","mitochondrion,RNA binding,pi-body,piP-body,cell differentiation,spermatogenesis,male meiosis,fertilization,gene silencing by RNA,piRNA metabolic process,DNA methylation involved in gamete generation,protein binding,cytoplasm","."]
["NOP58","NOP58 ribonucleoprotein [Source:HGNC Symbol;Acc:29926]","ENSG00000055044","ENSP00000264279",3,"NOP5NT[1],Nop[1],NOSIC[1]","family-252","NOP58",".",".","snoRNA","snoRNA",10606270,"RNAbinding","RNAbinding",1,1,1,".","GO:0030515,GO:0005732,GO:0031428,GO:0070761,GO:0006608,GO:0006364","snoRNA binding,small nucleolar ribonucleoprotein complex,box C/D snoRNP complex,pre-snoRNP complex,snRNP protein import into nucleus,rRNA processing","GO:0005515,GO:0030515,GO:0005732,GO:0005634,GO:0005737,GO:0005730,GO:0015030,GO:0031428,GO:0070761,GO:0006608,GO:0006364,GO:0016049","protein binding,snoRNA binding,small nucleolar ribonucleoprotein complex,nucleus,cytoplasm,nucleolus,Cajal body,box C/D snoRNP complex,pre-snoRNP complex,snRNP protein import into nucleus,rRNA processing,cell growth","."]
["RBM6","RNA binding motif protein 6 [Source:HGNC Symbol;Acc:9903]","ENSG00000004534","ENSP00000266022",3,"G-patch[1],RRM_6[2]","family-253","RBM10,RBM5,RBM6","RBM10","RBM5[48,55],RBM6[23,19]","mRNA","putative mRNA","by homology","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0000166,GO:0003676,GO:0005634,GO:0003723,GO:0003677,GO:0006396","nucleotide binding,nucleic acid binding,nucleus,RNA binding,DNA binding,RNA processing","."]
["RBM10","RNA binding motif protein 10 [Source:HGNC Symbol;Acc:9896]","ENSG00000182872","ENSP00000328848",4,"G-patch[1],zf-RanBP[1],RRM_6[2]","family-253","RBM10,RBM5,RBM6","RBM10","RBM5[48,55],RBM6[23,19]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0070935","RNA binding,mRNA processing,RNA splicing,3'-UTR-mediated mRNA stabilization","GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0046872,GO:0042802,GO:0032403,GO:0005634,GO:0000122,GO:0008285,GO:0006397,GO:0008380,GO:0034393,GO:0070935,GO:0034391","nucleotide binding,RNA binding,protein binding,zinc ion binding,nucleic acid binding,metal ion binding,identical protein binding,protein complex binding,nucleus,negative regulation of transcription from RNA polymerase II promoter,negative regulation of cell proliferation,mRNA processing,RNA splicing,positive regulation of smooth muscle cell apoptotic process,3'-UTR-mediated mRNA stabilization,regulation of smooth muscle cell apoptotic process"," TARP SYNDROME; TARPS"]
["RBM5","RNA binding motif protein 5 [Source:HGNC Symbol;Acc:9902]","ENSG00000003756","ENSP00000343054",4,"G-patch[1],zf-RanBP[1],RRM_6[2]","family-253","RBM10,RBM5,RBM6","RBM10","RBM5[48,55],RBM6[23,19]","mRNA","mRNA","This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011]","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0003729,GO:0005681,GO:0008380,GO:0000381,GO:0000398,GO:0006396,GO:0000245","RNA binding,mRNA binding,spliceosomal complex,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,RNA processing,spliceosomal complex assembly","GO:0005634,GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003677,GO:0003729,GO:0005654,GO:0005681,GO:0006915,GO:0008285,GO:0010467,GO:0008380,GO:0000381,GO:0000398,GO:0043065,GO:0006396,GO:0000245,GO:0003676,GO:0046872","nucleus,nucleotide binding,RNA binding,protein binding,zinc ion binding,DNA binding,mRNA binding,nucleoplasm,spliceosomal complex,apoptotic process,negative regulation of cell proliferation,gene expression,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,positive regulation of apoptotic process,RNA processing,spliceosomal complex assembly,nucleic acid binding,metal ion binding","."]
["RBM44","RNA binding motif protein 44 [Source:HGNC Symbol;Acc:24756]","ENSG00000177483","ENSP00000321179",1,"RRM_1[1]","family-254","RBM44",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0005515,GO:0042803,GO:0000166,GO:0003723,GO:0003676,GO:0005737,GO:0045171","protein binding,protein homodimerization activity,nucleotide binding,RNA binding,nucleic acid binding,cytoplasm,intercellular bridge","."]
["OASL","2'-5'-oligoadenylate synthetase-like [Source:HGNC Symbol;Acc:8090]","ENSG00000135114","ENSP00000257570",2,"OAS1_C[1],ubiquitin[1]","family-255","OAS1,OAS3,OAS2,OASL","OAS1","OAS3[49,19],OAS2[45,26],OASL[36,29]","ncRNA","2-5A oligo",22531715,".","RNAbinding",".",1,".",".","GO:0003723,GO:0003725","RNA binding,double-stranded RNA binding","GO:0003723,GO:0005524,GO:0003677,GO:0016740,GO:0003725,GO:0046966,GO:0005737,GO:0005829,GO:0005730,GO:0009615,GO:0006955,GO:0045071,GO:0019221,GO:0051607,GO:0060333,GO:0060337,GO:0005515","RNA binding,ATP binding,DNA binding,transferase activity,double-stranded RNA binding,thyroid hormone receptor binding,cytoplasm,cytosol,nucleolus,response to virus,immune response,negative regulation of viral genome replication,cytokine-mediated signaling pathway,defense response to virus,interferon-gamma-mediated signaling pathway,type I interferon signaling pathway,protein binding","."]
["OAS1","2'-5'-oligoadenylate synthetase 1, 40/46kDa [Source:HGNC Symbol;Acc:8086]","ENSG00000089127","ENSP00000448790",2,"NTP_transf_2[1],OAS1_C[1]","family-255","OAS1,OAS3,OAS2,OASL","OAS1","OAS3[49,19],OAS2[45,26],OASL[36,29]","ncRNA","2-5A oligo","This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003725,GO:0003723,GO:0060700","double-stranded RNA binding,RNA binding,regulation of ribonuclease activity","GO:0005524,GO:0016740,GO:0003725,GO:0006955,GO:0051607,GO:0003723,GO:0016779,GO:0005515,GO:0008270,GO:0046872,GO:0001730,GO:0005634,GO:0005737,GO:0005576,GO:0005739,GO:0005829,GO:0005783,GO:0009615,GO:0045071,GO:0019221,GO:0006164,GO:0060333,GO:0051259,GO:0035457,GO:0060337,GO:0060700","ATP binding,transferase activity,double-stranded RNA binding,immune response,defense response to virus,RNA binding,nucleotidyltransferase activity,protein binding,zinc ion binding,metal ion binding,2'-5'-oligoadenylate synthetase activity,nucleus,cytoplasm,extracellular region,mitochondrion,cytosol,endoplasmic reticulum,response to virus,negative regulation of viral genome replication,cytokine-mediated signaling pathway,purine nucleotide biosynthetic process,interferon-gamma-mediated signaling pathway,protein oligomerization,cellular response to interferon-alpha,type I interferon signaling pathway,regulation of ribonuclease activity","."]
["OAS2","2'-5'-oligoadenylate synthetase 2, 69/71kDa [Source:HGNC Symbol;Acc:8087]","ENSG00000111335","ENSP00000376362",3,"OAS1_C[2],NTP_transf_2[1]","family-255","OAS1,OAS3,OAS2,OASL","OAS1","OAS3[49,19],OAS2[45,26],OASL[36,29]","ncRNA","2-5A oligo","This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0003725,GO:0006401","RNA binding,double-stranded RNA binding,RNA catabolic process","GO:0003723,GO:0005524,GO:0016740,GO:0003725,GO:0006955,GO:0051607,GO:0008270,GO:0046872,GO:0001730,GO:0005634,GO:0005737,GO:0005739,GO:0016020,GO:0005829,GO:0048471,GO:0005783,GO:0043231,GO:0009615,GO:0006486,GO:0019221,GO:0006139,GO:0006164,GO:0060333,GO:0006401,GO:0060337,GO:0018377,GO:0016779","RNA binding,ATP binding,transferase activity,double-stranded RNA binding,immune response,defense response to virus,zinc ion binding,metal ion binding,2'-5'-oligoadenylate synthetase activity,nucleus,cytoplasm,mitochondrion,membrane,cytosol,perinuclear region of cytoplasm,endoplasmic reticulum,intracellular membrane-bounded organelle,response to virus,protein glycosylation,cytokine-mediated signaling pathway,nucleobase-containing compound metabolic process,purine nucleotide biosynthetic process,interferon-gamma-mediated signaling pathway,RNA catabolic process,type I interferon signaling pathway,protein myristoylation,nucleotidyltransferase activity","."]
["OAS3","2'-5'-oligoadenylate synthetase 3, 100kDa [Source:HGNC Symbol;Acc:8088]","ENSG00000111331","ENSP00000228928",4,"OAS1_C[3],NTP_transf_2[1]","family-255","OAS1,OAS3,OAS2,OASL","OAS1","OAS3[49,19],OAS2[45,26],OASL[36,29]","ncRNA","2-5A oligo","This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0003725,GO:0060700","RNA binding,double-stranded RNA binding,regulation of ribonuclease activity","GO:0003723,GO:0005524,GO:0016740,GO:0003725,GO:0006955,GO:0051607,GO:0001730,GO:0005515,GO:0046872,GO:0016779,GO:0005634,GO:0005737,GO:0005829,GO:0043231,GO:0009615,GO:0045071,GO:0019221,GO:0006139,GO:0060333,GO:0060337,GO:0060700","RNA binding,ATP binding,transferase activity,double-stranded RNA binding,immune response,defense response to virus,2'-5'-oligoadenylate synthetase activity,protein binding,metal ion binding,nucleotidyltransferase activity,nucleus,cytoplasm,cytosol,intracellular membrane-bounded organelle,response to virus,negative regulation of viral genome replication,cytokine-mediated signaling pathway,nucleobase-containing compound metabolic process,interferon-gamma-mediated signaling pathway,type I interferon signaling pathway,regulation of ribonuclease activity","."]
["SF3A3","splicing factor 3a, subunit 3, 60kDa [Source:HGNC Symbol;Acc:10767]","ENSG00000183431","ENSP00000362110",3,"Telomere_Sde2_2[1],SF3a60_bindingd[1],DUF3449[1]","family-256","SF3A3",".",".","snRNA","snRNA","This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,1,".","GO:0005681,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0000375,GO:0000389","spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,mRNA 3'-splice site recognition","GO:0008270,GO:0003676,GO:0005634,GO:0005515,GO:0005654,GO:0005681,GO:0016607,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0000375,GO:0000389","zinc ion binding,nucleic acid binding,nucleus,protein binding,nucleoplasm,spliceosomal complex,nuclear speck,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,mRNA 3'-splice site recognition","."]
["NOC3L","nucleolar complex associated 3 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24034]","ENSG00000173145","ENSP00000360401",2,"CBF[1],NOC3p[1]","family-257","NOC3L",".",".","rRNA","putative rRNA","NOC3 homolog yeast","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005488,GO:0005730,GO:0016607,GO:0045444","binding,nucleolus,nuclear speck,fat cell differentiation","."]
["MYEF2","myelin expression factor 2 [Source:HGNC Symbol;Acc:17940]","ENSG00000104177","ENSP00000267836",3,"RRM_1[3]","family-258","HNRNPM,MYEF2","HNRNPM","MYEF2[42,52]","mRNA","putative mRNA","by domain","RNAbinding",".",".",1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003677,GO:0005634,GO:0005794,GO:0006351,GO:0030182,GO:0014902,GO:0003676","nucleotide binding,RNA binding,DNA binding,nucleus,Golgi apparatus,transcription, DNA-templated,neuron differentiation,myotube differentiation,nucleic acid binding","."]
["HNRNPM","heterogeneous nuclear ribonucleoprotein M [Source:HGNC Symbol;Acc:5046]","ENSG00000099783","ENSP00000325376",4,"HnRNP_M[1],RRM_1[3]","family-258","HNRNPM,MYEF2","HNRNPM","MYEF2[42,52]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0000398,GO:0005681,GO:0071013,GO:0008380,GO:0000380","RNA binding,mRNA splicing, via spliceosome,spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,alternative mRNA splicing, via spliceosome","GO:0003676,GO:0003723,GO:0000398,GO:0000166,GO:0005515,GO:0019904,GO:0005634,GO:0005887,GO:0005654,GO:0005681,GO:0016363,GO:0071013,GO:0042382,GO:0010467,GO:0008380,GO:0000380","nucleic acid binding,RNA binding,mRNA splicing, via spliceosome,nucleotide binding,protein binding,protein domain specific binding,nucleus,integral to plasma membrane,nucleoplasm,spliceosomal complex,nuclear matrix,catalytic step 2 spliceosome,paraspeckles,gene expression,RNA splicing,alternative mRNA splicing, via spliceosome","."]
["C11orf68","chromosome 11 open reading frame 68 [Source:HGNC Symbol;Acc:28801]","ENSG00000175573","ENSP00000398350",1,"DUF1917[1]","family-259","C11orf68",".",".","unknown","unknown","22658674, 22681889","candidate mRNA binder","RNAbinding",1,1,1,".",".",".",".",".","."]
["MRPL10","mitochondrial ribosomal protein L10 [Source:HGNC Symbol;Acc:14055]","ENSG00000159111","ENSP00000324100",1,"Ribosomal_L10[1]","family-26","MRPL10",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0030529,GO:0005762,GO:0006412,GO:0042254","structural constituent of ribosome,ribonucleoprotein complex,mitochondrial large ribosomal subunit,translation,ribosome biogenesis","GO:0003735,GO:0005739,GO:0005622,GO:0030529,GO:0005762,GO:0006412,GO:0042254","structural constituent of ribosome,mitochondrion,intracellular,ribonucleoprotein complex,mitochondrial large ribosomal subunit,translation,ribosome biogenesis","."]
["RNASE10","ribonuclease, RNase A family, 10 (non-active) [Source:HGNC Symbol;Acc:19275]","ENSG00000182545","ENSP00000392996",1,"RnaseA[1]","family-260","RNASE10",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016892,GO:0005576,GO:0022409,GO:0034113,GO:0080154,GO:1902093","nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region,positive regulation of cell-cell adhesion,heterotypic cell-cell adhesion,regulation of fertilization,positive regulation of sperm motility","."]
["CALR","calreticulin [Source:HGNC Symbol;Acc:1455]","ENSG00000179218","ENSP00000465105",1,"Calreticulin[1]","family-261","CALR,CALR3,CANX,CLGN","CALR","CALR3[45,49],CANX[42,30],CLGN[38,26]","mRNA","mRNA","18413143, 7809119",".","RNAbinding",".",1,".",".","GO:0003729","mRNA binding","GO:0005515,GO:0005509,GO:0051082,GO:0005783,GO:0006457,GO:0030246,GO:0003729,GO:0001948,GO:0008270,GO:0003677,GO:0051087,GO:0005506,GO:0031625,GO:0005178,GO:0042277,GO:0050681,GO:0042562,GO:0044183,GO:0001849,GO:0005844,GO:0042824,GO:0031012,GO:0048471,GO:0005615,GO:0043234,GO:0043231,GO:0005634,GO:0005737,GO:0009986,GO:0016529,GO:0005576,GO:0005829,GO:0005622,GO:0005794,GO:0005578,GO:0009897,GO:0001669,GO:0005788,GO:0033018,GO:0071556,GO:0071682,GO:0050821,GO:0045787,GO:0034504,GO:0050766,GO:0090398,GO:0002502,GO:0017148,GO:0061077,GO:0071310,GO:0010033,GO:0000122,GO:0042981,GO:0007283,GO:0045892,GO:0006611,GO:0002474,GO:0006355,GO:0008284,GO:0048387,GO:0042493,GO:0002479,GO:0042590,GO:0010628,GO:0007050,GO:0045665,GO:0032355,GO:0055007,GO:0033574,GO:0045740,GO:0030866,GO:0044267,GO:0006874,GO:0030968,GO:0043687,GO:0033144,GO:1900026,GO:0071285,GO:0018279,GO:2000510,GO:0022417,GO:0042921,GO:0006987,GO:0051208,GO:0040020","protein binding,calcium ion binding,unfolded protein binding,endoplasmic reticulum,protein folding,carbohydrate binding,mRNA binding,glycoprotein binding,zinc ion binding,DNA binding,chaperone binding,iron ion binding,ubiquitin protein ligase binding,integrin binding,peptide binding,androgen receptor binding,hormone binding,protein binding involved in protein folding,complement component C1q binding,polysome,MHC class I peptide loading complex,extracellular matrix,perinuclear region of cytoplasm,extracellular space,protein complex,intracellular membrane-bounded organelle,nucleus,cytoplasm,cell surface,sarcoplasmic reticulum,extracellular region,cytosol,intracellular,Golgi apparatus,proteinaceous extracellular matrix,external side of plasma membrane,acrosomal vesicle,endoplasmic reticulum lumen,sarcoplasmic reticulum lumen,integral to lumenal side of endoplasmic reticulum membrane,endocytic vesicle lumen,protein stabilization,positive regulation of cell cycle,protein localization to nucleus,positive regulation of phagocytosis,cellular senescence,peptide antigen assembly with MHC class I protein complex,negative regulation of translation,chaperone-mediated protein folding,cellular response to organic substance,response to organic substance,negative regulation of transcription from RNA polymerase II promoter,regulation of apoptotic process,spermatogenesis,negative regulation of transcription, DNA-dependent,protein export from nucleus,antigen processing and presentation of peptide antigen via MHC class I,regulation of transcription, DNA-dependent,positive regulation of cell proliferation,negative regulation of retinoic acid receptor signaling pathway,response to drug,antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent,antigen processing and presentation of exogenous peptide antigen via MHC class I,positive regulation of gene expression,cell cycle arrest,negative regulation of neuron differentiation,response to estradiol,cardiac muscle cell differentiation,response to testosterone,positive regulation of DNA replication,cortical actin cytoskeleton organization,cellular protein metabolic process,cellular calcium ion homeostasis,endoplasmic reticulum unfolded protein response,post-translational protein modification,negative regulation of intracellular steroid hormone receptor signaling pathway,positive regulation of substrate adhesion-dependent cell spreading,cellular response to lithium ion,protein N-linked glycosylation via asparagine,positive regulation of dendritic cell chemotaxis,protein maturation by protein folding,glucocorticoid receptor signaling pathway,activation of signaling protein activity involved in unfolded protein response,sequestering of calcium ion,regulation of meiosis","."]
["CANX","calnexin [Source:HGNC Symbol;Acc:1473]","ENSG00000127022","ENSP00000391646",2,"DUF1510[1],Calreticulin[1]","family-261","CALR,CALR3,CANX,CLGN","CALR","CALR3[45,49],CANX[42,30],CLGN[38,26]","unknown","unknown","22658674, 22681889","candidate mRNA binder","RNArelated",1,1,".",".","GO:0005840","ribosome","GO:0005515,GO:0005509,GO:0035255,GO:0051082,GO:0034185,GO:0016021,GO:0030424,GO:0005783,GO:0005840,GO:0043025,GO:0043197,GO:0032839,GO:0006457,GO:0007568,GO:0048488,GO:0072583,GO:0005789,GO:0042470,GO:0005788,GO:0071556,GO:0002474,GO:0009306,GO:0044267,GO:0043687,GO:0018279,GO:0019886,GO:0001948,GO:0043234,GO:0005737,GO:0061077","protein binding,calcium ion binding,ionotropic glutamate receptor binding,unfolded protein binding,apolipoprotein binding,integral to membrane,axon,endoplasmic reticulum,ribosome,neuronal cell body,dendritic spine,dendrite cytoplasm,protein folding,aging,synaptic vesicle endocytosis,clathrin-mediated endocytosis,endoplasmic reticulum membrane,melanosome,endoplasmic reticulum lumen,integral to lumenal side of endoplasmic reticulum membrane,antigen processing and presentation of peptide antigen via MHC class I,protein secretion,cellular protein metabolic process,post-translational protein modification,protein N-linked glycosylation via asparagine,antigen processing and presentation of exogenous peptide antigen via MHC class II,glycoprotein binding,protein complex,cytoplasm,chaperone-mediated protein folding","."]
["CALR3","calreticulin 3 [Source:HGNC Symbol;Acc:20407]","ENSG00000269058","ENSP00000269881",1,"Calreticulin[1]","family-261","CALR,CALR3,CANX,CLGN","CALR","CALR3[45,49],CANX[42,30],CLGN[38,26]","unknown","unknown","by homology",".",".",".",".",".",".",".",".","GO:0005509,GO:0051082,GO:0005783,GO:0006457,GO:0005515,GO:0005788,GO:0030154,GO:0007283","calcium ion binding,unfolded protein binding,endoplasmic reticulum,protein folding,protein binding,endoplasmic reticulum lumen,cell differentiation,spermatogenesis"," CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 19; CMH19"]
["RPP14","ribonuclease P/MRP 14kDa subunit [Source:HGNC Symbol;Acc:30327]","ENSG00000163684","ENSP00000412894",1,"RNase_P_Rpp14[1]","family-262","RPP14",".",".","ncRNA","MRP RNA",10024167,".",".",".",".",".",".","GO:0003723,GO:0004540,GO:0004526,GO:0008033","RNA binding,ribonuclease activity,ribonuclease P activity,tRNA processing","GO:0016491,GO:0016829,GO:0005739,GO:0008152,GO:0006631,GO:0003723,GO:0004540,GO:0004526,GO:0005634,GO:0008033","oxidoreductase activity,lyase activity,mitochondrion,metabolic process,fatty acid metabolic process,RNA binding,ribonuclease activity,ribonuclease P activity,nucleus,tRNA processing","."]
["RPS8","ribosomal protein S8 [Source:HGNC Symbol;Acc:10441]","ENSG00000142937","ENSP00000379888",1,"Ribosomal_S8e[1]","family-263","RPS8",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0030529,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0000462","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0003735,GO:0005737,GO:0005840,GO:0006412,GO:0022627,GO:0005829,GO:0005622,GO:0030529,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0000462","structural constituent of ribosome,cytoplasm,ribosome,translation,cytosolic small ribosomal subunit,cytosol,intracellular,ribonucleoprotein complex,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["PDCD7","programmed cell death 7 [Source:HGNC Symbol;Acc:8767]","ENSG00000090470","ENSP00000204549",".",".","family-264","PDCD7",".",".","snRNA","snRNA","This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010]",".",".",".",".",".",".","GO:0005689,GO:0008380","U12-type spliceosomal complex,RNA splicing","GO:0005689,GO:2001235,GO:0070234,GO:0006915,GO:0008380,GO:0051384","U12-type spliceosomal complex,positive regulation of apoptotic signaling pathway,positive regulation of T cell apoptotic process,apoptotic process,RNA splicing,response to glucocorticoid","."]
["RPS19BP1","ribosomal protein S19 binding protein 1 [Source:HGNC Symbol;Acc:28749]","ENSG00000187051","ENSP00000333948",".",".","family-265","RPS19BP1",".",".","unknown","RNA related",16289379,"candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005730,GO:0005654,GO:0005737","protein binding,nucleolus,nucleoplasm,cytoplasm","."]
["TRMT6","tRNA methyltransferase 6 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20900]","ENSG00000089195","ENSP00000203001",1,"Gcd10p[1]","family-266","TRMT6",".",".","tRNA","putative tRNA","This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]",".","RNArelated",".",1,".",".","GO:0003743,GO:0006413,GO:0008033,GO:0006446","translation initiation factor activity,translational initiation,tRNA processing,regulation of translational initiation","GO:0008168,GO:0003743,GO:0006413,GO:0005634,GO:0008033,GO:0006446","methyltransferase activity,translation initiation factor activity,translational initiation,nucleus,tRNA processing,regulation of translational initiation","."]
["RPL4","ribosomal protein L4 [Source:HGNC Symbol;Acc:10353]","ENSG00000174444","ENSP00000454281",2,"Ribosomal_L4[1],Ribos_L4_asso_C[1]","family-267","RPL4",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0030529,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,ribonucleoprotein complex,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0005515,GO:0003723,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0030529,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,protein binding,RNA binding,nucleus,cytoplasm,cytosol,nucleolus,ribonucleoprotein complex,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["PRPF3","PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17348]","ENSG00000265228","ENSP00000463374",3,"DUF1115[1],PRP3[1],PWI[1]","family-268","PRPF3",".",".","snRNA","snRNA/mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0046540,GO:0000398,GO:0006397,GO:0005681,GO:0008380,GO:0000375","U4/U6 x U5 tri-snRNP complex,mRNA splicing, via spliceosome,mRNA processing,spliceosomal complex,RNA splicing,RNA splicing, via transesterification reactions","GO:0019013,GO:0046540,GO:0000398,GO:0005634,GO:0005737,GO:0006397,GO:0005515,GO:0042802,GO:0005681,GO:0016607,GO:0015030,GO:0008380,GO:0000375","viral nucleocapsid,U4/U6 x U5 tri-snRNP complex,mRNA splicing, via spliceosome,nucleus,cytoplasm,mRNA processing,protein binding,identical protein binding,spliceosomal complex,nuclear speck,Cajal body,RNA splicing,RNA splicing, via transesterification reactions"," RETINITIS PIGMENTOSA 18; RP18"]
["RARS","arginyl-tRNA synthetase [Source:HGNC Symbol;Acc:9870]","ENSG00000113643","ENSP00000231572",3,"tRNA-synt_1d[1],Arg_tRNA_synt_N[1],DALR_1[1]","family-269","RARS,RARS2","RARS","RARS2[25,29]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000049,GO:0004812,GO:0004814,GO:0017101,GO:0006418,GO:0006420","tRNA binding,aminoacyl-tRNA ligase activity,arginine-tRNA ligase activity,aminoacyl-tRNA synthetase multienzyme complex,tRNA aminoacylation for protein translation,arginyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0000049,GO:0004812,GO:0004814,GO:0034618,GO:0005634,GO:0005737,GO:0005739,GO:0017101,GO:0006418,GO:0006420,GO:0005515,GO:0005829,GO:0010467","nucleotide binding,ATP binding,tRNA binding,aminoacyl-tRNA ligase activity,arginine-tRNA ligase activity,arginine binding,nucleus,cytoplasm,mitochondrion,aminoacyl-tRNA synthetase multienzyme complex,tRNA aminoacylation for protein translation,arginyl-tRNA aminoacylation,protein binding,cytosol,gene expression","."]
["RARS2","arginyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:21406]","ENSG00000146282","ENSP00000389656",2,"GVQW[1],tRNA-synt_1d[1]","family-269","RARS,RARS2","RARS","RARS2[25,29]","tRNA","tRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0004814,GO:0006420,GO:0004812,GO:0006418","arginine-tRNA ligase activity,arginyl-tRNA aminoacylation,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation","GO:0000166,GO:0005524,GO:0004814,GO:0005737,GO:0006420,GO:0004812,GO:0005739,GO:0005759,GO:0010467,GO:0006418","nucleotide binding,ATP binding,arginine-tRNA ligase activity,cytoplasm,arginyl-tRNA aminoacylation,aminoacyl-tRNA ligase activity,mitochondrion,mitochondrial matrix,gene expression,tRNA aminoacylation for protein translation"," PONTOCEREBELLAR HYPOPLASIA, TYPE 6; PCH6"]
["APOBEC4","apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) [Source:HGNC Symbol;Acc:32152]","ENSG00000173627","ENSP00000310622",1,"APOBEC_N[1]","family-27","APOBEC4",".",".","mRNA","putative mRNA","established RBP ",".",".",".",".",".",".","GO:0006397","mRNA processing","GO:0008270,GO:0016814,GO:0006397","zinc ion binding,hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines,mRNA processing","."]
["ZCCHC24","zinc finger, CCHC domain containing 24 [Source:HGNC Symbol;Acc:26911]","ENSG00000165424","ENSP00000361411",2,"zf-3CxxC[1],zf-CCHC_2[1]","family-270","ZCCHC24",".",".","unknown","unknown","established RBP ","candidate mRNA binder",".",".",1,".",".",".",".","GO:0008270,GO:0003676","zinc ion binding,nucleic acid binding","."]
["RPS21","ribosomal protein S21 [Source:HGNC Symbol;Acc:10409]","ENSG00000171858","ENSP00000388332",1,"Ribosomal_S21e[1]","family-271","RPS21",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0015935,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0000447,GO:0006415,GO:0042274,GO:0000461","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),translational termination,ribosomal small subunit biogenesis,endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0003735,GO:0005737,GO:0005622,GO:0005840,GO:0006412,GO:0047485,GO:0005829,GO:0022627,GO:0015935,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0000447,GO:0006415,GO:0019083,GO:0042274,GO:0000461","structural constituent of ribosome,cytoplasm,intracellular,ribosome,translation,protein N-terminus binding,cytosol,cytosolic small ribosomal subunit,small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),translational termination,viral transcription,ribosomal small subunit biogenesis,endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["DDX24","DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 [Source:HGNC Symbol;Acc:13266]","ENSG00000089737","ENSP00000452145",2,"Helicase_C[1],DEAD[1]","family-272","DDX24",".",".","rRNA","putative rRNA","MAK5 yeast homolog ","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003724,GO:0004004,GO:0016070","RNA binding,RNA helicase activity,ATP-dependent RNA helicase activity,RNA metabolic process","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005737,GO:0005730,GO:0003723,GO:0003724,GO:0004004,GO:0016070","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,cytoplasm,nucleolus,RNA binding,RNA helicase activity,ATP-dependent RNA helicase activity,RNA metabolic process","."]
["RTCB","chromosome 22 open reading frame 28 [Source:HGNC Symbol;Acc:26935]","ENSG00000100220","ENSP00000216038",1,"RtcB[1]","family-273","RTCB",".",".","tRNA","tRNA",21311021,"candidate mRNA binder","novel",1,1,1,".","GO:0006396,GO:0003972,GO:0072669,GO:0006388","RNA processing,RNA ligase (ATP) activity,tRNA-splicing ligase complex,tRNA splicing, via endonucleolytic cleavage and ligation","GO:0008452,GO:0006396,GO:0005524,GO:0046872,GO:0017166,GO:0003972,GO:0005737,GO:0072669,GO:0001890,GO:0007160,GO:0001701,GO:0006388,GO:0034446","RNA ligase activity,RNA processing,ATP binding,metal ion binding,vinculin binding,RNA ligase (ATP) activity,cytoplasm,tRNA-splicing ligase complex,placenta development,cell-matrix adhesion,in utero embryonic development,tRNA splicing, via endonucleolytic cleavage and ligation,substrate adhesion-dependent cell spreading","."]
["MBNL2","muscleblind-like splicing regulator 2 [Source:HGNC Symbol;Acc:16746]","ENSG00000139793","ENSP00000267287",2,"zf-CCCH[2]","family-274","MBNL1,MBNL2,MBNL3","MBNL1","MBNL2[67,71],MBNL3[59,64]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0000381,GO:0043484","RNA binding,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of RNA splicing","GO:0046872,GO:0003723,GO:0005634,GO:0005737,GO:0006397,GO:0008380,GO:0000381,GO:0043484","metal ion binding,RNA binding,nucleus,cytoplasm,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of RNA splicing","."]
["MBNL3","muscleblind-like splicing regulator 3 [Source:HGNC Symbol;Acc:20564]","ENSG00000076770","ENSP00000359890",2,"zf-CCCH[2]","family-274","MBNL1,MBNL2,MBNL3","MBNL1","MBNL2[67,71],MBNL3[59,64]","mRNA","mRNA","established RBP ","RNAbinding","RNArelated",1,1,".",1,"GO:0006397,GO:0008380,GO:0043484","mRNA processing,RNA splicing,regulation of RNA splicing","GO:0046872,GO:0005634,GO:0043231,GO:0005794,GO:0007275,GO:0006397,GO:0008380,GO:0043484,GO:0045662","metal ion binding,nucleus,intracellular membrane-bounded organelle,Golgi apparatus,multicellular organismal development,mRNA processing,RNA splicing,regulation of RNA splicing,negative regulation of myoblast differentiation","."]
["MBNL1","muscleblind-like splicing regulator 1 [Source:HGNC Symbol;Acc:6923]","ENSG00000152601","ENSP00000420327",1,"zf-CCCH[1]","family-274","MBNL1,MBNL2,MBNL3","MBNL1","MBNL2[67,71],MBNL3[59,64]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0003725,GO:0010494,GO:0008380,GO:0000381,GO:0043484,GO:0006376,GO:0000380","RNA binding,double-stranded RNA binding,cytoplasmic stress granule,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of RNA splicing,mRNA splice site selection,alternative mRNA splicing, via spliceosome","GO:0003723,GO:0005515,GO:0046872,GO:0003725,GO:0005634,GO:0005737,GO:0010494,GO:0008380,GO:0000381,GO:0001701,GO:0007399,GO:0043484,GO:0006376,GO:0030326,GO:0045445,GO:0007519,GO:0000380","RNA binding,protein binding,metal ion binding,double-stranded RNA binding,nucleus,cytoplasm,cytoplasmic stress granule,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,in utero embryonic development,nervous system development,regulation of RNA splicing,mRNA splice site selection,embryonic limb morphogenesis,myoblast differentiation,skeletal muscle tissue development,alternative mRNA splicing, via spliceosome"," MYOTONIC DYSTROPHY 1; DM1"]
["ALYREF","Aly/REF export factor [Source:HGNC Symbol;Acc:19071]","ENSG00000183684","ENSP00000421592",3,"FoP_duplication[1],RRM_1[1],FYTT[1]","family-275","ALYREF",".",".","mRNA","mRNA",17190602,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0071013,GO:0008380,GO:0000398,GO:0006406,GO:0031124","RNA binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005829,GO:0005654,GO:0016607,GO:0035145,GO:0071013,GO:0000346,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0031297,GO:0006406,GO:0031124,GO:0019048,GO:0032786,GO:0006369,GO:0000018,GO:0046784","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,cytosol,nucleoplasm,nuclear speck,exon-exon junction complex,catalytic step 2 spliceosome,transcription export complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,replication fork processing,mRNA export from nucleus,mRNA 3'-end processing,modulation by virus of host morphology or physiology,positive regulation of DNA-dependent transcription, elongation,termination of RNA polymerase II transcription,regulation of DNA recombination,viral mRNA export from host cell nucleus","."]
["LSMD1","LSM domain containing 1 [Source:HGNC Symbol;Acc:28212]","ENSG00000183011","ENSP00000335611",1,"LSM[1]","family-276","LSMD1",".",".","mRNA","putative mRNA",19398576,".",".",".",".",".",1,".",".","GO:0005634,GO:0005737","nucleus,cytoplasm","."]
["PUS7","pseudouridylate synthase 7 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26033]","ENSG00000091127","ENSP00000417718",2,"TruD[1],R3H[1]","family-277","PUS7,PUS7L","PUS7","PUS7L[24,23]","rRNA","rRNA/tRNA/snRNA",18332121,"RNAmod","RNAbinding",1,1,1,".","GO:0003723,GO:0009451,GO:0008033","RNA binding,RNA modification,tRNA processing","GO:0003723,GO:0009982,GO:0001522,GO:0009451,GO:0008033","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification,tRNA processing","."]
["PUS7L","pseudouridylate synthase 7 homolog (S. cerevisiae)-like [Source:HGNC Symbol;Acc:25276]","ENSG00000129317","ENSP00000446865",1,"TruD[1]","family-277","PUS7,PUS7L","PUS7","PUS7L[24,23]","rRNA","putative tRNA/rRNA/snRNA","Pseudouridine synthase; catalyzes pseudouridylation at positions 35 and 56 in U2 snRNA, position 50 in 5S rRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); conserved in archaea, vertebrates, and some bacteria ",".",".",".",".",".",".","GO:0003723,GO:0009451,GO:0008033","RNA binding,RNA modification,tRNA processing","GO:0003723,GO:0009982,GO:0001522,GO:0009451,GO:0008033","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification,tRNA processing","."]
["MRPS24","mitochondrial ribosomal protein S24 [Source:HGNC Symbol;Acc:14510]","ENSG00000062582","ENSP00000318158",1,"MRP-S24[1]","family-278","MRPS24",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005762,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrial large ribosomal subunit,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005739,GO:0005762,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrion,mitochondrial large ribosomal subunit,mitochondrial small ribosomal subunit,translation","."]
["RBBP6","retinoblastoma binding protein 6 [Source:HGNC Symbol;Acc:9889]","ENSG00000122257","ENSP00000317872",3,"DWNN[1],zf-CCHC[1],zf-C3HC4_2[1]","family-279","RBBP6",".",".","mRNA","putative mRNA",16396680,"candidate mRNA binder",".",".",1,".",".",".",".","GO:0005515,GO:0008270,GO:0003676,GO:0004842,GO:0005634,GO:0005737,GO:0005694,GO:0005730,GO:0005815,GO:0000151,GO:0016567,GO:0042787,GO:0035264,GO:0001701,GO:0048568,GO:0061053","protein binding,zinc ion binding,nucleic acid binding,ubiquitin-protein ligase activity,nucleus,cytoplasm,chromosome,nucleolus,microtubule organizing center,ubiquitin ligase complex,protein ubiquitination,protein ubiquitination involved in ubiquitin-dependent protein catabolic process,multicellular organism growth,in utero embryonic development,embryonic organ development,somite development","."]
["RPL19","ribosomal protein L19 [Source:HGNC Symbol;Acc:10312]","ENSG00000108298","ENSP00000225430",1,"Ribosomal_L19e[1]","family-28","RPL19",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022625,GO:0003723,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,cytosolic large ribosomal subunit,RNA binding,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0022625,GO:0003723,GO:0005829,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,cytosolic large ribosomal subunit,RNA binding,cytosol,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["NOL3","nucleolar protein 3 (apoptosis repressor with CARD domain) [Source:HGNC Symbol;Acc:7869]","ENSG00000140939","ENSP00000399831",1,"CARD[1]","family-280","NOL3",".",".","mRNA","mRNA",10196175,".",".",".",".",".",".","GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0003723,GO:0005515,GO:0042802,GO:0005739,GO:0005829,GO:0005622,GO:0005730,GO:0016528,GO:0006915,GO:0042981,GO:0043066,GO:0006397,GO:0008380","RNA binding,protein binding,identical protein binding,mitochondrion,cytosol,intracellular,nucleolus,sarcoplasm,apoptotic process,regulation of apoptotic process,negative regulation of apoptotic process,mRNA processing,RNA splicing"," MYOCLONUS, FAMILIAL CORTICAL; FCM"]
["RPS27","ribosomal protein S27 [Source:HGNC Symbol;Acc:10416]","ENSG00000177954","ENSP00000357555",1,"Ribosomal_S27e[1]","family-281","RPS27,RPS27L","RPS27","RPS27L[96,96]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0005515,GO:0008270,GO:0046872,GO:0003677,GO:0005634,GO:0005829,GO:0005622,GO:0022627,GO:0008283,GO:0000278,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,protein binding,zinc ion binding,metal ion binding,DNA binding,nucleus,cytosol,intracellular,cytosolic small ribosomal subunit,cell proliferation,mitotic cell cycle,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS27L","ribosomal protein S27-like [Source:HGNC Symbol;Acc:18476]","ENSG00000185088","ENSP00000412026",1,"Ribosomal_S27e[1]","family-281","RPS27,RPS27L","RPS27","RPS27L[96,96]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0008494,GO:0045727","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,translation activator activity,positive regulation of translation","GO:0046872,GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0022627,GO:0005515,GO:0008656,GO:0008494,GO:0005634,GO:0006974,GO:0006281,GO:0045727,GO:0031571,GO:0042771,GO:0006919","metal ion binding,structural constituent of ribosome,intracellular,ribosome,translation,cytosolic small ribosomal subunit,protein binding,cysteine-type endopeptidase activator activity involved in apoptotic process,translation activator activity,nucleus,cellular response to DNA damage stimulus,DNA repair,positive regulation of translation,mitotic G1 DNA damage checkpoint,intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,activation of cysteine-type endopeptidase activity involved in apoptotic process","."]
["PTRF","polymerase I and transcript release factor [Source:HGNC Symbol;Acc:9688]","ENSG00000177469","ENSP00000349541",1,"PTRF_SDPR[1]","family-282","MURC,PTRF,SDPR,PRKCDBP","MURC","PTRF[29,27],SDPR[29,25],PRKCDBP[15,21]","rRNA","putative rRNA","This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009]",".","RNAbinding",".",1,".",".","GO:0042134","rRNA primary transcript binding","GO:0042134,GO:0005515,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005783,GO:0005654,GO:0005901,GO:0006361,GO:0006363,GO:0006355,GO:0010467,GO:0006360","rRNA primary transcript binding,protein binding,nucleus,cytoplasm,mitochondrion,cytosol,endoplasmic reticulum,nucleoplasm,caveola,transcription initiation from RNA polymerase I promoter,termination of RNA polymerase I transcription,regulation of transcription, DNA-dependent,gene expression,transcription from RNA polymerase I promoter"," LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 4; CGL4"]
["MRPS18A","mitochondrial ribosomal protein S18A [Source:HGNC Symbol;Acc:14515]","ENSG00000096080","ENSP00000361188",1,"Ribosomal_S18[1]","family-283","MRPS18A",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005763","structural constituent of ribosome,ribosome,translation,mitochondrial small ribosomal subunit","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005763,GO:0005739","structural constituent of ribosome,intracellular,ribosome,translation,mitochondrial small ribosomal subunit,mitochondrion","."]
["SLBP","stem-loop binding protein [Source:HGNC Symbol;Acc:10904]","ENSG00000163950","ENSP00000316490",1,"SLBP_RNA_bind[1]","family-284","SLBP",".",".","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,".",1,"GO:0003729,GO:0071207,GO:0071208,GO:0030529,GO:0071204,GO:0006398,GO:0051028,GO:0006406,GO:0031124,GO:0008334","mRNA binding,histone pre-mRNA stem-loop binding,histone pre-mRNA DCP binding,ribonucleoprotein complex,histone pre-mRNA 3'end processing complex,histone mRNA 3'-end processing,mRNA transport,mRNA export from nucleus,mRNA 3'-end processing,histone mRNA metabolic process","GO:0003729,GO:0071207,GO:0005515,GO:0071208,GO:0005737,GO:0005634,GO:0030529,GO:0071204,GO:0005829,GO:0005654,GO:0006398,GO:0006366,GO:0010467,GO:0051028,GO:0006406,GO:0031124,GO:0006369,GO:0008334,GO:0033260","mRNA binding,histone pre-mRNA stem-loop binding,protein binding,histone pre-mRNA DCP binding,cytoplasm,nucleus,ribonucleoprotein complex,histone pre-mRNA 3'end processing complex,cytosol,nucleoplasm,histone mRNA 3'-end processing,transcription from RNA polymerase II promoter,gene expression,mRNA transport,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription,histone mRNA metabolic process,nuclear cell cycle DNA replication","."]
["EARS2","glutamyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:29419]","ENSG00000103356","ENSP00000456467",1,"tRNA-synt_1c[1]","family-285","EARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000049,GO:0016876,GO:0004818,GO:0050561,GO:0006418,GO:0043039,GO:0006424,GO:0070127","tRNA binding,ligase activity, forming aminoacyl-tRNA and related compounds,glutamate-tRNA ligase activity,glutamate-tRNA(Gln) ligase activity,tRNA aminoacylation for protein translation,tRNA aminoacylation,glutamyl-tRNA aminoacylation,tRNA aminoacylation for mitochondrial protein translation","GO:0000166,GO:0005524,GO:0000049,GO:0016876,GO:0004818,GO:0050561,GO:0005739,GO:0005737,GO:0005759,GO:0010467,GO:0006418,GO:0043039,GO:0006424,GO:0070127","nucleotide binding,ATP binding,tRNA binding,ligase activity, forming aminoacyl-tRNA and related compounds,glutamate-tRNA ligase activity,glutamate-tRNA(Gln) ligase activity,mitochondrion,cytoplasm,mitochondrial matrix,gene expression,tRNA aminoacylation for protein translation,tRNA aminoacylation,glutamyl-tRNA aminoacylation,tRNA aminoacylation for mitochondrial protein translation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 12; COXPD12"]
["SMAD1","SMAD family member 1 [Source:HGNC Symbol;Acc:6767]","ENSG00000170365","ENSP00000426568",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","miRNA",20705240,".",".",".",".",".",".","GO:0031053","primary miRNA processing","GO:0005515,GO:0003700,GO:0046872,GO:0019901,GO:0042802,GO:0000979,GO:0070410,GO:0005057,GO:0070411,GO:0030618,GO:0016021,GO:0005634,GO:0005667,GO:0005737,GO:0005829,GO:0005622,GO:0005654,GO:0005637,GO:0006357,GO:0045944,GO:0010628,GO:0010656,GO:0045597,GO:0006351,GO:0008285,GO:0006954,GO:0060348,GO:0006355,GO:0007165,GO:0042493,GO:0006468,GO:0009880,GO:0007179,GO:0042060,GO:0030902,GO:0071407,GO:0051216,GO:0030509,GO:0060038,GO:0001822,GO:0045669,GO:0010243,GO:0050775,GO:0001657,GO:0030901,GO:0007276,GO:0000165,GO:0002051,GO:0071773,GO:1901522,GO:0001710,GO:0042592,GO:0061036,GO:0007183,GO:0031053","protein binding,sequence-specific DNA binding transcription factor activity,metal ion binding,protein kinase binding,identical protein binding,RNA polymerase II core promoter sequence-specific DNA binding,co-SMAD binding,receptor signaling protein activity,I-SMAD binding,transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,integral to membrane,nucleus,transcription factor complex,cytoplasm,cytosol,intracellular,nucleoplasm,nuclear inner membrane,regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,positive regulation of gene expression,negative regulation of muscle cell apoptotic process,positive regulation of cell differentiation,transcription, DNA-templated,negative regulation of cell proliferation,inflammatory response,bone development,regulation of transcription, DNA-dependent,signal transduction,response to drug,protein phosphorylation,embryonic pattern specification,transforming growth factor beta receptor signaling pathway,wound healing,hindbrain development,cellular response to organic cyclic compound,cartilage development,BMP signaling pathway,cardiac muscle cell proliferation,kidney development,positive regulation of osteoblast differentiation,response to organonitrogen compound,positive regulation of dendrite morphogenesis,ureteric bud development,midbrain development,gamete generation,MAPK cascade,osteoblast fate commitment,cellular response to BMP stimulus,positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus,mesodermal cell fate commitment,homeostatic process,positive regulation of cartilage development,SMAD protein complex assembly,primary miRNA processing","."]
["SMAD2","SMAD family member 2 [Source:HGNC Symbol;Acc:6768]","ENSG00000175387","ENSP00000384449",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".","GO:0031053","primary miRNA processing","GO:0003700,GO:0005515,GO:0046872,GO:0003677,GO:0003690,GO:0031625,GO:0003682,GO:0008134,GO:0019902,GO:0070410,GO:0070412,GO:0033613,GO:0046332,GO:0005160,GO:0070411,GO:0034713,GO:0030618,GO:0005634,GO:0005667,GO:0005737,GO:0005829,GO:0005622,GO:0005654,GO:0032444,GO:0071141,GO:0000122,GO:0006351,GO:0045944,GO:0008285,GO:0045893,GO:0045892,GO:0006355,GO:0035556,GO:0010467,GO:0060039,GO:0009791,GO:0001701,GO:0006367,GO:0035265,GO:0048589,GO:0045165,GO:0007179,GO:0030512,GO:0009749,GO:0009952,GO:0001707,GO:0001706,GO:0030513,GO:0048617,GO:0048701,GO:0031016,GO:0007369,GO:0060021,GO:0070723,GO:0001657,GO:0030324,GO:0030073,GO:0032924,GO:0017015,GO:0038092,GO:0007182,GO:0007183,GO:0048340,GO:0051098,GO:0010718,GO:0007352,GO:0031053,GO:1900224,GO:0006468,GO:0009880,GO:0043234,GO:0007492,GO:0007507,GO:0007389,GO:0023019","sequence-specific DNA binding transcription factor activity,protein binding,metal ion binding,DNA binding,double-stranded DNA binding,ubiquitin protein ligase binding,chromatin binding,transcription factor binding,phosphatase binding,co-SMAD binding,R-SMAD binding,activating transcription factor binding,SMAD binding,transforming growth factor beta receptor binding,I-SMAD binding,type I transforming growth factor beta receptor binding,transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,nucleus,transcription factor complex,cytoplasm,cytosol,intracellular,nucleoplasm,activin responsive factor complex,SMAD protein complex,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,negative regulation of cell proliferation,positive regulation of transcription, DNA-dependent,negative regulation of transcription, DNA-dependent,regulation of transcription, DNA-dependent,intracellular signal transduction,gene expression,pericardium development,post-embryonic development,in utero embryonic development,transcription initiation from RNA polymerase II promoter,organ growth,developmental growth,cell fate commitment,transforming growth factor beta receptor signaling pathway,negative regulation of transforming growth factor beta receptor signaling pathway,response to glucose,anterior/posterior pattern specification,mesoderm formation,endoderm formation,positive regulation of BMP signaling pathway,embryonic foregut morphogenesis,embryonic cranial skeleton morphogenesis,pancreas development,gastrulation,palate development,response to cholesterol,ureteric bud development,lung development,insulin secretion,activin receptor signaling pathway,regulation of transforming growth factor beta receptor signaling pathway,nodal signaling pathway,common-partner SMAD protein phosphorylation,SMAD protein complex assembly,paraxial mesoderm morphogenesis,regulation of binding,positive regulation of epithelial to mesenchymal transition,zygotic specification of dorsal/ventral axis,primary miRNA processing,positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry,protein phosphorylation,embryonic pattern specification,protein complex,endoderm development,heart development,pattern specification process,signal transduction involved in regulation of gene expression","."]
["SMAD5","SMAD family member 5 [Source:HGNC Symbol;Acc:6771]","ENSG00000113658","ENSP00000441954",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".",".",".","GO:0003700,GO:0005515,GO:0046872,GO:0031625,GO:0000979,GO:0005057,GO:0030618,GO:0016021,GO:0005634,GO:0005667,GO:0005737,GO:0005829,GO:0005622,GO:0005654,GO:0006351,GO:0045893,GO:0060348,GO:0006355,GO:0007165,GO:0006468,GO:0009880,GO:0007179,GO:0071407,GO:0007281,GO:0030218,GO:0051216,GO:0030509,GO:0045669,GO:0001657,GO:0001880,GO:0002051,GO:0060048,GO:0071773,GO:1901522,GO:0045944,GO:0001503","sequence-specific DNA binding transcription factor activity,protein binding,metal ion binding,ubiquitin protein ligase binding,RNA polymerase II core promoter sequence-specific DNA binding,receptor signaling protein activity,transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,integral to membrane,nucleus,transcription factor complex,cytoplasm,cytosol,intracellular,nucleoplasm,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,bone development,regulation of transcription, DNA-dependent,signal transduction,protein phosphorylation,embryonic pattern specification,transforming growth factor beta receptor signaling pathway,cellular response to organic cyclic compound,germ cell development,erythrocyte differentiation,cartilage development,BMP signaling pathway,positive regulation of osteoblast differentiation,ureteric bud development,Mullerian duct regression,osteoblast fate commitment,cardiac muscle contraction,cellular response to BMP stimulus,positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus,positive regulation of transcription from RNA polymerase II promoter,ossification","."]
["SMAD9","SMAD family member 9 [Source:HGNC Symbol;Acc:6774]","ENSG00000120693","ENSP00000369154",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".",".",".","GO:0005515,GO:0003700,GO:0046872,GO:0003677,GO:0030618,GO:0005737,GO:0005634,GO:0005667,GO:0005829,GO:0005622,GO:0005654,GO:0030509,GO:0006351,GO:0045893,GO:0060348,GO:0006355,GO:0001666,GO:0006468,GO:0007179,GO:0030902,GO:0071407,GO:0051216,GO:0001657,GO:0030901,GO:0001880,GO:0045597","protein binding,sequence-specific DNA binding transcription factor activity,metal ion binding,DNA binding,transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,cytoplasm,nucleus,transcription factor complex,cytosol,intracellular,nucleoplasm,BMP signaling pathway,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,bone development,regulation of transcription, DNA-dependent,response to hypoxia,protein phosphorylation,transforming growth factor beta receptor signaling pathway,hindbrain development,cellular response to organic cyclic compound,cartilage development,ureteric bud development,midbrain development,Mullerian duct regression,positive regulation of cell differentiation"," PULMONARY HYPERTENSION, PRIMARY, 2; PPH2"]
["SMAD3","SMAD family member 3 [Source:HGNC Symbol;Acc:6769]","ENSG00000166949","ENSP00000332973",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".","GO:0031053","primary miRNA processing","GO:0005515,GO:0005622,GO:0006355,GO:0003700,GO:0003690,GO:0005518,GO:0043565,GO:0008134,GO:0031490,GO:0046332,GO:0005634,GO:0005886,GO:0005667,GO:0005737,GO:0000122,GO:0045944,GO:0050776,GO:0043066,GO:0060039,GO:0001701,GO:0009880,GO:0001756,GO:0050728,GO:0001889,GO:0048589,GO:0042110,GO:0007179,GO:0030335,GO:0051496,GO:0001707,GO:0048617,GO:0001836,GO:0048701,GO:0051894,GO:0061045,GO:0001657,GO:0030878,GO:0002076,GO:0045668,GO:0032731,GO:0070306,GO:0032332,GO:0030501,GO:0050678,GO:0010694,GO:0007492,GO:0001947,GO:0017015,GO:0033689,GO:0002520,GO:0007183,GO:0016202,GO:0032916,GO:0048340,GO:0050927,GO:0051098,GO:0060290,GO:0042803,GO:0008270,GO:0031625,GO:0019901,GO:0043130,GO:0019902,GO:0070410,GO:0070412,GO:0044212,GO:0008013,GO:0000988,GO:0000987,GO:0005160,GO:0001102,GO:0030618,GO:0005829,GO:0005654,GO:0005637,GO:0043235,GO:0071141,GO:0006351,GO:0045893,GO:0030308,GO:0001933,GO:0006955,GO:0001666,GO:0006810,GO:0010467,GO:0007050,GO:0006367,GO:0042060,GO:0030512,GO:0090263,GO:0045930,GO:0050821,GO:0042177,GO:0045216,GO:0006919,GO:0032924,GO:0038092,GO:0010718,GO:0097191,GO:0035413,GO:0042993,GO:0019049,GO:0032909,GO:0031053,GO:1901313,GO:0003682,GO:0019899,GO:0003677,GO:0043234,GO:0001501,GO:0001649,GO:0007369,GO:0023019,GO:0008285,GO:0097296","protein binding,intracellular,regulation of transcription, DNA-dependent,sequence-specific DNA binding transcription factor activity,double-stranded DNA binding,collagen binding,sequence-specific DNA binding,transcription factor binding,chromatin DNA binding,SMAD binding,nucleus,plasma membrane,transcription factor complex,cytoplasm,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,regulation of immune response,negative regulation of apoptotic process,pericardium development,in utero embryonic development,embryonic pattern specification,somitogenesis,negative regulation of inflammatory response,liver development,developmental growth,T cell activation,transforming growth factor beta receptor signaling pathway,positive regulation of cell migration,positive regulation of stress fiber assembly,mesoderm formation,embryonic foregut morphogenesis,release of cytochrome c from mitochondria,embryonic cranial skeleton morphogenesis,positive regulation of focal adhesion assembly,negative regulation of wound healing,ureteric bud development,thyroid gland development,osteoblast development,negative regulation of osteoblast differentiation,positive regulation of interleukin-1 beta production,lens fiber cell differentiation,positive regulation of chondrocyte differentiation,positive regulation of bone mineralization,regulation of epithelial cell proliferation,positive regulation of alkaline phosphatase activity,endoderm development,heart looping,regulation of transforming growth factor beta receptor signaling pathway,negative regulation of osteoblast proliferation,immune system development,SMAD protein complex assembly,regulation of striated muscle tissue development,positive regulation of transforming growth factor beta3 production,paraxial mesoderm morphogenesis,positive regulation of positive chemotaxis,regulation of binding,transdifferentiation,protein homodimerization activity,zinc ion binding,ubiquitin protein ligase binding,protein kinase binding,ubiquitin binding,phosphatase binding,co-SMAD binding,R-SMAD binding,transcription regulatory region DNA binding,beta-catenin binding,protein binding transcription factor activity,core promoter proximal region sequence-specific DNA binding,transforming growth factor beta receptor binding,RNA polymerase II activating transcription factor binding,transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity,cytosol,nucleoplasm,nuclear inner membrane,receptor complex,SMAD protein complex,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,negative regulation of cell growth,negative regulation of protein phosphorylation,immune response,response to hypoxia,transport,gene expression,cell cycle arrest,transcription initiation from RNA polymerase II promoter,wound healing,negative regulation of transforming growth factor beta receptor signaling pathway,positive regulation of canonical Wnt signaling pathway,negative regulation of mitotic cell cycle,protein stabilization,negative regulation of protein catabolic process,cell-cell junction organization,activation of cysteine-type endopeptidase activity involved in apoptotic process,activin receptor signaling pathway,nodal signaling pathway,positive regulation of epithelial to mesenchymal transition,extrinsic apoptotic signaling pathway,positive regulation of catenin import into nucleus,positive regulation of transcription factor import into nucleus,evasion or tolerance of host defenses by virus,regulation of transforming growth factor beta2 production,primary miRNA processing,positive regulation of gene expression involved in extracellular matrix organization,chromatin binding,enzyme binding,DNA binding,protein complex,skeletal system development,osteoblast differentiation,gastrulation,signal transduction involved in regulation of gene expression,negative regulation of cell proliferation,activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway"," COLORECTAL CANCER; CRC"]
["SMAD4","SMAD family member 4 [Source:HGNC Symbol;Acc:6770]","ENSG00000141646","ENSP00000341551",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".",".",".","GO:0003700,GO:0003677,GO:0005518,GO:0003682,GO:0001085,GO:0001076,GO:0005634,GO:0005667,GO:0005737,GO:0005622,GO:0006351,GO:0008283,GO:0045944,GO:0007411,GO:0008285,GO:0006355,GO:0001701,GO:0048589,GO:0001658,GO:0007179,GO:0060548,GO:0001702,GO:0048733,GO:0007498,GO:0048663,GO:0060021,GO:0003360,GO:0003198,GO:0036302,GO:0007492,GO:0014033,GO:0010862,GO:0032525,GO:0051098,GO:0003190,GO:0003251,GO:0003279,GO:0010718,GO:0042118,GO:0048859,GO:0051797,GO:0060391,GO:0060956,GO:0072133,GO:0072134,GO:0005515,GO:0042803,GO:0046872,GO:0043565,GO:0042802,GO:0070412,GO:0044212,GO:0000988,GO:0000987,GO:0070411,GO:0030616,GO:0005829,GO:0005654,GO:0005813,GO:0032444,GO:0071141,GO:0006357,GO:0009952,GO:0045893,GO:0042127,GO:0006366,GO:0001822,GO:0007369,GO:0048729,GO:0000122,GO:0030308,GO:0045892,GO:0001666,GO:0010467,GO:0006367,GO:0030509,GO:0030513,GO:0060395,GO:0071559,GO:0042177,GO:0030511,GO:0017015,GO:0007183,GO:0032909","sequence-specific DNA binding transcription factor activity,DNA binding,collagen binding,chromatin binding,RNA polymerase II transcription factor binding,RNA polymerase II transcription factor binding transcription factor activity,nucleus,transcription factor complex,cytoplasm,intracellular,transcription, DNA-templated,cell proliferation,positive regulation of transcription from RNA polymerase II promoter,axon guidance,negative regulation of cell proliferation,regulation of transcription, DNA-dependent,in utero embryonic development,developmental growth,branching involved in ureteric bud morphogenesis,transforming growth factor beta receptor signaling pathway,negative regulation of cell death,gastrulation with mouth forming second,sebaceous gland development,mesoderm development,neuron fate commitment,palate development,brainstem development,epithelial to mesenchymal transition involved in endocardial cushion formation,atrioventricular canal development,endoderm development,neural crest cell differentiation,positive regulation of pathway-restricted SMAD protein phosphorylation,somite rostral/caudal axis specification,regulation of binding,atrioventricular valve formation,positive regulation of cell proliferation involved in heart valve morphogenesis,cardiac septum development,positive regulation of epithelial to mesenchymal transition,endothelial cell activation,formation of anatomical boundary,regulation of hair follicle development,positive regulation of SMAD protein import into nucleus,endocardial cell differentiation,metanephric mesenchyme morphogenesis,nephrogenic mesenchyme morphogenesis,protein binding,protein homodimerization activity,metal ion binding,sequence-specific DNA binding,identical protein binding,R-SMAD binding,transcription regulatory region DNA binding,protein binding transcription factor activity,core promoter proximal region sequence-specific DNA binding,I-SMAD binding,transforming growth factor beta receptor, common-partner cytoplasmic mediator activity,cytosol,nucleoplasm,centrosome,activin responsive factor complex,SMAD protein complex,regulation of transcription from RNA polymerase II promoter,anterior/posterior pattern specification,positive regulation of transcription, DNA-dependent,regulation of cell proliferation,transcription from RNA polymerase II promoter,kidney development,gastrulation,tissue morphogenesis,negative regulation of transcription from RNA polymerase II promoter,negative regulation of cell growth,negative regulation of transcription, DNA-dependent,response to hypoxia,gene expression,transcription initiation from RNA polymerase II promoter,BMP signaling pathway,positive regulation of BMP signaling pathway,SMAD protein signal transduction,response to transforming growth factor beta,negative regulation of protein catabolic process,positive regulation of transforming growth factor beta receptor signaling pathway,regulation of transforming growth factor beta receptor signaling pathway,SMAD protein complex assembly,regulation of transforming growth factor beta2 production"," COLORECTAL CANCER; CRC"]
["SMAD7","MAD family member 7 [Source:HGNC Symbol;Acc:6773]","ENSG00000101665","ENSP00000262158",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".",".",".","GO:0005515,GO:0005518,GO:0031625,GO:0005634,GO:0005622,GO:0043234,GO:0045892,GO:0006355,GO:0035556,GO:0007179,GO:0030514,GO:0055010,GO:0048844,GO:0001657,GO:0060412,GO:0055117,GO:0060389,GO:0017015,GO:0003700,GO:0046872,GO:0044212,GO:0048185,GO:0008013,GO:0070411,GO:0030617,GO:0034713,GO:0005886,GO:0005667,GO:0005737,GO:0005829,GO:0005654,GO:0005913,GO:0016342,GO:0000122,GO:0006351,GO:0045944,GO:0043433,GO:0010467,GO:0006367,GO:0031398,GO:0030336,GO:0030512,GO:0032436,GO:0034616,GO:0030509,GO:0034629,GO:0033137,GO:0050821,GO:0010801,GO:0022409,GO:0031397,GO:0032925,GO:0051444,GO:0010719,GO:0010944,GO:0034333,GO:0060373,GO:0060394","protein binding,collagen binding,ubiquitin protein ligase binding,nucleus,intracellular,protein complex,negative regulation of transcription, DNA-dependent,regulation of transcription, DNA-dependent,intracellular signal transduction,transforming growth factor beta receptor signaling pathway,negative regulation of BMP signaling pathway,ventricular cardiac muscle tissue morphogenesis,artery morphogenesis,ureteric bud development,ventricular septum morphogenesis,regulation of cardiac muscle contraction,pathway-restricted SMAD protein phosphorylation,regulation of transforming growth factor beta receptor signaling pathway,sequence-specific DNA binding transcription factor activity,metal ion binding,transcription regulatory region DNA binding,activin binding,beta-catenin binding,I-SMAD binding,transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity,type I transforming growth factor beta receptor binding,plasma membrane,transcription factor complex,cytoplasm,cytosol,nucleoplasm,cell-cell adherens junction,catenin complex,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,negative regulation of sequence-specific DNA binding transcription factor activity,gene expression,transcription initiation from RNA polymerase II promoter,positive regulation of protein ubiquitination,negative regulation of cell migration,negative regulation of transforming growth factor beta receptor signaling pathway,positive regulation of proteasomal ubiquitin-dependent protein catabolic process,response to laminar fluid shear stress,BMP signaling pathway,cellular protein complex localization,negative regulation of peptidyl-serine phosphorylation,protein stabilization,negative regulation of peptidyl-threonine phosphorylation,positive regulation of cell-cell adhesion,negative regulation of protein ubiquitination,regulation of activin receptor signaling pathway,negative regulation of ubiquitin-protein ligase activity,negative regulation of epithelial to mesenchymal transition,negative regulation of transcription by competitive promoter binding,adherens junction assembly,regulation of ventricular cardiac muscle cell membrane depolarization,negative regulation of pathway-restricted SMAD protein phosphorylation"," COLORECTAL CANCER, SUSCEPTIBILITY TO, 3; CRCS3"]
["SMAD6","SMAD family member 6 [Source:HGNC Symbol;Acc:6772]","ENSG00000137834","ENSP00000288840",2,"MH2[1],MH1[1]","family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","SMAD1","SMAD7[22,24],SMAD6[25,24],SMAD4[39,33],SMAD5[89,89],SMAD9[81,81],SMAD2[61,61],SMAD3[61,67]","ncRNA","putative miRNA",20705240,".",".",".",".",".",".",".",".","GO:0003700,GO:0005515,GO:0046872,GO:0031625,GO:0003682,GO:0070410,GO:0070412,GO:0044212,GO:0070411,GO:0030617,GO:0034713,GO:0070698,GO:0005634,GO:0005667,GO:0005737,GO:0005829,GO:0005622,GO:0006351,GO:0008285,GO:0043066,GO:0006955,GO:0006355,GO:0007179,GO:0030512,GO:0043627,GO:0034616,GO:0030514,GO:0030509,GO:0031589,GO:0001657,GO:0060394,GO:0007352,GO:0010991","sequence-specific DNA binding transcription factor activity,protein binding,metal ion binding,ubiquitin protein ligase binding,chromatin binding,co-SMAD binding,R-SMAD binding,transcription regulatory region DNA binding,I-SMAD binding,transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity,type I transforming growth factor beta receptor binding,type I activin receptor binding,nucleus,transcription factor complex,cytoplasm,cytosol,intracellular,transcription, DNA-templated,negative regulation of cell proliferation,negative regulation of apoptotic process,immune response,regulation of transcription, DNA-dependent,transforming growth factor beta receptor signaling pathway,negative regulation of transforming growth factor beta receptor signaling pathway,response to estrogen,response to laminar fluid shear stress,negative regulation of BMP signaling pathway,BMP signaling pathway,cell-substrate adhesion,ureteric bud development,negative regulation of pathway-restricted SMAD protein phosphorylation,zygotic specification of dorsal/ventral axis,negative regulation of SMAD protein complex assembly"," AORTIC VALVE DISEASE 2; AOVD2"]
["PRPF39","PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20314]","ENSG00000185246","ENSP00000348010",2,"Suf[1],TPR_16[1]","family-287","PRPF39",".",".","snRNA","putative snRNA /mRNA","U1 snRNP protein involved in splicing; contains multiple tetriatricopeptide repeats",".",".",".",".",".",".","GO:0006397,GO:0008380,GO:0006396","mRNA processing,RNA splicing,RNA processing","GO:0005634,GO:0005622,GO:0006397,GO:0008380,GO:0006396","nucleus,intracellular,mRNA processing,RNA splicing,RNA processing","."]
["SRP68","signal recognition particle 68kDa [Source:HGNC Symbol;Acc:11302]","ENSG00000167881","ENSP00000312066",".",".","family-288","SRP68",".",".","ncRNA","7SL","established RBP ",".","RNAbinding",".",1,".",".","GO:0008312,GO:0005840,GO:0006412","7S RNA binding,ribosome,translation","GO:0008312,GO:0005047,GO:0030942,GO:0005737,GO:0005829,GO:0005783,GO:0005730,GO:0005840,GO:0005786,GO:0006412,GO:0042493,GO:0010467,GO:0044267,GO:0006614","7S RNA binding,signal recognition particle binding,endoplasmic reticulum signal peptide binding,cytoplasm,cytosol,endoplasmic reticulum,nucleolus,ribosome,signal recognition particle, endoplasmic reticulum targeting,translation,response to drug,gene expression,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane","."]
["ADARB2","adenosine deaminase, RNA-specific, B2 [Source:HGNC Symbol;Acc:227]","ENSG00000185736","ENSP00000370713",3,"A_deamin[1],dsrm[2]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","mRNA","putative mRNA",10836796,".","RNAbinding",".",1,".",".","GO:0003723,GO:0006396,GO:0003725,GO:0003727,GO:0006397","RNA binding,RNA processing,double-stranded RNA binding,single-stranded RNA binding,mRNA processing","GO:0003723,GO:0004000,GO:0006396,GO:0046872,GO:0003725,GO:0003727,GO:0005634,GO:0005737,GO:0005739,GO:0006397","RNA binding,adenosine deaminase activity,RNA processing,metal ion binding,double-stranded RNA binding,single-stranded RNA binding,nucleus,cytoplasm,mitochondrion,mRNA processing","."]
["ADAD1","adenosine deaminase domain containing 1 (testis-specific) [Source:HGNC Symbol;Acc:30713]","ENSG00000164113","ENSP00000373376",2,"A_deamin[1],dsrm[1]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","mRNA","putative mRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0003723,GO:0004000,GO:0005634,GO:0007275,GO:0006396,GO:0007286","RNA binding,adenosine deaminase activity,nucleus,multicellular organismal development,RNA processing,spermatid development","."]
["ADAD2","adenosine deaminase domain containing 2 [Source:HGNC Symbol;Acc:30714]","ENSG00000140955","ENSP00000268624",2,"A_deamin[1],dsrm[1]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","mRNA","mRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0003723,GO:0004000,GO:0006396","RNA binding,adenosine deaminase activity,RNA processing","."]
["ADAT1","adenosine deaminase, tRNA-specific 1 [Source:HGNC Symbol;Acc:228]","ENSG00000065457","ENSP00000457501",1,"A_deamin[1]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","tRNA","tRNA","The protein encoded by this gene, tRNA-specific adenosine deaminase 1, is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]",".",".",".",".",".",".","GO:0003723,GO:0006396,GO:0008251,GO:0008033","RNA binding,RNA processing,tRNA-specific adenosine deaminase activity,tRNA processing","GO:0003723,GO:0004000,GO:0006396,GO:0046872,GO:0008251,GO:0008033","RNA binding,adenosine deaminase activity,RNA processing,metal ion binding,tRNA-specific adenosine deaminase activity,tRNA processing","."]
["ADARB1","adenosine deaminase, RNA-specific, B1 [Source:HGNC Symbol;Acc:226]","ENSG00000197381","ENSP00000441897",3,"A_deamin[1],dsrm[2]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","mRNA","mRNA","This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq, Jul 2008]","RNAmod",".",".",1,".",".","GO:0003723,GO:0003725,GO:0003729,GO:0003726,GO:0006397,GO:0006396,GO:0016556","RNA binding,double-stranded RNA binding,mRNA binding,double-stranded RNA adenosine deaminase activity,mRNA processing,RNA processing,mRNA modification","GO:0003723,GO:0005515,GO:0046872,GO:0003725,GO:0003729,GO:0003726,GO:0004000,GO:0005634,GO:0005730,GO:0005654,GO:0045087,GO:0008285,GO:0010467,GO:0006397,GO:0006396,GO:0051726,GO:0030336,GO:0051607,GO:0006382,GO:0045070,GO:0044387,GO:0016556,GO:0016553","RNA binding,protein binding,metal ion binding,double-stranded RNA binding,mRNA binding,double-stranded RNA adenosine deaminase activity,adenosine deaminase activity,nucleus,nucleolus,nucleoplasm,innate immune response,negative regulation of cell proliferation,gene expression,mRNA processing,RNA processing,regulation of cell cycle,negative regulation of cell migration,defense response to virus,adenosine to inosine editing,positive regulation of viral genome replication,negative regulation of protein kinase activity by regulation of protein phosphorylation,mRNA modification,base conversion or substitution editing","."]
["ADAR","adenosine deaminase, RNA-specific [Source:HGNC Symbol;Acc:225]","ENSG00000160710","ENSP00000357459",6,"A_deamin[1],z-alpha[2],dsrm[3]","family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","ADAD1","ADAD2[28,24],ADAR[24,11],ADAT1[18,21],ADARB1[25,19],ADARB2[24,19]","mRNA","mRNA","This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]","RNAmod","experimentally validated",1,1,".",".","GO:0003723,GO:0003726,GO:0006396,GO:0044530,GO:0031047,GO:0006397,GO:0016556","RNA binding,double-stranded RNA adenosine deaminase activity,RNA processing,supraspliceosomal complex,gene silencing by RNA,mRNA processing,mRNA modification","GO:0003723,GO:0003726,GO:0004000,GO:0005634,GO:0006396,GO:0005515,GO:0046872,GO:0003677,GO:0005737,GO:0005730,GO:0005654,GO:0044530,GO:0045087,GO:0043066,GO:0009615,GO:0006611,GO:0010467,GO:0031047,GO:0006397,GO:0006606,GO:0019221,GO:0051607,GO:0006382,GO:0045070,GO:0060337,GO:0044387,GO:0035455,GO:0016556,GO:0016553","RNA binding,double-stranded RNA adenosine deaminase activity,adenosine deaminase activity,nucleus,RNA processing,protein binding,metal ion binding,DNA binding,cytoplasm,nucleolus,nucleoplasm,supraspliceosomal complex,innate immune response,negative regulation of apoptotic process,response to virus,protein export from nucleus,gene expression,gene silencing by RNA,mRNA processing,protein import into nucleus,cytokine-mediated signaling pathway,defense response to virus,adenosine to inosine editing,positive regulation of viral genome replication,type I interferon signaling pathway,negative regulation of protein kinase activity by regulation of protein phosphorylation,response to interferon-alpha,mRNA modification,base conversion or substitution editing"," DYSCHROMATOSIS SYMMETRICA HEREDITARIA; DSH"]
["CLK3","CDC-like kinase 3 [Source:HGNC Symbol;Acc:2071]","ENSG00000179335","ENSP00000344112",1,"Pkinase[1]","family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","CLK1","CLK4[72,79],CLK2[50,53],CLK3[46,38],PRPF4B[27,14]","mRNA","mRNA",9637771,"candidate mRNA binder","novel",1,1,".",".","GO:0043484","regulation of RNA splicing","GO:0005515,GO:0005524,GO:0004674,GO:0004713,GO:0004712,GO:0005634,GO:0045111,GO:0001669,GO:0016607,GO:0006468,GO:0043484,GO:0046777,GO:0004672,GO:0016772,GO:0016301,GO:0018108","protein binding,ATP binding,protein serine/threonine kinase activity,protein tyrosine kinase activity,protein serine/threonine/tyrosine kinase activity,nucleus,intermediate filament cytoskeleton,acrosomal vesicle,nuclear speck,protein phosphorylation,regulation of RNA splicing,protein autophosphorylation,protein kinase activity,transferase activity, transferring phosphorus-containing groups,kinase activity,peptidyl-tyrosine phosphorylation","."]
["CLK4","CDC-like kinase 4 [Source:HGNC Symbol;Acc:13659]","ENSG00000113240","ENSP00000316948",1,"Pkinase[1]","family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","CLK1","CLK4[72,79],CLK2[50,53],CLK3[46,38],PRPF4B[27,14]","mRNA","putative mRNA",19168442,".",".",".",".",".",".","GO:0043484","regulation of RNA splicing","GO:0004674,GO:0004713,GO:0005634,GO:0046777,GO:0005524,GO:0004672,GO:0016772,GO:0004712,GO:0018108,GO:0006468,GO:0043484","protein serine/threonine kinase activity,protein tyrosine kinase activity,nucleus,protein autophosphorylation,ATP binding,protein kinase activity,transferase activity, transferring phosphorus-containing groups,protein serine/threonine/tyrosine kinase activity,peptidyl-tyrosine phosphorylation,protein phosphorylation,regulation of RNA splicing","."]
["PRPF4B","PRP4 pre-mRNA processing factor 4 homolog B (yeast) [Source:HGNC Symbol;Acc:17346]","ENSG00000112739","ENSP00000337194",1,"Pkinase[1]","family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","CLK1","CLK4[72,79],CLK2[50,53],CLK3[46,38],PRPF4B[27,14]","snRNA","putative snRNA /mRNA","Splicing factor; component of the U4/U6-U5 snRNP complex","RNAbinding",".",".",1,".",".","GO:0071013,GO:0008380,GO:0000398","catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome","GO:0005524,GO:0004674,GO:0004672,GO:0004713,GO:0016772,GO:0005634,GO:0005694,GO:0006468,GO:0005515,GO:0071013,GO:0008380,GO:0000398","ATP binding,protein serine/threonine kinase activity,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,nucleus,chromosome,protein phosphorylation,protein binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome","."]
["CLK1","CDC-like kinase 1 [Source:HGNC Symbol;Acc:2068]","ENSG00000013441","ENSP00000326830",1,"Pkinase[1]","family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","CLK1","CLK4[72,79],CLK2[50,53],CLK3[46,38],PRPF4B[27,14]","mRNA","mRNA","This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]",".",".",".",".",".",".","GO:0043484","regulation of RNA splicing","GO:0004674,GO:0005515,GO:0005524,GO:0004672,GO:0004713,GO:0016772,GO:0004715,GO:0004712,GO:0005634,GO:0005737,GO:0018108,GO:0008283,GO:0006468,GO:0043484,GO:0018107,GO:0018105,GO:0046777","protein serine/threonine kinase activity,protein binding,ATP binding,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,non-membrane spanning protein tyrosine kinase activity,protein serine/threonine/tyrosine kinase activity,nucleus,cytoplasm,peptidyl-tyrosine phosphorylation,cell proliferation,protein phosphorylation,regulation of RNA splicing,peptidyl-threonine phosphorylation,peptidyl-serine phosphorylation,protein autophosphorylation","."]
["CLK2","CDC-like kinase 2 [Source:HGNC Symbol;Acc:2069]","ENSG00000176444","ENSP00000354856",1,"Pkinase[1]","family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","CLK1","CLK4[72,79],CLK2[50,53],CLK3[46,38],PRPF4B[27,14]","mRNA","putative mRNA","This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. ",".",".",".",".",".",".","GO:0043484","regulation of RNA splicing","GO:0005515,GO:0005524,GO:0004674,GO:0004672,GO:0004713,GO:0016772,GO:0004712,GO:0005634,GO:0016607,GO:0006468,GO:0043484,GO:0046777,GO:0010212,GO:0045721,GO:0032526,GO:0018108,GO:0010033","protein binding,ATP binding,protein serine/threonine kinase activity,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,protein serine/threonine/tyrosine kinase activity,nucleus,nuclear speck,protein phosphorylation,regulation of RNA splicing,protein autophosphorylation,response to ionizing radiation,negative regulation of gluconeogenesis,response to retinoic acid,peptidyl-tyrosine phosphorylation,response to organic substance","."]
["LSM3","LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:17874]","ENSG00000170860","ENSP00000302160",1,"LSM[1]","family-290","LSM3",".",".","snRNA","snRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0071013,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0000398,GO:0043928","RNA binding,catalytic step 2 spliceosome,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0005634,GO:0005829,GO:0071013,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0000398,GO:0043928","RNA binding,protein binding,nucleus,cytosol,catalytic step 2 spliceosome,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["FAM46A","family with sequence similarity 46, member A [Source:HGNC Symbol;Acc:18345]","ENSG00000112773","ENSP00000358769",1,"DUF1693[1]","family-291","FAM46A,FAM46B,FAM46D,FAM46C","FAM46A","FAM46B[58,61],FAM46D[52,59],FAM46C[63,71]","unknown","unknown",19833706,".","novel",".",1,".",".",".",".",".",".","."]
["CRYZ","crystallin, zeta (quinone reductase) [Source:HGNC Symbol;Acc:2419]","ENSG00000116791","ENSP00000399805",2,"ADH_N[1],ADH_zinc_N[1]","family-292","CRYZ,VAT1L,TP53I3,VAT1,ZADH2","CRYZ","VAT1L[31,25],TP53I3[27,27],VAT1[31,26],ZADH2[24,21]","mRNA","mRNA",20103721,".",".",".",".",".",".","GO:0003730","mRNA 3'-UTR binding","GO:0008270,GO:0016491,GO:0016747,GO:0003730,GO:0070402,GO:0003960,GO:0005737,GO:0005829,GO:0043231,GO:0005794,GO:0055114,GO:0007601,GO:0051289,GO:0042178","zinc ion binding,oxidoreductase activity,transferase activity, transferring acyl groups other than amino-acyl groups,mRNA 3'-UTR binding,NADPH binding,NADPH:quinone reductase activity,cytoplasm,cytosol,intracellular membrane-bounded organelle,Golgi apparatus,oxidation-reduction process,visual perception,protein homotetramerization,xenobiotic catabolic process","."]
["KIN","KIN, antigenic determinant of recA protein homolog (mouse) [Source:HGNC Symbol;Acc:6327]","ENSG00000151657","ENSP00000368881",1,"Kin17_mid[1]","family-293","KIN",".",".","snRNA","putative snRNA","12411573 , 17045609",".",".",".",".",".",1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0003690,GO:0003723,GO:0046872,GO:0003677,GO:0005634,GO:0005737,GO:0016363,GO:0006260,GO:0006974,GO:0006281,GO:0006310,GO:0006397,GO:0019048","double-stranded DNA binding,RNA binding,metal ion binding,DNA binding,nucleus,cytoplasm,nuclear matrix,DNA replication,cellular response to DNA damage stimulus,DNA repair,DNA recombination,mRNA processing,modulation by virus of host morphology or physiology","."]
["RPS2","ribosomal protein S2 [Source:HGNC Symbol;Acc:10404]","ENSG00000140988","ENSP00000433034",2,"Ribosomal_S5[1],Ribosomal_S5_C[1]","family-294","RPS2",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0015935,GO:0003729,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,small ribosomal subunit,mRNA binding,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0015935,GO:0005515,GO:0019899,GO:0003729,GO:0017134,GO:0005829,GO:0022627,GO:0005654,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0051347,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,small ribosomal subunit,protein binding,enzyme binding,mRNA binding,fibroblast growth factor binding,cytosol,cytosolic small ribosomal subunit,nucleoplasm,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,positive regulation of transferase activity,translational termination,viral transcription","."]
["DUS4L","dihydrouridine synthase 4-like (S. cerevisiae) [Source:HGNC Symbol;Acc:21517]","ENSG00000105865","ENSP00000265720",1,"Dus[1]","family-295","DUS4L",".",".","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0017150,GO:0008033","tRNA dihydrouridine synthase activity,tRNA processing","GO:0016491,GO:0050660,GO:0010181,GO:0017150,GO:0055114,GO:0008033,GO:0000105","oxidoreductase activity,flavin adenine dinucleotide binding,FMN binding,tRNA dihydrouridine synthase activity,oxidation-reduction process,tRNA processing,histidine biosynthetic process","."]
["EIF4A1","eukaryotic translation initiation factor 4A1 [Source:HGNC Symbol;Acc:3282]","ENSG00000161960","ENSP00000463486",2,"Helicase_C[1],DEAD[1]","family-296","EIF4A1,EIF4A2,EIF4A3","EIF4A1","EIF4A2[90,90],EIF4A3[66,65]","mRNA","mRNA","established RBP ","translationfactor","RNAbinding",1,1,1,".","GO:0003743,GO:0003725,GO:0003729,GO:0000339,GO:0008135,GO:0016281,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006413","translation initiation factor activity,double-stranded RNA binding,mRNA binding,RNA cap binding,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 4F complex,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,translational initiation","GO:0005524,GO:0003676,GO:0008026,GO:0003743,GO:0004386,GO:0005515,GO:0003725,GO:0003729,GO:0000339,GO:0008135,GO:0005829,GO:0016281,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0019221,GO:0044267,GO:0019048,GO:0006413,GO:0003677,GO:0016787,GO:0031100","ATP binding,nucleic acid binding,ATP-dependent helicase activity,translation initiation factor activity,helicase activity,protein binding,double-stranded RNA binding,mRNA binding,RNA cap binding,translation factor activity, nucleic acid binding,cytosol,eukaryotic translation initiation factor 4F complex,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,cytokine-mediated signaling pathway,cellular protein metabolic process,modulation by virus of host morphology or physiology,translational initiation,DNA binding,hydrolase activity,organ regeneration","."]
["EIF4A2","eukaryotic translation initiation factor 4A2 [Source:HGNC Symbol;Acc:3284]","ENSG00000156976","ENSP00000398370",2,"Helicase_C[1],DEAD[1]","family-296","EIF4A1,EIF4A2,EIF4A3","EIF4A1","EIF4A2[90,90],EIF4A3[66,65]","mRNA","mRNA","established RBP ","translationfactor","RNAbinding",1,1,".",".","GO:0003743,GO:0016281,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 4F complex,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translational initiation,translational initiation","GO:0005524,GO:0003676,GO:0008026,GO:0003743,GO:0004386,GO:0003677,GO:0016787,GO:0005829,GO:0016281,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0019221,GO:0006446,GO:0044267,GO:0019048,GO:0006413","ATP binding,nucleic acid binding,ATP-dependent helicase activity,translation initiation factor activity,helicase activity,DNA binding,hydrolase activity,cytosol,eukaryotic translation initiation factor 4F complex,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,cytokine-mediated signaling pathway,regulation of translational initiation,cellular protein metabolic process,modulation by virus of host morphology or physiology,translational initiation","."]
["EIF4A3","eukaryotic translation initiation factor 4A3 [Source:HGNC Symbol;Acc:18683]","ENSG00000141543","ENSP00000269349",2,"Helicase_C[1],DEAD[1]","family-296","EIF4A1,EIF4A2,EIF4A3","EIF4A1","EIF4A2[90,90],EIF4A3[66,65]","mRNA","mRNA","established RBP ","translationfactor","experimentally validated",1,1,1,".","GO:0003729,GO:0008143,GO:0004004,GO:0071013,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0051028,GO:0000398,GO:0006364,GO:0045727,GO:0000184","mRNA binding,poly(A) RNA binding,ATP-dependent RNA helicase activity,catalytic step 2 spliceosome,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,mRNA transport,mRNA splicing, via spliceosome,rRNA processing,positive regulation of translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005524,GO:0003676,GO:0008026,GO:0005515,GO:0003729,GO:0004386,GO:0008143,GO:0004004,GO:0005737,GO:0005829,GO:0016607,GO:0035145,GO:0071013,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0051028,GO:0000398,GO:0006364,GO:0019221,GO:0045727,GO:0017148,GO:0000184","ATP binding,nucleic acid binding,ATP-dependent helicase activity,protein binding,mRNA binding,helicase activity,poly(A) RNA binding,ATP-dependent RNA helicase activity,cytoplasm,cytosol,nuclear speck,exon-exon junction complex,catalytic step 2 spliceosome,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,mRNA transport,mRNA splicing, via spliceosome,rRNA processing,cytokine-mediated signaling pathway,positive regulation of translation,negative regulation of translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["IGF2BP1","insulin-like growth factor 2 mRNA binding protein 1 [Source:HGNC Symbol;Acc:28866]","ENSG00000159217","ENSP00000290341",6,"RRM_1[1],KH_1[4],RRM_6[1]","family-297","IGF2BP1,IGF2BP3,IGF2BP2","IGF2BP1","IGF2BP3[75,74],IGF2BP2[68,65]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0003730,GO:0045182,GO:0048027,GO:0030529,GO:0010494,GO:0070937,GO:0051028,GO:0070934,GO:0010610,GO:0006403","RNA binding,mRNA binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,ribonucleoprotein complex,cytoplasmic stress granule,CRD-mediated mRNA stability complex,mRNA transport,CRD-mediated mRNA stabilization,regulation of mRNA stability involved in response to stress,RNA localization","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003729,GO:0003730,GO:0045182,GO:0048027,GO:0005634,GO:0005886,GO:0005737,GO:0030424,GO:0005829,GO:0048471,GO:0043231,GO:0030529,GO:0043197,GO:0030027,GO:0030175,GO:0030426,GO:0010494,GO:0070937,GO:0010467,GO:0051028,GO:0017148,GO:0042035,GO:0070934,GO:0010610,GO:0030425,GO:0006403","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,nucleus,plasma membrane,cytoplasm,axon,cytosol,perinuclear region of cytoplasm,intracellular membrane-bounded organelle,ribonucleoprotein complex,dendritic spine,lamellipodium,filopodium,growth cone,cytoplasmic stress granule,CRD-mediated mRNA stability complex,gene expression,mRNA transport,negative regulation of translation,regulation of cytokine biosynthetic process,CRD-mediated mRNA stabilization,regulation of mRNA stability involved in response to stress,dendrite,RNA localization","."]
["IGF2BP2","insulin-like growth factor 2 mRNA binding protein 2 [Source:HGNC Symbol;Acc:28867]","ENSG00000073792","ENSP00000320204",6,"RRM_1[2],KH_1[4]","family-297","IGF2BP1,IGF2BP3,IGF2BP2","IGF2BP1","IGF2BP3[75,74],IGF2BP2[68,65]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003730,GO:0045182,GO:0048027,GO:0051028","RNA binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,mRNA transport","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003730,GO:0045182,GO:0048027,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0010467,GO:0051028,GO:0017148,GO:0042035,GO:0009653","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,nucleus,cytoplasm,cytosol,cytoskeleton,gene expression,mRNA transport,negative regulation of translation,regulation of cytokine biosynthetic process,anatomical structure morphogenesis","."]
["IGF2BP3","insulin-like growth factor 2 mRNA binding protein 3 [Source:HGNC Symbol;Acc:28868]","ENSG00000136231","ENSP00000258729",6,"RRM_1[1],KH_1[4],RRM_6[1]","family-297","IGF2BP1,IGF2BP3,IGF2BP2","IGF2BP1","IGF2BP3[75,74],IGF2BP2[68,65]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003730,GO:0045182,GO:0048027,GO:0006412,GO:0051028","RNA binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,translation,mRNA transport","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0003730,GO:0045182,GO:0048027,GO:0005634,GO:0005737,GO:0005829,GO:0006412,GO:0010467,GO:0051028,GO:0017148,GO:0042035,GO:0009653","nucleotide binding,nucleic acid binding,RNA binding,protein binding,mRNA 3'-UTR binding,translation regulator activity,mRNA 5'-UTR binding,nucleus,cytoplasm,cytosol,translation,gene expression,mRNA transport,negative regulation of translation,regulation of cytokine biosynthetic process,anatomical structure morphogenesis","."]
["UBAP2","ubiquitin associated protein 2 [Source:HGNC Symbol;Acc:14185]","ENSG00000137073","ENSP00000368540",2,"DUF3697[1],UBA[1]","family-298","UBAP2,UBAP2L","UBAP2","UBAP2L[46,47]","mRNA","putative mRNA","22658674, 22681889, 23912277, RGG rich",".","novel",".",1,1,".",".",".","GO:0005515","protein binding","."]
["UBAP2L","ubiquitin associated protein 2-like [Source:HGNC Symbol;Acc:29877]","ENSG00000143569","ENSP00000345308",2,"DUF3697[1],UBA[1]","family-298","UBAP2,UBAP2L","UBAP2","UBAP2L[46,47]","mRNA","putative mRNA","22681889, 22658674, 23912277, RGG rich","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005671,GO:0007339","protein binding,Ada2/Gcn5/Ada3 transcription activator complex,binding of sperm to zona pellucida","."]
["SNRPE","small nuclear ribonucleoprotein polypeptide E [Source:HGNC Symbol;Acc:11161]","ENSG00000182004","ENSP00000400591",1,"LSM[1]","family-299","SNRPE",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0005681,GO:0000398,GO:0003723,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0016070,GO:0008380,GO:0000245,GO:0031124,GO:0000387,GO:0034660,GO:0008334","spliceosomal complex,mRNA splicing, via spliceosome,RNA binding,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,RNA metabolic process,RNA splicing,spliceosomal complex assembly,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,histone mRNA metabolic process","GO:0005681,GO:0000398,GO:0003723,GO:0005515,GO:0005634,GO:0005829,GO:0005654,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0006366,GO:0010467,GO:0016070,GO:0008380,GO:0000245,GO:0031124,GO:0000387,GO:0042633,GO:0034660,GO:0006369,GO:0008334","spliceosomal complex,mRNA splicing, via spliceosome,RNA binding,protein binding,nucleus,cytosol,nucleoplasm,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA splicing,spliceosomal complex assembly,mRNA 3'-end processing,spliceosomal snRNP assembly,hair cycle,ncRNA metabolic process,termination of RNA polymerase II transcription,histone mRNA metabolic process"," HYPOTRICHOSIS 11; HYPT11"]
["EIF2B5","eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa [Source:HGNC Symbol;Acc:3261]","ENSG00000145191","ENSP00000409142",3,"Hexapep[1],NTP_transferase[1],W2[1]","family-3","EIF2B5",".",".","mRNA","mRNA","eiF2B complex",".",".",".",".",".",".","GO:0031369,GO:0003743,GO:0005851,GO:0006417,GO:0006412,GO:0006413,GO:0045948","translation initiation factor binding,translation initiation factor activity,eukaryotic translation initiation factor 2B complex,regulation of translation,translation,translational initiation,positive regulation of translational initiation","GO:0005488,GO:0005515,GO:0031369,GO:0005634,GO:0009749,GO:0043434,GO:0032057,GO:0005085,GO:0003743,GO:0005737,GO:0005829,GO:0005851,GO:0006417,GO:0006412,GO:0014003,GO:0010467,GO:0001541,GO:0042552,GO:0048708,GO:0009408,GO:0035690,GO:0044267,GO:0034976,GO:0014002,GO:0006413,GO:0045948","binding,protein binding,translation initiation factor binding,nucleus,response to glucose,response to peptide hormone,negative regulation of translational initiation in response to stress,guanyl-nucleotide exchange factor activity,translation initiation factor activity,cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex,regulation of translation,translation,oligodendrocyte development,gene expression,ovarian follicle development,myelination,astrocyte differentiation,response to heat,cellular response to drug,cellular protein metabolic process,response to endoplasmic reticulum stress,astrocyte development,translational initiation,positive regulation of translational initiation"," LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER; VWM"]
["CRNKL1","crooked neck pre-mRNA splicing factor-like 1 (Drosophila) [Source:HGNC Symbol;Acc:15762]","ENSG00000101343","ENSP00000440733",4,"HAT[4]","family-30","CRNKL1",".",".","mRNA","mRNA","The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. A protein encoded by this human locus has been found to localize to pre-mRNA splicing complexes in the nucleus and is necessary for pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2013]","RNAbinding",".",".",1,".",".","GO:0003723,GO:0005681,GO:0071013,GO:0006397,GO:0000398,GO:0006396,GO:0000245","RNA binding,spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,mRNA splicing, via spliceosome,RNA processing,spliceosomal complex assembly","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005622,GO:0005681,GO:0016607,GO:0071013,GO:0006397,GO:0000398,GO:0006396,GO:0000245","RNA binding,protein binding,nucleus,cytoplasm,intracellular,spliceosomal complex,nuclear speck,catalytic step 2 spliceosome,mRNA processing,mRNA splicing, via spliceosome,RNA processing,spliceosomal complex assembly","."]
["POLRMT","polymerase (RNA) mitochondrial (DNA directed) [Source:HGNC Symbol;Acc:9200]","ENSG00000099821","ENSP00000465759",2,"RPOL_N[1],RNA_pol[1]","family-300","POLRMT",".",".","mRNA","mRNA","This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes. [provided by RefSeq, Jul 2008]","candidate mRNA binder","RNArelated",1,1,1,".",".",".","GO:0003677,GO:0003899,GO:0006351,GO:0005515,GO:0005739,GO:0005759,GO:0042645,GO:0010467,GO:0006390,GO:0006391","DNA binding,DNA-directed RNA polymerase activity,transcription, DNA-templated,protein binding,mitochondrion,mitochondrial matrix,mitochondrial nucleoid,gene expression,transcription from mitochondrial promoter,transcription initiation from mitochondrial promoter","."]
["METTL10","methyltransferase like 10 [Source:HGNC Symbol;Acc:33787]","ENSG00000203791","ENSP00000357829",1,"Methyltransf_31[1]","family-301","METTL10",".",".","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0008176,GO:0006400","tRNA (guanine-N7-)-methyltransferase activity,tRNA modification","GO:0008168,GO:0008276,GO:0008176,GO:0005737,GO:0008152,GO:0006479,GO:0006400","methyltransferase activity,protein methyltransferase activity,tRNA (guanine-N7-)-methyltransferase activity,cytoplasm,metabolic process,protein methylation,tRNA modification","."]
["MRPL41","mitochondrial ribosomal protein L41 [Source:HGNC Symbol;Acc:14492]","ENSG00000182154","ENSP00000360498",1,"MRP-L27[1]","family-302","MRPL41",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0030529,GO:0005762,GO:0006412","structural constituent of ribosome,ribonucleoprotein complex,mitochondrial large ribosomal subunit,translation","GO:0005515,GO:0003735,GO:0005739,GO:0030529,GO:0005762,GO:0006915,GO:0006412,GO:0007049","protein binding,structural constituent of ribosome,mitochondrion,ribonucleoprotein complex,mitochondrial large ribosomal subunit,apoptotic process,translation,cell cycle","."]
["MRPS7","mitochondrial ribosomal protein S7 [Source:HGNC Symbol;Acc:14499]","ENSG00000125445","ENSP00000463263",1,"Ribosomal_S7[1]","family-303","MRPS7",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0006412,GO:0003723,GO:0003735,GO:0022627","translation,RNA binding,structural constituent of ribosome,cytosolic small ribosomal subunit","GO:0006412,GO:0003723,GO:0003735,GO:0005739,GO:0022627","translation,RNA binding,structural constituent of ribosome,mitochondrion,cytosolic small ribosomal subunit","."]
["NSUN5","NOP2/Sun domain family, member 5 [Source:HGNC Symbol;Acc:16385]","ENSG00000130305","ENSP00000393081",1,"Nol1_Nop2_Fmu[1]","family-304","NSUN5,NSUN7","NSUN5","NSUN7[24,16]","rRNA","putative rRNA","by homology","candidate mRNA binder","novel",1,1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0008168","RNA binding,methyltransferase activity","."]
["NSUN7","NOP2/Sun domain family, member 7 [Source:HGNC Symbol;Acc:25857]","ENSG00000179299","ENSP00000371201",1,"Nol1_Nop2_Fmu[1]","family-304","NSUN5,NSUN7","NSUN5","NSUN7[24,16]","rRNA","putative rRNA","by homology",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0008168","RNA binding,methyltransferase activity","."]
["MTG1","Mitochondrial GTPase 1  [Source:UniProtKB/TrEMBL;Acc:E9PI62]","ENSG00000254536","ENSP00000436767",1,"MMR_HSR1[1]","family-305","MTG1",".",".","rRNA","putative rRNA","MTG1 yeast homolog",".",".",".",".",".",".","GO:0005761,GO:0042254","mitochondrial ribosome,ribosome biogenesis","GO:0005525,GO:0005634,GO:0005739,GO:0003924,GO:0005759,GO:0005743,GO:0005761,GO:0042254,GO:0044065,GO:0006184,GO:0070129","GTP binding,nucleus,mitochondrion,GTPase activity,mitochondrial matrix,mitochondrial inner membrane,mitochondrial ribosome,ribosome biogenesis,regulation of respiratory system process,GTP catabolic process,regulation of mitochondrial translation","."]
["MRPS28","mitochondrial ribosomal protein S28 [Source:HGNC Symbol;Acc:14513]","ENSG00000147586","ENSP00000430401",1,"MRP-S35[1]","family-306","MRPS28",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0005763","mitochondrial small ribosomal subunit","GO:0005739,GO:0005763","mitochondrion,mitochondrial small ribosomal subunit","."]
["TDRD10","tudor domain containing 10 [Source:HGNC Symbol;Acc:25316]","ENSG00000163239","ENSP00000357467",2,"TUDOR[1],RRM_6[1]","family-307","TDRD10",".",".","unknown","RNA related","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["RPUSD1","RNA pseudouridylate synthase domain containing 1 [Source:HGNC Symbol;Acc:14173]","ENSG00000007376","ENSP00000456692",1,"PseudoU_synth_2[1]","family-308","RPUSD1",".",".","tRNA","putative tRNA/rRNA","PUS6 yeast homolog",".",".",".",".",".",".","GO:0003723,GO:0009451","RNA binding,RNA modification","GO:0003723,GO:0009982,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification","."]
["NHP2","NHP2 ribonucleoprotein [Source:HGNC Symbol;Acc:14377]","ENSG00000145912","ENSP00000423803",1,"Ribosomal_L7Ae[1]","family-309","NHP2",".",".","snoRNA","snoRNA","established RBP ",".","RNAbinding",".",1,1,".","GO:0003723,GO:0030515,GO:0005732,GO:0031118","RNA binding,snoRNA binding,small nucleolar ribonucleoprotein complex,rRNA pseudouridine synthesis","GO:0003723,GO:0005730,GO:0030515,GO:0015030,GO:0005732,GO:0031118","RNA binding,nucleolus,snoRNA binding,Cajal body,small nucleolar ribonucleoprotein complex,rRNA pseudouridine synthesis"," DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 2; DKCB2"]
["XAB2","XPA binding protein 2 [Source:HGNC Symbol;Acc:14089]","ENSG00000076924","ENSP00000351137",2,"TPR_2[1],TPR_12[1]","family-31","XAB2",".",".","mRNA","putative mRNA",17981804,".",".",".",".",".",".","GO:0006396,GO:0071013,GO:0000398","RNA processing,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0005622,GO:0006396,GO:0001824,GO:0005634,GO:0005654,GO:0071013,GO:0006351,GO:0006289,GO:0006281,GO:0000398,GO:0006283","protein binding,intracellular,RNA processing,blastocyst development,nucleus,nucleoplasm,catalytic step 2 spliceosome,transcription, DNA-templated,nucleotide-excision repair,DNA repair,mRNA splicing, via spliceosome,transcription-coupled nucleotide-excision repair","."]
["FAU","Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed [Source:HGNC Symbol;Acc:3597]","ENSG00000149806","ENSP00000435370",2,"ubiquitin[1],Ribosomal_S30[1]","family-310","FAU",".",".","ribosome","ribosome","established RBP ","RNAbinding",".",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022627,GO:0015935,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic small ribosomal subunit,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022627,GO:0015935,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","protein binding,structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,cytosol,cytosolic small ribosomal subunit,small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RRP36","ribosomal RNA processing 36 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:21374]","ENSG00000124541","ENSP00000244496",1,"DUF947[1]","family-311","RRP36",".",".","rRNA","putative rRNA","RRP36 functions at an early stage in the processing of 35S preribosomal RNA into the mature 18S species (Gerus et al., 2010 [PubMed 20038530]).[supplied by OMIM, Jul 2010]","candidate mRNA binder","RNArelated",1,1,1,".","GO:0006364,GO:0042274","rRNA processing,ribosomal small subunit biogenesis","GO:0005730,GO:0006364,GO:0042274","nucleolus,rRNA processing,ribosomal small subunit biogenesis","."]
["GRWD1","glutamate-rich WD repeat containing 1 [Source:HGNC Symbol;Acc:21270]","ENSG00000105447","ENSP00000253237",4,"CAF1C_H4-bd[1],WD40[3]","family-312","GRWD1",".",".","rRNA","rRNA","RRB1 yeast homolog This gene encodes a glutamate-rich protein that contains five WD-repeat motifs. The encoded protein may play a critical role in ribosome biogenesis and may also play a role in histone methylation through interactions with CUL4-DDB1 ubiquitin E3 ligase. [provided by RefSeq, Feb 2012]","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005634,GO:0005737,GO:0005730","protein binding,nucleus,cytoplasm,nucleolus","."]
["ENDOV","endonuclease V [Source:HGNC Symbol;Acc:26640]","ENSG00000173818","ENSP00000429190",1,"Endonuclease_5[1]","family-313","ENDOV",".",".","tRNA","tRNA",23912683,".",".",".",".",".",".","GO:0003727,GO:0016891","single-stranded RNA binding,endoribonuclease activity, producing 5'-phosphomonoesters","GO:0004519,GO:0006281,GO:0000287,GO:0016888,GO:0003727,GO:0043566,GO:0016891,GO:0005737,GO:0005730","endonuclease activity,DNA repair,magnesium ion binding,endodeoxyribonuclease activity, producing 5'-phosphomonoesters,single-stranded RNA binding,structure-specific DNA binding,endoribonuclease activity, producing 5'-phosphomonoesters,cytoplasm,nucleolus","."]
["VARSL","Valine--tRNA ligase, mitochondrial; Valyl-tRNA synthetase like  [Source:UniProtKB/TrEMBL;Acc:A2ABL6]","ENSG00000206476","ENSP00000446608",2,"Anticodon_1[1],tRNA-synt_1[1]","family-314","VARSL",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004832,GO:0002161,GO:0004812,GO:0006418,GO:0006438","valine-tRNA ligase activity,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004832,GO:0002161,GO:0004812,GO:0006418,GO:0006438,GO:0005739","nucleotide binding,ATP binding,valine-tRNA ligase activity,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valyl-tRNA aminoacylation,mitochondrion","."]
["MRRF","mitochondrial ribosome recycling factor [Source:HGNC Symbol;Acc:7234]","ENSG00000148187","ENSP00000395072",1,"RRF[1]","family-315","MRRF",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0006412,GO:0032790","translation,ribosome disassembly","GO:0005739,GO:0006412,GO:0032790","mitochondrion,translation,ribosome disassembly","."]
["MTFMT","mitochondrial methionyl-tRNA formyltransferase [Source:HGNC Symbol;Acc:29666]","ENSG00000103707","ENSP00000220058",2,"Formyl_trans_N[1],Formyl_trans_C[1]","family-316","MTFMT",".",".","tRNA","tRNA","The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011]",".",".",".",".",".",".","GO:0004479,GO:0071951","methionyl-tRNA formyltransferase activity,conversion of methionyl-tRNA to N-formyl-methionyl-tRNA","GO:0016742,GO:0005739,GO:0009058,GO:0003824,GO:0004479,GO:0071951","hydroxymethyl-, formyl- and related transferase activity,mitochondrion,biosynthetic process,catalytic activity,methionyl-tRNA formyltransferase activity,conversion of methionyl-tRNA to N-formyl-methionyl-tRNA"," LEIGH SYNDROME; LS"]
["C12orf65","chromosome 12 open reading frame 65 [Source:HGNC Symbol;Acc:26784]","ENSG00000130921","ENSP00000390647",1,"RF-1[1]","family-317","C12orf65",".",".","mRNA","putative mRNA","established RBP ",".",".",".",".",".",".","GO:0003747,GO:0006415","translation release factor activity,translational termination","GO:0003747,GO:0005739,GO:0008219,GO:0006415","translation release factor activity,mitochondrion,cell death,translational termination"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 7; COXPD7"]
["MRTO4","mRNA turnover 4 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:18477]","ENSG00000053372","ENSP00000364320",1,"Ribosomal_L10[1]","family-318","MRTO4",".",".","mRNA","mRNA","This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. While the precise function of the encoded protein is currently unknown, it appears to be involved in mRNA turnover and ribosome assembly. [provided by RefSeq, Jul 2008]","RNAbinding","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005634,GO:0005622,GO:0005730,GO:0031965,GO:0042254","nucleus,intracellular,nucleolus,nuclear membrane,ribosome biogenesis","."]
["RBM26","RNA binding motif protein 26 [Source:HGNC Symbol;Acc:20327]","ENSG00000139746","ENSP00000267229",4,"RRM_5[1],PWI[1],zf-CCCH[1],RRM_6[1]","family-319","RBM26,RBM27","RBM26","RBM27[46,42]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0046872,GO:0006397,GO:0010923","nucleotide binding,RNA binding,protein binding,nucleic acid binding,metal ion binding,mRNA processing,negative regulation of phosphatase activity","."]
["RBM27","RNA binding motif protein 27 [Source:HGNC Symbol;Acc:29243]","ENSG00000091009","ENSP00000265271",3,"RRM_5[1],PWI[1],zf-CCCH[1]","family-319","RBM26,RBM27","RBM26","RBM27[46,42]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0046872,GO:0005634,GO:0005737,GO:0016607,GO:0006397","nucleotide binding,RNA binding,nucleic acid binding,metal ion binding,nucleus,cytoplasm,nuclear speck,mRNA processing","."]
["DIS3","DIS3 mitotic control homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20604]","ENSG00000083520","ENSP00000367011",2,"PIN_4[1],RNB[1]","family-32","DIS3,DIS3L,DIS3L2","DIS3","DIS3L[36,32],DIS3L2[26,29]","diverse","diverse","established RBP ",".",".",".",".",1,".","GO:0003723,GO:0000175,GO:0000178,GO:0000176,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0016075,GO:0043928,GO:0071034","RNA binding,3'-5'-exoribonuclease activity,exosome (RNase complex),nuclear exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,rRNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,CUT catabolic process","GO:0003723,GO:0005515,GO:0004519,GO:0005085,GO:0000175,GO:0005829,GO:0000178,GO:0005654,GO:0000176,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0016075,GO:0043928,GO:0071034","RNA binding,protein binding,endonuclease activity,guanyl-nucleotide exchange factor activity,3'-5'-exoribonuclease activity,cytosol,exosome (RNase complex),nucleoplasm,nuclear exosome (RNase complex),gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,rRNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,CUT catabolic process","."]
["DIS3L","DIS3 mitotic control homolog (S. cerevisiae)-like [Source:HGNC Symbol;Acc:28698]","ENSG00000166938","ENSP00000321711",1,"RNB[1]","family-32","DIS3,DIS3L,DIS3L2","DIS3","DIS3L[36,32],DIS3L2[26,29]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000175,GO:0000177,GO:0016075","RNA binding,3'-5'-exoribonuclease activity,cytoplasmic exosome (RNase complex),rRNA catabolic process","GO:0005886,GO:0005737,GO:0005813,GO:0003723,GO:0005515,GO:0019899,GO:0000175,GO:0000177,GO:0016075","plasma membrane,cytoplasm,centrosome,RNA binding,protein binding,enzyme binding,3'-5'-exoribonuclease activity,cytoplasmic exosome (RNase complex),rRNA catabolic process","."]
["DIS3L2","DIS3 mitotic control homolog (S. cerevisiae)-like 2 [Source:HGNC Symbol;Acc:28648]","ENSG00000144535","ENSP00000390467",1,"OB_RNB[1]","family-32","DIS3,DIS3L,DIS3L2","DIS3","DIS3L[36,32],DIS3L2[26,29]","diverse","miRNA/mRNA","The protein encoded by this gene is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Mar 2012]",".",".",".",".",".",".","GO:0003723,GO:0004540,GO:0000175,GO:0000932,GO:0010587","RNA binding,ribonuclease activity,3'-5'-exoribonuclease activity,cytoplasmic mRNA processing body,miRNA catabolic process","GO:0003723,GO:0005515,GO:0004540,GO:0000175,GO:0005737,GO:0000932,GO:0005844,GO:0008285,GO:0007067,GO:0019827,GO:0010587,GO:0051306,GO:0000291,GO:0034427,GO:1990074","RNA binding,protein binding,ribonuclease activity,3'-5'-exoribonuclease activity,cytoplasm,cytoplasmic mRNA processing body,polysome,negative regulation of cell proliferation,mitosis,stem cell maintenance,miRNA catabolic process,mitotic sister chromatid separation,nuclear-transcribed mRNA catabolic process, exonucleolytic,nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5',polyuridylation-dependent mRNA catabolic process"," PERLMAN SYNDROME; PRLMNS"]
["C1QBP","complement component 1, q subcomponent binding protein [Source:HGNC Symbol;Acc:1243]","ENSG00000108561","ENSP00000225698",1,"MAM33[1]","family-320","C1QBP",".",".","mRNA","mRNA",22904065,".",".",".",".",".",".","GO:0003729,GO:0097177,GO:0006397,GO:0008380,GO:0042256,GO:0048025,GO:0070131","mRNA binding,mitochondrial ribosome binding,mRNA processing,RNA splicing,mature ribosome assembly,negative regulation of mRNA splicing, via spliceosome,positive regulation of mitochondrial translation","GO:0005080,GO:0001849,GO:0005634,GO:0005615,GO:0005759,GO:0031690,GO:0005515,GO:0003714,GO:0003729,GO:0008134,GO:0005540,GO:0030984,GO:0097177,GO:0005739,GO:0005737,GO:0005886,GO:0016020,GO:0005829,GO:0009986,GO:0005730,GO:0000122,GO:0006351,GO:0006958,GO:0045087,GO:0006915,GO:0045785,GO:0032689,GO:0006955,GO:0006397,GO:0008380,GO:0043065,GO:0007596,GO:0051897,GO:0042256,GO:0039536,GO:0014065,GO:1900026,GO:0032695,GO:0090023,GO:0048025,GO:0019048,GO:2000510,GO:0050687,GO:0007597,GO:0030449,GO:1901165,GO:0039534,GO:0070131","protein kinase C binding,complement component C1q binding,nucleus,extracellular space,mitochondrial matrix,adrenergic receptor binding,protein binding,transcription corepressor activity,mRNA binding,transcription factor binding,hyaluronic acid binding,kininogen binding,mitochondrial ribosome binding,mitochondrion,cytoplasm,plasma membrane,membrane,cytosol,cell surface,nucleolus,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,complement activation, classical pathway,innate immune response,apoptotic process,positive regulation of cell adhesion,negative regulation of interferon-gamma production,immune response,mRNA processing,RNA splicing,positive regulation of apoptotic process,blood coagulation,positive regulation of protein kinase B signaling,mature ribosome assembly,negative regulation of RIG-I signaling pathway,phosphatidylinositol 3-kinase signaling,positive regulation of substrate adhesion-dependent cell spreading,negative regulation of interleukin-12 production,positive regulation of neutrophil chemotaxis,negative regulation of mRNA splicing, via spliceosome,modulation by virus of host morphology or physiology,positive regulation of dendritic cell chemotaxis,negative regulation of defense response to virus,blood coagulation, intrinsic pathway,regulation of complement activation,positive regulation of trophoblast cell migration,negative regulation of MDA-5 signaling pathway,positive regulation of mitochondrial translation","."]
["SUB1","SUB1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:19985]","ENSG00000113387","ENSP00000426850",1,"PC4[1]","family-321","SUB1",".",".","mRNA","putative mRNA",20305379,"candidate mRNA binder","RNArelated",1,1,1,".",".",".","GO:0005515,GO:0003677,GO:0003697,GO:0003713,GO:0005634,GO:0005667,GO:0005730,GO:0006351,GO:0006355,GO:0006357","protein binding,DNA binding,single-stranded DNA binding,transcription coactivator activity,nucleus,transcription factor complex,nucleolus,transcription, DNA-templated,regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter","."]
["MRPS33","mitochondrial ribosomal protein S33 [Source:HGNC Symbol;Acc:16634]","ENSG00000090263","ENSP00000376732",1,"MRP-S33[1]","family-322","MRPS33",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","GO:0005739,GO:0003735,GO:0005763,GO:0006412","mitochondrion,structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","."]
["PRPF6","PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15860]","ENSG00000101161","ENSP00000266079",4,"TPR_19[2],TPR_14[1],PRP1_N[1]","family-323","PRPF6",".",".","snRNA","snRNA/mRNA","established RBP ",".","RNArelated",".",1,".",".","GO:0003723,GO:0043021,GO:0005681,GO:0046540,GO:0071001,GO:0071013,GO:0005682,GO:0008380,GO:0000398,GO:0006396,GO:0000245,GO:0000375,GO:0006403","RNA binding,ribonucleoprotein complex binding,spliceosomal complex,U4/U6 x U5 tri-snRNP complex,U4/U6 snRNP,catalytic step 2 spliceosome,U5 snRNP,RNA splicing,mRNA splicing, via spliceosome,RNA processing,spliceosomal complex assembly,RNA splicing, via transesterification reactions,RNA localization","GO:0003723,GO:0005515,GO:0003713,GO:0043021,GO:0050681,GO:0005634,GO:0005622,GO:0005654,GO:0005681,GO:0046540,GO:0016607,GO:0071001,GO:0071013,GO:0005682,GO:0045944,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0000245,GO:0000244,GO:0000375,GO:0006403","RNA binding,protein binding,transcription coactivator activity,ribonucleoprotein complex binding,androgen receptor binding,nucleus,intracellular,nucleoplasm,spliceosomal complex,U4/U6 x U5 tri-snRNP complex,nuclear speck,U4/U6 snRNP,catalytic step 2 spliceosome,U5 snRNP,positive regulation of transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,spliceosomal complex assembly,spliceosomal tri-snRNP complex assembly,RNA splicing, via transesterification reactions,RNA localization"," RETINITIS PIGMENTOSA 60; RP60"]
["SMG8","smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:25551]","ENSG00000167447","ENSP00000438748",2,"DUF2146[2]","family-324","SMG8",".",".","mRNA","mRNA",19417104,".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0000184","RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0045859,GO:0000184","protein binding,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,regulation of protein kinase activity,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["PSTK","phosphoseryl-tRNA kinase [Source:HGNC Symbol;Acc:28578]","ENSG00000179988","ENSP00000357882",2,"KTI12[2]","family-325","PSTK",".",".","tRNA","tRNA",15317934,".",".",".",".",".",".","GO:0000049","tRNA binding","GO:0005524,GO:0000049,GO:0016301,GO:0005739,GO:0097056,GO:0001514","ATP binding,tRNA binding,kinase activity,mitochondrion,selenocysteinyl-tRNA(Sec) biosynthetic process,selenocysteine incorporation","."]
["GAPDH","glyceraldehyde-3-phosphate dehydrogenase [Source:HGNC Symbol;Acc:4141]","ENSG00000111640","ENSP00000229239",2,"Gp_dh_C[1],Gp_dh_N[1]","family-326","GAPDH,GAPDHS","GAPDH","GAPDHS[67,55]","mRNA","mRNA/teloRNA","7531693, 21236242",".",".",".",".",".",1,"GO:0030529","ribonucleoprotein complex","GO:0005515,GO:0050661,GO:0008017,GO:0042802,GO:0051287,GO:0016620,GO:0004365,GO:0035605,GO:0005634,GO:0005886,GO:0005737,GO:0005829,GO:0048471,GO:0015630,GO:0030529,GO:0070062,GO:0005811,GO:0097452,GO:0055114,GO:0044281,GO:0005975,GO:0006096,GO:0071346,GO:0006006,GO:0000226,GO:0051402,GO:0006094,GO:0017148,GO:0050821,GO:0035606","protein binding,NADP binding,microtubule binding,identical protein binding,NAD binding,oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor,glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity,peptidyl-cysteine S-nitrosylase activity,nucleus,plasma membrane,cytoplasm,cytosol,perinuclear region of cytoplasm,microtubule cytoskeleton,ribonucleoprotein complex,extracellular vesicular exosome,lipid particle,GAIT complex,oxidation-reduction process,small molecule metabolic process,carbohydrate metabolic process,glycolysis,cellular response to interferon-gamma,glucose metabolic process,microtubule cytoskeleton organization,neuron apoptotic process,gluconeogenesis,negative regulation of translation,protein stabilization,peptidyl-cysteine S-trans-nitrosylation","."]
["TNPO3","transportin 3 [Source:HGNC Symbol;Acc:17103]","ENSG00000064419","ENSP00000418267",1,"Xpo1[1]","family-327","IPO13,TNPO3","IPO13","TNPO3[21,22]","mRNA","mRBP transport",12628928,".",".",".",".",".",".","GO:0035048","splicing factor protein import into nucleus","GO:0005488,GO:0005634,GO:0043231,GO:0006810,GO:0005515,GO:0004872,GO:0005737,GO:0035048","binding,nucleus,intracellular membrane-bounded organelle,transport,protein binding,receptor activity,cytoplasm,splicing factor protein import into nucleus","."]
["IPO13","importin 13 [Source:HGNC Symbol;Acc:16853]","ENSG00000117408","ENSP00000361418",2,"IBN_N[1],Xpo1[1]","family-327","IPO13,TNPO3","IPO13","TNPO3[21,22]","mRNA","putative mRBP transport","This gene encodes a member of the importin-beta family of nuclear transport proteins. The encoded protein mediates the import of specific cargo proteins from the cytoplasm to the nucleus and is dependent on the Ras-related nuclear protein-GTPase system. The encoded protein is also involved in nuclear export of the eukaryotic translation initiation factor 1A.[provided by RefSeq, Mar 2009]",".",".",".",".",".",".",".",".","GO:0005515,GO:0008536,GO:0005488,GO:0005634,GO:0005737,GO:0006886,GO:0006606","protein binding,Ran GTPase binding,binding,nucleus,cytoplasm,intracellular protein transport,protein import into nucleus","."]
["MOV10","Mov10, Moloney leukemia virus 10, homolog (mouse) [Source:HGNC Symbol;Acc:7200]","ENSG00000155363","ENSP00000399797",3,"AAA_19[1],AAA_11[1],AAA_12[1]","family-328","MOV10,MOV10L1","MOV10","MOV10L1[32,26]","mRNA","mRNA","established RBP ","helicase","experimentally validated",1,1,1,".","GO:0003723,GO:0000932,GO:0035279","RNA binding,cytoplasmic mRNA processing body,mRNA cleavage involved in gene silencing by miRNA","GO:0003723,GO:0005515,GO:0005524,GO:0004386,GO:0005829,GO:0000932,GO:0006351,GO:0038095,GO:0045087,GO:0006355,GO:0048015,GO:0007219,GO:0008543,GO:0007173,GO:0048011,GO:0035279","RNA binding,protein binding,ATP binding,helicase activity,cytosol,cytoplasmic mRNA processing body,transcription, DNA-templated,Fc-epsilon receptor signaling pathway,innate immune response,regulation of transcription, DNA-dependent,phosphatidylinositol-mediated signaling,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,mRNA cleavage involved in gene silencing by miRNA","."]
["MOV10L1","Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse) [Source:HGNC Symbol;Acc:7201]","ENSG00000073146","ENSP00000438978",4,"AAA_11[2],AAA_12[1],S1-like[1]","family-328","MOV10,MOV10L1","MOV10","MOV10L1[32,26]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0004004","RNA binding,ATP-dependent RNA helicase activity","GO:0003723,GO:0005524,GO:0000287,GO:0004004,GO:0005622,GO:0007275,GO:0007283,GO:0007281","RNA binding,ATP binding,magnesium ion binding,ATP-dependent RNA helicase activity,intracellular,multicellular organismal development,spermatogenesis,germ cell development","."]
["PARP1","poly (ADP-ribose) polymerase 1 [Source:HGNC Symbol;Acc:270]","ENSG00000143799","ENSP00000355759",7,"BRCT[1],WGR[1],PARP_reg[1],zf-PARP[2],PARP[1],PADR1[1]","family-329","PARP1,PARP2,PARP3","PARP1","PARP2[19,33],PARP3[16,31]","mRNA","putative mRNA","24510188, 23219533","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0008270,GO:0003677,GO:0005515,GO:0003950,GO:0019899,GO:0070412,GO:0008134,GO:0042802,GO:0051287,GO:0047485,GO:0005730,GO:0005654,GO:0043234,GO:0005634,GO:0005667,GO:0005635,GO:0006259,GO:0023019,GO:0006471,GO:0060391,GO:0007179,GO:0070212,GO:2000679,GO:0045944,GO:0000122,GO:0006351,GO:0006366,GO:0006284,GO:0006281,GO:0010467,GO:0006367,GO:0000723,GO:0032869,GO:0006302,GO:0030225,GO:0016540,GO:0040009,GO:0042769","zinc ion binding,DNA binding,protein binding,NAD+ ADP-ribosyltransferase activity,enzyme binding,R-SMAD binding,transcription factor binding,identical protein binding,NAD binding,protein N-terminus binding,nucleolus,nucleoplasm,protein complex,nucleus,transcription factor complex,nuclear envelope,DNA metabolic process,signal transduction involved in regulation of gene expression,protein ADP-ribosylation,positive regulation of SMAD protein import into nucleus,transforming growth factor beta receptor signaling pathway,protein poly-ADP-ribosylation,positive regulation of transcription regulatory region DNA binding,positive regulation of transcription from RNA polymerase II promoter,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,transcription from RNA polymerase II promoter,base-excision repair,DNA repair,gene expression,transcription initiation from RNA polymerase II promoter,telomere maintenance,cellular response to insulin stimulus,double-strand break repair,macrophage differentiation,protein autoprocessing,regulation of growth rate,DNA damage response, detection of DNA damage","."]
["MRPS35","mitochondrial ribosomal protein S35 [Source:HGNC Symbol;Acc:16635]","ENSG00000061794","ENSP00000081029",1,"MRP-S28[1]","family-33","MRPS35",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0005763","mitochondrial small ribosomal subunit","GO:0005763,GO:0043043,GO:0042769,GO:0005739","mitochondrial small ribosomal subunit,peptide biosynthetic process,DNA damage response, detection of DNA damage,mitochondrion","."]
["GPKOW","G patch domain and KOW motifs [Source:HGNC Symbol;Acc:30677]","ENSG00000268675","ENSP00000471681",3,"KOW[2],G-patch_2[1]","family-330","GPKOW",".",".","unknown","unknown",21880142,".",".",".",".",".",".",".",".","GO:0005515,GO:0003676,GO:0005634","protein binding,nucleic acid binding,nucleus","."]
["SETD1A","SET domain containing 1A [Source:HGNC Symbol;Acc:29010]","ENSG00000099381","ENSP00000262519",3,"SET[1],RRM_1[1],N-SET[1]","family-331","SETD1A,SETD1B","SETD1A","SETD1B[41,37]","ncRNA","putative ncRNA/snoRNA",15775977,".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0018024,GO:0003723,GO:0005515,GO:0042800,GO:0005634,GO:0005694,GO:0035097,GO:0016607,GO:0048188,GO:0006351,GO:0006355,GO:0051568","nucleotide binding,nucleic acid binding,histone-lysine N-methyltransferase activity,RNA binding,protein binding,histone methyltransferase activity (H3-K4 specific),nucleus,chromosome,histone methyltransferase complex,nuclear speck,Set1C/COMPASS complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,histone H3-K4 methylation","."]
["SETD1B","SET domain containing 1B [Source:HGNC Symbol;Acc:29187]","ENSG00000139718","ENSP00000442924",3,"SET[1],RRM_1[1],N-SET[1]","family-331","SETD1A,SETD1B","SETD1A","SETD1B[41,37]","ncRNA","putative ncRNA/snoRNA","21955586, 21874018 , 15556860",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0042800,GO:0005634,GO:0005694,GO:0035097,GO:0016607,GO:0048188,GO:0006351,GO:0006355,GO:0051568,GO:0018024","nucleotide binding,RNA binding,protein binding,nucleic acid binding,histone methyltransferase activity (H3-K4 specific),nucleus,chromosome,histone methyltransferase complex,nuclear speck,Set1C/COMPASS complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,histone H3-K4 methylation,histone-lysine N-methyltransferase activity","."]
["SF3A2","splicing factor 3a, subunit 2, 66kDa [Source:HGNC Symbol;Acc:10766]","ENSG00000104897","ENSP00000221494",2,"CactinC_cactus[1],zf-met[1]","family-332","SF3A2",".",".","snRNA","snRNA","This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,".",".","GO:0005681,GO:0030532,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0000389","spliceosomal complex,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-splice site recognition","GO:0008270,GO:0003676,GO:0005634,GO:0005515,GO:0005654,GO:0005681,GO:0030532,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0000389","zinc ion binding,nucleic acid binding,nucleus,protein binding,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-splice site recognition","."]
["AFF1","AF4/FMR2 family, member 1 [Source:HGNC Symbol;Acc:7135]","ENSG00000172493","ENSP00000378578",1,"AF-4[1]","family-333","AFF1,AFF4,AFF2,AFF3","AFF1","AFF4[38,39],AFF2[31,29],AFF3[31,30]","mRNA","putative mRNA",21330300,".",".",".",".",".",".",".",".","GO:0005634,GO:0045893,GO:0003700,GO:0005515","nucleus,positive regulation of transcription, DNA-dependent,sequence-specific DNA binding transcription factor activity,protein binding","."]
["AFF3","AF4/FMR2 family, member 3 [Source:HGNC Symbol;Acc:6473]","ENSG00000144218","ENSP00000411383",1,"AF-4[1]","family-333","AFF1,AFF4,AFF2,AFF3","AFF1","AFF4[38,39],AFF2[31,29],AFF3[31,30]","mRNA","putative mRNA",21330300,".",".",".",".",".",".",".",".","GO:0003690,GO:0005634,GO:0005730,GO:0006351,GO:0006355,GO:0035116,GO:0034612","double-stranded DNA binding,nucleus,nucleolus,transcription, DNA-templated,regulation of transcription, DNA-dependent,embryonic hindlimb morphogenesis,response to tumor necrosis factor","."]
["AFF4","AF4/FMR2 family, member 4 [Source:HGNC Symbol;Acc:17869]","ENSG00000072364","ENSP00000395268",1,"AF-4[1]","family-333","AFF1,AFF4,AFF2,AFF3","AFF1","AFF4[38,39],AFF2[31,29],AFF3[31,30]","mRNA","putative mRNA",21330300,".",".",".",".",".",".",".",".","GO:0005634,GO:0007286,GO:0003700,GO:0005515,GO:0005739,GO:0005730,GO:0006366","nucleus,spermatid development,sequence-specific DNA binding transcription factor activity,protein binding,mitochondrion,nucleolus,transcription from RNA polymerase II promoter","."]
["AFF2","AF4/FMR2 family, member 2 [Source:HGNC Symbol;Acc:3776]","ENSG00000269754","ENSP00000472279",1,"AF-4[1]","family-333","AFF1,AFF4,AFF2,AFF3","AFF1","AFF4[38,39],AFF2[31,29],AFF3[31,30]","mRNA","putative mRNA",21330300,".",".",".",".",".",".","GO:0002151,GO:0006397,GO:0008380,GO:0043484","G-quadruplex RNA binding,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0002151,GO:0016607,GO:0007420,GO:0007611,GO:0006397,GO:0008380,GO:0043484","G-quadruplex RNA binding,nuclear speck,brain development,learning or memory,mRNA processing,RNA splicing,regulation of RNA splicing"," MENTAL RETARDATION, X-LINKED, ASSOCIATED WITH FRAGILE SITE FRAXE"]
["PARK7","parkinson protein 7 [Source:HGNC Symbol;Acc:16369]","ENSG00000116288","ENSP00000418770",1,"DJ-1_PfpI[1]","family-334","PARK7",".",".","mRNA","mRNA",18626009,".",".",".",".",".",".","GO:0003729","mRNA binding","GO:0005515,GO:0042803,GO:0004601,GO:0003729,GO:0008233,GO:0051920,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0006508,GO:0006914,GO:0006954,GO:0070301,GO:0007338,GO:0032091,GO:0043524,GO:0007005,GO:0060548,GO:0043523,GO:0008344,GO:0008219,GO:0050821,GO:0050727,GO:0051899,GO:0060081,GO:2001237,GO:0060765,GO:0051583,GO:0042743,GO:2000277,GO:0001963,GO:0034614,GO:0042542,GO:0034599","protein binding,protein homodimerization activity,peroxidase activity,mRNA binding,peptidase activity,peroxiredoxin activity,nucleus,cytoplasm,mitochondrion,cytosol,proteolysis,autophagy,inflammatory response,cellular response to hydrogen peroxide,single fertilization,negative regulation of protein binding,negative regulation of neuron apoptotic process,mitochondrion organization,negative regulation of cell death,regulation of neuron apoptotic process,adult locomotory behavior,cell death,protein stabilization,regulation of inflammatory response,membrane depolarization,membrane hyperpolarization,negative regulation of extrinsic apoptotic signaling pathway,regulation of androgen receptor signaling pathway,dopamine uptake involved in synaptic transmission,hydrogen peroxide metabolic process,positive regulation of oxidative phosphorylation uncoupler activity,synaptic transmission, dopaminergic,cellular response to reactive oxygen species,response to hydrogen peroxide,cellular response to oxidative stress"," PARKINSON DISEASE, LATE-ONSET; PD"]
["TRNAU1AP","tRNA selenocysteine 1 associated protein 1 [Source:HGNC Symbol;Acc:30813]","ENSG00000180098","ENSP00000362936",2,"RRM_1[2]","family-335","C6orf52,TRNAU1AP","C6orf52","TRNAU1AP[29,15]","tRNA","tRNA",10606267,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0005515,GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005737,GO:0001514","protein binding,nucleotide binding,RNA binding,nucleic acid binding,nucleus,cytoplasm,selenocysteine incorporation","."]
