{"text_format":"3","workbook":"xls","n_sheets":2,"sheets":["Structural Anomalies","Discovered Translocations "],"not_rendered":{"external_links":1,"defined_names":1},"read":"whole","date_system":"1900","formulas":"cached_only"}

{"sheet":"Structural Anomalies","index":0,"n_rows":6,"n_cols":6,"rows_kept":6,"merged":[[0,0,0,5]],"flags":["formulas_cached_only"]}
["Structural Anomalies"]
["Chr","CGH arry [hg19]","Karyotype","Genes","tissue","Laboratory"]
[2,"2q21.2q24.1(133327977_159575936)x1","46,XX,del(2)(q21.2q24.1) after aCGH","more than 20 genes OMIM","CVS fresh",1]
[4,"4p16.3p16.1(71552_8888580)x1,4q31.1q35.2(140096835_191028601)x3","Dir: 46,XX\nafter culture: 46,XX,der(4)(qter->q31.1::p16.1->qter)","more than 20 genes OMIM","CVS cultured",1]
["4; 6","4p16.3p11(3768502_48240465)x2~3,6q27(170861516_170921089)x1","Dir: 46,XY,r(4)(p16.3q12),der(6)(6pter->6q27::4q12->4qter);\nkaryotype after culture: 46,XY,psu idic(4)(q12),der(6)(6pter->6q27::4q12->4qter).","chr 4: more than 20 genes OMIM; chr6:  PSMB1, TBP, PDCD2","CVS fresh",1]
["X (a,b,c,d,e)","Xp22.33p21.1 (61545_37199957)x1,Xp21.1p11.1(37372045_58543823)x1~2, Xq11.1q12(62263093_64986250)x2~3,Xq12q13.3(64986250_75326033)x1~2, Xq13.3q28(75387125_152995703)x1","mos 46,X,r(X)(p21.1q13.3)[24]/45,X[13]","a,b mosaic,d mosaic,e) more than 20 genes OMIM; c) mosaic ARHGEF9, AMER1, ASB12,MTMR8, ZC4H2, ZC3H12B, LAS1L, MSN ","AF cultured",1]

{"sheet":"Discovered Translocations ","index":1,"n_rows":7,"n_cols":7,"rows_kept":7,"merged":[[0,0,0,6]],"flags":["formulas_cached_only"]}
["Discovered Translocations "]
["Chr","CGH arry[hg19]","Karyotype ","genes","tissue","annotations","Laboratory"]
["4;6","4q31.3q35.2(153387189_191028601)x3, 6q27(168300954_170921089)x1","46,XY,der(6)t(4;6)(q31.3;q27)mat","more than 20 genes OMIM","CVS fresh",null,1]
["7;X","7q35q36.3(147416995_159124131)x3mat, Xq26.2q28(131812467_155232907)x1mat","46,XX dir","chr.7: CNTNAP2, MIR548F3, MIR548T, C7orf33, CUL1, EZH2, PDIA4, ZNF786, ZNF425, ZNF398, ZNF282, ZNF212, ZNF783, LOC155060, ZNF777, ZNF746, ZNF767, KRBA1, ZNF467, SSPO, ZNF862, LOC401431, ATP6V0E2, ACTR3C, LRRC61, C7orf29, RARRES2, REPIN1, ZNF775, LOC728743, LOC285972, GIMAP8, GIMAP7, GIMAP4, GIMAP6, GIMAP2, GIMAP1, GIMAP1-GIMAP5, GIMAP5, LOC100128542, TMEM176B, TMEM176A, ABP1, KCNH2, NOS3, ATG9B, ABCB8, ACCN3, CDK5, SLC4A2, FASTK, TMUB1, AGAP3, GBX1, ASB10, ABCF2, CHPF2, MIR671, SMARCD3, NUB1, WDR86, LOC100131176, CRYGN, MIR3907, RHEB, PRKAG2, GALNTL5, GALNT11, MLL3, FABP5P3, LOC100128822, XRCC2, ACTR3B, DPP6, LOC100132707, PAXIP1, LOC202781, HTR5A, INSIG1, EN2, CNPY1, RBM33, SHH, NCRNA00244, C7orf13, RNF32, LMBR1, NOM1, MNX1, UBE3C, DNAJB6, PTPRN2, MIR153-2, MIR595, NCAPG2, ESYT2, WDR60, LOC154822, VIPR2.chr.X: