{"text_format":"3","workbook":"xlsx","n_sheets":2,"sheets":["SMPDB","Predicted metabolite sets"],"read":"whole","date_system":"1900"}

{"sheet":"SMPDB","index":0,"n_rows":39,"n_cols":8,"rows_kept":39}
[null,"Total","Expected","Hits","Raw P","Holm P","FDR","Enriched_Compounds"]
["Alpha Linolenic Acid and Linoleic Acid Metabolism",19,0.779,5,0.000693,0.0679,0.0679,"Linoleic acid\nAlpha-Linolenic acid\nDocosahexaenoic acid\nAdrenic acid\n8,11,14-Eicosatrienoic acid"]
["Beta Oxidation of Very Long Chain Fatty Acids",17,0.697,3,0.0292,1,1,"L-Carnitine\nL-Acetylcarnitine\nCaprylic acid"]
["Valine, Leucine and Isoleucine Degradation",60,2.46,6,0.0314,1,1,"Alpha-ketoisovaleric acid\nL-Isoleucine\n3-Methyl-2-oxovaleric acid\nL-Leucine\nKetoleucine\nL-Valine"]
["Fatty Acid Biosynthesis",35,1.44,4,0.0508,1,1,"Acetic acid\nPalmitic acid\nCaprylic acid\nMyristic acid"]
["Bile Acid Biosynthesis",65,2.67,5,0.121,1,1,"Taurocholic acid\nGlycocholic acid\nPalmitic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["Aspartate Metabolism",35,1.44,3,0.17,1,1,"Acetic acid\nL-Arginine\nN-Acetyl-L-aspartic acid"]
["Carnitine Synthesis",22,0.902,2,0.227,1,1,"L-Carnitine\nL-Lysine"]
["Transfer of Acetyl Groups into Mitochondria",22,0.902,2,0.227,1,1,"Citric acid\nD-Glucose"]
["Glycerolipid Metabolism",25,1.03,2,0.274,1,1,"Glyceric acid\nPalmitic acid"]
["Biotin Metabolism",8,0.328,1,0.286,1,1,"L-Lysine"]
["Oxidation of Branched Chain Fatty Acids",26,1.07,2,0.289,1,1,"L-Carnitine\nL-Acetylcarnitine"]
["Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids",27,1.11,2,0.305,1,1,"L-Carnitine\nCaprylic acid"]
["Lactose Degradation",9,0.369,1,0.315,1,1,"D-Glucose"]
["Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids",28,1.15,2,0.32,1,1,"L-Carnitine\nStearic acid"]
["Citric Acid Cycle",32,1.31,2,0.381,1,1,"Citric acid\nIsocitric acid"]
["Amino Sugar Metabolism",33,1.35,2,0.396,1,1,"Acetic acid\nD-Fructose"]
["Ketone Body Metabolism",13,0.533,1,0.422,1,1,"(R)-3-Hydroxybutyric acid"]
["Glucose-Alanine Cycle",13,0.533,1,0.422,1,1,"D-Glucose"]
["Warburg Effect",58,2.38,3,0.429,1,1,"Citric acid\nD-Glucose\nIsocitric acid"]
["Glycine and Serine Metabolism",59,2.42,3,0.441,1,1,"Creatine\nGlyceric acid\nL-Arginine"]
["Galactose Metabolism",38,1.56,2,0.469,1,1,"D-Glucose\nD-Fructose"]
["Fatty acid Metabolism",43,1.76,2,0.536,1,1,"L-Carnitine\nPalmitic acid"]
["Ethanol Degradation",19,0.779,1,0.552,1,1,"Acetic acid"]
["Lactose Synthesis",20,0.82,1,0.571,1,1,"D-Glucose"]
["Arginine and Proline Metabolism",53,2.17,2,0.653,1,1,"Creatine\nL-Arginine"]
["Glycolysis",25,1.03,1,0.653,1,1,"D-Glucose"]
["Plasmalogen Synthesis",26,1.07,1,0.668,1,1,"Stearic acid"]
["Pentose Phosphate Pathway",29,1.19,1,0.708,1,1,"Gluconolactone"]
["Urea Cycle",29,1.19,1,0.708,1,1,"L-Arginine"]
["Lysine Degradation",30,1.23,1,0.721,1,1,"L-Lysine"]
["Starch and Sucrose Metabolism",31,1.27,1,0.732,1,1,"D-Fructose"]
["Fructose and Mannose Degradation",32,1.31,1,0.744,1,1,"D-Fructose"]
["Fatty Acid Elongation In Mitochondria",35,1.44,1,0.775,1,1,"Palmitic acid"]
["Gluconeogenesis",35,1.44,1,0.775,1,1,"D-Glucose"]
["Sphingolipid Metabolism",40,1.64,1,0.819,1,1,"D-Glucose"]
["Propanoate Metabolism",42,1.72,1,0.834,1,1,"L-Valine"]
["Steroid Biosynthesis",48,1.97,1,0.872,1,1,"Palmitic acid"]
["Pyruvate Metabolism",48,1.97,1,0.872,1,1,"Acetic acid"]

{"sheet":"Predicted metabolite sets","index":1,"n_rows":198,"n_cols":8,"rows_kept":198}
[null,"Total","Expected","Hits","Raw P","Holm P","FDR","Enriched_Compounds"]
["methylmalonyl-CoA mutase",8,1.45,5,0.00573,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nL-Isoleucine"]
["Propionyl-CoA carboxylase, mitochondrial",8,1.45,5,0.00573,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nL-Isoleucine"]
["L-carnitine transport out of mitochondria via diffusion",7,1.27,4,0.0217,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid"]
["fatty acyl-CoA desaturase (n-C18:2CoA -> n-C18:3CoA)",5,0.905,3,0.0426,1,1,"8,11,14-Eicosatrienoic acid\nLinoleic acid\nAlpha-Linolenic acid"]
["pyridoxal kinase",17,3.08,6,0.0636,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["cysteinesulfinic acid oxidase",17,3.08,6,0.0636,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Hypotaurine oxidase",17,3.08,6,0.0636,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Reduced glutathione exchange",18,3.26,6,0.0825,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["L-Ascorbate exchange",18,3.26,6,0.0825,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Linoleic acid (n-C18:2) transport in via diffusion",3,0.543,2,0.0852,1,1,"8,11,14-Eicosatrienoic acid\nLinoleic acid"]