["SRBD1","S1 RNA binding domain 1 [Source:HGNC Symbol;Acc:25521]","ENSG00000068784","ENSP00000263736",4,"S1[1],YqgF[1],HHH_3[1],Tex_N[1]","family-336","SRBD1",".",".","unknown","unknown","various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0016788,GO:0006139","RNA binding,hydrolase activity, acting on ester bonds,nucleobase-containing compound metabolic process","."]
["EIF3D","eukaryotic translation initiation factor 3, subunit D [Source:HGNC Symbol;Acc:3278]","ENSG00000100353","ENSP00000216190",1,"eIF-3_zeta[1]","family-337","EIF3D",".",".","mRNA","mRNA",24092755,"translationfactor","novel",1,1,1,".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0001732,GO:0006412,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,formation of translation initiation complex,translation,translational initiation","GO:0003743,GO:0005737,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0001732,GO:0005515,GO:0005829,GO:0006412,GO:0010467,GO:0044267,GO:0006413","translation initiation factor activity,cytoplasm,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,formation of translation initiation complex,protein binding,cytosol,translation,gene expression,cellular protein metabolic process,translational initiation","."]
["NOP10","NOP10 ribonucleoprotein [Source:HGNC Symbol;Acc:14378]","ENSG00000182117","ENSP00000453475",1,"Nop10p[1]","family-338","NOP10",".",".","snoRNA","snoRNA","established RBP ",".",".",".",".",".",".","GO:0030515,GO:0005732,GO:0072588,GO:0042254,GO:0006364","snoRNA binding,small nucleolar ribonucleoprotein complex,box H/ACA RNP complex,ribosome biogenesis,rRNA processing","GO:0005515,GO:0030515,GO:0005730,GO:0015030,GO:0005732,GO:0072588,GO:0042254,GO:0006364,GO:0001522","protein binding,snoRNA binding,nucleolus,Cajal body,small nucleolar ribonucleoprotein complex,box H/ACA RNP complex,ribosome biogenesis,rRNA processing,pseudouridine synthesis"," DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 1; DKCB1"]
["WARS","tryptophanyl-tRNA synthetase [Source:HGNC Symbol;Acc:12729]","ENSG00000140105","ENSP00000452519",2,"tRNA-synt_1b[1],WHEP-TRS[1]","family-339","WARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0006418,GO:0004830,GO:0006436,GO:0006412","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,tryptophan-tRNA ligase activity,tryptophanyl-tRNA aminoacylation,translation","GO:0005524,GO:0004812,GO:0006418,GO:0004830,GO:0005737,GO:0006436,GO:0000166,GO:0005515,GO:0005829,GO:0008285,GO:0006412,GO:0001525,GO:0010467,GO:0045765","ATP binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,tryptophan-tRNA ligase activity,cytoplasm,tryptophanyl-tRNA aminoacylation,nucleotide binding,protein binding,cytosol,negative regulation of cell proliferation,translation,angiogenesis,gene expression,regulation of angiogenesis","."]
["MATR3","matrin 3 [Source:HGNC Symbol;Acc:6912]","ENSG00000015479","ENSP00000378279",2,"RRM_5[2]","family-34","MATR3",".",".","mRNA","mRNA",21858232,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0005198,GO:0005634,GO:0005637,GO:0016363","nucleotide binding,RNA binding,protein binding,zinc ion binding,nucleic acid binding,structural molecule activity,nucleus,nuclear inner membrane,nuclear matrix"," MYOPATHY, DISTAL, 2; MPD2"]
["SNRPD1","small nuclear ribonucleoprotein D1 polypeptide 16kDa [Source:HGNC Symbol;Acc:11158]","ENSG00000167088","ENSP00000300413",1,"LSM[1]","family-340","SNRPD1",".",".","snRNA","snRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0030532,GO:0005689,GO:0071013,GO:0016070,GO:0008380,GO:0000398,GO:0000245,GO:0000387,GO:0034660","RNA binding,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005634,GO:0005737,GO:0003723,GO:0005515,GO:0005829,GO:0005654,GO:0030532,GO:0005689,GO:0071013,GO:0010467,GO:0016070,GO:0008380,GO:0000398,GO:0000245,GO:0000387,GO:0034660","nucleus,cytoplasm,RNA binding,protein binding,cytosol,nucleoplasm,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,gene expression,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["SNRPC","small nuclear ribonucleoprotein polypeptide C [Source:HGNC Symbol;Acc:11157]","ENSG00000124562","ENSP00000244520",1,"zf-U1[1]","family-341","SNRPC",".",".","snRNA","snRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0005685,GO:0000398,GO:0000387,GO:0003727,GO:0003729,GO:0071004,GO:0000395","U1 snRNP,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,single-stranded RNA binding,mRNA binding,U2-type prespliceosome,mRNA 5'-splice site recognition","GO:0008270,GO:0003676,GO:0005634,GO:0005685,GO:0000398,GO:0000387,GO:0005515,GO:0042803,GO:0003727,GO:0003729,GO:0015030,GO:0000243,GO:0071004,GO:0000395","zinc ion binding,nucleic acid binding,nucleus,U1 snRNP,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,protein binding,protein homodimerization activity,single-stranded RNA binding,mRNA binding,Cajal body,commitment complex,U2-type prespliceosome,mRNA 5'-splice site recognition","."]
["FXR1","fragile X mental retardation, autosomal homolog 1 [Source:HGNC Symbol;Acc:4023]","ENSG00000114416","ENSP00000420643",4,"Agenet[1],FXR1P_C[1],KH_1[2]","family-342","FMR1,FXR2,FXR1","FMR1","FXR2[51,48],FXR1[54,55]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0002151,GO:0003730","RNA binding,G-quadruplex RNA binding,mRNA 3'-UTR binding","GO:0003723,GO:0002151,GO:0003730,GO:0005634,GO:0005737,GO:0043034,GO:0005844,GO:0017148,GO:0005730,GO:0006915,GO:0030154,GO:0007517,GO:0005515","RNA binding,G-quadruplex RNA binding,mRNA 3'-UTR binding,nucleus,cytoplasm,costamere,polysome,negative regulation of translation,nucleolus,apoptotic process,cell differentiation,muscle organ development,protein binding","."]
["FXR2","fragile X mental retardation, autosomal homolog 2 [Source:HGNC Symbol;Acc:4024]","ENSG00000129245","ENSP00000250113",4,"Agenet[1],FXR1P_C[1],KH_1[2]","family-342","FMR1,FXR2,FXR1","FMR1","FXR2[51,48],FXR1[54,55]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0022625","RNA binding,cytosolic large ribosomal subunit","GO:0003723,GO:0005515,GO:0042802,GO:0005737,GO:0022625","RNA binding,protein binding,identical protein binding,cytoplasm,cytosolic large ribosomal subunit","."]
["FMR1","fragile X mental retardation 1 [Source:HGNC Symbol;Acc:3775]","ENSG00000102081","ENSP00000359506",4,"Agenet[1],FXR1P_C[1],KH_1[2]","family-342","FMR1,FXR2,FXR1","FMR1","FXR2[51,48],FXR1[54,55]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0005845,GO:0010494,GO:0071598,GO:0042788,GO:0051028","RNA binding,mRNA binding,mRNA cap binding complex,cytoplasmic stress granule,neuronal ribonucleoprotein granule,polysomal ribosome,mRNA transport","GO:0003723,GO:0005515,GO:0003729,GO:0005737,GO:0005730,GO:0005654,GO:0043197,GO:0005845,GO:0045202,GO:0043198,GO:0010494,GO:0071598,GO:0042788,GO:0051028,GO:0007417,GO:0045947,GO:0005634,GO:0030425,GO:0043005","RNA binding,protein binding,mRNA binding,cytoplasm,nucleolus,nucleoplasm,dendritic spine,mRNA cap binding complex,synapse,dendritic shaft,cytoplasmic stress granule,neuronal ribonucleoprotein granule,polysomal ribosome,mRNA transport,central nervous system development,negative regulation of translational initiation,nucleus,dendrite,neuron projection"," FRAGILE X TREMOR/ATAXIA SYNDROME; FXTAS"]
["MEPCE","methylphosphate capping enzyme [Source:HGNC Symbol;Acc:20247]","ENSG00000146834","ENSP00000308546",2,"Methyltransf_31[1],Bin3[1]","family-343","MEPCE",".",".","ncRNA","7SK",17643375,"candidate mRNA binder","novel",1,1,".",".","GO:0008173,GO:0001510,GO:0016073,GO:0040031","RNA methyltransferase activity,RNA methylation,snRNA metabolic process,snRNA modification","GO:0008168,GO:0008173,GO:0008757,GO:0000122,GO:0035562,GO:0001510,GO:1900087,GO:0016073,GO:0040031","methyltransferase activity,RNA methyltransferase activity,S-adenosylmethionine-dependent methyltransferase activity,negative regulation of transcription from RNA polymerase II promoter,negative regulation of chromatin binding,RNA methylation,positive regulation of G1/S transition of mitotic cell cycle,snRNA metabolic process,snRNA modification","."]
["KAT8","K(lysine) acetyltransferase 8 [Source:HGNC Symbol;Acc:17933]","ENSG00000103510","ENSP00000406037",2,"Tudor-knot[1],MOZ_SAS[1]","family-344","KAT5,KAT7,KAT6B,KAT8,KAT6A","KAT5","KAT7[32,29],KAT6B[37,10],KAT8[33,38],KAT6A[37,10]","ncRNA","lincRNA",11014199,".",".",".",".",".",".",".",".","GO:0005515,GO:0046872,GO:0035064,GO:0019899,GO:0016747,GO:0008134,GO:0004402,GO:0016407,GO:0043995,GO:0043996,GO:0046972,GO:0000123,GO:0005634,GO:0000776,GO:0071339,GO:0072487,GO:0006351,GO:0045893,GO:0045892,GO:0006355,GO:0016573,GO:0030099,GO:0043984,GO:0043981,GO:0043982","protein binding,metal ion binding,methylated histone residue binding,enzyme binding,transferase activity, transferring acyl groups other than amino-acyl groups,transcription factor binding,histone acetyltransferase activity,acetyltransferase activity,histone acetyltransferase activity (H4-K5 specific),histone acetyltransferase activity (H4-K8 specific),histone acetyltransferase activity (H4-K16 specific),histone acetyltransferase complex,nucleus,kinetochore,MLL1 complex,MSL complex,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,negative regulation of transcription, DNA-dependent,regulation of transcription, DNA-dependent,histone acetylation,myeloid cell differentiation,histone H4-K16 acetylation,histone H4-K5 acetylation,histone H4-K8 acetylation","."]
["CIRBP","cold inducible RNA binding protein [Source:HGNC Symbol;Acc:1982]","ENSG00000099622","ENSP00000465558",1,"RRM_1[1]","family-345","CIRBP,RBM3","CIRBP","RBM3[63,69]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0030371,GO:0010494,GO:0003730,GO:0070181,GO:0045727,GO:0048255","translation repressor activity,cytoplasmic stress granule,mRNA 3'-UTR binding,SSU rRNA binding,positive regulation of translation,mRNA stabilization","GO:0000166,GO:0003676,GO:0030371,GO:0010494,GO:0009409,GO:0034063,GO:0005515,GO:0003730,GO:0070181,GO:0005634,GO:0005737,GO:0005654,GO:0045727,GO:0009411,GO:0048255,GO:0017148","nucleotide binding,nucleic acid binding,translation repressor activity,cytoplasmic stress granule,response to cold,stress granule assembly,protein binding,mRNA 3'-UTR binding,SSU rRNA binding,nucleus,cytoplasm,nucleoplasm,positive regulation of translation,response to UV,mRNA stabilization,negative regulation of translation","."]
["RBM3","RNA binding motif (RNP1, RRM) protein 3 [Source:HGNC Symbol;Acc:9900]","ENSG00000102317","ENSP00000365950",1,"RRM_1[1]","family-345","CIRBP,RBM3","CIRBP","RBM3[63,69]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0043023,GO:0015934,GO:0006412,GO:0006417,GO:0006396,GO:0045727,GO:0035196","RNA binding,ribosomal large subunit binding,large ribosomal subunit,translation,regulation of translation,RNA processing,positive regulation of translation,production of miRNAs involved in gene silencing by miRNA","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0043023,GO:0005634,GO:0005737,GO:0030425,GO:0015934,GO:0006412,GO:0006417,GO:0006396,GO:0009409,GO:0045727,GO:0035196","nucleotide binding,RNA binding,protein binding,nucleic acid binding,ribosomal large subunit binding,nucleus,cytoplasm,dendrite,large ribosomal subunit,translation,regulation of translation,RNA processing,response to cold,positive regulation of translation,production of miRNAs involved in gene silencing by miRNA","."]
["CNOT7","CCR4-NOT transcription complex, subunit 7 [Source:HGNC Symbol;Acc:14101]","ENSG00000198791","ENSP00000430160",1,"CAF1[1]","family-346","CNOT7,CNOT8","CNOT7","CNOT8[76,74]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0004535,GO:0000932,GO:0000289,GO:0031047,GO:0000290,GO:0033962,GO:0003723,GO:0000175,GO:0004532,GO:0016070,GO:0016071,GO:0000288,GO:0006417,GO:0060213,GO:1900153,GO:0035195,GO:0043928","poly(A)-specific ribonuclease activity,cytoplasmic mRNA processing body,nuclear-transcribed mRNA poly(A) tail shortening,gene silencing by RNA,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly,RNA binding,3'-5'-exoribonuclease activity,exoribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of translation,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003676,GO:0004535,GO:0005634,GO:0000932,GO:0030014,GO:0006351,GO:0045944,GO:0000289,GO:0031047,GO:0000290,GO:0033962,GO:0003723,GO:0003700,GO:0005515,GO:0046872,GO:0004871,GO:0000175,GO:0004532,GO:0005829,GO:0008285,GO:0008284,GO:0007165,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006417,GO:0060213,GO:1900153,GO:0005975,GO:0035195,GO:0043928,GO:0005737","nucleic acid binding,poly(A)-specific ribonuclease activity,nucleus,cytoplasmic mRNA processing body,CCR4-NOT complex,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,nuclear-transcribed mRNA poly(A) tail shortening,gene silencing by RNA,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly,RNA binding,sequence-specific DNA binding transcription factor activity,protein binding,metal ion binding,signal transducer activity,3'-5'-exoribonuclease activity,exoribonuclease activity,cytosol,negative regulation of cell proliferation,positive regulation of cell proliferation,signal transduction,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of translation,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,carbohydrate metabolic process,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,cytoplasm","."]
["CNOT8","CCR4-NOT transcription complex, subunit 8 [Source:HGNC Symbol;Acc:9207]","ENSG00000155508","ENSP00000430493",1,"CAF1[1]","family-346","CNOT7,CNOT8","CNOT7","CNOT8[76,74]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004535,GO:0000175,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0035195,GO:0043928","RNA binding,poly(A)-specific ribonuclease activity,3'-5'-exoribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003676,GO:0005634,GO:0006351,GO:0003723,GO:0003700,GO:0005515,GO:0046872,GO:0004535,GO:0000175,GO:0005829,GO:0005622,GO:0030014,GO:0008285,GO:0006355,GO:0008284,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0035195,GO:0043928","nucleic acid binding,nucleus,transcription, DNA-templated,RNA binding,sequence-specific DNA binding transcription factor activity,protein binding,metal ion binding,poly(A)-specific ribonuclease activity,3'-5'-exoribonuclease activity,cytosol,intracellular,CCR4-NOT complex,negative regulation of cell proliferation,regulation of transcription, DNA-dependent,positive regulation of cell proliferation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["A1CF","APOBEC1 complementation factor [Source:HGNC Symbol;Acc:24086]","ENSG00000148584","ENSP00000282641",4,"RRM_1[2],DND1_DSRM[1],RRM_6[1]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","mRNA",10669759,".",".",".",".",".",1,"GO:0003723,GO:0003727,GO:0030895,GO:0006397,GO:0016556","RNA binding,single-stranded RNA binding,apolipoprotein B mRNA editing enzyme complex,mRNA processing,mRNA modification","GO:0000166,GO:0003676,GO:0005737,GO:0003723,GO:0005515,GO:0003727,GO:0005783,GO:0005654,GO:0030895,GO:0010467,GO:0006397,GO:0050821,GO:0016554,GO:0016556","nucleotide binding,nucleic acid binding,cytoplasm,RNA binding,protein binding,single-stranded RNA binding,endoplasmic reticulum,nucleoplasm,apolipoprotein B mRNA editing enzyme complex,gene expression,mRNA processing,protein stabilization,cytidine to uridine editing,mRNA modification","."]
["RBM46","RNA binding motif protein 46 [Source:HGNC Symbol;Acc:28401]","ENSG00000151962","ENSP00000424500",4,"RRM_1[3],DND1_DSRM[1]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723","nucleotide binding,nucleic acid binding,RNA binding","."]
["RBM47","RNA binding motif protein 47 [Source:HGNC Symbol;Acc:30358]","ENSG00000163694","ENSP00000423243",3,"RRM_1[3]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005634","nucleotide binding,RNA binding,nucleic acid binding,nucleus","."]
["DND1","dead end homolog 1 (zebrafish) [Source:HGNC Symbol;Acc:23799]","ENSG00000256453","ENSP00000445366",2,"RRM_1[1],DND1_DSRM[1]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0017091,GO:0060965","AU-rich element binding,negative regulation of gene silencing by miRNA","GO:0005515,GO:0000166,GO:0003676,GO:0017091,GO:0005634,GO:0005737,GO:0007275,GO:0007281,GO:0060965","protein binding,nucleotide binding,nucleic acid binding,AU-rich element binding,nucleus,cytoplasm,multicellular organismal development,germ cell development,negative regulation of gene silencing by miRNA","."]
["HNRNPR","heterogeneous nuclear ribonucleoprotein R [Source:HGNC Symbol;Acc:5047]","ENSG00000125944","ENSP00000363741",3,"RRM_1[3]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005681,GO:0030529,GO:0071013,GO:0006397,GO:0008380,GO:0000398","RNA binding,spliceosomal complex,ribonucleoprotein complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005654,GO:0005681,GO:0030529,GO:0019013,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398","nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleus,cytoplasm,nucleoplasm,spliceosomal complex,ribonucleoprotein complex,viral nucleocapsid,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","."]
["SYNCRIP","synaptotagmin binding, cytoplasmic RNA interacting protein [Source:HGNC Symbol;Acc:16918]","ENSG00000135316","ENSP00000358635",3,"RRM_1[3]","family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","A1CF","RBM47[46,46],DND1[19,32],RBM46[44,49],SYNCRIP[31,30],HNRNPR[32,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0008143,GO:0071204,GO:0003723,GO:0030529,GO:0071013,GO:0070937,GO:0008380,GO:0000398,GO:0006396,GO:0070934","poly(A) RNA binding,histone pre-mRNA 3'end processing complex,RNA binding,ribonucleoprotein complex,catalytic step 2 spliceosome,CRD-mediated mRNA stability complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing,CRD-mediated mRNA stabilization","GO:0008143,GO:0005737,GO:0071204,GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005783,GO:0005654,GO:0030529,GO:0071013,GO:0070937,GO:0097452,GO:0008380,GO:0000398,GO:0006396,GO:0071346,GO:0017148,GO:0019048,GO:0070934","poly(A) RNA binding,cytoplasm,histone pre-mRNA 3'end processing complex,nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,endoplasmic reticulum,nucleoplasm,ribonucleoprotein complex,catalytic step 2 spliceosome,CRD-mediated mRNA stability complex,GAIT complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing,cellular response to interferon-gamma,negative regulation of translation,modulation by virus of host morphology or physiology,CRD-mediated mRNA stabilization","."]
["ABCE1","ATP-binding cassette, sub-family E (OABP), member 1 [Source:HGNC Symbol;Acc:69]","ENSG00000164163","ENSP00000296577",4,"Fer4[1],RLI[1],ABC_tran[2]","family-348","ABCE1",".",".","ncRNA","putative viral RNA","Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0008428,GO:0006401","ribonuclease inhibitor activity,RNA catabolic process","GO:0005524,GO:0016887,GO:0000166,GO:0017111,GO:0051536,GO:0008428,GO:0005737,GO:0005739,GO:0009615,GO:0019048,GO:0006401","ATP binding,ATPase activity,nucleotide binding,nucleoside-triphosphatase activity,iron-sulfur cluster binding,ribonuclease inhibitor activity,cytoplasm,mitochondrion,response to virus,modulation by virus of host morphology or physiology,RNA catabolic process","."]
["GPATCH4","G patch domain containing 4 [Source:HGNC Symbol;Acc:25982]","ENSG00000160818","ENSP00000412620",1,"G-patch[1]","family-349","GPATCH4",".",".","unknown","unknown","established RBP ",".","novel",".",1,".",".",".",".","GO:0003676","nucleic acid binding","."]
["PAIP1","poly(A) binding protein interacting protein 1 [Source:HGNC Symbol;Acc:16945]","ENSG00000172239","ENSP00000425675",2,"PAM2[1],MIF4G[1]","family-35","PAIP1",".",".","mRNA","mRNA","The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0008494,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0045727,GO:0048255,GO:0006413","RNA binding,translation activator activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of translation,mRNA stabilization,translational initiation","GO:0005488,GO:0003723,GO:0005515,GO:0008494,GO:0005737,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0045727,GO:0048255,GO:0006413","binding,RNA binding,protein binding,translation activator activity,cytoplasm,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of translation,mRNA stabilization,translational initiation","."]
["RBM20","RNA binding motif protein 20 [Source:HGNC Symbol;Acc:27424]","ENSG00000203867","ENSP00000358532",1,"RRM_5[1]","family-350","RBM20",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0033120,GO:0006397,GO:0008380","RNA binding,positive regulation of RNA splicing,mRNA processing,RNA splicing","GO:0003723,GO:0000166,GO:0008270,GO:0003676,GO:0005634,GO:0007507,GO:0033120,GO:0006397,GO:0008380","RNA binding,nucleotide binding,zinc ion binding,nucleic acid binding,nucleus,heart development,positive regulation of RNA splicing,mRNA processing,RNA splicing"," CARDIOMYOPATHY, DILATED, 1DD; CMD1DD"]
["GNL3","guanine nucleotide binding protein-like 3 (nucleolar) [Source:HGNC Symbol;Acc:29931]","ENSG00000163938","ENSP00000378278",3,"MMR_HSR1[1],GN3L_Grn1[1],GTP_EFTU[1]","family-351","GNL3,GNL3L","GNL3","GNL3L[31,29]","rRNA","putative rRNA","NUG1 yeast homolog","candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005525,GO:0005730,GO:0005654,GO:0008283,GO:0042127,GO:0005515,GO:0003924,GO:0005634,GO:0042254,GO:0006184","GTP binding,nucleolus,nucleoplasm,cell proliferation,regulation of cell proliferation,protein binding,GTPase activity,nucleus,ribosome biogenesis,GTP catabolic process","."]
["GNL3L","guanine nucleotide binding protein-like 3 (nucleolar)-like [Source:HGNC Symbol;Acc:25553]","ENSG00000130119","ENSP00000338573",2,"MMR_HSR1[1],GTP_EFTU[1]","family-351","GNL3,GNL3L","GNL3","GNL3L[31,29]","rRNA","putative rRNA","NUG1 yeast homolog",".","novel",".",1,1,".","GO:0042254","ribosome biogenesis","GO:0005515,GO:0005525,GO:0003924,GO:0015093,GO:0016021,GO:0005634,GO:0005739,GO:0005730,GO:0042254,GO:0006184,GO:0015684","protein binding,GTP binding,GTPase activity,ferrous iron transmembrane transporter activity,integral to membrane,nucleus,mitochondrion,nucleolus,ribosome biogenesis,GTP catabolic process,ferrous iron transport","."]
["FAM120A","family with sequence similarity 120A [Source:HGNC Symbol;Acc:13247]","ENSG00000048828","ENSP00000277165",".",".","family-352","FAM120A,FAM120C,FAM120B","FAM120A","FAM120C[54,56],FAM120B[18,22]","mRNA","mRNA",19015244,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723","RNA binding","GO:0003723,GO:0005886,GO:0005737","RNA binding,plasma membrane,cytoplasm","."]
["FAM120B","family with sequence similarity 120B [Source:HGNC Symbol;Acc:21109]","ENSG00000112584","ENSP00000417970",2,"DUF4655[1],XPG_I_2[1]","family-352","FAM120A,FAM120C,FAM120B","FAM120A","FAM120C[54,56],FAM120B[18,22]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0005634,GO:0006351,GO:0030154,GO:0006355","nucleus,transcription, DNA-templated,cell differentiation,regulation of transcription, DNA-dependent","."]
["FAM120C","family with sequence similarity 120C [Source:HGNC Symbol;Acc:16949]","ENSG00000184083","ENSP00000364324",".",".","family-352","FAM120A,FAM120C,FAM120B","FAM120A","FAM120C[54,56],FAM120B[18,22]","unknown","unknown","established RBP ","candidate mRNA binder","novel",1,1,".",".",".",".",".",".","."]
["KHDC1","KH homology domain containing 1 [Source:HGNC Symbol;Acc:21366] [Type: protein coding Ensembl/Havana merge]","ENSG00000135314","ENSP00000359411",".",".","family-353","KHDC1,KHDC1L","KHDC1","KHDC1L[46,84]","mRNA","mRNA",22731819,".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0016021","RNA binding,integral to membrane","."]
["KHDC1L","Putative KHDC1-like protein [Source:UniProtKB/TrEMBL;Acc:F5H697] [Type: protein coding Havana]","ENSG00000243501","ENSP00000359415",".",".","family-353","KHDC1,KHDC1L","KHDC1","KHDC1L[46,84]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["RPL10L","ribosomal protein L10-like [Source:HGNC Symbol;Acc:17976]","ENSG00000165496","ENSP00000298283",1,"Ribosomal_L16[1]","family-354","RPL10,RPL10L","RPL10","RPL10L[94,94]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0022625,GO:0006412","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation","GO:0003735,GO:0005634,GO:0005622,GO:0005840,GO:0022625,GO:0007283,GO:0006412","structural constituent of ribosome,nucleus,intracellular,ribosome,cytosolic large ribosomal subunit,spermatogenesis,translation","."]
["RPL10","ribosomal protein L10 [Source:HGNC Symbol;Acc:10298]","ENSG00000147403","ENSP00000341730",1,"Ribosomal_L16[1]","family-354","RPL10,RPL10L","RPL10","RPL10L[94,94]","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0003735,GO:0005829,GO:0005622,GO:0005783,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","protein binding,structural constituent of ribosome,cytosol,intracellular,endoplasmic reticulum,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription"," AUTISM, SUSCEPTIBILITY TO, X-LINKED 5; AUTSX5"]
["EIF2S1","eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa [Source:HGNC Symbol;Acc:3265]","ENSG00000134001","ENSP00000256383",2,"S1[1],EIF_2_alpha[1]","family-355","EIF2S1",".",".","tRNA","tRNA","The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]","translationfactor","RNAbinding",1,1,1,1,"GO:0003723,GO:0003743,GO:0005850,GO:0043022,GO:0010494,GO:0005851,GO:0006412,GO:0043558,GO:0006413","RNA binding,translation initiation factor activity,eukaryotic translation initiation factor 2 complex,ribosome binding,cytoplasmic stress granule,eukaryotic translation initiation factor 2B complex,translation,regulation of translational initiation in response to stress,translational initiation","GO:0003723,GO:0003743,GO:0005850,GO:0005515,GO:0043022,GO:0005634,GO:0005829,GO:0010494,GO:0005844,GO:0005851,GO:0006412,GO:0010467,GO:0046777,GO:0044267,GO:0030968,GO:0043558,GO:0006413,GO:0006987,GO:0005737","RNA binding,translation initiation factor activity,eukaryotic translation initiation factor 2 complex,protein binding,ribosome binding,nucleus,cytosol,cytoplasmic stress granule,polysome,eukaryotic translation initiation factor 2B complex,translation,gene expression,protein autophosphorylation,cellular protein metabolic process,endoplasmic reticulum unfolded protein response,regulation of translational initiation in response to stress,translational initiation,activation of signaling protein activity involved in unfolded protein response,cytoplasm","."]
["MRPL20","mitochondrial ribosomal protein L20 [Source:HGNC Symbol;Acc:14478]","ENSG00000242485","ENSP00000341082",1,"Ribosomal_L20[1]","family-356","MRPL20",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0019843,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,rRNA binding,ribosome,translation,mitochondrial ribosome","GO:0003735,GO:0019843,GO:0005622,GO:0005840,GO:0006412,GO:0005515,GO:0005739,GO:0005761","structural constituent of ribosome,rRNA binding,intracellular,ribosome,translation,protein binding,mitochondrion,mitochondrial ribosome","."]
["EPRS","glutamyl-prolyl-tRNA synthetase [Source:HGNC Symbol;Acc:3418]","ENSG00000136628","ENSP00000355890",9,"tRNA-synt_2b[1],GST_C_3[1],ProRS-C_1[1],tRNA-synt_1c[1],HGTP_anticodon[1],tRNA-synt_1c_C[1],WHEP-TRS[3]","family-357","EPRS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0016876,GO:0004818,GO:0006412,GO:0006418,GO:0043039,GO:0006424,GO:0035613,GO:0004827,GO:0030529,GO:0006433","aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,glutamate-tRNA ligase activity,translation,tRNA aminoacylation for protein translation,tRNA aminoacylation,glutamyl-tRNA aminoacylation,RNA stem-loop binding,proline-tRNA ligase activity,ribonucleoprotein complex,prolyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0016876,GO:0004818,GO:0005737,GO:0006412,GO:0006418,GO:0043039,GO:0006424,GO:0005515,GO:0035613,GO:0004827,GO:0005829,GO:0030529,GO:0097452,GO:0017148,GO:0071346,GO:0010467,GO:0006461,GO:0006433","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,glutamate-tRNA ligase activity,cytoplasm,translation,tRNA aminoacylation for protein translation,tRNA aminoacylation,glutamyl-tRNA aminoacylation,protein binding,RNA stem-loop binding,proline-tRNA ligase activity,cytosol,ribonucleoprotein complex,GAIT complex,negative regulation of translation,cellular response to interferon-gamma,gene expression,protein complex assembly,prolyl-tRNA aminoacylation","."]
["DHX58","DEXH (Asp-Glu-X-His) box polypeptide 58 [Source:HGNC Symbol;Acc:29517]","ENSG00000260178","ENSP00000455290",3,"Helicase_C[1],ResIII[1],RIG-I_C-RD[1]","family-358","DDX58,IFIH1,DHX58","DDX58","IFIH1[33,29],DHX58[22,30]","ncRNA","viral RNA",18411269,".",".",".",".",".",".","GO:0003725,GO:0003727","double-stranded RNA binding,single-stranded RNA binding","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0005737,GO:0009615,GO:0032480,GO:0045824,GO:0032481,GO:0039536,GO:1900245,GO:1900246,GO:0005515,GO:0008270,GO:0016817,GO:0003725,GO:0003727,GO:0004386,GO:0045087,GO:0051607,GO:0019048,GO:0045088,GO:0039534","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,cytoplasm,response to virus,negative regulation of type I interferon production,negative regulation of innate immune response,positive regulation of type I interferon production,negative regulation of RIG-I signaling pathway,positive regulation of MDA-5 signaling pathway,positive regulation of RIG-I signaling pathway,protein binding,zinc ion binding,hydrolase activity, acting on acid anhydrides,double-stranded RNA binding,single-stranded RNA binding,helicase activity,innate immune response,defense response to virus,modulation by virus of host morphology or physiology,regulation of innate immune response,negative regulation of MDA-5 signaling pathway","."]
["DDX58","DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 [Source:HGNC Symbol;Acc:19102]","ENSG00000107201","ENSP00000369213",3,"Helicase_C[1],RIG-I_C-RD[1],DEAD[1]","family-358","DDX58,IFIH1,DHX58","DDX58","IFIH1[33,29],DHX58[22,30]","ncRNA","ncRNA"," RIG-I, established RBP ",".",".",".",".",".",".","GO:0003725,GO:0003727,GO:0043330,GO:0039529","double-stranded RNA binding,single-stranded RNA binding,response to exogenous dsRNA,RIG-I signaling pathway","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0004386,GO:0016817,GO:0003690,GO:0003725,GO:0003727,GO:0045087,GO:0009615,GO:0032728,GO:0043330,GO:0005515,GO:0008270,GO:0042802,GO:0005737,GO:0005923,GO:0005829,GO:0015629,GO:0032587,GO:0045944,GO:0032480,GO:0002230,GO:0030334,GO:0051091,GO:0032727,GO:0019048,GO:0009597,GO:0034344,GO:0039528,GO:0039529,GO:0042993","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,hydrolase activity, acting on acid anhydrides,double-stranded DNA binding,double-stranded RNA binding,single-stranded RNA binding,innate immune response,response to virus,positive regulation of interferon-beta production,response to exogenous dsRNA,protein binding,zinc ion binding,identical protein binding,cytoplasm,tight junction,cytosol,actin cytoskeleton,ruffle membrane,positive regulation of transcription from RNA polymerase II promoter,negative regulation of type I interferon production,positive regulation of defense response to virus by host,regulation of cell migration,positive regulation of sequence-specific DNA binding transcription factor activity,positive regulation of interferon-alpha production,modulation by virus of host morphology or physiology,detection of virus,regulation of type III interferon production,cytoplasmic pattern recognition receptor signaling pathway in response to virus,RIG-I signaling pathway,positive regulation of transcription factor import into nucleus","."]
["IFIH1","interferon induced with helicase C domain 1 [Source:HGNC Symbol;Acc:18873]","ENSG00000115267","ENSP00000263642",4,"Helicase_C[1],ResIII[1],RIG-I_C-RD[1],CARD[1]","family-358","DDX58,IFIH1,DHX58","DDX58","IFIH1[33,29],DHX58[22,30]","ncRNA","viral RNA","MDA5  23273991",".",".",".",".",".",".","GO:0003725,GO:0003727,GO:0043021","double-stranded RNA binding,single-stranded RNA binding,ribonucleoprotein complex binding","GO:0005515,GO:0008270,GO:0005524,GO:0003677,GO:0003725,GO:0003727,GO:0004386,GO:0043021,GO:0005634,GO:0005737,GO:0005829,GO:0005622,GO:0045087,GO:0042981,GO:0009615,GO:0032728,GO:0032480,GO:0016925,GO:0032727,GO:0019048,GO:0009597,GO:0034344,GO:0039528,GO:0005488,GO:0003676,GO:0016817,GO:0008026,GO:0016787","protein binding,zinc ion binding,ATP binding,DNA binding,double-stranded RNA binding,single-stranded RNA binding,helicase activity,ribonucleoprotein complex binding,nucleus,cytoplasm,cytosol,intracellular,innate immune response,regulation of apoptotic process,response to virus,positive regulation of interferon-beta production,negative regulation of type I interferon production,protein sumoylation,positive regulation of interferon-alpha production,modulation by virus of host morphology or physiology,detection of virus,regulation of type III interferon production,cytoplasmic pattern recognition receptor signaling pathway in response to virus,binding,nucleic acid binding,hydrolase activity, acting on acid anhydrides,ATP-dependent helicase activity,hydrolase activity"," DIABETES MELLITUS, INSULIN-DEPENDENT, 19; IDDM19"]
["CDK5RAP1","CDK5 regulatory subunit associated protein 1 [Source:HGNC Symbol;Acc:15880]","ENSG00000101391","ENSP00000217372",3,"Radical_SAM[1],UPF0004[1],TRAM[1]","family-359","CDK5RAP1,CDKAL1","CDK5RAP1","CDKAL1[21,21]","tRNA","putative tRNA","This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013",".",".",".",".",".",".","GO:0006400,GO:0009451","tRNA modification,RNA modification","GO:0046872,GO:0016740,GO:0051539,GO:0003824,GO:0019901,GO:0032403,GO:0051536,GO:0005737,GO:0043412,GO:0007420,GO:0045736,GO:0006400,GO:0009451,GO:0045664,GO:0000079","metal ion binding,transferase activity,4 iron, 4 sulfur cluster binding,catalytic activity,protein kinase binding,protein complex binding,iron-sulfur cluster binding,cytoplasm,macromolecule modification,brain development,negative regulation of cyclin-dependent protein serine/threonine kinase activity,tRNA modification,RNA modification,regulation of neuron differentiation,regulation of cyclin-dependent protein serine/threonine kinase activity","."]
["HABP4","hyaluronan binding protein 4 [Source:HGNC Symbol;Acc:17062]","ENSG00000130956","ENSP00000364398",1,"HABP4_PAI-RBP1[1]","family-36","HABP4,SERBP1","HABP4","SERBP1[39,40]","mRNA","mRNA",20436279,".",".",".",".",".",".",".",".","GO:0005515,GO:0030017,GO:0005634,GO:0005737,GO:0005576,GO:0005829,GO:0071260,GO:0006351,GO:0006355,GO:0007596,GO:0030168,GO:0043392,GO:0002576","protein binding,sarcomere,nucleus,cytoplasm,extracellular region,cytosol,cellular response to mechanical stimulus,transcription, DNA-templated,regulation of transcription, DNA-dependent,blood coagulation,platelet activation,negative regulation of DNA binding,platelet degranulation","."]
["SERBP1","SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:17860]","ENSG00000142864","ENSP00000360029",1,"HABP4_PAI-RBP1[1]","family-36","HABP4,SERBP1","HABP4","SERBP1[39,40]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,".","GO:0003730,GO:0043488","mRNA 3'-UTR binding,regulation of mRNA stability","GO:0005515,GO:0003730,GO:0005634,GO:0005886,GO:0005737,GO:0048471,GO:0043488,GO:0042981","protein binding,mRNA 3'-UTR binding,nucleus,plasma membrane,cytoplasm,perinuclear region of cytoplasm,regulation of mRNA stability,regulation of apoptotic process","."]
["METTL5","methyltransferase like 5 [Source:HGNC Symbol;Acc:25006] [Type: protein coding Ensembl/Havana merge]","ENSG00000138382","ENSP00000260953",1,"MTS[1]","family-360","METTL5",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".","GO:0001510,GO:0009452,GO:0031167","RNA methylation,7-methylguanosine RNA capping,rRNA methylation","GO:0003676,GO:0008168,GO:0008276,GO:0005737,GO:0008152,GO:0006479,GO:0001510,GO:0009452,GO:0031167","nucleic acid binding,methyltransferase activity,protein methyltransferase activity,cytoplasm,metabolic process,protein methylation,RNA methylation,7-methylguanosine RNA capping,rRNA methylation","."]
["ZCCHC7","zinc finger, CCHC domain containing 7 [Source:HGNC Symbol;Acc:26209]","ENSG00000147905","ENSP00000337839",1,"zf-CCHC[1]","family-361","ZCCHC7",".",".","diverse","diverse",21878619,".","novel",".",1,".",".",".",".","GO:0008270,GO:0003676,GO:0005737,GO:0005730,GO:0005634","zinc ion binding,nucleic acid binding,cytoplasm,nucleolus,nucleus","."]
["WDR36","WD repeat domain 36 [Source:HGNC Symbol;Acc:30696]","ENSG00000134987","ENSP00000424628",2,"Utp21[1],WD40[1]","family-362","WDR36",".",".","rRNA","U3 snoRNA/ rRNA","UTP21yeast homolog,  U3 small nucleolar RNA-associated protein 21",".","RNArelated",".",1,1,".","GO:0006364","rRNA processing","GO:0005515,GO:0001895,GO:0030516,GO:0005730,GO:0032040,GO:0007601,GO:0050896,GO:0006364","protein binding,retina homeostasis,regulation of axon extension,nucleolus,small-subunit processome,visual perception,response to stimulus,rRNA processing"," GLAUCOMA 1, OPEN ANGLE, G; GLC1G"]
["CCDC86","coiled-coil domain containing 86 [Source:HGNC Symbol;Acc:28359]","ENSG00000110104","ENSP00000227520",1,"Cgr1[1]","family-363","CCDC86",".",".","unknown","unknown","established RBP ","candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005634,GO:0005730,GO:0019048","nucleus,nucleolus,modulation by virus of host morphology or physiology","."]
["C2orf15","chromosome 2 open reading frame 15 [Source:HGNC Symbol;Acc:28436]","ENSG00000241962","ENSP00000420959",1,"Ribosomal_L30[1]","family-364","C2orf15,MRPL30,MRPL30","C2orf15","MRPL30[100,100],MRPL30[74,91]","rRNA","putative rRNA","by homology","ribosomal",".",".",1,".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["MRPL30","mitochondrial ribosomal protein L30 [Source:HGNC Symbol;Acc:14036]","ENSG00000185414","ENSP00000386970",1,"Ribosomal_L30[1]","family-364","C2orf15,MRPL30,MRPL30","C2orf15","MRPL30[100,100],MRPL30[74,91]","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["RPS26","ribosomal protein S26 [Source:HGNC Symbol;Acc:10414]","ENSG00000197728","ENSP00000348849",1,"Ribosomal_S26e[1]","family-365","RPS26",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0003729,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0033119,GO:0006415","structural constituent of ribosome,mRNA binding,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of RNA splicing,translational termination","GO:0005515,GO:0003735,GO:0003729,GO:0005829,GO:0005622,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0033119,GO:0006415,GO:0019083","protein binding,structural constituent of ribosome,mRNA binding,cytosol,intracellular,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of RNA splicing,translational termination,viral transcription"," DIAMOND-BLACKFAN ANEMIA 10; DBA10"]
["TEX13A","testis expressed 13A [Source:HGNC Symbol;Acc:11735]","ENSG00000133149","ENSP00000399753",2,"zf-RanBP[1],TEX13[1]","family-366","TEX13A,TEX13B","TEX13A","TEX13B[41,54]","mRNA","putative mRNA",21256132,".",".",".",".",".",".",".",".","GO:0008270","zinc ion binding","."]
["BARD1","BRCA1 associated RING domain 1 [Source:HGNC Symbol;Acc:952]","ENSG00000138376","ENSP00000260947",5,"BRCT[2],Ank_2[1],Ank[1],zf-RING_6[1]","family-367","BARD1",".",".","ncRNA","lincRNA",12419249,".",".",".",".",".",".","GO:0003723,GO:0070531,GO:0031436,GO:0031441","RNA binding,BRCA1-A complex,BRCA1-BARD1 complex,negative regulation of mRNA 3'-end processing","GO:0005515,GO:0003723,GO:0042803,GO:0008270,GO:0019900,GO:0004842,GO:0046982,GO:0005634,GO:0005737,GO:0000151,GO:0070531,GO:0031436,GO:0016567,GO:0043066,GO:0006974,GO:0006281,GO:0043065,GO:0007050,GO:0001894,GO:0045732,GO:0042325,GO:0085020,GO:0046826,GO:0031441","protein binding,RNA binding,protein homodimerization activity,zinc ion binding,kinase binding,ubiquitin-protein ligase activity,protein heterodimerization activity,nucleus,cytoplasm,ubiquitin ligase complex,BRCA1-A complex,BRCA1-BARD1 complex,protein ubiquitination,negative regulation of apoptotic process,cellular response to DNA damage stimulus,DNA repair,positive regulation of apoptotic process,cell cycle arrest,tissue homeostasis,positive regulation of protein catabolic process,regulation of phosphorylation,protein K6-linked ubiquitination,negative regulation of protein export from nucleus,negative regulation of mRNA 3'-end processing","."]
["XPO4","exportin 4 [Source:HGNC Symbol;Acc:17796]","ENSG00000132953","ENSP00000383444",1,"CRM1_C[1]","family-368","XPO4",".",".","mRNA","mRBP transport",10944119,".",".",".",".",".",".",".",".","GO:0005488,GO:0005515,GO:0005634,GO:0005737,GO:0015031,GO:0046827","binding,protein binding,nucleus,cytoplasm,protein transport,positive regulation of protein export from nucleus","."]
["RUVBL1","RuvB-like 1 (E. coli) [Source:HGNC Symbol;Acc:10474] [Type: protein coding Ensembl/Havana merge]","ENSG00000175792","ENSP00000318297",1,"TIP49[1]","family-369","RUVBL1",".",".","mRNA","mRNA",20371770,".",".",".",".",".",".",".",".","GO:0000166,GO:0005515,GO:0005524,GO:0017111,GO:0003678,GO:0009378,GO:0005634,GO:0005737,GO:0016020,GO:0043231,GO:0005794,GO:0005654,GO:0005815,GO:0016363,GO:0031011,GO:0071339,GO:0035267,GO:0006351,GO:0007067,GO:0007283,GO:0006281,GO:0006310,GO:0006334,GO:0040008,GO:0006357,GO:0034080,GO:0032508,GO:0043967,GO:0043968,GO:0043141,GO:0043234","nucleotide binding,protein binding,ATP binding,nucleoside-triphosphatase activity,DNA helicase activity,four-way junction helicase activity,nucleus,cytoplasm,membrane,intracellular membrane-bounded organelle,Golgi apparatus,nucleoplasm,microtubule organizing center,nuclear matrix,Ino80 complex,MLL1 complex,NuA4 histone acetyltransferase complex,transcription, DNA-templated,mitosis,spermatogenesis,DNA repair,DNA recombination,nucleosome assembly,regulation of growth,regulation of transcription from RNA polymerase II promoter,CENP-A containing nucleosome assembly at centromere,DNA duplex unwinding,histone H4 acetylation,histone H2A acetylation,ATP-dependent 5'-3' DNA helicase activity,protein complex","."]
["IMP4","IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) [Source:HGNC Symbol;Acc:30856]","ENSG00000136718","ENSP00000389701",1,"Brix[1]","family-37","IMP4",".",".","snoRNA","snoRNA","IMP4 forms a ternary complex with IMP3 (MIM 612980) and MPP10 (MPHOSPHO10; MIM 605503) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing (Granneman et al., 2003 [PubMed 12655004]).[supplied by OMIM, Aug 2009]",".",".",".",".",1,".","GO:0030529,GO:0006364","ribonucleoprotein complex,rRNA processing","GO:0005515,GO:0005730,GO:0030529,GO:0006364","protein binding,nucleolus,ribonucleoprotein complex,rRNA processing","."]
["DDX52","DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 [Source:HGNC Symbol;Acc:20038]","ENSG00000141141","ENSP00000377893",2,"Helicase_C[1],DEAD[1]","family-370","DDX52",".",".","rRNA","putative rRNA","ROK1 yeast homolog","helicase","RNAbinding",1,1,1,".","GO:0003723","RNA binding","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0004386,GO:0003723,GO:0005730","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,RNA binding,nucleolus","."]
["THOC1","THO complex 1 [Source:HGNC Symbol;Acc:19070]","ENSG00000079134","ENSP00000261600",2,"efThoc1[1],Death[1]","family-371","THOC1",".",".","mRNA","mRNA",17190602,".",".",".",".",".",".","GO:0003723,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0006396,GO:0006406","RNA binding,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,RNA processing,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0003677,GO:0005634,GO:0005737,GO:0016363,GO:0016607,GO:0000346,GO:0000347,GO:0000445,GO:0006351,GO:0006915,GO:0007165,GO:0006397,GO:0008380,GO:0006396,GO:0031297,GO:0006406,GO:0032784,GO:0032786,GO:2000002,GO:0000018,GO:0046784,GO:0048297","RNA binding,protein binding,DNA binding,nucleus,cytoplasm,nuclear matrix,nuclear speck,transcription export complex,THO complex,THO complex part of transcription export complex,transcription, DNA-templated,apoptotic process,signal transduction,mRNA processing,RNA splicing,RNA processing,replication fork processing,mRNA export from nucleus,regulation of DNA-dependent transcription, elongation,positive regulation of DNA-dependent transcription, elongation,negative regulation of DNA damage checkpoint,regulation of DNA recombination,viral mRNA export from host cell nucleus,negative regulation of isotype switching to IgA isotypes","."]
["TRPT1","tRNA phosphotransferase 1 [Source:HGNC Symbol;Acc:20316]","ENSG00000149743","ENSP00000439586",1,"PTS_2-RNA[1]","family-372","TRPT1",".",".","tRNA","tRNA",14504659,".",".",".",".",".",".","GO:0000215,GO:0006388","tRNA 2'-phosphotransferase activity,tRNA splicing, via endonucleolytic cleavage and ligation","GO:0016772,GO:0000215,GO:0006388,GO:0045859,GO:0008665","transferase activity, transferring phosphorus-containing groups,tRNA 2'-phosphotransferase activity,tRNA splicing, via endonucleolytic cleavage and ligation,regulation of protein kinase activity,2'-phosphotransferase activity","."]
["NHP2L1","NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:7819]","ENSG00000100138","ENSP00000383989",1,"Ribosomal_L7Ae[1]","family-373","NHP2L1",".",".","snRNA","snRNA","Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0030529,GO:0042254,GO:0030515,GO:0005681,GO:0031428,GO:0008380,GO:0000398","RNA binding,ribonucleoprotein complex,ribosome biogenesis,snoRNA binding,spliceosomal complex,box C/D snoRNP complex,RNA splicing,mRNA splicing, via spliceosome","GO:0003723,GO:0005730,GO:0030529,GO:0042254,GO:0005515,GO:0030515,GO:0005634,GO:0005654,GO:0005681,GO:0031428,GO:0010467,GO:0008380,GO:0000398","RNA binding,nucleolus,ribonucleoprotein complex,ribosome biogenesis,protein binding,snoRNA binding,nucleus,nucleoplasm,spliceosomal complex,box C/D snoRNP complex,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["EIF2B2","eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa [Source:HGNC Symbol;Acc:3258]","ENSG00000119718","ENSP00000266126",1,"IF-2B[1]","family-374","EIF2B2",".",".","mRNA","putative mRNA","eiF2B complex",".",".",".",".",".",".","GO:0003743,GO:0005851,GO:0006412,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 2B complex,translation,regulation of translational initiation,translational initiation","GO:0044237,GO:0005515,GO:0005524,GO:0005525,GO:0005085,GO:0003743,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0014003,GO:0010467,GO:0007417,GO:0009749,GO:0006446,GO:0001541,GO:0042552,GO:0009408,GO:0044267,GO:0043434,GO:0006413,GO:0051716","cellular metabolic process,protein binding,ATP binding,GTP binding,guanyl-nucleotide exchange factor activity,translation initiation factor activity,cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex,translation,oligodendrocyte development,gene expression,central nervous system development,response to glucose,regulation of translational initiation,ovarian follicle development,myelination,response to heat,cellular protein metabolic process,response to peptide hormone,translational initiation,cellular response to stimulus"," LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER; VWM"]
["RNF113B","ring finger protein 113B [Source:HGNC Symbol;Acc:17267]","ENSG00000139797","ENSP00000267291",2,"zf-CCCH[1],zf-C3HC4_3[1]","family-375","RNF113A,RNF113B","RNF113A","RNF113B[68,72]","snRNA","putative snRNA/mRNA","by homology",".",".",".",".",".",1,".",".","GO:0005515,GO:0008270,GO:0046872","protein binding,zinc ion binding,metal ion binding","."]
["RNF113A","ring finger protein 113A [Source:HGNC Symbol;Acc:12974]","ENSG00000125352","ENSP00000360497",2,"zf-CCCH[1],zf-C3HC4_2[1]","family-375","RNF113A,RNF113B","RNF113A","RNF113B[68,72]","snRNA","putative snRNA/mRNA","by homology, 11884590, Cwc24",".",".",".",".",".",1,".",".","GO:0005515,GO:0008270,GO:0046872","protein binding,zinc ion binding,metal ion binding","."]
["INTS10","integrator complex subunit 10 [Source:HGNC Symbol;Acc:25548] [Type: protein coding Ensembl/Havana merge]","ENSG00000104613","ENSP00000381064",".",".","family-376","INTS10",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0032039,GO:0016180,GO:0005515,GO:0005634,GO:0005737","integrator complex,snRNA processing,protein binding,nucleus,cytoplasm","."]
["LENG9","Leukocyte receptor cluster (LRC) member 9  [Source:UniProtKB/TrEMBL;Acc:B0VJZ1]","ENSG00000262887","ENSP00000458921",3,"AKAP7_NLS[1],DUF504[1],zf-CCCH[1]","family-377","LENG9",".",".","unknown","unknown","by homology",".",".",".",".",".",1,".",".","GO:0046872,GO:0003824","metal ion binding,catalytic activity","."]
["RPS29","ribosomal protein S29 [Source:HGNC Symbol;Acc:10419]","ENSG00000213741","ENSP00000245458",1,"Ribosomal_S14[1]","family-378","RPS29",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0008270,GO:0003735,GO:0005737,GO:0005829,GO:0005622,GO:0022627,GO:0005840,GO:0015935,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","zinc ion binding,structural constituent of ribosome,cytoplasm,cytosol,intracellular,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["NOP16","NOP16 nucleolar protein [Source:HGNC Symbol;Acc:26934]","ENSG00000048162","ENSP00000427489",1,"Nop16[1]","family-379","NOP16",".",".","rRNA","putative rRNA",11583614,"candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005634,GO:0043231,GO:0005730","nucleus,intracellular membrane-bounded organelle,nucleolus","."]
["U2AF1","U2 small nuclear RNA auxiliary factor 1 [Source:HGNC Symbol;Acc:12453]","ENSG00000160201","ENSP00000369629",3,"RRM_5[1],zf-CCCH[2]","family-38","U2AF1,U2AF1L4","U2AF1","U2AF1L4[43,51]","mRNA","mRNA","binds polypyrimidine tracts in introns","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005681,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124","RNA binding,spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0046872,GO:0050733,GO:0005634,GO:0005654,GO:0005681,GO:0016607,GO:0015030,GO:0071013,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","nucleotide binding,RNA binding,protein binding,nucleic acid binding,metal ion binding,RS domain binding,nucleus,nucleoplasm,spliceosomal complex,nuclear speck,Cajal body,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["U2AF1L4","U2 small nuclear RNA auxiliary factor 1-like 4 [Source:HGNC Symbol;Acc:23020]","ENSG00000161265","ENSP00000368258",3,"RRM_5[1],zf-CCCH[2]","family-38","U2AF1,U2AF1L4","U2AF1","U2AF1L4[43,51]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380","RNA binding,spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0046872,GO:0005634,GO:0005681,GO:0016607,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,metal ion binding,nucleus,spliceosomal complex,nuclear speck,mRNA processing,RNA splicing","."]
["RANBP6","RAN binding protein 6 [Source:HGNC Symbol;Acc:9851]","ENSG00000137040","ENSP00000259569",2,"HEAT_2[2]","family-380","IPO5,RANBP6","IPO5","RANBP6[78,79]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".","GO:0005515,GO:0005488,GO:0005634,GO:0005737,GO:0015031","protein binding,binding,nucleus,cytoplasm,protein transport","."]
["IPO5","importin 5 [Source:HGNC Symbol;Acc:6402]","ENSG00000065150","ENSP00000350219",3,"IBN_N[1],HEAT_2[1],HEAT[1]","family-380","IPO5,RANBP6","IPO5","RANBP6[78,79]","mRNA","putative mRBP transport","Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. [provided by RefSeq, Jul 2008]","candidate mRNA binder",".",".",1,1,".","GO:0006610","ribosomal protein import into nucleus","GO:0005488,GO:0005515,GO:0008565,GO:0005634,GO:0006607,GO:0008536,GO:0006886,GO:0005095,GO:0005737,GO:0005730,GO:0005643,GO:0006610,GO:0042307,GO:0071230,GO:0019048","binding,protein binding,protein transporter activity,nucleus,NLS-bearing protein import into nucleus,Ran GTPase binding,intracellular protein transport,GTPase inhibitor activity,cytoplasm,nucleolus,nuclear pore,ribosomal protein import into nucleus,positive regulation of protein import into nucleus,cellular response to amino acid stimulus,modulation by virus of host morphology or physiology","."]
["THOC7","THO complex 7 homolog (Drosophila) [Source:HGNC Symbol;Acc:29874]","ENSG00000163634","ENSP00000295899",1,"THOC7[1]","family-381","THOC7",".",".","mRNA","mRNA",19059247,".",".",".",".",".",".","GO:0003723,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0006406","RNA binding,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0016607,GO:0000346,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0006406,GO:0046784","RNA binding,protein binding,nucleus,cytoplasm,nuclear speck,transcription export complex,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus,viral mRNA export from host cell nucleus","."]
["DNMT3B","DNA (cytosine-5-)-methyltransferase 3 beta [Source:HGNC Symbol;Acc:2979]","ENSG00000088305","ENSP00000328547",2,"DNA_methylase[1],PWWP[1]","family-382","DNMT3A,DNMT3L,DNMT3B","DNMT3A","DNMT3L[16,38],DNMT3B[46,49]","diverse","ncRNA/DNA hybrid",20952535,".",".",".",".",".",".",".",".","GO:0003714,GO:0005515,GO:0046872,GO:0003677,GO:0008168,GO:0003886,GO:0009008,GO:0005634,GO:0043231,GO:0005720,GO:0000122,GO:0010628,GO:0006306,GO:0006346,GO:0006349,GO:0051571,GO:0051573,GO:0071230,GO:0031503,GO:0051718,GO:0045322,GO:0000792,GO:0005737,GO:0090116,GO:0042493,GO:0046499,GO:0010424,GO:0046498,GO:0045666,GO:0045892,GO:0010212","transcription corepressor activity,protein binding,metal ion binding,DNA binding,methyltransferase activity,DNA (cytosine-5-)-methyltransferase activity,DNA-methyltransferase activity,nucleus,intracellular membrane-bounded organelle,nuclear heterochromatin,negative regulation of transcription from RNA polymerase II promoter,positive regulation of gene expression,DNA methylation,methylation-dependent chromatin silencing,regulation of gene expression by genetic imprinting,positive regulation of histone H3-K4 methylation,negative regulation of histone H3-K9 methylation,cellular response to amino acid stimulus,protein complex localization,DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates,unmethylated CpG binding,heterochromatin,cytoplasm,C-5 methylation of cytosine,response to drug,S-adenosylmethioninamine metabolic process,DNA methylation on cytosine within a CG sequence,S-adenosylhomocysteine metabolic process,positive regulation of neuron differentiation,negative regulation of transcription, DNA-dependent,response to ionizing radiation"," IMMUNODEFICIENCY-CENTROMERIC INSTABILITY-FACIAL ANOMALIES SYNDROME"]
["GFM1","G elongation factor, mitochondrial 1 [Source:HGNC Symbol;Acc:13780]","ENSG00000168827","ENSP00000264263",5,"EFG_C[1],GTP_EFTU_D2[1],EFG_IV[1],EFG_II[1],GTP_EFTU[1]","family-383","GFM1",".",".","mRNA","mRNA","This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]",".","novel",".",1,".",".","GO:0003746,GO:0006414,GO:0070125","translation elongation factor activity,translational elongation,mitochondrial translational elongation","GO:0005525,GO:0003924,GO:0005739,GO:0005515,GO:0003746,GO:0005622,GO:0006414,GO:0006184,GO:0070125","GTP binding,GTPase activity,mitochondrion,protein binding,translation elongation factor activity,intracellular,translational elongation,GTP catabolic process,mitochondrial translational elongation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 1; COXPD1"]
["RNASE9","ribonuclease, RNase A family, 9 (non-active) [Source:HGNC Symbol;Acc:20673]","ENSG00000188655","ENSP00000451565",1,"RnaseA[1]","family-384","RNASE9",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016892,GO:0005576","nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region","."]
["PLRG1","pleiotropic regulator 1 [Source:HGNC Symbol;Acc:9089]","ENSG00000171566","ENSP00000424417",6,"WD40[6]","family-385","PLRG1",".",".","mRNA","mRNA/snoRNA","This gene encodes a core component of the cell division cycle 5-like (CDC5L) complex. The CDC5L complex is part of the spliceosome and is required for pre-mRNA splicing. The encoded protein plays a critical role in alternative splice site selection. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]",".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0003714,GO:0004871,GO:0005634,GO:0016607,GO:0071013,GO:0007165,GO:0000398","protein binding,transcription corepressor activity,signal transducer activity,nucleus,nuclear speck,catalytic step 2 spliceosome,signal transduction,mRNA splicing, via spliceosome","."]
["REXO1","REX1, RNA exonuclease 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24616]","ENSG00000079313","ENSP00000170168",1,"RNase_T[1]","family-386","REXO1",".",".","rRNA","putative rRNA","Rex1p",".",".",".",".",".",".","GO:0004527","exonuclease activity","GO:0003676,GO:0004527,GO:0005634","nucleic acid binding,exonuclease activity,nucleus","."]
["ZC3HAV1L","zinc finger CCCH-type, antiviral 1-like [Source:HGNC Symbol;Acc:22423] [Type: protein coding Ensembl/Havana merge]","ENSG00000146858","ENSP00000275766",".",".","family-387","ZC3HAV1L",".",".","unknown","unknown","established RBP ",".",".",".",".",".",1,".",".",".",".","."]
["LSM14A","LSM14A, SCD6 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:24489]","ENSG00000262860","ENSP00000460896",2,"LSM14[1],FDF[1]","family-388","LSM14A,LSM14B","LSM14A","LSM14B[46,56]","mRNA","mRNA /viral RNA",16484376,"RNAbinding","RNArelated",1,1,1,".","GO:0003725,GO:0003727,GO:0000932,GO:0010494,GO:0006417,GO:0033962,GO:0039529","double-stranded RNA binding,single-stranded RNA binding,cytoplasmic mRNA processing body,cytoplasmic stress granule,regulation of translation,cytoplasmic mRNA processing body assembly,RIG-I signaling pathway","GO:0003690,GO:0003725,GO:0003727,GO:0005737,GO:0000932,GO:0043231,GO:0010494,GO:0007275,GO:0006417,GO:0060340,GO:0033962,GO:0039529,GO:0051607","double-stranded DNA binding,double-stranded RNA binding,single-stranded RNA binding,cytoplasm,cytoplasmic mRNA processing body,intracellular membrane-bounded organelle,cytoplasmic stress granule,multicellular organismal development,regulation of translation,positive regulation of type I interferon-mediated signaling pathway,cytoplasmic mRNA processing body assembly,RIG-I signaling pathway,defense response to virus","."]
["LSM14B","LSM14B, SCD6 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:15887]","ENSG00000149657","ENSP00000383172",2,"LSM14[1],FDF[1]","family-388","LSM14A,LSM14B","LSM14A","LSM14B[46,56]","mRNA","mRNA /viral RNA","established RBP ","RNAbinding",".",".",1,1,".","GO:0030529,GO:0006417","ribonucleoprotein complex,regulation of translation","GO:0030529,GO:0007275,GO:0006417","ribonucleoprotein complex,multicellular organismal development,regulation of translation","."]
["LUZP4","leucine zipper protein 4 [Source:HGNC Symbol;Acc:24971]","ENSG00000267900","ENSP00000472441",1,"FYTT[1]","family-389","LUZP4",".",".","mRNA","putative mRNA","This gene encodes a protein which contains two sets of heptad repeats in the N-terminus; the C-terminal most repeats form a leucine zipper domain. The presence of a leucine zipper domain suggests the protein may have DNA-binding activity and the protein has been shown to localize with a spliceosome protein (PMID: 12032826). [provided by RefSeq, Aug 2011]",".",".",".",".",".",".",".",".","GO:0005634","nucleus","."]
["TDRD6","tudor domain containing 6 [Source:HGNC Symbol;Acc:21339]","ENSG00000180113","ENSP00000443299",7,"TUDOR[7]","family-39","TDRD15,TDRD6","TDRD15","TDRD6[24,22]","ncRNA","piRNA related",19345099,".",".",".",".",".",".","GO:0043186,GO:0030529","P granule,ribonucleoprotein complex","GO:0005737,GO:0005783,GO:0033391,GO:0043186,GO:0007275,GO:0007283,GO:0007281,GO:0030529","cytoplasm,endoplasmic reticulum,chromatoid body,P granule,multicellular organismal development,spermatogenesis,germ cell development,ribonucleoprotein complex","."]
["TDRD15","tudor domain containing 15 [Source:HGNC Symbol;Acc:45037]","ENSG00000218819","ENSP00000384376",8,"TUDOR[8]","family-39","TDRD15,TDRD6","TDRD15","TDRD6[24,22]","unknown","RNA related","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016788","nucleic acid binding,hydrolase activity, acting on ester bonds","."]
["MRPS22","mitochondrial ribosomal protein S22 [Source:HGNC Symbol;Acc:14508]","ENSG00000175110","ENSP00000420229",1,"MRP-S22[1]","family-390","MRPS22",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005761,GO:0005763,GO:0005840","structural constituent of ribosome,mitochondrial ribosome,mitochondrial small ribosomal subunit,ribosome","GO:0003735,GO:0005739,GO:0005761,GO:0005763,GO:0005840","structural constituent of ribosome,mitochondrion,mitochondrial ribosome,mitochondrial small ribosomal subunit,ribosome"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 5; COXPD5"]
["EEF1B2","eukaryotic translation elongation factor 1 beta 2 [Source:HGNC Symbol;Acc:3208]","ENSG00000114942","ENSP00000376056",2,"EF1_GNE[1],EF-1_beta_acid[1]","family-391","EEF1B2,EEF1D","EEF1B2","EEF1D[57,20]","tRNA","tRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0003746,GO:0005853,GO:0006412,GO:0006414","translation elongation factor activity,eukaryotic translation elongation factor 1 complex,translation,translational elongation","GO:0005515,GO:0003746,GO:0005829,GO:0005853,GO:0006412,GO:0010467,GO:0044267,GO:0006414","protein binding,translation elongation factor activity,cytosol,eukaryotic translation elongation factor 1 complex,translation,gene expression,cellular protein metabolic process,translational elongation","."]
["EEF1D","eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) [Source:HGNC Symbol;Acc:3211]","ENSG00000104529","ENSP00000433611",2,"EF1_GNE[1],EF-1_beta_acid[1]","family-391","EEF1B2,EEF1D","EEF1B2","EEF1D[57,20]","tRNA","tRNA/mRNA","This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]",".",".",".",".",".",".","GO:0003746,GO:0008135,GO:0005853,GO:0006412,GO:0006414","translation elongation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation elongation factor 1 complex,translation,translational elongation","GO:0005515,GO:0003677,GO:0004871,GO:0003746,GO:0008135,GO:0005634,GO:0005829,GO:0005853,GO:0006351,GO:0043123,GO:0006412,GO:0006355,GO:0007165,GO:0010467,GO:0044267,GO:0006414","protein binding,DNA binding,signal transducer activity,translation elongation factor activity,translation factor activity, nucleic acid binding,nucleus,cytosol,eukaryotic translation elongation factor 1 complex,transcription, DNA-templated,positive regulation of I-kappaB kinase/NF-kappaB signaling,translation,regulation of transcription, DNA-dependent,signal transduction,gene expression,cellular protein metabolic process,translational elongation","."]
["SIDT1","SID1 transmembrane family, member 1 [Source:HGNC Symbol;Acc:25967]","ENSG00000072858","ENSP00000264852",1,"SID-1_RNA_chan[1]","family-392","SIDT1,SIDT2","SIDT1","SIDT2[58,57]","ncRNA","miRNA/siRNA",15850781,".",".",".",".",".",".","GO:0051033,GO:0033227","RNA transmembrane transporter activity,dsRNA transport","GO:0051033,GO:0016021,GO:0033227","RNA transmembrane transporter activity,integral to membrane,dsRNA transport","."]
["SIDT2","SID1 transmembrane family, member 2 [Source:HGNC Symbol;Acc:24272]","ENSG00000149577","ENSP00000314023",1,"SID-1_RNA_chan[1]","family-392","SIDT1,SIDT2","SIDT1","SIDT2[58,57]","ncRNA","putative miRNA/siRNA","by homology",".",".",".",".",".",".","GO:0051033,GO:0033227","RNA transmembrane transporter activity,dsRNA transport","GO:0051033,GO:0016021,GO:0005765,GO:0033227","RNA transmembrane transporter activity,integral to membrane,lysosomal membrane,dsRNA transport","."]
["TRMT44","tRNA methyltransferase 44 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26653]","ENSG00000155275","ENSP00000374387",1,"AdoMet_MTase[1]","family-393","TRMT44",".",".","tRNA","putative tRNA","The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively. [provided by RefSeq, May 2012]",".",".",".",".",".",1,"GO:0008033","tRNA processing","GO:0046872,GO:0008168,GO:0005737,GO:0008033","metal ion binding,methyltransferase activity,cytoplasm,tRNA processing","."]
["GPATCH8","G patch domain containing 8 [Source:HGNC Symbol;Acc:29066]","ENSG00000186566","ENSP00000467556",2,"G-patch[1],zf-C2H2_jaz[1]","family-394","GPATCH8,ZNF804B,ZNF804A","GPATCH8","ZNF804B[20,22],ZNF804A[21,26]","unknown","unknown","established RBP ","candidate mRNA binder",".",".",1,".",".",".",".","GO:0005515,GO:0003676,GO:0046872","protein binding,nucleic acid binding,metal ion binding","."]
["WDR4","WD repeat domain 4 [Source:HGNC Symbol;Acc:12756]","ENSG00000160193","ENSP00000381266",1,"WD40[1]","family-395","WDR4",".",".","tRNA","tRNA",12403464,".",".",".",".",".",".","GO:0008176,GO:0006400,GO:0036265","tRNA (guanine-N7-)-methyltransferase activity,tRNA modification,RNA (guanine-N7)-methylation","GO:0005515,GO:0008176,GO:0005634,GO:0005737,GO:0005654,GO:0006400,GO:0036265","protein binding,tRNA (guanine-N7-)-methyltransferase activity,nucleus,cytoplasm,nucleoplasm,tRNA modification,RNA (guanine-N7)-methylation","."]
["SLIRP","SRA stem-loop interacting RNA binding protein [Source:HGNC Symbol;Acc:20495]","ENSG00000119705","ENSP00000450909",1,"RRM_1[1]","family-396","SLIRP",".",".","ncRNA","miRNA/ncRNA/mRNA","Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0000961","RNA binding,ribonucleoprotein complex,negative regulation of mitochondrial RNA catabolic process","GO:0000166,GO:0003676,GO:0005739,GO:0003723,GO:0005634,GO:0030529,GO:0006351,GO:0006355,GO:0000961","nucleotide binding,nucleic acid binding,mitochondrion,RNA binding,nucleus,ribonucleoprotein complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,negative regulation of mitochondrial RNA catabolic process","."]
["ATXN1","ataxin 1 [Source:HGNC Symbol;Acc:10548]","ENSG00000124788","ENSP00000416360",2,"ATXN-1_C[1],AXH[1]","family-397","ATXN1,ATXN1L","ATXN1","ATXN1L[28,33]","mRNA","mRNA","15615787, 11136710",".",".",".",".",".",".","GO:0003723,GO:0034046,GO:0008266,GO:0042272,GO:0006396","RNA binding,poly(G) RNA binding,poly(U) RNA binding,nuclear RNA export factor complex,RNA processing","GO:0003723,GO:0005515,GO:0003677,GO:0043621,GO:0042802,GO:0008022,GO:0034046,GO:0008266,GO:0005634,GO:0005737,GO:0043231,GO:0005654,GO:0016363,GO:0042405,GO:0042272,GO:0006351,GO:0045944,GO:0045892,GO:0006396,GO:0060079,GO:0008344,GO:0008542,GO:0008219,GO:0042326,GO:0043569,GO:0051168","RNA binding,protein binding,DNA binding,protein self-association,identical protein binding,protein C-terminus binding,poly(G) RNA binding,poly(U) RNA binding,nucleus,cytoplasm,intracellular membrane-bounded organelle,nucleoplasm,nuclear matrix,nuclear inclusion body,nuclear RNA export factor complex,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,negative regulation of transcription, DNA-dependent,RNA processing,regulation of excitatory postsynaptic membrane potential,adult locomotory behavior,visual learning,cell death,negative regulation of phosphorylation,negative regulation of insulin-like growth factor receptor signaling pathway,nuclear export"," SPINOCEREBELLAR ATAXIA 1; SCA1"]
["ATXN1L","ataxin 1-like [Source:HGNC Symbol;Acc:33279]","ENSG00000224470","ENSP00000415822",1,"AXH[1]","family-397","ATXN1,ATXN1L","ATXN1","ATXN1L[28,33]","mRNA","putative mRNA","established RBP ",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0003677,GO:0005634,GO:0030425,GO:0006351,GO:0006355","RNA binding,protein binding,DNA binding,nucleus,dendrite,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["YTHDF1","YTH domain family, member 1 [Source:HGNC Symbol;Acc:15867]","ENSG00000149658","ENSP00000359358",1,"YTH[1]","family-398","YTHDF1,YTHDF3,YTHDF2","YTHDF1","YTHDF3[69,66],YTHDF2[66,64]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,".",1,".",".",".",".","."]
["YTHDF2","YTH domain family, member 2 [Source:HGNC Symbol;Acc:31675]","ENSG00000198492","ENSP00000444660",1,"YTH[1]","family-398","YTHDF1,YTHDF3,YTHDF2","YTHDF1","YTHDF3[69,66],YTHDF2[66,64]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,1,1,".",".","GO:0006959","humoral immune response","."]
["YTHDF3","YTH domain family, member 3 [Source:HGNC Symbol;Acc:26465]","ENSG00000185728","ENSP00000473387",1,"YTH[1]","family-398","YTHDF1,YTHDF3,YTHDF2","YTHDF1","YTHDF3[69,66],YTHDF2[66,64]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,1,1,".",".",".",".","."]
["LRPPRC","leucine-rich pentatricopeptide repeat containing [Source:HGNC Symbol;Acc:15714]","ENSG00000138095","ENSP00000260665",3,"PPR_2[2],PPR[1]","family-399","LRPPRC",".",".","mRNA","mRNA",22045337,"RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0030529,GO:0051028,GO:0000961","RNA binding,ribonucleoprotein complex,mRNA transport,negative regulation of mitochondrial RNA catabolic process","GO:0005739,GO:0003723,GO:0005515,GO:0003697,GO:0008017,GO:0048487,GO:0005634,GO:0048471,GO:0005856,GO:0005874,GO:0005654,GO:0030529,GO:0000794,GO:0005637,GO:0042645,GO:0005640,GO:0006351,GO:0006355,GO:0051028,GO:0047497,GO:0000961,GO:0070129,GO:0005737","mitochondrion,RNA binding,protein binding,single-stranded DNA binding,microtubule binding,beta-tubulin binding,nucleus,perinuclear region of cytoplasm,cytoskeleton,microtubule,nucleoplasm,ribonucleoprotein complex,condensed nuclear chromosome,nuclear inner membrane,mitochondrial nucleoid,nuclear outer membrane,transcription, DNA-templated,regulation of transcription, DNA-dependent,mRNA transport,mitochondrion transport along microtubule,negative regulation of mitochondrial RNA catabolic process,regulation of mitochondrial translation,cytoplasm"," LEIGH SYNDROME, FRENCH CANADIAN TYPE; LSFC"]
["TFIP11","tuftelin interacting protein 11 [Source:HGNC Symbol;Acc:17165]","ENSG00000100109","ENSP00000384297",3,"G-patch[1],TIP_N[1],GCFC[1]","family-4","TFIP11",".",".","mRNA","mRNA","TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008 [PubMed 18367544]).[supplied by OMIM, Apr 2009]",".",".",".",".",".",".","GO:0005681,GO:0071013,GO:0000398,GO:0006396","spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,RNA processing","GO:0005578,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0071013,GO:0031214,GO:0006355,GO:0000398,GO:0006396,GO:0005515","proteinaceous extracellular matrix,nucleic acid binding,DNA binding,nucleus,cytoplasm,spliceosomal complex,nuclear speck,catalytic step 2 spliceosome,biomineral tissue development,regulation of transcription, DNA-dependent,mRNA splicing, via spliceosome,RNA processing,protein binding","."]
["ILF2","interleukin enhancer binding factor 2 [Source:HGNC Symbol;Acc:6037]","ENSG00000143621","ENSP00000355011",1,"DZF[1]","family-40","ILF2,STRBP,ILF3","ILF2","STRBP[20,12],ILF3[22,9]","mRNA","mRNA",23129811,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0003725,GO:0030529","RNA binding,double-stranded RNA binding,ribonucleoprotein complex","GO:0003723,GO:0005524,GO:0016740,GO:0006955,GO:0005515,GO:0003677,GO:0003725,GO:0005634,GO:0005737,GO:0005730,GO:0030529,GO:0006351,GO:0045893","RNA binding,ATP binding,transferase activity,immune response,protein binding,DNA binding,double-stranded RNA binding,nucleus,cytoplasm,nucleolus,ribonucleoprotein complex,transcription, DNA-templated,positive regulation of transcription, DNA-dependent","."]
["STRBP","spermatid perinuclear RNA binding protein [Source:HGNC Symbol;Acc:16462]","ENSG00000165209","ENSP00000321347",3,"dsrm[2],DZF[1]","family-40","ILF2,STRBP,ILF3","ILF2","STRBP[20,12],ILF3[22,9]","mRNA","putative mRNA","by homology","RNAbinding","experimentally validated",1,1,".",".","GO:0003725,GO:0003727","double-stranded RNA binding,single-stranded RNA binding","GO:0003677,GO:0003725,GO:0003727,GO:0005634,GO:0005737,GO:0015630,GO:0007275,GO:0007286,GO:0006928,GO:0007638","DNA binding,double-stranded RNA binding,single-stranded RNA binding,nucleus,cytoplasm,microtubule cytoskeleton,multicellular organismal development,spermatid development,cellular component movement,mechanosensory behavior","."]
["ILF3","interleukin enhancer binding factor 3, 90kDa [Source:HGNC Symbol;Acc:6038]","ENSG00000129351","ENSP00000384660",3,"dsrm[2],DZF[1]","family-40","ILF2,STRBP,ILF3","ILF2","STRBP[20,12],ILF3[22,9]","mRNA","mRNA","This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein was first discovered to be a subunit of the nuclear factor of activated T-cells (NFAT); a transcription factor required for T-cell expression of interleukin 2. NFAT is a heterodimer of 45 kDa and 90 kDa proteins, the larger of which is the product of this gene. These proteins have been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth; possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2008]","translationfactor","RNAbinding",1,1,1,".","GO:0003723,GO:0003725,GO:0030529","RNA binding,double-stranded RNA binding,ribonucleoprotein complex","GO:0003723,GO:0005515,GO:0003677,GO:0003725,GO:0005634,GO:0005737,GO:0005739,GO:0005730,GO:0030529,GO:0006351,GO:0045893,GO:0045892,GO:0045071,GO:0006468,GO:0051607,GO:0017148,GO:0000279","RNA binding,protein binding,DNA binding,double-stranded RNA binding,nucleus,cytoplasm,mitochondrion,nucleolus,ribonucleoprotein complex,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,negative regulation of transcription, DNA-dependent,negative regulation of viral genome replication,protein phosphorylation,defense response to virus,negative regulation of translation,M phase","."]
["TCERG1","transcription elongation regulator 1 [Source:HGNC Symbol;Acc:15630]","ENSG00000113649","ENSP00000296702",9,"FF[6],WW[3]","family-400","TCERG1,TCERG1L","TCERG1","TCERG1L[18,34]","mRNA","mRNA","18187414, 23436654","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0005515,GO:0003713,GO:0001106,GO:0070064,GO:0001103,GO:0005634,GO:0000122,GO:0006366","protein binding,transcription coactivator activity,RNA polymerase II transcription corepressor activity,proline-rich region binding,RNA polymerase II repressing transcription factor binding,nucleus,negative regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter","."]
["NXF5","nuclear RNA export factor 5 [Source:HGNC Symbol;Acc:8075]","ENSG00000126952","ENSP00000442401",2,"LRR_4[1],Tap-RNA_bind[1]","family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","NXF1","NXF3[44,51],NXF2B[58,58],NXF5[35,59],NXF2[58,58]","mRNA","mRNA",11566096,".",".",".",".",".",".","GO:0003723,GO:0006406,GO:0050658","RNA binding,mRNA export from nucleus,RNA transport","GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0015629,GO:0007275,GO:0006406,GO:0050658","nucleotide binding,RNA binding,protein binding,nucleus,cytoplasm,actin cytoskeleton,multicellular organismal development,mRNA export from nucleus,RNA transport","."]
["NXF2B","nuclear RNA export factor 2B [Source:HGNC Symbol;Acc:23984]","ENSG00000185945","ENSP00000361836",4,"LRR_4[1],Tap-RNA_bind[1],NTF2[1],TAP_C[1]","family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","NXF1","NXF3[44,51],NXF2B[58,58],NXF5[35,59],NXF2[58,58]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0042272,GO:0051028,GO:0006406,GO:0050658","RNA binding,nuclear RNA export factor complex,mRNA transport,mRNA export from nucleus,RNA transport","GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005622,GO:0015629,GO:0042272,GO:0007275,GO:0006810,GO:0051028,GO:0006406,GO:0050658","nucleotide binding,RNA binding,protein binding,nucleus,cytoplasm,intracellular,actin cytoskeleton,nuclear RNA export factor complex,multicellular organismal development,transport,mRNA transport,mRNA export from nucleus,RNA transport","."]
["NXF2","HCG2045905, isoform CRA_a  [Source:UniProtKB/TrEMBL;Acc:D3DX98]","ENSG00000269437","ENSP00000472530",4,"LRR_4[1],Tap-RNA_bind[1],NTF2[1],TAP_C[1]","family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","NXF1","NXF3[44,51],NXF2B[58,58],NXF5[35,59],NXF2[58,58]","mRNA","mRNA","This gene encodes a member of a family of nuclear RNA export proteins. The encoded protein is associated with the nuclear envelope and aids in the export of mRNAs. There is a closely related paralog of this gene located adjacent on chromosome X and on the opposite strand. [provided by RefSeq, Aug 2013]",".",".",".",".",".",".","GO:0003723,GO:0042272,GO:0051028,GO:0006406,GO:0050658","RNA binding,nuclear RNA export factor complex,mRNA transport,mRNA export from nucleus,RNA transport","GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005622,GO:0015629,GO:0042272,GO:0007275,GO:0006810,GO:0051028,GO:0006406,GO:0050658","nucleotide binding,RNA binding,protein binding,nucleus,cytoplasm,intracellular,actin cytoskeleton,nuclear RNA export factor complex,multicellular organismal development,transport,mRNA transport,mRNA export from nucleus,RNA transport","."]
["NXF1","nuclear RNA export factor 1 [Source:HGNC Symbol;Acc:8071]","ENSG00000162231","ENSP00000294172",4,"LRR_4[1],Tap-RNA_bind[1],NTF2[1],TAP_C[1]","family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","NXF1","NXF3[44,51],NXF2B[58,58],NXF5[35,59],NXF2[58,58]","mRNA","mRNA","This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]","RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0003729,GO:0016973,GO:0006406,GO:0051028,GO:0006405","RNA binding,mRNA binding,poly(A)+ mRNA export from nucleus,mRNA export from nucleus,mRNA transport,RNA export from nucleus","GO:0000166,GO:0003723,GO:0005515,GO:0003729,GO:0005487,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005643,GO:0016607,GO:0042405,GO:0000346,GO:0010467,GO:0016973,GO:0006406,GO:0019048,GO:0005622,GO:0006810,GO:0051028,GO:0006405","nucleotide binding,RNA binding,protein binding,mRNA binding,nucleocytoplasmic transporter activity,nucleus,cytoplasm,cytosol,nucleoplasm,nuclear pore,nuclear speck,nuclear inclusion body,transcription export complex,gene expression,poly(A)+ mRNA export from nucleus,mRNA export from nucleus,modulation by virus of host morphology or physiology,intracellular,transport,mRNA transport,RNA export from nucleus","."]
["NXF3","nuclear RNA export factor 3 [Source:HGNC Symbol;Acc:8073]","ENSG00000147206","ENSP00000404017",2,"Tap-RNA_bind[1],NTF2[1]","family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","NXF1","NXF3[44,51],NXF2B[58,58],NXF5[35,59],NXF2[58,58]","mRNA","putative mRNA","This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0006406,GO:0003729,GO:0042272,GO:0016973","RNA binding,mRNA export from nucleus,mRNA binding,nuclear RNA export factor complex,poly(A)+ mRNA export from nucleus","GO:0000166,GO:0003723,GO:0005634,GO:0005737,GO:0006406,GO:0005622,GO:0006810,GO:0005515,GO:0003729,GO:0042272,GO:0016973","nucleotide binding,RNA binding,nucleus,cytoplasm,mRNA export from nucleus,intracellular,transport,protein binding,mRNA binding,nuclear RNA export factor complex,poly(A)+ mRNA export from nucleus","."]
["ZRSR1","zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1 [Source:HGNC Symbol;Acc:12456]","ENSG00000212643","ENSP00000375133",3,"RRM_5[1],zf-CCCH[2]","family-402","ZRSR1,ZRSR2","ZRSR1","ZRSR2[92,92]","mRNA","putative mRNA","by homology, 12558503",".",".",".",".",".",1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0003676,GO:0046872,GO:0005634,GO:0030529","nucleotide binding,RNA binding,nucleic acid binding,metal ion binding,nucleus,ribonucleoprotein complex","."]
["ZRSR2","zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 [Source:HGNC Symbol;Acc:23019]","ENSG00000169249","ENSP00000303015",3,"RRM_5[1],zf-CCCH[2]","family-402","ZRSR1,ZRSR2","ZRSR1","ZRSR2[92,92]","mRNA","mRNA","This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008",".",".",".",".",".",1,"GO:0030628,GO:0005689,GO:0008380,GO:0000398,GO:0000245","pre-mRNA 3'-splice site binding,U12-type spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly","GO:0000166,GO:0005515,GO:0003676,GO:0046872,GO:0030628,GO:0005689,GO:0008380,GO:0000398,GO:0000245","nucleotide binding,protein binding,nucleic acid binding,metal ion binding,pre-mRNA 3'-splice site binding,U12-type spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly","."]
["MRPL35","mitochondrial ribosomal protein L35 [Source:HGNC Symbol;Acc:14489]","ENSG00000132313","ENSP00000338389",1,"Ribosomal_L35p[1]","family-403","MRPL35",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,ribosome,translation,mitochondrial ribosome","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005739,GO:0005761","structural constituent of ribosome,intracellular,ribosome,translation,mitochondrion,mitochondrial ribosome","."]
["RRS1","RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17083]","ENSG00000179041","ENSP00000322396",1,"RRS1[1]","family-404","RRS1",".",".","rRNA","rRNA","RRS1 yeast homolog 17938242","candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005515,GO:0005730,GO:0005634,GO:0005783,GO:0000794,GO:0042254,GO:0007080","protein binding,nucleolus,nucleus,endoplasmic reticulum,condensed nuclear chromosome,ribosome biogenesis,mitotic metaphase plate congression","."]
["PRKDC","protein kinase, DNA-activated, catalytic polypeptide [Source:HGNC Symbol;Acc:9413]","ENSG00000253729","ENSP00000442177",1,"PI3_PI4_kinase[1]","family-405","PRKDC",".",".","mRNA","putative mRNA",14704337,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005488,GO:0005515,GO:0005524,GO:0003677,GO:0019899,GO:0016773,GO:0016772,GO:0004677,GO:0005634,GO:0006915,GO:0007507,GO:0007420,GO:0001756,GO:0043065,GO:0000723,GO:0006303,GO:0006302,GO:0010332,GO:0033077,GO:0033152,GO:0033153,GO:0002326,GO:0002360,GO:0031648,GO:0002328,GO:0035234,GO:0004674,GO:0004672,GO:0008134,GO:0005667,GO:0005829,GO:0005730,GO:0005654,GO:0070419,GO:0005958,GO:0008630,GO:0030098,GO:0045944,GO:0045087,GO:0006464,GO:0006281,GO:0032869,GO:0018105,GO:0032481","binding,protein binding,ATP binding,DNA binding,enzyme binding,phosphotransferase activity, alcohol group as acceptor,transferase activity, transferring phosphorus-containing groups,DNA-dependent protein kinase activity,nucleus,apoptotic process,heart development,brain development,somitogenesis,positive regulation of apoptotic process,telomere maintenance,double-strand break repair via nonhomologous end joining,double-strand break repair,response to gamma radiation,T cell differentiation in thymus,immunoglobulin V(D)J recombination,T cell receptor V(D)J recombination,B cell lineage commitment,T cell lineage commitment,protein destabilization,pro-B cell differentiation,germ cell programmed cell death,protein serine/threonine kinase activity,protein kinase activity,transcription factor binding,transcription factor complex,cytosol,nucleolus,nucleoplasm,nonhomologous end joining complex,DNA-dependent protein kinase-DNA ligase 4 complex,intrinsic apoptotic signaling pathway in response to DNA damage,lymphocyte differentiation,positive regulation of transcription from RNA polymerase II promoter,innate immune response,cellular protein modification process,DNA repair,cellular response to insulin stimulus,peptidyl-serine phosphorylation,positive regulation of type I interferon production","."]
["NOC2L","nucleolar complex associated 2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24517]","ENSG00000188976","ENSP00000317992",1,"Noc2[1]","family-406","NOC2L",".",".","rRNA","putative rRNA","NOC 2 homolog yeast, 22658674, 22681889","candidate mRNA binder","novel",1,1,".",".",".",".","GO:0003714,GO:0005515,GO:0003682,GO:0070491,GO:0042393,GO:0031491,GO:0005488,GO:0005634,GO:0005730,GO:0005654,GO:0000122,GO:0006351,GO:0006915,GO:2001243,GO:0034644,GO:0035067,GO:0031497,GO:0002903,GO:0032066","transcription corepressor activity,protein binding,chromatin binding,repressing transcription factor binding,histone binding,nucleosome binding,binding,nucleus,nucleolus,nucleoplasm,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,apoptotic process,negative regulation of intrinsic apoptotic signaling pathway,cellular response to UV,negative regulation of histone acetylation,chromatin assembly,negative regulation of B cell apoptotic process,nucleolus to nucleoplasm transport","."]
["MTIF3","mitochondrial translational initiation factor 3 [Source:HGNC Symbol;Acc:29788] ","ENSG00000122033","ENSP00000370508",2,"IF3_C[1],IF3_N[1]","family-407","MTIF3",".",".","mRNA","putative mRNA",12095986,".",".",".",".",".",".","GO:0003743,GO:0008135,GO:0043024,GO:0006446,GO:0001732,GO:0006413,GO:0032790","translation initiation factor activity,translation factor activity, nucleic acid binding,ribosomal small subunit binding,regulation of translational initiation,formation of translation initiation complex,translational initiation,ribosome disassembly","GO:0003743,GO:0008135,GO:0043024,GO:0005739,GO:0006446,GO:0001732,GO:0006413,GO:0032790","translation initiation factor activity,translation factor activity, nucleic acid binding,ribosomal small subunit binding,mitochondrion,regulation of translational initiation,formation of translation initiation complex,translational initiation,ribosome disassembly","."]
["NOL11","nucleolar protein 11 [Source:HGNC Symbol;Acc:24557]","ENSG00000130935","ENSP00000464015",1,"NUC205[1]","family-408","NOL11",".",".","rRNA","rRNA",22916032,"candidate mRNA binder","novel",1,1,1,".","GO:0030490","maturation of SSU-rRNA","GO:0005515,GO:0005634,GO:0005730,GO:0034455,GO:0006351,GO:0030490,GO:1901838","protein binding,nucleus,nucleolus,t-UTP complex,transcription, DNA-templated,maturation of SSU-rRNA,positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter","."]
["EXOSC3","exosome component 3 [Source:HGNC Symbol;Acc:17944]","ENSG00000107371","ENSP00000323046",".",".","family-409","EXOSC3",".",".","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000175,GO:0000178,GO:0000176,GO:0000177,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928,GO:0071034","RNA binding,3'-5'-exoribonuclease activity,exosome (RNase complex),nuclear exosome (RNase complex),cytoplasmic exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,CUT catabolic process","GO:0003723,GO:0005515,GO:0000175,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0000178,GO:0000176,GO:0000177,GO:0035327,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0045190,GO:0043928,GO:0071034,GO:0045006,GO:0045830","RNA binding,protein binding,3'-5'-exoribonuclease activity,nucleus,cytoplasm,cytosol,nucleolus,exosome (RNase complex),nuclear exosome (RNase complex),cytoplasmic exosome (RNase complex),transcriptionally active chromatin,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,isotype switching,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,CUT catabolic process,DNA deamination,positive regulation of isotype switching"," PONTOCEREBELLAR HYPOPLASIA, TYPE 1B; PCH1B"]
["PNPT1","polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:23166]","ENSG00000138035","ENSP00000400646",7,"S1[1],PNPase[1],RNase_PH[2],RNase_PH_C[2],KH_1[1]","family-41","PNPT1",".",".","diverse","diverse","established RBP ","nuclease",".",".",1,".",1,"GO:0003723,GO:0000175,GO:0006396,GO:0004654,GO:0006402,GO:0034046,GO:0008266,GO:0035198,GO:0061014,GO:0043631,GO:0006401,GO:0035928,GO:0000964,GO:0000958,GO:0000962,GO:0000965,GO:0000957,GO:0035927,GO:0071042,GO:0097222,GO:2000627","RNA binding,3'-5'-exoribonuclease activity,RNA processing,polyribonucleotide nucleotidyltransferase activity,mRNA catabolic process,poly(G) RNA binding,poly(U) RNA binding,miRNA binding,positive regulation of mRNA catabolic process,RNA polyadenylation,RNA catabolic process,rRNA import into mitochondrion,mitochondrial RNA 5'-end processing,mitochondrial mRNA catabolic process,positive regulation of mitochondrial RNA catabolic process,mitochondrial RNA 3'-end processing,mitochondrial RNA catabolic process,RNA import into mitochondrion,nuclear polyadenylation-dependent mRNA catabolic process,mitochondrial mRNA polyadenylation,positive regulation of miRNA catabolic process","GO:0003723,GO:0000175,GO:0006396,GO:0004654,GO:0006402,GO:0005515,GO:0034046,GO:0008266,GO:0035198,GO:0005886,GO:0005737,GO:0005739,GO:0005758,GO:0045025,GO:0051260,GO:0035458,GO:0071850,GO:0070584,GO:0034599,GO:0070207,GO:0061014,GO:0045926,GO:0043631,GO:0006401,GO:2000772,GO:0043457,GO:0035928,GO:0000964,GO:0000958,GO:0000962,GO:0000965,GO:0000957,GO:0035927,GO:0071042,GO:0097222,GO:2000627","RNA binding,3'-5'-exoribonuclease activity,RNA processing,polyribonucleotide nucleotidyltransferase activity,mRNA catabolic process,protein binding,poly(G) RNA binding,poly(U) RNA binding,miRNA binding,plasma membrane,cytoplasm,mitochondrion,mitochondrial intermembrane space,mitochondrial degradosome,protein homooligomerization,cellular response to interferon-beta,mitotic cell cycle arrest,mitochondrion morphogenesis,cellular response to oxidative stress,protein homotrimerization,positive regulation of mRNA catabolic process,negative regulation of growth,RNA polyadenylation,RNA catabolic process,regulation of cellular senescence,regulation of cellular respiration,rRNA import into mitochondrion,mitochondrial RNA 5'-end processing,mitochondrial mRNA catabolic process,positive regulation of mitochondrial RNA catabolic process,mitochondrial RNA 3'-end processing,mitochondrial RNA catabolic process,RNA import into mitochondrion,nuclear polyadenylation-dependent mRNA catabolic process,mitochondrial mRNA polyadenylation,positive regulation of miRNA catabolic process"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 13; COXPD13"]
["TSNAX","translin-associated factor X [Source:HGNC Symbol;Acc:12380]","ENSG00000116918","ENSP00000397537",1,"Translin[1]","family-410","TSNAX",".",".","tRNA","tRNA",22773104,"RNAbinding",".",".",1,".",".",".",".","GO:0043565,GO:0032403,GO:0031687,GO:0005737,GO:0005515,GO:0046872,GO:0003677,GO:0008565,GO:0005634,GO:0048471,GO:0005794,GO:0030154,GO:0007275,GO:0007283,GO:0015031","sequence-specific DNA binding,protein complex binding,A2A adenosine receptor binding,cytoplasm,protein binding,metal ion binding,DNA binding,protein transporter activity,nucleus,perinuclear region of cytoplasm,Golgi apparatus,cell differentiation,multicellular organismal development,spermatogenesis,protein transport","."]
["RIOK1","RIO kinase 1 [Source:HGNC Symbol;Acc:18656]","ENSG00000124784","ENSP00000369162",1,"RIO1[1]","family-411","RIOK1,RIOK3","RIOK1","RIOK3[28,31]","rRNA","rRNA",22072790,".",".",".",".",".",".",".",".","GO:0005524,GO:0004674,GO:0003824,GO:0004672,GO:0016772,GO:0006468","ATP binding,protein serine/threonine kinase activity,catalytic activity,protein kinase activity,transferase activity, transferring phosphorus-containing groups,protein phosphorylation","."]
["RIOK3","RIO kinase 3 [Source:HGNC Symbol;Acc:11451]","ENSG00000101782","ENSP00000462548",1,"RIO1[1]","family-411","RIOK1,RIOK3","RIOK1","RIOK3[28,31]","rRNA","rRNA",22418843,".",".",".",".",".",".",".",".","GO:0005524,GO:0003824,GO:0005515,GO:0004674,GO:0016773,GO:0016772,GO:0016020,GO:0006468,GO:0007059,GO:0009103","ATP binding,catalytic activity,protein binding,protein serine/threonine kinase activity,phosphotransferase activity, alcohol group as acceptor,transferase activity, transferring phosphorus-containing groups,membrane,protein phosphorylation,chromosome segregation,lipopolysaccharide biosynthetic process","."]
["PIWIL1","piwi-like 1 (Drosophila) [Source:HGNC Symbol;Acc:9007]","ENSG00000125207","ENSP00000245255",3,"GAGE[1],PAZ[1],Piwi[1]","family-412","PIWIL1,PIWIL2,PIWIL3,PIWIL4","PIWIL1","PIWIL2[39,35],PIWIL3[51,49],PIWIL4[49,50]","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0003727,GO:0003729,GO:0034584,GO:0005845,GO:0034587,GO:0043186,GO:0006417,GO:0031047","single-stranded RNA binding,mRNA binding,piRNA binding,mRNA cap binding complex,piRNA metabolic process,P granule,regulation of translation,gene silencing by RNA","GO:0005515,GO:0003727,GO:0003729,GO:0034584,GO:0005845,GO:0005844,GO:0033391,GO:0007286,GO:0034587,GO:0003676,GO:0005737,GO:0043186,GO:0007283,GO:0007275,GO:0006417,GO:0031047,GO:0007126","protein binding,single-stranded RNA binding,mRNA binding,piRNA binding,mRNA cap binding complex,polysome,chromatoid body,spermatid development,piRNA metabolic process,nucleic acid binding,cytoplasm,P granule,spermatogenesis,multicellular organismal development,regulation of translation,gene silencing by RNA,meiosis","."]
["PIWIL2","piwi-like 2 (Drosophila) [Source:HGNC Symbol;Acc:17644]","ENSG00000197181","ENSP00000428267",2,"PAZ[1],Piwi[1]","family-412","PIWIL1,PIWIL2,PIWIL3,PIWIL4","PIWIL1","PIWIL2[39,35],PIWIL3[51,49],PIWIL4[49,50]","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0003729,GO:0034584,GO:0071546,GO:0043186,GO:0031047,GO:0045727,GO:0034587,GO:0000966","mRNA binding,piRNA binding,pi-body,P granule,gene silencing by RNA,positive regulation of translation,piRNA metabolic process,RNA 5'-end processing","GO:0005515,GO:0003676,GO:0003729,GO:0034584,GO:0005737,GO:0005844,GO:0071546,GO:0033391,GO:0043186,GO:0007275,GO:0007283,GO:0031047,GO:0048477,GO:0045727,GO:0007126,GO:0030718,GO:0034587,GO:0043046,GO:0060903,GO:0000966","protein binding,nucleic acid binding,mRNA binding,piRNA binding,cytoplasm,polysome,pi-body,chromatoid body,P granule,multicellular organismal development,spermatogenesis,gene silencing by RNA,oogenesis,positive regulation of translation,meiosis,germ-line stem cell maintenance,piRNA metabolic process,DNA methylation involved in gamete generation,positive regulation of meiosis I,RNA 5'-end processing","."]
["PIWIL3","piwi-like 3 (Drosophila) [Source:HGNC Symbol;Acc:18443]","ENSG00000184571","ENSP00000431843",2,"PAZ[1],Piwi[1]","family-412","PIWIL1,PIWIL2,PIWIL3,PIWIL4","PIWIL1","PIWIL2[39,35],PIWIL3[51,49],PIWIL4[49,50]","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0006417,GO:0031047","RNA binding,regulation of translation,gene silencing by RNA","GO:0005515,GO:0003676,GO:0003723,GO:0005737,GO:0030154,GO:0007275,GO:0007283,GO:0006417,GO:0031047,GO:0007126","protein binding,nucleic acid binding,RNA binding,cytoplasm,cell differentiation,multicellular organismal development,spermatogenesis,regulation of translation,gene silencing by RNA,meiosis","."]
["PIWIL4","piwi-like 4 (Drosophila) [Source:HGNC Symbol;Acc:18444]","ENSG00000134627","ENSP00000299001",2,"PAZ[1],Piwi[1]","family-412","PIWIL1,PIWIL2,PIWIL3,PIWIL4","PIWIL1","PIWIL2[39,35],PIWIL3[51,49],PIWIL4[49,50]","ncRNA","piRNA","established RBP ",".",".",".",".",".",".","GO:0034584,GO:0071547,GO:0031047,GO:0034587,GO:0043186,GO:0006417","piRNA binding,piP-body,gene silencing by RNA,piRNA metabolic process,P granule,regulation of translation","GO:0005515,GO:0003676,GO:0034584,GO:0005634,GO:0071547,GO:0007283,GO:0031047,GO:0034587,GO:0043046,GO:0005737,GO:0043186,GO:0030154,GO:0007275,GO:0006417,GO:0007126","protein binding,nucleic acid binding,piRNA binding,nucleus,piP-body,spermatogenesis,gene silencing by RNA,piRNA metabolic process,DNA methylation involved in gamete generation,cytoplasm,P granule,cell differentiation,multicellular organismal development,regulation of translation,meiosis","."]
["PEG10","paternally expressed 10 [Source:HGNC Symbol;Acc:14005]","ENSG00000242265","ENSP00000417587",2,"CCDC155[1],Retrotrans_gag[1]","family-413","PEG10,ZCCHC5,ZCCHC16","PEG10","ZCCHC5[28,19],ZCCHC16[19,20]","unknown","unknown","22658674, 22681889","candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005515,GO:0008270,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0001890,GO:0006915,GO:0030154,GO:0030512","protein binding,zinc ion binding,nucleic acid binding,DNA binding,nucleus,cytoplasm,placenta development,apoptotic process,cell differentiation,negative regulation of transforming growth factor beta receptor signaling pathway","."]
["ZCCHC5","zinc finger, CCHC domain containing 5 [Source:HGNC Symbol;Acc:22997]","ENSG00000179300","ENSP00000316794",1,"zf-CCHC[1]","family-413","PEG10,ZCCHC5,ZCCHC16","PEG10","ZCCHC5[28,19],ZCCHC16[19,20]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0008270,GO:0003676","zinc ion binding,nucleic acid binding","."]
["POP7","processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:19949]","ENSG00000172336","ENSP00000304353",1,"Rpp20[1]","family-414","POP7",".",".","ncRNA","MRP RNA","established RBP ","nuclease",".",".",1,".",".","GO:0004526,GO:0008033,GO:0005655","ribonuclease P activity,tRNA processing,nucleolar ribonuclease P complex","GO:0003676,GO:0004526,GO:0005634,GO:0008033,GO:0005515,GO:0005737,GO:0005655","nucleic acid binding,ribonuclease P activity,nucleus,tRNA processing,protein binding,cytoplasm,nucleolar ribonuclease P complex","."]
["FASTKD3","FAST kinase domains 3 [Source:HGNC Symbol;Acc:28758]","ENSG00000124279","ENSP00000264669",3,"FAST_1[1],FAST_2[1],RAP[1]","family-415","FASTK,FASTKD3,TBRG4","FASTK","FASTKD3[22,18],TBRG4[20,18]","mRNA","putative mRNA",15501674,".","novel",".",1,".",".",".",".","GO:0004672,GO:0005739,GO:0045333","protein kinase activity,mitochondrion,cellular respiration","."]
["TBRG4","transforming growth factor beta regulator 4 [Source:HGNC Symbol;Acc:17443]","ENSG00000136270","ENSP00000420597",3,"FAST_1[1],FAST_2[1],RAP[1]","family-415","FASTK,FASTKD3,TBRG4","FASTK","FASTKD3[22,18],TBRG4[20,18]","mRNA","putative mRNA","by homology","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005739,GO:0004672,GO:0008284,GO:0007050,GO:0045333,GO:0000080","mitochondrion,protein kinase activity,positive regulation of cell proliferation,cell cycle arrest,cellular respiration,mitotic G1 phase","."]
["FASTK","Fas-activated serine/threonine kinase [Source:HGNC Symbol;Acc:24676]","ENSG00000164896","ENSP00000297532",3,"FAST_1[1],FAST_2[1],RAP[1]","family-415","FASTK,FASTKD3,TBRG4","FASTK","FASTKD3[22,18],TBRG4[20,18]","mRNA","putative mRNA","established RBP ",".",".",".",".",".",".","GO:0043484","regulation of RNA splicing","GO:0016301,GO:0005515,GO:0005524,GO:0004674,GO:0004672,GO:0033867,GO:0005739,GO:0006468,GO:0043484,GO:0097190","kinase activity,protein binding,ATP binding,protein serine/threonine kinase activity,protein kinase activity,Fas-activated serine/threonine kinase activity,mitochondrion,protein phosphorylation,regulation of RNA splicing,apoptotic signaling pathway","."]
["TRMT13","tRNA methyltransferase 13 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25502]","ENSG00000122435","ENSP00000359160",3,"zf-TRM13_CCCH[1],zf-U11-48K[1],TRM13[1]","family-416","TRMT13",".",".","tRNA","tRNA","2'-O-methyltransferase; responsible for modification of tRNA at position 4; C-terminal domain has similarity to Rossmann-fold (RFM) superfamily of RNA methyltransferases",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0046872,GO:0008168,GO:0008033","metal ion binding,methyltransferase activity,tRNA processing","."]
["IREB2","iron-responsive element binding protein 2 [Source:HGNC Symbol;Acc:6115]","ENSG00000136381","ENSP00000258886",3,"Aconitase_C[1],Aconitase[2]","family-417","ACO1,IREB2","ACO1","IREB2[61,56]","mRNA","mRNA","ACO3",".",".",".",".",".",1,"GO:0006417,GO:0003723","regulation of translation,RNA binding","GO:0008152,GO:0051539,GO:0030350,GO:0005739,GO:0005829,GO:0007568,GO:0006417,GO:0009791,GO:0071456,GO:0030316,GO:0032526,GO:0006879,GO:0050892,GO:0006782,GO:0010040,GO:0034101,GO:0003723,GO:0005515,GO:0046872,GO:0005737,GO:0010468,GO:0006826","metabolic process,4 iron, 4 sulfur cluster binding,iron-responsive element binding,mitochondrion,cytosol,aging,regulation of translation,post-embryonic development,cellular response to hypoxia,osteoclast differentiation,response to retinoic acid,cellular iron ion homeostasis,intestinal absorption,protoporphyrinogen IX biosynthetic process,response to iron(II) ion,erythrocyte homeostasis,RNA binding,protein binding,metal ion binding,cytoplasm,regulation of gene expression,iron ion transport","."]
["ACO1","aconitase 1, soluble [Source:HGNC Symbol;Acc:117]","ENSG00000122729","ENSP00000438733",2,"Aconitase_C[1],Aconitase[1]","family-417","ACO1,IREB2","ACO1","IREB2[61,56]","mRNA","mRNA","The protein encoded by this gene is a bifunctional, cytosolic protein that functions as an essential enzyme in the TCA cycle and interacts with mRNA to control the levels of iron inside cells. When cellular iron levels are high, this protein binds to a 4Fe-4S cluster and functions as an aconitase. Aconitases are iron-sulfur proteins that function to catalyze the conversion of citrate to isocitrate. When cellular iron levels are low, the protein binds to iron-responsive elements (IREs), which are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. When the protein binds to IRE, it results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degraded transferrin receptor mRNA. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jan 2014]",".",".",".",".",".",1,"GO:0006417,GO:0003723","regulation of translation,RNA binding","GO:0051539,GO:0005737,GO:0005739,GO:0005829,GO:0006417,GO:0008152,GO:0009791,GO:0006879,GO:0050892,GO:0003723,GO:0005515,GO:0046872,GO:0003994,GO:0030350,GO:0005783,GO:0005794,GO:0010468,GO:0006099,GO:0006101,GO:0010040","4 iron, 4 sulfur cluster binding,cytoplasm,mitochondrion,cytosol,regulation of translation,metabolic process,post-embryonic development,cellular iron ion homeostasis,intestinal absorption,RNA binding,protein binding,metal ion binding,aconitate hydratase activity,iron-responsive element binding,endoplasmic reticulum,Golgi apparatus,regulation of gene expression,tricarboxylic acid cycle,citrate metabolic process,response to iron(II) ion","."]
["ZCCHC3","zinc finger, CCHC domain containing 3 [Source:HGNC Symbol;Acc:16230]","ENSG00000177764","ENSP00000371789",1,"zf-CCHC[1]","family-418","ZCCHC3",".",".","unknown","unknown","established RBP ","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0008270,GO:0003676","zinc ion binding,nucleic acid binding","."]
["SNUPN","snurportin 1 [Source:HGNC Symbol;Acc:14245]","ENSG00000169371","ENSP00000309831",1,"Snurportin1[1]","family-419","SNUPN",".",".","snRNA","snRNA","The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0000339,GO:0016070,GO:0061015,GO:0000387,GO:0034660","RNA cap binding,RNA metabolic process,snRNA import into nucleus,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005515,GO:0008565,GO:0000339,GO:0005634,GO:0005737,GO:0005829,GO:0005643,GO:0010467,GO:0016070,GO:0006606,GO:0061015,GO:0000387,GO:0034660","protein binding,protein transporter activity,RNA cap binding,nucleus,cytoplasm,cytosol,nuclear pore,gene expression,RNA metabolic process,protein import into nucleus,snRNA import into nucleus,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["PTRHD1","peptidyl-tRNA hydrolase domain containing 1 [Source:HGNC Symbol;Acc:33782]","ENSG00000184924","ENSP00000330389",1,"PTH2[1]","family-42","PTRHD1",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004045","aminoacyl-tRNA hydrolase activity","GO:0004725,GO:0004045","protein tyrosine phosphatase activity,aminoacyl-tRNA hydrolase activity","."]
["HARS","histidyl-tRNA synthetase [Source:HGNC Symbol;Acc:4816]","ENSG00000170445","ENSP00000411085",3,"HGTP_anticodon[1],tRNA-synt_His[1],WHEP-TRS[1]","family-420","HARS,HARS2","HARS","HARS2[72,72]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0006418,GO:0004821,GO:0006412,GO:0006427","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,histidine-tRNA ligase activity,translation,histidyl-tRNA aminoacylation","GO:0005737,GO:0005524,GO:0004812,GO:0006418,GO:0000166,GO:0004821,GO:0005829,GO:0006412,GO:0010467,GO:0006427","cytoplasm,ATP binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,nucleotide binding,histidine-tRNA ligase activity,cytosol,translation,gene expression,histidyl-tRNA aminoacylation"," USHER SYNDROME, TYPE IIIB; USH3B"]
["HARS2","histidyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:4817]","ENSG00000112855","ENSP00000230771",2,"HGTP_anticodon[1],tRNA-synt_His[1]","family-420","HARS,HARS2","HARS","HARS2[72,72]","tRNA","tRNA","established RBP ","candidate mRNA binder",".",".",1,".",".","GO:0004812,GO:0006418,GO:0004821,GO:0006427,GO:0006412","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,histidine-tRNA ligase activity,histidyl-tRNA aminoacylation,translation","GO:0005737,GO:0000166,GO:0005524,GO:0004812,GO:0006418,GO:0004821,GO:0006427,GO:0005739,GO:0005759,GO:0006412,GO:0010467","cytoplasm,nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,histidine-tRNA ligase activity,histidyl-tRNA aminoacylation,mitochondrion,mitochondrial matrix,translation,gene expression"," PERRAULT SYNDROME 2; PRLTS2"]
["HNRNPK","heterogeneous nuclear ribonucleoprotein K [Source:HGNC Symbol;Acc:5044]","ENSG00000165119","ENSP00000365458",4,"ROKNT[1],KH_1[3]","family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","HNRNPK","PCBP3[23,29],PCBP4[20,24],PCBP2[25,31],PCBP1[22,29]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0071013,GO:0008380,GO:0000398,GO:0006396","RNA binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0003723,GO:0005515,GO:0000978,GO:0003697,GO:0001077,GO:0005634,GO:0005737,GO:0042995,GO:0002102,GO:0030054,GO:0005654,GO:0000790,GO:0071013,GO:0045944,GO:0042981,GO:0007165,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0019048,GO:0048260,GO:0010988,GO:0045716,GO:0072369","RNA binding,protein binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,single-stranded DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription,nucleus,cytoplasm,cell projection,podosome,cell junction,nucleoplasm,nuclear chromatin,catalytic step 2 spliceosome,positive regulation of transcription from RNA polymerase II promoter,regulation of apoptotic process,signal transduction,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,modulation by virus of host morphology or physiology,positive regulation of receptor-mediated endocytosis,regulation of low-density lipoprotein particle clearance,positive regulation of low-density lipoprotein particle receptor biosynthetic process,regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter","."]
["PCBP1","poly(rC) binding protein 1 [Source:HGNC Symbol;Acc:8647]","ENSG00000169564","ENSP00000305556",3,"KH_1[3]","family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","HNRNPK","PCBP3[23,29],PCBP4[20,24],PCBP2[25,31],PCBP1[22,29]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0016071,GO:0008380,GO:0000398","RNA binding,ribonucleoprotein complex,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome","GO:0005515,GO:0003723,GO:0003697,GO:0005634,GO:0005737,GO:0005654,GO:0030529,GO:0010467,GO:0016071,GO:0008380,GO:0000398","protein binding,RNA binding,single-stranded DNA binding,nucleus,cytoplasm,nucleoplasm,ribonucleoprotein complex,gene expression,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome","."]
["PCBP2","poly(rC) binding protein 2 [Source:HGNC Symbol;Acc:8648]","ENSG00000197111","ENSP00000394116",3,"KH_1[3]","family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","HNRNPK","PCBP3[23,29],PCBP4[20,24],PCBP2[25,31],PCBP1[22,29]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0016071,GO:0008380,GO:0000398","RNA binding,ribonucleoprotein complex,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome","GO:0003723,GO:0005634,GO:0005737,GO:0005515,GO:0003677,GO:0031625,GO:0019899,GO:0005829,GO:0005654,GO:0030529,GO:0045087,GO:0010467,GO:0016071,GO:0008380,GO:0000398,GO:0032480,GO:0043161,GO:0051607,GO:0050687","RNA binding,nucleus,cytoplasm,protein binding,DNA binding,ubiquitin protein ligase binding,enzyme binding,cytosol,nucleoplasm,ribonucleoprotein complex,innate immune response,gene expression,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,negative regulation of type I interferon production,proteasome-mediated ubiquitin-dependent protein catabolic process,defense response to virus,negative regulation of defense response to virus","."]
["PCBP3","poly(rC) binding protein 3 [Source:HGNC Symbol;Acc:8651]","ENSG00000183570","ENSP00000383165",3,"KH_1[3]","family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","HNRNPK","PCBP3[23,29],PCBP4[20,24],PCBP2[25,31],PCBP1[22,29]","mRNA","mRNA","established RBP ",".","RNAbinding",".",1,1,1,"GO:0003723,GO:0030529,GO:0016071","RNA binding,ribonucleoprotein complex,mRNA metabolic process","GO:0003723,GO:0003677,GO:0005634,GO:0005739,GO:0005829,GO:0043231,GO:0030529,GO:0016071","RNA binding,DNA binding,nucleus,mitochondrion,cytosol,intracellular membrane-bounded organelle,ribonucleoprotein complex,mRNA metabolic process","."]
["PCBP4","poly(rC) binding protein 4 [Source:HGNC Symbol;Acc:8652]","ENSG00000090097","ENSP00000395030",3,"KH_1[3]","family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","HNRNPK","PCBP3[23,29],PCBP4[20,24],PCBP2[25,31],PCBP1[22,29]","mRNA","mRNA","established RBP ",".","RNAbinding",".",1,1,1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0003723,GO:0006977,GO:0007050,GO:0008630,GO:0003677,GO:0005737,GO:0030529","RNA binding,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,cell cycle arrest,intrinsic apoptotic signaling pathway in response to DNA damage,DNA binding,cytoplasm,ribonucleoprotein complex","."]
["AQR","aquarius homolog (mouse) [Source:HGNC Symbol;Acc:29513]","ENSG00000021776","ENSP00000156471",2,"AAA_11[1],AAA_12[1]","family-422","AQR",".",".","mRNA","mRNA",16949364,"RNAbinding","experimentally validated",1,1,1,".","GO:0097157,GO:0005681,GO:0000398,GO:0071013","pre-mRNA intronic binding,spliceosomal complex,mRNA splicing, via spliceosome,catalytic step 2 spliceosome","GO:0097157,GO:0005681,GO:0000398,GO:0005515,GO:0071013","pre-mRNA intronic binding,spliceosomal complex,mRNA splicing, via spliceosome,protein binding,catalytic step 2 spliceosome","."]
["ICT1","immature colon carcinoma transcript 1 [Source:HGNC Symbol;Acc:5359]","ENSG00000167862","ENSP00000301585",1,"RF-1[1]","family-423","ICT1",".",".","tRNA","tRNA",20186120,".",".",".",".",".",".","GO:0004045,GO:0003747,GO:0016150,GO:0005762,GO:0006415,GO:0070126","aminoacyl-tRNA hydrolase activity,translation release factor activity,translation release factor activity, codon nonspecific,mitochondrial large ribosomal subunit,translational termination,mitochondrial translational termination","GO:0004045,GO:0003747,GO:0016150,GO:0005739,GO:0005762,GO:0006415,GO:0070126","aminoacyl-tRNA hydrolase activity,translation release factor activity,translation release factor activity, codon nonspecific,mitochondrion,mitochondrial large ribosomal subunit,translational termination,mitochondrial translational termination","."]
["UNK","unkempt homolog (Drosophila) [Source:HGNC Symbol;Acc:29369]","ENSG00000132478","ENSP00000293218",3,"DUF3450[1],zf-CCCH[1],zf-C3HC4_3[1]","family-424","UNK,UNKL","UNK","UNKL[47,56]","unknown","unknown","by homology","candidate mRNA binder","novel",1,1,".",1,".",".","GO:0008270,GO:0046872","zinc ion binding,metal ion binding","."]
["UNKL","unkempt homolog (Drosophila)-like [Source:HGNC Symbol;Acc:14184]","ENSG00000059145","ENSP00000373873",2,"zf-CCCH[1],zf-C3HC4_3[1]","family-424","UNK,UNKL","UNK","UNKL[47,56]","unknown","unknown","by homology",".",".",".",".",".",1,".",".","GO:0005515,GO:0008270,GO:0016874,GO:0046872,GO:0005634,GO:0005737,GO:0016567","protein binding,zinc ion binding,ligase activity,metal ion binding,nucleus,cytoplasm,protein ubiquitination","."]
["CEBPZ","CCAAT/enhancer binding protein (C/EBP), zeta [Source:HGNC Symbol;Acc:24218]","ENSG00000115816","ENSP00000234170",1,"CBF[1]","family-425","CEBPZ",".",".","rRNA","putative rRNA","MAK21 yeast homolog","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0005488,GO:0003677,GO:0005634,GO:0006366,GO:0006355","binding,DNA binding,nucleus,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent","."]
["MRPS9","mitochondrial ribosomal protein S9 [Source:HGNC Symbol;Acc:14501]","ENSG00000135972","ENSP00000258455",1,"Ribosomal_S9[1]","family-426","MRPS9",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation","GO:0005515,GO:0003735,GO:0005739,GO:0005840,GO:0005763,GO:0006412,GO:0043043,GO:0042769","protein binding,structural constituent of ribosome,mitochondrion,ribosome,mitochondrial small ribosomal subunit,translation,peptide biosynthetic process,DNA damage response, detection of DNA damage","."]
["THG1L","tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) [Source:HGNC Symbol;Acc:26053]","ENSG00000113272","ENSP00000231198",2,"Thg1[1],Thg1C[1]","family-427","THG1L",".",".","tRNA","putative tRNA","tRNAHis guanylyltransferase; adds a guanosine residue to the 5' end of tRNAH is after transcription and RNase P cleavage; can also catalyze reverse (3'-5') polymerization with certain substrates in a template-dependent reaction; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes.",".",".",".",".",".",".","GO:0008193,GO:0006400,GO:0000049,GO:0008033","tRNA guanylyltransferase activity,tRNA modification,tRNA binding,tRNA processing","GO:0000287,GO:0008193,GO:0006400,GO:0005524,GO:0005525,GO:0000049,GO:0042802,GO:0005737,GO:0005739,GO:0008033,GO:0051289","magnesium ion binding,tRNA guanylyltransferase activity,tRNA modification,ATP binding,GTP binding,tRNA binding,identical protein binding,cytoplasm,mitochondrion,tRNA processing,protein homotetramerization","."]
["ZCCHC13","zinc finger, CCHC domain containing 13 [Source:HGNC Symbol;Acc:31749]","ENSG00000187969","ENSP00000345633",4,"zf-CCHC[4]","family-428","CNBP,ZCCHC13","CNBP","ZCCHC13[56,61]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".","GO:0008270,GO:0003676","zinc ion binding,nucleic acid binding","."]
["CNBP","CCHC-type zinc finger, nucleic acid binding protein [Source:HGNC Symbol;Acc:13164]","ENSG00000169714","ENSP00000410769",7,"zf-CCHC[7]","family-428","CNBP,ZCCHC13","CNBP","ZCCHC13[56,61]","mRNA","mRNA","This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","RNAbinding","RNAbinding",1,1,1,".","GO:0003727","single-stranded RNA binding","GO:0008270,GO:0003676,GO:0003700,GO:0003727,GO:0003697,GO:0005634,GO:0005783,GO:0005829,GO:0045944,GO:0045893,GO:0008284,GO:0006351,GO:0006355,GO:0006695","zinc ion binding,nucleic acid binding,sequence-specific DNA binding transcription factor activity,single-stranded RNA binding,single-stranded DNA binding,nucleus,endoplasmic reticulum,cytosol,positive regulation of transcription from RNA polymerase II promoter,positive regulation of transcription, DNA-dependent,positive regulation of cell proliferation,transcription, DNA-templated,regulation of transcription, DNA-dependent,cholesterol biosynthetic process"," MYOTONIC DYSTROPHY 2; DM2"]
["SRRT","serrate RNA effector molecule homolog (Arabidopsis) [Source:HGNC Symbol;Acc:24101]","ENSG00000087087","ENSP00000391852",2,"ARS2[1],DUF3546[1]","family-429","SRRT",".",".","ncRNA","miRNA / mRNA","19632182, 22244333","RNAbinding","RNArelated",1,1,1,1,"GO:0031053","primary miRNA processing","GO:0005515,GO:0003677,GO:0005737,GO:0005654,GO:0006355,GO:0008283,GO:0097150,GO:0031053,GO:0006351,GO:0046685","protein binding,DNA binding,cytoplasm,nucleoplasm,regulation of transcription, DNA-dependent,cell proliferation,neuronal stem cell maintenance,primary miRNA processing,transcription, DNA-templated,response to arsenic-containing substance","."]
["CD2BP2","CD2 (cytoplasmic tail) binding protein 2 [Source:HGNC Symbol;Acc:1656]","ENSG00000169217","ENSP00000304903",1,"GYF[1]","family-43","CD2BP2",".",".","snRNA","snRNA",15840814,".",".",".",".",".",".","GO:0043021,GO:0005682,GO:0008380,GO:0000398","ribonucleoprotein complex binding,U5 snRNP,RNA splicing,mRNA splicing, via spliceosome","GO:0005515,GO:0043021,GO:0005634,GO:0005737,GO:0005654,GO:0016607,GO:0005682,GO:0010467,GO:0008380,GO:0000398,GO:0010923,GO:0000244","protein binding,ribonucleoprotein complex binding,nucleus,cytoplasm,nucleoplasm,nuclear speck,U5 snRNP,gene expression,RNA splicing,mRNA splicing, via spliceosome,negative regulation of phosphatase activity,spliceosomal tri-snRNP complex assembly","."]
["SNRPG","small nuclear ribonucleoprotein polypeptide G [Source:HGNC Symbol;Acc:11163]","ENSG00000143977","ENSP00000272348",1,"LSM[1]","family-430","SNRPG",".",".","snRNA","snRNA","established RBP ",".","RNAbinding",".",1,".",1,"GO:0003723,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0016070,GO:0008380,GO:0000398,GO:0000245,GO:0031124,GO:0000387,GO:0034660,GO:0008334","RNA binding,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,histone mRNA metabolic process","GO:0003723,GO:0005515,GO:0005829,GO:0005654,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0006366,GO:0010467,GO:0016070,GO:0008380,GO:0000398,GO:0000245,GO:0031124,GO:0000387,GO:0034660,GO:0006369,GO:0008334","RNA binding,protein binding,cytosol,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["APTX","aprataxin [Source:HGNC Symbol;Acc:15984]","ENSG00000137074","ENSP00000369141",2,"FHA[1],DcpS_C[1]","family-431","APTX",".",".","diverse","RNA/DNA",24362567,".",".",".",".",".",1,"GO:0003725","double-stranded RNA binding","GO:0005515,GO:0046872,GO:0003690,GO:0003725,GO:0003682,GO:0008967,GO:0003684,GO:0047485,GO:0051219,GO:0033699,GO:0046403,GO:0005737,GO:0005730,GO:0005654,GO:0000785,GO:0000790,GO:0006974,GO:0042542,GO:0006302,GO:0008219,GO:0031647,GO:0000012,GO:0006266,GO:0098506,GO:0003824","protein binding,metal ion binding,double-stranded DNA binding,double-stranded RNA binding,chromatin binding,phosphoglycolate phosphatase activity,damaged DNA binding,protein N-terminus binding,phosphoprotein binding,DNA 5'-adenosine monophosphate hydrolase activity,polynucleotide 3'-phosphatase activity,cytoplasm,nucleolus,nucleoplasm,chromatin,nuclear chromatin,cellular response to DNA damage stimulus,response to hydrogen peroxide,double-strand break repair,cell death,regulation of protein stability,single strand break repair,DNA ligation,polynucleotide 3' dephosphorylation,catalytic activity"," ATAXIA, EARLY-ONSET, WITH OCULOMOTOR APRAXIA AND HYPOALBUMINEMIA;"]
["RPL17","ribosomal protein L17 [Source:HGNC Symbol;Acc:10307]","ENSG00000265681","ENSP00000463885",1,"Ribosomal_L22[1]","family-432","RPL17",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0022625,GO:0015934,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005829,GO:0005840,GO:0022625,GO:0015934,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytosol,ribosome,cytosolic large ribosomal subunit,large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["BMS1","BMS1 homolog, ribosome assembly protein (yeast) [Source:HGNC Symbol;Acc:23505]","ENSG00000165733","ENSP00000363642",3,"MobB[1],DUF663[1],AARP2CN[1]","family-433","BMS1",".",".","rRNA","rRNA","established RBP ","candidate mRNA binder","novel",1,1,1,".","GO:0042254,GO:0042255","ribosome biogenesis,ribosome assembly","GO:0005524,GO:0005525,GO:0003924,GO:0005634,GO:0005730,GO:0042254,GO:0042255","ATP binding,GTP binding,GTPase activity,nucleus,nucleolus,ribosome biogenesis,ribosome assembly","."]
["SARS","seryl-tRNA synthetase [Source:HGNC Symbol;Acc:10537]","ENSG00000031698","ENSP00000358939",2,"tRNA-synt_2b[1],Seryl_tRNA_N[1]","family-434","SARS,SARS2","SARS","SARS2[22,22]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004828,GO:0006418,GO:0006434,GO:0003723,GO:0006412,GO:0008033","aminoacyl-tRNA ligase activity,serine-tRNA ligase activity,tRNA aminoacylation for protein translation,seryl-tRNA aminoacylation,RNA binding,translation,tRNA processing","GO:0000166,GO:0005524,GO:0004812,GO:0004828,GO:0005737,GO:0006418,GO:0006434,GO:0003723,GO:0005739,GO:0005829,GO:0006412,GO:0010467,GO:0008033,GO:0097056","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,serine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,seryl-tRNA aminoacylation,RNA binding,mitochondrion,cytosol,translation,gene expression,tRNA processing,selenocysteinyl-tRNA(Sec) biosynthetic process","."]
["SARS2","Serine--tRNA ligase, mitochondrial  [Source:UniProtKB/TrEMBL;Acc:E7EX87]","ENSG00000269547","ENSP00000472465",2,"tRNA-synt_2b[1],FBA[1]","family-434","SARS,SARS2","SARS","SARS2[22,22]","tRNA","tRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0004812,GO:0004828,GO:0006418,GO:0006434","aminoacyl-tRNA ligase activity,serine-tRNA ligase activity,tRNA aminoacylation for protein translation,seryl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004828,GO:0005737,GO:0030163,GO:0006418,GO:0006434,GO:0005739,GO:0005759,GO:0010467,GO:0097056","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,serine-tRNA ligase activity,cytoplasm,protein catabolic process,tRNA aminoacylation for protein translation,seryl-tRNA aminoacylation,mitochondrion,mitochondrial matrix,gene expression,selenocysteinyl-tRNA(Sec) biosynthetic process"," HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS"]
["PAIP2","poly(A) binding protein interacting protein 2 [Source:HGNC Symbol;Acc:17970]","ENSG00000120727","ENSP00000378275",1,"PAM2[1]","family-435","PAIP2,PAIP2B","PAIP2","PAIP2B[58,60]","mRNA","mRNA",15175342,".",".",".",".",".",".","GO:0030371","translation repressor activity","GO:0005515,GO:0030371,GO:0005737,GO:0045947","protein binding,translation repressor activity,cytoplasm,negative regulation of translational initiation","."]
