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["Table S5-1 Detailed information of differential metabolites for metabolomics and transcriptomics integrated analyses"]
["Compound ID","Name","TM_1","TM_2","TM_3","TM_4","TM_5","TM-06T_1","TM-06T_2","TM-06T_3","TM-06T_4","TM-06T_5","TM-15T_1","TM-15T_2","TM-15T_3","TM-15T_4","TM-15T_5","TM-TP_1","TM-TP_2","TM-TP_3","TM-TP_4","TM-TP_5","TM mean","TM-06T mean","TM-15T mean","TM-TP mean","Log2 (TM-06T/TM)","P-value","FDR","Log2 (TM-15T/TM)","P-value","FDR","Log2 (TM-TP/TM-06T)","P-value","FDR"]
["NEG00057","Glucose",768329250.239205,911446622.587163,1024481884.88111,870050646.462224,1007561565.06658,925061716.78341,1085079520.52818,1069503353.8499,1270910914.52646,931120759.875191,1020412920.29452,1200895365.66972,1343369719.19778,1463836393.62593,1265486787.68652,1568997067.07852,1148631430.38814,1250214691.98773,1281455153.8158,1023215698.64248,916373993.847256,1056335253.11263,1258800237.29489,1254502808.38253,0.205059359446376,0.113434434179051,0.246426529423456,0.458040934206716,0.00449015333747637,0.0150771601071608,0.24804791947891,0.110731931758965,0.288373557490789]
["NEG00056","Glucose-6P",91577225.2264369,102469791.787062,80586203.1273613,95640636.9295615,70576855.8275978,41325732.1928497,53433499.8635489,36480596.6651268,41966479.5526692,55519134.0305861,22607651.0947956,27261280.9536169,27093168.8380946,24064982.8494541,25097520.1727932,71217160.8574056,80033987.8294503,93247803.2747407,100849566.247325,135326088.576099,88170142.5796039,45745088.4609561,25224920.7817509,96134921.3570041,-0.946673339639916,0.000238272086700497,0.0016837141292438,-1.80544045409886,{"v":4.14627344969141e-06,"d":"4.15E-06"},{"v":5.94432087835566e-05,"d":"5.94E-05"},1.07144373733546,0.0025455374649296,0.015345268302736]
["POS05490","Fructose-6P",4948.26920713037,3640.12027868005,8897.6927771254,14089.5840472024,5516.89035511603,134322.375859022,350840.973110027,135788.244758015,198990.915026897,488712.298875923,11932.1023766164,174631.061197106,315445.084060363,95727.5285644487,200202.673453878,646928.924768805,348574.341067246,608003.049861265,489772.684007361,530850.307545344,7418.51133305085,261730.961525977,159587.689930482,524825.861450004,5.14081107681875,0.00622745703879936,0.0235202011384628,4.42707584948835,0.0175764755937577,0.0480266190170301,1.00375421387606,0.016026288171463,0.0655860814189882]
["NEG00060","Fructose-1,6P2",20827529.4658104,25218065.1783993,18478668.2876046,19362309.3598915,17881876.1550265,17296778.3975854,14726497.9686317,10845954.0998469,15925873.5669545,19647740.5975013,5918954.05449648,9915492.48501124,13592019.5979971,11549736.4915151,9551819.25433252,39636026.9048037,28127934.7500467,34343100.7384014,47270651.5489429,64159406.95822,20353689.6893465,15688568.926104,10105604.3766705,42707424.1800829,-0.375576588903811,0.044919274169437,0.121698312150146,-1.01013474176035,0.000501031568015724,0.00234671644370087,1.44477312799828,0.00287305950354479,0.0166898638433193]
["NEG00027","Glycerate-3P",12884323.76,13903722.81,9592021.161,12999105.77,10890580.02,7367469.008,9319409.516,5414732.558,5758292.215,11857994.51,3178242.267,6088205.163,5967066.036,4644611.411,5097235.764,13426702.76,12566434.77,13733296.72,17731284.99,19597706.99,12053950.7042,7943579.561400001,4995072.1282,15411085.245999997,-0.6016448989884312,0.0209565826676977,0.0658195878058526,-1.2709286542639864,{"v":7.31875782091977e-05,"d":"7.32E-05"},0.000487880830595739,0.9561072888818243,0.00345658411644686,0.0193750636000837]
["NEG06632","Phosphoenolpyruvate",2197721.87867945,2411176.61522497,1627392.35740098,2146407.50131573,1846525.90678201,822985.089225248,1555825.454088,710615.212173988,776001.149097714,2067793.61595533,575466.591705506,952561.082532478,865793.771082465,605188.264354663,875506.081649521,1912384.39536636,1843824.42623674,1988771.70317701,2638680.00160023,3344055.21218619,2045844.85188063,1186644.10410806,774903.158264927,2345543.14771331,-0.785809431729686,0.0215812809747622,0.0675056432168612,-1.40060881213375,{"v":4.21977168834316e-05,"d":"4.22E-05"},0.000315109161301485,0.983034730660096,0.0184689287746585,0.07388786772425]
["NEG00706","Pyruvate",50786419.44,58142753.48,59162423.24,52310906.27,59321761.39,54052970.73,65707915.11,64517780.95,79673683.16,56296017.04,54571285.63,63491422.48,77621058.72,85432041.59,72515251.25,129761306,86704279.48,97227693.66,94412854.72,81174260.9,55944852.764,64049673.398,70726211.93399999,97856078.95199999,0.19518581261600862,0.134347096712297,0.27937450655235,0.3382395918548611,0.0316485440945315,0.078909664289208,0.6114702618062191,0.00779341985044263,0.0366947020958209]
["NEG00017","Citrate",277696396.499334,253963320.769907,233261792.430373,384138578.863015,201113562.72067,168134993.212573,230199430.236202,184400044.923978,236188402.56383,227792238.505957,135276177.544316,196984810.371004,221907518.615359,183018362.13526,199260683.473886,131478141.611993,117255527.034237,132269122.392919,107647556.584576,96278019.0075137,270034730.25666,209343021.888508,187289510.427965,116985673.326248,-0.3672761410712,0.112976642346998,0.245551273672558,-0.527874869592595,0.0425820117201728,0.101529498093994,-0.839536968279597,0.000331945169502535,0.00335543719425643]
["NEG00375","Malate",62977087.5974624,67032846.1769175,49004455.4690958,65274063.3604882,51992412.8474534,13783587.5850256,27336101.4503362,16776645.8144346,14183445.3400857,28692324.672386,9205819.6121899,10359184.2445186,9376298.69552708,8817472.51461224,11029972.5812178,21000142.308383,22829477.9743568,25498983.559438,29892305.742725,34241490.1929282,59256173.0902835,20154420.9724536,9757749.52961312,26692479.9555662,-1.55586912070814,{"v":4.45702546536396e-05,"d":"4.46E-05"},0.000459361172962512,-2.60234510000298,{"v":9.0555213013667e-07,"d":"9.06E-07"},{"v":2.24395332808139e-05,"d":"2.24E-05"},0.405337014394965,0.145144175599213,0.345162292698091]
["NEG00682","Fumarate",12993258.4150117,10658005.1089436,7329608.27897151,9050770.2184435,12391208.5058624,6338750.29453329,7225601.03608301,7094036.56492935,8565978.65217537,11013505.4954066,9149143.16632724,5692679.09768261,5442274.78348615,8373738.52402521,6739445.18078991,10157833.3981313,8634026.9638441,10182257.2417704,11144269.4146685,11471067.3210984,10484570.1054465,8047574.40862552,7079456.15046222,10317890.8679025,-0.381641792240122,0.104929994065171,0.230948520914057,-0.566557267730903,0.0285742039089271,0.0725794514960992,0.358522176160713,0.0457467962605891,0.149689407222835]
["NEG00583","2-oxoglutarate",8132598.568,8005147.67,5575867.203,7161240.751,9558450.716,5431430.478,8525530.302,5721708.433,6957635.308,9022487.348,4514724.535,6700083.228,6651655.28,5480644.138,6054785.583,11983889.16,8861722.244,9908832.232,10500865.85,11433015.17,7686660.9816,7131758.373799999,5880378.552800001,10537664.931200001,-0.10809921530418269,0.584403026845112,0.724711599411751,-0.38644800775061683,0.0469824574379494,0.110080049340343,0.563225481868633,0.00564974804579174,0.0287107454283502]
["NEG06565","Glucono-1,5-lactone-6P",213595.565353949,465801.003669706,214365.618342918,374606.251574878,210907.991729264,104542.438424897,150095.49006963,67520.9732970441,191610.079544028,197643.079547364,22596.0219491185,49554.6935809466,9904.94803333202,36700.7678402538,22391.2877832446,185788.262741909,281482.300036401,239880.51024359,367549.659226228,602502.494691432,295855.286134143,142282.412176593,28229.5438373791,335440.645387912,-1.05613433401226,0.0302549757540504,0.0888578506551985,-3.38961395087163,0.00101513452642526,0.0042199783798329,1.23730017267921,0.036925413097994,0.128001473013177]
["NEG00042","Gluconate-6P",5689617.02802954,7700838.77185179,6386856.28978279,9395627.3161403,7593358.12570208,1099378.6847184,1133714.23910594,670365.40672685,763799.605836787,1419524.09216819,179358.327048076,323403.262850108,377833.989001225,333996.6718114,369213.001263681,3784354.9798705,3799262.5393612,5088734.85401019,6789475.36059163,7899170.22737488,7353259.5063013,1017356.40571123,316761.050394898,5472199.59224168,-2.85355872009844,{"v":1.0126569790903e-05,"d":"1.01E-05"},0.000157831771158987,-4.53691704583115,{"v":3.94800658208733e-06,"d":"3.95E-06"},{"v":5.73256869911059e-05,"d":"5.73E-05"},2.42729567148897,0.00067314827474655,0.00555424769761579]
["NEG06543","Ribose-5P",3120705.15301161,3540000.27073839,2735320.38539292,3176614.8634706,3105283.33336046,1282647.53178043,2177225.85446115,1226457.49500523,1453234.152805,2519299.07874185,964685.522458173,1215197.37152267,1159499.69503836,908927.785194245,1116532.73008461,4258527.57082737,4666179.05099534,5485190.72342433,7568767.29614881,10426247.7654174,3135584.8011948,1731772.82255873,1072968.62085961,6480982.48136265,-0.856484850637483,0.00128188117073368,0.00647893161208108,-1.54712665261574,{"v":4.55417928286003e-07,"d":"4.55E-07"},{"v":1.47614811103137e-05,"d":"1.48E-05"},1.90396284749593,0.00361831598356864,0.0201302579533614]