["carnitine O-palmitoyltransferase",3,0.543,2,0.0852,1,1,"Linoleic acid\nAlpha-Linolenic acid"]
["Beta oxidation of fatty acid",3,0.543,2,0.0852,1,1,"Linoleic acid\nAlpha-Linolenic acid"]
["pyridoxal transport via diffusion",19,3.44,6,0.104,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Arachidic acid exchange",19,3.44,6,0.104,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Nitric Oxide Synthase (NO forming)",28,5.07,8,0.105,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["2-aminomuconate reductase",20,3.62,6,0.129,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["aminomuconate-semialdehyde dehydrogenase",20,3.62,6,0.129,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["picolinic acid decarboxylase",20,3.62,6,0.129,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Glutathione:cystine oxidoreductase",20,3.62,6,0.129,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["transport into the mitochondria (carnitine)",4,0.724,2,0.151,1,1,"Alpha-Linolenic acid\nLinoleic acid"]
["carnitine transferase",4,0.724,2,0.151,1,1,"Linoleic acid\nAlpha-Linolenic acid"]
["Vitamin D3 uptake",12,2.17,4,0.152,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid"]
["ATP transporter, peroxisomal",12,2.17,4,0.152,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid"]
["3-Hydroxy-L-kynurenine hydrolase",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["3-hydroxyanthranilate 3,4-dioxygenase",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["5-hydroxy-L-tryptophan secretion via secretory vesicle (ATP driven)",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["kynurenine 3-monooxygenase",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing)",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["N-Formyl-L-kynurenine amidohydrolase",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["nicotinate-nucleotide diphosphorylase (carboxylating)",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["Quinolinate Synthase (Eukaryotic)",21,3.8,6,0.156,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["O2 transport, endoplasmic reticulum",13,2.35,4,0.192,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid"]
["dehydroascorbate transport (uniport)",27,4.89,7,0.192,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nAdrenic acid\nOxalic acid"]
["H2O transport, lysosomal",5,0.905,2,0.223,1,1,"D-Fructose\nD-Glucose"]
["N-acetylglucosamine-6-phosphate deacetylase",5,0.905,2,0.223,1,1,"D-Fructose\nD-Glucose"]
["Glutathione dehydrogenase (dehydroascorbate reductase)",29,5.25,7,0.252,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nAdrenic acid\nOxalic acid"]
["hydrogen peroxide transport via diffusion",35,6.34,8,0.281,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["o2 transport (diffusion)",35,6.34,8,0.281,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Iodide:hydrogen-peroxide oxidoreductase 4",25,4.53,6,0.285,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["L-Thyroxine exchange",25,4.53,6,0.285,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nOxalic acid"]
["glucosamine-6-phosphate deaminase",6,1.09,2,0.298,1,1,"D-Fructose\nD-Glucose"]
["2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["3-amino-isobutyrate transport",2,0.362,1,0.33,1,1,"L-Valine"]
["3-amino-isobutyrate transport, mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["3-hydroxyacyl-CoA dehydratase (3-hydroxyisobutyryl-CoA) (mitochondria)",2,0.362,1,0.33,1,1,"L-Valine"]
["3-hydroxyisobutyrate dehydrogenase, mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["3-hydroxyisobutyryl-CoA hydrolase, mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["acyl-CoA dehydrogenase (isobutyryl-CoA), mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["L-3-Amino-isobutanoate exchange",2,0.362,1,0.33,1,1,"L-Valine"]
["L-3-aminoisobutyrate transaminase, mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["malonate-semialdehyde dehydrogenase (acetylating), mitochondrial",2,0.362,1,0.33,1,1,"L-Valine"]
["methylmalonate-semialdehyde dehydrogenase",2,0.362,1,0.33,1,1,"L-Valine"]
