peptide lca domain realm kingdom subkingdom superphylum phylum subphylum superclass class subclass superorder order suborder infraorder superfamily family subfamily tribe subtribe genus subgenus species group species subgroup species subspecies strain varietas forma EC EC - names GO (biological process) GO (cellular component) GO (molecular function) GO (biological process) - names GO (cellular component) - names GO (molecular function) - names InterPro InterPro - names DLKPTMTGSYEVGLEMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR039426 (14.9%) IPR012910 (14.4%) IPR023996 (14.4%)" "TonB-dependent receptor-like (14.9%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" NGNELVGMVASYTYGFPLAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.10 (100%) orotate phosphoribosyltransferase (100%) "GO:0019856 (25%) GO:0044205 (25%)" "GO:0000287 (25%) GO:0004588 (25%)" "pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" "magnesium ion binding (25%) orotate phosphoribosyltransferase activity (25%)" "IPR000836 (25%) IPR004467 (25%) IPR023031 (25%)" "Phosphoribosyltransferase domain (25%) Orotate phosphoribosyl transferase domain (25%) Orotate phosphoribosyltransferase (25%)" TLDGVDLHLPQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (16.7%) GO:0005886 (16.7%) "GO:0005524 (16.7%) GO:0008233 (16.7%) GO:0015421 (16.7%)" proteolysis (16.7%) plasma membrane (16.7%) "ATP binding (16.7%) peptidase activity (16.7%) ABC-type oligopeptide transporter activity (16.7%)" "IPR003439 (12.9%) IPR003593 (12.9%) IPR005074 (12.9%)" "ABC transporter-like, ATP-binding domain (12.9%) AAA+ ATPase domain (12.9%) Peptidase C39, bacteriocin processing (12.9%)" SLLVMNPPYGER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.1.1.173 (71.4%) 2.1.1.- (28.6%)" "23S rRNA (guanine(2445)-N(2))-methyltransferase (71.4%) Methyltransferases (28.6%)" GO:0030488 (0.4%) "GO:0070043 (33%) GO:0003723 (32.6%) GO:0008990 (31.1%)" tRNA methylation (0.4%) "rRNA (guanine-N7-)-methyltransferase activity (33%) RNA binding (32.6%) rRNA (guanine-N2-)-methyltransferase activity (31.1%)" "IPR000241 (17.1%) IPR002052 (17.1%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.1%) DNA methylase, N-6 adenine-specific, conserved site (17.1%) THUMP domain (16.8%)" ELEAFSK root "7.1.2.2 (77.9%) 5.6.2.2 (6.8%) 2.7.2.3 (3.1%)" "H(+)-transporting two-sector ATPase (77.9%) DNA topoisomerase (ATP-hydrolyzing) (6.8%) phosphoglycerate kinase (3.1%)" "GO:0006265 (1%) GO:0006260 (0.9%) GO:0006094 (0.4%)" "GO:0045259 (12.5%) GO:0005886 (12.1%) GO:0005694 (1.1%)" "GO:0005524 (14.9%) GO:0043531 (12.9%) GO:0046933 (12.5%)" "DNA topological change (1%) DNA replication (0.9%) gluconeogenesis (0.4%)" "proton-transporting ATP synthase complex (12.5%) plasma membrane (12.1%) chromosome (1.1%)" "ATP binding (14.9%) ADP binding (12.9%) proton-transporting ATP synthase activity, rotational mechanism (12.5%)" "IPR027417 (8.2%) IPR000793 (7.6%) IPR005294 (7.6%)" "P-loop containing nucleoside triphosphate hydrolase (8.2%) ATP synthase, alpha subunit, C-terminal (7.6%) ATP synthase, F1 complex, alpha subunit (7.6%)" GLVTLLGATTENPSFEVLRPLLSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000731 (14.3%) GO:0006261 (14.3%)" "GO:0005524 (14.3%) GO:0008047 (14.3%) GO:0016887 (14.3%)" "DNA synthesis involved in DNA repair (14.3%) DNA-templated DNA replication (14.3%)" "ATP binding (14.3%) enzyme activator activity (14.3%) ATP hydrolysis activity (14.3%)" "IPR003593 (14.3%) IPR003959 (14.3%) IPR021886 (14.3%)" "AAA+ ATPase domain (14.3%) ATPase, AAA-type, core (14.3%) MgsA AAA+ ATPase, C-terminal (14.3%)" ELVQWGVNFDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.8%) GO:0005737 (32.4%) GO:0008734 (33.8%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.8%) cytoplasm (32.4%) L-aspartate oxidase activity (33.8%) "IPR003953 (17.2%) IPR005288 (17.2%) IPR015939 (16.6%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17.2%) L-aspartate oxidase (17.2%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.6%)" VSDCQFLGTDVGLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005975 (44.3%) "GO:0004650 (44.3%) GO:0004557 (11.4%)" carbohydrate metabolic process (44.3%) "polygalacturonase activity (44.3%) alpha-galactosidase activity (11.4%)" "IPR000743 (20.5%) IPR006626 (20.5%) IPR051801 (20.5%)" "Glycoside hydrolase, family 28 (20.5%) Parallel beta-helix repeat (20.5%) Glycosyl_Hydrolase_28_Enzymes (20.5%)" LQELNSDYEAKR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005737 (50%) GO:0016881 (50%) cytoplasm (50%) acid-amino acid ligase activity (50%) "IPR004993 (30.3%) IPR055377 (30.3%) IPR055378 (30.3%)" "GH3 family (30.3%) GH3, middle domain (30.3%) GH3, C-terminal domain (30.3%)" QLSDHPYDVLLGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.4 (100%) DNA 3'-5' helicase (100%) "GO:0006269 (10%) GO:0006270 (10%) GO:0006302 (10%)" GO:1990077 (10%) "GO:0003677 (10%) GO:0005524 (10%) GO:0008270 (10%)" "DNA replication, synthesis of primer (10%) DNA replication initiation (10%) double-strand break repair (10%)" primosome complex (10%) "DNA binding (10%) ATP binding (10%) zinc ion binding (10%)" "IPR001650 (11.1%) IPR005259 (11.1%) IPR011545 (11.1%)" "Helicase, C-terminal domain-like (11.1%) Primosomal protein N' (11.1%) DEAD/DEAH-box helicase domain (11.1%)" TPSTLKDEDYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (24.9%) GO:0016887 (24.9%) GO:0051082 (24.9%)" "ATP binding (24.9%) ATP hydrolysis activity (24.9%) unfolded protein binding (24.9%)" "IPR001404 (18.8%) IPR020568 (18.8%) IPR020575 (18.8%)" "Heat shock protein Hsp90 family (18.8%) Ribosomal protein uS5 domain 2-type superfamily (18.8%) Heat shock protein Hsp90, N-terminal (18.8%)" YGYGVVR root "3.4.11.18 (95.6%) 3.4.19.12 (1.5%) 3.-.-.- (0.7%)" "methionyl aminopeptidase (95.6%) ubiquitinyl hydrolase 1 (1.5%) Hydrolases (0.7%)" "GO:0006508 (19.4%) GO:0000448 (0.5%) GO:0006813 (0.2%)" "GO:0005829 (9.9%) GO:0005886 (3.8%) GO:0009507 (1.3%)" "GO:0070006 (19%) GO:0004239 (18%) GO:0046914 (15.8%)" "proteolysis (19.4%) cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.5%) potassium ion transport (0.2%)" "cytosol (9.9%) plasma membrane (3.8%) chloroplast (1.3%)" "metalloaminopeptidase activity (19%) initiator methionyl aminopeptidase activity (18%) transition metal ion binding (15.8%)" "IPR000994 (19.1%) IPR036005 (18.9%) IPR001714 (18.5%)" "Peptidase M24 (19.1%) Creatinase/aminopeptidase-like (18.9%) Peptidase M24, methionine aminopeptidase (18.5%)" LTSGTLPYELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MDDTLNELLPDDPNQAYDMYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015977 (21%) GO:0006633 (12.9%)" GO:0009317 (21%) "GO:0004658 (22.6%) GO:0003989 (21%) GO:0016740 (1.6%)" "carbon fixation (21%) fatty acid biosynthetic process (12.9%)" acetyl-CoA carboxylase complex (21%) "propionyl-CoA carboxylase activity (22.6%) acetyl-CoA carboxylase activity (21%) transferase activity (1.6%)" "IPR011762 (18.4%) IPR011763 (18.4%) IPR034733 (18.4%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.4%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.4%)" YLGSATATSADLPMSADEAVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (37.1%) IPR012944 (37.1%) IPR033985 (25.7%)" "Tetratricopeptide-like helical domain superfamily (37.1%) RagB/SusD domain (37.1%) SusD-like, N-terminal (25.7%)" LTESCEMVVNLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.6%) IPR013148 (14.6%) IPR013189 (14.6%)" "Glycoside hydrolase, family 32 (14.6%) Glycosyl hydrolase family 32, N-terminal (14.6%) Glycosyl hydrolase family 32, C-terminal (14.6%)" WGEANELTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006101 (8.3%) IPR006102 (8.3%) IPR006103 (8.3%)" "Glycoside hydrolase, family 2 (8.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8.3%) Glycoside hydrolase family 2, catalytic domain (8.3%)" GYYMLGQLNGNEWDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR033408 (100%) Outer membrane protein SusF, N-terminal domain (100%) CFQDLTPEEQQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008886 (33.3%) IPR023214 (33.3%) IPR029058 (33.3%)" "Uncharacterised protein family UPF0227/Esterase YqiA (33.3%) HAD superfamily (33.3%) Alpha/Beta hydrolase fold (33.3%)" QYGNSVAPLLLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004386 (100%) helicase activity (100%) "IPR007936 (33.3%) IPR014907 (33.3%) IPR024450 (33.3%)" "Virulence-associated protein E-like domain (33.3%) BT4734-like, N-terminal (33.3%) Domain of unknown function DUF3874 (33.3%)" RADGSYLR root 2.7.4.1 (100%) ATP-polyphosphate phosphotransferase (100%) "GO:0006412 (24.8%) GO:0006260 (0%) GO:0006508 (0%)" "GO:0022625 (24.6%) GO:0005762 (0.2%) GO:0005840 (0.2%)" "GO:0003735 (24.8%) GO:0070180 (24.8%) GO:0005524 (0.1%)" "translation (24.8%) DNA replication (0%) proteolysis (0%)" "cytosolic large ribosomal subunit (24.6%) mitochondrial large ribosomal subunit (0.2%) ribosome (0.2%)" "structural constituent of ribosome (24.8%) large ribosomal subunit rRNA binding (24.8%) ATP binding (0.1%)" "IPR000218 (25.2%) IPR036853 (25.2%) IPR005745 (25.1%)" "Large ribosomal subunit protein uL14 (25.2%) Large ribosomal subunit protein uL14 superfamily (25.2%) Large ribosomal subunit protein uL14, bacteria (25.1%)" TLQDWLVR root 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0006364 (0.1%) GO:0006396 (0.1%) GO:0007018 (0.1%)" "GO:0005886 (26.3%) GO:0005737 (0.1%) GO:0005874 (0.1%)" "GO:0042910 (26.3%) GO:0008324 (26%) GO:0015562 (20.4%)" "rRNA processing (0.1%) RNA processing (0.1%) microtubule-based movement (0.1%)" "plasma membrane (26.3%) cytoplasm (0.1%) microtubule (0.1%)" "xenobiotic transmembrane transporter activity (26.3%) monoatomic cation transmembrane transporter activity (26%) efflux transmembrane transporter activity (20.4%)" "IPR001036 (26.3%) IPR027463 (26.1%) IPR004763 (26%)" "Acriflavin resistance protein (26.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (26.1%) Cation efflux system CusA-like (26%)" VGDEVEAVLLTLDRAER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" FGFFPAFSLGWR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (13.1%) IPR012910 (12.7%) IPR023997 (12.7%)" "TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" LLFVGDVVATQLDATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) GO:0016020 (49.4%) "GO:0004467 (49.4%) GO:0016874 (1.3%)" membrane (49.4%) "long-chain fatty acid-CoA ligase activity (49.4%) ligase activity (1.3%)" "IPR000873 (25.8%) IPR020845 (25.2%) IPR042099 (24.5%)" "AMP-dependent synthetase/ligase domain (25.8%) AMP-binding, conserved site (25.2%) ANL, N-terminal domain (24.5%)" LANNYLFADLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (33.3%) "GO:0010285 (33.3%) GO:0030170 (33.3%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (33.3%) "L,L-diaminopimelate aminotransferase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (22.2%) IPR019942 (22.2%) IPR015421 (18.5%)" "Aminotransferase, class I/classII, large domain (22.2%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (22.2%) Pyridoxal phosphate-dependent transferase, major domain (18.5%)" VENYKELGLNSETCVAFNVTSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.3%) GO:0005829 (17.3%) "GO:0004612 (17.3%) GO:0005524 (17.3%) GO:0046872 (17.3%)" gluconeogenesis (17.3%) cytosol (17.3%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.3%) ATP binding (17.3%) metal ion binding (17.3%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" MSCELLETGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0035435 (33.3%) GO:0016020 (33.3%) GO:0005315 (33.3%) phosphate ion transmembrane transport (33.3%) membrane (33.3%) phosphate transmembrane transporter activity (33.3%) IPR001204 (100%) Phosphate transporter (100%) SLNDFLSSFHVEGESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000162 (51.9%) GO:0046872 (48.1%) L-tryptophan biosynthetic process (51.9%) metal ion binding (48.1%) "IPR006805 (25.5%) IPR015890 (25.5%) IPR019999 (25.5%)" "Anthranilate synthase component I, N-terminal (25.5%) Chorismate-utilising enzyme, C-terminal (25.5%) Anthranilate synthase component I-like (25.5%)" YQLDKLELAVADELWTLPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.3%) IPR008147 (14.3%) IPR014746 (14.3%)" "Glutamine synthetase, catalytic domain (14.3%) Glutamine synthetase, N-terminal domain (14.3%) Glutamine synthetase/guanido kinase, catalytic domain (14.3%)" DFTWTTDFNLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" EEVTAAEDALQVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" YLGGSGLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" ANLDAQLK root "3.2.1.39 (54.5%) 1.3.1.9 (9.1%) 2.5.1.120 (9.1%)" "glucan endo-1,3-beta-D-glucosidase (54.5%) enoyl-[acyl-carrier-protein] reductase (NADH) (9.1%) aminodeoxyfutalosine synthase (9.1%)" "GO:0005975 (4%) GO:0006952 (4%) GO:0006887 (1.3%)" "GO:0009279 (30%) GO:0005886 (6%) GO:0009506 (4%)" "GO:0004553 (4%) GO:0046872 (2%) GO:0004130 (1.3%)" "carbohydrate metabolic process (4%) defense response (4%) exocytosis (1.3%)" "cell outer membrane (30%) plasma membrane (6%) plasmodesma (4%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (4%) metal ion binding (2%) cytochrome-c peroxidase activity (1.3%)" "IPR012910 (10.3%) IPR023996 (10.3%) IPR023997 (10.3%)" "TonB-dependent receptor, plug domain (10.3%) TonB-dependent outer membrane protein, SusC/RagA (10.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (10.3%)" SFQAAPGGLANNSVWCLAEDPYHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (18.8%) "GO:0000155 (20.3%) GO:0003700 (20.3%) GO:0005524 (20.3%)" membrane (18.8%) "phosphorelay sensor kinase activity (20.3%) DNA-binding transcription factor activity (20.3%) ATP binding (20.3%)" "IPR001789 (6.8%) IPR003594 (6.8%) IPR003661 (6.8%)" "Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%)" ATTVEELKELLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) "GO:0000049 (33.3%) GO:0017150 (33.3%) GO:0050660 (33.3%)" "tRNA binding (33.3%) tRNA dihydrouridine synthase activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001269 (16.7%) IPR004652 (16.7%) IPR013785 (16.7%)" "tRNA-dihydrouridine synthase (16.7%) tRNA-dihydrouridine synthase DusB-like (16.7%) Aldolase-type TIM barrel (16.7%)" HELDPDGGYVLSMER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (7.1%) IPR006101 (7.1%) IPR006102 (7.1%)" "Beta galactosidase small chain/ domain 5 (7.1%) Glycoside hydrolase, family 2 (7.1%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.1%)" RFPNEPEYLQAVSQVLGTLEEEYNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006537 (25.6%) GO:0005829 (25.6%) "GO:0004354 (25.6%) GO:0000166 (23.2%)" glutamate biosynthetic process (25.6%) cytosol (25.6%) "glutamate dehydrogenase (NADP+) activity (25.6%) nucleotide binding (23.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" ENPLVTVR root 2.1.1.386 (100%) small RNA 2'-O-methyltransferase (100%) "GO:0006811 (14.5%) GO:0006508 (0.9%) GO:0001510 (0.4%)" "GO:0009279 (14.5%) GO:0046930 (14.5%) GO:0016020 (8.9%)" "GO:0015159 (23.8%) GO:0015288 (14.5%) GO:0004198 (0.9%)" "monoatomic ion transport (14.5%) proteolysis (0.9%) RNA methylation (0.4%)" "cell outer membrane (14.5%) pore complex (14.5%) membrane (8.9%)" "polysaccharide transmembrane transporter activity (23.8%) porin activity (14.5%) calcium-dependent cysteine-type endopeptidase activity (0.9%)" "IPR003715 (28.1%) IPR049712 (28.1%) IPR054765 (17.1%)" "Polysaccharide export protein, N-terminal domain (28.1%) Polysaccharide export protein (28.1%) SLBB domain (17.1%)" SDLSGASVSMGEDQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.9%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.9%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" SSYTLDANGNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) ENPDYLVYR Bacteria Bacteria 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) "GO:0006508 (38.5%) GO:0006281 (7.7%)" GO:0005829 (7.7%) "GO:0008234 (38.5%) GO:0008967 (7.7%)" "proteolysis (38.5%) DNA repair (7.7%)" cytosol (7.7%) "cysteine-type peptidase activity (38.5%) phosphoglycolate phosphatase activity (7.7%)" "IPR000200 (14.7%) IPR026906 (14.7%) IPR032675 (14.7%)" "Peptidase C10, streptopain (14.7%) BspA-type LRR region (14.7%) Leucine-rich repeat domain superfamily (14.7%)" EVDVQVLK root 1.97.1.12 (100%) photosystem I (100%) "GO:0006412 (7.4%) GO:2000762 (3.8%) GO:0015833 (1.9%)" "GO:0016020 (37.5%) GO:0022625 (7.4%) GO:0016592 (3.8%)" "GO:0003735 (7.4%) GO:0019843 (7.4%) GO:1904680 (1.9%)" "translation (7.4%) regulation of phenylpropanoid metabolic process (3.8%) peptide transport (1.9%)" "membrane (37.5%) cytosolic large ribosomal subunit (7.4%) mediator complex (3.8%)" "structural constituent of ribosome (7.4%) rRNA binding (7.4%) peptide transmembrane transporter activity (1.9%)" "IPR006665 (20.1%) IPR050330 (20.1%) IPR036737 (19.7%)" "OmpA-like domain (20.1%) Bacterial Outer Membrane Structural/Functional (20.1%) OmpA-like domain superfamily (19.7%)" AFFQDTEQWLVPYAQYSYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" GDLLGGVSVVDVEGLMKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.3%) IPR023996 (31.4%) IPR037066 (31.4%)" "TonB-dependent receptor, plug domain (34.3%) TonB-dependent outer membrane protein, SusC/RagA (31.4%) TonB-dependent receptor, plug domain superfamily (31.4%)" NVNLHGYLLDSQTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0004089 (50%) GO:0008270 (50%)" "carbonate dehydratase activity (50%) zinc ion binding (50%)" "IPR001765 (50%) IPR036874 (50%)" "Carbonic anhydrase (50%) Carbonic anhydrase superfamily (50%)" LNQEPFLESVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (16%) IPR039426 (16%) IPR012910 (14.2%)" "TonB-dependent outer membrane protein, SusC/RagA (16%) TonB-dependent receptor-like (16%) TonB-dependent receptor, plug domain (14.2%)" AEDLESFK root 6.1.1.16 (100%) cysteine--tRNA ligase (100%) "GO:0006260 (1%) GO:0006423 (1%) GO:0032468 (1%)" "GO:0016020 (1.9%) GO:0000329 (1%) GO:0000775 (1%)" "GO:0016627 (35%) GO:0050660 (35%) GO:1902936 (1.9%)" "DNA replication (1%) cysteinyl-tRNA aminoacylation (1%) Golgi calcium ion homeostasis (1%)" "membrane (1.9%) fungal-type vacuole membrane (1%) chromosome, centromeric region (1%)" "oxidoreductase activity, acting on the CH-CH group of donors (35%) flavin adenine dinucleotide binding (35%) phosphatidylinositol bisphosphate binding (1.9%)" "IPR006091 (9.2%) IPR009075 (9.2%) IPR013786 (9.2%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (9.2%) Acyl-CoA dehydrogenase/oxidase, C-terminal (9.2%) Acyl-CoA dehydrogenase/oxidase, N-terminal (9.2%)" LKNVELAYTWTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" ELSGLLGFSNTSFFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (39.7%) IPR009057 (36.5%) IPR037923 (20.6%)" "AraC-like, DNA binding HTH domain (39.7%) Homedomain-like superfamily (36.5%) Transcription regulator HTH-like (20.6%)" GVACLVNFDPVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.5%) "GO:0016787 (50%) GO:0016798 (1.5%)" carbohydrate metabolic process (48.5%) "hydrolase activity (50%) hydrolase activity, acting on glycosyl bonds (1.5%)" "IPR008979 (16.7%) IPR012878 (16.7%) IPR049046 (16.7%)" "Galactose-binding-like domain superfamily (16.7%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.7%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.7%)" SFEFPQR root "3.2.1.55 (96.1%) 1.13.11.27 (1.3%) 2.4.1.34 (1.3%)" "non-reducing end alpha-L-arabinofuranosidase (96.1%) 4-hydroxyphenylpyruvate dioxygenase (1.3%) 1,3-beta-glucan synthase (1.3%)" "GO:0046373 (24%) GO:0016192 (6.2%) GO:0006605 (4.7%)" "GO:0005765 (4.7%) GO:0031085 (4.7%) GO:0031410 (4.7%)" "GO:0046556 (24.6%) GO:0031267 (5%) GO:0005085 (4.7%)" "L-arabinose metabolic process (24%) vesicle-mediated transport (6.2%) protein targeting (4.7%)" "lysosomal membrane (4.7%) BLOC-3 complex (4.7%) cytoplasmic vesicle (4.7%)" "alpha-L-arabinofuranosidase activity (24.6%) small GTPase binding (5%) guanyl-nucleotide exchange factor activity (4.7%)" "IPR003305 (12.3%) IPR051563 (12.3%) IPR010720 (12%)" "Carbohydrate-binding, CenC-like (12.3%) Glycosyl Hydrolase Family 51 (12.3%) Alpha-L-arabinofuranosidase, C-terminal (12%)" NMSANCYAPVAGVGLLNEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (25%) IPR011250 (25%) IPR036737 (25%)" "OmpA-like domain (25%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (25%) OmpA-like domain superfamily (25%)" SLYELFR root "2.7.13.3 (14.3%) 1.2.1.3 (9.5%) 3.1.21.- (9.5%)" "histidine kinase (14.3%) aldehyde dehydrogenase (NAD(+)) (9.5%) Endodeoxyribonucleases producing 5'-phosphomonoesters (9.5%)" "GO:0007015 (2.3%) GO:0019722 (1.9%) GO:0030833 (1.5%)" "GO:0016020 (8.2%) GO:0005737 (4%) GO:0009279 (2.6%)" "GO:0005524 (4.8%) GO:0000146 (2.5%) GO:0051015 (2.5%)" "actin filament organization (2.3%) calcium-mediated signaling (1.9%) regulation of actin filament polymerization (1.5%)" "membrane (8.2%) cytoplasm (4%) cell outer membrane (2.6%)" "ATP binding (4.8%) microfilament motor activity (2.5%) actin filament binding (2.5%)" "IPR027417 (4.4%) IPR011990 (2.2%) IPR012944 (2.1%)" "P-loop containing nucleoside triphosphate hydrolase (4.4%) Tetratricopeptide-like helical domain superfamily (2.2%) RagB/SusD domain (2.1%)" KDYMGNVMVNFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LALLFLAR root "2.3.2.6 (27.1%) 3.5.2.6 (20%) 3.4.21.89 (11.4%)" "lysine/arginine leucyltransferase (27.1%) beta-lactamase (20%) signal peptidase I (11.4%)" "GO:1902600 (4.4%) GO:0006813 (3.7%) GO:0008360 (2.4%)" "GO:0005886 (15.5%) GO:0016020 (9%) GO:0005737 (1.7%)" "GO:0015297 (4.6%) GO:0008324 (3.6%) GO:0022857 (3.2%)" "proton transmembrane transport (4.4%) potassium ion transport (3.7%) regulation of cell shape (2.4%)" "plasma membrane (15.5%) membrane (9%) cytoplasm (1.7%)" "antiporter activity (4.6%) monoatomic cation transmembrane transporter activity (3.6%) transmembrane transporter activity (3.2%)" "IPR006153 (3.7%) IPR038770 (3.5%) IPR006037 (3%)" "Cation/H+ exchanger, transmembrane domain (3.7%) Sodium/solute symporter superfamily (3.5%) Regulator of K+ conductance, C-terminal (3%)" LSNNLGLEYDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.41 (100%) Transferred entry: 7.2.4.3 (100%) GO:0006814 (33.3%) GO:0005886 (33.3%) GO:0016829 (33.3%) sodium ion transport (33.3%) plasma membrane (33.3%) lyase activity (33.3%) "IPR005661 (69.7%) IPR038770 (30.3%)" "Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit (69.7%) Sodium/solute symporter superfamily (30.3%)" RLELCFENK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR011990 (33.3%) IPR033985 (32.5%)" "RagB/SusD domain (34.2%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (32.5%)" VWDCLPYAGVGLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (25%) IPR011250 (25%) IPR036737 (25%)" "OmpA-like domain (25%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (25%) OmpA-like domain superfamily (25%)" SPLGPYTYHGTLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR000421 (16.7%) IPR006710 (16.7%) IPR008979 (16.7%)" "Coagulation factor 5/8, C-terminal domain (16.7%) Glycoside hydrolase, family 43 (16.7%) Galactose-binding-like domain superfamily (16.7%)" TPQHEACTDLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR012547 (50%) IPR018631 (50%)" "PD-(D/E)XK nuclease superfamily 9 (50%) AAA-ATPase-like domain (50%)" FGLNVLGVK root GO:0006813 (31.6%) "GO:0005886 (31.6%) GO:0005743 (1.7%) GO:0045259 (1.7%)" "GO:0008324 (31.6%) GO:0046933 (1.7%)" potassium ion transport (31.6%) "plasma membrane (31.6%) mitochondrial inner membrane (1.7%) proton-transporting ATP synthase complex (1.7%)" "monoatomic cation transmembrane transporter activity (31.6%) proton-transporting ATP synthase activity, rotational mechanism (1.7%)" "IPR004680 (23.9%) IPR006037 (23.9%) IPR051679 (23.9%)" "Citrate transporter-like domain (23.9%) Regulator of K+ conductance, C-terminal (23.9%) Divalent Anion Sodium Symporter-Related Transporters (23.9%)" VKDGLNEWLDAHGCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.3.-.- (100%) Acting on the CH-CH group of donors (100%) "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" ELTDVDLVVGSVLVPGDKAPHLLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25%) GO:0005886 (25%) "GO:0000166 (25%) GO:0000286 (25%)" L-alanine catabolic process (25%) plasma membrane (25%) "nucleotide binding (25%) alanine dehydrogenase activity (25%)" "IPR007698 (20%) IPR007886 (20%) IPR008141 (20%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20%) Alanine dehydrogenase (20%)" FENLTGMTMFLYTGPYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR040475 (29.5%) IPR013783 (27.3%) IPR014756 (27.3%)" "Surface glycan-binding protein B, xyloglucan binding domain (29.5%) Immunoglobulin-like fold (27.3%) Immunoglobulin E-set (27.3%)" QQNLLMSLYALLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0015079 (33.3%) GO:0015293 (33.3%)" plasma membrane (33.3%) "potassium ion transmembrane transporter activity (33.3%) symporter activity (33.3%)" "IPR053952 (25.6%) IPR003855 (24.8%) IPR023051 (24.8%)" "K+ potassium transporter, C-terminal domain (25.6%) Potassium transporter (24.8%) Low affinity potassium transport system protein Kup (24.8%)" LLLMGAGK root "1.3.1.12 (50%) 4.2.1.51 (25%) 5.4.99.5 (25%)" "prephenate dehydrogenase (50%) prephenate dehydratase (25%) chorismate mutase (25%)" "GO:0006571 (20.2%) GO:0006635 (1.8%) GO:0000271 (0.4%)" "GO:0005886 (1.8%) GO:0016020 (0.9%) GO:0005829 (0.4%)" "GO:0070403 (22.4%) GO:0004665 (20.2%) GO:0008977 (20.2%)" "L-tyrosine biosynthetic process (20.2%) fatty acid beta-oxidation (1.8%) polysaccharide biosynthetic process (0.4%)" "plasma membrane (1.8%) membrane (0.9%) cytosol (0.4%)" "NAD+ binding (22.4%) prephenate dehydrogenase (NADP+) activity (20.2%) prephenate dehydrogenase (NAD+) activity (20.2%)" "IPR036291 (18%) IPR008927 (17%) IPR003099 (15.6%)" "NAD(P)-binding domain superfamily (18%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (17%) Prephenate dehydrogenase (15.6%)" LLLTTEK root "2.7.1.130 (86.9%) 2.7.13.3 (3.1%) 2.7.7.43 (0.8%)" "tetraacyldisaccharide 4'-kinase (86.9%) histidine kinase (3.1%) N-acylneuraminate cytidylyltransferase (0.8%)" "GO:0009245 (13%) GO:0009244 (10.7%) GO:0007156 (0.7%)" "GO:0005886 (14.5%) GO:0016020 (2.5%) GO:0005737 (1%)" "GO:0005524 (14.4%) GO:0009029 (12.9%) GO:0003677 (1.1%)" "lipid A biosynthetic process (13%) lipopolysaccharide core region biosynthetic process (10.7%) homophilic cell-cell adhesion (0.7%)" "plasma membrane (14.5%) membrane (2.5%) cytoplasm (1%)" "ATP binding (14.4%) lipid-A 4'-kinase activity (12.9%) DNA binding (1.1%)" "IPR027417 (16%) IPR003758 (15.4%) IPR013320 (1%)" "P-loop containing nucleoside triphosphate hydrolase (16%) Tetraacyldisaccharide 4'-kinase (15.4%) Concanavalin A-like lectin/glucanase domain superfamily (1%)" LLTFGPR root "2.1.1.35 (47.5%) 3.1.3.48 (14.8%) 2.1.1.- (8.2%)" "tRNA (uracil(54)-C(5))-methyltransferase (47.5%) protein-tyrosine-phosphatase (14.8%) Methyltransferases (8.2%)" "GO:0006004 (11.4%) GO:0032259 (3.2%) GO:0008033 (2.6%)" "GO:0005737 (13%) GO:0016020 (12.8%) GO:0033573 (2.9%)" "GO:0008736 (11.4%) GO:0022857 (5.5%) GO:0004252 (3.8%)" "fucose metabolic process (11.4%) methylation (3.2%) tRNA processing (2.6%)" "cytoplasm (13%) membrane (12.8%) high-affinity iron permease complex (2.9%)" "L-fucose isomerase activity (11.4%) transmembrane transporter activity (5.5%) serine-type endopeptidase activity (3.8%)" "IPR009015 (8.9%) IPR015888 (8.6%) IPR011701 (4%)" "L-fucose isomerase, N-terminal/central domain superfamily (8.9%) L-fucose isomerase, C-terminal (8.6%) Major facilitator superfamily (4%)" LVLQTVK root "1.5.1.2 (40%) 5.6.2.- (18%) 2.1.1.113 (4%)" "pyrroline-5-carboxylate reductase (40%) Enzymes altering nucleic acid conformation (18%) site-specific DNA-methyltransferase (cytosine-N(4)-specific) (4%)" "GO:0010468 (6%) GO:0034087 (6%) GO:0071169 (6%)" "GO:0090694 (6%) GO:0005737 (3.2%) GO:0005829 (3.1%)" "GO:0003682 (6.1%) GO:0061775 (6%) GO:0043565 (2.3%)" "regulation of gene expression (6%) establishment of mitotic sister chromatid cohesion (6%) establishment of protein localization to chromatin (6%)" "Scc2-Scc4 cohesin loading complex (6%) cytoplasm (3.2%) cytosol (3.1%)" "chromatin binding (6.1%) cohesin loader activity (6%) sequence-specific DNA binding (2.3%)" "IPR024986 (5.9%) IPR016024 (5.9%) IPR033031 (5.9%)" "Sister chromatid cohesion C-terminal domain (5.9%) Armadillo-type fold (5.9%) Scc2/Nipped-B family (5.9%)" LKDLLMSLYQTTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.1%) IPR012547 (33.3%) IPR027417 (28.6%)" "AAA-ATPase-like domain (38.1%) PD-(D/E)XK nuclease superfamily 9 (33.3%) P-loop containing nucleoside triphosphate hydrolase (28.6%)" VTLTAWDLDVTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" LASAFLEAFCTLSQDQLQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.4.16 (50%) 6.3.5.5 (50%)" "carbamoyl-phosphate synthase (ammonia) (50%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50%)" "GO:0006541 (14.4%) GO:0006221 (13.8%) GO:0006526 (13.8%)" GO:0005737 (14.4%) "GO:0004088 (14.4%) GO:0005524 (14.4%) GO:0046872 (13.8%)" "glutamine metabolic process (14.4%) pyrimidine nucleotide biosynthetic process (13.8%) L-arginine biosynthetic process (13.8%)" cytoplasm (14.4%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.4%) ATP binding (14.4%) metal ion binding (13.8%)" "IPR011607 (10.3%) IPR036914 (10.3%) IPR005479 (9.9%)" "Methylglyoxal synthase-like domain (10.3%) Methylglyoxal synthase-like domain superfamily (10.3%) Carbamoyl phosphate synthase, ATP-binding domain (9.9%)" AGVGSVMSSFNLLDYLPATANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.3%) IPR002772 (11.3%) IPR019800 (11.3%)" "Glycoside hydrolase, family 3, N-terminal (11.3%) Glycoside hydrolase family 3 C-terminal domain (11.3%) Glycoside hydrolase, family 3, active site (11.3%)" RLPMTEMSVDDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.69 (100%) gluconate 5-dehydrogenase (100%) "GO:0008874 (53.8%) GO:0016491 (46.2%)" "gluconate 5-dehydrogenase activity (53.8%) oxidoreductase activity (46.2%)" "IPR002347 (31%) IPR020904 (31%) IPR036291 (31%)" "Short-chain dehydrogenase/reductase SDR (31%) Short-chain dehydrogenase/reductase, conserved site (31%) NAD(P)-binding domain superfamily (31%)" LTEFKDDYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043741 (100%) Family of unknown function DUF5686 (100%) ALTFVSEEDQYWFQQLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005829 (20.2%) "GO:0003724 (20.2%) GO:0005524 (20.2%) GO:0003676 (19.7%)" cytosol (20.2%) "RNA helicase activity (20.2%) ATP binding (20.2%) nucleic acid binding (19.7%)" "IPR001650 (14.7%) IPR050079 (14.7%) IPR000629 (14.3%)" "Helicase, C-terminal domain-like (14.7%) DEAD box RNA helicase (14.7%) ATP-dependent RNA helicase DEAD-box, conserved site (14.3%)" VHASALSYTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (18.8%) IPR002890 (18.8%) IPR051802 (18.8%)" "Alpha-2-macroglobulin (18.8%) Macroglobulin domain (18.8%) Alpha-2-macroglobulin-like (18.8%)" VVKPATALNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045900 (33.3%) GO:0022627 (33.3%) GO:0043024 (33.3%) negative regulation of translational elongation (33.3%) cytosolic small ribosomal subunit (33.3%) ribosomal small subunit binding (33.3%) "IPR003489 (48.3%) IPR036567 (48.3%) IPR050574 (3.4%)" "Ribosome hibernation promoting factor/RaiA (48.3%) Ribosome hibernation promotion factor-like (48.3%) HPF/YfiA ribosome-associated (3.4%)" SLSLLEYSGQSEPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (11.8%) GO:0009279 (76.5%) GO:0015344 (11.8%) siderophore transmembrane transport (11.8%) cell outer membrane (76.5%) siderophore uptake transmembrane transporter activity (11.8%) "IPR000531 (14.4%) IPR036942 (14.4%) IPR039426 (14.4%)" "TonB-dependent receptor-like, beta-barrel (14.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.4%) TonB-dependent receptor-like (14.4%)" VLMMLTPETSEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005829 (50%) GO:0004834 (50%) cytosol (50%) tryptophan synthase activity (50%) "IPR002028 (25.6%) IPR011060 (24.8%) IPR013785 (24.8%)" "Tryptophan synthase, alpha chain (25.6%) Ribulose-phosphate binding barrel (24.8%) Aldolase-type TIM barrel (24.8%)" LVFTTAFK Pseudomonadati Bacteria Pseudomonadati GO:0009306 (10.7%) GO:0005886 (10.7%) "GO:0000156 (39.3%) GO:0003677 (39.3%)" protein secretion (10.7%) plasma membrane (10.7%) "phosphorelay response regulator activity (39.3%) DNA binding (39.3%)" "IPR001789 (22.4%) IPR007492 (22.4%) IPR046947 (22.4%)" "Signal transduction response regulator, receiver domain (22.4%) LytTR DNA-binding domain (22.4%) Transcriptional regulatory protein LytR-like (22.4%)" EKNENLWLAQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0019698 (33.6%) GO:0042840 (33.6%)" GO:0016746 (32.7%) "D-galacturonate catabolic process (33.6%) D-glucuronate catabolic process (33.6%)" acyltransferase activity (32.7%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) TPQLYYGTEVLMNGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.19 (100%) cyclomaltodextrin glucanotransferase (100%) GO:0005975 (49.4%) "GO:0016798 (49.4%) GO:0043895 (1.3%)" carbohydrate metabolic process (49.4%) "hydrolase activity, acting on glycosyl bonds (49.4%) cyclomaltodextrin glucanotransferase activity (1.3%)" "IPR006047 (14.7%) IPR015171 (14.7%) IPR019492 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (14.7%) Cyclomaltodextrinase, N-terminal (14.7%) Cyclo-malto-dextrinase, C-terminal (14.7%)" AGLDKFNVLTGDMVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20%) IPR012910 (20%) IPR036942 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" FVTDKDHFSNLGVTMPTLGAENK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.5%) IPR012910 (13.5%) IPR023996 (13.5%)" "TonB-dependent receptor-like, beta-barrel (13.5%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%)" LQVDELDADLLEDVNLEMTQAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.1.32 (100%) phospholipase A1 (100%) GO:0016020 (49.2%) "GO:0046873 (49.2%) GO:0008970 (1.5%)" membrane (49.2%) "metal ion transmembrane transporter activity (49.2%) phospholipase A1 activity (1.5%)" "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" SGSENDEYNASVQALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000272 (31.3%) GO:0005576 (31.3%) "GO:0030570 (31.3%) GO:0004557 (6.3%)" polysaccharide catabolic process (31.3%) extracellular region (31.3%) "pectate lyase activity (31.3%) alpha-galactosidase activity (6.3%)" "IPR002022 (17.9%) IPR011050 (17.9%) IPR012334 (17.9%)" "Pectate lyase (17.9%) Pectin lyase fold/virulence factor (17.9%) Pectin lyase fold (17.9%)" VLFDLCGK root "GO:0009451 (3.9%) GO:0006508 (2%) GO:0075523 (2%)" "GO:0005739 (3.9%) GO:0016020 (2%)" "GO:0016747 (35.3%) GO:0016788 (33.3%) GO:0003723 (4.9%)" "RNA modification (3.9%) proteolysis (2%) viral translational frameshifting (2%)" "mitochondrion (3.9%) membrane (2%)" "acyltransferase activity, transferring groups other than amino-acyl groups (35.3%) hydrolase activity, acting on ester bonds (33.3%) RNA binding (4.9%)" "IPR000801 (15.3%) IPR005181 (15.3%) IPR050583 (15.3%)" "Esterase-like (15.3%) Sialate O-acetylesterase domain (15.3%) Mycobacterial A85 antigen (15.3%)" MNLEGLDYNTQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR025632 (100%) Protein of unknown function DUF4290 (100%) PAVLDFYTTWCGPCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045454 (22.2%) "GO:0005829 (22.2%) GO:0016020 (3.7%)" GO:0015035 (51.9%) cell redox homeostasis (22.2%) "cytosol (22.2%) membrane (3.7%)" protein-disulfide reductase activity (51.9%) "IPR005746 (25.5%) IPR013766 (25.5%) IPR017937 (25.5%)" "Thioredoxin (25.5%) Thioredoxin domain (25.5%) Thioredoxin, conserved site (25.5%)" VYLLHADELYYDMFGNNPDAQLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (36%) GO:1990351 (36%) GO:0016020 (28%)" "cell outer membrane (36%) transporter complex (36%) membrane (28%)" "IPR005653 (66.7%) IPR050218 (33.3%)" "Organic solvent tolerance-like, N-terminal (66.7%) Lipopolysaccharide Assembly Protein LptD (33.3%)" EETDDWWNGMNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.8%) IPR015171 (14.8%) IPR019492 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Cyclomaltodextrinase, N-terminal (14.8%) Cyclo-malto-dextrinase, C-terminal (14.8%)" EPGKPVVFFTGDSTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR001087 (25%) IPR013830 (25%) IPR036514 (25%)" "GDSL lipase/esterase (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" KDLLAPSVK Pseudomonadati Bacteria Pseudomonadati "2.3.2.2 (50%) 3.4.19.13 (33.3%) 6.3.2.9 (16.7%)" "gamma-glutamyltransferase (50%) glutathione gamma-glutamate hydrolase (33.3%) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase (16.7%)" "GO:0008360 (2%) GO:0009252 (2%) GO:0051301 (2%)" "GO:0016020 (58.8%) GO:0005737 (2%)" "GO:0036374 (7.8%) GO:0103068 (7.8%) GO:0016787 (5.9%)" "regulation of cell shape (2%) peptidoglycan biosynthetic process (2%) cell division (2%)" "membrane (58.8%) cytoplasm (2%)" "glutathione hydrolase activity (7.8%) leukotriene C4 gamma-glutamyl transferase activity (7.8%) hydrolase activity (5.9%)" "IPR013105 (21.2%) IPR019734 (21.2%) IPR025738 (21.2%)" "Tetratricopeptide repeat 2 (21.2%) Tetratricopeptide repeat (21.2%) Aerotolerance-related protein BatD (21.2%)" NAQVDLTQLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025935 (100%) Bacteriophage abortive infection AbiH (100%) NSALCDREEFEQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) KPEYLEAATR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.3.11 (100%) cellobiose epimerase (100%) GO:0005975 (47.9%) "GO:0047736 (50.7%) GO:0016787 (1.4%)" carbohydrate metabolic process (47.9%) "cellobiose epimerase activity (50.7%) hydrolase activity (1.4%)" "IPR010819 (25.7%) IPR028584 (25.7%) IPR008928 (24.3%)" "N-acylglucosamine 2-epimerase/Cellobiose 2-epimerase (25.7%) Cellobiose 2-epimerase (25.7%) Six-hairpin glycosidase superfamily (24.3%)" LLLQSGLK root "3.5.4.12 (81.3%) 1.1.1.193 (2.3%) 2.4.2.