["PAIP2B","poly(A) binding protein interacting protein 2B [Source:HGNC Symbol;Acc:29200]","ENSG00000124374","ENSP00000244221",1,"PAM2[1]","family-435","PAIP2,PAIP2B","PAIP2","PAIP2B[58,60]","mRNA","mRNA",20739757,".",".",".",".",".",".","GO:0000900","translation repressor activity, nucleic acid binding","GO:0005515,GO:0000900,GO:0005737,GO:0045947","protein binding,translation repressor activity, nucleic acid binding,cytoplasm,negative regulation of translational initiation","."]
["GEMIN4","gem (nuclear organelle) associated protein 4 [Source:HGNC Symbol;Acc:15717] [Type: protein coding Ensembl/Havana merge]","ENSG00000179409","ENSP00000321706",".",".","family-436","GEMIN4",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005681,GO:0030532,GO:0016070,GO:0006364,GO:0000387,GO:0034660","spliceosomal complex,small nuclear ribonucleoprotein complex,RNA metabolic process,rRNA processing,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005515,GO:0005737,GO:0005829,GO:0005730,GO:0005654,GO:0005681,GO:0030532,GO:0097504,GO:0010467,GO:0016070,GO:0006364,GO:0000387,GO:0034660","protein binding,cytoplasm,cytosol,nucleolus,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,Gemini of coiled bodies,gene expression,RNA metabolic process,rRNA processing,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["PNRC2","proline-rich nuclear receptor coactivator 2 [Source:HGNC Symbol;Acc:23158]","ENSG00000189266","ENSP00000334840",1,"PNRC[1]","family-437","PNRC1,PNRC2,PNRC2","PNRC1","PNRC2[16,37],PNRC2[16,37]","mRNA","mRNA",23085078,".",".",".",".",".",".","GO:0000932,GO:0000184,GO:0031087","cytoplasmic mRNA processing body,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,deadenylation-independent decapping of nuclear-transcribed mRNA","GO:0005515,GO:0005634,GO:0000932,GO:0006351,GO:0006355,GO:0000184,GO:0031087","protein binding,nucleus,cytoplasmic mRNA processing body,transcription, DNA-templated,regulation of transcription, DNA-dependent,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,deadenylation-independent decapping of nuclear-transcribed mRNA","."]
["FASTKD2","FAST kinase domains 2 [Source:HGNC Symbol;Acc:29160]","ENSG00000118246","ENSP00000236980",3,"FAST_1[1],FAST_2[1],RAP[1]","family-438","FASTKD2",".",".","mRNA","putative mRNA",15501674,"candidate mRNA binder","novel",1,1,1,".",".",".","GO:0004672,GO:0005739,GO:0045333","protein kinase activity,mitochondrion,cellular respiration","."]
["GEMIN6","gem (nuclear organelle) associated protein 6 [Source:HGNC Symbol;Acc:20044]","ENSG00000152147","ENSP00000387191",1,"Gemin6[1]","family-439","GEMIN6",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0000245,GO:0005681,GO:0016070,GO:0000398,GO:0000387,GO:0034660","spliceosomal complex assembly,spliceosomal complex,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005634,GO:0000245,GO:0005515,GO:0005737,GO:0005829,GO:0005654,GO:0005681,GO:0016604,GO:0097504,GO:0010467,GO:0016070,GO:0000398,GO:0000387,GO:0034660","nucleus,spliceosomal complex assembly,protein binding,cytoplasm,cytosol,nucleoplasm,spliceosomal complex,nuclear body,Gemini of coiled bodies,gene expression,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["DDX20","DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Source:HGNC Symbol;Acc:2743]","ENSG00000064703","ENSP00000358716",2,"Helicase_C[1],DEAD[1]","family-44","DDX20,DDX39B,DDX39A","DDX20","DDX39B[17,33],DDX39A[17,32]","snRNA","snRNA/mRNA","22445758 This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0004004,GO:0005681,GO:0016070,GO:0006396,GO:0000387,GO:0034660","ATP-dependent RNA helicase activity,spliceosomal complex,RNA metabolic process,RNA processing,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005524,GO:0003676,GO:0008026,GO:0005515,GO:0019904,GO:0003677,GO:0004386,GO:0004004,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0005654,GO:0005681,GO:0017053,GO:0097504,GO:0043065,GO:0048477,GO:0050810,GO:0045892,GO:0000122,GO:0010467,GO:0016070,GO:0006396,GO:0000244,GO:0000387,GO:0034660","ATP binding,nucleic acid binding,ATP-dependent helicase activity,protein binding,protein domain specific binding,DNA binding,helicase activity,ATP-dependent RNA helicase activity,nucleus,cytoplasm,cytosol,cytoskeleton,nucleoplasm,spliceosomal complex,transcriptional repressor complex,Gemini of coiled bodies,positive regulation of apoptotic process,oogenesis,regulation of steroid biosynthetic process,negative regulation of transcription, DNA-dependent,negative regulation of transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA processing,spliceosomal tri-snRNP complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["DDX39A","DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A [Source:HGNC Symbol;Acc:17821]","ENSG00000123136","ENSP00000242776",2,"Helicase_C[1],DEAD[1]","family-44","DDX20,DDX39B,DDX39A","DDX20","DDX39B[17,33],DDX39A[17,32]","mRNA","mRNA","established RBP ","helicase","RNArelated",1,1,".",".","GO:0000398,GO:0006406","mRNA splicing, via spliceosome,mRNA export from nucleus","GO:0005524,GO:0003676,GO:0008026,GO:0003677,GO:0016787,GO:0005515,GO:0004386,GO:0005634,GO:0005737,GO:0000398,GO:0006406","ATP binding,nucleic acid binding,ATP-dependent helicase activity,DNA binding,hydrolase activity,protein binding,helicase activity,nucleus,cytoplasm,mRNA splicing, via spliceosome,mRNA export from nucleus","."]
["DDX39B","DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B [Source:HGNC Symbol;Acc:13917]","ENSG00000237889","ENSP00000406348",2,"Helicase_C[1],DEAD[1]","family-44","DDX20,DDX39B,DDX39A","DDX20","DDX39B[17,33],DDX39A[17,32]","mRNA","mRNA","established RBP ","helicase","RNAbinding",1,1,1,".","GO:0017070,GO:0004004,GO:0008186,GO:0030621,GO:0005681,GO:0005687,GO:0005688,GO:0008380,GO:0000398,GO:0006406,GO:0000245,GO:0010501","U6 snRNA binding,ATP-dependent RNA helicase activity,RNA-dependent ATPase activity,U4 snRNA binding,spliceosomal complex,U4 snRNP,U6 snRNP,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,spliceosomal complex assembly,RNA secondary structure unwinding","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0004386,GO:0005515,GO:0043008,GO:0017070,GO:0004004,GO:0008186,GO:0030621,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0000346,GO:0005687,GO:0005688,GO:0008380,GO:0000398,GO:0006406,GO:0000245,GO:0032786,GO:0010501,GO:2000002,GO:0046784","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,protein binding,ATP-dependent protein binding,U6 snRNA binding,ATP-dependent RNA helicase activity,RNA-dependent ATPase activity,U4 snRNA binding,nucleus,cytoplasm,spliceosomal complex,nuclear speck,transcription export complex,U4 snRNP,U6 snRNP,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,spliceosomal complex assembly,positive regulation of DNA-dependent transcription, elongation,RNA secondary structure unwinding,negative regulation of DNA damage checkpoint,viral mRNA export from host cell nucleus","."]
["DHX37","DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Source:HGNC Symbol;Acc:17210]","ENSG00000150990","ENSP00000311135",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-440","DHX37",".",".","snoRNA","putative snoRNA","ECM16",".",".",".",".",".",".",".",".","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0006810","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,transport","."]
["ZNF346","zinc finger protein 346 [Source:HGNC Symbol;Acc:16403]","ENSG00000113761","ENSP00000350869",4,"zf-met[4]","family-441","ZMAT1,KRCC1,ZNF346,ZMAT4","ZMAT1","KRCC1[27,66],ZNF346[10,21],ZMAT4[10,28]","unknown","unknown","established RBP ","RNAbinding",".",".",1,".",".","GO:0003725","double-stranded RNA binding","GO:0005515,GO:0008270,GO:0003676,GO:0003725,GO:0005634,GO:0005737,GO:0005730,GO:0006915,GO:0046872,GO:0043065","protein binding,zinc ion binding,nucleic acid binding,double-stranded RNA binding,nucleus,cytoplasm,nucleolus,apoptotic process,metal ion binding,positive regulation of apoptotic process","."]
["MRPL50","mitochondrial ribosomal protein L50 [Source:HGNC Symbol;Acc:16654]","ENSG00000136897","ENSP00000443844",1,"Ribosomal_L50[1]","family-442","MRPL50",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["RNASE1","ribonuclease, RNase A family, 1 (pancreatic) [Source:HGNC Symbol;Acc:10044]","ENSG00000129538","ENSP00000344193",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004522","pancreatic ribonuclease activity","GO:0005515,GO:0003676,GO:0016892,GO:0004522,GO:0005576","protein binding,nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,pancreatic ribonuclease activity,extracellular region","."]
["RNASE2","ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) [Source:HGNC Symbol;Acc:10045]","ENSG00000169385","ENSP00000303276",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004540,GO:0004522,GO:0006401","ribonuclease activity,pancreatic ribonuclease activity,RNA catabolic process","GO:0003676,GO:0004540,GO:0004522,GO:0005576,GO:0005764,GO:0006935,GO:0006401","nucleic acid binding,ribonuclease activity,pancreatic ribonuclease activity,extracellular region,lysosome,chemotaxis,RNA catabolic process","."]
["RNASE3","ribonuclease, RNase A family, 3 [Source:HGNC Symbol;Acc:10046]","ENSG00000169397","ENSP00000302324",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004540,GO:0006401","ribonuclease activity,RNA catabolic process","GO:0003676,GO:0004540,GO:0016892,GO:0005576,GO:0042742,GO:0006401","nucleic acid binding,ribonuclease activity,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region,defense response to bacterium,RNA catabolic process","."]
["RNASE4","ribonuclease, RNase A family, 4 [Source:HGNC Symbol;Acc:10047]","ENSG00000258818","ENSP00000307096",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004522,GO:0006379","pancreatic ribonuclease activity,mRNA cleavage","GO:0003676,GO:0004522,GO:0005576,GO:0006379","nucleic acid binding,pancreatic ribonuclease activity,extracellular region,mRNA cleavage","."]
["RNASE6","ribonuclease, RNase A family, k6 [Source:HGNC Symbol;Acc:10048]","ENSG00000169413","ENSP00000302046",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004540,GO:0006401","ribonuclease activity,RNA catabolic process","GO:0003676,GO:0004540,GO:0016892,GO:0005576,GO:0006952,GO:0006401","nucleic acid binding,ribonuclease activity,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region,defense response,RNA catabolic process","."]
["RNASE7","ribonuclease, RNase A family, 7 [Source:HGNC Symbol;Acc:19278]","ENSG00000165799","ENSP00000298690",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004540","ribonuclease activity","GO:0003676,GO:0004540,GO:0016892,GO:0005576,GO:0045087,GO:0042742,GO:0009617","nucleic acid binding,ribonuclease activity,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region,innate immune response,defense response to bacterium,response to bacterium","."]
["RNASE8","ribonuclease, RNase A family, 8 [Source:HGNC Symbol;Acc:19277]","ENSG00000173431","ENSP00000311398",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0004522","pancreatic ribonuclease activity","GO:0003676,GO:0004522,GO:0005576","nucleic acid binding,pancreatic ribonuclease activity,extracellular region","."]
["ANG","angiogenin, ribonuclease, RNase A family, 5 [Source:HGNC Symbol;Acc:483]","ENSG00000214274","ENSP00000336762",1,"RnaseA[1]","family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","ANG","RNASE7[31,29],RNASE6[28,27],RNASE8[28,27],RNASE3[29,27],RNASE4[41,41],RNASE1[37,35],RNASE2[27,24]","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0019843,GO:0004540,GO:0009303","rRNA binding,ribonuclease activity,rRNA transcription","GO:0005515,GO:0003677,GO:0004519,GO:0008201,GO:0003779,GO:0005507,GO:0005102,GO:0042277,GO:0019843,GO:0004540,GO:0016892,GO:0005634,GO:0005615,GO:0005730,GO:0043025,GO:0030426,GO:0005605,GO:0032311,GO:0001890,GO:0007154,GO:0001525,GO:0001666,GO:0001938,GO:0001541,GO:0001556,GO:0009725,GO:0048662,GO:0016477,GO:0030041,GO:0008219,GO:0017148,GO:0050714,GO:0032148,GO:0009303,GO:0007202,GO:0042592,GO:0042327,GO:0006651,GO:0032431","protein binding,DNA binding,endonuclease activity,heparin binding,actin binding,copper ion binding,receptor binding,peptide binding,rRNA binding,ribonuclease activity,endoribonuclease activity, producing 3'-phosphomonoesters,nucleus,extracellular space,nucleolus,neuronal cell body,growth cone,basal lamina,angiogenin-PRI complex,placenta development,cell communication,angiogenesis,response to hypoxia,positive regulation of endothelial cell proliferation,ovarian follicle development,oocyte maturation,response to hormone,negative regulation of smooth muscle cell proliferation,cell migration,actin filament polymerization,cell death,negative regulation of translation,positive regulation of protein secretion,activation of protein kinase B activity,rRNA transcription,activation of phospholipase C activity,homeostatic process,positive regulation of phosphorylation,diacylglycerol biosynthetic process,activation of phospholipase A2 activity"," AMYOTROPHIC LATERAL SCLEROSIS 9; ALS9"]
["DYNC1H1","dynein, cytoplasmic 1, heavy chain 1 [Source:HGNC Symbol;Acc:2961]","ENSG00000197102","ENSP00000348965",9,"Dynein_heavy[1],AAA_9[1],DHC_N1[1],DHC_N2[1],MT[1],AAA_6[1],AAA_5[1],AAA_7[1],AAA_8[1]","family-444","DNAH1,DNAH17,DNAH9,DYNC1H1,DNAH11,DYNC2H1,DNAH8,DNAH10,DNAH5,DNAH3,DNAH7,DNAH2,DNAH6","DNAH1","DNAH17[29,28],DNAH9[29,28],DYNC1H1[23,21],DNAH11[29,27],DYNC2H1[22,22],DNAH8[29,27],DNAH10[29,28],DNAH5[29,26],DNAH3[39,40],DNAH7[40,43],DNAH2[34,33],DNAH6[36,36]","mRNA","putative mRNA","22658674, 22681889","candidate mRNA binder","novel",1,1,".",".","GO:0033962","cytoplasmic mRNA processing body assembly","GO:0005515,GO:0000166,GO:0005524,GO:0016887,GO:0017111,GO:0042623,GO:0003777,GO:0005737,GO:0005829,GO:0005794,GO:0005874,GO:0005813,GO:0070062,GO:0005868,GO:0030286,GO:0034063,GO:0033962,GO:0000278,GO:0006810,GO:0000086,GO:0007018,GO:0008219,GO:0019886,GO:0007052","protein binding,nucleotide binding,ATP binding,ATPase activity,nucleoside-triphosphatase activity,ATPase activity, coupled,microtubule motor activity,cytoplasm,cytosol,Golgi apparatus,microtubule,centrosome,extracellular vesicular exosome,cytoplasmic dynein complex,dynein complex,stress granule assembly,cytoplasmic mRNA processing body assembly,mitotic cell cycle,transport,G2/M transition of mitotic cell cycle,microtubule-based movement,cell death,antigen processing and presentation of exogenous peptide antigen via MHC class II,mitotic spindle organization"," SPINAL MUSCULAR ATROPHY, LOWER EXTREMITY-PREDOMINANT, 1, AUTOSOMAL"]
["FTSJ3","FtsJ homolog 3 (E. coli) [Source:HGNC Symbol;Acc:17136]","ENSG00000108592","ENSP00000396673",3,"Spb1_C[1],FtsJ[1],DUF3381[1]","family-445","FTSJ3",".",".","rRNA","rRNA","SPB1 yeast homolog","RNAmod","RNArelated",1,1,".",".","GO:0008649,GO:0006364","rRNA methyltransferase activity,rRNA processing","GO:0008649,GO:0008168,GO:0032259,GO:0005515,GO:0005634,GO:0005730,GO:0006364","rRNA methyltransferase activity,methyltransferase activity,methylation,protein binding,nucleus,nucleolus,rRNA processing","."]
["SF3B2","splicing factor 3b, subunit 2, 145kDa [Source:HGNC Symbol;Acc:10769]","ENSG00000087365","ENSP00000318861",3,"SAP[1],DUF382[1],PSP[1]","family-446","SF3B2",".",".","mRNA","mRNA","This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,1,".","GO:0005681,GO:0005689,GO:0071013,GO:0006397,GO:0008380,GO:0000398","spliceosomal complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","GO:0003676,GO:0005515,GO:0005634,GO:0005654,GO:0005681,GO:0005689,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0019048","nucleic acid binding,protein binding,nucleus,nucleoplasm,spliceosomal complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,modulation by virus of host morphology or physiology","."]
["CTU2","cytosolic thiouridylase subunit 2 homolog (S. pombe) [Source:HGNC Symbol;Acc:28005]","ENSG00000174177","ENSP00000388320",1,"DUF2392[1]","family-447","CTU2",".",".","tRNA","tRNA","23874237, 18391219",".",".",".",".",".",".","GO:0000049,GO:0002098,GO:0034227,GO:0008033","tRNA binding,tRNA wobble uridine modification,tRNA thio-modification,tRNA processing","GO:0005515,GO:0000049,GO:0005737,GO:0005739,GO:0043234,GO:0002098,GO:0034227,GO:0008033","protein binding,tRNA binding,cytoplasm,mitochondrion,protein complex,tRNA wobble uridine modification,tRNA thio-modification,tRNA processing","."]
["XPOT","exportin, tRNA [Source:HGNC Symbol;Acc:12826]","ENSG00000184575","ENSP00000383722",1,"Xpo1[1]","family-448","XPOT",".",".","tRNA","tRNA","This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN. [provided by RefSeq, Jul 2008",".",".",".",".",".",".","GO:0000049,GO:0006409","tRNA binding,tRNA export from nucleus","GO:0005488,GO:0008536,GO:0005634,GO:0006886,GO:0000049,GO:0005737,GO:0005654,GO:0005643,GO:0006409","binding,Ran GTPase binding,nucleus,intracellular protein transport,tRNA binding,cytoplasm,nucleoplasm,nuclear pore,tRNA export from nucleus","."]
["RBMXL1","RNA binding motif protein, X-linked-like 1 [Source:HGNC Symbol;Acc:25073]","ENSG00000213516","ENSP00000318415",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",1,1,"GO:0003723,GO:0030529,GO:0006397,GO:0008380","RNA binding,ribonucleoprotein complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0030529,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,nucleus,ribonucleoprotein complex,mRNA processing,RNA splicing","."]
["RBMXL2","RNA binding motif protein, X-linked-like 2 [Source:HGNC Symbol;Acc:17886]","ENSG00000170748","ENSP00000304139",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",1,1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0030529","nucleotide binding,RNA binding,nucleic acid binding,nucleus,ribonucleoprotein complex","."]
["RBMXL3","RNA binding motif protein, X-linked-like 3 [Source:HGNC Symbol;Acc:26859]","ENSG00000175718","ENSP00000417451",1,"RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["RBMY1A1","RNA binding motif protein, Y-linked, family 1, member A1 [Source:HGNC Symbol;Acc:9912]","ENSG00000234414","ENSP00000303712",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003729,GO:0006397,GO:0008380,GO:0000381","mRNA binding,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","GO:0000166,GO:0005515,GO:0003676,GO:0003729,GO:0005634,GO:0006397,GO:0008380,GO:0000381","nucleotide binding,protein binding,nucleic acid binding,mRNA binding,nucleus,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","."]
["RBMY1B","RNA binding motif protein, Y-linked, family 1, member B [Source:HGNC Symbol;Acc:23914]","ENSG00000242875","ENSP00000372484",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005634,GO:0007283,GO:0006397,GO:0008380,GO:0008584","nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleus,spermatogenesis,mRNA processing,RNA splicing,male gonad development","."]
["RBMY1D","RNA binding motif protein, Y-linked, family 1, member D [Source:HGNC Symbol;Acc:23915]","ENSG00000244395","ENSP00000399181",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,RNA binding,nucleus,mRNA processing,RNA splicing","."]
["RBMY1E","RNA binding motif protein, Y-linked, family 1, member E [Source:HGNC Symbol;Acc:23916]","ENSG00000242389","ENSP00000372104",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,RNA binding,nucleus,mRNA processing,RNA splicing","."]
["RBMY1F","RNA binding motif protein, Y-linked, family 1, member F [Source:HGNC Symbol;Acc:23974]","ENSG00000169800","ENSP00000406005",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0007283,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,RNA binding,nucleus,spermatogenesis,mRNA processing,RNA splicing","."]
["RBMY1J","RNA binding motif protein, Y-linked, family 1, member J [Source:HGNC Symbol;Acc:23917]","ENSG00000226941","ENSP00000250831",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0007283,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,RNA binding,nucleus,spermatogenesis,mRNA processing,RNA splicing","."]
["RBMX","RNA binding motif protein, X-linked [Source:HGNC Symbol;Acc:9910]","ENSG00000147274","ENSP00000405117",2,"RBM1CTR[1],RRM_1[1]","family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","RBMX","RBMY1D[61,48],RBMY1J[61,48],RBMXL1[95,95],RBMY1A1[61,48],RBMXL2[74,74],RBMY1B[61,48],RBMY1F[61,48],RBMY1E[61,48],RBMXL3[57,21]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003727,GO:0005681,GO:0006376,GO:0003723,GO:0003729,GO:0071013,GO:0044530,GO:0008380,GO:0000381,GO:0000398,GO:0048026,GO:0048025","single-stranded RNA binding,spliceosomal complex,mRNA splice site selection,RNA binding,mRNA binding,catalytic step 2 spliceosome,supraspliceosomal complex,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,positive regulation of mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome","GO:0003727,GO:0005681,GO:0019013,GO:0045893,GO:0006376,GO:0000166,GO:0003676,GO:0005515,GO:0003723,GO:0001047,GO:0003682,GO:0003729,GO:0005634,GO:0005654,GO:0070062,GO:0005719,GO:0071013,GO:0044530,GO:0045944,GO:0006366,GO:0051260,GO:0010467,GO:0008380,GO:0000381,GO:0000398,GO:0071347,GO:0006509,GO:0048026,GO:0048025","single-stranded RNA binding,spliceosomal complex,viral nucleocapsid,positive regulation of transcription, DNA-dependent,mRNA splice site selection,nucleotide binding,nucleic acid binding,protein binding,RNA binding,core promoter binding,chromatin binding,mRNA binding,nucleus,nucleoplasm,extracellular vesicular exosome,nuclear euchromatin,catalytic step 2 spliceosome,supraspliceosomal complex,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,protein homooligomerization,gene expression,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,cellular response to interleukin-1,membrane protein ectodomain proteolysis,positive regulation of mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome","."]
["PPP1R10","protein phosphatase 1, regulatory subunit 10 [Source:HGNC Symbol;Acc:9284]","ENSG00000235291","ENSP00000389299",2,"zf-CCCH[1],Med26[1]","family-45","PPP1R10,PRR3","PPP1R10","PRR3[9,44]","unknown","unknown",12574161,"RNAbinding",".",".",1,1,1,"GO:0003723","RNA binding","GO:0003677,GO:0005634,GO:0006351,GO:0003723,GO:0046872,GO:0004864,GO:0000785,GO:0072357,GO:0006606,GO:0005515","DNA binding,nucleus,transcription, DNA-templated,RNA binding,metal ion binding,protein phosphatase inhibitor activity,chromatin,PTW/PP1 phosphatase complex,protein import into nucleus,protein binding","."]
["PRR3","proline rich 3 [Source:HGNC Symbol;Acc:21149]","ENSG00000206491","ENSP00000404669",1,"zf-CCCH[1]","family-45","PPP1R10,PRR3","PPP1R10","PRR3[9,44]","unknown","unknown","by homolohy","RNAbinding","novel",1,1,".",1,".",".","GO:0046872","metal ion binding","."]
["DKC1","dyskeratosis congenita 1, dyskerin [Source:HGNC Symbol;Acc:2890]","ENSG00000130826","ENSP00000358563",3,"PUA[1],DKCLD[1],TruB_N[1]","family-450","DKC1",".",".","snoRNA","snoRNA","established RBP ",".","RNAbinding",".",1,1,1,"GO:0003723,GO:0006396,GO:0009451,GO:0003720,GO:0005697,GO:0006364","RNA binding,RNA processing,RNA modification,telomerase activity,telomerase holoenzyme complex,rRNA processing","GO:0003723,GO:0009982,GO:0006396,GO:0001522,GO:0009451,GO:0005730,GO:0005515,GO:0003720,GO:0005634,GO:0005737,GO:0005654,GO:0015030,GO:0005697,GO:0008283,GO:0006364,GO:0000723,GO:0007004","RNA binding,pseudouridine synthase activity,RNA processing,pseudouridine synthesis,RNA modification,nucleolus,protein binding,telomerase activity,nucleus,cytoplasm,nucleoplasm,Cajal body,telomerase holoenzyme complex,cell proliferation,rRNA processing,telomere maintenance,telomere maintenance via telomerase"," DYSKERATOSIS CONGENITA, X-LINKED; DKCX"]
["MRPL17","mitochondrial ribosomal protein L17 [Source:HGNC Symbol;Acc:14053]","ENSG00000158042","ENSP00000288937",1,"Ribosomal_L17[1]","family-451","MRPL17",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0019904,GO:0005739,GO:0005743","structural constituent of ribosome,intracellular,ribosome,translation,protein domain specific binding,mitochondrion,mitochondrial inner membrane","."]
["TRA2A","transformer 2 alpha homolog (Drosophila) [Source:HGNC Symbol;Acc:16645]","ENSG00000164548","ENSP00000376290",1,"RRM_1[1]","family-452","TRA2A,TRA2B","TRA2A","TRA2B[68,67]","mRNA","mRNA","This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0000398","RNA binding,mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0005634,GO:0005515,GO:0003723,GO:0000398","nucleotide binding,nucleic acid binding,nucleus,protein binding,RNA binding,mRNA splicing, via spliceosome","."]
["TRA2B","transformer 2 beta homolog (Drosophila) [Source:HGNC Symbol;Acc:10781]","ENSG00000136527","ENSP00000371626",1,"RRM_1[1]","family-452","TRA2A,TRA2B","TRA2A","TRA2B[68,67]","mRNA","mRNA","This gene is a member of the transformer 2 homolog family and encodes a protein with several RRM (RNA recognition motif) domains. This phosphorylated nuclear protein binds to specific RNA sequences and plays a role in the regulation of pre-mRNA splicing. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003729,GO:0000381,GO:0000398,GO:0048026,GO:0000375","mRNA binding,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,positive regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0000166,GO:0005515,GO:0003729,GO:0005634,GO:0000381,GO:0000398,GO:0000302,GO:0048026,GO:0000375,GO:0003676","nucleotide binding,protein binding,mRNA binding,nucleus,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,response to reactive oxygen species,positive regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,nucleic acid binding","."]
["RPL26L1","ribosomal protein L26-like 1 [Source:HGNC Symbol;Acc:17050]","ENSG00000037241","ENSP00000265100",1,"KOW[1]","family-453","RPL26,RPL26L1","RPL26","RPL26L1[99,99]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0015934,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0015934,GO:0006412,GO:0005829,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,large ribosomal subunit,translation,cytosol,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL26","ribosomal protein L26 [Source:HGNC Symbol;Acc:10327]","ENSG00000161970","ENSP00000463784",1,"KOW[1]","family-453","RPL26,RPL26L1","RPL26","RPL26L1[99,99]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0015934,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,large ribosomal subunit,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0015934,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0005515","structural constituent of ribosome,large ribosomal subunit,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,protein binding"," DIAMOND-BLACKFAN ANEMIA 11; DBA11"]
["AUH","AU RNA binding protein/enoyl-CoA hydratase [Source:HGNC Symbol;Acc:890] [Type: protein coding Ensembl/Havana merge]","ENSG00000148090","ENSP00000364883",1,"ECH[1]","family-454","AUH,ECHDC3,ECHDC2,ECHS1,ECH1","AUH","ECHDC3[22,25],ECHDC2[46,53],ECHS1[26,31],ECH1[24,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003730,GO:0006402,GO:0003723","mRNA 3'-UTR binding,mRNA catabolic process,RNA binding","GO:0003824,GO:0008152,GO:0003730,GO:0004300,GO:0004490,GO:0005739,GO:0005759,GO:0044281,GO:0034641,GO:0006402,GO:0009083,GO:0006552,GO:0003723","catalytic activity,metabolic process,mRNA 3'-UTR binding,enoyl-CoA hydratase activity,methylglutaconyl-CoA hydratase activity,mitochondrion,mitochondrial matrix,small molecule metabolic process,cellular nitrogen compound metabolic process,mRNA catabolic process,branched-chain amino acid catabolic process,leucine catabolic process,RNA binding"," 3-@METHYLGLUTACONIC ACIDURIA, TYPE I; MGCA1"]
["EIF3C","eukaryotic translation initiation factor 3, subunit C [Source:HGNC Symbol;Acc:3279]","ENSG00000184110","ENSP00000378953",2,"eIF-3c_N[1],PCI[1]","family-455","EIF3C,EIF3CL","EIF3C","EIF3CL[100,100]","mRNA","mRNA",24092755,"translationfactor","novel",1,1,1,".","GO:0003743,GO:0031369,GO:0005852,GO:0016282,GO:0033290,GO:0006412,GO:0001731,GO:0006446,GO:0006413","translation initiation factor activity,translation initiation factor binding,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0005515,GO:0003743,GO:0031369,GO:0005829,GO:0005852,GO:0016282,GO:0033290,GO:0006412,GO:0010467,GO:0001731,GO:0006446,GO:0044267,GO:0006413,GO:0005488","protein binding,translation initiation factor activity,translation initiation factor binding,cytosol,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,gene expression,formation of translation preinitiation complex,regulation of translational initiation,cellular protein metabolic process,translational initiation,binding","."]
["EIF3CL","eukaryotic translation initiation factor 3, subunit C-like [Source:HGNC Symbol;Acc:26347]","ENSG00000205609","ENSP00000381916",2,"eIF-3c_N[1],PCI[1]","family-455","EIF3C,EIF3CL","EIF3C","EIF3CL[100,100]","mRNA","mRNA",24092755,".",".",".",".",".",".","GO:0003743,GO:0031369,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413","translation initiation factor activity,translation initiation factor binding,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0005515,GO:0003743,GO:0031369,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413","protein binding,translation initiation factor activity,translation initiation factor binding,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","."]
["SCAF8","SR-related CTD-associated factor 8 [Source:HGNC Symbol;Acc:20959]","ENSG00000213079","ENSP00000356154",2,"RRM_1[1],CTD_bind[1]","family-456","SCAF4,SCAF8","SCAF4","SCAF8[39,35]","mRNA","mRNA",18550522,".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380","RNA binding,spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0043175,GO:0005634,GO:0005681,GO:0016363,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,RNA polymerase core enzyme binding,nucleus,spliceosomal complex,nuclear matrix,mRNA processing,RNA splicing","."]
["SCAF4","SR-related CTD-associated factor 4 [Source:HGNC Symbol;Acc:19304]","ENSG00000156304","ENSP00000286835",2,"RRM_1[1],CTD_bind[1]","family-456","SCAF4,SCAF8","SCAF4","SCAF8[39,35]","mRNA","mRNA","This gene likely encodes a member of the arginine/serine-rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]","RNAbinding",".",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005634","nucleotide binding,RNA binding,nucleic acid binding,nucleus","."]
["EEF2K","eukaryotic elongation factor-2 kinase [Source:HGNC Symbol;Acc:24615]","ENSG00000103319","ENSP00000263026",1,"Alpha_kinase[1]","family-457","EEF2K",".",".","mRNA","putative mRNA","phosphorylates EEF2 thereby inhibiting translation",".",".",".",".",".",".","GO:0008135,GO:0006414","translation factor activity, nucleic acid binding,translational elongation","GO:0005524,GO:0004674,GO:0016772,GO:0006468,GO:0004686,GO:0005509,GO:0004672,GO:0005516,GO:0008135,GO:0005737,GO:0005829,GO:0008286,GO:0046777,GO:0031952,GO:0006414","ATP binding,protein serine/threonine kinase activity,transferase activity, transferring phosphorus-containing groups,protein phosphorylation,elongation factor-2 kinase activity,calcium ion binding,protein kinase activity,calmodulin binding,translation factor activity, nucleic acid binding,cytoplasm,cytosol,insulin receptor signaling pathway,protein autophosphorylation,regulation of protein autophosphorylation,translational elongation","."]
["RPL6","ribosomal protein L6 [Source:HGNC Symbol;Acc:10362]","ENSG00000089009","ENSP00000403172",2,"Ribosomal_L6e[1],Ribosomal_L6e_N[1]","family-458","RPL6",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0003677,GO:0005829,GO:0022625,GO:0006355,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,DNA binding,cytosol,cytosolic large ribosomal subunit,regulation of transcription, DNA-dependent,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["MRPL11","mitochondrial ribosomal protein L11 [Source:HGNC Symbol;Acc:14042]","ENSG00000174547","ENSP00000415356",2,"Ribosomal_L11[1],Ribosomal_L11_N[1]","family-459","MRPL11",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0005761,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial ribosome,translation","GO:0005515,GO:0003735,GO:0005840,GO:0005761,GO:0006412,GO:0005739","protein binding,structural constituent of ribosome,ribosome,mitochondrial ribosome,translation,mitochondrion","."]
["G3BP1","GTPase activating protein (SH3 domain) binding protein 1 [Source:HGNC Symbol;Acc:30292]","ENSG00000145907","ENSP00000348578",2,"RRM_1[1],NTF2[1]","family-46","G3BP1,G3BP2","G3BP1","G3BP2[66,64]","mRNA","mRNA","established RBP ","helicase","experimentally validated",1,1,1,1,"GO:0003729,GO:0010494,GO:0004004","mRNA binding,cytoplasmic stress granule,ATP-dependent RNA helicase activity","GO:0000166,GO:0003676,GO:0003729,GO:0010494,GO:0090090,GO:0005622,GO:0006810,GO:0005515,GO:0005524,GO:0003677,GO:0004519,GO:0004003,GO:0004004,GO:0005634,GO:0005886,GO:0005737,GO:0005829,GO:0007265","nucleotide binding,nucleic acid binding,mRNA binding,cytoplasmic stress granule,negative regulation of canonical Wnt signaling pathway,intracellular,transport,protein binding,ATP binding,DNA binding,endonuclease activity,ATP-dependent DNA helicase activity,ATP-dependent RNA helicase activity,nucleus,plasma membrane,cytoplasm,cytosol,Ras protein signal transduction","."]
["G3BP2","GTPase activating protein (SH3 domain) binding protein 2 [Source:HGNC Symbol;Acc:30291]","ENSG00000138757","ENSP00000352738",2,"RRM_1[1],NTF2[1]","family-46","G3BP1,G3BP2","G3BP1","G3BP2[66,64]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0051028","RNA binding,mRNA transport","GO:0005622,GO:0006810,GO:0005737,GO:0000166,GO:0003723,GO:0003676,GO:0030159,GO:0051028,GO:0007265,GO:0007253","intracellular,transport,cytoplasm,nucleotide binding,RNA binding,nucleic acid binding,receptor signaling complex scaffold activity,mRNA transport,Ras protein signal transduction,cytoplasmic sequestering of NF-kappaB","."]
["MRPS26","mitochondrial ribosomal protein S26 [Source:HGNC Symbol;Acc:14045]","ENSG00000125901","ENSP00000369682",1,"MRP-S26[1]","family-460","MRPS26",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0005763","mitochondrial small ribosomal subunit","GO:0005739,GO:0005763,GO:0043043,GO:0042769","mitochondrion,mitochondrial small ribosomal subunit,peptide biosynthetic process,DNA damage response, detection of DNA damage","."]
["SF3B5","splicing factor 3b, subunit 5, 10kDa [Source:HGNC Symbol;Acc:21083]","ENSG00000169976","ENSP00000356541",1,"SF3b10[1]","family-461","SF3B5",".",".","mRNA","mRNA",15146077,".",".",".",".",".",".","GO:0005689,GO:0008380,GO:0000398","U12-type spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome","GO:0005634,GO:0005654,GO:0005689,GO:0010467,GO:0008380,GO:0000398","nucleus,nucleoplasm,U12-type spliceosomal complex,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["DHX34","DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Source:HGNC Symbol;Acc:16719]","ENSG00000134815","ENSP00000331907",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-462","DHX34",".",".","mRNA","mRNA",23828042,"helicase",".",".",1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity","."]
["UTP23","UTP23, small subunit (SSU) processome component, homolog (yeast) [Source:HGNC Symbol;Acc:28224]","ENSG00000147679","ENSP00000349670",1,"Fcf1[1]","family-463","UTP23",".",".","snoRNA","snoRNA/rRNA","established RBP ",".","RNArelated",".",1,1,".","GO:0006364","rRNA processing","GO:0005730,GO:0032040,GO:0006364","nucleolus,small-subunit processome,rRNA processing","."]
["SNRNP48","small nuclear ribonucleoprotein 48kDa (U11/U12) [Source:HGNC Symbol;Acc:21368]","ENSG00000168566","ENSP00000339834",1,"zf-U11-48K[1]","family-464","SNRNP48",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005689,GO:0006397,GO:0008380","U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0046872,GO:0005634,GO:0005737,GO:0005689,GO:0006397,GO:0008380","metal ion binding,nucleus,cytoplasm,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["PRPF38B","PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Source:HGNC Symbol;Acc:25512]","ENSG00000134186","ENSP00000359042",1,"PRP38[1]","family-465","PRPF38B",".",".","snRNA","putative snRNA /mRNA","Unique component of the U4/U6.U5 tri-snRNP particle; tri-snRNP is required for conformational changes which result in the catalytic activation of the spliceosome; dispensable for spliceosome assembly",".","RNArelated",".",1,".",".","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","."]
["HEXIM1","hexamethylene bis-acetamide inducible 1 [Source:HGNC Symbol;Acc:24953]","ENSG00000186834","ENSP00000328773",1,"HEXIM[1]","family-466","HEXIM1,HEXIM2","HEXIM1","HEXIM2[33,42]","ncRNA","7SK RNA",14580347,".",".",".",".",1,".","GO:0017069","snRNA binding","GO:0005515,GO:0004861,GO:0017069,GO:0005634,GO:0005737,GO:0000122,GO:0006351,GO:0007507,GO:0045892,GO:0045736","protein binding,cyclin-dependent protein serine/threonine kinase inhibitor activity,snRNA binding,nucleus,cytoplasm,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,heart development,negative regulation of transcription, DNA-dependent,negative regulation of cyclin-dependent protein serine/threonine kinase activity","."]
["HEXIM2","hexamethylene bis-acetamide inducible 2 [Source:HGNC Symbol;Acc:28591]","ENSG00000168517","ENSP00000302276",2,"HEXIM[1],Herpes_BLRF2[1]","family-466","HEXIM1,HEXIM2","HEXIM1","HEXIM2[33,42]","ncRNA","7SK RNA",21853533,".",".",".",".",".",".","GO:0017069","snRNA binding","GO:0005515,GO:0004861,GO:0017069,GO:0005634,GO:0005737,GO:0000122,GO:0006351,GO:0045892,GO:0045736","protein binding,cyclin-dependent protein serine/threonine kinase inhibitor activity,snRNA binding,nucleus,cytoplasm,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,negative regulation of transcription, DNA-dependent,negative regulation of cyclin-dependent protein serine/threonine kinase activity","."]
["SRRM2","serine/arginine repetitive matrix 2 [Source:HGNC Symbol;Acc:16639]","ENSG00000167978","ENSP00000458230",1,"cwf21[1]","family-467","SRRM2,SRRM3","SRRM2","SRRM3[7,32]","mRNA","mRNA",10668804,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0071013,GO:0000398","RNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0003723,GO:0047485,GO:0070742,GO:0005634,GO:0016607,GO:0015030,GO:0071013,GO:0000398","RNA binding,protein N-terminus binding,C2H2 zinc finger domain binding,nucleus,nuclear speck,Cajal body,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["SRRM3","serine/arginine repetitive matrix 3 [Source:HGNC Symbol;Acc:26729]","ENSG00000262321","ENSP00000458336",2,"cwf21[1],SRRM_C[1]","family-467","SRRM2,SRRM3","SRRM2","SRRM3[7,32]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["PIH1D3","PIH1 domain containing 3 [Source:HGNC Symbol;Acc:28570]","ENSG00000080572","ENSP00000337757",1,"PIH1[1]","family-468","PIH1D3",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".",".",".","."]
["DHX40","DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Source:HGNC Symbol;Acc:18018]","ENSG00000108406","ENSP00000388749",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-469","DHX38,DHX40","DHX38","DHX40[24,37]","mRNA","mRNA","PRP16 yeast homolog",".",".",".",".",".",".",".",".","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0006810","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,transport","."]
["DHX38","DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Source:HGNC Symbol;Acc:17211]","ENSG00000140829","ENSP00000268482",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-469","DHX38,DHX40","DHX38","DHX40[24,37]","mRNA","mRNA","This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. [provided by RefSeq, Jul 2008]","helicase",".",".",1,".",".","GO:0071013,GO:0008380,GO:0000398,GO:0006406,GO:0031124","catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0005524,GO:0003676,GO:0004386,GO:0005515,GO:0008026,GO:0005634,GO:0005654,GO:0071013,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","ATP binding,nucleic acid binding,helicase activity,protein binding,ATP-dependent helicase activity,nucleus,nucleoplasm,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["TRMT61B","tRNA methyltransferase 61 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:26070]","ENSG00000171103","ENSP00000302801",1,"GCD14[1]","family-47","TRMT61B",".",".","tRNA","tRNA",23097428,".",".",".",".",".",".","GO:0016429,GO:0031515,GO:0030488,GO:0070901","tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,tRNA methylation,mitochondrial tRNA methylation","GO:0004719,GO:0016429,GO:0031515,GO:0006464,GO:0030488,GO:0005515,GO:0005739,GO:0051260,GO:0070901","protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,cellular protein modification process,tRNA methylation,protein binding,mitochondrion,protein homooligomerization,mitochondrial tRNA methylation","."]
["CSDC2","cold shock domain containing C2, RNA binding [Source:HGNC Symbol;Acc:30359]","ENSG00000172346","ENSP00000417127",1,"CSD[1]","family-470","CARHSP1,CSDC2","CARHSP1","CSDC2[63,60]","mRNA","mRNA",12767259,".",".",".",".",".",1,"GO:0003723,GO:0006398","RNA binding,histone mRNA 3'-end processing","GO:0003677,GO:0006355,GO:0003723,GO:0003676,GO:0005634,GO:0005737,GO:0006398","DNA binding,regulation of transcription, DNA-dependent,RNA binding,nucleic acid binding,nucleus,cytoplasm,histone mRNA 3'-end processing","."]
["CARHSP1","calcium regulated heat stable protein 1, 24kDa [Source:HGNC Symbol;Acc:17150]","ENSG00000153048","ENSP00000455855",1,"CSD[1]","family-470","CARHSP1,CSDC2","CARHSP1","CSDC2[63,60]","mRNA","mRNA",21078874,".",".",".",".",".",1,"GO:0003730,GO:0000932,GO:0000177,GO:0043186,GO:0043488","mRNA 3'-UTR binding,cytoplasmic mRNA processing body,cytoplasmic exosome (RNase complex),P granule,regulation of mRNA stability","GO:0005737,GO:0003677,GO:0006355,GO:0003676,GO:0019902,GO:0003730,GO:0005829,GO:0000932,GO:0000177,GO:0043186,GO:0035556,GO:0043488","cytoplasm,DNA binding,regulation of transcription, DNA-dependent,nucleic acid binding,phosphatase binding,mRNA 3'-UTR binding,cytosol,cytoplasmic mRNA processing body,cytoplasmic exosome (RNase complex),P granule,intracellular signal transduction,regulation of mRNA stability","."]
["POP4","processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:30081] ","ENSG00000105171","ENSP00000465213",1,"UPF0086[1]","family-471","POP4",".",".","ncRNA","MRP RNA","This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]",".",".",".",".",".",".","GO:0003723,GO:0004540,GO:0000172,GO:0030677,GO:0006364,GO:0008033,GO:0006379,GO:0004526,GO:0005655","RNA binding,ribonuclease activity,ribonuclease MRP complex,ribonuclease P complex,rRNA processing,tRNA processing,mRNA cleavage,ribonuclease P activity,nucleolar ribonuclease P complex","GO:0003723,GO:0004540,GO:0000172,GO:0030677,GO:0006364,GO:0008033,GO:0006379,GO:0005515,GO:0004526,GO:0005655","RNA binding,ribonuclease activity,ribonuclease MRP complex,ribonuclease P complex,rRNA processing,tRNA processing,mRNA cleavage,protein binding,ribonuclease P activity,nucleolar ribonuclease P complex","."]
["LARP6","La ribonucleoprotein domain family, member 6 [Source:HGNC Symbol;Acc:24012]","ENSG00000166173","ENSP00000299213",2,"SUZ-C[1],La[1]","family-472","LARP6",".",".","mRNA","putative mRNA",24469459,".",".",".",".",".",1,"GO:0003723,GO:0030529,GO:0006417,GO:0006396","RNA binding,ribonucleoprotein complex,regulation of translation,RNA processing","GO:0000166,GO:0003723,GO:0005634,GO:0043231,GO:0005794,GO:0030529,GO:0006417,GO:0006396","nucleotide binding,RNA binding,nucleus,intracellular membrane-bounded organelle,Golgi apparatus,ribonucleoprotein complex,regulation of translation,RNA processing","."]
["RNPC3","RNA-binding region (RNP1, RRM) containing 3 [Source:HGNC Symbol;Acc:18666]","ENSG00000185946","ENSP00000391432",2,"RRM_1[2]","family-473","RNPC3",".",".","snRNA","snRNA","Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]",".",".",".",".",".",1,"GO:0003723,GO:0005689,GO:0006397,GO:0008380","RNA binding,U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005689,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,nucleus,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["RPL30","ribosomal protein L30 [Source:HGNC Symbol;Acc:10333]","ENSG00000156482","ENSP00000428085",1,"Ribosomal_L7Ae[1]","family-474","RPL30",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005737,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytoplasm,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RUVBL2","RuvB-like 2 (E. coli) [Source:HGNC Symbol;Acc:10475] [Type: protein coding Ensembl/Havana merge]","ENSG00000183207","ENSP00000473172",1,"TIP49[1]","family-475","RUVBL2",".",".","mRNA","mRNA",20371770,".",".",".",".",".",".","GO:0030529","ribonucleoprotein complex","GO:0000166,GO:0005524,GO:0017111,GO:0003678,GO:0003684,GO:0043141,GO:0030529,GO:0006281,GO:0006260,GO:0016887,GO:0005515,GO:0051082,GO:0004003,GO:0042802,GO:0005634,GO:0005737,GO:0016020,GO:0005622,GO:0016363,GO:0031011,GO:0071339,GO:0035267,GO:0006351,GO:0006457,GO:0006355,GO:0006200,GO:0006310,GO:0040008,GO:0034644,GO:0032508,GO:0043967,GO:0043968","nucleotide binding,ATP binding,nucleoside-triphosphatase activity,DNA helicase activity,damaged DNA binding,ATP-dependent 5'-3' DNA helicase activity,ribonucleoprotein complex,DNA repair,DNA replication,ATPase activity,protein binding,unfolded protein binding,ATP-dependent DNA helicase activity,identical protein binding,nucleus,cytoplasm,membrane,intracellular,nuclear matrix,Ino80 complex,MLL1 complex,NuA4 histone acetyltransferase complex,transcription, DNA-templated,protein folding,regulation of transcription, DNA-dependent,ATP catabolic process,DNA recombination,regulation of growth,cellular response to UV,DNA duplex unwinding,histone H4 acetylation,histone H2A acetylation","."]
["DRG1","developmentally regulated GTP binding protein 1 [Source:HGNC Symbol;Acc:3029]","ENSG00000185721","ENSP00000329715",2,"MMR_HSR1[1],TGS[1]","family-476","DRG1",".",".","mRNA","putative mRNA","RBG1, 19819225",".",".",".",".",".",".",".",".","GO:0005515,GO:0005525,GO:0008134,GO:0042802,GO:0015093,GO:0016021,GO:0005634,GO:0005737,GO:0045111,GO:0005844,GO:0006351,GO:0007275,GO:0015684","protein binding,GTP binding,transcription factor binding,identical protein binding,ferrous iron transmembrane transporter activity,integral to membrane,nucleus,cytoplasm,intermediate filament cytoskeleton,polysome,transcription, DNA-templated,multicellular organismal development,ferrous iron transport","."]
["TRIM25","tripartite motif containing 25 [Source:HGNC Symbol;Acc:12932]","ENSG00000121060","ENSP00000323889",4,"SPRY[1],PRY[1],zf-C3HC4_4[1],zf-B_box[1]","family-477","TRIM25,TRIM16,TRIM16L,TRIM47,TRIM65","TRIM25","TRIM16[20,23],TRIM16L[12,21],TRIM47[24,24],TRIM65[20,25]","mRNA","mRNA",23912277,".","RNArelated",".",1,1,".",".",".","GO:0003700,GO:0005515,GO:0008270,GO:0046872,GO:0004842,GO:0005634,GO:0005737,GO:0005829,GO:0030054,GO:0045087,GO:0006355,GO:0032480,GO:0051607,GO:0019048,GO:0033280,GO:0043627","sequence-specific DNA binding transcription factor activity,protein binding,zinc ion binding,metal ion binding,ubiquitin-protein ligase activity,nucleus,cytoplasm,cytosol,cell junction,innate immune response,regulation of transcription, DNA-dependent,negative regulation of type I interferon production,defense response to virus,modulation by virus of host morphology or physiology,response to vitamin D,response to estrogen","."]
["RQCD1","RCD1 required for cell differentiation1 homolog (S. pombe) [Source:HGNC Symbol;Acc:10445]","ENSG00000144580","ENSP00000273064",1,"Rcd1[1]","family-478","RQCD1",".",".","mRNA","mRNA","UniProtKB/Swiss-Prot: RCD1_HUMAN, Q92600",".",".",".",".",".",".","GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","GO:0005488,GO:0005515,GO:0005634,GO:0005829,GO:0000932,GO:0030014,GO:0006351,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047,GO:0033147,GO:0019221,GO:0007548,GO:2000327","binding,protein binding,nucleus,cytosol,cytoplasmic mRNA processing body,CCR4-NOT complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA,negative regulation of intracellular estrogen receptor signaling pathway,cytokine-mediated signaling pathway,sex differentiation,positive regulation of ligand-dependent nuclear receptor transcription coactivator activity","."]
["MRPS18C","mitochondrial ribosomal protein S18C [Source:HGNC Symbol;Acc:16633]","ENSG00000163319","ENSP00000295491",1,"Ribosomal_S18[1]","family-479","MRPS18C",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",1,".","GO:0003735,GO:0005840,GO:0006412,GO:0005763","structural constituent of ribosome,ribosome,translation,mitochondrial small ribosomal subunit","GO:0003735,GO:0005840,GO:0006412,GO:0005622,GO:0005739,GO:0005763","structural constituent of ribosome,ribosome,translation,intracellular,mitochondrion,mitochondrial small ribosomal subunit","."]
["MRPL45","mitochondrial ribosomal protein L45 [Source:HGNC Symbol;Acc:16651]","ENSG00000174100","ENSP00000308901",1,"Tim44[1]","family-48","MRPL45",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005840,GO:0006412","structural constituent of ribosome,mitochondrion,ribosome,translation","."]
["RPLP2","ribosomal protein, large, P2 [Source:HGNC Symbol;Acc:10377]","ENSG00000177600","ENSP00000322419",1,"Ribosomal_60s[1]","family-480","RPLP2",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006414,GO:0003723,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translational elongation,RNA binding,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006414,GO:0003723,GO:0005829,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translational elongation,RNA binding,cytosol,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["SRP19","signal recognition particle 19kDa [Source:HGNC Symbol;Acc:11300]","ENSG00000153037","ENSP00000424870",1,"SRP19[1]","family-481","SRP19",".",".","ncRNA","SRP RNA","The signal recognition particle (SRP) binds to the signal peptide of proteins as they are being translated. The binding of the SRP halts translation and the complex is then transported to the endoplasmic reticulum's cytoplasmic surface. The SRP then aids translocation of the protein through the ER membrane. The SRP is a ribonucleoprotein that is composed of a small RNA and several proteins. One of these proteins is the SRP19 protein [1] (Sec65 in yeast [2,3]).",".","RNAbinding",".",1,".",".","GO:0008312,GO:0006412","7S RNA binding,translation","GO:0008312,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005730,GO:0005786,GO:0006412,GO:0042493,GO:0010467,GO:0006613,GO:0044267,GO:0006614,GO:0048500","7S RNA binding,nucleus,cytoplasm,mitochondrion,cytosol,nucleolus,signal recognition particle, endoplasmic reticulum targeting,translation,response to drug,gene expression,cotranslational protein targeting to membrane,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,signal recognition particle","."]
["RPS24","ribosomal protein S24 [Source:HGNC Symbol;Acc:10411]","ENSG00000138326","ENSP00000415549",1,"Ribosomal_S24e[1]","family-482","RPS24",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0031369,GO:0022627,GO:0015935,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274,GO:0000462","structural constituent of ribosome,ribosome,translation,translation initiation factor binding,cytosolic small ribosomal subunit,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0000166,GO:0003735,GO:0005634,GO:0005737,GO:0005622,GO:0005840,GO:0006412,GO:0031369,GO:0005829,GO:0005730,GO:0022627,GO:0015935,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0034101,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274,GO:0000462","nucleotide binding,structural constituent of ribosome,nucleus,cytoplasm,intracellular,ribosome,translation,translation initiation factor binding,cytosol,nucleolus,cytosolic small ribosomal subunit,small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,erythrocyte homeostasis,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"," DIAMOND-BLACKFAN ANEMIA 3; DBA3"]
["AKAP17A","A kinase (PRKA) anchor protein 17A [Source:HGNC Symbol;Acc:18783]","ENSG00000197976","ENSP00000324827",".",".","family-483","AKAP17A",".",".","mRNA","putative mRNA",19840947,"RNAbinding",".",".",1,".",".","GO:0003723,GO:0005681,GO:0006397,GO:0008380,GO:0043484","RNA binding,spliceosomal complex,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0051018,GO:0005634,GO:0005681,GO:0016607,GO:0006355,GO:0007165,GO:0006397,GO:0008380,GO:0043484,GO:0042113","nucleotide binding,RNA binding,protein binding,protein kinase A binding,nucleus,spliceosomal complex,nuclear speck,regulation of transcription, DNA-dependent,signal transduction,mRNA processing,RNA splicing,regulation of RNA splicing,B cell activation","."]
["NXT2","nuclear transport factor 2-like export factor 2 [Source:HGNC Symbol;Acc:18151]","ENSG00000101888","ENSP00000361178",1,"NTF2[1]","family-484","NXT1,NXT2","NXT1","NXT2[74,53]","mRNA","mRNA","The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011]",".",".",".",".",".",".","GO:0051028","mRNA transport","GO:0005634,GO:0005737,GO:0005622,GO:0015031,GO:0006810,GO:0051028,GO:0005515","nucleus,cytoplasm,intracellular,protein transport,transport,mRNA transport,protein binding","."]
["NXT1","NTF2-like export factor 1 [Source:HGNC Symbol;Acc:15913]","ENSG00000132661","ENSP00000254998",1,"NTF2[1]","family-484","NXT1,NXT2","NXT1","NXT2[74,53]","mRNA","mRNA/tRNA","The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0006405","RNA export from nucleus","GO:0005515,GO:0008536,GO:0005737,GO:0005622,GO:0005643,GO:0016607,GO:0006611,GO:0006810,GO:0006405","protein binding,Ran GTPase binding,cytoplasm,intracellular,nuclear pore,nuclear speck,protein export from nucleus,transport,RNA export from nucleus","."]
["MRPL9","mitochondrial ribosomal protein L9 [Source:HGNC Symbol;Acc:14277]","ENSG00000143436","ENSP00000357823",1,"Ribosomal_L9_N[1]","family-485","MRPL9",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,ribosome,translation,mitochondrial ribosome","GO:0003735,GO:0005739,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,mitochondrion,ribosome,translation,mitochondrial ribosome","."]
["RPL27","ribosomal protein L27 [Source:HGNC Symbol;Acc:10328]","ENSG00000131469","ENSP00000253788",2,"KOW[1],Ribosomal_L27e[1]","family-486","RPL27",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0030529,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,ribonucleoprotein complex,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005829,GO:0030529,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,cytosol,ribonucleoprotein complex,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL24","ribosomal protein L24 [Source:HGNC Symbol;Acc:10325]","ENSG00000114391","ENSP00000377640",1,"Ribosomal_L24e[1]","family-487","RPL24",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0005840,GO:0003735,GO:0003723,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","ribosome,structural constituent of ribosome,RNA binding,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005840,GO:0003735,GO:0003723,GO:0022625,GO:0005829,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","ribosome,structural constituent of ribosome,RNA binding,cytosolic large ribosomal subunit,cytosol,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["CNOT10","CCR4-NOT transcription complex, subunit 10 [Source:HGNC Symbol;Acc:23817]","ENSG00000182973","ENSP00000399862",3,"TPR_1[2],BLOC1_2[1]","family-488","CNOT10",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","GO:0005515,GO:0005634,GO:0005829,GO:0030014,GO:0006351,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","protein binding,nucleus,cytosol,CCR4-NOT complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","."]
["ABT1","activator of basal transcription 1 [Source:HGNC Symbol;Acc:17369]","ENSG00000146109","ENSP00000274849",1,"RRM_6[1]","family-489","ABT1",".",".","mRNA","putative mRNA","by domain, 22658674, 22681889","RNAbinding","RNAbinding",1,1,1,".","GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0003677,GO:0003713,GO:0005634,GO:0005667,GO:0005730,GO:0006366,GO:0006357,GO:0021522","nucleotide binding,RNA binding,protein binding,DNA binding,transcription coactivator activity,nucleus,transcription factor complex,nucleolus,transcription from RNA polymerase II promoter,regulation of transcription from RNA polymerase II promoter,spinal cord motor neuron differentiation","."]
["DDX25","DEAD (Asp-Glu-Ala-Asp) box helicase 25 [Source:HGNC Symbol;Acc:18698]","ENSG00000109832","ENSP00000463333",2,"Helicase_C[1],DEAD[1]","family-49","DDX19A,DDX19B,DDX25","DDX19A","DDX19B[96,95],DDX25[64,63]","mRNA","mRNA",19875492,".",".",".",".",".",".","GO:0004004,GO:0003723,GO:0006406,GO:0006417","ATP-dependent RNA helicase activity,RNA binding,mRNA export from nucleus,regulation of translation","GO:0005524,GO:0003676,GO:0004386,GO:0008026,GO:0004004,GO:0003723,GO:0005737,GO:0005634,GO:0033391,GO:0006406,GO:0007286,GO:0006417,GO:0007275","ATP binding,nucleic acid binding,helicase activity,ATP-dependent helicase activity,ATP-dependent RNA helicase activity,RNA binding,cytoplasm,nucleus,chromatoid body,mRNA export from nucleus,spermatid development,regulation of translation,multicellular organismal development","."]
["DDX19A","DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A [Source:HGNC Symbol;Acc:25628]","ENSG00000168872","ENSP00000399208",2,"Helicase_C[1],DEAD[1]","family-49","DDX19A,DDX19B,DDX25","DDX19A","DDX19B[96,95],DDX25[64,63]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0051028","RNA binding,mRNA transport","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0010043,GO:0003723,GO:0005737,GO:0031965,GO:0005643,GO:0043065,GO:0015031,GO:0051028","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,response to zinc ion,RNA binding,cytoplasm,nuclear membrane,nuclear pore,positive regulation of apoptotic process,protein transport,mRNA transport","."]
["DDX19B","Uncharacterized protein  [Source:UniProtKB/TrEMBL;Acc:H3BN59]","ENSG00000260537","ENSP00000454699",1,"DEAD[1]","family-49","DDX19A,DDX19B,DDX25","DDX19A","DDX19B[96,95],DDX25[64,63]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0006406","RNA binding,mRNA export from nucleus","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005737,GO:0031965,GO:0005643,GO:0005635,GO:0015031,GO:0006406","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,cytoplasm,nuclear membrane,nuclear pore,nuclear envelope,protein transport,mRNA export from nucleus","."]
["MRPS30","mitochondrial ribosomal protein S30 [Source:HGNC Symbol;Acc:8769]","ENSG00000112996","ENSP00000424328",1,"PDCD9[1]","family-490","MRPS30",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,1,".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005840,GO:0006915,GO:0006412","structural constituent of ribosome,mitochondrion,ribosome,apoptotic process,translation","."]
["SMG1","smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) [Source:HGNC Symbol;Acc:30045]","ENSG00000157106","ENSP00000402515",2,"PI3_PI4_kinase[1],FATC[1]","family-491","SMG1",".",".","mRNA","mRNA","This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]","candidate mRNA binder",".",".",1,".",".","GO:0016070,GO:0016071,GO:0006406,GO:0000184","RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005488,GO:0005515,GO:0005524,GO:0016301,GO:0016773,GO:0016772,GO:0046872,GO:0004674,GO:0004672,GO:0005634,GO:0005737,GO:0005829,GO:0006281,GO:0046854,GO:0010467,GO:0016070,GO:0016071,GO:0006950,GO:0018105,GO:0046777,GO:0006406,GO:0000184","binding,protein binding,ATP binding,kinase activity,phosphotransferase activity, alcohol group as acceptor,transferase activity, transferring phosphorus-containing groups,metal ion binding,protein serine/threonine kinase activity,protein kinase activity,nucleus,cytoplasm,cytosol,DNA repair,phosphatidylinositol phosphorylation,gene expression,RNA metabolic process,mRNA metabolic process,response to stress,peptidyl-serine phosphorylation,protein autophosphorylation,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["EXOSC5","exosome component 5 [Source:HGNC Symbol;Acc:24662]","ENSG00000077348","ENSP00000471002",2,"RNase_PH[1],RNase_PH_C[1]","family-492","EXOSC5",".",".","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000175,GO:0000178,GO:0006401,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","RNA binding,3'-5'-exoribonuclease activity,exosome (RNase complex),RNA catabolic process,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0000175,GO:0005737,GO:0005829,GO:0005730,GO:0000178,GO:0035327,GO:0006401,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0051607,GO:0043928,GO:0045006","RNA binding,protein binding,3'-5'-exoribonuclease activity,cytoplasm,cytosol,nucleolus,exosome (RNase complex),transcriptionally active chromatin,RNA catabolic process,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,defense response to virus,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,DNA deamination","."]
["AIMP2","aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 [Source:HGNC Symbol;Acc:20609]","ENSG00000106305","ENSP00000223029",1,"GST_C_3[1]","family-493","AIMP2",".",".","tRNA","putative tRNA","established RBP ",".",".",".",".",".",".","GO:0006418","tRNA aminoacylation for protein translation","GO:0005634,GO:0008285,GO:0031398,GO:0060510,GO:0005515,GO:0005829,GO:0006915,GO:0010467,GO:0006418","nucleus,negative regulation of cell proliferation,positive regulation of protein ubiquitination,Type II pneumocyte differentiation,protein binding,cytosol,apoptotic process,gene expression,tRNA aminoacylation for protein translation","."]
["BZW2","basic leucine zipper and W2 domains 2 [Source:HGNC Symbol;Acc:18808]","ENSG00000136261","ENSP00000385577",1,"W2[1]","family-494","BZW1,BZW2","BZW1","BZW2[67,72]","mRNA","putative mRNA",21745818,".",".",".",".",1,".",".",".","GO:0005488,GO:0005515,GO:0030154,GO:0007399","binding,protein binding,cell differentiation,nervous system development","."]
["BZW1","basic leucine zipper and W2 domains 1 [Source:HGNC Symbol;Acc:18380]","ENSG00000082153","ENSP00000395673",1,"W2[1]","family-494","BZW1,BZW2","BZW1","BZW2[67,72]","mRNA","putative mRNA","by homology","candidate mRNA binder","RNArelated",1,1,1,".",".",".","GO:0005515,GO:0005488,GO:0005737,GO:0006351,GO:0006355","protein binding,binding,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["PARS2","prolyl-tRNA synthetase 2, mitochondrial (putative) [Source:HGNC Symbol;Acc:30563]","ENSG00000162396","ENSP00000360327",2,"tRNA-synt_2b[1],HGTP_anticodon[1]","family-495","PARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004827,GO:0006418,GO:0006433","aminoacyl-tRNA ligase activity,proline-tRNA ligase activity,tRNA aminoacylation for protein translation,prolyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004827,GO:0005739,GO:0005759,GO:0010467,GO:0006418,GO:0006433","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,proline-tRNA ligase activity,mitochondrion,mitochondrial matrix,gene expression,tRNA aminoacylation for protein translation,prolyl-tRNA aminoacylation","."]
["INTS12","integrator complex subunit 12 [Source:HGNC Symbol;Acc:25067] [Type: protein coding Ensembl/Havana merge]","ENSG00000138785","ENSP00000415433",1,"PHD[1]","family-496","INTS12",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0008270,GO:0032039,GO:0016180","protein binding,zinc ion binding,integrator complex,snRNA processing","."]
["EIF3H","eukaryotic translation initiation factor 3, subunit H [Source:HGNC Symbol;Acc:3273]","ENSG00000147677","ENSP00000429931",2,"XkdN[1],JAB[1]","family-497","EIF3H",".",".","mRNA","putative mRNA","established RBP ",".","novel",".",1,".",".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0006412,GO:0001731,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0005515,GO:0003743,GO:0005852,GO:0005737,GO:0005829,GO:0016282,GO:0033290,GO:0006412,GO:0010467,GO:0001731,GO:0006446,GO:0044267,GO:0006413","protein binding,translation initiation factor activity,eukaryotic translation initiation factor 3 complex,cytoplasm,cytosol,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,gene expression,formation of translation preinitiation complex,regulation of translational initiation,cellular protein metabolic process,translational initiation","."]
["SKIV2L","superkiller viralicidic activity 2-like (S. cerevisiae) [Source:HGNC Symbol;Acc:10898]","ENSG00000223493","ENSP00000412310",5,"Helicase_C[1],rRNA_proc-arch[2],DSHCT[1],DEAD[1]","family-498","SKIV2L",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004004,GO:0055087","RNA binding,ATP-dependent RNA helicase activity,Ski complex","GO:0003723,GO:0005524,GO:0003676,GO:0016817,GO:0008026,GO:0004386,GO:0016818,GO:0004004,GO:0005634,GO:0055087","RNA binding,ATP binding,nucleic acid binding,hydrolase activity, acting on acid anhydrides,ATP-dependent helicase activity,helicase activity,hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides,ATP-dependent RNA helicase activity,nucleus,Ski complex"," TRICHOHEPATOENTERIC SYNDROME 2; THES2"]
["RC3H2","ring finger and CCCH-type domains 2 [Source:HGNC Symbol;Acc:21461]","ENSG00000056586","ENSP00000411767",2,"zf-RING_5[1],zf-CCCH[1]","family-499","RC3H1,RC3H2","RC3H1","RC3H2[53,50]","mRNA","putative mRNA","by homology, roquin 2","RNAbinding","novel",1,1,".",1,"GO:0003723,GO:0000932","RNA binding,cytoplasmic mRNA processing body","GO:0003723,GO:0005515,GO:0008270,GO:0046872,GO:0003677,GO:0016020,GO:0000932,GO:0009986","RNA binding,protein binding,zinc ion binding,metal ion binding,DNA binding,membrane,cytoplasmic mRNA processing body,cell surface","."]
["RC3H1","ring finger and CCCH-type domains 1 [Source:HGNC Symbol;Acc:29434]","ENSG00000135870","ENSP00000356667",2,"zf-CCCH[1],zf-RING_UBOX[1]","family-499","RC3H1,RC3H2","RC3H1","RC3H2[53,50]","mRNA","mRNA","RC3H1, or roquin, encodes a highly conserved member of the RING type ubiquitin ligase protein family (Vinuesa et al., 2005 [PubMed 15917799]). The roquin protein is distinguished by the presence of a CCCH zinc finger found in RNA-binding proteins, and localization to cytosolic RNA granules implicated in regulating mRNA translation and stability.[supplied by OMIM, Mar 2008]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003730,GO:0000932,GO:0010494,GO:0043488,GO:0033962,GO:0000956","mRNA 3'-UTR binding,cytoplasmic mRNA processing body,cytoplasmic stress granule,regulation of mRNA stability,cytoplasmic mRNA processing body assembly,nuclear-transcribed mRNA catabolic process","GO:0005515,GO:0008270,GO:0046872,GO:0004842,GO:0003730,GO:0000932,GO:0010494,GO:0016567,GO:0046007,GO:0030889,GO:0043488,GO:0002634,GO:0033962,GO:0050856,GO:0000956,GO:0002635,GO:0010608,GO:0045623,GO:0005737","protein binding,zinc ion binding,metal ion binding,ubiquitin-protein ligase activity,mRNA 3'-UTR binding,cytoplasmic mRNA processing body,cytoplasmic stress granule,protein ubiquitination,negative regulation of activated T cell proliferation,negative regulation of B cell proliferation,regulation of mRNA stability,regulation of germinal center formation,cytoplasmic mRNA processing body assembly,regulation of T cell receptor signaling pathway,nuclear-transcribed mRNA catabolic process,negative regulation of germinal center formation,posttranscriptional regulation of gene expression,negative regulation of T-helper cell differentiation,cytoplasm","."]
["ZFP36","ZFP36 ring finger protein [Source:HGNC Symbol;Acc:12862]","ENSG00000128016","ENSP00000248673",2,"zf-CCCH[2]","family-5","ZFP36,ZFP36L2,ZFP36L1","ZFP36","ZFP36L2[32,21],ZFP36L1[35,34]","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,".",1,"GO:0003727,GO:0003729,GO:0017091,GO:0010494,GO:0016070,GO:0016071,GO:0000288,GO:0060213,GO:1900153,GO:0006402,GO:0070935,GO:0035925,GO:0000289,GO:0043488,GO:0050779","single-stranded RNA binding,mRNA binding,AU-rich element binding,cytoplasmic stress granule,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA catabolic process,3'-UTR-mediated mRNA stabilization,mRNA 3'-UTR AU-rich region binding,nuclear-transcribed mRNA poly(A) tail shortening,regulation of mRNA stability,RNA destabilization","GO:0005515,GO:0046872,GO:0003677,GO:0003727,GO:0019901,GO:0003729,GO:0071889,GO:0017091,GO:0019957,GO:0005634,GO:0005737,GO:0005829,GO:0010494,GO:0000122,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0060213,GO:1900153,GO:0042594,GO:0006402,GO:0035278,GO:0032680,GO:0070935,GO:0035925,GO:0006357,GO:0000289,GO:0050728,GO:0043488,GO:0045638,GO:0050779","protein binding,metal ion binding,DNA binding,single-stranded RNA binding,protein kinase binding,mRNA binding,14-3-3 protein binding,AU-rich element binding,C-C chemokine binding,nucleus,cytoplasm,cytosol,cytoplasmic stress granule,negative regulation of transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,response to starvation,mRNA catabolic process,negative regulation of translation involved in gene silencing by miRNA,regulation of tumor necrosis factor production,3'-UTR-mediated mRNA stabilization,mRNA 3'-UTR AU-rich region binding,regulation of transcription from RNA polymerase II promoter,nuclear-transcribed mRNA poly(A) tail shortening,negative regulation of inflammatory response,regulation of mRNA stability,negative regulation of myeloid cell differentiation,RNA destabilization","."]
["ZFP36L1","ZFP36 ring finger protein-like 1 [Source:HGNC Symbol;Acc:1107]","ENSG00000185650","ENSP00000450784",3,"Tis11B_N[1],zf-CCCH[2]","family-5","ZFP36,ZFP36L2,ZFP36L1","ZFP36","ZFP36L2[32,21],ZFP36L1[35,34]","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,".",1,"GO:0000288,GO:0006417,GO:0003729,GO:0016070,GO:0016071,GO:0043488","nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of translation,mRNA binding,RNA metabolic process,mRNA metabolic process,regulation of mRNA stability","GO:0046872,GO:0005634,GO:0005737,GO:0000288,GO:0006417,GO:0033077,GO:0001570,GO:0003700,GO:0005515,GO:0003677,GO:0003729,GO:0005829,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0043488","metal ion binding,nucleus,cytoplasm,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of translation,T cell differentiation in thymus,vasculogenesis,sequence-specific DNA binding transcription factor activity,protein binding,DNA binding,mRNA binding,cytosol,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,regulation of mRNA stability","."]
["ZFP36L2","ZFP36 ring finger protein-like 2 [Source:HGNC Symbol;Acc:1108]","ENSG00000152518","ENSP00000282388",3,"Tis11B_N[1],zf-CCCH[2]","family-5","ZFP36,ZFP36L2,ZFP36L1","ZFP36","ZFP36L2[32,21],ZFP36L1[35,34]","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,1,1,"GO:0035925,GO:0017091,GO:1900153,GO:0006402,GO:0000288,GO:0043488","mRNA 3'-UTR AU-rich region binding,AU-rich element binding,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA catabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of mRNA stability","GO:0035925,GO:0003700,GO:0046872,GO:0003677,GO:0017091,GO:0005737,GO:0005634,GO:0035019,GO:0033077,GO:0030097,GO:0060216,GO:0048103,GO:1900153,GO:0006402,GO:2000737,GO:0008283,GO:0006355,GO:0000288,GO:0043488","mRNA 3'-UTR AU-rich region binding,sequence-specific DNA binding transcription factor activity,metal ion binding,DNA binding,AU-rich element binding,cytoplasm,nucleus,somatic stem cell maintenance,T cell differentiation in thymus,hemopoiesis,definitive hemopoiesis,somatic stem cell division,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA catabolic process,negative regulation of stem cell differentiation,cell proliferation,regulation of transcription, DNA-dependent,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,regulation of mRNA stability","."]
["ANKHD1","ankyrin repeat and KH domain containing 1 [Source:HGNC Symbol;Acc:24714]","ENSG00000131503","ENSP00000354085",12,"Ank_2[6],Ank[1],KH_1[1],Ank_4[4]","family-50","ANKHD1,ANKRD17","ANKHD1","ANKRD17[60,60]","unknown","unknown","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0005634,GO:0005737","RNA binding,protein binding,nucleus,cytoplasm","."]
["ANKRD17","ankyrin repeat domain 17 [Source:HGNC Symbol;Acc:23575]","ENSG00000132466","ENSP00000351416",13,"Ank_2[6],Ank[3],KH_1[1],Ank_4[3]","family-50","ANKHD1,ANKRD17","ANKHD1","ANKRD17[60,60]","unknown","unknown","established RBP ",".","RNAbinding",".",1,1,1,"GO:0003723","RNA binding","GO:0005515,GO:0003723,GO:0005634,GO:0005737,GO:0001955,GO:0019048,GO:0051151","protein binding,RNA binding,nucleus,cytoplasm,blood vessel maturation,modulation by virus of host morphology or physiology,negative regulation of smooth muscle cell differentiation","."]
["HELZ2","helicase with zinc finger 2, transcriptional coactivator [Source:HGNC Symbol;Acc:30021]","ENSG00000130589","ENSP00000393257",5,"AAA_11[2],RNB[1],AAA_12[2]","family-500","HELZ2,UPF1","HELZ2","UPF1[9,22]","mRNA","putative mRNA",23525231,"helicase","RNAbinding",1,1,".",".",".",".","GO:0005515,GO:0005524,GO:0046872,GO:0003677,GO:0004386,GO:0003713,GO:0030374,GO:0005654,GO:0006351,GO:0045944,GO:0044255,GO:0044281","protein binding,ATP binding,metal ion binding,DNA binding,helicase activity,transcription coactivator activity,ligand-dependent nuclear receptor transcription coactivator activity,nucleoplasm,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,cellular lipid metabolic process,small molecule metabolic process","."]
["UPF1","UPF1 regulator of nonsense transcripts homolog (yeast) [Source:HGNC Symbol;Acc:9962]","ENSG00000005007","ENSP00000262803",3,"AAA_11[1],AAA_12[1],UPF1_Zn_bind[1]","family-500","HELZ2,UPF1","HELZ2","UPF1[9,22]","mRNA","mRNA","This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]","helicase","experimentally validated",1,1,1,1,"GO:0003723,GO:0004004,GO:0000932,GO:0044530,GO:0016070,GO:0016071,GO:0006406,GO:0071044,GO:0000184,GO:0006449","RNA binding,ATP-dependent RNA helicase activity,cytoplasmic mRNA processing body,supraspliceosomal complex,RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of translational termination","GO:0003723,GO:0005515,GO:0008270,GO:0005524,GO:0003677,GO:0016787,GO:0003682,GO:0004386,GO:0004004,GO:0005634,GO:0005737,GO:0005829,GO:0000932,GO:0000785,GO:0035145,GO:0044530,GO:0006281,GO:0010467,GO:0016070,GO:0016071,GO:0006260,GO:0006406,GO:0009048,GO:0071044,GO:0000184,GO:0006449","RNA binding,protein binding,zinc ion binding,ATP binding,DNA binding,hydrolase activity,chromatin binding,helicase activity,ATP-dependent RNA helicase activity,nucleus,cytoplasm,cytosol,cytoplasmic mRNA processing body,chromatin,exon-exon junction complex,supraspliceosomal complex,DNA repair,gene expression,RNA metabolic process,mRNA metabolic process,DNA replication,mRNA export from nucleus,dosage compensation by inactivation of X chromosome,histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of translational termination","."]
["DROSHA","drosha, ribonuclease type III [Source:HGNC Symbol;Acc:17904]","ENSG00000113360","ENSP00000409335",3,"Ribonucleas_3_3[1],dsrm[1],Ribonuclease_3[1]","family-501","DROSHA",".",".","ncRNA","miRNA","established RBP ","nuclease","RNAbinding",1,1,".",".","GO:0003723,GO:0004525,GO:0042254,GO:0006396,GO:0010586,GO:0016075,GO:0031054,GO:0004521","RNA binding,ribonuclease III activity,ribosome biogenesis,RNA processing,miRNA metabolic process,rRNA catabolic process,pre-miRNA processing,endoribonuclease activity","GO:0003723,GO:0005515,GO:0046872,GO:0004525,GO:0005730,GO:0005654,GO:0042254,GO:0010467,GO:0006396,GO:0010586,GO:0016075,GO:0031054,GO:0004521,GO:0010468","RNA binding,protein binding,metal ion binding,ribonuclease III activity,nucleolus,nucleoplasm,ribosome biogenesis,gene expression,RNA processing,miRNA metabolic process,rRNA catabolic process,pre-miRNA processing,endoribonuclease activity,regulation of gene expression","."]
["MRPL37","mitochondrial ribosomal protein L37 [Source:HGNC Symbol;Acc:14034]","ENSG00000116221","ENSP00000354086",1,"PDCD9[1]","family-502","MRPL37",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,ribosome,translation,mitochondrial ribosome","GO:0003735,GO:0005739,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,mitochondrion,ribosome,translation,mitochondrial ribosome","."]
["PUS10","pseudouridylate synthase 10 [Source:HGNC Symbol;Acc:26505]","ENSG00000162927","ENSP00000326003",1,"TPD[1]","family-503","PUS10",".",".","tRNA","tRNA/rRNA",17900615,".",".",".",".",".",".","GO:0003723,GO:0008033,GO:0009451","RNA binding,tRNA processing,RNA modification","GO:0003723,GO:0009982,GO:0008033,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,tRNA processing,pseudouridine synthesis,RNA modification","."]
["NUDT16","nudix (nucleoside diphosphate linked moiety X)-type motif 16 [Source:HGNC Symbol;Acc:26442]","ENSG00000198585","ENSP00000429274",1,"NUDIX[1]","family-504","NUDT16,NUDT16L1","NUDT16","NUDT16L1[38,41]","snoRNA","snoRNA/mRNA",21337011,".",".",".",".",".",".","GO:0003729,GO:0030515,GO:0050072,GO:0006402,GO:2000233,GO:0016077","mRNA binding,snoRNA binding,m7G(5')pppN diphosphatase activity,mRNA catabolic process,negative regulation of rRNA processing,snoRNA catabolic process","GO:0042803,GO:0005525,GO:0000287,GO:0016787,GO:0003729,GO:0030145,GO:0030515,GO:0008235,GO:0050897,GO:0098519,GO:0050072,GO:0035870,GO:0090450,GO:0097383,GO:1901640,GO:1901641,GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0044281,GO:0008284,GO:0006402,GO:0006382,GO:0046709,GO:0055086,GO:0090068,GO:0034656,GO:2000781,GO:2000233,GO:0016077,GO:0035863,GO:1901639","protein homodimerization activity,GTP binding,magnesium ion binding,hydrolase activity,mRNA binding,manganese ion binding,snoRNA binding,metalloexopeptidase activity,cobalt ion binding,nucleotide phosphatase activity, acting on free nucleotides,m7G(5')pppN diphosphatase activity,dITP diphosphatase activity,inosine-diphosphatase activity,dIDP diphosphatase activity,XTP binding,ITP binding,nucleus,cytoplasm,nucleolus,nucleoplasm,small molecule metabolic process,positive regulation of cell proliferation,mRNA catabolic process,adenosine to inosine editing,IDP catabolic process,nucleobase-containing small molecule metabolic process,positive regulation of cell cycle process,nucleobase-containing small molecule catabolic process,positive regulation of double-strand break repair,negative regulation of rRNA processing,snoRNA catabolic process,dITP catabolic process,XDP catabolic process","."]
["NUDT16L1","nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 [Source:HGNC Symbol;Acc:28154]","ENSG00000168101","ENSP00000306670",".",".","family-504","NUDT16,NUDT16L1","NUDT16","NUDT16L1[38,41]","snoRNA","putative snoRNA",21337011,"candidate mRNA binder",".",".",1,".",".","GO:0030515","snoRNA binding","GO:0016787,GO:0030515,GO:0005737","hydrolase activity,snoRNA binding,cytoplasm","."]
["TRMT11","tRNA methyltransferase 11 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:21080]","ENSG00000066651","ENSP00000333934",1,"UPF0020[1]","family-505","TRMT11",".",".","tRNA","putative tRNA","Catalytic subunit of adoMet-dependent tRNA methyltransferase complex; required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain; another complex member is Trm112p",".",".",".",".",".",".","GO:0000049,GO:0008033","tRNA binding,tRNA processing","GO:0000049,GO:0008168,GO:0008033,GO:0003677,GO:0008170,GO:0006306","tRNA binding,methyltransferase activity,tRNA processing,DNA binding,N-methyltransferase activity,DNA methylation","."]
["PET112","PET112 homolog (yeast) [Source:HGNC Symbol;Acc:8849]","ENSG00000059691","ENSP00000426859",2,"GatB_Yqey[1],GatB_N[1]","family-506","PET112",".",".","tRNA","tRNA",19805282,".",".",".",".",".",".","GO:0008135,GO:0050567,GO:0030956,GO:0006412,GO:0032543","translation factor activity, nucleic acid binding,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,glutamyl-tRNA(Gln) amidotransferase complex,translation,mitochondrial translation","GO:0016874,GO:0016884,GO:0016740,GO:0005739,GO:0005524,GO:0008135,GO:0050567,GO:0030956,GO:0006412,GO:0032543,GO:0070681","ligase activity,carbon-nitrogen ligase activity, with glutamine as amido-N-donor,transferase activity,mitochondrion,ATP binding,translation factor activity, nucleic acid binding,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,glutamyl-tRNA(Gln) amidotransferase complex,translation,mitochondrial translation,glutaminyl-tRNAGln biosynthesis via transamidation","."]
["NUFIP1","nuclear fragile X mental retardation protein interacting protein 1 [Source:HGNC Symbol;Acc:8057]","ENSG00000083635","ENSP00000368459",2,"zf-C2H2_jaz[1],NUFIP1[1]","family-507","NUFIP1",".",".","snoRNA","snoRNA/mRNA",17636026,".",".",".",".",".",1,"GO:0003723,GO:0030515,GO:0022626,GO:0070761,GO:0006396,GO:0000492","RNA binding,snoRNA binding,cytosolic ribosome,pre-snoRNP complex,RNA processing,box C/D snoRNP assembly","GO:0005515,GO:0003723,GO:0046872,GO:0003677,GO:0042802,GO:0030674,GO:0030515,GO:0005634,GO:0005730,GO:0048786,GO:0008023,GO:0016363,GO:0022626,GO:0070761,GO:0005726,GO:0045944,GO:0006396,GO:0000492","protein binding,RNA binding,metal ion binding,DNA binding,identical protein binding,protein binding, bridging,snoRNA binding,nucleus,nucleolus,presynaptic active zone,transcription elongation factor complex,nuclear matrix,cytosolic ribosome,pre-snoRNP complex,perichromatin fibrils,positive regulation of transcription from RNA polymerase II promoter,RNA processing,box C/D snoRNP assembly","."]
["PURA","purine-rich element binding protein A [Source:HGNC Symbol;Acc:9701]","ENSG00000185129","ENSP00000332706",1,"PurA[1]","family-508","PURA,PURB,PURG","PURA","PURB[66,68],PURG[51,47]","mRNA","mRNA",11032866,"RNAbinding","RNArelated",1,1,1,".","GO:0000900","translation repressor activity, nucleic acid binding","GO:0005515,GO:0003700,GO:0003677,GO:0003690,GO:0003697,GO:0008134,GO:0003705,GO:0046332,GO:0003691,GO:0032422,GO:0000900,GO:0005662,GO:0005634,GO:0005737,GO:0043025,GO:0030425,GO:0000784,GO:0045892,GO:0008284,GO:0007399,GO:0006270,GO:0006268","protein binding,sequence-specific DNA binding transcription factor activity,DNA binding,double-stranded DNA binding,single-stranded DNA binding,transcription factor binding,RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity,SMAD binding,double-stranded telomeric DNA binding,purine-rich negative regulatory element binding,translation repressor activity, nucleic acid binding,DNA replication factor A complex,nucleus,cytoplasm,neuronal cell body,dendrite,nuclear chromosome, telomeric region,negative regulation of transcription, DNA-dependent,positive regulation of cell proliferation,nervous system development,DNA replication initiation,DNA unwinding involved in DNA replication","."]
["PURB","purine-rich element binding protein B [Source:HGNC Symbol;Acc:9702]","ENSG00000146676","ENSP00000379051",1,"PurA[1]","family-508","PURA,PURB,PURG","PURA","PURB[66,68],PURG[51,47]","mRNA","mRNA",11032866,"RNAbinding","RNAbinding",1,1,1,".","GO:0003729","mRNA binding","GO:0005515,GO:0003729,GO:0003697,GO:0008134,GO:0003700,GO:0003690,GO:0046332,GO:0005662,GO:0005634,GO:0006351,GO:0045892,GO:0045637","protein binding,mRNA binding,single-stranded DNA binding,transcription factor binding,sequence-specific DNA binding transcription factor activity,double-stranded DNA binding,SMAD binding,DNA replication factor A complex,nucleus,transcription, DNA-templated,negative regulation of transcription, DNA-dependent,regulation of myeloid cell differentiation","."]
["PURG","purine-rich element binding protein G [Source:HGNC Symbol;Acc:17930]","ENSG00000172733","ENSP00000345168",1,"PurA[1]","family-508","PURA,PURB,PURG","PURA","PURB[66,68],PURG[51,47]","mRNA","putative mRNA","by homology","RNAbinding",".",".",1,".",".",".",".","GO:0003677,GO:0005634","DNA binding,nucleus","."]
["ZRANB2","zinc finger, RAN-binding domain containing 2 [Source:HGNC Symbol;Acc:13058]","ENSG00000132485","ENSP00000254821",2,"zf-RanBP[2]","family-509","ZRANB2",".",".","mRNA","mRNA",19052380,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0003723,GO:0003700,GO:0005515,GO:0008270,GO:0005634,GO:0006355,GO:0006397,GO:0008380","RNA binding,sequence-specific DNA binding transcription factor activity,protein binding,zinc ion binding,nucleus,regulation of transcription, DNA-dependent,mRNA processing,RNA splicing","."]
["THOC5","THO complex 5 [Source:HGNC Symbol;Acc:19074]","ENSG00000100296","ENSP00000420306",1,"FimP[1]","family-51","THOC5",".",".","mRNA","mRNA",18373705,".",".",".",".",".",".","GO:0003723,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0006406","RNA binding,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0043231,GO:0045111,GO:0016607,GO:0000346,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0060215,GO:0006406,GO:0045650,GO:0030224,GO:0032786,GO:2000002,GO:0046784","RNA binding,protein binding,nucleus,cytoplasm,intracellular membrane-bounded organelle,intermediate filament cytoskeleton,nuclear speck,transcription export complex,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,primitive hemopoiesis,mRNA export from nucleus,negative regulation of macrophage differentiation,monocyte differentiation,positive regulation of DNA-dependent transcription, elongation,negative regulation of DNA damage checkpoint,viral mRNA export from host cell nucleus","."]
["TSEN54","tRNA splicing endonuclease 54 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:27561]","ENSG00000182173","ENSP00000327487",1,"tRNA_int_end_N2[1]","family-510","TSEN54",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0006397,GO:0006388","mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation","GO:0005730,GO:0006397,GO:0006388","nucleolus,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation"," PONTOCEREBELLAR HYPOPLASIA, TYPE 4; PCH4"]
["SRP9","signal recognition particle 9kDa [Source:HGNC Symbol;Acc:11304]","ENSG00000143742","ENSP00000355803",1,"SRP9-21[1]","family-511","SRP9",".",".","ncRNA","7SL","established RBP ",".",".",".",".",".",".","GO:0008312,GO:0003723,GO:0006412","7S RNA binding,RNA binding,translation","GO:0008312,GO:0048500,GO:0006614,GO:0045900,GO:0003723,GO:0005047,GO:0005829,GO:0005786,GO:0005785,GO:0006412,GO:0010467,GO:0044267","7S RNA binding,signal recognition particle,SRP-dependent cotranslational protein targeting to membrane,negative regulation of translational elongation,RNA binding,signal recognition particle binding,cytosol,signal recognition particle, endoplasmic reticulum targeting,signal recognition particle receptor complex,translation,gene expression,cellular protein metabolic process","."]
["PIN4","protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) [Source:HGNC Symbol;Acc:8992]","ENSG00000102309","ENSP00000362773",1,"Rotamase_3[1]","family-512","PIN4",".",".","rRNA","rRNA",19369196,"candidate mRNA binder",".",".",1,".",".","GO:0030684,GO:0006364","preribosome,rRNA processing","GO:0003677,GO:0003690,GO:0003755,GO:0003681,GO:0005634,GO:0005737,GO:0005759,GO:0005730,GO:0005819,GO:0030684,GO:0006457,GO:0006364,GO:0016853","DNA binding,double-stranded DNA binding,peptidyl-prolyl cis-trans isomerase activity,bent DNA binding,nucleus,cytoplasm,mitochondrial matrix,nucleolus,spindle,preribosome,protein folding,rRNA processing,isomerase activity","."]
["ZC3H14","zinc finger CCCH-type containing 14 [Source:HGNC Symbol;Acc:20509]","ENSG00000100722","ENSP00000452370",3,"zf-CCCH_2[3]","family-513","ZC3H14",".",".","mRNA","mRNA","ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007 [PubMed 17630287]).[supplied by OMIM, Mar 2010]","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0046872,GO:0005634,GO:0005737,GO:0016607","RNA binding,protein binding,metal ion binding,nucleus,cytoplasm,nuclear speck","."]
["CNOT2","CCR4-NOT transcription complex, subunit 2 [Source:HGNC Symbol;Acc:7878]","ENSG00000111596","ENSP00000446507",1,"NOT2_3_5[1]","family-514","CNOT2",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0004535,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047","poly(A)-specific ribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA","GO:0005515,GO:0001104,GO:0004535,GO:0001226,GO:0005634,GO:0005737,GO:0005829,GO:0030014,GO:0000122,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047,GO:0033147,GO:2000036,GO:0006357,GO:0001829","protein binding,RNA polymerase II transcription cofactor activity,poly(A)-specific ribonuclease activity,RNA polymerase II transcription corepressor binding,nucleus,cytoplasm,cytosol,CCR4-NOT complex,negative regulation of transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA,negative regulation of intracellular estrogen receptor signaling pathway,regulation of stem cell maintenance,regulation of transcription from RNA polymerase II promoter,trophectodermal cell differentiation","."]
["TARBP1","TAR (HIV-1) RNA binding protein 1 [Source:HGNC Symbol;Acc:11568]","ENSG00000059588","ENSP00000040877",1,"SpoU_methylase[1]","family-515","TARBP1",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0008173,GO:0006396","RNA binding,RNA methyltransferase activity,RNA processing","GO:0005488,GO:0003723,GO:0008173,GO:0005634,GO:0006357,GO:0006396","binding,RNA binding,RNA methyltransferase activity,nucleus,regulation of transcription from RNA polymerase II promoter,RNA processing","."]
["AGO1","eukaryotic translation initiation factor 2C, 1 [Source:HGNC Symbol;Acc:3262]","ENSG00000092847","ENSP00000362300",3,"DUF1785[1],PAZ[1],Piwi[1]","family-516","AGO1,AGO2,AGO3,AGO4","AGO1","AGO2[82,82],AGO3[85,84],AGO4[84,83]","ncRNA","miRNA/mRNA","established RBP ","translationfactor",".",".",1,".",".","GO:0003723,GO:0000932,GO:0030529,GO:0035068,GO:0000956","RNA binding,cytoplasmic mRNA processing body,ribonucleoprotein complex,micro-ribonucleoprotein complex,nuclear-transcribed mRNA catabolic process","GO:0005515,GO:0003723,GO:0003676,GO:0005737,GO:0005829,GO:0000932,GO:0030529,GO:0005844,GO:0035068,GO:0006351,GO:0038095,GO:0045087,GO:0006355,GO:0048015,GO:0010467,GO:0007219,GO:0008543,GO:0007173,GO:0048011,GO:0035278,GO:0000956","protein binding,RNA binding,nucleic acid binding,cytoplasm,cytosol,cytoplasmic mRNA processing body,ribonucleoprotein complex,polysome,micro-ribonucleoprotein complex,transcription, DNA-templated,Fc-epsilon receptor signaling pathway,innate immune response,regulation of transcription, DNA-dependent,phosphatidylinositol-mediated signaling,gene expression,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,negative regulation of translation involved in gene silencing by miRNA,nuclear-transcribed mRNA catabolic process","."]
["AGO2","eukaryotic translation initiation factor 2C, 2 [Source:HGNC Symbol;Acc:3263]","ENSG00000123908","ENSP00000220592",3,"DUF1785[1],PAZ[1],Piwi[1]","family-516","AGO1,AGO2,AGO3,AGO4","AGO1","AGO2[82,82],AGO3[85,84],AGO4[84,83]","ncRNA","miRNA/mRNA","established RBP ","translationfactor","RNAbinding",1,1,1,".","GO:0003729,GO:0004521,GO:0000932,GO:0031047,GO:0060213,GO:1900153,GO:0006379,GO:0003743,GO:0035197,GO:0035198,GO:0000340,GO:0070551,GO:0030529,GO:0005845,GO:0035068,GO:0006412,GO:0031054,GO:0006413,GO:0035279,GO:0003723","mRNA binding,endoribonuclease activity,cytoplasmic mRNA processing body,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA cleavage,translation initiation factor activity,siRNA binding,miRNA binding,RNA 7-methylguanosine cap binding,endoribonuclease activity, cleaving siRNA-paired mRNA,ribonucleoprotein complex,mRNA cap binding complex,micro-ribonucleoprotein complex,translation,pre-miRNA processing,translational initiation,mRNA cleavage involved in gene silencing by miRNA,RNA binding","GO:0005515,GO:0003729,GO:0004521,GO:0000932,GO:0031047,GO:0060213,GO:1900153,GO:0009791,GO:0006379,GO:0003676,GO:0046872,GO:0003743,GO:0035197,GO:0035198,GO:0000340,GO:0070551,GO:0005634,GO:0005737,GO:0005829,GO:0030529,GO:0005845,GO:0005844,GO:0016442,GO:0035068,GO:0006351,GO:0038095,GO:0045087,GO:0006412,GO:0006355,GO:0048015,GO:0010467,GO:0007219,GO:0008543,GO:0007173,GO:0031054,GO:0048011,GO:0045947,GO:0035278,GO:0006413,GO:0035279,GO:0003723","protein binding,mRNA binding,endoribonuclease activity,cytoplasmic mRNA processing body,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,post-embryonic development,mRNA cleavage,nucleic acid binding,metal ion binding,translation initiation factor activity,siRNA binding,miRNA binding,RNA 7-methylguanosine cap binding,endoribonuclease activity, cleaving siRNA-paired mRNA,nucleus,cytoplasm,cytosol,ribonucleoprotein complex,mRNA cap binding complex,polysome,RISC complex,micro-ribonucleoprotein complex,transcription, DNA-templated,Fc-epsilon receptor signaling pathway,innate immune response,translation,regulation of transcription, DNA-dependent,phosphatidylinositol-mediated signaling,gene expression,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,epidermal growth factor receptor signaling pathway,pre-miRNA processing,neurotrophin TRK receptor signaling pathway,negative regulation of translational initiation,negative regulation of translation involved in gene silencing by miRNA,translational initiation,mRNA cleavage involved in gene silencing by miRNA,RNA binding","."]
["AGO3","eukaryotic translation initiation factor 2C, 3 [Source:HGNC Symbol;Acc:18421]","ENSG00000126070","ENSP00000362287",3,"DUF1785[1],PAZ[1],Piwi[1]","family-516","AGO1,AGO2,AGO3,AGO4","AGO1","AGO2[82,82],AGO3[85,84],AGO4[84,83]","ncRNA","miRNA/mRNA","established RBP ","translationfactor","experimentally validated",1,1,".",".","GO:0003743,GO:0035198,GO:0000932,GO:0035068,GO:0006402,GO:0003723","translation initiation factor activity,miRNA binding,cytoplasmic mRNA processing body,micro-ribonucleoprotein complex,mRNA catabolic process,RNA binding","GO:0005515,GO:0003743,GO:0003676,GO:0035198,GO:0005829,GO:0000932,GO:0016442,GO:0035068,GO:0038095,GO:0045087,GO:0048015,GO:0010467,GO:0007219,GO:0008543,GO:0006402,GO:0007173,GO:0048011,GO:0035278,GO:0072091,GO:0003723","protein binding,translation initiation factor activity,nucleic acid binding,miRNA binding,cytosol,cytoplasmic mRNA processing body,RISC complex,micro-ribonucleoprotein complex,Fc-epsilon receptor signaling pathway,innate immune response,phosphatidylinositol-mediated signaling,gene expression,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,mRNA catabolic process,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,negative regulation of translation involved in gene silencing by miRNA,regulation of stem cell proliferation,RNA binding","."]
["AGO4","eukaryotic translation initiation factor 2C, 4 [Source:HGNC Symbol;Acc:18424]","ENSG00000134698","ENSP00000362306",3,"DUF1785[1],PAZ[1],Piwi[1]","family-516","AGO1,AGO2,AGO3,AGO4","AGO1","AGO2[82,82],AGO3[85,84],AGO4[84,83]","ncRNA","miRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0035198,GO:0000932,GO:0035068,GO:0006402","RNA binding,miRNA binding,cytoplasmic mRNA processing body,micro-ribonucleoprotein complex,mRNA catabolic process","GO:0003723,GO:0005515,GO:0003676,GO:0035198,GO:0005829,GO:0000932,GO:0016442,GO:0035068,GO:0038095,GO:0045087,GO:0048015,GO:0010467,GO:0007219,GO:0008543,GO:0006402,GO:0007173,GO:0048011,GO:0035278","RNA binding,protein binding,nucleic acid binding,miRNA binding,cytosol,cytoplasmic mRNA processing body,RISC complex,micro-ribonucleoprotein complex,Fc-epsilon receptor signaling pathway,innate immune response,phosphatidylinositol-mediated signaling,gene expression,Notch signaling pathway,fibroblast growth factor receptor signaling pathway,mRNA catabolic process,epidermal growth factor receptor signaling pathway,neurotrophin TRK receptor signaling pathway,negative regulation of translation involved in gene silencing by miRNA","."]
["LARP4B","La ribonucleoprotein domain family, member 4B [Source:HGNC Symbol;Acc:28987]","ENSG00000107929","ENSP00000326128",2,"La[1],RRM_5[1]","family-517","LARP4,LARP4B","LARP4","LARP4B[35,35]","mRNA","mRNA",20573744,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0010494,GO:0042788,GO:0045727","RNA binding,cytoplasmic stress granule,polysomal ribosome,positive regulation of translation","GO:0003723,GO:0005829,GO:0010494,GO:0042788,GO:0045727","RNA binding,cytosol,cytoplasmic stress granule,polysomal ribosome,positive regulation of translation","."]
["LARP4","La ribonucleoprotein domain family, member 4 [Source:HGNC Symbol;Acc:24320]","ENSG00000161813","ENSP00000293618",2,"La[1],RRM_6[1]","family-517","LARP4,LARP4B","LARP4","LARP4B[35,35]","mRNA","mRNA",21098120,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0007010,GO:0022604,GO:0003676","RNA binding,cytoskeleton organization,regulation of cell morphogenesis,nucleic acid binding","."]
["SNW1","SNW domain containing 1 [Source:HGNC Symbol;Acc:16696] [Type: protein coding Ensembl/Havana merge]","ENSG00000100603","ENSP00000261531",1,"SKIP_SNW[1]","family-518","SNW1",".",".","mRNA","putative mRNA/snRNA"," It can also function as a splicing factor by interacting with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. [provided by RefSeq, Jul 2008]","candidate mRNA binder",".",".",1,".",".","GO:0005681,GO:0000398,GO:0071013,GO:0048026","spliceosomal complex,mRNA splicing, via spliceosome,catalytic step 2 spliceosome,positive regulation of mRNA splicing, via spliceosome","GO:0005681,GO:0000398,GO:0005525,GO:0005634,GO:0006614,GO:0000785,GO:0005515,GO:0003714,GO:0042974,GO:0042809,GO:0003713,GO:0046332,GO:0005112,GO:0035257,GO:0005654,GO:0016363,GO:0071013,GO:0008024,GO:0071146,GO:0000122,GO:0045944,GO:0045892,GO:0010467,GO:0006357,GO:0006367,GO:0007219,GO:0051571,GO:0050769,GO:0071300,GO:0042771,GO:0030511,GO:0048384,GO:0048026,GO:0019048,GO:0070562,GO:0070564,GO:0043923,GO:0048385","spliceosomal complex,mRNA splicing, via spliceosome,GTP binding,nucleus,SRP-dependent cotranslational protein targeting to membrane,chromatin,protein binding,transcription corepressor activity,retinoic acid receptor binding,vitamin D receptor binding,transcription coactivator activity,SMAD binding,Notch binding,nuclear hormone receptor binding,nucleoplasm,nuclear matrix,catalytic step 2 spliceosome,positive transcription elongation factor complex b,SMAD3-SMAD4 protein complex,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,negative regulation of transcription, DNA-dependent,gene expression,regulation of transcription from RNA polymerase II promoter,transcription initiation from RNA polymerase II promoter,Notch signaling pathway,positive regulation of histone H3-K4 methylation,positive regulation of neurogenesis,cellular response to retinoic acid,intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,positive regulation of transforming growth factor beta receptor signaling pathway,retinoic acid receptor signaling pathway,positive regulation of mRNA splicing, via spliceosome,modulation by virus of host morphology or physiology,regulation of vitamin D receptor signaling pathway,positive regulation of vitamin D receptor signaling pathway,positive regulation by host of viral transcription,regulation of retinoic acid receptor signaling pathway","."]
["EZH2","enhancer of zeste homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:3527]","ENSG00000106462","ENSP00000320147",2,"SET[1],EZH2_WD-Binding[1]","family-519","EZH1,EZH2","EZH1","EZH2[65,65]","ncRNA","lincRNA",24320048,".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003682,GO:0003723,GO:0001047,GO:0005515,GO:0003677,GO:0018024,GO:0043565,GO:0042054,GO:0035098,GO:0045120,GO:0000122,GO:0006351,GO:2000134,GO:0045892,GO:0034244,GO:0006355,GO:0048387,GO:0042127,GO:0043406,GO:0071902,GO:0070314,GO:0021695,GO:0006325,GO:0010718,GO:0032320,GO:0045814,GO:0051154,GO:0014013,GO:0045605,GO:0070734,GO:0000975,GO:0005737,GO:0005634,GO:0010468,GO:0050767,GO:0016571,GO:0001932,GO:0010629","chromatin binding,RNA binding,core promoter binding,protein binding,DNA binding,histone-lysine N-methyltransferase activity,sequence-specific DNA binding,histone methyltransferase activity,ESC/E(Z) complex,pronucleus,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,negative regulation of G1/S transition of mitotic cell cycle,negative regulation of transcription, DNA-dependent,negative regulation of transcription elongation from RNA polymerase II promoter,regulation of transcription, DNA-dependent,negative regulation of retinoic acid receptor signaling pathway,regulation of cell proliferation,positive regulation of MAP kinase activity,positive regulation of protein serine/threonine kinase activity,G1 to G0 transition,cerebellar cortex development,chromatin organization,positive regulation of epithelial to mesenchymal transition,positive regulation of Ras GTPase activity,negative regulation of gene expression, epigenetic,negative regulation of striated muscle cell differentiation,regulation of gliogenesis,negative regulation of epidermal cell differentiation,histone H3-K27 methylation,regulatory region DNA binding,cytoplasm,nucleus,regulation of gene expression,regulation of neurogenesis,histone methylation,regulation of protein phosphorylation,negative regulation of gene expression"," WEAVER SYNDROME; WVS"]
["EIF3B","eukaryotic translation initiation factor 3, subunit B [Source:HGNC Symbol;Acc:3280]","ENSG00000106263","ENSP00000354125",3,"eIF2A[2],RRM_1[1]","family-52","EIF3B",".",".","mRNA","mRNA",17190833,".",".",".",".",".",1,"GO:0003723,GO:0003743,GO:0031369,GO:0005852,GO:0016282,GO:0033290,GO:0006412,GO:0001731,GO:0006446,GO:0006413","RNA binding,translation initiation factor activity,translation initiation factor binding,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003743,GO:0032947,GO:0031369,GO:0005829,GO:0005852,GO:0016282,GO:0033290,GO:0006412,GO:0010467,GO:0001731,GO:0006446,GO:0044267,GO:0006413","nucleotide binding,RNA binding,protein binding,nucleic acid binding,translation initiation factor activity,protein complex scaffold,translation initiation factor binding,cytosol,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translation,gene expression,formation of translation preinitiation complex,regulation of translational initiation,cellular protein metabolic process,translational initiation","."]
["RPP30","ribonuclease P/MRP 30kDa subunit [Source:HGNC Symbol;Acc:17688]","ENSG00000148688","ENSP00000389182",2,"GVQW[1],RNase_P_p30[1]","family-520","RPP30",".",".","ncRNA","P/MRP RNA","RPP1 yeast homolog",".","RNArelated",".",1,1,".","GO:0004540,GO:0004526,GO:0005655,GO:0008033","ribonuclease activity,ribonuclease P activity,nucleolar ribonuclease P complex,tRNA processing","GO:0003824,GO:0004540,GO:0004526,GO:0005634,GO:0005655,GO:0008033","catalytic activity,ribonuclease activity,ribonuclease P activity,nucleus,nucleolar ribonuclease P complex,tRNA processing","."]
["ZMAT3","zinc finger, matrin-type 3 [Source:HGNC Symbol;Acc:29983]","ENSG00000172667","ENSP00000311221",3,"zf-C2H2_jaz[1],zf-met[2]","family-521","ZMAT3",".",".","ncRNA","viral RNA/small dsRNA miRNA/siRNA type","16844115, 22513872",".","RNAbinding",".",1,1,".","GO:0003723","RNA binding","GO:0008270,GO:0003676,GO:0005730,GO:0003723,GO:0005515,GO:0006915,GO:0006974,GO:0015031,GO:0040008,GO:0043065","zinc ion binding,nucleic acid binding,nucleolus,RNA binding,protein binding,apoptotic process,cellular response to DNA damage stimulus,protein transport,regulation of growth,positive regulation of apoptotic process","."]
["PTGES3","prostaglandin E synthase 3 (cytosolic) [Source:HGNC Symbol;Acc:16049]","ENSG00000110958","ENSP00000262033",1,"CS[1]","family-522","PTGES3,PTGES3L","PTGES3","PTGES3L[29,29]","ncRNA","teloRNA",12135483,".",".",".",".",".",".","GO:0003720,GO:0005697","telomerase activity,telomerase holoenzyme complex","GO:0005634,GO:0005737,GO:0005515,GO:0051082,GO:0050220,GO:0003720,GO:0005829,GO:0000781,GO:0005697,GO:0044281,GO:0007165,GO:0000723,GO:0019369,GO:0070389,GO:0001516,GO:0019371","nucleus,cytoplasm,protein binding,unfolded protein binding,prostaglandin-E synthase activity,telomerase activity,cytosol,chromosome, telomeric region,telomerase holoenzyme complex,small molecule metabolic process,signal transduction,telomere maintenance,arachidonic acid metabolic process,chaperone cofactor-dependent protein refolding,prostaglandin biosynthetic process,cyclooxygenase pathway","."]
["KARS","lysyl-tRNA synthetase [Source:HGNC Symbol;Acc:6215]","ENSG00000065427","ENSP00000462057",2,"tRNA-synt_2[1],tRNA_anti-codon[1]","family-523","KARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000049,GO:0004824,GO:0017101,GO:0006430,GO:0004812,GO:0006418,GO:0008033","tRNA binding,lysine-tRNA ligase activity,aminoacyl-tRNA synthetase multienzyme complex,lysyl-tRNA aminoacylation,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,tRNA processing","GO:0005524,GO:0003676,GO:0000049,GO:0016597,GO:0004824,GO:0017101,GO:0006430,GO:0015966,GO:0000166,GO:0004812,GO:0006418,GO:0005515,GO:0046872,GO:0005634,GO:0005886,GO:0005737,GO:0005576,GO:0005739,GO:0005829,GO:0005759,GO:0015630,GO:0010467,GO:0008033,GO:0019048","ATP binding,nucleic acid binding,tRNA binding,amino acid binding,lysine-tRNA ligase activity,aminoacyl-tRNA synthetase multienzyme complex,lysyl-tRNA aminoacylation,diadenosine tetraphosphate biosynthetic process,nucleotide binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,protein binding,metal ion binding,nucleus,plasma membrane,cytoplasm,extracellular region,mitochondrion,cytosol,mitochondrial matrix,microtubule cytoskeleton,gene expression,tRNA processing,modulation by virus of host morphology or physiology"," CHARCOT-MARIE-TOOTH DISEASE, RECESSIVE INTERMEDIATE B; CMTRIB"]
["RAN","RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:9846]","ENSG00000132341","ENSP00000446215",1,"Ras[1]","family-524","RAN",".",".","mRNA","putative mRNA","RNA export","candidate mRNA binder","RNArelated",1,1,".",".","GO:0006405","RNA export from nucleus","GO:0005525,GO:0003924,GO:0005634,GO:0005737,GO:0007264,GO:0015031,GO:0007165,GO:0030036,GO:0006886,GO:0006606,GO:0034629,GO:0006913,GO:0006184,GO:0016020,GO:0005622,GO:0005515,GO:0003682,GO:0003713,GO:0050681,GO:0005829,GO:0005654,GO:0000785,GO:0005643,GO:0042470,GO:0045893,GO:0007067,GO:0044281,GO:0006611,GO:0016032,GO:0010467,GO:0032092,GO:0006259,GO:0030521,GO:0019048,GO:0019058,GO:0007052,GO:0075733,GO:0006405,GO:0019904","GTP binding,GTPase activity,nucleus,cytoplasm,small GTPase mediated signal transduction,protein transport,signal transduction,actin cytoskeleton organization,intracellular protein transport,protein import into nucleus,cellular protein complex localization,nucleocytoplasmic transport,GTP catabolic process,membrane,intracellular,protein binding,chromatin binding,transcription coactivator activity,androgen receptor binding,cytosol,nucleoplasm,chromatin,nuclear pore,melanosome,positive regulation of transcription, DNA-dependent,mitosis,small molecule metabolic process,protein export from nucleus,viral process,gene expression,positive regulation of protein binding,DNA metabolic process,androgen receptor signaling pathway,modulation by virus of host morphology or physiology,viral life cycle,mitotic spindle organization,intracellular transport of virus,RNA export from nucleus,protein domain specific binding","."]
["SNRPA","small nuclear ribonucleoprotein polypeptide A [Source:HGNC Symbol;Acc:11151]","ENSG00000077312","ENSP00000243563",2,"RRM_1[2]","family-525","SNRPA,SNRPB2","SNRPA","SNRPB2[55,68]","snRNA","snRNA/mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0017069,GO:0000398,GO:0003723,GO:0005681,GO:0008380","snRNA binding,mRNA splicing, via spliceosome,RNA binding,spliceosomal complex,RNA splicing","GO:0000166,GO:0003676,GO:0017069,GO:0000398,GO:0003723,GO:0005515,GO:0005654,GO:0005681,GO:0010467,GO:0008380","nucleotide binding,nucleic acid binding,snRNA binding,mRNA splicing, via spliceosome,RNA binding,protein binding,nucleoplasm,spliceosomal complex,gene expression,RNA splicing","."]
["SNRPB2","small nuclear ribonucleoprotein polypeptide B [Source:HGNC Symbol;Acc:11155]","ENSG00000125870","ENSP00000246071",2,"RRM_5[1],RRM_1[1]","family-525","SNRPA,SNRPB2","SNRPA","SNRPB2[55,68]","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0017069,GO:0005681,GO:0005686,GO:0071013,GO:0006397,GO:0008380,GO:0000398","snRNA binding,spliceosomal complex,U2 snRNP,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","GO:0005515,GO:0000166,GO:0003676,GO:0017069,GO:0005654,GO:0005681,GO:0005686,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398","protein binding,nucleotide binding,nucleic acid binding,snRNA binding,nucleoplasm,spliceosomal complex,U2 snRNP,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","."]
["HEATR1","HEAT repeat containing 1 [Source:HGNC Symbol;Acc:25517]","ENSG00000119285","ENSP00000355541",3,"BP28CT[1],DUF2435[1],U3snoRNP10[1]","family-526","HEATR1",".",".","snoRNA","putative snoRNA","UTP10 yeast homolog","candidate mRNA binder","RNArelated",1,1,".",".","GO:0030529,GO:0006364","ribonucleoprotein complex,rRNA processing","GO:0005488,GO:0005634,GO:0005739,GO:0005730,GO:0005515,GO:0030529,GO:0006364","binding,nucleus,mitochondrion,nucleolus,protein binding,ribonucleoprotein complex,rRNA processing","."]
["PTGES3L-AARSD1","PTGES3L-AARSD1 readthrough [Source:HGNC Symbol;Acc:43946]","ENSG00000108825","ENSP00000409924",3,"tRNA_SAD[1],CS[1],tRNA-synt_2c[1]","family-527","AARSD1,PTGES3L-AARSD1","AARSD1","PTGES3L-AARSD1[93,66]","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0004813,GO:0006419,GO:0016876,GO:0043039","alanine-tRNA ligase activity,alanyl-tRNA aminoacylation,ligase activity, forming aminoacyl-tRNA and related compounds,tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004813,GO:0006419,GO:0003676,GO:0046872,GO:0016876,GO:0005737,GO:0043039","nucleotide binding,ATP binding,alanine-tRNA ligase activity,alanyl-tRNA aminoacylation,nucleic acid binding,metal ion binding,ligase activity, forming aminoacyl-tRNA and related compounds,cytoplasm,tRNA aminoacylation","."]
["AARSD1","alanyl-tRNA synthetase domain containing 1 [Source:HGNC Symbol;Acc:28417]","ENSG00000266967","ENSP00000400870",2,"tRNA_SAD[1],tRNA-synt_2c[1]","family-527","AARSD1,PTGES3L-AARSD1","AARSD1","PTGES3L-AARSD1[93,66]","tRNA","putative tRNA","established RBP ",".",".",".",".",".",".","GO:0016876,GO:0043039,GO:0002161,GO:0004813,GO:0006450,GO:0006419","ligase activity, forming aminoacyl-tRNA and related compounds,tRNA aminoacylation,aminoacyl-tRNA editing activity,alanine-tRNA ligase activity,regulation of translational fidelity,alanyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0016876,GO:0043039,GO:0005515,GO:0002161,GO:0002196,GO:0003676,GO:0046872,GO:0004813,GO:0005737,GO:0006450,GO:0006419","nucleotide binding,ATP binding,ligase activity, forming aminoacyl-tRNA and related compounds,tRNA aminoacylation,protein binding,aminoacyl-tRNA editing activity,Ser-tRNA(Ala) hydrolase activity,nucleic acid binding,metal ion binding,alanine-tRNA ligase activity,cytoplasm,regulation of translational fidelity,alanyl-tRNA aminoacylation","."]
["CPSF3","cleavage and polyadenylation specific factor 3, 73kDa [Source:HGNC Symbol;Acc:2326]","ENSG00000119203","ENSP00000238112",4,"RMMBL[1],Beta-Casp[1],Lactamase_B[1],CPSF73-100_C[1]","family-528","CPSF3,CPSF3L","CPSF3","CPSF3L[29,32]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004521,GO:0008409,GO:0006398,GO:0030529,GO:0005847,GO:0008380,GO:0000398,GO:0006379,GO:0006406,GO:0031124,GO:0006378","RNA binding,endoribonuclease activity,5'-3' exonuclease activity,histone mRNA 3'-end processing,ribonucleoprotein complex,mRNA cleavage and polyadenylation specificity factor complex,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA export from nucleus,mRNA 3'-end processing,mRNA polyadenylation","GO:0003723,GO:0016787,GO:0004521,GO:0008409,GO:0006398,GO:0005515,GO:0046872,GO:0005654,GO:0030529,GO:0005847,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006379,GO:0006406,GO:0031124,GO:0006378,GO:0006369","RNA binding,hydrolase activity,endoribonuclease activity,5'-3' exonuclease activity,histone mRNA 3'-end processing,protein binding,metal ion binding,nucleoplasm,ribonucleoprotein complex,mRNA cleavage and polyadenylation specificity factor complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA export from nucleus,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription","."]
["CPSF3L","cleavage and polyadenylation specific factor 3-like [Source:HGNC Symbol;Acc:26052]","ENSG00000127054","ENSP00000392848",3,"RMMBL[1],Beta-Casp[1],Lactamase_B[1]","family-528","CPSF3,CPSF3L","CPSF3","CPSF3L[29,32]","mRNA","mRNA","established RBP ",".",".",".",".",".",".",".",".","GO:0016787,GO:0005634,GO:0005737","hydrolase activity,nucleus,cytoplasm","."]
["CWC25","CWC25 spliceosome-associated protein homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25989]","ENSG00000108296","ENSP00000225428",2,"Cir_N[1],CWC25[1]","family-529","CWC25",".",".","mRNA","mRNA","This gene encodes a factor that is part of the multi-protein C complex involved in pre-mRNA splicing. Alternatively spliced transcripts have been described for this gene. [provided by RefSeq, Nov 2012]",".",".",".",".",".",".",".",".",".",".","."]
["RPS5","ribosomal protein S5 [Source:HGNC Symbol;Acc:10426]","ENSG00000083845","ENSP00000196551",1,"Ribosomal_S7[1]","family-53","RPS5",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0003729,GO:0022627,GO:0030529,GO:0015935,GO:0006412,GO:0016070,GO:0016071,GO:0006450,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,mRNA binding,cytosolic small ribosomal subunit,ribonucleoprotein complex,small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,regulation of translational fidelity,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0003729,GO:0005829,GO:0022627,GO:0030529,GO:0015935,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006450,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,mRNA binding,cytosol,cytosolic small ribosomal subunit,ribonucleoprotein complex,small ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,regulation of translational fidelity,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["POLR2D","polymerase (RNA) II (DNA directed) polypeptide D [Source:HGNC Symbol;Acc:9191]","ENSG00000144231","ENSP00000272645",1,"RNA_pol_Rpb4[1]","family-530","POLR2D",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0000166,GO:0003824,GO:0003899,GO:0006351,GO:0044237,GO:0005634,GO:0005654,GO:0005665,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","nucleotide binding,catalytic activity,DNA-directed RNA polymerase activity,transcription, DNA-templated,cellular metabolic process,nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["C9orf114","chromosome 9 open reading frame 114 [Source:HGNC Symbol;Acc:26933]","ENSG00000198917","ENSP00000354812",1,"Methyltrn_RNA_3[1]","family-531","C9orf114",".",".","unknown","unknown","established RBP ","candidate mRNA binder","novel",1,1,1,".",".",".",".",".","."]
["MRPL44","mitochondrial ribosomal protein L44 [Source:HGNC Symbol;Acc:16650]","ENSG00000135900","ENSP00000258383",1,"dsrm[1]","family-532","MRPL44",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003723,GO:0004525,GO:0005840,GO:0006396","RNA binding,ribonuclease III activity,ribosome,RNA processing","GO:0003723,GO:0004525,GO:0005739,GO:0005840,GO:0006396","RNA binding,ribonuclease III activity,mitochondrion,ribosome,RNA processing","."]
["ETF1","eukaryotic translation termination factor 1 [Source:HGNC Symbol;Acc:3477]","ENSG00000120705","ENSP00000353741",3,"eRF1_1[1],eRF1_2[1],eRF1_3[1]","family-533","ETF1",".",".","mRNA","mRNA","This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]",".","RNAbinding",".",1,1,".","GO:0016149,GO:0006415,GO:0003723,GO:0043022,GO:0003747,GO:0008079,GO:0006412,GO:0016070,GO:0016071,GO:0000184,GO:0006449","translation release factor activity, codon specific,translational termination,RNA binding,ribosome binding,translation release factor activity,translation termination factor activity,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of translational termination","GO:0016149,GO:0005737,GO:0006415,GO:0003723,GO:0005515,GO:0043022,GO:0003747,GO:0008079,GO:0005829,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0006479,GO:0044267,GO:0000184,GO:0006449","translation release factor activity, codon specific,cytoplasm,translational termination,RNA binding,protein binding,ribosome binding,translation release factor activity,translation termination factor activity,cytosol,translation,gene expression,RNA metabolic process,mRNA metabolic process,protein methylation,cellular protein metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of translational termination","."]
["GAR1","GAR1 ribonucleoprotein homolog (yeast) [Source:HGNC Symbol;Acc:14264]","ENSG00000109534","ENSP00000226796",1,"Gar1[1]","family-534","GAR1",".",".","snoRNA","snoRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0031429,GO:0042254,GO:0006364","RNA binding,box H/ACA snoRNP complex,ribosome biogenesis,rRNA processing","GO:0003723,GO:0005261,GO:0015030,GO:0031429,GO:0042254,GO:0006364,GO:0001522","RNA binding,cation channel activity,Cajal body,box H/ACA snoRNP complex,ribosome biogenesis,rRNA processing,pseudouridine synthesis","."]
["MVP","major vault protein [Source:HGNC Symbol;Acc:7531]","ENSG00000013364","ENSP00000378760",6,"MVP_shoulder[1],Vault[5]","family-535","MVP",".",".","ncRNA","vtRNA","This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]",".",".",".",".",".",".","GO:0030529,GO:0051028","ribonucleoprotein complex,mRNA transport","GO:0005515,GO:0019901,GO:0019903,GO:0005634,GO:0005737,GO:0048471,GO:0005856,GO:0005643,GO:0030529,GO:0070062,GO:0008283,GO:0015031,GO:0051028,GO:0072376,GO:0031953,GO:0061099,GO:0038127,GO:0023057","protein binding,protein kinase binding,protein phosphatase binding,nucleus,cytoplasm,perinuclear region of cytoplasm,cytoskeleton,nuclear pore,ribonucleoprotein complex,extracellular vesicular exosome,cell proliferation,protein transport,mRNA transport,protein activation cascade,negative regulation of protein autophosphorylation,negative regulation of protein tyrosine kinase activity,ERBB signaling pathway,negative regulation of signaling","."]
["RPF2","ribosome production factor 2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20870]","ENSG00000197498","ENSP00000402338",1,"Brix[1]","family-536","RPF2",".",".","rRNA","putative rRNA",12048200,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0005634,GO:0005730","nucleus,nucleolus","."]
["ZC3H18","zinc finger CCCH-type containing 18 [Source:HGNC Symbol;Acc:25091]","ENSG00000158545","ENSP00000455260",1,"zf-CCCH[1]","family-537","ZC3H18",".",".","unknown","unknown","by homology","RNAbinding","novel",1,1,1,1,".",".","GO:0046872,GO:0005634","metal ion binding,nucleus","."]
["INTS5","integrator complex subunit 5 [Source:HGNC Symbol;Acc:29352]","ENSG00000185085","ENSP00000327889",2,"INTS5_C[1],INTS5_N[1]","family-538","INTS5",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0016021,GO:0032039,GO:0016180","protein binding,integral to membrane,integrator complex,snRNA processing","."]
["INTS3","integrator complex subunit 3 [Source:HGNC Symbol;Acc:26153]","ENSG00000143624","ENSP00000398222",1,"DUF2356[1]","family-539","INTS3",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0005634,GO:0032039,GO:0070876,GO:0006974,GO:0006281,GO:0010212,GO:0007093,GO:0016180","protein binding,nucleus,integrator complex,SOSS complex,cellular response to DNA damage stimulus,DNA repair,response to ionizing radiation,mitotic cell cycle checkpoint,snRNA processing","."]
["LSM6","LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:17017]","ENSG00000164167","ENSP00000296581",1,"LSM[1]","family-54","LSM6,SNRPF","LSM6","SNRPF[44,41]","snRNA","snRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0005681,GO:0030532,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0043928","RNA binding,spliceosomal complex,small nuclear ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,rRNA processing,tRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0005829,GO:0005681,GO:0030532,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0043928","RNA binding,protein binding,cytosol,spliceosomal complex,small nuclear ribonucleoprotein complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,rRNA processing,tRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["SNRPF","small nuclear ribonucleoprotein polypeptide F [Source:HGNC Symbol;Acc:11162]","ENSG00000139343","ENSP00000447751",1,"LSM[1]","family-54","LSM6,SNRPF","LSM6","SNRPF[44,41]","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0016070,GO:0008380,GO:0000398,GO:0006396,GO:0031124,GO:0000387,GO:0034660,GO:0008334","RNA binding,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,RNA processing,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,histone mRNA metabolic process","GO:0003723,GO:0005515,GO:0005634,GO:0005829,GO:0005654,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0006366,GO:0010467,GO:0016070,GO:0008380,GO:0000398,GO:0006396,GO:0031124,GO:0000387,GO:0034660,GO:0006369,GO:0008334","RNA binding,protein binding,nucleus,cytosol,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,RNA processing,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["TUT1","terminal uridylyl transferase 1, U6 snRNA-specific [Source:HGNC Symbol;Acc:26184]","ENSG00000149016","ENSP00000308000",3,"PAP_assoc[1],zf-met[1],RRM_6[1]","family-540","MTPAP,TUT1","MTPAP","TUT1[27,17]","snRNA","snRNA/miRNA","23874977, 9628908",".",".",".",".",".",1,"GO:0003723,GO:0003730,GO:0050265,GO:0005847,GO:0006379,GO:0016180,GO:0006378","RNA binding,mRNA 3'-UTR binding,RNA uridylyltransferase activity,mRNA cleavage and polyadenylation specificity factor complex,mRNA cleavage,snRNA processing,mRNA polyadenylation","GO:0000166,GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0046872,GO:0019899,GO:0003730,GO:0004652,GO:0050265,GO:0005730,GO:0016607,GO:0005847,GO:0006379,GO:0016180,GO:0006378","nucleotide binding,RNA binding,protein binding,ATP binding,nucleic acid binding,metal ion binding,enzyme binding,mRNA 3'-UTR binding,polynucleotide adenylyltransferase activity,RNA uridylyltransferase activity,nucleolus,nuclear speck,mRNA cleavage and polyadenylation specificity factor complex,mRNA cleavage,snRNA processing,mRNA polyadenylation","."]
["MTPAP","mitochondrial poly(A) polymerase [Source:HGNC Symbol;Acc:25532]","ENSG00000107951","ENSP00000350820",2,"GOLGA2L5[1],PAP_assoc[1]","family-540","MTPAP,TUT1","MTPAP","TUT1[27,17]","mRNA","mRNA","This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011]","RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0006378,GO:0071044","RNA binding,mRNA polyadenylation,histone mRNA catabolic process","GO:0003723,GO:0005515,GO:0042803,GO:0005524,GO:0000287,GO:0042802,GO:0030145,GO:0004652,GO:0002134,GO:0005634,GO:0005886,GO:0005737,GO:0005739,GO:0005794,GO:0006351,GO:0008219,GO:0006378,GO:0071044","RNA binding,protein binding,protein homodimerization activity,ATP binding,magnesium ion binding,identical protein binding,manganese ion binding,polynucleotide adenylyltransferase activity,UTP binding,nucleus,plasma membrane,cytoplasm,mitochondrion,Golgi apparatus,transcription, DNA-templated,cell death,mRNA polyadenylation,histone mRNA catabolic process"," SPASTIC ATAXIA 4, AUTOSOMAL RECESSIVE; SPAX4"]
["EIF2AK1","eukaryotic translation initiation factor 2-alpha kinase 1 [Source:HGNC Symbol;Acc:24921]","ENSG00000086232","ENSP00000199389",2,"Pkinase[2]","family-541","EIF2AK1,EIF2AK3,EIF2AK2,EIF2AK4","EIF2AK1","EIF2AK3[25,14],EIF2AK2[19,22],EIF2AK4[27,10]","mRNA","putative mRNA","The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]",".",".",".",".",".",".","GO:0003743,GO:0004694,GO:0006417","translation initiation factor activity,eukaryotic translation initiation factor 2alpha kinase activity,regulation of translation","GO:0005524,GO:0004674,GO:0004672,GO:0004713,GO:0003743,GO:0016772,GO:0006468,GO:0005515,GO:0042803,GO:0042802,GO:0020037,GO:0004694,GO:0005737,GO:0046777,GO:0006417,GO:0046984,GO:0046986,GO:0008285,GO:0006950,GO:0009605,GO:0010999,GO:0046501,GO:0045993","ATP binding,protein serine/threonine kinase activity,protein kinase activity,protein tyrosine kinase activity,translation initiation factor activity,transferase activity, transferring phosphorus-containing groups,protein phosphorylation,protein binding,protein homodimerization activity,identical protein binding,heme binding,eukaryotic translation initiation factor 2alpha kinase activity,cytoplasm,protein autophosphorylation,regulation of translation,regulation of hemoglobin biosynthetic process,negative regulation of hemoglobin biosynthetic process,negative regulation of cell proliferation,response to stress,response to external stimulus,regulation of eIF2 alpha phosphorylation by heme,protoporphyrinogen IX metabolic process,negative regulation of translational initiation by iron","."]