["Fatty acid omega-hydroxylase",2,0.362,1,0.33,1,1,"Myristic acid"]
["dihomo-gamma-linolenic acid (n-6) exchange",2,0.362,1,0.33,1,1,"8,11,14-Eicosatrienoic acid"]
["L-Lysine exchange",2,0.362,1,0.33,1,1,"L-Lysine"]
["H+ exchange",2,0.362,1,0.33,1,1,"Citric acid"]
["fatty-acyl-CoA elongation (n-C20:5CoA)",2,0.362,1,0.33,1,1,"Docosahexaenoic acid"]
["gamma-linolenic acid exchange",2,0.362,1,0.33,1,1,"Linoleic acid"]
["fatty-acid--CoA ligase (tetradecanoate)",2,0.362,1,0.33,1,1,"Myristic acid"]
["omega hydroxy tetradecanoate (n-C14:0) exchange",2,0.362,1,0.33,1,1,"Myristic acid"]
["Tetradecanoate (n-C14:0) transport in via uniport",2,0.362,1,0.33,1,1,"Myristic acid"]
["carbamoyl-phosphate synthase (ammonia) (mitochondria",2,0.362,1,0.33,1,1,"Creatine"]
["Creatine transport (sodium symport) (2:1)",2,0.362,1,0.33,1,1,"Creatine"]
["ornithine carbamoyltransferase, irreversible",2,0.362,1,0.33,1,1,"Creatine"]
["Urea exchange",2,0.362,1,0.33,1,1,"Creatine"]
["fatty acid transport via diffusion",22,3.98,5,0.364,1,1,"Alpha-Linolenic acid\n8,11,14-Eicosatrienoic acid\nAdrenic acid\nDocosahexaenoic acid\nPalmitoleic acid"]
["alpha-mannosidase, lysosomal",7,1.27,2,0.371,1,1,"D-Fructose\nD-Glucose"]
["beta-mannosidase, lysosomal",7,1.27,2,0.371,1,1,"D-Fructose\nD-Glucose"]
["DM Asn-X-Ser/Thr(ly)",7,1.27,2,0.371,1,1,"D-Fructose\nD-Glucose"]
["mannose efflux from lysosome",7,1.27,2,0.371,1,1,"D-Fructose\nD-Glucose"]
["dimethylallyltranstransferase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["geranyltranstransferase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["isopentenyl-diphosphate D-isomerase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Carbon monoxide exchange",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["CO transporter via diffusion",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["coproporphyrinogen oxidase (O2 required)",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Ferrochelatase, mitochondrial",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Heme oxygenase 1",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Heme transport to cytosol",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["hydroxymethylbilane synthase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["iron (II) transport",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Nad(p)h biliverdin reductase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["protoporphyrinogen IX mitochondrial transport",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["uroporphyrinogen decarboxylase (uroporphyrinogen III)",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["uroporphyrinogen-III synthase",39,7.06,8,0.409,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["7-alpha,24(S)-Dihydroxycholesterol exchange",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["7-alpha,25-Dihydroxycholesterol exchange",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["7-alpha,27-Dihydroxycholesterol exchange",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["cholesterol 25-hydroxylase",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["cytochrome P450, family 46, subfamily A, polypeptide 1",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["oxysterol 7-alpha-hydroxylase",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["24 trihydroxy cholesterol transport",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["25 trihydroxy cholesterol transport",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["27 trihydroxy cholesterol transport",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["oxysterol 7alpha-hydroxylase",8,1.45,2,0.442,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid"]
["carnitine O-acetyltransferase, reverse direction, peroxisomal",8,1.45,2,0.442,1,1,"Docosahexaenoic acid\nAdrenic acid"]
["carnitine-acetylcarnitine carrier, peroxisomal",8,1.45,2,0.442,1,1,"Docosahexaenoic acid\nAdrenic acid"]
["N-acetyl-glucosamine lysosomal efflux",8,1.45,2,0.442,1,1,"D-Fructose\nD-Glucose"]
["N-acetylglucosamine kinase",8,1.45,2,0.442,1,1,"D-Fructose\nD-Glucose"]
["fatty-acid--CoA ligase",24,4.34,5,0.446,1,1,"Adrenic acid\n8,11,14-Eicosatrienoic acid\nLinoleic acid\nAlpha-Linolenic acid\nDocosahexaenoic acid"]
["fatty-acyl-CoA elongation (n-C18:3CoA)",3,0.543,1,0.452,1,1,"8,11,14-Eicosatrienoic acid"]