- (2.3%)" "dCMP deaminase (81.3%) 5-amino-6-(5-phosphoribosylamino)uracil reductase (2.3%) Pentosyltransferases (2.3%)" "GO:0009165 (10.1%) GO:0006220 (8.9%) GO:0046677 (0.7%)" "GO:0005737 (17.3%) GO:0005886 (1.7%) GO:0016020 (1.2%)" "GO:0008270 (16.8%) GO:0004132 (16.6%) GO:0022857 (1.1%)" "nucleotide biosynthetic process (10.1%) pyrimidine nucleotide metabolic process (8.9%) response to antibiotic (0.7%)" "cytoplasm (17.3%) plasma membrane (1.7%) membrane (1.2%)" "zinc ion binding (16.8%) dCMP deaminase activity (16.6%) transmembrane transporter activity (1.1%)" "IPR002125 (12.7%) IPR016193 (12.6%) IPR015517 (12.4%)" "Cytidine and deoxycytidylate deaminase domain (12.7%) Cytidine deaminase-like (12.6%) Deoxycytidylate deaminase-related (12.4%)" SLALYNVQSLPTFFLLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (25%) GO:0030313 (25%) "GO:0016209 (25%) GO:0016491 (25%)" cytochrome complex assembly (25%) cell envelope (25%) "antioxidant activity (25%) oxidoreductase activity (25%)" "IPR000866 (25%) IPR025380 (25%) IPR036249 (25%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (25%) Domain of unknown function DUF4369 (25%) Thioredoxin-like superfamily (25%)" TNMDLTLKPGNDFYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" KNSFYELVLDNTPFYGEMGGQVGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" FGYTTLVQCVLETGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (32.2%) GO:0009982 (1.1%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (32.2%) pseudouridine synthase activity (1.1%)" "IPR006145 (14.7%) IPR006224 (14.7%) IPR006225 (14.7%)" "Pseudouridine synthase, RsuA/RluA-like (14.7%) Pseudouridine synthase, RluA-like, conserved site (14.7%) Pseudouridine synthase, RluC/RluD (14.7%)" VLPHNFNELCDAAVHYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.8%) IPR050220 (20.8%) IPR013758 (19.7%)" "DNA topoisomerase, type IIA, domain A (20.8%) Type II DNA Topoisomerases (20.8%) DNA topoisomerase, type IIA, domain A, alpha-beta (19.7%)" VLGMYDK root "2.7.7.65 (50%) 3.1.13.1 (50%)" "diguanylate cyclase (50%) exoribonuclease II (50%)" "GO:0006635 (2.1%) GO:0055085 (1.6%) GO:0015833 (1.1%)" "GO:0005886 (8.5%) GO:0005777 (2.1%) GO:0005788 (0.5%)" "GO:0010181 (15.4%) GO:0009055 (14.4%) GO:0016491 (14.4%)" "fatty acid beta-oxidation (2.1%) transmembrane transport (1.6%) peptide transport (1.1%)" "plasma membrane (8.5%) peroxisome (2.1%) endoplasmic reticulum lumen (0.5%)" "FMN binding (15.4%) electron transfer activity (14.4%) oxidoreductase activity (14.4%)" "IPR001279 (11%) IPR008254 (11%) IPR045761 (11%)" "Metallo-beta-lactamase (11%) Flavodoxin/nitric oxide synthase (11%) ODP domain (11%)" NLLSYFK root "2.4.-.- (9.4%) 2.7.7.7 (8.2%) 3.1.-.- (7.1%)" "Glycosyltransferases (9.4%) DNA-directed DNA polymerase (8.2%) Acting on ester bonds (7.1%)" "GO:0045944 (1%) GO:0046854 (1%) GO:0048015 (1%)" "GO:0016020 (7.9%) GO:0005737 (3%) GO:0005634 (2.7%)" "GO:0003677 (4.5%) GO:0005524 (4.4%) GO:0016787 (4%)" "positive regulation of transcription by RNA polymerase II (1%) phosphatidylinositol phosphate biosynthetic process (1%) phosphatidylinositol-mediated signaling (1%)" "membrane (7.9%) cytoplasm (3%) nucleus (2.7%)" "DNA binding (4.5%) ATP binding (4.4%) hydrolase activity (4%)" "IPR027417 (2.9%) IPR029044 (2.2%) IPR001173 (1.9%)" "P-loop containing nucleoside triphosphate hydrolase (2.9%) Nucleotide-diphospho-sugar transferases (2.2%) Glycosyltransferase 2-like (1.9%)" LPFFEYGLLWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016020 (63.2%) "GO:0016757 (26.3%) GO:0016740 (10.5%)" membrane (63.2%) "glycosyltransferase activity (26.3%) transferase activity (10.5%)" "IPR050834 (51%) IPR029044 (49%)" "Glycosyltransferase 2 family enzymes (51%) Nucleotide-diphospho-sugar transferases (49%)" FEVSSEDLDFSTSAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006271 (17.1%) "GO:0009360 (17.1%) GO:0005737 (14.5%)" "GO:0003677 (17.1%) GO:0003887 (17.1%) GO:0008408 (17.1%)" DNA strand elongation involved in DNA replication (17.1%) "DNA polymerase III complex (17.1%) cytoplasm (14.5%)" "DNA binding (17.1%) DNA-directed DNA polymerase activity (17.1%) 3'-5' exonuclease activity (17.1%)" "IPR001001 (20.3%) IPR022634 (20.3%) IPR022635 (20.3%)" "DNA polymerase III, beta sliding clamp (20.3%) DNA polymerase III, beta sliding clamp, N-terminal (20.3%) DNA polymerase III, beta sliding clamp, C-terminal (20.3%)" LTVENQALGGMSSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR013830 (26.7%) IPR036514 (26.7%) IPR037459 (26.7%)" "SGNH hydrolase-type esterase domain (26.7%) SGNH hydrolase superfamily (26.7%) Rhamnogalacturonan acetylesterase RhgT-like (26.7%)" LCSSFLADKVSSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (47.6%) GO:0016020 (4.8%)" GO:0022857 (47.6%) "plasma membrane (47.6%) membrane (4.8%)" transmembrane transporter activity (47.6%) "IPR011701 (34.5%) IPR050375 (34.5%) IPR036259 (31%)" "Major facilitator superfamily (34.5%) Major Facilitator Superfamily TsgA-like (34.5%) MFS transporter superfamily (31%)" LSMELLDR root "3.1.3.62 (16.7%) 3.1.3.80 (16.7%) 3.2.1.- (16.7%)" "multiple inositol-polyphosphate phosphatase (16.7%) 2,3-bisphosphoglycerate 3-phosphatase (16.7%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (16.7%)" "GO:0005975 (19.8%) GO:0000160 (0.9%) GO:0000716 (0.9%)" "GO:0016020 (3.8%) GO:0005737 (1.9%) GO:0005634 (0.9%)" "GO:0008422 (17%) GO:0016787 (7.5%) GO:0005524 (3.8%)" "carbohydrate metabolic process (19.8%) phosphorelay signal transduction system (0.9%) transcription-coupled nucleotide-excision repair, DNA damage recognition (0.9%)" "membrane (3.8%) cytoplasm (1.9%) nucleus (0.9%)" "beta-glucosidase activity (17%) hydrolase activity (7.5%) ATP binding (3.8%)" "IPR001764 (7%) IPR002772 (7%) IPR017853 (7%)" "Glycoside hydrolase, family 3, N-terminal (7%) Glycoside hydrolase family 3 C-terminal domain (7%) Glycoside hydrolase superfamily (7%)" AEMNGVVNLSVLDGWWVEGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (87.5%) 2.4.1.8 (12.5%)" "glycogen phosphorylase (87.5%) maltose phosphorylase (12.5%)" GO:0005975 (33%) "GO:0008184 (33%) GO:0030170 (33%) GO:0050082 (0.9%)" carbohydrate metabolic process (33%) "glycogen phosphorylase activity (33%) pyridoxal phosphate binding (33%) maltose phosphorylase activity (0.9%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" LYSVADR root "6.3.4.14 (26.2%) 2.8.1.- (19%) 2.7.11.1 (9.5%)" "biotin carboxylase (26.2%) Sulfurtransferases (19%) non-specific serine/threonine protein kinase (9.5%)" "GO:0005975 (15.5%) GO:0000028 (1.7%) GO:0000462 (1.7%)" "GO:0005737 (2.6%) GO:0005886 (2.4%) GO:0032040 (1.7%)" "GO:0003824 (9.9%) GO:0016787 (6.6%) GO:0005524 (3.5%)" "carbohydrate metabolic process (15.5%) ribosomal small subunit assembly (1.7%) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (1.7%)" "cytoplasm (2.6%) plasma membrane (2.4%) small-subunit processome (1.7%)" "catalytic activity (9.9%) hydrolase activity (6.6%) ATP binding (3.5%)" "IPR004300 (10%) IPR052046 (10%) IPR011330 (9.7%)" "Glycoside hydrolase family 57, N-terminal domain (10%) Glycosyl hydrolase family 57 (10%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (9.7%)" NLWVTTLGDELR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.1.3.1 (100%) alkaline phosphatase (100%) GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.7%) IPR026263 (33.1%) IPR017850 (32.2%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.7%) Alkaline phosphatase, prokaryotic (33.1%) Alkaline-phosphatase-like, core domain superfamily (32.2%)" TLREELSAAYHAGANYGLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (32%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (32%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" CAFEGVYDLFALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.6.5 (100%) GTP diphosphokinase (100%) GO:0015969 (42.3%) GO:0005886 (42.3%) "GO:0016787 (9.9%) GO:0008728 (2.8%) GO:0016301 (2.8%)" guanosine tetraphosphate metabolic process (42.3%) plasma membrane (42.3%) "hydrolase activity (9.9%) GTP diphosphokinase activity (2.8%) kinase activity (2.8%)" "IPR002912 (10.2%) IPR004095 (10.2%) IPR007685 (10.2%)" "ACT domain (10.2%) TGS (10.2%) RelA/SpoT (10.2%)" MNLFTYLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) IPR019847 (100%) Gliding motility associated protein GldN (100%) GSFSHCVYSDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (1%) "GO:0000155 (24.7%) GO:0003700 (24.7%) GO:0005524 (24.7%)" membrane (1%) "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (24.7%) ATP binding (24.7%)" "IPR001789 (7.5%) IPR003594 (7.5%) IPR003661 (7.5%)" "Signal transduction response regulator, receiver domain (7.5%) Histidine kinase/HSP90-like ATPase domain (7.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.5%)" GLQGPEDTKYR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.7%) IPR044993 (9.7%) IPR017853 (9.2%)" "Glycoside hydrolase, family 3, N-terminal (9.7%) Beta-D-xylosidase (9.7%) Glycoside hydrolase superfamily (9.2%)" PHYAGLGASNTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (63.6%) IPR008160 (36.4%)" "Domain of unknown function DUF4988 (63.6%) Collagen triple helix repeat (36.4%)" LNLLPAVDEEVK Pseudomonadati Bacteria Pseudomonadati "GO:0016491 (33.3%) GO:0046872 (33.3%) GO:0051287 (33.3%)" "oxidoreductase activity (33.3%) metal ion binding (33.3%) NAD binding (33.3%)" IPR005255 (100%) PdxA family (100%) LFWSGSDR root IPR013783 (100%) Immunoglobulin-like fold (100%) TELVTLK root "5.1.3.3 (30.3%) 3.1.-.- (8.1%) 2.7.13.3 (6.1%)" "aldose 1-epimerase (30.3%) Acting on ester bonds (8.1%) histidine kinase (6.1%)" "GO:0007059 (7.1%) GO:0051301 (7.1%) GO:0006313 (6.9%)" "GO:0005737 (10.1%) GO:0005886 (2.5%) GO:0016020 (2%)" "GO:0003677 (7.9%) GO:0009037 (6.9%) GO:0005524 (2%)" "chromosome segregation (7.1%) cell division (7.1%) DNA transposition (6.9%)" "cytoplasm (10.1%) plasma membrane (2.5%) membrane (2%)" "DNA binding (7.9%) tyrosine-based site-specific recombinase activity (6.9%) ATP binding (2%)" "IPR002104 (4.4%) IPR004107 (4.4%) IPR010998 (4.4%)" "Integrase, catalytic domain (4.4%) Integrase, SAM-like, N-terminal (4.4%) Integrase/recombinase, N-terminal (4.4%)" ALCGLSMGGGHSFDLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (69.2%) GO:0016787 (30.8%)" "acyltransferase activity, transferring groups other than amino-acyl groups (69.2%) hydrolase activity (30.8%)" "IPR000801 (21.2%) IPR050583 (21.2%) IPR013783 (19.2%)" "Esterase-like (21.2%) Mycobacterial A85 antigen (21.2%) Immunoglobulin-like fold (19.2%)" KTAEDYLGQEVTDAVLTVPAYFSDSQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (1.4%) "GO:0005524 (33.1%) GO:0140662 (33.1%) GO:0051082 (32.5%)" cytoplasm (1.4%) "ATP binding (33.1%) ATP-dependent protein folding chaperone (33.1%) unfolded protein binding (32.5%)" "IPR013126 (16.8%) IPR018181 (16.8%) IPR043129 (16.8%)" "Heat shock protein 70 family (16.8%) Heat shock protein 70, conserved site (16.8%) ATPase, nucleotide binding domain (16.8%)" DYTLNLDAEAEETTPVYYPVSAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (48.4%) "GO:0004553 (48.4%) GO:0016787 (3.2%)" carbohydrate metabolic process (48.4%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.4%) hydrolase activity (3.2%)" "IPR046780 (22.9%) IPR032291 (20.5%) IPR050727 (20.5%)" "Atrophied bacterial Ig domain (22.9%) Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (20.5%) Glycosyl hydrolase 43 family arabinanases (20.5%)" LNTYALDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (40.9%) "GO:0052689 (40.9%) GO:0004557 (18.2%)" cell outer membrane (40.9%) "carboxylic ester hydrolase activity (40.9%) alpha-galactosidase activity (18.2%)" "IPR032812 (26.5%) IPR044060 (26.5%) IPR011050 (23.5%)" "SbsA, Ig-like domain (26.5%) Bacterial repeat domain (26.5%) Pectin lyase fold/virulence factor (23.5%)" CLSLGLDLTK Bacteria Bacteria 1.4.3.16 (100%) L-aspartate oxidase (100%) "GO:0034628 (33.5%) GO:0006508 (0.1%)" "GO:0005737 (31.8%) GO:0016020 (0.6%)" "GO:0008734 (33.5%) GO:0000166 (0.4%) GO:0016491 (0.1%)" "'de novo' NAD+ biosynthetic process from L-aspartate (33.5%) proteolysis (0.1%)" "cytoplasm (31.8%) membrane (0.6%)" "L-aspartate oxidase activity (33.5%) nucleotide binding (0.4%) oxidoreductase activity (0.1%)" "IPR003953 (16.8%) IPR005288 (16.8%) IPR027477 (16.7%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (16.8%) L-aspartate oxidase (16.8%) Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily (16.7%)" SGNLGGLSSYTTLNTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (2.6%) GO:0009279 (94.9%) GO:0015344 (2.6%) siderophore transmembrane transport (2.6%) cell outer membrane (94.9%) siderophore uptake transmembrane transporter activity (2.6%) "IPR039426 (14.9%) IPR000531 (14.5%) IPR012910 (14.5%)" "TonB-dependent receptor-like (14.9%) TonB-dependent receptor-like, beta-barrel (14.5%) TonB-dependent receptor, plug domain (14.5%)" TYAEDKNALTLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" DFLSTLSNLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.97.1.4 (100%) [formate-C-acetyltransferase]-activating enzyme (100%) GO:0005737 (21.2%) "GO:0043365 (21.2%) GO:0046872 (21.2%) GO:0051539 (21.2%)" cytoplasm (21.2%) "[formate-C-acetyltransferase]-activating enzyme activity (21.2%) metal ion binding (21.2%) 4 iron, 4 sulfur cluster binding (21.2%)" "IPR001989 (19%) IPR007197 (19%) IPR012838 (19%)" "Radical-activating enzyme, conserved site (19%) Radical SAM (19%) Pyruvate formate-lyase 1 activating enzyme (19%)" GVDFKLEGETNDYFAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (13.8%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (13.8%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" LLHLEEELHK root "GO:0034605 (19%) GO:0042026 (15.6%) GO:0006508 (2.3%)" "GO:0005737 (19.1%) GO:0009507 (0.3%) GO:0009532 (0.3%)" "GO:0005524 (19.8%) GO:0016887 (19.8%) GO:0008233 (2.3%)" "cellular response to heat (19%) protein refolding (15.6%) proteolysis (2.3%)" "cytoplasm (19.1%) chloroplast (0.3%) plastid stroma (0.3%)" "ATP binding (19.8%) ATP hydrolysis activity (19.8%) peptidase activity (2.3%)" "IPR003959 (8.6%) IPR050130 (8.6%) IPR003593 (8.6%)" "ATPase, AAA-type, core (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) AAA+ ATPase domain (8.6%)" YDLVPGEK Bacteria Bacteria "2.7.1.33 (99.6%) 3.1.1.41 (0.4%)" "pantothenate kinase (99.6%) cephalosporin-C deacetylase (0.4%)" GO:0015937 (24.3%) "GO:0005737 (24.3%) GO:0009279 (2.7%)" "GO:0004594 (24.3%) GO:0005524 (24.3%) GO:0016301 (0.1%)" coenzyme A biosynthetic process (24.3%) "cytoplasm (24.3%) cell outer membrane (2.7%)" "pantothenate kinase activity (24.3%) ATP binding (24.3%) kinase activity (0.1%)" "IPR004566 (29.3%) IPR006083 (29.3%) IPR027417 (29.3%)" "Pantothenate kinase (29.3%) Phosphoribulokinase/uridine kinase (29.3%) P-loop containing nucleoside triphosphate hydrolase (29.3%)" EMNVPLLAQLPLVQSLCEGGDDGAPAATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016226 (16.7%) "GO:0005524 (16.7%) GO:0016887 (16.7%) GO:0046872 (16.7%)" iron-sulfur cluster assembly (16.7%) "ATP binding (16.7%) ATP hydrolysis activity (16.7%) metal ion binding (16.7%)" "IPR019591 (20.5%) IPR033756 (20.5%) IPR044304 (20.5%)" "Mrp/NBP35 ATP-binding protein (20.5%) Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 (20.5%) Iron-sulfur protein NUBPL-like (20.5%)" LTLEPLSSGSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR032167 (50%)" "Immunoglobulin-like fold (50%) Protein of unknown function DUF5003 (50%)" ELGADVTVFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000162 (33.3%) GO:0005829 (33.3%) GO:0004049 (33.3%) L-tryptophan biosynthetic process (33.3%) cytosol (33.3%) anthranilate synthase activity (33.3%) "IPR006221 (25%) IPR017926 (25%) IPR029062 (25%)" "Anthranilate synthase/para-aminobenzoate synthase like domain (25%) Glutamine amidotransferase (25%) Class I glutamine amidotransferase-like (25%)" NHAVLAPLDPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" AADGETDLYWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.3%) IPR002469 (25.3%) IPR050278 (25.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.3%) Dipeptidylpeptidase IV, N-terminal domain (25.3%) Serine protease S9B/DPPIV (25.3%)" WQAEFFNK root 5.3.1.13 (100%) arabinose-5-phosphate isomerase (100%) "GO:0005975 (22.3%) GO:1901135 (22.3%) GO:0006508 (1.8%)" GO:0005737 (1.8%) "GO:0019146 (22.3%) GO:0097367 (22.3%) GO:0008234 (1.8%)" "carbohydrate metabolic process (22.3%) carbohydrate derivative metabolic process (22.3%) proteolysis (1.8%)" cytoplasm (1.8%) "arabinose-5-phosphate isomerase activity (22.3%) carbohydrate derivative binding (22.3%) cysteine-type peptidase activity (1.8%)" "IPR000644 (13.3%) IPR001347 (13.3%) IPR004800 (13.3%)" "CBS domain (13.3%) SIS domain (13.3%) Phosphosugar isomerase, KdsD/KpsF-type (13.3%)" GLDASVPGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.5%) IPR051802 (19.5%) IPR001599 (19%)" "Macroglobulin domain (19.5%) Alpha-2-macroglobulin-like (19.5%) Alpha-2-macroglobulin (19%)" RSDMTGALSSVNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "Carboxypeptidase-like, regulatory domain superfamily (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" VYLESTDDEEHAEDSSHLLPALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.3%) "GO:0003677 (25.3%) GO:0003917 (25.3%) GO:0046872 (24.1%)" DNA topological change (25.3%) "DNA binding (25.3%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.3%) metal ion binding (24.1%)" "IPR000380 (7.6%) IPR003602 (7.6%) IPR013497 (7.6%)" "DNA topoisomerase, type IA (7.6%) DNA topoisomerase, type IA, DNA-binding domain (7.6%) DNA topoisomerase, type IA, central (7.6%)" DGNYTLTFTSEDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032167 (61.5%) IPR013783 (38.5%)" "Protein of unknown function DUF5003 (61.5%) Immunoglobulin-like fold (38.5%)" PELQTAQTQYNPNYPQYMVDVDVAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (23.9%) GO:0005886 (25.8%) "GO:0042910 (25.8%) GO:0015562 (24.5%)" response to toxic substance (23.9%) plasma membrane (25.8%) "xenobiotic transmembrane transporter activity (25.8%) efflux transmembrane transporter activity (24.5%)" "IPR001036 (34.2%) IPR027463 (33.3%) IPR004764 (32.5%)" "Acriflavin resistance protein (34.2%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%) Multidrug resistance protein MdtF-like (32.5%)" FLNGTLDLHVQLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.3.1.50 (69.4%) 2.3.1.47 (30.6%)" "serine C-palmitoyltransferase (69.4%) 8-amino-7-oxononanoate synthase (30.6%)" GO:0030148 (7.5%) GO:0016020 (7.5%) "GO:0030170 (40.1%) GO:0016740 (19.2%) GO:0008483 (14.6%)" sphingolipid biosynthetic process (7.5%) membrane (7.5%) "pyridoxal phosphate binding (40.1%) transferase activity (19.2%) transaminase activity (14.6%)" "IPR004839 (16.8%) IPR050087 (16.8%) IPR015421 (16.7%)" "Aminotransferase, class I/classII, large domain (16.8%) 8-amino-7-oxononanoate synthase class-II (16.8%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" SPLEEWVDYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) GLNKGDEFTAYVPAFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR032317 (51.2%) IPR011053 (48.8%)" "Unknown (51.2%) Single hybrid motif (48.8%)" AEHTNQLYTMLQHFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" DGAVLVFSYLGYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.2%) IPR012910 (13.2%) IPR037066 (13.2%)" "Carboxypeptidase-like, regulatory domain superfamily (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent receptor, plug domain superfamily (13.2%)" LGEVAGVNLVTFQDMVDALQKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.6%) IPR032466 (47.4%)" "Uronate isomerase (52.6%) Metal-dependent hydrolase (47.4%)" ALFPNTYGMPVLTFEAGEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.6%) GO:0006002 (13.8%)" GO:0005829 (14.6%) "GO:0003872 (14.6%) GO:0046872 (14.6%) GO:0005524 (13.8%)" "response to glucose (14.6%) fructose 6-phosphate metabolic process (13.8%)" cytosol (14.6%) "6-phosphofructokinase activity (14.6%) metal ion binding (14.6%) ATP binding (13.8%)" "IPR000023 (26%) IPR011183 (24.7%) IPR022953 (24.7%)" "Phosphofructokinase domain (26%) Pyrophosphate-dependent phosphofructokinase PfpB (24.7%) ATP-dependent 6-phosphofructokinase (24.7%)" NLDMMSASEYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QEVTQTFYLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LVLTAEYYYSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (2.2%) GO:0009279 (95.7%) GO:0015344 (2.2%) siderophore transmembrane transport (2.2%) cell outer membrane (95.7%) siderophore uptake transmembrane transporter activity (2.2%) "IPR000531 (15.1%) IPR039426 (15.1%) IPR023996 (14.4%)" "TonB-dependent receptor-like, beta-barrel (15.1%) TonB-dependent receptor-like (15.1%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" SLVNDMNLAYLSGYYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" YNWESVSVEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TEQLPGDTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (19.4%) GO:0031564 (19.4%)" GO:0005829 (19.4%) "GO:0003700 (19.4%) GO:0003723 (19.4%) GO:0003746 (3.2%)" "DNA-templated transcription termination (19.4%) transcription antitermination (19.4%)" cytosol (19.4%) "DNA-binding transcription factor activity (19.4%) RNA binding (19.4%) translation elongation factor activity (3.2%)" "IPR003029 (12%) IPR010213 (12%) IPR013735 (12%)" "S1 domain (12%) Transcription factor NusA (12%) Transcription factor NusA, N-terminal (12%)" TATGTGALPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0017038 (50%) GO:0005886 (50%) protein import (50%) plasma membrane (50%) "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" LFAETVAALFSANGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.8%) IPR016066 (14.8%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.8%) Alpha-D-phosphohexomutase, conserved site (14.8%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" WGNLYYASDYFEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR004514 (10.6%) IPR020058 (10.6%) IPR020059 (10.6%)" "Glutamine-tRNA synthetase (10.6%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.6%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain (10.6%)" ASMSHPTDLYLVTPGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.5%) IPR001375 (20.9%) IPR011042 (19.8%)" "WD40-like beta-propeller (21.5%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20.9%) Six-bladed beta-propeller, TolB-like (19.8%)" DVDGFHPVNVGR Bacteria Bacteria "3.5.4.9 (50.1%) 1.5.1.5 (49.9%)" "methenyltetrahydrofolate cyclohydrolase (50.1%) methylenetetrahydrofolate dehydrogenase (NADP(+)) (49.9%)" "GO:0035999 (14.7%) GO:0006164 (13.8%) GO:0009086 (13.8%)" GO:0005829 (14.6%) "GO:0004477 (14.7%) GO:0004488 (14.7%)" "tetrahydrofolate interconversion (14.7%) purine nucleotide biosynthetic process (13.8%) methionine biosynthetic process (13.8%)" cytosol (14.6%) "methenyltetrahydrofolate cyclohydrolase activity (14.7%) methylenetetrahydrofolate dehydrogenase (NADP+) activity (14.7%)" "IPR000672 (17%) IPR020630 (17%) IPR020631 (17%)" "Tetrahydrofolate dehydrogenase/cyclohydrolase (17%) Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (17%) Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (17%)" EHFNEQPPAVPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (7.1%) IPR006101 (7.1%) IPR006102 (7.1%)" "Beta galactosidase small chain/ domain 5 (7.1%) Glycoside hydrolase, family 2 (7.1%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.1%)" SSAADVYAYLLSELEDVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" HFAQVGEEMTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.11 (100%) 3-methyl-2-oxobutanoate hydroxymethyltransferase (100%) "GO:0015940 (19.7%) GO:0032259 (10.6%)" GO:0005737 (19.7%) "GO:0000287 (19.7%) GO:0003864 (19.7%) GO:0008168 (10.6%)" "pantothenate biosynthetic process (19.7%) methylation (10.6%)" cytoplasm (19.7%) "magnesium ion binding (19.7%) 3-methyl-2-oxobutanoate hydroxymethyltransferase activity (19.7%) methyltransferase activity (10.6%)" "IPR003700 (33.3%) IPR015813 (33.3%) IPR040442 (33.3%)" "Ketopantoate hydroxymethyltransferase (33.3%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (33.3%) Pyruvate kinase-like domain superfamily (33.3%)" SFGGAQVSR root "1.3.5.1 (98.9%) 1.3.5.4 (1%) 1.-.-.- (0.1%)" "succinate dehydrogenase (98.9%) Transferred entry: 1.3.5.1 (1%) Oxidoreductases (0.1%)" "GO:0009061 (19.3%) GO:0006633 (0%)" "GO:0005886 (19.3%) GO:0009317 (0%)" "GO:0009055 (19.3%) GO:0050660 (19.3%) GO:0000104 (14.9%)" "anaerobic respiration (19.3%) fatty acid biosynthetic process (0%)" "plasma membrane (19.3%) acetyl-CoA carboxylase complex (0%)" "electron transfer activity (19.3%) flavin adenine dinucleotide binding (19.3%) succinate dehydrogenase activity (14.9%)" "IPR003953 (14.4%) IPR030664 (14.4%) IPR036188 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) FAD/NAD(P)-binding domain superfamily (14.4%)" RLTQEELEQGEAY Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.10.3.- (100%) With oxygen as acceptor (100%) GO:0019646 (16.7%) "GO:0005886 (16.7%) GO:0070069 (16.7%)" "GO:0009055 (16.7%) GO:0016682 (16.7%) GO:0046872 (16.7%)" aerobic electron transport chain (16.7%) "plasma membrane (16.7%) cytochrome complex (16.7%)" "electron transfer activity (16.7%) oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (16.7%) metal ion binding (16.7%)" IPR003317 (100%) Cytochrome ubiquinol oxidase subunit 2 (100%) LFGTAMNK root 3.1.1.11 (100%) pectinesterase (100%) "GO:0006633 (7.5%) GO:0044550 (7.5%) GO:0009847 (2.5%)" "GO:0005737 (7.5%) GO:0005886 (7.5%) GO:0016020 (5%)" "GO:0004312 (7.5%) GO:0004313 (7.5%) GO:0004315 (7.5%)" "fatty acid biosynthetic process (7.5%) secondary metabolite biosynthetic process (7.5%) spore germination (2.5%)" "cytoplasm (7.5%) plasma membrane (7.5%) membrane (5%)" "fatty acid synthase activity (7.5%) [acyl-carrier-protein] S-acetyltransferase activity (7.5%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (7.5%)" "IPR010106 (58.2%) IPR000873 (1.3%) IPR001031 (1.3%)" "Recombination-promoting nuclease RpnA (58.2%) AMP-dependent synthetase/ligase domain (1.3%) Thioesterase (1.3%)" FDRELHVDLPGLNER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" MQNLFNEGVLSGQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR032317 (51.2%) IPR011053 (48.8%)" "Unknown (51.2%) Single hybrid motif (48.8%)" DEHTNGLLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007121 (7.9%) IPR007641 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase, beta subunit, conserved site (7.9%) RNA polymerase Rpb2, domain 7 (7.9%)" AEGFKEMNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella LTDLVSLK root "2.7.7.49 (16.7%) 2.7.7.7 (16.7%) 3.4.24.70 (16.7%)" "RNA-directed DNA polymerase (16.7%) DNA-directed DNA polymerase (16.7%) oligopeptidase A (16.7%)" "GO:0006935 (2.6%) GO:0071973 (2.6%) GO:0005975 (1.8%)" "GO:0005886 (6.1%) GO:0016020 (6.1%) GO:0005576 (2.6%)" "GO:0005524 (4.4%) GO:0003677 (2.6%) GO:0003774 (2.6%)" "chemotaxis (2.6%) bacterial-type flagellum-dependent cell motility (2.6%) carbohydrate metabolic process (1.8%)" "plasma membrane (6.1%) membrane (6.1%) extracellular region (2.6%)" "ATP binding (4.4%) DNA binding (2.6%) cytoskeletal motor activity (2.6%)" "IPR001611 (3.1%) IPR003591 (3.1%) IPR009091 (3.1%)" "Leucine-rich repeat (3.1%) Leucine-rich repeat, typical subtype (3.1%) Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II (3.1%)" DLNGNYTLGRPWGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (44.7%) "GO:0052689 (44.7%) GO:0004557 (10.5%)" cell outer membrane (44.7%) "carboxylic ester hydrolase activity (44.7%) alpha-galactosidase activity (10.5%)" "IPR032812 (25.8%) IPR044060 (25.8%) IPR011050 (24.2%)" "SbsA, Ig-like domain (25.8%) Bacterial repeat domain (25.8%) Pectin lyase fold/virulence factor (24.2%)" SQTGTLYGTVAKGTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae MNLPQEFDTLRPWEPEDLPEVFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) AYFGGYLTGDVEASDFGEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (68.4%) "GO:0016787 (23.7%) GO:0016829 (7.9%)" carbohydrate metabolic process (68.4%) "hydrolase activity (23.7%) lyase activity (7.9%)" "IPR013783 (24.5%) IPR017853 (24.5%) IPR006047 (23.6%)" "Immunoglobulin-like fold (24.5%) Glycoside hydrolase superfamily (24.5%) Glycosyl hydrolase family 13, catalytic domain (23.6%)" KYLDYQVNLGNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003959 (25.6%) IPR051396 (25.6%) IPR027417 (25.3%)" "ATPase, AAA-type, core (25.6%) Bacterial Antiviral Defense Nuclease (25.6%) P-loop containing nucleoside triphosphate hydrolase (25.3%)" LMLSNEGDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (18.1%) IPR015883 (17.4%) IPR025705 (17.4%)" "PA14 domain (18.1%) Glycoside hydrolase family 20, catalytic domain (17.4%) Beta-hexosaminidase (17.4%)" FFADLAGVTDPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.6%) "GO:0003921 (32.6%) GO:0005524 (32.6%) GO:0016740 (2.3%)" cytosol (32.6%) "GMP synthase activity (32.6%) ATP binding (32.6%) transferase activity (2.3%)" "IPR001674 (13.1%) IPR014729 (13.1%) IPR025777 (13.1%)" "GMP synthase, C-terminal (13.1%) Rossmann-like alpha/beta/alpha sandwich fold (13.1%) GMP synthetase ATP pyrophosphatase domain (13.1%)" GMNPYLGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (50%) GO:0015134 (50%) membrane (50%) hexuronate transmembrane transporter activity (50%) "IPR011701 (25.3%) IPR020846 (25.3%) IPR050382 (25.3%)" "Major facilitator superfamily (25.3%) Major facilitator superfamily domain (25.3%) Major Facilitator Superfamily Sodium/Anion Cotransporter (25.3%)" VHLDDSDLPSAEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR019847 (100%) Gliding motility associated protein GldN (100%) SLLGEEAAQFTLVCLPAALEAHTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (83.3%) GO:0016740 (16.7%)" "glycosyltransferase activity (83.3%) transferase activity (16.7%)" "IPR000836 (50%) IPR029057 (50%)" "Phosphoribosyltransferase domain (50%) Phosphoribosyltransferase-like (50%)" YNVDGLHLDYLR root GO:0005975 (33.3%) GO:0016787 (66.7%) carbohydrate metabolic process (33.3%) hydrolase activity (66.7%) "IPR017853 (32.1%) IPR052177 (32.1%) IPR003790 (31.2%)" "Glycoside hydrolase superfamily (32.1%) Divisome-localized Glycosyl Hydrolase (32.1%) Glycosyl hydrolase-like 10 (31.2%)" FDMAFVDGDKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (32.9%) "GO:0008171 (33.5%) GO:0008757 (33.5%)" methylation (32.9%) "O-methyltransferase activity (33.5%) S-adenosylmethionine-dependent methyltransferase activity (33.5%)" "IPR002935 (33.5%) IPR050362 (33.5%) IPR029063 (32.9%)" "Class I-like SAM-dependent O-methyltransferase (33.5%) Cation-dependent O-methyltransferase (33.5%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (32.9%)" NLLNNQKPVEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (10%) GO:0016020 (80%) GO:0008233 (10%) proteolysis (10%) membrane (80%) peptidase activity (10%) "IPR006665 (25.8%) IPR036737 (25.8%) IPR050330 (25.8%)" "OmpA-like domain (25.8%) OmpA-like domain superfamily (25.8%) Bacterial Outer Membrane Structural/Functional (25.8%)" GYQVYNSTFTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) ALQYGMPPTSGLGLGLDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) "GO:0005829 (16.7%) GO:0005737 (0.1%)" "GO:0000049 (16.7%) GO:0004824 (16.7%) GO:0005524 (16.7%)" lysyl-tRNA aminoacylation (16.7%) "cytosol (16.7%) cytoplasm (0.1%)" "tRNA binding (16.7%) lysine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR004364 (12.2%) IPR006195 (12.2%) IPR018149 (12.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (12.2%) Aminoacyl-tRNA synthetase, class II (12.2%) Lysyl-tRNA synthetase, class II, C-terminal (12.1%)" LGQNSSSLSGGENQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (16.3%) IPR004602 (16.3%) IPR041102 (16.3%)" "ABC transporter-like, ATP-binding domain (16.3%) UvrABC system subunit A (16.3%) UvrA, interaction domain (16.3%)" LSYLGYK root "2.7.11.32 (19.7%) 2.7.4.27 (19.7%) 2.7.7.48 (14.5%)" "[pyruvate, phosphate dikinase] kinase (19.7%) ([Pyruvate, phosphate dikinase] phosphate) phosphotransferase (19.7%) RNA-directed RNA polymerase (14.5%)" "GO:0044718 (11%) GO:0006826 (3.3%) GO:0006508 (0.4%)" "GO:0009279 (48.3%) GO:0016020 (2%) GO:0005886 (1.3%)" "GO:0015344 (12.3%) GO:0004180 (2.2%) GO:0005524 (1.2%)" "siderophore transmembrane transport (11%) iron ion transport (3.3%) proteolysis (0.4%)" "cell outer membrane (48.3%) membrane (2%) plasma membrane (1.3%)" "siderophore uptake transmembrane transporter activity (12.3%) carboxypeptidase activity (2.2%) ATP binding (1.2%)" "IPR008969 (13.6%) IPR037066 (12.6%) IPR012910 (12.6%)" "Carboxypeptidase-like, regulatory domain superfamily (13.6%) TonB-dependent receptor, plug domain superfamily (12.6%) TonB-dependent receptor, plug domain (12.6%)" DAANNLVEVDQSGLGLGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.8%) IPR008753 (20.8%) IPR018497 (20.8%)" "Peptidase M13 (20.8%) Peptidase M13, N-terminal domain (20.8%) Peptidase M13, C-terminal domain (20.8%)" KVMDMGYSLESDYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TGSGDVNENGLLAAQNDVAYLCLPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (31.8%) GO:0046677 (31.8%)" GO:0016020 (4.5%) GO:0008800 (31.8%) "beta-lactam antibiotic catabolic process (31.8%) response to antibiotic (31.8%)" membrane (4.5%) beta-lactamase activity (31.8%) "IPR000871 (25.9%) IPR023650 (25.9%) IPR045155 (25.9%)" "Beta-lactamase, class-A (25.9%) Beta-lactamase, class-A active site (25.9%) Beta-lactamase class A, catalytic domain (25.9%)" SFNLDAQLVGHLEEGKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.7%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.7%)" "IPR004733 (20%) IPR010918 (20%) IPR016188 (20%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, C-terminal domain (20%) PurM-like, N-terminal domain (20%)" LVVADGEVEDENK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006353 (19.4%) GO:0031564 (19.4%)" GO:0005829 (19.4%) "GO:0003700 (19.4%) GO:0003723 (19.4%) GO:0003746 (3.2%)" "DNA-templated transcription termination (19.4%) transcription antitermination (19.4%)" cytosol (19.4%) "DNA-binding transcription factor activity (19.4%) RNA binding (19.4%) translation elongation factor activity (3.2%)" "IPR003029 (11.1%) IPR009019 (11.1%) IPR010213 (11.1%)" "S1 domain (11.1%) K homology domain superfamily, prokaryotic type (11.1%) Transcription factor NusA (11.1%)" QEQVEAPLNEVLAAGMLLMTGWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.8%) IPR002052 (16.8%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) DNA methylase, N-6 adenine-specific, conserved site (16.8%) THUMP domain (16.8%)" VEDVTTYPSLLGGR root "2.1.2.3 (50%) 3.5.4.10 (50%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (50%) IMP cyclohydrolase (50%)" GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (32.3%) IPR011607 (32.3%) IPR036914 (32.3%)" "Bifunctional purine biosynthesis protein PurH-like (32.3%) Methylglyoxal synthase-like domain (32.3%) Methylglyoxal synthase-like domain superfamily (32.3%)" LPDLMLYLK Bacteria Bacteria "2.7.7.65 (66.7%) 2.7.1.- (33.3%)" "diguanylate cyclase (66.7%) Phosphotransferases with an alcohol group as acceptor (33.3%)" "GO:0005737 (30.3%) GO:0005739 (3%)" "GO:0005524 (33.3%) GO:0019136 (33.3%)" "cytoplasm (30.3%) mitochondrion (3%)" "ATP binding (33.3%) deoxynucleoside kinase activity (33.3%)" "IPR002624 (19.6%) IPR027417 (19.6%) IPR031314 (19.6%)" "Deoxynucleoside kinase (19.6%) P-loop containing nucleoside triphosphate hydrolase (19.6%) Deoxynucleoside kinase domain (19.6%)" VCNANLEPVFFAYPDNEVLNELLMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) QVHVLPTWEWMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (34.2%) IPR041682 (34.2%) IPR027417 (31.6%)" "Domain of unknown function DUF4143 (34.2%) AAA domain, group 14 (34.2%) P-loop containing nucleoside triphosphate hydrolase (31.6%)" SRNDQVLVDLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 4.3.2.1 (100%) argininosuccinate lyase (100%) "GO:0042450 (33.1%) GO:0006526 (0.1%)" "GO:0005829 (33.1%) GO:0016020 (0.4%)" "GO:0004056 (33.1%) GO:0016829 (0.1%)" "L-arginine biosynthetic process via ornithine (33.1%) L-arginine biosynthetic process (0.1%)" "cytosol (33.1%) membrane (0.4%)" "argininosuccinate lyase activity (33.1%) lyase activity (0.1%)" "IPR009049 (16.7%) IPR022761 (16.7%) IPR020557 (16.7%)" "Argininosuccinate lyase (16.7%) Fumarate lyase, N-terminal (16.7%) Fumarate lyase, conserved site (16.7%)" EGFEHEFDLDALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" LSNLTLGYDFAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (17.5%) GO:0009279 (65.1%) GO:0015344 (17.5%) siderophore transmembrane transport (17.5%) cell outer membrane (65.1%) siderophore uptake transmembrane transporter activity (17.5%) "IPR012910 (13.9%) IPR023996 (13.9%) IPR023997 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent outer membrane protein, SusC/RagA (13.