["NEG06557","Sedoheptulose-7P",1524849.94882636,1788415.03835593,1202656.1765647,1571036.50422083,1239685.06473507,677072.382400768,871042.437883547,586818.64425738,652365.530869395,1027625.47638669,1102648.99671307,352256.47628152,371067.040635263,337062.033631386,360393.199951211,1352267.45958418,1485786.35082463,2059938.50283292,2430292.24824997,3247172.07416031,1465328.54654058,762984.894359556,504685.54944249,2115091.3271304,-0.941497772862964,0.000869877727488826,0.00465983601803296,-1.53776748876782,0.000837828275109008,0.00357595980397194,1.47099355869294,0.00502711305739951,0.0262086905255674]
["POS04206","Erythrose-4P",1279169.16063031,534987.744565009,428666.097322589,1012349.87328786,843187.230245676,255871.891560729,315266.453621106,365930.469677188,512015.226681783,507908.238940471,110854.748118171,516665.000211708,125911.773269331,469253.088367779,195343.268084583,181506.495534064,363860.404118592,413834.207551413,482194.030790525,153714.317681427,819672.021210289,391398.456096255,283605.575610314,319021.891135204,-1.06640868845453,0.03079957444441,0.0901768797272551,-1.53116085774227,0.0167935315838047,0.0464548341214338,-0.294982640689471,0.407006922400359,0.623779389587033]
["NEG00641","Shikimate",2191928.34663919,1918935.46835382,2175661.11012915,2059968.57073079,1969936.34453051,2058897.94876335,2143379.24604154,1930949.25427468,2171275.24153171,2049696.98369814,1832270.15693118,1985420.77922542,1906075.29357833,2044504.85102942,2233480.7108533,2355025.57458175,2709193.68783541,2585535.91539618,2527937.11903142,2653086.01333803,2063285.96807669,2070839.73486188,2000350.35832353,2566155.66203656,0.00527211545645856,0.915089368207395,0.952640439624181,-0.044691082292745,0.491455198627681,0.644554130480168,0.309392780696906,0.000155770950925404,0.00205037568835903]
["NEG04929","Chorismate",509372.119293465,614585.973342917,531711.99390879,592758.251148715,576621.958113249,580128.550611187,603331.688023499,573062.403308808,608416.807919372,590194.782075931,572014.01992278,588121.675413495,588896.978256412,610641.364754766,561485.393371733,612740.385197632,604969.430619302,599265.739844467,618269.923130775,599277.037455981,565010.059161427,591026.846387759,584231.886343837,606904.503249631,0.0649471110659939,0.241554924625903,0.415055645121933,0.0482645472715628,0.390537751780016,0.557218836884086,0.0382458616415959,0.0725074835214762,0.213468202273244]
["NEG00724","3-dehydroshikimate",207335.47031044,309835.506547509,252637.42078247,187416.192916992,230928.229329496,183638.147791522,259559.033726194,250353.126619573,288002.502933206,319492.873732912,224321.221374979,401667.286913584,300814.307401973,279883.539612455,271137.612533754,215678.212957279,278888.628493194,239164.934737981,303448.807544379,301379.677719182,237630.563977381,260209.136960681,295564.793567349,267712.052290403,0.130951214501629,0.486631809938517,0.644758319269841,0.314754024854712,0.147621686802381,0.280506289323301,0.0410104683876726,0.799368563665832,0.893670478699642]
["NEG00552","3-dehydroquinate",3451021.19887065,3057659.40753193,3658289.46369481,3218808.65779992,1943030.54616641,1654947.04065412,2910249.85942418,2937672.33017796,1775558.59463516,933711.136956088,2947134.73312551,2922182.49208419,1056112.15788519,2995037.15226488,2891293.52484434,3217609.15165179,4362557.92553224,3081391.96870374,3040749.42990778,3081843.77929727,3065761.85481274,2042427.7923695,2562352.01204082,3356830.45101856,-0.585960559813639,0.0698733230244739,0.170230595799821,-0.258776949745559,0.325780006409385,0.496495389665819,0.716814595806188,0.0218503021620734,0.0851362383022249]
["NEG00680","3-hydroxyanthranilate",1709773.32153418,1680919.55130961,1607618.51905825,1663810.27582275,1679924.25137,1588110.77547349,1765708.11094763,1736404.8739635,1694622.88982701,1578747.33445763,1651599.20998387,1778578.32124223,1763540.48422782,1765290.55718513,1689607.1896308,1672355.50515519,1919900.87866086,1822294.57264866,1976438.7978591,1827801.22238355,1668409.18381896,1672718.79693385,1729723.15245397,1843758.19534147,0.00372177357643532,0.920356839193921,0.956051124411149,0.0520679898017986,0.0767201409381371,0.16572982413396,0.140454529722126,0.0287887829597609,0.105970492650687]
["NEG00165","Anthranilate",1397513.70967117,3451874.917874,2226818.68574016,2252186.08685431,1801955.67384787,2279903.79357642,3592817.83932605,1215717.1262406,2395972.70271396,3480308.62185133,828063.71325141,2699761.086605,1557101.1574509,2756259.75855879,2715770.82868748,1548610.72468013,1569450.37877535,1423595.1796632,2887732.24278479,2057990.69922243,2226069.8147975,2592944.01674167,2111391.30891072,1897475.84502518,0.220092218145831,0.528136961092749,0.68023179126969,-0.0763048583181207,0.831636193147229,0.900429208633396,-0.450509537684792,0.212915198044881,0.439487623836988]
["POS00137","Glutamate",671459248.8,641950430.7,581106582,733654487.1,719806560.2,1666014072,2059219250,1808695247,1872428501,1881506816,1423715971,1881560639,1891315002,1788934288,1799034499,1722572554,1679618703,1874380758,1734481321,1757634997,669595461.76,1857572777.2,1756912079.8,1753737666.6,1.4720570796740107,{"v":1.34745600508934e-07,"d":"1.35E-07"},{"v":1.1817981785813e-05,"d":"1.18E-05"},1.3916803420997188,{"v":2.06732359273031e-06,"d":"2.07E-06"},{"v":3.72868485092044e-05,"d":"3.73E-05"},-0.082985776789454,0.18392232644806,0.401113879181947]
["NEG06201","Glutamine",1070884.557,904813.4678,574502.9157,955146.6789,640314.8565,12432524.26,13429713.35,9161316.334,11532687.94,18507961.13,10266392.32,12948643.41,13969160.85,10216925.4,11987971.19,17869553.3,19385125.76,20843399.04,22739481.78,26963833.88,829132.49518,13012840.6028,11877818.634,21560278.751999997,3.972189452940333,{"v":4.90475523527851e-05,"d":"4.90E-05"},0.000499748750965849,3.8405234362602347,{"v":4.16124106753449e-07,"d":"4.16E-07"},{"v":1.41009327993044e-05,"d":"1.41E-05"},0.7284399051176221,0.00469170031198401,0.0250429301855662]
["NEG06053","Omithine",399612.4418,420174.7248,462026.0323,281158.6032,311785.9402,16724037.21,22448151.87,16636751.65,15505336.48,17311885.69,15158356.46,17904260.32,18214327.42,16371691.28,16745781.3,21265699.3,22943808.59,26919368.35,24106225.4,31296097.79,374951.54846,17725232.58,16878883.356,25306239.886,5.562956566111694,{"v":5.70593747441931e-07,"d":"5.71E-07"},{"v":2.93363888771007e-05,"d":"2.93E-05"},5.492371472209522,{"v":1.69744656712873e-09,"d":"1.70E-09"},{"v":7.59267849476681e-07,"d":"7.59E-07"},0.5136886035296409,0.00755488702441363,0.0358736832910851]
["POS00348","Arginine",237366.5292,330595.2652,277305.2295,201146.6209,173525.2681,3507292.842,14116838.68,14377522.96,12823968.99,9785308.148,16101231.24,19692732.74,18861110.11,18629185.55,17222682.15,18810433.22,18475237.04,20653624.84,19519178.64,17813861.23,243987.78257999997,10922186.324000001,18101388.358,19054466.994,5.484308954935717,0.000753501377711448,0.00415587134710642,6.2131476363345515,{"v":2.91629550037806e-09,"d":"2.92E-09"},{"v":1.00342998255316e-06,"d":"1.00E-06"},0.8028675791652492,0.00451328162827503,0.0243521214997276]
["NEG05879","Proline",515473.4553,456447.2828,559677.4167,514296.813,579023.1184,2239468.548,3972945.49,2759953.491,2553154.508,2871294.188,993421.2065,1164332.429,1301923.495,1147832.766,1192833.038,2278499.301,2746839.932,2315102.633,2725901.364,3565667.189,524983.6172399999,2879363.245,1160068.5869,2726402.0838,2.4554054955200004,{"v":4.39346065278539e-05,"d":"4.39E-05"},0.00045385564664917,1.1438657970192445,{"v":2.47322861440352e-06,"d":"2.47E-06"},{"v":4.1733839515031e-05,"d":"4.17E-05"},-0.07875145970483749,0.693442404611124,0.831350274946544]
["NEG06263","Serine",1113496.483,1039575.904,790437.1366,1191266.406,839731.9981,2049222.64,2379511.046,1358303.725,1736047.959,2663555.094,1326986.716,1650715.188,1757892.39,1407441.928,1594458.739,2746265.228,2751423.06,3139446.368,3318336.403,5048430.925,994901.58554,2037328.0928,1547498.9922,3400780.3968,1.0340526034930522,0.00265695198164088,0.0116515158959604,0.6373127417123555,0.00107419198018142,0.00444072155947457,0.7391875162785451,0.0227640822116999,0.0878548228929538]
["NEG00203","Alanine",881088.8622,1401765.568,1125482.017,1612241.948,1227714.909,11100385.14,12917465.01,8286478.435,11482548.72,13701421.86,11476286.15,15694466.36,18000854.12,13370208.9,14685390.63,33617315.13,35285213.59,38326066.91,36572953.82,42476658.35,1249658.66084,11497659.833,14645441.231999999,37255641.559999995,3.201734265716681,{"v":4.4161975676096e-06,"d":"4.42E-06"},{"v":9.28514258245561e-05,"d":"9.29E-05"},3.550845671261536,{"v":1.95788191102104e-06,"d":"1.96E-06"},{"v":3.58918269999882e-05,"d":"3.59E-05"},1.696118653767423,{"v":5.0783308457928e-07,"d":"5.08E-07"},{"v":6.20487680556787e-05,"d":"6.20E-05"}]