["fatty acyl-CoA desaturase (n-C20:3CoA -> n-C20:4CoA)",3,0.543,1,0.452,1,1,"Adrenic acid"]
["Succinate exchange",3,0.543,1,0.452,1,1,"Creatine"]
["Biotin exchange",3,0.543,1,0.452,1,1,"L-Lysine"]
["biotinidase (biotin), extracellular",3,0.543,1,0.452,1,1,"L-Lysine"]
["fatty-acyl-CoA elongation (n-C20:4CoA)",3,0.543,1,0.452,1,1,"Adrenic acid"]
["argininosuccinate lyase",3,0.543,1,0.452,1,1,"Creatine"]
["argininosuccinate synthase",3,0.543,1,0.452,1,1,"Creatine"]
["glycochenodeoxycholate exchange",41,7.42,8,0.474,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["carnitine O-aceyltransferase, mitochondrial",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["carnitine O-aceyltransferase, peroxisomal",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["carnitine-propcarnitine carrier, peroxisomal",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["cytochrome P450, family 7, subfamily A, polypeptide 1",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["taurine transport (sodium symport) (cytosol to peroxisome)",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["taurochenodeoxycholate exchange",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["transport into the mitochondria from cytosol (carnitine)",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Cytochrome P450 27",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["5-beta-cytochrome P450, family 27, subfamily A, polypeptide 1",42,7.6,8,0.506,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["fatty acid intracellular transport",42,7.6,8,0.506,1,1,"Docosahexaenoic acid\nTaurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nAdrenic acid\nOxalic acid"]
["NADP transporter, peroxisome",9,1.63,2,0.508,1,1,"Taurocholic acid\nGlycocholic acid"]
["NADPH transporter, peroxisome",9,1.63,2,0.508,1,1,"Taurocholic acid\nGlycocholic acid"]
["alpha-methylacyl-CoA racemase",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["alpha-methylacyl-CoA racemase (reductase)",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Chenodeoxyglycocholate exchange",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["FADH2 transporter, peroxisomal",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["glycocholate exchange",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Taurocholic acid exchange",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["acyl-Coenzyme A oxidase 2, branched chain",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["hydroxysteroid (17-beta) dehydrogenase 4",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["3-beta-hydroxysteroid-delta(8),delta(7)-isomerase",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["C-3 sterol dehydrogenase (4-methylzymosterol)",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["C-4 methyl sterol oxidase",44,7.97,8,0.569,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["peroxisomal thiolase 2",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["bile acid intracellular transport",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Very-long-chain-fatty-acid-CoA ligase",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["bile acid Coenzyme A: amino acid N-acyltransferase",45,8.15,8,0.599,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Proline dehydrogenase",34,6.16,6,0.611,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["acetyl-CoA carboxylase",17,3.08,3,0.626,1,1,"8,11,14-Eicosatrienoic acid\nDocosahexaenoic acid\nAdrenic acid"]
["24-dehydrocholesterol reductase [Precursor]",46,8.33,8,0.629,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Lathosterol oxidase",46,8.33,8,0.629,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["O2 transport, peroxisomal",5,0.905,1,0.635,1,1,"Oxalic acid"]
["protoporphyrinogen oxidase, mitochondrial",53,9.59,9,0.664,1,1,"Taurocholic acid\n8,11,14-Eicosatrienoic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["enolase",6,1.09,1,0.703,1,1,"Citric acid"]
["pyruvate kinase",6,1.09,1,0.703,1,1,"Citric acid"]