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.9%)" GENGAPEALSFAVPFAELRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" GSDWDFK root 3.1.3.11 (100%) fructose-bisphosphatase (100%) "GO:0006508 (23.1%) GO:0005975 (7.7%)" GO:0005737 (23.1%) "GO:0004197 (23.1%) GO:0003676 (7.7%) GO:0008270 (7.7%)" "proteolysis (23.1%) carbohydrate metabolic process (7.7%)" cytoplasm (23.1%) "cysteine-type endopeptidase activity (23.1%) nucleic acid binding (7.7%) zinc ion binding (7.7%)" "IPR007390 (17.7%) IPR056174 (17.7%) IPR057008 (17.7%)" "Sporulation stage V, protein R (17.7%) SpoVR protein-like, N-terminal (17.7%) SpoVR-like, C-terminal (17.7%)" VLYALLNPLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0008654 (33.3%) GO:0016020 (33.3%) GO:0016780 (33.3%) phospholipid biosynthetic process (33.3%) membrane (33.3%) phosphotransferase activity, for other substituted phosphate groups (33.3%) "IPR000462 (33.3%) IPR043130 (33.3%) IPR048254 (33.3%)" "CDP-alcohol phosphatidyltransferase (33.3%) CDP-alcohol phosphatidyltransferase, transmembrane domain (33.3%) CDP-alcohol phosphatidyltransferase, conserved site (33.3%)" DKYYPVFELGYGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR046111 (100%) Protein of unknown function DUF6048 (100%) GSLMGALEGLLEAQYDVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21.3%) GO:0009099 (21.3%)" "GO:0004455 (21.3%) GO:0046872 (19.1%) GO:0016853 (17%)" "isoleucine biosynthetic process (21.3%) L-valine biosynthetic process (21.3%)" "ketol-acid reductoisomerase activity (21.3%) metal ion binding (19.1%) isomerase activity (17%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" QEGFELTMHPFCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016798 (50%) GO:0030246 (50%)" "hydrolase activity, acting on glycosyl bonds (50%) carbohydrate binding (50%)" "IPR013780 (12.5%) IPR013785 (12.5%) IPR014718 (12.5%)" "Glycosyl hydrolase, all-beta (12.5%) Aldolase-type TIM barrel (12.5%) Glycoside hydrolase-type carbohydrate-binding (12.5%)" MLSLFSVK root "2.7.4.9 (50%) 2.7.7.41 (50%)" "dTMP kinase (50%) phosphatidate cytidylyltransferase (50%)" "GO:0006355 (39.3%) GO:0006227 (1.8%) GO:0006233 (1.8%)" "GO:0005789 (1.8%) GO:0005829 (1.8%)" "GO:0003677 (39.3%) GO:0016491 (5.4%) GO:0004605 (1.8%)" "regulation of DNA-templated transcription (39.3%) dUDP biosynthetic process (1.8%) dTDP biosynthetic process (1.8%)" "endoplasmic reticulum membrane (1.8%) cytosol (1.8%)" "DNA binding (39.3%) oxidoreductase activity (5.4%) phosphatidate cytidylyltransferase activity (1.8%)" "IPR012318 (22.2%) IPR014710 (21.2%) IPR018490 (20.2%)" "Crp-type HTH domain (22.2%) RmlC-like jelly roll fold (21.2%) Cyclic nucleotide-binding domain superfamily (20.2%)" NAQVATCEWEPVKCEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.7%) IPR012000 (12.7%) IPR012001 (12.7%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.7%) Thiamine pyrophosphate enzyme, central domain (12.7%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.7%)" LEWTPDYLK root "3.2.-.- (50%) 3.2.1.103 (50%)" "Glycosylases (50%) keratan-sulfate endo-1,4-beta-galactosidase (50%)" "GO:0005975 (46.9%) GO:0031505 (1%)" "GO:0005576 (1%) GO:0009277 (1%) GO:0098552 (1%)" "GO:0004553 (45.9%) GO:0008061 (1%) GO:0016757 (1%)" "carbohydrate metabolic process (46.9%) fungal-type cell wall organization (1%)" "extracellular region (1%) fungal-type cell wall (1%) side of membrane (1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (45.9%) chitin binding (1%) glycosyltransferase activity (1%)" "IPR000757 (24.5%) IPR050546 (24.5%) IPR013320 (22.9%)" "Beta-glucanase-like, N-terminal domain (24.5%) Glycosyl Hydrolase Family 16 (24.5%) Concanavalin A-like lectin/glucanase domain superfamily (22.9%)" DVNLGTNEGVYLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001478 (19.4%) IPR001940 (19.4%) IPR009003 (19.4%)" "PDZ domain (19.4%) Peptidase S1C (19.4%) Peptidase S1, PA clan (19.4%)" YLGANFVHDDERNVYQLQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" VTSYNPYPTLDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.5%) IPR012000 (12.5%) IPR012001 (12.5%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.5%) Thiamine pyrophosphate enzyme, central domain (12.5%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.5%)" FYPNTTQLLEDLAQAYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.14 (100%) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (100%) "GO:0009086 (25%) GO:0032259 (25%)" "GO:0003871 (25%) GO:0008270 (25%)" "methionine biosynthetic process (25%) methylation (25%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (25%) zinc ion binding (25%)" "IPR002629 (51.4%) IPR038071 (48.6%)" "Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (51.4%) UROD/MetE-like superfamily (48.6%)" VTEDGYYTLNRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (51.5%) GO:0016787 (48.5%) carbohydrate metabolic process (51.5%) hydrolase activity (48.5%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" LKPGLTANVTLFTQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR006143 (33.3%) IPR032317 (33.3%)" "Outer membrane efflux protein (33.3%) RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%)" TLLPQDEAGNAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (32.9%) "GO:0004475 (32.9%) GO:0005525 (31.5%) GO:0016853 (2.7%)" GDP-mannose biosynthetic process (32.9%) "mannose-1-phosphate guanylyltransferase (GTP) activity (32.9%) GTP binding (31.5%) isomerase activity (2.7%)" "IPR029044 (25.5%) IPR051161 (25.5%) IPR005835 (24.5%)" "Nucleotide-diphospho-sugar transferases (25.5%) Mannose-6-phosphate isomerase type 2 (25.5%) Nucleotidyl transferase domain (24.5%)" GLCVEGPEELLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (33.9%) "GO:0008446 (33.9%) GO:0070401 (32.3%)" 'de novo' GDP-L-fucose biosynthetic process (33.9%) "GDP-mannose 4,6-dehydratase activity (33.9%) NADP+ binding (32.3%)" "IPR006368 (33.9%) IPR016040 (33.9%) IPR036291 (32.3%)" "GDP-mannose 4,6-dehydratase (33.9%) NAD(P)-binding domain (33.9%) NAD(P)-binding domain superfamily (32.3%)" FGMLMQLPYDMDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" ENGFVPGDYSQENYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" DVLENNLLSYWLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.11 (100%) cellobiose epimerase (100%) GO:0005975 (48.3%) GO:0047736 (51.7%) carbohydrate metabolic process (48.3%) cellobiose epimerase activity (51.7%) "IPR010819 (25.9%) IPR028584 (25.9%) IPR008928 (24.1%)" "N-acylglucosamine 2-epimerase/Cellobiose 2-epimerase (25.9%) Cellobiose 2-epimerase (25.9%) Six-hairpin glycosidase superfamily (24.1%)" MVSSLMNMPVQPNK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.6%) GO:0005737 (19.3%) "GO:0003852 (20.6%) GO:0003985 (19.3%) GO:0030145 (19.3%)" L-leucine biosynthetic process (20.6%) cytoplasm (19.3%) "2-isopropylmalate synthase activity (20.6%) acetyl-CoA C-acetyltransferase activity (19.3%) manganese ion binding (19.3%)" "IPR000891 (12.6%) IPR013785 (12.6%) IPR050073 (12.6%)" "Pyruvate carboxyltransferase (12.6%) Aldolase-type TIM barrel (12.6%) 2-IPM synthase/homocitrate synthase-like (12.6%)" SGSSVNACYANVNATAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) NLFEEGELDKEVVVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011204 (100%) Virulence protein RhuM-like (100%) QGLGWDAAK Bacteria Bacteria 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0005975 (19.1%) GO:0006516 (19.1%)" GO:0005829 (19.1%) "GO:0000224 (19.1%) GO:0030246 (19.1%) GO:0016798 (4.3%)" "carbohydrate metabolic process (19.1%) glycoprotein catabolic process (19.1%)" cytosol (19.1%) "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (19.1%) carbohydrate binding (19.1%) hydrolase activity, acting on glycosyl bonds (4.3%)" "IPR005887 (16.7%) IPR008928 (16.7%) IPR012939 (16.7%)" "Glycosyl hydrolase family 92, alpha-1,2-mannosidase, putative (16.7%) Six-hairpin glycosidase superfamily (16.7%) Glycosyl hydrolase family 92 (16.7%)" RQDELDLQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KGELNALMADFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.3%) "GO:0005737 (16.3%) GO:0016020 (2.3%)" "GO:0000049 (16.3%) GO:0000287 (16.3%) GO:0004826 (16.3%)" phenylalanyl-tRNA aminoacylation (16.3%) "cytoplasm (16.3%) membrane (2.3%)" "tRNA binding (16.3%) magnesium ion binding (16.3%) phenylalanine-tRNA ligase activity (16.3%)" "IPR002319 (14.3%) IPR004188 (14.3%) IPR004529 (14.3%)" "Phenylalanyl-tRNA synthetase (14.3%) Phenylalanine-tRNA ligase, class II, N-terminal (14.3%) Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (14.3%)" WGYFPSASAAWR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (16.2%) GO:0044718 (1%)" GO:0009279 (81.9%) GO:0015344 (1%) "iron ion transport (16.2%) siderophore transmembrane transport (1%)" cell outer membrane (81.9%) siderophore uptake transmembrane transporter activity (1%) "IPR023996 (12.6%) IPR039426 (12.6%) IPR023997 (12.5%)" "TonB-dependent outer membrane protein, SusC/RagA (12.6%) TonB-dependent receptor-like (12.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.5%)" ELKEQHLMEGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri CDLSTGLGFFDHMLEQLGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.1.3.15 (50%) 4.2.1.19 (50%)" "histidinol-phosphatase (50%) imidazoleglycerol-phosphate dehydratase (50%)" GO:0000105 (20%) GO:0005737 (20%) "GO:0004401 (20%) GO:0004424 (20%) GO:0046872 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "histidinol-phosphatase activity (20%) imidazoleglycerol-phosphate dehydratase activity (20%) metal ion binding (20%)" "IPR000807 (10%) IPR005954 (10%) IPR006543 (10%)" "Imidazoleglycerol-phosphate dehydratase (10%) Histidine biosynthesis bifunctional protein, N-terminal histidinol-phosphatase domain (10%) Histidinol-phosphate phosphatase (10%)" LVNDFAPSALATWDWELNDQMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) QEGFVGTGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.99.1.3 (66.7%) 5.99.1.- (33.3%)" "Transferred entry: 5.6.2.2 (66.7%) Other isomerases (33.3%)" GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.4%) IPR050220 (20.4%) IPR013757 (19.7%)" "DNA topoisomerase, type IIA, domain A (20.4%) Type II DNA Topoisomerases (20.4%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.7%)" GQVLLDVVVDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071709 (47.7%) "GO:0009279 (50%) GO:0019867 (2.3%)" membrane assembly (47.7%) "cell outer membrane (50%) outer membrane (2.3%)" "IPR010827 (25.8%) IPR034746 (25.8%) IPR039910 (24.7%)" "POTRA domain, BamA/TamA-like (25.8%) POTRA domain (25.8%) Surface antigen D15-like (24.7%)" AGFVNLVGNPNVGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0000028 (14.5%) "GO:0005829 (14.5%) GO:0005886 (13.7%)" "GO:0005525 (14.5%) GO:0043024 (14.5%) GO:0003924 (13.8%)" ribosomal small subunit assembly (14.5%) "cytosol (14.5%) plasma membrane (13.7%)" "GTP binding (14.5%) ribosomal small subunit binding (14.5%) GTPase activity (13.8%)" "IPR006073 (12.6%) IPR005225 (12.6%) IPR005662 (12.6%)" "GTP binding domain (12.6%) Small GTP-binding domain (12.6%) GTPase Era-like (12.6%)" KDDHAGLGDWEATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.22 (97.6%) 3.2.1.- (2.4%)" "alpha-galactosidase (97.6%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.4%)" GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR050985 (12.9%) IPR013785 (12.6%)" "Glycoside hydrolase family 36 (12.9%) Alpha-glycosidase and related enzymes (12.9%) Aldolase-type TIM barrel (12.6%)" GLNFNEKDAFLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) LEAVLPAR root "2.7.13.3 (40.5%) 2.1.1.107 (20.3%) 1.3.1.76 (10.1%)" "histidine kinase (40.5%) uroporphyrinogen-III C-methyltransferase (20.3%) precorrin-2 dehydrogenase (10.1%)" "GO:0032259 (5%) GO:0009236 (4.7%) GO:0019354 (4.7%)" "GO:0016020 (7.3%) GO:0005737 (2.3%) GO:0005886 (1.4%)" "GO:0016301 (6.3%) GO:0004851 (4.7%) GO:0043115 (4.7%)" "methylation (5%) cobalamin biosynthetic process (4.7%) siroheme biosynthetic process (4.7%)" "membrane (7.3%) cytoplasm (2.3%) plasma membrane (1.4%)" "kinase activity (6.3%) uroporphyrin-III C-methyltransferase activity (4.7%) precorrin-2 dehydrogenase activity (4.7%)" "IPR003594 (3.4%) IPR036890 (3.2%) IPR005467 (3.1%)" "Histidine kinase/HSP90-like ATPase domain (3.4%) Histidine kinase/HSP90-like ATPase superfamily (3.2%) Histidine kinase domain (3.1%)" SYHYEPVPNTWGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009313 (17%) GO:0043039 (16.5%)" "GO:0004556 (17%) GO:0004812 (16.5%) GO:0005524 (16.5%)" "oligosaccharide catabolic process (17%) tRNA aminoacylation (16.5%)" "alpha-amylase activity (17%) aminoacyl-tRNA ligase activity (16.5%) ATP binding (16.5%)" "IPR006047 (26.3%) IPR012947 (25.4%) IPR017853 (24.6%)" "Glycosyl hydrolase family 13, catalytic domain (26.3%) Threonyl/alanyl tRNA synthetase, SAD (25.4%) Glycoside hydrolase superfamily (24.6%)" CTTDHLSMAGPWLK root "4.2.1.3 (88.5%) 4.2.1.- (11.4%) 4.2.1.117 (0.1%)" "aconitate hydratase (88.5%) Hydro-lyases (11.4%) 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (0.1%)" "GO:0006099 (18.6%) GO:0000002 (0.2%) GO:0016485 (0%)" "GO:0005829 (18.6%) GO:0005739 (5.8%) GO:0042645 (0.2%)" "GO:0051539 (18.6%) GO:0003994 (18.6%) GO:0046872 (18.3%)" "tricarboxylic acid cycle (18.6%) obsolete mitochondrial genome maintenance (0.2%) protein processing (0%)" "cytosol (18.6%) mitochondrion (5.8%) mitochondrial nucleoid (0.2%)" "4 iron, 4 sulfur cluster binding (18.6%) aconitate hydratase activity (18.6%) metal ion binding (18.3%)" "IPR000573 (11.3%) IPR050926 (11.3%) IPR015928 (11.2%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/IPM Isomerase (11.3%) Aconitase/3-isopropylmalate dehydratase, swivel (11.2%)" GDTALDNNYLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR004291 (50.5%) IPR052344 (49.5%)" "Transposase IS66, central domain (50.5%) Transposase-related protein (49.5%)" LHLDAQNFMGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (40.6%) GO:0089702 (9.4%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (40.6%) undecaprenyl-phosphate glucose phosphotransferase activity (9.4%)" "IPR003362 (34.8%) IPR017475 (33.7%) IPR017473 (31.5%)" "Bacterial sugar transferase (34.8%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (33.7%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (31.5%)" HYALHSGPEWAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.21 (50%) 3.2.1.37 (50%)" "beta-glucosidase (50%) xylan 1,4-beta-xylosidase (50%)" "GO:0031222 (24.9%) GO:0045493 (24.9%)" "GO:0009044 (24.9%) GO:0046556 (24.9%) GO:0008422 (0.6%)" "arabinan catabolic process (24.9%) xylan catabolic process (24.9%)" "xylan 1,4-beta-xylosidase activity (24.9%) alpha-L-arabinofuranosidase activity (24.9%) beta-glucosidase activity (0.6%)" "IPR001764 (9.6%) IPR044993 (9.6%) IPR017853 (9.4%)" "Glycoside hydrolase, family 3, N-terminal (9.6%) Beta-D-xylosidase (9.6%) Glycoside hydrolase superfamily (9.4%)" LNQYTANELEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016740 (100%) transferase activity (100%) "IPR001173 (51.9%) IPR029044 (48.1%)" "Glycosyltransferase 2-like (51.9%) Nucleotide-diphospho-sugar transferases (48.1%)" EAEGLALLTAFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" FLADFEGELPGQAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.4.1.21 (100%) S-ribosylhomocysteine lyase (100%) GO:0009372 (33.3%) "GO:0005506 (33.3%) GO:0043768 (33.3%)" quorum sensing (33.3%) "iron ion binding (33.3%) S-ribosylhomocysteine lyase activity (33.3%)" "IPR003815 (35.1%) IPR011249 (32.4%) IPR037005 (32.4%)" "S-ribosylhomocysteinase (LuxS) (35.1%) Metalloenzyme, LuxS/M16 peptidase-like (32.4%) S-ribosylhomocysteinase (LuxS) superfamily (32.4%)" LQSYVLK root "3.2.1.52 (55%) 2.7.11.1 (23.8%) 6.3.2.3 (7.5%)" "beta-N-acetylhexosaminidase (55%) non-specific serine/threonine protein kinase (23.8%) glutathione synthase (7.5%)" "GO:0005975 (7.1%) GO:0030203 (7.1%) GO:0009653 (5.3%)" "GO:0016020 (9.9%) GO:0005886 (5.3%) GO:0005737 (3.5%)" "GO:0004563 (7.1%) GO:0005524 (4.9%) GO:0005509 (4.8%)" "carbohydrate metabolic process (7.1%) glycosaminoglycan metabolic process (7.1%) anatomical structure morphogenesis (5.3%)" "membrane (9.9%) plasma membrane (5.3%) cytoplasm (3.5%)" "beta-N-acetylhexosaminidase activity (7.1%) ATP binding (4.9%) calcium ion binding (4.8%)" "IPR015883 (5.1%) IPR025705 (5.1%) IPR017853 (4.9%)" "Glycoside hydrolase family 20, catalytic domain (5.1%) Beta-hexosaminidase (5.1%) Glycoside hydrolase superfamily (4.9%)" LHLLFENSDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.7%) IPR020845 (25.7%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.7%) ANL, N-terminal domain (24.3%)" LKVPYAQNVPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" EVVAETGVAFLDLHNLAADSYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR001087 (25%) IPR013830 (25%) IPR036514 (25%)" "GDSL lipase/esterase (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" LLDGVLEK root "2.7.7.8 (50%) 6.1.1.7 (10.3%) 3.4.21.92 (6.9%)" "polyribonucleotide nucleotidyltransferase (50%) alanine--tRNA ligase (10.3%) endopeptidase Clp (6.9%)" "GO:0006396 (4.4%) GO:0006402 (4.4%) GO:0006886 (2.2%)" "GO:0005829 (5.4%) GO:0005886 (2.4%) GO:0005737 (2.2%)" "GO:0003723 (5.1%) GO:0000287 (4.9%) GO:0000175 (4.4%)" "RNA processing (4.4%) mRNA catabolic process (4.4%) intracellular protein transport (2.2%)" "cytosol (5.4%) plasma membrane (2.4%) cytoplasm (2.2%)" "RNA binding (5.1%) magnesium ion binding (4.9%) 3'-5'-RNA exonuclease activity (4.4%)" "IPR001247 (3%) IPR003029 (3%) IPR004087 (3%)" "Exoribonuclease, phosphorolytic domain 1 (3%) S1 domain (3%) K Homology domain (3%)" VDGTLQEGDVVLFLNYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" YNEHVLSVGGQLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) GDGTSDNETSDFSNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR013105 (25.4%) IPR019734 (25.4%) IPR025738 (25.4%)" "Tetratricopeptide repeat 2 (25.4%) Tetratricopeptide repeat (25.4%) Aerotolerance-related protein BatD (25.4%)" DSGHWAEYQDFMGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (100%) carbohydrate metabolic process (100%) "IPR008928 (33.3%) IPR012341 (33.3%) IPR028028 (33.3%)" "Six-hairpin glycosidase superfamily (33.3%) Six-hairpin glycosidase-like superfamily (33.3%) Protein of unknown function DUF4450 (33.3%)" LYLDDEYTGEDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (49%) GO:0016787 (51%) membrane (49%) hydrolase activity (51%) "IPR005079 (33.8%) IPR052193 (33.8%) IPR029055 (32.5%)" "Peptidase C45, hydrolase domain (33.8%) Peptidase C59 family enzymes (33.8%) Nucleophile aminohydrolases, N-terminal (32.5%)" NGVEASVLFFVPLHTWAEVQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (32.7%) "GO:0016757 (32.7%) GO:0030246 (32.7%) GO:0016740 (1.9%)" carbohydrate metabolic process (32.7%) "glycosyltransferase activity (32.7%) carbohydrate binding (32.7%) transferase activity (1.9%)" "IPR010383 (12.9%) IPR033432 (12.9%) IPR037825 (12.9%)" "Glycosyl hydrolase 94, supersandwich domain (12.9%) Glycosyl hydrolase 94, catalytic domain (12.9%) Cellobiose phosphorylase, N-terminal (12.9%)" KMTLNGSTTLDFNDGSGAQPAQLCLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TQFATVLNSDNGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) LYNPNFNYGEFALLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR018004 (60%) IPR017880 (40%)" "KilA/APSES-type HTH, DNA-binding (60%) KilA, N-terminal (40%)" NFTAKLDGTQYLFDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTVETAETSATVTFSAFTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR033427 (28.3%) IPR011050 (26.4%) IPR003961 (11.3%)" "Domain of unknown function DUF5123 (28.3%) Pectin lyase fold/virulence factor (26.4%) Fibronectin type III (11.3%)" RAEFWGEGLTGYDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" TLSVTATLSNNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (61.5%) "GO:0016787 (30.8%) GO:0016829 (7.7%)" carbohydrate metabolic process (61.5%) "hydrolase activity (30.8%) lyase activity (7.7%)" "IPR013783 (26.4%) IPR031965 (26.4%) IPR017853 (23.6%)" "Immunoglobulin-like fold (26.4%) Starch-binding module 26 (26.4%) Glycoside hydrolase superfamily (23.6%)" GRQEVGHLDLLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.6.4.13 (92%) 3.6.4.- (8%)" "RNA helicase (92%) Acting on ATP; involved in cellular and subcellular movement (8%)" GO:0005829 (10.7%) "GO:0003724 (22.3%) GO:0005524 (22.3%) GO:0016787 (22.3%)" cytosol (10.7%) "RNA helicase activity (22.3%) ATP binding (22.3%) hydrolase activity (22.3%)" "IPR000629 (10.2%) IPR001650 (10.2%) IPR005580 (10.2%)" "ATP-dependent RNA helicase DEAD-box, conserved site (10.2%) Helicase, C-terminal domain-like (10.2%) DEAD box helicase DbpA/CsdA, RNA-binding domain (10.2%)" QLNGEFNLSQLEQDMLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.8%) IPR002772 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase, family 3, N-terminal (12.8%) Glycoside hydrolase family 3 C-terminal domain (12.8%) Fibronectin type III-like domain (12.8%)" TGKPVVLLNFAGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (32.4%) GO:0005975 (1%)" GO:0042597 (33.3%) GO:0008422 (33.3%) "glucan catabolic process (32.4%) carbohydrate metabolic process (1%)" periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" TPANVLEGLGKGDVLCLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0052689 (50%) cell outer membrane (50%) carboxylic ester hydrolase activity (50%) "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" DWCDLLVVAPESAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.5 (100%) 5'-nucleotidase (100%) GO:0005737 (24%) "GO:0000166 (24%) GO:0008253 (24%) GO:0046872 (24%)" cytoplasm (24%) "nucleotide binding (24%) 5'-nucleotidase activity (24%) metal ion binding (24%)" "IPR002828 (34.2%) IPR030048 (34.2%) IPR036523 (31.5%)" "Survival protein SurE-like phosphatase/nucleotidase (34.2%) Survival protein SurE (34.2%) SurE-like phosphatase/nucleotidase superfamily (31.5%)" SEGVSASVEGGSFGSFGAQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.9%) IPR012910 (20.9%) IPR039426 (20.9%)" "TonB-dependent receptor-like, beta-barrel (20.9%) TonB-dependent receptor, plug domain (20.9%) TonB-dependent receptor-like (20.9%)" QFDYCNLDGSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FNVELDK root "2.7.13.3 (13.3%) 1.1.1.267 (6.7%) 1.8.4.11 (6.7%)" "histidine kinase (13.3%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (6.7%) peptide-methionine (S)-S-oxide reductase (6.7%)" "GO:0005975 (14.3%) GO:0006355 (1.6%) GO:0009401 (1.6%)" "GO:0016020 (4.8%) GO:0005737 (2%) GO:0005634 (1.6%)" "GO:0004553 (14.3%) GO:0003677 (2.4%) GO:0003700 (2%)" "carbohydrate metabolic process (14.3%) regulation of DNA-templated transcription (1.6%) phosphoenolpyruvate-dependent sugar phosphotransferase system (1.6%)" "membrane (4.8%) cytoplasm (2%) nucleus (1.6%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (14.3%) DNA binding (2.4%) DNA-binding transcription factor activity (2%)" "IPR006710 (7.3%) IPR051795 (7.3%) IPR041542 (7.1%)" "Glycoside hydrolase, family 43 (7.3%) Glycosyl Hydrolase Family 43 (7.3%) Beta-xylosidase, C-terminal Concanavalin A-like domain (7.1%)" ELLVAELSDNDFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) LLYDWWK root "2.3.1.311 (50%) 3.1.-.- (50%)" "tRNA carboxymethyluridine synthase (50%) Acting on ester bonds (50%)" "GO:0006508 (17.5%) GO:0002926 (5%) GO:0030968 (2.5%)" "GO:0005737 (10%) GO:0016020 (5%) GO:0000502 (2.5%)" "GO:0008236 (17.5%) GO:0016787 (5%) GO:0046872 (5%)" "proteolysis (17.5%) tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation (5%) endoplasmic reticulum unfolded protein response (2.5%)" "cytoplasm (10%) membrane (5%) proteasome complex (2.5%)" "serine-type peptidase activity (17.5%) hydrolase activity (5%) metal ion binding (5%)" "IPR029058 (18.8%) IPR050955 (18.8%) IPR001375 (7.3%)" "Alpha/Beta hydrolase fold (18.8%) Plant Biomass Hydrolyzing Esterase (18.8%) Peptidase S9, prolyl oligopeptidase, catalytic domain (7.3%)" LYGLTFK root "3.4.15.5 (81.5%) 3.4.24.- (6.4%) 3.4.24.70 (4.1%)" "peptidyl-dipeptidase Dcp (81.5%) Metalloendopeptidases (6.4%) oligopeptidase A (4.1%)" "GO:0006508 (18.4%) GO:0000271 (0.3%) GO:0006065 (0.2%)" "GO:0005829 (18.5%) GO:0016020 (0.4%) GO:0005886 (0.2%)" "GO:0046872 (18.6%) GO:0004180 (18.5%) GO:0004222 (18.5%)" "proteolysis (18.4%) polysaccharide biosynthetic process (0.3%) UDP-glucuronate biosynthetic process (0.2%)" "cytosol (18.5%) membrane (0.4%) plasma membrane (0.2%)" "metal ion binding (18.6%) carboxypeptidase activity (18.5%) metalloendopeptidase activity (18.5%)" "IPR001567 (18.7%) IPR045090 (18.7%) IPR034005 (18.5%)" "Peptidase M3A/M3B catalytic domain (18.7%) Peptidase M3A/M3B (18.7%) Peptidyl-dipeptidase DCP (18.5%)" AYSGTTYLVSAATLGGMPYASTQDPWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" TNNVQTLTFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GFAVMNLSQPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.5%) "GO:0000155 (24.5%) GO:0003700 (24.5%) GO:0043565 (24.5%)" membrane (24.5%) "phosphorelay sensor kinase activity (24.5%) DNA-binding transcription factor activity (24.5%) sequence-specific DNA binding (24.5%)" "IPR011110 (13.4%) IPR011123 (12.4%) IPR015943 (12.4%)" "Two component regulator propeller (13.4%) Two component regulator three Y (12.4%) WD40/YVTN repeat-like-containing domain superfamily (12.4%)" GTTAVMFANTANVPAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005840 (55.6%) GO:1990904 (44.4%)" "ribosome (55.6%) ribonucleoprotein complex (44.4%)" "IPR001790 (35.7%) IPR047865 (35.7%) IPR043141 (28.6%)" "Large ribosomal subunit protein uL10 (35.7%) Large ribosomal subunit protein uL10, bacteria/organella (35.7%) Large ribosomal subunit protein uL10-like domain superfamily (28.6%)" NWSGVTLWEATDAFVKDHPEALGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR001611 (20%) IPR013783 (20%) IPR024361 (20%)" "Leucine-rich repeat (20%) Immunoglobulin-like fold (20%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (20%)" QLDVLNSEDGVNFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" GGDGYFENFVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) SLVLHDMLHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (20.5%) GO:0009252 (20.5%) GO:0071555 (20.5%)" "GO:0016740 (20.5%) GO:0004180 (18.1%)" "regulation of cell shape (20.5%) peptidoglycan biosynthetic process (20.5%) cell wall organization (20.5%)" "transferase activity (20.5%) carboxypeptidase activity (18.1%)" "IPR005490 (25.8%) IPR052905 (25.8%) IPR038063 (24.2%)" "L,D-transpeptidase catalytic domain (25.8%) L,D-transpeptidase YkuD-like (25.8%) L,D-transpeptidase catalytic domain-like (24.2%)" VNADQYQYDVNDATTLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MSAEQLSTPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (31.9%) GO:0009279 (36.1%) GO:0015344 (31.9%) siderophore transmembrane transport (31.9%) cell outer membrane (36.1%) siderophore uptake transmembrane transporter activity (31.9%) "IPR036942 (51%) IPR039426 (46.9%) IPR057601 (2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (51%) TonB-dependent receptor-like (46.9%) TonB-dependent transporter Oar-like, beta-barrel domain (2%)" LFLNLGK root "3.6.4.13 (85.1%) 3.6.4.- (3.1%) 7.1.1.2 (1.2%)" "RNA helicase (85.1%) Acting on ATP; involved in cellular and subcellular movement (3.1%) NADH:ubiquinone reductase (H(+)-translocating) (1.2%)" "GO:0009409 (4.1%) GO:0042255 (3.6%) GO:0009266 (2.8%)" "GO:0005829 (10.9%) GO:0016020 (4.2%) GO:0005840 (4.2%)" "GO:0005524 (13.1%) GO:0003724 (11.4%) GO:0016787 (11.2%)" "response to cold (4.1%) ribosome assembly (3.6%) response to temperature stimulus (2.8%)" "cytosol (10.9%) membrane (4.2%) ribosome (4.2%)" "ATP binding (13.1%) RNA helicase activity (11.4%) hydrolase activity (11.2%)" "IPR027417 (8.4%) IPR005580 (7.5%) IPR001650 (7.5%)" "P-loop containing nucleoside triphosphate hydrolase (8.4%) DEAD box helicase DbpA/CsdA, RNA-binding domain (7.5%) Helicase, C-terminal domain-like (7.5%)" QAGLPLEQLMQFTGLSEENLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) SDMLDGAEPLVLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015012 (25%) GO:0050650 (25%)" GO:0016020 (25%) GO:0030158 (25%) "heparan sulfate proteoglycan biosynthetic process (25%) chondroitin sulfate proteoglycan biosynthetic process (25%)" membrane (25%) protein xylosyltransferase activity (25%) "IPR003406 (50%) IPR043538 (50%)" "Glycosyl transferase, family 14 (50%) Xylosyltransferase (50%)" YRPASEALLR Bacteria Bacteria "GO:0003723 (50%) GO:0004826 (50%)" "RNA binding (50%) phenylalanine-tRNA ligase activity (50%)" "IPR005146 (50.8%) IPR020825 (49.2%)" "B3/B4 tRNA-binding domain (50.8%) Phenylalanyl-tRNA synthetase-like, B3/B4 (49.2%)" LMGELEAR root "6.1.1.22 (88.9%) 6.1.1.14 (11.1%)" "asparagine--tRNA ligase (88.9%) glycine--tRNA ligase (11.1%)" "GO:0006421 (16.5%) GO:0006420 (2.1%) GO:0006426 (2.1%)" "GO:0005737 (15.5%) GO:0005829 (2.1%) GO:0016020 (2.1%)" "GO:0005524 (18.6%) GO:0003676 (15.5%) GO:0004816 (15.5%)" "asparaginyl-tRNA aminoacylation (16.5%) arginyl-tRNA aminoacylation (2.1%) glycyl-tRNA aminoacylation (2.1%)" "cytoplasm (15.5%) cytosol (2.1%) membrane (2.1%)" "ATP binding (18.6%) nucleic acid binding (15.5%) asparagine-tRNA ligase activity (15.5%)" "IPR004364 (12.1%) IPR004365 (11.4%) IPR004522 (11.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (12.1%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (11.4%) Asparagine-tRNA ligase (11.4%)" CLTNNEPMQTLFHTVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (20.6%) GO:0006221 (20.6%)" GO:0009347 (20.6%) "GO:0046872 (20.6%) GO:0016740 (17.5%)" "'de novo' pyrimidine nucleobase biosynthetic process (20.6%) pyrimidine nucleotide biosynthetic process (20.6%)" aspartate carbamoyltransferase complex (20.6%) "metal ion binding (20.6%) transferase activity (17.5%)" "IPR002801 (20.6%) IPR020542 (20.6%) IPR020545 (20.6%)" "Aspartate transcarbamylase regulatory subunit (20.6%) Aspartate carbamoyltransferase regulatory subunit, C-terminal (20.6%) Aspartate carbamoyltransferase regulatory subunit, N-terminal (20.6%)" ADLLEELVAHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.48 (100%) indole-3-glycerol-phosphate synthase (100%) GO:0000162 (33.3%) "GO:0004425 (33.3%) GO:0004640 (33.3%)" L-tryptophan biosynthetic process (33.3%) "indole-3-glycerol-phosphate synthase activity (33.3%) phosphoribosylanthranilate isomerase activity (33.3%)" "IPR001468 (20.5%) IPR013798 (20.5%) IPR045186 (20.5%)" "Indole-3-glycerol phosphate synthase, conserved site (20.5%) Indole-3-glycerol phosphate synthase domain (20.5%) Indole-3-glycerol phosphate synthase (20.5%)" LFLPLSR root "1.16.1.7 (39.5%) 2.7.13.3 (8.7%) 2.7.1.33 (7%)" "ferric-chelate reductase (NADH) (39.5%) histidine kinase (8.7%) pantothenate kinase (7%)" "GO:0007249 (3.7%) GO:0032715 (3.7%) GO:0032720 (3.7%)" "GO:0016020 (6%) GO:0005737 (4.8%) GO:0005886 (3.6%)" "GO:0005524 (4.6%) GO:0016747 (2.2%) GO:0003676 (2.1%)" "canonical NF-kappaB signal transduction (3.7%) negative regulation of interleukin-6 production (3.7%) negative regulation of tumor necrosis factor production (3.7%)" "membrane (6%) cytoplasm (4.8%) plasma membrane (3.6%)" "ATP binding (4.6%) acyltransferase activity, transferring groups other than amino-acyl groups (2.2%) nucleic acid binding (2.1%)" "IPR027417 (5.1%) IPR007111 (4.2%) IPR032675 (4.2%)" "P-loop containing nucleoside triphosphate hydrolase (5.1%) NACHT nucleoside triphosphatase (4.2%) Leucine-rich repeat domain superfamily (4.2%)" TYFYPMTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.8%) "GO:0046872 (25.1%) GO:0051539 (25.1%) GO:0004333 (24.2%)" tricarboxylic acid cycle (24.8%) "metal ion binding (25.1%) 4 iron, 4 sulfur cluster binding (25.1%) fumarate hydratase activity (24.2%)" "IPR004646 (18.3%) IPR051208 (18.3%) IPR004647 (18.2%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.3%) Class-I Fumarase/Tartrate Dehydratase (18.3%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.2%)" LPVDYQLCALLLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045692 (100%) Protein of unknown function DUF6057 (100%) SKFNLGAQYCYGER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YLTDNSSDLTGFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.4%) GO:0005829 (16.4%) "GO:0003677 (16.4%) GO:0004527 (16.4%) GO:0005524 (16.4%)" recombinational repair (16.4%) cytosol (16.4%) "DNA binding (16.4%) exonuclease activity (16.4%) ATP binding (16.4%)" "IPR027417 (20.5%) IPR000212 (19.9%) IPR011604 (19.9%)" "P-loop containing nucleoside triphosphate hydrolase (20.5%) DNA helicase, UvrD/REP type (19.9%) PD-(D/E)XK endonuclease-like domain superfamily (19.9%)" WFHQPMMVAQPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR018392 (34.9%) IPR028082 (32.5%) IPR036779 (32.5%)" "LysM domain (34.9%) Periplasmic binding protein-like I (32.5%) LysM domain superfamily (32.5%)" VYEFLANGFEELEGLAPVDLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (100%) cytoplasm (100%) "IPR002818 (25.2%) IPR029062 (25.2%) IPR050325 (25.2%)" "DJ-1/PfpI (25.2%) Class I glutamine amidotransferase-like (25.2%) Protein/nucleic acid deglycase (25.2%)" LKELDLPETLEEFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.9%) IPR026906 (16.9%) IPR032675 (16.9%)" "Peptidase C10, streptopain (16.9%) BspA-type LRR region (16.9%) Leucine-rich repeat domain superfamily (16.9%)" YPYPNNSDASMGGYFGDKGSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DRHDTWTSGLNVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LLHELNMGGTALGTGLNAVPGFAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.3.1.1 (100%) aspartate ammonia-lyase (100%) "GO:0006531 (25.2%) GO:0006099 (24.5%)" GO:0005829 (25.2%) GO:0008797 (25.2%) "aspartate metabolic process (25.2%) tricarboxylic acid cycle (24.5%)" cytosol (25.2%) aspartate ammonia-lyase activity (25.2%) "IPR000362 (13.5%) IPR008948 (13.5%) IPR022761 (13.5%)" "Fumarate lyase family (13.5%) L-Aspartase-like (13.5%) Fumarate lyase, N-terminal (13.5%)" VYHQDVYVLHGGEFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) GO:0006281 (25%) GO:0005829 (25%) "GO:0008967 (25%) GO:2001070 (25%)" DNA repair (25%) cytosol (25%) "phosphoglycolate phosphatase activity (25%) starch binding (25%)" "IPR002044 (10%) IPR006439 (10%) IPR006549 (10%)" "Carbohydrate binding module family 20 (10%) HAD hydrolase, subfamily IA (10%) HAD-superfamily hydrolase,subfamily IIIA (10%)" YPWNGDLALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016787 (50%) carbohydrate metabolic process (50%) hydrolase activity (50%) "IPR012878 (17.2%) IPR049046 (17.2%) IPR049174 (17.2%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like (17.2%)" LGAPSLFQPGTADFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005615 (50%) GO:0004867 (50%) extracellular space (50%) serine-type endopeptidase inhibitor activity (50%) "IPR000215 (17.2%) IPR023795 (17.2%) IPR023796 (17.2%)" "Serpin family (17.2%) Serpin, conserved site (17.2%) Serpin domain (17.2%)" LQAMNLAR root "3.5.1.108 (50%) 7.4.2.8 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) protein-secreting ATPase (50%)" "GO:0009401 (3.7%) GO:0006605 (1.9%) GO:0009245 (1.9%)" "GO:0005615 (16.7%) GO:0016020 (16.7%) GO:0005886 (14.8%)" "GO:0016301 (3.7%) GO:0046872 (3.7%) GO:0090563 (3.7%)" "phosphoenolpyruvate-dependent sugar phosphotransferase system (3.7%) protein targeting (1.9%) lipid A biosynthetic process (1.9%)" "extracellular space (16.7%) membrane (16.7%) plasma membrane (14.8%)" "kinase activity (3.7%) metal ion binding (3.7%) protein-phosphocysteine-sugar phosphotransferase activity (3.7%)" "IPR001611 (11.4%) IPR032675 (10.6%) IPR027899 (10.3%)" "Leucine-rich repeat (11.4%) Leucine-rich repeat domain superfamily (10.6%) Domain of unknown function DUF4458 (10.3%)" GGYSPAGLPSTYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales LQSLEQLR root "3.1.3.16 (29.4%) 2.8.1.7 (25.5%) 3.1.25.