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["Table 2. Cox proportional hazard model of OS "]
["Characteristics","Univariate analysis",null,null,"Multivariate analysis"]
[null,"Hazard ratio","95% CI","P-value","Hazard ratio","95% CI","P-value"]
["Age",1.04,"1.02-1.06","<0.001",1.03,"1.01-1.05",0.002]
["Laterality"]
["Bilateral","As reference",null,null,"As reference"]
["Left",{"v":0.4,"d":"0.40"},"0.23-0.73",0.002,{"v":0.9,"d":"0.90"},"0.48-1.67",0.73]
["Right",0.38,"0.21-0.69",0.002,0.81,"0.42-1.56",0.52]
["Grade"]
["I-II","As reference"]
["III or IV",1.79,"0.55-5.9",0.34]
["Unknown",1.69,"0.53-5.37",0.37]
["AJCC stage "]
["IIA","As reference",null,null,"As reference"]
["IIIA",1.45,"0.83-2.54",{"v":0.19,"d":"0.190"},1.73,"0.98-2.05",0.06]
["IIIC",2.88,"1.88-4.4","<0.001",3.26,"2.06-5.15","<0.001"]
["Surgery"]
["No","As reference",null,null,"As reference"]
["BCS",0.64,"0.32-1.29",0.21,0.91,"0.43-1.93",0.81]
["Mastectomy",0.52,"0.32-0.83",0.001,0.58,"0.35-0.96",0.03]
["Radiotherapy"]
["No","As reference",null,null,"As reference"]
["Yes",0.51,"0.34-0.76",0.001,0.54,"0.35-0.83",0.005]
["Chemotherapy"]
["No","As reference",null,null,"As reference"]
["Yes",0.46,"0.31-0.69","<0.001",0.53,"0.33-0.83",0.005]
["ER Status"]
["Negative","As reference",null,null,"As reference"]
["Positive",0.55,"0.36-0.85",0.01,0.53,"0.31-0.91",0.02]
["   Unknown",1.32,"0.77-2.28",0.31,1.23,"0.41-3.7",0.72]
["PR Status"]
["Negative","As reference",null,null,"As reference"]
["Positive",0.61,"0.37-0.98",0.004,0.65,"0.36-1.16",0.15]
["   Unknown",1.24,"0.74-2.08",{"v":0.41,"d":"0.410"},0.75,"0.27-2.1",0.58]
["Marital status"]
["Married","As reference"]
["Single",1.27,"0.85-1.89",0.24]
["Unknown",1.87,"0.67-5.18",0.23]
["Abbreviation: SEER, Surveillance, Surveillance, Epidemiology, and End Results; AJCC, American Joint Committee on Cancer; ER, estrogen receptor; PR,  progesterone receptor; OS, Overall Survival; BCS, breast conserving surgery; SM, simple mastectomy; RM, radical mastectomy\n"]

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