["NEG00196","Valine",3903948.329,3646465.538,3183586.126,3445001.725,3435780.882,21869031.4,26323651.36,18199720.85,28625588.72,25014904.86,21789054.14,29976645.02,36988713.51,31366033.11,33295505.71,65057647.61,56691553.05,66861152.05,55710805.64,63067924.6,3522956.5200000005,24006579.438,30683190.297999997,61477816.589999996,2.7685712822903628,{"v":3.49941151106003e-06,"d":"3.50E-06"},{"v":8.03850402576802e-05,"d":"8.04E-05"},3.1225899210334203,{"v":4.82998563927878e-06,"d":"4.83E-06"},{"v":6.54682598924059e-05,"d":"6.55E-05"},1.3566360712909717,{"v":1.17135963335978e-06,"d":"1.17E-06"},0.000103713930988728]
["NEG00159","Leucine",7348393.49,7084991.472,7954111.828,7465908.936,7006984.755,15524078.94,19431933.55,14049627.87,19672087.85,18529485.42,12670457.76,14145428.04,16864171.26,14932450.33,14081560.5,29273084.27,26696234.21,29808743.21,31918126.42,40096145.5,7372078.0962,17441442.726000004,14538813.578,31558466.722000003,1.2423761229214356,{"v":2.0891575401213e-05,"d":"2.09E-05"},0.000263233850055283,0.9797662853365798,{"v":7.62181608145799e-06,"d":"7.62E-06"},{"v":8.97167982430568e-05,"d":"8.97E-05"},0.8555077309718867,0.000552627864891581,0.00480915260634249]
["NEG00445","Oxaloacetate",3095563.226,579855.6192,3558931.899,2285211.281,2237092.151,427797.3814,398719.8108,392097.7167,513627.5722,2662274.98,2416997.898,1451120.334,366837.4762,562918.4051,2536026.097,407929.8076,457675.7456,4154924.851,544982.6127,488125.8146,2351330.83524,878903.49222,1466780.0420600001,1210727.7663,-1.4197008778935603,0.0611870771325935,0.152899327382174,-0.6808250012288285,0.229379038330854,0.389378534517612,0.46209784524898273,0.710024955208383,0.841992209863386]
["NEG06473","Aspartate",2247950.396,1532767.905,1537774.436,1217478.615,1189163.924,965110.8035,1248495.809,1176233.054,1188853.609,1359497.39,1351553.326,1253438.537,1183540.899,1329450.171,976182.1097,1066785.871,1085837.272,1136717.554,1014212.188,1383464.381,1545027.0552,1187638.1330999997,1218833.00854,1137403.4531999999,-0.3795367798624541,0.11387535036035,0.246904722327604,-0.3421316247427715,0.145726694850265,0.277849746830876,-0.06235123225091016,0.596701205300983,0.770848305881193]
["NEG06241","Asparagine",954284.3444,899842.1379,642136.7365,1222982.45,805976.8681,2300092.611,2910517.766,1897399.596,1963781.078,3279208.56,1547099.577,1654083.305,1832764.963,1369338.967,1724294.781,3373961.138,3218235.635,4032778.421,4009549.774,5939291.133,905044.50738,2470199.9222000004,1625516.3186,4114763.2202,1.4485671625776473,0.000602574201236034,0.00346887310441285,0.8448373928764394,0.000401544141877243,0.00195867715007296,0.7361816055845417,0.0180624237043037,0.0725253332399916]
["NEG00526","Tryptophan",1578573.49583056,1999646.11361719,1923886.32775267,1759512.97086366,1749284.33754873,638403951.839333,776982180.939327,751372081.620703,983178935.220926,640531593.558442,1465559913.99564,2030875213.81466,2351121628.99543,2516170345.70128,2124531397.13461,1234707464.12348,793962616.697518,1000421429.68321,1037947388.38821,823631457.4498,1802180.64912256,758093748.635746,2097651699.92832,978134071.268444,8.71648882515233,{"v":2.1203787931426e-06,"d":"2.12E-06"},{"v":6.05888685336496e-05,"d":"6.06E-05"},10.1848158002855,{"v":2.63598176232477e-06,"d":"2.64E-06"},{"v":4.28356980064942e-05,"d":"4.28E-05"},0.367655958271614,0.0624607086813638,0.190968386829624]
["NEG04415","Indole-3-pyruvate",782102.93956031,610775.634698577,624351.340513867,840554.960517834,584039.457333937,4743793.52305133,7249333.54216602,7902235.47204525,12469096.8113405,3284214.42677688,7014051.88851819,12930410.0598801,20442272.1864547,18315435.902909,15562283.6064218,6257361.91979862,3697044.57960225,4883119.61236226,4917180.43005351,3133774.6073278,688364.866524905,7129734.755076,14852890.7288368,4577696.22982889,3.37260303499535,0.00349491604347232,0.0146648775445138,4.43142646568951,0.00029942602267076,0.00153066582789293,-0.639226674970262,0.164031120285578,0.372280051518312]
["NEG00059","Indole-3-acetaldehyde",3360950.20948853,3646985.63059885,3664744.23518897,3552466.86112147,3666473.87732486,13031010.2251544,11847611.9761857,11729751.9434208,22224485.8168515,12257603.5477798,14559023.0125227,22832066.1689488,21939927.2231969,18498838.1372592,15322771.1588271,12368116.2309401,11735872.4512589,14996281.7208631,9262342.90053857,5228935.96108136,3578324.16274454,14218092.7018784,18630525.1401509,10718309.8529364,1.99037195326791,0.000746815210110187,0.00412917729891578,2.38031234709959,{"v":1.88567944117123e-05,"d":"1.89E-05"},0.000171785013041933,-0.407650518110807,0.215602450765956,0.442177791048199]
["NEG00066","Tryptophol",13129.2549656401,31833.3322983961,30714.7282349636,12669.336861809,21049.7202112537,5510257.17789544,6326842.61382043,3770901.51391083,5309198.63487336,6835686.78982939,1569558.00712721,2664764.10487789,2933155.72721631,2477059.27379083,2449170.67268872,1784334.91552104,1358914.0003887,1825395.86710322,2107656.43586071,2431950.80866382,21879.2745144125,5550577.34606589,2418741.55714019,1901650.4055075,7.98692913047496,{"v":5.64104663206653e-06,"d":"5.64E-06"},0.000105579522724333,6.78854791395857,{"v":6.07812245685547e-06,"d":"6.08E-06"},{"v":7.68006829082331e-05,"d":"7.68E-05"},-1.54538579266153,0.000169937373840518,0.00215945986701318]
["NEG05027","Tryptamine",648228.904428931,547124.202231414,581825.340321204,702775.101444755,622110.258047524,1055764.38717652,1347141.5036419,1320824.06466602,1600215.57617894,975449.755452537,2596652.53625138,3430248.74840157,4122031.26315778,4510803.90586386,3697278.28341191,2152065.15474254,1348795.67069752,1667397.68849066,1838208.67832655,1396036.26562859,620412.761294766,1259879.05742318,3671402.9474173,1680500.69157717,1.02198498166077,0.00053195073157988,0.0031266959557908,2.56503119656489,{"v":1.41440632836722e-05,"d":"1.41E-05"},0.000141535559435941,0.415605888054653,0.0530807311884154,0.169109765388734]
["NEG05953","Indole-3-acetonitrile",91210.0185483547,126088.59938232,111351.476052139,106040.324671239,111168.670515909,910811.097883777,1955564.86546924,1869012.5709424,2207731.78550149,1482413.99392794,2236053.14810005,4103852.80654751,4395614.21216149,4216611.21996581,4021798.38538118,4498593.36018889,4375432.83539993,3708623.50354905,5674463.52996501,4708793.20230894,109171.817833992,1685106.86274497,3794785.95443121,4593181.28628236,3.94816769943706,0.000115634224250833,0.000959613886964705,5.11934612764142,{"v":1.41315610684827e-05,"d":"1.41E-05"},0.000141535559435941,1.44665364152423,{"v":7.2195729683813e-05,"d":"7.22E-05"},0.00124204422644498]
["NEG00144","Indole-3-acetic acid",970262.485848983,1833815.24214185,1856898.03089219,977228.100330969,1241741.10715998,1812241.17752309,2649662.43750689,2447445.65450549,4230651.78412613,2494638.28910519,1619045.67108553,3590667.31430201,3195402.35296946,3384795.74905404,2955288.89669319,1924779.29513353,2607338.47415943,1902418.66580951,2899312.60618495,2422407.75846196,1375988.99327479,2726927.86855336,2949039.99682085,2351251.35994988,0.986807609479517,0.0167148275778943,0.0544144277699571,1.09977645954164,0.0043921870398885,0.0148273604750349,-0.213847761054641,0.424734685856411,0.638002433940035]
["NEG04844","Indole-3-acetamide",777703.972007435,662544.814034621,679409.637871152,854345.154938526,742606.722284558,774077.75482651,64555.5885595937,59905.8688950112,113882.485845986,63242.8256340889,825729.832887218,95099.8000569967,81275.4064419722,94695.519268539,708334.853897852,807865.312964887,656335.475492561,751093.595124525,684996.379319295,697804.706850556,743322.060227258,215132.904752238,361027.082510516,719619.093950365,-1.78875922177613,0.00640521679509725,0.0240356834936829,-1.04188035959461,0.0551019266430115,0.126330557598252,1.7420052637058001,0.0076579559150895,0.0362860559408849]
["NEG05037","Indole",192106.86277439,233014.488649689,222551.831205742,205952.261822928,207058.045352078,3264733.74946199,4211260.5621248,4074783.89649119,5453649.81848234,3337036.11506445,8262315.396657,12997912.1618416,15175520.7283093,16085625.1113153,13225540.2416879,6801232.31391233,4131318.03477206,5364078.12862517,5554726.06266756,4311854.78830621,212136.697960965,4068292.82832495,13149382.7279622,5232641.86565667,4.26135740316554,{"v":1.01622065937376e-05,"d":"1.02E-05"},0.000157831771158987,5.9538570491646,{"v":1.18809313536019e-05,"d":"1.19E-05"},0.00012474977921282,0.3631159953821,0.0985641629704619,0.264415293305405]
["NEG05192","5-hydroxy-tryptophan",405484.905326985,772503.766203873,706090.55737525,406343.742963733,596217.873381284,1191163.62315071,1599816.0916606,1392465.1637764,2484044.18168597,1246884.64219541,2381979.47462782,3300392.13714582,3578981.21602334,3725603.53913331,3292263.42735802,2112627.05840215,1375918.36332165,1024554.16913496,2004688.93408962,1535969.87096053,577328.169050225,1582874.74049382,3255843.95885766,1610751.67918178,1.45508356920496,0.00364970200804225,0.0151861554250911,2.49556803367755,{"v":4.41891757166079e-06,"d":"4.42E-06"},{"v":6.1768182181371e-05,"d":"6.18E-05"},0.0251870052531512,0.930636243478008,0.968979496526333]