- (13.7%)" "protein-serine/threonine phosphatase (29.4%) cysteine desulfurase (25.5%) Site-specific endodeoxyribonucleases specific for altered bases (13.7%)" "GO:0006534 (2.6%) GO:0031122 (2.2%) GO:0042060 (2.2%)" "GO:0005737 (7.3%) GO:0005634 (4.2%) GO:0016020 (4.2%)" "GO:0005524 (4.6%) GO:0046872 (4%) GO:0004722 (3%)" "cysteine metabolic process (2.6%) cytoplasmic microtubule organization (2.2%) wound healing (2.2%)" "cytoplasm (7.3%) nucleus (4.2%) membrane (4.2%)" "ATP binding (4.6%) metal ion binding (4%) protein serine/threonine phosphatase activity (3%)" "IPR011990 (6.1%) IPR019734 (5.6%) IPR046341 (5.4%)" "Tetratricopeptide-like helical domain superfamily (6.1%) Tetratricopeptide repeat (5.6%) SET domain superfamily (5.4%)" VHEQEPVLLTYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (97.1%) GO:0016740 (2.9%) membrane (97.1%) transferase activity (2.9%) "IPR025738 (23.7%) IPR019734 (22.1%) IPR011990 (21.4%)" "Aerotolerance-related protein BatD (23.7%) Tetratricopeptide repeat (22.1%) Tetratricopeptide-like helical domain superfamily (21.4%)" VMDMGYSLESDYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VYEDKATESTSNTQFTYEELWQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" KEAQEASTLSSVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR016047 (51%) IPR011055 (49%)" "M23ase, beta-sheet core domain (51%) Duplicated hybrid motif (49%)" LKLNVVGLASSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.3 (53.5%) 2.7.2.4 (46.5%)" "homoserine dehydrogenase (53.5%) aspartate kinase (46.5%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.1%) IPR001341 (7.1%) IPR001342 (7.1%)" "Aspartate/glutamate/uridylate kinase (7.1%) Aspartate kinase (7.1%) Homoserine dehydrogenase, catalytic (7.1%)" ALFTASYK root "GO:0044718 (28.9%) GO:0005975 (1.1%) GO:0006508 (1.1%)" "GO:0009279 (28.9%) GO:0005829 (1.1%) GO:0016020 (1.1%)" "GO:0015344 (28.9%) GO:0003723 (2.2%) GO:0000224 (1.1%)" "siderophore transmembrane transport (28.9%) carbohydrate metabolic process (1.1%) proteolysis (1.1%)" "cell outer membrane (28.9%) cytosol (1.1%) membrane (1.1%)" "siderophore uptake transmembrane transporter activity (28.9%) RNA binding (2.2%) peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (1.1%)" "IPR000531 (21.3%) IPR036942 (21.3%) IPR037066 (21.3%)" "TonB-dependent receptor-like, beta-barrel (21.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (21.3%) TonB-dependent receptor, plug domain superfamily (21.3%)" VKHELAGSPYNDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (19.9%) GO:0005829 (19.9%) "GO:0004335 (19.9%) GO:0005524 (19.9%) GO:0046872 (19.9%)" galactose metabolic process (19.9%) cytosol (19.9%) "galactokinase activity (19.9%) ATP binding (19.9%) metal ion binding (19.9%)" "IPR000705 (10.2%) IPR006203 (10.2%) IPR006204 (10.2%)" "Galactokinase (10.2%) GHMP kinase, ATP-binding, conserved site (10.2%) GHMP kinase N-terminal domain (10.2%)" LLQYFVR root "4.2.3.1 (72.7%) 2.7.11.1 (6.1%) 2.7.7.41 (6.1%)" "threonine synthase (72.7%) non-specific serine/threonine protein kinase (6.1%) phosphatidate cytidylyltransferase (6.1%)" "GO:0009088 (7.4%) GO:0032259 (1.9%) GO:0006508 (1.3%)" "GO:0016020 (5.8%) GO:0005886 (2.9%) GO:0031416 (2.2%)" "GO:0004795 (7.4%) GO:0030170 (7.4%) GO:0008168 (1.6%)" "threonine biosynthetic process (7.4%) methylation (1.9%) proteolysis (1.3%)" "membrane (5.8%) plasma membrane (2.9%) NatB complex (2.2%)" "threonine synthase activity (7.4%) pyridoxal phosphate binding (7.4%) methyltransferase activity (1.6%)" "IPR000634 (5.6%) IPR001926 (5.6%) IPR004450 (5.6%)" "Serine/threonine dehydratase, pyridoxal-phosphate-binding site (5.6%) Tryptophan synthase beta chain-like, PALP domain (5.6%) Threonine synthase-like (5.6%)" EHSFTALAGMESWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" AYDFVCNGLEVGGGSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20.1%) GO:0005737 (20.1%) "GO:0004815 (20.1%) GO:0005524 (20.1%) GO:0003676 (19.7%)" aspartyl-tRNA aminoacylation (20.1%) cytoplasm (20.1%) "aspartate-tRNA ligase activity (20.1%) ATP binding (20.1%) nucleic acid binding (19.7%)" "IPR004364 (9.2%) IPR002312 (9.1%) IPR004115 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%)" NKDLVLMEDEVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0051536 (50%) GO:0016491 (48%) GO:0004355 (2%)" "iron-sulfur cluster binding (50%) oxidoreductase activity (48%) glutamate synthase (NADPH) activity (2%)" "IPR006004 (11.1%) IPR009051 (11.1%) IPR017927 (11.1%)" "Sulfide dehydrogenase subunit alpha-like (11.1%) Alpha-helical ferredoxin (11.1%) FAD-binding domain, ferredoxin reductase-type (11.1%)" FFKDNLSR root "GO:0009247 (4.9%) GO:0006269 (2.4%)" "GO:0009279 (61%) GO:0005886 (7.3%) GO:0005730 (2.4%)" "GO:0016765 (7.3%) GO:0016757 (4.9%) GO:0003899 (2.4%)" "glycolipid biosynthetic process (4.9%) DNA replication, synthesis of primer (2.4%)" "cell outer membrane (61%) plasma membrane (7.3%) nucleolus (2.4%)" "transferase activity, transferring alkyl or aryl (other than methyl) groups (7.3%) glycosyltransferase activity (4.9%) DNA-directed RNA polymerase activity (2.4%)" "IPR023996 (13%) IPR036942 (13%) IPR008969 (12.4%)" "TonB-dependent outer membrane protein, SusC/RagA (13%) TonB-dependent receptor-like, beta-barrel domain superfamily (13%) Carboxypeptidase-like, regulatory domain superfamily (12.4%)" ATSVDEQTLLDEWCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" NLPMVTENDPVGSFLPPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" KAELLDLYVYAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (32%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (32%)" "IPR033403 (11.6%) IPR000322 (11.3%) IPR025887 (11.3%)" "Domain of unknown function DUF5110 (11.6%) Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%)" SFAAHNGDPEKLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) GO:0045493 (50%) "GO:0004553 (42.9%) GO:0031176 (7.1%)" xylan catabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (42.9%) endo-1,4-beta-xylanase activity (7.1%)" "IPR001000 (33.3%) IPR044846 (33.3%) IPR017853 (28.6%)" "Glycoside hydrolase family 10 domain (33.3%) Glycoside hydrolase family 10 (33.3%) Glycoside hydrolase superfamily (28.6%)" SVFTLTTFNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0046813 (50%) GO:0009279 (50%) receptor-mediated virion attachment to host cell (50%) cell outer membrane (50%) "IPR019734 (26.3%) IPR009003 (25.3%) IPR011990 (24.2%)" "Tetratricopeptide repeat (26.3%) Peptidase S1, PA clan (25.3%) Tetratricopeptide-like helical domain superfamily (24.2%)" AQFLFPNVNLVLSTQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (50.6%) IPR023614 (49.4%)" "Phosphate-selective porin O/P (50.6%) Porin domain superfamily (49.4%)" QWADENGVTHYTHWFQPLTEGTAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.6%) IPR022147 (14.6%) IPR052725 (14.6%)" "Glutamine synthetase, N-terminal domain (14.6%) Glutamine synthetase type III N-terminal (14.6%) Glutamine Synthetase Type-3 (14.6%)" LTANGEDVLGATLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (21.6%) IPR057601 (21.6%) IPR008969 (19.6%)" "TonB-dependent receptor-like (21.6%) TonB-dependent transporter Oar-like, beta-barrel domain (21.6%) Carboxypeptidase-like, regulatory domain superfamily (19.6%)" LYDEPQYASNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006857 (33.3%) GO:0005886 (33.3%) GO:1904680 (33.3%) oligopeptide transport (33.3%) plasma membrane (33.3%) peptide transmembrane transporter activity (33.3%) "IPR000109 (16.7%) IPR005279 (16.7%) IPR018456 (16.7%)" "Proton-dependent oligopeptide transporter family (16.7%) Dipeptide/tripeptide permease (16.7%) PTR2 family proton/oligopeptide symporter, conserved site (16.7%)" VDLLDAAQMLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.7%) GO:0006526 (13.5%) GO:0006221 (12.9%)" GO:0005737 (14.7%) "GO:0004088 (14.7%) GO:0005524 (14.7%) GO:0046872 (13.5%)" "glutamine metabolic process (14.7%) L-arginine biosynthetic process (13.5%) pyrimidine nucleotide biosynthetic process (12.9%)" cytoplasm (14.7%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.7%) ATP binding (14.7%) metal ion binding (13.5%)" "IPR011607 (11%) IPR036914 (11%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (11%) Methylglyoxal synthase-like domain superfamily (11%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" NAYTFQNLANLVSAMYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) YWLNEFHFDGFR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (18.4%) GO:0005975 (2.2%)" GO:0005737 (19.9%) "GO:0003844 (19.9%) GO:0004553 (19.9%) GO:0043169 (19.9%)" "glycogen biosynthetic process (18.4%) carbohydrate metabolic process (2.2%)" cytoplasm (19.9%) "1,4-alpha-glucan branching enzyme activity (19.9%) hydrolase activity, hydrolyzing O-glycosyl compounds (19.9%) cation binding (19.9%)" "IPR006047 (13.3%) IPR004193 (12.8%) IPR006048 (12.8%)" "Glycosyl hydrolase family 13, catalytic domain (13.3%) Glycoside hydrolase, family 13, N-terminal (12.8%) Alpha-amylase/branching enzyme, C-terminal all beta (12.8%)" LKADYANAPQWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (85.7%) 2.4.1.8 (14.3%)" "glycogen phosphorylase (85.7%) maltose phosphorylase (14.3%)" GO:0005975 (33.1%) "GO:0008184 (33.1%) GO:0030170 (33.1%) GO:0050082 (0.8%)" carbohydrate metabolic process (33.1%) "glycogen phosphorylase activity (33.1%) pyridoxal phosphate binding (33.1%) maltose phosphorylase activity (0.8%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" FETNVGAGLPLLGTLNDLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.3 (52.6%) 2.7.2.4 (47.4%)" "homoserine dehydrogenase (52.6%) aspartate kinase (47.4%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.1%) IPR001341 (7.1%) IPR001342 (7.1%)" "Aspartate/glutamate/uridylate kinase (7.1%) Aspartate kinase (7.1%) Homoserine dehydrogenase, catalytic (7.1%)" RTTPSVVGFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (33.6%) GO:0140662 (33.6%) GO:0051082 (32.8%)" "ATP binding (33.6%) ATP-dependent protein folding chaperone (33.6%) unfolded protein binding (32.8%)" "IPR013126 (16.9%) IPR018181 (16.9%) IPR043129 (16.9%)" "Heat shock protein 70 family (16.9%) Heat shock protein 70, conserved site (16.9%) ATPase, nucleotide binding domain (16.9%)" VWFDPDVNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "5.99.1.- (60%) 5.99.1.3 (40%)" "Other isomerases (60%) Transferred entry: 5.6.2.2 (40%)" GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.3%) IPR050220 (20.3%) IPR013757 (19.8%)" "DNA topoisomerase, type IIA, domain A (20.3%) Type II DNA Topoisomerases (20.3%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.8%)" MQHFADLALPPVMDDDLEFYPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" FDHSSLYGNFFTPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" KGSVGDVLLNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.3 (100%) DNA 5'-3' helicase (100%) GO:0006269 (12.5%) "GO:0005829 (12.5%) GO:1990077 (12.5%)" "GO:0003677 (12.5%) GO:0003678 (12.5%) GO:0005524 (12.5%)" DNA replication, synthesis of primer (12.5%) "cytosol (12.5%) primosome complex (12.5%)" "DNA binding (12.5%) DNA helicase activity (12.5%) ATP binding (12.5%)" "IPR007692 (15.1%) IPR007693 (15.1%) IPR007694 (15.1%)" "DNA helicase, DnaB type (15.1%) DNA helicase, DnaB-like, N-terminal (15.1%) DNA helicase, DnaB-like, C-terminal (15.1%)" NPLLTAEHTPLEWR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (27%) GO:0071555 (27%)" "GO:0016758 (27%) GO:0016798 (19.1%)" "carbohydrate metabolic process (27%) cell wall organization (27%)" "hexosyltransferase activity (27%) hydrolase activity, acting on glycosyl bonds (19.1%)" "IPR007184 (33.9%) IPR028583 (33.9%) IPR023296 (32.1%)" "Mannoside phosphorylase (33.9%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (33.9%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.1%)" EGESMHTFFLPVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EVGVQFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.5%) GO:0009252 (12.5%) GO:0051301 (12.5%)" GO:0005737 (12.5%) "GO:0005524 (12.6%) GO:0000287 (12.5%) GO:0008765 (12.5%)" "regulation of cell shape (12.5%) peptidoglycan biosynthetic process (12.5%) cell division (12.5%)" cytoplasm (12.5%) "ATP binding (12.6%) magnesium ion binding (12.5%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.5%)" "IPR013221 (14.5%) IPR004101 (14.4%) IPR036565 (14.4%)" "Mur ligase, central (14.5%) Mur ligase, C-terminal (14.4%) Mur-like, catalytic domain superfamily (14.4%)" LQLTLGVK root 2.4.-.- (100%) Glycosyltransferases (100%) "GO:0009089 (1.5%) GO:0035435 (1.5%)" "GO:0016020 (50.7%) GO:0005829 (1.5%)" "GO:0016740 (22.4%) GO:0016757 (14.9%) GO:0005315 (1.5%)" "lysine biosynthetic process via diaminopimelate (1.5%) phosphate ion transmembrane transport (1.5%)" "membrane (50.7%) cytosol (1.5%)" "transferase activity (22.4%) glycosyltransferase activity (14.9%) phosphate transmembrane transporter activity (1.5%)" "IPR029044 (46.2%) IPR050834 (38.5%) IPR001173 (2.6%)" "Nucleotide-diphospho-sugar transferases (46.2%) Glycosyltransferase 2 family enzymes (38.5%) Glycosyltransferase 2-like (2.6%)" FGANAQPFYVALDNDGNPLAAAFSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (23.3%) GO:0016020 (1.7%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (23.3%) membrane (1.7%)" protein-disulfide reductase activity (25%) "IPR003834 (25.2%) IPR013766 (25.2%) IPR028250 (25.2%)" "Cytochrome C biogenesis protein, transmembrane domain (25.2%) Thioredoxin domain (25.2%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.2%)" GEEVELPKYDFQSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (35.2%) IPR027417 (33.8%) IPR018163 (31%)" "Phosphoribulokinase/uridine kinase (35.2%) P-loop containing nucleoside triphosphate hydrolase (33.8%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (31%)" ALNYYYFLDLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (51.4%) IPR011990 (48.6%)" "RagB/SusD domain (51.4%) Tetratricopeptide-like helical domain superfamily (48.6%)" AEEFVWQDMLYNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (17.2%) IPR051795 (17.2%) IPR006710 (16.7%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (17.2%) Glycosyl Hydrolase Family 43 (17.2%) Glycoside hydrolase, family 43 (16.7%)" AVVPFMTAGASLVNFSSLAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.47 (100%) glucose 1-dehydrogenase [NAD(P)(+)] (100%) GO:0016491 (100%) oxidoreductase activity (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" ESVLPVPAFNAYTNLYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) TLLSMSPSLAQVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006355 (19.6%) GO:0000160 (1%)" "GO:0005829 (19.6%) GO:0032993 (19.6%)" "GO:0000156 (19.6%) GO:0000976 (19.6%) GO:0003677 (1%)" "regulation of DNA-templated transcription (19.6%) phosphorelay signal transduction system (1%)" "cytosol (19.6%) protein-DNA complex (19.6%)" "phosphorelay response regulator activity (19.6%) transcription cis-regulatory region binding (19.6%) DNA binding (1%)" "IPR001789 (25.6%) IPR011006 (25.6%) IPR007492 (24.4%)" "Signal transduction response regulator, receiver domain (25.6%) CheY-like superfamily (25.6%) LytTR DNA-binding domain (24.4%)" YNYETNDFAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (27.1%) GO:0003700 (27.1%) GO:0043565 (27.1%)" "phosphorelay sensor kinase activity (27.1%) DNA-binding transcription factor activity (27.1%) sequence-specific DNA binding (27.1%)" "IPR001789 (6.9%) IPR003594 (6.9%) IPR003661 (6.9%)" "Signal transduction response regulator, receiver domain (6.9%) Histidine kinase/HSP90-like ATPase domain (6.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.9%)" LELHPVR root "3.4.21.102 (47.8%) 3.4.21.53 (21.5%) 2.4.1.347 (7.3%)" "C-terminal processing peptidase (47.8%) endopeptidase La (21.5%) alpha,alpha-trehalose-phosphate synthase (ADP-forming) (7.3%)" "GO:0007165 (6.7%) GO:0006508 (6.4%) GO:0000725 (2.2%)" "GO:0030288 (6.3%) GO:0031979 (5.6%) GO:0005829 (4%)" "GO:0004175 (5.8%) GO:0008236 (5.8%) GO:0005524 (5.2%)" "signal transduction (6.7%) proteolysis (6.4%) recombinational repair (2.2%)" "outer membrane-bounded periplasmic space (6.3%) plasma membrane-derived thylakoid lumen (5.6%) cytosol (4%)" "endopeptidase activity (5.8%) serine-type peptidase activity (5.8%) ATP binding (5.2%)" "IPR001478 (5.2%) IPR004447 (5.2%) IPR005151 (5.2%)" "PDZ domain (5.2%) C-terminal-processing peptidase S41A (5.2%) Tail specific protease (5.2%)" FEAVSEASK root 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.7%) IPR022147 (14.7%) IPR052725 (14.7%)" "Glutamine synthetase, N-terminal domain (14.7%) Glutamine synthetase type III N-terminal (14.7%) Glutamine Synthetase Type-3 (14.7%)" FALYENCFHEYQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR005151 (50%) IPR029045 (50%)" "Tail specific protease (50%) ClpP/crotonase-like domain superfamily (50%)" QMMADFR root "5.4.2.- (35.3%) 5.4.2.2 (35.3%) 1.8.1.9 (5.9%)" "Phosphotransferases (phosphomutases) (35.3%) phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (35.3%) thioredoxin-disulfide reductase (NADPH) (5.9%)" "GO:0005975 (23.4%) GO:0006166 (23.4%) GO:0000723 (0.3%)" "GO:0005829 (0.6%) GO:0005737 (0.3%) GO:0033202 (0.3%)" "GO:0008973 (23.4%) GO:0000287 (22.9%) GO:0005524 (0.6%)" "carbohydrate metabolic process (23.4%) purine ribonucleoside salvage (23.4%) telomere maintenance (0.3%)" "cytosol (0.6%) cytoplasm (0.3%) DNA helicase complex (0.3%)" "phosphopentomutase activity (23.4%) magnesium ion binding (22.9%) ATP binding (0.6%)" "IPR005846 (13.9%) IPR005844 (13.8%) IPR005845 (13.8%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (13.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (13.8%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (13.8%)" VLNNEFHNELADGAMFPMHAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.1.1.3 (50.9%) 2.7.2.4 (49.1%)" "homoserine dehydrogenase (50.9%) aspartate kinase (49.1%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" HNHLLTGLPDTYGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33%) GO:0005829 (33.3%) "GO:0008861 (33.3%) GO:0016829 (0.3%)" glucose metabolic process (33%) cytosol (33.3%) "formate C-acetyltransferase activity (33.3%) lyase activity (0.3%)" "IPR004184 (20.1%) IPR050244 (20.1%) IPR001150 (19.9%)" "Pyruvate formate lyase domain (20.1%) Autonomous Glycyl Radical Cofactor (20.1%) Glycine radical domain (19.9%)" VQAAGVEAPDFTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (23.9%) GO:0030313 (22%) "GO:0016209 (26.6%) GO:0016491 (26.6%) GO:0004601 (0.9%)" cytochrome complex assembly (23.9%) cell envelope (22%) "antioxidant activity (26.6%) oxidoreductase activity (26.6%) peroxidase activity (0.9%)" "IPR000866 (20.5%) IPR013766 (20.5%) IPR050553 (20.5%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.5%) Thioredoxin domain (20.5%) Thioredoxin family ResA/DsbE subfamily (20.5%)" DVLSNLLWSMLPETK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.2.19 (100%) rhamnulose-1-phosphate aldolase (100%) GO:0019323 (33.3%) GO:0005829 (33.3%) "GO:0016832 (19.4%) GO:0008994 (13.9%)" pentose catabolic process (33.3%) cytosol (33.3%) "aldehyde-lyase activity (19.4%) rhamnulose-1-phosphate aldolase activity (13.9%)" "IPR001303 (33.3%) IPR036409 (33.3%) IPR050197 (33.3%)" "Class II aldolase/adducin N-terminal (33.3%) Class II aldolase/adducin N-terminal domain superfamily (33.3%) Aldolase class II family, sugar metabolism enzymes (33.3%)" RLYGALLR root "3.1.21.3 (38.6%) 6.3.1.1 (38.6%) 6.1.1.16 (5.3%)" "type I site-specific deoxyribonuclease (38.6%) aspartate--ammonia ligase (38.6%) cysteine--tRNA ligase (5.3%)" "GO:0009307 (6.5%) GO:0070981 (6.5%) GO:0006352 (0.9%)" "GO:0005829 (8%) GO:0005737 (4.6%) GO:0016020 (3.1%)" "GO:0005524 (15.1%) GO:0003677 (7.1%) GO:0004071 (6.8%)" "DNA restriction-modification system (6.5%) L-asparagine biosynthetic process (6.5%) DNA-templated transcription initiation (0.9%)" "cytosol (8%) cytoplasm (4.6%) membrane (3.1%)" "ATP binding (15.1%) DNA binding (7.1%) aspartate-ammonia ligase activity (6.8%)" "IPR027417 (6.3%) IPR004618 (5%) IPR006195 (5%)" "P-loop containing nucleoside triphosphate hydrolase (6.3%) Aspartate--ammonia ligase (5%) Aminoacyl-tRNA synthetase, class II (5%)" EVSFGVDLNNLFNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.7%) IPR012910 (20.7%) IPR039426 (20.7%)" "TonB-dependent receptor-like, beta-barrel (20.7%) TonB-dependent receptor, plug domain (20.7%) TonB-dependent receptor-like (20.7%)" SYLDVPELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005886 (32.6%) GO:0045259 (32.6%)" "GO:0046933 (32.6%) GO:0016787 (2.3%)" "plasma membrane (32.6%) proton-transporting ATP synthase complex (32.6%)" "proton-transporting ATP synthase activity, rotational mechanism (32.6%) hydrolase activity (2.3%)" "IPR000711 (50%) IPR026015 (50%)" "ATPase, OSCP/delta subunit (50%) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily (50%)" EAVANYLK root "1.1.1.88 (30.8%) 3.2.2.21 (23.1%) 1.3.5.1 (15.4%)" "hydroxymethylglutaryl-CoA reductase (30.8%) DNA-3-methyladenine glycosylase II (23.1%) succinate dehydrogenase (15.4%)" "GO:0008360 (9.1%) GO:0009252 (8.9%) GO:0071555 (8.9%)" "GO:0005886 (8.9%) GO:0030288 (8.9%) GO:0005737 (1.9%)" "GO:0008955 (8.9%) GO:0008658 (8.7%) GO:0004180 (8.5%)" "regulation of cell shape (9.1%) peptidoglycan biosynthetic process (8.9%) cell wall organization (8.9%)" "plasma membrane (8.9%) outer membrane-bounded periplasmic space (8.9%) cytoplasm (1.9%)" "peptidoglycan glycosyltransferase activity (8.9%) penicillin binding (8.7%) carboxypeptidase activity (8.5%)" "IPR001264 (11.6%) IPR050396 (11.6%) IPR001460 (11.3%)" "Glycosyl transferase, family 51 (11.6%) Glycosyltransferase 51/Transpeptidase (11.6%) Penicillin-binding protein, transpeptidase (11.3%)" QQMTYQPVQTPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR018392 (34.8%) IPR028082 (32.6%) IPR036779 (32.6%)" "LysM domain (34.8%) Periplasmic binding protein-like I (32.6%) LysM domain superfamily (32.6%)" QVLYYSPLLPGPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.3%) "GO:0008237 (33.3%) GO:0046872 (33.3%)" proteolysis (33.3%) "metallopeptidase activity (33.3%) metal ion binding (33.3%)" "IPR008754 (33.8%) IPR023852 (33.8%) IPR024079 (32.4%)" "Peptidase M43, pregnancy-associated plasma-A (33.8%) Metalloproteinase lipoprotein, BF0631 (33.8%) Metallopeptidase, catalytic domain superfamily (32.4%)" LTTVEDLELLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.- (100%) Nucleotidyltransferases (100%) GO:0008299 (33.3%) GO:0005829 (33.3%) "GO:0050518 (17.5%) GO:0070567 (15.9%)" isoprenoid biosynthetic process (33.3%) cytosol (33.3%) "2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity (17.5%) cytidylyltransferase activity (15.9%)" "IPR018294 (33.3%) IPR029044 (33.3%) IPR034683 (33.3%)" "4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site (33.3%) Nucleotide-diphospho-sugar transferases (33.3%) Cytidylyltransferase IspD/TarI (33.3%)" WLLTDADLEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LSQVVEVEDTPSNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR005996 (25%) IPR016082 (25%) IPR018038 (25%)" "Large ribosomal subunit protein uL30, bacteria (25%) Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain (25%) Large ribosomal subunit protein uL30, conserved site (25%)" LSQLLGPVLDVYFDTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (23.2%) GO:0045259 (23.2%)" "GO:0005524 (23.2%) GO:0046933 (23.2%) GO:0016787 (7.1%)" "plasma membrane (23.2%) proton-transporting ATP synthase complex (23.2%)" "ATP binding (23.2%) proton-transporting ATP synthase activity, rotational mechanism (23.2%) hydrolase activity (7.1%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" ELKDLSGYTHGVGWCAPQQGACK Bacteria Bacteria GGWAVPAFNFNNLEQLQALLQASSTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (23.1%) GO:0006096 (7.7%) GO:0030388 (7.7%)" "GO:0008270 (30.8%) GO:0016832 (23.1%) GO:0004332 (7.7%)" "carbohydrate metabolic process (23.1%) glycolytic process (7.7%) fructose 1,6-bisphosphate metabolic process (7.7%)" "zinc ion binding (30.8%) aldehyde-lyase activity (23.1%) fructose-bisphosphate aldolase activity (7.7%)" "IPR000771 (30.8%) IPR013785 (30.8%) IPR050246 (30.8%)" "Fructose-bisphosphate aldolase, class-II (30.8%) Aldolase-type TIM barrel (30.8%) Class II Fructose-bisphosphate Aldolase (30.8%)" NHPLDAEHTDNGAFTDLFEQNQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" LSYLPDVK root "1.7.1.13 (99.6%) 1.7.1.- (0.4%)" "preQ1 synthase (99.6%) With NAD(+) or NADP(+) as acceptor (0.4%)" "GO:0008616 (24.3%) GO:0006400 (23.7%) GO:0015871 (0.4%)" "GO:0005737 (24.3%) GO:0016020 (0.4%) GO:0016324 (0.4%)" "GO:0033739 (24.3%) GO:0015297 (0.4%) GO:0090422 (0.4%)" "tRNA queuosine(34) biosynthetic process (24.3%) tRNA modification (23.7%) choline transport (0.4%)" "cytoplasm (24.3%) membrane (0.4%) apical plasma membrane (0.4%)" "preQ1 synthase activity (24.3%) antiporter activity (0.4%) thiamine pyrophosphate transmembrane transporter activity (0.4%)" "IPR016856 (24.5%) IPR029500 (24.5%) IPR043133 (24.5%)" "NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 (24.5%) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF (24.5%) GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase (24.5%)" NLPVYER root "3.4.21.89 (74.7%) 2.2.1.1 (12.3%) 2.5.1.128 (3.4%)" "signal peptidase I (74.7%) transketolase (12.3%) N(4)-bis(aminopropyl)spermidine synthase (3.4%)" "GO:0006465 (14.5%) GO:0006098 (2.3%) GO:0000724 (1.8%)" "GO:0016020 (15.3%) GO:0005634 (3%) GO:0005829 (2.9%)" "GO:0004252 (14.5%) GO:0005524 (4.2%) GO:0004802 (2.3%)" "signal peptide processing (14.5%) pentose-phosphate shunt (2.3%) double-strand break repair via homologous recombination (1.8%)" "membrane (15.3%) nucleus (3%) cytosol (2.9%)" "serine-type endopeptidase activity (14.5%) ATP binding (4.2%) transketolase activity (2.3%)" "IPR000223 (11.6%) IPR019533 (11.6%) IPR019758 (11.6%)" "Peptidase S26A, signal peptidase I (11.6%) Peptidase S26 (11.6%) Peptidase S26A, signal peptidase I, conserved site (11.6%)" SYPTQYTLDSPDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" GAVLLTTK root "7.2.1.1 (66.7%) 6.2.1.1 (33.3%)" "NADH:ubiquinone reductase (Na(+)-transporting) (66.7%) acetate--CoA ligase (33.3%)" "GO:0044718 (14.3%) GO:0006826 (5.7%) GO:0055085 (0.6%)" "GO:0009279 (53.7%) GO:0005886 (0.7%) GO:0016020 (0.6%)" "GO:0015344 (16.7%) GO:0004866 (0.6%) GO:0030246 (0.6%)" "siderophore transmembrane transport (14.3%) iron ion transport (5.7%) transmembrane transport (0.6%)" "cell outer membrane (53.7%) plasma membrane (0.7%) membrane (0.6%)" "siderophore uptake transmembrane transporter activity (16.7%) endopeptidase inhibitor activity (0.6%) carbohydrate binding (0.6%)" "IPR037066 (14%) IPR012910 (13.9%) IPR039426 (13.4%)" "TonB-dependent receptor, plug domain superfamily (14%) TonB-dependent receptor, plug domain (13.9%) TonB-dependent receptor-like (13.4%)" AWDRLDLLYEETENLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (34.1%) GO:0005737 (31.8%) GO:0008734 (34.1%) 'de novo' NAD+ biosynthetic process from L-aspartate (34.1%) cytoplasm (31.8%) L-aspartate oxidase activity (34.1%) "IPR005288 (17.3%) IPR003953 (16.8%) IPR015939 (16.8%)" "L-aspartate oxidase (17.3%) FAD-dependent oxidoreductase 2, FAD-binding domain (16.8%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.8%)" AVTDVENVTLGDGTTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (38.9%) IPR033985 (33.3%) IPR011990 (27.8%)" "RagB/SusD domain (38.9%) SusD-like, N-terminal (33.3%) Tetratricopeptide-like helical domain superfamily (27.8%)" APECYPMTLGLGFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella ALTFTVGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) AKDGEFFVTDWLR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0003677 (100%) DNA binding (100%) "IPR018004 (57.1%) IPR017880 (42.9%)" "KilA/APSES-type HTH, DNA-binding (57.1%) KilA, N-terminal (42.9%)" LQSLPQQVMLLMNNLPVGYFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (33.3%) GO:0005829 (33.3%) GO:0004056 (33.3%) L-arginine biosynthetic process via ornithine (33.3%) cytosol (33.3%) argininosuccinate lyase activity (33.3%) "IPR009049 (17.1%) IPR020557 (17.1%) IPR022761 (17.1%)" "Argininosuccinate lyase (17.1%) Fumarate lyase, conserved site (17.1%) Fumarate lyase, N-terminal (17.1%)" SFLPLLMGFGCNVPAVMATR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005886 (25.1%) "GO:0005525 (25.1%) GO:0015093 (25.1%) GO:0046914 (24.4%)" plasma membrane (25.1%) "GTP binding (25.1%) ferrous iron transmembrane transporter activity (25.1%) transition metal ion binding (24.4%)" "IPR003373 (9.2%) IPR011642 (9.2%) IPR041069 (9.2%)" "Ferrous iron transport protein B (9.2%) Nucleoside transporter/FeoB GTPase, Gate domain (9.2%) FeoB, cytosolic helical domain (9.2%)" LDMSEFSESFNASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (16.7%) GO:0034605 (16.7%)" GO:0005737 (16.7%) "GO:0005524 (16.7%) GO:0008233 (16.7%) GO:0016887 (16.7%)" "proteolysis (16.7%) cellular response to heat (16.7%)" cytoplasm (16.7%) "ATP binding (16.7%) peptidase activity (16.7%) ATP hydrolysis activity (16.7%)" "IPR001270 (9.1%) IPR001943 (9.1%) IPR003593 (9.1%)" "ClpA/B family (9.1%) UVR domain (9.1%) AAA+ ATPase domain (9.1%)" LAGLVNALTGLFYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0008643 (32.9%) GO:0006814 (1.3%)" GO:0005886 (32.9%) GO:0015293 (32.9%) "carbohydrate transport (32.9%) sodium ion transport (1.3%)" plasma membrane (32.9%) symporter activity (32.9%) "IPR039672 (51%) IPR036259 (46.9%) IPR001927 (2%)" "Lactose permease-like (51%) MFS transporter superfamily (46.9%) Sodium:galactoside symporter (2%)" GNVDVNLTDDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.2%) IPR023996 (34.2%) IPR037066 (31.6%)" "TonB-dependent receptor, plug domain (34.2%) TonB-dependent outer membrane protein, SusC/RagA (34.2%) TonB-dependent receptor, plug domain superfamily (31.6%)" NAMLANMASSLLLSEHKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR000456 (33.3%) IPR036373 (33.3%) IPR047859 (33.3%)" "Large ribosomal subunit protein bL17 (33.3%) Large ribosomal subunit protein bL17 superfamily (33.3%) Large ribosomal subunit protein bL17, conserved site (33.3%)" LYDLHKAEDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" AAYESMVTVYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QYGGAQEVASQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) NGFTDNLLQEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) VDDAAYDCVGGYFQYLQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" SHVCHYDYVVSAEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016788 (82.8%) GO:0016787 (17.2%)" "hydrolase activity, acting on ester bonds (82.8%) hydrolase activity (17.2%)" "IPR037459 (34.9%) IPR013830 (33.7%) IPR036514 (31.3%)" "Rhamnogalacturonan acetylesterase RhgT-like (34.9%) SGNH hydrolase-type esterase domain (33.7%) SGNH hydrolase superfamily (31.3%)" LMEMNNLK root 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (12.8%) GO:0044550 (12.8%) GO:0016567 (3.8%)" "GO:0005737 (19.2%) GO:0005680 (3.8%) GO:0016020 (3.8%)" "GO:0004315 (12.8%) GO:0033818 (11.5%) GO:0046872 (1.3%)" "fatty acid biosynthetic process (12.8%) secondary metabolite biosynthetic process (12.8%) protein ubiquitination (3.8%)" "cytoplasm (19.2%) anaphase-promoting complex (3.8%) membrane (3.8%)" "3-oxoacyl-[acyl-carrier-protein] synthase activity (12.8%) beta-ketoacyl-acyl-carrier-protein synthase III activity (11.5%) metal ion binding (1.3%)" "IPR013747 (14.7%) IPR013751 (14.7%) IPR016039 (14.7%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (14.7%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (14.7%) Thiolase-like (14.7%)" VFGGFSTNFSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" KPLADAGFHMLCAHCDSPTFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.5%) GO:0005737 (19.3%) "GO:0004177 (20.5%) GO:0008270 (20.5%) GO:0008237 (19.3%)" proteolysis (20.5%) cytoplasm (19.3%) "aminopeptidase activity (20.5%) zinc ion binding (20.5%) metallopeptidase activity (19.3%)" "IPR001948 (51.5%) IPR023358 (48.5%)" "Peptidase M18 (51.5%) Peptidase M18, domain 2 (48.5%)" LQDLELPMLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23%) "GO:0000155 (24.3%) GO:0003700 (23%) GO:0043565 (23%)" membrane (23%) "phosphorelay sensor kinase activity (24.3%) DNA-binding transcription factor activity (23%) sequence-specific DNA binding (23%)" "IPR003594 (6.7%) IPR003661 (6.7%) IPR005467 (6.7%)" "Histidine kinase/HSP90-like ATPase domain (6.7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.7%) Histidine kinase domain (6.7%)" HSLEHVDEYDFNEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.8%) GO:0005737 (32.4%) GO:0008734 (33.8%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.8%) cytoplasm (32.4%) L-aspartate oxidase activity (33.8%) "IPR003953 (17%) IPR005288 (17%) IPR015939 (17%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17%) L-aspartate oxidase (17%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (17%)" ALQFPTVFNLLGPLVNPSQPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.18 (100%) anthranilate phosphoribosyltransferase (100%) GO:0000162 (25.2%) GO:0005829 (25.2%) "GO:0004048 (25.2%) GO:0000287 (24.4%)" L-tryptophan biosynthetic process (25.2%) cytosol (25.2%) "anthranilate phosphoribosyltransferase activity (25.2%) magnesium ion binding (24.4%)" "IPR000312 (20.5%) IPR005940 (20.5%) IPR017459 (20.5%)" "Glycosyl transferase, family 3 (20.5%) Anthranilate phosphoribosyl transferase (20.5%) Glycosyl transferase family 3, N-terminal domain (20.5%)" ALDHELDKTLAELQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.1.1.72 (100%) site-specific DNA-methyltransferase (adenine-specific) (100%) "GO:0009307 (21.2%) GO:0032259 (21.2%)" "GO:0003677 (21.2%) GO:0008170 (21.2%) GO:0009007 (13.3%)" "DNA restriction-modification system (21.2%) methylation (21.2%)" "DNA binding (21.2%) N-methyltransferase activity (21.2%) site-specific DNA-methyltransferase (adenine-specific) activity (13.3%)" "IPR002052 (17.1%) IPR003356 (17.1%) IPR051537 (17.1%)" "DNA methylase, N-6 adenine-specific, conserved site (17.1%) DNA methylase, adenine-specific (17.1%) DNA Adenine N(4)/N(6)-Methyltransferase (17.1%)" SVAVEEFK root 3.1.21.3 (100%) type I site-specific deoxyribonuclease (100%) "GO:0005975 (23.9%) GO:0045493 (7.6%) GO:0009307 (0.5%)" "GO:0016020 (1.1%) GO:0005829 (0.5%)" "GO:0004553 (31.5%) GO:0030246 (27.7%) GO:0016787 (3.3%)" "carbohydrate metabolic process (23.9%) xylan catabolic process (7.6%) DNA restriction-modification system (0.5%)" "membrane (1.1%) cytosol (0.5%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (31.5%) carbohydrate binding (27.7%) hydrolase activity (3.3%)" "IPR006710 (12.7%) IPR023296 (12.2%) IPR005084 (11.6%)" "Glycoside hydrolase, family 43 (12.7%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (12.2%) Carbohydrate binding module family 6 (11.6%)" LRDALFSR root "6.1.1.4 (98.5%) 4.1.1.31 (1.2%) 1.13.11.20 (0.1%)" "leucine--tRNA ligase (98.5%) phosphoenolpyruvate carboxylase (1.2%) cysteine dioxygenase (0.1%)" "GO:0006429 (19%) GO:0006099 (0.2%) GO:0006107 (0.2%)" "GO:0005829 (19.2%) GO:0005739 (0.7%) GO:0005886 (0.4%)" "GO:0005524 (19.4%) GO:0004823 (19%) GO:0002161 (18.9%)" "leucyl-tRNA aminoacylation (19%) tricarboxylic acid cycle (0.2%) oxaloacetate metabolic process (0.2%)" "cytosol (19.2%) mitochondrion (0.7%) plasma membrane (0.4%)" "ATP binding (19.4%) leucine-tRNA ligase activity (19%) aminoacyl-tRNA deacylase activity (18.9%)" "IPR002302 (12.2%) IPR025709 (12.1%) IPR014729 (12%)" "Leucine-tRNA ligase (12.2%) Leucyl-tRNA synthetase, editing domain (12.1%) Rossmann-like alpha/beta/alpha sandwich fold (12%)" DPLTVSAWWPFNNADLTQMPAVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (44.3%) IPR042278 (41%) IPR011493 (14.8%)" "Fimbrillin-like 1 (44.3%) Fimbrillin-like 1, N-terminal (41%) GLUG (14.8%)" HYEGLLYQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (17.4%) IPR014729 (17.4%) IPR014730 (17.4%)" "Electron transfer flavoprotein alpha subunit/FixB (17.4%) Rossmann-like alpha/beta/alpha sandwich fold (17.4%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (17.4%)" SDLLDAVDSVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000723 (25%) GO:0006281 (25%)" GO:0016020 (24.3%) "GO:0003678 (25%) GO:0003677 (0.7%)" "telomere maintenance (25%) DNA repair (25%)" membrane (24.3%) "DNA helicase activity (25%) DNA binding (0.7%)" "IPR003593 (20.4%) IPR010285 (20.4%) IPR051055 (20.4%)" "AAA+ ATPase domain (20.4%) DNA helicase Pif1-like, DEAD-box helicase domain (20.4%) PIF1 DNA helicase (20.4%)" VNPQVPLFLTYYTLYPLAGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (20.4%) GO:0009252 (20.4%) GO:0071555 (20.4%)" "GO:0016740 (20.4%) GO:0004180 (18.2%)" "regulation of cell shape (20.4%) peptidoglycan biosynthetic process (20.4%) cell wall organization (20.4%)" "transferase activity (20.4%) carboxypeptidase activity (18.2%)" "IPR005490 (25.7%) IPR052905 (25.7%) IPR045380 (24.8%)" "L,D-transpeptidase catalytic domain (25.7%) L,D-transpeptidase YkuD-like (25.7%) L,D-transpeptidase, scaffold domain (24.8%)" QLLDLGLK root "1.1.1.40 (23.1%) 1.1.1.38 (16.9%) 2.3.2.27 (12.3%)" "malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (23.1%) malate dehydrogenase (oxaloacetate-decarboxylating) (16.9%) RING-type E3 ubiquitin transferase (12.3%)" "GO:0046677 (3.3%) GO:0016567 (1.4%) GO:0071596 (1.2%)" "GO:0005737 (4%) GO:0005829 (4%) GO:0005886 (3.6%)" "GO:0046872 (11.9%) GO:0051287 (6.3%) GO:0004470 (4.2%)" "response to antibiotic (3.3%) protein ubiquitination (1.4%) ubiquitin-dependent protein catabolic process via the N-end rule pathway (1.2%)" "cytoplasm (4%) cytosol (4%) plasma membrane (3.6%)" "metal ion binding (11.9%) NAD binding (6.3%) malic enzyme activity (4.2%)" "IPR036291 (4.2%) IPR012301 (4%) IPR012302 (4%)" "NAD(P)-binding domain superfamily (4.2%) Malic enzyme, N-terminal domain (4%) Malic enzyme, NAD-binding (4%)" KDGYNHLYLCTLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" DAAMQVLAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (52.6%) IPR011990 (47.4%)" "Tetratricopeptide repeat (52.6%) Tetratricopeptide-like helical domain superfamily (47.4%)" TLDEVVVVAYGTTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" SLLVDDVSYFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.