["EIF2AK2","eukaryotic translation initiation factor 2-alpha kinase 2 [Source:HGNC Symbol;Acc:9437]","ENSG00000055332","ENSP00000233057",3,"Pkinase[1],dsrm[2]","family-541","EIF2AK1,EIF2AK3,EIF2AK2,EIF2AK4","EIF2AK1","EIF2AK3[25,14],EIF2AK2[19,22],EIF2AK4[27,10]","ncRNA","viral RNA/ mRNA","The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]","translationfactor",".",".",1,".",".","GO:0003725,GO:0004694,GO:0006412","double-stranded RNA binding,eukaryotic translation initiation factor 2alpha kinase activity,translation","GO:0005515,GO:0005524,GO:0004674,GO:0003725,GO:0004672,GO:0004713,GO:0016772,GO:0008601,GO:0004715,GO:0004694,GO:0005634,GO:0005737,GO:0005829,GO:0048471,GO:0006351,GO:0045087,GO:0008285,GO:0009615,GO:0006412,GO:0045071,GO:0006468,GO:0000186,GO:0046777,GO:0051092,GO:0051607,GO:0017148,GO:0030968,GO:0032874,GO:0032722,GO:0033689,GO:0019048,GO:0019058,GO:0001819,GO:0019054,GO:0035455,GO:0030683,GO:1900225,GO:1901224,GO:1901532,GO:1902033,GO:1902036,GO:0006926","protein binding,ATP binding,protein serine/threonine kinase activity,double-stranded RNA binding,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,protein phosphatase type 2A regulator activity,non-membrane spanning protein tyrosine kinase activity,eukaryotic translation initiation factor 2alpha kinase activity,nucleus,cytoplasm,cytosol,perinuclear region of cytoplasm,transcription, DNA-templated,innate immune response,negative regulation of cell proliferation,response to virus,translation,negative regulation of viral genome replication,protein phosphorylation,activation of MAPKK activity,protein autophosphorylation,positive regulation of NF-kappaB transcription factor activity,defense response to virus,negative regulation of translation,endoplasmic reticulum unfolded protein response,positive regulation of stress-activated MAPK cascade,positive regulation of chemokine production,negative regulation of osteoblast proliferation,modulation by virus of host morphology or physiology,viral life cycle,positive regulation of cytokine production,modulation by virus of host process,response to interferon-alpha,evasion or tolerance by virus of host immune response,regulation of NLRP3 inflammasome complex assembly,positive regulation of NIK/NF-kappaB signaling,regulation of hematopoietic progenitor cell differentiation,regulation of hematopoietic stem cell proliferation,regulation of hematopoietic stem cell differentiation,virus-infected cell apoptotic process","."]
["EIF2AK3","eukaryotic translation initiation factor 2-alpha kinase 3 [Source:HGNC Symbol;Acc:3255]","ENSG00000172071","ENSP00000307235",3,"PQQ_2[1],Pkinase[2]","family-541","EIF2AK1,EIF2AK3,EIF2AK2,EIF2AK4","EIF2AK1","EIF2AK3[25,14],EIF2AK2[19,22],EIF2AK4[27,10]","mRNA","putative mRNA","The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Jan 2010]",".",".",".",".",".",".","GO:0004694,GO:0006412","eukaryotic translation initiation factor 2alpha kinase activity,translation","GO:0005524,GO:0004674,GO:0004672,GO:0004713,GO:0016772,GO:0006468,GO:0005515,GO:0042802,GO:0019903,GO:0004694,GO:0005737,GO:0005783,GO:0005623,GO:0016021,GO:0005789,GO:0001501,GO:0017148,GO:0070059,GO:0006926,GO:0051260,GO:0045444,GO:0006412,GO:0019217,GO:0030282,GO:0032092,GO:0046777,GO:0002063,GO:0031016,GO:0001503,GO:0031018,GO:0044267,GO:0030073,GO:0048009,GO:0030968,GO:0007595,GO:0019722,GO:0034976,GO:0007029,GO:0031642,GO:0032057,GO:0006919,GO:0009967,GO:0032055,GO:0032933,GO:0006983,GO:0006987","ATP binding,protein serine/threonine kinase activity,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,protein phosphorylation,protein binding,identical protein binding,protein phosphatase binding,eukaryotic translation initiation factor 2alpha kinase activity,cytoplasm,endoplasmic reticulum,cell,integral to membrane,endoplasmic reticulum membrane,skeletal system development,negative regulation of translation,intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,virus-infected cell apoptotic process,protein homooligomerization,fat cell differentiation,translation,regulation of fatty acid metabolic process,bone mineralization,positive regulation of protein binding,protein autophosphorylation,chondrocyte development,pancreas development,ossification,endocrine pancreas development,cellular protein metabolic process,insulin secretion,insulin-like growth factor receptor signaling pathway,endoplasmic reticulum unfolded protein response,lactation,calcium-mediated signaling,response to endoplasmic reticulum stress,endoplasmic reticulum organization,negative regulation of myelination,negative regulation of translational initiation in response to stress,activation of cysteine-type endopeptidase activity involved in apoptotic process,positive regulation of signal transduction,negative regulation of translation in response to stress,SREBP signaling pathway,ER overload response,activation of signaling protein activity involved in unfolded protein response"," EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ONSET DIABETES MELLITUS"]
["EIF2AK4","eukaryotic translation initiation factor 2 alpha kinase 4 [Source:HGNC Symbol;Acc:19687]","ENSG00000128829","ENSP00000263791",6,"Pkinase[3],HGTP_anticodon2[1],tRNA-synt_His[1],RWD[1]","family-541","EIF2AK1,EIF2AK3,EIF2AK2,EIF2AK4","EIF2AK1","EIF2AK3[25,14],EIF2AK2[19,22],EIF2AK4[27,10]","tRNA","tRNA","This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014]",".",".",".",".",".",".","GO:0004694,GO:0022626,GO:0006446,GO:0043558","eukaryotic translation initiation factor 2alpha kinase activity,cytosolic ribosome,regulation of translational initiation,regulation of translational initiation in response to stress","GO:0005515,GO:0042803,GO:0005524,GO:0004674,GO:0004672,GO:0004713,GO:0016772,GO:0004694,GO:0005622,GO:0022626,GO:0006468,GO:0006446,GO:0009267,GO:0017148,GO:0030968,GO:0043558","protein binding,protein homodimerization activity,ATP binding,protein serine/threonine kinase activity,protein kinase activity,protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,eukaryotic translation initiation factor 2alpha kinase activity,intracellular,cytosolic ribosome,protein phosphorylation,regulation of translational initiation,cellular response to starvation,negative regulation of translation,endoplasmic reticulum unfolded protein response,regulation of translational initiation in response to stress","."]
["MRPL22","mitochondrial ribosomal protein L22 [Source:HGNC Symbol;Acc:14480]","ENSG00000082515","ENSP00000429039",1,"Ribosomal_L22[1]","family-542","MRPL22",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0015934,GO:0006412","structural constituent of ribosome,ribosome,large ribosomal subunit,translation","GO:0003735,GO:0005840,GO:0015934,GO:0006412,GO:0005739","structural constituent of ribosome,ribosome,large ribosomal subunit,translation,mitochondrion","."]
["PES1","pescadillo ribosomal biogenesis factor 1 [Source:HGNC Symbol;Acc:8848]","ENSG00000100029","ENSP00000384252",2,"BRCT[1],Pescadillo_N[1]","family-543","PES1",".",".","rRNA","rRNA","This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]","candidate mRNA binder","RNArelated",1,1,1,".","GO:0043021,GO:0030687,GO:0042254,GO:0006364,GO:0000463,GO:0000466,GO:0042273","ribonucleoprotein complex binding,preribosome, large subunit precursor,ribosome biogenesis,rRNA processing,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal large subunit biogenesis","GO:0005515,GO:0043021,GO:0005730,GO:0005654,GO:0000793,GO:0030687,GO:0070545,GO:0008283,GO:0042254,GO:0006364,GO:0051726,GO:0033365,GO:0007000,GO:0000463,GO:0000466,GO:0042273,GO:0005694,GO:0005634","protein binding,ribonucleoprotein complex binding,nucleolus,nucleoplasm,condensed chromosome,preribosome, large subunit precursor,PeBoW complex,cell proliferation,ribosome biogenesis,rRNA processing,regulation of cell cycle,protein localization to organelle,nucleolus organization,maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal large subunit biogenesis,chromosome,nucleus","."]
["LSM7","LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:20470]","ENSG00000130332","ENSP00000252622",1,"LSM[1]","family-544","LSM7",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0017070,GO:0005681,GO:0016070,GO:0016071,GO:0000288,GO:0000398,GO:0043928","U6 snRNA binding,spliceosomal complex,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0005515,GO:0017070,GO:0005634,GO:0005829,GO:0005681,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000398,GO:0043928","protein binding,U6 snRNA binding,nucleus,cytosol,spliceosomal complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["PAPD4","PAP associated domain containing 4 [Source:HGNC Symbol;Acc:26776]","ENSG00000164329","ENSP00000397563",2,"PAP_assoc[1],NTP_transf_2[1]","family-545","PAPD4,ZCCHC6,ZCCHC11","PAPD4","ZCCHC6[25,8],ZCCHC11[27,8]","mRNA","mRNA/miRNA",18172165,".",".",".",".",".",".","GO:0031380,GO:0006397,GO:0043631,GO:0071044","nuclear RNA-directed RNA polymerase complex,mRNA processing,RNA polyadenylation,histone mRNA catabolic process","GO:0005524,GO:0046872,GO:0004652,GO:0005737,GO:0031380,GO:0006397,GO:0043631,GO:0071044,GO:0005515,GO:0005634","ATP binding,metal ion binding,polynucleotide adenylyltransferase activity,cytoplasm,nuclear RNA-directed RNA polymerase complex,mRNA processing,RNA polyadenylation,histone mRNA catabolic process,protein binding,nucleus","."]
["ZCCHC11","zinc finger, CCHC domain containing 11 [Source:HGNC Symbol;Acc:28981]","ENSG00000134744","ENSP00000257177",5,"zf-CCHC[2],PAP_assoc[2],NTP_transf_2[1]","family-545","PAPD4,ZCCHC6,ZCCHC11","PAPD4","ZCCHC6[25,8],ZCCHC11[27,8]","ncRNA","miRNA/mRNA",19701194,"RNAbinding","RNArelated",1,1,".",".","GO:0010586,GO:0050265,GO:0031054,GO:0010587,GO:0031123","miRNA metabolic process,RNA uridylyltransferase activity,pre-miRNA processing,miRNA catabolic process,RNA 3'-end processing","GO:0005634,GO:0005737,GO:0032088,GO:0070102,GO:0032755,GO:0010586,GO:0001816,GO:0031664,GO:0008270,GO:0003676,GO:0016779,GO:0005730,GO:0005515,GO:0050265,GO:0019827,GO:0031054,GO:0010587,GO:0031123","nucleus,cytoplasm,negative regulation of NF-kappaB transcription factor activity,interleukin-6-mediated signaling pathway,positive regulation of interleukin-6 production,miRNA metabolic process,cytokine production,regulation of lipopolysaccharide-mediated signaling pathway,zinc ion binding,nucleic acid binding,nucleotidyltransferase activity,nucleolus,protein binding,RNA uridylyltransferase activity,stem cell maintenance,pre-miRNA processing,miRNA catabolic process,RNA 3'-end processing","."]
["ZCCHC6","zinc finger, CCHC domain containing 6 [Source:HGNC Symbol;Acc:25817]","ENSG00000083223","ENSP00000365130",6,"zf-CCHC[3],PAP_assoc[2],NTP_transf_2[1]","family-545","PAPD4,ZCCHC6,ZCCHC11","PAPD4","ZCCHC6[25,8],ZCCHC11[27,8]","ncRNA","miRNA",22898984,"RNAbinding","RNArelated",1,1,".",".","GO:0050265,GO:0031123","RNA uridylyltransferase activity,RNA 3'-end processing","GO:0008270,GO:0003676,GO:0050265,GO:0031123","zinc ion binding,nucleic acid binding,RNA uridylyltransferase activity,RNA 3'-end processing","."]
["KHDRBS1","KH domain containing, RNA binding, signal transduction associated 1 [Source:HGNC Symbol;Acc:18116]","ENSG00000121774","ENSP00000313829",1,"KH_1[1]","family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","KHDRBS1","KHDRBS2[50,63],KHDRBS3[45,57],QKI[23,30],SF1[21,14]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0045948,GO:0046833,GO:0046831","RNA binding,mRNA processing,positive regulation of translational initiation,positive regulation of RNA export from nucleus,regulation of RNA export from nucleus","GO:0003723,GO:0005515,GO:0003677,GO:0032403,GO:0017124,GO:0005070,GO:0005634,GO:0005737,GO:0016020,GO:0070618,GO:0006351,GO:0008283,GO:0045892,GO:0007165,GO:0006397,GO:0007050,GO:0000086,GO:0007166,GO:0045948,GO:0046833,GO:0046831","RNA binding,protein binding,DNA binding,protein complex binding,SH3 domain binding,SH3/SH2 adaptor activity,nucleus,cytoplasm,membrane,Grb2-Sos complex,transcription, DNA-templated,cell proliferation,negative regulation of transcription, DNA-dependent,signal transduction,mRNA processing,cell cycle arrest,G2/M transition of mitotic cell cycle,cell surface receptor signaling pathway,positive regulation of translational initiation,positive regulation of RNA export from nucleus,regulation of RNA export from nucleus","."]
["KHDRBS2","KH domain containing, RNA binding, signal transduction associated 2 [Source:HGNC Symbol;Acc:18114]","ENSG00000112232","ENSP00000281156",1,"KH_1[1]","family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","KHDRBS1","KHDRBS2[50,63],KHDRBS3[45,57],QKI[23,30],SF1[21,14]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0008143,GO:0008266","RNA binding,poly(A) RNA binding,poly(U) RNA binding","GO:0005515,GO:0003723,GO:0042169,GO:0046982,GO:0017124,GO:0008143,GO:0008266,GO:0005634,GO:0006351,GO:0006355","protein binding,RNA binding,SH2 domain binding,protein heterodimerization activity,SH3 domain binding,poly(A) RNA binding,poly(U) RNA binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["KHDRBS3","KH domain containing, RNA binding, signal transduction associated 3 [Source:HGNC Symbol;Acc:18117]","ENSG00000131773","ENSP00000431022",1,"KH_1[1]","family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","KHDRBS1","KHDRBS2[50,63],KHDRBS3[45,57],QKI[23,30],SF1[21,14]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005634,GO:0005515,GO:0017124,GO:0006351,GO:0007283,GO:0006355","RNA binding,nucleus,protein binding,SH3 domain binding,transcription, DNA-templated,spermatogenesis,regulation of transcription, DNA-dependent","."]
["QKI","QKI, KH domain containing, RNA binding [Source:HGNC Symbol;Acc:21100]","ENSG00000112531","ENSP00000275262",1,"KH_1[1]","family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","KHDRBS1","KHDRBS2[50,63],KHDRBS3[45,57],QKI[23,30],SF1[21,14]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0006417,GO:0006397,GO:0008380,GO:0051028","RNA binding,regulation of translation,mRNA processing,RNA splicing,mRNA transport","GO:0003723,GO:0010628,GO:0007286,GO:0042552,GO:0042759,GO:0001570,GO:0042692,GO:0005515,GO:0017124,GO:0005634,GO:0005737,GO:0006417,GO:0006397,GO:0008380,GO:0051028,GO:0008366","RNA binding,positive regulation of gene expression,spermatid development,myelination,long-chain fatty acid biosynthetic process,vasculogenesis,muscle cell differentiation,protein binding,SH3 domain binding,nucleus,cytoplasm,regulation of translation,mRNA processing,RNA splicing,mRNA transport,axon ensheathment","."]
["SF1","splicing factor 1 [Source:HGNC Symbol;Acc:12950]","ENSG00000168066","ENSP00000396793",2,"zf-CCHC[1],KH_1[1]","family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","KHDRBS1","KHDRBS2[50,63],KHDRBS3[45,57],QKI[23,30],SF1[21,14]","mRNA","mRNA","This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence and is required for the early stages of spliceosome assembly. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005840,GO:0005681,GO:0000398,GO:0000245,GO:0000389","RNA binding,ribosome,spliceosomal complex,mRNA splicing, via spliceosome,spliceosomal complex assembly,mRNA 3'-splice site recognition","GO:0003723,GO:0008270,GO:0003676,GO:0050810,GO:0022402,GO:0030238,GO:0033327,GO:0003714,GO:0005634,GO:0005840,GO:0005681,GO:0006351,GO:0006355,GO:0000398,GO:0000245,GO:0000389,GO:0048662","RNA binding,zinc ion binding,nucleic acid binding,regulation of steroid biosynthetic process,cell cycle process,male sex determination,Leydig cell differentiation,transcription corepressor activity,nucleus,ribosome,spliceosomal complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,mRNA splicing, via spliceosome,spliceosomal complex assembly,mRNA 3'-splice site recognition,negative regulation of smooth muscle cell proliferation","."]
["LRRC47","leucine rich repeat containing 47 [Source:HGNC Symbol;Acc:29207]","ENSG00000130764","ENSP00000367498",4,"LRR_4[3],B3_4[1]","family-547","LRRC47",".",".","unknown","unknown","established RBP ","RNAbinding",".",".",1,1,".","GO:0003723,GO:0004826","RNA binding,phenylalanine-tRNA ligase activity","GO:0003723,GO:0005515,GO:0004826","RNA binding,protein binding,phenylalanine-tRNA ligase activity","."]
["ISY1","ISY1 splicing factor homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29201]","ENSG00000240682","ENSP00000376973",1,"Isy1[1]","family-548","ISY1",".",".","mRNA","mRNA","established RBP ",".","RNArelated",".",1,1,".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0005634,GO:0071013,GO:0000398","protein binding,nucleus,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["SRRM1","serine/arginine repetitive matrix 1 [Source:HGNC Symbol;Acc:16638]","ENSG00000133226","ENSP00000469151",1,"PWI[1]","family-549","SRRM1",".",".","mRNA","mRNA",16159877,"RNAbinding",".",".",1,1,1,"GO:0006397,GO:0005681,GO:0003723,GO:0071013,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0000375","mRNA processing,spliceosomal complex,RNA binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,RNA splicing, via transesterification reactions","GO:0006397,GO:0005681,GO:0003723,GO:0003677,GO:0005634,GO:0005829,GO:0005654,GO:0016363,GO:0016607,GO:0071013,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0000375,GO:0006369","mRNA processing,spliceosomal complex,RNA binding,DNA binding,nucleus,cytosol,nucleoplasm,nuclear matrix,nuclear speck,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,RNA splicing, via transesterification reactions,termination of RNA polymerase II transcription","."]
["IPO9","importin 9 [Source:HGNC Symbol;Acc:19425]","ENSG00000198700","ENSP00000354742",2,"IBN_N[1],Xpo1[1]","family-55","IPO9",".",".","mRNA","putative mRBP transport",23851686,".",".",".",".",".",".",".",".","GO:0005488,GO:0042393,GO:0005515,GO:0008565,GO:0008536,GO:0005634,GO:0005737,GO:0006606,GO:0006886","binding,histone binding,protein binding,protein transporter activity,Ran GTPase binding,nucleus,cytoplasm,protein import into nucleus,intracellular protein transport","."]
["MTRF1","mitochondrial translational release factor 1 [Source:HGNC Symbol;Acc:7469]","ENSG00000120662","ENSP00000400031",2,"PCRF[1],RF-1[1]","family-550","MTRF1,MTRF1L","MTRF1","MTRF1L[36,42]","mRNA","mRNA",17803939,".",".",".",".",".",".","GO:0016149,GO:0003747,GO:0006415,GO:0006449","translation release factor activity, codon specific,translation release factor activity,translational termination,regulation of translational termination","GO:0016149,GO:0003747,GO:0005737,GO:0006415,GO:0005739,GO:0006449","translation release factor activity, codon specific,translation release factor activity,cytoplasm,translational termination,mitochondrion,regulation of translational termination","."]
["MTRF1L","mitochondrial translational release factor 1-like [Source:HGNC Symbol;Acc:21051]","ENSG00000112031","ENSP00000356202",2,"PCRF[1],RF-1[1]","family-550","MTRF1,MTRF1L","MTRF1","MTRF1L[36,42]","mRNA","mRNA","MTRF1L is a nuclear-encoded protein that functions as a releasing factor that recognizes termination codons and releases mitochondrial ribosomes from the synthesized protein (summary by Nozaki et al., 2008 [PubMed 18429816]).[supplied by OMIM, Nov 2010]",".",".",".",".",".",".","GO:0003747,GO:0006415,GO:0016149","translation release factor activity,translational termination,translation release factor activity, codon specific","GO:0003747,GO:0006415,GO:0016149,GO:0005737,GO:0005739","translation release factor activity,translational termination,translation release factor activity, codon specific,cytoplasm,mitochondrion","."]
["WIBG","within bgcn homolog (Drosophila) [Source:HGNC Symbol;Acc:30258]","ENSG00000170473","ENSP00000381271",1,"Mago-bind[1]","family-551","WIBG",".",".","mRNA","mRNA",18026120,"RNAbinding",".",".",1,1,".","GO:0003723,GO:0043022,GO:0045727,GO:0000184","RNA binding,ribosome binding,positive regulation of translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0003723,GO:0005515,GO:0043022,GO:0005737,GO:0005730,GO:0005654,GO:0035145,GO:0045727,GO:0000184","RNA binding,protein binding,ribosome binding,cytoplasm,nucleolus,nucleoplasm,exon-exon junction complex,positive regulation of translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["PPAN","peter pan homolog (Drosophila) [Source:HGNC Symbol;Acc:9227]","ENSG00000130810","ENSP00000450710",2,"7tm_1[1],Brix[1]","family-552","PPAN",".",".","mRNA","mRNA","The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010]","candidate mRNA binder","RNArelated",1,1,1,".","GO:0008380","RNA splicing","GO:0004930,GO:0016021,GO:0005634,GO:0005737,GO:0007186,GO:0008380","G-protein coupled receptor activity,integral to membrane,nucleus,cytoplasm,G-protein coupled receptor signaling pathway,RNA splicing","."]
["FUBP3","far upstream element (FUSE) binding protein 3 [Source:HGNC Symbol;Acc:4005]","ENSG00000107164","ENSP00000318177",4,"KH_1[4]","family-553","FUBP1,KHSRP,FUBP3","FUBP1","KHSRP[65,59],FUBP3[52,58]","mRNA","mRNA",21252297,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0003677,GO:0005634,GO:0005737,GO:0006351,GO:0045893,GO:0010628","RNA binding,DNA binding,nucleus,cytoplasm,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,positive regulation of gene expression","."]
["FUBP1","far upstream element (FUSE) binding protein 1 [Source:HGNC Symbol;Acc:4004]","ENSG00000162613","ENSP00000389536",6,"DUF1897[2],KH_1[4]","family-553","FUBP1,KHSRP,FUBP3","FUBP1","KHSRP[65,59],FUBP3[52,58]","mRNA","mRNA",21855647,"helicase","experimentally validated",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0005634,GO:0005515,GO:0003700,GO:0003697,GO:0006366,GO:0010628","RNA binding,nucleus,protein binding,sequence-specific DNA binding transcription factor activity,single-stranded DNA binding,transcription from RNA polymerase II promoter,positive regulation of gene expression","."]
["KHSRP","KH-type splicing regulatory protein [Source:HGNC Symbol;Acc:6316]","ENSG00000088247","ENSP00000381216",6,"DUF1897[2],KH_1[4]","family-553","FUBP1,KHSRP,FUBP3","FUBP1","KHSRP[65,59],FUBP3[52,58]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0010494,GO:0016070,GO:0016071,GO:0006397,GO:0008380,GO:0051028,GO:0000375","RNA binding,cytoplasmic stress granule,RNA metabolic process,mRNA metabolic process,mRNA processing,RNA splicing,mRNA transport,RNA splicing, via transesterification reactions","GO:0003723,GO:0010494,GO:0003677,GO:0005634,GO:0005829,GO:0005654,GO:0006351,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0006397,GO:0008380,GO:0051028,GO:0000375","RNA binding,cytoplasmic stress granule,DNA binding,nucleus,cytosol,nucleoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,mRNA processing,RNA splicing,mRNA transport,RNA splicing, via transesterification reactions","."]
["CHTOP","chromatin target of PRMT1 [Source:HGNC Symbol;Acc:24511] [Type: protein coding Ensembl/Havana merge]","ENSG00000160679","ENSP00000357683",1,"FoP_duplication[1]","family-554","CHTOP",".",".","mRNA","mRNA",23299939,"RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0006406","RNA binding,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0005634,GO:0043231,GO:0016607,GO:0000346,GO:0006351,GO:0006355,GO:0006406,GO:0032781,GO:0051096","RNA binding,protein binding,nucleus,intracellular membrane-bounded organelle,nuclear speck,transcription export complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,mRNA export from nucleus,positive regulation of ATPase activity,positive regulation of helicase activity","."]
["PTCD2","pentatricopeptide repeat domain 2 [Source:HGNC Symbol;Acc:25734]","ENSG00000049883","ENSP00000370013",1,"MRP-S27[1]","family-555","PTCD2",".",".","mRNA","putative mRNA",18729827,"candidate mRNA binder","RNArelated",1,1,1,".","GO:0050684,GO:0006397","regulation of mRNA processing,mRNA processing","GO:0005739,GO:0001889,GO:0007005,GO:0055010,GO:0001822,GO:0050684,GO:0048747,GO:0006397,GO:0010468,GO:0007507","mitochondrion,liver development,mitochondrion organization,ventricular cardiac muscle tissue morphogenesis,kidney development,regulation of mRNA processing,muscle fiber development,mRNA processing,regulation of gene expression,heart development","."]
["POLR2A","polymerase (RNA) II (DNA directed) polypeptide A, 220kDa [Source:HGNC Symbol;Acc:9187]","ENSG00000181222","ENSP00000314949",6,"RNA_pol_Rpb1_3[1],RNA_pol_Rpb1_R[1],RNA_pol_Rpb1_2[1],RNA_pol_Rpb1_1[1],RNA_pol_Rpb1_5[1],RNA_pol_Rpb1_4[1]","family-556","POLR2A,POLR3A","POLR2A","POLR3A[25,35]","mRNA","mRNA","This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]","candidate mRNA binder","RNArelated",1,1,".",".","GO:0003968,GO:0008380,GO:0000398,GO:0006370","RNA-directed RNA polymerase activity,RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003899,GO:0006351,GO:0005515,GO:0046872,GO:0031625,GO:0001055,GO:0003968,GO:0005634,GO:0005654,GO:0005665,GO:0006366,GO:0006289,GO:0006355,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","DNA binding,DNA-directed RNA polymerase activity,transcription, DNA-templated,protein binding,metal ion binding,ubiquitin protein ligase binding,RNA polymerase II activity,RNA-directed RNA polymerase activity,nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter,nucleotide-excision repair,regulation of transcription, DNA-dependent,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["MRPL43","mitochondrial ribosomal protein L43 [Source:HGNC Symbol;Acc:14517]","ENSG00000055950","ENSP00000359256",1,"L51_S25_CI-B8[1]","family-557","MRPL43",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0005840,GO:0003735,GO:0005761,GO:0006412","ribosome,structural constituent of ribosome,mitochondrial ribosome,translation","GO:0005739,GO:0005840,GO:0003735,GO:0005761,GO:0006412","mitochondrion,ribosome,structural constituent of ribosome,mitochondrial ribosome,translation","."]
["DDX55","DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Source:HGNC Symbol;Acc:20085]","ENSG00000111364","ENSP00000238146",3,"DUF4217[1],Helicase_C[1],DEAD[1]","family-558","DDX55",".",".","rRNA","rRNA","SPB4 yeast homolog",".","RNAbinding",".",1,".",".","GO:0003723","RNA binding","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0003723,GO:0004386","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,RNA binding,helicase activity","."]
["RPS15","ribosomal protein S15 [Source:HGNC Symbol;Acc:10388]","ENSG00000115268","ENSP00000465055",1,"Ribosomal_S19[1]","family-559","RPS15",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0015935,GO:0022627,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274,GO:0000056","structural constituent of ribosome,ribosome,translation,RNA binding,small ribosomal subunit,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis,ribosomal small subunit export from nucleus","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0015935,GO:0003677,GO:0005634,GO:0005829,GO:0022627,GO:0005654,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274,GO:0000056","structural constituent of ribosome,ribosome,translation,RNA binding,small ribosomal subunit,DNA binding,nucleus,cytosol,cytosolic small ribosomal subunit,nucleoplasm,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis,ribosomal small subunit export from nucleus","."]
["CPSF4","cleavage and polyadenylation specific factor 4, 30kDa [Source:HGNC Symbol;Acc:2327]","ENSG00000160917","ENSP00000402224",4,"zf-CCHC[1],zf-CCCH[3]","family-56","CPSF4,CPSF4L","CPSF4","CPSF4L[42,63]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0005847,GO:0006397,GO:0046778","RNA binding,mRNA cleavage and polyadenylation specificity factor complex,mRNA processing,modification by virus of host mRNA processing","GO:0046872,GO:0008270,GO:0003676,GO:0003723,GO:0005634,GO:0005739,GO:0005654,GO:0005847,GO:0006397,GO:0019048,GO:0019058,GO:0019054,GO:0046778","metal ion binding,zinc ion binding,nucleic acid binding,RNA binding,nucleus,mitochondrion,nucleoplasm,mRNA cleavage and polyadenylation specificity factor complex,mRNA processing,modulation by virus of host morphology or physiology,viral life cycle,modulation by virus of host process,modification by virus of host mRNA processing","."]
["CPSF4L","cleavage and polyadenylation specific factor 4-like [Source:HGNC Symbol;Acc:33632]","ENSG00000187959","ENSP00000380788",3,"zf-CCCH[3]","family-56","CPSF4,CPSF4L","CPSF4","CPSF4L[42,63]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0046872,GO:0003723","metal ion binding,RNA binding","."]
["CSTF2","cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa [Source:HGNC Symbol;Acc:2484]","ENSG00000101811","ENSP00000387996",3,"RRM_1[1],CSTF2_hinge[1],CSTF_C[1]","family-560","CSTF2,CSTF2T","CSTF2","CSTF2T[74,69]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005847,GO:0008380,GO:0000398,GO:0006379,GO:0031124,GO:0006378","RNA binding,mRNA cleavage and polyadenylation specificity factor complex,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation","GO:0000166,GO:0003676,GO:0005634,GO:0003723,GO:0005515,GO:0005654,GO:0005847,GO:0071920,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006379,GO:0031124,GO:0006378,GO:0006369","nucleotide binding,nucleic acid binding,nucleus,RNA binding,protein binding,nucleoplasm,mRNA cleavage and polyadenylation specificity factor complex,cleavage body,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription","."]
["CSTF2T","cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant [Source:HGNC Symbol;Acc:17086]","ENSG00000177613","ENSP00000332444",3,"RRM_1[1],CSTF2_hinge[1],CSTF_C[1]","family-560","CSTF2,CSTF2T","CSTF2","CSTF2T[74,69]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005622,GO:0006397","nucleotide binding,RNA binding,nucleic acid binding,nucleus,intracellular,mRNA processing","."]
["RAVER2","ribonucleoprotein, PTB-binding 2 [Source:HGNC Symbol;Acc:25577]","ENSG00000162437","ENSP00000294428",3,"RRM_1[2],RRM_6[1]","family-561","RAVER1,RAVER2","RAVER1","RAVER2[41,37]","mRNA","mRNA",16051233,"RNAbinding","RNAbinding",1,1,".",1,"GO:0030529,GO:0003723","ribonucleoprotein complex,RNA binding","GO:0030529,GO:0019013,GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005737,GO:0005515","ribonucleoprotein complex,viral nucleocapsid,nucleotide binding,RNA binding,nucleic acid binding,nucleus,cytoplasm,protein binding","."]
["RAVER1","ribonucleoprotein, PTB-binding 1 [Source:HGNC Symbol;Acc:30296]","ENSG00000161847","ENSP00000293677",3,"RRM_1[1],RRM_6[2]","family-561","RAVER1,RAVER2","RAVER1","RAVER2[41,37]","mRNA","mRNA",19523901,"RNAbinding","RNAbinding",1,1,1,1,".",".","GO:0000166,GO:0003676","nucleotide binding,nucleic acid binding","."]
["EIF1AX","eukaryotic translation initiation factor 1A, X-linked [Source:HGNC Symbol;Acc:3250]","ENSG00000173674","ENSP00000368927",1,"eIF-1a[1]","family-562","EIF1AX,EIF1AY","EIF1AX","EIF1AY[99,99]","mRNA","putative mRNA",10678173,"translationfactor","RNAbinding",1,1,1,".","GO:0003723,GO:0003743,GO:0006413,GO:0008135,GO:0006412","RNA binding,translation initiation factor activity,translational initiation,translation factor activity, nucleic acid binding,translation","GO:0003723,GO:0003743,GO:0006413,GO:0008135,GO:0005829,GO:0006412,GO:0010467,GO:0044267","RNA binding,translation initiation factor activity,translational initiation,translation factor activity, nucleic acid binding,cytosol,translation,gene expression,cellular protein metabolic process","."]
["EIF1AY","eukaryotic translation initiation factor 1A, Y-linked [Source:HGNC Symbol;Acc:3252]","ENSG00000198692","ENSP00000354722",1,"eIF-1a[1]","family-562","EIF1AX,EIF1AY","EIF1AX","EIF1AY[99,99]","mRNA","putative mRNA",10678173,".",".",".",".",1,".","GO:0003723,GO:0003743,GO:0006413","RNA binding,translation initiation factor activity,translational initiation","GO:0003723,GO:0003743,GO:0006413,GO:0005515","RNA binding,translation initiation factor activity,translational initiation,protein binding","."]
["DALRD3","DALR anticodon binding domain containing 3 [Source:HGNC Symbol;Acc:25536]","ENSG00000178149","ENSP00000396650",1,"DALR_1[1]","family-563","DALRD3",".",".","tRNA","putative tRNA","The exact function of this gene is not known. It encodes a protein with a DALR anticodon binding domain similar to that of class Ia aminoacyl tRNA synthetases. This gene is located in a cluster of genes (with a complex sense-anti-sense genome architecture) on chromosome 3, and contains two micro RNA (miRNA) precursors (mir-425 and mir-191) in one of its introns. Preferential expression of this gene (the miRNAs and other genes in the cluster) in testis suggests a role of this gene in spermatogenesis (PMID:19906709). [provided by RefSeq, Feb 2013]",".",".",".",".",".",".","GO:0004812,GO:0004814,GO:0006418,GO:0006420","aminoacyl-tRNA ligase activity,arginine-tRNA ligase activity,tRNA aminoacylation for protein translation,arginyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004814,GO:0006418,GO:0006420","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,arginine-tRNA ligase activity,tRNA aminoacylation for protein translation,arginyl-tRNA aminoacylation","."]
["NSUN2","NOP2/Sun RNA methyltransferase family, member 2 [Source:HGNC Symbol;Acc:25994]","ENSG00000037474","ENSP00000420957",1,"Nol1_Nop2_Fmu[1]","family-564","NSUN2",".",".","tRNA","tRNA/vtRNA","This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Mar 2011]","RNAmod","RNAbinding",1,1,1,".","GO:0016428,GO:0000049,GO:0030488","tRNA (cytosine-5-)-methyltransferase activity,tRNA binding,tRNA methylation","GO:0016428,GO:0005634,GO:0000049,GO:0005737,GO:0005730,GO:0005819,GO:0007067,GO:0030488","tRNA (cytosine-5-)-methyltransferase activity,nucleus,tRNA binding,cytoplasm,nucleolus,spindle,mitosis,tRNA methylation"," MENTAL RETARDATION, AUTOSOMAL RECESSIVE 5; MRT5"]
["URB2","URB2 ribosome biogenesis 2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28967]","ENSG00000135763","ENSP00000258243",1,"Urb2[1]","family-565","URB2",".",".","rRNA","rRNA","by homology",".",".",".",".",1,".",".",".","GO:0005634,GO:0005730","nucleus,nucleolus","."]
["PHAX","phosphorylated adaptor for RNA export [Source:HGNC Symbol;Acc:10241]","ENSG00000164902","ENSP00000297540",1,"RNA_GG_bind[1]","family-566","PHAX",".",".","snRNA","snRNA/snoRNA",20430857,".",".",".",".",".",".","GO:0003723,GO:0006408,GO:0016070,GO:0000387,GO:0034660","RNA binding,snRNA export from nucleus,RNA metabolic process,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0003723,GO:0015643,GO:0005737,GO:0005634,GO:0005829,GO:0005654,GO:0043025,GO:0015030,GO:0006408,GO:0015031,GO:0010467,GO:0016070,GO:0000387,GO:0034660","RNA binding,toxic substance binding,cytoplasm,nucleus,cytosol,nucleoplasm,neuronal cell body,Cajal body,snRNA export from nucleus,protein transport,gene expression,RNA metabolic process,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["PPARGC1A","peroxisome proliferator-activated receptor gamma, coactivator 1 alpha [Source:HGNC Symbol;Acc:9237]","ENSG00000109819","ENSP00000264867",1,"RRM_1[1]","family-567","PPARGC1A,PPARGC1B,PPRC1","PPARGC1A","PPARGC1B[30,24],PPRC1[25,12]","unknown","unknown","by domain",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0001104,GO:0003677,GO:0008134,GO:0003713,GO:0031490,GO:0016922,GO:0050681,GO:0030374,GO:0005634,GO:0005829,GO:0016605,GO:0005654,GO:0005665,GO:0045944,GO:0045893,GO:0007586,GO:0001666,GO:0006397,GO:0008380,GO:0006367,GO:0006461,GO:2000310,GO:0010941,GO:0050873,GO:0046321,GO:0043524,GO:0007005,GO:0042594,GO:0070997,GO:0051091,GO:0022904,GO:0001659,GO:0006094,GO:0030521,GO:0034599,GO:0035066,GO:0050821,GO:0019395,GO:0001678,GO:0014850,GO:0045722,GO:0045333,GO:2001171,GO:0010822,GO:2000507,GO:1901857,GO:1901860,GO:1901863,GO:0003682,GO:0003676,GO:0042493,GO:0014823,GO:0014070,GO:0071456,GO:0071250,GO:0031325,GO:0051552,GO:0071871,GO:2000272,GO:0071873,GO:0043201,GO:0036273,GO:0045820,GO:0006012,GO:0008209,GO:0097067,GO:0031667,GO:0071398,GO:0009409,GO:0071356,GO:0048661","nucleotide binding,RNA binding,protein binding,RNA polymerase II transcription cofactor activity,DNA binding,transcription factor binding,transcription coactivator activity,chromatin DNA binding,ligand-dependent nuclear receptor binding,androgen receptor binding,ligand-dependent nuclear receptor transcription coactivator activity,nucleus,cytosol,PML body,nucleoplasm,DNA-directed RNA polymerase II, core complex,positive regulation of transcription from RNA polymerase II promoter,positive regulation of transcription, DNA-dependent,digestion,response to hypoxia,mRNA processing,RNA splicing,transcription initiation from RNA polymerase II promoter,protein complex assembly,regulation of N-methyl-D-aspartate selective glutamate receptor activity,regulation of cell death,brown fat cell differentiation,positive regulation of fatty acid oxidation,negative regulation of neuron apoptotic process,mitochondrion organization,response to starvation,neuron death,positive regulation of sequence-specific DNA binding transcription factor activity,respiratory electron transport chain,temperature homeostasis,gluconeogenesis,androgen receptor signaling pathway,cellular response to oxidative stress,positive regulation of histone acetylation,protein stabilization,fatty acid oxidation,cellular glucose homeostasis,response to muscle activity,positive regulation of gluconeogenesis,cellular respiration,positive regulation of ATP biosynthetic process,positive regulation of mitochondrion organization,positive regulation of energy homeostasis,positive regulation of cellular respiration,positive regulation of mitochondrial DNA metabolic process,positive regulation of muscle tissue development,chromatin binding,nucleic acid binding,response to drug,response to activity,response to organic cyclic compound,cellular response to hypoxia,cellular response to nitrite,positive regulation of cellular metabolic process,flavone metabolic process,response to epinephrine,negative regulation of receptor activity,response to norepinephrine,response to leucine,response to statin,negative regulation of glycolysis,galactose metabolic process,androgen metabolic process,cellular response to thyroid hormone stimulus,response to nutrient levels,cellular response to fatty acid,response to cold,cellular response to tumor necrosis factor,positive regulation of smooth muscle cell proliferation","."]
["PPARGC1B","peroxisome proliferator-activated receptor gamma, coactivator 1 beta [Source:HGNC Symbol;Acc:30022]","ENSG00000155846","ENSP00000312649",1,"RRM_1[1]","family-567","PPARGC1A,PPARGC1B,PPRC1","PPARGC1A","PPARGC1B[30,24],PPRC1[25,12]","unknown","unknown","by domain",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003676,GO:0000166,GO:0003723,GO:0001104,GO:0030331,GO:0030374,GO:0030546,GO:0050682,GO:0005634,GO:0016592,GO:0005654,GO:0045944,GO:0044255,GO:0044281,GO:0045892,GO:0007015,GO:0051591,GO:0051384,GO:0006390,GO:0001503,GO:0034614,GO:0060346,GO:0010694,GO:0045672,GO:0045780,GO:0030520,GO:0042327,GO:2000273,GO:0005515,GO:0045893","nucleic acid binding,nucleotide binding,RNA binding,RNA polymerase II transcription cofactor activity,estrogen receptor binding,ligand-dependent nuclear receptor transcription coactivator activity,receptor activator activity,AF-2 domain binding,nucleus,mediator complex,nucleoplasm,positive regulation of transcription from RNA polymerase II promoter,cellular lipid metabolic process,small molecule metabolic process,negative regulation of transcription, DNA-dependent,actin filament organization,response to cAMP,response to glucocorticoid,transcription from mitochondrial promoter,ossification,cellular response to reactive oxygen species,bone trabecula formation,positive regulation of alkaline phosphatase activity,positive regulation of osteoclast differentiation,positive regulation of bone resorption,intracellular estrogen receptor signaling pathway,positive regulation of phosphorylation,positive regulation of receptor activity,protein binding,positive regulation of transcription, DNA-dependent","."]
["PPRC1","peroxisome proliferator-activated receptor gamma, coactivator-related 1 [Source:HGNC Symbol;Acc:30025]","ENSG00000148840","ENSP00000359029",1,"RRM_1[1]","family-567","PPARGC1A,PPARGC1B,PPRC1","PPARGC1A","PPARGC1B[30,24],PPRC1[25,12]","mRNA","putative mRNA","by homology",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0005634,GO:0003723,GO:0006351,GO:0006355","nucleotide binding,nucleic acid binding,nucleus,RNA binding,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["PHF5A","PHD finger protein 5A [Source:HGNC Symbol;Acc:18000]","ENSG00000100410","ENSP00000216252",1,"PHF5[1]","family-568","PHF5A",".",".","mRNA","mRNA/snRNA","This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,".",".","GO:0005686,GO:0005689,GO:0008380,GO:0000398","U2 snRNP,U12-type spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome","GO:0005515,GO:0003700,GO:0003677,GO:0016607,GO:0005654,GO:0016363,GO:0005686,GO:0005689,GO:0045893,GO:0006351,GO:0010467,GO:0008380,GO:0000398","protein binding,sequence-specific DNA binding transcription factor activity,DNA binding,nuclear speck,nucleoplasm,nuclear matrix,U2 snRNP,U12-type spliceosomal complex,positive regulation of transcription, DNA-dependent,transcription, DNA-templated,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["MCTS1","malignant T cell amplified sequence 1 [Source:HGNC Symbol;Acc:23357]","ENSG00000232119","ENSP00000360367",1,"PUA[1]","family-569","MCTS1",".",".","unknown","unknown","by domain",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005737,GO:0006351,GO:0006974,GO:0006355,GO:0008284,GO:0007049,GO:0040008","RNA binding,cytoplasm,transcription, DNA-templated,cellular response to DNA damage stimulus,regulation of transcription, DNA-dependent,positive regulation of cell proliferation,cell cycle,regulation of growth","."]
["RRP7A","ribosomal RNA processing 7 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:24286]","ENSG00000189306","ENSP00000321449",2,"RRP7[1],RRM_1[1]","family-57","RRP7A",".",".","rRNA","rRNA","Essential protein involved in rRNA processing and ribosome biogenesis; protein abundance increases in response to DNA replication stress",".","RNAbinding",".",1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723","nucleotide binding,RNA binding","."]
["DGCR8","DiGeorge syndrome critical region gene 8 [Source:HGNC Symbol;Acc:2847]","ENSG00000128191","ENSP00000263209",3,"WW[1],dsrm[2]","family-570","DGCR8",".",".","ncRNA","miRNA","established RBP ",".",".",".",".",".",".","GO:0003725,GO:0031053","double-stranded RNA binding,primary miRNA processing","GO:0005515,GO:0046872,GO:0003725,GO:0005634,GO:0005737,GO:0005654,GO:0015630,GO:0010467,GO:0031053","protein binding,metal ion binding,double-stranded RNA binding,nucleus,cytoplasm,nucleoplasm,microtubule cytoskeleton,gene expression,primary miRNA processing","."]
["ZC3H13","zinc finger CCCH-type containing 13 [Source:HGNC Symbol;Acc:20368]","ENSG00000123200","ENSP00000282007",2,"DUF1777[1],zf-CCCH[1]","family-571","ZC3H13",".",".","unknown","unknown","by homology","RNAbinding",".",".",1,".",1,".",".","GO:0046872,GO:0005515","metal ion binding,protein binding","."]
["UPF3A","UPF3 regulator of nonsense transcripts homolog A (yeast) [Source:HGNC Symbol;Acc:20332]","ENSG00000169062","ENSP00000364448",1,"Smg4_UPF3[1]","family-572","UPF3A,UPF3B","UPF3A","UPF3B[43,43]","mRNA","mRNA","This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0016070,GO:0016071,GO:0051028,GO:0045727,GO:0000184","RNA binding,RNA metabolic process,mRNA metabolic process,mRNA transport,positive regulation of translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0000166,GO:0003723,GO:0005515,GO:0005487,GO:0005634,GO:0005886,GO:0005737,GO:0005829,GO:0035145,GO:0010467,GO:0016070,GO:0016071,GO:0051028,GO:0045727,GO:0006913,GO:0000184","nucleotide binding,RNA binding,protein binding,nucleocytoplasmic transporter activity,nucleus,plasma membrane,cytoplasm,cytosol,exon-exon junction complex,gene expression,RNA metabolic process,mRNA metabolic process,mRNA transport,positive regulation of translation,nucleocytoplasmic transport,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["UPF3B","UPF3 regulator of nonsense transcripts homolog B (yeast) [Source:HGNC Symbol;Acc:20439]","ENSG00000125351","ENSP00000245418",1,"Smg4_UPF3[1]","family-572","UPF3A,UPF3B","UPF3A","UPF3B[43,43]","mRNA","mRNA","This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,".",1,"GO:0003729,GO:0016070,GO:0016071,GO:0008380,GO:0000398,GO:0045727,GO:0006406,GO:0031124,GO:0000184","mRNA binding,RNA metabolic process,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,positive regulation of translation,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0000166,GO:0005515,GO:0003729,GO:0005487,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0035145,GO:0006366,GO:0010467,GO:0016070,GO:0016071,GO:0008380,GO:0000398,GO:0045727,GO:0006406,GO:0031124,GO:0000184,GO:0006369","nucleotide binding,protein binding,mRNA binding,nucleocytoplasmic transporter activity,nucleus,cytoplasm,cytosol,nucleoplasm,exon-exon junction complex,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,positive regulation of translation,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription"," MENTAL RETARDATION, X-LINKED, SYNDROMIC 14; MRXS14"]
["RBM24","RNA binding motif protein 24 [Source:HGNC Symbol;Acc:21539]","ENSG00000112183","ENSP00000426222",1,"RRM_6[1]","family-573","RBM24,RBM38","RBM24","RBM38[68,67]","mRNA","mRNA",24356969,".",".",".",".",".",1,"GO:0003730,GO:0043488","mRNA 3'-UTR binding,regulation of mRNA stability","GO:0000166,GO:0003730,GO:0005634,GO:0005737,GO:0030154,GO:0010830,GO:0043488,GO:0003676","nucleotide binding,mRNA 3'-UTR binding,nucleus,cytoplasm,cell differentiation,regulation of myotube differentiation,regulation of mRNA stability,nucleic acid binding","."]
["RBM38","RNA binding motif protein 38 [Source:HGNC Symbol;Acc:15818]","ENSG00000132819","ENSP00000407848",1,"RRM_1[1]","family-573","RBM24,RBM38","RBM24","RBM38[68,67]","mRNA","mRNA","24375645, 19817877","RNAbinding","experimentally validated",1,1,1,1,"GO:0003729,GO:0003730,GO:0006397,GO:0008380,GO:0043484,GO:0070935","mRNA binding,mRNA 3'-UTR binding,mRNA processing,RNA splicing,regulation of RNA splicing,3'-UTR-mediated mRNA stabilization","GO:0003729,GO:0010830,GO:0000166,GO:0003676,GO:0003730,GO:0005634,GO:0005829,GO:0030154,GO:0008285,GO:0006977,GO:0007049,GO:0006397,GO:0008380,GO:0007050,GO:0043484,GO:0006978,GO:0070935","mRNA binding,regulation of myotube differentiation,nucleotide binding,nucleic acid binding,mRNA 3'-UTR binding,nucleus,cytosol,cell differentiation,negative regulation of cell proliferation,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,cell cycle,mRNA processing,RNA splicing,cell cycle arrest,regulation of RNA splicing,DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,3'-UTR-mediated mRNA stabilization","."]
["THOC3","THO complex 3 [Source:HGNC Symbol;Acc:19072]","ENSG00000051596","ENSP00000265097",4,"WD40[4]","family-574","THOC3",".",".","mRNA","mRNA","This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, May 2013]",".",".",".",".",".",".","GO:0003723,GO:0000445,GO:0006397,GO:0008380,GO:0006406","RNA binding,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus","GO:0005515,GO:0003723,GO:0016607,GO:0000346,GO:0000445,GO:0006397,GO:0008380,GO:0006406,GO:0046784","protein binding,RNA binding,nuclear speck,transcription export complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus,viral mRNA export from host cell nucleus","."]
["IGHMBP2","immunoglobulin mu binding protein 2 [Source:HGNC Symbol;Acc:5542]","ENSG00000132740","ENSP00000255078",4,"R3H[1],AAA_11[1],zf-AN1[1],AAA_12[1]","family-575","IGHMBP2",".",".","tRNA","tRNA","19299493, IGHMBP2 associates physically with tRNAs and in particular with tRNA(Tyr), which are present in the modifier and with the ABT1 protein.",".",".",".",".",".",".","GO:0003723,GO:0000049,GO:0043022,GO:0008186,GO:0032575,GO:0030529,GO:0032797,GO:0006412","RNA binding,tRNA binding,ribosome binding,RNA-dependent ATPase activity,ATP-dependent 5'-3' RNA helicase activity,ribonucleoprotein complex,SMN complex,translation","GO:0043141,GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0005524,GO:0003676,GO:0003677,GO:0016787,GO:0000049,GO:0003697,GO:0017111,GO:0008134,GO:0008094,GO:0003678,GO:0043022,GO:0008186,GO:0032575,GO:0005634,GO:0005737,GO:0030424,GO:0030529,GO:0030426,GO:0032797,GO:0006351,GO:0051260,GO:0006412,GO:0006355,GO:0006281,GO:0006310,GO:0006260,GO:0008219,GO:0032508","ATP-dependent 5'-3' DNA helicase activity,nucleotide binding,RNA binding,protein binding,zinc ion binding,ATP binding,nucleic acid binding,DNA binding,hydrolase activity,tRNA binding,single-stranded DNA binding,nucleoside-triphosphatase activity,transcription factor binding,DNA-dependent ATPase activity,DNA helicase activity,ribosome binding,RNA-dependent ATPase activity,ATP-dependent 5'-3' RNA helicase activity,nucleus,cytoplasm,axon,ribonucleoprotein complex,growth cone,SMN complex,transcription, DNA-templated,protein homooligomerization,translation,regulation of transcription, DNA-dependent,DNA repair,DNA recombination,DNA replication,cell death,DNA duplex unwinding"," SPINAL MUSCULAR ATROPHY, DISTAL, AUTOSOMAL RECESSIVE, 1; DSMA1"]
["PAPD5","PAP associated domain containing 5 [Source:HGNC Symbol;Acc:30758]","ENSG00000121274","ENSP00000396995",2,"PAP_assoc[1],NTP_transf_2[1]","family-576","PAPD5,PAPD7","PAPD5","PAPD7[39,51]","diverse","diverse","21878619, TRAMP complex","RNAbinding","novel",1,1,".",".","GO:0071044","histone mRNA catabolic process","GO:0016779,GO:0046872,GO:0003677,GO:0003887,GO:0005634,GO:0005737,GO:0007067,GO:0071044","nucleotidyltransferase activity,metal ion binding,DNA binding,DNA-directed DNA polymerase activity,nucleus,cytoplasm,mitosis,histone mRNA catabolic process","."]
["PAPD7","PAP associated domain containing 7 [Source:HGNC Symbol;Acc:16705]","ENSG00000112941","ENSP00000230859",2,"PAP_assoc[1],NTP_transf_2[1]","family-576","PAPD5,PAPD7","PAPD5","PAPD7[39,51]","diverse","diverse","21878619, TRAMP complex",".",".",".",".",".",".",".",".","GO:0046872,GO:0003677,GO:0016779,GO:0003887,GO:0043221,GO:0005634,GO:0042493,GO:0006302,GO:0007076,GO:0007062","metal ion binding,DNA binding,nucleotidyltransferase activity,DNA-directed DNA polymerase activity,SMC family protein binding,nucleus,response to drug,double-strand break repair,mitotic chromosome condensation,sister chromatid cohesion","."]
["GFM2","G elongation factor, mitochondrial 2 [Source:HGNC Symbol;Acc:29682]","ENSG00000164347","ENSP00000427004",5,"EFG_C[1],GTP_EFTU_D2[1],EFG_IV[1],EFG_II[1],GTP_EFTU[1]","family-577","GFM2",".",".","mRNA","mRNA","This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]",".",".",".",".",".",".","GO:0032543,GO:0032790","mitochondrial translation,ribosome disassembly","GO:0005525,GO:0003924,GO:0005739,GO:0006184,GO:0032543,GO:0032790","GTP binding,GTPase activity,mitochondrion,GTP catabolic process,mitochondrial translation,ribosome disassembly","."]
["PHRF1","PHD and ring finger domains 1 [Source:HGNC Symbol;Acc:24351] [Type: protein coding Ensembl/Havana merge]","ENSG00000070047","ENSP00000410626",2,"PHD[1],zf-RING_2[1]","family-578","PHRF1",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",".","GO:0006397","mRNA processing","GO:0070063,GO:0005515,GO:0008270,GO:0046872,GO:0019904,GO:0006366,GO:0006397","RNA polymerase binding,protein binding,zinc ion binding,metal ion binding,protein domain specific binding,transcription from RNA polymerase II promoter,mRNA processing","."]
["VARS","valyl-tRNA synthetase [Source:HGNC Symbol;Acc:12651]","ENSG00000096171","ENSP00000211402",4,"GST_C[1],GST_N[1],Anticodon_1[1],tRNA-synt_1[1]","family-579","VARS,VARS2","VARS","VARS2[41,47]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0006418,GO:0004832,GO:0002161,GO:0006438,GO:0006414","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valine-tRNA ligase activity,aminoacyl-tRNA editing activity,valyl-tRNA aminoacylation,translational elongation","GO:0000166,GO:0005524,GO:0004812,GO:0006418,GO:0004832,GO:0002161,GO:0006438,GO:0005515,GO:0005739,GO:0005829,GO:0005622,GO:0010467,GO:0006414","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valine-tRNA ligase activity,aminoacyl-tRNA editing activity,valyl-tRNA aminoacylation,protein binding,mitochondrion,cytosol,intracellular,gene expression,translational elongation","."]
["VARS2","valyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:21642]","ENSG00000137411","ENSP00000316092",2,"Anticodon_1[1],tRNA-synt_1[1]","family-579","VARS,VARS2","VARS","VARS2[41,47]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004832,GO:0002161,GO:0004812,GO:0006418,GO:0006438","valine-tRNA ligase activity,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004832,GO:0002161,GO:0004812,GO:0006418,GO:0006438,GO:0005739,GO:0010467","nucleotide binding,ATP binding,valine-tRNA ligase activity,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,valyl-tRNA aminoacylation,mitochondrion,gene expression","."]
["MRPL1","mitochondrial ribosomal protein L1 [Source:HGNC Symbol;Acc:14275]","ENSG00000169288","ENSP00000426575",1,"Ribosomal_L1[1]","family-58","MRPL1",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003723,GO:0003735,GO:0015934,GO:0006412","RNA binding,structural constituent of ribosome,large ribosomal subunit,translation","GO:0003723,GO:0003735,GO:0005739,GO:0015934,GO:0006412","RNA binding,structural constituent of ribosome,mitochondrion,large ribosomal subunit,translation","."]
["INTS7","integrator complex subunit 7 [Source:HGNC Symbol;Acc:24484] [Type: protein coding Ensembl/Havana merge]","ENSG00000143493","ENSP00000355961",".",".","family-580","INTS7",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005488,GO:0005515,GO:0005694,GO:0032039,GO:0000077,GO:0071479,GO:0016180","binding,protein binding,chromosome,integrator complex,DNA damage checkpoint,cellular response to ionizing radiation,snRNA processing","."]
["ATXN2L","ataxin 2-like [Source:HGNC Symbol;Acc:31326]","ENSG00000168488","ENSP00000372133",3,"PAM2[1],LsmAD[1],SM-ATX[1]","family-581","ATXN2,ATXN2L","ATXN2","ATXN2L[32,38]","mRNA","putative mRNA",17392519,"RNAbinding","novel",1,1,".",".","GO:0010494,GO:0010603","cytoplasmic stress granule,regulation of cytoplasmic mRNA processing body assembly","GO:0005515,GO:0016020,GO:0010494,GO:0016607,GO:0034063,GO:0010603","protein binding,membrane,cytoplasmic stress granule,nuclear speck,stress granule assembly,regulation of cytoplasmic mRNA processing body assembly","."]
["ATXN2","ataxin 2 [Source:HGNC Symbol;Acc:10555]","ENSG00000204842","ENSP00000445583",3,"PAM2[1],LsmAD[1],SM-ATX[1]","family-581","ATXN2,ATXN2L","ATXN2","ATXN2L[32,38]","mRNA","mRNA","17392519, 10814712","RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0030529,GO:0010494,GO:0016070,GO:0006417,GO:0033962,GO:0050658","RNA binding,ribonucleoprotein complex,cytoplasmic stress granule,RNA metabolic process,regulation of translation,cytoplasmic mRNA processing body assembly,RNA transport","GO:0003723,GO:0005515,GO:0005154,GO:0008022,GO:0005634,GO:0005737,GO:0048471,GO:0005794,GO:0005802,GO:0030529,GO:0010494,GO:0005844,GO:0016070,GO:0006417,GO:0040015,GO:0021702,GO:0008219,GO:0034063,GO:0048872,GO:0048812,GO:0002091,GO:0050905,GO:0033962,GO:0050658","RNA binding,protein binding,epidermal growth factor receptor binding,protein C-terminus binding,nucleus,cytoplasm,perinuclear region of cytoplasm,Golgi apparatus,trans-Golgi network,ribonucleoprotein complex,cytoplasmic stress granule,polysome,RNA metabolic process,regulation of translation,negative regulation of multicellular organism growth,cerebellar Purkinje cell differentiation,cell death,stress granule assembly,homeostasis of number of cells,neuron projection morphogenesis,negative regulation of receptor internalization,neuromuscular process,cytoplasmic mRNA processing body assembly,RNA transport"," SPINOCEREBELLAR ATAXIA 2; SCA2"]
["PPIL4","peptidylprolyl isomerase (cyclophilin)-like 4 [Source:HGNC Symbol;Acc:15702]","ENSG00000131013","ENSP00000253329",2,"RRM_1[1],Pro_isomerase[1]","family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","PPIB","PPWD1[38,13],PPIL1[37,48],CWC27[29,13],PPIL3[26,35],PPIC[63,65],PPIL4[29,13],PPIL2[35,14],PPIH[44,54]","mRNA","putative mRNA",11978968,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0003755,GO:0005634,GO:0006457","nucleotide binding,RNA binding,nucleic acid binding,peptidyl-prolyl cis-trans isomerase activity,nucleus,protein folding","."]
["PPIL3","peptidylprolyl isomerase (cyclophilin)-like 3 [Source:HGNC Symbol;Acc:9262]","ENSG00000240344","ENSP00000286175",1,"Pro_isomerase[1]","family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","PPIB","PPWD1[38,13],PPIL1[37,48],CWC27[29,13],PPIL3[26,35],PPIC[63,65],PPIL4[29,13],PPIL2[35,14],PPIH[44,54]","mRNA","putative mRNA",11991638,".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0003755,GO:0006457,GO:0005515,GO:0071013,GO:0000398","peptidyl-prolyl cis-trans isomerase activity,protein folding,protein binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["PPWD1","peptidylprolyl isomerase domain and WD repeat containing 1 [Source:HGNC Symbol;Acc:28954]","ENSG00000113593","ENSP00000261308",3,"Pro_isomerase[1],WD40[2]","family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","PPIB","PPWD1[38,13],PPIL1[37,48],CWC27[29,13],PPIL3[26,35],PPIC[63,65],PPIL4[29,13],PPIL2[35,14],PPIH[44,54]","mRNA","putative mRNA",18397323,".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0003755,GO:0005634,GO:0006457,GO:0071013,GO:0000398","protein binding,peptidyl-prolyl cis-trans isomerase activity,nucleus,protein folding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["CWC27","CWC27 spliceosome-associated protein homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:10664]","ENSG00000153015","ENSP00000370460",1,"Pro_isomerase[1]","family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","PPIB","PPWD1[38,13],PPIL1[37,48],CWC27[29,13],PPIL3[26,35],PPIC[63,65],PPIL4[29,13],PPIL2[35,14],PPIH[44,54]","mRNA","mRNA","by homology, 22365833",".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0003755,GO:0006457,GO:0005634,GO:0071013,GO:0000398","peptidyl-prolyl cis-trans isomerase activity,protein folding,nucleus,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["PPIH","peptidylprolyl isomerase H (cyclophilin H) [Source:HGNC Symbol;Acc:14651]","ENSG00000171960","ENSP00000306614",1,"Pro_isomerase[1]","family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","PPIB","PPWD1[38,13],PPIL1[37,48],CWC27[29,13],PPIL3[26,35],PPIC[63,65],PPIL4[29,13],PPIL2[35,14],PPIH[44,54]","mRNA","putative mRNA","The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0043021,GO:0005681,GO:0046540,GO:0071001,GO:0000398","ribonucleoprotein complex binding,spliceosomal complex,U4/U6 x U5 tri-snRNP complex,U4/U6 snRNP,mRNA splicing, via spliceosome","GO:0003755,GO:0006457,GO:0005515,GO:0043021,GO:0016018,GO:0005737,GO:0005681,GO:0046540,GO:0016607,GO:0071001,GO:0000398,GO:0006461,GO:0045070,GO:0000413","peptidyl-prolyl cis-trans isomerase activity,protein folding,protein binding,ribonucleoprotein complex binding,cyclosporin A binding,cytoplasm,spliceosomal complex,U4/U6 x U5 tri-snRNP complex,nuclear speck,U4/U6 snRNP,mRNA splicing, via spliceosome,protein complex assembly,positive regulation of viral genome replication,protein peptidyl-prolyl isomerization","."]
["NUTF2","nuclear transport factor 2 [Source:HGNC Symbol;Acc:13722]","ENSG00000102898","ENSP00000457022",1,"NTF2[1]","family-583","NUTF2",".",".","mRNA","putative mRBP transport","by domain",".",".",".",".",".",".",".",".","GO:0005515,GO:0005215,GO:0005829,GO:0005622,GO:0005643,GO:0015630,GO:0006611,GO:0006810","protein binding,transporter activity,cytosol,intracellular,nuclear pore,microtubule cytoskeleton,protein export from nucleus,transport","."]
["MRPL18","mitochondrial ribosomal protein L18 [Source:HGNC Symbol;Acc:14477]","ENSG00000112110","ENSP00000356001",1,"Ribosomal_L18p[1]","family-584","MRPL18",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0008097,GO:0005840,GO:0005761,GO:0006412,GO:0035928","structural constituent of ribosome,5S rRNA binding,ribosome,mitochondrial ribosome,translation,rRNA import into mitochondrion","GO:0003735,GO:0008097,GO:0005739,GO:0005622,GO:0005840,GO:0005761,GO:0006412,GO:0035928","structural constituent of ribosome,5S rRNA binding,mitochondrion,intracellular,ribosome,mitochondrial ribosome,translation,rRNA import into mitochondrion","."]
["LSM11","LSM11, U7 small nuclear RNA associated [Source:HGNC Symbol;Acc:30860]","ENSG00000155858","ENSP00000286307",2,"LSM[2]","family-585","LSM11",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0071209,GO:0071204,GO:0005683,GO:0006398,GO:0031124,GO:0008334","U7 snRNA binding,histone pre-mRNA 3'end processing complex,U7 snRNP,histone mRNA 3'-end processing,mRNA 3'-end processing,histone mRNA metabolic process","GO:0005515,GO:0071209,GO:0071204,GO:0005634,GO:0005654,GO:0005683,GO:0006398,GO:0006366,GO:0010467,GO:0031124,GO:0000084,GO:0006369,GO:0008334","protein binding,U7 snRNA binding,histone pre-mRNA 3'end processing complex,nucleus,nucleoplasm,U7 snRNP,histone mRNA 3'-end processing,transcription from RNA polymerase II promoter,gene expression,mRNA 3'-end processing,mitotic S phase,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["AARS2","alanyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:21022]","ENSG00000124608","ENSP00000244571",2,"tRNA_SAD[1],tRNA-synt_2c[1]","family-586","AARS,AARS2","AARS","AARS2[45,44]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000049,GO:0004813,GO:0016876,GO:0006418,GO:0006419,GO:0043039,GO:0070143","tRNA binding,alanine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,tRNA aminoacylation for protein translation,alanyl-tRNA aminoacylation,tRNA aminoacylation,mitochondrial alanyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0003676,GO:0046872,GO:0000049,GO:0004813,GO:0016876,GO:0005739,GO:0005737,GO:0010467,GO:0006418,GO:0006419,GO:0043039,GO:0033108,GO:0070143","nucleotide binding,ATP binding,nucleic acid binding,metal ion binding,tRNA binding,alanine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,mitochondrion,cytoplasm,gene expression,tRNA aminoacylation for protein translation,alanyl-tRNA aminoacylation,tRNA aminoacylation,mitochondrial respiratory chain complex assembly,mitochondrial alanyl-tRNA aminoacylation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 8; COXPD8"]
["AARS","alanyl-tRNA synthetase [Source:HGNC Symbol;Acc:20]","ENSG00000090861","ENSP00000261772",3,"tRNA_SAD[1],DHHA1[1],tRNA-synt_2c[1]","family-586","AARS,AARS2","AARS","AARS2[45,44]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004813,GO:0016876,GO:0006419,GO:0043039,GO:0000049,GO:0002161,GO:0006450,GO:0008033,GO:0006418,GO:0006400","alanine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,alanyl-tRNA aminoacylation,tRNA aminoacylation,tRNA binding,aminoacyl-tRNA editing activity,regulation of translational fidelity,tRNA processing,tRNA aminoacylation for protein translation,tRNA modification","GO:0000166,GO:0005524,GO:0003676,GO:0004813,GO:0016876,GO:0006419,GO:0043039,GO:0046872,GO:0000049,GO:0002161,GO:0016597,GO:0005737,GO:0005829,GO:0043588,GO:0050905,GO:0006450,GO:0034620,GO:0006457,GO:0010467,GO:0008033,GO:0050885,GO:0043524,GO:0043200,GO:0001942,GO:0006418,GO:0030968,GO:0021680,GO:0006400","nucleotide binding,ATP binding,nucleic acid binding,alanine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,alanyl-tRNA aminoacylation,tRNA aminoacylation,metal ion binding,tRNA binding,aminoacyl-tRNA editing activity,amino acid binding,cytoplasm,cytosol,skin development,neuromuscular process,regulation of translational fidelity,cellular response to unfolded protein,protein folding,gene expression,tRNA processing,neuromuscular process controlling balance,negative regulation of neuron apoptotic process,response to amino acid,hair follicle development,tRNA aminoacylation for protein translation,endoplasmic reticulum unfolded protein response,cerebellar Purkinje cell layer development,tRNA modification"," CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2N; CMT2N"]
["MIF4GD","MIF4G domain containing [Source:HGNC Symbol;Acc:24030]","ENSG00000125457","ENSP00000463493",1,"MIF4G[1]","family-587","CTIF,MIF4GD","CTIF","MIF4GD[12,27]","mRNA","mRNA",22532700,".",".",".",".",".",".","GO:0003723,GO:0006417","RNA binding,regulation of translation","GO:0003723,GO:0005515,GO:0005488,GO:0008022,GO:0005634,GO:0005737,GO:0006417","RNA binding,protein binding,binding,protein C-terminus binding,nucleus,cytoplasm,regulation of translation","."]
["CTIF","CBP80/20-dependent translation initiation factor [Source:HGNC Symbol;Acc:23925]","ENSG00000134030","ENSP00000372459",1,"MIF4G[1]","family-587","CTIF,MIF4GD","CTIF","MIF4GD[12,27]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0006446,GO:0000184","RNA binding,regulation of translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0003723,GO:0005515,GO:0005488,GO:0005737,GO:0048471,GO:0006446,GO:0000184","RNA binding,protein binding,binding,cytoplasm,perinuclear region of cytoplasm,regulation of translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["C9orf129","chromosome 9 open reading frame 129 [Source:HGNC Symbol;Acc:31116]","ENSG00000204352","ENSP00000364568",".",".","family-588","C9orf129",".",".","unknown","unknown","by homology to FAM120A",".",".",".",".",".",".",".",".",".",".","."]
["LUC7L2","C7orf55-LUC7L2 protein  [Source:RefSeq peptide;Acc:NP_001231513]","ENSG00000269955","ENSP00000440222",1,"LUC7[1]","family-589","LUC7L,LUC7L2,LUC7L3","LUC7L","LUC7L2[71,58],LUC7L3[32,28]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,".",".","GO:0003729,GO:0005685,GO:0006376","mRNA binding,U1 snRNP,mRNA splice site selection","GO:0003729,GO:0005685,GO:0006376","mRNA binding,U1 snRNP,mRNA splice site selection","."]
["LUC7L3","LUC7-like 3 (S. cerevisiae) [Source:HGNC Symbol;Acc:24309]","ENSG00000108848","ENSP00000376919",1,"LUC7[1]","family-589","LUC7L,LUC7L2,LUC7L3","LUC7L","LUC7L2[71,58],LUC7L3[32,28]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0003729,GO:0005685,GO:0006376,GO:0008380","mRNA binding,U1 snRNP,mRNA splice site selection,RNA splicing","GO:0003729,GO:0005634,GO:0005886,GO:0005925,GO:0005685,GO:0006376,GO:0005515,GO:0003677,GO:0016607,GO:0008380","mRNA binding,nucleus,plasma membrane,focal adhesion,U1 snRNP,mRNA splice site selection,protein binding,DNA binding,nuclear speck,RNA splicing","."]
["LUC7L","LUC7-like (S. cerevisiae) [Source:HGNC Symbol;Acc:6723]","ENSG00000007392","ENSP00000293872",1,"LUC7[1]","family-589","LUC7L,LUC7L2,LUC7L3","LUC7L","LUC7L2[71,58],LUC7L3[32,28]","mRNA","mRNA/snRNA","The LUC7L gene may represent a mammalian heterochromatic gene, encoding a putative RNA-binding protein similar to the yeast Luc7p subunit of the U1 snRNP splicing complex that is normally required for 5-prime splice site selection (Tufarelli et al., 2001 [PubMed 11170747]).[supplied by OMIM, Mar 2008]",".",".",".",".",1,".","GO:0003729,GO:0005685,GO:0006376","mRNA binding,U1 snRNP,mRNA splice site selection","GO:0003729,GO:0050733,GO:0005685,GO:0006376,GO:0045843,GO:0005515,GO:0042802,GO:0005634","mRNA binding,RS domain binding,U1 snRNP,mRNA splice site selection,negative regulation of striated muscle tissue development,protein binding,identical protein binding,nucleus","."]
["DUS2","dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26014]","ENSG00000167264","ENSP00000409498",2,"dsrm[1],Dus[1]","family-59","DUS2",".",".","tRNA","tRNA","This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]",".",".",".",".",".",".","GO:0017150,GO:0008033,GO:0003725","tRNA dihydrouridine synthase activity,tRNA processing,double-stranded RNA binding","GO:0050660,GO:0017150,GO:0005739,GO:0055114,GO:0008033,GO:0005737,GO:0005515,GO:0003725,GO:0004860,GO:0005783,GO:0006469,GO:0060548","flavin adenine dinucleotide binding,tRNA dihydrouridine synthase activity,mitochondrion,oxidation-reduction process,tRNA processing,cytoplasm,protein binding,double-stranded RNA binding,protein kinase inhibitor activity,endoplasmic reticulum,negative regulation of protein kinase activity,negative regulation of cell death","."]
["RNF17","ring finger protein 17 [Source:HGNC Symbol;Acc:10060]","ENSG00000132972","ENSP00000255324",5,"TUDOR[5]","family-590","RNF17,TDRD1","RNF17","TDRD1[14,20]","mRNA","mRNA/piRNA/ncRNA",11675789,".",".",".",".",".",".",".",".","GO:0005515,GO:0042803,GO:0008270,GO:0003676,GO:0016788,GO:0005634,GO:0005737,GO:0007275,GO:0007286","protein binding,protein homodimerization activity,zinc ion binding,nucleic acid binding,hydrolase activity, acting on ester bonds,nucleus,cytoplasm,multicellular organismal development,spermatid development","."]
["TDRD1","tudor domain containing 1 [Source:HGNC Symbol;Acc:11712]","ENSG00000095627","ENSP00000358288",5,"TUDOR[4],zf-MYND[1]","family-590","RNF17,TDRD1","RNF17","TDRD1[14,20]","ncRNA","piRNA related",22996915,".",".",".",".",".",".","GO:0030529,GO:0043186,GO:0071546,GO:0031047,GO:0034587","ribonucleoprotein complex,P granule,pi-body,gene silencing by RNA,piRNA metabolic process","GO:0046872,GO:0005515,GO:0005737,GO:0030529,GO:0043186,GO:0071546,GO:0033391,GO:0007281,GO:0007283,GO:0043046,GO:0031047,GO:0034587,GO:0007275,GO:0007126","metal ion binding,protein binding,cytoplasm,ribonucleoprotein complex,P granule,pi-body,chromatoid body,germ cell development,spermatogenesis,DNA methylation involved in gamete generation,gene silencing by RNA,piRNA metabolic process,multicellular organismal development,meiosis","."]
["MRPS10","mitochondrial ribosomal protein S10 [Source:HGNC Symbol;Acc:14502]","ENSG00000048544","ENSP00000053468",1,"Ribosomal_S10[1]","family-591","MRPS10",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0005739,GO:0005840","mitochondrion,ribosome","."]
["FAM103A1","family with sequence similarity 103, member A1 [Source:HGNC Symbol;Acc:31022]","ENSG00000169612","ENSP00000307181",1,"RAM[1]","family-592","FAM103A1",".",".","mRNA","mRNA","FAM103A1 mRNA capping","RNAbinding",".",".",1,".",".","GO:0003723,GO:0005845,GO:0006370","RNA binding,mRNA cap binding complex,7-methylguanosine mRNA capping","GO:0003723,GO:0005515,GO:0005634,GO:0005845,GO:0006370,GO:0032259,GO:0036031","RNA binding,protein binding,nucleus,mRNA cap binding complex,7-methylguanosine mRNA capping,methylation,recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex","."]
["ENOX1","ecto-NOX disulfide-thiol exchanger 1 [Source:HGNC Symbol;Acc:25474]","ENSG00000120658","ENSP00000415054",1,"RRM_1[1]","family-593","ENOX1,ENOX2","ENOX1","ENOX2[63,67]","mRNA","putative mRNA","by domain",".",".",".",".",1,1,".",".","GO:0000166,GO:0016491,GO:0003676,GO:0005886,GO:0005615,GO:0048511","nucleotide binding,oxidoreductase activity,nucleic acid binding,plasma membrane,extracellular space,rhythmic process","."]
["ENOX2","ecto-NOX disulfide-thiol exchanger 2 [Source:HGNC Symbol;Acc:2259]","ENSG00000165675","ENSP00000359965",1,"RRM_1[1]","family-593","ENOX1,ENOX2","ENOX1","ENOX2[63,67]","mRNA","putative mRNA","by domain",".",".",".",".",".",1,".",".","GO:0000166,GO:0003676,GO:0015035,GO:0005829,GO:0005615,GO:0009897,GO:0055114,GO:0040008,GO:0016049,GO:0007624","nucleotide binding,nucleic acid binding,protein disulfide oxidoreductase activity,cytosol,extracellular space,external side of plasma membrane,oxidation-reduction process,regulation of growth,cell growth,ultradian rhythm","."]
["RBPMS","RNA binding protein with multiple splicing [Source:HGNC Symbol;Acc:19097]","ENSG00000157110","ENSP00000318102",1,"RRM_1[1]","family-594","RBPMS,RBPMS2","RBPMS","RBPMS2[57,60]","mRNA","mRNA","established RBP ",".","experimentally validated",".",1,1,1,"GO:0008143,GO:0006396","poly(A) RNA binding,RNA processing","GO:0000166,GO:0003676,GO:0005515,GO:0003713,GO:0008143,GO:0005634,GO:0005737,GO:0006351,GO:0006355,GO:0006396,GO:0010862,GO:0060391","nucleotide binding,nucleic acid binding,protein binding,transcription coactivator activity,poly(A) RNA binding,nucleus,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent,RNA processing,positive regulation of pathway-restricted SMAD protein phosphorylation,positive regulation of SMAD protein import into nucleus","."]
["RBPMS2","RNA binding protein with multiple splicing 2 [Source:HGNC Symbol;Acc:19098]","ENSG00000166831","ENSP00000300069",1,"RRM_1[1]","family-594","RBPMS,RBPMS2","RBPMS","RBPMS2[57,60]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,".",".","GO:0000166,GO:0003676","nucleotide binding,nucleic acid binding","."]
["NIP7","nuclear import 7 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24328]","ENSG00000132603","ENSP00000464159",1,"UPF0113[1]","family-595","NIP7",".",".","rRNA","rRNA",22195017,"ribosomal","RNAbinding",1,1,1,1,"GO:0003723,GO:0042255","RNA binding,ribosome assembly","GO:0003723,GO:0005515,GO:0005730,GO:0042255,GO:0005634","RNA binding,protein binding,nucleolus,ribosome assembly,nucleus","."]
["RPL3","ribosomal protein L3 [Source:HGNC Symbol;Acc:10332]","ENSG00000100316","ENSP00000386101",1,"Ribosomal_L3[1]","family-596","RPL3,RPL3L","RPL3","RPL3L[77,76]","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005737,GO:0005730,GO:0071353,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,cytoplasm,nucleolus,cellular response to interleukin-4,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL3L","ribosomal protein L3-like [Source:HGNC Symbol;Acc:10351]","ENSG00000140986","ENSP00000268661",1,"Ribosomal_L3[1]","family-596","RPL3,RPL3L","RPL3","RPL3L[77,76]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RNASE11","ribonuclease, RNase A family, 11 (non-active) [Source:HGNC Symbol;Acc:19269]","ENSG00000173464","ENSP00000381093",1,"RnaseA[1]","family-597","RNASE11,RNASE12","RNASE11","RNASE12[54,35]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016892,GO:0005576","nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region","."]
["RNASE12","Probable inactive ribonuclease-like protein 12  [Source:UniProtKB/Swiss-Prot;Acc:Q5GAN4]","ENSG00000258436","ENSP00000450580",1,"RnaseA[1]","family-597","RNASE11,RNASE12","RNASE11","RNASE12[54,35]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016892,GO:0005576","nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region","."]
["RPLP0","ribosomal protein, large, P0 [Source:HGNC Symbol;Acc:10371]","ENSG00000089157","ENSP00000366471",2,"Ribosomal_L10[1],Ribosomal_60s[1]","family-598","RPLP0",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003723,GO:0003735,GO:0005840,GO:0030529,GO:0022625,GO:0006412,GO:0042254,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,ribonucleoprotein complex,cytosolic large ribosomal subunit,translation,ribosome biogenesis,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0005634,GO:0005737,GO:0005829,GO:0005622,GO:0005840,GO:0030529,GO:0022625,GO:0006412,GO:0042254,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019048,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,nucleus,cytoplasm,cytosol,intracellular,ribosome,ribonucleoprotein complex,cytosolic large ribosomal subunit,translation,ribosome biogenesis,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,modulation by virus of host morphology or physiology,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RBM34","RNA binding motif protein 34 [Source:HGNC Symbol;Acc:28965]","ENSG00000188739","ENSP00000355565",2,"RRM_1[2]","family-599","RBM34",".",".","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005730","nucleotide binding,RNA binding,nucleic acid binding,nucleus,nucleolus","."]
["CMTR2","cap methyltransferase 2 [Source:HGNC Symbol;Acc:25635]","ENSG00000180917","ENSP00000411148",1,"FtsJ[1]","family-6","CMTR2",".",".","mRNA","mRNA/snRNA",20713356,".",".",".",".",".",".","GO:0004483,GO:0006370","mRNA (nucleoside-2'-O-)-methyltransferase activity,7-methylguanosine mRNA capping","GO:0008168,GO:0004483,GO:0016021,GO:0005634,GO:0005737,GO:0006370,GO:0032259,GO:0097310","methyltransferase activity,mRNA (nucleoside-2'-O-)-methyltransferase activity,integral to membrane,nucleus,cytoplasm,7-methylguanosine mRNA capping,methylation,cap2 mRNA methylation","."]
["ENDOU","endonuclease, polyU-specific [Source:HGNC Symbol;Acc:14369]","ENSG00000111405","ENSP00000397679",3,"XendoU[1],Somatomedin_B[2]","family-60","ENDOU",".",".","snoRNA","snoRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004521","RNA binding,endoribonuclease activity","GO:0016788,GO:0003723,GO:0008083,GO:0005044,GO:0030145,GO:0030247,GO:0008236,GO:0004521,GO:0005886,GO:0005737,GO:0005576,GO:0005615,GO:0006508,GO:0006955,GO:0007565","hydrolase activity, acting on ester bonds,RNA binding,growth factor activity,scavenger receptor activity,manganese ion binding,polysaccharide binding,serine-type peptidase activity,endoribonuclease activity,plasma membrane,cytoplasm,extracellular region,extracellular space,proteolysis,immune response,female pregnancy","."]
["PUM1","pumilio homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:14957]","ENSG00000134644","ENSP00000433850",9,"Shadoo[1],PUF[8]","family-600","PUM1,PUM2","PUM1","PUM2[70,78]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006417","RNA binding,regulation of translation","GO:0005488,GO:0003723,GO:0005829,GO:0006417,GO:0006892","binding,RNA binding,cytosol,regulation of translation,post-Golgi vesicle-mediated transport","."]
["PUM2","pumilio homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:14958]","ENSG00000055917","ENSP00000385992",8,"PUF[8]","family-600","PUM1,PUM2","PUM1","PUM2[70,78]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0010494,GO:0006417","RNA binding,cytoplasmic stress granule,regulation of translation","GO:0005488,GO:0003723,GO:0005737,GO:0010494,GO:0034063,GO:0005515,GO:0048471,GO:0006417","binding,RNA binding,cytoplasm,cytoplasmic stress granule,stress granule assembly,protein binding,perinuclear region of cytoplasm,regulation of translation","."]
["TYW5","tRNA-yW synthesizing protein 5 [Source:HGNC Symbol;Acc:26754]","ENSG00000162971","ENSP00000346627",1,"Cupin_8[1]","family-601","HSPBAP1,HIF1AN,TYW5","HSPBAP1","HIF1AN[16,23],TYW5[15,23]","tRNA","tRNA",20972222,".",".",".",".",".",".","GO:0000049","tRNA binding","GO:0005515,GO:0042803,GO:0000049,GO:0005506,GO:0016706,GO:0031591","protein binding,protein homodimerization activity,tRNA binding,iron ion binding,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors,wybutosine biosynthetic process","."]
["TYW3","tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24757]","ENSG00000162623","ENSP00000359904",1,"TYW3[1]","family-602","TYW3",".",".","tRNA","putative tRNA","Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]  17150819",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0008168,GO:0008033","methyltransferase activity,tRNA processing","."]
["TRMT1","tRNA methyltransferase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25980]","ENSG00000104907","ENSP00000466967",2,"TRM[1],zf-CCCH[1]","family-603","TRMT1",".",".","tRNA","tRNA",1098286,".","RNAbinding",".",1,".",1,"GO:0003723,GO:0000049,GO:0004809,GO:0008033","RNA binding,tRNA binding,tRNA (guanine-N2-)-methyltransferase activity,tRNA processing","GO:0003723,GO:0046872,GO:0016740,GO:0000049,GO:0004809,GO:0008033","RNA binding,metal ion binding,transferase activity,tRNA binding,tRNA (guanine-N2-)-methyltransferase activity,tRNA processing","."]
["RAE1","RAE1 RNA export 1 homolog (S. pombe) [Source:HGNC Symbol;Acc:9828]","ENSG00000101146","ENSP00000379182",3,"WD40[3]","family-604","BUB3,RAE1","BUB3","RAE1[35,31]","mRNA","mRNA","Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0006406","RNA binding,mRNA export from nucleus","GO:0005515,GO:0071407,GO:0003723,GO:0008017,GO:0005634,GO:0005737,GO:0005856,GO:0005643,GO:0005635,GO:0005640,GO:0055085,GO:0044281,GO:0000278,GO:0016032,GO:0005975,GO:0019221,GO:0010827,GO:0015758,GO:0006406,GO:0007077,GO:0008645","protein binding,cellular response to organic cyclic compound,RNA binding,microtubule binding,nucleus,cytoplasm,cytoskeleton,nuclear pore,nuclear envelope,nuclear outer membrane,transmembrane transport,small molecule metabolic process,mitotic cell cycle,viral process,carbohydrate metabolic process,cytokine-mediated signaling pathway,regulation of glucose transport,glucose transport,mRNA export from nucleus,mitotic nuclear envelope disassembly,hexose transport","."]
["SLU7","SLU7 splicing factor homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:16939]","ENSG00000164609","ENSP00000297151",1,"Slu7[1]","family-605","SLU7",".",".","mRNA","mRNA",15728250,".",".",".",".",".",".","GO:0000386,GO:0030628,GO:0005681,GO:0030532,GO:0071013,GO:0000398,GO:0000380,GO:0000375,GO:0000389","second spliceosomal transesterification activity,pre-mRNA 3'-splice site binding,spliceosomal complex,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,alternative mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,mRNA 3'-splice site recognition","GO:0005515,GO:0008270,GO:0000386,GO:0030628,GO:0005634,GO:0005737,GO:0043231,GO:0005681,GO:0016607,GO:0030532,GO:0071013,GO:0006886,GO:0000398,GO:0034605,GO:0000380,GO:0000375,GO:0000389,GO:0003676","protein binding,zinc ion binding,second spliceosomal transesterification activity,pre-mRNA 3'-splice site binding,nucleus,cytoplasm,intracellular membrane-bounded organelle,spliceosomal complex,nuclear speck,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,intracellular protein transport,mRNA splicing, via spliceosome,cellular response to heat,alternative mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,mRNA 3'-splice site recognition,nucleic acid binding","."]
["EIF2B4","eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa [Source:HGNC Symbol;Acc:3260]","ENSG00000115211","ENSP00000394397",1,"IF-2B[1]","family-606","EIF2B4",".",".","mRNA","mRNA","eiF2B complex",".",".",".",".",".",".","GO:0003743,GO:0031369,GO:0005851,GO:0006412,GO:0006417,GO:0006446,GO:0006413","translation initiation factor activity,translation initiation factor binding,eukaryotic translation initiation factor 2B complex,translation,regulation of translation,regulation of translational initiation,translational initiation","GO:0044237,GO:0005515,GO:0005085,GO:0003743,GO:0031369,GO:0005737,GO:0005829,GO:0005851,GO:0006412,GO:0014003,GO:0010467,GO:0006417,GO:0009749,GO:0006446,GO:0001541,GO:0042552,GO:0009408,GO:0044267,GO:0043434,GO:0032057,GO:0045947,GO:0006413,GO:0051716","cellular metabolic process,protein binding,guanyl-nucleotide exchange factor activity,translation initiation factor activity,translation initiation factor binding,cytoplasm,cytosol,eukaryotic translation initiation factor 2B complex,translation,oligodendrocyte development,gene expression,regulation of translation,response to glucose,regulation of translational initiation,ovarian follicle development,myelination,response to heat,cellular protein metabolic process,response to peptide hormone,negative regulation of translational initiation in response to stress,negative regulation of translational initiation,translational initiation,cellular response to stimulus"," LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER; VWM"]
["EIF5B","eukaryotic translation initiation factor 5B [Source:HGNC Symbol;Acc:30793]","ENSG00000158417","ENSP00000289371",4,"GTP_EFTU_D2[1],IF-2[1],GTP_EFTU_D4[1],GTP_EFTU[1]","family-607","EIF5B",".",".","tRNA","tRNA",17568775,"translationfactor","novel",1,1,".",".","GO:0003743,GO:0006412,GO:0006446,GO:0006413","translation initiation factor activity,translation,regulation of translational initiation,translational initiation","GO:0005515,GO:0005525,GO:0003924,GO:0003743,GO:0005829,GO:0006412,GO:0010467,GO:0006446,GO:0044267,GO:0006413","protein binding,GTP binding,GTPase activity,translation initiation factor activity,cytosol,translation,gene expression,regulation of translational initiation,cellular protein metabolic process,translational initiation","."]
["GPATCH1","G patch domain containing 1 [Source:HGNC Symbol;Acc:24658]","ENSG00000076650","ENSP00000170564",3,"G-patch[1],Cwf_Cwc_15[1],DUF1604[1]","family-608","GPATCH1",".",".","mRNA","mRNA",11991638,".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0003676,GO:0071013,GO:0000398","nucleic acid binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["RPL36","ribosomal protein L36 [Source:HGNC Symbol;Acc:13631]","ENSG00000130255","ENSP00000464342",1,"Ribosomal_L36e[1]","family-609","RPL36",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005737,GO:0005829,GO:0005622,GO:0005730,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytoplasm,cytosol,intracellular,nucleolus,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["EEF1A1","eukaryotic translation elongation factor 1 alpha 1 [Source:HGNC Symbol;Acc:3189]","ENSG00000156508","ENSP00000339053",3,"GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-61","EEF1A1,EEF1A2","EEF1A1","EEF1A2[93,92]","tRNA","tRNA/mRNA",12354112,"translationfactor","novel",1,1,1,".","GO:0003746,GO:0005853,GO:0006412,GO:0006414","translation elongation factor activity,eukaryotic translation elongation factor 1 complex,translation,translational elongation","GO:0005525,GO:0003924,GO:0005886,GO:0005737,GO:0005515,GO:0019901,GO:0003746,GO:0005634,GO:0005829,GO:0005853,GO:0006351,GO:0006412,GO:0006355,GO:0010467,GO:0044267,GO:0006414","GTP binding,GTPase activity,plasma membrane,cytoplasm,protein binding,protein kinase binding,translation elongation factor activity,nucleus,cytosol,eukaryotic translation elongation factor 1 complex,transcription, DNA-templated,translation,regulation of transcription, DNA-dependent,gene expression,cellular protein metabolic process,translational elongation","."]
["EEF1A2","eukaryotic translation elongation factor 1 alpha 2 [Source:HGNC Symbol;Acc:3192]","ENSG00000101210","ENSP00000217182",3,"GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-61","EEF1A1,EEF1A2","EEF1A1","EEF1A2[93,92]","tRNA","tRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0003746,GO:0008135,GO:0005853,GO:0006414","translation elongation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation elongation factor 1 complex,translational elongation","GO:0005515,GO:0005525,GO:0003924,GO:0003746,GO:0008135,GO:0005634,GO:0005737,GO:0043025,GO:0005853,GO:1900119,GO:0043066,GO:0010035,GO:0006414","protein binding,GTP binding,GTPase activity,translation elongation factor activity,translation factor activity, nucleic acid binding,nucleus,cytoplasm,neuronal cell body,eukaryotic translation elongation factor 1 complex,positive regulation of execution phase of apoptosis,negative regulation of apoptotic process,response to inorganic substance,translational elongation","."]
["RRP8","ribosomal RNA processing 8, methyltransferase, homolog (yeast) [Source:HGNC Symbol;Acc:29030]","ENSG00000132275","ENSP00000254605",1,"Methyltransf_8[1]","family-610","RRP8",".",".","rRNA","rRNA","RRP8 homolog.  Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase; methylates adenine (m1A) of the large subunit (LSU) rRNA at position 645; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation; deletion disrupts telomere maintenance by influencing the expression of neighboring gene STN1","candidate mRNA binder","RNArelated",1,1,".",".","GO:0006364","rRNA processing","GO:0008168,GO:0008152,GO:0005515,GO:0035064,GO:0008757,GO:0005634,GO:0005886,GO:0005737,GO:0005730,GO:0005677,GO:0033553,GO:0006351,GO:0006364,GO:0016568,GO:0042149,GO:0000183,GO:0071158,GO:0046015,GO:0072332","methyltransferase activity,metabolic process,protein binding,methylated histone residue binding,S-adenosylmethionine-dependent methyltransferase activity,nucleus,plasma membrane,cytoplasm,nucleolus,chromatin silencing complex,rDNA heterochromatin,transcription, DNA-templated,rRNA processing,chromatin modification,cellular response to glucose starvation,chromatin silencing at rDNA,positive regulation of cell cycle arrest,regulation of transcription by glucose,intrinsic apoptotic signaling pathway by p53 class mediator","."]
["UBA52","ubiquitin A-52 residue ribosomal protein fusion product 1 [Source:HGNC Symbol;Acc:12458]","ENSG00000221983","ENSP00000472768",3,"ubiquitin[1],Ribosomal_L40e[2]","family-611","UBA52,UBB,ZFAND4,UBC,UBBP4","UBA52","UBB[73,41],ZFAND4[39,7],UBC[73,14],UBBP4[66,37]","ribosome","ribosome"," This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein L40 at the C terminus, a C-terminal extension protein (CEP). ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0003735,GO:0005840,GO:0006412,GO:0005886,GO:0005829,GO:0010008,GO:0005654,GO:0022625,GO:0005765,GO:0030666,GO:0000122,GO:0006351,GO:0045944,GO:0038095,GO:0045087,GO:0055085,GO:0006915,GO:0042981,GO:0043066,GO:0034220,GO:0043123,GO:0000209,GO:0006464,GO:0002474,GO:0000278,GO:0006281,GO:0016032,GO:0016197,GO:0019068,GO:0019082,GO:0002479,GO:0006977,GO:0010467,GO:0016070,GO:0016071,GO:0031145,GO:0042590,GO:0051437,GO:0051439,GO:0008585,GO:0000187,GO:0043065,GO:0032480,GO:0006367,GO:0007219,GO:0007254,GO:0019221,GO:0007179,GO:0030512,GO:0007141,GO:0071456,GO:0002224,GO:0072520,GO:0008543,GO:0051092,GO:0050852,GO:0044267,GO:0007173,GO:0032481,GO:0007249,GO:0000082,GO:0097190,GO:0002755,GO:0002756,GO:0034138,GO:0006614,GO:0034166,GO:0007220,GO:0051403,GO:0007144,GO:0010992,GO:0021888,GO:0060613,GO:0097009,GO:0042059,GO:0006414,GO:0034142,GO:0034162,GO:0048011,GO:0019058,GO:0034134,GO:0035666,GO:0038123,GO:0038124,GO:0051436,GO:0006413,GO:0034146,GO:0035872,GO:0061418,GO:0070423,GO:0000184,GO:0006415,GO:0019083,GO:0032479","protein binding,structural constituent of ribosome,ribosome,translation,plasma membrane,cytosol,endosome membrane,nucleoplasm,cytosolic large ribosomal subunit,lysosomal membrane,endocytic vesicle membrane,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,Fc-epsilon receptor signaling pathway,innate immune response,transmembrane transport,apoptotic process,regulation of apoptotic process,negative regulation of apoptotic process,ion transmembrane transport,positive regulation of I-kappaB kinase/NF-kappaB signaling,protein polyubiquitination,cellular protein modification process,antigen processing and presentation of peptide antigen via MHC class I,mitotic cell cycle,DNA repair,viral process,endosomal transport,virion assembly,viral protein processing,antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,gene expression,RNA metabolic process,mRNA metabolic process,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,antigen processing and presentation of exogenous peptide antigen via MHC class I,positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,female gonad development,activation of MAPK activity,positive regulation of apoptotic process,negative regulation of type I interferon production,transcription initiation from RNA polymerase II promoter,Notch signaling pathway,JNK cascade,cytokine-mediated signaling pathway,transforming growth factor beta receptor signaling pathway,negative regulation of transforming growth factor beta receptor signaling pathway,male meiosis I,cellular response to hypoxia,toll-like receptor signaling pathway,seminiferous tubule development,fibroblast growth factor receptor signaling pathway,positive regulation of NF-kappaB transcription factor activity,T cell receptor signaling pathway,cellular protein metabolic process,epidermal growth factor receptor signaling pathway,positive regulation of type I interferon production,I-kappaB kinase/NF-kappaB signaling,G1/S transition of mitotic cell cycle,apoptotic signaling pathway,MyD88-dependent toll-like receptor signaling pathway,MyD88-independent toll-like receptor signaling pathway,toll-like receptor 3 signaling pathway,SRP-dependent cotranslational protein targeting to membrane,toll-like receptor 10 signaling pathway,Notch receptor processing,stress-activated MAPK cascade,female meiosis I,ubiquitin homeostasis,hypothalamus gonadotrophin-releasing hormone neuron development,fat pad development,energy homeostasis,negative regulation of epidermal growth factor receptor signaling pathway,translational elongation,toll-like receptor 4 signaling pathway,toll-like receptor 9 signaling pathway,neurotrophin TRK receptor signaling pathway,viral life cycle,toll-like receptor 2 signaling pathway,TRIF-dependent toll-like receptor signaling pathway,toll-like receptor TLR1:TLR2 signaling pathway,toll-like receptor TLR6:TLR2 signaling pathway,negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,translational initiation,toll-like receptor 5 signaling pathway,nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway,regulation of transcription from RNA polymerase II promoter in response to hypoxia,nucleotide-binding oligomerization domain containing signaling pathway,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,regulation of type I interferon production","."]
["R3HDM1","R3H domain containing 1 [Source:HGNC Symbol;Acc:9757]","ENSG00000048991","ENSP00000264160",2,"SUZ[1],R3H[1]","family-612","ARPP21,R3HDM2,R3HDM1","ARPP21","R3HDM2[41,34],R3HDM1[46,34]","unknown","unknown","by domain","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0003676","nucleic acid binding","."]
["R3HDM2","R3H domain containing 2 [Source:HGNC Symbol;Acc:29167]","ENSG00000179912","ENSP00000385839",2,"SUZ[1],R3H[1]","family-612","ARPP21,R3HDM2,R3HDM1","ARPP21","R3HDM2[41,34],R3HDM1[46,34]","unknown","unknown","by domain",".","novel",".",1,1,".",".",".","GO:0003676,GO:0005634","nucleic acid binding,nucleus","."]
["PA2G4","proliferation-associated 2G4, 38kDa [Source:HGNC Symbol;Acc:8550]","ENSG00000170515","ENSP00000302886",1,"Peptidase_M24[1]","family-613","METAP2,PA2G4","METAP2","PA2G4[17,21]","rRNA","rRNA","This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]",".","experimentally validated",".",1,1,".","GO:0003723,GO:0030529,GO:0006417,GO:0006364","RNA binding,ribonucleoprotein complex,regulation of translation,rRNA processing","GO:0016787,GO:0003723,GO:0003700,GO:0005515,GO:0003677,GO:0031625,GO:0005634,GO:0005737,GO:0005730,GO:0030529,GO:0006351,GO:0008283,GO:0045892,GO:0006417,GO:0006364,GO:0007050","hydrolase activity,RNA binding,sequence-specific DNA binding transcription factor activity,protein binding,DNA binding,ubiquitin protein ligase binding,nucleus,cytoplasm,nucleolus,ribonucleoprotein complex,transcription, DNA-templated,cell proliferation,negative regulation of transcription, DNA-dependent,regulation of translation,rRNA processing,cell cycle arrest","."]
["AAR2","AAR2 splicing factor homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15886]","ENSG00000131043","ENSP00000380455",1,"AAR2[1]","family-614","AAR2",".",".","snRNA","snRNA",11720285,".",".",".",".",".",".",".",".",".",".","."]
["ERI1","exoribonuclease 1 [Source:HGNC Symbol;Acc:23994]","ENSG00000104626","ENSP00000430190",2,"SAP[1],RNase_T[1]","family-615","ERI1,ERI2,ERI3","ERI1","ERI2[24,12],ERI3[26,27]","rRNA","rRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0004527,GO:0019843,GO:0043022,GO:0008408,GO:0071207,GO:0071204,GO:0031047,GO:0031125","exonuclease activity,rRNA binding,ribosome binding,3'-5' exonuclease activity,histone pre-mRNA stem-loop binding,histone pre-mRNA 3'end processing complex,gene silencing by RNA,rRNA 3'-end processing","GO:0003676,GO:0004527,GO:0046872,GO:0019843,GO:0043022,GO:0008408,GO:0071207,GO:0005634,GO:0005737,GO:0005730,GO:0071204,GO:0031047,GO:0031125","nucleic acid binding,exonuclease activity,metal ion binding,rRNA binding,ribosome binding,3'-5' exonuclease activity,histone pre-mRNA stem-loop binding,nucleus,cytoplasm,nucleolus,histone pre-mRNA 3'end processing complex,gene silencing by RNA,rRNA 3'-end processing","."]
["ERI2","ERI1 exoribonuclease family member 2 [Source:HGNC Symbol;Acc:30541]","ENSG00000196678","ENSP00000454661",2,"zf-GRF[1],RNase_T[1]","family-615","ERI1,ERI2,ERI3","ERI1","ERI2[24,12],ERI3[26,27]","unknown","unknown","established RBP ",".",".",".",".",".",".","GO:0004527","exonuclease activity","GO:0008270,GO:0003676,GO:0004527","zinc ion binding,nucleic acid binding,exonuclease activity","."]
["ERI3","ERI1 exoribonuclease family member 3 [Source:HGNC Symbol;Acc:17276]","ENSG00000117419","ENSP00000438360",1,"RNase_T[1]","family-615","ERI1,ERI2,ERI3","ERI1","ERI2[24,12],ERI3[26,27]","unknown","unknown","established RBP ","nuclease","RNArelated",1,1,".",".","GO:0004527","exonuclease activity","GO:0003676,GO:0004527,GO:0005515,GO:0046872","nucleic acid binding,exonuclease activity,protein binding,metal ion binding","."]
["NIFK","MKI67 (FHA domain) interacting nucleolar phosphoprotein [Source:HGNC Symbol;Acc:17838]","ENSG00000155438","ENSP00000285814",2,"RRM_1[1],hNIFK_binding[1]","family-616","NIFK",".",".","rRNA","putative rRNA","This gene encodes a protein that interacts with the forkhead-associated domain of the Ki-67 antigen. The encoded protein may bind RNA and may play a role in mitosis and cell cycle progression. Multiple pseudogenes exist on chromosomes 5, 10, 12, 15, and 19.[provided by RefSeq, Jan 2009]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0009303,GO:0016072","RNA binding,rRNA transcription,rRNA metabolic process","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005737,GO:0005730,GO:0005654,GO:0000794,GO:0010923,GO:0006461,GO:0009303,GO:0016072","nucleotide binding,nucleic acid binding,RNA binding,protein binding,cytoplasm,nucleolus,nucleoplasm,condensed nuclear chromosome,negative regulation of phosphatase activity,protein complex assembly,rRNA transcription,rRNA metabolic process","."]
["METTL14","methyltransferase like 14 [Source:HGNC Symbol;Acc:29330]","ENSG00000145388","ENSP00000373474",1,"MT-A70[1]","family-617","METTL14",".",".","mRNA","putative mRNA",24481042,".",".",".",".",".",".","GO:0016422,GO:0001510","mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,RNA methylation","GO:0008168,GO:0006139,GO:0016422,GO:0005634,GO:0001510","methyltransferase activity,nucleobase-containing compound metabolic process,mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity,nucleus,RNA methylation","."]
["MRPL32","mitochondrial ribosomal protein L32 [Source:HGNC Symbol;Acc:14035]","ENSG00000106591","ENSP00000223324",1,"Ribosomal_L32p[1]","family-618","MRPL32",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0005840,GO:0003735,GO:0005761,GO:0015934,GO:0006412","ribosome,structural constituent of ribosome,mitochondrial ribosome,large ribosomal subunit,translation","GO:0005840,GO:0003735,GO:0005761,GO:0015934,GO:0006412","ribosome,structural constituent of ribosome,mitochondrial ribosome,large ribosomal subunit,translation","."]
["CPSF6","cleavage and polyadenylation specific factor 6, 68kDa [Source:HGNC Symbol;Acc:13871]","ENSG00000111605","ENSP00000391774",1,"RRM_6[1]","family-619","CPSF6,CPSF7","CPSF6","CPSF7[45,48]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0030529,GO:0005849,GO:0006397,GO:0006378","RNA binding,mRNA binding,ribonucleoprotein complex,mRNA cleavage factor complex,mRNA processing,mRNA polyadenylation","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003729,GO:0005634,GO:0030529,GO:0005849,GO:0042382,GO:0006397,GO:0051262,GO:0006378","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA binding,nucleus,ribonucleoprotein complex,mRNA cleavage factor complex,paraspeckles,mRNA processing,protein tetramerization,mRNA polyadenylation","."]
["CPSF7","cleavage and polyadenylation specific factor 7, 59kDa [Source:HGNC Symbol;Acc:30098]","ENSG00000149532","ENSP00000391359",1,"RRM_1[1]","family-619","CPSF6,CPSF7","CPSF6","CPSF7[45,48]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0005849,GO:0008380,GO:0000398,GO:0031124","RNA binding,mRNA cleavage factor complex,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005849,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0051262,GO:0031124,GO:0006369","nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleus,nucleoplasm,mRNA cleavage factor complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,protein tetramerization,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["RPL7A","ribosomal protein L7a [Source:HGNC Symbol;Acc:10364]","ENSG00000260501","ENSP00000455188",1,"Ribosomal_L7Ae[1]","family-62","RPL7A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0005840,GO:0042254,GO:0003723,GO:0003735,GO:0022625,GO:0042788,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","ribosome,ribosome biogenesis,RNA binding,structural constituent of ribosome,cytosolic large ribosomal subunit,polysomal ribosome,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005840,GO:0042254,GO:0003723,GO:0005515,GO:0003735,GO:0016020,GO:0005829,GO:0022625,GO:0042788,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","ribosome,ribosome biogenesis,RNA binding,protein binding,structural constituent of ribosome,membrane,cytosol,cytosolic large ribosomal subunit,polysomal ribosome,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["WDR46","WD repeat domain 46 [Source:HGNC Symbol;Acc:13923]","ENSG00000227057","ENSP00000363746",2,"BING4CT[1],WD40[1]","family-620","WDR46",".",".","snoRNA","putative snoRNA/rRNA","UTP7 yeast homolog","other","novel",1,1,1,".",".",".","GO:0005515","protein binding","."]
["SRP14","signal recognition particle 14kDa (homologous Alu RNA binding protein) [Source:HGNC Symbol;Acc:11299]","ENSG00000140319","ENSP00000267884",1,"SRP14[1]","family-621","SRP14",".",".","ncRNA","7SL","established RBP ","RNAbinding","experimentally validated",1,1,".",".","GO:0008312,GO:0003723,GO:0006412","7S RNA binding,RNA binding,translation","GO:0008312,GO:0030942,GO:0048500,GO:0005786,GO:0006614,GO:0003723,GO:0005737,GO:0005829,GO:0006412,GO:0042493,GO:0010467,GO:0006613,GO:0044267,GO:0045047","7S RNA binding,endoplasmic reticulum signal peptide binding,signal recognition particle,signal recognition particle, endoplasmic reticulum targeting,SRP-dependent cotranslational protein targeting to membrane,RNA binding,cytoplasm,cytosol,translation,response to drug,gene expression,cotranslational protein targeting to membrane,cellular protein metabolic process,protein targeting to ER","."]
["TFAM","transcription factor A, mitochondrial [Source:HGNC Symbol;Acc:11741]","ENSG00000108064","ENSP00000420588",2,"HMG_box[1],HMG_box_2[1]","family-622","TFAM",".",".","mRNA","putative mRNA","22658674, 22681889","candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0003700,GO:0005515,GO:0003682,GO:0008301,GO:0031072,GO:0070363,GO:0005739,GO:0005759,GO:0042645,GO:0045893,GO:0010467,GO:0006390,GO:0006261,GO:0006391,GO:0006356,GO:0033108,GO:0003677","sequence-specific DNA binding transcription factor activity,protein binding,chromatin binding,DNA binding, bending,heat shock protein binding,mitochondrial light strand promoter sense binding,mitochondrion,mitochondrial matrix,mitochondrial nucleoid,positive regulation of transcription, DNA-dependent,gene expression,transcription from mitochondrial promoter,DNA-dependent DNA replication,transcription initiation from mitochondrial promoter,regulation of transcription from RNA polymerase I promoter,mitochondrial respiratory chain complex assembly,DNA binding","."]
["CMSS1","cms1 ribosomal small subunit homolog (yeast) [Source:HGNC Symbol;Acc:28666]","ENSG00000184220","ENSP00000410396",1,"CMS1[1]","family-623","CMSS1",".",".","rRNA","putative rRNA","established RBP ","RNAbinding","novel",1,1,1,".",".",".","GO:0005524,GO:0003676,GO:0008026","ATP binding,nucleic acid binding,ATP-dependent helicase activity","."]
["XPO6","exportin 6 [Source:HGNC Symbol;Acc:19733]","ENSG00000169180","ENSP00000302790",2,"IBN_N[1],Xpo1[1]","family-624","XPO6",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".","GO:0005488,GO:0008536,GO:0005634,GO:0006886,GO:0005515,GO:0008565,GO:0005886,GO:0005737,GO:0005730,GO:0006611","binding,Ran GTPase binding,nucleus,intracellular protein transport,protein binding,protein transporter activity,plasma membrane,cytoplasm,nucleolus,protein export from nucleus","."]
["EXOSC1","exosome component 1 [Source:HGNC Symbol;Acc:17286]","ENSG00000171311","ENSP00000473303",2,"EXOSC1[1],ECR1_N[1]","family-625","EXOSC1",".",".","diverse","diverse","established RBP ",".",".",".",".",1,".","GO:0003723,GO:0000178,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","RNA binding,exosome (RNase complex),RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0000178,GO:0005634,GO:0005515,GO:0005829,GO:0005730,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006364,GO:0043928","RNA binding,exosome (RNase complex),nucleus,protein binding,cytosol,nucleolus,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA processing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["ZNF106","zinc finger protein 106 [Source:HGNC Symbol;Acc:12886]","ENSG00000103994","ENSP00000454882",1,"zf-C2H2_jaz[1]","family-626","BTRC,WDR86,ZNF106,FBXW11,FBXW2,FBXW7","BTRC","WDR86[15,24],ZNF106[20,7],FBXW11[76,84],FBXW2[16,21],FBXW7[26,22]","unknown","unknown","established RBP ",".","novel",".",1,".",".",".",".","GO:0046872,GO:0017124,GO:0001515,GO:0016020,GO:0005829,GO:0008286,GO:0005515,GO:0005730","metal ion binding,SH3 domain binding,opioid peptide activity,membrane,cytosol,insulin receptor signaling pathway,protein binding,nucleolus","."]
["UTP14A","UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) [Source:HGNC Symbol;Acc:10665]","ENSG00000156697","ENSP00000413187",1,"Utp14[1]","family-627","UTP14A,UTP14C","UTP14A","UTP14C[89,90]","snoRNA","snoRNA/rRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0006364","rRNA processing","GO:0005515,GO:0005730,GO:0032040,GO:0006364","protein binding,nucleolus,small-subunit processome,rRNA processing","."]
["UTP14C","UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) [Source:HGNC Symbol;Acc:20321]","ENSG00000253797","ENSP00000428619",1,"Utp14[1]","family-627","UTP14A,UTP14C","UTP14A","UTP14C[89,90]","snoRNA","snoRNA/rRNA","established RBP ",".",".",".",".",1,".","GO:0006364","rRNA processing","GO:0005730,GO:0032040,GO:0030154,GO:0007275,GO:0007283,GO:0006364,GO:0007126","nucleolus,small-subunit processome,cell differentiation,multicellular organismal development,spermatogenesis,rRNA processing,meiosis","."]
["TRUB1","TruB pseudouridine (psi) synthase homolog 1 (E. coli) [Source:HGNC Symbol;Acc:16060]","ENSG00000165832","ENSP00000298746",1,"TruB_N[1]","family-628","TRUB1,TRUB2","TRUB1","TRUB2[26,27]","tRNA","putative tRNA/rRNA","by domain",".",".",".",".",".",".","GO:0003723,GO:0008033,GO:0006396,GO:0009451","RNA binding,tRNA processing,RNA processing,RNA modification","GO:0003723,GO:0009982,GO:0008033,GO:0006396,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,tRNA processing,RNA processing,pseudouridine synthesis,RNA modification","."]
["TRUB2","TruB pseudouridine (psi) synthase homolog 2 (E. coli) [Source:HGNC Symbol;Acc:17170]","ENSG00000167112","ENSP00000438084",1,"TruB_N[1]","family-628","TRUB1,TRUB2","TRUB1","TRUB2[26,27]","tRNA","putative tRNA/rRNA","by domain","RNAmod","RNAbinding",1,1,".",".","GO:0003723,GO:0006396,GO:0009451,GO:0008033","RNA binding,RNA processing,RNA modification,tRNA processing","GO:0003723,GO:0009982,GO:0006396,GO:0001522,GO:0009451,GO:0008033","RNA binding,pseudouridine synthase activity,RNA processing,pseudouridine synthesis,RNA modification,tRNA processing","."]
["PRIM1","primase, DNA, polypeptide 1 (49kDa) [Source:HGNC Symbol;Acc:9369]","ENSG00000198056","ENSP00000350491",1,"DNA_primase_S[1]","family-629","PRIM1",".",".","diverse","RNA/DNA","DNA primase is, in fact, a type of RNA polymerase which creates an RNA primer",".",".",".",".",".",".","GO:0006269","DNA replication, synthesis of RNA primer","GO:0003896,GO:1990077,GO:0006269,GO:0005515,GO:0046872,GO:0005654,GO:0000278,GO:0000723,GO:0006270,GO:0000082,GO:0006271,GO:0000722,GO:0032201","DNA primase activity,primosome complex,DNA replication, synthesis of RNA primer,protein binding,metal ion binding,nucleoplasm,mitotic cell cycle,telomere maintenance,DNA replication initiation,G1/S transition of mitotic cell cycle,DNA strand elongation involved in DNA replication,telomere maintenance via recombination,telomere maintenance via semi-conservative replication","."]
["PTCD3","pentatricopeptide repeat domain 3 [Source:HGNC Symbol;Acc:24717] [Type: protein coding Ensembl/Havana merge]","ENSG00000132300","ENSP00000254630",2,"PPR_2[1],PPR_3[1]","family-63","PTCD3",".",".","mRNA","putative mRNA",19427859,"candidate mRNA binder","novel",1,1,1,".","GO:0019843,GO:0043024,GO:0006417,GO:0032543","rRNA binding,ribosomal small subunit binding,regulation of translation,mitochondrial translation","GO:0019843,GO:0043024,GO:0005739,GO:0006417,GO:0032543","rRNA binding,ribosomal small subunit binding,mitochondrion,regulation of translation,mitochondrial translation","."]
["HNRNPA0","heterogeneous nuclear ribonucleoprotein A0 [Source:HGNC Symbol;Acc:5030]","ENSG00000177733","ENSP00000316042",2,"RRM_1[1],RRM_6[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0017091,GO:0003723,GO:0030529,GO:0070935,GO:0006397,GO:0008380,GO:0000398","AU-rich element binding,RNA binding,ribonucleoprotein complex,3'-UTR-mediated mRNA stabilization,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","GO:0017091,GO:0000166,GO:0003723,GO:0003676,GO:0019901,GO:0005634,GO:0005654,GO:0030529,GO:0032496,GO:0006954,GO:0070935,GO:0010467,GO:0006397,GO:0008380,GO:0000398","AU-rich element binding,nucleotide binding,RNA binding,nucleic acid binding,protein kinase binding,nucleus,nucleoplasm,ribonucleoprotein complex,response to lipopolysaccharide,inflammatory response,3'-UTR-mediated mRNA stabilization,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","."]
["HNRNPA1","heterogeneous nuclear ribonucleoprotein A1 [Source:HGNC Symbol;Acc:5031]","ENSG00000135486","ENSP00000333504",3,"HnRNPA1[1],RRM_1[2]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0000380,GO:0003723,GO:0003727,GO:0005681,GO:0030529,GO:0071013,GO:0006397,GO:0008380,GO:0051028,GO:0000398,GO:0006405","alternative mRNA splicing, via spliceosome,RNA binding,single-stranded RNA binding,spliceosomal complex,ribonucleoprotein complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA transport,mRNA splicing, via spliceosome,RNA export from nucleus","GO:0000166,GO:0003676,GO:0005634,GO:0000380,GO:0005737,GO:0005730,GO:0045111,GO:0003723,GO:0005515,GO:0003727,GO:0003697,GO:0005654,GO:0005681,GO:0030529,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0051028,GO:0000398,GO:0019048,GO:0051168,GO:0006405,GO:0051170","nucleotide binding,nucleic acid binding,nucleus,alternative mRNA splicing, via spliceosome,cytoplasm,nucleolus,intermediate filament cytoskeleton,RNA binding,protein binding,single-stranded RNA binding,single-stranded DNA binding,nucleoplasm,spliceosomal complex,ribonucleoprotein complex,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA transport,mRNA splicing, via spliceosome,modulation by virus of host morphology or physiology,nuclear export,RNA export from nucleus,nuclear import","."]
["HNRNPA1L2","heterogeneous nuclear ribonucleoprotein A1-like 2 [Source:HGNC Symbol;Acc:27067]","ENSG00000139675","ENSP00000350090",3,"HnRNPA1[1],RRM_1[2]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380,GO:0051028","RNA binding,spliceosomal complex,mRNA processing,RNA splicing,mRNA transport","GO:0000166,GO:0003723,GO:0003676,GO:0005737,GO:0005681,GO:0006397,GO:0008380,GO:0051028","nucleotide binding,RNA binding,nucleic acid binding,cytoplasm,spliceosomal complex,mRNA processing,RNA splicing,mRNA transport","."]
["HNRNPA2B1","heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:5033]","ENSG00000122566","ENSP00000346694",2,"RRM_1[1],RRM_6[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0097157,GO:0005681,GO:0030529,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0048025,GO:0050658","RNA binding,pre-mRNA intronic binding,spliceosomal complex,ribonucleoprotein complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome,RNA transport","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0043047,GO:0097157,GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0005681,GO:0030529,GO:0071013,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0048025,GO:0050658","nucleotide binding,RNA binding,protein binding,nucleic acid binding,single-stranded telomeric DNA binding,pre-mRNA intronic binding,nucleus,cytoplasm,nucleolus,nucleoplasm,spliceosomal complex,ribonucleoprotein complex,catalytic step 2 spliceosome,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome,RNA transport","."]
["HNRNPA3","heterogeneous nuclear ribonucleoprotein A3 [Source:HGNC Symbol;Acc:24941]","ENSG00000170144","ENSP00000408487",2,"RRM_1[1],RRM_6[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0071013,GO:0008380,GO:0000398","RNA binding,ribonucleoprotein complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005730,GO:0005654,GO:0030529,GO:0071013,GO:0010467,GO:0008380,GO:0000398","nucleotide binding,RNA binding,nucleic acid binding,nucleus,nucleolus,nucleoplasm,ribonucleoprotein complex,catalytic step 2 spliceosome,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["HNRNPAB","heterogeneous nuclear ribonucleoprotein A/B [Source:HGNC Symbol;Acc:5034]","ENSG00000197451","ENSP00000425031",3,"RRM_1[2],CBFNT[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0030529","RNA binding,mRNA binding,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0003700,GO:0003676,GO:0043565,GO:0003729,GO:0005634,GO:0005737,GO:0030529,GO:0045893,GO:0001837","nucleotide binding,RNA binding,sequence-specific DNA binding transcription factor activity,nucleic acid binding,sequence-specific DNA binding,mRNA binding,nucleus,cytoplasm,ribonucleoprotein complex,positive regulation of transcription, DNA-dependent,epithelial to mesenchymal transition","."]
["HNRNPD","heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) [Source:HGNC Symbol;Acc:5036]","ENSG00000138668","ENSP00000439380",3,"RRM_1[2],CBFNT[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0043488,GO:0030529,GO:0003723,GO:0016070,GO:0016071,GO:0008380,GO:0000398,GO:0006396,GO:0006401","regulation of mRNA stability,ribonucleoprotein complex,RNA binding,RNA metabolic process,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA catabolic process","GO:0000166,GO:0003676,GO:0005634,GO:0043488,GO:0030529,GO:0019013,GO:0003723,GO:0005515,GO:0042162,GO:0005829,GO:0005654,GO:0006351,GO:0045893,GO:0006355,GO:0010467,GO:0016070,GO:0016071,GO:0008380,GO:0000398,GO:0006396,GO:0006401","nucleotide binding,nucleic acid binding,nucleus,regulation of mRNA stability,ribonucleoprotein complex,viral nucleocapsid,RNA binding,protein binding,telomeric DNA binding,cytosol,nucleoplasm,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,mRNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA catabolic process","."]
["HNRNPDL","heterogeneous nuclear ribonucleoprotein D-like [Source:HGNC Symbol;Acc:5037]","ENSG00000152795","ENSP00000295470",3,"RRM_1[2],CBFNT[1]","family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","HNRNPA0","HNRNPA3[56,46],HNRNPA1L2[49,47],HNRNPA1[51,42],HNRNPA2B1[52,45],HNRNPD[31,26],HNRNPAB[30,27],HNRNPDL[32,23]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008143,GO:0034046,GO:0005681,GO:0006396","RNA binding,poly(A) RNA binding,poly(G) RNA binding,spliceosomal complex,RNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0008143,GO:0034046,GO:0005634,GO:0005737,GO:0005681,GO:0006351,GO:0006355,GO:0006396,GO:0010468","nucleotide binding,RNA binding,nucleic acid binding,DNA binding,double-stranded DNA binding,single-stranded DNA binding,poly(A) RNA binding,poly(G) RNA binding,nucleus,cytoplasm,spliceosomal complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,RNA processing,regulation of gene expression","."]
["RANBP2","RAN binding protein 2 [Source:HGNC Symbol;Acc:9848]","ENSG00000153201","ENSP00000283195",16,"TPR_1[1],IR1-M[2],zf-RanBP[8],Ran_BP1[4],Pro_isomerase[1]","family-631","RANBP2,RGPD6,RGPD5,RGPD3,RGPD8,RGPD1,RGPD4,RGPD2","RANBP2","RGPD6[50,91],RGPD5[50,91],RGPD3[50,92],RGPD8[50,91],RGPD1[49,90],RGPD4[50,92],RGPD2[49,91]","mRNA","putative mRNA",23630457,".",".",".",".",".",".","GO:0003723,GO:0051028","RNA binding,mRNA transport","GO:0005515,GO:0003723,GO:0008270,GO:0016874,GO:0003755,GO:0008536,GO:0005739,GO:0005829,GO:0031965,GO:0005643,GO:0042405,GO:0044615,GO:0033132,GO:0090526,GO:0055085,GO:0044281,GO:0006457,GO:0000278,GO:0016032,GO:0005975,GO:0051028,GO:0016925,GO:0006606,GO:0019221,GO:0046907,GO:0010827,GO:0015758,GO:0007077,GO:0008645","protein binding,RNA binding,zinc ion binding,ligase activity,peptidyl-prolyl cis-trans isomerase activity,Ran GTPase binding,mitochondrion,cytosol,nuclear membrane,nuclear pore,nuclear inclusion body,nuclear pore nuclear basket,negative regulation of glucokinase activity,regulation of gluconeogenesis involved in cellular glucose homeostasis,transmembrane transport,small molecule metabolic process,protein folding,mitotic cell cycle,viral process,carbohydrate metabolic process,mRNA transport,protein sumoylation,protein import into nucleus,cytokine-mediated signaling pathway,intracellular transport,regulation of glucose transport,glucose transport,mitotic nuclear envelope disassembly,hexose transport"," ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, SUSCEPTIBILITY TO, 3; IIAE3"]
["RPL7","ribosomal protein L7 [Source:HGNC Symbol;Acc:10363]","ENSG00000147604","ENSP00000401300",2,"Ribosomal_L30[1],Ribosomal_L30_N[1]","family-632","RPL7,RPL7L1","RPL7","RPL7L1[43,43]","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0022625,GO:0003723,GO:0003735,GO:0003729,GO:0030529,GO:0006412,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","cytosolic large ribosomal subunit,RNA binding,structural constituent of ribosome,mRNA binding,ribonucleoprotein complex,translation,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0022625,GO:0003723,GO:0005515,GO:0042803,GO:0003677,GO:0003735,GO:0003729,GO:0005829,GO:0030529,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","cytosolic large ribosomal subunit,RNA binding,protein binding,protein homodimerization activity,DNA binding,structural constituent of ribosome,mRNA binding,cytosol,ribonucleoprotein complex,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL7L1","ribosomal protein L7-like 1 [Source:HGNC Symbol;Acc:21370]","ENSG00000146223","ENSP00000445293",2,"Ribosomal_L30[1],Ribosomal_L30_N[1]","family-632","RPL7,RPL7L1","RPL7","RPL7L1[43,43]","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0005840","ribosome","GO:0005840","ribosome","."]
["RNASE13","ribonuclease, RNase A family, 13 (non-active) [Source:HGNC Symbol;Acc:25285]","ENSG00000206150","ENSP00000372410",1,"RnaseA[1]","family-633","RNASE13",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0003676,GO:0016892,GO:0005576","nucleic acid binding,endoribonuclease activity, producing 3'-phosphomonoesters,extracellular region","."]
["RPS6","ribosomal protein S6 [Source:HGNC Symbol;Acc:10429]","ENSG00000137154","ENSP00000369757",1,"Ribosomal_S6e[1]","family-634","RPS6",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0000028,GO:0030529,GO:0015935,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,ribosomal small subunit assembly,ribonucleoprotein complex,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005737,GO:0022627,GO:0000028,GO:0042593,GO:0005515,GO:0019901,GO:0005634,GO:0005829,GO:0005730,GO:0030529,GO:0015935,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0008286,GO:0006364,GO:0043065,GO:0044267,GO:0031929,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","structural constituent of ribosome,intracellular,ribosome,translation,cytoplasm,cytosolic small ribosomal subunit,ribosomal small subunit assembly,glucose homeostasis,protein binding,protein kinase binding,nucleus,cytosol,nucleolus,ribonucleoprotein complex,small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,insulin receptor signaling pathway,rRNA processing,positive regulation of apoptotic process,cellular protein metabolic process,TOR signaling,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis","."]
["MRPL3","mitochondrial ribosomal protein L3 [Source:HGNC Symbol;Acc:10379]","ENSG00000114686","ENSP00000398536",1,"Ribosomal_L3[1]","family-635","MRPL3",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005762","structural constituent of ribosome,ribosome,translation,RNA binding,mitochondrial large ribosomal subunit","GO:0005739,GO:0003735,GO:0005840,GO:0006412,GO:0005622,GO:0003723,GO:0005762","mitochondrion,structural constituent of ribosome,ribosome,translation,intracellular,RNA binding,mitochondrial large ribosomal subunit"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 9; COXPD9"]
["DDX28","DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Source:HGNC Symbol;Acc:17330]","ENSG00000182810","ENSP00000332340",2,"Helicase_C[1],DEAD[1]","family-636","DDX28,DDX47","DDX28","DDX47[26,31]","rRNA","putative rRNA","RRP3 yeast homolog","helicase","RNAbinding",1,1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005739,GO:0005634,GO:0005737,GO:0005730,GO:0042645","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,mitochondrion,nucleus,cytoplasm,nucleolus,mitochondrial nucleoid","."]
["DDX47","DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 [Source:HGNC Symbol;Acc:18682]","ENSG00000213782","ENSP00000319578",2,"Helicase_C[1],DEAD[1]","family-636","DDX28,DDX47","DDX28","DDX47[26,31]","rRNA","putative rRNA","RRP3 yeast homolog","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0006397,GO:0008380,GO:0006364","RNA binding,mRNA processing,RNA splicing,rRNA processing","GO:0005524,GO:0003676,GO:0008026,GO:0003723,GO:0005515,GO:0003677,GO:0016787,GO:0004386,GO:0005730,GO:0006397,GO:0008380,GO:0006364,GO:0008625","ATP binding,nucleic acid binding,ATP-dependent helicase activity,RNA binding,protein binding,DNA binding,hydrolase activity,helicase activity,nucleolus,mRNA processing,RNA splicing,rRNA processing,extrinsic apoptotic signaling pathway via death domain receptors","."]
["RNASEH2C","ribonuclease H2, subunit C [Source:HGNC Symbol;Acc:24116]","ENSG00000172922","ENSP00000432897",1,"RNase_H2_suC[1]","family-637","RNASEH2C",".",".","diverse","RNA/DNA","established RBP ",".",".",".",".",".",".","GO:0032299,GO:0006401","ribonuclease H2 complex,RNA catabolic process","GO:0005634,GO:0032299,GO:0006401","nucleus,ribonuclease H2 complex,RNA catabolic process"," AICARDI-GOUTIERES SYNDROME 3; AGS3"]
["TFB2M","transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:18559]","ENSG00000162851","ENSP00000442426",1,"RrnaAD[1]","family-638","TFB2M",".",".","rRNA","putative rRNA",17031457,"RNAmod",".",".",1,".",".","GO:0000179,GO:0008649,GO:0000154,GO:0003723,GO:0031167","rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,rRNA modification,RNA binding,rRNA methylation","GO:0000179,GO:0008649,GO:0000154,GO:0003723,GO:0003712,GO:0005739,GO:0005759,GO:0042645,GO:0045893,GO:0006355,GO:0010467,GO:0006390,GO:0006391,GO:0031167","rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,rRNA modification,RNA binding,transcription cofactor activity,mitochondrion,mitochondrial matrix,mitochondrial nucleoid,positive regulation of transcription, DNA-dependent,regulation of transcription, DNA-dependent,gene expression,transcription from mitochondrial promoter,transcription initiation from mitochondrial promoter,rRNA methylation","."]