["C-14 sterol reductase",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["C-3 sterol keto reductase (zymosterol)",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["C-4 sterol methyl oxidase (4,4-dimethylzymosterol)",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["cholesterol precursor intracellular transport",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["cytochrome P450 lanosterol 14-alpha-demethylase",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["FAD transporter, endoplasmic reticulum",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["FADH2 transporter, endoplasmic reticulum",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["lanosterol synthase",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Previtamin D3 formation",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Squalene epoxidase, endoplasmic reticular (NADP)",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Squalene synthase",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Vitamin D3 exchange",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["Vitamin D3 formation",49,8.87,8,0.71,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["dihydroceramide desaturase",38,6.88,6,0.73,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["7-dehydrocholesterol reductase",50,9.05,8,0.735,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["citrate synthase",7,1.27,1,0.758,1,1,"Citric acid"]
["methionine synthase",7,1.27,1,0.758,1,1,"Creatine"]
["glutamine phosphoribosyldiphosphate amidotransferase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylaminoimidazole carboxylase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylaminoimidazole synthase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylaminoimidazolecarboxamide formyltransferase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylaminoimidazolesuccinocarboxamide synthase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylformylglycinamidine synthase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylglycinamide formyltransferase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["phosphoribosylglycinamide synthase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["adenylosuccinate lyase",14,2.53,2,0.759,1,1,"D-Fructose\nD-Glucose"]
["Beta oxidation of long chain fatty acid",52,9.41,8,0.78,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["taurine transport (sodium symport) (2:1)",40,7.24,6,0.78,1,1,"Chenodeoxycholic acid glycine conjugate\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["ATP synthase (four protons for one ATP)",22,3.98,3,0.802,1,1,"D-Fructose\nD-Glucose\nCreatine"]
["sterol 12-alpha-hydroxylase",42,7.6,6,0.823,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["sterol 12-alpha-hydroxylase (nadh)",42,7.6,6,0.823,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["pyruvate carboxylase",9,1.63,1,0.84,1,1,"Citric acid"]
["5,10-methylenetetrahydrofolatereductase (NADPH)",9,1.63,1,0.84,1,1,"Creatine"]
["glyceraldehyde-3-phosphate dehydrogenase",19,3.44,2,0.893,1,1,"Citric acid\nCreatine"]
["Glutamate transport via Na, H symport and K antiport",21,3.8,2,0.925,1,1,"Citric acid\nCreatine"]
["carboxylic acid dissociation",22,3.98,2,0.937,1,1,"8,11,14-Eicosatrienoic acid\nAdrenic acid"]
["hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7",37,6.7,4,0.939,1,1,"Palmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["R group artificial flux",14,2.53,1,0.944,1,1,"Linoleic acid"]
["phosphoribosylpyrophosphate synthetase",23,4.16,2,0.947,1,1,"D-Fructose\nD-Glucose"]
["adenosylhomocysteinase",16,2.9,1,0.964,1,1,"Creatine"]
["methionine adenosyltransferase",16,2.9,1,0.964,1,1,"Creatine"]
["glutamine synthetase",34,6.16,3,0.97,1,1,"D-Fructose\nD-Glucose\nCreatine"]
["glycine hydroxymethyltransferase, reversible",18,3.26,1,0.976,1,1,"Creatine"]
["phosphoglycerate dehydrogenase",23,4.16,1,0.992,1,1,"Creatine"]
["phosphoserine phosphatase (L-serine)",23,4.16,1,0.992,1,1,"Creatine"]
["phosphoserine transaminase",23,4.16,1,0.992,1,1,"Creatine"]
["Trehalose exchange",100,18.1,9,1,1,1,"Taurocholic acid\nD-Fructose\nD-Glucose\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nCitric acid\nGlycocholic acid\nCreatine\nOxalic acid"]
["L-Phenylalanine exchange",73,13.2,5,1,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nOxalic acid"]
["lipid, flip-flop intracellular transport",98,17.7,8,1,1,1,"Taurocholic acid\nChenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nGlycocholic acid\nPalmitoleic acid\nDocosahexaenoic acid\nAdrenic acid\nOxalic acid"]
["FAD transporter, peroxisomal",70,12.7,3,1,1,1,"Chenodeoxycholic acid glycine conjugate\nTaurochenodesoxycholic acid\nOxalic acid"]