["NEG06097","5-hydroxy tryptamine",183769.081535823,272004.967097877,342697.215852098,249115.786327876,386232.375898391,995853.181710787,852341.250788425,505702.10162804,1294351.95916756,737094.799589711,1100360.62343244,424114.201565999,996323.078390309,675041.465330478,618768.480299247,581790.236433275,686079.472020425,1159393.68359686,895383.462089868,1263616.92194965,286763.885342413,877068.658576905,762921.569803695,917252.755218016,1.61282643955095,0.00251012608173223,0.0111011110739288,1.41167140770828,0.00632111414333294,0.020124087945287,0.0646295490471532,0.834300325910215,0.917194192875298]
["NEG04933","5-hydroxy-indole-3-pyruvate",3078330.96975056,3595931.00361106,3548331.39597937,3375953.42035179,3617238.14160356,937631.219117049,196554.000984523,934715.573737819,398963.675879516,942167.655575098,907292.143971905,376417.523707896,417331.906715141,328014.076808796,270634.786562489,950798.629368084,3519494.85256325,897680.356539537,1034909.94914836,3472123.12381034,3443156.98625927,682006.425058801,459938.087553245,1975001.38228591,-2.33587472441483,{"v":4.74216222444816e-07,"d":"4.74E-07"},{"v":2.77280564190125e-05,"d":"2.77E-05"},-2.90422038260381,{"v":4.82128798311525e-08,"d":"4.82E-08"},{"v":4.3131242296949e-06,"d":"4.31E-06"},1.53399642722518,0.0786317237490617,0.22546645875279]
["NEG04778","5-hydroxy-indole-3-acetic acid",118905.318703649,120347.524756534,124444.700775142,145302.676040897,129426.26649405,129290.722198627,212973.996825655,199990.189781944,214586.950614457,204937.972211325,203041.894386328,334389.974258634,294150.972766368,309217.234269413,203758.950052123,134390.968104919,112763.737067619,126669.752620094,246245.57523745,324360.242695217,127685.297354054,192355.966326402,268911.805146573,188886.05514506,0.59118616671987,0.00470187052334842,0.0186614612696872,1.07454067863393,0.000978570449159826,0.00409079029821673,-0.0262623824762856,0.939600040126619,0.974908601133464]
["NEG05202","N-formylkynurenine",16145.067783112,17789.5004809033,13692.6934531874,16819.1787454118,13946.4060689314,111512.836751017,160171.36475419,174970.346552536,88872.3508410451,72250.6327822442,318348.17690994,186341.639671482,190297.141861536,235974.377823926,200125.74775933,158981.486862289,141250.276204108,157520.997089806,124287.421379961,92631.4256565661,15678.5693063092,121555.506336206,226217.416805243,134934.321438546,2.9547494249915,0.000721354551282929,0.00400822224582427,3.85084418635737,{"v":2.72206264286707e-05,"d":"2.72E-05"},0.000223791155317532,0.150642106593958,0.583608343121136,0.761072920927358]
["NEG05389","Kynurenine",649961.965154647,708945.37043377,792493.235157217,651142.032146314,756387.295831572,670035.739306165,136420.689407448,106083.725286202,92237.0634517438,124414.993421061,90897.2304623825,120346.81988836,125074.882543575,103004.925318262,125403.879153967,666660.215307579,105576.551187486,166868.844866516,221224.89222713,385424.975228123,711785.979744704,225838.442174524,112945.547473309,309151.095763367,-1.65615243366818,0.00287137272078168,0.0124574686518491,-2.65581611785399,{"v":3.2681209712742e-08,"d":"3.27E-08"},{"v":3.39960583825802e-06,"d":"3.40E-06"},0.453021036858158,0.594130538138177,0.769013999986804]
["POS00177","Kynurenate",2097345.82261644,1215741.70894612,147437.673046302,2248339.62276785,120674.146448555,9825933.60800662,12905914.2073424,12703464.9829273,16003206.6405246,12056760.0695448,7954936.25599521,12858903.4506207,15384466.8715899,14656465.0800361,13501829.1738302,16132043.4161232,9569136.72315896,11545345.5430612,13107073.6121539,12830988.4140171,1165907.79476505,12699055.9016691,12871320.1664144,12636917.5417029,3.44519564194949,{"v":5.59271616282838e-06,"d":"5.59E-06"},0.000105553668338951,3.46463442999939,{"v":2.90117419289878e-05,"d":"2.90E-05"},0.000233543393740826,-0.00707664804895651,0.967123077252581,0.984081590601786]
["NEG00161","Phenylpyruvate",2317816.97953819,2651881.46653806,2893683.50377848,2430427.59112417,2191547.72226791,1835342.94598968,2132174.63648833,1735365.35349796,2817995.83525822,2188816.4028183,2032732.89764821,2507067.62569286,1948490.04841204,3747801.17863368,2463737.35271457,6496007.30560921,3597125.34071553,5286268.04994149,4745135.48385836,3246040.06093253,2497071.45264936,2141939.0348105,2539965.82062027,4674115.24821142,-0.221319686171842,0.156207953644648,0.31081769424044,0.0245719793464203,0.904191555538609,0.947400674213378,1.12577588884717,0.00342288648153411,0.0192343859697262]
["NEG00053","Phenylalanine",32806522.6922072,3608370.77479138,2357147.31422264,19490703.0469001,2399363.0070369,5602790.55118838,6817956.74383225,4909197.81364518,6709239.51335017,7220453.36612932,4546451.01371591,4619341.72635707,5264964.00799491,5540243.72813909,4822033.54069901,1970517863.41426,1236019781.7986,904562457.268356,1515934423.58705,1002542571.27157,12132421.3670316,6251927.59762906,4958606.8033812,1325915419.46797,-0.956494533726187,0.364489020740907,0.5384278037563,-1.29086077433563,0.273700624587111,0.44213177817918,7.72847196224901,0.000130695231061956,0.00187371720685939]
["NEG05423","4-hydroxy-phenylpyruvate",563249.53218295,628104.511754468,949962.662755613,610283.429072304,1174610.9537832,521276.134357761,1143640.05172263,890155.962536064,993783.761400048,480051.597454649,509498.509404332,530561.199178384,807181.273526331,919910.889453343,842229.186576036,3005674.76581971,1261547.26665279,1691045.3991425,1676082.35414259,1376978.30160128,785242.217909707,805781.50149423,721876.211627685,1802265.61747177,0.0372509453789134,0.910508380617849,0.950577407532532,-0.121386277317018,0.675635540923959,0.788033610724737,1.16135106016093,0.0186323913459976,0.0743831707638882]
["NEG04607","Tyrosine",932246.870695658,731821.60830394,726167.742836495,783546.505130388,713948.296751616,1757016.90216317,2026808.37922792,1420437.72013285,2215249.09003258,1928246.25893513,1624441.48834983,2219239.20719738,2329933.25641478,2321826.39846536,2143777.72019323,9288674.76252753,7935226.23749294,7892254.70946038,11137204.2011275,11016467.232155,777546.204743619,1869551.67009833,2127843.61412412,9453965.42855267,1.26569203119958,{"v":5.37195259144473e-05,"d":"5.37E-05"},0.000532788114002933,1.45239181054421,{"v":9.25675997409601e-06,"d":"9.26E-06"},0.000103255579461674,2.33822724451831,{"v":5.83617605953514e-06,"d":"5.84E-06"},0.000276520456839552]
["−","Glyceraldehyde-3P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Glycerate-2P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","3-deoxy-D-arabino-heptulosonate-7P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Acetyl-CoA","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Isocitrate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Succinyl-CoA","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Succinate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Ribulose-5P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Xylulose-5P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Shikimate-3P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","3-dehydroquinate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","5-hydroxy-indole-3-acetaldehyde","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Indole-3-glycerol phosphate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Indole-3-acetaldoxime","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","Prephenate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","5-enolpyruvoyl-shikimate-3P","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
["−","2-oxoisovalerate","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−","−"]
[]
["−","Not detected"]

{"sheet":"Table S5-2","index":2,"n_rows":84,"n_cols":28,"rows_kept":84,"merged":[[0,0,0,27],[2,0,8,0],[9,0,22,0],[23,0,26,0],[27,0,34,0],[35,0,42,0],[43,0,53,0],[54,0,64,0],[65,0,67,0],[68,0,79,0],[80,0,83,0]],"flags":["formulas_cached_only"]}
["Table S5-2 Detailed information of differentially expressed genes for metabolomics and transcriptomics integrated analyses"]
["Pathway","Gene ID","TM_1 fpkm","TM_2 fpkm","TM_3 fpkm","TM-06T_1 fpkm","TM-06T_2 fpkm","TM-06T_3 fpkm","TM-15T_1 fpkm","TM-15T_2 fpkm","TM-15T_3 fpkm","TM-TP_1 fpkm","TM-TP_2 fpkm","TM-TP_3 fpkm","TM mean","TM-06T mean","TM-15T mean","TM-TP mean","log2 (TM-06T/TM)","P-value","FDR","log2 (TM-15T/TM)","P-value","FDR","log2 (TM-TP/TM-06T)","P-value","FDR","Gene description"]
["Glycolysis",1820,3018.21,2894.08,1890.78,45.74,50.62,44.47,57.78,67.26,71.64,17.67,40.21,25.04,2601.02333333333,46.9433333333333,65.56,27.64,-5.79201524347539,{"v":2.16452627602035e-173,"d":"2.16E-173"},{"v":3.61410296390065e-171,"d":"3.61E-171"},-5.31011967684559,{"v":1.48727833454393e-105,"d":"1.49E-105"},{"v":2.08790996964821e-103,"d":"2.09E-103"},-0.764162672081404,0.49894814991571,0.673623239,"HXK1/Hexokinase isoenzyme 1"]