["TEP1","telomerase-associated protein 1 [Source:HGNC Symbol;Acc:11726]","ENSG00000129566","ENSP00000452574",15,"NACHT[1],TROVE[1],TEP1_N[4],WD40[8],DUF4062[1]","family-639","TEP1",".",".","ncRNA","teloRNA/vtRNA","This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. [provided by RefSeq, Jul 2008]",".",".",".",".",".",1,"GO:0003723,GO:0030529,GO:0003720,GO:0005697","RNA binding,ribonucleoprotein complex,telomerase activity,telomerase holoenzyme complex","GO:0005515,GO:0003723,GO:0005524,GO:0030529,GO:0003720,GO:0005737,GO:0000781,GO:0016363,GO:0005697,GO:0000722","protein binding,RNA binding,ATP binding,ribonucleoprotein complex,telomerase activity,cytoplasm,chromosome, telomeric region,nuclear matrix,telomerase holoenzyme complex,telomere maintenance via recombination","."]
["NOC4L","nucleolar complex associated 4 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28461]","ENSG00000184967","ENSP00000443336",1,"CBF[1]","family-64","NOC4L",".",".","rRNA","putative rRNA","NOC4 homolog yeast",".","RNArelated",".",1,".",".","GO:0042254,GO:0006364","ribosome biogenesis,rRNA processing","GO:0042254,GO:0005488,GO:0005515,GO:0016021,GO:0005730,GO:0031965,GO:0006364","ribosome biogenesis,binding,protein binding,integral to membrane,nucleolus,nuclear membrane,rRNA processing","."]
["CPSF1","cleavage and polyadenylation specific factor 1, 160kDa [Source:HGNC Symbol;Acc:2324]","ENSG00000071894","ENSP00000339353",2,"MMS1_N[1],CPSF_A[1]","family-640","CPSF1",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003730,GO:0005847,GO:0008380,GO:0000398,GO:0006379,GO:0006406,GO:0031124,GO:0006378","mRNA 3'-UTR binding,mRNA cleavage and polyadenylation specificity factor complex,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA export from nucleus,mRNA 3'-end processing,mRNA polyadenylation","GO:0003676,GO:0005634,GO:0005515,GO:0003730,GO:0005654,GO:0005847,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006379,GO:0006406,GO:0031124,GO:0006378,GO:0006369","nucleic acid binding,nucleus,protein binding,mRNA 3'-UTR binding,nucleoplasm,mRNA cleavage and polyadenylation specificity factor complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA export from nucleus,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription","."]
["DDX1","DEAD (Asp-Glu-Ala-Asp) box helicase 1 [Source:HGNC Symbol;Acc:2734]","ENSG00000079785","ENSP00000370745",2,"Helicase_C[1],DEAD[1]","family-641","DDX3X,DDX3Y,DDX1,DDX4","DDX3X","DDX3Y[92,92],DDX1[21,18],DDX4[40,37]","mRNA","mRNA","established RBP ","helicase","experimentally validated",1,1,1,".","GO:0004527,GO:0003725,GO:0003724,GO:0008143,GO:0033677,GO:0030529,GO:0010494,GO:0072669,GO:0043330,GO:0006446,GO:0000245","exonuclease activity,double-stranded RNA binding,RNA helicase activity,poly(A) RNA binding,DNA/RNA helicase activity,ribonucleoprotein complex,cytoplasmic stress granule,tRNA-splicing ligase complex,response to exogenous dsRNA,regulation of translational initiation,spliceosomal complex assembly","GO:0005515,GO:0005524,GO:0003676,GO:0004527,GO:0003677,GO:0003725,GO:0008026,GO:0003682,GO:0004386,GO:0004518,GO:0003712,GO:0003724,GO:0008143,GO:0033677,GO:0005634,GO:0005737,GO:0030529,GO:0010494,GO:0072669,GO:0071920,GO:0006351,GO:0007275,GO:0009615,GO:0043330,GO:0006355,GO:0006446,GO:0006302,GO:0000245,GO:0032508,GO:0090305","protein binding,ATP binding,nucleic acid binding,exonuclease activity,DNA binding,double-stranded RNA binding,ATP-dependent helicase activity,chromatin binding,helicase activity,nuclease activity,transcription cofactor activity,RNA helicase activity,poly(A) RNA binding,DNA/RNA helicase activity,nucleus,cytoplasm,ribonucleoprotein complex,cytoplasmic stress granule,tRNA-splicing ligase complex,cleavage body,transcription, DNA-templated,multicellular organismal development,response to virus,response to exogenous dsRNA,regulation of transcription, DNA-dependent,regulation of translational initiation,double-strand break repair,spliceosomal complex assembly,DNA duplex unwinding,nucleic acid phosphodiester bond hydrolysis","."]
["DDX3X","DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked [Source:HGNC Symbol;Acc:2745]","ENSG00000215301","ENSP00000392494",2,"Helicase_C[1],DEAD[1]","family-641","DDX3X,DDX3Y,DDX1,DDX4","DDX3X","DDX3Y[92,92],DDX1[21,18],DDX4[40,37]","mRNA","mRNA","established RBP ","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0031369,GO:0008143,GO:0004004,GO:0048027,GO:0008190,GO:0035613,GO:0043024,GO:0022627,GO:0005852,GO:0010494,GO:0045727,GO:0042256,GO:0010501,GO:0045948","RNA binding,translation initiation factor binding,poly(A) RNA binding,ATP-dependent RNA helicase activity,mRNA 5'-UTR binding,eukaryotic initiation factor 4E binding,RNA stem-loop binding,ribosomal small subunit binding,cytosolic small ribosomal subunit,eukaryotic translation initiation factor 3 complex,cytoplasmic stress granule,positive regulation of translation,mature ribosome assembly,RNA secondary structure unwinding,positive regulation of translational initiation","GO:0004386,GO:0005737,GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0004003,GO:0016887,GO:0008134,GO:0031369,GO:0008143,GO:0004004,GO:0048027,GO:0008190,GO:0035613,GO:0043024,GO:0005634,GO:0022627,GO:0005741,GO:0005852,GO:0010494,GO:0016607,GO:0006351,GO:0045944,GO:0045087,GO:0043066,GO:0030308,GO:0009615,GO:0032728,GO:2001243,GO:0035556,GO:0006200,GO:0043065,GO:0043154,GO:0045727,GO:0030307,GO:0097193,GO:0034063,GO:0043280,GO:0042256,GO:0017148,GO:0007059,GO:0008625,GO:0019048,GO:0010501,GO:0031333,GO:0045948,GO:0071243,GO:0071470,GO:0071651,GO:1900087","helicase activity,cytoplasm,RNA binding,protein binding,ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,ATP-dependent DNA helicase activity,ATPase activity,transcription factor binding,translation initiation factor binding,poly(A) RNA binding,ATP-dependent RNA helicase activity,mRNA 5'-UTR binding,eukaryotic initiation factor 4E binding,RNA stem-loop binding,ribosomal small subunit binding,nucleus,cytosolic small ribosomal subunit,mitochondrial outer membrane,eukaryotic translation initiation factor 3 complex,cytoplasmic stress granule,nuclear speck,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,innate immune response,negative regulation of apoptotic process,negative regulation of cell growth,response to virus,positive regulation of interferon-beta production,negative regulation of intrinsic apoptotic signaling pathway,intracellular signal transduction,ATP catabolic process,positive regulation of apoptotic process,negative regulation of cysteine-type endopeptidase activity involved in apoptotic process,positive regulation of translation,positive regulation of cell growth,intrinsic apoptotic signaling pathway,stress granule assembly,positive regulation of cysteine-type endopeptidase activity involved in apoptotic process,mature ribosome assembly,negative regulation of translation,chromosome segregation,extrinsic apoptotic signaling pathway via death domain receptors,modulation by virus of host morphology or physiology,RNA secondary structure unwinding,negative regulation of protein complex assembly,positive regulation of translational initiation,cellular response to arsenic-containing substance,cellular response to osmotic stress,positive regulation of chemokine (C-C motif) ligand 5 production,positive regulation of G1/S transition of mitotic cell cycle","."]
["DDX3Y","DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [Source:HGNC Symbol;Acc:2699]","ENSG00000067048","ENSP00000353284",2,"Helicase_C[1],DEAD[1]","family-641","DDX3X,DDX3Y,DDX1,DDX4","DDX3X","DDX3Y[92,92],DDX1[21,18],DDX4[40,37]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0005524,GO:0003676,GO:0008026,GO:0005737,GO:0003723,GO:0003677,GO:0004386,GO:0005634","ATP binding,nucleic acid binding,ATP-dependent helicase activity,cytoplasm,RNA binding,DNA binding,helicase activity,nucleus","."]
["DDX4","DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 [Source:HGNC Symbol;Acc:18700]","ENSG00000152670","ENSP00000425359",2,"Helicase_C[1],DEAD[1]","family-641","DDX3X,DDX3Y,DDX1,DDX4","DDX3X","DDX3Y[92,92],DDX1[21,18],DDX4[40,37]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0071546,GO:0071547,GO:0030529","pi-body,piP-body,ribonucleoprotein complex","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634,GO:0005737,GO:0048471,GO:0071546,GO:0033391,GO:0071547,GO:0007275,GO:0007283,GO:0007141,GO:0032880,GO:0030317,GO:0030529","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus,cytoplasm,perinuclear region of cytoplasm,pi-body,chromatoid body,piP-body,multicellular organismal development,spermatogenesis,male meiosis I,regulation of protein localization,sperm motility,ribonucleoprotein complex","."]
["NOP56","NOP56 ribonucleoprotein [Source:HGNC Symbol;Acc:15911]","ENSG00000101361","ENSP00000370589",3,"NOP5NT[1],Nop[1],NOSIC[1]","family-642","NOP56",".",".","snoRNA","snoRNA",19331828,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0030515,GO:0005732,GO:0031428,GO:0070761,GO:0006364","RNA binding,snoRNA binding,small nucleolar ribonucleoprotein complex,box C/D snoRNP complex,pre-snoRNP complex,rRNA processing","GO:0003723,GO:0005515,GO:0030515,GO:0005737,GO:0005730,GO:0005732,GO:0031428,GO:0070761,GO:0006364,GO:0008219","RNA binding,protein binding,snoRNA binding,cytoplasm,nucleolus,small nucleolar ribonucleoprotein complex,box C/D snoRNP complex,pre-snoRNP complex,rRNA processing,cell death"," SPINOCEREBELLAR ATAXIA 36; SCA36"]
["RPS20","ribosomal protein S20 [Source:HGNC Symbol;Acc:10405]","ENSG00000008988","ENSP00000427860",1,"Ribosomal_S10[1]","family-643","RPS20",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0015935,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,translation,small ribosomal subunit,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0015935,GO:0005515,GO:0005737,GO:0005829,GO:0022627,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,ribosome,translation,small ribosomal subunit,protein binding,cytoplasm,cytosol,cytosolic small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["MPHOSPH10","M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [Source:HGNC Symbol;Acc:7213]","ENSG00000124383","ENSP00000244230",1,"Mpp10[1]","family-644","MPHOSPH10",".",".","snoRNA","snoRNA",9478208,"candidate mRNA binder","RNArelated",1,1,1,".","GO:0030529,GO:0005732,GO:0008380,GO:0006364,GO:0006396,GO:0000375","ribonucleoprotein complex,small nucleolar ribonucleoprotein complex,RNA splicing,rRNA processing,RNA processing,RNA splicing, via transesterification reactions","GO:0005515,GO:0005634,GO:0005694,GO:0005730,GO:0030529,GO:0005732,GO:0008380,GO:0006364,GO:0006396,GO:0010923,GO:0000375","protein binding,nucleus,chromosome,nucleolus,ribonucleoprotein complex,small nucleolar ribonucleoprotein complex,RNA splicing,rRNA processing,RNA processing,negative regulation of phosphatase activity,RNA splicing, via transesterification reactions","."]
["MRM1","mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26202]","ENSG00000129282","ENSP00000250156",2,"SpoU_methylase[1],SpoU_sub_bind[1]","family-645","MRM1",".",".","rRNA","rRNA",24036117,"RNAmod","RNAbinding",1,1,".",".","GO:0003723,GO:0008173,GO:0006396","RNA binding,RNA methyltransferase activity,RNA processing","GO:0008168,GO:0003723,GO:0008173,GO:0005739,GO:0006396","methyltransferase activity,RNA binding,RNA methyltransferase activity,mitochondrion,RNA processing","."]
["DXO","dom-3 homolog Z (C. elegans) [Source:HGNC Symbol;Acc:2992]","ENSG00000236765","ENSP00000391123",1,"RAI1[1]","family-646","DXO",".",".","diverse","diverse","RAI1; DOM3L; DOM3Z",".",".",".",".",".",".","GO:0003729,GO:0008409,GO:0034353,GO:0006402,GO:0050779,GO:0071028","mRNA binding,5'-3' exonuclease activity,RNA pyrophosphohydrolase activity,mRNA catabolic process,RNA destabilization,nuclear mRNA surveillance","GO:0000166,GO:0000287,GO:0003729,GO:0008409,GO:0034353,GO:0005634,GO:0008152,GO:0006402,GO:0050779,GO:0071028,GO:0090305","nucleotide binding,magnesium ion binding,mRNA binding,5'-3' exonuclease activity,RNA pyrophosphohydrolase activity,nucleus,metabolic process,mRNA catabolic process,RNA destabilization,nuclear mRNA surveillance,nucleic acid phosphodiester bond hydrolysis","."]
["DENR","density-regulated protein [Source:HGNC Symbol;Acc:2769]","ENSG00000139726","ENSP00000413661",1,"SUI1[1]","family-647","DENR",".",".","mRNA","putative mRNA","This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003743,GO:0006413","translation initiation factor activity,translational initiation","GO:0003743,GO:0006413,GO:0005515","translation initiation factor activity,translational initiation,protein binding","."]
["RPL21","ribosomal protein L21 [Source:HGNC Symbol;Acc:10313]","ENSG00000122026","ENSP00000346027",1,"Ribosomal_L21e[1]","family-648","RPL21",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS10","ribosomal protein S10 [Source:HGNC Symbol;Acc:10383]","ENSG00000124614","ENSP00000347271",1,"S10_plectin[1]","family-649","RPS10",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0022627,GO:0005840,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","cytosolic small ribosomal subunit,ribosome,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0005515,GO:0005829,GO:0005730,GO:0022627,GO:0005840,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","protein binding,cytosol,nucleolus,cytosolic small ribosomal subunit,ribosome,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription"," DIAMOND-BLACKFAN ANEMIA 9; DBA9"]
["NAT10","N-acetyltransferase 10 (GCN5-related) [Source:HGNC Symbol;Acc:29830]","ENSG00000135372","ENSP00000433011",4,"tRNA_bind_2[1],Helicase_RecD[1],GNAT_acetyltr_2[1],DUF1726[1]","family-65","NAT10",".",".","rRNA","putative rRNA"," KRE33 yeast homolog","metabolicEnz","novel",1,1,1,".",".",".","GO:0008080,GO:0005524,GO:0005634,GO:0005730","N-acetyltransferase activity,ATP binding,nucleus,nucleolus","."]
["UTP18","UTP18 small subunit (SSU) processome component homolog (yeast) [Source:HGNC Symbol;Acc:24274]","ENSG00000011260","ENSP00000225298",1,"Cytochrom_D1[1]","family-650","UTP18",".",".","snoRNA","snoRNA/rRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0006364","rRNA processing","GO:0005515,GO:0005634,GO:0005730,GO:0006364","protein binding,nucleus,nucleolus,rRNA processing","."]
["NOL12","nucleolar protein 12 [Source:HGNC Symbol;Acc:28585]","ENSG00000100101","ENSP00000352021",1,"Nop25[1]","family-651","NOL12",".",".","rRNA","rRNA",16515785,"RNAbinding","novel",1,1,".",".","GO:0019843","rRNA binding","GO:0019843,GO:0005730","rRNA binding,nucleolus","."]
["DDX31","DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 [Source:HGNC Symbol;Acc:16715]","ENSG00000125485","ENSP00000387730",3,"DUF4217[1],Helicase_C[1],DEAD[1]","family-652","DDX31",".",".","rRNA","putative rRNA","yeast homolog DBP7","helicase","RNAbinding",1,1,1,".","GO:0003723","RNA binding","GO:0004386,GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0005730","helicase activity,RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,nucleolus","."]
["ABCF1","ATP-binding cassette, sub-family F (GCN20), member 1 [Source:HGNC Symbol;Acc:70]","ENSG00000225989","ENSP00000412553",3,"ABC_tran_2[1],ABC_tran[2]","family-653","ABCF1,ABCF3","ABCF1","ABCF3[30,36]","mRNA","mRNA",19570978,"RNAbinding","RNArelated",1,1,1,".","GO:0005840,GO:0043022,GO:0008135,GO:0008494,GO:0042788,GO:0006412,GO:0045727,GO:0006413","ribosome,ribosome binding,translation factor activity, nucleic acid binding,translation activator activity,polysomal ribosome,translation,positive regulation of translation,translational initiation","GO:0005524,GO:0016887,GO:0005840,GO:0000166,GO:0005515,GO:0017111,GO:0043022,GO:0008135,GO:0008494,GO:0005737,GO:0005654,GO:0005635,GO:0042788,GO:0006954,GO:0006412,GO:0045727,GO:0006413","ATP binding,ATPase activity,ribosome,nucleotide binding,protein binding,nucleoside-triphosphatase activity,ribosome binding,translation factor activity, nucleic acid binding,translation activator activity,cytoplasm,nucleoplasm,nuclear envelope,polysomal ribosome,inflammatory response,translation,positive regulation of translation,translational initiation","."]
["DNMT1","DNA (cytosine-5-)-methyltransferase 1 [Source:HGNC Symbol;Acc:2976]","ENSG00000130816","ENSP00000352516",6,"DNA_methylase[1],BAH[2],DNMT1-RFD[1],DMAP_binding[1],zf-CXXC[1]","family-654","DNMT1",".",".","ncRNA","lincRNA","24107992, 24481530",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0008270,GO:0003677,GO:0003682,GO:0008168,GO:0008134,GO:0003886,GO:0008327,GO:0005634,GO:0005721,GO:0005657,GO:0045892,GO:0042127,GO:0006306,GO:0010216,GO:0071230,GO:0016458,GO:0090116,GO:0005515,GO:0009008,GO:0000792,GO:0000122,GO:0010468,GO:0006351,GO:0010628,GO:0016568,GO:0051571,GO:0051573","RNA binding,zinc ion binding,DNA binding,chromatin binding,methyltransferase activity,transcription factor binding,DNA (cytosine-5-)-methyltransferase activity,methyl-CpG binding,nucleus,centromeric heterochromatin,replication fork,negative regulation of transcription, DNA-dependent,regulation of cell proliferation,DNA methylation,maintenance of DNA methylation,cellular response to amino acid stimulus,gene silencing,C-5 methylation of cytosine,protein binding,DNA-methyltransferase activity,heterochromatin,negative regulation of transcription from RNA polymerase II promoter,regulation of gene expression,transcription, DNA-templated,positive regulation of gene expression,chromatin modification,positive regulation of histone H3-K4 methylation,negative regulation of histone H3-K9 methylation"," CEREBELLAR ATAXIA, DEAFNESS, AND NARCOLEPSY, AUTOSOMAL DOMINANT; ADCADN"]
["SNRPA1","small nuclear ribonucleoprotein polypeptide A' [Source:HGNC Symbol;Acc:11152]","ENSG00000131876","ENSP00000254193",1,"LRR_9[1]","family-655","SNRPA1",".",".","snRNA","snRNA",2928112,"RNAbinding",".",".",1,1,".","GO:0030529,GO:0003723,GO:0005681,GO:0005686,GO:0030532,GO:0071013,GO:0008380,GO:0000398","ribonucleoprotein complex,RNA binding,spliceosomal complex,U2 snRNP,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome","GO:0030529,GO:0019013,GO:0003723,GO:0005515,GO:0005654,GO:0005681,GO:0005686,GO:0030532,GO:0071013,GO:0010467,GO:0008380,GO:0000398","ribonucleoprotein complex,viral nucleocapsid,RNA binding,protein binding,nucleoplasm,spliceosomal complex,U2 snRNP,small nuclear ribonucleoprotein complex,catalytic step 2 spliceosome,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["API5","apoptosis inhibitor 5 [Source:HGNC Symbol;Acc:594]","ENSG00000166181","ENSP00000436189",1,"API5[1]","family-656","API5",".",".","mRNA","putative mRNA","22658674, 22681889","candidate mRNA binder","RNArelated",1,1,1,".","GO:0005681","spliceosomal complex","GO:0005488,GO:0005634,GO:0005515,GO:0017134,GO:0005737,GO:0005681,GO:0006915,GO:0043066,GO:2000270","binding,nucleus,protein binding,fibroblast growth factor binding,cytoplasm,spliceosomal complex,apoptotic process,negative regulation of apoptotic process,negative regulation of fibroblast apoptotic process","."]
["SHQ1","SHQ1, H/ACA ribonucleoprotein assembly factor [Source:HGNC Symbol;Acc:25543]","ENSG00000144736","ENSP00000417452",1,"SHQ1[1]","family-657","SHQ1",".",".","snoRNA","snoRNA",19383767,".",".",".",".",".",".","GO:0022618,GO:2000233","ribonucleoprotein complex assembly,negative regulation of rRNA processing","GO:0005634,GO:0005737,GO:0005515,GO:0005829,GO:0005654,GO:0043065,GO:0022618,GO:2000233","nucleus,cytoplasm,protein binding,cytosol,nucleoplasm,positive regulation of apoptotic process,ribonucleoprotein complex assembly,negative regulation of rRNA processing","."]
["AKAP1","A kinase (PRKA) anchor protein 1 [Source:HGNC Symbol;Acc:367]","ENSG00000121057","ENSP00000459895",3,"TUDOR[1],KH_1[1],DUF3552[1]","family-658","AKAP1",".",".","mRNA","mRNA",23077346,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0016021,GO:0005739,GO:0005829,GO:0005741,GO:0007596","RNA binding,protein binding,integral to membrane,mitochondrion,cytosol,mitochondrial outer membrane,blood coagulation","."]
["FTO","fat mass and obesity associated [Source:HGNC Symbol;Acc:24678]","ENSG00000140718","ENSP00000418823",2,"FTO_CTD[1],FTO_NTD[1]","family-659","FTO",".",".","mRNA","mRNA",23653210,".",".",".",".",".",".","GO:0035515,GO:0035553,GO:0042245","oxidative RNA demethylase activity,oxidative single-stranded RNA demethylation,RNA repair","GO:0035515,GO:0035516,GO:0043734,GO:0005634,GO:0060612,GO:0001659,GO:0010883,GO:0035552,GO:0035553,GO:0040014,GO:0042245,GO:0044065,GO:0070350,GO:0008198,GO:0080111,GO:0070989,GO:0006307","oxidative RNA demethylase activity,oxidative DNA demethylase activity,DNA-N1-methyladenine dioxygenase activity,nucleus,adipose tissue development,temperature homeostasis,regulation of lipid storage,oxidative single-stranded DNA demethylation,oxidative single-stranded RNA demethylation,regulation of multicellular organism growth,RNA repair,regulation of respiratory system process,regulation of white fat cell proliferation,ferrous iron binding,DNA demethylation,oxidative demethylation,DNA dealkylation involved in DNA repair"," GROWTH RETARDATION, DEVELOPMENTAL DELAY, COARSE FACIES, AND EARLY"]
["PUF60","poly-U binding splicing factor 60KDa [Source:HGNC Symbol;Acc:17042]","ENSG00000179950","ENSP00000431960",3,"RRM_5[1],RRM_1[2]","family-66","PUF60",".",".","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0030529,GO:0006397,GO:0008380","RNA binding,ribonucleoprotein complex,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0005634,GO:0003723,GO:0005515,GO:0003677,GO:0042802,GO:0030529,GO:0019907,GO:0006351,GO:0006915,GO:0006355,GO:0006397,GO:0008380","nucleotide binding,nucleic acid binding,nucleus,RNA binding,protein binding,DNA binding,identical protein binding,ribonucleoprotein complex,cyclin-dependent protein kinase activating kinase holoenzyme complex,transcription, DNA-templated,apoptotic process,regulation of transcription, DNA-dependent,mRNA processing,RNA splicing","."]
["SAMHD1","SAM domain and HD domain 1 [Source:HGNC Symbol;Acc:15925]","ENSG00000101347","ENSP00000262878",2,"SAM_2[1],HD[1]","family-660","SAMHD1",".",".","diverse","RNA/DNA","established RBP ",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0046872,GO:0008081,GO:0003723,GO:0005515,GO:0003676,GO:0003824,GO:0005634,GO:0005622,GO:0045087,GO:0006955,GO:0051607,GO:0045088","metal ion binding,phosphoric diester hydrolase activity,RNA binding,protein binding,nucleic acid binding,catalytic activity,nucleus,intracellular,innate immune response,immune response,defense response to virus,regulation of innate immune response"," AICARDI-GOUTIERES SYNDROME 5; AGS5"]
["RBM45","RNA binding motif protein 45 [Source:HGNC Symbol;Acc:24468]","ENSG00000155636","ENSP00000286070",4,"RRM_5[1],RRM_1[3]","family-661","RBM45",".",".","mRNA","putative mRNA",12220514,"RNAbinding","experimentally validated",1,1,1,1,"GO:0003723","RNA binding","GO:0003676,GO:0000166,GO:0003723,GO:0005634,GO:0005737,GO:0030154,GO:0007399","nucleic acid binding,nucleotide binding,RNA binding,nucleus,cytoplasm,cell differentiation,nervous system development","."]
["FAM98B","family with sequence similarity 98, member B [Source:HGNC Symbol;Acc:26773]","ENSG00000171262","ENSP00000380734",1,"DUF2465[1]","family-662","FAM98A,FAM98B,FAM98C","FAM98A","FAM98B[45,54],FAM98C[25,37]","tRNA","putative tRNA",21311021,"candidate mRNA binder",".",".",1,1,".","GO:0072669","tRNA-splicing ligase complex","GO:0072669","tRNA-splicing ligase complex","."]
["FAM98A","family with sequence similarity 98, member A [Source:HGNC Symbol;Acc:24520]","ENSG00000119812","ENSP00000398490",1,"DUF2465[1]","family-662","FAM98A,FAM98B,FAM98C","FAM98A","FAM98B[45,54],FAM98C[25,37]","mRNA","mRNA","established RBP ","candidate mRNA binder","novel",1,1,".",".",".",".",".",".","."]
["FAM98C","family with sequence similarity 98, member C [Source:HGNC Symbol;Acc:27119]","ENSG00000130244","ENSP00000340348",2,"DUF2465[2]","family-662","FAM98A,FAM98B,FAM98C","FAM98A","FAM98B[45,54],FAM98C[25,37]","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".",".",".","."]
["PCF11","PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:30097]","ENSG00000165494","ENSP00000298281",1,"CTD_bind[1]","family-663","PCF11",".",".","mRNA","mRNA",19110458,".",".",".",".",".",".","GO:0005849,GO:0008380,GO:0000398,GO:0006379,GO:0031124","mRNA cleavage factor complex,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing","GO:0005654,GO:0005849,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006379,GO:0031124,GO:0006369","nucleoplasm,mRNA cleavage factor complex,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["EIF5","eukaryotic translation initiation factor 5 [Source:HGNC Symbol;Acc:3299]","ENSG00000100664","ENSP00000376477",2,"eIF-5_eIF-2B[1],W2[1]","family-664","EIF5",".",".","mRNA","mRNA",24499181,"translationfactor",".",".",1,".",".","GO:0003743,GO:0008135,GO:0006412,GO:0006446,GO:0006413","translation initiation factor activity,translation factor activity, nucleic acid binding,translation,regulation of translational initiation,translational initiation","GO:0005488,GO:0005515,GO:0005525,GO:0003924,GO:0003743,GO:0008135,GO:0005737,GO:0005829,GO:0006412,GO:0010467,GO:0006446,GO:0044267,GO:0006184,GO:0006413","binding,protein binding,GTP binding,GTPase activity,translation initiation factor activity,translation factor activity, nucleic acid binding,cytoplasm,cytosol,translation,gene expression,regulation of translational initiation,cellular protein metabolic process,GTP catabolic process,translational initiation","."]
["ZC3HC1","zinc finger, C3HC-type containing 1 [Source:HGNC Symbol;Acc:29913]","ENSG00000091732","ENSP00000309301",3,"zf-C3HC[1],Rsm1[2]","family-665","ZC3HC1",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".","GO:0005515,GO:0008270,GO:0019901,GO:0005634,GO:0031965,GO:0016567,GO:0043066,GO:0007067,GO:2001240","protein binding,zinc ion binding,protein kinase binding,nucleus,nuclear membrane,protein ubiquitination,negative regulation of apoptotic process,mitosis,negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","."]
["HNRNPC","heterogeneous nuclear ribonucleoprotein C (C1/C2) [Source:HGNC Symbol;Acc:5035]","ENSG00000092199","ENSP00000450669",1,"RRM_1[1]","family-666","HNRNPC,HNRNPCL1,RALY,RALYL","HNRNPC","HNRNPCL1[87,91],RALY[44,44],RALYL[49,49]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0005681,GO:0071013,GO:0008380,GO:0000398,GO:0030529","RNA binding,mRNA binding,spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003729,GO:0042802,GO:0005654,GO:0005681,GO:0045120,GO:0071013,GO:0010467,GO:0038032,GO:0008380,GO:0000398,GO:0030529,GO:0019013","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA binding,identical protein binding,nucleoplasm,spliceosomal complex,pronucleus,catalytic step 2 spliceosome,gene expression,termination of G-protein coupled receptor signaling pathway,RNA splicing,mRNA splicing, via spliceosome,ribonucleoprotein complex,viral nucleocapsid","."]
["HNRNPCL1","heterogeneous nuclear ribonucleoprotein C-like 1 [Source:HGNC Symbol;Acc:29295]","ENSG00000179172","ENSP00000365370",1,"RRM_1[1]","family-666","HNRNPC,HNRNPCL1,RALY,RALYL","HNRNPC","HNRNPCL1[87,91],RALY[44,44],RALYL[49,49]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0030529","nucleotide binding,RNA binding,nucleic acid binding,nucleus,ribonucleoprotein complex","."]
["RALY","RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) [Source:HGNC Symbol;Acc:15921]","ENSG00000125970","ENSP00000415973",1,"RRM_1[1]","family-666","HNRNPC,HNRNPCL1,RALY,RALYL","HNRNPC","HNRNPCL1[87,91],RALY[44,44],RALYL[49,49]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0071013,GO:0000398","RNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0071013,GO:0000398","nucleotide binding,nucleic acid binding,RNA binding,nucleus,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["RALYL","RALY RNA binding protein-like [Source:HGNC Symbol;Acc:27036]","ENSG00000184672","ENSP00000430128",1,"RRM_1[1]","family-666","HNRNPC,HNRNPCL1,RALY,RALYL","HNRNPC","HNRNPCL1[87,91],RALY[44,44],RALYL[49,49]","mRNA","mRNA","established RBP ",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["SEPSECS","Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase [Source:HGNC Symbol;Acc:30605]","ENSG00000109618","ENSP00000371535",1,"SLA_LP_auto_ag[1]","family-667","SEPSECS",".",".","tRNA","tRNA","The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).[provided by RefSeq, Mar 2011]",".",".",".",".",".",".","GO:0000049","tRNA binding","GO:0005515,GO:0016740,GO:0030170,GO:0000049,GO:0016785,GO:0005634,GO:0005737,GO:0097056,GO:0001514","protein binding,transferase activity,pyridoxal phosphate binding,tRNA binding,transferase activity, transferring selenium-containing groups,nucleus,cytoplasm,selenocysteinyl-tRNA(Sec) biosynthetic process,selenocysteine incorporation"," PONTOCEREBELLAR HYPOPLASIA, TYPE 2D; PCH2D"]
["NPM1","nucleophosmin (nucleolar phosphoprotein B23, numatrin) [Source:HGNC Symbol;Acc:7910]","ENSG00000181163","ENSP00000341168",1,"Nucleoplasmin[1]","family-668","NPM1,NPM3,NPM2","NPM1","NPM3[20,33],NPM2[21,29]","rRNA","rRNA",12058066,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0043024,GO:0043023,GO:0030529,GO:0045727,GO:0042255,GO:0060699,GO:0060735","RNA binding,ribosomal small subunit binding,ribosomal large subunit binding,ribonucleoprotein complex,positive regulation of translation,ribosome assembly,regulation of endoribonuclease activity,regulation of eIF2 alpha phosphorylation by dsRNA","GO:0003676,GO:0003723,GO:0005515,GO:0042803,GO:0046982,GO:0051082,GO:0019901,GO:0003713,GO:0042393,GO:0051059,GO:0043024,GO:0004860,GO:0030957,GO:0043023,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0005654,GO:0005813,GO:0030529,GO:0031616,GO:0008285,GO:0043066,GO:0007165,GO:0006281,GO:0016032,GO:0006334,GO:0006950,GO:0006886,GO:0008104,GO:0045727,GO:0034080,GO:0051092,GO:0042255,GO:0006913,GO:0007569,GO:0007098,GO:0051259,GO:0019048,GO:0010826,GO:0032071,GO:0044387,GO:0046599,GO:0060699,GO:0060735","nucleic acid binding,RNA binding,protein binding,protein homodimerization activity,protein heterodimerization activity,unfolded protein binding,protein kinase binding,transcription coactivator activity,histone binding,NF-kappaB binding,ribosomal small subunit binding,protein kinase inhibitor activity,Tat protein binding,ribosomal large subunit binding,nucleus,cytoplasm,cytosol,nucleolus,nucleoplasm,centrosome,ribonucleoprotein complex,spindle pole centrosome,negative regulation of cell proliferation,negative regulation of apoptotic process,signal transduction,DNA repair,viral process,nucleosome assembly,response to stress,intracellular protein transport,protein localization,positive regulation of translation,CENP-A containing nucleosome assembly at centromere,positive regulation of NF-kappaB transcription factor activity,ribosome assembly,nucleocytoplasmic transport,cell aging,centrosome cycle,protein oligomerization,modulation by virus of host morphology or physiology,negative regulation of centrosome duplication,regulation of endodeoxyribonuclease activity,negative regulation of protein kinase activity by regulation of protein phosphorylation,regulation of centriole replication,regulation of endoribonuclease activity,regulation of eIF2 alpha phosphorylation by dsRNA","."]
["NPM3","nucleophosmin/nucleoplasmin 3 [Source:HGNC Symbol;Acc:7931]","ENSG00000107833","ENSP00000359128",1,"Nucleoplasmin[1]","family-668","NPM1,NPM3,NPM2","NPM1","NPM3[20,33],NPM2[21,29]","rRNA","putative rRNA",15596447,"candidate mRNA binder","RNArelated",1,1,1,".","GO:0006364,GO:0009303","rRNA processing,rRNA transcription","GO:0005515,GO:0003676,GO:0005730,GO:0006364,GO:0009303","protein binding,nucleic acid binding,nucleolus,rRNA processing,rRNA transcription","."]
["NPM2","nucleophosmin/nucleoplasmin 2 [Source:HGNC Symbol;Acc:7930]","ENSG00000158806","ENSP00000289820",1,"Nucleoplasmin[1]","family-668","NPM1,NPM3,NPM2","NPM1","NPM3[20,33],NPM2[21,29]","rRNA","putative rRNA","by homology",".",".",".",".",".",".",".",".","GO:0003676,GO:0019899,GO:0051260,GO:0045740,GO:0043085,GO:0042393,GO:0005634,GO:0005730,GO:0000790,GO:0000789,GO:0009790,GO:0007338,GO:0045836,GO:0006338,GO:0007096,GO:0009994,GO:0051054","nucleic acid binding,enzyme binding,protein homooligomerization,positive regulation of DNA replication,positive regulation of catalytic activity,histone binding,nucleus,nucleolus,nuclear chromatin,cytoplasmic chromatin,embryo development,single fertilization,positive regulation of meiosis,chromatin remodeling,regulation of exit from mitosis,oocyte differentiation,positive regulation of DNA metabolic process","."]
["NUPL2","nucleoporin like 2 [Source:HGNC Symbol;Acc:17010]","ENSG00000136243","ENSP00000387330",1,"zf-CCCH[1]","family-669","NUPL2",".",".","mRNA","putative mRNA","by homology, 16000379","RNAbinding",".",".",1,".",1,"GO:0051028","mRNA transport","GO:0046872,GO:0005049,GO:0005634,GO:0005829,GO:0031965,GO:0005643,GO:0055085,GO:0044281,GO:0006611,GO:0000278,GO:0016032,GO:0005975,GO:0051028,GO:0019221,GO:0010827,GO:0015758,GO:0007077,GO:0008645","metal ion binding,nuclear export signal receptor activity,nucleus,cytosol,nuclear membrane,nuclear pore,transmembrane transport,small molecule metabolic process,protein export from nucleus,mitotic cell cycle,viral process,carbohydrate metabolic process,mRNA transport,cytokine-mediated signaling pathway,regulation of glucose transport,glucose transport,mitotic nuclear envelope disassembly,hexose transport","."]
["MRPS14","mitochondrial ribosomal protein S14 [Source:HGNC Symbol;Acc:14049]","ENSG00000120333","ENSP00000420714",1,"Ribosomal_S14[1]","family-67","MRPS14",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0005761,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial ribosome,translation","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0031965,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrion,intracellular,ribosome,nuclear membrane,mitochondrial ribosome,translation","."]
["SF3A1","splicing factor 3a, subunit 1, 120kDa [Source:HGNC Symbol;Acc:10765]","ENSG00000099995","ENSP00000390336",4,"ubiquitin[1],PRP21_like_P[1],Surp[2]","family-670","SF3A1",".",".","snRNA","snRNA","This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP (also called SWAP or Suppressor-of-White-APricot) motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through sequences carboxy-terminal to the SURP motifs. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006396,GO:0005681,GO:0071013,GO:0005684,GO:0006397,GO:0008380,GO:0000398,GO:0000389","RNA binding,RNA processing,spliceosomal complex,catalytic step 2 spliceosome,U2-type spliceosomal complex,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-splice site recognition","GO:0003723,GO:0005515,GO:0005634,GO:0006396,GO:0005654,GO:0005681,GO:0071013,GO:0005684,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0000389","RNA binding,protein binding,nucleus,RNA processing,nucleoplasm,spliceosomal complex,catalytic step 2 spliceosome,U2-type spliceosomal complex,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-splice site recognition","."]
["EIF3A","eukaryotic translation initiation factor 3, subunit A [Source:HGNC Symbol;Acc:3271]","ENSG00000107581","ENSP00000358140",1,"PCI[1]","family-671","EIF3A",".",".","mRNA","mRNA",23766293,"translationfactor","novel",1,1,1,".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0001732,GO:0006412,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,formation of translation initiation complex,translation,translational initiation","GO:0005515,GO:0003743,GO:0005634,GO:0005737,GO:0005730,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0001732,GO:0005198,GO:0005829,GO:0006412,GO:0010467,GO:0044267,GO:0006413","protein binding,translation initiation factor activity,nucleus,cytoplasm,nucleolus,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,formation of translation initiation complex,structural molecule activity,cytosol,translation,gene expression,cellular protein metabolic process,translational initiation","."]
["FASTKD5","FAST kinase domains 5 [Source:HGNC Symbol;Acc:25790]","ENSG00000215251","ENSP00000369618",3,"FAST_1[1],FAST_2[1],RAP[1]","family-672","FASTKD5",".",".","mRNA","putative mRNA",15501674,"candidate mRNA binder",".",".",1,".",".",".",".","GO:0004672,GO:0005739,GO:0045333","protein kinase activity,mitochondrion,cellular respiration","."]
["TDRD3","tudor domain containing 3 [Source:HGNC Symbol;Acc:20612]","ENSG00000083544","ENSP00000440190",3,"TUDOR[1],DUF1767[1],UBA[1]","family-673","TDRD3",".",".","mRNA","mRNA related",18664458,"candidate mRNA binder","RNAbinding",1,1,".",".","GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0003723,GO:0005515,GO:0035064,GO:0003682,GO:0003713,GO:0005634,GO:0005737,GO:0035145,GO:0006397,GO:0016568","RNA binding,protein binding,methylated histone residue binding,chromatin binding,transcription coactivator activity,nucleus,cytoplasm,exon-exon junction complex,mRNA processing,chromatin modification","."]
["SNRPB","small nuclear ribonucleoprotein polypeptides B and B1 [Source:HGNC Symbol;Acc:11153]","ENSG00000125835","ENSP00000370746",1,"LSM[1]","family-674","SNRPB,SNRPN","SNRPB","SNRPN[93,93]","snRNA","snRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0071208,GO:0005681,GO:0071204,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0016070,GO:0008380,GO:0000398,GO:0031124,GO:0000387,GO:0034660,GO:0008334","histone pre-mRNA DCP binding,spliceosomal complex,histone pre-mRNA 3'end processing complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,histone mRNA metabolic process","GO:0005515,GO:0071208,GO:0005737,GO:0005634,GO:0005829,GO:0005654,GO:0005681,GO:0071204,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0006366,GO:0010467,GO:0016070,GO:0008380,GO:0000398,GO:0031124,GO:0000387,GO:0034660,GO:0006369,GO:0008334","protein binding,histone pre-mRNA DCP binding,cytoplasm,nucleus,cytosol,nucleoplasm,spliceosomal complex,histone pre-mRNA 3'end processing complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["SNRPN","small nuclear ribonucleoprotein polypeptide N [Source:HGNC Symbol;Acc:11164]","ENSG00000128739","ENSP00000408767",1,"LSM[1]","family-674","SNRPB,SNRPN","SNRPB","SNRPN[93,93]","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0030529,GO:0005681,GO:0005685,GO:0005686,GO:0030532,GO:0008380","RNA binding,ribonucleoprotein complex,spliceosomal complex,U1 snRNP,U2 snRNP,small nuclear ribonucleoprotein complex,RNA splicing","GO:0003723,GO:0005634,GO:0030529,GO:0019013,GO:0005515,GO:0005681,GO:0005685,GO:0005686,GO:0030532,GO:0008380,GO:0009725","RNA binding,nucleus,ribonucleoprotein complex,viral nucleocapsid,protein binding,spliceosomal complex,U1 snRNP,U2 snRNP,small nuclear ribonucleoprotein complex,RNA splicing,response to hormone","."]
["YRDC","yrdC domain containing (E. coli) [Source:HGNC Symbol;Acc:28905]","ENSG00000196449","ENSP00000362135",1,"Sua5_yciO_yrdC[1]","family-675","YRDC",".",".","tRNA","putative tRNA",23258706,".",".",".",".",".",".","GO:0003725","double-stranded RNA binding","GO:0005515,GO:0003725,GO:0005739,GO:0016020,GO:0051051","protein binding,double-stranded RNA binding,mitochondrion,membrane,negative regulation of transport","."]
["POLR2K","polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa [Source:HGNC Symbol;Acc:9198]","ENSG00000147669","ENSP00000342889",1,"DNA_RNApol_7kD[1]","family-676","POLR2K",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003899,GO:0006351,GO:0008270,GO:0001055,GO:0001056,GO:0001054,GO:0005634,GO:0005829,GO:0005654,GO:0005665,GO:0005736,GO:0005666,GO:0006366,GO:0045087,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0006383,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006360,GO:0006370,GO:0006361,GO:0032481,GO:0006283,GO:0050434,GO:0006385,GO:0006386,GO:0006362,GO:0006363,GO:0006356","DNA binding,DNA-directed RNA polymerase activity,transcription, DNA-templated,zinc ion binding,RNA polymerase II activity,RNA polymerase III activity,RNA polymerase I activity,nucleus,cytosol,nucleoplasm,DNA-directed RNA polymerase II, core complex,DNA-directed RNA polymerase I complex,DNA-directed RNA polymerase III complex,transcription from RNA polymerase II promoter,innate immune response,nucleotide-excision repair,DNA repair,viral process,gene expression,transcription from RNA polymerase III promoter,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,transcription from RNA polymerase I promoter,7-methylguanosine mRNA capping,transcription initiation from RNA polymerase I promoter,positive regulation of type I interferon production,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription,transcription elongation from RNA polymerase III promoter,termination of RNA polymerase III transcription,transcription elongation from RNA polymerase I promoter,termination of RNA polymerase I transcription,regulation of transcription from RNA polymerase I promoter","."]
["ERN2","endoplasmic reticulum to nucleus signaling 2 [Source:HGNC Symbol;Acc:16942]","ENSG00000134398","ENSP00000256797",3,"PQQ_2[1],Pkinase[1],Ribonuc_2-5A[1]","family-677","ERN1,ERN2","ERN1","ERN2[49,49]","mRNA","mRNA","18242182,  21146530",".",".",".",".",".",".","GO:0004540,GO:0006397,GO:0016075","ribonuclease activity,mRNA processing,rRNA catabolic process","GO:0005515,GO:0004540,GO:0016772,GO:0006397,GO:0005524,GO:0004674,GO:0004519,GO:0000287,GO:0004672,GO:0004713,GO:0016021,GO:0005789,GO:0006355,GO:0034976,GO:0070059,GO:0006351,GO:0045892,GO:0006950,GO:0006468,GO:0007050,GO:0016075,GO:0030263","protein binding,ribonuclease activity,transferase activity, transferring phosphorus-containing groups,mRNA processing,ATP binding,protein serine/threonine kinase activity,endonuclease activity,magnesium ion binding,protein kinase activity,protein tyrosine kinase activity,integral to membrane,endoplasmic reticulum membrane,regulation of transcription, DNA-dependent,response to endoplasmic reticulum stress,intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,transcription, DNA-templated,negative regulation of transcription, DNA-dependent,response to stress,protein phosphorylation,cell cycle arrest,rRNA catabolic process,apoptotic chromosome condensation","."]
["ERN1","endoplasmic reticulum to nucleus signaling 1 [Source:HGNC Symbol;Acc:3449]","ENSG00000178607","ENSP00000401445",3,"PQQ_2[1],Pkinase[1],Ribonuc_2-5A[1]","family-677","ERN1,ERN2","ERN1","ERN2[49,49]","mRNA","mRNA/miRNA","IRE1 RNA endonuclease",".",".",".",".",".",".","GO:0004521,GO:0004540,GO:0006397","endoribonuclease activity,ribonuclease activity,mRNA processing","GO:0005515,GO:0005524,GO:0004674,GO:0000287,GO:0042802,GO:0004521,GO:0005739,GO:0005789,GO:0030176,GO:0005637,GO:0006351,GO:0006915,GO:0006355,GO:0006468,GO:0007050,GO:0046777,GO:0044267,GO:0030968,GO:0006987,GO:0070055,GO:1900103,GO:0004519,GO:0004672,GO:0004713,GO:0004540,GO:0016772,GO:0070059,GO:0006397","protein binding,ATP binding,protein serine/threonine kinase activity,magnesium ion binding,identical protein binding,endoribonuclease activity,mitochondrion,endoplasmic reticulum membrane,integral to endoplasmic reticulum membrane,nuclear inner membrane,transcription, DNA-templated,apoptotic process,regulation of transcription, DNA-dependent,protein phosphorylation,cell cycle arrest,protein autophosphorylation,cellular protein metabolic process,endoplasmic reticulum unfolded protein response,activation of signaling protein activity involved in unfolded protein response,HAC1-type intron splice site recognition and cleavage,positive regulation of endoplasmic reticulum unfolded protein response,endonuclease activity,protein kinase activity,protein tyrosine kinase activity,ribonuclease activity,transferase activity, transferring phosphorus-containing groups,intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress,mRNA processing","."]
["RPL5","ribosomal protein L5 [Source:HGNC Symbol;Acc:10360]","ENSG00000122406","ENSP00000359345",2,"Ribosomal_L18p[1],Ribosomal_L18_c[1]","family-678","RPL5",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0008097,GO:0005840,GO:0006412,GO:0003723,GO:0030529,GO:0022625,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,5S rRNA binding,ribosome,translation,RNA binding,ribonucleoprotein complex,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0008097,GO:0005622,GO:0005840,GO:0006412,GO:0005515,GO:0003723,GO:0005634,GO:0005829,GO:0005730,GO:0030529,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,5S rRNA binding,intracellular,ribosome,translation,protein binding,RNA binding,nucleus,cytosol,nucleolus,ribonucleoprotein complex,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription"," DIAMOND-BLACKFAN ANEMIA 6; DBA6"]
["RPS17","ribosomal protein S17 [Source:HGNC Symbol;Acc:10397]","ENSG00000184779","ENSP00000453564",1,"Ribosomal_S17e[1]","family-679","RPS17,RPS17L","RPS17","RPS17L[100,100]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0000028,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,ribosomal small subunit assembly,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005829,GO:0022627,GO:0000028,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0034101,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","structural constituent of ribosome,intracellular,ribosome,translation,cytosol,cytosolic small ribosomal subunit,ribosomal small subunit assembly,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,erythrocyte homeostasis,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis"," DIAMOND-BLACKFAN ANEMIA 4; DBA4"]
["RPS17L","ribosomal protein S17-like [Source:HGNC Symbol;Acc:40029]","ENSG00000182774","ENSP00000453910",1,"Ribosomal_S17e[1]","family-679","RPS17,RPS17L","RPS17","RPS17L[100,100]","ribosome","ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0000028,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,ribosomal small subunit assembly,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005829,GO:0022627,GO:0000028,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0034101,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","structural constituent of ribosome,intracellular,ribosome,translation,cytosol,cytosolic small ribosomal subunit,ribosomal small subunit assembly,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,erythrocyte homeostasis,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis"," DIAMOND-BLACKFAN ANEMIA 4; DBA4"]
["DARS","aspartyl-tRNA synthetase [Source:HGNC Symbol;Acc:2678]","ENSG00000115866","ENSP00000264161",2,"tRNA-synt_2[1],tRNA_anti-codon[1]","family-68","DARS",".",".","tRNA","tRNA","established RBP ",".","RNArelated",".",1,".",".","GO:0004812,GO:0004815,GO:0006418,GO:0006422,GO:0006412","aminoacyl-tRNA ligase activity,aspartate-tRNA ligase activity,tRNA aminoacylation for protein translation,aspartyl-tRNA aminoacylation,translation","GO:0000166,GO:0005524,GO:0004812,GO:0004815,GO:0005737,GO:0006418,GO:0006422,GO:0003676,GO:0005515,GO:0004046,GO:0005829,GO:0006412,GO:0010467,GO:0006461","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,aspartate-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,aspartyl-tRNA aminoacylation,nucleic acid binding,protein binding,aminoacylase activity,cytosol,translation,gene expression,protein complex assembly"," HYPOMYELINATION WITH BRAINSTEM AND SPINAL CORD INVOLVEMENT AND LEG"]
["IPO7","importin 7 [Source:HGNC Symbol;Acc:9852]","ENSG00000205339","ENSP00000369042",2,"Cse1[1],IBN_N[1]","family-680","IPO7,IPO8","IPO7","IPO8[64,64]","mRNA","putative mRBP transport",9214382,".",".",".",".",".",".",".",".","GO:0008536,GO:0042393,GO:0005488,GO:0006886,GO:0006606,GO:0005515,GO:0005215,GO:0005083,GO:0005737,GO:0005794,GO:0005643,GO:0007165,GO:0019048","Ran GTPase binding,histone binding,binding,intracellular protein transport,protein import into nucleus,protein binding,transporter activity,small GTPase regulator activity,cytoplasm,Golgi apparatus,nuclear pore,signal transduction,modulation by virus of host morphology or physiology","."]
["IPO8","importin 8 [Source:HGNC Symbol;Acc:9853]","ENSG00000133704","ENSP00000256079",2,"Cse1[1],IBN_N[1]","family-680","IPO7,IPO8","IPO7","IPO8[64,64]","ncRNA","putative miRBP transport",24596094,".",".",".",".",".",".",".",".","GO:0008536,GO:0005488,GO:0006886,GO:0005515,GO:0005634,GO:0005737,GO:0007165","Ran GTPase binding,binding,intracellular protein transport,protein binding,nucleus,cytoplasm,signal transduction","."]
["SMN1","survival of motor neuron 1, telomeric [Source:HGNC Symbol;Acc:11117]","ENSG00000172062","ENSP00000305857",1,"SMN[1]","family-681","SMN1,SMN2","SMN1","SMN2[100,100]","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0005681,GO:0016070,GO:0006397,GO:0000245,GO:0000387,GO:0034660","RNA binding,spliceosomal complex,RNA metabolic process,mRNA processing,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0003723,GO:0005515,GO:0042802,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005681,GO:0030018,GO:0097504,GO:0010467,GO:0016070,GO:0006397,GO:0007399,GO:0008219,GO:0000245,GO:0000387,GO:0034660","RNA binding,protein binding,identical protein binding,nucleus,cytoplasm,cytosol,nucleoplasm,spliceosomal complex,Z disc,Gemini of coiled bodies,gene expression,RNA metabolic process,mRNA processing,nervous system development,cell death,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process"," SPINAL MUSCULAR ATROPHY, TYPE I; SMA1"]
["SMN2","survival of motor neuron 2, centromeric [Source:HGNC Symbol;Acc:11118]","ENSG00000205571","ENSP00000370117",1,"SMN[1]","family-681","SMN1,SMN2","SMN1","SMN2[100,100]","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0006397,GO:0005681,GO:0016070,GO:0000245,GO:0000387,GO:0034660","RNA binding,mRNA processing,spliceosomal complex,RNA metabolic process,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0003723,GO:0005634,GO:0005737,GO:0006397,GO:0005515,GO:0042802,GO:0005829,GO:0005654,GO:0005681,GO:0030018,GO:0097504,GO:0010467,GO:0016070,GO:0007399,GO:0008219,GO:0000245,GO:0000387,GO:0034660","RNA binding,nucleus,cytoplasm,mRNA processing,protein binding,identical protein binding,cytosol,nucleoplasm,spliceosomal complex,Z disc,Gemini of coiled bodies,gene expression,RNA metabolic process,nervous system development,cell death,spliceosomal complex assembly,spliceosomal snRNP assembly,ncRNA metabolic process"," SPINAL MUSCULAR ATROPHY, TYPE I; SMA1"]
["GTPBP4","GTP binding protein 4 [Source:HGNC Symbol;Acc:21535]","ENSG00000107937","ENSP00000354040",2,"NOG1[1],NOGCT[1]","family-682","GTPBP4",".",".","rRNA","putative rRNA","NOG1 yeast homolog","candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005525,GO:0015093,GO:0016021,GO:0005634,GO:0005737,GO:0005622,GO:0005730,GO:0005794,GO:0031965,GO:0007264,GO:0015684,GO:0042254,GO:0005515,GO:0003924,GO:0048471,GO:0008285,GO:0030336,GO:0000079,GO:0008156,GO:0050821,GO:0031397,GO:0022408,GO:0006184,GO:0033342","GTP binding,ferrous iron transmembrane transporter activity,integral to membrane,nucleus,cytoplasm,intracellular,nucleolus,Golgi apparatus,nuclear membrane,small GTPase mediated signal transduction,ferrous iron transport,ribosome biogenesis,protein binding,GTPase activity,perinuclear region of cytoplasm,negative regulation of cell proliferation,negative regulation of cell migration,regulation of cyclin-dependent protein serine/threonine kinase activity,negative regulation of DNA replication,protein stabilization,negative regulation of protein ubiquitination,negative regulation of cell-cell adhesion,GTP catabolic process,negative regulation of collagen binding","."]
["MRPL13","mitochondrial ribosomal protein L13 [Source:HGNC Symbol;Acc:14278]","ENSG00000172172","ENSP00000430545",1,"Ribosomal_L13[1]","family-683","MRPL13",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0005761,GO:0005762","structural constituent of ribosome,ribosome,translation,mitochondrial ribosome,mitochondrial large ribosomal subunit","GO:0003735,GO:0005739,GO:0005840,GO:0006412,GO:0005515,GO:0005761,GO:0005762","structural constituent of ribosome,mitochondrion,ribosome,translation,protein binding,mitochondrial ribosome,mitochondrial large ribosomal subunit","."]
["MRPL46","mitochondrial ribosomal protein L46 [Source:HGNC Symbol;Acc:1192]","ENSG00000259494","ENSP00000312311",1,"MRP-L46[1]","family-684","MRPL46",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840","ribosome","GO:0016787,GO:0005739,GO:0005840","hydrolase activity,mitochondrion,ribosome","."]
["LSM5","LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:17162]","ENSG00000106355","ENSP00000386707",1,"LSM[1]","family-685","LSM5",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0043928","RNA binding,spliceosomal complex,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0005634,GO:0005829,GO:0005681,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0043928","RNA binding,protein binding,nucleus,cytosol,spliceosomal complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["EIF4G3","eukaryotic translation initiation factor 4 gamma, 3 [Source:HGNC Symbol;Acc:3298]","ENSG00000075151","ENSP00000264211",3,"MIF4G[1],MA3[1],W2[1]","family-686","EIF4G1,EIF4G3,EIF4G2","EIF4G1","EIF4G3[48,49],EIF4G2[16,28]","mRNA","mRNA",10872469,"translationfactor","RNAbinding",1,1,".",".","GO:0003743,GO:0003723,GO:0045727,GO:0000339,GO:0008135,GO:0016281,GO:0006446","translation initiation factor activity,RNA binding,positive regulation of translation,RNA cap binding,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 4F complex,regulation of translational initiation","GO:0003743,GO:0005488,GO:0003723,GO:0005515,GO:0007283,GO:0001934,GO:0045727,GO:0060903,GO:0000339,GO:0008135,GO:0005829,GO:0016281,GO:0019221,GO:0006446,GO:0019048","translation initiation factor activity,binding,RNA binding,protein binding,spermatogenesis,positive regulation of protein phosphorylation,positive regulation of translation,positive regulation of meiosis I,RNA cap binding,translation factor activity, nucleic acid binding,cytosol,eukaryotic translation initiation factor 4F complex,cytokine-mediated signaling pathway,regulation of translational initiation,modulation by virus of host morphology or physiology","."]
["EIF4G1","eukaryotic translation initiation factor 4 gamma, 1 [Source:HGNC Symbol;Acc:3296]","ENSG00000114867","ENSP00000343450",3,"MIF4G[1],MA3[1],W2[1]","family-686","EIF4G1,EIF4G3,EIF4G2","EIF4G1","EIF4G3[48,49],EIF4G2[16,28]","mRNA","mRNA","The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]","translationfactor","RNArelated",1,1,1,".","GO:0003723,GO:0003743,GO:0008135,GO:0016281,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006446,GO:0006413,GO:0000184","RNA binding,translation initiation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 4F complex,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translational initiation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005488,GO:0003723,GO:0005515,GO:0003743,GO:0008135,GO:0005737,GO:0005829,GO:0016281,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0008286,GO:0019221,GO:0006446,GO:0008219,GO:0044267,GO:0019048,GO:0006413,GO:0000184","binding,RNA binding,protein binding,translation initiation factor activity,translation factor activity, nucleic acid binding,cytoplasm,cytosol,eukaryotic translation initiation factor 4F complex,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,insulin receptor signaling pathway,cytokine-mediated signaling pathway,regulation of translational initiation,cell death,cellular protein metabolic process,modulation by virus of host morphology or physiology,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"," PARKINSON DISEASE 18; PARK18"]
["EIF4G2","eukaryotic translation initiation factor 4 gamma, 2 [Source:HGNC Symbol;Acc:3297]","ENSG00000110321","ENSP00000433664",3,"MIF4G[1],MA3[1],W2[1]","family-686","EIF4G1,EIF4G3,EIF4G2","EIF4G1","EIF4G3[48,49],EIF4G2[16,28]","mRNA","mRNA","Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]","translationfactor","RNArelated",1,1,1,".","GO:0003723,GO:0003743,GO:0008135,GO:0016281,GO:0006446","RNA binding,translation initiation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 4F complex,regulation of translational initiation","GO:0005488,GO:0003723,GO:0005515,GO:0005737,GO:0003743,GO:0008135,GO:0005829,GO:0016281,GO:0007050,GO:0019221,GO:0006446,GO:0008219","binding,RNA binding,protein binding,cytoplasm,translation initiation factor activity,translation factor activity, nucleic acid binding,cytosol,eukaryotic translation initiation factor 4F complex,cell cycle arrest,cytokine-mediated signaling pathway,regulation of translational initiation,cell death","."]
["GTF2F1","general transcription factor IIF, polypeptide 1, 74kDa [Source:HGNC Symbol;Acc:4652] [Type: protein coding Ensembl/Havana merge]","ENSG00000125651","ENSP00000377969",1,"TFIIF_alpha[1]","family-687","GTF2F1",".",".","mRNA","putative mRNA",12354769,"RNAbinding","RNArelated",1,1,1,".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003824,GO:0005634,GO:0045893,GO:0006367,GO:0045944,GO:0005515,GO:0008134,GO:0019211,GO:0003713,GO:0030054,GO:0005654,GO:0005674,GO:0006366,GO:0009615,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006368,GO:0006370,GO:0050434","DNA binding,catalytic activity,nucleus,positive regulation of transcription, DNA-dependent,transcription initiation from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,protein binding,transcription factor binding,phosphatase activator activity,transcription coactivator activity,cell junction,nucleoplasm,transcription factor TFIIF complex,transcription from RNA polymerase II promoter,response to virus,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,positive regulation of viral transcription","."]
["RPS15A","ribosomal protein S15a [Source:HGNC Symbol;Acc:10389]","ENSG00000134419","ENSP00000318646",1,"Ribosomal_S8[1]","family-688","RPS15A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005737,GO:0005829,GO:0022627,GO:0009615,GO:0008284,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0045787,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,cytoplasm,cytosol,cytosolic small ribosomal subunit,response to virus,positive regulation of cell proliferation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,positive regulation of cell cycle,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["PIH1D2","PIH1 domain containing 2 [Source:HGNC Symbol;Acc:25210]","ENSG00000262740","ENSP00000460262",1,"PIH1[1]","family-689","PIH1D2",".",".","unknown","unknown","established RBP ",".",".",".",".",".",".",".",".",".",".","."]
["TTF2","transcription termination factor, RNA polymerase II [Source:HGNC Symbol;Acc:12398]","ENSG00000116830","ENSP00000358478",3,"zf-GRF[1],Helicase_C[1],SNF2_N[1]","family-69","TTF2",".",".","mRNA","mRNA",12927788,".",".",".",".",".",".","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0005524,GO:0003676,GO:0004386,GO:0005515,GO:0008270,GO:0003677,GO:0008026,GO:0016787,GO:0008094,GO:0005634,GO:0005737,GO:0005681,GO:0008023,GO:0006355,GO:0006397,GO:0008380,GO:0006369,GO:0006353","ATP binding,nucleic acid binding,helicase activity,protein binding,zinc ion binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,DNA-dependent ATPase activity,nucleus,cytoplasm,spliceosomal complex,transcription elongation factor complex,regulation of transcription, DNA-dependent,mRNA processing,RNA splicing,termination of RNA polymerase II transcription,DNA-dependent transcription, termination","."]
["PUS3","pseudouridylate synthase 3 [Source:HGNC Symbol;Acc:25461]","ENSG00000110060","ENSP00000432386",2,"PseudoU_synth_1[2]","family-690","PUS3",".",".","tRNA","tRNA","The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]",".",".",".",".",".",".","GO:0003723,GO:0031119,GO:0009451","RNA binding,tRNA pseudouridine synthesis,RNA modification","GO:0003723,GO:0009982,GO:0005634,GO:0001522,GO:0031119,GO:0009451","RNA binding,pseudouridine synthase activity,nucleus,pseudouridine synthesis,tRNA pseudouridine synthesis,RNA modification","."]
["RBM7","RNA binding motif protein 7 [Source:HGNC Symbol;Acc:9904]","ENSG00000076053","ENSP00000364639",1,"RRM_1[1]","family-691","RBM11,RBM7","RBM11","RBM7[28,30]","mRNA","mRNA",21855801,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0007126","nucleotide binding,nucleic acid binding,RNA binding,meiosis","."]
["RBM11","RNA binding motif protein 11 [Source:HGNC Symbol;Acc:9897]","ENSG00000185272","ENSP00000383421",1,"RRM_1[1]","family-691","RBM11,RBM7","RBM11","RBM7[28,30]","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0016607,GO:0030154,GO:0007275,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,nuclear speck,cell differentiation,multicellular organismal development,mRNA processing,RNA splicing","."]
["TSEN2","tRNA splicing endonuclease 2 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28422]","ENSG00000154743","ENSP00000284995",2,"tRNA_int_endo[1],tRNA_int_endo_N[1]","family-692","TSEN2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000213,GO:0000214,GO:0006397,GO:0006388","tRNA-intron endonuclease activity,tRNA-intron endonuclease complex,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation","GO:0003676,GO:0000213,GO:0005634,GO:0005737,GO:0005813,GO:0000214,GO:0006397,GO:0006388","nucleic acid binding,tRNA-intron endonuclease activity,nucleus,cytoplasm,centrosome,tRNA-intron endonuclease complex,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation"," PONTOCEREBELLAR HYPOPLASIA, TYPE 2B; PCH2B"]
["RBM42","RNA binding motif protein 42 [Source:HGNC Symbol;Acc:28117]","ENSG00000126254","ENSP00000466044",1,"RRM_1[1]","family-693","RBM42",".",".","mRNA","putative mRNA","by homology,  19170760",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005737","nucleotide binding,RNA binding,nucleic acid binding,nucleus,cytoplasm","."]
["UTP3","UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24477]","ENSG00000132467","ENSP00000254803",2,"Sas10_Utp3[1],Sas10[1]","family-694","UTP3",".",".","snoRNA","snoRNA/rRNA","established RBP ","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005634,GO:0005730,GO:0007420,GO:0016568","protein binding,nucleus,nucleolus,brain development,chromatin modification","."]
["HNRNPL","heterogeneous nuclear ribonucleoprotein L [Source:HGNC Symbol;Acc:5045]","ENSG00000104824","ENSP00000221419",3,"RRM_5[3]","family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","HNRNPL","HNRNPLL[50,55],PTBP3[23,24],PTBP2[22,25],PTBP1[24,25]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0030529,GO:0008380,GO:0000398,GO:0006396","RNA binding,mRNA processing,ribonucleoprotein complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0003676,GO:0003723,GO:0005634,GO:0006397,GO:0000166,GO:0005515,GO:0044212,GO:0005737,GO:0005654,GO:0030529,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0019013","nucleic acid binding,RNA binding,nucleus,mRNA processing,nucleotide binding,protein binding,transcription regulatory region DNA binding,cytoplasm,nucleoplasm,ribonucleoprotein complex,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,viral nucleocapsid","."]
["HNRNPLL","heterogeneous nuclear ribonucleoprotein L-like [Source:HGNC Symbol;Acc:25127]","ENSG00000143889","ENSP00000386575",3,"RRM_5[2],RRM_6[1]","family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","HNRNPL","HNRNPLL[50,55],PTBP3[23,24],PTBP2[22,25],PTBP1[24,25]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0030529,GO:0003729,GO:0033120","RNA binding,mRNA processing,ribonucleoprotein complex,mRNA binding,positive regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0030529,GO:0019013,GO:0005515,GO:0003729,GO:0033120","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,ribonucleoprotein complex,viral nucleocapsid,protein binding,mRNA binding,positive regulation of RNA splicing","."]
["PTBP1","polypyrimidine tract binding protein 1 [Source:HGNC Symbol;Acc:9583]","ENSG00000011304","ENSP00000349428",4,"RRM_5[3],RRM_6[1]","family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","HNRNPL","HNRNPLL[50,55],PTBP3[23,24],PTBP2[22,25],PTBP1[24,25]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008187,GO:0036002,GO:0008380,GO:0000381,GO:0000398,GO:0000380,GO:0048025,GO:0033119","RNA binding,mRNA processing,poly-pyrimidine tract binding,pre-mRNA binding,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,alternative mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome,negative regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0005515,GO:0008187,GO:0036002,GO:0005730,GO:0005654,GO:0010467,GO:0008380,GO:0000381,GO:0000398,GO:0000380,GO:0048025,GO:0033119,GO:0051148","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,protein binding,poly-pyrimidine tract binding,pre-mRNA binding,nucleolus,nucleoplasm,gene expression,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,alternative mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome,negative regulation of RNA splicing,negative regulation of muscle cell differentiation","."]
["PTBP2","polypyrimidine tract binding protein 2 [Source:HGNC Symbol;Acc:17662]","ENSG00000117569","ENSP00000359217",4,"RRM_5[3],RRM_6[1]","family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","HNRNPL","HNRNPLL[50,55],PTBP3[23,24],PTBP2[22,25],PTBP1[24,25]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0003729,GO:0005681,GO:0006376,GO:0033119","RNA binding,mRNA processing,mRNA binding,spliceosomal complex,mRNA splice site selection,negative regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0005515,GO:0003729,GO:0005681,GO:0006376,GO:2000177,GO:0033119","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,protein binding,mRNA binding,spliceosomal complex,mRNA splice site selection,regulation of neural precursor cell proliferation,negative regulation of RNA splicing","."]
["PTBP3","polypyrimidine tract binding protein 3 [Source:HGNC Symbol;Acc:10253]","ENSG00000119314","ENSP00000414921",4,"RRM_5[2],RRM_1[1],RRM_6[1]","family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","HNRNPL","HNRNPLL[50,55],PTBP3[23,24],PTBP2[22,25],PTBP1[24,25]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0033119","RNA binding,mRNA processing,RNA splicing,negative regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006397,GO:0008380,GO:0045595,GO:0043249,GO:0009653,GO:0033119","nucleotide binding,RNA binding,nucleic acid binding,nucleus,mRNA processing,RNA splicing,regulation of cell differentiation,erythrocyte maturation,anatomical structure morphogenesis,negative regulation of RNA splicing","."]
["SYMPK","symplekin [Source:HGNC Symbol;Acc:22935]","ENSG00000125755","ENSP00000245934",3,"DUF3453[1],Cohesin_HEAT[1],Symplekin_C[1]","family-696","SYMPK",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0006398,GO:0006378","histone mRNA 3'-end processing,mRNA polyadenylation","GO:0005488,GO:0006398,GO:0005515,GO:0005634,GO:0005886,GO:0005737,GO:0005923,GO:0005856,GO:0005654,GO:0007155,GO:0006378,GO:0035307","binding,histone mRNA 3'-end processing,protein binding,nucleus,plasma membrane,cytoplasm,tight junction,cytoskeleton,nucleoplasm,cell adhesion,mRNA polyadenylation,positive regulation of protein dephosphorylation","."]
["POLR2F","polymerase (RNA) II (DNA directed) polypeptide F [Source:HGNC Symbol;Acc:9193]","ENSG00000100142","ENSP00000403852",1,"RNA_pol_Rpb6[1]","family-697","POLR2F",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003677,GO:0003899,GO:0005665,GO:0006351,GO:0001055,GO:0001056,GO:0001054,GO:0005634,GO:0005829,GO:0005730,GO:0005654,GO:0005736,GO:0005666,GO:0045087,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0006383,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006360,GO:0006370,GO:0032481,GO:0006283,GO:0050434,GO:0006385,GO:0006386","DNA binding,DNA-directed RNA polymerase activity,DNA-directed RNA polymerase II, core complex,transcription, DNA-templated,RNA polymerase II activity,RNA polymerase III activity,RNA polymerase I activity,nucleus,cytosol,nucleolus,nucleoplasm,DNA-directed RNA polymerase I complex,DNA-directed RNA polymerase III complex,innate immune response,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,transcription from RNA polymerase III promoter,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,transcription from RNA polymerase I promoter,7-methylguanosine mRNA capping,positive regulation of type I interferon production,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription,transcription elongation from RNA polymerase III promoter,termination of RNA polymerase III transcription","."]
["TSR2","TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25455]","ENSG00000158526","ENSP00000364293",1,"WGG[1]","family-698","TSR2",".",".","rRNA","rRNA","by homology",".",".",".",".",".",".","GO:0006364","rRNA processing","GO:0005515,GO:0006364","protein binding,rRNA processing","."]
["KIAA0391","mitochondrial ribonuclease P protein 3 isoform 4  [Source:RefSeq peptide;Acc:NP_001243609]","ENSG00000100890","ENSP00000450898",1,"RNase_Zc3h12a[1]","family-699","KIAA0391",".",".","ncRNA","MRP RNA","MRPP3 yeast homolog, 18984158",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0005739,GO:0008033","mitochondrion,tRNA processing","."]
["POLR2G","polymerase (RNA) II (DNA directed) polypeptide G [Source:HGNC Symbol;Acc:9194]","ENSG00000168002","ENSP00000301788",2,"S1[1],SHS2_Rpb7-N[1]","family-7","POLR2G",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0003723,GO:0008380,GO:0000398,GO:0006370","RNA binding,RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0003899,GO:0006351,GO:0006915,GO:0003723,GO:0005634,GO:0005654,GO:0005665,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006370,GO:0006283,GO:0050434","DNA-directed RNA polymerase activity,transcription, DNA-templated,apoptotic process,RNA binding,nucleus,nucleoplasm,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription","."]
["WDR5","WD repeat domain 5 [Source:HGNC Symbol;Acc:12757]","ENSG00000196363","ENSP00000351446",7,"WD40[7]","family-70","ATG16L1,WDR38,DAW1,WDR5,WDR5B,ATG16L2,SNRNP40,WDR83","ATG16L1","WDR38[11,22],DAW1[14,20],WDR5[12,22],WDR5B[13,24],ATG16L2[39,38],SNRNP40[16,27],WDR83[10,19]","ncRNA","lincRNA",21423168,".",".",".",".",".",".",".",".","GO:0005515,GO:0042800,GO:0043995,GO:0043996,GO:0046972,GO:0000123,GO:0005634,GO:0035097,GO:0005671,GO:0071339,GO:0048188,GO:0006351,GO:0001501,GO:0006355,GO:0051568,GO:0043984,GO:0043966,GO:0043981,GO:0043982,GO:0005622","protein binding,histone methyltransferase activity (H3-K4 specific),histone acetyltransferase activity (H4-K5 specific),histone acetyltransferase activity (H4-K8 specific),histone acetyltransferase activity (H4-K16 specific),histone acetyltransferase complex,nucleus,histone methyltransferase complex,Ada2/Gcn5/Ada3 transcription activator complex,MLL1 complex,Set1C/COMPASS complex,transcription, DNA-templated,skeletal system development,regulation of transcription, DNA-dependent,histone H3-K4 methylation,histone H4-K16 acetylation,histone H3 acetylation,histone H4-K5 acetylation,histone H4-K8 acetylation,intracellular","."]
["SNRNP40","small nuclear ribonucleoprotein 40kDa (U5) [Source:HGNC Symbol;Acc:30857]","ENSG00000060688","ENSP00000263694",7,"WD40[7]","family-70","ATG16L1,WDR38,DAW1,WDR5,WDR5B,ATG16L2,SNRNP40,WDR83","ATG16L1","WDR38[11,22],DAW1[14,20],WDR5[12,22],WDR5B[13,24],ATG16L2[39,38],SNRNP40[16,27],WDR83[10,19]","snRNA","snRNA","established RBP ",".","RNArelated",".",1,".",".","GO:0005732,GO:0071013,GO:0005682,GO:0008380,GO:0000398,GO:0006396,GO:0000375","small nucleolar ribonucleoprotein complex,catalytic step 2 spliceosome,U5 snRNP,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA splicing, via transesterification reactions","GO:0005515,GO:0005634,GO:0005737,GO:0005654,GO:0005732,GO:0071013,GO:0005682,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0000375","protein binding,nucleus,cytoplasm,nucleoplasm,small nucleolar ribonucleoprotein complex,catalytic step 2 spliceosome,U5 snRNP,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA splicing, via transesterification reactions","."]
["WDR83","WD repeat domain 83 [Source:HGNC Symbol;Acc:32672]","ENSG00000123154","ENSP00000402653",3,"WD40[3]","family-70","ATG16L1,WDR38,DAW1,WDR5,WDR5B,ATG16L2,SNRNP40,WDR83","ATG16L1","WDR38[11,22],DAW1[14,20],WDR5[12,22],WDR5B[13,24],ATG16L2[39,38],SNRNP40[16,27],WDR83[10,19]","mRNA","putative mRNA","This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]",".",".",".",".",".",".","GO:0005681,GO:0071013,GO:0000398,GO:0000375","spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0005515,GO:0005737,GO:0005681,GO:0071013,GO:0000398,GO:0000375,GO:0016301","protein binding,cytoplasm,spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,kinase activity","."]
["ZFC3H1","zinc finger, C3H1-type containing [Source:HGNC Symbol;Acc:28328]","ENSG00000133858","ENSP00000368017",3,"TPR_19[2],zf-C3H1[1]","family-700","ZFC3H1",".",".","unknown","unknown","established RBP ",".","RNArelated",".",1,".",".","GO:0006396","RNA processing","GO:0005515,GO:0046872,GO:0005622,GO:0006396","protein binding,metal ion binding,intracellular,RNA processing","."]
["RPL15","ribosomal protein L15 [Source:HGNC Symbol;Acc:10306]","ENSG00000174748","ENSP00000387925",1,"Ribosomal_L15e[1]","family-701","RPL15",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["SNRNP35","small nuclear ribonucleoprotein 35kDa (U11/U12) [Source:HGNC Symbol;Acc:30852]","ENSG00000184209","ENSP00000432595",1,"RRM_1[1]","family-702","SNRNP35,SNRNP70","SNRNP35","SNRNP70[41,24]","snRNA","snRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0005689,GO:0006397,GO:0008380","RNA binding,U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005689,GO:0006397,GO:0008380","nucleotide binding,RNA binding,nucleic acid binding,nucleus,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["SNRNP70","small nuclear ribonucleoprotein 70kDa (U1) [Source:HGNC Symbol;Acc:11150]","ENSG00000104852","ENSP00000472998",2,"RRM_1[1],U1snRNP70_N[1]","family-702","SNRNP35,SNRNP70","SNRNP35","SNRNP70[41,24]","snRNA","snRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380,GO:0000398,GO:0043484","RNA binding,spliceosomal complex,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,regulation of RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005654,GO:0005681,GO:0016607,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0043484","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,nucleoplasm,spliceosomal complex,nuclear speck,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,regulation of RNA splicing","."]
["MRPL39","mitochondrial ribosomal protein L39 [Source:HGNC Symbol;Acc:14027]","ENSG00000154719","ENSP00000305682",1,"TGS[1]","family-703","MRPL39",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0005761","mitochondrial ribosome","GO:0000166,GO:0005739,GO:0005761","nucleotide binding,mitochondrion,mitochondrial ribosome","."]
["TLR7","toll-like receptor 7 [Source:HGNC Symbol;Acc:15631] [Type: protein coding Ensembl/Havana merge]","ENSG00000196664","ENSP00000370034",9,"TIR[1],LRR_8[7],LRR_4[1]","family-704","TLR3,TLR4,TLR5,TLR7,TLR8,TLR9,CD180","TLR3","TLR4[22,24],TLR5[23,24],TLR7[25,22],TLR8[26,22],TLR9[24,21],CD180[17,23]","ncRNA","viral RNA",16111635,".",".",".",".",".",".","GO:0003727,GO:0035197,GO:0003725","single-stranded RNA binding,siRNA binding,double-stranded RNA binding","GO:0003727,GO:0035197,GO:0005515,GO:0003725,GO:0004888,GO:0008144,GO:0005783,GO:0005764,GO:0005768,GO:0032009,GO:0016021,GO:0005886,GO:0005737,GO:0005789,GO:0000139,GO:0010008,GO:0036020,GO:0002224,GO:0045087,GO:0006954,GO:0050729,GO:0007165,GO:0051607,GO:0032755,GO:0071260,GO:0002282,GO:0002755,GO:0032722,GO:0042346,GO:0042221,GO:0052033,GO:0045359,GO:0007252,GO:0034162,GO:0045078,GO:0032757,GO:0045416,GO:0045356,GO:0034154","single-stranded RNA binding,siRNA binding,protein binding,double-stranded RNA binding,transmembrane signaling receptor activity,drug binding,endoplasmic reticulum,lysosome,endosome,early phagosome,integral to membrane,plasma membrane,cytoplasm,endoplasmic reticulum membrane,Golgi membrane,endosome membrane,endolysosome membrane,toll-like receptor signaling pathway,innate immune response,inflammatory response,positive regulation of inflammatory response,signal transduction,defense response to virus,positive regulation of interleukin-6 production,cellular response to mechanical stimulus,microglial cell activation involved in immune response,MyD88-dependent toll-like receptor signaling pathway,positive regulation of chemokine production,positive regulation of NF-kappaB import into nucleus,response to chemical,pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response,positive regulation of interferon-beta biosynthetic process,I-kappaB phosphorylation,toll-like receptor 9 signaling pathway,positive regulation of interferon-gamma biosynthetic process,positive regulation of interleukin-8 production,positive regulation of interleukin-8 biosynthetic process,positive regulation of interferon-alpha biosynthetic process,toll-like receptor 7 signaling pathway","."]
["TLR8","toll-like receptor 8 [Source:HGNC Symbol;Acc:15632]","ENSG00000101916","ENSP00000218032",9,"TIR[1],LRR_8[6],LRR_4[2]","family-704","TLR3,TLR4,TLR5,TLR7,TLR8,TLR9,CD180","TLR3","TLR4[22,24],TLR5[23,24],TLR7[25,22],TLR8[26,22],TLR9[24,21],CD180[17,23]","ncRNA","viral RNA",16111635,".",".",".",".",".",".","GO:0003723,GO:0003725,GO:0003727","RNA binding,double-stranded RNA binding,single-stranded RNA binding","GO:0003723,GO:0005515,GO:0003677,GO:0003725,GO:0003727,GO:0004872,GO:0016021,GO:0005789,GO:0000139,GO:0010008,GO:0036020,GO:0045087,GO:0006954,GO:0009615,GO:0007165,GO:0002224,GO:0051607,GO:0016064,GO:0007249,GO:0071260,GO:0002755,GO:0050707,GO:0045359,GO:0034162,GO:0045078,GO:0045416,GO:0045089,GO:0045356,GO:0034158,GO:0008144,GO:0002282,GO:0052033","RNA binding,protein binding,DNA binding,double-stranded RNA binding,single-stranded RNA binding,receptor activity,integral to membrane,endoplasmic reticulum membrane,Golgi membrane,endosome membrane,endolysosome membrane,innate immune response,inflammatory response,response to virus,signal transduction,toll-like receptor signaling pathway,defense response to virus,immunoglobulin mediated immune response,I-kappaB kinase/NF-kappaB signaling,cellular response to mechanical stimulus,MyD88-dependent toll-like receptor signaling pathway,regulation of cytokine secretion,positive regulation of interferon-beta biosynthetic process,toll-like receptor 9 signaling pathway,positive regulation of interferon-gamma biosynthetic process,positive regulation of interleukin-8 biosynthetic process,positive regulation of innate immune response,positive regulation of interferon-alpha biosynthetic process,toll-like receptor 8 signaling pathway,drug binding,microglial cell activation involved in immune response,pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response","."]
["TLR3","toll-like receptor 3 [Source:HGNC Symbol;Acc:11849] [Type: protein coding Ensembl/Havana merge]","ENSG00000164342","ENSP00000296795",9,"TIR[1],LRR_8[7],LRRNT[1]","family-704","TLR3,TLR4,TLR5,TLR7,TLR8,TLR9,CD180","TLR3","TLR4[22,24],TLR5[23,24],TLR7[25,22],TLR8[26,22],TLR9[24,21],CD180[17,23]","ncRNA","viral RNA","This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003725,GO:0043330,GO:0071360,GO:0071359,GO:0043331","double-stranded RNA binding,response to exogenous dsRNA,cellular response to exogenous dsRNA,cellular response to dsRNA,response to dsRNA","GO:0005515,GO:0003725,GO:0004888,GO:0016021,GO:0045944,GO:0045087,GO:0043123,GO:0050729,GO:0032728,GO:0043330,GO:0007165,GO:0046330,GO:0051092,GO:0051607,GO:0032755,GO:0032760,GO:0045080,GO:0002756,GO:0032722,GO:0034138,GO:0032735,GO:0034346,GO:0004872,GO:0005622,GO:0009986,GO:0005737,GO:0005887,GO:0005789,GO:0016020,GO:0000139,GO:0010008,GO:0005765,GO:0036020,GO:0006952,GO:0032481,GO:0052033,GO:0002282,GO:0002224,GO:0009615,GO:0043065,GO:0001934,GO:0071360,GO:0071359,GO:0071346,GO:0035690,GO:0035458,GO:0043331,GO:0008584,GO:0006954,GO:0042742,GO:0045671,GO:0007250,GO:0007249,GO:0071260,GO:0042346,GO:0006972,GO:0045359,GO:0007252,GO:0034142,GO:0045078,GO:0032757,GO:0035666,GO:0097191,GO:0009597,GO:0034123,GO:0045356,GO:0097527","protein binding,double-stranded RNA binding,transmembrane signaling receptor activity,integral to membrane,positive regulation of transcription from RNA polymerase II promoter,innate immune response,positive regulation of I-kappaB kinase/NF-kappaB signaling,positive regulation of inflammatory response,positive regulation of interferon-beta production,response to exogenous dsRNA,signal transduction,positive regulation of JNK cascade,positive regulation of NF-kappaB transcription factor activity,defense response to virus,positive regulation of interleukin-6 production,positive regulation of tumor necrosis factor production,positive regulation of chemokine biosynthetic process,MyD88-independent toll-like receptor signaling pathway,positive regulation of chemokine production,toll-like receptor 3 signaling pathway,positive regulation of interleukin-12 production,positive regulation of type III interferon production,receptor activity,intracellular,cell surface,cytoplasm,integral to plasma membrane,endoplasmic reticulum membrane,membrane,Golgi membrane,endosome membrane,lysosomal membrane,endolysosome membrane,defense response,positive regulation of type I interferon production,pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response,microglial cell activation involved in immune response,toll-like receptor signaling pathway,response to virus,positive regulation of apoptotic process,positive regulation of protein phosphorylation,cellular response to exogenous dsRNA,cellular response to dsRNA,cellular response to interferon-gamma,cellular response to drug,cellular response to interferon-beta,response to dsRNA,male gonad development,inflammatory response,defense response to bacterium,negative regulation of osteoclast differentiation,activation of NF-kappaB-inducing kinase activity,I-kappaB kinase/NF-kappaB signaling,cellular response to mechanical stimulus,positive regulation of NF-kappaB import into nucleus,hyperosmotic response,positive regulation of interferon-beta biosynthetic process,I-kappaB phosphorylation,toll-like receptor 4 signaling pathway,positive regulation of interferon-gamma biosynthetic process,positive regulation of interleukin-8 production,TRIF-dependent toll-like receptor signaling pathway,extrinsic apoptotic signaling pathway,detection of virus,positive regulation of toll-like receptor signaling pathway,positive regulation of interferon-alpha biosynthetic process,necroptotic signaling pathway"," HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 2"]
["NAA38","N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:20471]","ENSG00000128534","ENSP00000403811",1,"LSM[1]","family-705","NAA38",".",".","snoRNA","snoRNA","Previous names: LSM8 homolog, U6 small nuclear RNA associated","RNAbinding","RNAbinding",1,1,1,1,"GO:0017070,GO:0005681,GO:0000398","U6 snRNA binding,spliceosomal complex,mRNA splicing, via spliceosome","GO:0005515,GO:0017070,GO:0005634,GO:0005681,GO:0000398","protein binding,U6 snRNA binding,nucleus,spliceosomal complex,mRNA splicing, via spliceosome","."]
["PRPF31","PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15446]","ENSG00000105618","ENSP00000324122",3,"Nop[1],Prp31_C[1],NOSIC[1]","family-706","PRPF31",".",".","snRNA","snRNA/mRNA",11867543,"RNAbinding","experimentally validated",1,1,1,".","GO:0046540,GO:0003723,GO:0043021,GO:0070990,GO:0005687,GO:0005684,GO:0005690,GO:0000398","U4/U6 x U5 tri-snRNP complex,RNA binding,ribonucleoprotein complex binding,snRNP binding,U4 snRNP,U2-type spliceosomal complex,U4atac snRNP,mRNA splicing, via spliceosome","GO:0046540,GO:0000244,GO:0003723,GO:0005515,GO:0043021,GO:0070990,GO:0005634,GO:0016607,GO:0071339,GO:0015030,GO:0005687,GO:0005684,GO:0005690,GO:0000398","U4/U6 x U5 tri-snRNP complex,spliceosomal tri-snRNP complex assembly,RNA binding,protein binding,ribonucleoprotein complex binding,snRNP binding,nucleus,nuclear speck,MLL1 complex,Cajal body,U4 snRNP,U2-type spliceosomal complex,U4atac snRNP,mRNA splicing, via spliceosome"," RETINITIS PIGMENTOSA 11; RP11"]
["MRPL55","mitochondrial ribosomal protein L55 [Source:HGNC Symbol;Acc:16686]","ENSG00000162910","ENSP00000337342",1,"Mitoc_L55[1]","family-707","MRPL55",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005762,GO:0006412","structural constituent of ribosome,mitochondrial large ribosomal subunit,translation","GO:0003735,GO:0005762,GO:0006412,GO:0005739","structural constituent of ribosome,mitochondrial large ribosomal subunit,translation,mitochondrion","."]
["TRMT2A","tRNA methyltransferase 2 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:24974]","ENSG00000099899","ENSP00000252136",2,"tRNA_U5-meth_tr[1],RRM_6[1]","family-708","TRMT2A,TRMT2B","TRMT2A","TRMT2B[29,37]","tRNA","putative tRNA","The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]",".","RNAbinding",".",1,1,1,"GO:0008173,GO:0006396,GO:0003723,GO:0008176,GO:0006400,GO:0031167","RNA methyltransferase activity,RNA processing,RNA binding,tRNA (guanine-N7-)-methyltransferase activity,tRNA modification,rRNA methylation","GO:0000166,GO:0003676,GO:0008173,GO:0006396,GO:0003723,GO:0008168,GO:0004719,GO:0008176,GO:0006464,GO:0008152,GO:0006400,GO:0031167","nucleotide binding,nucleic acid binding,RNA methyltransferase activity,RNA processing,RNA binding,methyltransferase activity,protein-L-isoaspartate (D-aspartate) O-methyltransferase activity,tRNA (guanine-N7-)-methyltransferase activity,cellular protein modification process,metabolic process,tRNA modification,rRNA methylation","."]
["TRMT2B","tRNA methyltransferase 2 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25748]","ENSG00000188917","ENSP00000362027",1,"Methyltransf_31[1]","family-708","TRMT2A,TRMT2B","TRMT2A","TRMT2B[29,37]","tRNA","putative tRNA","This gene encodes a homolog of the TRM2 gene in S. cerevisiae. The yeast gene encodes a tRNA methyltransferase that plays a role in tRNA maturation. The yeast protein also has endo-exonuclease activity and may be involved in DNA double strand break repair. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Nov 2009]",".",".",".",".",".",".","GO:0008173,GO:0006396,GO:0030697","RNA methyltransferase activity,RNA processing,S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity","GO:0008168,GO:0008173,GO:0006396,GO:0030697,GO:0005739","methyltransferase activity,RNA methyltransferase activity,RNA processing,S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity,mitochondrion","."]
["RPS3A","ribosomal protein S3A [Source:HGNC Symbol;Acc:10421]","ENSG00000145425","ENSP00000426466",1,"Ribosomal_S3Ae[1]","family-709","RPS3A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0022627,GO:0005840,GO:0006412,GO:0003723,GO:0030529,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,translation,RNA binding,ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005634,GO:0005622,GO:0022627,GO:0005840,GO:0030154,GO:0006412,GO:0003723,GO:0005515,GO:0005737,GO:0005829,GO:0005730,GO:0030529,GO:0043066,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0002181","structural constituent of ribosome,nucleus,intracellular,cytosolic small ribosomal subunit,ribosome,cell differentiation,translation,RNA binding,protein binding,cytoplasm,cytosol,nucleolus,ribonucleoprotein complex,negative regulation of apoptotic process,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,cytoplasmic translation","."]
["BRCA1","breast cancer 1, early onset [Source:HGNC Symbol;Acc:1100]","ENSG00000012048","ENSP00000418960",5,"BRCT[2],EIN3[1],zf-C3HC4[1],BRCT_assoc[1]","family-71","BRCA1",".",".","ncRNA","lincRNA ",12419249,".",".",".",".",".",".","GO:0003723,GO:0030529,GO:0070531,GO:0031436","RNA binding,ribonucleoprotein complex,BRCA1-A complex,BRCA1-BARD1 complex","GO:0008270,GO:0003677,GO:0004842,GO:0003684,GO:0044212,GO:0005634,GO:0005737,GO:0000794,GO:0045944,GO:0006281,GO:0006260,GO:0006349,GO:0007098,GO:0009048,GO:0035067,GO:0043009,GO:0044030,GO:0051571,GO:0051572,GO:0051573,GO:0051574,GO:0070512,GO:2000617,GO:2000620,GO:0005515,GO:0046872,GO:0003723,GO:0031625,GO:0019899,GO:0003713,GO:0015631,GO:0050681,GO:0005886,GO:0005694,GO:0001726,GO:0005654,GO:0043234,GO:0030529,GO:0005925,GO:0031941,GO:0000151,GO:0070531,GO:0008274,GO:0031436,GO:0016567,GO:0006915,GO:0045893,GO:0042981,GO:0006974,GO:0045892,GO:0042127,GO:0006357,GO:0031398,GO:0006633,GO:0045717,GO:0008630,GO:0043627,GO:0051865,GO:0006302,GO:0010212,GO:0000724,GO:0006301,GO:0034446,GO:0030521,GO:0035066,GO:0007059,GO:2000145,GO:0046600,GO:0085020,GO:0006978,GO:0031572,GO:0045739,GO:0071158,GO:0006359,GO:0071681,GO:0000793","zinc ion binding,DNA binding,ubiquitin-protein ligase activity,damaged DNA binding,transcription regulatory region DNA binding,nucleus,cytoplasm,condensed nuclear chromosome,positive regulation of transcription from RNA polymerase II promoter,DNA repair,DNA replication,regulation of gene expression by genetic imprinting,centrosome cycle,dosage compensation by inactivation of X chromosome,negative regulation of histone acetylation,chordate embryonic development,regulation of DNA methylation,positive regulation of histone H3-K4 methylation,negative regulation of histone H3-K4 methylation,negative regulation of histone H3-K9 methylation,positive regulation of histone H3-K9 methylation,positive regulation of histone H4-K20 methylation,positive regulation of histone H3-K9 acetylation,positive regulation of histone H4-K16 acetylation,protein binding,metal ion binding,RNA binding,ubiquitin protein ligase binding,enzyme binding,transcription coactivator activity,tubulin binding,androgen receptor binding,plasma membrane,chromosome,ruffle,nucleoplasm,protein complex,ribonucleoprotein complex,focal adhesion,filamentous actin,ubiquitin ligase complex,BRCA1-A complex,gamma-tubulin ring complex,BRCA1-BARD1 complex,protein ubiquitination,apoptotic process,positive regulation of transcription, DNA-dependent,regulation of apoptotic process,cellular response to DNA damage stimulus,negative regulation of transcription, DNA-dependent,regulation of cell proliferation,regulation of transcription from RNA polymerase II promoter,positive regulation of protein ubiquitination,fatty acid biosynthetic process,negative regulation of fatty acid biosynthetic process,intrinsic apoptotic signaling pathway in response to DNA damage,response to estrogen,protein autoubiquitination,double-strand break repair,response to ionizing radiation,double-strand break repair via homologous recombination,postreplication repair,substrate adhesion-dependent cell spreading,androgen receptor signaling pathway,positive regulation of histone acetylation,chromosome segregation,regulation of cell motility,negative regulation of centriole replication,protein K6-linked ubiquitination,DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,G2 DNA damage checkpoint,positive regulation of DNA repair,positive regulation of cell cycle arrest,regulation of transcription from RNA polymerase III promoter,cellular response to indole-3-methanol,condensed chromosome"," BREAST CANCER"]
["RIOK2","RIO kinase 2 [Source:HGNC Symbol;Acc:18999]","ENSG00000058729","ENSP00000283109",2,"Rio2_N[1],RIO1[1]","family-710","RIOK2",".",".","rRNA","rRNA",19564402,".",".",".",".",".",".",".",".","GO:0005524,GO:0004674,GO:0003824,GO:0016773,GO:0016772,GO:0016020,GO:0006468,GO:0009103","ATP binding,protein serine/threonine kinase activity,catalytic activity,phosphotransferase activity, alcohol group as acceptor,transferase activity, transferring phosphorus-containing groups,membrane,protein phosphorylation,lipopolysaccharide biosynthetic process","."]
["DHX16","DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Source:HGNC Symbol;Acc:2739]","ENSG00000206486","ENSP00000373071",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","snRNA","snRNA","20423332, PRP8 yeast homolog","helicase","RNArelated",1,1,".",".","GO:0003724,GO:0006397,GO:0008380","RNA helicase activity,mRNA processing,RNA splicing","GO:0005515,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003724,GO:0005634,GO:0006397,GO:0008380","protein binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA helicase activity,nucleus,mRNA processing,RNA splicing","."]
["DHX33","DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Source:HGNC Symbol;Acc:16718]","ENSG00000005100","ENSP00000458925",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","mRNA, rRNA","by homology",".","novel",".",1,1,".",".",".","GO:0005524,GO:0003676,GO:0004386,GO:0000182,GO:0008026,GO:0033613,GO:0005730,GO:0005654,GO:0045943","ATP binding,nucleic acid binding,helicase activity,rDNA binding,ATP-dependent helicase activity,activating transcription factor binding,nucleolus,nucleoplasm,positive regulation of transcription from RNA polymerase I promoter","."]
["DHX35","DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Source:HGNC Symbol;Acc:15861]","ENSG00000101452","ENSP00000252011",4,"OB_NTP_bind[1],HA2[1],Helicase_C[1],DEAD[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","mRNA","by homology",".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0071013,GO:0000398","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["DHX32","DEAH (Asp-Glu-Ala-His) box polypeptide 32 [Source:HGNC Symbol;Acc:16717]","ENSG00000089876","ENSP00000284688",2,"OB_NTP_bind[1],HA2[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","mRNA","PRP43 yeast homolog",".",".",".",".",".",".",".",".","GO:0005524,GO:0004386,GO:0005634,GO:0005739","ATP binding,helicase activity,nucleus,mitochondrion","."]
["DQX1","DEAQ box RNA-dependent ATPase 1 [Source:HGNC Symbol;Acc:20410]","ENSG00000144045","ENSP00000377523",3,"OB_NTP_bind[1],HA2[1],AAA_22[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","putative mRNA","PRP43 yeast homolog",".",".",".",".",".",".",".",".","GO:0005524,GO:0003676,GO:0004386,GO:0005634","ATP binding,nucleic acid binding,helicase activity,nucleus","."]
["DHX15","DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Source:HGNC Symbol;Acc:2738]","ENSG00000109606","ENSP00000336741",5,"OB_NTP_bind[1],DUF1777[1],HA2[1],Helicase_C[1],DEAD[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","mRNA","The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. [provided by RefSeq, Jul 2008]","helicase","RNArelated",1,1,1,".","GO:0003725,GO:0003724,GO:0005689,GO:0006397,GO:0008380","double-stranded RNA binding,RNA helicase activity,U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0005515,GO:0005524,GO:0003676,GO:0003725,GO:0008026,GO:0004386,GO:0003724,GO:0005634,GO:0005730,GO:0005689,GO:0006397,GO:0008380","protein binding,ATP binding,nucleic acid binding,double-stranded RNA binding,ATP-dependent helicase activity,helicase activity,RNA helicase activity,nucleus,nucleolus,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["DHX8","DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Source:HGNC Symbol;Acc:2749]","ENSG00000067596","ENSP00000262415",4,"OB_NTP_bind[1],S1[1],Helicase_C[1],DEAD[1]","family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","DHX15","DHX33[35,39],DHX8[46,30],DHX35[38,43],DHX32[36,38],DHX16[46,35],DQX1[33,36]","mRNA","mRNA","This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq, Jul 2008]","helicase","RNAbinding",1,1,".",1,"GO:0003723,GO:0004004,GO:0005681,GO:0071013,GO:0008380,GO:0000398,GO:0006396","RNA binding,ATP-dependent RNA helicase activity,spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0008026,GO:0042802,GO:0004386,GO:0004004,GO:0005634,GO:0005681,GO:0071013,GO:0008380,GO:0000398,GO:0006396,GO:0006810","RNA binding,protein binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,identical protein binding,helicase activity,ATP-dependent RNA helicase activity,nucleus,spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA processing,transport","."]
["MRPS5","mitochondrial ribosomal protein S5 [Source:HGNC Symbol;Acc:14498]","ENSG00000144029","ENSP00000272418",2,"Ribosomal_S5[1],Ribosomal_S5_C[1]","family-712","MRPS5",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0005840,GO:0006412","RNA binding,structural constituent of ribosome,ribosome,translation","GO:0003723,GO:0003735,GO:0005739,GO:0005840,GO:0006412","RNA binding,structural constituent of ribosome,mitochondrion,ribosome,translation","."]
["SAP18","Sin3A-associated protein, 18kDa [Source:HGNC Symbol;Acc:10530]","ENSG00000150459","ENSP00000391846",1,"SAP18[1]","family-713","SAP18",".",".","mRNA","putative mRNA",22388736,"candidate mRNA binder",".",".",1,1,".","GO:0006397,GO:0008380,GO:0000381,GO:0048025","mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,negative regulation of mRNA splicing, via spliceosome","GO:0003714,GO:0005515,GO:0005634,GO:0005886,GO:0005737,GO:0000118,GO:0016607,GO:0035145,GO:0061574,GO:0006351,GO:0006397,GO:0008380,GO:0000381,GO:0006357,GO:0043065,GO:0048025","transcription corepressor activity,protein binding,nucleus,plasma membrane,cytoplasm,histone deacetylase complex,nuclear speck,exon-exon junction complex,ASAP complex,transcription, DNA-templated,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,regulation of transcription from RNA polymerase II promoter,positive regulation of apoptotic process,negative regulation of mRNA splicing, via spliceosome","."]
["TUFM","Tu translation elongation factor, mitochondrial [Source:HGNC Symbol;Acc:12420]","ENSG00000178952","ENSP00000322439",3,"GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-714","EEFSEC,TUFM","EEFSEC","TUFM[18,24]","mRNA","mRNA",19524667,".","novel",".",1,".",".","GO:0003746,GO:0006414","translation elongation factor activity,translational elongation","GO:0005525,GO:0003924,GO:0003746,GO:0005739,GO:0005622,GO:0042645,GO:0006414","GTP binding,GTPase activity,translation elongation factor activity,mitochondrion,intracellular,mitochondrial nucleoid,translational elongation"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 4; COXPD4"]
["EEFSEC","eukaryotic elongation factor, selenocysteine-tRNA-specific [Source:HGNC Symbol;Acc:24614]","ENSG00000132394","ENSP00000254730",2,"GTP_EFTU_D2[1],GTP_EFTU[1]","family-714","EEFSEC,TUFM","EEFSEC","TUFM[18,24]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0003746,GO:0043021,GO:0000049,GO:0030529,GO:0006414","translation elongation factor activity,ribonucleoprotein complex binding,tRNA binding,ribonucleoprotein complex,translational elongation","GO:0005525,GO:0003924,GO:0005515,GO:0003746,GO:0043021,GO:0035368,GO:0000049,GO:0030529,GO:0005634,GO:0005737,GO:0005739,GO:0006184,GO:0006414,GO:0001514","GTP binding,GTPase activity,protein binding,translation elongation factor activity,ribonucleoprotein complex binding,selenocysteine insertion sequence binding,tRNA binding,ribonucleoprotein complex,nucleus,cytoplasm,mitochondrion,GTP catabolic process,translational elongation,selenocysteine incorporation","."]
["TDRD12","tudor domain containing 12 [Source:HGNC Symbol;Acc:25044]","ENSG00000173809","ENSP00000416248",3,"TUDOR[2],DEAD[1]","family-715","TDRD12",".",".","ncRNA","piRNA related",24067652,".",".",".",".",".",".","GO:0031047,GO:0034587","gene silencing by RNA,piRNA metabolic process","GO:0005524,GO:0003676,GO:0008026,GO:0007283,GO:0007140,GO:0009566,GO:0031047,GO:0034587,GO:0043046","ATP binding,nucleic acid binding,ATP-dependent helicase activity,spermatogenesis,male meiosis,fertilization,gene silencing by RNA,piRNA metabolic process,DNA methylation involved in gamete generation","."]
["SKIV2L2","superkiller viralicidic activity 2-like 2 (S. cerevisiae) [Source:HGNC Symbol;Acc:18734]","ENSG00000039123","ENSP00000230640",4,"Helicase_C[1],rRNA_proc-arch[1],DSHCT[1],DEAD[1]","family-716","SKIV2L2",".",".","diverse","diverse",11719186,".","RNArelated",".",1,1,".","GO:0000178,GO:0071013,GO:0000398,GO:0000460","exosome (RNase complex),catalytic step 2 spliceosome,mRNA splicing, via spliceosome,maturation of 5.8S rRNA","GO:0005524,GO:0003676,GO:0016817,GO:0008026,GO:0004386,GO:0016818,GO:0005634,GO:0005515,GO:0005730,GO:0000178,GO:0071013,GO:0000398,GO:0000460","ATP binding,nucleic acid binding,hydrolase activity, acting on acid anhydrides,ATP-dependent helicase activity,helicase activity,hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides,nucleus,protein binding,nucleolus,exosome (RNase complex),catalytic step 2 spliceosome,mRNA splicing, via spliceosome,maturation of 5.8S rRNA","."]
["TRDMT1","tRNA aspartic acid methyltransferase 1 [Source:HGNC Symbol;Acc:2977]","ENSG00000107614","ENSP00000367030",1,"DNA_methylase[1]","family-717","TRDMT1",".",".","tRNA","tRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0008033","RNA binding,tRNA processing","GO:0003723,GO:0003677,GO:0008168,GO:0003886,GO:0005634,GO:0008033,GO:0006306,GO:0001975,GO:0090116","RNA binding,DNA binding,methyltransferase activity,DNA (cytosine-5-)-methyltransferase activity,nucleus,tRNA processing,DNA methylation,response to amphetamine,C-5 methylation of cytosine","."]
["ZNF473","zinc finger protein 473 [Source:HGNC Symbol;Acc:23239]","ENSG00000142528","ENSP00000472808",18,"zf-C2H2_4[1],KRAB[1],zf-H2C2_2[13],zf-C2H2[3]","family-718","ZFP62,ZNF814,ZNF629,ZNF347,ZNF836,ZNF473,ZNF268,ZNF845,ZNF585A,ZNF160,ZNF658,ZNF197,ZNF841,ZNF616,ZNF585B,ZNF808,ZNF107,ZNF99,ZNF43,ZNF721,ZNF493,ZNF780B,ZNF546,ZNF624,ZNF594","ZFP62","ZNF814[36,38],ZNF629[33,34],ZNF347[34,36],ZNF836[39,38],ZNF473[33,34],ZNF268[43,41],ZNF845[40,37],ZNF585A[34,42],ZNF160[37,41],ZNF658[41,35],ZNF197[38,33],ZNF841[40,39],ZNF616[37,43],ZNF585B[34,40],ZNF808[39,39],ZNF107[43,49],ZNF99[43,45],ZNF43[43,48],ZNF721[43,42],ZNF493[36,42],ZNF780B[39,42],ZNF546[39,42],ZNF624[39,40],ZNF594[37,42]","snRNA","snRNA",16914750,".",".",".",".",".",".","GO:0006398,GO:0031124,GO:0008334","histone mRNA 3'-end processing,mRNA 3'-end processing,histone mRNA metabolic process","GO:0005515,GO:0003676,GO:0046872,GO:0003677,GO:0005622,GO:0005654,GO:0015030,GO:0006366,GO:0006355,GO:0010467,GO:0006398,GO:0031124,GO:0006369,GO:0008334","protein binding,nucleic acid binding,metal ion binding,DNA binding,intracellular,nucleoplasm,Cajal body,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,gene expression,histone mRNA 3'-end processing,mRNA 3'-end processing,termination of RNA polymerase II transcription,histone mRNA metabolic process","."]
["FCF1","FCF1 small subunit (SSU) processome component homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:20220]","ENSG00000119616","ENSP00000450750",1,"Fcf1[1]","family-719","FCF1",".",".","rRNA","rRNA","FCF1 yeast homolog",".","RNArelated",".",1,".",".","GO:0006364","rRNA processing","GO:0032040,GO:0005730,GO:0006364","small-subunit processome,nucleolus,rRNA processing","."]
["URB1","URB1 ribosome biogenesis 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17344]","ENSG00000142207","ENSP00000372199",1,"Npa1[1]","family-72","URB1",".",".","rRNA","putative rRNA","by homology","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005488,GO:0005730","binding,nucleolus","."]
["CARS","cysteinyl-tRNA synthetase [Source:HGNC Symbol;Acc:1493]","ENSG00000110619","ENSP00000278224",1,"tRNA-synt_1e[1]","family-720","CARS,CARS2","CARS","CARS2[24,35]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004817,GO:0004812,GO:0006423,GO:0006418,GO:0000049","cysteine-tRNA ligase activity,aminoacyl-tRNA ligase activity,cysteinyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA binding","GO:0000166,GO:0005524,GO:0004817,GO:0004812,GO:0005737,GO:0006423,GO:0006418,GO:0005515,GO:0042803,GO:0046872,GO:0000049,GO:0005829,GO:0010467","nucleotide binding,ATP binding,cysteine-tRNA ligase activity,aminoacyl-tRNA ligase activity,cytoplasm,cysteinyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,protein binding,protein homodimerization activity,metal ion binding,tRNA binding,cytosol,gene expression","."]
["CARS2","cysteinyl-tRNA synthetase 2, mitochondrial (putative) [Source:HGNC Symbol;Acc:25695]","ENSG00000134905","ENSP00000257347",1,"tRNA-synt_1e[1]","family-720","CARS,CARS2","CARS","CARS2[24,35]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0006418,GO:0004824,GO:0006430,GO:0004817,GO:0006423","aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,lysine-tRNA ligase activity,lysyl-tRNA aminoacylation,cysteine-tRNA ligase activity,cysteinyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0006418,GO:0004824,GO:0005737,GO:0006430,GO:0046872,GO:0004817,GO:0005829,GO:0005759,GO:0010467,GO:0006423","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,tRNA aminoacylation for protein translation,lysine-tRNA ligase activity,cytoplasm,lysyl-tRNA aminoacylation,metal ion binding,cysteine-tRNA ligase activity,cytosol,mitochondrial matrix,gene expression,cysteinyl-tRNA aminoacylation","."]
["CELF1","CUGBP, Elav-like family member 1 [Source:HGNC Symbol;Acc:2549]","ENSG00000149187","ENSP00000351409",3,"RRM_1[3]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0031369,GO:0000900,GO:0030529,GO:0006397,GO:0043484,GO:0006376,GO:0016246","RNA binding,mRNA binding,translation initiation factor binding,translation repressor activity, nucleic acid binding,ribonucleoprotein complex,mRNA processing,regulation of RNA splicing,mRNA splice site selection,RNA interference","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003729,GO:0031369,GO:0000900,GO:0042835,GO:0005634,GO:0005737,GO:0030529,GO:0009790,GO:0006397,GO:0043484,GO:0007286,GO:0006376,GO:0007281,GO:0040018,GO:0016246","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA binding,translation initiation factor binding,translation repressor activity, nucleic acid binding,BRE binding,nucleus,cytoplasm,ribonucleoprotein complex,embryo development,mRNA processing,regulation of RNA splicing,spermatid development,mRNA splice site selection,germ cell development,positive regulation of multicellular organism growth,RNA interference","."]
["CELF2","CUGBP, Elav-like family member 2 [Source:HGNC Symbol;Acc:2550]","ENSG00000048740","ENSP00000388530",3,"RRM_1[3]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0006376,GO:0006397,GO:0006396","RNA binding,mRNA splice site selection,mRNA processing,RNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005737,GO:0006376,GO:0006397,GO:0006396,GO:0008016","nucleotide binding,RNA binding,nucleic acid binding,nucleus,cytoplasm,mRNA splice site selection,mRNA processing,RNA processing,regulation of heart contraction","."]
["CELF3","CUGBP, Elav-like family member 3 [Source:HGNC Symbol;Acc:11967]","ENSG00000159409","ENSP00000290585",3,"RRM_1[3]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0003729,GO:0008380,GO:0000381,GO:0000398,GO:0048026","RNA binding,mRNA binding,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,positive regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0003723,GO:0003729,GO:0005737,GO:0005634,GO:0007283,GO:0008380,GO:0000381,GO:0000398,GO:0030317,GO:0048026","nucleotide binding,nucleic acid binding,RNA binding,mRNA binding,cytoplasm,nucleus,spermatogenesis,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,sperm motility,positive regulation of mRNA splicing, via spliceosome","."]
["CELF4","CUGBP, Elav-like family member 4 [Source:HGNC Symbol;Acc:14015]","ENSG00000101489","ENSP00000335631",3,"RRM_5[1],RRM_1[2]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003729,GO:0000900,GO:0000381,GO:0006376,GO:0000380,GO:0048026","mRNA binding,translation repressor activity, nucleic acid binding,regulation of alternative mRNA splicing, via spliceosome,mRNA splice site selection,alternative mRNA splicing, via spliceosome,positive regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0003729,GO:0000900,GO:0042835,GO:0005634,GO:0005737,GO:0009790,GO:0000381,GO:0006376,GO:0007281,GO:0000380,GO:0090394,GO:0048026","nucleotide binding,nucleic acid binding,mRNA binding,translation repressor activity, nucleic acid binding,BRE binding,nucleus,cytoplasm,embryo development,regulation of alternative mRNA splicing, via spliceosome,mRNA splice site selection,germ cell development,alternative mRNA splicing, via spliceosome,negative regulation of excitatory postsynaptic membrane potential,positive regulation of mRNA splicing, via spliceosome","."]
["CELF5","CUGBP, Elav-like family member 5 [Source:HGNC Symbol;Acc:14058]","ENSG00000161082","ENSP00000292672",3,"RRM_1[3]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0006397","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,mRNA processing","."]
["CELF6","CUGBP, Elav-like family member 6 [Source:HGNC Symbol;Acc:14059]","ENSG00000140488","ENSP00000457863",3,"RRM_1[3]","family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","CELF1","CELF2[77,76],CELF4[42,45],CELF5[42,44],CELF6[41,44],CELF3[42,46],CELF6[41,44]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003723,GO:0006397,GO:0000381","RNA binding,mRNA processing,regulation of alternative mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005737,GO:0006397,GO:0000381","nucleotide binding,nucleic acid binding,RNA binding,nucleus,cytoplasm,mRNA processing,regulation of alternative mRNA splicing, via spliceosome","."]
["XPO1","exportin 1 (CRM1 homolog, yeast) [Source:HGNC Symbol;Acc:12825]","ENSG00000082898","ENSP00000385559",3,"IBN_N[1],Xpo1[1],CRM1_C[1]","family-722","XPO1",".",".","mRNA","mRNA/snRNA","CRM1",".",".",".",".",1,".","GO:0003723,GO:0030529,GO:0016070,GO:0016071,GO:0051028","RNA binding,ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,mRNA transport","GO:0005488,GO:0019904,GO:0008565,GO:0005634,GO:0000122,GO:0006611,GO:0042493,GO:0034504,GO:0042176,GO:0010824,GO:0046825,GO:0008536,GO:0006886,GO:0003723,GO:0005515,GO:0005215,GO:0005737,GO:0005829,GO:0005730,GO:0005654,GO:0030529,GO:0005635,GO:0000776,GO:0015030,GO:0005642,GO:0000278,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0051028,GO:0007179,GO:0030512,GO:0019048,GO:0019058,GO:0075733","binding,protein domain specific binding,protein transporter activity,nucleus,negative regulation of transcription from RNA polymerase II promoter,protein export from nucleus,response to drug,protein localization to nucleus,regulation of protein catabolic process,regulation of centrosome duplication,regulation of protein export from nucleus,Ran GTPase binding,intracellular protein transport,RNA binding,protein binding,transporter activity,cytoplasm,cytosol,nucleolus,nucleoplasm,ribonucleoprotein complex,nuclear envelope,kinetochore,Cajal body,annulate lamellae,mitotic cell cycle,viral process,gene expression,RNA metabolic process,mRNA metabolic process,mRNA transport,transforming growth factor beta receptor signaling pathway,negative regulation of transforming growth factor beta receptor signaling pathway,modulation by virus of host morphology or physiology,viral life cycle,intracellular transport of virus","."]
["DDX17","DEAD (Asp-Glu-Ala-Asp) box helicase 17 [Source:HGNC Symbol;Acc:2740]","ENSG00000100201","ENSP00000380033",2,"Helicase_C[1],DEAD[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","mRNA","mRNA",12138182,"helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003724,GO:0008186,GO:0006396","RNA binding,RNA helicase activity,RNA-dependent ATPase activity,RNA processing","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003723,GO:0005515,GO:0030331,GO:0003713,GO:0003724,GO:0008186,GO:0005634,GO:0005730,GO:0006351,GO:0045944,GO:0006396,GO:0033148,GO:2001014,GO:0009791,GO:0072358","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA binding,protein binding,estrogen receptor binding,transcription coactivator activity,RNA helicase activity,RNA-dependent ATPase activity,nucleus,nucleolus,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,RNA processing,positive regulation of intracellular estrogen receptor signaling pathway,regulation of skeletal muscle cell differentiation,post-embryonic development,cardiovascular system development","."]
["DDX46","DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Source:HGNC Symbol;Acc:18681]","ENSG00000145833","ENSP00000416534",2,"Helicase_C[1],DEAD[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","snRNA","snRNA","14713954, The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. [provided by RefSeq, Jul 2008]","helicase",".",".",1,1,".","GO:0003723,GO:0006397,GO:0008380","RNA binding,mRNA processing,RNA splicing","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634,GO:0005730,GO:0016607,GO:0015030,GO:0006397,GO:0008380","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus,nucleolus,nuclear speck,Cajal body,mRNA processing,RNA splicing","."]
["DDX5","DEAD (Asp-Glu-Ala-Asp) box helicase 5 [Source:HGNC Symbol;Acc:2746]","ENSG00000263077","ENSP00000459637",4,"P68HR[2],Helicase_C[1],DEAD[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","mRNA","mRNA","RBP in alternative splicing","helicase","experimentally validated",1,1,1,".","GO:0004004,GO:0003724,GO:0036002,GO:0030529,GO:0071013,GO:0000381,GO:0000398","ATP-dependent RNA helicase activity,RNA helicase activity,pre-mRNA binding,ribonucleoprotein complex,catalytic step 2 spliceosome,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome","GO:0019899,GO:0048306,GO:0005516,GO:0003712,GO:0004004,GO:0045893,GO:0001701,GO:0007623,GO:0045069,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003724,GO:0016818,GO:0005634,GO:0005515,GO:0030331,GO:0003713,GO:0050681,GO:0036002,GO:0005730,GO:0030529,GO:0071013,GO:0000122,GO:0006351,GO:0045944,GO:0000381,GO:0000398,GO:0016049,GO:0043517,GO:0045667,GO:0033148,GO:0072332,GO:2001014,GO:0060765","enzyme binding,calcium-dependent protein binding,calmodulin binding,transcription cofactor activity,ATP-dependent RNA helicase activity,positive regulation of transcription, DNA-dependent,in utero embryonic development,circadian rhythm,regulation of viral genome replication,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA helicase activity,hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides,nucleus,protein binding,estrogen receptor binding,transcription coactivator activity,androgen receptor binding,pre-mRNA binding,nucleolus,ribonucleoprotein complex,catalytic step 2 spliceosome,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,cell growth,positive regulation of DNA damage response, signal transduction by p53 class mediator,regulation of osteoblast differentiation,positive regulation of intracellular estrogen receptor signaling pathway,intrinsic apoptotic signaling pathway by p53 class mediator,regulation of skeletal muscle cell differentiation,regulation of androgen receptor signaling pathway","."]
["DDX42","DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 [Source:HGNC Symbol;Acc:18676]","ENSG00000198231","ENSP00000352308",2,"Helicase_C[1],DEAD[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","mRNA","mRNA","by homology , 16397294 ","helicase",".",".",1,1,".","GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634,GO:0005737,GO:0016607,GO:0015030,GO:0008104","RNA binding,protein binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus,cytoplasm,nuclear speck,Cajal body,protein localization","."]
["DDX43","DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Source:HGNC Symbol;Acc:18677]","ENSG00000080007","ENSP00000359361",3,"Helicase_C[1],DEAD[1],KH_1[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","mRNA","mRNA","yeast homolog DBP2",".",".",".",".",".",1,"GO:0003723,GO:0004004","RNA binding,ATP-dependent RNA helicase activity","GO:0003723,GO:0004386,GO:0005524,GO:0003676,GO:0008026,GO:0004004,GO:0005622","RNA binding,helicase activity,ATP binding,nucleic acid binding,ATP-dependent helicase activity,ATP-dependent RNA helicase activity,intracellular","."]
["DDX53","DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 [Source:HGNC Symbol;Acc:20083]","ENSG00000184735","ENSP00000368667",3,"Helicase_C[1],DEAD[1],KH_1[1]","family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","DDX17","DDX5[57,68],DDX42[30,23],DDX46[31,22],DDX53[27,31],DDX43[27,31]","mRNA","mRNA","yeast homolog DBP2",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0005634","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,nucleus","."]
["FIP1L1","FIP1 like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:19124]","ENSG00000145216","ENSP00000423325",2,"Fip1[1],Pkinase_Tyr[1]","family-724","FIP1L1",".",".","mRNA","mRNA","This gene encodes a subunit of the CPSF (cleavage and polyadenylation specificity factor) complex that polyadenylates the 3' end of mRNA precursors. This gene, the homolog of yeast Fip1 (factor interacting with PAP), binds to U-rich sequences of pre-mRNA and stimulates poly(A) polymerase activity.","RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0005847,GO:0006397","RNA binding,mRNA cleavage and polyadenylation specificity factor complex,mRNA processing","GO:0003723,GO:0005524,GO:0004672,GO:0004713,GO:0004714,GO:0016772,GO:0016021,GO:0005634,GO:0005847,GO:0006397,GO:0006468,GO:0007169,GO:0005515","RNA binding,ATP binding,protein kinase activity,protein tyrosine kinase activity,transmembrane receptor protein tyrosine kinase activity,transferase activity, transferring phosphorus-containing groups,integral to membrane,nucleus,mRNA cleavage and polyadenylation specificity factor complex,mRNA processing,protein phosphorylation,transmembrane receptor protein tyrosine kinase signaling pathway,protein binding"," HYPEREOSINOPHILIC SYNDROME, IDIOPATHIC; HES"]
["MRPL14","mitochondrial ribosomal protein L14 [Source:HGNC Symbol;Acc:14279]","ENSG00000180992","ENSP00000361084",1,"Ribosomal_L14[1]","family-725","MRPL14",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005739,GO:0005840,GO:0006412","structural constituent of ribosome,mitochondrion,ribosome,translation","."]
["TXNL4A","thioredoxin-like 4A [Source:HGNC Symbol;Acc:30551]","ENSG00000141759","ENSP00000269601",1,"DIM1[1]","family-726","TXNL4A,TXNL4B","TXNL4A","TXNL4B[35,34]","snRNA","putative snRNA/mRNA","23519793, TXNL4A (thioredoxin-like 4A) is an essential protein conserved from yeast to humans and is a component of the pre-mRNA splicing machinery. TXNL4B was identified as a TXNL4-family protein that also interacts with Prp6, an integral component of the U4/U6ÃƒÆ’Ã¢â‚¬Å¡Ãƒâ€šÃ‚Â·U5 tri-snRNP complex, and has been shown to function in pre-mRNA splicing. A",".",".",".",".",".",".","GO:0005681,GO:0008380,GO:0000398,GO:0000245,GO:0000375","spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,RNA splicing, via transesterification reactions","GO:0005681,GO:0007067,GO:0045454,GO:0005634,GO:0005737,GO:0005515,GO:0005654,GO:0010467,GO:0008380,GO:0000398,GO:0000245,GO:0000375","spliceosomal complex,mitosis,cell redox homeostasis,nucleus,cytoplasm,protein binding,nucleoplasm,gene expression,RNA splicing,mRNA splicing, via spliceosome,spliceosomal complex assembly,RNA splicing, via transesterification reactions","."]
["TXNL4B","thioredoxin-like 4B [Source:HGNC Symbol;Acc:26041]","ENSG00000140830","ENSP00000268483",1,"DIM1[1]","family-726","TXNL4A,TXNL4B","TXNL4A","TXNL4B[35,34]","snRNA","putative snRNA/mRNA","23519793, TXNL4A (thioredoxin-like 4A) is an essential protein conserved from yeast to humans and is a component of the pre-mRNA splicing machinery. TXNL4B was identified as a TXNL4-family protein that also interacts with Prp6, an integral component of the U4/U6ÃƒÆ’Ã¢â‚¬Å¡Ãƒâ€šÃ‚Â·U5 tri-snRNP complex, and has been shown to function in pre-mRNA splicing. A",".",".",".",".",".",".","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0005681,GO:0007067,GO:0006397,GO:0008380,GO:0045454","spliceosomal complex,mitosis,mRNA processing,RNA splicing,cell redox homeostasis","."]
["RBM39","RNA binding motif protein 39 [Source:HGNC Symbol;Acc:15923]","ENSG00000131051","ENSP00000436747",4,"RRM_5[1],RRM_1[2],RBM39linker[1]","family-727","RBM23,RBM39","RBM23","RBM39[61,50]","mRNA","mRNA","by homology, This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0006396","RNA binding,mRNA processing,RNA splicing,RNA processing","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005813,GO:0015630,GO:0006397,GO:0005515,GO:0005654,GO:0016607,GO:0006351,GO:0006355,GO:0008380,GO:0006396","nucleotide binding,RNA binding,nucleic acid binding,nucleus,centrosome,microtubule cytoskeleton,mRNA processing,protein binding,nucleoplasm,nuclear speck,transcription, DNA-templated,regulation of transcription, DNA-dependent,RNA splicing,RNA processing","."]
["RBM23","RNA binding motif protein 23 [Source:HGNC Symbol;Acc:20155]","ENSG00000100461","ENSP00000339220",3,"RRM_1[2],RBM39linker[1]","family-727","RBM23,RBM39","RBM23","RBM39[61,50]","mRNA","putative mRNA","This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",1,"GO:0003723,GO:0006397","RNA binding,mRNA processing","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0006397,GO:0005515","nucleotide binding,nucleic acid binding,RNA binding,nucleus,mRNA processing,protein binding","."]
["CPEB1","cytoplasmic polyadenylation element binding protein 1 [Source:HGNC Symbol;Acc:21744]","ENSG00000214575","ENSP00000458081",2,"RRM_1[1],RRM_6[1]","family-728","CPEB1,CPEB2,CPEB4,CPEB3","CPEB1","CPEB2[29,15],CPEB4[28,22],CPEB3[28,22]","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0003729,GO:0006417,GO:0035925,GO:0000900,GO:0000932,GO:0006397","mRNA binding,regulation of translation,mRNA 3'-UTR AU-rich region binding,translation repressor activity, nucleic acid binding,cytoplasmic mRNA processing body,mRNA processing","GO:0000166,GO:0003676,GO:0003729,GO:0016020,GO:0072687,GO:0007130,GO:0006417,GO:0048168,GO:0046872,GO:0035925,GO:0000900,GO:0005634,GO:0005737,GO:0000932,GO:0030054,GO:0045211,GO:0030425,GO:0014069,GO:0006397,GO:0032869,GO:0071456,GO:0071230,GO:2000766","nucleotide binding,nucleic acid binding,mRNA binding,membrane,meiotic spindle,synaptonemal complex assembly,regulation of translation,regulation of neuronal synaptic plasticity,metal ion binding,mRNA 3'-UTR AU-rich region binding,translation repressor activity, nucleic acid binding,nucleus,cytoplasm,cytoplasmic mRNA processing body,cell junction,postsynaptic membrane,dendrite,postsynaptic density,mRNA processing,cellular response to insulin stimulus,cellular response to hypoxia,cellular response to amino acid stimulus,negative regulation of cytoplasmic translation","."]
["CPEB2","cytoplasmic polyadenylation element binding protein 2 [Source:HGNC Symbol;Acc:21745]","ENSG00000137449","ENSP00000371838",1,"RRM_1[1]","family-728","CPEB1,CPEB2,CPEB4,CPEB3","CPEB1","CPEB2[29,15],CPEB4[28,22],CPEB3[28,22]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0008187,GO:0043022,GO:0035925,GO:0043024,GO:0043023,GO:0000900","poly-pyrimidine tract binding,ribosome binding,mRNA 3'-UTR AU-rich region binding,ribosomal small subunit binding,ribosomal large subunit binding,translation repressor activity, nucleic acid binding","GO:0000166,GO:0003676,GO:0008187,GO:0005737,GO:0005844,GO:0045900,GO:0033125,GO:0043022,GO:0005095,GO:0035925,GO:0043024,GO:0043023,GO:0000900,GO:0005634,GO:1990124,GO:0032869,GO:0071456,GO:0034599,GO:0034260,GO:0071243,GO:1900248,GO:2000766,GO:0005515","nucleotide binding,nucleic acid binding,poly-pyrimidine tract binding,cytoplasm,polysome,negative regulation of translational elongation,negative regulation of GTP catabolic process,ribosome binding,GTPase inhibitor activity,mRNA 3'-UTR AU-rich region binding,ribosomal small subunit binding,ribosomal large subunit binding,translation repressor activity, nucleic acid binding,nucleus,messenger ribonucleoprotein complex,cellular response to insulin stimulus,cellular response to hypoxia,cellular response to oxidative stress,negative regulation of GTPase activity,cellular response to arsenic-containing substance,negative regulation of cytoplasmic translational elongation,negative regulation of cytoplasmic translation,protein binding","."]
["CPEB3","cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:21746]","ENSG00000107864","ENSP00000398310",1,"RRM_1[1]","family-728","CPEB1,CPEB2,CPEB4,CPEB3","CPEB1","CPEB2[29,15],CPEB4[28,22],CPEB3[28,22]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0003730,GO:0035925,GO:0008135,GO:0035613,GO:0000900,GO:0060213,GO:1900153,GO:0045727","RNA binding,mRNA 3'-UTR binding,mRNA 3'-UTR AU-rich region binding,translation factor activity, nucleic acid binding,RNA stem-loop binding,translation repressor activity, nucleic acid binding,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,positive regulation of translation","GO:0005515,GO:0003723,GO:0000166,GO:0003676,GO:0003730,GO:0035925,GO:0008135,GO:0035613,GO:0000900,GO:0045202,GO:0005634,GO:0005737,GO:0030014,GO:0030425,GO:0043005,GO:0097440,GO:0017148,GO:0000122,GO:0060213,GO:1900153,GO:0045727,GO:0060999,GO:0007616,GO:0048167,GO:0071230,GO:0060998,GO:1900248,GO:0061158,GO:1900365","protein binding,RNA binding,nucleotide binding,nucleic acid binding,mRNA 3'-UTR binding,mRNA 3'-UTR AU-rich region binding,translation factor activity, nucleic acid binding,RNA stem-loop binding,translation repressor activity, nucleic acid binding,synapse,nucleus,cytoplasm,CCR4-NOT complex,dendrite,neuron projection,apical dendrite,negative regulation of translation,negative regulation of transcription from RNA polymerase II promoter,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,positive regulation of translation,positive regulation of dendritic spine development,long-term memory,regulation of synaptic plasticity,cellular response to amino acid stimulus,regulation of dendritic spine development,negative regulation of cytoplasmic translational elongation,3'-UTR-mediated mRNA destabilization,positive regulation of mRNA polyadenylation","."]