HS6ST2, USP26, TFDP3, GPC4, GPC3, MIR363, MIR92A2, MIR19B2, MIR20B, MIR18B, MIR106A, CCDC160, PHF6, HPRT1, MIR450B, MIR450A1, MIR450A2, MIR542, MGC16121, MIR503, MIR424, PLAC1, FAM122B, FAM122C, MOSPD1, LOC644538, FAM127C, FAM127A, FAM127B, NCRNA00087, LOC100129515, CXorf48, ZNF75D, ZNF449, NCRNA00086, DDX26B, CT45A1, CT45A2, CT45A4, CT45A3, CT45A5, CT45A6, SAGE1, MMGT1, SLC9A6, FHL1, MAP7D3, GPR112, BRS3, HTATSF1, VGLL1, MIR934, CD40LG, ARHGEF6, RBMX, SNORD61, GPR101, ZIC3, LOC158696, FGF13, MIR504, SRD5A1P1, F9, MCF2, ATP11C, MIR505, CXorf66, SOX3, RP1-177G6.2, CDR1, MIR320D2, SPANXB1, SPANXF1, SPANXB2, LDOC1, SPANXC, CXorf18, SPANXA2, SPANXA1, SPANXD, SPANXE, MAGEC3, MAGEC1, MAGEC2, SPANXN4, SPANXN3, SLITRK4, SPANXN2, UBE2NL, SPANXN1, SLITRK2, CXorf1, MIR890, MIR888, MIR892A, MIR892B, MIR891B, MIR891A, CXorf51, MIR506, MIR507, MIR508, MIR514B, MIR509-1, MIR509-2, MIR509-3, MIR510, MIR514-1, MIR514-2, MIR514-3, FMR1-AS1, FMR1, FMR1NB, AFF2, IDS, LOC100131434, CXorf40A, MAGEA9, MAGEA9B, HSFX2, HSFX1, TMEM185A, MAGEA11, MAGEA8, CXorf40B, LOC100272228, MIR2114, MAMLD1, MTM1, MTMR1, CD99L2, HMGB3, MIR4330, GPR50, VMA21, PASD1, PRRG3, FATE1, CNGA2, MAGEA4, GABRE, MIR452, MAGEA5, MAGEA10-MAGEA5, MAGEA10, GABRA3, MIR105-1, MIR767, MIR105-2, GABRQ, MAGEA6, CSAG3, CSAG2, MAGEA2, MAGEA2B, MAGEA12, CSAG1, MAGEA3, CETN2, NSDHL, ZNF185, PNMA5, PNMA3, LOC100287428, PNMA6A, MAGEA1, ZNF275, ZFP92, TREX2, HAUS7, BGN, ATP2B3, FAM58A, DUSP9, PNCK, SLC6A8, BCAP31, ABCD1, PLXNB3, SRPK3, IDH3G, SSR4, PDZD4, L1CAM, AVPR2, ARHGAP4, NAA10, RENBP, HCFC1, TMEM187, MIR3202-1, MIR3202-2, IRAK1, MIR718, MECP2, OPN1LW, OPN1MW2, OPN1MW, TEX28, TKTL1, FLNA, EMD, RPL10, SNORA70, DNASE1L1, TAZ, ATP6AP1, GDI1, FAM50A, PLXNA3, LAGE3, UBL4A, SLC10A3, FAM3A, G6PD, IKBKG, NCRNA00204, NCRNA00204B, CTAG1B, CTAG1A, CTAG2, GAB3, DKC1, SNORA36A, SNORA56, MPP1, LOC100132963, F8, H2AFB1, H2AFB3, F8A1, F8A2, F8A3, MIR1184-1, MIR1184-2, MIR1184-3, FUNDC2, MTCP1NB, MTCP1, BRCC3, VBP1, RAB39B, CLIC2, H2AFB2, TMLHE, SPRY3, VAMP7, IL9R","CVS fresh","Published: Ciaccio C, Redaelli S, Bentivegna A, Marelli S, Crosti F, Sala EM, Cavallari\nU. Unbalanced X;Autosome Translocations May Lead to Mild Phenotypes and Are Associated with Autoimmune Diseases. Cytogenet Genome Res. 2020;160(2):80-84.",2]