[null,1973,6821.26,6353.98,5364.95,5403.1,7342.08,5273.14,5901.08,5408.66,6595.92,13341.45,13012.32,13414.03,6180.06333333333,6006.10666666667,5968.55333333333,13255.9333333333,-0.0411915259974372,0.337098904909448,0.382341491570823,-0.0502403316223048,0.549666747981149,0.659238870798859,1.14213625002659,{"v":1.13554916206334e-13,"d":"1.14E-13"},{"v":5.95e-12,"d":"5.95E-12"},"GLK1/Glucokinase"]
[null,2097,683.01,691.42,674.24,157.43,117.45,173.25,135.4,151.59,83.51,45.84,50.18,44.82,682.89,149.376666666667,123.5,46.9466666666667,-2.19269839772697,{"v":9.46956130860182e-67,"d":"9.47E-67"},{"v":2.91493200058078e-65,"d":"2.91E-65"},-2.4671421659364,{"v":1.78406490704572e-39,"d":"1.78E-39"},{"v":7.28936967617561e-38,"d":"7.29E-38"},-1.66986017842686,{"v":2.05790555390104e-16,"d":"2.06E-16"},{"v":1.75e-14,"d":"1.75E-14"},"PFK1/Alpha subunit of heterooctameric phosphofructokinase"]
[null,3393,890.03,810.61,756.32,281.62,241.83,316.31,211.84,251.94,183,152.21,146.72,132.28,818.986666666667,279.92,215.593333333333,143.736666666667,-1.54882539488594,{"v":1.12274089805753e-27,"d":"1.12E-27"},{"v":7.98232561070582e-27,"d":"7.98E-27"},-1.92552739741192,{"v":1.41836563983554e-40,"d":"1.42E-40"},{"v":6.11460777803116e-39,"d":"6.11E-39"},-0.961586435031888,{"v":8.49722228487565e-07,"d":"8.50E-07"},{"v":8.95e-06,"d":"8.95E-06"},"PFK2/Beta subunit of heterooctameric phosphofructokinase"]
[null,1772,5739.85,4453.77,4463.19,10731.96,13297.84,10192.62,10283.44,10107.01,11517.25,6267.48,5225.7,7414.91,4885.60333333333,11407.4733333333,10635.9,6302.69666666667,1.22337064154914,{"v":3.07877026240602e-14,"d":"3.08E-14"},{"v":1.11239502595785e-13,"d":"1.11E-13"},1.1223334782572,{"v":5.94323353228352e-12,"d":"5.94E-12"},{"v":5.09220713446827e-11,"d":"5.09E-11"},-0.855938145131741,0.133061045418463,0.275781787,"ENO2/Phosphopyruvate hydratase "]
[null,2012,8960.73,8433.02,8277.3,4193.62,3905.35,4327.61,3466.94,4413.19,4181.97,1574.81,2187.98,1802.26,8557.01666666667,4142.19333333333,4020.7,1855.01666666667,-1.04671300886358,{"v":2.12458199351774e-12,"d":"2.12E-12"},{"v":6.7902823574726e-12,"d":"6.79E-12"},-1.08966120546227,{"v":1.57154918583468e-10,"d":"1.57E-10"},{"v":1.16905323266914e-09,"d":"1.17E-09"},-1.15896274268037,{"v":2.51716101216238e-06,"d":"2.52E-06"},{"v":2.39e-05,"d":"2.39E-05"},"CDC19/Pyruvate kinase "]
[null,"0020",336.03,320.64,341.61,805.72,819.1,851.2,893.71,885.07,929.18,563.49,1041.17,698.16,332.76,825.34,902.653333333333,767.606666666667,1.31050653989342,{"v":3.08069665126254e-34,"d":"3.08E-34"},{"v":3.02039831823071e-33,"d":"3.02E-33"},1.43969000059177,{"v":1.14905290967675e-29,"d":"1.15E-29"},{"v":2.91252994466676e-28,"d":"2.91E-28"},-0.10462132070527,0.0930218831869224,0.210321878,"pyruvate dehydrogenase"]
["TCA cycle",2286,908.63,1541.12,1291.17,27.98,21.61,35.04,12.97,19.42,41.05,0.47,6.6,10.54,1246.97333333333,28.21,24.48,5.87,-5.46608013715104,{"v":1.64865161905979e-196,"d":"1.65E-196"},{"v":3.49387323885363e-194,"d":"3.49E-194"},-5.67068324504396,{"v":1.18407971096367e-18,"d":"1.18E-18"},{"v":1.67083412822838e-17,"d":"1.67E-17"},-2.26477425747552,0.0762630580360602,0.181213287,"PCK1/Phosphoenolpyruvate carboxykinase "]
[null,1939,33.51,33.27,42.46,142.68,154.36,153.8,204.61,218.15,202.1,448.64,1130.05,738.62,36.4133333333333,150.28,208.286666666667,772.436666666667,2.04511430259764,{"v":3.0280590623182e-52,"d":"3.03E-52"},{"v":5.95878765477617e-51,"d":"5.96E-51"},2.51603177066999,{"v":2.8520993653976e-51,"d":"2.85E-51"},{"v":1.60981897170638e-49,"d":"1.61E-49"},2.36176362787079,{"v":1.18809513352134e-18,"d":"1.19E-18"},{"v":1.3e-16,"d":"1.30E-16"},"CIT2/Citrate (Si)-synthase "]
[null,2968,2.94,3.14,3.11,17.24,15.79,17.29,36.72,19.53,12.46,27.04,11.82,10.34,3.06333333333333,16.7733333333333,22.9033333333333,16.4,2.45299515559025,{"v":1.32509612608362e-47,"d":"1.33E-47"},{"v":2.19257647288911e-46,"d":"2.19E-46"},2.90238331641227,{"v":3.49191472965063e-08,"d":"3.49E-08"},{"v":1.99355924346582e-07,"d":"1.99E-07"},-0.0324736066526844,0.37430828977072,0.558316939,"CIT3/Dual specificity mitochondrial citrate and methylcitrate synthase"]
[null,2657,1510.09,1985.52,2436.92,272.63,218.95,341.9,289.09,258.47,182.72,93.69,173.05,100.28,1977.51,277.826666666667,243.426666666667,122.34,-2.83142800479936,{"v":2.94338534424529e-62,"d":"2.94E-62"},{"v":7.7971409840344e-61,"d":"7.80E-61"},-3.02212586546137,{"v":1.9147609286375e-48,"d":"1.91E-48"},{"v":1.01779767808644e-46,"d":"1.02E-46"},-1.18328889912947,0.0114445080258059,0.038786142,"ACO1/Aconitate hydratase "]
[null,2547,366.11,446.87,500.32,95.72,85.36,98.99,94.03,64.38,19.93,125.79,119.93,97.2,437.766666666667,93.3566666666667,59.4466666666667,114.306666666667,-2.22933715090401,{"v":6.33473559608684e-54,"d":"6.33E-54"},{"v":1.31714691073353e-52,"d":"1.32E-52"},-2.88049428444831,{"v":1.96656251066362e-10,"d":"1.97E-10"},{"v":1.44328816968945e-09,"d":"1.44E-09"},0.2920845926583,{"v":1.01354016161274e-06,"d":"1.01E-06"},{"v":1.04e-05,"d":"1.04E-05"},"IDP2/Isocitrate dehydrogenase (NADP(+)) "]
[null,4934,35.79,43.28,37.88,11.45,12.85,14.09,23.16,26.09,27.82,10.76,4.37,0,38.9833333333333,12.7966666666667,25.69,5.04333333333333,-1.60708939639284,{"v":1.12295816051638e-17,"d":"1.12E-17"},{"v":4.91071386067084e-17,"d":"4.91E-17"},-0.601650565617815,0.156070154807651,0.247716920272757,-1.34331857263022,0.548624369219636,0.710099379,"IDP3/Peroxisomal NADP-dependent isocitrate dehydrogenase"]
[null,1336,700.32,936.25,1267.65,195,158.29,213.6,239.58,225.06,225.85,133.66,165.64,112.97,968.073333333333,188.963333333333,230.163333333333,137.423333333333,-2.35701001907256,{"v":4.04289854302625e-36,"d":"4.04E-36"},{"v":4.26750401763882e-35,"d":"4.27E-35"},-2.07245831831167,{"v":3.97831409576086e-18,"d":"3.98E-18"},{"v":5.33854648879674e-17,"d":"5.34E-17"},-0.459479336853138,0.76893770321121,0.865610507,"IDH2/Isocitrate dehydrogenase (NAD(+)) "]
[null,4959,722.43,901.24,1425.7,429.36,412.25,464.13,436.46,366.97,364.91,387.47,596.39,498.26,1016.45666666667,435.246666666667,389.446666666667,494.04,-1.22364355770746,{"v":1.54691306642221e-07,"d":"1.55E-07"},{"v":3.46201908854036e-07,"d":"3.46E-07"},-1.38405103688817,{"v":8.79633767126909e-07,"d":"8.80E-07"},{"v":4.24316729076637e-06,"d":"4.24E-06"},0.182794605443444,0.000271970321274333,0.001581081,"IDH1/Isocitrate dehydrogenase (NAD(+)) "]
[null,"0728",115.14,122.56,110.99,40.94,36.37,47.55,41.85,35.68,39.3,61.11,57.32,46.34,116.23,41.62,38.9433333333333,54.9233333333333,-1.48163361908288,{"v":1.06458738650682e-26,"d":"1.06E-26"},{"v":7.1797753973716e-26,"d":"7.18E-26"},-1.57753420811917,{"v":1.96973117544978e-11,"d":"1.97E-11"},{"v":1.60241874971583e-10,"d":"1.60E-10"},0.400142221182641,{"v":6.75357946328176e-07,"d":"6.75E-07"},{"v":7.23e-06,"d":"7.23E-06"},"SDH1/Succinate dehydrogenase "]
[null,1069,12.33,15.71,16.41,3.6,3.12,4.67,0,0,0,5.38,9.18,14.43,14.8166666666667,3.79666666666667,0.001,9.66333333333333,-1.96441567200902,{"v":2.93815012679139e-17,"d":"2.94E-17"},{"v":1.25303461289633e-16,"d":"1.25E-16"},-13.8549332978833,{"v":3.33212630800269e-11,"d":"3.33E-11"},{"v":2.63632825669288e-10,"d":"2.64E-10"},1.34778758635328,0.00301684991796245,0.012677548,"YJL045W-like protein（succinate dehydrogenase）"]
[null,"0983",229.04,236.03,217.92,812.6,859.28,819.89,1404.37,952.28,1144.47,1653.8,1386.22,1741.81,227.663333333333,830.59,1167.04,1593.94333333333,1.86723454762096,{"v":4.0774355959263e-49,"d":"4.08E-49"},{"v":7.17784988292457e-48,"d":"7.18E-48"},2.35788015006131,{"v":2.76240660408378e-31,"d":"2.76E-31"},{"v":7.71641640681566e-30,"d":"7.72E-30"},0.940391933179234,{"v":4.00950585351109e-15,"d":"4.01E-15"},{"v":2.67e-13,"d":"2.67E-13"},"SDH3/Succinate dehydrogenase cytochrome b subunit "]
[null,3772,256.88,278.66,259.62,890.64,1064.05,925.1,851.35,758.3,1113.39,1404.12,1805.67,1779.18,265.053333333333,959.93,907.68,1662.99,1.85664652130423,{"v":1.90504190075753e-39,"d":"1.91E-39"},{"v":2.26712329874168e-38,"d":"2.27E-38"},1.77590108494078,{"v":3.46426601706651e-15,"d":"3.46E-15"},{"v":3.85505212265024e-14,"d":"3.86E-14"},0.792778382745733,{"v":3.20982940137325e-10,"d":"3.21E-10"},{"v":7.5e-09,"d":"7.50E-09"},"SDH4/Succinate dehydrogenase membrane anchor subunit "]
[null,1419,882.79,1269.56,1195.96,165.51,131.77,187.18,186.01,140.57,161.9,84.56,89.83,3.54,1116.10333333333,161.486666666667,162.826666666667,59.31,-2.78898364669212,{"v":6.29825140731383e-74,"d":"6.30E-74"},{"v":2.44389896157037e-72,"d":"2.44E-72"},-2.77706170480843,{"v":1.39508663366009e-35,"d":"1.40E-35"},{"v":4.74416106788135e-34,"d":"4.74E-34"},-1.44506777515157,0.274633664238946,0.45498775,"MDH2/Cytoplasmic malate dehydrogenase"]
[null,"0935",326.33,449.65,555.28,169.2,133.4,186.31,174.3,180.82,95.43,56.72,107.14,56.87,443.753333333333,162.97,150.183333333333,73.5766666666667,-1.44515154328609,{"v":2.97915784290248e-14,"d":"2.98E-14"},{"v":1.07923469522634e-13,"d":"1.08E-13"},-1.56303323864111,{"v":1.11131393970338e-07,"d":"1.11E-07"},{"v":6.02904959660248e-07,"d":"6.03E-07"},-1.1472861905901,0.0437739750291707,0.115692354,"MDH1/Malate dehydrogenase "]