["CPEB4","cytoplasmic polyadenylation element binding protein 4 [Source:HGNC Symbol;Acc:21747]","ENSG00000113742","ENSP00000429048",1,"RRM_1[1]","family-728","CPEB1,CPEB2,CPEB4,CPEB3","CPEB1","CPEB2[29,15],CPEB4[28,22],CPEB3[28,22]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005737,GO:0005783,GO:0030425,GO:0014069,GO:0043524,GO:0042149,GO:0002931,GO:0071230,GO:0035235,GO:0036294,GO:0045202","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,cytoplasm,endoplasmic reticulum,dendrite,postsynaptic density,negative regulation of neuron apoptotic process,cellular response to glucose starvation,response to ischemia,cellular response to amino acid stimulus,ionotropic glutamate receptor signaling pathway,cellular response to decreased oxygen levels,synapse","."]
["INTS9","integrator complex subunit 9 [Source:HGNC Symbol;Acc:25592]","ENSG00000104299","ENSP00000429065",1,"Beta-Casp[1]","family-729","INTS9",".",".","snRNA","snRNA","22252320, This protein complex binds the C-terminal domain of RNA polymerase II and likely plays a role in small nuclear RNA processing",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0032039,GO:0016180,GO:0016787,GO:0005515","integrator complex,snRNA processing,hydrolase activity,protein binding","."]
["CACTIN","cactin, spliceosome C complex subunit [Source:HGNC Symbol;Acc:29938]","ENSG00000105298","ENSP00000415078",2,"CactinC_cactus[1],Cactin_mid[1]","family-73","CACTIN",".",".","mRNA","putative mRNA","established RBP ","candidate mRNA binder",".",".",1,".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0005634,GO:0071013,GO:0045087,GO:0007275,GO:0001933,GO:0032088,GO:0000398,GO:0071222,GO:0071347,GO:0071356,GO:0032720,GO:0031665,GO:0034122,GO:0060339,GO:0032688,GO:0032717","protein binding,nucleus,catalytic step 2 spliceosome,innate immune response,multicellular organismal development,negative regulation of protein phosphorylation,negative regulation of NF-kappaB transcription factor activity,mRNA splicing, via spliceosome,cellular response to lipopolysaccharide,cellular response to interleukin-1,cellular response to tumor necrosis factor,negative regulation of tumor necrosis factor production,negative regulation of lipopolysaccharide-mediated signaling pathway,negative regulation of toll-like receptor signaling pathway,negative regulation of type I interferon-mediated signaling pathway,negative regulation of interferon-beta production,negative regulation of interleukin-8 production","."]
["MPHOSPH6","M-phase phosphoprotein 6 [Source:HGNC Symbol;Acc:7214]","ENSG00000135698","ENSP00000456626",1,"MPP6[1]","family-730","MPHOSPH6",".",".","rRNA","rRNA",16396833,".",".",".",".",".",".","GO:0003723,GO:0000178,GO:0000176,GO:0000460","RNA binding,exosome (RNase complex),nuclear exosome (RNase complex),maturation of 5.8S rRNA","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005730,GO:0000178,GO:0000176,GO:0000460,GO:0000087","RNA binding,protein binding,nucleus,cytoplasm,nucleolus,exosome (RNase complex),nuclear exosome (RNase complex),maturation of 5.8S rRNA,mitotic M phase","."]
["RPL34","ribosomal protein L34 [Source:HGNC Symbol;Acc:10340]","ENSG00000109475","ENSP00000378160",1,"Ribosomal_L34e[1]","family-731","RPL34",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["OBFC1","oligonucleotide/oligosaccharide-binding fold containing 1 [Source:HGNC Symbol;Acc:26200]","ENSG00000107960","ENSP00000358779",2,"STN1_2[1],tRNA_anti-codon[1]","family-732","OBFC1",".",".","unknown","unknown","by domain, OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]",".",".",".",".",".",".",".",".","GO:0005515,GO:0003676,GO:0003697,GO:0043047,GO:0005634,GO:0043231,GO:0005730,GO:0000784,GO:0045111,GO:0070188,GO:0000723,GO:0045740,GO:0010833","protein binding,nucleic acid binding,single-stranded DNA binding,single-stranded telomeric DNA binding,nucleus,intracellular membrane-bounded organelle,nucleolus,nuclear chromosome, telomeric region,intermediate filament cytoskeleton,Stn1-Ten1 complex,telomere maintenance,positive regulation of DNA replication,telomere maintenance via telomere lengthening","."]
["RPS12","ribosomal protein S12 [Source:HGNC Symbol;Acc:10385]","ENSG00000112306","ENSP00000230050",1,"Ribosomal_L7Ae[1]","family-733","RPS12",".",".","ribosome","ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0022627,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,cytosolic small ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005829,GO:0022627,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytosol,cytosolic small ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["PRPF8","PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17340]","ENSG00000174231","ENSP00000460348",8,"PROCN[1],RRM_4[1],U6-snRNA_bdg[1],PROCT[1],PRO8NT[1],PRP8_domainIV[1],U5_2-snRNA_bdg[1],JAB[1]","family-734","PRPF8",".",".","snRNA","snRNA/mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",".","GO:0003723,GO:0005681,GO:0000398,GO:0017070,GO:0030623,GO:0071013,GO:0005682,GO:0006397,GO:0008380,GO:0000375","RNA binding,spliceosomal complex,mRNA splicing, via spliceosome,U6 snRNA binding,U5 snRNA binding,catalytic step 2 spliceosome,U5 snRNP,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions","GO:0003723,GO:0046982,GO:0005681,GO:0000398,GO:0017070,GO:0030623,GO:0005515,GO:0005654,GO:0016607,GO:0071013,GO:0005682,GO:0010467,GO:0006397,GO:0008380,GO:0000375","RNA binding,protein heterodimerization activity,spliceosomal complex,mRNA splicing, via spliceosome,U6 snRNA binding,U5 snRNA binding,protein binding,nucleoplasm,nuclear speck,catalytic step 2 spliceosome,U5 snRNP,gene expression,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions"," RETINITIS PIGMENTOSA 13; RP13"]
["SECISBP2L","SECIS binding protein 2-like [Source:HGNC Symbol;Acc:28997]","ENSG00000138593","ENSP00000370314",1,"Ribosomal_L7Ae[1]","family-735","SECISBP2,SECISBP2L","SECISBP2","SECISBP2L[30,23]","mRNA","mRNA","22530054, 22530054","RNAbinding","novel",1,1,".",".",".",".",".",".","."]
["SECISBP2","SECIS binding protein 2 [Source:HGNC Symbol;Acc:30972]","ENSG00000187742","ENSP00000364959",1,"Ribosomal_L7Ae[1]","family-735","SECISBP2,SECISBP2L","SECISBP2","SECISBP2L[30,23]","mRNA","mRNA","The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]",".","RNAbinding",".",1,".",".","GO:0003730,GO:0006412,GO:0043021,GO:0030529","mRNA 3'-UTR binding,translation,ribonucleoprotein complex binding,ribonucleoprotein complex","GO:0005739,GO:0003730,GO:0005634,GO:0006412,GO:0005515,GO:0043021,GO:0035368,GO:0030529","mitochondrion,mRNA 3'-UTR binding,nucleus,translation,protein binding,ribonucleoprotein complex binding,selenocysteine insertion sequence binding,ribonucleoprotein complex"," THYROID HORMONE METABOLISM, ABNORMAL"]
["RPUSD3","RNA pseudouridylate synthase domain containing 3 [Source:HGNC Symbol;Acc:28437]","ENSG00000156990","ENSP00000405054",1,"PseudoU_synth_2[1]","family-736","RPUSD3,RPUSD4","RPUSD3","RPUSD4[25,24]","mRNA","putative mRNA/tRNA/rRNA","by domain, 22658674, 22681889","RNAmod","RNAbinding",1,1,".",".","GO:0003723,GO:0009451","RNA binding,RNA modification","GO:0003723,GO:0009982,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification","."]
["RPUSD4","RNA pseudouridylate synthase domain containing 4 [Source:HGNC Symbol;Acc:25898]","ENSG00000165526","ENSP00000298317",1,"PseudoU_synth_2[1]","family-736","RPUSD3,RPUSD4","RPUSD3","RPUSD4[25,24]","mRNA","putative mRNA/tRNA/rRNA","by domain, 22658674, 22681889","RNAmod","RNAbinding",1,1,".",".","GO:0003723,GO:0009451","RNA binding,RNA modification","GO:0003723,GO:0009982,GO:0001522,GO:0009451,GO:0005515,GO:0005739","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification,protein binding,mitochondrion","."]
["DDX6","DEAD (Asp-Glu-Ala-Asp) box helicase 6 [Source:HGNC Symbol;Acc:2747]","ENSG00000269612","ENSP00000469200",2,"Helicase_C[1],DEAD[1]","family-737","DDX6",".",".","mRNA","mRNA","This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Mar 2012]","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003724,GO:0000932,GO:0010494,GO:0016070,GO:0016071,GO:0000288,GO:0033962,GO:0043928","RNA binding,RNA helicase activity,cytoplasmic mRNA processing body,cytoplasmic stress granule,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,cytoplasmic mRNA processing body assembly,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0003723,GO:0005515,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003724,GO:0005829,GO:0000932,GO:0010494,GO:0016442,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0033962,GO:0043928,GO:0005737","RNA binding,protein binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA helicase activity,cytosol,cytoplasmic mRNA processing body,cytoplasmic stress granule,RISC complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,cytoplasmic mRNA processing body assembly,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,cytoplasm","."]
["RPL28","ribosomal protein L28 [Source:HGNC Symbol;Acc:10330]","ENSG00000108107","ENSP00000453584",1,"Ribosomal_L28e[1]","family-738","RPL28",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,".",".","GO:0003723,GO:0003735,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0005840","RNA binding,structural constituent of ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosome","GO:0003723,GO:0005515,GO:0003735,GO:0005737,GO:0005829,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0005840","RNA binding,protein binding,structural constituent of ribosome,cytoplasm,cytosol,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosome","."]
["ELAC1","elaC homolog 1 (E. coli) [Source:HGNC Symbol;Acc:14197]","ENSG00000141642","ENSP00000464770",1,"Lactamase_B[1]","family-739","ELAC1",".",".","tRNA","putative tRNA",18573253,".",".",".",".",".",".","GO:0016891,GO:0042779","endoribonuclease activity, producing 5'-phosphomonoesters,tRNA 3'-trailer cleavage","GO:0016787,GO:0046872,GO:0016891,GO:0005634,GO:0005829,GO:0042779","hydrolase activity,metal ion binding,endoribonuclease activity, producing 5'-phosphomonoesters,nucleus,cytosol,tRNA 3'-trailer cleavage","."]
["NOM1","nucleolar protein with MIF4G domain 1 [Source:HGNC Symbol;Acc:13244]","ENSG00000146909","ENSP00000275820",2,"MIF4G[1],MA3[1]","family-74","NOM1",".",".","rRNA","putative rRNA","yeast homolog SGD1","RNAbinding",".",".",1,".",".","GO:0003723","RNA binding","GO:0005488,GO:0003723,GO:0005515,GO:0005730","binding,RNA binding,protein binding,nucleolus","."]
["TROVE2","TROVE domain family, member 2 [Source:HGNC Symbol;Acc:11313]","ENSG00000116747","ENSP00000472298",2,"DUF2201[1],TROVE[1]","family-740","TROVE2",".",".","ncRNA","Y RNA",23698747,".",".",".",".",".",1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0003723,GO:0005634,GO:0005737,GO:0030529,GO:0060271,GO:0046872,GO:0006383","RNA binding,nucleus,cytoplasm,ribonucleoprotein complex,cilium morphogenesis,metal ion binding,transcription from RNA polymerase III promoter","."]
["EEF1E1","eukaryotic translation elongation factor 1 epsilon 1 [Source:HGNC Symbol;Acc:3212]","ENSG00000124802","ENSP00000369038",1,"GST_C_3[1]","family-741","EEF1E1",".",".","tRNA","putative tRNA","This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]",".",".",".",".",".",".","GO:0006418","tRNA aminoacylation for protein translation","GO:0005634,GO:0005737,GO:0005515,GO:0005829,GO:0008285,GO:0010467,GO:0043065,GO:0006418,GO:0043517","nucleus,cytoplasm,protein binding,cytosol,negative regulation of cell proliferation,gene expression,positive regulation of apoptotic process,tRNA aminoacylation for protein translation,positive regulation of DNA damage response, signal transduction by p53 class mediator","."]
["TARSL2","threonyl-tRNA synthetase-like 2 [Source:HGNC Symbol;Acc:24728]","ENSG00000185418","ENSP00000338093",4,"tRNA-synt_2b[1],TGS[1],HGTP_anticodon[1],tRNA_SAD[1]","family-742","TARS,TARS2,TARSL2","TARS","TARS2[49,52],TARSL2[68,64]","tRNA","putative tRNA","by domain",".",".",".",".",".",".","GO:0004829,GO:0004812,GO:0016876,GO:0006435,GO:0006418,GO:0043039","threonine-tRNA ligase activity,aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004829,GO:0004812,GO:0016876,GO:0005737,GO:0006435,GO:0006418,GO:0043039","nucleotide binding,ATP binding,threonine-tRNA ligase activity,aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,cytoplasm,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation","."]
["TARS","threonyl-tRNA synthetase [Source:HGNC Symbol;Acc:11572]","ENSG00000113407","ENSP00000387710",5,"tRNA-synt_2b[1],TGS[2],HGTP_anticodon[1],tRNA_SAD[1]","family-742","TARS,TARS2,TARSL2","TARS","TARS2[49,52],TARSL2[68,64]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004829,GO:0004812,GO:0016876,GO:0006435,GO:0006418,GO:0043039,GO:0006412","threonine-tRNA ligase activity,aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation,translation","GO:0000166,GO:0005524,GO:0004829,GO:0004812,GO:0016876,GO:0005737,GO:0006435,GO:0006418,GO:0043039,GO:0015629,GO:0042803,GO:0005829,GO:0006412,GO:0010467","nucleotide binding,ATP binding,threonine-tRNA ligase activity,aminoacyl-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,cytoplasm,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation,actin cytoskeleton,protein homodimerization activity,cytosol,translation,gene expression","."]
["TARS2","threonyl-tRNA synthetase 2, mitochondrial (putative) [Source:HGNC Symbol;Acc:30740]","ENSG00000143374","ENSP00000358060",4,"tRNA-synt_2b[1],TGS[1],HGTP_anticodon[1],tRNA_SAD[1]","family-742","TARS,TARS2,TARSL2","TARS","TARS2[49,52],TARSL2[68,64]","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004829,GO:0016876,GO:0006435,GO:0006418,GO:0043039,GO:0070159","aminoacyl-tRNA ligase activity,threonine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation,mitochondrial threonyl-tRNA aminoacylation","GO:0004812,GO:0000166,GO:0005524,GO:0004829,GO:0016876,GO:0005737,GO:0006435,GO:0006418,GO:0043039,GO:0005739,GO:0005759,GO:0010467,GO:0070159","aminoacyl-tRNA ligase activity,nucleotide binding,ATP binding,threonine-tRNA ligase activity,ligase activity, forming aminoacyl-tRNA and related compounds,cytoplasm,threonyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA aminoacylation,mitochondrion,mitochondrial matrix,gene expression,mitochondrial threonyl-tRNA aminoacylation","."]
["IARS","isoleucyl-tRNA synthetase [Source:HGNC Symbol;Acc:5330]","ENSG00000196305","ENSP00000406448",2,"Anticodon_1[1],tRNA-synt_1[1]","family-743","IARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0002161,GO:0004812,GO:0004822,GO:0006418,GO:0006428","aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,isoleucine-tRNA ligase activity,tRNA aminoacylation for protein translation,isoleucyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0002161,GO:0004812,GO:0004822,GO:0005737,GO:0006418,GO:0006428,GO:0005515,GO:0005634,GO:0005829,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,isoleucine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,isoleucyl-tRNA aminoacylation,protein binding,nucleus,cytosol,gene expression","."]
["RPL18A","ribosomal protein L18a [Source:HGNC Symbol;Acc:10311]","ENSG00000105640","ENSP00000471584",1,"Ribosomal_L18ae[1]","family-744","RPL18A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ESF1","ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15898]","ENSG00000089048","ENSP00000202816",1,"NUC153[1]","family-745","ESF1",".",".","rRNA","putative rRNA","Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels ","RNAbinding","novel",1,1,1,".",".",".","GO:0005634,GO:0005730,GO:0005654,GO:0006351,GO:0006355","nucleus,nucleolus,nucleoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["EEF2","eukaryotic translation elongation factor 2 [Source:HGNC Symbol;Acc:3214]","ENSG00000167658","ENSP00000307940",5,"EFG_C[1],GTP_EFTU_D2[1],EFG_IV[1],EFG_II[1],GTP_EFTU[1]","family-746","EEF2,EFTUD2","EEF2","EFTUD2[39,34]","tRNA","tRNA/mRNA","established RBP ","RNAbinding","RNArelated",1,1,1,".","GO:0003746,GO:0030529,GO:0006414,GO:0006412","translation elongation factor activity,ribonucleoprotein complex,translational elongation,translation","GO:0005515,GO:0005525,GO:0003924,GO:0003746,GO:0005829,GO:0030529,GO:0005844,GO:0006184,GO:0006414,GO:0006412,GO:0010467,GO:0044267","protein binding,GTP binding,GTPase activity,translation elongation factor activity,cytosol,ribonucleoprotein complex,polysome,GTP catabolic process,translational elongation,translation,gene expression,cellular protein metabolic process","."]
["EFTUD2","elongation factor Tu GTP binding domain containing 2 [Source:HGNC Symbol;Acc:30858]","ENSG00000108883","ENSP00000465058",5,"EFG_C[1],GTP_EFTU_D2[1],EFG_IV[1],EFG_II[1],GTP_EFTU[1]","family-746","EEF2,EFTUD2","EEF2","EFTUD2[39,34]","tRNA","tRNA/mRNA","established RBP ","RNAbinding","RNArelated",1,1,".",".","GO:0005681,GO:0071013,GO:0006397,GO:0008380,GO:0000398","spliceosomal complex,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome","GO:0005634,GO:0005525,GO:0005515,GO:0003924,GO:0005737,GO:0005622,GO:0005654,GO:0005681,GO:0016607,GO:0015030,GO:0071013,GO:0007264,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006184","nucleus,GTP binding,protein binding,GTPase activity,cytoplasm,intracellular,nucleoplasm,spliceosomal complex,nuclear speck,Cajal body,catalytic step 2 spliceosome,small GTPase mediated signal transduction,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,GTP catabolic process"," MANDIBULOFACIAL DYSOSTOSIS, GUION-ALMEIDA TYPE; MFDGA"]
["DDX60","DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Source:HGNC Symbol;Acc:25942]","ENSG00000137628","ENSP00000377344",2,"Helicase_C[1],DEAD[1]","family-747","DDX60,DDX60L","DDX60","DDX60L[65,65]","ncRNA","ncRNA","21791617, MTR4 yeast homolog",".",".",".",".",".",".","GO:0003723,GO:0003725,GO:0003727","RNA binding,double-stranded RNA binding,single-stranded RNA binding","GO:0003723,GO:0005737,GO:0051607,GO:0005515,GO:0005524,GO:0003676,GO:0003677,GO:0003690,GO:0003725,GO:0003727,GO:0008026,GO:0016787,GO:0004386,GO:0045087,GO:0009615,GO:1900245,GO:1900246","RNA binding,cytoplasm,defense response to virus,protein binding,ATP binding,nucleic acid binding,DNA binding,double-stranded DNA binding,double-stranded RNA binding,single-stranded RNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,innate immune response,response to virus,positive regulation of MDA-5 signaling pathway,positive regulation of RIG-I signaling pathway","."]
["DDX60L","DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Source:HGNC Symbol;Acc:26429]","ENSG00000181381","ENSP00000422423",2,"Helicase_C[1],DEAD[1]","family-747","DDX60,DDX60L","DDX60","DDX60L[65,65]","ncRNA","putative ncRNA","by homology",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003677,GO:0016787","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,DNA binding,hydrolase activity","."]
["MRPL2","mitochondrial ribosomal protein L2 [Source:HGNC Symbol;Acc:14056]","ENSG00000112651","ENSP00000230413",2,"Ribosomal_L2_C[1],Ribosomal_L2[1]","family-748","MRPL2",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005840,GO:0006412,GO:0005622,GO:0005739","structural constituent of ribosome,ribosome,translation,intracellular,mitochondrion","."]
["SLC4A1AP","solute carrier family 4 (anion exchanger), member 1, adaptor protein [Source:HGNC Symbol;Acc:13813]","ENSG00000163798","ENSP00000323837",2,"FHA[1],dsrm[1]","family-749","SLC4A1AP",".",".","unknown","unknown","by domain",".",".",".",".",".",".",".",".","GO:0005515,GO:0005634,GO:0005737","protein binding,nucleus,cytoplasm","."]
["MAZ","MYC-associated zinc finger protein (purine-binding transcription factor) [Source:HGNC Symbol;Acc:6914]","ENSG00000103495","ENSP00000443956",3,"zf-C2H2_4[1],zf-H2C2_2[1],zf-C2H2[1]","family-75","MAZ,PATZ1,VEZF1","MAZ","PATZ1[34,24],VEZF1[32,30]","unknown","unknown","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0003723","RNA binding","GO:0046872,GO:0003677,GO:0003682,GO:0000981,GO:0005634,GO:0005737,GO:0045944,GO:0003676,GO:0003723,GO:0005515,GO:0000979,GO:0006366,GO:0006367,GO:0006369,GO:0005525","metal ion binding,DNA binding,chromatin binding,sequence-specific DNA binding RNA polymerase II transcription factor activity,nucleus,cytoplasm,positive regulation of transcription from RNA polymerase II promoter,nucleic acid binding,RNA binding,protein binding,RNA polymerase II core promoter sequence-specific DNA binding,transcription from RNA polymerase II promoter,transcription initiation from RNA polymerase II promoter,termination of RNA polymerase II transcription,GTP binding","."]
["EIF2S3L","Putative eukaryotic translation initiation factor 2 subunit 3-like protein  [Source:UniProtKB/Swiss-Prot;Acc:Q2VIR3]","ENSG00000180574","ENSP00000445077",3,"GTP_EFTU_D2[1],eIF2_C[1],GTP_EFTU[1]","family-750","EIF2S3,EIF2S3L","EIF2S3","EIF2S3L[92,93]","tRNA","tRNA","by homology",".",".",".",".",".",".","GO:0003743","translation initiation factor activity","GO:0005525,GO:0003924,GO:0003743","GTP binding,GTPase activity,translation initiation factor activity","."]
["EIF2S3","eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa [Source:HGNC Symbol;Acc:3267]","ENSG00000130741","ENSP00000253039",3,"GTP_EFTU_D2[1],eIF2_C[1],GTP_EFTU[1]","family-750","EIF2S3,EIF2S3L","EIF2S3","EIF2S3L[92,93]","tRNA","tRNA","The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]",".",".",".",".",".",".","GO:0003743,GO:0008135,GO:0006412,GO:0006413","translation initiation factor activity,translation factor activity, nucleic acid binding,translation,translational initiation","GO:0005525,GO:0003924,GO:0005515,GO:0003743,GO:0008135,GO:0005829,GO:0006412,GO:0010467,GO:0044267,GO:0006184,GO:0006413","GTP binding,GTPase activity,protein binding,translation initiation factor activity,translation factor activity, nucleic acid binding,cytosol,translation,gene expression,cellular protein metabolic process,GTP catabolic process,translational initiation","."]
["AIMP1","aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 [Source:HGNC Symbol;Acc:10648]","ENSG00000164022","ENSP00000350699",2,"tRNA_bind[1],NUDE_C[1]","family-751","AIMP1",".",".","tRNA","putative tRNA","The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008]",".",".",".",".",".",".","GO:0000049,GO:0017101,GO:0006418","tRNA binding,aminoacyl-tRNA synthetase multienzyme complex,tRNA aminoacylation for protein translation","GO:0005515,GO:0042803,GO:0000049,GO:0005125,GO:0005634,GO:0016020,GO:0005829,GO:0005615,GO:0005783,GO:0009986,GO:0005794,GO:0017101,GO:0030133,GO:0006915,GO:0006954,GO:0001525,GO:0007155,GO:0007165,GO:0009611,GO:0010467,GO:0016192,GO:0006006,GO:0007267,GO:0006935,GO:0006418,GO:0050900,GO:0001937","protein binding,protein homodimerization activity,tRNA binding,cytokine activity,nucleus,membrane,cytosol,extracellular space,endoplasmic reticulum,cell surface,Golgi apparatus,aminoacyl-tRNA synthetase multienzyme complex,transport vesicle,apoptotic process,inflammatory response,angiogenesis,cell adhesion,signal transduction,response to wounding,gene expression,vesicle-mediated transport,glucose metabolic process,cell-cell signaling,chemotaxis,tRNA aminoacylation for protein translation,leukocyte migration,negative regulation of endothelial cell proliferation"," LEUKODYSTROPHY, HYPOMYELINATING, 3; HLD3"]
["APEX1","APEX nuclease (multifunctional DNA repair enzyme) 1 [Source:HGNC Symbol;Acc:587]","ENSG00000100823","ENSP00000452137",1,"Exo_endo_phos[1]","family-752","APEX1,APEX2","APEX1","APEX2[23,14]","mRNA","mRNA/rRNA","19401441, 19188445,11286553","nuclease",".",".",1,".",".","GO:0004521,GO:0003723,GO:0008408,GO:0004523,GO:0005840,GO:0043488","endoribonuclease activity,RNA binding,3'-5' exonuclease activity,ribonuclease H activity,ribosome,regulation of mRNA stability","GO:0004518,GO:0006281,GO:0003677,GO:0004519,GO:0005622,GO:0032403,GO:0004521,GO:0051059,GO:0005634,GO:0005667,GO:0005739,GO:0007568,GO:0042493,GO:0070301,GO:0071375,GO:0045454,GO:0071320,GO:0014912,GO:0005813,GO:0003723,GO:0003714,GO:0005515,GO:0016491,GO:0046872,GO:0008081,GO:0003684,GO:0003713,GO:0031490,GO:0008408,GO:0004520,GO:0004844,GO:0004523,GO:0003906,GO:0004528,GO:0016890,GO:0005737,GO:0048471,GO:0005783,GO:0005730,GO:0005840,GO:0005654,GO:0016607,GO:0006351,GO:0055114,GO:0006284,GO:0006355,GO:0006310,GO:0043488,GO:0045739,GO:0080111,GO:0071417,GO:1900087,GO:0010243","nuclease activity,DNA repair,DNA binding,endonuclease activity,intracellular,protein complex binding,endoribonuclease activity,NF-kappaB binding,nucleus,transcription factor complex,mitochondrion,aging,response to drug,cellular response to hydrogen peroxide,cellular response to peptide hormone stimulus,cell redox homeostasis,cellular response to cAMP,negative regulation of smooth muscle cell migration,centrosome,RNA binding,transcription corepressor activity,protein binding,oxidoreductase activity,metal ion binding,phosphoric diester hydrolase activity,damaged DNA binding,transcription coactivator activity,chromatin DNA binding,3'-5' exonuclease activity,endodeoxyribonuclease activity,uracil DNA N-glycosylase activity,ribonuclease H activity,DNA-(apurinic or apyrimidinic site) lyase activity,phosphodiesterase I activity,site-specific endodeoxyribonuclease activity, specific for altered base,cytoplasm,perinuclear region of cytoplasm,endoplasmic reticulum,nucleolus,ribosome,nucleoplasm,nuclear speck,transcription, DNA-templated,oxidation-reduction process,base-excision repair,regulation of transcription, DNA-dependent,DNA recombination,regulation of mRNA stability,positive regulation of DNA repair,DNA demethylation,cellular response to organonitrogen compound,positive regulation of G1/S transition of mitotic cell cycle,response to organonitrogen compound","."]
["EIF3J","eukaryotic translation initiation factor 3, subunit J [Source:HGNC Symbol;Acc:3270]","ENSG00000104131","ENSP00000443563",1,"eIF3_subunit[1]","family-753","EIF3J",".",".","mRNA","mRNA",17588516,".",".",".",".",1,".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006412,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translation,translational initiation","GO:0003743,GO:0005737,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0005515,GO:0005829,GO:0006412,GO:0010467,GO:0044267,GO:0006413","translation initiation factor activity,cytoplasm,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,protein binding,cytosol,translation,gene expression,cellular protein metabolic process,translational initiation","."]
["PABPC3","poly(A) binding protein, cytoplasmic 3 [Source:HGNC Symbol;Acc:8556]","ENSG00000151846","ENSP00000281589",5,"RRM_1[4],PABP[1]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA",11328870,".",".",".",".",".",1,"GO:0003723,GO:0008143,GO:0016071","RNA binding,poly(A) RNA binding,mRNA metabolic process","GO:0000166,GO:0003723,GO:0003676,GO:0008143,GO:0005737,GO:0016071","nucleotide binding,RNA binding,nucleic acid binding,poly(A) RNA binding,cytoplasm,mRNA metabolic process","."]
["PABPC1L","poly(A) binding protein, cytoplasmic 1-like [Source:HGNC Symbol;Acc:15797]","ENSG00000101104","ENSP00000217073",5,"RRM_1[4],PABP[1]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA",18716053,".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["PABPC1L2A","poly(A) binding protein, cytoplasmic 1-like 2A [Source:HGNC Symbol;Acc:27989]","ENSG00000268574","ENSP00000471407",2,"RRM_1[2]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["PABPC1L2B","poly(A) binding protein, cytoplasmic 1-like 2B [Source:HGNC Symbol;Acc:31852]","ENSG00000267891","ENSP00000470071",2,"RRM_1[2]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["PABPC4L","poly(A) binding protein, cytoplasmic 4-like [Source:HGNC Symbol;Acc:31955]","ENSG00000254535","ENSP00000462986",4,"RRM_1[4]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","by homology","RNAbinding",".",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["PABPC5","poly(A) binding protein, cytoplasmic 5 [Source:HGNC Symbol;Acc:13629]","ENSG00000174740","ENSP00000308012",4,"RRM_1[4]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005759","nucleotide binding,RNA binding,nucleic acid binding,mitochondrial matrix","."]
["PABPC4","poly(A) binding protein, cytoplasmic 4 (inducible form) [Source:HGNC Symbol;Acc:8557]","ENSG00000090621","ENSP00000361949",5,"RRM_1[4],PABP[1]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008143,GO:0008266,GO:0030529,GO:0010494,GO:0006412,GO:0006396,GO:0006401","RNA binding,poly(A) RNA binding,poly(U) RNA binding,ribonucleoprotein complex,cytoplasmic stress granule,translation,RNA processing,RNA catabolic process","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0008143,GO:0008266,GO:0005634,GO:0005737,GO:0030529,GO:0010494,GO:0006412,GO:0006396,GO:0007596,GO:0006401","nucleotide binding,nucleic acid binding,RNA binding,protein binding,poly(A) RNA binding,poly(U) RNA binding,nucleus,cytoplasm,ribonucleoprotein complex,cytoplasmic stress granule,translation,RNA processing,blood coagulation,RNA catabolic process","."]
["PABPC1","poly(A) binding protein, cytoplasmic 1 [Source:HGNC Symbol;Acc:8554]","ENSG00000070756","ENSP00000429395",5,"RRM_1[4],PABP[1]","family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","PABPC1","PABPC1L[68,70],PABPC3[92,93],PABPC4L[42,63],PABPC4[79,76],PABPC5[38,63],PABPC1L2A[25,80],PABPC1L2B[25,80]","mRNA","mRNA","This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008143,GO:0008494,GO:0030529,GO:0010494,GO:0071013,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0031047,GO:0060213,GO:1900153,GO:0000398,GO:0045727,GO:0006378,GO:0048255,GO:0006413,GO:0000184,GO:2000623","RNA binding,poly(A) RNA binding,translation activator activity,ribonucleoprotein complex,cytoplasmic stress granule,catalytic step 2 spliceosome,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA splicing, via spliceosome,positive regulation of translation,mRNA polyadenylation,mRNA stabilization,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0000166,GO:0003676,GO:0003723,GO:0005737,GO:0005515,GO:0008022,GO:0008143,GO:0008494,GO:0005634,GO:0005829,GO:0030529,GO:0010494,GO:0071013,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0031047,GO:0060213,GO:1900153,GO:0000398,GO:0045727,GO:0044267,GO:0006378,GO:0048255,GO:0006413,GO:0000184,GO:2000623","nucleotide binding,nucleic acid binding,RNA binding,cytoplasm,protein binding,protein C-terminus binding,poly(A) RNA binding,translation activator activity,nucleus,cytosol,ribonucleoprotein complex,cytoplasmic stress granule,catalytic step 2 spliceosome,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,gene silencing by RNA,positive regulation of nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA splicing, via spliceosome,positive regulation of translation,cellular protein metabolic process,mRNA polyadenylation,mRNA stabilization,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["MEX3A","mex-3 homolog A (C. elegans) [Source:HGNC Symbol;Acc:33482]","ENSG00000254726","ENSP00000432845",3,"KH_1[2],zf-C3HC4_3[1]","family-755","MEX3A,MEX3D,MEX3B,MEX3C","MEX3A","MEX3D[40,32],MEX3B[48,44],MEX3C[43,34]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0000932","RNA binding,cytoplasmic mRNA processing body","GO:0003723,GO:0005515,GO:0008270,GO:0005634,GO:0000932","RNA binding,protein binding,zinc ion binding,nucleus,cytoplasmic mRNA processing body","."]
["MEX3B","mex-3 homolog B (C. elegans) [Source:HGNC Symbol;Acc:25297]","ENSG00000183496","ENSP00000329918",3,"KH_1[2],zf-C3HC4_3[1]","family-755","MEX3A,MEX3D,MEX3B,MEX3C","MEX3A","MEX3D[40,32],MEX3B[48,44],MEX3C[43,34]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0000932","RNA binding,cytoplasmic mRNA processing body","GO:0003723,GO:0008270,GO:0005509,GO:0005634,GO:0005737,GO:0000932,GO:0006468,GO:0046777,GO:0005515","RNA binding,zinc ion binding,calcium ion binding,nucleus,cytoplasm,cytoplasmic mRNA processing body,protein phosphorylation,protein autophosphorylation,protein binding","."]
["MEX3C","mex-3 homolog C (C. elegans) [Source:HGNC Symbol;Acc:28040]","ENSG00000176624","ENSP00000385610",3,"KH_1[2],zf-C3HC4_3[1]","family-755","MEX3A,MEX3D,MEX3B,MEX3C","MEX3A","MEX3D[40,32],MEX3B[48,44],MEX3C[43,34]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0008270,GO:0016874,GO:0005634,GO:0005737,GO:0043231,GO:0097009,GO:0045598,GO:0003415","RNA binding,protein binding,zinc ion binding,ligase activity,nucleus,cytoplasm,intracellular membrane-bounded organelle,energy homeostasis,regulation of fat cell differentiation,chondrocyte hypertrophy","."]
["MEX3D","mex-3 homolog D (C. elegans) [Source:HGNC Symbol;Acc:16734]","ENSG00000181588","ENSP00000384398",3,"KH_1[2],zf-C3HC4_3[1]","family-755","MEX3A,MEX3D,MEX3B,MEX3C","MEX3A","MEX3D[40,32],MEX3B[48,44],MEX3C[43,34]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0017091,GO:0061157,GO:0010609","RNA binding,AU-rich element binding,mRNA destabilization,mRNA localization resulting in posttranscriptional regulation of gene expression","GO:0003723,GO:0005515,GO:0008270,GO:0017091,GO:0005634,GO:0048471,GO:0061157,GO:0010609","RNA binding,protein binding,zinc ion binding,AU-rich element binding,nucleus,perinuclear region of cytoplasm,mRNA destabilization,mRNA localization resulting in posttranscriptional regulation of gene expression","."]
["GEMIN7","gem (nuclear organelle) associated protein 7 [Source:HGNC Symbol;Acc:20045]","ENSG00000142252","ENSP00000466342",2,"SUZ-C[1],Gemin7[1]","family-756","GEMIN7",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005681,GO:0032797,GO:0016070,GO:0000398,GO:0000387,GO:0034660","spliceosomal complex,SMN complex,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,ncRNA metabolic process","GO:0005515,GO:0005737,GO:0005829,GO:0005654,GO:0005681,GO:0016604,GO:0097504,GO:0032797,GO:0010467,GO:0016070,GO:0000398,GO:0000387,GO:0034660","protein binding,cytoplasm,cytosol,nucleoplasm,spliceosomal complex,nuclear body,Gemini of coiled bodies,SMN complex,gene expression,RNA metabolic process,mRNA splicing, via spliceosome,spliceosomal snRNP assembly,ncRNA metabolic process","."]
["MRPS23","mitochondrial ribosomal protein S23 [Source:HGNC Symbol;Acc:14509]","ENSG00000181610","ENSP00000320184",1,"MRP-S23[1]","family-757","MRPS23",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005840,GO:0006412,GO:0005739,GO:0031965,GO:0045111","structural constituent of ribosome,ribosome,translation,mitochondrion,nuclear membrane,intermediate filament cytoskeleton","."]
["PSIP1","PC4 and SFRS1 interacting protein 1 [Source:HGNC Symbol;Acc:9527]","ENSG00000164985","ENSP00000370109",2,"LEDGF[1],PWWP[1]","family-758","HDGF,HDGFL1,HDGFRP3,HDGFRP2,PSIP1","HDGF","HDGFL1[48,49],HDGFRP3[29,36],HDGFRP2[36,13],PSIP1[32,15]","mRNA","putative mRNA",22615581,"candidate mRNA binder","novel",1,1,".",".","GO:0000395","mRNA 5'-splice site recognition","GO:0005515,GO:0003682,GO:0033613,GO:0001105,GO:0097100,GO:0005634,GO:0005829,GO:0005654,GO:0034399,GO:0005720,GO:0035327,GO:0006351,GO:0045944,GO:0006979,GO:0006355,GO:0016032,GO:0009408,GO:0019048,GO:0000395,GO:0075713","protein binding,chromatin binding,activating transcription factor binding,RNA polymerase II transcription coactivator activity,supercoiled DNA binding,nucleus,cytosol,nucleoplasm,nuclear periphery,nuclear heterochromatin,transcriptionally active chromatin,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,response to oxidative stress,regulation of transcription, DNA-dependent,viral process,response to heat,modulation by virus of host morphology or physiology,mRNA 5'-splice site recognition,establishment of integrated proviral latency","."]
["SRP54","signal recognition particle 54kDa [Source:HGNC Symbol;Acc:11301]","ENSG00000100883","ENSP00000216774",3,"SRP_SPB[1],SRP54[1],SRP54_N[1]","family-759","SRP54",".",".","ncRNA","7SL","doi:10.1038/nrg2843, 11680843",".","RNAbinding",".",1,".",".","GO:0043021,GO:0008312,GO:0006412","ribonucleoprotein complex binding,7S RNA binding,translation","GO:0000166,GO:0005525,GO:0003924,GO:0017111,GO:0008144,GO:0043021,GO:0019003,GO:0008312,GO:0030942,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0016607,GO:0048500,GO:0005786,GO:0006412,GO:0042493,GO:0010467,GO:0044267,GO:0006614,GO:0006184,GO:0045047,GO:0006616,GO:0006617","nucleotide binding,GTP binding,GTPase activity,nucleoside-triphosphatase activity,drug binding,ribonucleoprotein complex binding,GDP binding,7S RNA binding,endoplasmic reticulum signal peptide binding,nucleus,cytoplasm,cytosol,nucleolus,nuclear speck,signal recognition particle,signal recognition particle, endoplasmic reticulum targeting,translation,response to drug,gene expression,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,GTP catabolic process,protein targeting to ER,SRP-dependent cotranslational protein targeting to membrane, translocation,SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition","."]
["FARSB","phenylalanyl-tRNA synthetase, beta subunit [Source:HGNC Symbol;Acc:17800]","ENSG00000116120","ENSP00000281828",2,"B3_4[1],B5[1]","family-76","FARSB",".",".","tRNA","tRNA","established RBP ",".",".",".",".",1,".","GO:0003723,GO:0004826,GO:0006432,GO:0006412,GO:0006418","RNA binding,phenylalanine-tRNA ligase activity,phenylalanyl-tRNA aminoacylation,translation,tRNA aminoacylation for protein translation","GO:0000166,GO:0003723,GO:0005524,GO:0000287,GO:0004826,GO:0005737,GO:0006432,GO:0005829,GO:0006412,GO:0010467,GO:0006418","nucleotide binding,RNA binding,ATP binding,magnesium ion binding,phenylalanine-tRNA ligase activity,cytoplasm,phenylalanyl-tRNA aminoacylation,cytosol,translation,gene expression,tRNA aminoacylation for protein translation","."]
["SPEN","spen homolog, transcriptional regulator (Drosophila) [Source:HGNC Symbol;Acc:17575]","ENSG00000065526","ENSP00000364912",5,"RRM_5[1],RRM_1[3],SPOC[1]","family-760","RBM15,RBM15B,SPEN","RBM15","RBM15B[40,44],SPEN[23,6]","mRNA","putative mRNA",21637295,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0003676,GO:0000166,GO:0005515,GO:0003723,GO:0003700,GO:0003714,GO:0003697,GO:0001085,GO:0001191,GO:0005634,GO:0017053,GO:0045892,GO:0000122,GO:0045893,GO:0007219,GO:0050769,GO:0019048","nucleic acid binding,nucleotide binding,protein binding,RNA binding,sequence-specific DNA binding transcription factor activity,transcription corepressor activity,single-stranded DNA binding,RNA polymerase II transcription factor binding,RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription,nucleus,transcriptional repressor complex,negative regulation of transcription, DNA-dependent,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription, DNA-dependent,Notch signaling pathway,positive regulation of neurogenesis,modulation by virus of host morphology or physiology","."]
["RBM15B","RNA binding motif protein 15B [Source:HGNC Symbol;Acc:24303]","ENSG00000179837","ENSP00000313890",4,"RRM_5[1],RRM_1[2],SPOC[1]","family-760","RBM15,RBM15B,SPEN","RBM15","RBM15B[40,44],SPEN[23,6]","mRNA","mRNA"," 19586903, Members of the SPEN (Split-end) family of proteins, including RBM15B, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0000381","RNA binding,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005654,GO:0006351,GO:0006397,GO:0008380,GO:0000381,GO:0019048","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,nucleoplasm,transcription, DNA-templated,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,modulation by virus of host morphology or physiology","."]
["RBM15","RNA binding motif protein 15 [Source:HGNC Symbol;Acc:14959]","ENSG00000162775","ENSP00000473638",4,"RRM_5[2],RRM_1[1],SPOC[1]","family-760","RBM15,RBM15B,SPEN","RBM15","RBM15B[40,44],SPEN[23,6]","mRNA","mRNA","Members of the SPEN (Split-end) family of proteins, including RBM15, have repressor function in several signaling pathways and may bind to RNA through interaction with spliceosome components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by OMIM, Feb 2009]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0060674,GO:0001569,GO:0048536,GO:0060412,GO:0045638,GO:0019048,GO:0007221,GO:0000122","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,placenta blood vessel development,patterning of blood vessels,spleen development,ventricular septum morphogenesis,negative regulation of myeloid cell differentiation,modulation by virus of host morphology or physiology,positive regulation of transcription of Notch receptor target,negative regulation of transcription from RNA polymerase II promoter","."]
["DNAAF2","dynein, axonemal, assembly factor 2 [Source:HGNC Symbol;Acc:20188]","ENSG00000165506","ENSP00000384862",1,"PIH1[1]","family-761","DNAAF2",".",".","unknown","unknown","by domain",".",".",".",".",".",".",".",".","GO:0005737,GO:0032526,GO:0060285,GO:0070286,GO:0071973,GO:0005515,GO:0010033","cytoplasm,response to retinoic acid,ciliary cell motility,axonemal dynein complex assembly,bacterial-type flagellar cell motility,protein binding,response to organic substance"," CILIARY DYSKINESIA, PRIMARY, 10; CILD10"]
["SF3B1","splicing factor 3b, subunit 1, 155kDa [Source:HGNC Symbol;Acc:10768]","ENSG00000115524","ENSP00000335321",2,"HEAT_2[1],SF3b1[1]","family-762","SF3B1",".",".","mRNA","mRNA","This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]","RNAbinding","RNArelated",1,1,".",".","GO:0005681,GO:0005689,GO:0071013,GO:0008380,GO:0000398,GO:0000375","spliceosomal complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0003682,GO:0009952,GO:0005515,GO:0005634,GO:0005654,GO:0005681,GO:0016607,GO:0005689,GO:0071013,GO:0010467,GO:0008380,GO:0000398,GO:0000375,GO:0005488","chromatin binding,anterior/posterior pattern specification,protein binding,nucleus,nucleoplasm,spliceosomal complex,nuclear speck,U12-type spliceosomal complex,catalytic step 2 spliceosome,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,binding","."]
["RNASEH2B","ribonuclease H2, subunit B [Source:HGNC Symbol;Acc:25671]","ENSG00000136104","ENSP00000337623",1,"RNase_H2-Ydr279[1]","family-763","RNASEH2B",".",".","diverse","RNA/DNA","established RBP ",".",".",".",".",".",".","GO:0004523,GO:0032299,GO:0009259,GO:0006401","ribonuclease H activity,ribonuclease H2 complex,ribonucleotide metabolic process,RNA catabolic process","GO:0005634,GO:0004523,GO:0032299,GO:0001701,GO:0010629,GO:0010389,GO:0048146,GO:0009259,GO:2000001,GO:0006401","nucleus,ribonuclease H activity,ribonuclease H2 complex,in utero embryonic development,negative regulation of gene expression,regulation of G2/M transition of mitotic cell cycle,positive regulation of fibroblast proliferation,ribonucleotide metabolic process,regulation of DNA damage checkpoint,RNA catabolic process"," AICARDI-GOUTIERES SYNDROME 2; AGS2"]
["FARSA","phenylalanyl-tRNA synthetase, alpha subunit [Source:HGNC Symbol;Acc:3592]","ENSG00000179115","ENSP00000467384",2,"MarR_2[1],tRNA-synt_2d[1]","family-764","FARSA",".",".","tRNA","tRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0000049,GO:0004812,GO:0004826,GO:0006418,GO:0006432,GO:0043039","tRNA binding,aminoacyl-tRNA ligase activity,phenylalanine-tRNA ligase activity,tRNA aminoacylation for protein translation,phenylalanyl-tRNA aminoacylation,tRNA aminoacylation","GO:0000166,GO:0005524,GO:0000049,GO:0004812,GO:0004826,GO:0005737,GO:0006418,GO:0006432,GO:0043039,GO:0005515,GO:0005829,GO:0010467","nucleotide binding,ATP binding,tRNA binding,aminoacyl-tRNA ligase activity,phenylalanine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,phenylalanyl-tRNA aminoacylation,tRNA aminoacylation,protein binding,cytosol,gene expression","."]
["NOB1","NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29540]","ENSG00000141101","ENSP00000268802",2,"AF1Q[1],NOB1_Zn_bind[1]","family-765","NOB1",".",".","rRNA","putative rRNA","In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM, Nov 2010]",".",".",".",".",".",".",".",".","GO:0046872,GO:0005634,GO:0007601","metal ion binding,nucleus,visual perception","."]
["EIF2A","eukaryotic translation initiation factor 2A, 65kDa [Source:HGNC Symbol;Acc:3254]","ENSG00000144895","ENSP00000385292",1,"eIF2A[1]","family-766","EIF2A",".",".","tRNA","tRNA/mRNA",12133843,".",".",".",".",".",".","GO:0000049,GO:0003743,GO:0043022,GO:0005850,GO:0006417,GO:0042255,GO:0006412","tRNA binding,translation initiation factor activity,ribosome binding,eukaryotic translation initiation factor 2 complex,regulation of translation,ribosome assembly,translation","GO:0005515,GO:0000049,GO:0003743,GO:0043022,GO:0005737,GO:0005850,GO:0006417,GO:0006468,GO:0042255,GO:0009967,GO:0032933,GO:0006412","protein binding,tRNA binding,translation initiation factor activity,ribosome binding,cytoplasm,eukaryotic translation initiation factor 2 complex,regulation of translation,protein phosphorylation,ribosome assembly,positive regulation of signal transduction,SREBP signaling pathway,translation","."]
["RNASEL","ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) [Source:HGNC Symbol;Acc:10050]","ENSG00000135828","ENSP00000356530",6,"Ank_2[2],Pkinase[1],Ank_5[1],Ribonuc_2-5A[1],Ank_4[1]","family-767","RNASEL",".",".","ncRNA","viral RNA","This gene encodes a component of the interferon-regulated 2-5A system that functions in the antiviral and antiproliferative roles of interferons. Mutations in this gene have been associated with predisposition to prostate cancer and this gene is a candidate for the hereditary prostate cancer 1 (HPC1) allele. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0004540,GO:0006397,GO:0003723,GO:0004521,GO:0019843,GO:0006364","ribonuclease activity,mRNA processing,RNA binding,endoribonuclease activity,rRNA binding,rRNA processing","GO:0005515,GO:0005524,GO:0004672,GO:0016773,GO:0004540,GO:0016772,GO:0016020,GO:0006397,GO:0006468,GO:0009103,GO:0003723,GO:0046872,GO:0004521,GO:0005739,GO:0005829,GO:0045944,GO:0045071,GO:0019221,GO:0051607,GO:0060337,GO:0019843,GO:0016363,GO:0006364","protein binding,ATP binding,protein kinase activity,phosphotransferase activity, alcohol group as acceptor,ribonuclease activity,transferase activity, transferring phosphorus-containing groups,membrane,mRNA processing,protein phosphorylation,lipopolysaccharide biosynthetic process,RNA binding,metal ion binding,endoribonuclease activity,mitochondrion,cytosol,positive regulation of transcription from RNA polymerase II promoter,negative regulation of viral genome replication,cytokine-mediated signaling pathway,defense response to virus,type I interferon signaling pathway,rRNA binding,nuclear matrix,rRNA processing"," PROSTATE CANCER"]
["TRNT1","tRNA nucleotidyl transferase, CCA-adding, 1 [Source:HGNC Symbol;Acc:17341]","ENSG00000072756","ENSP00000251607",2,"PolyA_pol[1],PolyA_pol_RNAbd[1]","family-768","TRNT1",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0009022,GO:0042780,GO:0000049,GO:0004810,GO:0052927,GO:0052928,GO:0052929,GO:0001680,GO:0003723,GO:0006396","tRNA nucleotidyltransferase activity,tRNA 3'-end processing,tRNA binding,tRNA adenylyltransferase activity,CTP:tRNA cytidylyltransferase activity,CTP:3'-cytidine-tRNA cytidylyltransferase activity,ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity,tRNA 3'-terminal CCA addition,RNA binding,RNA processing","GO:0009022,GO:0042780,GO:0005524,GO:0000049,GO:0004810,GO:0052927,GO:0052928,GO:0052929,GO:0005739,GO:0005622,GO:0005813,GO:0006626,GO:0001680,GO:0003723,GO:0016779,GO:0006396","tRNA nucleotidyltransferase activity,tRNA 3'-end processing,ATP binding,tRNA binding,tRNA adenylyltransferase activity,CTP:tRNA cytidylyltransferase activity,CTP:3'-cytidine-tRNA cytidylyltransferase activity,ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity,mitochondrion,intracellular,centrosome,protein targeting to mitochondrion,tRNA 3'-terminal CCA addition,RNA binding,nucleotidyltransferase activity,RNA processing","."]
["EIF4ENIF1","eukaryotic translation initiation factor 4E nuclear import factor 1 [Source:HGNC Symbol;Acc:16687]","ENSG00000184708","ENSP00000328103",1,"EIF4E-T[1]","family-769","EIF4ENIF1",".",".","mRNA","putative mRNA","The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]","translationfactor",".",".",1,1,".","GO:0003743","translation initiation factor activity","GO:0003743,GO:0043231,GO:0005634,GO:0005829,GO:0005515,GO:0008565,GO:0005737,GO:0016605,GO:0016607","translation initiation factor activity,intracellular membrane-bounded organelle,nucleus,cytosol,protein binding,protein transporter activity,cytoplasm,PML body,nuclear speck","."]
["MECP2","methyl CpG binding protein 2 (Rett syndrome) [Source:HGNC Symbol;Acc:6990]","ENSG00000169057","ENSP00000301948",1,"MBD[1]","family-77","MECP2",".",".","mRNA","mRNA",21070191,".","RNAbinding",".",1,".",".","GO:0003729,GO:0035197","mRNA binding,siRNA binding","GO:0003677,GO:0005634,GO:0005515,GO:0010385,GO:0003700,GO:0003714,GO:0019904,GO:0003682,GO:0003729,GO:0008134,GO:0047485,GO:0035197,GO:0008327,GO:0005737,GO:0000792,GO:0005829,GO:0031175,GO:0007420,GO:0045892,GO:0010468,GO:0040029,GO:0007268,GO:0007612,GO:0050905,GO:0030182,GO:0050884,GO:0007613,GO:0048167,GO:0033555,GO:0006576,GO:0000122,GO:0006351,GO:0045893,GO:0001964,GO:0008284,GO:0001666,GO:0009790,GO:0009791,GO:0001662,GO:0035176,GO:0060291,GO:0006541,GO:0060079,GO:0008104,GO:0016358,GO:0021591,GO:0043524,GO:0019233,GO:0051965,GO:0008344,GO:0007616,GO:0008542,GO:0006122,GO:0002087,GO:0042551,GO:0006349,GO:0035067,GO:0021549,GO:0016571,GO:0019230,GO:0007585,GO:0007416,GO:0016573,GO:0008211,GO:0009405,GO:0006342,GO:0006020,GO:0046470,GO:0001976,GO:0031061,GO:0032048,GO:0050432","DNA binding,nucleus,protein binding,double-stranded methylated DNA binding,sequence-specific DNA binding transcription factor activity,transcription corepressor activity,protein domain specific binding,chromatin binding,mRNA binding,transcription factor binding,protein N-terminus binding,siRNA binding,methyl-CpG binding,cytoplasm,heterochromatin,cytosol,neuron projection development,brain development,negative regulation of transcription, DNA-dependent,regulation of gene expression,regulation of gene expression, epigenetic,synaptic transmission,learning,neuromuscular process,neuron differentiation,neuromuscular process controlling posture,memory,regulation of synaptic plasticity,multicellular organismal response to stress,cellular biogenic amine metabolic process,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of transcription, DNA-dependent,startle response,positive regulation of cell proliferation,response to hypoxia,embryo development,post-embryonic development,behavioral fear response,social behavior,long-term synaptic potentiation,glutamine metabolic process,regulation of excitatory postsynaptic membrane potential,protein localization,dendrite development,ventricular system development,negative regulation of neuron apoptotic process,sensory perception of pain,positive regulation of synapse assembly,adult locomotory behavior,long-term memory,visual learning,mitochondrial electron transport, ubiquinol to cytochrome c,regulation of respiratory gaseous exchange by neurological system process,neuron maturation,regulation of gene expression by genetic imprinting,negative regulation of histone acetylation,cerebellum development,histone methylation,proprioception,respiratory gaseous exchange,synapse assembly,histone acetylation,glucocorticoid metabolic process,pathogenesis,chromatin silencing,inositol metabolic process,phosphatidylcholine metabolic process,neurological system process involved in regulation of systemic arterial blood pressure,negative regulation of histone methylation,cardiolipin metabolic process,catecholamine secretion"," ANGELMAN SYNDROME; AS"]
["RBM22","RNA binding motif protein 22 [Source:HGNC Symbol;Acc:25503]","ENSG00000086589","ENSP00000199814",3,"FYVE[1],RRM_1[1],zf-CCCH[1]","family-770","RBM22",".",".","mRNA","putative mRNA","by homology, ECM2, This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0017069,GO:0036002,GO:0071013,GO:0000398,GO:0045292,GO:0033120","RNA binding,snRNA binding,pre-mRNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,mRNA cis splicing, via spliceosome,positive regulation of RNA splicing","GO:0000166,GO:0003723,GO:0003676,GO:0046872,GO:0005634,GO:0048306,GO:0005487,GO:0017069,GO:0036002,GO:0005737,GO:0071013,GO:0000398,GO:0045292,GO:0035690,GO:0000060,GO:0090316,GO:0033120,GO:0008270","nucleotide binding,RNA binding,nucleic acid binding,metal ion binding,nucleus,calcium-dependent protein binding,nucleocytoplasmic transporter activity,snRNA binding,pre-mRNA binding,cytoplasm,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,mRNA cis splicing, via spliceosome,cellular response to drug,protein import into nucleus, translocation,positive regulation of intracellular protein transport,positive regulation of RNA splicing,zinc ion binding","."]
["CMTR1","cap methyltransferase 1 [Source:HGNC Symbol;Acc:21077]","ENSG00000137200","ENSP00000414233",2,"G-patch[1],FtsJ[1]","family-771","CMTR1",".",".","mRNA","mRNA",20713356,".",".",".",".",".",".","GO:0004483,GO:0006370,GO:0080009","mRNA (nucleoside-2'-O-)-methyltransferase activity,7-methylguanosine mRNA capping,mRNA methylation","GO:0005515,GO:0003676,GO:0008168,GO:0004483,GO:0005634,GO:0005737,GO:0006370,GO:0032259,GO:0080009,GO:0097309","protein binding,nucleic acid binding,methyltransferase activity,mRNA (nucleoside-2'-O-)-methyltransferase activity,nucleus,cytoplasm,7-methylguanosine mRNA capping,methylation,mRNA methylation,cap1 mRNA methylation","."]
["RPL39","ribosomal protein L39 [Source:HGNC Symbol;Acc:10350]","ENSG00000198918","ENSP00000355315",1,"Ribosomal_L39[1]","family-772","RPL39,RPL39L","RPL39","RPL39L[92,92]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL39L","ribosomal protein L39-like [Source:HGNC Symbol;Acc:17094]","ENSG00000163923","ENSP00000389356",1,"Ribosomal_L39[1]","family-772","RPL39,RPL39L","RPL39","RPL39L[92,92]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0022625,GO:0006412","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation","GO:0003735,GO:0005622,GO:0005840,GO:0022625,GO:0007283,GO:0006412","structural constituent of ribosome,intracellular,ribosome,cytosolic large ribosomal subunit,spermatogenesis,translation","."]
["RPSA","ribosomal protein SA [Source:HGNC Symbol;Acc:6502]","ENSG00000168028","ENSP00000410848",1,"Ribosomal_S2[1]","family-773","RPSA,RPSAP58","RPSA","RPSAP58[99,99]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0043022,GO:0022627,GO:0005840,GO:0015935,GO:0030686,GO:0000028,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0000447,GO:0006415,GO:0000461,GO:0006407","structural constituent of ribosome,ribosome binding,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,90S preribosome,ribosomal small subunit assembly,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),translational termination,endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),rRNA export from nucleus","GO:0005515,GO:0003735,GO:0005055,GO:0043236,GO:0043022,GO:0005634,GO:0005886,GO:0005737,GO:0005829,GO:0005622,GO:0022627,GO:0005840,GO:0015935,GO:0030686,GO:0000028,GO:0006412,GO:0007155,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0000447,GO:0006415,GO:0019083,GO:0000461,GO:0006407","protein binding,structural constituent of ribosome,laminin receptor activity,laminin binding,ribosome binding,nucleus,plasma membrane,cytoplasm,cytosol,intracellular,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,90S preribosome,ribosomal small subunit assembly,translation,cell adhesion,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),translational termination,viral transcription,endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),rRNA export from nucleus","."]
["PARP4","poly (ADP-ribose) polymerase family, member 4 [Source:HGNC Symbol;Acc:271]","ENSG00000102699","ENSP00000371419",5,"BRCT[1],VWA_3[1],PARP_reg[1],VIT[1],PARP[1]","family-774","PARP4,VWA5A","PARP4","VWA5A[10,22]","ncRNA","vtRNA",11479319,".",".",".",".",".",".","GO:0030529","ribonucleoprotein complex","GO:0005515,GO:0003677,GO:0019899,GO:0003950,GO:0005634,GO:0005737,GO:0030529,GO:0005876,GO:0006954,GO:0006974,GO:0006464,GO:0042493,GO:0006281,GO:0006810,GO:0006471,GO:0008219","protein binding,DNA binding,enzyme binding,NAD+ ADP-ribosyltransferase activity,nucleus,cytoplasm,ribonucleoprotein complex,spindle microtubule,inflammatory response,cellular response to DNA damage stimulus,cellular protein modification process,response to drug,DNA repair,transport,protein ADP-ribosylation,cell death","."]
["CSTF1","cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa [Source:HGNC Symbol;Acc:2483]","ENSG00000101138","ENSP00000217109",4,"WD40[4]","family-775","CSTF1,SPAG16","CSTF1","SPAG16[20,13]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0003723,GO:0008380,GO:0000398,GO:0006396,GO:0006379,GO:0031124,GO:0006378","RNA binding,RNA splicing,mRNA splicing, via spliceosome,RNA processing,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation","GO:0005515,GO:0003723,GO:0005634,GO:0005654,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0006379,GO:0031124,GO:0006378,GO:0006369","protein binding,RNA binding,nucleus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,mRNA cleavage,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription","."]
["NCBP1","nuclear cap binding protein subunit 1, 80kDa [Source:HGNC Symbol;Acc:7658]","ENSG00000136937","ENSP00000364289",3,"MIF4G_like_2[1],MIF4G[1],MIF4G_like[1]","family-776","NCBP1",".",".","mRNA","mRNA","The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]","RNAbinding",".",".",1,".",".","GO:0016070,GO:0000339,GO:0051028,GO:0045292,GO:0003723,GO:0030529,GO:0005845,GO:0016071,GO:0031047,GO:0008380,GO:0000398,GO:0006379,GO:0006446,GO:0006370,GO:0006406,GO:0031124,GO:0000387,GO:0034660,GO:0000184,GO:0008334,GO:0031442","RNA metabolic process,RNA cap binding,mRNA transport,mRNA cis splicing, via spliceosome,RNA binding,ribonucleoprotein complex,mRNA cap binding complex,mRNA metabolic process,gene silencing by RNA,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,regulation of translational initiation,7-methylguanosine mRNA capping,mRNA export from nucleus,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,histone mRNA metabolic process,positive regulation of mRNA 3'-end processing","GO:0005488,GO:0016070,GO:0000339,GO:0005846,GO:0051028,GO:0045292,GO:0005515,GO:0003723,GO:0005634,GO:0005829,GO:0005654,GO:0030529,GO:0005845,GO:0006366,GO:0016032,GO:0010467,GO:0016071,GO:0031047,GO:0008380,GO:0000398,GO:0006379,GO:0006446,GO:0006368,GO:0006370,GO:0006406,GO:0031124,GO:0000387,GO:0050434,GO:0034660,GO:0000184,GO:0006369,GO:0008334,GO:0031442","binding,RNA metabolic process,RNA cap binding,nuclear cap binding complex,mRNA transport,mRNA cis splicing, via spliceosome,protein binding,RNA binding,nucleus,cytosol,nucleoplasm,ribonucleoprotein complex,mRNA cap binding complex,transcription from RNA polymerase II promoter,viral process,gene expression,mRNA metabolic process,gene silencing by RNA,RNA splicing,mRNA splicing, via spliceosome,mRNA cleavage,regulation of translational initiation,transcription elongation from RNA polymerase II promoter,7-methylguanosine mRNA capping,mRNA export from nucleus,mRNA 3'-end processing,spliceosomal snRNP assembly,positive regulation of viral transcription,ncRNA metabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription,histone mRNA metabolic process,positive regulation of mRNA 3'-end processing","."]
["SNRNP25","small nuclear ribonucleoprotein 25kDa (U11/U12) [Source:HGNC Symbol;Acc:14161]","ENSG00000161981","ENSP00000372482",".",".","family-777","SNRNP25",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005689,GO:0006397,GO:0008380","U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0005515,GO:0005634,GO:0005689,GO:0006397,GO:0008380","protein binding,nucleus,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["DNAJC21","DnaJ (Hsp40) homolog, subfamily C, member 21 [Source:HGNC Symbol;Acc:27030]","ENSG00000168724","ENSP00000306289",3,"zf-C2H2_jaz[1],DnaJ[1],zf-C2H2_2[1]","family-778","DNAJC21",".",".","unknown","unknown","by domain",".","RNArelated",".",1,".",".","GO:0005840","ribosome","GO:0005515,GO:0008270,GO:0003676,GO:0046872,GO:0005840,GO:0006457","protein binding,zinc ion binding,nucleic acid binding,metal ion binding,ribosome,protein folding","."]
["CWC22","CWC22 spliceosome-associated protein homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29322]","ENSG00000163510","ENSP00000295749",3,"MIF4G[1],MA3[1],CAF-1_p150[1]","family-779","CWC22",".",".","mRNA","mRNA",22959432,".",".",".",".",".",".","GO:0003723,GO:0005681,GO:0071013,GO:0000398,GO:0048024","RNA binding,spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,regulation of mRNA splicing, via spliceosome","GO:0003723,GO:0005515,GO:0005488,GO:0005634,GO:0005737,GO:0005681,GO:0016607,GO:0071013,GO:0000398,GO:0048024","RNA binding,protein binding,binding,nucleus,cytoplasm,spliceosomal complex,nuclear speck,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,regulation of mRNA splicing, via spliceosome","."]
["NFX1","nuclear transcription factor, X-box binding 1 [Source:HGNC Symbol;Acc:7803]","ENSG00000086102","ENSP00000368856",8,"R3H[1],zf-NF-X1[7]","family-78","NFX1,NFXL1","NFX1","NFXL1[22,27]","mRNA","mRNA",19369336,"candidate mRNA binder","RNArelated",1,1,".",".",".",".","GO:0003700,GO:0005515,GO:0008270,GO:0016874,GO:0003677,GO:0005634,GO:0000122,GO:0006954,GO:0006366,GO:0006355,GO:0019048,GO:0045347,GO:0003676","sequence-specific DNA binding transcription factor activity,protein binding,zinc ion binding,ligase activity,DNA binding,nucleus,negative regulation of transcription from RNA polymerase II promoter,inflammatory response,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,modulation by virus of host morphology or physiology,negative regulation of MHC class II biosynthetic process,nucleic acid binding","."]
["MRPS31","mitochondrial ribosomal protein S31 [Source:HGNC Symbol;Acc:16632]","ENSG00000102738","ENSP00000315397",1,"MRP-S31[1]","family-780","MRPS31",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,1,".","GO:0003735,GO:0005763","structural constituent of ribosome,mitochondrial small ribosomal subunit","GO:0005515,GO:0019904,GO:0003735,GO:0005739,GO:0005763","protein binding,protein domain specific binding,structural constituent of ribosome,mitochondrion,mitochondrial small ribosomal subunit","."]
["SMG5","smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:24644]","ENSG00000198952","ENSP00000355261",4,"PIN_4[1],EST1_DNA_bind[2],EST1[1]","family-781","SMG5",".",".","mRNA","mRNA","This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]",".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0006406,GO:0000184","RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0051721,GO:0005634,GO:0005737,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0006406,GO:0000184,GO:0035303","protein binding,protein phosphatase 2A binding,nucleus,cytoplasm,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of dephosphorylation","."]
["SART1","squamous cell carcinoma antigen recognized by T cells [Source:HGNC Symbol;Acc:10538]","ENSG00000175467","ENSP00000310448",1,"SART-1[1]","family-782","SART1",".",".","snRNA","snRNA","The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]","candidate mRNA binder","RNArelated",1,1,".",".","GO:0071013,GO:0000398,GO:0000387","catalytic step 2 spliceosome,mRNA splicing, via spliceosome,spliceosomal snRNP assembly","GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005794,GO:0005654,GO:0015030,GO:0071013,GO:0000398,GO:0007050,GO:0097193,GO:0000387,GO:0045585","protein binding,nucleus,cytoplasm,cytosol,Golgi apparatus,nucleoplasm,Cajal body,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,cell cycle arrest,intrinsic apoptotic signaling pathway,spliceosomal snRNP assembly,positive regulation of cytotoxic T cell differentiation","."]
["GEMIN2","gem (nuclear organelle) associated protein 2 [Source:HGNC Symbol;Acc:10884]","ENSG00000092208","ENSP00000308533",1,"SIP1[1]","family-783","GEMIN2",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0005681,GO:0016070,GO:0006397,GO:0008380,GO:0000245,GO:0000387,GO:0000375,GO:0034660","spliceosomal complex,RNA metabolic process,mRNA processing,RNA splicing,spliceosomal complex assembly,spliceosomal snRNP assembly,RNA splicing, via transesterification reactions,ncRNA metabolic process","GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005681,GO:0097504,GO:0010467,GO:0016070,GO:0006397,GO:0008380,GO:0000245,GO:0000387,GO:0000375,GO:0034660,GO:0005622","protein binding,nucleus,cytoplasm,cytosol,nucleoplasm,spliceosomal complex,Gemini of coiled bodies,gene expression,RNA metabolic process,mRNA processing,RNA splicing,spliceosomal complex assembly,spliceosomal snRNP assembly,RNA splicing, via transesterification reactions,ncRNA metabolic process,intracellular","."]
["NR0B1","nuclear receptor subfamily 0, group B, member 1 [Source:HGNC Symbol;Acc:7960]","ENSG00000169297","ENSP00000368253",5,"Hormone_recep[1],NR_Repeat[4]","family-784","NR0B1,NR0B2","NR0B1","NR0B2[21,39]","mRNA","mRNA",10848616,".",".",".",".",".",".","GO:0003723,GO:0042788","RNA binding,polysomal ribosome","GO:0003723,GO:0003700,GO:0003714,GO:0005515,GO:0042803,GO:0003677,GO:0019904,GO:0043565,GO:0003707,GO:0008134,GO:0004879,GO:0032448,GO:0035258,GO:0050682,GO:0005634,GO:0005737,GO:0016020,GO:0005654,GO:0042788,GO:0000122,GO:0006351,GO:0007283,GO:0045892,GO:0043433,GO:0006355,GO:0045596,GO:0010467,GO:0021854,GO:0008584,GO:0006950,GO:0006694,GO:0006367,GO:0008104,GO:0030325,GO:0021983,GO:0060008,GO:0030238,GO:0033327,GO:0033144,GO:0008406,GO:0043401,GO:0030522,GO:0007530,GO:0030154,GO:0035902","RNA binding,sequence-specific DNA binding transcription factor activity,transcription corepressor activity,protein binding,protein homodimerization activity,DNA binding,protein domain specific binding,sequence-specific DNA binding,steroid hormone receptor activity,transcription factor binding,ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity,DNA hairpin binding,steroid hormone receptor binding,AF-2 domain binding,nucleus,cytoplasm,membrane,nucleoplasm,polysomal ribosome,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,spermatogenesis,negative regulation of transcription, DNA-dependent,negative regulation of sequence-specific DNA binding transcription factor activity,regulation of transcription, DNA-dependent,negative regulation of cell differentiation,gene expression,hypothalamus development,male gonad development,response to stress,steroid biosynthetic process,transcription initiation from RNA polymerase II promoter,protein localization,adrenal gland development,pituitary gland development,Sertoli cell differentiation,male sex determination,Leydig cell differentiation,negative regulation of intracellular steroid hormone receptor signaling pathway,gonad development,steroid hormone mediated signaling pathway,intracellular receptor signaling pathway,sex determination,cell differentiation,response to immobilization stress"," 46,XY SEX REVERSAL 2; SRXY2"]
["DCP2","DCP2 decapping enzyme homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:24452]","ENSG00000172795","ENSP00000425770",2,"DCP2[1],NUDIX[1]","family-785","DCP2",".",".","mRNA","mRNA","The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]",".",".",".",".",".",".","GO:0006402,GO:0003723,GO:0016896,GO:0050072,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0043928,GO:0071044,GO:0000184","mRNA catabolic process,RNA binding,exoribonuclease activity, producing 5'-phosphomonoesters,m7G(5')pppN diphosphatase activity,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0006402,GO:0003723,GO:0005515,GO:0016787,GO:0030145,GO:0016896,GO:0050072,GO:0005634,GO:0005829,GO:0000932,GO:0016442,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0043928,GO:0071044,GO:0000184","mRNA catabolic process,RNA binding,protein binding,hydrolase activity,manganese ion binding,exoribonuclease activity, producing 5'-phosphomonoesters,m7G(5')pppN diphosphatase activity,nucleus,cytosol,cytoplasmic mRNA processing body,RISC complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["TAF15","TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa [Source:HGNC Symbol;Acc:11547]","ENSG00000172660","ENSP00000466950",2,"zf-RanBP[1],RRM_1[1]","family-786","EWSR1,TAF15,FUS","EWSR1","TAF15[37,41],FUS[42,53]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0008270,GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0045893","zinc ion binding,nucleotide binding,RNA binding,protein binding,nucleic acid binding,DNA binding,nucleus,cytoplasm,positive regulation of transcription, DNA-dependent","."]
["EWSR1","Ewing sarcoma breakpoint region 1 [Source:HGNC Symbol;Acc:3508]","ENSG00000182944","ENSP00000330516",2,"zf-RanBP[1],RRM_6[1]","family-786","EWSR1,TAF15,FUS","EWSR1","TAF15[37,41],FUS[42,53]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0008270,GO:0003676,GO:0003723,GO:0005515,GO:0005516,GO:0042802,GO:0005634,GO:0005886,GO:0005737,GO:0006351,GO:0006355","nucleotide binding,zinc ion binding,nucleic acid binding,RNA binding,protein binding,calmodulin binding,identical protein binding,nucleus,plasma membrane,cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent"," HISTIOCYTOMA, ANGIOMATOID FIBROUS"]
["FUS","fused in sarcoma [Source:HGNC Symbol;Acc:4010]","ENSG00000089280","ENSP00000455282",2,"zf-RanBP[1],RRM_1[1]","family-786","EWSR1,TAF15,FUS","EWSR1","TAF15[37,41],FUS[42,53]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008380,GO:0000398","RNA binding,RNA splicing,mRNA splicing, via spliceosome","GO:0000166,GO:0008270,GO:0003676,GO:0003723,GO:0005515,GO:0003677,GO:0042802,GO:0005634,GO:0005737,GO:0005654,GO:0010467,GO:0008380,GO:0000398,GO:0008219","nucleotide binding,zinc ion binding,nucleic acid binding,RNA binding,protein binding,DNA binding,identical protein binding,nucleus,cytoplasm,nucleoplasm,gene expression,RNA splicing,mRNA splicing, via spliceosome,cell death"," AMYOTROPHIC LATERAL SCLEROSIS 6, WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA;"]
["EDC4","enhancer of mRNA decapping 4 [Source:HGNC Symbol;Acc:17157]","ENSG00000038358","ENSP00000351811",1,"WD40[1]","family-787","EDC4",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0043928","cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0000932,GO:0043231,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0043928","protein binding,nucleus,cytoplasm,cytosol,cytoplasmic mRNA processing body,intracellular membrane-bounded organelle,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["FBLL1","fibrillarin-like 1 [Source:HGNC Symbol;Acc:35458]","ENSG00000188573","ENSP00000473383",1,"Fibrillarin[1]","family-788","FBL,FBLL1","FBL","FBLL1[75,72]","snoRNA","putative snoRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0030529,GO:0006364,GO:0008033","RNA binding,ribonucleoprotein complex,rRNA processing,tRNA processing","GO:0003723,GO:0008168,GO:0005730,GO:0030529,GO:0006364,GO:0008033","RNA binding,methyltransferase activity,nucleolus,ribonucleoprotein complex,rRNA processing,tRNA processing","."]
["FBL","fibrillarin [Source:HGNC Symbol;Acc:3599]","ENSG00000105202","ENSP00000471867",1,"Fibrillarin[1]","family-788","FBL,FBLL1","FBL","FBLL1[75,72]","snoRNA","snoRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,".","GO:0003723,GO:0006364,GO:0008033,GO:0016429,GO:0031515,GO:0030488,GO:0031428,GO:0016074","RNA binding,rRNA processing,tRNA processing,tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,tRNA methylation,box C/D snoRNP complex,snoRNA metabolic process","GO:0003723,GO:0008168,GO:0006364,GO:0008033,GO:0016429,GO:0031515,GO:0030488,GO:0005515,GO:0005730,GO:0001652,GO:0015030,GO:0031428,GO:0016074","RNA binding,methyltransferase activity,rRNA processing,tRNA processing,tRNA (adenine-N1-)-methyltransferase activity,tRNA (m1A) methyltransferase complex,tRNA methylation,protein binding,nucleolus,granular component,Cajal body,box C/D snoRNP complex,snoRNA metabolic process","."]
["MRPS27","mitochondrial ribosomal protein S27 [Source:HGNC Symbol;Acc:14512]","ENSG00000113048","ENSP00000428120",1,"MRP-S27[1]","family-789","MRPS27",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",1,".","GO:0005840","ribosome","GO:0005739,GO:0005840,GO:0005515","mitochondrion,ribosome,protein binding","."]
["ALKBH1","alkB, alkylation repair homolog 1 (E. coli) [Source:HGNC Symbol;Acc:17911]","ENSG00000100601","ENSP00000216489",1,"2OG-FeII_Oxy_2[1]","family-79","ALKBH1",".",".","mRNA","putative mRNA/tRNA","15469826 ,18603530",".",".",".",".",".",".","GO:0042245","RNA repair","GO:0005515,GO:0070579,GO:0042056,GO:0003906,GO:0008198,GO:0005739,GO:0005719,GO:0010468,GO:0030154,GO:0050918,GO:0001890,GO:0001764,GO:0055114,GO:0006281,GO:0001701,GO:0048589,GO:0043524,GO:0042245,GO:0031175,GO:0080111,GO:0070989,GO:0006307","protein binding,methylcytosine dioxygenase activity,chemoattractant activity,DNA-(apurinic or apyrimidinic site) lyase activity,ferrous iron binding,mitochondrion,nuclear euchromatin,regulation of gene expression,cell differentiation,positive chemotaxis,placenta development,neuron migration,oxidation-reduction process,DNA repair,in utero embryonic development,developmental growth,negative regulation of neuron apoptotic process,RNA repair,neuron projection development,DNA demethylation,oxidative demethylation,DNA dealkylation involved in DNA repair","."]
["ZCCHC17","zinc finger, CCHC domain containing 17 [Source:HGNC Symbol;Acc:30246]","ENSG00000121766","ENSP00000444742",1,"S1[1]","family-790","ZCCHC17",".",".","unknown","unknown","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0022625","RNA binding,cytosolic large ribosomal subunit","GO:0003723,GO:0008270,GO:0003676,GO:0005515,GO:0005730,GO:0022625","RNA binding,zinc ion binding,nucleic acid binding,protein binding,nucleolus,cytosolic large ribosomal subunit","."]
["MRPL49","mitochondrial ribosomal protein L49 [Source:HGNC Symbol;Acc:1176]","ENSG00000149792","ENSP00000279242",1,"Img2[1]","family-791","MRPL49",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005761","structural constituent of ribosome,ribosome,translation,mitochondrial ribosome","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005515,GO:0005739,GO:0005761","structural constituent of ribosome,intracellular,ribosome,translation,protein binding,mitochondrion,mitochondrial ribosome","."]
["RPL18","ribosomal protein L18 [Source:HGNC Symbol;Acc:10310]","ENSG00000063177","ENSP00000447001",1,"Ribosomal_L18e[1]","family-792","RPL18",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS4X","ribosomal protein S4, X-linked [Source:HGNC Symbol;Acc:10424]","ENSG00000198034","ENSP00000362744",4,"KOW[1],Ribosomal_S4e[1],RS4NT[1],S4[1]","family-793","RPS4X,RPS4Y2,RPS4Y1","RPS4X","RPS4Y2[92,92],RPS4Y1[93,93]","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0019843,GO:0022627,GO:0030529,GO:0015935,GO:0016070,GO:0016071,GO:0045727,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,translation,rRNA binding,cytosolic small ribosomal subunit,ribonucleoprotein complex,small ribosomal subunit,RNA metabolic process,mRNA metabolic process,positive regulation of translation,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0019843,GO:0005829,GO:0005622,GO:0022627,GO:0030529,GO:0015935,GO:0005844,GO:0007275,GO:0008284,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0045727,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,ribosome,translation,rRNA binding,cytosol,intracellular,cytosolic small ribosomal subunit,ribonucleoprotein complex,small ribosomal subunit,polysome,multicellular organismal development,positive regulation of cell proliferation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,positive regulation of translation,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS4Y1","ribosomal protein S4, Y-linked 1 [Source:HGNC Symbol;Acc:10425]","ENSG00000129824","ENSP00000250784",4,"KOW[1],Ribosomal_S4e[1],RS4NT[1],S4[1]","family-793","RPS4X,RPS4Y2,RPS4Y1","RPS4X","RPS4Y2[92,92],RPS4Y1[93,93]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0006412,GO:0019843,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,translation,rRNA binding,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0019843,GO:0005829,GO:0022627,GO:0005844,GO:0007275,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,intracellular,ribosome,translation,rRNA binding,cytosol,cytosolic small ribosomal subunit,polysome,multicellular organismal development,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS4Y2","ribosomal protein S4, Y-linked 2 [Source:HGNC Symbol;Acc:18501]","ENSG00000157828","ENSP00000288666",3,"KOW[1],Ribosomal_S4e[1],RS4NT[1]","family-793","RPS4X,RPS4Y2,RPS4Y1","RPS4X","RPS4Y2[92,92],RPS4Y1[93,93]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0019843,GO:0005840,GO:0006412","RNA binding,structural constituent of ribosome,rRNA binding,ribosome,translation","GO:0003723,GO:0003735,GO:0019843,GO:0005622,GO:0005840,GO:0006412","RNA binding,structural constituent of ribosome,rRNA binding,intracellular,ribosome,translation","."]
["NOP14","NOP14 nucleolar protein [Source:HGNC Symbol;Acc:16821]","ENSG00000087269","ENSP00000405068",1,"Nop14[1]","family-794","NOP14",".",".","rRNA","rRNA","NOP14 plays a role in the processing of the pre-18S rRNA and small ribosomal subunit assembly (Liu and Thiele, 2001 [PubMed 11694595]).[supplied by OMIM, Jun 2009]","RNAbinding","RNAbinding",1,1,".",".","GO:0030515,GO:0030686,GO:0006364,GO:0000447,GO:0000472,GO:0000480,GO:0042274,GO:0000462","snoRNA binding,90S preribosome,rRNA processing,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal small subunit biogenesis,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0030515,GO:0005739,GO:0005730,GO:0032040,GO:0030686,GO:0030692,GO:0006364,GO:0000447,GO:0000472,GO:0000480,GO:0042274,GO:0000462","snoRNA binding,mitochondrion,nucleolus,small-subunit processome,90S preribosome,Noc4p-Nop14p complex,rRNA processing,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),ribosomal small subunit biogenesis,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["KRR1","KRR1, small subunit (SSU) processome component, homolog (yeast) [Source:HGNC Symbol;Acc:5176]","ENSG00000111615","ENSP00000411740",1,"KH_1[1]","family-795","KRR1",".",".","snoRNA","snoRNA/rRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0030529,GO:0006364","RNA binding,ribonucleoprotein complex,rRNA processing","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005730,GO:0030529,GO:0006364","RNA binding,protein binding,nucleus,cytoplasm,nucleolus,ribonucleoprotein complex,rRNA processing","."]
["NCL","nucleolin [Source:HGNC Symbol;Acc:7667]","ENSG00000115053","ENSP00000318195",4,"RRM_1[4]","family-796","NCL",".",".","snoRNA","snoRNA/rRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0005730,GO:0005654,GO:0005488,GO:0000166,GO:0003676,GO:0005515,GO:0003723,GO:0042802,GO:0008022,GO:0042162,GO:0005634,GO:0005938,GO:0030529,GO:0001525","nucleolus,nucleoplasm,binding,nucleotide binding,nucleic acid binding,protein binding,RNA binding,identical protein binding,protein C-terminus binding,telomeric DNA binding,nucleus,cell cortex,ribonucleoprotein complex,angiogenesis","."]
["PRPF18","PRP18 pre-mRNA processing factor 18 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17351]","ENSG00000165630","ENSP00000367835",2,"PRP4[1],Prp18[1]","family-797","PRPF18",".",".","mRNA","mRNA","Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0008380,GO:0005681,GO:0006397","RNA splicing,spliceosomal complex,mRNA processing","GO:0008380,GO:0005681,GO:0019870,GO:0005634,GO:0016607,GO:0006397","RNA splicing,spliceosomal complex,potassium channel inhibitor activity,nucleus,nuclear speck,mRNA processing","."]
["C1D","C1D nuclear receptor corepressor [Source:HGNC Symbol;Acc:29911]","ENSG00000197223","ENSP00000386468",1,"Sas10_Utp3[1]","family-798","C1D",".",".","rRNA","rRNA",17412707,".",".",".",".",".",".","GO:0003723,GO:0000176,GO:0000460","RNA binding,nuclear exosome (RNase complex),maturation of 5.8S rRNA","GO:0003723,GO:0003714,GO:0005515,GO:0003677,GO:0016922,GO:0005634,GO:0005739,GO:0005730,GO:0017053,GO:0000176,GO:0006351,GO:0006915,GO:0045892,GO:0000460","RNA binding,transcription corepressor activity,protein binding,DNA binding,ligand-dependent nuclear receptor binding,nucleus,mitochondrion,nucleolus,transcriptional repressor complex,nuclear exosome (RNase complex),transcription, DNA-templated,apoptotic process,negative regulation of transcription, DNA-dependent,maturation of 5.8S rRNA","."]
["ADAT3","adenosine deaminase, tRNA-specific 3 [Source:HGNC Symbol;Acc:25151]","ENSG00000213638","ENSP00000473571",1,"dCMP_cyt_deam_1[1]","family-799","ADAT3",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0008270,GO:0003824,GO:0016787,GO:0008033","zinc ion binding,catalytic activity,hydrolase activity,tRNA processing"," MENTAL RETARDATION, AUTOSOMAL RECESSIVE 36; MRT36"]
["UTP20","UTP20, small subunit (SSU) processome component, homolog (yeast) [Source:HGNC Symbol;Acc:17897]","ENSG00000120800","ENSP00000261637",1,"DRIM[1]","family-8","UTP20",".",".","snoRNA","snoRNA/rRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0030688,GO:0030686,GO:0006364,GO:0000447,GO:0000472,GO:0000480","preribosome, small subunit precursor,90S preribosome,rRNA processing,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","GO:0005488,GO:0005515,GO:0005737,GO:0005730,GO:0005654,GO:0032040,GO:0030688,GO:0030686,GO:0008285,GO:0006364,GO:0000447,GO:0000472,GO:0000480","binding,protein binding,cytoplasm,nucleolus,nucleoplasm,small-subunit processome,preribosome, small subunit precursor,90S preribosome,negative regulation of cell proliferation,rRNA processing,endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA),endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","."]
["SNIP1","Smad nuclear interacting protein 1 [Source:HGNC Symbol;Acc:30587]","ENSG00000163877","ENSP00000296215",1,"FHA[1]","family-80","SNIP1",".",".","ncRNA","miRNA/mRNA","This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED). [provided by RefSeq, Mar 2012]",".","RNArelated",".",1,".",".","GO:0035196","production of miRNAs involved in gene silencing by miRNA","GO:0005515,GO:0005634,GO:0005737,GO:0006355,GO:0007249,GO:0035196","protein binding,nucleus,cytoplasm,regulation of transcription, DNA-dependent,I-kappaB kinase/NF-kappaB signaling,production of miRNAs involved in gene silencing by miRNA"," PSYCHOMOTOR RETARDATION, EPILEPSY, AND CRANIOFACIAL DYSMORPHISM; "]
["GUF1","GUF1 GTPase homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25799]","ENSG00000151806","ENSP00000281543",5,"EFG_C[1],GTP_EFTU_D2[1],LepA_C[1],EFG_II[1],GTP_EFTU[1]","family-800","GUF1",".",".","mRNA","putative mRNA",18442968,".",".",".",".",".",".","GO:0006412","translation","GO:0005525,GO:0003924,GO:0005739,GO:0005743,GO:0007264,GO:0006412","GTP binding,GTPase activity,mitochondrion,mitochondrial inner membrane,small GTPase mediated signal transduction,translation","."]
["GCFC2","GC-rich sequence DNA-binding factor 2 [Source:HGNC Symbol;Acc:1317]","ENSG00000005436","ENSP00000318690",1,"GCFC[1]","family-801","GCFC2,PAXBP1","GCFC2","PAXBP1[34,29]","mRNA","putative mRNA",24304693,".",".",".",".",".",".",".",".","GO:0003700,GO:0003677,GO:0005634,GO:0006355,GO:0006351,GO:0045892","sequence-specific DNA binding transcription factor activity,DNA binding,nucleus,regulation of transcription, DNA-dependent,transcription, DNA-templated,negative regulation of transcription, DNA-dependent","."]
["UTP6","UTP6, small subunit (SSU) processome component, homolog (yeast) [Source:HGNC Symbol;Acc:18279]","ENSG00000108651","ENSP00000261708",1,"U3_assoc_6[1]","family-802","UTP6",".",".","snoRNA","snoRNA/rRNA","established RBP ",".",".",".",".",1,".","GO:0006364,GO:0006396","rRNA processing,RNA processing","GO:0005622,GO:0005730,GO:0006364,GO:0006396","intracellular,nucleolus,rRNA processing,RNA processing","."]
["SRSF1","serine/arginine-rich splicing factor 1 [Source:HGNC Symbol;Acc:10780]","ENSG00000136450","ENSP00000258962",2,"RRM_1[2]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0071013,GO:0006397,GO:0008380,GO:0000398,GO:0006376,GO:0006406,GO:0031124,GO:0000395","RNA binding,catalytic step 2 spliceosome,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing,mRNA 5'-splice site recognition","GO:0005515,GO:0000166,GO:0003723,GO:0003676,GO:0050733,GO:0005634,GO:0005737,GO:0005654,GO:0016607,GO:0035145,GO:0071013,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0001701,GO:0000398,GO:0006376,GO:0006406,GO:0060048,GO:0031124,GO:0006369,GO:0000395","protein binding,nucleotide binding,RNA binding,nucleic acid binding,RS domain binding,nucleus,cytoplasm,nucleoplasm,nuclear speck,exon-exon junction complex,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,in utero embryonic development,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,cardiac muscle contraction,mRNA 3'-end processing,termination of RNA polymerase II transcription,mRNA 5'-splice site recognition","."]
["SRSF3","serine/arginine-rich splicing factor 3 [Source:HGNC Symbol;Acc:10785]","ENSG00000112081","ENSP00000344762",1,"RRM_1[1]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008380,GO:0000398,GO:0006406,GO:0031124","RNA binding,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0043274,GO:0005654,GO:0016607,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0006369","nucleotide binding,nucleic acid binding,RNA binding,protein binding,phospholipase binding,nucleoplasm,nuclear speck,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["SRSF4","serine/arginine-rich splicing factor 4 [Source:HGNC Symbol;Acc:10786]","ENSG00000116350","ENSP00000362900",2,"RRM_1[2]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0048025,GO:0000375","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0000166,GO:0003676,GO:0003723,GO:0005634,GO:0005654,GO:0016607,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0048025,GO:0000375,GO:0006369","nucleotide binding,nucleic acid binding,RNA binding,nucleus,nucleoplasm,nuclear speck,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,termination of RNA polymerase II transcription","."]
["SRSF5","serine/arginine-rich splicing factor 5 [Source:HGNC Symbol;Acc:10787]","ENSG00000100650","ENSP00000451391",2,"RRM_1[2]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006376,GO:0006406,GO:0031124","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing","GO:0000166,GO:0003676,GO:0050733,GO:0005634,GO:0005737,GO:0005730,GO:0016607,GO:0009611,GO:0051726,GO:0003723,GO:0005515,GO:0005654,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006376,GO:0006406,GO:0031124,GO:0006369","nucleotide binding,nucleic acid binding,RS domain binding,nucleus,cytoplasm,nucleolus,nuclear speck,response to wounding,regulation of cell cycle,RNA binding,protein binding,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing,termination of RNA polymerase II transcription","."]
["SRSF6","serine/arginine-rich splicing factor 6 [Source:HGNC Symbol;Acc:10788]","ENSG00000124193","ENSP00000244020",2,"RRM_1[2]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008380,GO:0000381,GO:0000398,GO:0006376,GO:0006406,GO:0031124,GO:0048025","RNA binding,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005654,GO:0006366,GO:0010467,GO:0008380,GO:0000381,GO:0000398,GO:0006376,GO:0060548,GO:0006406,GO:0031124,GO:0048025,GO:0060501,GO:0006369","nucleotide binding,RNA binding,nucleic acid binding,nucleus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA splice site selection,negative regulation of cell death,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,positive regulation of epithelial cell proliferation involved in lung morphogenesis,termination of RNA polymerase II transcription","."]
["SRSF7","serine/arginine-rich splicing factor 7 [Source:HGNC Symbol;Acc:10789]","ENSG00000115875","ENSP00000386806",2,"RRM_1[1],zf-CCHC[1]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0048025","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0005634,GO:0005654,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006406,GO:0031124,GO:0048025,GO:0006369","nucleotide binding,RNA binding,protein binding,zinc ion binding,nucleic acid binding,nucleus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,termination of RNA polymerase II transcription","."]
["SRSF9","serine/arginine-rich splicing factor 9 [Source:HGNC Symbol;Acc:10791]","ENSG00000111786","ENSP00000229390",2,"RRM_1[2]","family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","SRSF1","SRSF7[33,35],SRSF3[27,41],SRSF9[63,71],SRSF4[46,23],SRSF5[45,41],SRSF6[44,32]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0000398,GO:0006376,GO:0006406,GO:0031124,GO:0048025","RNA binding,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome","GO:0003676,GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0005730,GO:0005654,GO:0006366,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0006376,GO:0006406,GO:0031124,GO:0048025,GO:0006369","nucleic acid binding,nucleotide binding,RNA binding,protein binding,nucleus,nucleolus,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,mRNA splice site selection,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,termination of RNA polymerase II transcription","."]
["USB1","U6 snRNA biogenesis 1 [Source:HGNC Symbol;Acc:25792]","ENSG00000103005","ENSP00000457322",1,"HVSL[1]","family-804","USB1",".",".","snRNA","snRNA",23022480,".",".",".",".",".",".","GO:0034477,GO:0000175,GO:0006397,GO:0008380","U6 snRNA 3'-end processing,3'-5'-exoribonuclease activity,mRNA processing,RNA splicing","GO:0004518,GO:0034477,GO:0000175,GO:0005634,GO:0006397,GO:0008380","nuclease activity,U6 snRNA 3'-end processing,3'-5'-exoribonuclease activity,nucleus,mRNA processing,RNA splicing"," POIKILODERMA WITH NEUTROPENIA; PN"]
["NOL6","nucleolar protein family 6 (RNA-associated) [Source:HGNC Symbol;Acc:19910]","ENSG00000165271","ENSP00000368783",1,"Nrap[1]","family-805","NOL6",".",".","rRNA","rRNA","The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]",".","RNAbinding",".",1,1,".","GO:0003723,GO:0006364","RNA binding,rRNA processing","GO:0003723,GO:0005730,GO:0000794,GO:0006364","RNA binding,nucleolus,condensed nuclear chromosome,rRNA processing","."]
["PPIE","peptidylprolyl isomerase E (cyclophilin E) [Source:HGNC Symbol;Acc:9258]","ENSG00000084072","ENSP00000361918",2,"RRM_1[1],Pro_isomerase[1]","family-806","PPIA,PPIF,PPIE,PPIAL4A,PPIAL4D,PPIAL4B,PPIAL4C,PPIAL4G","PPIA","PPIF[76,60],PPIE[63,33],PPIAL4A[85,86],PPIAL4D[84,84],PPIAL4B[85,86],PPIAL4C[85,86],PPIAL4G[84,85]","mRNA","mRNA","The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]",".","experimentally validated",".",1,1,1,"GO:0003723,GO:0071013,GO:0000398","RNA binding,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003755,GO:0016018,GO:0005634,GO:0071013,GO:0006457,GO:0006355,GO:0000398,GO:0045070,GO:0000413","nucleotide binding,RNA binding,protein binding,nucleic acid binding,peptidyl-prolyl cis-trans isomerase activity,cyclosporin A binding,nucleus,catalytic step 2 spliceosome,protein folding,regulation of transcription, DNA-dependent,mRNA splicing, via spliceosome,positive regulation of viral genome replication,protein peptidyl-prolyl isomerization","."]
["RRBP1","ribosome binding protein 1 homolog 180kDa (dog) [Source:HGNC Symbol;Acc:10448]","ENSG00000125844","ENSP00000367038",2,"Rib_recp_KP_reg[1],IncA[1]","family-807","KTN1,RRBP1","KTN1","RRBP1[17,24]","mRNA","putative mRNA",23318453,"candidate mRNA binder",".",".",1,".",".","GO:0005840,GO:0006412","ribosome,translation","GO:0005783,GO:0004872,GO:0030176,GO:0005840,GO:0015031,GO:0006412,GO:0007165","endoplasmic reticulum,receptor activity,integral to endoplasmic reticulum membrane,ribosome,protein transport,translation,signal transduction","."]
["SUZ12","SUZ12 polycomb repressive complex 2 subunit [Source:HGNC Symbol;Acc:17101]","ENSG00000178691","ENSP00000316578",1,"VEFS-Box[1]","family-808","SUZ12",".",".","ncRNA","lincRNA",20616235,".",".",".",".",".",".",".",".","GO:0005515,GO:0046872,GO:0035064,GO:0043565,GO:0003682,GO:0042054,GO:0005634,GO:0035098,GO:0001739,GO:0016571,GO:0000122,GO:0006351,GO:0008284,GO:0045596,GO:0016574","protein binding,metal ion binding,methylated histone residue binding,sequence-specific DNA binding,chromatin binding,histone methyltransferase activity,nucleus,ESC/E(Z) complex,sex chromatin,histone methylation,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,positive regulation of cell proliferation,negative regulation of cell differentiation,histone ubiquitination","."]
["TERT","telomerase reverse transcriptase [Source:HGNC Symbol;Acc:11730]","ENSG00000164362","ENSP00000309572",2,"Telomerase_RBD[1],RVT_1[1]","family-809","TERT",".",".","ncRNA","teloRNA","Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0003720,GO:0003721,GO:0070034,GO:0005697","RNA binding,telomerase activity,telomeric template RNA reverse transcriptase activity,telomeric RNA binding,telomerase holoenzyme complex","GO:0003723,GO:0005515,GO:0042803,GO:0046872,GO:0042162,GO:0003964,GO:0003720,GO:0003721,GO:0070034,GO:0005737,GO:0005730,GO:0016605,GO:0005654,GO:0000781,GO:0000783,GO:0005697,GO:0000723,GO:2001240,GO:0090399,GO:0007004,GO:0022616,GO:0032203,GO:0006278,GO:0005634","RNA binding,protein binding,protein homodimerization activity,metal ion binding,telomeric DNA binding,RNA-directed DNA polymerase activity,telomerase activity,telomeric template RNA reverse transcriptase activity,telomeric RNA binding,cytoplasm,nucleolus,PML body,nucleoplasm,chromosome, telomeric region,nuclear telomere cap complex,telomerase holoenzyme complex,telomere maintenance,negative regulation of extrinsic apoptotic signaling pathway in absence of ligand,replicative senescence,telomere maintenance via telomerase,DNA strand elongation,telomere formation via telomerase,RNA-dependent DNA replication,nucleus"," PULMONARY FIBROSIS, IDIOPATHIC; IPF"]
["MSL3","male-specific lethal 3 homolog (Drosophila) [Source:HGNC Symbol;Acc:7370]","ENSG00000005302","ENSP00000312244",2,"Tudor-knot[1],MRG[1]","family-81","MSL3",".",".","ncRNA","lincRNA",11014199,".",".",".",".",".",".",".",".","GO:0005634,GO:0003700,GO:0003677,GO:0035064,GO:0072487,GO:0007275,GO:0006366,GO:0043984","nucleus,sequence-specific DNA binding transcription factor activity,DNA binding,methylated histone residue binding,MSL complex,multicellular organismal development,transcription from RNA polymerase II promoter,histone H4-K16 acetylation","."]
["BICC1","bicaudal C homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:19351]","ENSG00000122870","ENSP00000362993",4,"SAM_1[1],KH_1[3]","family-810","BICC1",".",".","mRNA","mRNA","established RBP ",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0005737,GO:0007275,GO:0090090","RNA binding,protein binding,cytoplasm,multicellular organismal development,negative regulation of canonical Wnt signaling pathway"," RENAL DYSPLASIA, CYSTIC, SUSCEPTIBILITY TO; CYSRD"]
["MRPS16","mitochondrial ribosomal protein S16 [Source:HGNC Symbol;Acc:14048]","ENSG00000182180","ENSP00000362031",1,"Ribosomal_S16[1]","family-811","MRPS16",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005763","structural constituent of ribosome,ribosome,translation,mitochondrial small ribosomal subunit","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005515,GO:0005739,GO:0005763","structural constituent of ribosome,intracellular,ribosome,translation,protein binding,mitochondrion,mitochondrial small ribosomal subunit"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 2; COXPD2"]
["RBMX2","RNA binding motif protein, X-linked 2 [Source:HGNC Symbol;Acc:24282]","ENSG00000134597","ENSP00000339090",1,"RRM_1[1]","family-812","RBMX2",".",".","mRNA","putative mRNA","by homology",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0005515,GO:0003676","nucleotide binding,RNA binding,protein binding,nucleic acid binding","."]
["MRPL40","mitochondrial ribosomal protein L40 [Source:HGNC Symbol;Acc:14491]","ENSG00000185608","ENSP00000333401",1,"MRP-L28[1]","family-813","MRPL40",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0005761","mitochondrial ribosome","GO:0005739,GO:0005634,GO:0005761,GO:0009653","mitochondrion,nucleus,mitochondrial ribosome,anatomical structure morphogenesis","."]
["ISG20","interferon stimulated exonuclease gene 20kDa [Source:HGNC Symbol;Acc:6130]","ENSG00000172183","ENSP00000306565",1,"RNase_T[1]","family-814","AEN,ISG20L2,ISG20,REXO4","AEN","ISG20L2[38,35],ISG20[29,52],REXO4[25,19]","ncRNA","viral RNA",12594219,".",".",".",".",".",".","GO:0004527,GO:0000175,GO:0008859,GO:0006364,GO:0006401","exonuclease activity,3'-5'-exoribonuclease activity,exoribonuclease II activity,rRNA processing,RNA catabolic process","GO:0003676,GO:0004527,GO:0046872,GO:0000175,GO:0008310,GO:0008859,GO:0030619,GO:0030620,GO:0034511,GO:0005634,GO:0005737,GO:0005730,GO:0016605,GO:0005654,GO:0015030,GO:0008283,GO:0009615,GO:0045071,GO:0006364,GO:0019221,GO:0051607,GO:0006401,GO:0060337,GO:0000738","nucleic acid binding,exonuclease activity,metal ion binding,3'-5'-exoribonuclease activity,single-stranded DNA 3'-5' exodeoxyribonuclease activity,exoribonuclease II activity,U1 snRNA binding,U2 snRNA binding,U3 snoRNA binding,nucleus,cytoplasm,nucleolus,PML body,nucleoplasm,Cajal body,cell proliferation,response to virus,negative regulation of viral genome replication,rRNA processing,cytokine-mediated signaling pathway,defense response to virus,RNA catabolic process,type I interferon signaling pathway,DNA catabolic process, exonucleolytic","."]
["ISG20L2","interferon stimulated exonuclease gene 20kDa-like 2 [Source:HGNC Symbol;Acc:25745]","ENSG00000143319","ENSP00000323424",1,"RNase_T[1]","family-814","AEN,ISG20L2,ISG20,REXO4","AEN","ISG20L2[38,35],ISG20[29,52],REXO4[25,19]","rRNA","rRNA",18065403,".","RNArelated",".",1,1,".","GO:0004527,GO:0042254","exonuclease activity,ribosome biogenesis","GO:0005515,GO:0003676,GO:0004527,GO:0005634,GO:0043231,GO:0005730,GO:0042254","protein binding,nucleic acid binding,exonuclease activity,nucleus,intracellular membrane-bounded organelle,nucleolus,ribosome biogenesis","."]
["AEN","apoptosis enhancing nuclease [Source:HGNC Symbol;Acc:25722]","ENSG00000181026","ENSP00000453631",1,"RNase_T[1]","family-814","AEN,ISG20L2,ISG20,REXO4","AEN","ISG20L2[38,35],ISG20[29,52],REXO4[25,19]","diverse","putative diverse","by homology",".",".",".",".",1,".","GO:0004527","exonuclease activity","GO:0003676,GO:0004527,GO:0005634,GO:0005730,GO:0005654,GO:0010212,GO:0042771","nucleic acid binding,exonuclease activity,nucleus,nucleolus,nucleoplasm,response to ionizing radiation,intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","."]
["REXO4","REX4, RNA exonuclease 4 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:12820]","ENSG00000148300","ENSP00000361010",1,"RNase_T[1]","family-814","AEN,ISG20L2,ISG20,REXO4","AEN","ISG20L2[38,35],ISG20[29,52],REXO4[25,19]","rRNA","putative rRNA","Rex4p yeast homolog","nuclease","RNArelated",1,1,".",".","GO:0004527","exonuclease activity","GO:0003700,GO:0003676,GO:0004527,GO:0005634,GO:0005730,GO:0006355","sequence-specific DNA binding transcription factor activity,nucleic acid binding,exonuclease activity,nucleus,nucleolus,regulation of transcription, DNA-dependent","."]
["TGS1","trimethylguanosine synthase 1 [Source:HGNC Symbol;Acc:17843]","ENSG00000137574","ENSP00000260129",1,"Methyltransf_15[1]","family-815","TGS1",".",".","snRNA","snRNA/snoRNA",19386620,".",".",".",".",".",".","GO:0071164,GO:0030532,GO:0016070,GO:0001510,GO:0000387,GO:0034660,GO:0009452,GO:0022613,GO:0036261,GO:0071167","RNA trimethylguanosine synthase activity,small nuclear ribonucleoprotein complex,RNA metabolic process,RNA methylation,spliceosomal snRNP assembly,ncRNA metabolic process,7-methylguanosine RNA capping,ribonucleoprotein complex biogenesis,7-methylguanosine cap hypermethylation,ribonucleoprotein complex import into nucleus","GO:0005515,GO:0016740,GO:0008168,GO:0071164,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0030532,GO:0015030,GO:0006351,GO:0044255,GO:0044281,GO:0006355,GO:0010467,GO:0016070,GO:0001510,GO:0000387,GO:0034660,GO:0009452,GO:0022613,GO:0036261,GO:0071167","protein binding,transferase activity,methyltransferase activity,RNA trimethylguanosine synthase activity,nucleus,cytoplasm,cytosol,nucleoplasm,small nuclear ribonucleoprotein complex,Cajal body,transcription, DNA-templated,cellular lipid metabolic process,small molecule metabolic process,regulation of transcription, DNA-dependent,gene expression,RNA metabolic process,RNA methylation,spliceosomal snRNP assembly,ncRNA metabolic process,7-methylguanosine RNA capping,ribonucleoprotein complex biogenesis,7-methylguanosine cap hypermethylation,ribonucleoprotein complex import into nucleus","."]
["ZC3H4","zinc finger CCCH-type containing 4 [Source:HGNC Symbol;Acc:17808]","ENSG00000130749","ENSP00000469684",3,"zf-CCCH[3]","family-816","ZC3H4,ZC3H6,ZC3H8","ZC3H4","ZC3H6[30,33],ZC3H8[7,29]","unknown","unknown","by homology","RNAbinding","novel",1,1,1,1,".",".","GO:0046872","metal ion binding","."]
["ZC3H6","zinc finger CCCH-type containing 6 [Source:HGNC Symbol;Acc:24762]","ENSG00000188177","ENSP00000386764",2,"zf-CCCH[2]","family-816","ZC3H4,ZC3H6,ZC3H8","ZC3H4","ZC3H6[30,33],ZC3H8[7,29]","unknown","unknown","by homology",".",".",".",".",".",1,".",".","GO:0046872","metal ion binding","."]
["ZC3H8","zinc finger CCCH-type containing 8 [Source:HGNC Symbol;Acc:30941]","ENSG00000144161","ENSP00000386488",2,"zf-CCCH[2]","family-816","ZC3H4,ZC3H6,ZC3H8","ZC3H4","ZC3H6[30,33],ZC3H8[7,29]","unknown","unknown","by homology","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0003700,GO:0046872,GO:0043565,GO:0005634,GO:0006351,GO:0006915,GO:0045892,GO:0046677,GO:0043029,GO:0070245,GO:0033085","RNA binding,sequence-specific DNA binding transcription factor activity,metal ion binding,sequence-specific DNA binding,nucleus,transcription, DNA-templated,apoptotic process,negative regulation of transcription, DNA-dependent,response to antibiotic,T cell homeostasis,positive regulation of thymocyte apoptotic process,negative regulation of T cell differentiation in thymus","."]
["RPL27A","ribosomal protein L27a [Source:HGNC Symbol;Acc:10329]","ENSG00000166441","ENSP00000431565",1,"Ribosomal_L18e[1]","family-817","RPL27A",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005515,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,protein binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPS19","ribosomal protein S19 [Source:HGNC Symbol;Acc:10402]","ENSG00000105372","ENSP00000470972",1,"Ribosomal_S19e[1]","family-818","RPS19",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022627,GO:0000028,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274,GO:0000462,GO:0030490","structural constituent of ribosome,ribosome,translation,cytosolic small ribosomal subunit,ribosomal small subunit assembly,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),maturation of SSU-rRNA","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0005515,GO:0042803,GO:0019901,GO:0017134,GO:0005737,GO:0005829,GO:0005730,GO:0022627,GO:0051272,GO:0000028,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0030218,GO:0051262,GO:0007000,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0002548,GO:0000184,GO:0060266,GO:0006415,GO:0019083,GO:0042274,GO:0060265,GO:0000462,GO:0009991,GO:0030490","structural constituent of ribosome,intracellular,ribosome,translation,protein binding,protein homodimerization activity,protein kinase binding,fibroblast growth factor binding,cytoplasm,cytosol,nucleolus,cytosolic small ribosomal subunit,positive regulation of cellular component movement,ribosomal small subunit assembly,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,erythrocyte differentiation,protein tetramerization,nucleolus organization,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,monocyte chemotaxis,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,negative regulation of respiratory burst involved in inflammatory response,translational termination,viral transcription,ribosomal small subunit biogenesis,positive regulation of respiratory burst involved in inflammatory response,maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA),response to extracellular stimulus,maturation of SSU-rRNA"," DIAMOND-BLACKFAN ANEMIA 1; DBA1"]
["SYF2","SYF2 homolog, RNA splicing factor (S. cerevisiae) [Source:HGNC Symbol;Acc:19824]","ENSG00000117614","ENSP00000236273",1,"SYF2[1]","family-819","SYF2",".",".","mRNA","mRNA","established RBP ","candidate mRNA binder","RNArelated",1,1,1,".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005634,GO:0071013,GO:0001701,GO:0000398,GO:0007369,GO:0000075,GO:0048568","nucleus,catalytic step 2 spliceosome,in utero embryonic development,mRNA splicing, via spliceosome,gastrulation,cell cycle checkpoint,embryonic organ development","."]
["TFB1M","transcription factor B1, mitochondrial [Source:HGNC Symbol;Acc:17037]","ENSG00000029639","ENSP00000356134",1,"RrnaAD[1]","family-82","DIMT1,TFB1M","DIMT1","TFB1M[25,23]","rRNA","rRNA",17031457,".","RNArelated",".",1,".",".","GO:0003723,GO:0000179,GO:0008649,GO:0000154","RNA binding,rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,rRNA modification","GO:0003723,GO:0005515,GO:0003677,GO:0000179,GO:0008649,GO:0005739,GO:0042645,GO:0006351,GO:0006355,GO:0000154","RNA binding,protein binding,DNA binding,rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,mitochondrion,mitochondrial nucleoid,transcription, DNA-templated,regulation of transcription, DNA-dependent,rRNA modification","."]
["DIMT1","DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:30217]","ENSG00000086189","ENSP00000199320",1,"RrnaAD[1]","family-82","DIMT1,TFB1M","DIMT1","TFB1M[25,23]","rRNA","putative rRNA","DIM1 yeast homolog","RNAmod","RNAbinding",1,1,1,".","GO:0000179,GO:0008649,GO:0000154,GO:0003723,GO:0016433,GO:0052909,GO:0006364","rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,rRNA modification,RNA binding,rRNA (adenine) methyltransferase activity,18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity,rRNA processing","GO:0016740,GO:0008168,GO:0000179,GO:0008649,GO:0008152,GO:0000154,GO:0003723,GO:0016433,GO:0052909,GO:0005730,GO:0006364","transferase activity,methyltransferase activity,rRNA (adenine-N6,N6-)-dimethyltransferase activity,rRNA methyltransferase activity,metabolic process,rRNA modification,RNA binding,rRNA (adenine) methyltransferase activity,18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity,nucleolus,rRNA processing","."]
["TSEN34","tRNA splicing endonuclease 34 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:15506]","ENSG00000170892","ENSP00000379667",1,"tRNA_int_endo[1]","family-820","TSEN34",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0000213,GO:0000214,GO:0006397,GO:0006388,GO:0000379","tRNA-intron endonuclease activity,tRNA-intron endonuclease complex,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation,tRNA-type intron splice site recognition and cleavage","GO:0003676,GO:0000213,GO:0005730,GO:0000214,GO:0006397,GO:0006388,GO:0000379,GO:0005515","nucleic acid binding,tRNA-intron endonuclease activity,nucleolus,tRNA-intron endonuclease complex,mRNA processing,tRNA splicing, via endonucleolytic cleavage and ligation,tRNA-type intron splice site recognition and cleavage,protein binding"," PONTOCEREBELLAR HYPOPLASIA, TYPE 2C; PCH2C"]
["DCAF13","DDB1 and CUL4 associated factor 13 [Source:HGNC Symbol;Acc:24535]","ENSG00000164934","ENSP00000297579",5,"Sof1[1],WD40[4]","family-821","DCAF13",".",".","rRNA","putative rRNA","SOF1 yeast homolog","candidate mRNA binder","RNArelated",1,1,1,".","GO:0030529,GO:0006364","ribonucleoprotein complex,rRNA processing","GO:0005515,GO:0005730,GO:0030529,GO:0080008,GO:0016567,GO:0006364","protein binding,nucleolus,ribonucleoprotein complex,Cul4-RING ubiquitin ligase complex,protein ubiquitination,rRNA processing","."]
["RPL9","ribosomal protein L9 [Source:HGNC Symbol;Acc:10369]","ENSG00000163682","ENSP00000400467",2,"Ribosomal_L6[2]","family-822","RPL9",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0019843,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,rRNA binding,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0019843,GO:0005840,GO:0006412,GO:0005737,GO:0005730,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,rRNA binding,ribosome,translation,cytoplasm,nucleolus,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ARHGEF28","Rho guanine nucleotide exchange factor (GEF) 28 [Source:HGNC Symbol;Acc:30322] [Type: protein coding Ensembl/Havana merge]","ENSG00000214944","ENSP00000441913",3,"PH[1],RhoGEF[1],C1_1[1]","family-823","AKAP13,ARHGEF2,ARHGEF18,ARHGEF28","AKAP13","ARHGEF2[13,38],ARHGEF18[14,33],ARHGEF28[19,31]","mRNA","mRNA",19488899,".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0046872,GO:0005089,GO:0005886,GO:0005737,GO:0015630,GO:0030154,GO:0035023,GO:0035556,GO:0021955,GO:0060052,GO:0005515","RNA binding,metal ion binding,Rho guanyl-nucleotide exchange factor activity,plasma membrane,cytoplasm,microtubule cytoskeleton,cell differentiation,regulation of Rho protein signal transduction,intracellular signal transduction,central nervous system neuron axonogenesis,neurofilament cytoskeleton organization,protein binding","."]
["AC004381.6","Putative RNA exonuclease NEF-sp  [Source:UniProtKB/Swiss-Prot;Acc:Q96IC2]","ENSG00000005189","ENSP00000261377",3,"RRM_1[2],RNase_T[1]","family-824","AC004381.6",".",".","rRNA","rRNA/tRNA","by homology, Rex1p",".",".",".",".",".",1,"GO:0003723,GO:0004527","RNA binding,exonuclease activity","GO:0000166,GO:0003723,GO:0003676,GO:0004527,GO:0005730","nucleotide binding,RNA binding,nucleic acid binding,exonuclease activity,nucleolus","."]
["EIF4H","eukaryotic translation initiation factor 4H [Source:HGNC Symbol;Acc:12741]","ENSG00000263344","ENSP00000458302",1,"RRM_1[1]","family-825","EIF4B,EIF4H","EIF4B","EIF4H[13,33]","mRNA","mRNA",11418588,"translationfactor","RNAbinding",1,1,1,1,"GO:0003723,GO:0003743,GO:0008135,GO:0016281,GO:0006412,GO:0006446,GO:0006413","RNA binding,translation initiation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 4F complex,translation,regulation of translational initiation,translational initiation","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003743,GO:0008135,GO:0005829,GO:0048471,GO:0016281,GO:0006412,GO:0010467,GO:0048589,GO:0006446,GO:0044267,GO:0019953,GO:0019048,GO:0006413","nucleotide binding,RNA binding,protein binding,nucleic acid binding,translation initiation factor activity,translation factor activity, nucleic acid binding,cytosol,perinuclear region of cytoplasm,eukaryotic translation initiation factor 4F complex,translation,gene expression,developmental growth,regulation of translational initiation,cellular protein metabolic process,sexual reproduction,modulation by virus of host morphology or physiology,translational initiation","."]
["EIF4B","eukaryotic translation initiation factor 4B [Source:HGNC Symbol;Acc:3285]","ENSG00000063046","ENSP00000450324",1,"RRM_1[1]","family-825","EIF4B,EIF4H","EIF4B","EIF4H[13,33]","mRNA","mRNA",12885229,"translationfactor","experimentally validated",1,1,1,1,"GO:0003743,GO:0003723,GO:0016281,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006446,GO:0006413","translation initiation factor activity,RNA binding,eukaryotic translation initiation factor 4F complex,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translational initiation,translational initiation","GO:0000166,GO:0003676,GO:0003743,GO:0003723,GO:0005515,GO:0005829,GO:0016281,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0008286,GO:0006446,GO:0044267,GO:0006413","nucleotide binding,nucleic acid binding,translation initiation factor activity,RNA binding,protein binding,cytosol,eukaryotic translation initiation factor 4F complex,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,insulin receptor signaling pathway,regulation of translational initiation,cellular protein metabolic process,translational initiation","."]
["DDX54","DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 [Source:HGNC Symbol;Acc:20084]","ENSG00000123064","ENSP00000323858",3,"Helicase_C[1],DBP10CT[1],DEAD[1]","family-826","DDX54",".",".","rRNA","rRNA","yeast homolog DBP10","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0004004,GO:0016070,GO:0006396","RNA binding,ATP-dependent RNA helicase activity,RNA metabolic process,RNA processing","GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0003723,GO:0016818,GO:0005634,GO:0003714,GO:0030331,GO:0005102,GO:0004386,GO:0004004,GO:0005730,GO:0006351,GO:0006355,GO:0016070,GO:0006396,GO:0030520","ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,RNA binding,hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides,nucleus,transcription corepressor activity,estrogen receptor binding,receptor binding,helicase activity,ATP-dependent RNA helicase activity,nucleolus,transcription, DNA-templated,regulation of transcription, DNA-dependent,RNA metabolic process,RNA processing,intracellular estrogen receptor signaling pathway","."]
["MRPS36","mitochondrial ribosomal protein S36 [Source:HGNC Symbol;Acc:16631]","ENSG00000134056","ENSP00000256441",1,"DUF2638[1]","family-827","MRPS36",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005739,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrion,mitochondrial small ribosomal subunit,translation","."]
["PRPF40A","PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:16463]","ENSG00000196504","ENSP00000386458",7,"FF[5],WW[2]","family-828","PRPF40A,PRPF40B","PRPF40A","PRPF40B[55,57]","snRNA","putative snRNA /mRNA","U1 snRNP protein involved in splicing; contains multiple tetriatricopeptide repeats","candidate mRNA binder",".",".",1,".",".","GO:0006397,GO:0008380","mRNA processing,RNA splicing","GO:0005515,GO:0005634,GO:0070064,GO:0016363,GO:0016607,GO:0007010,GO:0051301,GO:0007049,GO:0006397,GO:0008380,GO:0008360,GO:0016477,GO:0032465","protein binding,nucleus,proline-rich region binding,nuclear matrix,nuclear speck,cytoskeleton organization,cell division,cell cycle,mRNA processing,RNA splicing,regulation of cell shape,cell migration,regulation of cytokinesis","."]
["PRPF40B","PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25031]","ENSG00000110844","ENSP00000448073",5,"FF[3],WW[2]","family-828","PRPF40A,PRPF40B","PRPF40A","PRPF40B[55,57]","snRNA","putative snRNA /mRNA","U1 snRNP protein involved in splicing; contains multiple tetriatricopeptide repeats",".",".",".",".",".",".","GO:0006397,GO:0008380","mRNA processing,RNA splicing","GO:0005515,GO:0016607,GO:0006397,GO:0008380","protein binding,nuclear speck,mRNA processing,RNA splicing","."]
["EIF3L","eukaryotic translation initiation factor 3 subunit L isoform 2  [Source:RefSeq peptide;Acc:NP_001229852]","ENSG00000100129","ENSP00000416892",1,"Paf67[1]","family-829","EIF3L",".",".","mRNA","mRNA",17322308,"translationfactor","novel",1,1,".",".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation","GO:0003743,GO:0005737,GO:0005852,GO:0005654,GO:0001650,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0005515,GO:0006413,GO:0005730","translation initiation factor activity,cytoplasm,eukaryotic translation initiation factor 3 complex,nucleoplasm,fibrillar center,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,protein binding,translational initiation,nucleolus","."]
["NOL8","nucleolar protein 8 [Source:HGNC Symbol;Acc:23387]","ENSG00000198000","ENSP00000401177",1,"RRM_6[1]","family-83","NOL8",".",".","rRNA","rRNA",16963496,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006364","RNA binding,rRNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005730,GO:0006260,GO:0006364,GO:0030307,GO:0003676","nucleotide binding,RNA binding,protein binding,nucleus,cytoplasm,nucleolus,DNA replication,rRNA processing,positive regulation of cell growth,nucleic acid binding","."]
["MTO1","mitochondrial translation optimization 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:19261]","ENSG00000135297","ENSP00000359323",2,"GIDA_assoc_3[1],GIDA[1]","family-830","MTO1",".",".","tRNA","tRNA","This gene encodes a mitochondrial protein thought to be involved in mitochondrial tRNA modification. The encoded protein may also play a role in the expression of the non-syndromic and aminoglycoside-induced deafness phenotypes associated with a specific mutation in the mitochondrial 12S rRNA gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","translationfactor",".",".",1,".",".","GO:0008033,GO:0070899,GO:0002098","tRNA processing,mitochondrial tRNA wobble uridine modification,tRNA wobble uridine modification","GO:0050660,GO:0008033,GO:0016491,GO:0055114,GO:0005739,GO:0070899,GO:0002098","flavin adenine dinucleotide binding,tRNA processing,oxidoreductase activity,oxidation-reduction process,mitochondrion,mitochondrial tRNA wobble uridine modification,tRNA wobble uridine modification"," COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 10; COXPD10"]
["PSMA1","proteasome (prosome, macropain) subunit, alpha type, 1 [Source:HGNC Symbol;Acc:9530]","ENSG00000129084","ENSP00000414359",2,"Proteasome[1],Proteasome_A_N[1]","family-831","PSMA1,PSMA1,PSMA1","PSMA1","PSMA1[45,74],PSMA1[74,45]","unknown","unknown",7681138,".",".",".",".",".",".","GO:0003723,GO:0016070,GO:0016071","RNA binding,RNA metabolic process,mRNA metabolic process","GO:0004298,GO:0004175,GO:0005634,GO:0005737,GO:0005839,GO:0019773,GO:0006511,GO:0051603,GO:0003723,GO:0005515,GO:0001530,GO:0005829,GO:0005654,GO:0005813,GO:0000502,GO:0005844,GO:0006915,GO:0042981,GO:0043066,GO:0044281,GO:0000209,GO:0002474,GO:0000278,GO:0016032,GO:0002479,GO:0006521,GO:0006977,GO:0010467,GO:0016070,GO:0016071,GO:0031145,GO:0034641,GO:0042590,GO:0051437,GO:0051439,GO:0000082,GO:0002862,GO:0051436","threonine-type endopeptidase activity,endopeptidase activity,nucleus,cytoplasm,proteasome core complex,proteasome core complex, alpha-subunit complex,ubiquitin-dependent protein catabolic process,proteolysis involved in cellular protein catabolic process,RNA binding,protein binding,lipopolysaccharide binding,cytosol,nucleoplasm,centrosome,proteasome complex,polysome,apoptotic process,regulation of apoptotic process,negative regulation of apoptotic process,small molecule metabolic process,protein polyubiquitination,antigen processing and presentation of peptide antigen via MHC class I,mitotic cell cycle,viral process,antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent,regulation of cellular amino acid metabolic process,DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest,gene expression,RNA metabolic process,mRNA metabolic process,anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process,cellular nitrogen compound metabolic process,antigen processing and presentation of exogenous peptide antigen via MHC class I,positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle,G1/S transition of mitotic cell cycle,negative regulation of inflammatory response to antigenic stimulus,negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle","."]
["HTATSF1","HIV-1 Tat specific factor 1 [Source:HGNC Symbol;Acc:5276]","ENSG00000102241","ENSP00000218364",2,"RRM_5[1],RRM_1[1]","family-832","HTATSF1",".",".","mRNA","putative mRNA","The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]",".","RNAbinding",".",1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0006351,GO:0006357,GO:0019079,GO:0032784","nucleotide binding,RNA binding,nucleic acid binding,nucleus,transcription, DNA-templated,regulation of transcription from RNA polymerase II promoter,viral genome replication,regulation of DNA-dependent transcription, elongation","."]
["FTSJ1","FtsJ RNA methyltransferase homolog 1 (E. coli) [Source:HGNC Symbol;Acc:13254]","ENSG00000269875","ENSP00000471096",1,"FtsJ[1]","family-833","FTSJ1",".",".","tRNA","putative tRNA","TRM7 yeast homolog",".",".",".",".",".",".","GO:0001510","RNA methylation","GO:0008168,GO:0001510,GO:0032259,GO:0008175,GO:0005737","methyltransferase activity,RNA methylation,methylation,tRNA methyltransferase activity,cytoplasm"," MENTAL RETARDATION, X-LINKED 9; MRX9"]
["LAS1L","LAS1-like (S. cerevisiae) [Source:HGNC Symbol;Acc:25726]","ENSG00000001497","ENSP00000308649",1,"Las1[1]","family-834","LAS1L",".",".","rRNA","rRNA",22190735,"candidate mRNA binder","novel",1,1,1,".","GO:0006364","rRNA processing","GO:0005634,GO:0005737,GO:0071339,GO:0006364","nucleus,cytoplasm,MLL1 complex,rRNA processing","."]
["POP1","processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:30129]","ENSG00000104356","ENSP00000385787",2,"POPLD[1],POP1[1]","family-835","POP1",".",".","ncRNA","MRP RNA","This gene encodes the protein subunit of two different small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is a ribonuclease that localizes to the nucleus and functions in pre-RNA processing. This protein is also an autoantigen in patients suffering from connective tissue diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]",".","RNArelated",".",1,".",".","GO:0004526,GO:0000171,GO:0000172,GO:0005655,GO:0006396,GO:0001682,GO:0016078","ribonuclease P activity,ribonuclease MRP activity,ribonuclease MRP complex,nucleolar ribonuclease P complex,RNA processing,tRNA 5'-leader removal,tRNA catabolic process","GO:0005515,GO:0004526,GO:0000171,GO:0000172,GO:0005655,GO:0006396,GO:0001682,GO:0016078","protein binding,ribonuclease P activity,ribonuclease MRP activity,ribonuclease MRP complex,nucleolar ribonuclease P complex,RNA processing,tRNA 5'-leader removal,tRNA catabolic process","."]
["DZIP3","DAZ interacting protein 3, zinc finger [Source:HGNC Symbol;Acc:30938]","ENSG00000198919","ENSP00000355028",1,"zf-RING_2[1]","family-836","DZIP3",".",".","mRNA","mRNA",12538761,".","RNAbinding",".",1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0008270,GO:0046872,GO:0004842,GO:0019902,GO:0031593,GO:0005737,GO:0000209","RNA binding,protein binding,zinc ion binding,metal ion binding,ubiquitin-protein ligase activity,phosphatase binding,polyubiquitin binding,cytoplasm,protein polyubiquitination","."]
["DGCR14","DiGeorge syndrome critical region gene 14 [Source:HGNC Symbol;Acc:16817] ","ENSG00000100056","ENSP00000252137",1,"Es2[1]","family-837","DGCR14",".",".","mRNA","mRNA","11991638, The encoded protein may be a component of C complex spliceosomes, and the orthologous protein in the mouse localizes to the nucleus. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0005634,GO:0071013,GO:0007399,GO:0000398","protein binding,nucleus,catalytic step 2 spliceosome,nervous system development,mRNA splicing, via spliceosome","."]
["CDK9","cyclin-dependent kinase 9 [Source:HGNC Symbol;Acc:1780]","ENSG00000136807","ENSP00000362361",1,"Pkinase[1]","family-838","CDK10,CDK11B,CDK11A,CDK13,CDK9,CDK12","CDK10","CDK11B[51,23],CDK11A[51,23],CDK13[38,9],CDK9[34,33],CDK12[39,9]","ncRNA","7SK","The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0017069","snRNA binding","GO:0005515,GO:0005524,GO:0003677,GO:0004672,GO:0003682,GO:0004713,GO:0044212,GO:0004693,GO:0016772,GO:0017069,GO:0008353,GO:0005634,GO:0005737,GO:0043231,GO:0016605,GO:0005654,GO:0008023,GO:0008024,GO:0006351,GO:0008283,GO:0045944,GO:0006366,GO:0006281,GO:0016032,GO:0010467,GO:0006468,GO:0006367,GO:0071157,GO:0007179,GO:0071345,GO:0006368,GO:0050434,GO:0006282,GO:0031056,GO:0043111","protein binding,ATP binding,DNA binding,protein kinase activity,chromatin binding,protein tyrosine kinase activity,transcription regulatory region DNA binding,cyclin-dependent protein serine/threonine kinase activity,transferase activity, transferring phosphorus-containing groups,snRNA binding,RNA polymerase II carboxy-terminal domain kinase activity,nucleus,cytoplasm,intracellular membrane-bounded organelle,PML body,nucleoplasm,transcription elongation factor complex,positive transcription elongation factor complex b,transcription, DNA-templated,cell proliferation,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,DNA repair,viral process,gene expression,protein phosphorylation,transcription initiation from RNA polymerase II promoter,negative regulation of cell cycle arrest,transforming growth factor beta receptor signaling pathway,cellular response to cytokine stimulus,transcription elongation from RNA polymerase II promoter,positive regulation of viral transcription,regulation of DNA repair,regulation of histone modification,replication fork arrest","."]