- (100%) Transferases for other substituted phosphate groups (100%) GO:0032049 (33%) GO:0005886 (33%) "GO:0008808 (33%) GO:0016787 (1.1%)" cardiolipin biosynthetic process (33%) plasma membrane (33%) "cardiolipin synthase activity (33%) hydrolase activity (1.1%)" "IPR001736 (20%) IPR022924 (20%) IPR025202 (20%)" "Phospholipase D/Transphosphatidylase (20%) Cardiolipin synthase (20%) Phospholipase D-like domain (20%)" LCGLPGLVLAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR005901 (100%) GLPGLI family protein (100%) NWDFNMFCNAAFGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" SAYLEAYSAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018485 (21.1%) IPR050406 (21.1%) IPR018484 (19.7%)" "Carbohydrate kinase FGGY, C-terminal (21.1%) FGGY Carbohydrate Kinase (21.1%) Carbohydrate kinase FGGY, N-terminal (19.7%)" EVGDEDYEYQVQFSAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025874 (89.7%) IPR011990 (10.3%)" "Double zinc ribbon (89.7%) Tetratricopeptide-like helical domain superfamily (10.3%)" QWLATTR root "1.1.1.36 (84%) 5.6.2.4 (12%) 2.3.2.3 (4%)" "acetoacetyl-CoA reductase (84%) DNA 3'-5' helicase (12%) lysyltransferase (4%)" "GO:0006629 (8.1%) GO:0032787 (7.6%) GO:0042619 (7.6%)" "GO:0005737 (8.5%) GO:0009279 (6.6%) GO:0016020 (3.8%)" "GO:0018454 (7.6%) GO:0015344 (6.6%) GO:0016787 (4.3%)" "lipid metabolic process (8.1%) monocarboxylic acid metabolic process (7.6%) poly-hydroxybutyrate biosynthetic process (7.6%)" "cytoplasm (8.5%) cell outer membrane (6.6%) membrane (3.8%)" "acetoacetyl-CoA reductase activity (7.6%) siderophore uptake transmembrane transporter activity (6.6%) hydrolase activity (4.3%)" "IPR036291 (6.7%) IPR002347 (4.9%) IPR011283 (4.9%)" "NAD(P)-binding domain superfamily (6.7%) Short-chain dehydrogenase/reductase SDR (4.9%) Acetoacetyl-CoA reductase (4.9%)" GELPLEVQDLEDDLAGLTTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" NQNPLLTLESCDKQLLGLVCAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" QYQEFVPHGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (13.8%) IPR011659 (13.8%) IPR012393 (13.8%)" "Tail specific protease (13.8%) WD40-like beta-propeller (13.8%) Tricorn protease (13.8%)" SEAENLATAEYPLLHYGSNGDHNQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VKNLFELHALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" VLPLNDKGELNLDEFANLFTER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.8.1.7 (100%) cysteine desulfurase (100%) GO:0006534 (33.3%) "GO:0030170 (33.3%) GO:0031071 (33.3%)" cysteine metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) cysteine desulfurase activity (33.3%)" "IPR000192 (14.3%) IPR010970 (14.3%) IPR015421 (14.3%)" "Aminotransferase class V domain (14.3%) Cysteine desulfurase, SufS (14.3%) Pyridoxal phosphate-dependent transferase, major domain (14.3%)" VVYNVVK root "5.2.1.8 (36.4%) 2.7.13.3 (18.2%) 1.5.1.54 (9.1%)" "peptidylprolyl isomerase (36.4%) histidine kinase (18.2%) methylenetetrahydrofolate reductase (NADH) (9.1%)" "GO:0071555 (6.7%) GO:1901678 (6.7%) GO:0005975 (5.2%)" "GO:0016020 (9%) GO:0030288 (6.7%) GO:0005576 (5.2%)" "GO:0004650 (5.2%) GO:0004930 (4.5%) GO:0005524 (3%)" "cell wall organization (6.7%) iron coordination entity transport (6.7%) carbohydrate metabolic process (5.2%)" "membrane (9%) outer membrane-bounded periplasmic space (6.7%) extracellular region (5.2%)" "polygalacturonase activity (5.2%) G protein-coupled receptor activity (4.5%) ATP binding (3%)" "IPR011852 (17.7%) IPR002491 (4.5%) IPR051313 (4.5%)" "TRAP transporter solute receptor, TAXI family (17.7%) ABC transporter periplasmic binding domain (4.5%) Bacterial iron-siderophore binding (4.5%)" NMEGATVDMTVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) ADLGLTYDEDVLR Bacteria Bacteria "IPR048441 (48.5%) IPR048496 (48.5%) IPR014999 (2.9%)" "DUF1846, C-terminal (48.5%) DUF1846, N-terminal domain (48.5%) Family of unknown function DUF1846 (2.9%)" GLLFGALNEESLAWK Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (33.9%) IPR014358 (33.9%) IPR036291 (32.1%)" "Short-chain dehydrogenase/reductase SDR (33.9%) Enoyl-[acyl-carrier-protein] reductase (NADH) (33.9%) NAD(P)-binding domain superfamily (32.1%)" SNKLQSLPQQVMLLMNNLPVGYFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (33.3%) GO:0005829 (33.3%) GO:0004056 (33.3%) L-arginine biosynthetic process via ornithine (33.3%) cytosol (33.3%) argininosuccinate lyase activity (33.3%) "IPR009049 (17.1%) IPR020557 (17.1%) IPR022761 (17.1%)" "Argininosuccinate lyase (17.1%) Fumarate lyase, conserved site (17.1%) Fumarate lyase, N-terminal (17.1%)" TQTYFSANYMDQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (26.7%) GO:0009279 (73.3%) iron ion transport (26.7%) cell outer membrane (73.3%) "IPR012910 (13.5%) IPR023996 (13.5%) IPR023997 (13.5%)" "TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.5%)" LLQEAQSHLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006779 (20%) GO:0005737 (20%) "GO:0004109 (20%) GO:0046872 (20%) GO:0051539 (20%)" porphyrin-containing compound biosynthetic process (20%) cytoplasm (20%) "coproporphyrinogen oxidase activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR004559 (16.8%) IPR006638 (16.8%) IPR007197 (16.8%)" "Heme chaperone HemW-like (16.8%) Elp3/MiaA/NifB-like, radical SAM core domain (16.8%) Radical SAM (16.8%)" QLDLMSMFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.3%) IPR015883 (17.3%) IPR025705 (17.3%)" "PA14 domain (17.3%) Glycoside hydrolase family 20, catalytic domain (17.3%) Beta-hexosaminidase (17.3%)" FVTGLQYR Bacteria Bacteria 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) GO:0006096 (31.8%) "GO:0016020 (2.3%) GO:0009279 (1.1%)" "GO:0004619 (31.8%) GO:0046872 (31.8%) GO:0016301 (1.1%)" glycolytic process (31.8%) "membrane (2.3%) cell outer membrane (1.1%)" "phosphoglycerate mutase activity (31.8%) metal ion binding (31.8%) kinase activity (1.1%)" "IPR004456 (24.6%) IPR006124 (24.6%) IPR017850 (24.6%)" "2,3-bisphosphoglycerate-independent phosphoglycerate mutase (24.6%) Metalloenzyme (24.6%) Alkaline-phosphatase-like, core domain superfamily (24.6%)" NYRPVGVDADVFTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009306 (50%) GO:0005886 (50%) protein secretion (50%) plasma membrane (50%) IPR007452 (100%) Translocation and assembly module TamB, C-terminal domain (100%) YPDVLPNTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (48.6%) GO:0016787 (51.4%) membrane (48.6%) hydrolase activity (51.4%) "IPR005079 (33.9%) IPR052193 (33.9%) IPR029055 (32.1%)" "Peptidase C45, hydrolase domain (33.9%) Peptidase C59 family enzymes (33.9%) Nucleophile aminohydrolases, N-terminal (32.1%)" LAMLMAMLTQAFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005886 (80.4%) "GO:0015297 (9.8%) GO:0042910 (9.8%)" plasma membrane (80.4%) "antiporter activity (9.8%) xenobiotic transmembrane transporter activity (9.8%)" "IPR050833 (54.5%) IPR002797 (38.9%) IPR002528 (6.6%)" "Polysaccharide Biosynthesis and Transport (54.5%) Polysaccharide biosynthesis protein (38.9%) Multi antimicrobial extrusion protein (6.6%)" TELSYATPSWYPSYWGGSEFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LNGSFDLYHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.6%) IPR039426 (15.6%) IPR036942 (14.7%)" "TonB-dependent outer membrane protein, SusC/RagA (15.6%) TonB-dependent receptor-like (15.6%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.7%)" LADLYLMYAEACAAFGGASGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32.1%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32.1%)" NLEAEPTENER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.1 (100%) NAD(+) synthase (glutamine-hydrolyzing) (100%) GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.7%) IPR003694 (14.7%) IPR014445 (14.7%)" "Carbon-nitrogen hydrolase (14.7%) NAD(+) synthetase (14.7%) Glutamine-dependent NAD(+) synthetase (14.7%)" EMFGADTK Bacteria Bacteria "6.1.1.20 (99.3%) 3.3.2.10 (0.7%)" "phenylalanine--tRNA ligase (99.3%) soluble epoxide hydrolase (0.7%)" "GO:0006432 (16.2%) GO:0046464 (0.6%) GO:0043039 (0.1%)" "GO:0005737 (16.2%) GO:0016020 (0.6%)" "GO:0000049 (16.4%) GO:0004826 (16.4%) GO:0005524 (16.4%)" "phenylalanyl-tRNA aminoacylation (16.2%) acylglycerol catabolic process (0.6%) tRNA aminoacylation (0.1%)" "cytoplasm (16.2%) membrane (0.6%)" "tRNA binding (16.4%) phenylalanine-tRNA ligase activity (16.4%) ATP binding (16.4%)" "IPR002319 (14.2%) IPR045864 (14.2%) IPR004188 (14.1%)" "Phenylalanyl-tRNA synthetase (14.2%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.2%) Phenylalanine-tRNA ligase, class II, N-terminal (14.1%)" KGLDADVQEQATLDTEEGSLLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QDSQYGVCLFKDELVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" VVLAATAR root "5.6.2.2 (78.3%) 3.1.2.22 (10.9%) 2.3.1.31 (3.8%)" "DNA topoisomerase (ATP-hydrolyzing) (78.3%) palmitoyl-protein hydrolase (10.9%) homoserine O-acetyltransferase (3.8%)" "GO:0006265 (11%) GO:0006261 (8%) GO:0006631 (1.2%)" "GO:0005737 (10.3%) GO:0005694 (8%) GO:0005886 (1.6%)" "GO:0005524 (11.5%) GO:0003677 (11%) GO:0046872 (8.6%)" "DNA topological change (11%) DNA-templated DNA replication (8%) fatty acid metabolic process (1.2%)" "cytoplasm (10.3%) chromosome (8%) plasma membrane (1.6%)" "ATP binding (11.5%) DNA binding (11%) metal ion binding (8.6%)" "IPR001241 (6.7%) IPR006171 (6.7%) IPR013506 (6.7%)" "DNA topoisomerase, type IIA (6.7%) TOPRIM domain (6.7%) DNA topoisomerase, type IIA, subunit B, domain 2 (6.7%)" LMELESEWVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (58.8%) IPR012547 (41.2%)" "AAA-ATPase-like domain (58.8%) PD-(D/E)XK nuclease superfamily 9 (41.2%)" LMGLADDRLQLATVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EFAMGDVEEEVFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR049208 (35.1%) IPR032533 (33.3%) IPR011004 (31.6%)" "Domain of unknown function DUF6819 (35.1%) Domain of unknown function DUF4954 (33.3%) Trimeric LpxA-like superfamily (31.6%)" LLALKPEALLVSPFENSGGYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071281 (100%) cellular response to iron ion (100%) "IPR002491 (50%) IPR050902 (50%)" "ABC transporter periplasmic binding domain (50%) ABC Transporter Solute-Binding (50%)" LSTLSGYNLTDNTQLLGAVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (48.6%) GO:0016787 (51.4%) membrane (48.6%) hydrolase activity (51.4%) "IPR005079 (33.9%) IPR052193 (33.9%) IPR029055 (32.1%)" "Peptidase C45, hydrolase domain (33.9%) Peptidase C59 family enzymes (33.9%) Nucleophile aminohydrolases, N-terminal (32.1%)" SGGYVNGMLDNLCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (25%) GO:0031564 (25%)" GO:0005829 (25%) GO:0003723 (25%) "DNA-templated transcription termination (25%) transcription antitermination (25%)" cytosol (25%) RNA binding (25%) "IPR006027 (33.3%) IPR011605 (33.3%) IPR035926 (33.3%)" "NusB/RsmB/TIM44 (33.3%) NusB antitermination factor (33.3%) NusB-like superfamily (33.3%)" TADYVLMFGGLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" ASGLSAAVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009313 (49.1%) "GO:0004556 (49.1%) GO:0016301 (1.8%)" oligosaccharide catabolic process (49.1%) "alpha-amylase activity (49.1%) kinase activity (1.8%)" "IPR006047 (26.2%) IPR013780 (25.2%) IPR017853 (24.3%)" "Glycosyl hydrolase family 13, catalytic domain (26.2%) Glycosyl hydrolase, all-beta (25.2%) Glycoside hydrolase superfamily (24.3%)" RPHFNNLQFVSADGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" LATTPFLPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.9%) "GO:0005886 (16.3%) GO:0016020 (0.6%)" "GO:0016655 (16.9%) GO:0051537 (16.9%) GO:0009055 (16.3%)" sodium ion transport (16.9%) "plasma membrane (16.3%) membrane (0.6%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.9%) 2 iron, 2 sulfur cluster binding (16.9%) electron transfer activity (16.3%)" "IPR001433 (10.2%) IPR008333 (10.2%) IPR010205 (10.2%)" "Oxidoreductase FAD/NAD(P)-binding (10.2%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.2%) Na(+)-translocating NADH-quinone reductase subunit F (10.2%)" EFLPLLQPAAESGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (26.3%) GO:0005737 (6.9%) "GO:0140662 (26.3%) GO:0005524 (24.8%) GO:0016853 (9%)" protein refolding (26.3%) cytoplasm (6.9%) "ATP-dependent protein folding chaperone (26.3%) ATP binding (24.8%) isomerase activity (9%)" "IPR001844 (19.4%) IPR027409 (19.2%) IPR027410 (19%)" "Chaperonin Cpn60/GroEL (19.4%) GroEL-like apical domain superfamily (19.2%) TCP-1-like chaperonin intermediate domain superfamily (19%)" DYQSLEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005841 (14.3%) IPR005844 (14.3%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase superfamily (14.3%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.3%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" LQGGPMDYTPGLFETK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (50.6%) GO:0016787 (49.4%)" "carbohydrate binding (50.6%) hydrolase activity (49.4%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" YNDMLLKPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) MNEVLSADNAMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.9%) GO:0016020 (0.3%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.9%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.9%) membrane (0.3%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.9%)" "IPR001264 (16.9%) IPR001460 (16.9%) IPR050396 (16.9%)" "Glycosyl transferase, family 51 (16.9%) Penicillin-binding protein, transpeptidase (16.9%) Glycosyltransferase 51/Transpeptidase (16.9%)" QAGQLPPYSTLVFDLELVSLVKPEVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (31.6%) IPR001179 (31.6%) IPR046357 (30.5%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (31.6%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (31.6%) Peptidyl-prolyl cis-trans isomerase domain superfamily (30.5%)" LSNTQDDKEANEAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0016989 (50%) membrane (50%) sigma factor antagonist activity (50%) "IPR006860 (34.8%) IPR012373 (34.8%) IPR032508 (30.4%)" "FecR protein (34.8%) Fe(2+)-dicitrate sensor, transmembrane component (34.8%) Protein FecR, C-terminal (30.4%)" VQTWVEEYLSTPAYNHLLFCNQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR008886 (34.1%) IPR023214 (33%) IPR029058 (33%)" "Uncharacterised protein family UPF0227/Esterase YqiA (34.1%) HAD superfamily (33%) Alpha/Beta hydrolase fold (33%)" LTAMAGVR root "7.2.1.1 (99%) 1.6.5.- (1%)" "NADH:ubiquinone reductase (Na(+)-transporting) (99%) With a quinone or similar compound as acceptor (1%)" "GO:0006814 (14.1%) GO:0022904 (14.1%) GO:0044718 (3.5%)" "GO:0005886 (15%) GO:0009276 (14.1%) GO:0012505 (14.1%)" "GO:0016655 (14.1%) GO:0015344 (3.5%) GO:0004129 (0.6%)" "sodium ion transport (14.1%) respiratory electron transport chain (14.1%) siderophore transmembrane transport (3.5%)" "plasma membrane (15%) Gram-negative-bacterium-type cell wall (14.1%) endomembrane system (14.1%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (14.1%) siderophore uptake transmembrane transporter activity (3.5%) cytochrome-c oxidase activity (0.6%)" "IPR003667 (22.9%) IPR050133 (22.9%) IPR010967 (22.7%)" "NqrDE/RnfAE (22.9%) Ion-translocating oxidoreductase complex subunit A/E (22.9%) Na(+)-translocating NADH-quinone reductase subunit E (22.7%)" LALTDKEGYFTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.5%) IPR023996 (15.5%) IPR023997 (15.5%)" "TonB-dependent receptor, plug domain (15.5%) TonB-dependent outer membrane protein, SusC/RagA (15.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.5%)" ASDAKPLLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DAEVTVDMK Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LLMFGSNAYQGLTNDQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030170 (51.1%) GO:0008483 (44.7%) GO:0016740 (4.3%)" "pyridoxal phosphate binding (51.1%) transaminase activity (44.7%) transferase activity (4.3%)" "IPR004839 (17.1%) IPR050087 (17.1%) IPR001917 (16.4%)" "Aminotransferase, class I/classII, large domain (17.1%) 8-amino-7-oxononanoate synthase class-II (17.1%) Aminotransferase, class-II, pyridoxal-phosphate binding site (16.4%)" VVGLQTDKPLK root "2.3.1.54 (99.8%) 2.3.1.- (0.2%)" "formate C-acetyltransferase (99.8%) Transferring groups other than amino-acyl groups (0.2%)" "GO:0006006 (31.6%) GO:0005975 (0.8%)" "GO:0005829 (33.4%) GO:0016020 (0.2%)" "GO:0008861 (33.4%) GO:0016829 (0.6%) GO:0008168 (0.1%)" "glucose metabolic process (31.6%) carbohydrate metabolic process (0.8%)" "cytosol (33.4%) membrane (0.2%)" "formate C-acetyltransferase activity (33.4%) lyase activity (0.6%) methyltransferase activity (0.1%)" "IPR004184 (20.4%) IPR050244 (20.4%) IPR001150 (19.8%)" "Pyruvate formate lyase domain (20.4%) Autonomous Glycyl Radical Cofactor (20.4%) Glycine radical domain (19.8%)" KETQTFLGTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030435 (91.5%) GO:0030288 (4.3%) GO:0016740 (4.3%) sporulation resulting in formation of a cellular spore (91.5%) outer membrane-bounded periplasmic space (4.3%) transferase activity (4.3%) "IPR013486 (13%) IPR013693 (13%) IPR001173 (12.4%)" "Sporulation stage II protein D, amidase enhancer LytB (13%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (13%) Glycosyltransferase 2-like (12.4%)" WHCLPGQPLTELDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.18 (100%) methionyl aminopeptidase (100%) GO:0006508 (25%) "GO:0004239 (25%) GO:0070006 (25%) GO:0046914 (23.4%)" proteolysis (25%) "initiator methionyl aminopeptidase activity (25%) metalloaminopeptidase activity (25%) transition metal ion binding (23.4%)" "IPR000994 (25.8%) IPR002467 (25.8%) IPR001714 (24.2%)" "Peptidase M24 (25.8%) Peptidase M24A, methionine aminopeptidase, subfamily 1 (25.8%) Peptidase M24, methionine aminopeptidase (24.2%)" QARPGAEMHVVLVDNGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (32.4%) GO:0051536 (1%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (32.4%) iron-sulfur cluster binding (1%)" "IPR003741 (14.3%) IPR004452 (14.3%) IPR017896 (14.3%)" "LUD domain (14.3%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.3%)" LLHQLHQPADHPLNLYHPEGEYLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.1.1.- (66.7%) 2.1.1.191 (33.3%)" "Methyltransferases (66.7%) 23S rRNA (cytosine(1962)-C(5))-methyltransferase (33.3%)" "GO:0032259 (20.4%) GO:0006364 (19.3%)" GO:0005737 (20%) "GO:0008168 (20.4%) GO:0003723 (20%)" "methylation (20.4%) rRNA processing (19.3%)" cytoplasm (20%) "methyltransferase activity (20.4%) RNA binding (20%)" "IPR019614 (17%) IPR002478 (16.8%) IPR041532 (16.8%)" "S-adenosylmethionine-dependent methyltransferase (17%) PUA domain (16.8%) RlmI-like, PUA domain (16.8%)" LTGTGFDVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) KVTLLNGPHTVLSPVTYLSGVNLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.4%) GO:0005829 (32.4%) "GO:0008926 (32.4%) GO:0009026 (2.8%)" mannitol catabolic process (32.4%) cytosol (32.4%) "mannitol-1-phosphate 5-dehydrogenase activity (32.4%) tagaturonate reductase activity (2.8%)" "IPR013118 (21.7%) IPR013131 (21.7%) IPR008927 (18.9%)" "Mannitol dehydrogenase, C-terminal (21.7%) Mannitol dehydrogenase, N-terminal (21.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.9%)" QTWSFLVGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (50%) GO:0015134 (50%) membrane (50%) hexuronate transmembrane transporter activity (50%) "IPR011701 (25.3%) IPR020846 (25.3%) IPR050382 (25.3%)" "Major facilitator superfamily (25.3%) Major facilitator superfamily domain (25.3%) Major Facilitator Superfamily Sodium/Anion Cotransporter (25.3%)" EKDEVQHFVSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.3%) IPR006512 (25.3%) IPR050144 (25.3%)" "Regulator of K+ conductance, C-terminal (25.3%) YidE/YbjL duplication (25.3%) AAE Transporter (25.3%)" KLSLVTSGGFGTMGFGLPAALGATFGAPDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.9%) IPR012000 (12.9%) IPR045229 (12.9%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.9%) Thiamine pyrophosphate enzyme, central domain (12.9%) Thiamine pyrophosphate enzyme (12.9%)" LVPDLETWHADGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006101 (8.3%) IPR006102 (8.3%) IPR006103 (8.3%)" "Glycoside hydrolase, family 2 (8.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8.3%) Glycoside hydrolase family 2, catalytic domain (8.3%)" SEYLEMPLFDLTER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.4%) GO:0005829 (16.4%) "GO:0003677 (16.4%) GO:0005524 (16.4%) GO:0043138 (16.4%)" recombinational repair (16.4%) cytosol (16.4%) "DNA binding (16.4%) ATP binding (16.4%) 3'-5' DNA helicase activity (16.4%)" "IPR000212 (20.3%) IPR014016 (20.3%) IPR014017 (20.3%)" "DNA helicase, UvrD/REP type (20.3%) UvrD-like helicase, ATP-binding domain (20.3%) UvrD-like DNA helicase, C-terminal (20.3%)" HVNPNDNEACAEALRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NVPGVSGLFVEEVSGLPQLQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (34.2%) IPR004763 (34.2%) IPR027463 (31.6%)" "Acriflavin resistance protein (34.2%) Cation efflux system CusA-like (34.2%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.6%)" LDFTELNSLLNLAAER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016787 (100%) hydrolase activity (100%) "IPR012878 (50%) IPR049046 (50%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (50%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (50%)" AKLDVGFNATLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (2.6%) GO:0009279 (94.7%) GO:0015344 (2.6%) siderophore transmembrane transport (2.6%) cell outer membrane (94.7%) siderophore uptake transmembrane transporter activity (2.6%) "IPR012910 (15.2%) IPR023997 (15.2%) IPR039426 (15.2%)" "TonB-dependent receptor, plug domain (15.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.2%) TonB-dependent receptor-like (15.2%)" DLEGVLR root "6.1.1.21 (25.6%) 2.7.9.4 (24%) 6.1.1.7 (6.2%)" "histidine--tRNA ligase (25.6%) alpha-glucan, water dikinase (24%) alanine--tRNA ligase (6.2%)" "GO:0006427 (3.3%) GO:0006419 (0.9%) GO:0046656 (0.6%)" "GO:0005737 (8.3%) GO:0009507 (3.4%) GO:0005886 (1.5%)" "GO:0005524 (12.8%) GO:0046872 (5.9%) GO:0016301 (4.4%)" "histidyl-tRNA aminoacylation (3.3%) alanyl-tRNA aminoacylation (0.9%) folic acid biosynthetic process (0.6%)" "cytoplasm (8.3%) chloroplast (3.4%) plasma membrane (1.5%)" "ATP binding (12.8%) metal ion binding (5.9%) kinase activity (4.4%)" "IPR002192 (2.9%) IPR045864 (2.9%) IPR013815 (2.7%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (2.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (2.9%) ATP-grasp fold, subdomain 1 (2.7%)" EFSDYCR root "1.14.13.59 (66.7%) 1.13.11.2 (11.1%) 2.1.1.- (11.1%)" "L-lysine N(6)-monooxygenase (NADPH) (66.7%) catechol 2,3-dioxygenase (11.1%) Methyltransferases (11.1%)" "GO:0006396 (8.9%) GO:0016556 (8.9%) GO:0032259 (8.9%)" "GO:0044167 (8.9%) GO:0016020 (3.6%) GO:0005829 (1.8%)" "GO:0047091 (10.7%) GO:0003723 (8.9%) GO:0004386 (8.9%)" "RNA processing (8.9%) mRNA modification (8.9%) methylation (8.9%)" "host cell endoplasmic reticulum membrane (8.9%) membrane (3.6%) cytosol (1.8%)" "L-lysine 6-monooxygenase (NADPH) activity (10.7%) RNA binding (8.9%) helicase activity (8.9%)" "IPR026444 (38.6%) IPR025700 (8.6%) IPR036188 (8.6%)" "Secretion system, C-terminal sorting domain (38.6%) L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase (8.6%) FAD/NAD(P)-binding domain superfamily (8.6%)" FAENHDEALHLQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016779 (91.7%) GO:0016740 (8.3%)" "nucleotidyltransferase activity (91.7%) transferase activity (8.3%)" "IPR036554 (37.3%) IPR004821 (21.6%) IPR050385 (21.6%)" "GHMP kinase, C-terminal domain superfamily (37.3%) Cytidyltransferase-like domain (21.6%) Archaeal FAD synthase (21.6%)" LALYFTHDWDVTNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (91.9%) GO:0015344 (8.1%) cell outer membrane (91.9%) siderophore uptake transmembrane transporter activity (8.1%) "IPR036942 (91.9%) IPR039426 (8.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (91.9%) TonB-dependent receptor-like (8.1%)" ANVWADECER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005975 (47.7%) GO:0045493 (3.1%)" "GO:0016787 (46.2%) GO:0046559 (3.1%)" "carbohydrate metabolic process (47.7%) xylan catabolic process (3.1%)" "hydrolase activity (46.2%) alpha-glucuronidase activity (3.1%)" "IPR031924 (24.8%) IPR041437 (24.8%) IPR042301 (24.8%)" "Glycosyl hydrolase family 115 (24.8%) Gylcosyl hydrolase 115 C-terminal domain (24.8%) Glycosyl hydrolase 115 superfamily (24.8%)" HTTEDVLACTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006289 (12.3%) GO:0006281 (0.3%)" "GO:0005737 (12.6%) GO:0009380 (12.3%)" "GO:0003677 (12.6%) GO:0004518 (12.6%) GO:0005524 (12.6%)" "nucleotide-excision repair (12.3%) DNA repair (0.3%)" "cytoplasm (12.6%) excinuclease repair complex (12.3%)" "DNA binding (12.6%) nuclease activity (12.6%) ATP binding (12.6%)" "IPR041102 (17%) IPR041552 (17%) IPR004602 (16.5%)" "UvrA, interaction domain (17%) UvrA DNA-binding domain (17%) UvrABC system subunit A (16.5%)" VGFQYVNDTTWGGHAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016747 (100%) acyltransferase activity, transferring groups other than amino-acyl groups (100%) "IPR000182 (34.5%) IPR050680 (34.5%) IPR016181 (31%)" "GNAT domain (34.5%) YpeA/RimI acetyltransferase (34.5%) Acyl-CoA N-acyltransferase (31%)" VYFLPVTPFFVTELLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.7%) 6.3.4.16 (49.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.7%) carbamoyl-phosphate synthase (ammonia) (49.3%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" ELQDNLFNLPNDSMLYHLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016301 (50.8%) GO:0005524 (49.2%)" "kinase activity (50.8%) ATP binding (49.2%)" "IPR002192 (34.1%) IPR051549 (34.1%) IPR013815 (31.9%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (34.1%) Phosphoenolpyruvate Utilizing Enzyme (34.1%) ATP-grasp fold, subdomain 1 (31.9%)" VYLNGNNLWLWTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" GATLQYHDVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) GO:0016020 (48.7%) "GO:0004467 (49.4%) GO:0016405 (1.3%) GO:0016874 (0.6%)" membrane (48.7%) "long-chain fatty acid-CoA ligase activity (49.4%) CoA-ligase activity (1.3%) ligase activity (0.6%)" "IPR000873 (25.7%) IPR020845 (25.4%) IPR042099 (24.8%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.4%) ANL, N-terminal domain (24.8%)" EGLLPCNLYGEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" GFHNQEVPLPQQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR019734 (26%) IPR025738 (26%) IPR011990 (24.7%)" "Tetratricopeptide repeat (26%) Aerotolerance-related protein BatD (26%) Tetratricopeptide-like helical domain superfamily (24.7%)" KFYYVEEGCWLSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001383 (25%) IPR026569 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL28, bacteria (25%) Large ribosomal subunit protein bL28 (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" TPATVANCFSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (25%) IPR012334 (25%) IPR033427 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) Domain of unknown function DUF5123 (25%)" LQYNDTDANSSSDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTVQSTGLGCDNLDLVVNELDALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.5%) IPR035994 (47.5%)" "Nucleoside phosphorylase domain (52.5%) Nucleoside phosphorylase superfamily (47.5%)" FQLLAGER root "2.7.1.130 (42.9%) 2.7.7.65 (42.9%) 1.1.1.267 (14.3%)" "tetraacyldisaccharide 4'-kinase (42.9%) diguanylate cyclase (42.9%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (14.3%)" "GO:0007059 (25.9%) GO:0045881 (16.3%) GO:0006355 (0.3%)" "GO:0005694 (25.9%) GO:0009295 (0.7%) GO:0005886 (0.6%)" "GO:0003677 (25.8%) GO:0005507 (0.8%) GO:0016491 (0.8%)" "chromosome segregation (25.9%) positive regulation of sporulation resulting in formation of a cellular spore (16.3%) regulation of DNA-templated transcription (0.3%)" "chromosome (25.9%) nucleoid (0.7%) plasma membrane (0.6%)" "DNA binding (25.8%) copper ion binding (0.8%) oxidoreductase activity (0.8%)" "IPR003115 (16.1%) IPR050336 (16.1%) IPR004437 (16%)" "ParB-like, N-terminal domain (16.1%) Chromosome-partitioning and nucleoid occlusion protein (16.1%) ParB/RepB/Spo0J partition protein (16%)" EMLTPWSTNAVELTQNMSLDGLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.7%) IPR010918 (11.7%) IPR040707 (11.7%)" "Phosphoribosylformylglycinamidine synthase PurL (11.7%) PurM-like, C-terminal domain (11.7%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.7%)" VTFTYETDWGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.7%) IPR008969 (48.3%)" "Family of unknown function DUF5686 (51.7%) Carboxypeptidase-like, regulatory domain superfamily (48.3%)" FLLFLQGCPMR Bacteria Bacteria 1.97.1.4 (100%) [formate-C-acetyltransferase]-activating enzyme (100%) GO:0005737 (21.1%) "GO:0043365 (21.1%) GO:0046872 (21.1%) GO:0051539 (21.1%)" cytoplasm (21.1%) "[formate-C-acetyltransferase]-activating enzyme activity (21.1%) metal ion binding (21.1%) 4 iron, 4 sulfur cluster binding (21.1%)" "IPR001989 (18.8%) IPR007197 (18.8%) IPR012838 (18.8%)" "Radical-activating enzyme, conserved site (18.8%) Radical SAM (18.8%) Pyruvate formate-lyase 1 activating enzyme (18.8%)" YYEQNNQAHSAQLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) "IPR003423 (50%) IPR050737 (50%)" "Outer membrane efflux protein (50%) Unknown (50%)" TVAVAGSELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" LKQQLVLTGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" EVSAAQLLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (33.3%) IPR011042 (33.3%) IPR029058 (33.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (33.3%) Six-bladed beta-propeller, TolB-like (33.3%) Alpha/Beta hydrolase fold (33.3%)" VDELLSYLSQYFTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0018773 (47.8%) GO:0046872 (47.8%) GO:0016853 (4.3%)" "acetylpyruvate hydrolase activity (47.8%) metal ion binding (47.8%) isomerase activity (4.3%)" "IPR011234 (50%) IPR036663 (50%)" "Fumarylacetoacetase-like, C-terminal (50%) Fumarylacetoacetase-like, C-terminal domain superfamily (50%)" ALGTTGAPHPDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.1.148 (100%) thymidylate synthase (FAD) (100%) "GO:0006231 (18.6%) GO:0032259 (6.8%)" "GO:0004799 (18.6%) GO:0050660 (18.6%) GO:0050797 (18.6%)" "dTMP biosynthetic process (18.6%) methylation (6.8%)" "thymidylate synthase activity (18.6%) flavin adenine dinucleotide binding (18.6%) thymidylate synthase (FAD) activity (18.6%)" "IPR003669 (52.4%) IPR036098 (47.6%)" "Thymidylate synthase ThyX (52.4%) Thymidylate synthase ThyX superfamily (47.6%)" QLLLDALMK root "GO:0009166 (1.8%) GO:0043171 (1.8%) GO:0051603 (1.8%)" "GO:0005886 (37.5%) GO:0005737 (1.8%) GO:0005739 (1.8%)" "GO:0008381 (39.3%) GO:0000166 (1.8%) GO:0004222 (1.8%)" "nucleotide catabolic process (1.8%) peptide catabolic process (1.8%) proteolysis involved in protein catabolic process (1.8%)" "plasma membrane (37.5%) cytoplasm (1.8%) mitochondrion (1.8%)" "mechanosensitive monoatomic ion channel activity (39.3%) nucleotide binding (1.8%) metalloendopeptidase activity (1.8%)" "IPR006685 (15.2%) IPR045275 (15.2%) IPR049278 (15.2%)" "Mechanosensitive ion channel MscS (15.2%) Mechanosensitive ion channel MscS, archaea/bacteria type (15.2%) Mechanosensitive ion channel MscS, C-terminal domain (15.2%)" LLTPSVTDLAASGDFYMANAPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" EDLLGLLVPVLFNPEVMPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50%) GO:0046872 (50%)" "hydrolase activity (50%) metal ion binding (50%)" IPR039461 (100%) Peptidase family M49 (100%) RAENGMLYDPVTLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20.1%) GO:0006183 (20.1%)" "GO:0003938 (20.1%) GO:0046872 (20.1%) GO:0000166 (19.6%)" "GMP biosynthetic process (20.1%) GTP biosynthetic process (20.1%)" "IMP dehydrogenase activity (20.1%) metal ion binding (20.1%) nucleotide binding (19.6%)" "IPR000644 (16.8%) IPR001093 (16.8%) IPR005990 (16.8%)" "CBS domain (16.8%) IMP dehydrogenase/GMP reductase (16.8%) Inosine-5'-monophosphate dehydrogenase (16.8%)" NYKTELSYATPSWYPSYWGGSEFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VALAWMSNWQYANQVPTQQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.6%) IPR013148 (14.6%) IPR013189 (14.6%)" "Glycoside hydrolase, family 32 (14.6%) Glycosyl hydrolase family 32, N-terminal (14.6%) Glycosyl hydrolase family 32, C-terminal (14.6%)" AMTALFELLNGNR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "GO:0005524 (50.2%) GO:0016887 (49.8%)" "ATP binding (50.2%) ATP hydrolysis activity (49.8%)" "IPR032781 (20.1%) IPR051309 (20.1%) IPR003439 (19.9%)" "ABC-transporter extension domain (20.1%) ABC transporter ABCF subfamily ATPase (20.1%) ABC transporter-like, ATP-binding domain (19.9%)" LQPGCYTMPELPVLDMLPGTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25.2%) IPR010190 (25.2%) IPR032094 (25.2%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.2%) Diaminopimelate dehydrogenase, Ddh (25.2%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25.2%)" MNELELR root "2.2.1.7 (23.5%) 1.3.1.9 (11.1%) 2.7.7.65 (11.1%)" "1-deoxy-D-xylulose-5-phosphate synthase (23.5%) enoyl-[acyl-carrier-protein] reductase (NADH) (11.1%) diguanylate cyclase (11.1%)" "GO:0006508 (3.6%) GO:0000278 (1.8%) GO:0010389 (1.8%)" "GO:0005737 (4.2%) GO:0005829 (2.6%) GO:0005634 (2.3%)" "GO:0046872 (4%) GO:0005524 (3.1%) GO:0070006 (3.1%)" "proteolysis (3.6%) mitotic cell cycle (1.8%) regulation of G2/M transition of mitotic cell cycle (1.8%)" "cytoplasm (4.2%) cytosol (2.6%) nucleus (2.3%)" "metal ion binding (4%) ATP binding (3.1%) metalloaminopeptidase activity (3.1%)" "IPR000587 (2.7%) IPR050422 (2.7%) IPR000994 (2.6%)" "Creatinase, N-terminal (2.7%) Xaa-Pro aminopeptidase P (2.7%) Peptidase M24 (2.6%)" TGYNYGTGTDEYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" FDFTGNNDVAAFCR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005975 (50%) "GO:0004553 (25%) GO:0004565 (25%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (25%) beta-galactosidase activity (25%)" "IPR001944 (14%) IPR008979 (14%) IPR017853 (14%)" "Glycoside hydrolase, family 35 (14%) Galactose-binding-like domain superfamily (14%) Glycoside hydrolase superfamily (14%)" NLGSLENYGLELAFNVKPLVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" SMYKPLVGNTTLSQYYYDNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" ELYDPVLTFQLSNDFHVR Pseudomonadati Bacteria Pseudomonadati "3.5.1.100 (75%) 2.3.1.- (8.3%) 3.5.-.- (8.3%)" "(R)-amidase (75%) Transferring groups other than amino-acyl groups (8.3%) Acting on carbon-nitrogen bonds, other than peptide bonds (8.3%)" "GO:0016747 (62.5%) GO:0016787 (37%) GO:0004040 (0.5%)" "acyltransferase activity, transferring groups other than amino-acyl groups (62.5%) hydrolase activity (37%) amidase activity (0.5%)" "IPR003010 (20.2%) IPR001110 (20%) IPR036526 (20%)" "Carbon-nitrogen hydrolase (20.2%) Uncharacterised protein family UPF0012, conserved site (20%) Carbon-nitrogen hydrolase superfamily (20%)" LPEWVNK root "3.6.4.13 (58.3%) 3.2.1.22 (12.5%) 3.1.4.38 (8.3%)" "RNA helicase (58.3%) alpha-galactosidase (12.5%) glycerophosphocholine cholinephosphodiesterase (8.3%)" "GO:0005975 (6.6%) GO:0006508 (1.3%) GO:0016579 (1.3%)" "GO:0016020 (4.4%) GO:0005634 (3.5%) GO:0005829 (0.9%)" "GO:0004035 (18.1%) GO:0004553 (6.6%) GO:0016616 (6.6%)" "carbohydrate metabolic process (6.6%) proteolysis (1.3%) protein deubiquitination (1.3%)" "membrane (4.4%) nucleus (3.5%) cytosol (0.9%)" "alkaline phosphatase activity (18.1%) hydrolase activity, hydrolyzing O-glycosyl compounds (6.