["Pentose phosphate pathway",2090,259.39,381.4,380.79,144,165.95,130.26,260.73,156.06,136.63,272.28,156.64,200.36,340.526666666667,146.736666666667,184.473333333333,209.76,-1.21453836244639,{"v":2.38755400210711e-07,"d":"2.39E-07"},{"v":5.26216902064407e-07,"d":"5.26E-07"},-0.884355498602399,0.0161209202781649,0.035221450420008,0.515510172909687,0.00183363743110126,0.008304672,"SOL4/6-Phosphogluconolactonase"]
[null,1762,53.33,44.74,49.54,263.62,290.56,281.78,250.94,213.93,319.92,228.43,332.4,300.23,49.2033333333333,278.653333333333,261.596666666667,287.02,2.50164345053003,{"v":3.48737754815232e-70,"d":"3.49E-70"},{"v":1.22391403123053e-68,"d":"1.22E-68"},2.41051619682188,{"v":2.34969221599382e-18,"d":"2.35E-18"},{"v":3.24044455480256e-17,"d":"3.24E-17"},0.0426798581752112,0.0156547951817657,0.050303829,"SOL3/6-Phosphogluconolactonase"]
[null,1781,150.08,117.73,135.28,706.13,729.93,718.75,614.12,581.57,574.72,750.05,753,754.33,134.363333333333,718.27,590.136666666667,752.46,2.41838676768185,{"v":5.21940881470701e-69,"d":"5.22E-69"},{"v":1.73246641982142e-67,"d":"1.73E-67"},2.13490960735222,{"v":1.28860098104175e-42,"d":"1.29E-42"},{"v":6.02999177025946e-41,"d":"6.03E-41"},0.0670886320233119,{"v":1.02256828679934e-05,"d":"1.02E-05"},{"v":8.42e-05,"d":"8.42E-05"},"GND1/6-Phosphogluconate dehydrogenase"]
[null,2082,194.54,211.76,185.3,100.1,91.29,109.75,69.05,101.64,112.04,80.36,145.7,92.93,197.2,100.38,94.2433333333333,106.33,-0.974187700505765,{"v":1.79509645250957e-10,"d":"1.80E-10"},{"v":5.0387068025103e-10,"d":"5.04E-10"},-1.06519707922574,0.000620512885102673,0.00189687774759192,0.0830768458001786,0.0282520235593672,0.081426155,"GND2/6-Phosphogluconate dehydrogenase"]
["Ehrlich pathway",1736,5.95,6.78,9.76,2637.86,2554.69,2749.8,2694.19,3216.72,2555.61,1546.43,2153.16,1673.01,7.49666666666667,2647.45,2822.17333333333,1790.86666666667,8.46413846697521,0,0,8.55634162803854,0,0,-0.563945507585174,0.671263995297262,0.800808283,"ARO9/Aromatic amino acid aminotransferase II"]
[null,3966,7.57,10.25,12.36,2124.04,1763.28,2321.98,2150.92,2734.41,1843.49,868.85,974.56,877.11,10.06,2069.76666666667,2242.94,906.84,7.68469402056026,0,0,7.80061691260775,0,0,-1.19054820218924,{"v":3.3080312353803e-19,"d":"3.31E-19"},{"v":3.92e-17,"d":"3.92E-17"},"ARO10/Phenylpyruvate decarboxylase "]
[null,2431,16070.47,14536.59,14586.39,8834.61,9555.21,8971.96,6405.92,6258.97,7606.19,4698.46,8829.54,6794.45,15064.4833333333,9120.59333333333,6757.02666666667,6774.15,-0.723951607665818,0.000479817239258507,0.000781955926741903,-1.15669073980859,{"v":1.53249574221346e-08,"d":"1.53E-08"},{"v":9.10023230869704e-08,"d":"9.10E-08"},-0.429087748101442,0.77948235507624,0.871947478,"PDC1/Pyruvate decarboxylase isozyme I "]
[null,2517,24.2,23.52,27.52,726.81,635.11,910,981.35,1641.21,1075.89,70.61,248.73,126.64,25.08,757.306666666667,1232.81666666667,148.66,4.91626837574068,0,0,5.6192771127815,{"v":7.65703776319877e-220,"d":"7.66E-220"},{"v":3.81111652304666e-217,"d":"3.81E-217"},-2.34886111586433,{"v":5.44802735706735e-06,"d":"5.45E-06"},{"v":4.78e-05,"d":"4.78E-05"},"PDC5/Pyruvate decarboxylase isozyme II"]
[null,5285,1879.07,2368.82,2824.29,89.2,70.12,113.92,41.29,90.92,98.4,95.9,254.29,58.29,2357.39333333333,91.08,76.87,136.16,-4.69391439202028,{"v":4.33668126876595e-192,"d":"4.34E-192"},{"v":8.53396921103585e-190,"d":"8.53E-190"},-4.93862801503101,{"v":4.79342057031354e-52,"d":"4.79E-52"},{"v":2.76252396025964e-50,"d":"2.76E-50"},0.58009674554934,0.0342519965046358,0.094331382,"PDC6/Pyruvate decarboxylase isozyme III"]
[null,3300,113.38,113.18,104.69,277.89,256.78,243.21,271.13,182.11,270.87,436.43,338.35,370.73,110.416666666667,259.293333333333,241.37,381.836666666667,1.2316271598286,{"v":2.04478435380522e-23,"d":"2.04E-23"},{"v":1.18224153089892e-22,"d":"1.18E-22"},1.12828842009341,{"v":1.87580700154108e-06,"d":"1.88E-06"},{"v":8.63028851549361e-06,"d":"8.63E-06"},0.558370533540104,{"v":4.6373475436622e-08,"d":"4.64E-08"},{"v":6.5e-07,"d":"6.50E-07"},"ADH2/NADH-alcohol dehydrogenase isozyme II"]
[null,4345,61.02,66.07,80.67,288.36,291.21,243.37,252.3,245.41,199.49,298,228.11,260.3,69.2533333333333,274.313333333333,232.4,262.136666666667,1.98586932943051,{"v":3.13174002507031e-40,"d":"3.13E-40"},{"v":3.85176061119139e-39,"d":"3.85E-39"},1.74665465033464,{"v":4.17850516569321e-26,"d":"4.18E-26"},{"v":8.79896760852706e-25,"d":"8.80E-25"},-0.0655055814350413,0.0587509258279667,0.147093112,"ADH5/NADH-alcohol dehydrogenase isoenzyme V"]
[null,"0332",518.74,647.38,725.89,210.93,191.96,216.83,301.04,223.67,154.45,197.6,180.11,154.44,630.67,206.573333333333,226.386666666667,177.383333333333,-1.61023128014513,{"v":1.85956037232588e-25,"d":"1.86E-25"},{"v":1.19280298620671e-24,"d":"1.19E-24"},-1.47809631676587,{"v":3.24936124324619e-08,"d":"3.25E-08"},{"v":1.85896058586968e-07,"d":"1.86E-07"},-0.219783565328754,0.0484290504719679,0.125455398,"SFA1/S-(hydroxymethyl)glutathione dehydrogenase"]
["Tryptophan metabolism",3148,39.31,35.73,38.98,14.53,9.82,15.21,8.71,15.97,7.56,0.05,4.73,3.73,38.0066666666667,13.1866666666667,10.7466666666667,2.83666666666667,-1.52717257537395,{"v":3.27409607475476e-21,"d":"3.27E-21"},{"v":1.72469114454098e-20,"d":"1.72E-20"},-1.82236325760509,{"v":1.38296662795925e-07,"d":"1.38E-07"},{"v":7.43056161734729e-07,"d":"7.43E-07"},-2.21681138907315,0.147531782457497,0.298290994,"DDC1"]
[null,4515,569.19,727.53,865,299.59,301.55,233.36,212.01,201.2,271.62,312.34,156.77,343.82,720.573333333333,278.166666666667,228.276666666667,270.9766667,-1.37319571325099,{"v":9.35686780254822e-10,"d":"9.36E-10"},{"v":2.4954666791888e-09,"d":"2.50E-09"},-1.65836186030655,{"v":1.74954645729264e-09,"d":"1.75E-09"},{"v":1.16388418635203e-08,"d":"1.16E-08"},-0.03778092,0.216018831,0.388559143,"NIT1/Nitrilase "]
[null,3024,549.4,658.76,456.18,81.91,86.49,101.29,85.63,81.55,73.61,156.07,110.35,152.23,554.78,89.8966666666667,80.2633333333333,139.55,-2.6255762516973,{"v":3.01569443850343e-51,"d":"3.02E-51"},{"v":5.80995676788598e-50,"d":"5.81E-50"},-2.78910280142443,{"v":5.02510958231823e-41,"d":"5.03E-41"},{"v":2.21874798090261e-39,"d":"2.22E-39"},0.634442597,{"v":1.15e-06,"d":"1.15E-06"},{"v":1.18e-05,"d":"1.18E-05"},"ALD6/Aldehyde dehydrogenase (NADP(+)) "]
[null,1569,700.61,606.74,393.52,114.29,115.01,121.98,190.08,131.87,162.43,160.68,303.25,207.69,566.956666666667,117.093333333333,161.46,223.8733333,-2.2755795332178,{"v":1.80311535324373e-25,"d":"1.80E-25"},{"v":1.15794470820198e-24,"d":"1.16E-24"},-1.81206167526161,{"v":7.23009461069463e-09,"d":"7.23E-09"},{"v":4.49826909017649e-08,"d":"4.50E-08"},0.935023753,{"v":4.83e-08,"d":"4.83E-08"},{"v":6.74e-07,"d":"6.74E-07"},"ALD4/Aldehyde dehydrogenase (NADP(+)) "]
[null,3487,141.56,187.67,215.6,77.96,86.49,99.89,34.29,69.44,96.01,84.58,137.13,103.05,181.61,88.1133333333333,66.58,108.2533333,-1.04341139422165,{"v":1.85620558972288e-07,"d":"1.86E-07"},{"v":4.13240113105983e-07,"d":"4.13E-07"},-1.44768286841029,0.00172796227394916,0.00478290872086535,0.296979199,0.001076551,0.0052089,"HFD1/Hexadecenal dehydrogenase"]
[null,"0177",25.49,21.49,24.75,144.79,146.57,126.79,103.8,158.43,176.22,48.61,41.86,60.81,23.91,139.383333333333,146.15,50.4266666666667,2.54337202708527,{"v":3.57707846919929e-63,"d":"3.58E-63"},{"v":9.61448895867712e-62,"d":"9.61E-62"},2.61176379398179,{"v":5.20586462442035e-20,"d":"5.21E-20"},{"v":7.91725244963928e-19,"d":"7.92E-19"},-1.46679929456829,0.000792834390494806,0.004010506,"BNA2/Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase"]
[null,"0784",30.51,31.97,36.6,295.74,290.87,250.3,350.57,160.07,330.77,305.03,205.98,218.36,33.0266666666667,278.97,280.47,243.123333333333,3.07840671223884,{"v":3.44470483028841e-89,"d":"3.44E-89"},{"v":1.89803236148891e-87,"d":"1.90E-87"},3.08614319067159,{"v":2.51651423836791e-16,"d":"2.52E-16"},{"v":3.06175899001429e-15,"d":"3.06E-15"},-0.198421625089972,0.2740935661068,0.454433632,"BNA1/3-Hydroxyanthranilic acid dioxygenase"]
[null,2995,88.17,91.91,108.99,436.77,542.21,407.4,320.47,363.44,444,1073.5,959.54,1174.37,96.3566666666667,462.126666666667,375.97,1069.13666666667,2.26183195012582,{"v":2.85936862287846e-43,"d":"2.86E-43"},{"v":3.98863825621779e-42,"d":"3.99E-42"},1.96416115726658,{"v":6.89036064043585e-21,"d":"6.89E-21"},{"v":1.10629690634564e-19,"d":"1.11E-19"},1.21008603646943,{"v":2.08106292048665e-13,"d":"2.08E-13"},{"v":1.04e-11,"d":"1.04E-11"},"ERG10/Acetyl-CoA C-acetyltransferase "]
["Shikimate pathway as well as  tryptophan, phenylalanine, and tyrosine\n biosynthesis","0519",412.89,350.03,410.52,532.37,410.16,556.07,342.1,372.69,332.32,51.08,88.4,88.45,391.146666666667,499.533333333333,349.036666666667,75.97666667,0.352871280309701,{"v":9.44901216532867e-06,"d":"9.45E-06"},{"v":1.82552794638713e-05,"d":"1.83E-05"},-0.164331069422951,0.935759558796183,0.957802128324753,-2.716952628,{"v":2.46e-16,"d":"2.46E-16"},{"v":2.06e-14,"d":"2.06E-14"},"ARO3/3-deoxy-7-phosphoheptulonate synthase"]