["PAN3","PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29991]","ENSG00000152520","ENSP00000370345",2,"Pkinase[1],zf-CCCH[1]","family-839","PAN3",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",1,"GO:0004535,GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0010606,GO:0000290,GO:0000184","poly(A)-specific ribonuclease activity,cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of cytoplasmic mRNA processing body assembly,deadenylation-dependent decapping of nuclear-transcribed mRNA,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0005524,GO:0046872,GO:0004672,GO:0004535,GO:0016772,GO:0005829,GO:0000932,GO:0005813,GO:0031251,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0010606,GO:0006468,GO:0006605,GO:0000290,GO:0000184","protein binding,ATP binding,metal ion binding,protein kinase activity,poly(A)-specific ribonuclease activity,transferase activity, transferring phosphorus-containing groups,cytosol,cytoplasmic mRNA processing body,centrosome,PAN complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,positive regulation of cytoplasmic mRNA processing body assembly,protein phosphorylation,protein targeting,deadenylation-dependent decapping of nuclear-transcribed mRNA,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["RPL29","ribosomal protein L29 [Source:HGNC Symbol;Acc:10331]","ENSG00000162244","ENSP00000420673",1,"Ribosomal_L29e[1]","family-84","RPL29",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0008201,GO:0005829,GO:0022625,GO:0007566,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,heparin binding,cytosol,cytosolic large ribosomal subunit,embryo implantation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["DCPS","decapping enzyme, scavenger [Source:HGNC Symbol;Acc:29812]","ENSG00000110063","ENSP00000263579",2,"DcpS[1],DcpS_C[1]","family-840","DCPS",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0000340,GO:0050072,GO:0016070,GO:0016071,GO:0000288,GO:0045292,GO:0000290,GO:0043928","RNA 7-methylguanosine cap binding,m7G(5')pppN diphosphatase activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA cis splicing, via spliceosome,deadenylation-dependent decapping of nuclear-transcribed mRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0005515,GO:0003824,GO:0016787,GO:0000340,GO:0050072,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0045292,GO:0000290,GO:0043069,GO:0043928,GO:0036245","protein binding,catalytic activity,hydrolase activity,RNA 7-methylguanosine cap binding,m7G(5')pppN diphosphatase activity,nucleus,cytoplasm,mitochondrion,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA cis splicing, via spliceosome,deadenylation-dependent decapping of nuclear-transcribed mRNA,negative regulation of programmed cell death,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,cellular response to menadione","."]
["MRP63","mitochondrial ribosomal protein 63 [Source:HGNC Symbol;Acc:14514]","ENSG00000173141","ENSP00000310726",1,"MRP-63[1]","family-841","MRP63",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrial ribosome,translation","GO:0003735,GO:0005739,GO:0005761,GO:0006412","structural constituent of ribosome,mitochondrion,mitochondrial ribosome,translation","."]
["MRPL27","mitochondrial ribosomal protein L27 [Source:HGNC Symbol;Acc:14483]","ENSG00000108826","ENSP00000388915",1,"Ribosomal_L27[1]","family-842","MRPL27",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal","RNArelated",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0005762","structural constituent of ribosome,ribosome,translation,mitochondrial large ribosomal subunit","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0006412,GO:0005762","structural constituent of ribosome,mitochondrion,intracellular,ribosome,translation,mitochondrial large ribosomal subunit","."]
["POLR2H","polymerase (RNA) II (DNA directed) polypeptide H [Source:HGNC Symbol;Acc:9195]","ENSG00000163882","ENSP00000392913",1,"RNA_pol_Rpb8[1]","family-843","POLR2H",".",".","mRNA","mRNA","Pol II complex",".",".",".",".",".",".","GO:0008380,GO:0000398,GO:0006370","RNA splicing,mRNA splicing, via spliceosome,7-methylguanosine mRNA capping","GO:0008270,GO:0003677,GO:0001055,GO:0003899,GO:0001056,GO:0001054,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0005665,GO:0005736,GO:0005666,GO:0006351,GO:0045087,GO:0006366,GO:0006289,GO:0006281,GO:0016032,GO:0010467,GO:0006383,GO:0008380,GO:0000398,GO:0006367,GO:0006368,GO:0006360,GO:0006370,GO:0006361,GO:0032481,GO:0006283,GO:0050434,GO:0006385,GO:0006386,GO:0006362,GO:0006363","zinc ion binding,DNA binding,RNA polymerase II activity,DNA-directed RNA polymerase activity,RNA polymerase III activity,RNA polymerase I activity,nucleus,cytoplasm,cytosol,nucleoplasm,DNA-directed RNA polymerase II, core complex,DNA-directed RNA polymerase I complex,DNA-directed RNA polymerase III complex,transcription, DNA-templated,innate immune response,transcription from RNA polymerase II promoter,nucleotide-excision repair,DNA repair,viral process,gene expression,transcription from RNA polymerase III promoter,RNA splicing,mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,transcription from RNA polymerase I promoter,7-methylguanosine mRNA capping,transcription initiation from RNA polymerase I promoter,positive regulation of type I interferon production,transcription-coupled nucleotide-excision repair,positive regulation of viral transcription,transcription elongation from RNA polymerase III promoter,termination of RNA polymerase III transcription,transcription elongation from RNA polymerase I promoter,termination of RNA polymerase I transcription","."]
["ZNF239","zinc finger protein 239 [Source:HGNC Symbol;Acc:13031]","ENSG00000196793","ENSP00000307774",9,"zf-H2C2_2[9]","family-844","ZNF239,ZNF664","ZNF239","ZNF664[34,61]","unknown","unknown","MOK2 proteins are DNA- and RNA-binding proteins that are mainly associated with nuclear RNP components, including the nucleoli and extranucleolar structures (Arranz et al., 1997 [PubMed 9121460]).[supplied by OMIM, Mar 2008]",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0003723,GO:0046872,GO:0003677,GO:0005634,GO:0006351,GO:0006355","RNA binding,metal ion binding,DNA binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["XRN1","5'-3' exoribonuclease 1 [Source:HGNC Symbol;Acc:30654]","ENSG00000114127","ENSP00000418404",1,"XRN_N[1]","family-845","XRN1",".",".","diverse","diverse","established RBP ","nuclease","RNAbinding",1,1,".",".","GO:0004527,GO:0000932,GO:0003723,GO:0008409,GO:0016070,GO:0016071,GO:0000288,GO:0016075,GO:0043928,GO:0071044,GO:0071028,GO:0000956","exonuclease activity,cytoplasmic mRNA processing body,RNA binding,5'-3' exonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear mRNA surveillance,nuclear-transcribed mRNA catabolic process","GO:0003676,GO:0004527,GO:0005622,GO:0000932,GO:0003723,GO:0005515,GO:0003677,GO:0008409,GO:0005886,GO:0005737,GO:0005829,GO:0005794,GO:0045111,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0016075,GO:0043928,GO:0071044,GO:0071028,GO:0000956","nucleic acid binding,exonuclease activity,intracellular,cytoplasmic mRNA processing body,RNA binding,protein binding,DNA binding,5'-3' exonuclease activity,plasma membrane,cytoplasm,cytosol,Golgi apparatus,intermediate filament cytoskeleton,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,rRNA catabolic process,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process,nuclear mRNA surveillance,nuclear-transcribed mRNA catabolic process","."]
["ZFR","zinc finger RNA binding protein [Source:HGNC Symbol;Acc:17277]","ENSG00000056097","ENSP00000265069",4,"zf-met[3],DZF[1]","family-846","ZFR,ZFR2","ZFR","ZFR2[42,48]","unknown","unknown","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0005694,GO:0007275","RNA binding,protein binding,zinc ion binding,nucleic acid binding,DNA binding,nucleus,cytoplasm,chromosome,multicellular organismal development","."]
["ZFR2","zinc finger RNA binding protein 2 [Source:HGNC Symbol;Acc:29189]","ENSG00000105278","ENSP00000262961",4,"zf-C2H2_jaz[1],zf-met[2],DZF[1]","family-846","ZFR,ZFR2","ZFR","ZFR2[42,48]","unknown","unknown","established RBP ",".",".",".",".",".",1,".",".","GO:0008270,GO:0003676","zinc ion binding,nucleic acid binding","."]
["AGFG1","ArfGAP with FG repeats 1 [Source:HGNC Symbol;Acc:5175]","ENSG00000173744","ENSP00000312059",1,"ArfGap[1]","family-847","AGFG1,AGFG2","AGFG1","AGFG2[36,44]","mRNA","mRNA",7634337,".",".",".",".",".",".","GO:0003723,GO:0006406","RNA binding,mRNA export from nucleus","GO:0043231,GO:0005794,GO:0003723,GO:0005515,GO:0008270,GO:0003677,GO:0008060,GO:0005643,GO:0016023,GO:0030154,GO:0007275,GO:0007283,GO:0032312,GO:0006406,GO:0043025,GO:0042995,GO:0001675,GO:0045109,GO:0007289","intracellular membrane-bounded organelle,Golgi apparatus,RNA binding,protein binding,zinc ion binding,DNA binding,ARF GTPase activator activity,nuclear pore,cytoplasmic membrane-bounded vesicle,cell differentiation,multicellular organismal development,spermatogenesis,regulation of ARF GTPase activity,mRNA export from nucleus,neuronal cell body,cell projection,acrosome assembly,intermediate filament organization,spermatid nucleus differentiation","."]
["NSA2","NSA2 ribosome biogenesis homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:30728]","ENSG00000164346","ENSP00000296802",1,"Ribosomal_S8e[1]","family-848","NSA2",".",".","rRNA","putative rRNA","This gene encodes a nucleolar protein involved in cell cycle regulation and proliferation. This gene was identified based on sequence similarity to a highly conserved Saccharomyces cerevisiae gene encoding a pre-ribosomal protein, which is involved in large ribosomal subunit biogenesis. The encoded protein is found at elevated levels in diabetic nephropathy. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified. [provided by RefSeq, Nov 2012]","candidate mRNA binder","RNArelated",1,1,1,".","GO:0030529,GO:0006364","ribonucleoprotein complex,rRNA processing","GO:0005730,GO:0030529,GO:0006364","nucleolus,ribonucleoprotein complex,rRNA processing","."]
["DDX10","DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Source:HGNC Symbol;Acc:2735]","ENSG00000178105","ENSP00000432032",4,"DUF4217[1],Helicase_C[1],Nop25[1],DEAD[1]","family-849","DDX10",".",".","rRNA","rRNA",23153376,"helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003724","RNA binding,RNA helicase activity","GO:0003723,GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003724","RNA binding,ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA helicase activity","."]
["TBL3","transducin (beta)-like 3 [Source:HGNC Symbol;Acc:11587]","ENSG00000183751","ENSP00000454836",9,"Utp13[1],WD40[8]","family-85","TBL3",".",".","snoRNA","snoRNA/rRNA","UTP13 yeast homolog",".","RNArelated",".",1,1,".","GO:0006364","rRNA processing","GO:0005515,GO:0032040,GO:0006364,GO:0005057,GO:0005634,GO:0005730,GO:0007199","protein binding,small-subunit processome,rRNA processing,receptor signaling protein activity,nucleus,nucleolus,G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger","."]
["INTS2","integrator complex subunit 2 [Source:HGNC Symbol;Acc:29241]","ENSG00000108506","ENSP00000414237",1,"INTS2[1]","family-850","INTS2",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0032039,GO:0016180,GO:0005515,GO:0016021,GO:0005622,GO:0031965","integrator complex,snRNA processing,protein binding,integral to membrane,intracellular,nuclear membrane","."]
["YBX1","Y box binding protein 1 [Source:HGNC Symbol;Acc:8014]","ENSG00000065978","ENSP00000361626",1,"CSD[1]","family-851","YBX1,YBX3,YBX2","YBX1","YBX3[58,50],YBX2[44,40]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0071204,GO:0030529,GO:0010494,GO:0005689,GO:0070937,GO:0008380,GO:0000398,GO:0070934","RNA binding,histone pre-mRNA 3'end processing complex,ribonucleoprotein complex,cytoplasmic stress granule,U12-type spliceosomal complex,CRD-mediated mRNA stability complex,RNA splicing,mRNA splicing, via spliceosome,CRD-mediated mRNA stabilization","GO:0003676,GO:0003677,GO:0006355,GO:0005737,GO:0043231,GO:0005515,GO:0003723,GO:0003700,GO:0003690,GO:0003697,GO:0005634,GO:0071204,GO:0005654,GO:0030529,GO:0070062,GO:0010494,GO:0005689,GO:0070937,GO:0000122,GO:0006366,GO:0045892,GO:0051781,GO:0010467,GO:0008380,GO:0001701,GO:0000398,GO:0070934,GO:0051154","nucleic acid binding,DNA binding,regulation of transcription, DNA-dependent,cytoplasm,intracellular membrane-bounded organelle,protein binding,RNA binding,sequence-specific DNA binding transcription factor activity,double-stranded DNA binding,single-stranded DNA binding,nucleus,histone pre-mRNA 3'end processing complex,nucleoplasm,ribonucleoprotein complex,extracellular vesicular exosome,cytoplasmic stress granule,U12-type spliceosomal complex,CRD-mediated mRNA stability complex,negative regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,negative regulation of transcription, DNA-dependent,positive regulation of cell division,gene expression,RNA splicing,in utero embryonic development,mRNA splicing, via spliceosome,CRD-mediated mRNA stabilization,negative regulation of striated muscle cell differentiation","."]
["YBX2","Y box binding protein 2 [Source:HGNC Symbol;Acc:17948]","ENSG00000006047","ENSP00000007699",1,"CSD[1]","family-851","YBX1,YBX3,YBX2","YBX1","YBX3[58,50],YBX2[44,40]","mRNA","mRNA","established RBP ",".",".",".",".",1,1,"GO:0003729,GO:0043021,GO:0003730,GO:0045182,GO:0030529,GO:0048255,GO:0009386","mRNA binding,ribonucleoprotein complex binding,mRNA 3'-UTR binding,translation regulator activity,ribonucleoprotein complex,mRNA stabilization,translational attenuation","GO:0003729,GO:0003676,GO:0003677,GO:0008289,GO:0003682,GO:0043021,GO:0003730,GO:0045182,GO:0030529,GO:0005634,GO:0005737,GO:0005844,GO:0048477,GO:0006366,GO:0007283,GO:0006355,GO:0007286,GO:0048599,GO:0017148,GO:0048255,GO:0051100,GO:0009386","mRNA binding,nucleic acid binding,DNA binding,lipid binding,chromatin binding,ribonucleoprotein complex binding,mRNA 3'-UTR binding,translation regulator activity,ribonucleoprotein complex,nucleus,cytoplasm,polysome,oogenesis,transcription from RNA polymerase II promoter,spermatogenesis,regulation of transcription, DNA-dependent,spermatid development,oocyte development,negative regulation of translation,mRNA stabilization,negative regulation of binding,translational attenuation","."]
["YBX3","cold shock domain protein A [Source:HGNC Symbol;Acc:2428]","ENSG00000060138","ENSP00000228251",1,"CSD[1]","family-851","YBX1,YBX3,YBX2","YBX1","YBX3[58,50],YBX2[44,40]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003730,GO:0030529,GO:0070935,GO:2000767","mRNA 3'-UTR binding,ribonucleoprotein complex,3'-UTR-mediated mRNA stabilization,positive regulation of cytoplasmic translation","GO:0005515,GO:0003730,GO:0003700,GO:0003714,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0017048,GO:0030529,GO:0005634,GO:0005737,GO:0005923,GO:0048471,GO:0005844,GO:0000122,GO:0006351,GO:0043066,GO:0007283,GO:0009566,GO:0006355,GO:0008584,GO:0001701,GO:0071356,GO:0009409,GO:0048642,GO:0046622,GO:0071474,GO:1902219,GO:0060547,GO:0070935,GO:2000767","protein binding,mRNA 3'-UTR binding,sequence-specific DNA binding transcription factor activity,transcription corepressor activity,nucleic acid binding,DNA binding,double-stranded DNA binding,single-stranded DNA binding,Rho GTPase binding,ribonucleoprotein complex,nucleus,cytoplasm,tight junction,perinuclear region of cytoplasm,polysome,negative regulation of transcription from RNA polymerase II promoter,transcription, DNA-templated,negative regulation of apoptotic process,spermatogenesis,fertilization,regulation of transcription, DNA-dependent,male gonad development,in utero embryonic development,cellular response to tumor necrosis factor,response to cold,negative regulation of skeletal muscle tissue development,positive regulation of organ growth,cellular hyperosmotic response,negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress,negative regulation of necrotic cell death,3'-UTR-mediated mRNA stabilization,positive regulation of cytoplasmic translation","."]
["SURF6","surfeit 6 [Source:HGNC Symbol;Acc:11478]","ENSG00000261306","ENSP00000457813",1,"SURF6[1]","family-852","SURF6",".",".","rRNA","putative rRNA"," 21063453,  This gene encodes a conserved protein that is localized to the nucleolus. The encoded protein may function as a nucleolar-matrix protein with nucleic acid-binding properties. There is a pseudogene for this gene on chromosome Y. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]","RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0042254","RNA binding,ribosome biogenesis","GO:0003723,GO:0003677,GO:0005730,GO:0005654,GO:0001652,GO:0042254","RNA binding,DNA binding,nucleolus,nucleoplasm,granular component,ribosome biogenesis","."]
["THOC6","THO complex 6 homolog (Drosophila) [Source:HGNC Symbol;Acc:28369]","ENSG00000131652","ENSP00000326531",1,"WD40[1]","family-853","THOC6",".",".","mRNA","mRNA",15998806,".",".",".",".",".",".","GO:0003723,GO:0000347,GO:0000445,GO:0006397,GO:0008380,GO:0006406","RNA binding,THO complex,THO complex part of transcription export complex,mRNA processing,RNA splicing,mRNA export from nucleus","GO:0003723,GO:0005515,GO:0005634,GO:0016607,GO:0000346,GO:0000347,GO:0000445,GO:0006915,GO:0043066,GO:0006397,GO:0008380,GO:0007417,GO:0006406,GO:0046784","RNA binding,protein binding,nucleus,nuclear speck,transcription export complex,THO complex,THO complex part of transcription export complex,apoptotic process,negative regulation of apoptotic process,mRNA processing,RNA splicing,central nervous system development,mRNA export from nucleus,viral mRNA export from host cell nucleus","."]
["EIF3I","eukaryotic translation initiation factor 3, subunit I [Source:HGNC Symbol;Acc:3272]","ENSG00000084623","ENSP00000362688",4,"WD40[4]","family-854","EIF3I,STRAP","EIF3I","STRAP[25,23]","mRNA","putative mRNA",19059401,".",".",".",".",".",".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0006413,GO:0006412,GO:0001731,GO:0006446","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translational initiation,translation,formation of translation preinitiation complex,regulation of translational initiation","GO:0005515,GO:0003743,GO:0005852,GO:0005829,GO:0016282,GO:0033290,GO:0006413,GO:0006412,GO:0010467,GO:0001731,GO:0006446,GO:0044267","protein binding,translation initiation factor activity,eukaryotic translation initiation factor 3 complex,cytosol,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,translational initiation,translation,gene expression,formation of translation preinitiation complex,regulation of translational initiation,cellular protein metabolic process","."]
["STRAP","serine/threonine kinase receptor associated protein [Source:HGNC Symbol;Acc:30796]","ENSG00000023734","ENSP00000392270",5,"WD40[5]","family-854","EIF3I,STRAP","EIF3I","STRAP[25,23]","mRNA","mRNA",23918805,"candidate mRNA binder","RNArelated",1,1,1,".","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0005515,GO:0016301,GO:0005102,GO:0000122,GO:0030512,GO:0005634,GO:0005886,GO:0005737,GO:0005739,GO:0005829,GO:0030054,GO:0005681,GO:0006397,GO:0008380,GO:0007179","protein binding,kinase activity,receptor binding,negative regulation of transcription from RNA polymerase II promoter,negative regulation of transforming growth factor beta receptor signaling pathway,nucleus,plasma membrane,cytoplasm,mitochondrion,cytosol,cell junction,spliceosomal complex,mRNA processing,RNA splicing,transforming growth factor beta receptor signaling pathway","."]
["RPL13","ribosomal protein L13 [Source:HGNC Symbol;Acc:10303]","ENSG00000167526","ENSP00000457686",1,"Ribosomal_L13e[1]","family-855","RPL13",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0022626,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,cytosolic ribosome,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0005515,GO:0003735,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0022626,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,protein binding,structural constituent of ribosome,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,cytosolic ribosome,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RRP12","ribosomal RNA processing 12 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:29100]","ENSG00000052749","ENSP00000446184",1,"NUC173[1]","family-856","RRP12",".",".","rRNA","putative rRNA","RRP12 homolog yeast Nucleolar protein; constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs ","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005488,GO:0016021,GO:0005730,GO:0031965","binding,integral to membrane,nucleolus,nuclear membrane","."]
["MRPS2","mitochondrial ribosomal protein S2 [Source:HGNC Symbol;Acc:14495]","ENSG00000122140","ENSP00000360850",1,"Ribosomal_S2[1]","family-857","MRPS2",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0015935,GO:0006412","structural constituent of ribosome,ribosome,small ribosomal subunit,translation","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0015935,GO:0006412","structural constituent of ribosome,mitochondrion,intracellular,ribosome,small ribosomal subunit,translation","."]
["ZCCHC8","zinc finger, CCHC domain containing 8 [Source:HGNC Symbol;Acc:25265]","ENSG00000033030","ENSP00000337313",2,"zf-CCHC[1],PSP[1]","family-858","ZCCHC8",".",".","mRNA","mRNA",16263084,".","RNArelated",".",1,1,".","GO:0071013,GO:0000398","catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0005515,GO:0008270,GO:0003676,GO:0005634,GO:0071013,GO:0000398","protein binding,zinc ion binding,nucleic acid binding,nucleus,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["EFTUD1","elongation factor Tu GTP binding domain containing 1 [Source:HGNC Symbol;Acc:25789]","ENSG00000140598","ENSP00000352418",4,"EFG_C[1],GTP_EFTU_D2[1],EFG_II[1],GTP_EFTU[1]","family-859","EFTUD1",".",".","tRNA","tRNA/mRNA","established RBP ",".",".",".",".",".",".","GO:0043022,GO:0003746,GO:0042256","ribosome binding,translation elongation factor activity,mature ribosome assembly","GO:0005525,GO:0003924,GO:0043022,GO:0003746,GO:0042256,GO:0006184","GTP binding,GTPase activity,ribosome binding,translation elongation factor activity,mature ribosome assembly,GTP catabolic process","."]
["RPL35","ribosomal protein L35 [Source:HGNC Symbol;Acc:10344]","ENSG00000136942","ENSP00000259469",1,"Ribosomal_L29[1]","family-86","RPL35",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003735,GO:0003729,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,mRNA binding,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0003729,GO:0005737,GO:0005829,GO:0005622,GO:0005730,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,mRNA binding,cytoplasm,cytosol,intracellular,nucleolus,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["NSRP1","nuclear speckle splicing regulatory protein 1 [Source:HGNC Symbol;Acc:25305]","ENSG00000126653","ENSP00000465442",1,"DUF2040[1]","family-860","NSRP1",".",".","mRNA","mRNA","by homology",".","experimentally validated",".",1,".",".","GO:0003729,GO:0030529,GO:0006397,GO:0008380,GO:0000381","mRNA binding,ribonucleoprotein complex,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome","GO:0005515,GO:0003729,GO:0005634,GO:0030529,GO:0016607,GO:0006397,GO:0008380,GO:0000381,GO:0006913,GO:0032502","protein binding,mRNA binding,nucleus,ribonucleoprotein complex,nuclear speck,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,nucleocytoplasmic transport,developmental process","."]
["RPUSD2","RNA pseudouridylate synthase domain containing 2 [Source:HGNC Symbol;Acc:24180]","ENSG00000166133","ENSP00000453036",1,"PseudoU_synth_2[1]","family-861","RPUSD2",".",".","tRNA","putative tRNA/rRNA","PUS9, RIB2 yeast homolog",".","RNAbinding",".",1,".",".","GO:0003723,GO:0009451","RNA binding,RNA modification","GO:0003723,GO:0009982,GO:0001522,GO:0009451","RNA binding,pseudouridine synthase activity,pseudouridine synthesis,RNA modification","."]
["BCDIN3D","BCDIN3 domain containing [Source:HGNC Symbol;Acc:27050]","ENSG00000186666","ENSP00000335201",1,"Bin3[1]","family-862","BCDIN3D",".",".","ncRNA","miRNA",23063121,".",".",".",".",".",".","GO:0008173,GO:0001510,GO:0010586,GO:2000632","RNA methyltransferase activity,RNA methylation,miRNA metabolic process,negative regulation of pre-miRNA processing","GO:0008168,GO:0008171,GO:0008173,GO:0005737,GO:0001510,GO:0010586,GO:2000632","methyltransferase activity,O-methyltransferase activity,RNA methyltransferase activity,cytoplasm,RNA methylation,miRNA metabolic process,negative regulation of pre-miRNA processing","."]
["THUMPD1","THUMP domain containing 1 [Source:HGNC Symbol;Acc:23807]","ENSG00000066654","ENSP00000392282",1,"THUMP[1]","family-863","THUMPD1",".",".","tRNA","putative tRNA","established RBP ",".","novel",".",1,1,1,"GO:0003723","RNA binding","GO:0003723","RNA binding","."]
["TRIM21","tripartite motif containing 21 [Source:HGNC Symbol;Acc:11312] [Type: protein coding Ensembl/Havana merge]","ENSG00000132109","ENSP00000254436",4,"SPRY[1],PRY[1],zf-C3HC4_4[1],zf-B_box[1]","family-864","TRIM21,TRIML1,TRIM27,TRIM17,TRIM4,TRIM68,TRIM11,TRIM39,TRIM7,TRIM60,TRIM34,TRIM6,TRIM22,TRIM5,TRIM38,TRIM58","TRIM21","TRIML1[37,38],TRIM27[38,35],TRIM17[36,35],TRIM4[35,33],TRIM68[42,41],TRIM11[41,42],TRIM39[41,38],TRIM7[36,33],TRIM60[35,35],TRIM34[20,19],TRIM6[45,41],TRIM22[41,39],TRIM5[41,40],TRIM38[41,42],TRIM58[43,42]","ncRNA","Y RNA","This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0030529","RNA binding,cytoplasmic mRNA processing body,ribonucleoprotein complex","GO:0005515,GO:0008270,GO:0046872,GO:0004842,GO:0005634,GO:0005737,GO:0005622,GO:0000151,GO:0016567,GO:0003723,GO:0003677,GO:0005829,GO:0000932,GO:0030529,GO:0019005,GO:0045087,GO:0000209,GO:0007049,GO:0032088,GO:0045787,GO:0051865,GO:0006513,GO:0032481,GO:0031648,GO:0032479,GO:0070206,GO:0090086","protein binding,zinc ion binding,metal ion binding,ubiquitin-protein ligase activity,nucleus,cytoplasm,intracellular,ubiquitin ligase complex,protein ubiquitination,RNA binding,DNA binding,cytosol,cytoplasmic mRNA processing body,ribonucleoprotein complex,SCF ubiquitin ligase complex,innate immune response,protein polyubiquitination,cell cycle,negative regulation of NF-kappaB transcription factor activity,positive regulation of cell cycle,protein autoubiquitination,protein monoubiquitination,positive regulation of type I interferon production,protein destabilization,regulation of type I interferon production,protein trimerization,negative regulation of protein deubiquitination","."]
["RANBP17","RAN binding protein 17 [Source:HGNC Symbol;Acc:14428]","ENSG00000204764","ENSP00000427975",2,"IBN_N[1],CRM1_C[1]","family-865","RANBP17,XPO7","RANBP17","XPO7[67,67]","mRNA","putative mRNA","The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]",".",".",".",".",".",".","GO:0051028","mRNA transport","GO:0005488,GO:0008536,GO:0006886,GO:0005634,GO:0005525,GO:0005737,GO:0005643,GO:0051028,GO:0006606","binding,Ran GTPase binding,intracellular protein transport,nucleus,GTP binding,cytoplasm,nuclear pore,mRNA transport,protein import into nucleus","."]
["XPO7","exportin 7 [Source:HGNC Symbol;Acc:14108]","ENSG00000130227","ENSP00000410249",2,"IBN_N[1],CRM1_C[1]","family-865","RANBP17,XPO7","RANBP17","XPO7[67,67]","mRNA","mRNA","The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]",".",".",".",".",".",".","GO:0051028","mRNA transport","GO:0005488,GO:0008536,GO:0005634,GO:0006886,GO:0005049,GO:0005737,GO:0005643,GO:0006611,GO:0051028","binding,Ran GTPase binding,nucleus,intracellular protein transport,nuclear export signal receptor activity,cytoplasm,nuclear pore,protein export from nucleus,mRNA transport","."]
["TRMT12","tRNA methyltransferase 12 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26091]","ENSG00000183665","ENSP00000329858",1,"Met_10[1]","family-866","TRMT12",".",".","tRNA","tRNA","Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0016740,GO:0008168,GO:0008033","transferase activity,methyltransferase activity,tRNA processing","."]
["ACIN1","apoptotic chromatin condensation inducer 1 [Source:HGNC Symbol;Acc:17066]","ENSG00000100813","ENSP00000262710",2,"SAP[1],RRM_5[1]","family-867","ACIN1",".",".","mRNA","mRNA"," This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing.","RNAbinding","novel",1,1,".",1,"GO:0003723,GO:0006397,GO:0008380,GO:0048025","RNA binding,mRNA processing,RNA splicing,negative regulation of mRNA splicing, via spliceosome","GO:0000166,GO:0003676,GO:0005634,GO:0005737,GO:0003723,GO:0005515,GO:0016887,GO:0019899,GO:0005829,GO:0016607,GO:0035145,GO:0061574,GO:0006915,GO:0006200,GO:0006397,GO:0008380,GO:0043065,GO:0030218,GO:0045657,GO:0048025,GO:0006921,GO:0030263,GO:0005730","nucleotide binding,nucleic acid binding,nucleus,cytoplasm,RNA binding,protein binding,ATPase activity,enzyme binding,cytosol,nuclear speck,exon-exon junction complex,ASAP complex,apoptotic process,ATP catabolic process,mRNA processing,RNA splicing,positive regulation of apoptotic process,erythrocyte differentiation,positive regulation of monocyte differentiation,negative regulation of mRNA splicing, via spliceosome,cellular component disassembly involved in execution phase of apoptosis,apoptotic chromosome condensation,nucleolus","."]
["ZNF385A","zinc finger protein 385A [Source:HGNC Symbol;Acc:17521]","ENSG00000161642","ENSP00000448567",3,"GVQW[1],zf-met[2]","family-868","ZNF385A,ZNF385B,ZNF385D,ZNF385C","ZNF385A","ZNF385B[47,39],ZNF385D[48,47],ZNF385C[37,31]","mRNA","mRNA","22681889, 22658674, 15527981","RNAbinding",".",".",1,".",".","GO:0003730,GO:0010609,GO:2000765,GO:0008298","mRNA 3'-UTR binding,mRNA localization resulting in posttranscriptional regulation of gene expression,regulation of cytoplasmic translation,intracellular mRNA localization","GO:0046872,GO:0003730,GO:0043025,GO:0030425,GO:0045600,GO:0007611,GO:0007626,GO:0035855,GO:0007599,GO:0030220,GO:0010609,GO:0070889,GO:2000765,GO:0008270,GO:0003676,GO:0003677,GO:0002039,GO:0005737,GO:0005730,GO:0000790,GO:0006351,GO:0006915,GO:0006974,GO:0006355,GO:1902166,GO:1902164,GO:0008298","metal ion binding,mRNA 3'-UTR binding,neuronal cell body,dendrite,positive regulation of fat cell differentiation,learning or memory,locomotory behavior,megakaryocyte development,hemostasis,platelet formation,mRNA localization resulting in posttranscriptional regulation of gene expression,platelet alpha granule organization,regulation of cytoplasmic translation,zinc ion binding,nucleic acid binding,DNA binding,p53 binding,cytoplasm,nucleolus,nuclear chromatin,transcription, DNA-templated,apoptotic process,cellular response to DNA damage stimulus,regulation of transcription, DNA-dependent,negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator,intracellular mRNA localization","."]
["RPL23","ribosomal protein L23 [Source:HGNC Symbol;Acc:10316]","ENSG00000125691","ENSP00000463894",1,"Ribosomal_L14[1]","family-869","RPL23",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0022625,GO:0016070,GO:0016071,GO:0006610,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,ribosomal protein import into nucleus,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005737,GO:0005840,GO:0006412,GO:0005730,GO:0005515,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006610,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytoplasm,ribosome,translation,nucleolus,protein binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,ribosomal protein import into nucleus,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["EED","embryonic ectoderm development [Source:HGNC Symbol;Acc:3188]","ENSG00000074266","ENSP00000263360",1,"WD40[1]","family-87","EED",".",".","ncRNA","lincRNA",24320048,".",".",".",".",1,".",".",".","GO:0005515,GO:0003682,GO:0035098,GO:0045120,GO:0001739,GO:0061087,GO:0006349,GO:0016571,GO:0042802,GO:0042054,GO:0005634,GO:0006351,GO:0045892","protein binding,chromatin binding,ESC/E(Z) complex,pronucleus,sex chromatin,positive regulation of histone H3-K27 methylation,regulation of gene expression by genetic imprinting,histone methylation,identical protein binding,histone methyltransferase activity,nucleus,transcription, DNA-templated,negative regulation of transcription, DNA-dependent","."]
["DNTTIP2","deoxynucleotidyltransferase, terminal, interacting protein 2 [Source:HGNC Symbol;Acc:24013]","ENSG00000067334","ENSP00000411010",1,"Fcf2[1]","family-870","DNTTIP2",".",".","rRNA","putative rRNA","by domain, This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005634,GO:0005730,GO:0006351,GO:0006355","nucleus,nucleolus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["SBDS","Shwachman-Bodian-Diamond syndrome [Source:HGNC Symbol;Acc:19440]","ENSG00000126524","ENSP00000246868",2,"SBDS_C[1],SBDS[1]","family-871","SBDS",".",".","rRNA","rRNA",23831625,".","experimentally validated",".",1,".",".","GO:0019843,GO:0043022,GO:0042254,GO:0006364,GO:0042256,GO:0042273","rRNA binding,ribosome binding,ribosome biogenesis,rRNA processing,mature ribosome assembly,ribosomal large subunit biogenesis","GO:0005515,GO:0008017,GO:0019843,GO:0043022,GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0000922,GO:0008283,GO:0042254,GO:0006364,GO:0030282,GO:0001833,GO:0042256,GO:0048539,GO:0042273,GO:0030595,GO:0043148","protein binding,microtubule binding,rRNA binding,ribosome binding,nucleus,cytoplasm,nucleolus,nucleoplasm,spindle pole,cell proliferation,ribosome biogenesis,rRNA processing,bone mineralization,inner cell mass cell proliferation,mature ribosome assembly,bone marrow development,ribosomal large subunit biogenesis,leukocyte chemotaxis,mitotic spindle stabilization"," SHWACHMAN-DIAMOND SYNDROME; SDS"]
["DDX51","DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 [Source:HGNC Symbol;Acc:20082]","ENSG00000185163","ENSP00000380495",2,"Helicase_C[1],DEAD[1]","family-872","DDX51",".",".","rRNA","putative rRNA","yeast homolog DBP6","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0006364","RNA binding,rRNA processing","GO:0003723,GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0004386,GO:0005730,GO:0006364","RNA binding,ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,nucleolus,rRNA processing","."]
["RBM18","RNA binding motif protein 18 [Source:HGNC Symbol;Acc:28413]","ENSG00000119446","ENSP00000409315",1,"RRM_1[1]","family-873","RBM18",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["IPO11","importin 11 [Source:HGNC Symbol;Acc:20628]","ENSG00000086200","ENSP00000427274",2,"IBN_N[1],Xpo1[1]","family-874","IPO11",".",".","mRNA","putative mRBP transport","Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]).[supplied by OMIM, Sep 2008]",".",".",".",".",".",".","GO:0006610","ribosomal protein import into nucleus","GO:0005488,GO:0008565,GO:0006610,GO:0005515,GO:0008536,GO:0005634,GO:0005737,GO:0006886","binding,protein transporter activity,ribosomal protein import into nucleus,protein binding,Ran GTPase binding,nucleus,cytoplasm,intracellular protein transport","."]
["RPL22","ribosomal protein L22 [Source:HGNC Symbol;Acc:10315]","ENSG00000116251","ENSP00000466013",1,"Ribosomal_L22e[1]","family-875","RPL22,RPL22L1","RPL22","RPL22L1[70,74]","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0030529,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,ribonucleoprotein complex,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0008201,GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0046632,GO:0003723,GO:0005737,GO:0005829,GO:0030529,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","heparin binding,structural constituent of ribosome,intracellular,ribosome,translation,alpha-beta T cell differentiation,RNA binding,cytoplasm,cytosol,ribonucleoprotein complex,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL22L1","ribosomal protein L22-like 1 [Source:HGNC Symbol;Acc:27610]","ENSG00000163584","ENSP00000419041",1,"Ribosomal_L22e[1]","family-875","RPL22,RPL22L1","RPL22","RPL22L1[70,74]","ribosome","ribosome","established RBP ",".",".",".",".",1,".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005622,GO:0005840,GO:0006412","structural constituent of ribosome,intracellular,ribosome,translation","."]
["LCMT2","leucine carboxyl methyltransferase 2 [Source:HGNC Symbol;Acc:17558]","ENSG00000168806","ENSP00000307214",3,"Kelch_6[2],LCM[1]","family-876","LCMT1,LCMT2","LCMT1","LCMT2[34,16]","tRNA","putative tRNA","PPM2 yeast homolog",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0008168,GO:0005515,GO:0008033,GO:0032259","methyltransferase activity,protein binding,tRNA processing,methylation","."]
["ZC3H11A","zinc finger CCCH-type containing 11A [Source:HGNC Symbol;Acc:29093]","ENSG00000058673","ENSP00000406531",1,"zf-CCCH_2[1]","family-877","ZC3H11A",".",".","unknown","unknown","by homology","candidate mRNA binder","novel",1,1,".",1,"GO:0016973","poly(A)+ mRNA export from nucleus","GO:0005515,GO:0046872,GO:0000346,GO:0016973","protein binding,metal ion binding,transcription export complex,poly(A)+ mRNA export from nucleus","."]
["FYTTD1","forty-two-three domain containing 1 [Source:HGNC Symbol;Acc:25407]","ENSG00000122068","ENSP00000241502",1,"FYTT[1]","family-878","FYTTD1",".",".","mRNA","mRNA","RNA export 19836239","RNAbinding",".",".",1,1,".","GO:0003729,GO:0006406","mRNA binding,mRNA export from nucleus","GO:0005515,GO:0003729,GO:0005654,GO:0016607,GO:0006406","protein binding,mRNA binding,nucleoplasm,nuclear speck,mRNA export from nucleus","."]
["RNPS1","RNA binding protein S1, serine-rich domain [Source:HGNC Symbol;Acc:10080]","ENSG00000205937","ENSP00000455306",1,"RRM_1[1]","family-879","RNPS1",".",".","mRNA","mRNA","This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]","RNAbinding","experimentally validated",1,1,".",1,"GO:0003730,GO:0016070,GO:0016071,GO:0008380,GO:0000381,GO:0000398,GO:0006406,GO:0031124,GO:0048025,GO:0000184","mRNA 3'-UTR binding,RNA metabolic process,mRNA metabolic process,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0000166,GO:0003676,GO:0005515,GO:0003730,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0016607,GO:0035145,GO:0061574,GO:0006351,GO:0006366,GO:0010467,GO:0016070,GO:0016071,GO:0008380,GO:0000381,GO:0000398,GO:0043065,GO:0006406,GO:0031124,GO:0048025,GO:0000184,GO:0006369","nucleotide binding,nucleic acid binding,protein binding,mRNA 3'-UTR binding,nucleus,cytoplasm,cytosol,nucleoplasm,nuclear speck,exon-exon junction complex,ASAP complex,transcription, DNA-templated,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,mRNA metabolic process,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,positive regulation of apoptotic process,mRNA export from nucleus,mRNA 3'-end processing,negative regulation of mRNA splicing, via spliceosome,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription","."]
["RPS23","ribosomal protein S23 [Source:HGNC Symbol;Acc:10410]","ENSG00000186468","ENSP00000296674",1,"Ribosom_S12_S23[1]","family-88","RPS23",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0015935,GO:0022627,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,small ribosomal subunit,cytosolic small ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0015935,GO:0005515,GO:0005829,GO:0022627,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,small ribosomal subunit,protein binding,cytosol,cytosolic small ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RNASEH2A","ribonuclease H2, subunit A [Source:HGNC Symbol;Acc:18518]","ENSG00000104889","ENSP00000221486",1,"RNase_HII[1]","family-880","RNASEH2A",".",".","diverse","RNA/DNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004540,GO:0004523,GO:0032299,GO:0016070,GO:0006401","RNA binding,ribonuclease activity,ribonuclease H activity,ribonuclease H2 complex,RNA metabolic process,RNA catabolic process","GO:0003723,GO:0003676,GO:0046872,GO:0004540,GO:0004523,GO:0032299,GO:0005634,GO:0016070,GO:0006260,GO:0006401","RNA binding,nucleic acid binding,metal ion binding,ribonuclease activity,ribonuclease H activity,ribonuclease H2 complex,nucleus,RNA metabolic process,DNA replication,RNA catabolic process"," AICARDI-GOUTIERES SYNDROME 4; AGS4"]
["FRG1B","FSHD region gene 1 family, member B [Source:HGNC Symbol;Acc:15792]","ENSG00000149531","ENSP00000351249",1,"FRG1[1]","family-881","FRG1,FRG1B","FRG1","FRG1B[60,86]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["FRG1","FSHD region gene 1 [Source:HGNC Symbol;Acc:3954]","ENSG00000260380","ENSP00000455022",1,"FRG1[1]","family-881","FRG1,FRG1B","FRG1","FRG1B[60,86]","mRNA","putative mRNA, rRNA","by homology, 21699900",".","RNArelated",".",1,1,".","GO:0071013,GO:0000398,GO:0006364","catalytic step 2 spliceosome,mRNA splicing, via spliceosome,rRNA processing","GO:0051015,GO:0030674,GO:0005515,GO:0005730,GO:0016607,GO:0015030,GO:0071013,GO:0000398,GO:0006364","actin filament binding,protein binding, bridging,protein binding,nucleolus,nuclear speck,Cajal body,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,rRNA processing","."]
["NOL7","nucleolar protein 7, 27kDa [Source:HGNC Symbol;Acc:21040]","ENSG00000225921","ENSP00000405674",1,"NUC129[1]","family-882","NOL7",".",".","unknown","unknown","established RBP ",".","novel",".",1,1,".",".",".","GO:0005634,GO:0005739,GO:0005730","nucleus,mitochondrion,nucleolus","."]
["PRPF38A","PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [Source:HGNC Symbol;Acc:25930]","ENSG00000134748","ENSP00000257181",2,"PRP38_assoc[1],PRP38[1]","family-883","PRPF38A",".",".","snRNA","putative snRNA /mRNA","Unique component of the U4/U6.U5 tri-snRNP particle; tri-snRNP is required for conformational changes which result in the catalytic activation of the spliceosome; dispensable for spliceosome assembly","candidate mRNA binder",".",".",1,".",".","GO:0005681,GO:0006397,GO:0008380","spliceosomal complex,mRNA processing,RNA splicing","GO:0005515,GO:0005681,GO:0006397,GO:0008380","protein binding,spliceosomal complex,mRNA processing,RNA splicing","."]
["RBM41","RNA binding motif protein 41 [Source:HGNC Symbol;Acc:25617]","ENSG00000089682","ENSP00000361557",1,"RRM_1[1]","family-884","RBM41",".",".","mRNA","putative mRNA","by homology",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["RBM12","RNA binding motif protein 12 [Source:HGNC Symbol;Acc:9898]","ENSG00000244462","ENSP00000352668",5,"RRM_1[1],RRM_6[4]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723","RNA binding","GO:0000166,GO:0005634,GO:0003723,GO:0003676","nucleotide binding,nucleus,RNA binding,nucleic acid binding","."]
["RBM12B","RNA binding motif protein 12B [Source:HGNC Symbol;Acc:32310]","ENSG00000183808","ENSP00000427729",5,"RRM_6[5]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0003723,GO:0005515","nucleotide binding,nucleic acid binding,RNA binding,protein binding","."]
["ESRP1","epithelial splicing regulatory protein 1 [Source:HGNC Symbol;Acc:25966]","ENSG00000104413","ENSP00000430118",3,"RRM_6[3]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","ESPR1 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]",".",".",".",".",1,1,"GO:0003729,GO:0006397,GO:0008380,GO:0043484","mRNA binding,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0000166,GO:0003676,GO:0003729,GO:0005634,GO:0005886,GO:0006397,GO:0008380,GO:0043484","nucleotide binding,nucleic acid binding,mRNA binding,nucleus,plasma membrane,mRNA processing,RNA splicing,regulation of RNA splicing","."]
["ESRP2","epithelial splicing regulatory protein 2 [Source:HGNC Symbol;Acc:26152]","ENSG00000103067","ENSP00000454554",3,"RRM_6[3]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","ESPR2 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003729,GO:0006397,GO:0008380,GO:0043484","mRNA binding,mRNA processing,RNA splicing,regulation of RNA splicing","GO:0000166,GO:0003676,GO:0003729,GO:0005634,GO:0005737,GO:0005739,GO:0005813,GO:0006397,GO:0008380,GO:0043484","nucleotide binding,nucleic acid binding,mRNA binding,nucleus,cytoplasm,mitochondrion,centrosome,mRNA processing,RNA splicing,regulation of RNA splicing","."]
["HNRNPF","heterogeneous nuclear ribonucleoprotein F [Source:HGNC Symbol;Acc:5039]","ENSG00000169813","ENSP00000400433",4,"zf-RNPHF[1],RRM_1[1],RRM_6[2]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003727,GO:0071013,GO:0008380,GO:0000398,GO:0006396,GO:0043484","RNA binding,single-stranded RNA binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA processing,regulation of RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003727,GO:0005634,GO:0005737,GO:0005654,GO:0071013,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0043484","nucleotide binding,RNA binding,protein binding,nucleic acid binding,single-stranded RNA binding,nucleus,cytoplasm,nucleoplasm,catalytic step 2 spliceosome,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,regulation of RNA splicing","."]
["HNRNPH1","heterogeneous nuclear ribonucleoprotein H1 (H) [Source:HGNC Symbol;Acc:5041]","ENSG00000169045","ENSP00000377082",4,"zf-RNPHF[1],RRM_6[3]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0008266,GO:0071013,GO:0008380,GO:0000398,GO:0006396,GO:0043484","RNA binding,poly(U) RNA binding,catalytic step 2 spliceosome,RNA splicing,mRNA splicing, via spliceosome,RNA processing,regulation of RNA splicing","GO:0000166,GO:0003676,GO:0005634,GO:0015629,GO:0005737,GO:0003723,GO:0005515,GO:0008266,GO:0005654,GO:0071013,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0043484","nucleotide binding,nucleic acid binding,nucleus,actin cytoskeleton,cytoplasm,RNA binding,protein binding,poly(U) RNA binding,nucleoplasm,catalytic step 2 spliceosome,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,regulation of RNA splicing","."]
["HNRNPH2","heterogeneous nuclear ribonucleoprotein H2 (H') [Source:HGNC Symbol;Acc:5042]","ENSG00000126945","ENSP00000361927",4,"zf-RNPHF[1],RRM_6[3]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0030529,GO:0008380,GO:0000398","RNA binding,ribonucleoprotein complex,RNA splicing,mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0003676,GO:0005634,GO:0005737,GO:0005654,GO:0030529,GO:0015629,GO:0010467,GO:0008380,GO:0000398","nucleotide binding,RNA binding,nucleic acid binding,nucleus,cytoplasm,nucleoplasm,ribonucleoprotein complex,actin cytoskeleton,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["HNRNPH3","heterogeneous nuclear ribonucleoprotein H3 (2H9) [Source:HGNC Symbol;Acc:5043]","ENSG00000096746","ENSP00000265866",2,"RRM_6[2]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","established RBP ","RNAbinding","experimentally validated",1,1,1,1,"GO:0030529,GO:0003723,GO:0008380,GO:0000398,GO:0006396","ribonucleoprotein complex,RNA binding,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0000166,GO:0003676,GO:0005634,GO:0030529,GO:0019013,GO:0003723,GO:0008380,GO:0000398,GO:0006396","nucleotide binding,nucleic acid binding,nucleus,ribonucleoprotein complex,viral nucleocapsid,RNA binding,RNA splicing,mRNA splicing, via spliceosome,RNA processing","."]
["GRSF1","G-rich RNA sequence binding factor 1 [Source:HGNC Symbol;Acc:4610]","ENSG00000132463","ENSP00000254799",3,"RRM_6[3]","family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","HNRNPF","RBM12[20,9],ESRP1[28,17],RBM12B[21,9],ESRP2[27,15],HNRNPH1[77,71],HNRNPH2[75,69],HNRNPH3[45,54],GRSF1[35,30]","mRNA","mRNA","The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,1,1,"GO:0003723,GO:0003729,GO:0008033,GO:0006378","RNA binding,mRNA binding,tRNA processing,mRNA polyadenylation","GO:0000166,GO:0003723,GO:0003676,GO:0003729,GO:0005737,GO:0005739,GO:0042645,GO:0008033,GO:0009952,GO:0006378,GO:0016331","nucleotide binding,RNA binding,nucleic acid binding,mRNA binding,cytoplasm,mitochondrion,mitochondrial nucleoid,tRNA processing,anterior/posterior pattern specification,mRNA polyadenylation,morphogenesis of embryonic epithelium","."]
["RNH1","ribonuclease/angiogenin inhibitor 1 [Source:HGNC Symbol;Acc:10074]","ENSG00000023191","ENSP00000433999",2,"LRR_8[1],LRR_4[1]","family-886","RNH1",".",".","diverse","putative diverse","inhibitor of ANG",".",".",".",".",".",".","GO:0008428,GO:0006402","ribonuclease inhibitor activity,mRNA catabolic process","GO:0005515,GO:0008428,GO:0005737,GO:0032311,GO:0006402,GO:0045765","protein binding,ribonuclease inhibitor activity,cytoplasm,angiogenin-PRI complex,mRNA catabolic process,regulation of angiogenesis","."]
["NOL9","nucleolar protein 9 [Source:HGNC Symbol;Acc:26265]","ENSG00000162408","ENSP00000366934",1,"Clp1[1]","family-887","NOL9",".",".","rRNA","rRNA",21063389,".",".",".",".",".",".","GO:0003723,GO:0000460","RNA binding,maturation of 5.8S rRNA","GO:0003723,GO:0005524,GO:0051731,GO:0005730,GO:0000460","RNA binding,ATP binding,polynucleotide 5'-hydroxyl-kinase activity,nucleolus,maturation of 5.8S rRNA","."]
["SRFBP1","serum response factor binding protein 1 [Source:HGNC Symbol;Acc:26333]","ENSG00000151304","ENSP00000341324",1,"BUD22[1]","family-888","SRFBP1",".",".","rRNA","putative rRNA","during translational initiation and general transcription regulation. ","candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005515,GO:0005634,GO:0048471,GO:0006351,GO:0006355","protein binding,nucleus,perinuclear region of cytoplasm,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["ARL6IP4","ADP-ribosylation-like factor 6 interacting protein 4 [Source:HGNC Symbol;Acc:18076]","ENSG00000182196","ENSP00000376230",1,"SR-25[1]","family-889","ARL6IP4",".",".","mRNA","mRNA",11884129,"candidate mRNA binder","RNArelated",1,1,".",".","GO:0008380","RNA splicing","GO:0005515,GO:0005634,GO:0008380","protein binding,nucleus,RNA splicing","."]
["RPP40","ribonuclease P/MRP 40kDa subunit [Source:HGNC Symbol;Acc:20992]","ENSG00000124787","ENSP00000317998",1,"Ribonuc_P_40[1]","family-89","RPP40",".",".","ncRNA","P/MRP RNA",15096576,".",".",".",".",".",".","GO:0004526,GO:0005655,GO:0008033","ribonuclease P activity,nucleolar ribonuclease P complex,tRNA processing","GO:0004526,GO:0005634,GO:0005655,GO:0008033","ribonuclease P activity,nucleus,nucleolar ribonuclease P complex,tRNA processing","."]
["ALKBH5","alkB, alkylation repair homolog 5 (E. coli) [Source:HGNC Symbol;Acc:25996]","ENSG00000091542","ENSP00000382091",1,"2OG-FeII_Oxy_2[1]","family-890","ALKBH5",".",".","mRNA","mRNA",23177736,"candidate mRNA binder","novel",1,1,".",".","GO:0035515,GO:0006397,GO:0035553,GO:0006406","oxidative RNA demethylase activity,mRNA processing,oxidative single-stranded RNA demethylation,mRNA export from nucleus","GO:0046872,GO:0016706,GO:0035515,GO:0005634,GO:0016607,GO:0030154,GO:0007283,GO:0001666,GO:0006397,GO:0035553,GO:0006406","metal ion binding,oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors,oxidative RNA demethylase activity,nucleus,nuclear speck,cell differentiation,spermatogenesis,response to hypoxia,mRNA processing,oxidative single-stranded RNA demethylation,mRNA export from nucleus","."]
["SMG7","smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:16792]","ENSG00000116698","ENSP00000425133",1,"EST1_DNA_bind[1]","family-891","SMG7",".",".","mRNA","mRNA","This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]",".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0006406,GO:0000184","RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005737,GO:0045111,GO:0005515,GO:0051721,GO:0005634,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0006406,GO:0000184,GO:0035303","cytoplasm,intermediate filament cytoskeleton,protein binding,protein phosphatase 2A binding,nucleus,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of dephosphorylation","."]
["PDE12","phosphodiesterase 12 [Source:HGNC Symbol;Acc:25386]","ENSG00000174840","ENSP00000309142",1,"Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","mRNA",21666256,".",".",".",".",".",".","GO:0004535,GO:0006397","poly(A)-specific ribonuclease activity,mRNA processing","GO:0046872,GO:0004535,GO:0005739,GO:0005759,GO:0006397","metal ion binding,poly(A)-specific ribonuclease activity,mitochondrion,mitochondrial matrix,mRNA processing","."]
["CCRN4L","CCR4 carbon catabolite repression 4-like (S. cerevisiae) [Source:HGNC Symbol;Acc:14254]","ENSG00000151014","ENSP00000280614",1,"Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","mRNA",22547059,".",".",".",".",".",".","GO:0004535,GO:0000932,GO:0006397,GO:0000290,GO:0033962","poly(A)-specific ribonuclease activity,cytoplasmic mRNA processing body,mRNA processing,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly","GO:0005515,GO:0003700,GO:0046872,GO:0004535,GO:0005634,GO:0000932,GO:0005654,GO:0006366,GO:0006355,GO:0006397,GO:0000290,GO:0033962,GO:0048511","protein binding,sequence-specific DNA binding transcription factor activity,metal ion binding,poly(A)-specific ribonuclease activity,nucleus,cytoplasmic mRNA processing body,nucleoplasm,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent,mRNA processing,deadenylation-dependent decapping of nuclear-transcribed mRNA,cytoplasmic mRNA processing body assembly,rhythmic process","."]
["ANGEL1","angel homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:19961]","ENSG00000013523","ENSP00000451534",1,"Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["ANGEL2","angel homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:30534]","ENSG00000174606","ENSP00000438141",1,"Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","putative mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["CNOT6","CCR4-NOT transcription complex, subunit 6 [Source:HGNC Symbol;Acc:14099]","ENSG00000113300","ENSP00000261951",2,"LRR_8[1],Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0004535,GO:0004532,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0035195,GO:0043928,GO:0070966","RNA binding,poly(A)-specific ribonuclease activity,exoribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear-transcribed mRNA catabolic process, no-go decay","GO:0003723,GO:0005515,GO:0046872,GO:0004535,GO:0004532,GO:0005634,GO:0005829,GO:0030014,GO:0006351,GO:0006355,GO:0008284,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0035195,GO:0043928,GO:0070966,GO:2000327","RNA binding,protein binding,metal ion binding,poly(A)-specific ribonuclease activity,exoribonuclease activity,nucleus,cytosol,CCR4-NOT complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,positive regulation of cell proliferation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by miRNA,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear-transcribed mRNA catabolic process, no-go decay,positive regulation of ligand-dependent nuclear receptor transcription coactivator activity","."]
["CNOT6L","CCR4-NOT transcription complex, subunit 6-like [Source:HGNC Symbol;Acc:18042]","ENSG00000138767","ENSP00000423750",2,"LRR_8[1],Exo_endo_phos[1]","family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","ANGEL1","ANGEL2[33,41],CCRN4L[16,25],CNOT6[17,21],CNOT6L[17,21],PDE12[17,19]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0004535,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047,GO:0061157","poly(A)-specific ribonuclease activity,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA,mRNA destabilization","GO:0005515,GO:0046872,GO:0004535,GO:0005634,GO:0005737,GO:0005829,GO:0030014,GO:0006351,GO:0006355,GO:0008284,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0010606,GO:0031047,GO:0061157","protein binding,metal ion binding,poly(A)-specific ribonuclease activity,nucleus,cytoplasm,cytosol,CCR4-NOT complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,positive regulation of cell proliferation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,positive regulation of cytoplasmic mRNA processing body assembly,gene silencing by RNA,mRNA destabilization","."]
["PDCD11","programmed cell death 11 [Source:HGNC Symbol;Acc:13408]","ENSG00000148843","ENSP00000358812",6,"S1[5],Suf[1]","family-893","PDCD11",".",".","snoRNA","snoRNA/rRNA",19332556,".","RNAbinding",".",1,1,1,"GO:0003723,GO:0006397,GO:0006364,GO:0006396","RNA binding,mRNA processing,rRNA processing,RNA processing","GO:0003723,GO:0005515,GO:0008134,GO:0005634,GO:0005829,GO:0005622,GO:0005730,GO:0006397,GO:0006364,GO:0006396","RNA binding,protein binding,transcription factor binding,nucleus,cytosol,intracellular,nucleolus,mRNA processing,rRNA processing,RNA processing","."]
["RPL35A","ribosomal protein L35a [Source:HGNC Symbol;Acc:10345]","ENSG00000182899","ENSP00000419117",1,"Ribosomal_L35Ae[1]","family-894","RPL35A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0000049,GO:0022625,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,tRNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0000049,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,tRNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription"," DIAMOND-BLACKFAN ANEMIA 5; DBA5"]
["MRPL21","mitochondrial ribosomal protein L21 [Source:HGNC Symbol;Acc:14479]","ENSG00000197345","ENSP00000389400",1,"Ribosomal_L21p[1]","family-895","MRPL21",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003723,GO:0003735,GO:0005840,GO:0006412","RNA binding,structural constituent of ribosome,ribosome,translation","GO:0005739,GO:0003723,GO:0003735,GO:0005622,GO:0005840,GO:0006412","mitochondrion,RNA binding,structural constituent of ribosome,intracellular,ribosome,translation","."]
["SMG6","smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:17809]","ENSG00000070366","ENSP00000263073",3,"PIN_4[1],EST1[1],EST1_DNA_bind[1]","family-896","SMG6",".",".","mRNA","mRNA","This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. [provided by RefSeq, Feb 2014]",".",".",".",".",".",".","GO:0004521,GO:0005697,GO:0016070,GO:0016071,GO:0006406,GO:0000184","endoribonuclease activity,telomerase holoenzyme complex,RNA metabolic process,mRNA metabolic process,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005515,GO:0046872,GO:0042162,GO:0004521,GO:0005634,GO:0005737,GO:0005829,GO:0005730,GO:0000781,GO:0035145,GO:0005697,GO:0010467,GO:0016070,GO:0016071,GO:0000723,GO:0006406,GO:0000184,GO:0035303","protein binding,metal ion binding,telomeric DNA binding,endoribonuclease activity,nucleus,cytoplasm,cytosol,nucleolus,chromosome, telomeric region,exon-exon junction complex,telomerase holoenzyme complex,gene expression,RNA metabolic process,mRNA metabolic process,telomere maintenance,mRNA export from nucleus,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,regulation of dephosphorylation","."]
["PRPF19","PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:17896]","ENSG00000110107","ENSP00000227524",6,"Prp19[1],U-box[1],WD40[4]","family-897","PRPF19,PRPF4","PRPF19","PRPF4[20,19]","mRNA","mRNA",22967061,".",".",".",".",".",".","GO:0048026,GO:0071013,GO:0000398,GO:0000245","positive regulation of mRNA splicing, via spliceosome,catalytic step 2 spliceosome,mRNA splicing, via spliceosome,spliceosomal complex assembly","GO:0005634,GO:0005811,GO:0045665,GO:0001833,GO:0008610,GO:0048026,GO:0048711,GO:0005515,GO:0004842,GO:0000151,GO:0016567,GO:0003677,GO:0034450,GO:0042802,GO:0005737,GO:0005819,GO:0016607,GO:0071013,GO:0000974,GO:0000209,GO:0006281,GO:0000398,GO:0000245","nucleus,lipid particle,negative regulation of neuron differentiation,inner cell mass cell proliferation,lipid biosynthetic process,positive regulation of mRNA splicing, via spliceosome,positive regulation of astrocyte differentiation,protein binding,ubiquitin-protein ligase activity,ubiquitin ligase complex,protein ubiquitination,DNA binding,ubiquitin-ubiquitin ligase activity,identical protein binding,cytoplasm,spindle,nuclear speck,catalytic step 2 spliceosome,Prp19 complex,protein polyubiquitination,DNA repair,mRNA splicing, via spliceosome,spliceosomal complex assembly","."]
["PRPF4","PRP4 pre-mRNA processing factor 4 homolog (yeast) [Source:HGNC Symbol;Acc:17349]","ENSG00000136875","ENSP00000363313",8,"PRP4[1],WD40[7]","family-897","PRPF19,PRPF4","PRPF19","PRPF4[20,19]","snRNA","snRNA/mRNA","Splicing factor; component of the U4/U6-U5 snRNP complex, yeast homolog PRP4",".",".",".",".",".",".","GO:0005681,GO:0071001,GO:0008380,GO:0000398,GO:0006396,GO:0000375","spliceosomal complex,U4/U6 snRNP,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA splicing, via transesterification reactions","GO:0005515,GO:0005634,GO:0005654,GO:0005681,GO:0016607,GO:0015030,GO:0071001,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0000375","protein binding,nucleus,nucleoplasm,spliceosomal complex,nuclear speck,Cajal body,U4/U6 snRNP,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,RNA splicing, via transesterification reactions","."]
["INTS4","integrator complex subunit 4 [Source:HGNC Symbol;Acc:25048]","ENSG00000149262","ENSP00000434466",2,"HEAT_2[2]","family-898","INTS4",".",".","snRNA","snRNA","established RBP ",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0032039,GO:0016180,GO:0005488","protein binding,integrator complex,snRNA processing,binding","."]
["SRPK2","SRSF protein kinase 2 [Source:HGNC Symbol;Acc:11306]","ENSG00000135250","ENSP00000349863",2,"Pkinase[2]","family-899","SRPK1,SRPK2,SRPK3","SRPK1","SRPK2[61,57],SRPK3[51,58]","mRNA","putative mRNA",9472028,"candidate mRNA binder","RNArelated",1,1,".",".","GO:0008380,GO:0000245,GO:0048024","RNA splicing,spliceosomal complex assembly,regulation of mRNA splicing, via spliceosome","GO:0005524,GO:0004672,GO:0016772,GO:0006468,GO:0005515,GO:0004674,GO:0000287,GO:0004713,GO:0071889,GO:0005634,GO:0005737,GO:0005730,GO:0045087,GO:0030154,GO:0008284,GO:0001525,GO:0035556,GO:0008380,GO:0045071,GO:0010628,GO:0045787,GO:0043525,GO:0000245,GO:0045070,GO:0048024,GO:0035063","ATP binding,protein kinase activity,transferase activity, transferring phosphorus-containing groups,protein phosphorylation,protein binding,protein serine/threonine kinase activity,magnesium ion binding,protein tyrosine kinase activity,14-3-3 protein binding,nucleus,cytoplasm,nucleolus,innate immune response,cell differentiation,positive regulation of cell proliferation,angiogenesis,intracellular signal transduction,RNA splicing,negative regulation of viral genome replication,positive regulation of gene expression,positive regulation of cell cycle,positive regulation of neuron apoptotic process,spliceosomal complex assembly,positive regulation of viral genome replication,regulation of mRNA splicing, via spliceosome,nuclear speck organization","."]
["SUPV3L1","suppressor of var1, 3-like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:11471]","ENSG00000156502","ENSP00000352678",2,"Helicase_C[1],SUV3_C[1]","family-9","SUPV3L1",".",".","mRNA","mRNA",15919122,"helicase","experimentally validated",1,1,".",".","GO:0003723,GO:0003725,GO:0004004,GO:0034458,GO:0006401,GO:0000958,GO:0000962,GO:0000965,GO:0035945,GO:0035946,GO:2000827","RNA binding,double-stranded RNA binding,ATP-dependent RNA helicase activity,3'-5' RNA helicase activity,RNA catabolic process,mitochondrial mRNA catabolic process,positive regulation of mitochondrial RNA catabolic process,mitochondrial RNA 3'-end processing,mitochondrial ncRNA surveillance,mitochondrial mRNA surveillance,mitochondrial RNA surveillance","GO:0005524,GO:0003676,GO:0004386,GO:0003723,GO:0005515,GO:0042803,GO:0016817,GO:0003677,GO:0003725,GO:0003678,GO:0004004,GO:0034458,GO:0005739,GO:0005634,GO:0005759,GO:0042645,GO:0045025,GO:0043066,GO:0006310,GO:0030307,GO:0070584,GO:0032508,GO:0006401,GO:0000958,GO:0000962,GO:0000965,GO:0035945,GO:0035946,GO:0070827,GO:2000827","ATP binding,nucleic acid binding,helicase activity,RNA binding,protein binding,protein homodimerization activity,hydrolase activity, acting on acid anhydrides,DNA binding,double-stranded RNA binding,DNA helicase activity,ATP-dependent RNA helicase activity,3'-5' RNA helicase activity,mitochondrion,nucleus,mitochondrial matrix,mitochondrial nucleoid,mitochondrial degradosome,negative regulation of apoptotic process,DNA recombination,positive regulation of cell growth,mitochondrion morphogenesis,DNA duplex unwinding,RNA catabolic process,mitochondrial mRNA catabolic process,positive regulation of mitochondrial RNA catabolic process,mitochondrial RNA 3'-end processing,mitochondrial ncRNA surveillance,mitochondrial mRNA surveillance,chromatin maintenance,mitochondrial RNA surveillance","."]
["RBM17","RNA binding motif protein 17 [Source:HGNC Symbol;Acc:16944]","ENSG00000134453","ENSP00000369218",2,"G-patch[1],RRM_5[1]","family-90","RBM17",".",".","mRNA","mRNA","This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]",".",".",".",".",".",1,"GO:0003723,GO:0005681,GO:0006397,GO:0008380","RNA binding,spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0005634,GO:0005681,GO:0006397,GO:0008380","nucleotide binding,RNA binding,protein binding,nucleic acid binding,nucleus,spliceosomal complex,mRNA processing,RNA splicing","."]
["NAF1","nuclear assembly factor 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25126]","ENSG00000145414","ENSP00000274054",1,"Gar1[1]","family-900","NAF1",".",".","snoRNA","snoRNA",17135485,"RNAbinding",".",".",1,".",".","GO:0003723,GO:0005732,GO:0042254,GO:0006364","RNA binding,small nucleolar ribonucleoprotein complex,ribosome biogenesis,rRNA processing","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0030054,GO:0005813,GO:0005732,GO:0042254,GO:0006364,GO:0001522","RNA binding,protein binding,nucleus,cytoplasm,cell junction,centrosome,small nucleolar ribonucleoprotein complex,ribosome biogenesis,rRNA processing,pseudouridine synthesis","."]
["YARS","tyrosyl-tRNA synthetase [Source:HGNC Symbol;Acc:12840]","ENSG00000134684","ENSP00000362576",2,"tRNA_bind[1],tRNA-synt_1b[1]","family-901","YARS",".",".","tRNA","tRNA","established RBP ",".","RNAbinding",".",1,".",".","GO:0000049,GO:0004812,GO:0004831,GO:0006418,GO:0006437","tRNA binding,aminoacyl-tRNA ligase activity,tyrosine-tRNA ligase activity,tRNA aminoacylation for protein translation,tyrosyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004871,GO:0000049,GO:0004812,GO:0005153,GO:0004831,GO:0005634,GO:0005737,GO:0005829,GO:0005615,GO:0006915,GO:0007165,GO:0010467,GO:0006418,GO:0006437","nucleotide binding,ATP binding,signal transducer activity,tRNA binding,aminoacyl-tRNA ligase activity,interleukin-8 receptor binding,tyrosine-tRNA ligase activity,nucleus,cytoplasm,cytosol,extracellular space,apoptotic process,signal transduction,gene expression,tRNA aminoacylation for protein translation,tyrosyl-tRNA aminoacylation"," CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE C; CMTDIC"]
["LRRFIP1","leucine rich repeat (in FLII) interacting protein 1 [Source:HGNC Symbol;Acc:6702]","ENSG00000124831","ENSP00000310109",3,"DUF2051[3]","family-902","LRRFIP1,LRRFIP2","LRRFIP1","LRRFIP2[23,26]","ncRNA","ncRNA"," 24567534, 21102652",".",".",".",".",".",".","GO:0003725","double-stranded RNA binding","GO:0005515,GO:0042803,GO:0003677,GO:0003725,GO:0005634,GO:0005737,GO:0005829,GO:0005856,GO:0006351,GO:0045087,GO:0045892,GO:0006357,GO:0032481","protein binding,protein homodimerization activity,DNA binding,double-stranded RNA binding,nucleus,cytoplasm,cytosol,cytoskeleton,transcription, DNA-templated,innate immune response,negative regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter,positive regulation of type I interferon production","."]
["LRRFIP2","leucine rich repeat (in FLII) interacting protein 2 [Source:HGNC Symbol;Acc:6703]","ENSG00000093167","ENSP00000392217",3,"DUF2051[2],TPR_MLP1_2[1]","family-902","LRRFIP1,LRRFIP2","LRRFIP1","LRRFIP2[23,26]","ncRNA","putative ncRNA","by homology",".",".",".",".",".",".",".",".","GO:0005515,GO:0046983,GO:0030275,GO:0016055","protein binding,protein dimerization activity,LRR domain binding,Wnt signaling pathway","."]
["EIF4E2","eukaryotic translation initiation factor 4E family member 2 [Source:HGNC Symbol;Acc:3293]","ENSG00000135930","ENSP00000258416",1,"IF4E[1]","family-903","EIF4E,EIF4E1B,EIF4E3,EIF4E2","EIF4E","EIF4E1B[56,57],EIF4E3[22,25],EIF4E2[29,29]","mRNA","mRNA",17369309,"translationfactor",".",".",1,".",".","GO:0003723,GO:0003743,GO:0006413,GO:0000339,GO:0008135,GO:0005845","RNA binding,translation initiation factor activity,translational initiation,RNA cap binding,translation factor activity, nucleic acid binding,mRNA cap binding complex","GO:0003723,GO:0003743,GO:0005737,GO:0006413,GO:0005515,GO:0031625,GO:0000339,GO:0008135,GO:0005829,GO:0005845,GO:0001701,GO:0019221,GO:0017148","RNA binding,translation initiation factor activity,cytoplasm,translational initiation,protein binding,ubiquitin protein ligase binding,RNA cap binding,translation factor activity, nucleic acid binding,cytosol,mRNA cap binding complex,in utero embryonic development,cytokine-mediated signaling pathway,negative regulation of translation","."]
["EIF4E1B","eukaryotic translation initiation factor 4E family member 1B [Source:HGNC Symbol;Acc:33179]","ENSG00000175766","ENSP00000422420",1,"IF4E[1]","family-903","EIF4E,EIF4E1B,EIF4E3,EIF4E2","EIF4E","EIF4E1B[56,57],EIF4E3[22,25],EIF4E2[29,29]","mRNA","mRNA","by homology",".",".",".",".",".",".","GO:0003723,GO:0003743,GO:0005845,GO:0006417,GO:0006413","RNA binding,translation initiation factor activity,mRNA cap binding complex,regulation of translation,translational initiation","GO:0003723,GO:0003743,GO:0005737,GO:0005845,GO:0006417,GO:0006413","RNA binding,translation initiation factor activity,cytoplasm,mRNA cap binding complex,regulation of translation,translational initiation","."]
["EIF4E3","eukaryotic translation initiation factor 4E family member 3 [Source:HGNC Symbol;Acc:31837]","ENSG00000163412","ENSP00000374476",1,"IF4E[1]","family-903","EIF4E,EIF4E1B,EIF4E3,EIF4E2","EIF4E","EIF4E1B[56,57],EIF4E3[22,25],EIF4E2[29,29]","mRNA","mRNA","EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).[supplied by OMIM, Mar 2008]",".",".",".",".",".",".","GO:0003723,GO:0003743,GO:0005845,GO:0006417,GO:0006413","RNA binding,translation initiation factor activity,mRNA cap binding complex,regulation of translation,translational initiation","GO:0003723,GO:0003743,GO:0005737,GO:0005829,GO:0005845,GO:0006417,GO:0019221,GO:0006413","RNA binding,translation initiation factor activity,cytoplasm,cytosol,mRNA cap binding complex,regulation of translation,cytokine-mediated signaling pathway,translational initiation","."]
["EIF4E","eukaryotic translation initiation factor 4E [Source:HGNC Symbol;Acc:3287]","ENSG00000151247","ENSP00000425561",2,"IF4E[2]","family-903","EIF4E,EIF4E1B,EIF4E3,EIF4E2","EIF4E","EIF4E1B[56,57],EIF4E3[22,25],EIF4E2[29,29]","mRNA","mRNA","The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]","translationfactor",".",".",1,".",".","GO:0003723,GO:0003743,GO:0000339,GO:0031370,GO:0000932,GO:0005845,GO:0010494,GO:0016281,GO:0006412,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0006406,GO:0006413","RNA binding,translation initiation factor activity,RNA cap binding,eukaryotic initiation factor 4G binding,cytoplasmic mRNA processing body,mRNA cap binding complex,cytoplasmic stress granule,eukaryotic translation initiation factor 4F complex,translation,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,mRNA export from nucleus,translational initiation","GO:0005515,GO:0003723,GO:0003743,GO:0000339,GO:0031370,GO:0043234,GO:0005737,GO:0005829,GO:0000932,GO:0005845,GO:0010494,GO:0033391,GO:0016281,GO:0016442,GO:0006412,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0008286,GO:0019221,GO:0006406,GO:0044267,GO:0030324,GO:0045931,GO:0000082,GO:0019048,GO:0006413","protein binding,RNA binding,translation initiation factor activity,RNA cap binding,eukaryotic initiation factor 4G binding,protein complex,cytoplasm,cytosol,cytoplasmic mRNA processing body,mRNA cap binding complex,cytoplasmic stress granule,chromatoid body,eukaryotic translation initiation factor 4F complex,RISC complex,translation,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,insulin receptor signaling pathway,cytokine-mediated signaling pathway,mRNA export from nucleus,cellular protein metabolic process,lung development,positive regulation of mitotic cell cycle,G1/S transition of mitotic cell cycle,modulation by virus of host morphology or physiology,translational initiation"," AUTISM, SUSCEPTIBILITY TO, 19; AUTS19"]
["BUD13","BUD13 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:28199]","ENSG00000137656","ENSP00000260210",1,"Bud13[1]","family-904","BUD13",".",".","mRNA","mRNA",11884590,".","novel",".",1,".",".","GO:0000398,GO:0006406","mRNA splicing, via spliceosome,mRNA export from nucleus","GO:0005515,GO:0070274,GO:0000398,GO:0006406","protein binding,RES complex,mRNA splicing, via spliceosome,mRNA export from nucleus","."]
["CTU1","cytosolic thiouridylase subunit 1 homolog (S. pombe) [Source:HGNC Symbol;Acc:29590]","ENSG00000142544","ENSP00000390011",1,"ATP_bind_3[1]","family-905","CTU1",".",".","tRNA","tRNA","23874237, 18391219",".",".",".",".",".",".","GO:0000049,GO:0008033,GO:0002098,GO:0034227","tRNA binding,tRNA processing,tRNA wobble uridine modification,tRNA thio-modification","GO:0005515,GO:0005524,GO:0016740,GO:0000049,GO:0005739,GO:0005829,GO:0008033,GO:0002098,GO:0034227","protein binding,ATP binding,transferase activity,tRNA binding,mitochondrion,cytosol,tRNA processing,tRNA wobble uridine modification,tRNA thio-modification","."]
["GTPBP1","GTP binding protein 1 [Source:HGNC Symbol;Acc:4669]","ENSG00000100226","ENSP00000216044",3,"GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-906","GTPBP1,GTPBP2","GTPBP1","GTPBP2[40,44]","mRNA","putative mRNA",21515746,".","novel",".",1,".",".","GO:0000177,GO:0061014","cytoplasmic exosome (RNase complex),positive regulation of mRNA catabolic process","GO:0005525,GO:0003924,GO:0005829,GO:0000177,GO:0061014,GO:0006184,GO:0006955,GO:0007165","GTP binding,GTPase activity,cytosol,cytoplasmic exosome (RNase complex),positive regulation of mRNA catabolic process,GTP catabolic process,immune response,signal transduction","."]
["GTPBP2","GTP binding protein 2 [Source:HGNC Symbol;Acc:4670]","ENSG00000172432","ENSP00000304893",3,"GTP_EFTU_D2[1],GTP_EFTU_D3[1],GTP_EFTU[1]","family-906","GTPBP1,GTPBP2","GTPBP1","GTPBP2[40,44]","mRNA","putative mRNA",21515746,".",".",".",".",".",".",".",".","GO:0005515,GO:0005525,GO:0003924","protein binding,GTP binding,GTPase activity","."]
["MTERFD2","MTERF domain containing 2 [Source:HGNC Symbol;Acc:28785]","ENSG00000122085","ENSP00000375840",1,"mTERF[1]","family-907","MTERFD2",".",".","rRNA","rRNA",22949673,".",".",".",".",".",".","GO:0042255,GO:0019843,GO:0005762,GO:0006364","ribosome assembly,rRNA binding,mitochondrial large ribosomal subunit,rRNA processing","GO:0005739,GO:0007507,GO:0043010,GO:0006626,GO:0006390,GO:0042255,GO:0005515,GO:0019843,GO:0005762,GO:0006364","mitochondrion,heart development,camera-type eye development,protein targeting to mitochondrion,transcription from mitochondrial promoter,ribosome assembly,protein binding,rRNA binding,mitochondrial large ribosomal subunit,rRNA processing","."]
["SRPR","signal recognition particle receptor (docking protein) [Source:HGNC Symbol;Acc:11307]","ENSG00000182934","ENSP00000435508",3,"SRP-alpha_N[1],SRP54[1],SRP54_N[1]","family-908","SRPR",".",".","ncRNA","7SL","established RBP ",".","novel",".",1,".",".","GO:0006412","translation","GO:0000166,GO:0005525,GO:0003924,GO:0017111,GO:0005047,GO:0016021,GO:0005789,GO:0016020,GO:0005783,GO:0005785,GO:0006412,GO:0006810,GO:0010467,GO:0006886,GO:0006613,GO:0044267,GO:0030968,GO:0006614,GO:0006184,GO:0006987","nucleotide binding,GTP binding,GTPase activity,nucleoside-triphosphatase activity,signal recognition particle binding,integral to membrane,endoplasmic reticulum membrane,membrane,endoplasmic reticulum,signal recognition particle receptor complex,translation,transport,gene expression,intracellular protein transport,cotranslational protein targeting to membrane,cellular protein metabolic process,endoplasmic reticulum unfolded protein response,SRP-dependent cotranslational protein targeting to membrane,GTP catabolic process,activation of signaling protein activity involved in unfolded protein response","."]
["DDX50","DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 [Source:HGNC Symbol;Acc:17906]","ENSG00000107625","ENSP00000362687",3,"Helicase_C[1],DEAD[1],GUCT[1]","family-909","DDX21,DDX50","DDX21","DDX50[54,58]","rRNA","putative rRNA","This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008]","helicase","RNAbinding",1,1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0005524,GO:0003676,GO:0003677,GO:0008026,GO:0016787,GO:0004386,GO:0005634,GO:0005886,GO:0005730","RNA binding,ATP binding,nucleic acid binding,DNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,nucleus,plasma membrane,nucleolus","."]
["DDX21","DEAD (Asp-Glu-Ala-Asp) box helicase 21 [Source:HGNC Symbol;Acc:2744]","ENSG00000165732","ENSP00000346120",3,"Helicase_C[1],DEAD[1],GUCT[1]","family-909","DDX21,DDX50","DDX21","DDX50[54,58]","rRNA","rRNA","This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]","helicase","RNAbinding",1,1,1,".","GO:0003723,GO:0003725,GO:0004004,GO:0043330","RNA binding,double-stranded RNA binding,ATP-dependent RNA helicase activity,response to exogenous dsRNA","GO:0005515,GO:0003723,GO:0005524,GO:0003676,GO:0003677,GO:0003725,GO:0008026,GO:0016787,GO:0004386,GO:0004004,GO:0005634,GO:0005730,GO:0009615,GO:0043330","protein binding,RNA binding,ATP binding,nucleic acid binding,DNA binding,double-stranded RNA binding,ATP-dependent helicase activity,hydrolase activity,helicase activity,ATP-dependent RNA helicase activity,nucleus,nucleolus,response to virus,response to exogenous dsRNA","."]
["ZCRB1","zinc finger CCHC-type and RNA binding motif 1 [Source:HGNC Symbol;Acc:29620]","ENSG00000139168","ENSP00000266529",2,"RRM_1[1],zf-CCHC[1]","family-91","ZCRB1",".",".","snRNA","snRNA/mRNA","It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing. ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0005689,GO:0006397,GO:0008380","RNA binding,U12-type spliceosomal complex,mRNA processing,RNA splicing","GO:0000166,GO:0008270,GO:0003676,GO:0003723,GO:0005654,GO:0005689,GO:0006397,GO:0008380","nucleotide binding,zinc ion binding,nucleic acid binding,RNA binding,nucleoplasm,U12-type spliceosomal complex,mRNA processing,RNA splicing","."]
["RPL13A","ribosomal protein L13a [Source:HGNC Symbol;Acc:10304]","ENSG00000142541","ENSP00000375730",1,"Ribosomal_L13[1]","family-910","RPL13A",".",".","ribosome","ribosome","established RBP ",".","RNArelated",".",1,1,".","GO:0003735,GO:0005840,GO:0015934,GO:0006412,GO:0030529,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,large ribosomal subunit,translation,ribonucleoprotein complex,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0015934,GO:0006412,GO:0005829,GO:0030529,GO:0022625,GO:0097452,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0071346,GO:0044267,GO:0017148,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:1901194","structural constituent of ribosome,ribosome,large ribosomal subunit,translation,cytosol,ribonucleoprotein complex,cytosolic large ribosomal subunit,GAIT complex,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular response to interferon-gamma,cellular protein metabolic process,negative regulation of translation,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,negative regulation of formation of translation preinitiation complex","."]
["SRA1","steroid receptor RNA activator 1 [Source:HGNC Symbol;Acc:11281]","ENSG00000213523","ENSP00000473378",1,"SRA1[1]","family-911","SRA1",".",".","ncRNA","lincRNA","Function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases",".",".",".",".",".",".","GO:0030529","ribonucleoprotein complex","GO:0030374,GO:0005515,GO:0003677,GO:0003713,GO:0010861,GO:0005634,GO:0005667,GO:0005737,GO:0030529,GO:0031252,GO:0006351,GO:0008283,GO:0045944,GO:0030154,GO:0097194,GO:2000273","ligand-dependent nuclear receptor transcription coactivator activity,protein binding,DNA binding,transcription coactivator activity,thyroid hormone receptor activator activity,nucleus,transcription factor complex,cytoplasm,ribonucleoprotein complex,cell leading edge,transcription, DNA-templated,cell proliferation,positive regulation of transcription from RNA polymerase II promoter,cell differentiation,execution phase of apoptosis,positive regulation of receptor activity","."]
["PAPOLB","poly(A) polymerase beta (testis specific) [Source:HGNC Symbol;Acc:15970]","ENSG00000218823","ENSP00000384700",2,"PAP_RNA-bind[1],PAP_central[1]","family-912","PAPOLA,PAPOLB,PAPOLG","PAPOLA","PAPOLB[72,85],PAPOLG[59,60]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000398,GO:0043631,GO:0006378,GO:0031123","RNA binding,mRNA splicing, via spliceosome,RNA polyadenylation,mRNA polyadenylation,RNA 3'-end processing","GO:0005515,GO:0003723,GO:0005524,GO:0046872,GO:0016779,GO:0004652,GO:0005737,GO:0005634,GO:0005783,GO:0000398,GO:0043631,GO:0006378,GO:0006369,GO:0031123","protein binding,RNA binding,ATP binding,metal ion binding,nucleotidyltransferase activity,polynucleotide adenylyltransferase activity,cytoplasm,nucleus,endoplasmic reticulum,mRNA splicing, via spliceosome,RNA polyadenylation,mRNA polyadenylation,termination of RNA polymerase II transcription,RNA 3'-end processing","."]
["PAPOLG","poly(A) polymerase gamma [Source:HGNC Symbol;Acc:14982]","ENSG00000115421","ENSP00000238714",2,"PAP_RNA-bind[1],PAP_central[1]","family-912","PAPOLA,PAPOLB,PAPOLG","PAPOLA","PAPOLB[72,85],PAPOLG[59,60]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0043631,GO:0031123,GO:0006378","RNA binding,RNA polyadenylation,RNA 3'-end processing,mRNA polyadenylation","GO:0003723,GO:0016779,GO:0004652,GO:0005634,GO:0043631,GO:0031123,GO:0005524,GO:0046872,GO:0006378","RNA binding,nucleotidyltransferase activity,polynucleotide adenylyltransferase activity,nucleus,RNA polyadenylation,RNA 3'-end processing,ATP binding,metal ion binding,mRNA polyadenylation","."]
["PAPOLA","poly(A) polymerase alpha [Source:HGNC Symbol;Acc:14981]","ENSG00000090060","ENSP00000450534",2,"PAP_RNA-bind[1],PAP_central[1]","family-912","PAPOLA,PAPOLB,PAPOLG","PAPOLA","PAPOLB[72,85],PAPOLG[59,60]","mRNA","mRNA","The protein encoded by this gene belongs to the poly(A) polymerase family. It is required for the addition of adenosine residues for the creation of the 3'-poly(A) tail of mRNAs. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]",".",".",".",".",".",".","GO:0043631,GO:0003723,GO:0031123,GO:0008380,GO:0000398,GO:0031124,GO:0006378","RNA polyadenylation,RNA binding,RNA 3'-end processing,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,mRNA polyadenylation","GO:0004652,GO:0043631,GO:0003723,GO:0016779,GO:0005634,GO:0031123,GO:0005524,GO:0000287,GO:0030145,GO:0005737,GO:0005654,GO:0006366,GO:0010467,GO:0008380,GO:0000398,GO:0031124,GO:0006378,GO:0006369","polynucleotide adenylyltransferase activity,RNA polyadenylation,RNA binding,nucleotidyltransferase activity,nucleus,RNA 3'-end processing,ATP binding,magnesium ion binding,manganese ion binding,cytoplasm,nucleoplasm,transcription from RNA polymerase II promoter,gene expression,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,mRNA polyadenylation,termination of RNA polymerase II transcription","."]
["RPL41","ribosomal protein L41 [Source:HGNC Symbol;Acc:10354]","ENSG00000229117","ENSP00000420821",1,"Ribosomal_L41[1]","family-913","RPL41",".",".","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005829,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytosol,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["ZNF768","zinc finger protein 768 [Source:HGNC Symbol;Acc:26273]","ENSG00000169957","ENSP00000369777",8,"zf-H2C2_2[7],zf-C2H2[1]","family-914","ZNF768",".",".","unknown","unknown","established RBP ","candidate mRNA binder",".",".",1,".",".",".",".","GO:0046872,GO:0003677,GO:0005665,GO:0006366,GO:0006355","metal ion binding,DNA binding,DNA-directed RNA polymerase II, core complex,transcription from RNA polymerase II promoter,regulation of transcription, DNA-dependent","."]
["SCAF1","SR-related CTD-associated factor 1 [Source:HGNC Symbol;Acc:30403] [Type: protein coding Ensembl/Havana merge]","ENSG00000126461","ENSP00000353769",".",".","family-915","SCAF1",".",".","mRNA","putative mRNA",11461075,".",".",".",".",".",".","GO:0006397,GO:0003723,GO:0008380","mRNA processing,RNA binding,RNA splicing","GO:0019904,GO:0006366,GO:0006397,GO:0003723,GO:0005634,GO:0008380","protein domain specific binding,transcription from RNA polymerase II promoter,mRNA processing,RNA binding,nucleus,RNA splicing","."]
["MRPS15","mitochondrial ribosomal protein S15 [Source:HGNC Symbol;Acc:14504]","ENSG00000116898","ENSP00000362208",1,"Ribosomal_S15[1]","family-916","MRPS15",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0003735,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005739,GO:0005622,GO:0005840,GO:0031965,GO:0005763,GO:0006412","structural constituent of ribosome,mitochondrion,intracellular,ribosome,nuclear membrane,mitochondrial small ribosomal subunit,translation","."]
["RNASET2","ribonuclease T2 [Source:HGNC Symbol;Acc:21686]","ENSG00000026297","ENSP00000426455",1,"Ribonuclease_T2[1]","family-917","RNASET2",".",".","diverse","diverse","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0033897,GO:0004540,GO:0006401","RNA binding,ribonuclease T2 activity,ribonuclease activity,RNA catabolic process","GO:0003723,GO:0033897,GO:0004540,GO:0005576,GO:0005615,GO:0005764,GO:0005788,GO:0043202,GO:0006401","RNA binding,ribonuclease T2 activity,ribonuclease activity,extracellular region,extracellular space,lysosome,endoplasmic reticulum lumen,lysosomal lumen,RNA catabolic process"," LEUKOENCEPHALOPATHY, CYSTIC, WITHOUT MEGALENCEPHALY"]
["EIF2B1","eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa [Source:HGNC Symbol;Acc:3257]","ENSG00000111361","ENSP00000443172",1,"IF-2B[1]","family-918","EIF2B1",".",".","mRNA","putative mRNA","eiF2B complex",".",".",".",".",".",".","GO:0003743,GO:0005851,GO:0006417,GO:0006412,GO:0006446,GO:0006413","translation initiation factor activity,eukaryotic translation initiation factor 2B complex,regulation of translation,translation,regulation of translational initiation,translational initiation","GO:0003743,GO:0044237,GO:0005515,GO:0005525,GO:0005085,GO:0030234,GO:0019003,GO:0005886,GO:0005737,GO:0016020,GO:0005829,GO:0005851,GO:0006417,GO:0006412,GO:0009749,GO:0009408,GO:0050790,GO:0043434,GO:0014003,GO:0010467,GO:0006446,GO:0044267,GO:0032057,GO:0006413,GO:0051716","translation initiation factor activity,cellular metabolic process,protein binding,GTP binding,guanyl-nucleotide exchange factor activity,enzyme regulator activity,GDP binding,plasma membrane,cytoplasm,membrane,cytosol,eukaryotic translation initiation factor 2B complex,regulation of translation,translation,response to glucose,response to heat,regulation of catalytic activity,response to peptide hormone,oligodendrocyte development,gene expression,regulation of translational initiation,cellular protein metabolic process,negative regulation of translational initiation in response to stress,translational initiation,cellular response to stimulus"," LEUKOENCEPHALOPATHY WITH VANISHING WHITE MATTER; VWM"]
["RPL36A","ribosomal protein L36a [Source:HGNC Symbol;Acc:10359]","ENSG00000269315","ENSP00000470206",1,"Ribosomal_L44[1]","family-919","RPL36A,RPL36AL","RPL36A","RPL36AL[74,99]","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0022625,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,cytosolic large ribosomal subunit,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005737,GO:0005829,GO:0005622,GO:0005840,GO:0022625,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,cytoplasm,cytosol,intracellular,ribosome,cytosolic large ribosomal subunit,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["RPL36AL","ribosomal protein L36a-like [Source:HGNC Symbol;Acc:10346]","ENSG00000165502","ENSP00000346012",1,"Ribosomal_L44[1]","family-919","RPL36A,RPL36AL","RPL36A","RPL36AL[74,99]","ribosome","ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412","structural constituent of ribosome,ribosome,translation","GO:0003735,GO:0005622,GO:0005840,GO:0006412","structural constituent of ribosome,intracellular,ribosome,translation","."]
["DDX26B","DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B [Source:HGNC Symbol;Acc:27334]","ENSG00000165359","ENSP00000359788",2,"VWA_2[1],INT_SG_DDX_CT_C[1]","family-92","DDX26B,INTS6","DDX26B","INTS6[66,64]","mRNA","mRNA","by homology",".",".",".",".",".",".",".",".",".",".","."]
["INTS6","integrator complex subunit 6 [Source:HGNC Symbol;Acc:14879]","ENSG00000102786","ENSP00000310260",2,"VWA_2[1],INT_SG_DDX_CT_C[1]","family-92","DDX26B,INTS6","DDX26B","INTS6[66,64]","snRNA","snRNA","DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0032039,GO:0016180","integrator complex,snRNA processing","GO:0005515,GO:0004888,GO:0005634,GO:0015629,GO:0032039,GO:0016180","protein binding,transmembrane signaling receptor activity,nucleus,actin cytoskeleton,integrator complex,snRNA processing","."]
["RPS7","ribosomal protein S7 [Source:HGNC Symbol;Acc:10440]","ENSG00000171863","ENSP00000385018",1,"Ribosomal_S7e[1]","family-920","RPS7",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0003735,GO:0022627,GO:0005840,GO:0030529,GO:0030686,GO:0006412,GO:0016070,GO:0016071,GO:0006364,GO:0006414,GO:0006413,GO:0000184,GO:0006415,GO:0042274","RNA binding,structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,ribonucleoprotein complex,90S preribosome,translation,RNA metabolic process,mRNA metabolic process,rRNA processing,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,ribosomal small subunit biogenesis","GO:0003723,GO:0005515,GO:0003735,GO:0005634,GO:0005829,GO:0005622,GO:0005730,GO:0022627,GO:0005840,GO:0030529,GO:0005815,GO:0032040,GO:0030686,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083,GO:0042274","RNA binding,protein binding,structural constituent of ribosome,nucleus,cytosol,intracellular,nucleolus,cytosolic small ribosomal subunit,ribosome,ribonucleoprotein complex,microtubule organizing center,small-subunit processome,90S preribosome,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription,ribosomal small subunit biogenesis"," DIAMOND-BLACKFAN ANEMIA 8; DBA8"]
["RRNAD1","ribosomal RNA adenine dimethylase domain containing 1 [Source:HGNC Symbol;Acc:24273]","ENSG00000143303","ENSP00000357199",1,"Methyltransf_32[1]","family-921","METTL25,RRNAD1","METTL25","RRNAD1[21,26]","unknown","unknown","by domain",".",".",".",".",".",".","GO:0000179","rRNA (adenine-N6,N6-)-dimethyltransferase activity","GO:0000179,GO:0016021","rRNA (adenine-N6,N6-)-dimethyltransferase activity,integral to membrane","."]
["MRPS21","mitochondrial ribosomal protein S21 [Source:HGNC Symbol;Acc:14046]","ENSG00000187145","ENSP00000358080",1,"Ribosomal_S21[1]","family-922","MRPS21",".",".","ribosome","mitochondrial ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,ribosome,mitochondrial small ribosomal subunit,translation","GO:0003735,GO:0005622,GO:0005840,GO:0005763,GO:0006412","structural constituent of ribosome,intracellular,ribosome,mitochondrial small ribosomal subunit,translation","."]
["SETD7","SET domain containing (lysine methyltransferase) 7 [Source:HGNC Symbol;Acc:30412]","ENSG00000145391","ENSP00000274031",4,"SET[1],MORN[3]","family-923","SETD7",".",".","ncRNA","viral RNA",20227666,".",".",".",".",".",".",".",".","GO:0005515,GO:0018024,GO:0002039,GO:0016279,GO:0005634,GO:0005694,GO:0006351,GO:0006355,GO:0016568,GO:0018027,GO:0034968,GO:0018026","protein binding,histone-lysine N-methyltransferase activity,p53 binding,protein-lysine N-methyltransferase activity,nucleus,chromosome,transcription, DNA-templated,regulation of transcription, DNA-dependent,chromatin modification,peptidyl-lysine dimethylation,histone lysine methylation,peptidyl-lysine monomethylation","."]
["RBM8A","RNA binding motif protein 8A [Source:HGNC Symbol;Acc:9905]","ENSG00000131795","ENSP00000333001",1,"RRM_1[1]","family-924","RBM8A",".",".","mRNA","mRNA","This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0003729,GO:0071013,GO:0016070,GO:0016071,GO:0006417,GO:0008380,GO:0000381,GO:0000398,GO:0006406,GO:0031124,GO:0000184","RNA binding,mRNA binding,catalytic step 2 spliceosome,RNA metabolic process,mRNA metabolic process,regulation of translation,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0000166,GO:0003723,GO:0005515,GO:0003676,GO:0003729,GO:0005634,GO:0005737,GO:0005829,GO:0005654,GO:0016607,GO:0035145,GO:0071013,GO:0006366,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0008380,GO:0000381,GO:0000398,GO:0006406,GO:0031124,GO:0000184,GO:0006369","nucleotide binding,RNA binding,protein binding,nucleic acid binding,mRNA binding,nucleus,cytoplasm,cytosol,nucleoplasm,nuclear speck,exon-exon junction complex,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription","."]
["MAGOH","mago-nashi homolog, proliferation-associated (Drosophila) [Source:HGNC Symbol;Acc:6815]","ENSG00000162385","ENSP00000360525",1,"Mago_nashi[1]","family-925","MAGOH,MAGOHB","MAGOH","MAGOHB[98,97]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0003723,GO:0071013,GO:0016070,GO:0016071,GO:0006417,GO:0008380,GO:0000381,GO:0000398,GO:0006406,GO:0031124,GO:0000184","RNA binding,catalytic step 2 spliceosome,RNA metabolic process,mRNA metabolic process,regulation of translation,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005634,GO:0003723,GO:0005515,GO:0005829,GO:0005654,GO:0016607,GO:0035145,GO:0071013,GO:0006366,GO:0010467,GO:0016070,GO:0016071,GO:0006417,GO:0008380,GO:0000381,GO:0000398,GO:0006406,GO:0031124,GO:0000184,GO:0006369","nucleus,RNA binding,protein binding,cytosol,nucleoplasm,nuclear speck,exon-exon junction complex,catalytic step 2 spliceosome,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,mRNA metabolic process,regulation of translation,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,mRNA splicing, via spliceosome,mRNA export from nucleus,mRNA 3'-end processing,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,termination of RNA polymerase II transcription","."]
["MAGOHB","mago-nashi homolog B (Drosophila) [Source:HGNC Symbol;Acc:25504]","ENSG00000111196","ENSP00000371305",1,"Mago_nashi[1]","family-925","MAGOH,MAGOHB","MAGOH","MAGOHB[98,97]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",".","GO:0003723,GO:0006397,GO:0008380,GO:0051028","RNA binding,mRNA processing,RNA splicing,mRNA transport","GO:0005634,GO:0003723,GO:0006397,GO:0008380,GO:0051028","nucleus,RNA binding,mRNA processing,RNA splicing,mRNA transport","."]
["RPL37A","ribosomal protein L37a [Source:HGNC Symbol;Acc:10348]","ENSG00000197756","ENSP00000470348",1,"Ribosomal_L37ae[1]","family-926","RPL37A",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0046872,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,metal ion binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["NOLC1","nucleolar and coiled-body phosphoprotein 1 [Source:HGNC Symbol;Acc:15608]","ENSG00000166197","ENSP00000359024",1,"SRP40_C[1]","family-927","NOLC1",".",".","snoRNA","snoRNA",19129172,"RNAbinding","RNAbinding",1,1,1,".","GO:0006364","rRNA processing","GO:0015030,GO:0007000,GO:0005515,GO:0005524,GO:0005525,GO:0005737,GO:0005730,GO:0007067,GO:0007049,GO:0006364,GO:0005654","Cajal body,nucleolus organization,protein binding,ATP binding,GTP binding,cytoplasm,nucleolus,mitosis,cell cycle,rRNA processing,nucleoplasm","."]
["IARS2","isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:29685]","ENSG00000067704","ENSP00000303279",3,"zf-FPG_IleRS[1],Anticodon_1[1],tRNA-synt_1[1]","family-928","IARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0002161,GO:0004812,GO:0004822,GO:0006418,GO:0006428","aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,isoleucine-tRNA ligase activity,tRNA aminoacylation for protein translation,isoleucyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0003824,GO:0002161,GO:0004812,GO:0004822,GO:0005739,GO:0005737,GO:0005759,GO:0010467,GO:0006418,GO:0006428","nucleotide binding,ATP binding,catalytic activity,aminoacyl-tRNA editing activity,aminoacyl-tRNA ligase activity,isoleucine-tRNA ligase activity,mitochondrion,cytoplasm,mitochondrial matrix,gene expression,tRNA aminoacylation for protein translation,isoleucyl-tRNA aminoacylation","."]
["LSM1","LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:20472]","ENSG00000175324","ENSP00000310596",1,"LSM[1]","family-929","LSM1",".",".","snRNA","snRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0030529,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0000375,GO:0043928,GO:0071044","RNA binding,ribonucleoprotein complex,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process","GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0030529,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0000375,GO:0043928,GO:0071044","RNA binding,protein binding,nucleus,cytoplasm,cytosol,ribonucleoprotein complex,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,RNA splicing, via transesterification reactions,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,histone mRNA catabolic process","."]
["SUPT4H1","suppressor of Ty 4 homolog 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:11467]","ENSG00000213246","ENSP00000462100",1,"Spt4[1]","family-93","SUPT4H1",".",".","mRNA","mRNA","This gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]",".",".",".",".",".",".",".",".","GO:0003700,GO:0005515,GO:0008270,GO:0046982,GO:0005634,GO:0005654,GO:0032044,GO:0000122,GO:0045944,GO:0006366,GO:0034244,GO:0006355,GO:0016032,GO:0010467,GO:0006357,GO:0006368,GO:0006338,GO:0032786,GO:0032785,GO:0050434,GO:0006351","sequence-specific DNA binding transcription factor activity,protein binding,zinc ion binding,protein heterodimerization activity,nucleus,nucleoplasm,DSIF complex,negative regulation of transcription from RNA polymerase II promoter,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,negative regulation of transcription elongation from RNA polymerase II promoter,regulation of transcription, DNA-dependent,viral process,gene expression,regulation of transcription from RNA polymerase II promoter,transcription elongation from RNA polymerase II promoter,chromatin remodeling,positive regulation of DNA-dependent transcription, elongation,negative regulation of DNA-dependent transcription, elongation,positive regulation of viral transcription,transcription, DNA-templated","."]
["EXO1","exonuclease 1 [Source:HGNC Symbol;Acc:3511]","ENSG00000174371","ENSP00000355506",2,"XPG_N[1],XPG_I[1]","family-930","EXO1",".",".","diverse","RNA/DNA","RNase H activity",".",".",".",".",".",".","GO:0004527,GO:0008409,GO:0004523","exonuclease activity,5'-3' exonuclease activity,ribonuclease H activity","GO:0005515,GO:0004527,GO:0046872,GO:0003677,GO:0003824,GO:0004518,GO:0008409,GO:0048256,GO:0004523,GO:0043566,GO:0045145,GO:0035312,GO:0051908,GO:0005634,GO:0006298,GO:0016446,GO:0006281,GO:0006310,GO:0007126,GO:0045190,GO:0002455","protein binding,exonuclease activity,metal ion binding,DNA binding,catalytic activity,nuclease activity,5'-3' exonuclease activity,flap endonuclease activity,ribonuclease H activity,structure-specific DNA binding,single-stranded DNA 5'-3' exodeoxyribonuclease activity,5'-3' exodeoxyribonuclease activity,double-stranded DNA 5'-3' exodeoxyribonuclease activity,nucleus,mismatch repair,somatic hypermutation of immunoglobulin genes,DNA repair,DNA recombination,meiosis,isotype switching,humoral immune response mediated by circulating immunoglobulin","."]
["DCP1B","DCP1 decapping enzyme homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:24451]","ENSG00000151065","ENSP00000280665",1,"DCP1[1]","family-931","DCP1A,DCP1B","DCP1A","DCP1B[28,26]","mRNA","mRNA","DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).[supplied by OMIM, Mar 2008]",".",".",".",".",".",".","GO:0016070,GO:0016071,GO:0000288,GO:0043928,GO:0000184","RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0005737,GO:0043231,GO:0005515,GO:0016787,GO:0005634,GO:0005829,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0043928,GO:0000184","cytoplasm,intracellular membrane-bounded organelle,protein binding,hydrolase activity,nucleus,cytosol,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["DCP1A","decapping mRNA 1A [Source:HGNC Symbol;Acc:18714]","ENSG00000162290","ENSP00000475920",1,"DCP1[1]","family-931","DCP1A,DCP1B","DCP1A","DCP1B[28,26]","mRNA","mRNA","Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]",".",".",".",".",".",".","GO:0000932","cytoplasmic mRNA processing body","GO:0000932","cytoplasmic mRNA processing body","."]
["DNAJC17","DnaJ (Hsp40) homolog, subfamily C, member 17 [Source:HGNC Symbol;Acc:25556]","ENSG00000104129","ENSP00000220496",2,"RRM_5[1],DnaJ[1]","family-932","DNAJC12,DNAJC17","DNAJC12","DNAJC17[22,14]","unknown","unknown","by domain",".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003723,GO:0003676","nucleotide binding,RNA binding,nucleic acid binding","."]
["RNGTT","RNA guanylyltransferase and 5'-phosphatase [Source:HGNC Symbol;Acc:10073]","ENSG00000111880","ENSP00000442609",3,"mRNA_cap_C[1],mRNA_cap_enzyme[1],DSPc[1]","family-933","DUSP11,RNGTT","DUSP11","RNGTT[22,14]","mRNA","mRNA",21636784,".",".",".",".",".",".","GO:0004484,GO:0006397,GO:0006370,GO:0006396","mRNA guanylyltransferase activity,mRNA processing,7-methylguanosine mRNA capping,RNA processing","GO:0004725,GO:0008138,GO:0016791,GO:0004484,GO:0004651,GO:0005634,GO:0006397,GO:0006470,GO:0006370,GO:0016311,GO:0005525,GO:0005654,GO:0006366,GO:0016032,GO:0010467,GO:0006396,GO:0019048","protein tyrosine phosphatase activity,protein tyrosine/serine/threonine phosphatase activity,phosphatase activity,mRNA guanylyltransferase activity,polynucleotide 5'-phosphatase activity,nucleus,mRNA processing,protein dephosphorylation,7-methylguanosine mRNA capping,dephosphorylation,GTP binding,nucleoplasm,transcription from RNA polymerase II promoter,viral process,gene expression,RNA processing,modulation by virus of host morphology or physiology","."]
["DUSP11","dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) [Source:HGNC Symbol;Acc:3066]","ENSG00000144048","ENSP00000272444",1,"DSPc[1]","family-933","DUSP11,RNGTT","DUSP11","RNGTT[22,14]","mRNA","putative mRNA","This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008]","RNAbinding","RNAbinding",1,1,".",".","GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0004725,GO:0008138,GO:0016791,GO:0006470,GO:0016311,GO:0003723,GO:0005634,GO:0006396,GO:0035335","protein tyrosine phosphatase activity,protein tyrosine/serine/threonine phosphatase activity,phosphatase activity,protein dephosphorylation,dephosphorylation,RNA binding,nucleus,RNA processing,peptidyl-tyrosine dephosphorylation","."]
["CHERP","calcium homeostasis endoplasmic reticulum protein [Source:HGNC Symbol;Acc:16930]","ENSG00000085872","ENSP00000439856",3,"G-patch[1],Surp[1],CTD_bind[1]","family-934","CHERP",".",".","mRNA","mRNA",24078636,"RNAbinding","RNAbinding",1,1,".",1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0003723,GO:0003676,GO:0006396,GO:0005515,GO:0044325,GO:0033017,GO:0005737,GO:0048471,GO:0008285,GO:0007399,GO:0051209,GO:0006874,GO:0051533","RNA binding,nucleic acid binding,RNA processing,protein binding,ion channel binding,sarcoplasmic reticulum membrane,cytoplasm,perinuclear region of cytoplasm,negative regulation of cell proliferation,nervous system development,release of sequestered calcium ion into cytosol,cellular calcium ion homeostasis,positive regulation of NFAT protein import into nucleus","."]
["WDR61","WD repeat domain 61 [Source:HGNC Symbol;Acc:30300] ","ENSG00000140395","ENSP00000267973",6,"WD40[6]","family-935","AAMP,WDR61","AAMP","WDR61[17,24]","mRNA","putative mRNA",16024656,".",".",".",".",".",".","GO:0055087","Ski complex","GO:0005515,GO:0005634,GO:0005737,GO:0035327,GO:0016593,GO:0055087,GO:0006351,GO:0045944,GO:0016055,GO:0051571,GO:0080182,GO:0032968,GO:0045638,GO:2001162","protein binding,nucleus,cytoplasm,transcriptionally active chromatin,Cdc73/Paf1 complex,Ski complex,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,Wnt signaling pathway,positive regulation of histone H3-K4 methylation,histone H3-K4 trimethylation,positive regulation of transcription elongation from RNA polymerase II promoter,negative regulation of myeloid cell differentiation,positive regulation of histone H3-K79 methylation","."]
["NANOS1","nanos homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:23044]","ENSG00000188613","ENSP00000345924",1,"zf-nanos[1]","family-936","NANOS1,NANOS2,NANOS3","NANOS1","NANOS2[15,32],NANOS3[16,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0030371","RNA binding,translation repressor activity","GO:0003723,GO:0005515,GO:0008270,GO:0030371,GO:0005737,GO:0048471,GO:0016477,GO:0017148,GO:0010631","RNA binding,protein binding,zinc ion binding,translation repressor activity,cytoplasm,perinuclear region of cytoplasm,cell migration,negative regulation of translation,epithelial cell migration","."]
["NANOS2","nanos homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:23292]","ENSG00000188425","ENSP00000341021",1,"zf-nanos[1]","family-936","NANOS1,NANOS2,NANOS3","NANOS1","NANOS2[15,32],NANOS3[16,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0006402,GO:0006417","RNA binding,cytoplasmic mRNA processing body,mRNA catabolic process,regulation of translation","GO:0005515,GO:0003723,GO:0008270,GO:0005737,GO:0000932,GO:0048471,GO:0007283,GO:0030718,GO:0045835,GO:0006402,GO:0007275,GO:0006417","protein binding,RNA binding,zinc ion binding,cytoplasm,cytoplasmic mRNA processing body,perinuclear region of cytoplasm,spermatogenesis,germ-line stem cell maintenance,negative regulation of meiosis,mRNA catabolic process,multicellular organismal development,regulation of translation","."]
["NANOS3","nanos homolog 3 (Drosophila) [Source:HGNC Symbol;Acc:22048]","ENSG00000187556","ENSP00000341992",1,"zf-nanos[1]","family-936","NANOS1,NANOS2,NANOS3","NANOS1","NANOS2[15,32],NANOS3[16,24]","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0003723,GO:0000932,GO:0010494,GO:0006417","RNA binding,cytoplasmic mRNA processing body,cytoplasmic stress granule,regulation of translation","GO:0003723,GO:0008270,GO:0005634,GO:0005737,GO:0000932,GO:0010494,GO:0007275,GO:0043066,GO:0007283,GO:0006417,GO:0051726,GO:0048477,GO:0007281,GO:0005515,GO:2001234","RNA binding,zinc ion binding,nucleus,cytoplasm,cytoplasmic mRNA processing body,cytoplasmic stress granule,multicellular organismal development,negative regulation of apoptotic process,spermatogenesis,regulation of translation,regulation of cell cycle,oogenesis,germ cell development,protein binding,negative regulation of apoptotic signaling pathway","."]
["EBNA1BP2","EBNA1 binding protein 2 [Source:HGNC Symbol;Acc:15531]","ENSG00000117395","ENSP00000236051",1,"Ebp2[1]","family-937","EBNA1BP2",".",".","rRNA","rRNA",19170763,"candidate mRNA binder","novel",1,1,1,".","GO:0042254","ribosome biogenesis","GO:0005634,GO:0016020,GO:0005730,GO:0042254","nucleus,membrane,nucleolus,ribosome biogenesis","."]
["HELZ","helicase with zinc finger [Source:HGNC Symbol;Acc:16878]","ENSG00000198265","ENSP00000464512",5,"PAM2[1],AAA_19[1],AAA_11[1],zf-CCCH[1],AAA_12[1]","family-938","HELZ",".",".","mRNA","mRNA",21765940,"helicase","novel",1,1,".",1,".",".","GO:0046872,GO:0005524,GO:0005515,GO:0004386,GO:0005634","metal ion binding,ATP binding,protein binding,helicase activity,nucleus","."]
["RNMTL1","RNA methyltransferase like 1 [Source:HGNC Symbol;Acc:18485]","ENSG00000171861","ENSP00000306080",2,"SpoU_methylase[1],SpoU_sub_bind[1]","family-939","RNMTL1",".",".","rRNA","putative rRNA/mRNA",24036117,"RNAbinding","RNAbinding",1,1,".",".","GO:0003723,GO:0008173,GO:0006396","RNA binding,RNA methyltransferase activity,RNA processing","GO:0003723,GO:0008168,GO:0008173,GO:0006396,GO:0005739","RNA binding,methyltransferase activity,RNA methyltransferase activity,RNA processing,mitochondrion","."]
["PDCD4","programmed cell death 4 (neoplastic transformation inhibitor) [Source:HGNC Symbol;Acc:8763]","ENSG00000150593","ENSP00000280154",2,"MA3[2]","family-94","PDCD4",".",".","mRNA","putative mRNA",24681950,".",".",".",".",".",".","GO:0003723","RNA binding","GO:0005488,GO:0003723,GO:0005515,GO:0005634,GO:0005737,GO:0005829,GO:0006915,GO:0045892,GO:0045786,GO:0007569,GO:0043508","binding,RNA binding,protein binding,nucleus,cytoplasm,cytosol,apoptotic process,negative regulation of transcription, DNA-dependent,negative regulation of cell cycle,cell aging,negative regulation of JUN kinase activity","."]
["PTRH2","peptidyl-tRNA hydrolase 2 [Source:HGNC Symbol;Acc:24265]","ENSG00000141378","ENSP00000464327",1,"PTH2[1]","family-940","PTRH2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004045","aminoacyl-tRNA hydrolase activity","GO:0005515,GO:0004045,GO:0005739,GO:0005829,GO:0006915,GO:0010629,GO:2000811,GO:2000210","protein binding,aminoacyl-tRNA hydrolase activity,mitochondrion,cytosol,apoptotic process,negative regulation of gene expression,negative regulation of anoikis,positive regulation of anoikis","."]
["SART3","squamous cell carcinoma antigen recognized by T cells 3 [Source:HGNC Symbol;Acc:16860]","ENSG00000075856","ENSP00000228284",3,"Lsm_interact[1],RRM_1[2]","family-941","SART3",".",".","snRNA","snRNA"," It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing. [provided by RefSeq, Jul 2008]","RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0006396","RNA binding,RNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0005737,GO:0043231,GO:0016607,GO:0006396,GO:0005622,GO:0003676","nucleotide binding,RNA binding,protein binding,cytoplasm,intracellular membrane-bounded organelle,nuclear speck,RNA processing,intracellular,nucleic acid binding"," POROKERATOSIS 3, DISSEMINATED SUPERFICIAL ACTINIC TYPE; POROK3"]
["ZC3H10","zinc finger CCCH-type containing 10 [Source:HGNC Symbol;Acc:25893]","ENSG00000135482","ENSP00000257940",2,"zf-CCCH[2]","family-942","ZC3H10",".",".","unknown","unknown","by homology",".","novel",".",1,1,1,".",".","GO:0046872,GO:0005515","metal ion binding,protein binding","."]
["LSM2","LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) [Source:HGNC Symbol;Acc:13940]","ENSG00000224979","ENSP00000414006",1,"LSM[1]","family-943","LSM2",".",".","snRNA","snRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",1,"GO:0017070,GO:0071013,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0000398,GO:0043928","U6 snRNA binding,catalytic step 2 spliceosome,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","GO:0005515,GO:0019901,GO:0017070,GO:0005634,GO:0005829,GO:0005654,GO:0071013,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0006397,GO:0008380,GO:0000398,GO:0043928","protein binding,protein kinase binding,U6 snRNA binding,nucleus,cytosol,nucleoplasm,catalytic step 2 spliceosome,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay","."]
["MRPS25","mitochondrial ribosomal protein S25 [Source:HGNC Symbol;Acc:14511]","ENSG00000131368","ENSP00000253686",1,"L51_S25_CI-B8[1]","family-944","MRPS25",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005840,GO:0003735,GO:0005763,GO:0006412","ribosome,structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","GO:0005739,GO:0005840,GO:0003735,GO:0005737,GO:0005763,GO:0006412","mitochondrion,ribosome,structural constituent of ribosome,cytoplasm,mitochondrial small ribosomal subunit,translation","."]
["RPP21","ribonuclease P/MRP 21kDa subunit [Source:HGNC Symbol;Acc:21300]","ENSG00000241863","ENSP00000408610",1,"Rpr2[1]","family-945","RPP21",".",".","ncRNA","P/MRP RNA","RPP21 is a protein subunit of nuclear ribonuclease P, which processes the 5-prime leader sequence of precursor tRNAs (Jarrous et al., 2001 [PubMed 11497433]).[supplied by OMIM, Jan 2009]",".",".",".",".",".",".","GO:0004526,GO:0008033","ribonuclease P activity,tRNA processing","GO:0004526,GO:0005730,GO:0042493,GO:0008033","ribonuclease P activity,nucleolus,response to drug,tRNA processing","."]
["ZMAT2","zinc finger, matrin-type 2 [Source:HGNC Symbol;Acc:26433]","ENSG00000146007","ENSP00000473397",1,"zf-C2H2_jaz[1]","family-946","ZMAT2",".",".","snRNA","snRNA/mRNA","Snu23 yeast homolog",".",".",".",".",".",".",".",".","GO:0008270,GO:0003676,GO:0005515,GO:0003677,GO:0005634","zinc ion binding,nucleic acid binding,protein binding,DNA binding,nucleus","."]
["IFIT1","interferon-induced protein with tetratricopeptide repeats 1 [Source:HGNC Symbol;Acc:5407]","ENSG00000185745","ENSP00000360869",5,"TPR_1[1],TPR_11[2],TPR_12[1],TPR_16[1]","family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","IFIT1","IFIT1B[67,67],IFIT5[55,55],IFIT3[42,41],IFIT2[44,45]","ncRNA","viral RNA",21642987,".",".",".",".",".",".","GO:0071360,GO:0003723","cellular response to exogenous dsRNA,RNA binding","GO:0005515,GO:0009615,GO:0050688,GO:0071360,GO:0071357,GO:0003723,GO:0005737,GO:0005829,GO:0045071,GO:0019221,GO:0032091,GO:0051607,GO:0050689,GO:0045070,GO:0060337,GO:0051097,GO:0019060","protein binding,response to virus,regulation of defense response to virus,cellular response to exogenous dsRNA,cellular response to type I interferon,RNA binding,cytoplasm,cytosol,negative regulation of viral genome replication,cytokine-mediated signaling pathway,negative regulation of protein binding,defense response to virus,negative regulation of defense response to virus by host,positive regulation of viral genome replication,type I interferon signaling pathway,negative regulation of helicase activity,intracellular transport of viral protein in host cell","."]
["IFIT2","interferon-induced protein with tetratricopeptide repeats 2 [Source:HGNC Symbol;Acc:5409]","ENSG00000119922","ENSP00000360891",2,"TPR_11[1],TPR_12[1]","family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","IFIT1","IFIT1B[67,67],IFIT5[55,55],IFIT3[42,41],IFIT2[44,45]","ncRNA","putative viral RNA",22825553,".","novel",".",1,".",".","GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0005737,GO:0005829,GO:0005783,GO:0009615,GO:0043065,GO:0019221,GO:0032091,GO:0051607,GO:0008637,GO:0035457,GO:0060337","RNA binding,protein binding,cytoplasm,cytosol,endoplasmic reticulum,response to virus,positive regulation of apoptotic process,cytokine-mediated signaling pathway,negative regulation of protein binding,defense response to virus,apoptotic mitochondrial changes,cellular response to interferon-alpha,type I interferon signaling pathway","."]
["IFIT5","interferon-induced protein with tetratricopeptide repeats 5 [Source:HGNC Symbol;Acc:13328]","ENSG00000152778","ENSP00000360860",5,"TPR_1[1],TPR_19[1],TPR_11[2],TPR_12[1]","family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","IFIT1","IFIT1B[67,67],IFIT5[55,55],IFIT3[42,41],IFIT2[44,45]","tRNA","tRNA/ viral RNA",23317505,"candidate mRNA binder",".",".",1,".",".","GO:0003723,GO:0003727,GO:0000049","RNA binding,single-stranded RNA binding,tRNA binding","GO:0005515,GO:0003723,GO:0003727,GO:0000049,GO:0045177,GO:0015629,GO:0032587,GO:0045087,GO:0051607","protein binding,RNA binding,single-stranded RNA binding,tRNA binding,apical part of cell,actin cytoskeleton,ruffle membrane,innate immune response,defense response to virus","."]
["IFIT1B","interferon-induced protein with tetratricopeptide repeats 1B [Source:HGNC Symbol;Acc:23442]","ENSG00000204010","ENSP00000360874",5,"TPR_1[1],TPR_11[2],TPR_12[2]","family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","IFIT1","IFIT1B[67,67],IFIT5[55,55],IFIT3[42,41],IFIT2[44,45]","ncRNA","putative viral RNA",24371270,".",".",".",".",".",".","GO:0071360","cellular response to exogenous dsRNA","GO:0005515,GO:0009615,GO:0050688,GO:0071360,GO:0071357","protein binding,response to virus,regulation of defense response to virus,cellular response to exogenous dsRNA,cellular response to type I interferon","."]
["IFIT3","interferon-induced protein with tetratricopeptide repeats 3 [Source:HGNC Symbol;Acc:5411]","ENSG00000119917","ENSP00000360883",4,"TPR_19[1],TPR_8[1],TPR_11[1],TPR_12[1]","family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","IFIT1","IFIT1B[67,67],IFIT5[55,55],IFIT3[42,41],IFIT2[44,45]","ncRNA","putative viral RNA","by homology",".",".",".",".",".",".",".",".","GO:0005515,GO:0042802,GO:0005737,GO:0005739,GO:0005829,GO:0008285,GO:0043066,GO:0009615,GO:0019221,GO:0051607,GO:0035457,GO:0060337","protein binding,identical protein binding,cytoplasm,mitochondrion,cytosol,negative regulation of cell proliferation,negative regulation of apoptotic process,response to virus,cytokine-mediated signaling pathway,defense response to virus,cellular response to interferon-alpha,type I interferon signaling pathway","."]
["NOVA1","neuro-oncological ventral antigen 1 [Source:HGNC Symbol;Acc:7886]","ENSG00000139910","ENSP00000438875",3,"KH_1[3]","family-948","NOVA1,NOVA2","NOVA1","NOVA2[72,74]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0003729,GO:0000398,GO:0008380,GO:0006396","RNA binding,mRNA binding,mRNA splicing, via spliceosome,RNA splicing,RNA processing","GO:0003723,GO:0003729,GO:0000398,GO:0005634,GO:0008380,GO:0006396,GO:0007626,GO:0007268","RNA binding,mRNA binding,mRNA splicing, via spliceosome,nucleus,RNA splicing,RNA processing,locomotory behavior,synaptic transmission","."]
["NOVA2","neuro-oncological ventral antigen 2 [Source:HGNC Symbol;Acc:7887]","ENSG00000104967","ENSP00000263257",3,"KH_1[3]","family-948","NOVA1,NOVA2","NOVA1","NOVA2[72,74]","mRNA","mRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005634","RNA binding,nucleus","."]
["SNRPD3","small nuclear ribonucleoprotein D3 polypeptide 18kDa [Source:HGNC Symbol;Acc:11160]","ENSG00000100028","ENSP00000215829",1,"LSM[1]","family-949","SNRPD3",".",".","snRNA","snRNA","established RBP ","RNAbinding",".",".",1,".",1,"GO:0071208,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0016070,GO:0008380,GO:0000398,GO:0031124,GO:0000387,GO:0034660,GO:0008334,GO:0030529","histone pre-mRNA DCP binding,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,histone mRNA metabolic process,ribonucleoprotein complex","GO:0005515,GO:0019899,GO:0071208,GO:0005829,GO:0005654,GO:0005681,GO:0030532,GO:0005689,GO:0071013,GO:0005683,GO:0006366,GO:0010467,GO:0016070,GO:0008380,GO:0000398,GO:0031124,GO:0000387,GO:0034660,GO:0006369,GO:0008334,GO:0030529,GO:0019013,GO:0005737,GO:0005634","protein binding,enzyme binding,histone pre-mRNA DCP binding,cytosol,nucleoplasm,spliceosomal complex,small nuclear ribonucleoprotein complex,U12-type spliceosomal complex,catalytic step 2 spliceosome,U7 snRNP,transcription from RNA polymerase II promoter,gene expression,RNA metabolic process,RNA splicing,mRNA splicing, via spliceosome,mRNA 3'-end processing,spliceosomal snRNP assembly,ncRNA metabolic process,termination of RNA polymerase II transcription,histone mRNA metabolic process,ribonucleoprotein complex,viral nucleocapsid,cytoplasm,nucleus","."]
["YARS2","tyrosyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:24249]","ENSG00000139131","ENSP00000320658",1,"tRNA-synt_1b[1]","family-95","YARS2",".",".","tRNA","tRNA","established RBP ","RNAbinding",".",".",1,1,".","GO:0004812,GO:0004831,GO:0006418,GO:0006437,GO:0000049,GO:0006412,GO:0043039,GO:0070184","aminoacyl-tRNA ligase activity,tyrosine-tRNA ligase activity,tRNA aminoacylation for protein translation,tyrosyl-tRNA aminoacylation,tRNA binding,translation,tRNA aminoacylation,mitochondrial tyrosyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004831,GO:0005737,GO:0006418,GO:0006437,GO:0042803,GO:0000049,GO:0072545,GO:0005739,GO:0005759,GO:0006412,GO:0010467,GO:0043039,GO:0070184","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,tyrosine-tRNA ligase activity,cytoplasm,tRNA aminoacylation for protein translation,tyrosyl-tRNA aminoacylation,protein homodimerization activity,tRNA binding,tyrosine binding,mitochondrion,mitochondrial matrix,translation,gene expression,tRNA aminoacylation,mitochondrial tyrosyl-tRNA aminoacylation"," MYOPATHY, LACTIC ACIDOSIS, AND SIDEROBLASTIC ANEMIA 2; MLASA2"]
["PTCD1","pentatricopeptide repeat domain 1 [Source:HGNC Symbol;Acc:22198] [Type: protein coding Ensembl/Havana merge]","ENSG00000106246","ENSP00000292478",2,"PPR_2[2]","family-950","PTCD1",".",".","tRNA","putative tRNA",21857155,"candidate mRNA binder","novel",1,1,1,".","GO:0000049,GO:0042780","tRNA binding,tRNA 3'-end processing","GO:0000049,GO:0005739,GO:0005759,GO:0042780","tRNA binding,mitochondrion,mitochondrial matrix,tRNA 3'-end processing","."]
["TSR1","TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25542]","ENSG00000167721","ENSP00000301364",2,"DUF663[1],AARP2CN[1]","family-951","TSR1",".",".","rRNA","rRNA",20805244,".","novel",".",1,".",".","GO:0042254,GO:0042255","ribosome biogenesis,ribosome assembly","GO:0005634,GO:0042254,GO:0005730,GO:0042255","nucleus,ribosome biogenesis,nucleolus,ribosome assembly","."]
["MRPS6","mitochondrial ribosomal protein S6 [Source:HGNC Symbol;Acc:14051]","ENSG00000243927","ENSP00000382250",1,"Ribosomal_S6[1]","family-952","MRPS6",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0019843,GO:0005840,GO:0015935,GO:0006412","structural constituent of ribosome,rRNA binding,ribosome,small ribosomal subunit,translation","GO:0003735,GO:0019843,GO:0005739,GO:0005840,GO:0015935,GO:0006412","structural constituent of ribosome,rRNA binding,mitochondrion,ribosome,small ribosomal subunit,translation","."]
["TAF9","TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa [Source:HGNC Symbol;Acc:11542]","ENSG00000085231","ENSP00000370193",1,"TFIID-31kDa[1]","family-953","TAF9,TAF9B","TAF9","TAF9B[77,81]","snoRNA","snoRNA",17636026,".",".",".",".",".",".","GO:0070761","pre-snoRNP complex","GO:0003677,GO:0046982,GO:0005634,GO:0045944,GO:0006352,GO:0005515,GO:0002039,GO:0003713,GO:0033613,GO:0044212,GO:0004402,GO:0070742,GO:0005654,GO:0030914,GO:0071339,GO:0005669,GO:0033276,GO:0070761,GO:0000125,GO:0043066,GO:0006366,GO:0006974,GO:0016032,GO:0010467,GO:0006367,GO:0030307,GO:0006368,GO:0070555,GO:0050821,GO:0032435,GO:0043966,GO:1902166,GO:0060760,GO:0005524,GO:0004017,GO:0015030","DNA binding,protein heterodimerization activity,nucleus,positive regulation of transcription from RNA polymerase II promoter,DNA-dependent transcription, initiation,protein binding,p53 binding,transcription coactivator activity,activating transcription factor binding,transcription regulatory region DNA binding,histone acetyltransferase activity,C2H2 zinc finger domain binding,nucleoplasm,STAGA complex,MLL1 complex,transcription factor TFIID complex,transcription factor TFTC complex,pre-snoRNP complex,PCAF complex,negative regulation of apoptotic process,transcription from RNA polymerase II promoter,cellular response to DNA damage stimulus,viral process,gene expression,transcription initiation from RNA polymerase II promoter,positive regulation of cell growth,transcription elongation from RNA polymerase II promoter,response to interleukin-1,protein stabilization,negative regulation of proteasomal ubiquitin-dependent protein catabolic process,histone H3 acetylation,negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator,positive regulation of response to cytokine stimulus,ATP binding,adenylate kinase activity,Cajal body","."]
["RPL11","ribosomal protein L11 [Source:HGNC Symbol;Acc:10301]","ENSG00000142676","ENSP00000398888",2,"Ribosomal_L5[1],Ribosomal_L5_C[1]","family-954","RPL11",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0019843,GO:0022625,GO:0016070,GO:0016071,GO:0006364,GO:0042273,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,rRNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,rRNA processing,ribosomal large subunit biogenesis,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005515,GO:0019843,GO:0005829,GO:0005730,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0006364,GO:0034504,GO:0044267,GO:0006605,GO:0006614,GO:0042273,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,ribosome,translation,RNA binding,protein binding,rRNA binding,cytosol,nucleolus,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,rRNA processing,protein localization to nucleus,cellular protein metabolic process,protein targeting,SRP-dependent cotranslational protein targeting to membrane,ribosomal large subunit biogenesis,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription"," DIAMOND-BLACKFAN ANEMIA 7; DBA7"]
["DDX23","DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Source:HGNC Symbol;Acc:17347]","ENSG00000174243","ENSP00000310723",2,"Helicase_C[1],DEAD[1]","family-955","DDX23,DDX59","DDX23","DDX59[22,29]","snRNA","snRNA","9539711, The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]","helicase",".",".",1,".",".","GO:0004004,GO:0071013,GO:0005682,GO:0008380,GO:0000398,GO:0000375,GO:0000354","ATP-dependent RNA helicase activity,catalytic step 2 spliceosome,U5 snRNP,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,cis assembly of pre-catalytic spliceosome","GO:0005634,GO:0005886,GO:0005739,GO:0004386,GO:0005524,GO:0003676,GO:0008026,GO:0005515,GO:0004004,GO:0005654,GO:0071013,GO:0005682,GO:0010467,GO:0008380,GO:0000398,GO:0000375,GO:0000354","nucleus,plasma membrane,mitochondrion,helicase activity,ATP binding,nucleic acid binding,ATP-dependent helicase activity,protein binding,ATP-dependent RNA helicase activity,nucleoplasm,catalytic step 2 spliceosome,U5 snRNP,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions,cis assembly of pre-catalytic spliceosome","."]