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (6.6%)" "IPR002591 (10.8%) IPR026263 (10.5%) IPR017850 (10%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (10.8%) Alkaline phosphatase, prokaryotic (10.5%) Alkaline-phosphatase-like, core domain superfamily (10%)" NSHEVYLTEAGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR000847 (20.4%) IPR005119 (20.4%) IPR050950 (20.4%)" "LysR, HTH, N-terminal domain (20.4%) LysR, substrate-binding (20.4%) HTH-type LysR transcriptional regulators (20.4%)" AVTFPER root "2.3.1.31 (44.2%) 2.4.2.1 (18.6%) 3.1.1.4 (11.6%)" "homoserine O-acetyltransferase (44.2%) purine-nucleoside phosphorylase (18.6%) phospholipase A2 (11.6%)" "GO:0009086 (6.9%) GO:0009092 (6.9%) GO:0009116 (3.1%)" "GO:0005737 (11.7%) GO:0005576 (2.1%) GO:0005634 (1.7%)" "GO:0004414 (6.9%) GO:0003677 (3.8%) GO:0004731 (3.1%)" "methionine biosynthetic process (6.9%) homoserine metabolic process (6.9%) nucleoside metabolic process (3.1%)" "cytoplasm (11.7%) extracellular region (2.1%) nucleus (1.7%)" "homoserine O-acetyltransferase activity (6.9%) DNA binding (3.8%) purine-nucleoside phosphorylase activity (3.1%)" "IPR029058 (8.3%) IPR000073 (7.7%) IPR008220 (6.4%)" "Alpha/Beta hydrolase fold (8.3%) Alpha/beta hydrolase fold-1 (7.7%) Homoserine/serine acetyltransferase MetX-like (6.4%)" NSSTNTFYMVNTLAPLYPLYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YYCCAGTALGAAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009100 (100%) glycoprotein metabolic process (100%) "IPR007074 (48.6%) IPR052942 (48.6%) IPR043519 (2.7%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (48.6%) Lipopolysaccharide cholinephosphotransferase (48.6%) Nucleotidyltransferase superfamily (2.7%)" GQGVHTWESEPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.15 (100%) biotin--[biotin carboxyl-carrier protein] ligase (100%) GO:0005737 (50%) GO:0004077 (50%) cytoplasm (50%) biotin--[biotin carboxyl-carrier protein] ligase activity (50%) "IPR004143 (26.7%) IPR004408 (26.7%) IPR045864 (24.8%)" "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain (26.7%) Biotin--acetyl-CoA-carboxylase ligase (26.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (24.8%)" LFENLLGK root "3.5.1.2 (52.4%) 2.3.2.8 (23.8%) 2.3.2.26 (14.3%)" "glutaminase (52.4%) arginyltransferase (23.8%) HECT-type E3 ubiquitin transferase (14.3%)" "GO:0006537 (11.5%) GO:0006543 (11.5%) GO:0000160 (2.1%)" "GO:0016020 (10.4%) GO:0005737 (7.3%) GO:0005886 (2.1%)" "GO:0004359 (11.5%) GO:0004057 (5.2%) GO:0005524 (3.1%)" "glutamate biosynthetic process (11.5%) L-glutamine catabolic process (11.5%) phosphorelay signal transduction system (2.1%)" "membrane (10.4%) cytoplasm (7.3%) plasma membrane (2.1%)" "glutaminase activity (11.5%) arginyl-tRNA--protein transferase activity (5.2%) ATP binding (3.1%)" "IPR012338 (7.4%) IPR015868 (7.4%) IPR007471 (3.4%)" "Beta-lactamase/transpeptidase-like (7.4%) Glutaminase (7.4%) N-end aminoacyl transferase, N-terminal (3.4%)" NFVPGSCGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.8%) IPR020845 (25.8%) IPR042099 (24.2%)" "AMP-dependent synthetase/ligase domain (25.8%) AMP-binding, conserved site (25.8%) ANL, N-terminal domain (24.2%)" VLHLQDSSFLEEGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0004601 (100%) peroxidase activity (100%) "IPR013766 (21.1%) IPR036249 (20.5%) IPR004879 (19.9%)" "Thioredoxin domain (21.1%) Thioredoxin-like superfamily (20.5%) Spermatogenesis-associated protein 20-like, TRX domain (19.9%)" LNKAPFFMYGEVCTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (67.6%) "GO:0016787 (23.5%) GO:0016829 (8.8%)" carbohydrate metabolic process (67.6%) "hydrolase activity (23.5%) lyase activity (8.8%)" "IPR006047 (24.2%) IPR013783 (24.2%) IPR017853 (24.2%)" "Glycosyl hydrolase family 13, catalytic domain (24.2%) Immunoglobulin-like fold (24.2%) Glycoside hydrolase superfamily (24.2%)" HAWDWTHEHGGLLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.2%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.2%)" "IPR001412 (9.4%) IPR002300 (9.4%) IPR002303 (9.4%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.4%) Aminoacyl-tRNA synthetase, class Ia (9.4%) Valine-tRNA ligase (9.4%)" TTLQALAETLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.49 (100%) hydroxymethylpyrimidine kinase (100%) GO:0009228 (20%) GO:0005829 (20%) "GO:0005524 (20%) GO:0008902 (20%) GO:0008972 (20%)" thiamine biosynthetic process (20%) cytosol (20%) "ATP binding (20%) hydroxymethylpyrimidine kinase activity (20%) phosphomethylpyrimidine kinase activity (20%)" "IPR004399 (33.3%) IPR013749 (33.3%) IPR029056 (33.3%)" "Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase domain (33.3%) Pyridoxamine kinase/Phosphomethylpyrimidine kinase (33.3%) Ribokinase-like (33.3%)" YNLATTNLPASFVNSVQVLSNHQAVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0004180 (100%) carboxypeptidase activity (100%) IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) ADLPENLK root "3.4.21.53 (60%) 3.1.3.- (10%) 2.1.1.37 (5%)" "endopeptidase La (60%) Phosphoric monoester hydrolases (10%) DNA (cytosine-5-)-methyltransferase (5%)" "GO:0042274 (16.7%) GO:0006412 (16.6%) GO:0006515 (0.7%)" "GO:0015935 (16.6%) GO:0005737 (0.9%) GO:0016020 (0.4%)" "GO:0019843 (16.7%) GO:0003735 (16.7%) GO:0005524 (1.4%)" "ribosomal small subunit biogenesis (16.7%) translation (16.6%) protein quality control for misfolded or incompletely synthesized proteins (0.7%)" "small ribosomal subunit (16.6%) cytoplasm (0.9%) membrane (0.4%)" "rRNA binding (16.7%) structural constituent of ribosome (16.7%) ATP binding (1.4%)" "IPR036986 (13.6%) IPR002942 (13.5%) IPR001912 (13.5%)" "RNA-binding S4 domain superfamily (13.6%) RNA-binding S4 domain (13.5%) Small ribosomal subunit protein uS4, N-terminal (13.5%)" QLLTELPAK root "3.4.13.18 (88.9%) 1.1.1.100 (5.6%) 4.98.1.1 (5.6%)" "cytosol non-specific dipeptidase (88.9%) 3-oxoacyl-[acyl-carrier-protein] reductase (5.6%) protoporphyrin ferrochelatase (5.6%)" "GO:0006508 (21.9%) GO:0006783 (1.4%) GO:0006950 (1.4%)" "GO:0005829 (21.9%) GO:0005737 (1.4%)" "GO:0046872 (23.3%) GO:0070573 (21.9%) GO:0003677 (1.4%)" "proteolysis (21.9%) heme biosynthetic process (1.4%) response to stress (1.4%)" "cytosol (21.9%) cytoplasm (1.4%)" "metal ion binding (23.3%) metallodipeptidase activity (21.9%) DNA binding (1.4%)" "IPR001160 (27.6%) IPR002933 (27.6%) IPR011650 (27.6%)" "Peptidase M20C, Xaa-His dipeptidase (27.6%) Peptidase M20 (27.6%) Peptidase M20, dimerisation domain (27.6%)" QYYGETAELLK Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.7%) GO:0006096 (12.7%) GO:0019563 (12.7%)" "GO:0005829 (12.7%) GO:0016020 (12%)" GO:0004807 (12.7%) "gluconeogenesis (12.7%) glycolytic process (12.7%) glycerol catabolic process (12.7%)" "cytosol (12.7%) membrane (12%)" triose-phosphate isomerase activity (12.7%) "IPR000652 (17.1%) IPR020861 (17.1%) IPR022896 (16.9%)" "Triosephosphate isomerase (17.1%) Triosephosphate isomerase, active site (17.1%) Triosephosphate isomerase, bacterial/eukaryotic (16.9%)" DVATPYNSWQPYQAYLLDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (52.6%) IPR050811 (47.4%)" "PBP domain (52.6%) Phosphate-binding ABC transporter substrate-binding (47.4%)" MTYASEFALFADTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YTLGFQEALYVGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.4%) IPR021120 (20.4%) IPR011051 (19.7%)" "5-keto 4-deoxyuronate isomerase (20.4%) KduI/IolB isomerase (20.4%) RmlC-like cupin domain superfamily (19.7%)" DDKGNSLAETTDGTFYTLGNLTTLLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" ELVEALDETDNLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006355 (50%) GO:0003677 (50%) regulation of DNA-templated transcription (50%) DNA binding (50%) "IPR000792 (25%) IPR012312 (25%) IPR016032 (25%)" "Transcription regulator LuxR, C-terminal (25%) Hemerythrin-like (25%) Signal transduction response regulator, C-terminal effector (25%)" NHEAYGEEFFLETTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (50%) GO:0008460 (50%) nucleotide-sugar metabolic process (50%) dTDP-glucose 4,6-dehydratase activity (50%) "IPR036291 (34.3%) IPR005888 (31.5%) IPR001509 (26.9%)" "NAD(P)-binding domain superfamily (34.3%) dTDP-glucose 4,6-dehydratase (31.5%) NAD-dependent epimerase/dehydratase (26.9%)" TNLLGWASTSANAGLELGTGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) LSEQTGVPCFVAYYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.99.28 (100%) glucose-fructose oxidoreductase (100%) "GO:0000166 (94.9%) GO:0016491 (2.6%) GO:0047061 (2.6%)" "nucleotide binding (94.9%) oxidoreductase activity (2.6%) glucose-fructose oxidoreductase activity (2.6%)" "IPR000683 (25.2%) IPR055170 (25.2%) IPR036291 (24.5%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.2%) GFO/IDH/MocA-like oxidoreductase domain (25.2%) NAD(P)-binding domain superfamily (24.5%)" NAPTHQYNVAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.2%) IPR023996 (15.2%) IPR023997 (15.2%)" "TonB-dependent receptor, plug domain (15.2%) TonB-dependent outer membrane protein, SusC/RagA (15.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.2%)" MLTVQNLALQFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.2%) IPR003593 (20.2%) IPR032781 (20.2%)" "ABC transporter-like, ATP-binding domain (20.2%) AAA+ ATPase domain (20.2%) ABC-transporter extension domain (20.2%)" YSNGLELNAVQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" FLAELNK root "2.7.11.1 (62.9%) 3.5.1.- (5.9%) 3.5.1.28 (5.7%)" "non-specific serine/threonine protein kinase (62.9%) In linear amides (5.9%) N-acetylmuramoyl-L-alanine amidase (5.7%)" "GO:0015031 (6.4%) GO:0032456 (6.4%) GO:0045214 (3.3%)" "GO:0005768 (6.4%) GO:0005634 (3.5%) GO:0030018 (3.3%)" "GO:0005524 (4.1%) GO:0046872 (3.7%) GO:0004674 (3.4%)" "protein transport (6.4%) endocytic recycling (6.4%) sarcomere organization (3.3%)" "endosome (6.4%) nucleus (3.5%) Z disc (3.3%)" "ATP binding (4.1%) metal ion binding (3.7%) protein serine/threonine kinase activity (3.4%)" "IPR029705 (7.2%) IPR013783 (4.1%) IPR003599 (4%)" "VPS35 endosomal protein sorting factor-like (7.2%) Immunoglobulin-like fold (4.1%) Immunoglobulin domain subtype (4%)" LVELSGLEGSSPALER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (18.8%) "GO:0000155 (20.3%) GO:0003700 (20.3%) GO:0005524 (20.3%)" membrane (18.8%) "phosphorelay sensor kinase activity (20.3%) DNA-binding transcription factor activity (20.3%) ATP binding (20.3%)" "IPR001789 (7.8%) IPR003594 (7.8%) IPR003661 (7.8%)" "Signal transduction response regulator, receiver domain (7.8%) Histidine kinase/HSP90-like ATPase domain (7.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.8%)" SKFYPSLTLSGTGAFTNSGGMGLVNPGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" MELDGYCVLEGDNLEVYDHMNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (46.9%) GO:0003746 (53.1%) cytoplasm (46.9%) translation elongation factor activity (53.1%) "IPR014039 (20.7%) IPR036402 (20.7%) IPR001816 (19.5%)" "Translation elongation factor EFTs/EF1B, dimerisation (20.7%) Elongation factor Ts, dimerisation domain superfamily (20.7%) Translation elongation factor EFTs/EF1B (19.5%)" EVDAQKLK root "7.4.2.8 (57.1%) 5.6.2.3 (28.6%) 3.6.3.4 (14.3%)" "protein-secreting ATPase (57.1%) DNA 5'-3' helicase (28.6%) Transferred entry: 7.2.2.9 (14.3%)" "GO:0010143 (14.8%) GO:0008654 (8.8%) GO:0006605 (1.4%)" "GO:0016020 (14.8%) GO:0005886 (2.5%) GO:0005829 (1.8%)" "GO:0016791 (14.8%) GO:0090447 (14.8%) GO:0005524 (3.2%)" "cutin biosynthetic process (14.8%) phospholipid biosynthetic process (8.8%) protein targeting (1.4%)" "membrane (14.8%) plasma membrane (2.5%) cytosol (1.8%)" "phosphatase activity (14.8%) glycerol-3-phosphate 2-O-acyltransferase activity (14.8%) ATP binding (3.2%)" "IPR002123 (20.7%) IPR056462 (19.7%) IPR027417 (2.9%)" "Phospholipid/glycerol acyltransferase (20.7%) Glycerol-3-phosphate acyltransferase RAM2/GPAT1-8, HAD-like domain (19.7%) P-loop containing nucleoside triphosphate hydrolase (2.9%)" RVHGNMPAMTGTTQAEVQAQLEHER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.2%) IPR012944 (34.2%) IPR033985 (31.6%)" "Tetratricopeptide-like helical domain superfamily (34.2%) RagB/SusD domain (34.2%) SusD-like, N-terminal (31.6%)" WLLLEPLSMPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TSLVLDELLSGLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (25.4%) IPR017871 (25.4%) IPR003593 (24.6%)" "ABC transporter-like, ATP-binding domain (25.4%) ABC transporter-like, conserved site (25.4%) AAA+ ATPase domain (24.6%)" VQAFMKDLELQALELGLPCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (49.6%) GO:0004356 (50.4%) glutamine biosynthetic process (49.6%) glutamine synthetase activity (50.4%) "IPR008146 (14.4%) IPR027303 (14.4%) IPR052725 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, glycine-rich site (14.4%) Glutamine Synthetase Type-3 (14.4%)" TEEEFKELAESAFTFAPQVLVEESLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.4.16 (50.7%) 6.3.5.5 (49.3%)" "carbamoyl-phosphate synthase (ammonia) (50.7%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (49.3%)" "GO:0006541 (14.1%) GO:0006221 (13.3%) GO:0006526 (13.3%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (13.3%) L-arginine biosynthetic process (13.3%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.5%) IPR011761 (10.5%) IPR005483 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%) Carbamoyl phosphate synthase, CPSase domain (10.2%)" TVTDYLDSLGVDPESLMYDNFG Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (17%) "GO:0005886 (15.9%) GO:0016020 (1.1%)" "GO:0016655 (17%) GO:0051537 (17%) GO:0009055 (15.9%)" sodium ion transport (17%) "plasma membrane (15.9%) membrane (1.1%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (17%) 2 iron, 2 sulfur cluster binding (17%) electron transfer activity (15.9%)" "IPR001433 (10.1%) IPR001709 (10.1%) IPR008333 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" KADDLFALR root 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006298 (14.4%) "GO:0032300 (14.4%) GO:0005840 (0.5%) GO:0005739 (0.2%)" "GO:0005524 (14.9%) GO:0016887 (14.4%) GO:0030983 (14.4%)" mismatch repair (14.4%) "mismatch repair complex (14.4%) ribosome (0.5%) mitochondrion (0.2%)" "ATP binding (14.9%) ATP hydrolysis activity (14.4%) mismatched DNA binding (14.4%)" "IPR002099 (8.4%) IPR038973 (8.4%) IPR013507 (8.3%)" "DNA mismatch repair protein MutL/Mlh/PMS (8.4%) DNA mismatch repair protein MutL/Mlh/Pms-like (8.4%) DNA mismatch repair protein, S5 domain 2-like (8.3%)" LCTMSNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (48%) IPR012640 (32%) IPR013783 (20%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (48%) Membrane lipoprotein, lipid attachment site (32%) Immunoglobulin-like fold (20%)" SVANYCDTFQYMLDFVNDKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella KVDQSLSPFNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.180 (100%) FAD:protein FMN transferase (100%) GO:0016020 (33.3%) "GO:0016740 (34.7%) GO:0046872 (31.9%)" membrane (33.3%) "transferase activity (34.7%) metal ion binding (31.9%)" "IPR024932 (52.1%) IPR003374 (47.9%)" "Flavin transferase ApbE (52.1%) ApbE-like superfamily (47.9%)" EHLGGAYAMVTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.7%) IPR012910 (20.7%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.7%) TonB-dependent receptor, plug domain (20.7%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" DDAGWAWGLPTSNLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SLQLDLNPFTLVGATTR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "3.6.4.- (88.9%) 3.6.4.12 (11.1%)" "Acting on ATP; involved in cellular and subcellular movement (88.9%) DNA helicase (11.1%)" "GO:0006281 (12.6%) GO:0006310 (12.6%)" "GO:0005737 (12.4%) GO:0048476 (12.1%) GO:0016020 (0.2%)" "GO:0005524 (12.6%) GO:0009378 (12.6%) GO:0000400 (12.1%)" "DNA repair (12.6%) DNA recombination (12.6%)" "cytoplasm (12.4%) Holliday junction resolvase complex (12.1%) membrane (0.2%)" "ATP binding (12.6%) four-way junction helicase activity (12.6%) four-way junction DNA binding (12.1%)" "IPR004605 (12.6%) IPR008824 (12.6%) IPR027417 (12.6%)" "Holliday junction branch migration complex subunit RuvB (12.6%) RuvB-like, AAA+ ATPase domain (12.6%) P-loop containing nucleoside triphosphate hydrolase (12.6%)" EDVPVLELHDMTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR008979 (25%) IPR013830 (25%) IPR036514 (25%)" "Galactose-binding-like domain superfamily (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" MLEFPMENLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SGQGLYSFFDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.8%) GO:0008360 (13.7%) GO:0009252 (13.7%)" GO:0005737 (13.7%) "GO:0005524 (14.8%) GO:0008716 (14.8%) GO:0046872 (14.8%)" "cell wall organization (14.8%) regulation of cell shape (13.7%) peptidoglycan biosynthetic process (13.7%)" cytoplasm (13.7%) "ATP binding (14.8%) D-alanine-D-alanine ligase activity (14.8%) metal ion binding (14.8%)" "IPR000291 (14.4%) IPR005905 (14.4%) IPR011095 (14.4%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.4%) D-alanine--D-alanine ligase (14.4%) D-alanine--D-alanine ligase, C-terminal (14.4%)" LTLVGVSGSKEEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SLFVSTLQAYFEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (80%) GO:0003676 (20%)" "ATP binding (80%) nucleic acid binding (20%)" "IPR018631 (33.3%) IPR012547 (31.7%) IPR027417 (30.2%)" "AAA-ATPase-like domain (33.3%) PD-(D/E)XK nuclease superfamily 9 (31.7%) P-loop containing nucleoside triphosphate hydrolase (30.2%)" QEPDNFLVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) TTGQEPLYYNHQNTGRPVADDNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" LTFYADYYYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" VYDSMDNMTEQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella NVFGMNPLLAALQTAELAVNELGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (42.4%) GO:0005886 (44.1%) "GO:0016787 (11.9%) GO:0016301 (1.7%)" guanosine tetraphosphate metabolic process (42.4%) plasma membrane (44.1%) "hydrolase activity (11.9%) kinase activity (1.7%)" "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" NLDTYDEDALTLALADYQTSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.15 (100%) biotin--[biotin carboxyl-carrier protein] ligase (100%) GO:0005737 (50%) GO:0004077 (50%) cytoplasm (50%) biotin--[biotin carboxyl-carrier protein] ligase activity (50%) "IPR004143 (26.1%) IPR004408 (26.1%) IPR045864 (26.1%)" "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain (26.1%) Biotin--acetyl-CoA-carboxylase ligase (26.1%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (26.1%)" TLFGYPGGSLMPVFDALYGYTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.4%) GO:0009099 (14.4%)" GO:0005948 (14.4%) "GO:0003984 (14.4%) GO:0030976 (14.4%) GO:0050660 (14.4%)" "isoleucine biosynthetic process (14.4%) L-valine biosynthetic process (14.4%)" acetolactate synthase complex (14.4%) "acetolactate synthase activity (14.4%) thiamine pyrophosphate binding (14.4%) flavin adenine dinucleotide binding (14.4%)" "IPR012001 (13.2%) IPR045229 (13.2%) IPR011766 (12.4%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (13.2%) Thiamine pyrophosphate enzyme (13.2%) Thiamine pyrophosphate enzyme, TPP-binding (12.4%)" TVYYFTDVPTTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.9%) "GO:0004222 (33.9%) GO:0046872 (32.3%)" proteolysis (33.9%) "metalloendopeptidase activity (33.9%) metal ion binding (32.3%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" LQEANTQVELLNELGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (18%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (18%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" ALEGQCDHYEPFLPGHYYYSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" YPDVVLESYLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" MSLSLWGK Bacteria Bacteria "GO:0006826 (46.5%) GO:0006811 (2.3%)" "GO:0009279 (48.8%) GO:0005886 (2.3%)" "iron ion transport (46.5%) monoatomic ion transport (2.3%)" "cell outer membrane (48.8%) plasma membrane (2.3%)" "IPR000531 (25.3%) IPR039426 (25.3%) IPR012910 (24.1%)" "TonB-dependent receptor-like, beta-barrel (25.3%) TonB-dependent receptor-like (25.3%) TonB-dependent receptor, plug domain (24.1%)" LNMVTPALFAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.99.18 (100%) DNA-(apurinic or apyrimidinic site) lyase (100%) GO:0006285 (15.2%) "GO:0003677 (15.2%) GO:0019104 (15.2%) GO:0046872 (15.2%)" base-excision repair, AP site formation (15.2%) "DNA binding (15.2%) DNA N-glycosylase activity (15.2%) metal ion binding (15.2%)" "IPR003265 (14.6%) IPR003651 (14.6%) IPR004035 (14.6%)" "HhH-GPD domain (14.6%) Endonuclease III-like, iron-sulphur cluster loop motif (14.6%) Endonuclease III, iron-sulphur binding site (14.6%)" FVSLLAGLDSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20.2%) GO:0005737 (20.2%) "GO:0004815 (20.2%) GO:0005524 (20.2%) GO:0003676 (19.1%)" aspartyl-tRNA aminoacylation (20.2%) cytoplasm (20.2%) "aspartate-tRNA ligase activity (20.2%) ATP binding (20.2%) nucleic acid binding (19.1%)" "IPR004364 (9.3%) IPR029351 (9.3%) IPR002312 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.3%) GAD domain (9.3%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%)" AATLADEVLAGRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NDFALATWAPLSLCEDGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR013189 (15.4%) IPR013320 (14.6%) IPR001362 (14.2%)" "Glycosyl hydrolase family 32, C-terminal (15.4%) Concanavalin A-like lectin/glucanase domain superfamily (14.6%) Glycoside hydrolase, family 32 (14.2%)" GTTDLTTNASDYFVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" AHQQNVVPVVDQALAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (22.8%) GO:0006508 (5.1%)" GO:0005737 (21.5%) "GO:0005506 (21.5%) GO:0061711 (13.9%) GO:0016747 (8.9%)" "tRNA threonylcarbamoyladenosine modification (22.8%) proteolysis (5.1%)" cytoplasm (21.5%) "iron ion binding (21.5%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (13.9%) acyltransferase activity, transferring groups other than amino-acyl groups (8.9%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" ELDYLVQFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR011579 (50%) IPR027417 (50%)" "ATPase domain (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" HQAGFNNYAGDPVSSTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.1.103 (100%) teichoic acid D-alanine hydrolase (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR001466 (34%) IPR050491 (34%) IPR012338 (32%)" "Beta-lactamase-related (34%) Beta-lactamase AmpC-like (34%) Beta-lactamase/transpeptidase-like (32%)" VYEFTGK root "2.5.1.75 (82.6%) 2.7.1.2 (4.3%) 3.1.1.77 (4.3%)" "tRNA dimethylallyltransferase (82.6%) glucokinase (4.3%) acyloxyacyl hydrolase (4.3%)" "GO:0006400 (13.4%) GO:0032259 (5.5%) GO:0006508 (3.9%)" "GO:0016020 (6.3%) GO:0005576 (3.1%) GO:0009279 (1.6%)" "GO:0005524 (13.4%) GO:0052381 (13.4%) GO:0016301 (9.4%)" "tRNA modification (13.4%) methylation (5.5%) proteolysis (3.9%)" "membrane (6.3%) extracellular region (3.1%) cell outer membrane (1.6%)" "ATP binding (13.4%) tRNA dimethylallyltransferase activity (13.4%) kinase activity (9.4%)" "IPR000600 (12.9%) IPR049874 (12.9%) IPR043129 (12.3%)" "ROK family (12.9%) ROK, conserved site (12.9%) ATPase, nucleotide binding domain (12.3%)" DGYLPSLSLTGTLMYSAFTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LAAYNQGLYGDKNQDFAPNYEGDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "Carboxypeptidase-like, regulatory domain superfamily (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" WGTFPSVALGWTLTEEPWLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.9%) IPR012910 (11.9%) IPR023996 (11.9%)" "TonB-dependent receptor-like, beta-barrel (11.9%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" FWHAQHSPSEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000731 (14.4%) GO:0006261 (14.4%)" "GO:0005524 (14.4%) GO:0008047 (14.4%) GO:0016887 (14.4%)" "DNA synthesis involved in DNA repair (14.4%) DNA-templated DNA replication (14.4%)" "ATP binding (14.4%) enzyme activator activity (14.4%) ATP hydrolysis activity (14.4%)" "IPR003593 (14.5%) IPR003959 (14.5%) IPR021886 (14.5%)" "AAA+ ATPase domain (14.5%) ATPase, AAA-type, core (14.5%) MgsA AAA+ ATPase, C-terminal (14.5%)" TDTEYNALNSYAMLHVLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR041700 (100%) Outer membrane protein beta-barrel domain 3 (100%) TTLMVGFPGETDEDFHELLDFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.8.4.4 (100%) [ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase (100%) GO:0006400 (15.5%) "GO:0005829 (15.5%) GO:0005840 (15.5%)" "GO:0035599 (15.5%) GO:0046872 (15.5%) GO:0051539 (15.5%)" tRNA modification (15.5%) "cytosol (15.5%) ribosome (15.5%)" "aspartic acid methylthiotransferase activity (15.5%) metal ion binding (15.5%) 4 iron, 4 sulfur cluster binding (15.5%)" "IPR002792 (10.2%) IPR005839 (10.2%) IPR005840 (10.2%)" "TRAM domain (10.2%) Methylthiotransferase (10.2%) Ribosomal protein uS12 methylthiotransferase RimO (10.2%)" LHAFESVFDGFESFLYVPNTTAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) "GO:0055085 (18.3%) GO:0006814 (15.8%) GO:0022904 (15.8%)" "GO:0005886 (16.7%) GO:0016020 (1.7%)" "GO:0010181 (15.8%) GO:0016655 (15.8%)" "transmembrane transport (18.3%) sodium ion transport (15.8%) respiratory electron transport chain (15.8%)" "plasma membrane (16.7%) membrane (1.7%)" "FMN binding (15.8%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (15.8%)" "IPR004338 (53.7%) IPR010966 (46.3%)" "Ion-translocating oxidoreductase NqrB/RnfD (53.7%) Na(+)-translocating NADH-quinone reductase subunit B (46.3%)" TLLAVTAGTPTAGGFTADKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.7 (100%) 1-deoxy-D-xylulose-5-phosphate synthase (100%) "GO:0016114 (16.4%) GO:0019288 (16.4%) GO:0009228 (15%)" GO:0005829 (16.4%) "GO:0008661 (16.4%) GO:0046872 (15%)" "terpenoid biosynthetic process (16.4%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (16.4%) thiamine biosynthetic process (15%)" cytosol (16.4%) "1-deoxy-D-xylulose-5-phosphate synthase activity (16.4%) metal ion binding (15%)" "IPR005475 (17.1%) IPR005477 (17.1%) IPR033248 (17.1%)" "Transketolase-like, pyrimidine-binding domain (17.1%) Deoxyxylulose-5-phosphate synthase (17.1%) Transketolase, C-terminal domain (17.1%)" SNVYVDLQTLAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004478 (16.7%) GO:0005524 (16.7%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) methionine adenosyltransferase activity (16.7%) ATP binding (16.7%)" "IPR002133 (16.8%) IPR022628 (16.8%) IPR022629 (16.8%)" "S-adenosylmethionine synthetase (16.8%) S-adenosylmethionine synthetase, N-terminal (16.8%) S-adenosylmethionine synthetase, central domain (16.8%)" SLKDPFTFAQTNVMGTLSLLQAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (50%) GO:0008460 (50%) nucleotide-sugar metabolic process (50%) dTDP-glucose 4,6-dehydratase activity (50%) "IPR036291 (33.9%) IPR005888 (32.3%) IPR001509 (22.2%)" "NAD(P)-binding domain superfamily (33.9%) dTDP-glucose 4,6-dehydratase (32.3%) NAD-dependent epimerase/dehydratase (22.2%)" ATLLTSEGEKEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20%) IPR001972 (20%) IPR018080 (20%)" "Band 7 domain (20%) Stomatin/HflK family (20%) Band 7/stomatin-like, conserved site (20%)" ELLDELTK root "2.7.13.3 (25.1%) 2.3.2.26 (18.8%) 2.1.1.228 (12.2%)" "histidine kinase (25.1%) HECT-type E3 ubiquitin transferase (18.8%) tRNA (guanine(37)-N(1))-methyltransferase (12.2%)" "GO:0006352 (8.3%) GO:0006357 (2%) GO:0006281 (1.8%)" "GO:0005634 (10.7%) GO:0030880 (7.2%) GO:0005886 (2.7%)" "GO:0000166 (8.4%) GO:0005524 (2.6%) GO:0061630 (1.9%)" "DNA-templated transcription initiation (8.3%) regulation of transcription by RNA polymerase II (2%) DNA repair (1.8%)" "nucleus (10.7%) RNA polymerase complex (7.2%) plasma membrane (2.7%)" "nucleotide binding (8.4%) ATP binding (2.6%) ubiquitin protein ligase activity (1.9%)" "IPR005574 (6%) IPR006590 (6%) IPR010997 (6%)" "RNA polymerase subunit Rpb4/RPC9 (6%) RNA polymerase Rpb4/RPC9, core (6%) HRDC-like superfamily (6%)" LYFVDDVKFELSPLACAYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.3 (100%) phosphoribosylaminoimidazolecarboxamide formyltransferase (100%) GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (26.7%) IPR016193 (24.4%) IPR024050 (24.4%)" "Bifunctional purine biosynthesis protein PurH-like (26.7%) Cytidine deaminase-like (24.4%) AICAR transformylase, insert domain superfamily (24.4%)" GVEYFCSHLYPQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.3.-.- (100%) Acting on the CH-CH group of donors (100%) "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" LDANNLTEASLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" LLQVGNVLVSPDLLTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR021458 (100%) Rv0495c-like (100%) GLGTADVLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (52.9%) IPR011990 (47.1%)" "RagB/SusD domain (52.9%) Tetratricopeptide-like helical domain superfamily (47.1%)" QQNADGVPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" KSYGGSHLVMGCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.-.-.- (100%) Ligases (100%) "GO:0015977 (21.1%) GO:0006633 (4.1%)" GO:0009317 (21.1%) "GO:0004658 (22.2%) GO:0003989 (21.1%) GO:0016740 (8.9%)" "carbon fixation (21.1%) fatty acid biosynthetic process (4.1%)" acetyl-CoA carboxylase complex (21.1%) "propionyl-CoA carboxylase activity (22.2%) acetyl-CoA carboxylase activity (21.1%) transferase activity (8.9%)" "IPR011762 (19.4%) IPR011763 (19.4%) IPR034733 (19.4%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.4%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.4%)" AVLHVFCDLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.7%) GO:0005829 (20.7%) "GO:0004832 (20.7%) GO:0005524 (20.7%) GO:0002161 (17.2%)" valyl-tRNA aminoacylation (20.7%) cytosol (20.7%) "valine-tRNA ligase activity (20.7%) ATP binding (20.7%) aminoacyl-tRNA deacylase activity (17.2%)" "IPR001412 (9.9%) IPR002300 (9.9%) IPR002303 (9.9%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.9%) Aminoacyl-tRNA synthetase, class Ia (9.9%) Valine-tRNA ligase (9.9%)" LSLHEGGLAPLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (14.6%) IPR004602 (14.6%) IPR017871 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) UvrABC system subunit A (14.6%) ABC transporter-like, conserved site (14.6%)" NNSELVAVYGNFVNR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002547 (8.4%) IPR004495 (8.4%) IPR009080 (8.4%)" "tRNA-binding domain (8.4%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.4%) Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (8.4%)" SSAQNQQSSWLAQFSLSGSAPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR022045 (17.9%) IPR028994 (17.9%) IPR006530 (12.8%)" "Insecticide toxin TcdB middle/N-terminal (17.9%) Integrin alpha, N-terminal (17.9%) YD repeat (12.8%)" GNFTYEAPMLATAWLPLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043741 (100%) Family of unknown function DUF5686 (100%) RTFALLSHPDAGK root "GO:0006449 (15.4%) GO:0006415 (0%) GO:0006352 (0%)" "GO:0005829 (15.9%) GO:0016020 (0%) GO:0000428 (0%)" "GO:0003924 (15.9%) GO:0016150 (15.9%) GO:0005525 (15.9%)" "regulation of translational termination (15.4%) translational termination (0%) DNA-templated transcription initiation (0%)" "cytosol (15.9%) membrane (0%) DNA-directed RNA polymerase complex (0%)" "GTPase activity (15.9%) translation release factor activity, codon nonspecific (15.9%) GTP binding (15.9%)" "IPR004548 (9.2%) IPR000795 (9.2%) IPR027417 (9.2%)" "Peptide chain release factor 3 (9.2%) Translational (tr)-type GTP-binding domain (9.2%) P-loop containing nucleoside triphosphate hydrolase (9.2%)" GLQYEDTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR003741 (34.9%) IPR024185 (32.6%) IPR037171 (32.6%)" "LUD domain (34.9%) 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily (32.6%) NagB/RpiA transferase-like (32.6%)" MEHGLTTATYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SNGYWLGALSTYER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (34.7%) "GO:0004222 (34.7%) GO:0046872 (30.6%)" proteolysis (34.7%) "metalloendopeptidase activity (34.7%) metal ion binding (30.6%)" "IPR001431 (20.5%) IPR007863 (20.5%) IPR011765 (20.5%)" "Peptidase M16, zinc-binding site (20.5%) Peptidase M16, C-terminal (20.5%) Peptidase M16, N-terminal (20.5%)" ASLGAQYDVTPQVGFYLEPGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR011250 (91.7%) IPR025665 (8.3%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (91.7%) Outer membrane protein, beta-barrel domain 2 (8.3%)" TDVEELSDEEWEVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0004521 (50%) GO:0016787 (50%)" "RNA endonuclease activity (50%) hydrolase activity (50%)" "IPR005229 (33.3%) IPR013527 (33.3%) IPR013551 (33.3%)" "Endoribonuclease YicC/YloC-like (33.3%) Endoribonuclease YicC-like, N-terminal (33.3%) Endoribonuclease YicC-like, C-terminal (33.3%)" NNDFAFK root "2.1.1.72 (77.3%) 2.7.7.13 (9.1%) 3.1.21.3 (4.5%)" "site-specific DNA-methyltransferase (adenine-specific) (77.3%) mannose-1-phosphate guanylyltransferase (9.1%) type I site-specific deoxyribonuclease (4.5%)" "GO:0009307 (6.7%) GO:0032259 (6.7%) GO:0015920 (6%)" "GO:0005615 (8.2%) GO:0009279 (6.4%) GO:1990351 (6%)" "GO:0004867 (8.2%) GO:0003677 (6.7%) GO:0008170 (6.7%)" "DNA restriction-modification system (6.7%) methylation (6.7%) lipopolysaccharide transport (6%)" "extracellular space (8.2%) cell outer membrane (6.4%) transporter complex (6%)" "serine-type endopeptidase inhibitor activity (8.2%) DNA binding (6.7%) N-methyltransferase activity (6.7%)" "IPR000215 (6.9%) IPR023796 (6.9%) IPR036186 (6.6%)" "Serpin family (6.9%) Serpin domain (6.9%) Serpin superfamily (6.6%)" QELLENLK root "2.7.7.7 (28.9%) 1.18.1.2 (10.5%) 7.4.2.8 (9.2%)" "DNA-directed DNA polymerase (28.9%) ferredoxin--NADP(+) reductase (10.5%) protein-secreting ATPase (9.2%)" "GO:0008053 (9.6%) GO:0051646 (9%) GO:0046039 (2%)" "GO:0005741 (7.9%) GO:0016020 (2.4%) GO:0005886 (2.2%)" "GO:0003924 (9.6%) GO:0005525 (9.6%) GO:0005524 (2.5%)" "mitochondrial fusion (9.6%) mitochondrion localization (9%) GTP metabolic process (2%)" "mitochondrial outer membrane (7.9%) membrane (2.4%) plasma membrane (2.2%)" "GTPase activity (9.6%) GTP binding (9.6%) ATP binding (2.5%)" "IPR027417 (11.8%) IPR027094 (9.2%) IPR006884 (9.1%)" "P-loop containing nucleoside triphosphate hydrolase (11.8%) Mitofusin family (9.2%) Fzo/mitofusin HR2 domain (9.1%)" LYYQDEAGNWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.5%) "GO:0016787 (50%) GO:0016798 (1.5%)" carbohydrate metabolic process (48.5%) "hydrolase activity (50%) hydrolase activity, acting on glycosyl bonds (1.5%)" "IPR008979 (16.7%) IPR012878 (16.7%) IPR049046 (16.7%)" "Galactose-binding-like domain superfamily (16.7%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.7%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.7%)" GDLWYPFNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.15 (100%) endo-polygalacturonase (100%) GO:0005975 (41.4%) "GO:0004650 (41.4%) GO:0004557 (15.7%) GO:0016829 (1.4%)" carbohydrate metabolic process (41.4%) "polygalacturonase activity (41.4%) alpha-galactosidase activity (15.7%) lyase activity (1.4%)" "IPR000743 (20.9%) IPR006626 (20.9%) IPR051801 (20.9%)" "Glycoside hydrolase, family 28 (20.9%) Parallel beta-helix repeat (20.9%) Glycosyl_Hydrolase_28_Enzymes (20.9%)" EEGVVLQYVTCEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" VKEFDVGLDLSFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" YDPNTPLEETLQAMVDLVK Pseudomonadati Bacteria Pseudomonadati GO:0051596 (50%) GO:0016491 (50%) methylglyoxal catabolic process (50%) oxidoreductase activity (50%) "IPR005399 (33.8%) IPR023210 (33.8%) IPR036812 (32.4%)" "Potassium channel, voltage-dependent, beta subunit, KCNAB-related (33.8%) NADP-dependent oxidoreductase domain (33.8%) NAD(P)-dependent oxidoreductase domain superfamily (32.4%)" YYFTFPWVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.4 (100%) cellulase (100%) "GO:0045493 (23.8%) GO:0030245 (20.5%)" "GO:0004553 (23.2%) GO:0030246 (23.2%) GO:0016829 (8.6%)" "xylan catabolic process (23.8%) cellulose catabolic process (20.5%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (23.2%) carbohydrate binding (23.2%) lyase activity (8.6%)" "IPR006710 (13.9%) IPR052176 (13.9%) IPR005084 (13.5%)" "Glycoside hydrolase, family 43 (13.9%) Glycosyl Hydrolase Family 43 Enzymes (13.9%) Carbohydrate binding module family 6 (13.5%)" AWGFEYK root "2.2.1.7 (98%) 2.1.1.72 (2%)" "1-deoxy-D-xylulose-5-phosphate synthase (98%) site-specific DNA-methyltransferase (adenine-specific) (2%)" "GO:0032259 (22%) GO:0016114 (7.2%) GO:0019288 (7.2%)" "GO:0005829 (7.2%) GO:0044384 (0.3%) GO:0009279 (0.2%)" "GO:0008168 (18.8%) GO:0003676 (10.4%) GO:0008661 (7.2%)" "methylation (22%) terpenoid biosynthetic process (7.2%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (7.2%)" "cytosol (7.2%) host outer membrane (0.3%) cell outer membrane (0.2%)" "methyltransferase activity (18.8%) nucleic acid binding (10.4%) 1-deoxy-D-xylulose-5-phosphate synthase activity (7.2%)" "IPR007757 (23%) IPR029063 (21.8%) IPR002052 (10.7%)" "MT-A70-like (23%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (21.8%) DNA methylase, N-6 adenine-specific, conserved site (10.7%)" QYLFDHLWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR012393 (14.5%) IPR028204 (14.5%) IPR005151 (13.8%)" "Tricorn protease (14.5%) Tricorn protease C1 domain (14.5%) Tail specific protease (13.8%)" LLLSLLK root "7.1.1.