[null,4441,774.57,672.67,731.22,965.38,859.95,912.68,648.46,708.09,773.43,460.66,412.13,446.53,726.153333333333,912.67,709.993333333333,439.7733333,0.329819092428268,{"v":3.12022915906945e-05,"d":"3.12E-05"},{"v":5.72128541313567e-05,"d":"5.72E-05"},-0.0324687393591848,0.450111054167226,0.569004391956952,-1.053333184,{"v":4.57e-05,"d":"4.57E-05"},0.000321923,"ARO4/3-deoxy-7-phosphoheptulonate synthase"]
[null,3726,140.52,160.1,155.45,87.11,71.32,90.78,87.34,82.5,54.45,46.52,24.17,29.59,152.023333333333,83.07,74.7633333333333,33.42666667,-0.871893313477443,5.67736520401239e-10,1.53948239537934e-09,-1.02388997463279,2.84664755579384e-07,1.47170872218803e-06,-1.313328059,0.006022724,0.022525317,"ARO1/Pentafunctional AROM polypeptide"]
[null,5490,133.03,117.44,142.17,411.96,353.43,422.09,347.15,455.53,292.89,75.26,153.07,145.69,130.88,395.826666666667,365.19,124.6733333,1.59662415599114,{"v":2.15719602647782e-50,"d":"2.16E-50"},{"v":4.02920342572637e-49,"d":"4.03E-49"},1.4804026071436,{"v":2.1935346953795e-21,"d":"2.19E-21"},{"v":3.68392713411127e-20,"d":"3.68E-20"},-1.666715893,0.000172149,0.001057124,"ARO2/Bifunctional chorismate synthase/riboflavin reductase [NAD(P)H] "]
[null,1047,48.34,47.29,56.91,212.22,175.28,216.03,170.94,158.15,156.64,41.65,80.39,129.14,50.8466666666667,201.176666666667,161.91,83.72666667,1.98423788073376,{"v":1.35390280342428e-75,"d":"1.35E-75"},{"v":5.48529738740277e-74,"d":"5.49E-74"},1.67096698899508,{"v":7.93222978485853e-24,"d":"7.93E-24"},{"v":1.49755027834829e-22,"d":"1.50E-22"},-1.26470389,0.088230732,0.20223715,"TRP3/Bifunctional anthranilate synthase/indole-3-glycerol-phosphate synthase "]
[null,5383,219.4,194.37,218.96,309.74,283.6,324.39,188,203.42,246.94,142.13,113.14,121.76,210.91,305.91,212.786666666667,125.6766667,0.536479768331917,{"v":4.02951566037664e-10,"d":"4.03E-10"},{"v":1.10296230942252e-09,"d":"1.10E-09"},0.0127802534783422,0.380192357693724,0.497860119199507,-1.283390447,{"v":2.33e-07,"d":"2.33E-07"},{"v":2.84e-06,"d":"2.84E-06"},"TRP5/Tryptophan synthase"]
[null,2918,13.7,18.89,16.66,63.81,43.24,74.34,65.04,79.24,40.85,22.08,51.76,26.53,16.4166666666667,60.4633333333333,61.71,33.45666667,1.88089929284366,{"v":1.87391771576984e-31,"d":"1.87E-31"},{"v":1.59340842806973e-30,"d":"1.59E-30"},1.91034307073614,{"v":5.65294684080717e-08,"d":"5.65E-08"},{"v":3.17109466735853e-07,"d":"3.17E-07"},-0.853766802,0.464487856,0.640417769,"ARO7/Chorismate mutase"]
[null,4366,26.66,29.29,30.14,46.44,33.63,41.74,11.56,49.06,55.9,10.23,7.37,6.61,28.6966666666667,40.6033333333333,38.84,8.07,0.500715003647031,{"v":5.42383399070961e-07,"d":"5.42E-07"},{"v":1.16602907876746e-06,"d":"1.17E-06"},0.436660033987102,0.304121163173809,0.422604915831626,-2.330957592,{"v":2.52e-07,"d":"2.52E-07"},{"v":3.04e-06,"d":"3.04E-06"},"TYR1/Prephenate dehydrogenase"]
[null,"0955",14.16,17.85,21.52,84.71,72.09,94.04,61.39,93.17,62.44,24.88,28.04,18.18,17.8433333333333,83.6133333333333,72.3333333333333,23.7,2.22834786693034,{"v":3.65831428687506e-59,"d":"3.66E-59"},{"v":8.99879987530427e-58,"d":"9.00E-58"},2.01927548490421,{"v":9.57774045864422e-14,"d":"9.58E-14"},{"v":9.58649524882579e-13,"d":"9.59E-13"},-1.81884596,{"v":5.08e-08,"d":"5.08E-08"},{"v":7.05e-07,"d":"7.05E-07"},"AAT1/Aspartate transaminase "]
[null,4561,76.15,88.21,136.24,592.56,436.58,589.99,580.25,357.87,432.03,148.75,77.69,163.75,100.2,539.71,456.716666666667,130.0633333,2.42930190995541,{"v":1.50315737431215e-49,"d":"1.50E-49"},{"v":2.68908997807141e-48,"d":"2.69E-48"},2.18841692948316,{"v":3.42621533107947e-16,"d":"3.43E-16"},{"v":4.12275361267255e-15,"d":"4.12E-15"},-2.052970115,{"v":3.93e-06,"d":"3.93E-06"},{"v":3.53e-05,"d":"3.53E-05"},"HIS5/Histidinol-phosphate aminotransferase"]
[null,1736,5.95,6.78,9.76,2637.86,2554.69,2749.8,2694.19,3216.72,2555.61,1546.43,2153.16,1673.01,7.49666666666667,2647.45,2822.17333333333,1790.86666666667,8.46413846697521,0,0,8.55634162803854,0,0,-0.563945507585174,0.671263995297262,0.800808283,"ARO9/Aromatic amino acid aminotransferase II"]
["Arginine and proline biosynthesis","0955",14.16,17.85,21.52,84.71,72.09,94.04,61.39,93.17,62.44,24.88,28.04,18.18,17.8433333333333,83.6133333333333,72.3333333333333,23.7,2.22834786693034,{"v":3.65831428687506e-59,"d":"3.66E-59"},{"v":8.99879987530427e-58,"d":"9.00E-58"},2.01927548490421,{"v":9.57774045864422e-14,"d":"9.58E-14"},{"v":9.58649524882579e-13,"d":"9.59E-13"},-1.81884595973855,{"v":5.083042422903e-08,"d":"5.08E-08"},{"v":7.05288303615523e-07,"d":"7.05E-07"},"AAT1/Aspartate aminotransferase, mitochondrial"]
[null,1570,503.9,475.15,584.16,1350.95,1156.61,1303.41,1251.34,1211.18,1004.81,773.31,747.04,539,521.07,1270.32333333333,1155.77666666667,686.45,1.28564664977966,{"v":1.43674796107557e-34,"d":"1.44E-34"},{"v":1.42639302081556e-33,"d":"1.43E-33"},1.14931354876921,{"v":4.19880405169275e-27,"d":"4.20E-27"},{"v":9.23231011366177e-26,"d":"9.23E-26"},-0.887969205016915,0.0124389659773442,0.0416133015180725,"GDH1/NADP(+)-dependent glutamate dehydrogenase"]
[null,"0289",51.52,70.59,75.3,40.17,24.74,46.21,26.14,40.44,12.3,5.41,15.9,3.58,65.8033333333333,37.04,26.2933333333333,8.29666666666667,-0.829076568366404,0.000403996823932995,0.000662703929702532,-1.32346361596989,0.00668223853090477,0.0160391301870687,-2.15848036900036,0.0156987466371994,0.0504153506552701,"GDH2/NAD(+)-dependent glutamate dehydrogenase"]
[null,"0329",443.47,632.31,686.25,156.5,127.28,145.42,64.41,110.33,75.74,95.94,54.46,80.11,587.343333333333,143.066666666667,83.4933333333333,76.8366666666667,-2.03751650632184,{"v":1.04257847992287e-32,"d":"1.04E-32"},{"v":9.46393315383032e-32,"d":"9.46E-32"},-2.81447116882706,{"v":4.14672409166335e-36,"d":"4.15E-36"},{"v":1.45534066678569e-34,"d":"1.46E-34"},-0.896820736990935,0.129704520693934,0.270910908630347,"GLT1/NAD(+)-dependent glutamate synthase"]
[null,2937,544.24,519.11,560.79,1153.92,881.86,1316.42,1351.59,1609.64,1200.03,339.85,555.03,375.78,541.38,1117.4,1387.08666666667,423.553333333333,1.04543222870098,{"v":1.17596035234359e-26,"d":"1.18E-26"},{"v":7.91152813359365e-26,"d":"7.91E-26"},1.35734443491179,{"v":5.73843364179042e-51,"d":"5.74E-51"},{"v":3.17352769583864e-49,"d":"3.17E-49"},-1.39953017684786,{"v":2.07884821204761e-05,"d":"2.08E-05"},0.000158102640171487,"GLN1/Glutamine synthetase"]
[null,4714,430.95,521.34,524.7,280.23,190.81,270.94,187.2,205.37,122.79,119.84,153.17,120.72,492.33,247.326666666667,171.786666666667,131.243333333333,-0.993207853554854,{"v":9.54963767324661e-10,"d":"9.55E-10"},{"v":2.54564603674837e-09,"d":"2.55E-09"},-1.51900758738469,{"v":2.22658411951328e-16,"d":"2.23E-16"},{"v":2.71504411009693e-15,"d":"2.72E-15"},-0.91417365777254,0.0169228291060222,0.053713729403457,"ARG5,6/Acetylglutamate kinase"]
[null,1642,215.89,432.72,670.83,1344.15,1075.52,1304.02,1161.25,1215.48,1031.39,791.14,1019.54,735.61,439.813333333333,1241.23,1136.04,848.763333333333,1.49680722516988,{"v":2.56799264776048e-05,"d":"2.57E-05"},{"v":4.74183628993305e-05,"d":"4.74E-05"},1.36905038651448,{"v":2.30409754970802e-06,"d":"2.30E-06"},{"v":1.04341886556257e-05,"d":"1.04E-05"},-0.548336233593212,0.772297223669259,0.868189822127545,"ARG1/Arginosuccinate synthetase"]
[null,2185,438.77,672.27,976.24,2124.99,1848.33,2048,1810.4,1762.99,1653.53,1137.52,942.19,1095.69,695.76,2007.10666666667,1742.30666666667,1058.46666666667,1.52845564568903,{"v":1.63959291068345e-17,"d":"1.64E-17"},{"v":7.12472944626641e-17,"d":"7.12E-17"},1.32433693340319,{"v":1.77816400985672e-09,"d":"1.78E-09"},{"v":1.18148640218028e-08,"d":"1.18E-08"},-0.923141453463865,0.00302256257510102,0.0126882476689961,"ARG4/Argininosuccinate lyase"]
[null,3070,56.71,71.26,100.63,598.64,509.35,518.28,487.09,451.91,635.76,254.52,184.07,279.48,76.2,542.09,524.92,239.356666666667,2.83066949076745,{"v":1.11981691635536e-64,"d":"1.12E-64"},{"v":3.11901651343105e-63,"d":"3.12E-63"},2.78423466395184,{"v":1.82988963434023e-25,"d":"1.83E-25"},{"v":3.72440362379656e-24,"d":"3.72E-24"},-1.17937040440753,0.00597603291250896,0.0223813924944446,"CAR1/Arginase"]
[null,4762,124.2,115.2,132.4,367.92,472.38,345.94,329.63,303.56,444.48,699.42,620.56,809.01,123.933333333333,395.413333333333,359.223333333333,709.663333333333,1.67379725001231,{"v":9.7801552014992e-25,"d":"9.78E-25"},{"v":6.08224098874273e-24,"d":"6.08E-24"},1.53531679376938,{"v":7.87068833844534e-11,"d":"7.87E-11"},{"v":6.08644331256896e-10,"d":"6.09E-10"},0.843773247994387,{"v":2.87432118978087e-07,"d":"2.87E-07"},{"v":3.40732031475545e-06,"d":"3.41E-06"},"PRO3/Pyrroline-5-carboxylate reductase"]