["DDX59","DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Source:HGNC Symbol;Acc:25360]","ENSG00000118197","ENSP00000356317",3,"zf-HIT[1],Helicase_C[1],DEAD[1]","family-955","DDX23,DDX59","DDX23","DDX59[22,29]","mRNA","mRNA","PRP28 yeast homolog",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0005524,GO:0003676,GO:0008026,GO:0004386,GO:0003723,GO:0046872,GO:0005622","ATP binding,nucleic acid binding,ATP-dependent helicase activity,helicase activity,RNA binding,metal ion binding,intracellular","."]
["CCNT2","cyclin T2 [Source:HGNC Symbol;Acc:1600","ENSG00000082258","ENSP00000264157",1,"Cyclin_N[1]","family-956","CCNC,CCNT1,CCNT2,CCNK,CCNL1,CCNL2,FAM58A","CCNC","CCNT1[20,8],CCNT2[20,8],CCNK[27,13],CCNL1[28,15],CCNL2[28,15],FAM58A[17,20]","ncRNA","7SK","The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]",".",".",".",".",".",".",".",".","GO:0019901,GO:0006355,GO:0000079,GO:0005634,GO:0005654,GO:0006351,GO:0045944,GO:0006366,GO:0051301,GO:0016032,GO:0010467,GO:0007049,GO:0006367,GO:0007179,GO:0006368,GO:0019048","protein kinase binding,regulation of transcription, DNA-dependent,regulation of cyclin-dependent protein serine/threonine kinase activity,nucleus,nucleoplasm,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,cell division,viral process,gene expression,cell cycle,transcription initiation from RNA polymerase II promoter,transforming growth factor beta receptor signaling pathway,transcription elongation from RNA polymerase II promoter,modulation by virus of host morphology or physiology","."]
["CCNT1","cyclin T1 [Source:HGNC Symbol;Acc:1599]","ENSG00000129315","ENSP00000261900",1,"Cyclin_N[1]","family-956","CCNC,CCNT1,CCNT2,CCNK,CCNL1,CCNL2,FAM58A","CCNC","CCNT1[20,8],CCNT2[20,8],CCNK[27,13],CCNL1[28,15],CCNL2[28,15],FAM58A[17,20]","ncRNA","7SK","This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]",".",".",".",".",".",".","GO:0017069","snRNA binding","GO:0019901,GO:0006355,GO:0000079,GO:0005515,GO:0003677,GO:0003682,GO:0044212,GO:0017069,GO:0005634,GO:0005654,GO:0008024,GO:0006351,GO:0045944,GO:0006366,GO:0051301,GO:0016032,GO:0010467,GO:0007049,GO:0006468,GO:0006367,GO:0007179,GO:0006368,GO:0019048,GO:0050434","protein kinase binding,regulation of transcription, DNA-dependent,regulation of cyclin-dependent protein serine/threonine kinase activity,protein binding,DNA binding,chromatin binding,transcription regulatory region DNA binding,snRNA binding,nucleus,nucleoplasm,positive transcription elongation factor complex b,transcription, DNA-templated,positive regulation of transcription from RNA polymerase II promoter,transcription from RNA polymerase II promoter,cell division,viral process,gene expression,cell cycle,protein phosphorylation,transcription initiation from RNA polymerase II promoter,transforming growth factor beta receptor signaling pathway,transcription elongation from RNA polymerase II promoter,modulation by virus of host morphology or physiology,positive regulation of viral transcription","."]
["RPL8","ribosomal protein L8 [Source:HGNC Symbol;Acc:10368]","ENSG00000161016","ENSP00000435313",2,"Ribosomal_L2_C[1],Ribosomal_L2[1]","family-957","RPL8",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0019843,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,rRNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0019843,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,rRNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["SARNP","SAP domain containing ribonucleoprotein [Source:HGNC Symbol;Acc:24432]","ENSG00000205323","ENSP00000337632",1,"SAP[1]","family-958","SARNP",".",".","mRNA","mRNA",20844015,"RNAbinding","RNAbinding",1,1,1,".","GO:0003723,GO:0006417,GO:0006406","RNA binding,regulation of translation,mRNA export from nucleus","GO:0005634,GO:0043231,GO:0003676,GO:0003723,GO:0003677,GO:0016607,GO:0000346,GO:0006351,GO:0006355,GO:0006417,GO:0006406","nucleus,intracellular membrane-bounded organelle,nucleic acid binding,RNA binding,DNA binding,nuclear speck,transcription export complex,transcription, DNA-templated,regulation of transcription, DNA-dependent,regulation of translation,mRNA export from nucleus","."]
["IMP3","IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast) [Source:HGNC Symbol;Acc:14497]","ENSG00000177971","ENSP00000326981",2,"Ribosomal_S4[1],S4[1]","family-959","IMP3",".",".","snoRNA","snoRNA","This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]","ribosomal","RNAbinding",1,1,1,".","GO:0003723,GO:0019843,GO:0030529,GO:0006364","RNA binding,rRNA binding,ribonucleoprotein complex,rRNA processing","GO:0003723,GO:0005515,GO:0019843,GO:0005634,GO:0005622,GO:0005730,GO:0030529,GO:0006364","RNA binding,protein binding,rRNA binding,nucleus,intracellular,nucleolus,ribonucleoprotein complex,rRNA processing","."]
["SRRM4","serine/arginine repetitive matrix 4 [Source:HGNC Symbol;Acc:29389]","ENSG00000139767","ENSP00000267260",1,"SRRM_C[1]","family-96","SRRM4",".",".","mRNA","mRNA","SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]",".",".",".",".",".",".","GO:0003729,GO:0006397,GO:0043484,GO:0000381,GO:0008380","mRNA binding,mRNA processing,regulation of RNA splicing,regulation of alternative mRNA splicing, via spliceosome,RNA splicing","GO:0003729,GO:0005634,GO:0006397,GO:0043484,GO:0030154,GO:0000381,GO:0007399,GO:0008380,GO:0007605","mRNA binding,nucleus,mRNA processing,regulation of RNA splicing,cell differentiation,regulation of alternative mRNA splicing, via spliceosome,nervous system development,RNA splicing,sensory perception of sound","."]
["CNP","2',3'-cyclic nucleotide 3' phosphodiesterase [Source:HGNC Symbol;Acc:2158]","ENSG00000173786","ENSP00000377470",2,"CNPase[1],AAA_33[1]","family-960","CNP",".",".","mRNA","putative mRNA",19021295,".",".",".",".",".",".","GO:0003723,GO:0004113","RNA binding,2',3'-cyclic-nucleotide 3'-phosphodiesterase activity","GO:0003723,GO:0005524,GO:0003824,GO:0016301,GO:0004113,GO:0030551,GO:0005886,GO:0005737,GO:0016020,GO:0048471,GO:0005615,GO:0005874,GO:0005741,GO:0005743,GO:0042470,GO:0035748,GO:0031143,GO:0005902,GO:0035749,GO:0007409,GO:0007568,GO:0032496,GO:0009636,GO:0007268,GO:0000226,GO:0008344,GO:0009214,GO:0030900,GO:0046902,GO:0042995","RNA binding,ATP binding,catalytic activity,kinase activity,2',3'-cyclic-nucleotide 3'-phosphodiesterase activity,cyclic nucleotide binding,plasma membrane,cytoplasm,membrane,perinuclear region of cytoplasm,extracellular space,microtubule,mitochondrial outer membrane,mitochondrial inner membrane,melanosome,myelin sheath abaxonal region,pseudopodium,microvillus,myelin sheath adaxonal region,axonogenesis,aging,response to lipopolysaccharide,response to toxic substance,synaptic transmission,microtubule cytoskeleton organization,adult locomotory behavior,cyclic nucleotide catabolic process,forebrain development,regulation of mitochondrial membrane permeability,cell projection","."]
["LIN28A","lin-28 homolog A (C. elegans) [Source:HGNC Symbol;Acc:15986]","ENSG00000131914","ENSP00000254231",2,"zf-CCHC[1],CSD[1]","family-961","LIN28A,LIN28B","LIN28A","LIN28B[63,53]","mRNA","mRNA/miRNA/snoRNA","established RBP ",".",".",".",".",1,1,"GO:0003723,GO:0003729,GO:0031369,GO:0035198,GO:0000932,GO:0010494,GO:0045727,GO:0031054,GO:0060964,GO:0010587,GO:0031123,GO:0010586","RNA binding,mRNA binding,translation initiation factor binding,miRNA binding,cytoplasmic mRNA processing body,cytoplasmic stress granule,positive regulation of translation,pre-miRNA processing,regulation of gene silencing by miRNA,miRNA catabolic process,RNA 3'-end processing,miRNA metabolic process","GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0003677,GO:0003729,GO:0031369,GO:0035198,GO:0005634,GO:0005737,GO:0000932,GO:0005730,GO:0010494,GO:0045666,GO:0006355,GO:0019827,GO:0007281,GO:0045727,GO:0031054,GO:0045686,GO:0060964,GO:0010587,GO:0031123,GO:0048863,GO:0010586","RNA binding,protein binding,zinc ion binding,nucleic acid binding,DNA binding,mRNA binding,translation initiation factor binding,miRNA binding,nucleus,cytoplasm,cytoplasmic mRNA processing body,nucleolus,cytoplasmic stress granule,positive regulation of neuron differentiation,regulation of transcription, DNA-dependent,stem cell maintenance,germ cell development,positive regulation of translation,pre-miRNA processing,negative regulation of glial cell differentiation,regulation of gene silencing by miRNA,miRNA catabolic process,RNA 3'-end processing,stem cell differentiation,miRNA metabolic process","."]
["LIN28B","lin-28 homolog B (C. elegans) [Source:HGNC Symbol;Acc:32207]","ENSG00000187772","ENSP00000344401",2,"zf-CCHC[1],CSD[1]","family-961","LIN28A,LIN28B","LIN28A","LIN28B[63,53]","mRNA","mRNA/miRNA/snoRNA","established RBP ","RNAbinding",".",".",1,1,1,"GO:0003723,GO:0031054,GO:0010587,GO:0031123","RNA binding,pre-miRNA processing,miRNA catabolic process,RNA 3'-end processing","GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0003677,GO:0005634,GO:0005737,GO:0005739,GO:0006355,GO:0031054,GO:0010587,GO:0031123","RNA binding,protein binding,zinc ion binding,nucleic acid binding,DNA binding,nucleus,cytoplasm,mitochondrion,regulation of transcription, DNA-dependent,pre-miRNA processing,miRNA catabolic process,RNA 3'-end processing","."]
["EIF3K","eukaryotic translation initiation factor 3, subunit K [Source:HGNC Symbol;Acc:24656]","ENSG00000178982","ENSP00000248342",1,"PCI_Csn8[1]","family-962","EIF3K",".",".","mRNA","putative mRNA",15180986,".",".",".",".",".",".","GO:0003743,GO:0043022,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413,GO:0006412","translation initiation factor activity,ribosome binding,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation,translation","GO:0005488,GO:0003743,GO:0043022,GO:0005634,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0005515,GO:0005829,GO:0006413,GO:0006412,GO:0010467,GO:0044267","binding,translation initiation factor activity,ribosome binding,nucleus,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,protein binding,cytosol,translational initiation,translation,gene expression,cellular protein metabolic process","."]
["SF3B14","Pre-mRNA branch site protein p14  [Source:UniProtKB/Swiss-Prot;Acc:Q9Y3B4]","ENSG00000115128","ENSP00000233468",1,"RRM_1[1]","family-963","SF3B14",".",".","mRNA","putative mRNA","established RBP ","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0005689,GO:0008380,GO:0000398","RNA binding,U12-type spliceosomal complex,RNA splicing,mRNA splicing, via spliceosome","GO:0000166,GO:0003723,GO:0003676,GO:0005654,GO:0005689,GO:0010467,GO:0008380,GO:0000398","nucleotide binding,RNA binding,nucleic acid binding,nucleoplasm,U12-type spliceosomal complex,gene expression,RNA splicing,mRNA splicing, via spliceosome","."]
["EIF2S2","eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa [Source:HGNC Symbol;Acc:3266]","ENSG00000125977","ENSP00000364119",1,"eIF-5_eIF-2B[1]","family-964","EIF2S2",".",".","tRNA","tRNA","The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]","translationfactor","RNAbinding",1,1,".",".","GO:0003723,GO:0003743,GO:0008135,GO:0005850,GO:0006412,GO:0006413","RNA binding,translation initiation factor activity,translation factor activity, nucleic acid binding,eukaryotic translation initiation factor 2 complex,translation,translational initiation","GO:0003723,GO:0005515,GO:0046872,GO:0003743,GO:0008135,GO:0005829,GO:0005850,GO:0006412,GO:0010467,GO:0008584,GO:0001701,GO:0044267,GO:0002176,GO:0006413","RNA binding,protein binding,metal ion binding,translation initiation factor activity,translation factor activity, nucleic acid binding,cytosol,eukaryotic translation initiation factor 2 complex,translation,gene expression,male gonad development,in utero embryonic development,cellular protein metabolic process,male germ cell proliferation,translational initiation","."]
["RNMT","RNA (guanine-7-) methyltransferase [Source:HGNC Symbol;Acc:10075]","ENSG00000101654","ENSP00000372804",1,"Pox_MCEL[1]","family-965","RNMT",".",".","mRNA","mRNA",7275966,".",".",".",".",".",".","GO:0003723,GO:0004482,GO:0005845,GO:0006370,GO:0036265","RNA binding,mRNA (guanine-N7-)-methyltransferase activity,mRNA cap binding complex,7-methylguanosine mRNA capping,RNA (guanine-N7)-methylation","GO:0003723,GO:0005515,GO:0008168,GO:0004482,GO:0005634,GO:0005730,GO:0005654,GO:0005845,GO:0006366,GO:0016032,GO:0010467,GO:0008152,GO:0006370,GO:0036265","RNA binding,protein binding,methyltransferase activity,mRNA (guanine-N7-)-methyltransferase activity,nucleus,nucleolus,nucleoplasm,mRNA cap binding complex,transcription from RNA polymerase II promoter,viral process,gene expression,metabolic process,7-methylguanosine mRNA capping,RNA (guanine-N7)-methylation","."]
["MRPL42","mitochondrial ribosomal protein L42 [Source:HGNC Symbol;Acc:14493]","ENSG00000198015","ENSP00000449884",1,"MRP-S32[1]","family-966","MRPL42",".",".","ribosome","mitochondrial ribosome","established RBP ",".","RNArelated",".",1,".",".","GO:0005840,GO:0003735,GO:0005763,GO:0006412","ribosome,structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","GO:0005886,GO:0005739,GO:0005840,GO:0003735,GO:0005763,GO:0006412","plasma membrane,mitochondrion,ribosome,structural constituent of ribosome,mitochondrial small ribosomal subunit,translation","."]
["THRAP3","thyroid hormone receptor associated protein 3 [Source:HGNC Symbol;Acc:22964]","ENSG00000054118","ENSP00000433825",1,"THRAP3_BCLAF1[1]","family-967","BCLAF1,THRAP3,CXorf23","BCLAF1","THRAP3[39,38],CXorf23[14,20]","mRNA","mRNA",22424773,"RNAbinding","RNArelated",1,1,1,".","GO:0006397,GO:0008380,GO:0000381,GO:0048026,GO:0048255,GO:0000956","mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,positive regulation of mRNA splicing, via spliceosome,mRNA stabilization,nuclear-transcribed mRNA catabolic process","GO:0016592,GO:0005515,GO:0005524,GO:0001104,GO:0004872,GO:0042809,GO:0003713,GO:0046966,GO:0003712,GO:0030374,GO:0051219,GO:0005634,GO:0043231,GO:0035145,GO:0045944,GO:0045893,GO:0006397,GO:0008380,GO:0000381,GO:0006367,GO:0030521,GO:0048026,GO:0030518,GO:0048255,GO:0000956","mediator complex,protein binding,ATP binding,RNA polymerase II transcription cofactor activity,receptor activity,vitamin D receptor binding,transcription coactivator activity,thyroid hormone receptor binding,transcription cofactor activity,ligand-dependent nuclear receptor transcription coactivator activity,phosphoprotein binding,nucleus,intracellular membrane-bounded organelle,exon-exon junction complex,positive regulation of transcription from RNA polymerase II promoter,positive regulation of transcription, DNA-dependent,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,transcription initiation from RNA polymerase II promoter,androgen receptor signaling pathway,positive regulation of mRNA splicing, via spliceosome,intracellular steroid hormone receptor signaling pathway,mRNA stabilization,nuclear-transcribed mRNA catabolic process","."]
["BCLAF1","BCL2-associated transcription factor 1 [Source:HGNC Symbol;Acc:16863]","ENSG00000029363","ENSP00000376159",1,"THRAP3_BCLAF1[1]","family-967","BCLAF1,THRAP3,CXorf23","BCLAF1","THRAP3[39,38],CXorf23[14,20]","mRNA","mRNA",23778535,"candidate mRNA binder","novel",1,1,1,".",".",".","GO:0005634,GO:0006915,GO:0045892,GO:2001022,GO:0005515,GO:0003677,GO:0005737,GO:0005730,GO:0006351,GO:0043065,GO:2001244,GO:0043620,GO:2000144","nucleus,apoptotic process,negative regulation of transcription, DNA-dependent,positive regulation of response to DNA damage stimulus,protein binding,DNA binding,cytoplasm,nucleolus,transcription, DNA-templated,positive regulation of apoptotic process,positive regulation of intrinsic apoptotic signaling pathway,regulation of DNA-dependent transcription in response to stress,positive regulation of DNA-dependent transcription, initiation","."]
["CXorf23","chromosome X open reading frame 23 [Source:HGNC Symbol;Acc:27413]","ENSG00000173681","ENSP00000349470",1,"THRAP3_BCLAF1[1]","family-967","BCLAF1,THRAP3,CXorf23","BCLAF1","THRAP3[39,38],CXorf23[14,20]","mRNA","putative mRNA","by domain",".",".",".",".",".",".",".",".","GO:0005739","mitochondrion","."]
["PNO1","partner of NOB1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:32790]","ENSG00000115946","ENSP00000263657",1,"KH_1[1]","family-968","PNO1",".",".","rRNA","rRNA","21075849, 12736301","RNAbinding",".",".",1,".",1,"GO:0003723","RNA binding","GO:0003723,GO:0005730","RNA binding,nucleolus","."]
["RBM4","RNA binding motif protein 4 [Source:HGNC Symbol;Acc:9901]","ENSG00000173933","ENSP00000309166",3,"RRM_1[2],zf-CCHC[1]","family-969","RBM14,RBM14-RBM4,RBM4,RBM4B","RBM14","RBM14-RBM4[27,53],RBM4[19,35],RBM4B[19,36]","mRNA","mRNA",18723113,"RNAbinding","experimentally validated",1,1,".",1,"GO:0003723,GO:0003729,GO:0003730,GO:0097157,GO:0035198,GO:0097158,GO:0010494,GO:0006397,GO:0008380,GO:0000381,GO:0006396","RNA binding,mRNA binding,mRNA 3'-UTR binding,pre-mRNA intronic binding,miRNA binding,pre-mRNA intronic pyrimidine-rich binding,cytoplasmic stress granule,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,RNA processing","GO:0000166,GO:0003723,GO:0005515,GO:0008270,GO:0003676,GO:0003729,GO:0003730,GO:0097157,GO:0035198,GO:0097158,GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0010494,GO:0016607,GO:0030154,GO:0046685,GO:0006397,GO:0008380,GO:0000381,GO:0006396,GO:0017148,GO:0046822,GO:0032055,GO:0051403,GO:0043153,GO:0045947,GO:0035278,GO:0051149,GO:0002190,GO:0002192,GO:0097167","nucleotide binding,RNA binding,protein binding,zinc ion binding,nucleic acid binding,mRNA binding,mRNA 3'-UTR binding,pre-mRNA intronic binding,miRNA binding,pre-mRNA intronic pyrimidine-rich binding,nucleus,cytoplasm,nucleolus,nucleoplasm,cytoplasmic stress granule,nuclear speck,cell differentiation,response to arsenic-containing substance,mRNA processing,RNA splicing,regulation of alternative mRNA splicing, via spliceosome,RNA processing,negative regulation of translation,regulation of nucleocytoplasmic transport,negative regulation of translation in response to stress,stress-activated MAPK cascade,entrainment of circadian clock by photoperiod,negative regulation of translational initiation,negative regulation of translation involved in gene silencing by miRNA,positive regulation of muscle cell differentiation,cap-independent translational initiation,IRES-dependent translational initiation,circadian regulation of translation","."]
["RBM4B","RNA binding motif protein 4B [Source:HGNC Symbol;Acc:28842]","ENSG00000173914","ENSP00000310471",3,"RRM_1[2],zf-CCHC[1]","family-969","RBM14,RBM14-RBM4,RBM4,RBM4B","RBM14","RBM14-RBM4[27,53],RBM4[19,35],RBM4B[19,36]","mRNA","putative mRNA","by homology","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006417,GO:0006397,GO:0008380","RNA binding,regulation of translation,mRNA processing,RNA splicing","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0008270,GO:0005730,GO:0006417,GO:0006397,GO:0008380,GO:0010628,GO:0032922,GO:0007623,GO:0043153","nucleotide binding,nucleic acid binding,RNA binding,protein binding,zinc ion binding,nucleolus,regulation of translation,mRNA processing,RNA splicing,positive regulation of gene expression,circadian regulation of gene expression,circadian rhythm,entrainment of circadian clock by photoperiod","."]
["RBM14","RNA binding motif protein 14 [Source:HGNC Symbol;Acc:14219]","ENSG00000239306","ENSP00000311747",2,"RRM_1[2]","family-969","RBM14,RBM14-RBM4,RBM4,RBM4B","RBM14","RBM14-RBM4[27,53],RBM4[19,35],RBM4B[19,36]","mRNA","mRNA","This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0000166,GO:0003723,GO:0005515,GO:0001104,GO:0003676,GO:0030674,GO:0030374,GO:0005634,GO:0005667,GO:0016592,GO:0030529,GO:0045944,GO:0006281,GO:0006310,GO:0006260,GO:0009725,GO:0016575,GO:0030520,GO:0042921","nucleotide binding,RNA binding,protein binding,RNA polymerase II transcription cofactor activity,nucleic acid binding,protein binding, bridging,ligand-dependent nuclear receptor transcription coactivator activity,nucleus,transcription factor complex,mediator complex,ribonucleoprotein complex,positive regulation of transcription from RNA polymerase II promoter,DNA repair,DNA recombination,DNA replication,response to hormone,histone deacetylation,intracellular estrogen receptor signaling pathway,glucocorticoid receptor signaling pathway","."]
["R3HCC1","R3H domain and coiled-coil containing 1 [Source:HGNC Symbol;Acc:27329]","ENSG00000104679","ENSP00000397555",2,"R3H[1],DUF2414[1]","family-97","R3HCC1,R3HCC1L","R3HCC1","R3HCC1L[34,11]","unknown","unknown","by domain",".",".",".",".",".",".",".",".","GO:0000166,GO:0003676","nucleotide binding,nucleic acid binding","."]
["R3HCC1L","R3H domain and coiled-coil containing 1-like [Source:HGNC Symbol;Acc:23512]","ENSG00000166024","ENSP00000314018",1,"DUF2414[1]","family-97","R3HCC1,R3HCC1L","R3HCC1","R3HCC1L[34,11]","unknown","unknown","by domain",".",".",".",".",".",".",".",".","GO:0000166,GO:0035145","nucleotide binding,exon-exon junction complex","."]
["KIAA0430","KIAA0430 [Source:HGNC Symbol;Acc:29562]","ENSG00000166783","ENSP00000379654",8,"RRM_5[1],Limkain-b1[1],NYN[1],OST-HTH[5]","family-970","KIAA0430",".",".","ncRNA","putative ncRNA / transposon",22442484,".",".",".",".",".",1,"GO:0003723","RNA binding","GO:0000166,GO:0003676,GO:0005777,GO:0048477,GO:0010468,GO:0007143,GO:0003723,GO:0030154,GO:0010923,GO:0006302","nucleotide binding,nucleic acid binding,peroxisome,oogenesis,regulation of gene expression,female meiosis,RNA binding,cell differentiation,negative regulation of phosphatase activity,double-strand break repair","."]
["POP5","processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) [Source:HGNC Symbol;Acc:17689]","ENSG00000167272","ENSP00000341791",1,"RNase_P_Rpp14[1]","family-971","POP5",".",".","ncRNA","MRP RNA","established RBP ",".",".",".",".",".",".","GO:0004540,GO:0004526,GO:0005655,GO:0016070,GO:0008033","ribonuclease activity,ribonuclease P activity,nucleolar ribonuclease P complex,RNA metabolic process,tRNA processing","GO:0005515,GO:0004540,GO:0004526,GO:0005634,GO:0005655,GO:0016070,GO:0008033","protein binding,ribonuclease activity,ribonuclease P activity,nucleus,nucleolar ribonuclease P complex,RNA metabolic process,tRNA processing","."]
["MRPL51","mitochondrial ribosomal protein L51 [Source:HGNC Symbol;Acc:14044]","ENSG00000111639","ENSP00000229238",1,"MRP-L51[1]","family-972","MRPL51",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0005761,GO:0003735,GO:0005762,GO:0006412","mitochondrial ribosome,structural constituent of ribosome,mitochondrial large ribosomal subunit,translation","GO:0005761,GO:0005515,GO:0003735,GO:0005739,GO:0005762,GO:0006412","mitochondrial ribosome,protein binding,structural constituent of ribosome,mitochondrion,mitochondrial large ribosomal subunit,translation","."]
["MARS","methionyl-tRNA synthetase [Source:HGNC Symbol;Acc:6898]","ENSG00000166986","ENSP00000262027",3,"tRNA-synt_1g[1],GST_C_3[1],WHEP-TRS[1]","family-973","MARS",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004825,GO:0004812,GO:0006431,GO:0006418,GO:0000049","methionine-tRNA ligase activity,aminoacyl-tRNA ligase activity,methionyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA binding","GO:0000166,GO:0005524,GO:0004825,GO:0004812,GO:0005737,GO:0006431,GO:0006418,GO:0000049,GO:0005739,GO:0005829,GO:0010467","nucleotide binding,ATP binding,methionine-tRNA ligase activity,aminoacyl-tRNA ligase activity,cytoplasm,methionyl-tRNA aminoacylation,tRNA aminoacylation for protein translation,tRNA binding,mitochondrion,cytosol,gene expression","."]
["TYW1","tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:25598]","ENSG00000198874","ENSP00000352645",3,"Wyosine_form[1],Flavodoxin_1[1],Radical_SAM[1]","family-974","TYW1,TYW1B","TYW1","TYW1B[44,94]","tRNA","putative tRNA","Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. [provided by RefSeq, Dec 2012]  17150819",".",".",".",".",".",".","GO:0008033","tRNA processing","GO:0016491,GO:0051539,GO:0005506,GO:0010181,GO:0008033,GO:0003824,GO:0051536","oxidoreductase activity,4 iron, 4 sulfur cluster binding,iron ion binding,FMN binding,tRNA processing,catalytic activity,iron-sulfur cluster binding","."]
["MRPL16","mitochondrial ribosomal protein L16 [Source:HGNC Symbol;Acc:14476]","ENSG00000166902","ENSP00000436592",1,"Ribosomal_L16[1]","family-975","MRPL16",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0019843,GO:0005840,GO:0006412","structural constituent of ribosome,rRNA binding,ribosome,translation","GO:0003735,GO:0019843,GO:0005739,GO:0005840,GO:0006412","structural constituent of ribosome,rRNA binding,mitochondrion,ribosome,translation","."]
["DUS1L","dihydrouridine synthase 1-like (S. cerevisiae) [Source:HGNC Symbol;Acc:30086]","ENSG00000169718","ENSP00000445110",1,"Dus[1]","family-976","DUS1L",".",".","tRNA","putative tRNA","by homology",".",".",".",".",".",".","GO:0017150,GO:0008033","tRNA dihydrouridine synthase activity,tRNA processing","GO:0050660,GO:0017150,GO:0055114,GO:0008033","flavin adenine dinucleotide binding,tRNA dihydrouridine synthase activity,oxidation-reduction process,tRNA processing","."]
["QRSL1","glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 [Source:HGNC Symbol;Acc:21020]","ENSG00000130348","ENSP00000358042",1,"Amidase[1]","family-977","QRSL1",".",".","tRNA","tRNA",19805282,".",".",".",".",".",".","GO:0050567,GO:0030956,GO:0006412,GO:0032543","glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,glutamyl-tRNA(Gln) amidotransferase complex,translation,mitochondrial translation","GO:0016884,GO:0005524,GO:0050567,GO:0005739,GO:0030956,GO:0006412,GO:0032543,GO:0070681","carbon-nitrogen ligase activity, with glutamine as amido-N-donor,ATP binding,glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity,mitochondrion,glutamyl-tRNA(Gln) amidotransferase complex,translation,mitochondrial translation,glutaminyl-tRNAGln biosynthesis via transamidation","."]
["WARS2","tryptophanyl tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:12730]","ENSG00000116874","ENSP00000235521",1,"tRNA-synt_1b[1]","family-978","WARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004812,GO:0004830,GO:0006418,GO:0006436","aminoacyl-tRNA ligase activity,tryptophan-tRNA ligase activity,tRNA aminoacylation for protein translation,tryptophanyl-tRNA aminoacylation","GO:0000166,GO:0005524,GO:0004812,GO:0004830,GO:0005737,GO:0005739,GO:0006418,GO:0001570,GO:0006436,GO:0005759,GO:0010467","nucleotide binding,ATP binding,aminoacyl-tRNA ligase activity,tryptophan-tRNA ligase activity,cytoplasm,mitochondrion,tRNA aminoacylation for protein translation,vasculogenesis,tryptophanyl-tRNA aminoacylation,mitochondrial matrix,gene expression","."]
["WRAP53","WD repeat containing, antisense to TP53 [Source:HGNC Symbol;Acc:25522]","ENSG00000141499","ENSP00000324203",2,"WD40[2]","family-979","WRAP53",".",".","ncRNA","teloRNA","This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]",".",".",".",".",".",".","GO:0003723,GO:0005697","RNA binding,telomerase holoenzyme complex","GO:0005515,GO:0003723,GO:0005634,GO:0005737,GO:0005730,GO:0015030,GO:0005697,GO:0032203,GO:0051973","protein binding,RNA binding,nucleus,cytoplasm,nucleolus,Cajal body,telomerase holoenzyme complex,telomere formation via telomerase,positive regulation of telomerase activity"," DYSKERATOSIS CONGENITA, AUTOSOMAL RECESSIVE, 3; DKCB3"]
["RSL24D1","ribosomal L24 domain containing 1 [Source:HGNC Symbol;Acc:18479]","ENSG00000137876","ENSP00000454492",1,"Ribosomal_L24e[1]","family-98","RSL24D1",".",".","rRNA","putative rRNA","This gene encodes a protein sharing a low level of sequence similarity with human ribosomal protein L24. Although this gene has been referred to as RPL24, L30, and 60S ribosomal protein L30 isolog in the sequence databases, it is distinct from the human genes officially named RPL24 (which itself has been referred to as ribosomal protein L30) and RPL30. The protein encoded by this gene localizes to the nucleolus and is thought to play a role in the biogenesis of the 60S ribosomal subunit. The precise function of this gene is currently unknown. This gene utilizes alternative polyadenylation signals and has multiple pseudogenes. [provided by RefSeq, Jul 2012",".",".",".",".",".",".","GO:0042254","ribosome biogenesis","GO:0042254,GO:0005730","ribosome biogenesis,nucleolus","."]
["SF3B4","splicing factor 3b, subunit 4, 49kDa [Source:HGNC Symbol;Acc:10771]","ENSG00000143368","ENSP00000391114",2,"RRM_1[2]","family-980","SF3B4",".",".","mRNA","mRNA","This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]","RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0005681,GO:0005689,GO:0006397,GO:0008380,GO:0000398,GO:0000375","RNA binding,spliceosomal complex,U12-type spliceosomal complex,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions","GO:0000166,GO:0003676,GO:0003723,GO:0005515,GO:0005654,GO:0005681,GO:0005689,GO:0010467,GO:0006397,GO:0008380,GO:0000398,GO:0000375","nucleotide binding,nucleic acid binding,RNA binding,protein binding,nucleoplasm,spliceosomal complex,U12-type spliceosomal complex,gene expression,mRNA processing,RNA splicing,mRNA splicing, via spliceosome,RNA splicing, via transesterification reactions"," ACROFACIAL DYSOSTOSIS 1, NAGER TYPE; AFD1"]
["TDRD7","tudor domain containing 7 [Source:HGNC Symbol;Acc:30831]","ENSG00000196116","ENSP00000347444",4,"TUDOR[3],OST-HTH[1]","family-981","TDRD7",".",".","mRNA","mRNA/piRNA  related",21436445,".",".",".",".",".",".","GO:0003729,GO:0043186,GO:0035770,GO:0030529","mRNA binding,P granule,ribonucleoprotein granule,ribonucleoprotein complex","GO:0005515,GO:0003729,GO:0047485,GO:0005737,GO:0005759,GO:0033391,GO:0043186,GO:0035770,GO:0007283,GO:0007281,GO:0002089,GO:0070306,GO:0010608,GO:0030529","protein binding,mRNA binding,protein N-terminus binding,cytoplasm,mitochondrial matrix,chromatoid body,P granule,ribonucleoprotein granule,spermatogenesis,germ cell development,lens morphogenesis in camera-type eye,lens fiber cell differentiation,posttranscriptional regulation of gene expression,ribonucleoprotein complex"," CATARACT 36; CTRCT36"]
["LARP1","La ribonucleoprotein domain family, member 1 [Source:HGNC Symbol;Acc:29531]","ENSG00000155506","ENSP00000336721",1,"La[1]","family-982","LARP1,LARP1B","LARP1","LARP1B[53,59]","mRNA","mRNA",24532714,"RNAbinding","novel",1,1,1,1,"GO:0003723","RNA binding","GO:0003723,GO:0016239","RNA binding,positive regulation of macroautophagy","."]
["LARP1B","La ribonucleoprotein domain family, member 1B [Source:HGNC Symbol;Acc:24704]","ENSG00000138709","ENSP00000422850",1,"La[1]","family-982","LARP1,LARP1B","LARP1","LARP1B[53,59]","mRNA","putative mRNA","by homology","RNAbinding",".",".",1,".",1,"GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0003723,GO:0030529,GO:0019013","RNA binding,ribonucleoprotein complex,viral nucleocapsid","."]
["RPL23A","ribosomal protein L23a [Source:HGNC Symbol;Acc:10317]","ENSG00000198242","ENSP00000389103",2,"Ribosomal_L23[1],Ribosomal_L23eN[1]","family-983","RPL23A",".",".","ribosome","ribosome","established RBP ","ribosomal","RNAbinding",1,1,".",".","GO:0003735,GO:0005840,GO:0006412,GO:0019843,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,rRNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0000166,GO:0005515,GO:0019843,GO:0005634,GO:0005829,GO:0022625,GO:0031932,GO:0008283,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,nucleotide binding,protein binding,rRNA binding,nucleus,cytosol,cytosolic large ribosomal subunit,TORC2 complex,cell proliferation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["BAZ2A","bromodomain adjacent to zinc finger domain, 2A [Source:HGNC Symbol;Acc:962]","ENSG00000076108","ENSP00000446880",7,"MBD[1],WHIM2[1],WHIM3[1],Bromodomain[1],PHD[1],DDT[1],WHIM1[1]","family-984","BAZ2A,BAZ2B","BAZ2A","BAZ2B[34,30]","ncRNA","lincRNA","18600236, 19578370",".",".",".",".",".",".","GO:0003723","RNA binding","GO:0003723,GO:0005515,GO:0008270,GO:0003677,GO:0005634,GO:0005730,GO:0051567,GO:0000183,GO:0034770,GO:0070869,GO:0070933,GO:0016922,GO:0070577,GO:0005677,GO:0033553,GO:0006351,GO:0006355,GO:0006306,GO:0006338,GO:0016575","RNA binding,protein binding,zinc ion binding,DNA binding,nucleus,nucleolus,histone H3-K9 methylation,chromatin silencing at rDNA,histone H4-K20 methylation,heterochromatin assembly involved in chromatin silencing,histone H4 deacetylation,ligand-dependent nuclear receptor binding,histone acetyl-lysine binding,chromatin silencing complex,rDNA heterochromatin,transcription, DNA-templated,regulation of transcription, DNA-dependent,DNA methylation,chromatin remodeling,histone deacetylation","."]
["BAZ2B","bromodomain adjacent to zinc finger domain, 2B [Source:HGNC Symbol;Acc:963]","ENSG00000123636","ENSP00000376533",4,"MBD[1],Bromodomain[1],PHD[1],DDT[1]","family-984","BAZ2A,BAZ2B","BAZ2A","BAZ2B[34,30]","ncRNA","putative lincRNA","by homology",".",".",".",".",".",".",".",".","GO:0005488,GO:0005515,GO:0008270,GO:0003677,GO:0005634,GO:0006351,GO:0006355","binding,protein binding,zinc ion binding,DNA binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent","."]
["EIF3E","eukaryotic translation initiation factor 3, subunit E [Source:HGNC Symbol;Acc:3277]","ENSG00000104408","ENSP00000220849",2,"eIF3_N[1],PCI[1]","family-985","EIF3E",".",".","mRNA","mRNA",17468741,"translationfactor",".",".",1,1,".","GO:0003743,GO:0005852,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0006413,GO:0006412,GO:0000184","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,translational initiation,translation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","GO:0003743,GO:0005852,GO:0005515,GO:0005634,GO:0005737,GO:0016605,GO:0016282,GO:0033290,GO:0001731,GO:0006446,GO:0047485,GO:0005829,GO:0005654,GO:0000785,GO:0006413,GO:0006412,GO:0010467,GO:0044267,GO:0045947,GO:0000184","translation initiation factor activity,eukaryotic translation initiation factor 3 complex,protein binding,nucleus,cytoplasm,PML body,eukaryotic 43S preinitiation complex,eukaryotic 48S preinitiation complex,formation of translation preinitiation complex,regulation of translational initiation,protein N-terminus binding,cytosol,nucleoplasm,chromatin,translational initiation,translation,gene expression,cellular protein metabolic process,negative regulation of translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","."]
["CWC15","CWC15 spliceosome-associated protein homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:26939]","ENSG00000261974","ENSP00000461115",1,"Cwf_Cwc_15[1]","family-986","CWC15",".",".","mRNA","mRNA","by homology, 11991638",".","novel",".",1,".",".","GO:0003723,GO:0005681,GO:0071013,GO:0000398","RNA binding,spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","GO:0003723,GO:0005515,GO:0005634,GO:0005681,GO:0071013,GO:0000398","RNA binding,protein binding,nucleus,spliceosomal complex,catalytic step 2 spliceosome,mRNA splicing, via spliceosome","."]
["TOP1","topoisomerase (DNA) I [Source:HGNC Symbol;Acc:11986]","ENSG00000198900","ENSP00000354522",3,"Topo_C_assoc[1],Topoisom_I[1],Topoisom_I_N[1]","family-987","TOP1,TOP1MT","TOP1","TOP1MT[52,66]","unknown","unknown","12270136, 9659906","candidate mRNA binder","novel",1,1,".",".","GO:0000932","cytoplasmic mRNA processing body","GO:0003917,GO:0005515,GO:0005524,GO:0003677,GO:0003682,GO:0003918,GO:0005737,GO:0005634,GO:0000932,GO:0005694,GO:0005730,GO:0005654,GO:0000228,GO:0043204,GO:0031298,GO:0006260,GO:0006265,GO:0042493,GO:0040016,GO:0006338,GO:0007059,GO:0012501,GO:0019048,GO:0016310","DNA topoisomerase type I activity,protein binding,ATP binding,DNA binding,chromatin binding,DNA topoisomerase type II (ATP-hydrolyzing) activity,cytoplasm,nucleus,cytoplasmic mRNA processing body,chromosome,nucleolus,nucleoplasm,nuclear chromosome,perikaryon,replication fork protection complex,DNA replication,DNA topological change,response to drug,embryonic cleavage,chromatin remodeling,chromosome segregation,programmed cell death,modulation by virus of host morphology or physiology,phosphorylation","."]
["RPL31","ribosomal protein L31 [Source:HGNC Symbol;Acc:10334]","ENSG00000071082","ENSP00000387120",1,"Ribosomal_L31e[1]","family-988","RPL31",".",".","ribosome","ribosome","established RBP ",".","RNAbinding",".",1,1,".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0022625,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","structural constituent of ribosome,ribosome,translation,RNA binding,cytosolic large ribosomal subunit,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0003723,GO:0005829,GO:0022625,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","structural constituent of ribosome,intracellular,ribosome,translation,RNA binding,cytosol,cytosolic large ribosomal subunit,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["SUPT6H","suppressor of Ty 6 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:11470]","ENSG00000109111","ENSP00000319104",8,"S1[1],DLD[1],SH2_2[1],YqgF[1],HTH_44[1],Tex_N[1],HHH_7[1],SPT6_acidic[1]","family-989","SUPT6H",".",".","mRNA","mRNA",24050178,"RNAbinding","RNAbinding",1,1,1,1,"GO:0003723,GO:0006397,GO:0008380,GO:0051028,GO:0050684,GO:0010793","RNA binding,mRNA processing,RNA splicing,mRNA transport,regulation of mRNA processing,regulation of mRNA export from nucleus","GO:0003723,GO:0003700,GO:0005515,GO:0003677,GO:0016788,GO:0042393,GO:0005634,GO:0006351,GO:0006355,GO:0006397,GO:0008380,GO:0051028,GO:0006357,GO:0006338,GO:0006139,GO:0050684,GO:0032968,GO:0032784,GO:0019048,GO:0061086,GO:0045191,GO:0051147,GO:0010793","RNA binding,sequence-specific DNA binding transcription factor activity,protein binding,DNA binding,hydrolase activity, acting on ester bonds,histone binding,nucleus,transcription, DNA-templated,regulation of transcription, DNA-dependent,mRNA processing,RNA splicing,mRNA transport,regulation of transcription from RNA polymerase II promoter,chromatin remodeling,nucleobase-containing compound metabolic process,regulation of mRNA processing,positive regulation of transcription elongation from RNA polymerase II promoter,regulation of DNA-dependent transcription, elongation,modulation by virus of host morphology or physiology,negative regulation of histone H3-K27 methylation,regulation of isotype switching,regulation of muscle cell differentiation,regulation of mRNA export from nucleus","."]
["TST","thiosulfate sulfurtransferase (rhodanese) [Source:HGNC Symbol;Acc:12388]","ENSG00000128311","ENSP00000385828",2,"Rhodanese[2]","family-99","MPST,TST","MPST","TST[56,59]","rRNA","rRNA","This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012",".",".",".",".",".",".","GO:0008097,GO:0035928,GO:0051029","5S rRNA binding,rRNA import into mitochondrion,rRNA transport","GO:0004792,GO:0005743,GO:0008097,GO:0005886,GO:0005739,GO:0005759,GO:0044281,GO:0034641,GO:0000096,GO:0000098,GO:0070221,GO:0009440,GO:0035928,GO:0051029","thiosulfate sulfurtransferase activity,mitochondrial inner membrane,5S rRNA binding,plasma membrane,mitochondrion,mitochondrial matrix,small molecule metabolic process,cellular nitrogen compound metabolic process,sulfur amino acid metabolic process,sulfur amino acid catabolic process,sulfide oxidation, using sulfide:quinone oxidoreductase,cyanate catabolic process,rRNA import into mitochondrion,rRNA transport","."]
["HNRNPU","heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) [Source:HGNC Symbol;Acc:5048]","ENSG00000153187","ENSP00000393151",3,"SAP[1],SPRY[1],AAA_33[1]","family-990","HNRNPU,HNRNPUL2,HNRNPUL1","HNRNPU","HNRNPUL2[38,42],HNRNPUL1[42,41]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0003723,GO:0030529,GO:0071013,GO:0070937,GO:0008380,GO:0000398,GO:0006396,GO:0070934","RNA binding,ribonucleoprotein complex,catalytic step 2 spliceosome,CRD-mediated mRNA stability complex,RNA splicing,mRNA splicing, via spliceosome,RNA processing,CRD-mediated mRNA stabilization","GO:0005515,GO:0005634,GO:0003723,GO:0005524,GO:0003676,GO:0003677,GO:0016301,GO:0009986,GO:0005654,GO:0030529,GO:0071013,GO:0070937,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0070934","protein binding,nucleus,RNA binding,ATP binding,nucleic acid binding,DNA binding,kinase activity,cell surface,nucleoplasm,ribonucleoprotein complex,catalytic step 2 spliceosome,CRD-mediated mRNA stability complex,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,CRD-mediated mRNA stabilization","."]
["HNRNPUL1","heterogeneous nuclear ribonucleoprotein U-like 1 [Source:HGNC Symbol;Acc:17011]","ENSG00000105323","ENSP00000375863",3,"SAP[1],SPRY[1],AAA_33[1]","family-990","HNRNPU,HNRNPUL2,HNRNPUL1","HNRNPU","HNRNPUL2[38,42],HNRNPUL1[42,41]","mRNA","mRNA","established RBP ","RNAbinding","RNAbinding",1,1,".",".","GO:0030529,GO:0003723,GO:0008380,GO:0000398,GO:0006396","ribonucleoprotein complex,RNA binding,RNA splicing,mRNA splicing, via spliceosome,RNA processing","GO:0005515,GO:0030529,GO:0019013,GO:0003723,GO:0019899,GO:0005634,GO:0005654,GO:0006351,GO:0009615,GO:0006355,GO:0010467,GO:0008380,GO:0000398,GO:0006396,GO:0003676","protein binding,ribonucleoprotein complex,viral nucleocapsid,RNA binding,enzyme binding,nucleus,nucleoplasm,transcription, DNA-templated,response to virus,regulation of transcription, DNA-dependent,gene expression,RNA splicing,mRNA splicing, via spliceosome,RNA processing,nucleic acid binding","."]
["HNRNPUL2","heterogeneous nuclear ribonucleoprotein U-like 2 [Source:HGNC Symbol;Acc:25451]","ENSG00000214753","ENSP00000301785",3,"SAP[1],SPRY[1],AAA_33[1]","family-990","HNRNPU,HNRNPUL2,HNRNPUL1","HNRNPU","HNRNPUL2[38,42],HNRNPUL1[42,41]","mRNA","mRNA","established RBP ","RNAbinding","novel",1,1,".",".",".",".","GO:0005515,GO:0005524,GO:0003676,GO:0016301,GO:0005634","protein binding,ATP binding,nucleic acid binding,kinase activity,nucleus","."]
["RPS25","ribosomal protein S25 [Source:HGNC Symbol;Acc:10413]","ENSG00000118181","ENSP00000435096",1,"Ribosomal_S25[1]","family-991","RPS25",".",".","ribosome","ribosome","established RBP ","ribosomal",".",".",1,".",".","GO:0003723,GO:0003735,GO:0022627,GO:0005840,GO:0015935,GO:0000028,GO:0006412,GO:0016070,GO:0016071,GO:0006414,GO:0006413,GO:0000184,GO:0006415","RNA binding,structural constituent of ribosome,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,ribosomal small subunit assembly,translation,RNA metabolic process,mRNA metabolic process,translational elongation,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination","GO:0003723,GO:0003735,GO:0005737,GO:0005829,GO:0005730,GO:0022627,GO:0005840,GO:0015935,GO:0000028,GO:0006412,GO:0016032,GO:0010467,GO:0016070,GO:0016071,GO:0044267,GO:0006614,GO:0006414,GO:0019058,GO:0006413,GO:0000184,GO:0006415,GO:0019083","RNA binding,structural constituent of ribosome,cytoplasm,cytosol,nucleolus,cytosolic small ribosomal subunit,ribosome,small ribosomal subunit,ribosomal small subunit assembly,translation,viral process,gene expression,RNA metabolic process,mRNA metabolic process,cellular protein metabolic process,SRP-dependent cotranslational protein targeting to membrane,translational elongation,viral life cycle,translational initiation,nuclear-transcribed mRNA catabolic process, nonsense-mediated decay,translational termination,viral transcription","."]
["MRPL23","mitochondrial ribosomal protein L23 [Source:HGNC Symbol;Acc:10322]","ENSG00000214026","ENSP00000370930",1,"Ribosomal_L23[1]","family-992","MRPL23",".",".","ribosome","mitochondrial ribosome","established RBP ",".",".",".",".",".",".","GO:0003735,GO:0005840,GO:0006412,GO:0003723,GO:0005762","structural constituent of ribosome,ribosome,translation,RNA binding,mitochondrial large ribosomal subunit","GO:0003735,GO:0005622,GO:0005840,GO:0006412,GO:0000166,GO:0003723,GO:0005762,GO:0005739","structural constituent of ribosome,intracellular,ribosome,translation,nucleotide binding,RNA binding,mitochondrial large ribosomal subunit,mitochondrion","."]
["EIF1AD","eukaryotic translation initiation factor 1A domain containing [Source:HGNC Symbol;Acc:28147]","ENSG00000175376","ENSP00000436644",1,"eIF-1a[1]","family-993","EIF1AD",".",".","mRNA","putative mRNA",10678173,".",".",".",".",".",".","GO:0003723,GO:0003743,GO:0006413","RNA binding,translation initiation factor activity,translational initiation","GO:0003723,GO:0003743,GO:0006413,GO:0005634","RNA binding,translation initiation factor activity,translational initiation,nucleus","."]
["SETX","senataxin [Source:HGNC Symbol;Acc:445]","ENSG00000107290","ENSP00000224140",2,"AAA_11[1],AAA_12[1]","family-994","SETX",".",".","mRNA","putative mRNA","This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008]",".",".",".",".",".",".","GO:0006396","RNA processing","GO:0005524,GO:0003677,GO:0003678,GO:0005634,GO:0005737,GO:0005730,GO:0005654,GO:0006396,GO:0006302,GO:0007623,GO:0008219,GO:0032508,GO:0006369,GO:0005515","ATP binding,DNA binding,DNA helicase activity,nucleus,cytoplasm,nucleolus,nucleoplasm,RNA processing,double-strand break repair,circadian rhythm,cell death,DNA duplex unwinding,termination of RNA polymerase II transcription,protein binding"," AMYOTROPHIC LATERAL SCLEROSIS 4, JUVENILE; ALS4"]
["MARS2","methionyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:25133]","ENSG00000247626","ENSP00000282276",2,"tRNA-synt_1g[1],Anticodon_1[1]","family-995","MARS2",".",".","tRNA","tRNA","established RBP ",".",".",".",".",".",".","GO:0004825,GO:0004812,GO:0006431,GO:0006418","methionine-tRNA ligase activity,aminoacyl-tRNA ligase activity,methionyl-tRNA aminoacylation,tRNA aminoacylation for protein translation","GO:0000166,GO:0005524,GO:0004825,GO:0004812,GO:0005739,GO:0005737,GO:0005759,GO:0010467,GO:0006431,GO:0006418","nucleotide binding,ATP binding,methionine-tRNA ligase activity,aminoacyl-tRNA ligase activity,mitochondrion,cytoplasm,mitochondrial matrix,gene expression,methionyl-tRNA aminoacylation,tRNA aminoacylation for protein translation","."]
["CNOT3","CCR4-NOT transcription complex, subunit 3 [Source:HGNC Symbol;Acc:7879]","ENSG00000088038","ENSP00000383954",2,"Not3[1],NOT2_3_5[1]","family-996","CNOT3",".",".","mRNA","mRNA","established RBP ",".",".",".",".",".",".","GO:0000932,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047","cytoplasmic mRNA processing body,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA","GO:0005634,GO:0006355,GO:0005515,GO:0005737,GO:0005829,GO:0000932,GO:0030014,GO:0006351,GO:0010467,GO:0016070,GO:0016071,GO:0000288,GO:0000289,GO:0006417,GO:0031047,GO:2000036,GO:0001829","nucleus,regulation of transcription, DNA-dependent,protein binding,cytoplasm,cytosol,cytoplasmic mRNA processing body,CCR4-NOT complex,transcription, DNA-templated,gene expression,RNA metabolic process,mRNA metabolic process,nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay,nuclear-transcribed mRNA poly(A) tail shortening,regulation of translation,gene silencing by RNA,regulation of stem cell maintenance,trophectodermal cell differentiation","."]
["MTIF2","mitochondrial translational initiation factor 2 [Source:HGNC Symbol;Acc:7441]","ENSG00000085760","ENSP00000378099",3,"GTP_EFTU_D2[1],IF-2[1],GTP_EFTU[1]","family-997","MTIF2",".",".","tRNA","putative tRNA",12095986,".","novel",".",1,".",".","GO:0003743,GO:0008135,GO:0043024,GO:0006446,GO:0001732,GO:0032790","translation initiation factor activity,translation factor activity, nucleic acid binding,ribosomal small subunit binding,regulation of translational initiation,formation of translation initiation complex,ribosome disassembly","GO:0005525,GO:0003924,GO:0003743,GO:0008135,GO:0043024,GO:0005739,GO:0005622,GO:0007264,GO:0006446,GO:0001732,GO:0032790","GTP binding,GTPase activity,translation initiation factor activity,translation factor activity, nucleic acid binding,ribosomal small subunit binding,mitochondrion,intracellular,small GTPase mediated signal transduction,regulation of translational initiation,formation of translation initiation complex,ribosome disassembly","."]
["JAKMIP1","janus kinase and microtubule interacting protein 1 [Source:HGNC Symbol;Acc:26460]","ENSG00000152969","ENSP00000386711",".",".","family-998","JAKMIP1,JAKMIP2,JAKMIP3","JAKMIP1","JAKMIP2[64,65],JAKMIP3[61,60]","mRNA","mRNA",14718537,".",".",".",".",".",".","GO:0003723,GO:0030529","RNA binding,ribonucleoprotein complex","GO:0019900,GO:0008017,GO:0003723,GO:0019894,GO:0050811,GO:0005737,GO:0019898,GO:0005874,GO:0030529,GO:0015031","kinase binding,microtubule binding,RNA binding,kinesin binding,GABA receptor binding,cytoplasm,extrinsic to membrane,microtubule,ribonucleoprotein complex,protein transport","."]
["FASTKD1","FAST kinase domains 1 [Source:HGNC Symbol;Acc:26150]","ENSG00000138399","ENSP00000400513",3,"FAST_1[1],FAST_2[1],RAP[1]","family-999","FASTKD1",".",".","mRNA","putative mRNA",15501674,"candidate mRNA binder","novel",1,1,".",".",".",".","GO:0004672,GO:0005739,GO:0045333","protein kinase activity,mitochondrion,cellular respiration","."]

{"sheet":"RBP families","index":2,"n_rows":1112,"n_cols":4,"rows_kept":1112,"flags":["formulas_cached_only"]}
["family ID","paralogous family","RNA targets of members","consensus RNA target"]
["family-1","RPS11","ribosome","ribosome"]
["family-10","ERAL1","rRNA","rRNA"]
["family-100","DDX27","rRNA","rRNA"]
["family-1000","DEK","mRNA","mRNA"]
["family-1001","PSMA6","unknown","unknown"]
["family-1002","TRIM45,TRIM56,TRIM71,TRIM3,TRIM2","NA,unknown,ncRNA,NA,NA","ncRNA"]
["family-1003","UPF2","mRNA","mRNA"]
["family-1004","FARS2,FDXACB1","tRNA,tRNA","tRNA"]
["family-1005","ALKBH8,KIAA1456","tRNA,NA","tRNA"]
["family-1006","ZNF579","unknown","unknown"]
["family-1007","POLR1B,POLR3B,POLR2B","NA,NA,mRNA","mRNA"]
["family-1008","WDR12,WDR37","rRNA,NA","rRNA"]
["family-1009","RPF1","rRNA","rRNA"]
["family-101","MRPS34","ribosome","ribosome"]
["family-1010","UBTF","rRNA","rRNA"]
["family-1011","CDC5L","mRNA","mRNA"]
["family-1012","DAZAP1,MSI2,MSI1,TARDBP","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-1013","TRIT1","tRNA","tRNA"]
["family-1014","MRPL36","ribosome","ribosome"]
["family-1015","KPNB1","mRNA","mRNA"]
["family-1016","ZNFX1","unknown","unknown"]
["family-1017","SNRNP27","snRNA","snRNA"]
["family-1018","RBMS1,RBMS2,RBMS3","mRNA,mRNA,mRNA","mRNA"]
["family-1019","LARS2","tRNA","tRNA"]
["family-102","KIAA0020","mRNA","mRNA"]
["family-1020","RBFOX1,RBFOX2,RBFOX3","mRNA,mRNA,mRNA","mRNA"]
["family-1021","CWF19L1,CWF19L2","mRNA,mRNA","mRNA"]
["family-1022","ZC3H15","unknown","unknown"]
["family-1023","LONP1,LONP2","diverse,NA","diverse"]
["family-1024","DBR1","mRNA","mRNA"]
["family-1025","RRP15","rRNA","rRNA"]
["family-1026","L1TD1","mRNA","mRNA"]
["family-1027","NMD3","mRNA","mRNA"]
["family-1028","SRSF10,SRSF12,SRSF8,SRSF2,SRSF12,SRSF8,SRSF2","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-1029","RSL1D1","unknown","unknown"]
["family-103","DAP3","ribosome","ribosome"]
["family-1030","NARS2","tRNA","tRNA"]
["family-1031","RBM25","mRNA","mRNA"]
["family-1032","POLR2E","mRNA","mRNA"]
["family-1033","TOE1","unknown","unknown"]
["family-1034","TSFM","mRNA","mRNA"]
["family-1035","TPR","mRNA","mRNA"]
["family-1036","STAU1,STAU2","mRNA,mRNA","mRNA"]
["family-1037","TRMT1L","tRNA","tRNA"]
["family-1038","METTL3","mRNA","mRNA"]
["family-1039","REXO2","rRNA","rRNA"]
["family-104","MRPL52","ribosome","ribosome"]
["family-1040","WDR3","snoRNA","snoRNA"]
["family-1041","CNOT11","mRNA","mRNA"]
["family-1042","YTHDC1","mRNA","mRNA"]
["family-1043","METTL2A,METTL2B,METTL8,METTL6","tRNA,tRNA,NA,NA","tRNA"]
["family-1044","AKAP8,ZNF326,AKAP8L","mRNA,mRNA,mRNA","mRNA"]
["family-1045","RPS14","ribosome","ribosome"]
["family-1046","ELAVL1,ELAVL2,ELAVL4,ELAVL3","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-1047","PNN","mRNA","mRNA"]
["family-1048","DDX41","mRNA","mRNA"]
["family-1049","TNPO1,TNPO2","mRNA,mRNA","mRNA"]
["family-105","PUSL1","tRNA","tRNA"]
["family-1050","RBM43","mRNA","mRNA"]
["family-1051","ZGPAT","unknown","unknown"]
["family-1052","SCAF11","mRNA","mRNA"]
["family-1053","USP39","snRNA","snRNA"]
["family-1054","RPL38","ribosome","ribosome"]
["family-1055","NARS","tRNA","tRNA"]
["family-1056","RPS16","ribosome","ribosome"]
["family-1057","CLASRP","mRNA","mRNA"]
["family-1058","RPS9","ribosome","ribosome"]
["family-1059","TOP3A,TOP3B","NA,mRNA","mRNA"]
["family-106","NCBP2,NCBP2L","mRNA,mRNA","mRNA"]
["family-1060","SMG9","mRNA","mRNA"]
["family-1061","FTSJ2","rRNA","rRNA"]
["family-1062","DDX56","rRNA","rRNA"]
["family-1063","RBM28","snRNA","snRNA"]
["family-1064","UTP11L","snoRNA","snoRNA"]
["family-1065","MRPS18B","ribosome","ribosome"]
["family-1066","RPL14","ribosome","ribosome"]
["family-1067","RPL37","ribosome","ribosome"]
["family-1068","GEMIN5","snRNA","snRNA"]
["family-1069","MKRN1,MKRN3,MKRN2","mRNA,mRNA,mRNA","mRNA"]
["family-107","NOA1","rRNA","rRNA"]
["family-1070","PINX1","ncRNA","ncRNA"]
["family-1071","HRSP12","unknown","unknown"]
["family-1072","DHX36,DHX30,YTHDC2,DHX9,DHX29,DHX57,TDRD9","mRNA,mRNA,mRNA,ncRNA,mRNA,mRNA,ncRNA","mRNA"]
["family-1073","EIF3G","mRNA","mRNA"]
["family-1074","NOL10","rRNA","rRNA"]
["family-1075","UTP15","snoRNA","snoRNA"]
["family-1076","GATC","tRNA","tRNA"]
["family-1077","TCOF1","rRNA","rRNA"]
["family-1078","NONO,PSPC1,SFPQ","ncRNA,ncRNA,mRNA","mRNA"]
["family-1079","NUDT21","mRNA","mRNA"]
["family-108","MRPL19","ribosome","ribosome"]
["family-1080","URM1","tRNA","tRNA"]
["family-1081","MRPL53","ribosome","ribosome"]
["family-1082","RBM48","mRNA","mRNA"]
["family-1083","REPIN1","unknown","unknown"]
["family-1084","ZC3H12A,ZC3H12B,ZC3H12C,ZC3H12D","ncRNA,unknown,unknown,unknown","ncRNA"]
["family-1085","TRMT5","tRNA","tRNA"]
["family-1086","TRMT61A","tRNA","tRNA"]
["family-1087","PABPN1,PABPN1L","mRNA,mRNA","mRNA"]
["family-1088","GNL1,LSG1","rRNA,rRNA","rRNA"]
["family-1089","EEF1G","tRNA","tRNA"]
["family-109","RBM33","mRNA","mRNA"]
["family-1090","RPP25,RPP25L","ncRNA,ncRNA","ncRNA"]
["family-1091","RPP38","ncRNA","ncRNA"]
["family-1092","GARS","tRNA","tRNA"]
["family-1093","DRG2","mRNA","mRNA"]
["family-1094","TRMU","tRNA","tRNA"]
["family-1095","GNL2","rRNA","rRNA"]
["family-1096","CPSF2","mRNA","mRNA"]
["family-1097","CD3EAP","rRNA","rRNA"]
["family-1098","HDLBP","mRNA","mRNA"]
["family-1099","RDM1","unknown","unknown"]
["family-11","BYSL","rRNA","rRNA"]
["family-110","GEMIN8","snRNA","snRNA"]
["family-1100","XPO5","ncRNA","ncRNA"]
["family-1101","ZNF622","unknown","unknown"]
["family-1102","DZIP1,DZIP1L","mRNA,mRNA","mRNA"]
["family-1103","GSPT1,GSPT2,HBS1L","mRNA,mRNA,mRNA","mRNA"]
["family-1104","EIF2D","tRNA","tRNA"]
["family-1105","METTL1","tRNA","tRNA"]
["family-1106","RNASEH1","diverse","diverse"]
["family-1107","ZNHIT6","snoRNA","snoRNA"]
["family-1108","DARS2","tRNA","tRNA"]
["family-1109","SNRPD2","snRNA","snRNA"]
["family-111","DICER1","ncRNA","ncRNA"]
["family-1110","DNAL4,DYNLL2,DYNLL1","NA,NA,mRNA","mRNA"]
["family-1111","ZNF638","mRNA","mRNA"]
["family-112","SAMD4A,SAMD4B","mRNA,mRNA","mRNA"]
["family-113","RTF1","mRNA","mRNA"]
["family-114","CNOT4","mRNA","mRNA"]
["family-115","PRKRA,TARBP2","ncRNA,mRNA","mRNA"]
["family-116","GLE1","mRNA","mRNA"]
["family-117","EXOSC2","diverse","diverse"]
["family-118","SSU72","mRNA","mRNA"]
["family-119","GTPBP10,MTG2","unknown,NA","unknown"]
["family-12","RPL10A","ribosome","ribosome"]
["family-120","HENMT1","ncRNA","ncRNA"]
["family-121","THOC2","mRNA","mRNA"]
["family-122","ENDOG,EXOG","diverse,diverse","diverse"]
["family-123","ASH1L,SUV39H1,SUV39H2,SETBP1,WHSC1,WHSC1L1","ncRNA,NA,NA,NA,NA,NA","ncRNA"]
["family-124","TRMT10B,TRMT10C,TRMT10A","tRNA,ncRNA,tRNA","tRNA"]
["family-125","MRPL33","ribosome","ribosome"]
["family-126","LARP7,SSB","ncRNA,tRNA","tRNA"]
["family-127","MRPL24","ribosome","ribosome"]
["family-128","RNASEK","diverse","diverse"]
["family-129","PELO","mRNA","mRNA"]
["family-13","QARS","tRNA","tRNA"]
["family-130","IPO4","mRNA","mRNA"]
["family-131","CAPRIN1,CAPRIN2","mRNA,mRNA","mRNA"]
["family-132","PARN,PNLDC1","mRNA,mRNA","mRNA"]
["family-133","TIA1,TIAL1","mRNA,mRNA","mRNA"]
["family-134","CDC40,WDR25","mRNA,NA","mRNA"]
["family-135","ZNF598","mRNA","mRNA"]
["family-136","RCL1,RTCA","rRNA,tRNA","tRNA"]
["family-137","PEBP1,PEBP4,MRPL38","NA,NA,ribosome","ribosome"]
["family-138","ADAT2","tRNA","tRNA"]
["family-139","BOP1","rRNA","rRNA"]
["family-14","U2SURP","snRNA","snRNA"]
["family-140","DUS3L","tRNA","tRNA"]
["family-141","CSTF3","mRNA","mRNA"]
["family-142","SREK1,SRSF11","mRNA,mRNA","mRNA"]
["family-143","POLR1E","rRNA","rRNA"]
["family-144","EXOSC7,EXOSC8,EXOSC9","diverse,diverse,diverse","diverse"]
["family-145","MRPL12","ribosome","ribosome"]
["family-146","RPS28","ribosome","ribosome"]
["family-147","TEFM","mRNA","mRNA"]
["family-148","RPL12","ribosome","ribosome"]
["family-149","ZC3H3","mRNA","mRNA"]
["family-15","EIF6","mRNA","mRNA"]
["family-150","NELFE","mRNA","mRNA"]
["family-151","EIF2B3","mRNA","mRNA"]
["family-152","AICDA,APOBEC2,APOBEC3D,APOBEC3F,APOBEC1,APOBEC3C,APOBEC3B,APOBEC3H,APOBEC3G,APOBEC3A","NA,mRNA,NA,mRNA,mRNA,NA,NA,ncRNA,mRNA,NA","mRNA"]
["family-153","ZC3H7A,ZC3H7B","unknown,unknown","unknown"]
["family-154","NOP9","rRNA","rRNA"]
["family-155","PQBP1","mRNA","mRNA"]
["family-156","PATL1,PATL2","mRNA,mRNA","mRNA"]
["family-157","EDC3","mRNA","mRNA"]
["family-158","WBP4","mRNA","mRNA"]
["family-159","GLTSCR2","rRNA","rRNA"]
["family-16","RPS18","ribosome","ribosome"]
["family-160","ASCC1","unknown","unknown"]
["family-161","EIF5A,EIF5AL1,EIF5A2","mRNA,mRNA,mRNA","mRNA"]
["family-162","MRPL47","ribosome","ribosome"]
["family-163","DAZ1,DAZ3,DAZ4,DAZ2,DAZL,BOLL","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-164","INTS1","snRNA","snRNA"]
["family-165","RPLP1","ribosome","ribosome"]
["family-166","MRPS11","ribosome","ribosome"]
["family-167","WDR43","rRNA","rRNA"]
["family-168","TRMT112","tRNA","tRNA"]
["family-169","PPP1R8","diverse","diverse"]
["family-17","FBXO17,FBXO27,NCCRP1,FBXO6,FBXO44,FBXO2","unknown,NA,NA,NA,NA,NA","unknown"]
["family-170","MTHFSD","mRNA","mRNA"]
["family-171","SON","mRNA","mRNA"]
["family-172","SPATS2,SPATS2L","mRNA,mRNA","mRNA"]
["family-173","MAEL","ncRNA","ncRNA"]
["family-174","RRP1,RRP1B","rRNA,rRNA","rRNA"]
["family-175","PARP11,PARP12,TIPARP,ZC3HAV1,PARP10,PARP14,PARP15","NA,unknown,unknown,ncRNA,NA,NA,NA","ncRNA"]
["family-176","MRPS17","ribosome","ribosome"]
["family-177","U2AF2,UHMK1","mRNA,mRNA","mRNA"]
["family-178","NUP153","diverse","diverse"]
["family-179","CSDE1","mRNA","mRNA"]
["family-18","POLR2L","mRNA","mRNA"]
["family-180","NKRF","unknown","unknown"]
["family-181","MRPL48","ribosome","ribosome"]
["family-182","XRCC6","mRNA","mRNA"]
["family-183","SUPT5H","mRNA","mRNA"]
["family-184","TSR3","rRNA","rRNA"]
["family-185","XRN2","diverse","diverse"]
["family-186","RSRC1","mRNA","mRNA"]
["family-187","TDRD5","ncRNA","ncRNA"]
["family-188","POLR2J,POLR2J2,POLR2J3","mRNA,mRNA,mRNA","mRNA"]
["family-189","SAFB,SAFB2,SLTM","mRNA,mRNA,mRNA","mRNA"]
["family-19","BRIX1","rRNA","rRNA"]
["family-190","POLR2I","mRNA","mRNA"]
["family-191","PWP2","snoRNA","snoRNA"]
["family-192","ELAC2","tRNA","tRNA"]
["family-193","ZCCHC14,ZCCHC2","unknown,unknown","unknown"]
["family-194","LARS","tRNA","tRNA"]
["family-195","MRPL28","ribosome","ribosome"]
["family-196","CNOT1","mRNA","mRNA"]
["family-197","DDX18","rRNA","rRNA"]
["family-198","TSEN15","tRNA","tRNA"]
["family-199","USP10","mRNA","mRNA"]
["family-2","SMNDC1","mRNA","mRNA"]
["family-20","THUMPD2,THUMPD3","tRNA,tRNA","tRNA"]
["family-200","SND1","mRNA","mRNA"]
["family-201","LSM4","snRNA","snRNA"]
["family-202","EIF3M","mRNA","mRNA"]
["family-203","MRPL34","ribosome","ribosome"]
["family-204","SRP72","ncRNA","ncRNA"]
["family-205","SUGP1,SUGP2","mRNA,mRNA","mRNA"]
["family-206","RPS3","ribosome","ribosome"]
["family-207","RPS27A","ribosome","ribosome"]
["family-208","CCAR1,CCAR2","mRNA,mRNA","mRNA"]
["family-209","DDX49","rRNA","rRNA"]
["family-21","MRPL4","ribosome","ribosome"]
["family-210","SFSWAP","mRNA","mRNA"]
["family-211","MRPS12","ribosome","ribosome"]
["family-212","EIF1,EIF1B","mRNA,mRNA","mRNA"]
["family-213","CLP1","mRNA","mRNA"]
["family-214","ZMAT5","snRNA","snRNA"]
["family-215","DDB1,SF3B3","NA,mRNA","mRNA"]
["family-216","PLD6","ncRNA","ncRNA"]
["family-217","QTRT1,QTRTD1","tRNA,tRNA","tRNA"]
["family-218","PIH1D1","snoRNA","snoRNA"]
["family-219","SWT1","mRNA","mRNA"]
["family-22","EXOSC4,EXOSC6","diverse,diverse","diverse"]
["family-220","PTRH1","tRNA","tRNA"]
["family-221","INTS8","snRNA","snRNA"]
["family-222","EXOSC10","diverse","diverse"]
["family-223","CASC3","mRNA","mRNA"]
["family-224","GTF3A","rRNA","rRNA"]
["family-225","MRPL54","ribosome","ribosome"]
["family-226","GTPBP3","tRNA","tRNA"]
["family-227","UBA1,UBA7,UBA6","mRNA,NA,NA","mRNA"]
["family-228","LSM12","mRNA","mRNA"]
["family-229","HINT3","tRNA","tRNA"]
["family-23","CCDC59","unknown","unknown"]
["family-230","POLDIP3","mRNA","mRNA"]
["family-231","RPL32","ribosome","ribosome"]
["family-232","AZGP1,HLA-F,HLA-C,HLA-E,HLA-B,HLA-G,HLA-A,MR1,FCGRT,HFE","unknown,NA,NA,NA,NA,NA,NA,NA,NA,NA","unknown"]
["family-233","EMG1","rRNA","rRNA"]
["family-234","C17orf85","unknown","unknown"]
["family-235","NYNRIN,N4BP1,KHNYN","unknown,unknown,mRNA","mRNA"]
["family-236","NOP2,NSUN3,NSUN6,NSUN4","rRNA,unknown,unknown,rRNA","rRNA"]
["family-237","PAN2","mRNA","mRNA"]
["family-238","ZCCHC9","unknown","unknown"]
["family-239","RRP9","snoRNA","snoRNA"]
["family-24","TNRC6A,TNRC6B,TNRC6C","mRNA,mRNA,mRNA","mRNA"]
["family-240","RP9","snRNA","snRNA"]
["family-241","MRPL15","ribosome","ribosome"]
["family-242","NGDN","mRNA","mRNA"]
["family-243","LSM10","snRNA","snRNA"]
["family-244","PUS1","tRNA","tRNA"]
["family-245","MAK16","rRNA","rRNA"]
["family-246","RPS13","ribosome","ribosome"]
["family-247","ASCC3,SNRNP200","NA,snRNA","snRNA"]
["family-248","PRDX1,PRDX2,PRDX4,PRDX3","mRNA,NA,NA,NA","mRNA"]
["family-249","TSN","tRNA","tRNA"]
["family-25","NUFIP2","mRNA","mRNA"]
["family-250","RBM19","rRNA","rRNA"]
["family-251","TDRKH","ncRNA","ncRNA"]
["family-252","NOP58","snoRNA","snoRNA"]
["family-253","RBM10,RBM5,RBM6","mRNA,mRNA,mRNA","mRNA"]
["family-254","RBM44","mRNA","mRNA"]
["family-255","OAS1,OAS3,OAS2,OASL","ncRNA,ncRNA,ncRNA,ncRNA","ncRNA"]
["family-256","SF3A3","snRNA","snRNA"]
["family-257","NOC3L","rRNA","rRNA"]
["family-258","HNRNPM,MYEF2","mRNA,mRNA","mRNA"]
["family-259","C11orf68","unknown","unknown"]
["family-26","MRPL10","ribosome","ribosome"]
["family-260","RNASE10","unknown","unknown"]
["family-261","CALR,CALR3,CANX,CLGN","mRNA,unknown,unknown,NA","mRNA"]
["family-262","RPP14","ncRNA","ncRNA"]
["family-263","RPS8","ribosome","ribosome"]
["family-264","PDCD7","snRNA","snRNA"]
["family-265","RPS19BP1","unknown","unknown"]
["family-266","TRMT6","tRNA","tRNA"]
["family-267","RPL4","ribosome","ribosome"]
["family-268","PRPF3","snRNA","snRNA"]
["family-269","RARS,RARS2","tRNA,tRNA","tRNA"]
["family-27","APOBEC4","mRNA","mRNA"]
["family-270","ZCCHC24","unknown","unknown"]
["family-271","RPS21","ribosome","ribosome"]
["family-272","DDX24","rRNA","rRNA"]
["family-273","RTCB","tRNA","tRNA"]
["family-274","MBNL1,MBNL2,MBNL3","mRNA,mRNA,mRNA","mRNA"]
["family-275","ALYREF","mRNA","mRNA"]
["family-276","LSMD1","mRNA","mRNA"]
["family-277","PUS7,PUS7L","rRNA,rRNA","rRNA"]
["family-278","MRPS24","ribosome","ribosome"]
["family-279","RBBP6","mRNA","mRNA"]
["family-28","RPL19","ribosome","ribosome"]
["family-280","NOL3","mRNA","mRNA"]
["family-281","RPS27,RPS27L","ribosome,ribosome","ribosome"]
["family-282","MURC,PTRF,SDPR,PRKCDBP","NA,rRNA,NA,NA","rRNA"]
["family-283","MRPS18A","ribosome","ribosome"]
["family-284","SLBP","mRNA","mRNA"]
["family-285","EARS2","tRNA","tRNA"]
["family-286","SMAD1,SMAD7,SMAD6,SMAD4,SMAD5,SMAD9,SMAD2,SMAD3","ncRNA,ncRNA,ncRNA,ncRNA,ncRNA,ncRNA,ncRNA,ncRNA","ncRNA"]
["family-287","PRPF39","snRNA","snRNA"]
["family-288","SRP68","ncRNA","ncRNA"]
["family-289","ADAD1,ADAD2,ADAR,ADAT1,ADARB1,ADARB2","mRNA,mRNA,mRNA,tRNA,mRNA,mRNA","mRNA"]
["family-29","CLK1,CLK4,CLK2,CLK3,PRPF4B","mRNA,mRNA,mRNA,mRNA,snRNA","mRNA"]
["family-290","LSM3","snRNA","snRNA"]
["family-291","FAM46A,FAM46B,FAM46D,FAM46C","unknown,NA,NA,NA","unknown"]
["family-292","CRYZ,VAT1L,TP53I3,VAT1,ZADH2","mRNA,NA,NA,NA,NA","mRNA"]
["family-293","KIN","snRNA","snRNA"]
["family-294","RPS2","ribosome","ribosome"]
["family-295","DUS4L","tRNA","tRNA"]
["family-296","EIF4A1,EIF4A2,EIF4A3","mRNA,mRNA,mRNA","mRNA"]
["family-297","IGF2BP1,IGF2BP3,IGF2BP2","mRNA,mRNA,mRNA","mRNA"]
["family-298","UBAP2,UBAP2L","mRNA,mRNA","mRNA"]
["family-299","SNRPE","snRNA","snRNA"]
["family-3","EIF2B5","mRNA","mRNA"]
["family-30","CRNKL1","mRNA","mRNA"]
["family-300","POLRMT","mRNA","mRNA"]
["family-301","METTL10","tRNA","tRNA"]
["family-302","MRPL41","ribosome","ribosome"]
["family-303","MRPS7","ribosome","ribosome"]
["family-304","NSUN5,NSUN7","rRNA,rRNA","rRNA"]
["family-305","MTG1","rRNA","rRNA"]
["family-306","MRPS28","ribosome","ribosome"]
["family-307","TDRD10","unknown","unknown"]
["family-308","RPUSD1","tRNA","tRNA"]
["family-309","NHP2","snoRNA","snoRNA"]
["family-31","XAB2","mRNA","mRNA"]
["family-310","FAU","ribosome","ribosome"]
["family-311","RRP36","rRNA","rRNA"]
["family-312","GRWD1","rRNA","rRNA"]
["family-313","ENDOV","tRNA","tRNA"]
["family-314","VARSL","tRNA","tRNA"]
["family-315","MRRF","ribosome","ribosome"]
["family-316","MTFMT","tRNA","tRNA"]
["family-317","C12orf65","mRNA","mRNA"]
["family-318","MRTO4","mRNA","mRNA"]
["family-319","RBM26,RBM27","mRNA,mRNA","mRNA"]
["family-32","DIS3,DIS3L,DIS3L2","diverse,diverse,diverse","diverse"]
["family-320","C1QBP","mRNA","mRNA"]
["family-321","SUB1","mRNA","mRNA"]
["family-322","MRPS33","ribosome","ribosome"]
["family-323","PRPF6","snRNA","snRNA"]
["family-324","SMG8","mRNA","mRNA"]
["family-325","PSTK","tRNA","tRNA"]
["family-326","GAPDH,GAPDHS","mRNA,NA","mRNA"]
["family-327","IPO13,TNPO3","mRNA,mRNA","mRNA"]
["family-328","MOV10,MOV10L1","mRNA,mRNA","mRNA"]
["family-329","PARP1,PARP2,PARP3","mRNA,NA,NA","mRNA"]
["family-33","MRPS35","ribosome","ribosome"]
["family-330","GPKOW","unknown","unknown"]
["family-331","SETD1A,SETD1B","ncRNA,ncRNA","ncRNA"]
["family-332","SF3A2","snRNA","snRNA"]
["family-333","AFF1,AFF4,AFF2,AFF3","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-334","PARK7","mRNA","mRNA"]
["family-335","C6orf52,TRNAU1AP","NA,tRNA","tRNA"]
["family-336","SRBD1","unknown","unknown"]
["family-337","EIF3D","mRNA","mRNA"]
["family-338","NOP10","snoRNA","snoRNA"]
["family-339","WARS","tRNA","tRNA"]
["family-34","MATR3","mRNA","mRNA"]
["family-340","SNRPD1","snRNA","snRNA"]
["family-341","SNRPC","snRNA","snRNA"]
["family-342","FMR1,FXR2,FXR1","mRNA,mRNA,mRNA","mRNA"]
["family-343","MEPCE","ncRNA","ncRNA"]
["family-344","KAT5,KAT7,KAT6B,KAT8,KAT6A","NA,NA,NA,ncRNA,NA","ncRNA"]
["family-345","CIRBP,RBM3","mRNA,mRNA","mRNA"]
["family-346","CNOT7,CNOT8","mRNA,mRNA","mRNA"]
["family-347","A1CF,RBM47,DND1,RBM46,SYNCRIP,HNRNPR","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-348","ABCE1","ncRNA","ncRNA"]
["family-349","GPATCH4","unknown","unknown"]
["family-35","PAIP1","mRNA","mRNA"]
["family-350","RBM20","mRNA","mRNA"]
["family-351","GNL3,GNL3L","rRNA,rRNA","rRNA"]
["family-352","FAM120A,FAM120C,FAM120B","mRNA,unknown,unknown","mRNA"]
["family-353","KHDC1,KHDC1L","mRNA,mRNA","mRNA"]
["family-354","RPL10,RPL10L","ribosome,ribosome","ribosome"]
["family-355","EIF2S1","tRNA","tRNA"]
["family-356","MRPL20","ribosome","ribosome"]
["family-357","EPRS","tRNA","tRNA"]
["family-358","DDX58,IFIH1,DHX58","ncRNA,ncRNA,ncRNA","ncRNA"]
["family-359","CDK5RAP1,CDKAL1","tRNA,NA","tRNA"]
["family-36","HABP4,SERBP1","mRNA,mRNA","mRNA"]
["family-360","METTL5","unknown","unknown"]
["family-361","ZCCHC7","diverse","diverse"]
["family-362","WDR36","rRNA","rRNA"]
["family-363","CCDC86","unknown","unknown"]
["family-364","C2orf15,MRPL30,MRPL30","rRNA,ribosome,ribosome","ribosome"]
["family-365","RPS26","ribosome","ribosome"]
["family-366","TEX13A,TEX13B","mRNA,NA","mRNA"]
["family-367","BARD1","ncRNA","ncRNA"]
["family-368","XPO4","mRNA","mRNA"]
["family-369","RUVBL1","mRNA","mRNA"]
["family-37","IMP4","snoRNA","snoRNA"]
["family-370","DDX52","rRNA","rRNA"]
["family-371","THOC1","mRNA","mRNA"]
["family-372","TRPT1","tRNA","tRNA"]
["family-373","NHP2L1","snRNA","snRNA"]
["family-374","EIF2B2","mRNA","mRNA"]
["family-375","RNF113A,RNF113B","snRNA,snRNA","snRNA"]
["family-376","INTS10","snRNA","snRNA"]
["family-377","LENG9","unknown","unknown"]
["family-378","RPS29","ribosome","ribosome"]
["family-379","NOP16","rRNA","rRNA"]
["family-38","U2AF1,U2AF1L4","mRNA,mRNA","mRNA"]
["family-380","IPO5,RANBP6","mRNA,mRNA","mRNA"]
["family-381","THOC7","mRNA","mRNA"]
["family-382","DNMT3A,DNMT3L,DNMT3B","NA,NA,diverse","diverse"]
["family-383","GFM1","mRNA","mRNA"]
["family-384","RNASE9","unknown","unknown"]
["family-385","PLRG1","mRNA","mRNA"]
["family-386","REXO1","rRNA","rRNA"]
["family-387","ZC3HAV1L","unknown","unknown"]
["family-388","LSM14A,LSM14B","mRNA,mRNA","mRNA"]
["family-389","LUZP4","mRNA","mRNA"]
["family-39","TDRD15,TDRD6","unknown,ncRNA","ncRNA"]
["family-390","MRPS22","ribosome","ribosome"]
["family-391","EEF1B2,EEF1D","tRNA,tRNA","tRNA"]
["family-392","SIDT1,SIDT2","ncRNA,ncRNA","ncRNA"]
["family-393","TRMT44","tRNA","tRNA"]
["family-394","GPATCH8,ZNF804B,ZNF804A","unknown,NA,NA","unknown"]
["family-395","WDR4","tRNA","tRNA"]
["family-396","SLIRP","ncRNA","ncRNA"]
["family-397","ATXN1,ATXN1L","mRNA,mRNA","mRNA"]
["family-398","YTHDF1,YTHDF3,YTHDF2","mRNA,mRNA,mRNA","mRNA"]
["family-399","LRPPRC","mRNA","mRNA"]
["family-4","TFIP11","mRNA","mRNA"]
["family-40","ILF2,STRBP,ILF3","mRNA,mRNA,mRNA","mRNA"]
["family-400","TCERG1,TCERG1L","mRNA,NA","mRNA"]
["family-401","NXF1,NXF3,NXF2B,NXF5,NXF2","mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-402","ZRSR1,ZRSR2","mRNA,mRNA","mRNA"]
["family-403","MRPL35","ribosome","ribosome"]
["family-404","RRS1","rRNA","rRNA"]
["family-405","PRKDC","mRNA","mRNA"]
["family-406","NOC2L","rRNA","rRNA"]
["family-407","MTIF3","mRNA","mRNA"]
["family-408","NOL11","rRNA","rRNA"]
["family-409","EXOSC3","diverse","diverse"]
["family-41","PNPT1","diverse","diverse"]
["family-410","TSNAX","tRNA","tRNA"]
["family-411","RIOK1,RIOK3","rRNA,rRNA","rRNA"]
["family-412","PIWIL1,PIWIL2,PIWIL3,PIWIL4","ncRNA,ncRNA,ncRNA,ncRNA","ncRNA"]
["family-413","PEG10,ZCCHC5,ZCCHC16","unknown,unknown,NA","unknown"]
["family-414","POP7","ncRNA","ncRNA"]
["family-415","FASTK,FASTKD3,TBRG4","mRNA,mRNA,mRNA","mRNA"]
["family-416","TRMT13","tRNA","tRNA"]
["family-417","ACO1,IREB2","mRNA,mRNA","mRNA"]
["family-418","ZCCHC3","unknown","unknown"]
["family-419","SNUPN","snRNA","snRNA"]
["family-42","PTRHD1","tRNA","tRNA"]
["family-420","HARS,HARS2","tRNA,tRNA","tRNA"]
["family-421","HNRNPK,PCBP3,PCBP4,PCBP2,PCBP1","mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-422","AQR","mRNA","mRNA"]
["family-423","ICT1","tRNA","tRNA"]
["family-424","UNK,UNKL","unknown,unknown","unknown"]
["family-425","CEBPZ","rRNA","rRNA"]
["family-426","MRPS9","ribosome","ribosome"]
["family-427","THG1L","tRNA","tRNA"]
["family-428","CNBP,ZCCHC13","mRNA,mRNA","mRNA"]
["family-429","SRRT","ncRNA","ncRNA"]
["family-43","CD2BP2","snRNA","snRNA"]
["family-430","SNRPG","snRNA","snRNA"]
["family-431","APTX","diverse","diverse"]
["family-432","RPL17","ribosome","ribosome"]
["family-433","BMS1","rRNA","rRNA"]
["family-434","SARS,SARS2","tRNA,tRNA","tRNA"]
["family-435","PAIP2,PAIP2B","mRNA,mRNA","mRNA"]
["family-436","GEMIN4","snRNA","snRNA"]
["family-437","PNRC1,PNRC2,PNRC2","NA,mRNA,mRNA","mRNA"]
["family-438","FASTKD2","mRNA","mRNA"]
["family-439","GEMIN6","snRNA","snRNA"]
["family-44","DDX20,DDX39B,DDX39A","snRNA,mRNA,mRNA","mRNA"]
["family-440","DHX37","snoRNA","snoRNA"]
["family-441","ZMAT1,KRCC1,ZNF346,ZMAT4","NA,NA,unknown,NA","unknown"]
["family-442","MRPL50","ribosome","ribosome"]
["family-443","ANG,RNASE7,RNASE6,RNASE8,RNASE3,RNASE4,RNASE1,RNASE2","diverse,diverse,diverse,diverse,diverse,diverse,diverse,diverse","diverse"]
["family-444","DNAH1,DNAH17,DNAH9,DYNC1H1,DNAH11,DYNC2H1,DNAH8,DNAH10,DNAH5,DNAH3,DNAH7,DNAH2,DNAH6","NA,NA,NA,mRNA,NA,NA,NA,NA,NA,NA,NA,NA,NA","mRNA"]
["family-445","FTSJ3","rRNA","rRNA"]
["family-446","SF3B2","mRNA","mRNA"]
["family-447","CTU2","tRNA","tRNA"]
["family-448","XPOT","tRNA","tRNA"]
["family-449","RBMX,RBMY1D,RBMY1J,RBMXL1,RBMY1A1,RBMXL2,RBMY1B,RBMY1F,RBMY1E,RBMXL3","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-45","PPP1R10,PRR3","unknown,unknown","unknown"]
["family-450","DKC1","snoRNA","snoRNA"]
["family-451","MRPL17","ribosome","ribosome"]
["family-452","TRA2A,TRA2B","mRNA,mRNA","mRNA"]
["family-453","RPL26,RPL26L1","ribosome,ribosome","ribosome"]
["family-454","AUH,ECHDC3,ECHDC2,ECHS1,ECH1","mRNA,NA,NA,NA,NA","mRNA"]
["family-455","EIF3C,EIF3CL","mRNA,mRNA","mRNA"]
["family-456","SCAF4,SCAF8","mRNA,mRNA","mRNA"]
["family-457","EEF2K","mRNA","mRNA"]
["family-458","RPL6","ribosome","ribosome"]
["family-459","MRPL11","ribosome","ribosome"]
["family-46","G3BP1,G3BP2","mRNA,mRNA","mRNA"]
["family-460","MRPS26","ribosome","ribosome"]
["family-461","SF3B5","mRNA","mRNA"]
["family-462","DHX34","mRNA","mRNA"]
["family-463","UTP23","snoRNA","snoRNA"]
["family-464","SNRNP48","snRNA","snRNA"]
["family-465","PRPF38B","snRNA","snRNA"]
["family-466","HEXIM1,HEXIM2","ncRNA,ncRNA","ncRNA"]
["family-467","SRRM2,SRRM3","mRNA,mRNA","mRNA"]
["family-468","PIH1D3","unknown","unknown"]
["family-469","DHX38,DHX40","mRNA,mRNA","mRNA"]
["family-47","TRMT61B","tRNA","tRNA"]
["family-470","CARHSP1,CSDC2","mRNA,mRNA","mRNA"]
["family-471","POP4","ncRNA","ncRNA"]
["family-472","LARP6","mRNA","mRNA"]
["family-473","RNPC3","snRNA","snRNA"]
["family-474","RPL30","ribosome","ribosome"]
["family-475","RUVBL2","mRNA","mRNA"]
["family-476","DRG1","mRNA","mRNA"]
["family-477","TRIM25,TRIM16,TRIM16L,TRIM47,TRIM65","mRNA,NA,NA,NA,NA","mRNA"]
["family-478","RQCD1","mRNA","mRNA"]
["family-479","MRPS18C","ribosome","ribosome"]
["family-48","MRPL45","ribosome","ribosome"]
["family-480","RPLP2","ribosome","ribosome"]
["family-481","SRP19","ncRNA","ncRNA"]
["family-482","RPS24","ribosome","ribosome"]
["family-483","AKAP17A","mRNA","mRNA"]
["family-484","NXT1,NXT2","mRNA,mRNA","mRNA"]
["family-485","MRPL9","ribosome","ribosome"]
["family-486","RPL27","ribosome","ribosome"]
["family-487","RPL24","ribosome","ribosome"]
["family-488","CNOT10","mRNA","mRNA"]
["family-489","ABT1","mRNA","mRNA"]
["family-49","DDX19A,DDX19B,DDX25","mRNA,mRNA,mRNA","mRNA"]
["family-490","MRPS30","ribosome","ribosome"]
["family-491","SMG1","mRNA","mRNA"]
["family-492","EXOSC5","diverse","diverse"]
["family-493","AIMP2","tRNA","tRNA"]
["family-494","BZW1,BZW2","mRNA,mRNA","mRNA"]
["family-495","PARS2","tRNA","tRNA"]
["family-496","INTS12","snRNA","snRNA"]
["family-497","EIF3H","mRNA","mRNA"]
["family-498","SKIV2L","mRNA","mRNA"]
["family-499","RC3H1,RC3H2","mRNA,mRNA","mRNA"]
["family-5","ZFP36,ZFP36L2,ZFP36L1","mRNA,mRNA,mRNA","mRNA"]
["family-50","ANKHD1,ANKRD17","unknown,unknown","unknown"]
["family-500","HELZ2,UPF1","mRNA,mRNA","mRNA"]
["family-501","DROSHA","ncRNA","ncRNA"]
["family-502","MRPL37","ribosome","ribosome"]
["family-503","PUS10","tRNA","tRNA"]
["family-504","NUDT16,NUDT16L1","snoRNA,snoRNA","snoRNA"]
["family-505","TRMT11","tRNA","tRNA"]
["family-506","PET112","tRNA","tRNA"]
["family-507","NUFIP1","snoRNA","snoRNA"]
["family-508","PURA,PURB,PURG","mRNA,mRNA,mRNA","mRNA"]
["family-509","ZRANB2","mRNA","mRNA"]
["family-51","THOC5","mRNA","mRNA"]
["family-510","TSEN54","tRNA","tRNA"]
["family-511","SRP9","ncRNA","ncRNA"]
["family-512","PIN4","rRNA","rRNA"]
["family-513","ZC3H14","mRNA","mRNA"]
["family-514","CNOT2","mRNA","mRNA"]
["family-515","TARBP1","mRNA","mRNA"]
["family-516","AGO1,AGO2,AGO3,AGO4","ncRNA,ncRNA,ncRNA,ncRNA","ncRNA"]
["family-517","LARP4,LARP4B","mRNA,mRNA","mRNA"]
["family-518","SNW1","mRNA","mRNA"]
["family-519","EZH1,EZH2","NA,ncRNA","ncRNA"]
["family-52","EIF3B","mRNA","mRNA"]
["family-520","RPP30","ncRNA","ncRNA"]
["family-521","ZMAT3","ncRNA","ncRNA"]
["family-522","PTGES3,PTGES3L","ncRNA,NA","ncRNA"]
["family-523","KARS","tRNA","tRNA"]
["family-524","RAN","mRNA","mRNA"]
["family-525","SNRPA,SNRPB2","snRNA,snRNA","snRNA"]
["family-526","HEATR1","snoRNA","snoRNA"]
["family-527","AARSD1,PTGES3L-AARSD1","tRNA,tRNA","tRNA"]
["family-528","CPSF3,CPSF3L","mRNA,mRNA","mRNA"]
["family-529","CWC25","mRNA","mRNA"]
["family-53","RPS5","ribosome","ribosome"]
["family-530","POLR2D","mRNA","mRNA"]
["family-531","C9orf114","unknown","unknown"]
["family-532","MRPL44","ribosome","ribosome"]
["family-533","ETF1","mRNA","mRNA"]
["family-534","GAR1","snoRNA","snoRNA"]
["family-535","MVP","ncRNA","ncRNA"]
["family-536","RPF2","rRNA","rRNA"]
["family-537","ZC3H18","unknown","unknown"]
["family-538","INTS5","snRNA","snRNA"]
["family-539","INTS3","snRNA","snRNA"]
["family-54","LSM6,SNRPF","snRNA,snRNA","snRNA"]
["family-540","MTPAP,TUT1","mRNA,snRNA","mRNA"]
["family-541","EIF2AK1,EIF2AK3,EIF2AK2,EIF2AK4","mRNA,mRNA,ncRNA,tRNA","mRNA"]
["family-542","MRPL22","ribosome","ribosome"]
["family-543","PES1","rRNA","rRNA"]
["family-544","LSM7","snRNA","snRNA"]
["family-545","PAPD4,ZCCHC6,ZCCHC11","mRNA,ncRNA,ncRNA","ncRNA"]
["family-546","KHDRBS1,KHDRBS2,KHDRBS3,QKI,SF1","mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-547","LRRC47","unknown","unknown"]
["family-548","ISY1","mRNA","mRNA"]
["family-549","SRRM1","mRNA","mRNA"]
["family-55","IPO9","mRNA","mRNA"]
["family-550","MTRF1,MTRF1L","mRNA,mRNA","mRNA"]
["family-551","WIBG","mRNA","mRNA"]
["family-552","PPAN","mRNA","mRNA"]
["family-553","FUBP1,KHSRP,FUBP3","mRNA,mRNA,mRNA","mRNA"]
["family-554","CHTOP","mRNA","mRNA"]
["family-555","PTCD2","mRNA","mRNA"]
["family-556","POLR2A,POLR3A","mRNA,NA","mRNA"]
["family-557","MRPL43","ribosome","ribosome"]
["family-558","DDX55","rRNA","rRNA"]
["family-559","RPS15","ribosome","ribosome"]
["family-56","CPSF4,CPSF4L","mRNA,mRNA","mRNA"]
["family-560","CSTF2,CSTF2T","mRNA,mRNA","mRNA"]
["family-561","RAVER1,RAVER2","mRNA,mRNA","mRNA"]
["family-562","EIF1AX,EIF1AY","mRNA,mRNA","mRNA"]
["family-563","DALRD3","tRNA","tRNA"]
["family-564","NSUN2","tRNA","tRNA"]
["family-565","URB2","rRNA","rRNA"]
["family-566","PHAX","snRNA","snRNA"]
["family-567","PPARGC1A,PPARGC1B,PPRC1","unknown,unknown,mRNA","mRNA"]
["family-568","PHF5A","mRNA","mRNA"]
["family-569","MCTS1","unknown","unknown"]
["family-57","RRP7A","rRNA","rRNA"]
["family-570","DGCR8","ncRNA","ncRNA"]
["family-571","ZC3H13","unknown","unknown"]
["family-572","UPF3A,UPF3B","mRNA,mRNA","mRNA"]
["family-573","RBM24,RBM38","mRNA,mRNA","mRNA"]
["family-574","THOC3","mRNA","mRNA"]
["family-575","IGHMBP2","tRNA","tRNA"]
["family-576","PAPD5,PAPD7","diverse,diverse","diverse"]
["family-577","GFM2","mRNA","mRNA"]
["family-578","PHRF1","mRNA","mRNA"]
["family-579","VARS,VARS2","tRNA,tRNA","tRNA"]
["family-58","MRPL1","ribosome","ribosome"]
["family-580","INTS7","snRNA","snRNA"]
["family-581","ATXN2,ATXN2L","mRNA,mRNA","mRNA"]
["family-582","PPIB,PPWD1,PPIL1,CWC27,PPIL3,PPIC,PPIL4,PPIL2,PPIH","NA,mRNA,NA,mRNA,mRNA,NA,mRNA,NA,mRNA","mRNA"]
["family-583","NUTF2","mRNA","mRNA"]
["family-584","MRPL18","ribosome","ribosome"]
["family-585","LSM11","snRNA","snRNA"]
["family-586","AARS,AARS2","tRNA,tRNA","tRNA"]
["family-587","CTIF,MIF4GD","mRNA,mRNA","mRNA"]
["family-588","C9orf129","unknown","unknown"]
["family-589","LUC7L,LUC7L2,LUC7L3","mRNA,mRNA,mRNA","mRNA"]
["family-59","DUS2","tRNA","tRNA"]
["family-590","RNF17,TDRD1","mRNA,ncRNA","mRNA"]
["family-591","MRPS10","ribosome","ribosome"]
["family-592","FAM103A1","mRNA","mRNA"]
["family-593","ENOX1,ENOX2","mRNA,mRNA","mRNA"]
["family-594","RBPMS,RBPMS2","mRNA,mRNA","mRNA"]
["family-595","NIP7","rRNA","rRNA"]
["family-596","RPL3,RPL3L","ribosome,ribosome","ribosome"]
["family-597","RNASE11,RNASE12","unknown,unknown","unknown"]
["family-598","RPLP0","ribosome","ribosome"]
["family-599","RBM34","mRNA","mRNA"]
["family-6","CMTR2","mRNA","mRNA"]
["family-60","ENDOU","snoRNA","snoRNA"]
["family-600","PUM1,PUM2","mRNA,mRNA","mRNA"]
["family-601","HSPBAP1,HIF1AN,TYW5","NA,NA,tRNA","tRNA"]
["family-602","TYW3","tRNA","tRNA"]
["family-603","TRMT1","tRNA","tRNA"]
["family-604","BUB3,RAE1","NA,mRNA","mRNA"]
["family-605","SLU7","mRNA","mRNA"]
["family-606","EIF2B4","mRNA","mRNA"]
["family-607","EIF5B","tRNA","tRNA"]
["family-608","GPATCH1","mRNA","mRNA"]
["family-609","RPL36","ribosome","ribosome"]
["family-61","EEF1A1,EEF1A2","tRNA,tRNA","tRNA"]
["family-610","RRP8","rRNA","rRNA"]
["family-611","UBA52,UBB,ZFAND4,UBC,UBBP4","ribosome,NA,NA,NA,NA","ribosome"]
["family-612","ARPP21,R3HDM2,R3HDM1","NA,unknown,unknown","unknown"]
["family-613","METAP2,PA2G4","NA,rRNA","rRNA"]
["family-614","AAR2","snRNA","snRNA"]
["family-615","ERI1,ERI2,ERI3","rRNA,unknown,unknown","rRNA"]
["family-616","NIFK","rRNA","rRNA"]
["family-617","METTL14","mRNA","mRNA"]
["family-618","MRPL32","ribosome","ribosome"]
["family-619","CPSF6,CPSF7","mRNA,mRNA","mRNA"]
["family-62","RPL7A","ribosome","ribosome"]
["family-620","WDR46","snoRNA","snoRNA"]
["family-621","SRP14","ncRNA","ncRNA"]
["family-622","TFAM","mRNA","mRNA"]
["family-623","CMSS1","rRNA","rRNA"]
["family-624","XPO6","mRNA","mRNA"]
["family-625","EXOSC1","diverse","diverse"]
["family-626","BTRC,WDR86,ZNF106,FBXW11,FBXW2,FBXW7","NA,NA,unknown,NA,NA,NA","unknown"]
["family-627","UTP14A,UTP14C","snoRNA,snoRNA","snoRNA"]
["family-628","TRUB1,TRUB2","tRNA,tRNA","tRNA"]
["family-629","PRIM1","diverse","diverse"]
["family-63","PTCD3","mRNA","mRNA"]
["family-630","HNRNPA0,HNRNPA3,HNRNPA1L2,HNRNPA1,HNRNPA2B1,HNRNPD,HNRNPAB,HNRNPDL","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-631","RANBP2,RGPD6,RGPD5,RGPD3,RGPD8,RGPD1,RGPD4,RGPD2","mRNA,NA,NA,NA,NA,NA,NA,NA","mRNA"]
["family-632","RPL7,RPL7L1","ribosome,ribosome","ribosome"]
["family-633","RNASE13","unknown","unknown"]
["family-634","RPS6","ribosome","ribosome"]
["family-635","MRPL3","ribosome","ribosome"]
["family-636","DDX28,DDX47","rRNA,rRNA","rRNA"]
["family-637","RNASEH2C","diverse","diverse"]
["family-638","TFB2M","rRNA","rRNA"]
["family-639","TEP1","ncRNA","ncRNA"]
["family-64","NOC4L","rRNA","rRNA"]
["family-640","CPSF1","mRNA","mRNA"]
["family-641","DDX3X,DDX3Y,DDX1,DDX4","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-642","NOP56","snoRNA","snoRNA"]
["family-643","RPS20","ribosome","ribosome"]
["family-644","MPHOSPH10","snoRNA","snoRNA"]
["family-645","MRM1","rRNA","rRNA"]
["family-646","DXO","diverse","diverse"]
["family-647","DENR","mRNA","mRNA"]
["family-648","RPL21","ribosome","ribosome"]
["family-649","RPS10","ribosome","ribosome"]
["family-65","NAT10","rRNA","rRNA"]
["family-650","UTP18","snoRNA","snoRNA"]
["family-651","NOL12","rRNA","rRNA"]
["family-652","DDX31","rRNA","rRNA"]
["family-653","ABCF1,ABCF3","mRNA,NA","mRNA"]
["family-654","DNMT1","ncRNA","ncRNA"]
["family-655","SNRPA1","snRNA","snRNA"]
["family-656","API5","mRNA","mRNA"]
["family-657","SHQ1","snoRNA","snoRNA"]
["family-658","AKAP1","mRNA","mRNA"]
["family-659","FTO","mRNA","mRNA"]
["family-66","PUF60","mRNA","mRNA"]
["family-660","SAMHD1","diverse","diverse"]
["family-661","RBM45","mRNA","mRNA"]
["family-662","FAM98A,FAM98B,FAM98C","mRNA,tRNA,unknown","tRNA"]
["family-663","PCF11","mRNA","mRNA"]
["family-664","EIF5","mRNA","mRNA"]
["family-665","ZC3HC1","unknown","unknown"]
["family-666","HNRNPC,HNRNPCL1,RALY,RALYL","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-667","SEPSECS","tRNA","tRNA"]
["family-668","NPM1,NPM3,NPM2","rRNA,rRNA,rRNA","rRNA"]
["family-669","NUPL2","mRNA","mRNA"]
["family-67","MRPS14","ribosome","ribosome"]
["family-670","SF3A1","snRNA","snRNA"]
["family-671","EIF3A","mRNA","mRNA"]
["family-672","FASTKD5","mRNA","mRNA"]
["family-673","TDRD3","mRNA","mRNA"]
["family-674","SNRPB,SNRPN","snRNA,snRNA","snRNA"]
["family-675","YRDC","tRNA","tRNA"]
["family-676","POLR2K","mRNA","mRNA"]
["family-677","ERN1,ERN2","mRNA,mRNA","mRNA"]
["family-678","RPL5","ribosome","ribosome"]
["family-679","RPS17,RPS17L","ribosome,ribosome","ribosome"]
["family-68","DARS","tRNA","tRNA"]
["family-680","IPO7,IPO8","mRNA,ncRNA","mRNA"]
["family-681","SMN1,SMN2","snRNA,snRNA","snRNA"]
["family-682","GTPBP4","rRNA","rRNA"]
["family-683","MRPL13","ribosome","ribosome"]
["family-684","MRPL46","ribosome","ribosome"]
["family-685","LSM5","snRNA","snRNA"]
["family-686","EIF4G1,EIF4G3,EIF4G2","mRNA,mRNA,mRNA","mRNA"]
["family-687","GTF2F1","mRNA","mRNA"]
["family-688","RPS15A","ribosome","ribosome"]
["family-689","PIH1D2","unknown","unknown"]
["family-69","TTF2","mRNA","mRNA"]
["family-690","PUS3","tRNA","tRNA"]
["family-691","RBM11,RBM7","mRNA,mRNA","mRNA"]
["family-692","TSEN2","tRNA","tRNA"]
["family-693","RBM42","mRNA","mRNA"]
["family-694","UTP3","snoRNA","snoRNA"]
["family-695","HNRNPL,HNRNPLL,PTBP3,PTBP2,PTBP1","mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-696","SYMPK","mRNA","mRNA"]
["family-697","POLR2F","mRNA","mRNA"]
["family-698","TSR2","rRNA","rRNA"]
["family-699","KIAA0391","ncRNA","ncRNA"]
["family-7","POLR2G","mRNA","mRNA"]
["family-70","ATG16L1,WDR38,DAW1,WDR5,WDR5B,ATG16L2,SNRNP40,WDR83","NA,NA,NA,ncRNA,NA,NA,snRNA,mRNA","mRNA"]
["family-700","ZFC3H1","unknown","unknown"]
["family-701","RPL15","ribosome","ribosome"]
["family-702","SNRNP35,SNRNP70","snRNA,snRNA","snRNA"]
["family-703","MRPL39","ribosome","ribosome"]
["family-704","TLR3,TLR4,TLR5,TLR7,TLR8,TLR9,CD180","ncRNA,NA,NA,ncRNA,ncRNA,NA,NA","ncRNA"]
["family-705","NAA38","snoRNA","snoRNA"]
["family-706","PRPF31","snRNA","snRNA"]
["family-707","MRPL55","ribosome","ribosome"]
["family-708","TRMT2A,TRMT2B","tRNA,tRNA","tRNA"]
["family-709","RPS3A","ribosome","ribosome"]
["family-71","BRCA1","ncRNA","ncRNA"]
["family-710","RIOK2","rRNA","rRNA"]
["family-711","DHX15,DHX33,DHX8,DHX35,DHX32,DHX16,DQX1","mRNA,mRNA,mRNA,mRNA,mRNA,snRNA,mRNA","mRNA"]
["family-712","MRPS5","ribosome","ribosome"]
["family-713","SAP18","mRNA","mRNA"]
["family-714","EEFSEC,TUFM","tRNA,mRNA","tRNA"]
["family-715","TDRD12","ncRNA","ncRNA"]
["family-716","SKIV2L2","diverse","diverse"]
["family-717","TRDMT1","tRNA","tRNA"]
["family-718","ZFP62,ZNF814,ZNF629,ZNF347,ZNF836,ZNF473,ZNF268,ZNF845,ZNF585A,ZNF160,ZNF658,ZNF197,ZNF841,ZNF616,ZNF585B,ZNF808,ZNF107,ZNF99,ZNF43,ZNF721,ZNF493,ZNF780B,ZNF546,ZNF624,ZNF594","NA,NA,NA,NA,NA,snRNA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA","snRNA"]
["family-719","FCF1","rRNA","rRNA"]
["family-72","URB1","rRNA","rRNA"]
["family-720","CARS,CARS2","tRNA,tRNA","tRNA"]
["family-721","CELF1,CELF2,CELF4,CELF5,CELF6,CELF3,CELF6","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-722","XPO1","mRNA","mRNA"]
["family-723","DDX17,DDX5,DDX42,DDX46,DDX53,DDX43","mRNA,mRNA,mRNA,snRNA,mRNA,mRNA","mRNA"]
["family-724","FIP1L1","mRNA","mRNA"]
["family-725","MRPL14","ribosome","ribosome"]
["family-726","TXNL4A,TXNL4B","snRNA,snRNA","snRNA"]
["family-727","RBM23,RBM39","mRNA,mRNA","mRNA"]
["family-728","CPEB1,CPEB2,CPEB4,CPEB3","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-729","INTS9","snRNA","snRNA"]
["family-73","CACTIN","mRNA","mRNA"]
["family-730","MPHOSPH6","rRNA","rRNA"]
["family-731","RPL34","ribosome","ribosome"]
["family-732","OBFC1","unknown","unknown"]
["family-733","RPS12","ribosome","ribosome"]
["family-734","PRPF8","snRNA","snRNA"]
["family-735","SECISBP2,SECISBP2L","mRNA,mRNA","mRNA"]
["family-736","RPUSD3,RPUSD4","mRNA,mRNA","mRNA"]
["family-737","DDX6","mRNA","mRNA"]
["family-738","RPL28","ribosome","ribosome"]
["family-739","ELAC1","tRNA","tRNA"]
["family-74","NOM1","rRNA","rRNA"]
["family-740","TROVE2","ncRNA","ncRNA"]
["family-741","EEF1E1","tRNA","tRNA"]
["family-742","TARS,TARS2,TARSL2","tRNA,tRNA,tRNA","tRNA"]
["family-743","IARS","tRNA","tRNA"]
["family-744","RPL18A","ribosome","ribosome"]
["family-745","ESF1","rRNA","rRNA"]
["family-746","EEF2,EFTUD2","tRNA,tRNA","tRNA"]
["family-747","DDX60,DDX60L","ncRNA,ncRNA","ncRNA"]
["family-748","MRPL2","ribosome","ribosome"]
["family-749","SLC4A1AP","unknown","unknown"]
["family-75","MAZ,PATZ1,VEZF1","unknown,NA,NA","unknown"]
["family-750","EIF2S3,EIF2S3L","tRNA,tRNA","tRNA"]
["family-751","AIMP1","tRNA","tRNA"]
["family-752","APEX1,APEX2","mRNA,NA","mRNA"]
["family-753","EIF3J","mRNA","mRNA"]
["family-754","PABPC1,PABPC1L,PABPC3,PABPC4L,PABPC4,PABPC5,PABPC1L2A,PABPC1L2B","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-755","MEX3A,MEX3D,MEX3B,MEX3C","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-756","GEMIN7","snRNA","snRNA"]
["family-757","MRPS23","ribosome","ribosome"]
["family-758","HDGF,HDGFL1,HDGFRP3,HDGFRP2,PSIP1","NA,NA,NA,NA,mRNA","mRNA"]
["family-759","SRP54","ncRNA","ncRNA"]
["family-76","FARSB","tRNA","tRNA"]
["family-760","RBM15,RBM15B,SPEN","mRNA,mRNA,mRNA","mRNA"]
["family-761","DNAAF2","unknown","unknown"]
["family-762","SF3B1","mRNA","mRNA"]
["family-763","RNASEH2B","diverse","diverse"]
["family-764","FARSA","tRNA","tRNA"]
["family-765","NOB1","rRNA","rRNA"]
["family-766","EIF2A","tRNA","tRNA"]
["family-767","RNASEL","ncRNA","ncRNA"]
["family-768","TRNT1","tRNA","tRNA"]
["family-769","EIF4ENIF1","mRNA","mRNA"]
["family-77","MECP2","mRNA","mRNA"]
["family-770","RBM22","mRNA","mRNA"]
["family-771","CMTR1","mRNA","mRNA"]
["family-772","RPL39,RPL39L","ribosome,ribosome","ribosome"]
["family-773","RPSA,RPSAP58","ribosome,NA","ribosome"]
["family-774","PARP4,VWA5A","ncRNA,NA","ncRNA"]
["family-775","CSTF1,SPAG16","mRNA,NA","mRNA"]
["family-776","NCBP1","mRNA","mRNA"]
["family-777","SNRNP25","snRNA","snRNA"]
["family-778","DNAJC21","unknown","unknown"]
["family-779","CWC22","mRNA","mRNA"]
["family-78","NFX1,NFXL1","mRNA,NA","mRNA"]
["family-780","MRPS31","ribosome","ribosome"]
["family-781","SMG5","mRNA","mRNA"]
["family-782","SART1","snRNA","snRNA"]
["family-783","GEMIN2","snRNA","snRNA"]
["family-784","NR0B1,NR0B2","mRNA,NA","mRNA"]
["family-785","DCP2","mRNA","mRNA"]
["family-786","EWSR1,TAF15,FUS","mRNA,mRNA,mRNA","mRNA"]
["family-787","EDC4","mRNA","mRNA"]
["family-788","FBL,FBLL1","snoRNA,snoRNA","snoRNA"]
["family-789","MRPS27","ribosome","ribosome"]
["family-79","ALKBH1","mRNA","mRNA"]
["family-790","ZCCHC17","unknown","unknown"]
["family-791","MRPL49","ribosome","ribosome"]
["family-792","RPL18","ribosome","ribosome"]
["family-793","RPS4X,RPS4Y2,RPS4Y1","ribosome,ribosome,ribosome","ribosome"]
["family-794","NOP14","rRNA","rRNA"]
["family-795","KRR1","snoRNA","snoRNA"]
["family-796","NCL","snoRNA","snoRNA"]
["family-797","PRPF18","mRNA","mRNA"]
["family-798","C1D","rRNA","rRNA"]
["family-799","ADAT3","tRNA","tRNA"]
["family-8","UTP20","snoRNA","snoRNA"]
["family-80","SNIP1","ncRNA","ncRNA"]
["family-800","GUF1","mRNA","mRNA"]
["family-801","GCFC2,PAXBP1","mRNA,NA","mRNA"]
["family-802","UTP6","snoRNA","snoRNA"]
["family-803","SRSF1,SRSF7,SRSF3,SRSF9,SRSF4,SRSF5,SRSF6","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-804","USB1","snRNA","snRNA"]
["family-805","NOL6","rRNA","rRNA"]
["family-806","PPIA,PPIF,PPIE,PPIAL4A,PPIAL4D,PPIAL4B,PPIAL4C,PPIAL4G","NA,NA,mRNA,NA,NA,NA,NA,NA","mRNA"]
["family-807","KTN1,RRBP1","NA,mRNA","mRNA"]
["family-808","SUZ12","ncRNA","ncRNA"]
["family-809","TERT","ncRNA","ncRNA"]
["family-81","MSL3","ncRNA","ncRNA"]
["family-810","BICC1","mRNA","mRNA"]
["family-811","MRPS16","ribosome","ribosome"]
["family-812","RBMX2","mRNA","mRNA"]
["family-813","MRPL40","ribosome","ribosome"]
["family-814","AEN,ISG20L2,ISG20,REXO4","diverse,rRNA,ncRNA,rRNA","rRNA"]
["family-815","TGS1","snRNA","snRNA"]
["family-816","ZC3H4,ZC3H6,ZC3H8","unknown,unknown,unknown","unknown"]
["family-817","RPL27A","ribosome","ribosome"]
["family-818","RPS19","ribosome","ribosome"]
["family-819","SYF2","mRNA","mRNA"]
["family-82","DIMT1,TFB1M","rRNA,rRNA","rRNA"]
["family-820","TSEN34","tRNA","tRNA"]
["family-821","DCAF13","rRNA","rRNA"]
["family-822","RPL9","ribosome","ribosome"]
["family-823","AKAP13,ARHGEF2,ARHGEF18,ARHGEF28","NA,NA,NA,mRNA","mRNA"]
["family-824","AC004381.6","rRNA","rRNA"]
["family-825","EIF4B,EIF4H","mRNA,mRNA","mRNA"]
["family-826","DDX54","rRNA","rRNA"]
["family-827","MRPS36","ribosome","ribosome"]
["family-828","PRPF40A,PRPF40B","snRNA,snRNA","snRNA"]
["family-829","EIF3L","mRNA","mRNA"]
["family-83","NOL8","rRNA","rRNA"]
["family-830","MTO1","tRNA","tRNA"]
["family-831","PSMA1,PSMA1,PSMA1","unknown,unknown,unknown","unknown"]
["family-832","HTATSF1","mRNA","mRNA"]
["family-833","FTSJ1","tRNA","tRNA"]
["family-834","LAS1L","rRNA","rRNA"]
["family-835","POP1","ncRNA","ncRNA"]
["family-836","DZIP3","mRNA","mRNA"]
["family-837","DGCR14","mRNA","mRNA"]
["family-838","CDK10,CDK11B,CDK11A,CDK13,CDK9,CDK12","NA,NA,NA,NA,ncRNA,NA","ncRNA"]
["family-839","PAN3","mRNA","mRNA"]
["family-84","RPL29","ribosome","ribosome"]
["family-840","DCPS","mRNA","mRNA"]
["family-841","MRP63","ribosome","ribosome"]
["family-842","MRPL27","ribosome","ribosome"]
["family-843","POLR2H","mRNA","mRNA"]
["family-844","ZNF239,ZNF664","unknown,NA","unknown"]
["family-845","XRN1","diverse","diverse"]
["family-846","ZFR,ZFR2","unknown,unknown","unknown"]
["family-847","AGFG1,AGFG2","mRNA,NA","mRNA"]
["family-848","NSA2","rRNA","rRNA"]
["family-849","DDX10","rRNA","rRNA"]
["family-85","TBL3","snoRNA","snoRNA"]
["family-850","INTS2","snRNA","snRNA"]
["family-851","YBX1,YBX3,YBX2","mRNA,mRNA,mRNA","mRNA"]
["family-852","SURF6","rRNA","rRNA"]
["family-853","THOC6","mRNA","mRNA"]
["family-854","EIF3I,STRAP","mRNA,mRNA","mRNA"]
["family-855","RPL13","ribosome","ribosome"]
["family-856","RRP12","rRNA","rRNA"]
["family-857","MRPS2","ribosome","ribosome"]
["family-858","ZCCHC8","mRNA","mRNA"]
["family-859","EFTUD1","tRNA","tRNA"]
["family-86","RPL35","ribosome","ribosome"]
["family-860","NSRP1","mRNA","mRNA"]
["family-861","RPUSD2","tRNA","tRNA"]
["family-862","BCDIN3D","ncRNA","ncRNA"]
["family-863","THUMPD1","tRNA","tRNA"]
["family-864","TRIM21,TRIML1,TRIM27,TRIM17,TRIM4,TRIM68,TRIM11,TRIM39,TRIM7,TRIM60,TRIM34,TRIM6,TRIM22,TRIM5,TRIM38,TRIM58","ncRNA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA,NA","ncRNA"]
["family-865","RANBP17,XPO7","mRNA,mRNA","mRNA"]
["family-866","TRMT12","tRNA","tRNA"]
["family-867","ACIN1","mRNA","mRNA"]
["family-868","ZNF385A,ZNF385B,ZNF385D,ZNF385C","mRNA,NA,NA,NA","mRNA"]
["family-869","RPL23","ribosome","ribosome"]
["family-87","EED","ncRNA","ncRNA"]
["family-870","DNTTIP2","rRNA","rRNA"]
["family-871","SBDS","rRNA","rRNA"]
["family-872","DDX51","rRNA","rRNA"]
["family-873","RBM18","mRNA","mRNA"]
["family-874","IPO11","mRNA","mRNA"]
["family-875","RPL22,RPL22L1","ribosome,ribosome","ribosome"]
["family-876","LCMT1,LCMT2","NA,tRNA","tRNA"]
["family-877","ZC3H11A","unknown","unknown"]
["family-878","FYTTD1","mRNA","mRNA"]
["family-879","RNPS1","mRNA","mRNA"]
["family-88","RPS23","ribosome","ribosome"]
["family-880","RNASEH2A","diverse","diverse"]
["family-881","FRG1,FRG1B","mRNA,mRNA","mRNA"]
["family-882","NOL7","unknown","unknown"]
["family-883","PRPF38A","snRNA","snRNA"]
["family-884","RBM41","mRNA","mRNA"]
["family-885","HNRNPF,RBM12,ESRP1,RBM12B,ESRP2,HNRNPH1,HNRNPH2,HNRNPH3,GRSF1","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-886","RNH1","diverse","diverse"]
["family-887","NOL9","rRNA","rRNA"]
["family-888","SRFBP1","rRNA","rRNA"]
["family-889","ARL6IP4","mRNA","mRNA"]
["family-89","RPP40","ncRNA","ncRNA"]
["family-890","ALKBH5","mRNA","mRNA"]
["family-891","SMG7","mRNA","mRNA"]
["family-892","ANGEL1,ANGEL2,CCRN4L,CNOT6,CNOT6L,PDE12","mRNA,mRNA,mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-893","PDCD11","snoRNA","snoRNA"]
["family-894","RPL35A","ribosome","ribosome"]
["family-895","MRPL21","ribosome","ribosome"]
["family-896","SMG6","mRNA","mRNA"]
["family-897","PRPF19,PRPF4","mRNA,snRNA","mRNA"]
["family-898","INTS4","snRNA","snRNA"]
["family-899","SRPK1,SRPK2,SRPK3","NA,mRNA,NA","mRNA"]
["family-9","SUPV3L1","mRNA","mRNA"]
["family-90","RBM17","mRNA","mRNA"]
["family-900","NAF1","snoRNA","snoRNA"]
["family-901","YARS","tRNA","tRNA"]
["family-902","LRRFIP1,LRRFIP2","ncRNA,ncRNA","ncRNA"]
["family-903","EIF4E,EIF4E1B,EIF4E3,EIF4E2","mRNA,mRNA,mRNA,mRNA","mRNA"]
["family-904","BUD13","mRNA","mRNA"]
["family-905","CTU1","tRNA","tRNA"]
["family-906","GTPBP1,GTPBP2","mRNA,mRNA","mRNA"]
["family-907","MTERFD2","rRNA","rRNA"]
["family-908","SRPR","ncRNA","ncRNA"]
["family-909","DDX21,DDX50","rRNA,rRNA","rRNA"]
["family-91","ZCRB1","snRNA","snRNA"]
["family-910","RPL13A","ribosome","ribosome"]
["family-911","SRA1","ncRNA","ncRNA"]
["family-912","PAPOLA,PAPOLB,PAPOLG","mRNA,mRNA,mRNA","mRNA"]
["family-913","RPL41","ribosome","ribosome"]
["family-914","ZNF768","unknown","unknown"]
["family-915","SCAF1","mRNA","mRNA"]
["family-916","MRPS15","ribosome","ribosome"]
["family-917","RNASET2","diverse","diverse"]
["family-918","EIF2B1","mRNA","mRNA"]
["family-919","RPL36A,RPL36AL","ribosome,ribosome","ribosome"]
["family-92","DDX26B,INTS6","mRNA,snRNA","mRNA"]
["family-920","RPS7","ribosome","ribosome"]
["family-921","METTL25,RRNAD1","NA,unknown","unknown"]
["family-922","MRPS21","ribosome","ribosome"]
["family-923","SETD7","ncRNA","ncRNA"]
["family-924","RBM8A","mRNA","mRNA"]
["family-925","MAGOH,MAGOHB","mRNA,mRNA","mRNA"]
["family-926","RPL37A","ribosome","ribosome"]
["family-927","NOLC1","snoRNA","snoRNA"]
["family-928","IARS2","tRNA","tRNA"]
["family-929","LSM1","snRNA","snRNA"]
["family-93","SUPT4H1","mRNA","mRNA"]
["family-930","EXO1","diverse","diverse"]
["family-931","DCP1A,DCP1B","mRNA,mRNA","mRNA"]
["family-932","DNAJC12,DNAJC17","NA,unknown","unknown"]
["family-933","DUSP11,RNGTT","mRNA,mRNA","mRNA"]
["family-934","CHERP","mRNA","mRNA"]
["family-935","AAMP,WDR61","NA,mRNA","mRNA"]
["family-936","NANOS1,NANOS2,NANOS3","mRNA,mRNA,mRNA","mRNA"]
["family-937","EBNA1BP2","rRNA","rRNA"]
["family-938","HELZ","mRNA","mRNA"]
["family-939","RNMTL1","rRNA","rRNA"]
["family-94","PDCD4","mRNA","mRNA"]
["family-940","PTRH2","tRNA","tRNA"]
["family-941","SART3","snRNA","snRNA"]
["family-942","ZC3H10","unknown","unknown"]
["family-943","LSM2","snRNA","snRNA"]
["family-944","MRPS25","ribosome","ribosome"]
["family-945","RPP21","ncRNA","ncRNA"]
["family-946","ZMAT2","snRNA","snRNA"]
["family-947","IFIT1,IFIT1B,IFIT5,IFIT3,IFIT2","ncRNA,ncRNA,tRNA,ncRNA,ncRNA","ncRNA"]
["family-948","NOVA1,NOVA2","mRNA,mRNA","mRNA"]
["family-949","SNRPD3","snRNA","snRNA"]
["family-95","YARS2","tRNA","tRNA"]
["family-950","PTCD1","tRNA","tRNA"]
["family-951","TSR1","rRNA","rRNA"]
["family-952","MRPS6","ribosome","ribosome"]
["family-953","TAF9,TAF9B","snoRNA,NA","snoRNA"]
["family-954","RPL11","ribosome","ribosome"]
["family-955","DDX23,DDX59","snRNA,mRNA","mRNA"]
["family-956","CCNC,CCNT1,CCNT2,CCNK,CCNL1,CCNL2,FAM58A","NA,ncRNA,ncRNA,NA,NA,NA,NA","ncRNA"]
["family-957","RPL8","ribosome","ribosome"]
["family-958","SARNP","mRNA","mRNA"]
["family-959","IMP3","snoRNA","snoRNA"]
["family-96","SRRM4","mRNA","mRNA"]
["family-960","CNP","mRNA","mRNA"]
["family-961","LIN28A,LIN28B","mRNA,mRNA","mRNA"]
["family-962","EIF3K","mRNA","mRNA"]
["family-963","SF3B14","mRNA","mRNA"]
["family-964","EIF2S2","tRNA","tRNA"]
["family-965","RNMT","mRNA","mRNA"]
["family-966","MRPL42","ribosome","ribosome"]
["family-967","BCLAF1,THRAP3,CXorf23","mRNA,mRNA,mRNA","mRNA"]
["family-968","PNO1","rRNA","rRNA"]
["family-969","RBM14,RBM14-RBM4,RBM4,RBM4B","mRNA,NA,mRNA,mRNA","mRNA"]
["family-97","R3HCC1,R3HCC1L","unknown,unknown","unknown"]
["family-970","KIAA0430","ncRNA","ncRNA"]
["family-971","POP5","ncRNA","ncRNA"]
["family-972","MRPL51","ribosome","ribosome"]
["family-973","MARS","tRNA","tRNA"]
["family-974","TYW1,TYW1B","tRNA,NA","tRNA"]
["family-975","MRPL16","ribosome","ribosome"]
["family-976","DUS1L","tRNA","tRNA"]
["family-977","QRSL1","tRNA","tRNA"]
["family-978","WARS2","tRNA","tRNA"]
["family-979","WRAP53","ncRNA","ncRNA"]
["family-98","RSL24D1","rRNA","rRNA"]
["family-980","SF3B4","mRNA","mRNA"]
["family-981","TDRD7","mRNA","mRNA"]
["family-982","LARP1,LARP1B","mRNA,mRNA","mRNA"]
["family-983","RPL23A","ribosome","ribosome"]
["family-984","BAZ2A,BAZ2B","ncRNA,ncRNA","ncRNA"]
["family-985","EIF3E","mRNA","mRNA"]
["family-986","CWC15","mRNA","mRNA"]
["family-987","TOP1,TOP1MT","unknown,NA","unknown"]
["family-988","RPL31","ribosome","ribosome"]
["family-989","SUPT6H","mRNA","mRNA"]
["family-99","MPST,TST","NA,rRNA","rRNA"]
["family-990","HNRNPU,HNRNPUL2,HNRNPUL1","mRNA,mRNA,mRNA","mRNA"]
["family-991","RPS25","ribosome","ribosome"]
["family-992","MRPL23","ribosome","ribosome"]
["family-993","EIF1AD","mRNA","mRNA"]
["family-994","SETX","mRNA","mRNA"]
["family-995","MARS2","tRNA","tRNA"]
["family-996","CNOT3","mRNA","mRNA"]
["family-997","MTIF2","tRNA","tRNA"]
["family-998","JAKMIP1,JAKMIP2,JAKMIP3","mRNA,NA,NA","mRNA"]
["family-999","FASTKD1","mRNA","mRNA"]