- (18.9%) 2.7.11.1 (8%) 3.6.4.13 (5.2%)" "Hydron translocation or charge separation linked to oxidoreductase reactions (18.9%) non-specific serine/threonine protein kinase (8%) RNA helicase (5.2%)" "GO:0015031 (1.5%) GO:0016192 (1.4%) GO:0007030 (1.3%)" "GO:0016020 (7.1%) GO:0005886 (5.5%) GO:0005737 (2.1%)" "GO:0005524 (3.1%) GO:0003677 (1.3%) GO:0008270 (1.1%)" "protein transport (1.5%) vesicle-mediated transport (1.4%) Golgi organization (1.3%)" "membrane (7.1%) plasma membrane (5.5%) cytoplasm (2.1%)" "ATP binding (3.1%) DNA binding (1.3%) zinc ion binding (1.1%)" "IPR027417 (2.4%) IPR016024 (1.7%) IPR011989 (1.3%)" "P-loop containing nucleoside triphosphate hydrolase (2.4%) Armadillo-type fold (1.7%) Armadillo-like helical (1.3%)" THSFAAELQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" AREYMVDLYSHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (18.3%) GO:0006096 (11.3%) GO:0030388 (11.3%)" "GO:0008270 (29.6%) GO:0016832 (16.9%) GO:0004332 (12.7%)" "carbohydrate metabolic process (18.3%) glycolytic process (11.3%) fructose 1,6-bisphosphate metabolic process (11.3%)" "zinc ion binding (29.6%) aldehyde-lyase activity (16.9%) fructose-bisphosphate aldolase activity (12.7%)" "IPR000771 (29.6%) IPR013785 (29.6%) IPR050246 (29.6%)" "Fructose-bisphosphate aldolase, class-II (29.6%) Aldolase-type TIM barrel (29.6%) Class II Fructose-bisphosphate Aldolase (29.6%)" VEVVLLPLR root "2.1.1.- (77.8%) 2.5.1.61 (22.2%)" "Methyltransferases (77.8%) hydroxymethylbilane synthase (22.2%)" "GO:0032259 (31.3%) GO:0006782 (2.4%)" GO:0005737 (2.4%) "GO:0008171 (31.3%) GO:0008757 (30.1%) GO:0004418 (2.4%)" "methylation (31.3%) protoporphyrinogen IX biosynthetic process (2.4%)" cytoplasm (2.4%) "O-methyltransferase activity (31.3%) S-adenosylmethionine-dependent methyltransferase activity (30.1%) hydroxymethylbilane synthase activity (2.4%)" "IPR002935 (29.5%) IPR029063 (28.4%) IPR050362 (28.4%)" "Class I-like SAM-dependent O-methyltransferase (29.5%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (28.4%) Cation-dependent O-methyltransferase (28.4%)" LTPMATNLQFVFYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.4%) GO:0016787 (48.6%) membrane (51.4%) hydrolase activity (48.6%) "IPR000560 (51.4%) IPR029033 (48.6%)" "Histidine phosphatase superfamily, clade-2 (51.4%) Histidine phosphatase superfamily (48.6%)" VLNLNLEHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000270 (33.3%) GO:0016020 (33.3%) GO:0008933 (33.3%) peptidoglycan metabolic process (33.3%) membrane (33.3%) peptidoglycan lytic transglycosylase activity (33.3%) "IPR018392 (21.1%) IPR000189 (20.2%) IPR008258 (20.2%)" "LysM domain (21.1%) Prokaryotic transglycosylase, active site (20.2%) Transglycosylase SLT domain 1 (20.2%)" EQGPVQAHLADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (20.3%) IPR002469 (20.3%) IPR011659 (20.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (20.3%) Dipeptidylpeptidase IV, N-terminal domain (20.3%) WD40-like beta-propeller (20.3%)" LDYLADLLGLSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "5.6.2.4 (86.9%) 3.6.4.12 (13.1%)" "DNA 3'-5' helicase (86.9%) DNA helicase (13.1%)" "GO:0006281 (9.3%) GO:0006310 (9.3%) GO:0000724 (0.8%)" "GO:0005737 (10.1%) GO:0030894 (8.4%) GO:0043590 (8.4%)" "GO:0005524 (10.4%) GO:0043138 (10.4%) GO:0016787 (10.3%)" "DNA repair (9.3%) DNA recombination (9.3%) double-strand break repair via homologous recombination (0.8%)" "cytoplasm (10.1%) replisome (8.4%) bacterial nucleoid (8.4%)" "ATP binding (10.4%) 3'-5' DNA helicase activity (10.4%) hydrolase activity (10.3%)" "IPR014016 (14%) IPR014017 (13.9%) IPR001650 (13.7%)" "UvrD-like helicase, ATP-binding domain (14%) UvrD-like DNA helicase, C-terminal (13.9%) Helicase, C-terminal domain-like (13.7%)" LVHGTDQAPPYTYVASYLWAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) KGENLLTEWLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015969 (44.4%) GO:0005886 (44.4%) GO:0016787 (11.1%) guanosine tetraphosphate metabolic process (44.4%) plasma membrane (44.4%) hydrolase activity (11.1%) "IPR002912 (9.2%) IPR003607 (9.2%) IPR004095 (9.2%)" "ACT domain (9.2%) HD/PDEase domain (9.2%) TGS (9.2%)" PADADETTVCWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.2.1.1 (94.7%) 2.2.1.- (5.3%)" "transketolase (94.7%) Transketolases and transaldolases (5.3%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005475 (12.8%) IPR009014 (12.8%) IPR020826 (12.8%)" "Transketolase-like, pyrimidine-binding domain (12.8%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.8%) Transketolase binding site (12.8%)" NLLVANVFNATSHWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005737 (35.6%) GO:0016020 (28.7%)" GO:0016787 (35.6%) "cytoplasm (35.6%) membrane (28.7%)" hydrolase activity (35.6%) "IPR004843 (20.3%) IPR032285 (20.3%) IPR032288 (20.3%)" "Calcineurin-like, phosphoesterase domain (20.3%) Calcineurin-like phosphoesterase, N-terminal (20.3%) Calcineurin-like phosphoesterase, C-terminal (20.3%)" KAEAEALALQK Pseudomonadati Bacteria Pseudomonadati GO:0006508 (3%) "GO:0005886 (45.5%) GO:0098552 (45.5%)" "GO:0008233 (3%) GO:0004672 (1%) GO:0005524 (1%)" proteolysis (3%) "plasma membrane (45.5%) side of membrane (45.5%)" "peptidase activity (3%) protein kinase activity (1%) ATP binding (1%)" "IPR001107 (20.9%) IPR018080 (20.9%) IPR036013 (20.9%)" "Band 7 domain (20.9%) Band 7/stomatin-like, conserved site (20.9%) Band 7/SPFH domain superfamily (20.9%)" TMTEDPSAGYLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (37.1%) GO:0089702 (12.9%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (37.1%) undecaprenyl-phosphate glucose phosphotransferase activity (12.9%)" "IPR003362 (33.7%) IPR017475 (33.7%) IPR017473 (32.7%)" "Bacterial sugar transferase (33.7%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (33.7%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (32.7%)" PYVNTLTYLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (50%) GO:0005886 (50%) cell division (50%) plasma membrane (50%) "IPR003838 (33.3%) IPR004513 (33.3%) IPR040690 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) Cell division protein FtsX (33.3%) FtsX, extracellular domain (33.3%)" LNADLVVATDPDADR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25.2%) GO:0006166 (25.2%)" "GO:0008973 (25.2%) GO:0000287 (24.3%)" "carbohydrate metabolic process (25.2%) purine ribonucleoside salvage (25.2%)" "phosphopentomutase activity (25.2%) magnesium ion binding (24.3%)" "IPR005846 (14.9%) IPR005844 (14.4%) IPR005845 (14.4%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.4%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.4%)" SPDDHLLLLDEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009166 (20%) GO:0030288 (20%) "GO:0000166 (20%) GO:0016788 (20%) GO:0046872 (20%)" nucleotide catabolic process (20%) outer membrane-bounded periplasmic space (20%) "nucleotide binding (20%) hydrolase activity, acting on ester bonds (20%) metal ion binding (20%)" "IPR004843 (16.9%) IPR006146 (16.9%) IPR006179 (16.9%)" "Calcineurin-like, phosphoesterase domain (16.9%) 5'-Nucleotidase, conserved site (16.9%) 5'-Nucleotidase/apyrase (16.9%)" QLLEWLAQECENAANDLDER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.9%) IPR033985 (31.8%) IPR012944 (28.2%)" "Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (31.8%) RagB/SusD domain (28.2%)" TLVGEDPAFYTLLDEVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (23.9%) GO:0030313 (22.2%) "GO:0016209 (26.5%) GO:0016491 (26.5%) GO:0004601 (0.9%)" cytochrome complex assembly (23.9%) cell envelope (22.2%) "antioxidant activity (26.5%) oxidoreductase activity (26.5%) peroxidase activity (0.9%)" "IPR000866 (20.8%) IPR013766 (20.8%) IPR050553 (20.8%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.8%) Thioredoxin domain (20.8%) Thioredoxin family ResA/DsbE subfamily (20.8%)" LTQVSGEGAHMVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR022385 (18.8%) IPR050708 (18.8%) IPR003284 (12.5%)" "Rhs repeat-associated core (18.8%) Type VI secretion system VgrG/RHS (18.8%) Salmonella virulence plasmid 65kDa B protein (12.5%)" SFDEVQETFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) HSFYYGVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (17.1%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (17.1%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" VELTLNTK root "2.7.7.18 (50%) 3.4.24.- (50%)" "nicotinate-nucleotide adenylyltransferase (50%) Metalloendopeptidases (50%)" "GO:0015031 (21.1%) GO:0051205 (21.1%) GO:0006524 (1.6%)" "GO:0005886 (21.1%) GO:0005829 (2%) GO:0016020 (1.6%)" "GO:0032977 (21.1%) GO:0043565 (1.6%) GO:0003723 (0.4%)" "protein transport (21.1%) protein insertion into membrane (21.1%) alanine catabolic process (1.6%)" "plasma membrane (21.1%) cytosol (2%) membrane (1.6%)" "membrane insertase activity (21.1%) sequence-specific DNA binding (1.6%) RNA binding (0.4%)" "IPR001708 (13.7%) IPR019998 (13.7%) IPR028053 (13.7%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (13.7%) Membrane insertase YidC (13.7%) Membrane insertase YidC, N-terminal (13.7%)" LLREDCNPNPNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR011990 (33.3%) IPR033985 (30.3%)" "RagB/SusD domain (36.4%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (30.3%)" PTVASCTPAALTAGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" LLSEEGYTDAQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (25.5%) IPR053227 (25.5%) IPR027417 (24.5%)" "NadR/Ttd14, AAA domain (25.5%) TRPL channel trafficking regulator (25.5%) P-loop containing nucleoside triphosphate hydrolase (24.5%)" GFLENSQVWMSHGDTLTALPDDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.4%) "GO:0003921 (32.4%) GO:0005524 (32.4%) GO:0016740 (2.7%)" cytosol (32.4%) "GMP synthase activity (32.4%) ATP binding (32.4%) transferase activity (2.7%)" "IPR004739 (13.2%) IPR017926 (13.2%) IPR029062 (13.2%)" "GMP synthase, glutamine amidotransferase (13.2%) Glutamine amidotransferase (13.2%) Class I glutamine amidotransferase-like (13.2%)" DFELLFGK root 2.3.1.222 (100%) phosphate propanoyltransferase (100%) "GO:0009166 (15.9%) GO:0051144 (1%) GO:0006979 (0.5%)" "GO:0030288 (15.9%) GO:0016020 (1.5%) GO:0005634 (0.5%)" "GO:0046872 (19%) GO:0000166 (15.9%) GO:0016788 (15.9%)" "nucleotide catabolic process (15.9%) 1,2-propanediol catabolic process (1%) response to oxidative stress (0.5%)" "outer membrane-bounded periplasmic space (15.9%) membrane (1.5%) nucleus (0.5%)" "metal ion binding (19%) nucleotide binding (15.9%) hydrolase activity, acting on ester bonds (15.9%)" "IPR004843 (13.7%) IPR006146 (13.7%) IPR006179 (13.7%)" "Calcineurin-like, phosphoesterase domain (13.7%) 5'-Nucleotidase, conserved site (13.7%) 5'-Nucleotidase/apyrase (13.7%)" LREEVAMQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.1%) GO:0005829 (33.9%) GO:0008861 (33.9%) glucose metabolic process (32.1%) cytosol (33.9%) formate C-acetyltransferase activity (33.9%) "IPR004184 (20.7%) IPR050244 (20.7%) IPR001150 (19.6%)" "Pyruvate formate lyase domain (20.7%) Autonomous Glycyl Radical Cofactor (20.7%) Glycine radical domain (19.6%)" EYGLNVSHVVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016301 (96.6%) GO:0047590 (3.4%)" "kinase activity (96.6%) 5-dehydro-2-deoxygluconokinase activity (3.4%)" "IPR011611 (34.1%) IPR052700 (34.1%) IPR029056 (31.8%)" "Carbohydrate kinase PfkB (34.1%) Carbohydrate kinase PfkB-like (34.1%) Ribokinase-like (31.8%)" GETVSSNLMTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GWHSATLSENGQYVFDNYSTPTVPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.4%) IPR002469 (25.4%) IPR050278 (25.4%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.4%) Dipeptidylpeptidase IV, N-terminal domain (25.4%) Serine protease S9B/DPPIV (25.4%)" GYVLSVVANKTESTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" FPPFLQVLEDLTGNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (25.5%) IPR053227 (25.5%) IPR027417 (24.5%)" "NadR/Ttd14, AAA domain (25.5%) TRPL channel trafficking regulator (25.5%) P-loop containing nucleoside triphosphate hydrolase (24.5%)" EDLLEGFK root "2.7.7.18 (25%) 2.3.1.47 (16.7%) 4.4.1.13 (12.5%)" "nicotinate-nucleotide adenylyltransferase (25%) 8-amino-7-oxononanoate synthase (16.7%) cysteine-S-conjugate beta-lyase (12.5%)" "GO:0006355 (17.9%) GO:0019346 (0.5%) GO:0009435 (0.4%)" "GO:0005829 (18%) GO:0032993 (17.9%) GO:0005737 (1.1%)" "GO:0000156 (17.9%) GO:0000976 (17.9%) GO:0030170 (0.8%)" "regulation of DNA-templated transcription (17.9%) transsulfuration (0.5%) NAD+ biosynthetic process (0.4%)" "cytosol (18%) protein-DNA complex (17.9%) cytoplasm (1.1%)" "phosphorelay response regulator activity (17.9%) transcription cis-regulatory region binding (17.9%) pyridoxal phosphate binding (0.8%)" "IPR001789 (15.6%) IPR011006 (15.5%) IPR039420 (15.5%)" "Signal transduction response regulator, receiver domain (15.6%) CheY-like superfamily (15.5%) Transcriptional regulatory protein WalR-like (15.5%)" LFFDDVNEMVAEVLDNTTSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.99.17 (100%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (100%) GO:0002099 (34.4%) GO:0005737 (31.3%) GO:0051075 (34.4%) tRNA wobble guanine modification (34.4%) cytoplasm (31.3%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (34.4%) "IPR003699 (26.8%) IPR036100 (24.4%) IPR042118 (24.4%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA (26.8%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily (24.4%) QueA, domain 1 (24.4%)" NLVLGYDFPQEWFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (11.8%) GO:0009279 (76.5%) GO:0015344 (11.8%) siderophore transmembrane transport (11.8%) cell outer membrane (76.5%) siderophore uptake transmembrane transporter activity (11.8%) "IPR000531 (14.4%) IPR036942 (14.4%) IPR039426 (14.4%)" "TonB-dependent receptor-like, beta-barrel (14.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.4%) TonB-dependent receptor-like (14.4%)" NYDKELDLNNFQLEALGAGAYVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" RLFTVNR root "1.17.4.1 (50%) 5.3.3.17 (50%)" "ribonucleoside-diphosphate reductase (50%) trans-2,3-dihydro-3-hydroxyanthranilate isomerase (50%)" "GO:0006412 (16.7%) GO:0080120 (1%) GO:0071709 (1%)" "GO:0005840 (16.7%) GO:1990904 (16.6%) GO:0016020 (1.7%)" "GO:0003735 (16.7%) GO:0000049 (15.4%) GO:0003723 (1.3%)" "translation (16.7%) CAAX-box protein maturation (1%) membrane assembly (1%)" "ribosome (16.7%) ribonucleoprotein complex (16.6%) membrane (1.7%)" "structural constituent of ribosome (16.7%) tRNA binding (15.4%) RNA binding (1.3%)" "IPR001848 (18.2%) IPR027486 (18.2%) IPR036838 (18.2%)" "Small ribosomal subunit protein uS10 (18.2%) Small ribosomal subunit protein uS10 domain (18.2%) Small ribosomal subunit protein uS10 domain superfamily (18.2%)" VNSGDCVVLTHEGPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.2%) GO:0009099 (16.2%)" GO:0005829 (16.9%) "GO:0000287 (16.2%) GO:0004160 (16.2%) GO:0051537 (16.2%)" "isoleucine biosynthetic process (16.2%) L-valine biosynthetic process (16.2%)" cytosol (16.9%) "magnesium ion binding (16.2%) dihydroxy-acid dehydratase activity (16.2%) 2 iron, 2 sulfur cluster binding (16.2%)" "IPR000581 (16.8%) IPR020558 (16.8%) IPR037237 (16.8%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.8%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.8%) IlvD/EDD, N-terminal domain (16.8%)" EGRVDGLANVNDESGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (13%) IPR050220 (13%) IPR005743 (12.7%)" "DNA topoisomerase, type IIA, domain A (13%) Type II DNA Topoisomerases (13%) DNA gyrase, subunit A (12.7%)" EGGPLYNAFLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FLAGYPGK root "4.-.-.- (50%) 3.2.1.- (25%) 3.2.1.22 (25%)" "Lyases (50%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (25%) alpha-galactosidase (25%)" GO:0008616 (2%) "GO:0030246 (46.1%) GO:0016798 (44.1%) GO:0016787 (2.9%)" tRNA queuosine(34) biosynthetic process (2%) "carbohydrate binding (46.1%) hydrolase activity, acting on glycosyl bonds (44.1%) hydrolase activity (2.9%)" "IPR029483 (13%) IPR052720 (13%) IPR019563 (12.7%)" "Glycosyl-hydrolase 97, C-terminal oligomerisation domain (13%) Glycosyl Hydrolase Family 97 (13%) Glycosyl-hydrolase 97, catalytic domain (12.7%)" NVQAQETESLNLR Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) "IPR018704 (33.8%) IPR019734 (33.8%) IPR011990 (32.4%)" "Ancillary SecYEG translocon subunit/Cell division coordinator CpoB, TPR domain (33.8%) Tetratricopeptide repeat (33.8%) Tetratricopeptide-like helical domain superfamily (32.4%)" TGFSQNYDLSVSHANDKHSAMFSLGYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GTYVNLGLGSHFYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.9%) GO:0006811 (3.1%)" GO:0009279 (50%) "iron ion transport (46.9%) monoatomic ion transport (3.1%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" LKPLQDVGLGYLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) "GO:0006289 (12.4%) GO:0006281 (0.1%)" "GO:0005737 (12.4%) GO:0009380 (12.4%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" "nucleotide-excision repair (12.4%) DNA repair (0.1%)" "cytoplasm (12.4%) excinuclease repair complex (12.4%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (15.9%) IPR004602 (15.7%) IPR027417 (15.6%)" "ABC transporter-like, ATP-binding domain (15.9%) UvrABC system subunit A (15.7%) P-loop containing nucleoside triphosphate hydrolase (15.6%)" LSGTLDFYWNTTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006826 (31%) GO:0009279 (69%) iron ion transport (31%) cell outer membrane (69%) "IPR000531 (12.9%) IPR023996 (12.9%) IPR036942 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%) TonB-dependent receptor-like, beta-barrel domain superfamily (12.9%)" NGDGCFYANFKPDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.11.1 (100%) non-specific serine/threonine protein kinase (100%) "GO:0120147 (97.1%) GO:0016301 (2.9%)" "formylglycine-generating oxidase activity (97.1%) kinase activity (2.9%)" "IPR005532 (25.8%) IPR051043 (25.8%) IPR016187 (24.2%)" "Sulfatase-modifying factor enzyme-like domain (25.8%) Sulfatase Modifying Factor and Kinase (25.8%) C-type lectin fold (24.2%)" AVYNLEEFDFSSFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" VVYAGPSSEYSTTDKAEQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006289 (12.3%) GO:0006281 (0.4%)" "GO:0005737 (12.6%) GO:0009380 (12.3%)" "GO:0003677 (12.6%) GO:0004518 (12.6%) GO:0005524 (12.6%)" "nucleotide-excision repair (12.3%) DNA repair (0.4%)" "cytoplasm (12.6%) excinuclease repair complex (12.3%)" "DNA binding (12.6%) nuclease activity (12.6%) ATP binding (12.6%)" "IPR003439 (16.9%) IPR004602 (16.9%) IPR041102 (16.9%)" "ABC transporter-like, ATP-binding domain (16.9%) UvrABC system subunit A (16.9%) UvrA, interaction domain (16.9%)" LTLLEQLFGGGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.26.5 (100%) ribonuclease P (100%) GO:0001682 (29.4%) GO:0030677 (5.9%) "GO:0000049 (29.4%) GO:0004526 (29.4%) GO:0042781 (5.9%)" tRNA 5'-leader removal (29.4%) ribonuclease P complex (5.9%) "tRNA binding (29.4%) ribonuclease P activity (29.4%) 3'-tRNA processing endoribonuclease activity (5.9%)" "IPR000100 (25.9%) IPR020539 (25.9%) IPR014721 (24.1%)" "Ribonuclease P (25.9%) Ribonuclease P, conserved site (25.9%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (24.1%)" NAFHDVHAFDGFVCYDLPVANPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR010870 (50%) IPR023614 (50%)" "Phosphate-selective porin O/P (50%) Porin domain superfamily (50%)" NLHVTVTDAGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006298 (14.7%) GO:0032300 (14.7%) "GO:0016887 (14.7%) GO:0140664 (14.7%) GO:0005524 (14.1%)" mismatch repair (14.7%) mismatch repair complex (14.7%) "ATP hydrolysis activity (14.7%) ATP-dependent DNA damage sensor activity (14.7%) ATP binding (14.1%)" "IPR038973 (8.9%) IPR002099 (8.6%) IPR013507 (8.6%)" "DNA mismatch repair protein MutL/Mlh/Pms-like (8.9%) DNA mismatch repair protein MutL/Mlh/PMS (8.6%) DNA mismatch repair protein, S5 domain 2-like (8.6%)" MVYVELEEGAKLEDVTAELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25.4%) IPR010190 (25.4%) IPR032094 (25.4%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.4%) Diaminopimelate dehydrogenase, Ddh (25.4%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25.4%)" MNQLLLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027417 (40%) IPR041685 (30%) IPR051396 (30%)" "P-loop containing nucleoside triphosphate hydrolase (40%) Endonuclease GajA/Old nuclease/RecF-like, AAA domain (30%) Bacterial Antiviral Defense Nuclease (30%)" YLLDFSLR Pseudomonadati Bacteria Pseudomonadati "GO:0006508 (10.6%) GO:0006099 (3%)" "GO:0009279 (50%) GO:0016020 (13.6%) GO:0005886 (3%)" "GO:0008236 (10.6%) GO:0009055 (3%) GO:0046872 (3%)" "proteolysis (10.6%) tricarboxylic acid cycle (3%)" "cell outer membrane (50%) membrane (13.6%) plasma membrane (3%)" "serine-type peptidase activity (10.6%) electron transfer activity (3%) metal ion binding (3%)" "IPR023996 (13.3%) IPR039426 (13.3%) IPR036942 (12.4%)" "TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent receptor-like (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (12.4%)" LTLPEQFGMEPTSTLAESNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.6%) IPR012910 (14.6%) IPR023996 (14.6%)" "Carboxypeptidase-like, regulatory domain superfamily (14.6%) TonB-dependent receptor, plug domain (14.6%) TonB-dependent outer membrane protein, SusC/RagA (14.6%)" YGWQVELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.4%) IPR041542 (20.4%) IPR051795 (20.4%)" "Glycoside hydrolase, family 43 (20.4%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.4%) Glycosyl Hydrolase Family 43 (20.4%)" LLNYQGLQLNLDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (16.7%) IPR001867 (16.7%) IPR011006 (16.7%)" "Signal transduction response regulator, receiver domain (16.7%) OmpR/PhoB-type DNA-binding domain (16.7%) CheY-like superfamily (16.7%)" HLLDLDEAMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14%) GO:0006221 (13.5%) GO:0006526 (12.9%)" GO:0005737 (14%) "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (14%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (13.5%) L-arginine biosynthetic process (12.9%)" cytoplasm (14%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (14%)" "IPR005480 (11%) IPR005479 (10.5%) IPR011761 (10.5%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (11%) Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%)" FSEEEAFSTPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LKLPEGYYYNYGGEFENLQSATQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (34%) IPR004763 (34%) IPR027463 (31.9%)" "Acriflavin resistance protein (34%) Cation efflux system CusA-like (34%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.9%)" GTVQEVLYQLLGGLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20%) GO:0006183 (20%)" "GO:0000166 (20%) GO:0003938 (20%) GO:0046872 (20%)" "GMP biosynthetic process (20%) GTP biosynthetic process (20%)" "nucleotide binding (20%) IMP dehydrogenase activity (20%) metal ion binding (20%)" "IPR000644 (17%) IPR001093 (17%) IPR005990 (17%)" "CBS domain (17%) IMP dehydrogenase/GMP reductase (17%) Inosine-5'-monophosphate dehydrogenase (17%)" YLNNPQGNSPDSDSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR025684 (50%) IPR026377 (50%)" "Gliding motility protein SprA N-terminal domain (50%) Cell surface SprA (50%)" NLNVGGGLGLDYNHPNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (34.2%) "GO:0008836 (34.2%) GO:0030170 (31.6%)" lysine biosynthetic process via diaminopimelate (34.2%) "diaminopimelate decarboxylase activity (34.2%) pyridoxal phosphate binding (31.6%)" "IPR022643 (14.8%) IPR002986 (14.3%) IPR009006 (14.3%)" "Orn/DAP/Arg decarboxylase 2, C-terminal (14.8%) Diaminopimelate decarboxylase, LysA (14.3%) Alanine racemase/group IV decarboxylase, C-terminal (14.3%)" YFHLGGDECPK root 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" "GO:0016020 (24.8%) GO:0009279 (0.2%)" GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" "membrane (24.8%) cell outer membrane (0.2%)" beta-N-acetylhexosaminidase activity (25%) "IPR015883 (16.7%) IPR025705 (16.7%) IPR017853 (16.4%)" "Glycoside hydrolase family 20, catalytic domain (16.7%) Beta-hexosaminidase (16.7%) Glycoside hydrolase superfamily (16.4%)" ALGLAHHLLGVQCNNWSEYMYSNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.7%) IPR015883 (17.7%) IPR025705 (17.7%)" "PA14 domain (17.7%) Glycoside hydrolase family 20, catalytic domain (17.7%) Beta-hexosaminidase (17.7%)" NLLGSNLDYER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043741 (100%) Family of unknown function DUF5686 (100%) LFFLEVMGR root "2.7.1.11 (99%) 1.17.7.4 (1%)" "6-phosphofructokinase (99%) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (1%)" "GO:0006002 (9%) GO:0030388 (9%) GO:0061621 (9%)" "GO:0005945 (9%) GO:0005737 (0%) GO:0012505 (0%)" "GO:0003872 (9%) GO:0005524 (9%) GO:0046872 (9%)" "fructose 6-phosphate metabolic process (9%) fructose 1,6-bisphosphate metabolic process (9%) canonical glycolysis (9%)" "6-phosphofructokinase complex (9%) cytoplasm (0%) endomembrane system (0%)" "6-phosphofructokinase activity (9%) ATP binding (9%) metal ion binding (9%)" "IPR000023 (16.7%) IPR022953 (16.7%) IPR035966 (16.7%)" "Phosphofructokinase domain (16.7%) ATP-dependent 6-phosphofructokinase (16.7%) Phosphofructokinase superfamily (16.7%)" ELEYEVVR root "6.3.4.16 (30.1%) 6.3.5.5 (26.3%) 2.1.3.2 (17.4%)" "carbamoyl-phosphate synthase (ammonia) (30.1%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (26.3%) aspartate carbamoyltransferase (17.4%)" "GO:0006541 (9%) GO:0006207 (7.9%) GO:0006526 (7.1%)" "GO:0005951 (5.3%) GO:0005634 (1.9%) GO:0005737 (1.9%)" "GO:0005524 (9.9%) GO:0004088 (9.9%) GO:0046872 (9.6%)" "glutamine metabolic process (9%) 'de novo' pyrimidine nucleobase biosynthetic process (7.9%) L-arginine biosynthetic process (7.1%)" "carbamoyl-phosphate synthase complex (5.3%) nucleus (1.9%) cytoplasm (1.9%)" "ATP binding (9.9%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (9.9%) metal ion binding (9.6%)" "IPR005479 (5.5%) IPR011761 (5.5%) IPR005483 (5.5%)" "Carbamoyl phosphate synthase, ATP-binding domain (5.5%) ATP-grasp fold (5.5%) Carbamoyl phosphate synthase, CPSase domain (5.5%)" LVSFNSGK root "3.4.13.18 (97.2%) 2.7.10.1 (2.8%)" "cytosol non-specific dipeptidase (97.2%) receptor protein-tyrosine kinase (2.8%)" "GO:0006508 (23.3%) GO:0000160 (1.8%) GO:0072318 (0.6%)" "GO:0005829 (23.3%) GO:0005737 (0.6%) GO:0016020 (0.6%)" "GO:0070573 (23.3%) GO:0046872 (21.5%) GO:0008081 (1.8%)" "proteolysis (23.3%) phosphorelay signal transduction system (1.8%) clathrin coat disassembly (0.6%)" "cytosol (23.3%) cytoplasm (0.6%) membrane (0.6%)" "metallodipeptidase activity (23.3%) metal ion binding (21.5%) phosphoric diester hydrolase activity (1.8%)" "IPR001160 (26.8%) IPR002933 (24.6%) IPR011650 (21.8%)" "Peptidase M20C, Xaa-His dipeptidase (26.8%) Peptidase M20 (24.6%) Peptidase M20, dimerisation domain (21.8%)" VLVADLGCVLYDGDQSFTLKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002547 (7.8%) IPR004532 (7.8%) IPR005121 (7.8%)" "tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%) Ferrodoxin-fold anticodon-binding domain (7.8%)" HGGFYLGTLGGVAAVLSQSSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (25%) "GO:0046872 (25%) GO:0051539 (25%) GO:0004333 (24.7%)" tricarboxylic acid cycle (25%) "metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%) fumarate hydratase activity (24.7%)" "IPR004646 (17.9%) IPR004647 (17.9%) IPR051208 (17.9%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (17.9%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (17.9%) Class-I Fumarase/Tartrate Dehydratase (17.9%)" GLGFGGGPWFVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.8.1.13 (100%) tRNA-uridine 2-sulfurtransferase (100%) "GO:0008033 (18.4%) GO:0032259 (13.2%)" "GO:0000049 (18.4%) GO:0005524 (18.4%) GO:0008168 (13.2%)" "tRNA processing (18.4%) methylation (13.2%)" "tRNA binding (18.4%) ATP binding (18.4%) methyltransferase activity (13.2%)" "IPR014729 (16.9%) IPR023382 (16.9%) IPR046884 (16.9%)" "Rossmann-like alpha/beta/alpha sandwich fold (16.9%) tRNA-specific 2-thiouridylase MnmA-like, central domain superfamily (16.9%) tRNA-specific 2-thiouridylase MnmA-like, central domain (16.9%)" GHKEYLETCLGEGAK Pseudomonadati Bacteria Pseudomonadati "GO:0016491 (33.3%) GO:0046872 (33.3%) GO:0051287 (33.3%)" "oxidoreductase activity (33.3%) metal ion binding (33.3%) NAD binding (33.3%)" IPR005255 (100%) PdxA family (100%) MVLPFSLSGDDVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR018392 (35.1%) IPR028082 (32.5%) IPR036779 (32.5%)" "LysM domain (35.1%) Periplasmic binding protein-like I (32.5%) LysM domain superfamily (32.5%)" ALTQLVGK root "2.7.1.56 (50%) 5.1.3.2 (50%)" "1-phosphofructokinase (50%) UDP-glucose 4-epimerase (50%)" "GO:0006412 (18.3%) GO:0015979 (2.4%) GO:0007155 (1.2%)" "GO:0022627 (18.3%) GO:0030089 (2.4%) GO:0005829 (1.2%)" "GO:0003735 (18.3%) GO:0019843 (17.1%) GO:0016491 (2.4%)" "translation (18.3%) photosynthesis (2.4%) cell adhesion (1.2%)" "cytosolic small ribosomal subunit (18.3%) phycobilisome (2.4%) cytosol (1.2%)" "structural constituent of ribosome (18.3%) rRNA binding (17.1%) oxidoreductase activity (2.4%)" "IPR000589 (14.7%) IPR005290 (14.7%) IPR009068 (14.7%)" "Small ribosomal subunit protein uS15 (14.7%) Small ribosomal subunit protein uS15, bacteria (14.7%) uS15/NS1, RNA-binding domain superfamily (14.7%)" LENYGDLTRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033388 (42.1%) "GO:0050126 (42.1%) GO:0016746 (15.8%)" putrescine biosynthetic process from arginine (42.1%) "N-carbamoylputrescine amidase activity (42.1%) acyltransferase activity (15.8%)" "IPR003010 (33.3%) IPR036526 (33.3%) IPR050345 (33.3%)" "Carbon-nitrogen hydrolase (33.3%) Carbon-nitrogen hydrolase superfamily (33.3%) Aliphatic Amidase/Beta-Ureidopropionase (33.3%)" ALREEFNK root "1.3.5.1 (83.3%) 2.1.1.72 (12.5%) 6.3.4.19 (4.2%)" "succinate dehydrogenase (83.3%) site-specific DNA-methyltransferase (adenine-specific) (12.5%) tRNA(Ile)-lysidine synthetase (4.2%)" "GO:0009061 (14.7%) GO:0006298 (2.1%) GO:0009307 (2.1%)" "GO:0005886 (14.7%) GO:0000785 (0.7%) GO:0005576 (0.7%)" "GO:0009055 (14.7%) GO:0050660 (14.7%) GO:0000104 (13.3%)" "anaerobic respiration (14.7%) mismatch repair (2.1%) DNA restriction-modification system (2.1%)" "plasma membrane (14.7%) chromatin (0.7%) extracellular region (0.7%)" "electron transfer activity (14.7%) flavin adenine dinucleotide binding (14.7%) succinate dehydrogenase activity (13.3%)" "IPR015939 (11.1%) IPR030664 (11.1%) IPR037099 (11.1%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (11.1%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (11.1%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (11.1%)" ATLGEDVWTLENFNTYQWNGWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YTGVDGMATEGGGLELVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19.5%) "GO:0000155 (20.8%) GO:0003700 (20.1%) GO:0043565 (20.1%)" membrane (19.5%) "phosphorelay sensor kinase activity (20.8%) DNA-binding transcription factor activity (20.1%) sequence-specific DNA binding (20.1%)" "IPR003594 (7.9%) IPR003661 (7.9%) IPR036097 (7.9%)" "Histidine kinase/HSP90-like ATPase domain (7.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (7.9%)" DSYALVALNGGATFTDCPAGTYTDLVTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (74%) "GO:0016787 (20%) GO:0016829 (6%)" carbohydrate metabolic process (74%) "hydrolase activity (20%) lyase activity (6%)" "IPR013783 (24.7%) IPR017853 (24.7%) IPR006047 (23.4%)" "Immunoglobulin-like fold (24.7%) Glycoside hydrolase superfamily (24.7%) Glycosyl hydrolase family 13, catalytic domain (23.4%)" LYLFSFR root "1.7.1.13 (99.5%) 1.7.1.- (0.2%) 2.7.13.3 (0.1%)" "preQ1 synthase (99.5%) With NAD(+) or NADP(+) as acceptor (0.2%) histidine kinase (0.1%)" "GO:0008616 (24.2%) GO:0006400 (23.8%) GO:0055085 (0.3%)" "GO:0005737 (24.2%) GO:0016020 (0.6%) GO:0005886 (0.4%)" "GO:0033739 (24.2%) GO:0016787 (0.5%) GO:0016491 (0.1%)" "tRNA queuosine(34) biosynthetic process (24.2%) tRNA modification (23.8%) transmembrane transport (0.3%)" "cytoplasm (24.2%) membrane (0.6%) plasma membrane (0.4%)" "preQ1 synthase activity (24.2%) hydrolase activity (0.5%) oxidoreductase activity (0.1%)" "IPR016856 (24.2%) IPR029500 (24.2%) IPR050084 (24.2%)" "NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 (24.2%) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF (24.2%) NADPH-dependent 7-cyano-7-deazaguanine reductase (24.2%)" LAQDPLGK root GO:0016829 (100%) lyase activity (100%) "IPR003961 (26.2%) IPR033803 (26.2%) IPR013783 (23.8%)" "Fibronectin type III (26.2%) Golvesin/Xly, CBD-like (26.2%) Immunoglobulin-like fold (23.8%)" GLVMDFNGDDNVYDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" LFLVVEK root "4.1.1.19 (91.5%) 3.6.1.27 (2.7%) 2.7.13.3 (1.3%)" "arginine decarboxylase (91.5%) undecaprenyl-diphosphate phosphatase (2.7%) histidine kinase (1.3%)" "GO:0006527 (13.3%) GO:0008295 (13.3%) GO:0033388 (12.4%)" "GO:0005886 (3.3%) GO:0016020 (2.1%) GO:0005615 (0.9%)" "GO:0046872 (14.2%) GO:0008792 (13.3%) GO:0004497 (1.6%)" "L-arginine catabolic process (13.3%) spermidine biosynthetic process (13.3%) putrescine biosynthetic process from arginine (12.4%)" "plasma membrane (3.3%) membrane (2.1%) extracellular space (0.9%)" "metal ion binding (14.2%) arginine decarboxylase activity (13.3%) monooxygenase activity (1.6%)" "IPR002985 (8.7%) IPR022644 (8.7%) IPR022653 (8.6%)" "Arginine decarboxylase (8.7%) Orn/DAP/Arg decarboxylase 2, N-terminal (8.7%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (8.6%)" LLSVNTVDGFQGQER Bacteria Bacteria "3.6.1.- (50%) 3.6.4.12 (50%)" "In phosphorus-containing anhydrides (50%) DNA helicase (50%)" GO:0005694 (25%) "GO:0005524 (25%) GO:0016787 (25%) GO:0043139 (25%)" chromosome (25%) "ATP binding (25%) hydrolase activity (25%) 5'-3' DNA helicase activity (25%)" "IPR041677 (16.9%) IPR041679 (16.9%) IPR047187 (16.9%)" "DNA2/NAM7 helicase, helicase domain (16.9%) DNA2/NAM7 helicase-like, C-terminal (16.9%) Upf1-like, C-terminal helicase domain (16.9%)" LLSLKPAK root "6.1.1.5 (42.9%) 2.1.1.355 (28.6%) 2.3.2.30 (14.3%)" "isoleucine--tRNA ligase (42.9%) [histone H3]-lysine(9) N-trimethyltransferase (28.6%) L-ornithine N(alpha)-acyltransferase (14.3%)" "GO:0006428 (2%) GO:0000723 (1.4%) GO:0015833 (1.4%)" "GO:0016020 (25.2%) GO:0005886 (3.4%) GO:0005737 (2.7%)" "GO:0005524 (3.4%) GO:0008270 (3.4%) GO:0003682 (2.7%)" "isoleucyl-tRNA aminoacylation (2%) telomere maintenance (1.4%) peptide transport (1.4%)" "membrane (25.2%) plasma membrane (3.4%) cytoplasm (2.7%)" "ATP binding (3.4%) zinc ion binding (3.4%) chromatin binding (2.7%)" "IPR012505 (13.6%) IPR053154 (13.6%) IPR001680 (1.9%)" "YbbR-like (13.6%) Cyclic di-AMP regulator (13.6%) WD40 repeat (1.9%)" EFEGTVTALSGATGSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0055085 (50%) GO:0016020 (50%) transmembrane transport (50%) membrane (50%) "IPR043602 (37.3%) IPR050739 (37.3%) IPR032317 (25.3%)" "Unknown (37.3%) Membrane Fusion Protein (37.3%) Unknown (25.3%)" ETLALHPEYFDPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (18.9%) GO:0006096 (10.8%) GO:0030388 (10.8%)" "GO:0008270 (29.7%) GO:0016832 (17.6%) GO:0004332 (12.2%)" "carbohydrate metabolic process (18.9%) glycolytic process (10.8%) fructose 1,6-bisphosphate metabolic process (10.8%)" "zinc ion binding (29.7%) aldehyde-lyase activity (17.6%) fructose-bisphosphate aldolase activity (12.2%)" "IPR000771 (29.7%) IPR013785 (29.7%) IPR050246 (29.7%)" "Fructose-bisphosphate aldolase, class-II (29.7%) Aldolase-type TIM barrel (29.7%) Class II Fructose-bisphosphate Aldolase (29.7%)" RELLQVSR root "GO:0006412 (14.3%) GO:0015031 (4.8%) GO:0016192 (4.8%)" "GO:0022627 (14.3%) GO:0005765 (4.8%) GO:0016020 (4.8%)" "GO:0003735 (14.3%) GO:0003677 (2.4%) GO:0004672 (2.4%)" "translation (14.3%) protein transport (4.8%) vesicle-mediated transport (4.8%)" "cytosolic small ribosomal subunit (14.3%) lysosomal membrane (4.8%) membrane (4.8%)" "structural constituent of ribosome (14.3%) DNA binding (2.4%) protein kinase activity (2.4%)" "IPR001865 (9.4%) IPR005706 (9.4%) IPR018130 (9.4%)" "Small ribosomal subunit protein uS2 (9.4%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (9.4%) Small ribosomal subunit protein uS2, conserved site (9.4%)" AVLASPSAK root GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.2%) IPR009027 (14.2%) IPR020069 (14.2%)" "Large ribosomal subunit protein bL9 (14.2%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.2%) Large ribosomal subunit protein bL9, C-terminal (14.2%)" FGVHDLDLMAGAEQSHYHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR023996 (13.8%) IPR039426 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%) TonB-dependent receptor-like (13.8%)" HQVLLNATALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000184 (50%) IPR039910 (50%)" "Bacterial surface antigen (D15) (50%) Surface antigen D15-like (50%)" TSTAALPWLCVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (26.6%) GO:0030313 (25%) "GO:0016209 (23.4%) GO:0016491 (23.4%) GO:0004601 (1.6%)" cytochrome complex assembly (26.6%) cell envelope (25%) "antioxidant activity (23.4%) oxidoreductase activity (23.4%) peroxidase activity (1.6%)" "IPR025380 (24.7%) IPR036249 (24.7%) IPR050553 (24.7%)" "Domain of unknown function DUF4369 (24.7%) Thioredoxin-like superfamily (24.7%) Thioredoxin family ResA/DsbE subfamily (24.7%)" LLDPPLHEFVPHDLAGQQTMAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" DEMNAWSYQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (33.3%) IPR023996 (33.3%) IPR037066 (33.3%)" "TonB-dependent receptor, plug domain (33.3%) TonB-dependent outer membrane protein, SusC/RagA (33.3%) TonB-dependent receptor, plug domain superfamily (33.3%)" DVSSWLGNPMQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (49.6%) "GO:0003824 (31%) GO:0016787 (15.9%) GO:0004556 (3.5%)" carbohydrate metabolic process (49.6%) "catalytic activity (31%) hydrolase activity (15.9%) alpha-amylase activity (3.5%)" "IPR004300 (33.7%) IPR052046 (33.7%) IPR011330 (32.5%)" "Glycoside hydrolase family 57, N-terminal domain (33.7%) Glycosyl hydrolase family 57 (33.7%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.5%)" LDPQASAEALNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (52%) IPR011990 (48%)" "Tetratricopeptide repeat (52%) Tetratricopeptide-like helical domain superfamily (48%)" RGYSDSSMNTDEFVWNAQLSQGFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR041700 (100%) Outer membrane protein beta-barrel domain 3 (100%) TALATGVDDQTLLDEWCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" KAEPLMEAGQLVAYAQLAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.8%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.8%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" SQEQMLQATNAAAEAMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR032317 (51.7%) IPR011053 (48.3%)" "Unknown (51.7%) Single hybrid motif (48.3%)" NLGYYDGLVANPDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) TPTLLDDDCWLGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005829 (50%) GO:0008374 (50%) cytosol (50%) O-acyltransferase activity (50%) "IPR001451 (33.3%) IPR011004 (33.3%) IPR051159 (33.3%)" "Hexapeptide repeat (33.3%) Trimeric LpxA-like superfamily (33.3%) Hexapeptide-repeat containing acetyltransferases (33.3%)" MFEDMGVMKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.6%) GO:0004356 (51.4%) glutamine biosynthetic process (48.6%) glutamine synthetase activity (51.4%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" GQFLAAAK Bacteria Bacteria "1.4.1.13 (66.7%) 1.1.1.25 (8.3%) 3.4.11.1 (8.3%)" "glutamate synthase (NADPH) (66.7%) shikimate dehydrogenase (NADP(+)) (8.3%) leucyl aminopeptidase (8.3%)" "GO:0006935 (1.7%) GO:0071978 (1.7%) GO:0006351 (0.6%)" "GO:0005886 (2.3%) GO:0005737 (1.1%) GO:0005829 (0.6%)" "GO:0051536 (40.6%) GO:0016491 (36.6%) GO:0004355 (4.6%)" "chemotaxis (1.7%) bacterial-type flagellum-dependent swarming motility (1.7%) DNA-templated transcription (0.6%)" "plasma membrane (2.3%) cytoplasm (1.1%) cytosol (0.6%)" "iron-sulfur cluster binding (40.6%) oxidoreductase activity (36.6%) glutamate synthase (NADPH) activity (4.6%)" "IPR017927 (10.2%) IPR019480 (10.2%) IPR023753 (10.2%)" "FAD-binding domain, ferredoxin reductase-type (10.2%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (10.2%) FAD/NAD(P)-binding domain (10.2%)" DKDGNTLDDVLVSVFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.