["3;4","3q28q29(191261671_197840323)x3pat, 4q34.1q35.2(173123156_190790881)x1pat","46,XX","Duplication chr.3: LINCR-0002, FGF12, FGF12-AS1, FGF12-AS2, MB21D2, PLAAT1, MGC2889, ATP13A5, ATP13A5-AS1, ATP13A4, ATP13A4-AS1, OPA1, OPA1-AS1, LINC02038, LINC02026, DPPA2P3, LINC02028, HES1, LINC02036, LINC02037, LINC00887, CPN2, LRRC15, GP5, ATP13A3, LINC00884, TMEM44-AS1, TMEM44, LSG1, FAM43A, LINC01968, LINC01972, XXYLT1, XXYLT1-AS1, MIR3137, XXYLT1-AS2, ACAP2, PPP1R2, APOD, LOC105374297, SDHAP2, MIR570HG, MIR570, MUC20, MUC4, LINC01983, TNK2, MIR6829, TNK2-AS1, SDHAP1, TFRC, LINC00885, ZDHHC19, SLC51A, PCYT1A, TCTEX1D2, TM4SF19-TCTEX1D2, TM4SF19-AS1, TM4SF19, UBXN7, UBXN7-AS1, RNF168, SMCO1, WDR53, FBXO45, LINC01063, NRROS, CEP19, PIGX, PAK2, SENP5, NCBP2, NCBP2-AS1, NCBP2AS2, PIGZ, MELTF, MELTF-AS1, DLG1, MIR4797, DLG1-AS1, LINC02012, BDH1, LOC220729, RUBCN, MIR922, FYTTD1, LRCH3, IQCG, RPL35A, LMLN, LMLN-AS1, ANKRD18DP. Deletion chr4: GALNTL6, GALNTL6-AS1, LOC101930370, GALNT7, MIR548T, HMGB2, SAP30, SCRG1, HAND2, HAND2-AS1, LINC02269, LINC02268, FBXO8, CEP44, MIR4276, HPGD, GLRA3, LOC101928551, ADAM29, GPM6A, LOC101928590, WDR17, SPATA4, ASB5, SPCS3, VEGFC, LINC02509, NEIL3, AGA, LINC01098, LINC01099, LINC00290, LINC02500, TEMN3-AS1, TENM3-AS1, MIR1305, TENM3, DCTD, FAM92A1P2, WWC2-AS2, WWC2, WWC2-AS1, CLDN22, CLDN24, CDKN2AIP, LOC389247, ING2, RWDD4, TRAPPC11, STOX2, ENPP6, LINC02363, LINC02362, IRF2, LINC02427, LINC02365, CASP3, PRIMPOL, CENPU, ACSL1, SLED1, MIR3945HG, MIR3945, LINC01093, MIR4455, HELT, LINC02436, SLC25A4, CFAP97, SNX25, LRP2BP, ANKRD37, UFSP2, C4orf47, CCDC110, LOC105377590, PDLIM3, SORBS2, TLR3, FAM149A, FLJ38576, CYP4V2, KLKB1, F11, F11-AS1, MTNR1A, FAT1, LINC02374, LOC339975, LINC02514, LINC02492, ZFP42, TRIML2, TRIML1, LINC01060, LINC02508, LINC01262, LOC105379514, FRG1-DT","CVS fresh","father carrier of balanced t(3;4)",2]
["5;17","5p15.33p15.32(22149_4580604)x3mat, 17p13.3(3555_3058821)x1mat","46,XX","Duplication chr5: PLEKHG4B, LRRC14B, CCDC127, SDHA, HRAT5, PDCD6, AHRR, EXOC3-AS1, EXOC3, SLC9A3, PP7080, SLC9A3-AS1, MIR4456, LOC100996325, CEP72, TPPP, ZDHHC11B, ZDHHC11, BRD9, TRIP13, LOC100506688, NKD2, SLC12A7, MIR4635, CTD-3080P12.3, SLC6A19, SLC6A18, TERT, MIR4457, CLPTM1L, LINC01511, SLC6A3, LPCAT1, MIR6075, SDHAP3, LOC728613, MIR4277, MRPL36, NDUFS6, LINC02116, IRX4, CTD-2194D22.4, LOC100506858, LSINCT5, IRX2, C5orf38, LOC105374620, LINC01377, LINC01019, LINC02162, LINC01017, IRX1. Deletion chr17: LINC02091, RPH3AL, LOC100506388, LOC105371430, C17orf97, RFLNB, VPS53, TLCD3A, GEMIN4, DBIL5P, GLOD4, MRM3, NXN, LOC101927727, TIMM22, ABR, MIR3183, BHLHA9, TRARG1, YWHAE, CRK, MYO1C, INPP5K, PITPNA-AS1, PITPNA, SLC43A2, SCARF1, RILP, PRPF8, TLCD2, MIR22HG, MIR22, WDR81, SERPINF2, SERPINF1, SMYD4, RPA1, RTN4RL1, LOC105371485, DPH1, OVCA2, MIR132, MIR212, HIC1, SMG6, LOC101927839, SRR, TSR1, SNORD91B, SNORD91A, SGSM2, MNT, LOC284009, METTL16, PAFAH1B1, CLUH, MIR6776, LOC105371592, CCDC92B, MIR1253, RAP1GAP2, LOC101927911, OR1D5, OR1D2, OR1E3, OR1G1, LOC100288728","CVS fresh","mother carrier balanced 5;17",2]
