OUTCOME: Urinary continence at 3 months ANALYSIS: sensitivity_rct_only STUDIES: 3 TREATMENTS: Conventional, Retzius, Ultra Original data: treat1 treat2 TE seTE Dalela_Detroit_RCT_2015_2016 Conventional Retzius -1.0726 0.7036 Ratanapornsompong_2020 Conventional Ultra -1.1059 0.4414 Siltari_2021 Conventional Ultra -0.2000 0.3195 Number of treatment arms (by study): narms Dalela_Detroit_RCT_2015_2016 2 Ratanapornsompong_2020 2 Siltari_2021 2 Results (random effects model): treat1 treat2 OR 95%-CI Dalela_Detroit_RCT_2015_2016 Conventional Retzius 0.3421 [0.0622; 1.8825] Ratanapornsompong_2020 Conventional Ultra 0.5478 [0.2268; 1.3235] Siltari_2021 Conventional Ultra 0.5478 [0.2268; 1.3235] Number of studies: k = 3 Number of pairwise comparisons: m = 3 Number of observations: o = 370 Number of treatments: n = 3 Number of designs: d = 2 Random effects model Treatment estimate (sm = 'OR', comparison: other treatments vs 'Conventional'): OR 95%-CI z p-value Conventional . . . . Retzius 2.9231 [0.5312; 16.0846] 1.23 0.2176 Ultra 1.8254 [0.7556; 4.4099] 1.34 0.1812 Quantifying heterogeneity / inconsistency: tau^2 = 0.2618; tau = 0.5117; I^2 = 63.8% [0.0%; 91.7%] Tests of heterogeneity (within designs) and inconsistency (between designs): Q d.f. p-value Total 2.76 1 0.0964 Within designs 2.76 1 0.0964 Between designs 0.00 0 -- Details of network meta-analysis methods: - Frequentist graph-theoretical approach - Restricted maximum-likelihood estimator for tau^2 - Calculation of I^2 based on Q --- P-SCORE RANKING --- P-score Retzius 0.7879 Ultra 0.6124 Conventional 0.0997 --- SUCRA RANKING --- SUCRA Retzius 0.7895 Ultra 0.6113 Conventional 0.0992 - based on 20000 simulations --- GLOBAL INCONSISTENCY: DESIGN-BY-TREATMENT --- Q statistics to assess homogeneity / consistency Q df p-value Total 2.76 1 0.0964 Within designs 2.76 1 0.0964 Between designs 0.00 0 -- Design-specific decomposition of within-designs Q statistic Design Q df p-value Conventional:Ultra 2.76 1 0.0964 Q statistic to assess consistency under the assumption of a full design-by-treatment interaction random effects model Q df p-value tau.within tau2.within Between designs 0.00 0 -- 0.5117 0.2618 --- LOCAL INCONSISTENCY: NODE SPLITTING/SIDE --- Separate indirect from direct evidence (SIDE) using back-calculation method Random effects model: comparison k prop nma direct indir. RoR z p-value Retzius:Conventional 1 1.00 2.9231 2.9231 . . . . Ultra:Conventional 2 1.00 1.8254 1.8254 . . . . Retzius:Ultra 0 0 1.6014 . 1.6014 . . . Legend: comparison - Treatment comparison k - Number of studies providing direct evidence prop - Direct evidence proportion nma - Estimated treatment effect (OR) in network meta-analysis direct - Estimated treatment effect (OR) derived from direct evidence indir. - Estimated treatment effect (OR) derived from indirect evidence RoR - Ratio of Ratios (direct versus indirect) z - z-value of test for disagreement (direct versus indirect) p-value - p-value of test for disagreement (direct versus indirect)