[null,2524,705.96,857.51,910.67,183.19,179.07,212.06,314.25,272.53,203.19,138.53,249.44,156.76,824.713333333333,191.44,263.323333333333,181.576666666667,-2.10700043015964,{"v":1.24575558182732e-52,"d":"1.25E-52"},{"v":2.4869975564741e-51,"d":"2.49E-51"},-1.64705736650801,{"v":2.01675044205992e-18,"d":"2.02E-18"},{"v":2.7953692836147e-17,"d":"2.80E-17"},-0.0763134795755433,0.0903072416409461,0.205785787157576,"PUT1/Proline dehydrogenase"]
["Serine biosynthesis",4594,233.59,217.04,221.72,88.19,70.15,98.28,76.58,72.12,80.59,27.36,17.39,33.08,224.116666666667,85.54,76.43,25.9433333333333,-1.38957882801301,{"v":7.71591174521649e-24,"d":"7.72E-24"},{"v":4.58626469429804e-23,"d":"4.59E-23"},-1.55203900487328,{"v":8.2150326704894e-13,"d":"8.22E-13"},{"v":7.67530782780366e-12,"d":"7.68E-12"},-1.72123535081219,0.00075841721133533,0.00385428616347768,"SER33/3-phosphoglycerate dehydrogenase"]
[null,4700,107.43,114.01,117.81,115.48,77.64,105.29,50.5,84.45,32.44,28.69,23.16,6.1,113.083333333333,99.47,55.7966666666667,19.3166666666667,-0.185052933172034,0.933611415009926,0.940585120963595,-1.01913547282957,0.00474408998636223,0.0117848877837265,-2.3644153161277,0.000882890297157733,0.00438071045532404,"SER3/3-phosphoglycerate dehydrogenase"]
[null,2126,5.9,5.72,8.39,50.98,44.69,42.82,34.69,34.45,16.51,33.92,30.58,16.85,6.67,46.1633333333333,28.55,27.1166666666667,2.79098873445057,{"v":2.55292925189868e-54,"d":"2.55E-54"},{"v":5.45218611548904e-53,"d":"5.45E-53"},2.09773207906562,{"v":8.67916543886778e-06,"d":"8.68E-06"},{"v":3.64125906343304e-05,"d":"3.64E-05"},-0.767567555796421,0.495086210437749,0.67056758706335,"SER2/Phosphoserine phosphatase"]
["Valine, leucine, and alanine biosynthesis",1947,1547.37,1411.03,1464.47,3825.78,3565.44,3254.94,2776.44,2266.83,3356.84,1651.9,3064.83,2119.93,1474.29,3548.72,2800.03666666667,2278.88666666667,1.26727841034888,{"v":3.11064655875348e-24,"d":"3.11E-24"},{"v":1.89598036932873e-23,"d":"1.90E-23"},0.925425382015841,{"v":5.5436226181482e-07,"d":"5.54E-07"},{"v":2.76172282387274e-06,"d":"2.76E-06"},-0.638969569373614,0.5447171937934,0.706887876667161,"ILV6/Acetolactate synthase small subunit, mitochondrial"]
[null,3489,949.83,1020.15,1111.69,540.16,416.5,557.8,386.45,384.35,400.43,168.43,187.93,110.49,1027.22333333333,504.82,390.41,155.616666666667,-1.02490890532481,{"v":4.26225416982472e-14,"d":"4.26E-14"},{"v":1.52203632376761e-13,"d":"1.52E-13"},-1.39568796688128,{"v":2.74256126188077e-20,"d":"2.74E-20"},{"v":4.21784351370708e-19,"d":"4.22E-19"},-1.6977724858969,{"v":4.88024672596013e-09,"d":"4.88E-09"},{"v":8.4482493322732e-08,"d":"8.45E-08"},"ILV2/Acetolactate synthase catalytic subunit, mitochondrial"]
[null,2703,2285.43,2316.21,2305.29,1135.3,819.87,1225.78,1336.61,1201.55,938.56,158.93,315.63,262.43,2302.31,1060.31666666667,1158.90666666667,245.663333333333,-1.11858690742595,{"v":2.86105017233642e-15,"d":"2.86E-15"},{"v":1.09703454763909e-14,"d":"1.10E-14"},-0.99031771905023,{"v":9.70804771866832e-11,"d":"9.71E-11"},{"v":7.3821612860707e-10,"d":"7.38E-10"},-2.1097407458838,{"v":3.72518481531721e-09,"d":"3.73E-09"},{"v":6.66014190095894e-08,"d":"6.66E-08"},"ILV5/Ketol-acid reductoisomerase, mitochondrial"]
[null,"0778",1466.36,1165.26,1292.35,1675.2,1557.59,1636.95,1104.42,983.29,1257.24,677.01,982.11,556.27,1307.99,1623.24666666667,1114.98333333333,738.463333333333,0.311530735781921,0.000214451822746964,0.000362463050102997,-0.230329365979126,0.757549987802861,0.831711672932728,-1.13628405255827,0.00165852749138057,0.00758720672021665,"ILV3/Dihydroxy-acid dehydratase, mitochondrial"]
[null,"0244",39.31,56.46,61.65,153.24,145.18,157.99,172.17,260.68,192.97,130.49,176.03,162.76,52.4733333333333,152.136666666667,208.606666666667,156.426666666667,1.53571155663997,{"v":7.26398888901863e-28,"d":"7.26E-28"},{"v":5.19799724396008e-27,"d":"5.20E-27"},1.99112892010502,{"v":9.15778014558139e-18,"d":"9.16E-18"},{"v":1.19663117654077e-16,"d":"1.20E-16"},0.0401185746064163,0.00375017265314581,0.0151929357188738,"BAT2/Branched chain amino acid aminotransferase"]
[null,1808,1100.06,1301.46,1730.45,902.19,736.04,863.44,629.28,711.42,727.21,253.55,374.32,222.52,1377.32333333333,833.89,689.303333333333,283.463333333333,-0.723938286176999,0.000738560414711936,0.00117853109906249,-0.998656381860471,{"v":1.31675456829828e-05,"d":"1.32E-05"},{"v":5.36002324270117e-05,"d":"5.36E-05"},-1.55669495645282,{"v":2.79982435489027e-07,"d":"2.80E-07"},{"v":3.34079698188548e-06,"d":"3.34E-06"},"BAT1/Branched chain amino acid aminotransferase"]
[null,1307,84.86,60.49,63.36,90.52,68.65,86.4,95.41,68.32,56.24,28.39,40.14,37.91,69.57,81.8566666666667,73.3233333333333,35.48,0.234634598441147,0.00955665761611693,0.0135539725778132,0.0758070526544219,0.45767913260945,0.576815286670545,-1.20609390950724,0.0032855174461773,0.0135418946591117,"LEU9/2-isopropylmalate synthase 2, mitochondrial"]
[null,5367,560.81,943.56,1347.58,142.09,102.24,158.4,133.07,129.43,125.13,23.03,34.73,26.22,950.65,134.243333333333,129.21,27.9933333333333,-2.82406383881628,{"v":7.79058283355742e-33,"d":"7.79E-33"},{"v":7.09522502692585e-32,"d":"7.10E-32"},-2.87919655362267,{"v":1.67128710411339e-23,"d":"1.67E-23"},{"v":3.10179555763417e-22,"d":"3.10E-22"},-2.26169525165555,{"v":1.82498434790229e-14,"d":"1.82E-14"},{"v":1.1181617583271e-12,"d":"1.12E-12"},"LEU1/3-isopropylmalate dehydratase"]
[null,"0244",39.31,56.46,61.65,153.24,145.18,157.99,172.17,260.68,192.97,130.49,176.03,162.76,52.4733333333333,152.136666666667,208.606666666667,156.426666666667,1.53571155663997,{"v":7.26398888901863e-28,"d":"7.26E-28"},{"v":5.19799724396008e-27,"d":"5.20E-27"},1.99112892010502,{"v":9.15778014558139e-18,"d":"9.16E-18"},{"v":1.19663117654077e-16,"d":"1.20E-16"},0.0401185746064163,0.00375017265314581,0.0151929357188738,"BAT2/Branched chain amino acid aminotransferase"]
[null,1808,1100.06,1301.46,1730.45,902.19,736.04,863.44,629.28,711.42,727.21,253.55,374.32,222.52,1377.32333333333,833.89,689.303333333333,283.463333333333,-0.723938286176999,0.000738560414711936,0.00117853109906249,-0.998656381860471,{"v":1.31675456829828e-05,"d":"1.32E-05"},{"v":5.36002324270117e-05,"d":"5.36E-05"},-1.55669495645282,{"v":2.79982435489027e-07,"d":"2.80E-07"},{"v":3.34079698188548e-06,"d":"3.34E-06"},"BAT1/Branched chain amino acid aminotransferase"]
[null,2477,57.16,63.31,69.91,214.58,215.43,225.54,222.65,292.86,278.61,169.73,185.63,222.65,63.46,218.516666666667,264.706666666667,192.67,1.78382389454922,{"v":3.96887500786737e-54,"d":"3.97E-54"},{"v":8.34675621883558e-53,"d":"8.35E-53"},2.06047510335679,{"v":4.80684140545167e-32,"d":"4.81E-32"},{"v":1.42256522674854e-30,"d":"1.42E-30"},-0.181611369006711,0.0861882095361264,0.198473102449534,"ALT1/Alanine transaminase"]
[null,1903,371.42,368.19,341.01,2534.06,2536.16,2165.79,2158.48,1650.93,2466.02,3426.75,3621.67,3405.4,360.206666666667,2412.00333333333,2091.81,3484.60666666667,2.7433351131606,{"v":1.71806892722703e-80,"d":"1.72E-80"},{"v":7.75947523690241e-79,"d":"7.76E-79"},2.53785502907577,{"v":2.03985336322998e-33,"d":"2.04E-33"},{"v":6.34556657027508e-32,"d":"6.35E-32"},0.530763916610841,{"v":1.05701817188792e-10,"d":"1.06E-10"},{"v":2.78450245956755e-09,"d":"2.78E-09"},"AGX1/Alanine-glyoxylate aminotransferase"]
[" Aspartate and asparagine biosynthesis","0955",14.16,17.85,21.52,84.71,72.09,94.04,61.39,93.17,62.44,24.88,28.04,18.18,17.8433333333333,83.6133333333333,72.3333333333333,23.7,2.22834786693034,{"v":3.65831428687506e-59,"d":"3.66E-59"},{"v":8.99879987530427e-58,"d":"9.00E-58"},2.01927548490421,{"v":9.57774045864422e-14,"d":"9.58E-14"},{"v":9.58649524882579e-13,"d":"9.59E-13"},-1.81884595973855,{"v":5.083042422903e-08,"d":"5.08E-08"},{"v":7.05288303615523e-07,"d":"7.05E-07"},"AAT1/Aspartate aminotransferase, mitochondrial"]
[null,3262,54.8,75.55,120.09,965.32,592.86,965.67,837.97,981.15,696.97,121.29,149.59,91.07,83.48,841.283333333333,838.696666666667,120.65,3.3330892577167,{"v":1.78894667669235e-60,"d":"1.79E-60"},{"v":4.56347045767354e-59,"d":"4.56E-59"},3.32864661658838,{"v":1.70539119800527e-42,"d":"1.71E-42"},{"v":7.91272610938884e-41,"d":"7.91E-41"},-2.80176384777342,{"v":9.56154354522583e-25,"d":"9.56E-25"},{"v":2.74416299747981e-22,"d":"2.74E-22"},"ASN1/Asparagine synthetase"]
[null,5251,226.49,208.06,214.29,259.43,213.32,276.36,203.32,268.09,167.66,79.31,140.64,62.72,216.28,249.703333333333,213.023333333333,94.2233333333333,0.207314818649759,0.000374965143657019,0.000616917868483182,-0.0218887980269687,0.494452121955917,0.609164124146859,-1.40605880402324,0.00297335271964225,0.0125202257762233,"ASN2/Asparagine synthetase"]
[null,3905,54.91,39.73,47.56,230.11,235.76,219.41,240.95,262.13,212.41,171.84,246.16,204.5,47.4,228.426666666667,238.496666666667,207.5,2.26877211738427,{"v":2.77105248721154e-49,"d":"2.77E-49"},{"v":4.92532232404373e-48,"d":"4.93E-48"},2.33101013840101,{"v":1.68291693319269e-33,"d":"1.68E-33"},{"v":5.2651258338457e-32,"d":"5.27E-32"},-0.138619745160876,0.0890372309387795,0.20340176803903,"ASP1/L-asparaginase"]