["16;22","16p13.3p13.13(100293_12012499)x3mat, 22q11.1q11.21(16554425_20311762)x3mat","47,XX,+mar after aCGH"," duplication 16: POLR3K, SNRNP25, RHBDF1, MPG, NPRL3, HBZ, HBM, HBA2, HBA1, HBQ1, LUC7L, FAM234A, RGS11, ARHGDIG, PDIA2, AXIN1, MRPL28, TMEM8A, LOC100134368, NME4, DECR2, RAB11FIP3, LINC00235, CAPN15, MIR5587, MIR3176, PRR35, NHLRC4, PIGQ, RAB40C, WFIKKN1, METTL26, LOC100287175, MCRIP2, LOC105371038, WDR90, RHOT2, RHBDL1, LOC105371184, STUB1, JMJD8, WDR24, FBXL16, METRN, ANTKMT, CCDC78, HAGHL, CIAO3, MSLN, MIR662, RPUSD1, CHTF18, GNG13, PRR25, LMF1, LMF1-AS1, SOX8, SSTR5-AS1, SSTR5, C1QTNF8, CACNA1H, TPSG1, TPSB2, TPSAB1, TPSD1, UBE2I, BAIAP3, TSR3, GNPTG, UNKL, C16orf91, PERCC1, CCDC154, CLCN7, PTX4, TELO2, IFT140, TMEM204, LOC105371046, CRAMP1, JPT2, MAPK8IP3, MIR3177, NME3, MRPS34, EME2, SPSB3, NUBP2, IGFALS, HAGH, FAHD1, MEIOB, LINC00254, LINC02124, HS3ST6, MSRB1, RPL3L, NDUFB10, RPS2, SNORA10, SNORA64, SNHG9, SNORA78, RNF151, TBL3, NOXO1, GFER, SYNGR3, ZNF598, NPW, SLC9A3R2, NTHL1, TSC2, PKD1, MIR1225, LOC105371049, MIR6511B1, MIR6511B2, MIR4516, MIR3180-5, RAB26, SNHG19, SNORD60, TRAF7, CASKIN1, MLST8, BRICD5, PGP, E4F1, DNASE1L2, ECI1, RNPS1, LOC106660606, MIR3677, MIR940, MIR4717, ABCA3, ABCA17P, CCNF, MIR6767, TEDC2, MIR6768, LOC729652, NTN3, TBC1D24, ATP6V0C, AMDHD2, CEMP1, MIR3178, PDPK1, LOC652276, FLJ42627, ERVK13-1, KCTD5, PRSS27, SRRM2-AS1, SRRM2, ELOB, PRSS33, PRSS41, SNORA3C, PRSS21, ZG16B, PRSS30P, PRSS22, FLYWCH2, FLYWCH1, KREMEN2, PAQR4, PKMYT1, LINC00514, LOC101929613, CLDN9, CLDN6, TNFRSF12A, HCFC1R1, THOC6, BICDL2, LOC100128770, MMP25, MMP25-AS1, IL32, ZSCAN10, ZNF205-AS1, ZNF205, ZNF213-AS1, ZNF213, CASP16P, OR1F1, OR1F2P, ZNF200, MEFV, LINC00921, ZNF263, TIGD7, ZNF75A, OR2C1, MTRNR2L4, ZSCAN32, ZNF174, ZNF597, NAA60, MIR6126, C16orf90, CLUAP1, NLRC3, SLX4, DNASE1, TRAP1, CREBBP, LOC102724927, ADCY9, SRL, LINC01569, TFAP4, GLIS2, GLIS2-AS1, PAM16, CORO7-PAM16, CORO7, VASN, DNAJA3, NMRAL1, HMOX2, CDIP1, C16orf96, UBALD1, MGRN1, MIR6769A, NUDT16L1, ANKS3, C16orf71, ZNF500, SEPTIN12, SMIM22, ROGDI, GLYR1, UBN1, PPL, SEC14L5, NAGPA, NAGPA-AS1, C16orf89, ALG1, EEF2KMT, LINC01570, MIR8065, RBFOX1, TMEM114, METTL22, ABAT, TMEM186, PMM2, LOC100130283, CARHSP1, USP7, C16orf72, LINC02177, LINC01177, LINC01195, GRIN2A, ATF7IP2, LINC01290, EMP2, TEKT5, NUBP1, TVP23A, CIITA, DEXI, CLEC16A, SOCS1, TNP2, PRM3, PRM2, PRM1, MIR548H2, LOC105371083, RMI2, LOC400499, LOC101927131, LITAF, SNN, TXNDC11, ZC3H7A, BCAR4, RSL1D1, GSPT1. Deletion chr 22 VCF, TANGO2, MIR185, DGCR8, MIR3618, MIR1306, TRMT2A, MIR6816, RANBP1, SNORA77B, ZDHHC8, CCDC188, LOC284865, LINC00896, RTN4R, MIR1286, DGCR6L","AF fresh","mother carrier of balanced t(16;22)",2]