OUTCOME: Overall complications ANALYSIS: sensitivity_rct_only STUDIES: 2 TREATMENTS: Conventional, Retzius, Ultra Original data: treat1 treat2 TE seTE Dalela_Detroit_RCT_2015_2016 Conventional Retzius -0.5305 0.5225 Ratanapornsompong_2020 Conventional Ultra -0.0880 0.4196 Number of treatment arms (by study): narms Dalela_Detroit_RCT_2015_2016 2 Ratanapornsompong_2020 2 Results (random effects model): treat1 treat2 OR 95%-CI Dalela_Detroit_RCT_2015_2016 Conventional Retzius 0.5883 [0.2113; 1.6384] Ratanapornsompong_2020 Conventional Ultra 0.9158 [0.4023; 2.0843] Number of studies: k = 2 Number of pairwise comparisons: m = 2 Number of observations: o = 212 Number of treatments: n = 3 Number of designs: d = 2 Random effects model Treatment estimate (sm = 'OR', comparison: other treatments vs 'Conventional'): OR 95%-CI z p-value Conventional . . . . Retzius 1.6997 [0.6104; 4.7332] 1.02 0.3100 Ultra 1.0920 [0.4798; 2.4854] 0.21 0.8339 Quantifying heterogeneity / inconsistency: tau^2 = 0; tau = 0 Tests of heterogeneity (within designs) and inconsistency (between designs): Q d.f. p-value Total 0 0 -- Within designs 0 0 -- Between designs 0 0 -- Details of network meta-analysis methods: - Frequentist graph-theoretical approach - Restricted maximum-likelihood estimator for tau^2 --- P-SCORE RANKING --- P-score Conventional 0.7140 Ultra 0.5812 Retzius 0.2048 --- SUCRA RANKING --- SUCRA Conventional 0.7157 Ultra 0.5802 Retzius 0.2041 - based on 20000 simulations --- GLOBAL INCONSISTENCY: DESIGN-BY-TREATMENT --- Q statistics to assess homogeneity / consistency Q df p-value Total 0.00 0 -- Within designs 0.00 0 -- Between designs 0.00 0 -- Q statistic to assess consistency under the assumption of a full design-by-treatment interaction random effects model Q df p-value tau.within tau2.within Between designs 0.00 0 -- 0 0 --- LOCAL INCONSISTENCY: NODE SPLITTING/SIDE --- Separate indirect from direct evidence (SIDE) using back-calculation method Random effects model: comparison k prop nma direct indir. RoR z p-value Retzius:Conventional 1 1.00 1.6997 1.6997 . . . . Ultra:Conventional 1 1.00 1.0920 1.0920 . . . . Retzius:Ultra 0 0 1.5565 . 1.5565 . . . Legend: comparison - Treatment comparison k - Number of studies providing direct evidence prop - Direct evidence proportion nma - Estimated treatment effect (OR) in network meta-analysis direct - Estimated treatment effect (OR) derived from direct evidence indir. - Estimated treatment effect (OR) derived from indirect evidence RoR - Ratio of Ratios (direct versus indirect) z - z-value of test for disagreement (direct versus indirect) p-value - p-value of test for disagreement (direct versus indirect)