-.- (100%) Acting on acid anhydrides (100%) "GO:0002098 (14.3%) GO:0030488 (14.3%)" GO:0005829 (14.3%) "GO:0003924 (14.3%) GO:0005525 (14.3%) GO:0042802 (14.3%)" "tRNA wobble uridine modification (14.3%) tRNA methylation (14.3%)" cytosol (14.3%) "GTPase activity (14.3%) GTP binding (14.3%) identical protein binding (14.3%)" "IPR004520 (11.2%) IPR005225 (11.2%) IPR006073 (11.2%)" "tRNA modification GTPase MnmE (11.2%) Small GTP-binding domain (11.2%) GTP binding domain (11.2%)" NTVPGDQNLVTEEELLNNMTSSGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016301 (96.2%) GO:0047590 (3.8%)" "kinase activity (96.2%) 5-dehydro-2-deoxygluconokinase activity (3.8%)" "IPR011611 (34.2%) IPR052700 (34.2%) IPR029056 (31.6%)" "Carbohydrate kinase PfkB (34.2%) Carbohydrate kinase PfkB-like (34.2%) Ribokinase-like (31.6%)" NWLMQFDLHSMAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0004553 (85.7%) GO:0016787 (14.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (85.7%) hydrolase activity (14.3%)" "IPR053161 (35%) IPR008979 (32.5%) IPR054593 (32.5%)" "Ulvan-degrading glycoside hydrolase (35%) Galactose-binding-like domain superfamily (32.5%) Beta-mannosidase-like, galactose-binding domain-like (32.5%)" TLGCFTGTVFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (51.1%) GO:0022857 (48.9%) plasma membrane (51.1%) transmembrane transporter activity (48.9%) "IPR050375 (26.1%) IPR011701 (25%) IPR020846 (25%)" "Major Facilitator Superfamily TsgA-like (26.1%) Major facilitator superfamily (25%) Major facilitator superfamily domain (25%)" DYLGQVALFAAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (41.7%) IPR011990 (39.6%) IPR051685 (10.4%)" "Tetratricopeptide repeat (41.7%) Tetratricopeptide-like helical domain superfamily (39.6%) Ycf3/AcsC/BcsC/TPR Multifunctional (10.4%)" LEHLTYGVMLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) IPR017039 (100%) Virulence factor BrkB (100%) DLNGLTSDQFLDALTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) TGKEQPDESVVDGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LETVEEAGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.1%) GO:0006401 (0.1%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.1%) RNA catabolic process (0.1%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR003029 (8%) IPR012162 (8%) IPR004087 (7.9%)" "S1 domain (8%) Polyribonucleotide nucleotidyltransferase (8%) K Homology domain (7.9%)" PFVETHFDYETFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLLSNVLK root "2.7.7.6 (66.7%) 1.1.1.23 (7.4%) 1.1.1.211 (3.7%)" "DNA-directed RNA polymerase (66.7%) histidinol dehydrogenase (7.4%) long-chain-3-hydroxyacyl-CoA dehydrogenase (3.7%)" "GO:0006351 (5.5%) GO:0006884 (1.7%) GO:0007268 (1.7%)" "GO:0000428 (5.5%) GO:0005886 (5.2%) GO:0016020 (3.8%)" "GO:0003677 (5.9%) GO:0003899 (5.9%) GO:0008270 (5.9%)" "DNA-templated transcription (5.5%) cell volume homeostasis (1.7%) chemical synaptic transmission (1.7%)" "DNA-directed RNA polymerase complex (5.5%) plasma membrane (5.2%) membrane (3.8%)" "DNA binding (5.9%) DNA-directed RNA polymerase activity (5.9%) zinc ion binding (5.9%)" "IPR007081 (4.2%) IPR007083 (4.2%) IPR000722 (4%)" "RNA polymerase Rpb1, domain 5 (4.2%) RNA polymerase Rpb1, domain 4 (4.2%) RNA polymerase, alpha subunit (4%)" KLDCAVVQTALTYNQDANAHPYDSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GSAYMYTTNSHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (22.2%) IPR057601 (22.2%) IPR008969 (19.4%)" "TonB-dependent receptor-like (22.2%) TonB-dependent transporter Oar-like, beta-barrel domain (22.2%) Carboxypeptidase-like, regulatory domain superfamily (19.4%)" VNKGETSFATLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (27.4%) IPR050280 (25.8%) IPR046357 (24.2%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (27.4%) Outer Membrane Protein Chaperone SurA (25.8%) Peptidyl-prolyl cis-trans isomerase domain superfamily (24.2%)" DYYVNDDEQTKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" LLVYTQGR root "3.4.21.102 (54.2%) 3.4.21.- (45.8%)" "C-terminal processing peptidase (54.2%) Serine endopeptidases (45.8%)" "GO:0006508 (18.1%) GO:0007165 (18.1%) GO:0006623 (0.2%)" "GO:0030288 (18.1%) GO:0016020 (10%) GO:0005737 (0.2%)" "GO:0004175 (16.1%) GO:0008236 (16.1%) GO:0004252 (2%)" "proteolysis (18.1%) signal transduction (18.1%) protein targeting to vacuole (0.2%)" "outer membrane-bounded periplasmic space (18.1%) membrane (10%) cytoplasm (0.2%)" "endopeptidase activity (16.1%) serine-type peptidase activity (16.1%) serine-type endopeptidase activity (2%)" "IPR005151 (18.6%) IPR004447 (18.5%) IPR001478 (18.4%)" "Tail specific protease (18.6%) C-terminal-processing peptidase S41A (18.5%) PDZ domain (18.4%)" AMDNALLR root "2.5.1.10 (28.6%) 2.5.1.- (14.3%) 2.5.1.1 (14.3%)" "(2E,6E)-farnesyl diphosphate synthase (28.6%) Transferring alkyl or aryl groups, other than methyl groups (14.3%) dimethylallyltranstransferase (14.3%)" "GO:0008299 (8.3%) GO:0016114 (4.2%) GO:0010556 (2.8%)" "GO:0009279 (8.3%) GO:0010008 (4.2%) GO:0005765 (2.8%)" "GO:0004659 (9.7%) GO:0005524 (8.3%) GO:0005319 (6.9%)" "isoprenoid biosynthetic process (8.3%) terpenoid biosynthetic process (4.2%) regulation of macromolecule biosynthetic process (2.8%)" "cell outer membrane (8.3%) endosome membrane (4.2%) lysosomal membrane (2.8%)" "prenyltransferase activity (9.7%) ATP binding (8.3%) lipid transporter activity (6.9%)" "IPR000092 (6.5%) IPR008949 (6.5%) IPR033749 (5.1%)" "Polyprenyl synthetase-like (6.5%) Isoprenoid synthase domain superfamily (6.5%) Polyprenyl synthetase, conserved site (5.1%)" CELFMGATDVER Pseudomonadati Bacteria Pseudomonadati 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (50%) GO:0004834 (50%) cytoplasm (50%) tryptophan synthase activity (50%) "IPR001926 (20.2%) IPR006653 (20.2%) IPR023026 (20.2%)" "Tryptophan synthase beta chain-like, PALP domain (20.2%) Tryptophan synthase, beta chain, conserved site (20.2%) Tryptophan synthase beta chain/beta chain-like (20.2%)" SLHAVNVAATEVCHYFNPDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.8%) IPR022147 (14.8%) IPR052725 (14.8%)" "Glutamine synthetase, N-terminal domain (14.8%) Glutamine synthetase type III N-terminal (14.8%) Glutamine Synthetase Type-3 (14.8%)" YAPGDPAGNMNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR019734 (26%) IPR025738 (26%) IPR011990 (24.7%)" "Tetratricopeptide repeat (26%) Aerotolerance-related protein BatD (26%) Tetratricopeptide-like helical domain superfamily (24.7%)" GHAFSLGAGYELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) YLLKPAPWDNTLYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005829 (50%) GO:0004674 (50%) cytosol (50%) protein serine/threonine kinase activity (50%) "IPR012893 (50%) IPR052028 (50%)" "HipA-like, C-terminal (50%) HipA Serine/Threonine-Protein Kinase (50%)" LTALQSSFSVNCLALVNGRPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (13%) IPR050220 (13%) IPR005743 (12.7%)" "DNA topoisomerase, type IIA, domain A (13%) Type II DNA Topoisomerases (13%) DNA gyrase, subunit A (12.7%)" AYTGENQTEVLAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (100%) cell division (100%) "IPR019734 (35.6%) IPR011990 (34.5%) IPR051685 (29.9%)" "Tetratricopeptide repeat (35.6%) Tetratricopeptide-like helical domain superfamily (34.5%) Ycf3/AcsC/BcsC/TPR Multifunctional (29.9%)" QALTNLGLDTSGLGTADTDWQDELFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" VGDLALLYAELLNETAGPSTEALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VGTGFTLEQEALQYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.14 (100%) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (100%) "GO:0009086 (25%) GO:0032259 (25%)" "GO:0003871 (25%) GO:0008270 (25%)" "methionine biosynthetic process (25%) methylation (25%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (25%) zinc ion binding (25%)" "IPR002629 (51.6%) IPR038071 (48.4%)" "Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (51.6%) UROD/MetE-like superfamily (48.4%)" FYTDQFGYYSHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (12.9%) IPR002772 (12.9%) IPR026891 (12.9%)" "Glycoside hydrolase, family 3, N-terminal (12.9%) Glycoside hydrolase family 3 C-terminal domain (12.9%) Fibronectin type III-like domain (12.9%)" VLVPDADEQERNPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.1.1.199 (91.7%) 2.1.1.- (8.3%)" "16S rRNA (cytosine(1402)-N(4))-methyltransferase (91.7%) Methyltransferases (8.3%)" "GO:0070475 (31.4%) GO:0032259 (2.9%)" GO:0005737 (31.4%) "GO:0071424 (31.4%) GO:0008168 (2.9%)" "rRNA base methylation (31.4%) methylation (2.9%)" cytoplasm (31.4%) "rRNA (cytosine-N4-)-methyltransferase activity (31.4%) methyltransferase activity (2.9%)" "IPR002903 (34.3%) IPR029063 (34.3%) IPR023397 (31.4%)" "Ribosomal RNA small subunit methyltransferase H (34.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (34.3%) S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily (31.4%)" AMEMQNTDLTNYLEDHVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (80%) GO:0016740 (20%)" "glycosyltransferase activity (80%) transferase activity (20%)" "IPR000836 (25.7%) IPR017932 (25.7%) IPR029055 (24.3%)" "Phosphoribosyltransferase domain (25.7%) Glutamine amidotransferase type 2 domain (25.7%) Nucleophile aminohydrolases, N-terminal (24.3%)" WVNYALK root "2.6.1.83 (87%) 5.4.99.12 (13%)" "LL-diaminopimelate aminotransferase (87%) tRNA pseudouridine(38-40) synthase (13%)" "GO:0033362 (20.8%) GO:0031119 (4.2%) GO:1990481 (4.2%)" "GO:0005634 (4.2%) GO:0005737 (4.2%) GO:0016020 (2.6%)" "GO:0030170 (22.9%) GO:0010285 (20.8%) GO:0003723 (4.2%)" "lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (20.8%) tRNA pseudouridine synthesis (4.2%) mRNA pseudouridine synthesis (4.2%)" "nucleus (4.2%) cytoplasm (4.2%) membrane (2.6%)" "pyridoxal phosphate binding (22.9%) L,L-diaminopimelate aminotransferase activity (20.8%) RNA binding (4.2%)" "IPR004839 (16.9%) IPR019942 (16.9%) IPR015421 (16.1%)" "Aminotransferase, class I/classII, large domain (16.9%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (16.9%) Pyridoxal phosphate-dependent transferase, major domain (16.1%)" MVADLDMSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) GGATEEEAKDLFDAVLENR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.18 (100%) anthranilate phosphoribosyltransferase (100%) GO:0000162 (25%) GO:0005829 (25%) "GO:0000287 (25%) GO:0004048 (25%)" L-tryptophan biosynthetic process (25%) cytosol (25%) "magnesium ion binding (25%) anthranilate phosphoribosyltransferase activity (25%)" "IPR000312 (20.5%) IPR005940 (20.5%) IPR017459 (20.5%)" "Glycosyl transferase, family 3 (20.5%) Anthranilate phosphoribosyl transferase (20.5%) Glycosyl transferase family 3, N-terminal domain (20.5%)" RHDFFTENGCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (50%) IPR032466 (50%)" "Uronate isomerase (50%) Metal-dependent hydrolase (50%)" WDYVSAFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.80 (66.7%) 3.2.1.65 (33.3%)" "fructan beta-fructosidase (66.7%) levanase (33.3%)" GO:0005987 (32.1%) GO:0005737 (32.1%) "GO:0004575 (32.1%) GO:0051669 (2.6%) GO:0031219 (1.3%)" sucrose catabolic process (32.1%) cytoplasm (32.1%) "sucrose alpha-glucosidase activity (32.1%) fructan beta-fructosidase activity (2.6%) levanase activity (1.3%)" "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" WSTYFMK root "3.5.1.108 (50.4%) 4.2.1.59 (48.7%) 4.2.1.- (0.9%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50.4%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (48.7%) Hydro-lyases (0.9%)" "GO:0009245 (14.2%) GO:0006633 (13.7%)" "GO:0005737 (14.2%) GO:0016020 (14.2%) GO:0005886 (0.2%)" "GO:0046872 (14.2%) GO:0103117 (14.2%) GO:0016836 (7.7%)" "lipid A biosynthetic process (14.2%) fatty acid biosynthetic process (13.7%)" "cytoplasm (14.2%) membrane (14.2%) plasma membrane (0.2%)" "metal ion binding (14.2%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.2%) hydro-lyase activity (7.7%)" "IPR013114 (14.5%) IPR004463 (14.3%) IPR029069 (14%)" "Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.5%) UDP-3-O-acyl N-acetylglucosamine deacetylase (14.3%) HotDog domain superfamily (14%)" VAADANVLTVMVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KVLNLPSWDFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (9.5%) IPR006103 (9.5%) IPR006104 (9.5%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.5%) Glycoside hydrolase family 2, catalytic domain (9.5%) Glycosyl hydrolases family 2, sugar binding domain (9.5%)" VVLVPVNVLTTTQGYTTVLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) GYTDDDPSTNSFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DTYELLR root "2.3.3.13 (9.8%) 3.1.21.- (9.8%) 4.2.1.28 (7.3%)" "2-isopropylmalate synthase (9.8%) Endodeoxyribonucleases producing 5'-phosphomonoesters (9.8%) propanediol dehydratase (7.3%)" "GO:0006139 (1.6%) GO:0006406 (1.2%) GO:0006606 (1.2%)" "GO:0005829 (6.4%) GO:0016020 (3.4%) GO:0005737 (2.2%)" "GO:0046872 (9.7%) GO:0004536 (5.6%) GO:0016788 (4.8%)" "nucleobase-containing compound metabolic process (1.6%) mRNA export from nucleus (1.2%) protein import into nucleus (1.2%)" "cytosol (6.4%) membrane (3.4%) cytoplasm (2.2%)" "metal ion binding (9.7%) DNA nuclease activity (5.6%) hydrolase activity, acting on ester bonds (4.8%)" "IPR001130 (4%) IPR015991 (4%) IPR032466 (4%)" "3'-5' ssDNA/RNA exonuclease TatD-like (4%) Hydrolase TatD/YcfH-like (4%) Metal-dependent hydrolase (4%)" AECVLLNGVECEPYLTADYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.-.-.- (100%) Translocases (100%) GO:0022900 (19.5%) "GO:0005886 (19.5%) GO:0016020 (0.6%)" "GO:0009055 (20.1%) GO:0046872 (20.1%) GO:0051539 (20.1%)" electron transport chain (19.5%) "plasma membrane (19.5%) membrane (0.6%)" "electron transfer activity (20.1%) metal ion binding (20.1%) 4 iron, 4 sulfur cluster binding (20.1%)" "IPR010208 (14.7%) IPR011538 (14.7%) IPR017896 (14.2%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.7%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.7%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.2%)" FTWYLDK root 2.7.13.3 (100%) histidine kinase (100%) "GO:0006355 (9.1%) GO:0030435 (9.1%) GO:0006099 (3%)" "GO:0016020 (15.2%) GO:0005743 (3%) GO:0005794 (3%)" "GO:0005524 (12.1%) GO:0000155 (9.1%) GO:0003678 (3%)" "regulation of DNA-templated transcription (9.1%) sporulation resulting in formation of a cellular spore (9.1%) tricarboxylic acid cycle (3%)" "membrane (15.2%) mitochondrial inner membrane (3%) Golgi apparatus (3%)" "ATP binding (12.1%) phosphorelay sensor kinase activity (9.1%) DNA helicase activity (3%)" "IPR000014 (5.2%) IPR003594 (5.2%) IPR003661 (5.2%)" "PAS domain (5.2%) Histidine kinase/HSP90-like ATPase domain (5.2%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (5.2%)" MKDPETGNYVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) CCVSGAGSLNVDYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (97.5%) 2.7.-.- (2.5%)" "pyruvate, phosphate dikinase (97.5%) Transferring phosphorus-containing groups (2.5%)" "GO:0050242 (25.5%) GO:0005524 (24.8%) GO:0016301 (24.8%)" "pyruvate, phosphate dikinase activity (25.5%) ATP binding (24.8%) kinase activity (24.8%)" "IPR000121 (10.2%) IPR010121 (10.2%) IPR015813 (10.2%)" "PEP-utilising enzyme, C-terminal (10.2%) Pyruvate, phosphate dikinase (10.2%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.2%)" GLQLTAASGLEDATLVMNSESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TLYYSHGFALNWSDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.86 (90.5%) 1.1.1.- (9.5%)" "ketol-acid reductoisomerase (NADP(+)) (90.5%) With NAD(+) or NADP(+) as acceptor (9.5%)" "GO:0009097 (21.3%) GO:0009099 (21.3%)" "GO:0004455 (21.3%) GO:0046872 (20.2%) GO:0016853 (15.7%)" "isoleucine biosynthetic process (21.3%) L-valine biosynthetic process (21.3%)" "ketol-acid reductoisomerase activity (21.3%) metal ion binding (20.2%) isomerase activity (15.7%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" FKGYAFQLEMK Bacteria Bacteria "2.4.-.- (28%) 2.4.1.83 (20.7%) 2.4.1.- (19.5%)" "Glycosyltransferases (28%) dolichyl-phosphate beta-D-mannosyltransferase (20.7%) Hexosyltransferases (19.5%)" GO:0009247 (32.4%) GO:0016020 (32.4%) "GO:0004582 (32.4%) GO:0099621 (1.5%) GO:0047267 (0.7%)" glycolipid biosynthetic process (32.4%) membrane (32.4%) "dolichyl-phosphate beta-D-mannosyltransferase activity (32.4%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (1.5%) undecaprenyl-phosphate mannosyltransferase activity (0.7%)" "IPR039528 (33.4%) IPR029044 (33.3%) IPR001173 (33.2%)" "DPM1-like (33.4%) Nucleotide-diphospho-sugar transferases (33.3%) Glycosyltransferase 2-like (33.2%)" MMELSNLLPVLASANQQAAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) MQNRPLALLVDALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.19 (100%) 3-phosphoshikimate 1-carboxyvinyltransferase (100%) "GO:0009423 (25.8%) GO:0009073 (24.7%) GO:0008652 (23.6%)" GO:0003866 (25.8%) "chorismate biosynthetic process (25.8%) aromatic amino acid family biosynthetic process (24.7%) amino acid biosynthetic process (23.6%)" 3-phosphoshikimate 1-carboxyvinyltransferase activity (25.8%) "IPR001986 (20.7%) IPR006264 (19.8%) IPR013792 (19.8%)" "Enolpyruvate transferase domain (20.7%) 3-phosphoshikimate 1-carboxyvinyltransferase (19.8%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (19.8%)" LSTPVLLENPEVSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (20%) GO:0009099 (20%)" GO:0005829 (20%) "GO:0003984 (20%) GO:1990610 (20%)" "isoleucine biosynthetic process (20%) L-valine biosynthetic process (20%)" cytosol (20%) "acetolactate synthase activity (20%) acetolactate synthase regulator activity (20%)" "IPR019455 (15.4%) IPR027271 (15.4%) IPR045865 (15.4%)" "Acetolactate synthase, small subunit, C-terminal (15.4%) Acetolactate synthase/Transcription factor NikR, C-terminal (15.4%) ACT-like domain (15.4%)" STGVSYLR root 1.13.11.11 (100%) tryptophan 2,3-dioxygenase (100%) "GO:0007015 (4%) GO:0006811 (2%) GO:0019441 (2%)" "GO:0009279 (44%) GO:0016020 (6%) GO:0005737 (4%)" "GO:0000146 (4%) GO:0005524 (4%) GO:0051015 (4%)" "actin filament organization (4%) monoatomic ion transport (2%) L-tryptophan catabolic process to kynurenine (2%)" "cell outer membrane (44%) membrane (6%) cytoplasm (4%)" "microfilament motor activity (4%) ATP binding (4%) actin filament binding (4%)" "IPR012944 (22.8%) IPR033985 (22.8%) IPR011990 (20.7%)" "RagB/SusD domain (22.8%) SusD-like, N-terminal (22.8%) Tetratricopeptide-like helical domain superfamily (20.7%)" ELEYYDDEELDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) WGWFPSVAAAWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" YGWSFAEAQQLEQVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR001375 (33.9%) IPR052920 (33.9%) IPR029058 (32.1%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (33.9%) Potential DNA-binding regulatory protein (33.9%) Alpha/Beta hydrolase fold (32.1%)" VSLKDVATPYNSWQPYQAYLLDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (52.9%) IPR050811 (47.1%)" "PBP domain (52.9%) Phosphate-binding ABC transporter substrate-binding (47.1%)" ASHVYYLDFQLPFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006355 (50%) GO:0003677 (50%) regulation of DNA-templated transcription (50%) DNA binding (50%) "IPR000792 (25%) IPR012312 (25%) IPR016032 (25%)" "Transcription regulator LuxR, C-terminal (25%) Hemerythrin-like (25%) Signal transduction response regulator, C-terminal effector (25%)" ALFPWQNAWYPADRR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.4%) GO:0006164 (0.9%)" GO:0005737 (20.4%) "GO:0004642 (20.4%) GO:0005524 (19.4%) GO:0046872 (19.4%)" "'de novo' IMP biosynthetic process (19.4%) purine nucleotide biosynthetic process (0.9%)" cytoplasm (20.4%) "phosphoribosylformylglycinamidine synthase activity (20.4%) ATP binding (19.4%) metal ion binding (19.4%)" "IPR010918 (11.3%) IPR029062 (11.3%) IPR055181 (11.3%)" "PurM-like, C-terminal domain (11.3%) Class I glutamine amidotransferase-like (11.3%) FGAR-AT, PurM N-terminal-like domain (11.3%)" VCGVVMHLVCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) IPR017039 (100%) Virulence factor BrkB (100%) AAYAEESFYVGADKLAELSALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005840 (52.6%) GO:1990904 (47.4%)" "ribosome (52.6%) ribonucleoprotein complex (47.4%)" "IPR001790 (34.5%) IPR047865 (34.5%) IPR043141 (31%)" "Large ribosomal subunit protein uL10 (34.5%) Large ribosomal subunit protein uL10, bacteria/organella (34.5%) Large ribosomal subunit protein uL10-like domain superfamily (31%)" KVVVDNLPFLLADTVGFLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005737 (20.2%) "GO:0005525 (20.2%) GO:0043022 (20.2%) GO:0003924 (19.6%)" cytoplasm (20.2%) "GTP binding (20.2%) ribosome binding (20.2%) GTPase activity (19.6%)" "IPR006073 (13.3%) IPR016496 (13.3%) IPR030394 (13.3%)" "GTP binding domain (13.3%) GTPase HflX (13.3%) HflX-type guanine nucleotide-binding (G) domain (13.3%)" DENYKVEEYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015990 (20.2%) GO:0042773 (20.2%)" "GO:0016020 (20.2%) GO:0012505 (19.3%)" GO:0008137 (20.2%) "electron transport coupled proton transport (20.2%) ATP synthesis coupled electron transport (20.2%)" "membrane (20.2%) endomembrane system (19.3%)" NADH dehydrogenase (ubiquinone) activity (20.2%) "IPR001750 (25.6%) IPR003945 (25.6%) IPR001516 (24.4%)" "NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain (25.6%) NADH-quinone oxidoreductase, chain 5-like (25.6%) NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal (24.4%)" EQPDESVVDGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LPADLDWTSYLNSLADVQKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025396 (100%) Protein of unknown function DUF4302 (100%) AEDVPSLVEGFYGAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000272 (31.3%) GO:0005576 (31.3%) "GO:0030570 (31.3%) GO:0004557 (6.3%)" polysaccharide catabolic process (31.3%) extracellular region (31.3%) "pectate lyase activity (31.3%) alpha-galactosidase activity (6.3%)" "IPR002022 (18.3%) IPR011050 (18.3%) IPR012334 (18.3%)" "Pectate lyase (18.3%) Pectin lyase fold/virulence factor (18.3%) Pectin lyase fold (18.3%)" FNLDNFK root "1.14.14.14 (42.1%) 3.1.12.1 (15.8%) 2.3.1.275 (10.5%)" "aromatase (42.1%) 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming) (15.8%) acyl phosphate:glycerol-3-phosphate acyltransferase (10.5%)" "GO:0009244 (5.1%) GO:0055085 (2.8%) GO:0000462 (2.1%)" "GO:0005829 (5.1%) GO:0016020 (5.1%) GO:0005886 (4.7%)" "GO:0008713 (5.1%) GO:0003723 (3.3%) GO:0005506 (1.9%)" "lipopolysaccharide core region biosynthetic process (5.1%) transmembrane transport (2.8%) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (2.1%)" "cytosol (5.1%) membrane (5.1%) plasma membrane (4.7%)" "ADP-heptose-lipopolysaccharide heptosyltransferase activity (5.1%) RNA binding (3.3%) iron ion binding (1.9%)" "IPR051199 (3.9%) IPR002201 (3.7%) IPR000515 (2.5%)" "Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase (3.9%) Glycosyl transferase, family 9 (3.7%) ABC transporter type 1, transmembrane domain MetI-like (2.5%)" QLCLDRDPHGNVQVSLLETEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.7%) GO:0006002 (13.2%)" GO:0005829 (14.7%) "GO:0003872 (14.7%) GO:0005524 (14.2%) GO:0046872 (14.2%)" "response to glucose (14.7%) fructose 6-phosphate metabolic process (13.2%)" cytosol (14.7%) "6-phosphofructokinase activity (14.7%) ATP binding (14.2%) metal ion binding (14.2%)" "IPR000023 (25.7%) IPR011183 (25.7%) IPR035966 (24.8%)" "Phosphofructokinase domain (25.7%) Pyrophosphate-dependent phosphofructokinase PfpB (25.7%) Phosphofructokinase superfamily (24.8%)" FPDMHEAYDKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.1 (100%) purine-nucleoside phosphorylase (100%) GO:0009116 (33.3%) GO:0005737 (33.3%) GO:0004731 (33.3%) nucleoside metabolic process (33.3%) cytoplasm (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (26.3%) IPR011268 (26.3%) IPR011270 (23.7%)" "Nucleoside phosphorylase domain (26.3%) Purine nucleoside phosphorylase (26.3%) Purine nucleoside phosphorylase I, inosine/guanosine-specific (23.7%)" NGNPLSPQFSDVVLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.1%) IPR008969 (11.1%) IPR012910 (11.1%)" "TonB-dependent receptor-like, beta-barrel (11.1%) Carboxypeptidase-like, regulatory domain superfamily (11.1%) TonB-dependent receptor, plug domain (11.1%)" WGGNSTWAGTVNPVAQSQDAGYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" MFSDELK root "3.4.21.89 (65.6%) 6.2.1.30 (28.1%) 3.5.99.2 (3.1%)" "signal peptidase I (65.6%) phenylacetate--CoA ligase (28.1%) aminopyrimidine aminohydrolase (3.1%)" "GO:0006352 (12.5%) GO:0009228 (4%) GO:0006465 (3.4%)" "GO:0005737 (12.4%) GO:0005787 (3.4%) GO:0016020 (1.8%)" "GO:0003677 (14.3%) GO:0016987 (12.5%) GO:0005506 (3.9%)" "DNA-templated transcription initiation (12.5%) thiamine biosynthetic process (4%) signal peptide processing (3.4%)" "cytoplasm (12.4%) signal peptidase complex (3.4%) membrane (1.8%)" "DNA binding (14.3%) sigma factor activity (12.5%) iron ion binding (3.9%)" "IPR007627 (5.8%) IPR013324 (5.8%) IPR013325 (5.8%)" "RNA polymerase sigma-70 region 2 (5.8%) RNA polymerase sigma factor, region 3/4-like (5.8%) RNA polymerase sigma factor, region 2 (5.8%)" HTELLHDVYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025381 (100%) Domain of unknown function DUF4296 (100%) LVFLNSVVGGALDSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.7%) IPR000795 (7.7%) IPR005225 (7.7%)" "Elongation factor EFG, domain V-like (7.7%) Translational (tr)-type GTP-binding domain (7.7%) Small GTP-binding domain (7.7%)" ESYQSSVQNEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" VRDVYDLNDDLLVMVATDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) GO:0005737 (25%) "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) cytoplasm (25%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR028923 (50.9%) IPR018236 (49.1%)" "SAICAR synthetase/ADE2, N-terminal (50.9%) SAICAR synthetase, conserved site (49.1%)" LPATGYKPLTFEVSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.7%) IPR025896 (16.7%) IPR026906 (16.7%)" "Peptidase C10, streptopain (16.7%) Spi protease inhibitor (16.7%) BspA-type LRR region (16.7%)" TMLDDWNHYVEDFLQVVPLEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.1%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.1%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" DLLVNFK root "5.4.99.- (14.3%) 2.4.1.142 (8.6%) 4.1.1.31 (8.6%)" "Transferring other groups (14.3%) chitobiosyldiphosphodolichol beta-mannosyltransferase (8.6%) phosphoenolpyruvate carboxylase (8.6%)" "GO:0006606 (4.2%) GO:0006099 (1.6%) GO:0015977 (1.6%)" "GO:0016020 (8.6%) GO:0005829 (6.6%) GO:0005783 (6%)" "GO:0005254 (6.5%) GO:0031267 (4.2%) GO:0016757 (2%)" "protein import into nucleus (4.2%) tricarboxylic acid cycle (1.6%) carbon fixation (1.6%)" "membrane (8.6%) cytosol (6.6%) endoplasmic reticulum (6%)" "chloride channel activity (6.5%) small GTPase binding (4.2%) glycosyltransferase activity (2%)" "IPR009231 (6.3%) IPR016024 (4.4%) IPR011989 (4.2%)" "Chloride channel CLIC-like (6.3%) Armadillo-type fold (4.4%) Armadillo-like helical (4.2%)" EAYYTNTYSGDGGLHQAYLGAGWEPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KVEALFADATDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.7%) IPR003385 (20.7%) IPR013783 (19.5%)" "Carbohydrate binding module family 20 (20.7%) Glycoside hydrolase, family 77 (20.7%) Immunoglobulin-like fold (19.5%)" WDLLANR root "5.6.2.2 (43.1%) 1.18.1.- (38.9%) 2.4.1.18 (4.2%)" "DNA topoisomerase (ATP-hydrolyzing) (43.1%) With NAD(+) or NADP(+) as acceptor (38.9%) 1,4-alpha-glucan branching enzyme (4.2%)" "GO:0006265 (4.2%) GO:0016226 (4.1%) GO:0006261 (3.5%)" "GO:0005829 (6%) GO:0005634 (4.1%) GO:0048471 (3.8%)" "GO:0005524 (4.9%) GO:0046872 (4.9%) GO:0010181 (4.4%)" "DNA topological change (4.2%) iron-sulfur cluster assembly (4.1%) DNA-templated DNA replication (3.5%)" "cytosol (6%) nucleus (4.1%) perinuclear region of cytoplasm (3.8%)" "ATP binding (4.9%) metal ion binding (4.9%) FMN binding (4.4%)" "IPR039261 (3.3%) IPR001433 (3.2%) IPR001709 (3.1%)" "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain (3.3%) Oxidoreductase FAD/NAD(P)-binding (3.2%) Flavoprotein pyridine nucleotide cytochrome reductase (3.1%)" NHEELYFFLSGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR013096 (25.8%) IPR051610 (25.8%) IPR011051 (24.2%)" "Cupin 2, conserved barrel (25.8%) Glucose-6-phosphate isomerase/Oxalate decarboxylase (25.8%) RmlC-like cupin domain superfamily (24.2%)" VSLSADDEQCQDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006139 (20%) GO:0006412 (20%)" GO:0005737 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "nucleobase-containing compound metabolic process (20%) translation (20%)" cytoplasm (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR003029 (7.3%) IPR006641 (7.3%) IPR018974 (7.3%)" "S1 domain (7.3%) YqgF/RNase H-like domain (7.3%) Tex-like protein, N-terminal (7.3%)" LLELVWEGWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.5%) IPR011990 (32.7%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.5%) Tetratricopeptide-like helical domain superfamily (32.7%)" KALANLQEQLAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AAGLDLKDVLSELVENQF Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.3%) GO:0008360 (13.3%) GO:0009252 (13.3%)" GO:0005737 (13.3%) "GO:0005524 (15.3%) GO:0008716 (15.3%) GO:0046872 (15.3%)" "cell wall organization (14.3%) regulation of cell shape (13.3%) peptidoglycan biosynthetic process (13.3%)" cytoplasm (13.3%) "ATP binding (15.3%) D-alanine-D-alanine ligase activity (15.3%) metal ion binding (15.3%)" "IPR011095 (15.3%) IPR011761 (15.3%) IPR000291 (14.3%)" "D-alanine--D-alanine ligase, C-terminal (15.3%) ATP-grasp fold (15.3%) D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.3%)" FSLLQGTALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR000421 (16.7%) IPR006710 (16.7%) IPR008979 (16.7%)" "Coagulation factor 5/8, C-terminal domain (16.7%) Glycoside hydrolase, family 43 (16.7%) Galactose-binding-like domain superfamily (16.7%)" YDFYSLVHVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003677 (50%) GO:0003700 (50%)" "DNA binding (50%) DNA-binding transcription factor activity (50%)" "IPR000524 (20%) IPR008920 (20%) IPR011711 (20%)" "Transcription regulator HTH, GntR (20%) Transcription regulator FadR/GntR, C-terminal (20%) GntR, C-terminal (20%)" VFAFYGK root "GO:0002949 (21.8%) GO:0007214 (0.2%) GO:0006081 (0.1%)" "GO:0005737 (22%) GO:0005886 (0.2%) GO:0038039 (0.2%)" "GO:0005524 (22%) GO:0046872 (21.8%) GO:0016740 (6.1%)" "tRNA threonylcarbamoyladenosine modification (21.8%) gamma-aminobutyric acid signaling pathway (0.2%) aldehyde metabolic process (0.1%)" "cytoplasm (22%) plasma membrane (0.2%) G protein-coupled receptor heterodimeric complex (0.2%)" "ATP binding (22%) metal ion binding (21.8%) transferase activity (6.1%)" "IPR027417 (46.1%) IPR003442 (45.8%) IPR000337 (0.5%)" "P-loop containing nucleoside triphosphate hydrolase (46.1%) tRNA threonylcarbamoyl adenosine modification protein TsaE (45.8%) GPCR, family 3 (0.5%)" VFWFVVANAGNPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (25%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR001789 (10.9%) IPR009057 (10.9%) IPR011006 (10.9%)" "Signal transduction response regulator, receiver domain (10.9%) Homedomain-like superfamily (10.9%) CheY-like superfamily (10.9%)" QLPMLGLCR Bacteria Bacteria "3.4.13.- (85.7%) 2.4.2.- (4.8%) 2.6.-.- (4.8%)" "Dipeptidases (85.7%) Pentosyltransferases (4.8%) Transferring nitrogenous groups (4.8%)" "GO:0006508 (46.2%) GO:0006598 (0.5%)" GO:0005829 (1.6%) "GO:0070573 (46.2%) GO:0016740 (3.3%) GO:0016811 (1.1%)" "proteolysis (46.2%) polyamine catabolic process (0.5%)" cytosol (1.6%) "metallodipeptidase activity (46.2%) transferase activity (3.3%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (1.1%)" "IPR011697 (25.2%) IPR029062 (24.9%) IPR008257 (24.4%)" "Peptidase C26 (25.2%) Class I glutamine amidotransferase-like (24.9%) Peptidase M19 (24.4%)" SNDEYELEECNNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000162 (51.7%) GO:0046872 (48.3%) L-tryptophan biosynthetic process (51.7%) metal ion binding (48.3%) "IPR006805 (25.4%) IPR015890 (25.4%) IPR019999 (25.4%)" "Anthranilate synthase component I, N-terminal (25.4%) Chorismate-utilising enzyme, C-terminal (25.4%) Anthranilate synthase component I-like (25.4%)" KAGLNPAHVDSEDHLESNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (50%) GO:0003746 (50%) cytoplasm (50%) translation elongation factor activity (50%) "IPR001816 (20.5%) IPR014039 (20.5%) IPR018101 (20.5%)" "Translation elongation factor EFTs/EF1B (20.5%) Translation elongation factor EFTs/EF1B, dimerisation (20.5%) Translation elongation factor Ts, conserved site (20.5%)" ADGNPNTFAFLGSPELTVALTLAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.6%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.6%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" PAGAPLAPGANPSYGAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" AGMLFAQTEGLLPAPESCHALAATLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (23.3%) IPR006316 (23.3%) IPR023026 (23.3%)" "Tryptophan synthase beta chain-like, PALP domain (23.3%) Tryptophan synthase, beta chain-like (23.3%) Tryptophan synthase beta chain/beta chain-like (23.3%)" DQMVGQQAEQMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (16.8%) IPR028053 (16.8%) IPR028055 (16.8%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (16.8%) Membrane insertase YidC, N-terminal (16.8%) Membrane insertase YidC/Oxa/ALB, C-terminal (16.8%)" QATELLAEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.7%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.7%)" "IPR000185 (7.9%) IPR011115 (7.9%) IPR014001 (7.9%)" "Protein translocase subunit SecA (7.9%) SecA DEAD-like, N-terminal (7.9%) Helicase superfamily 1/2, ATP-binding domain (7.9%)" LSPDWHDGSLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0042910 (50%) plasma membrane (50%) xenobiotic transmembrane transporter activity (50%) "IPR001036 (53.8%) IPR027463 (46.2%)" "Acriflavin resistance protein (53.8%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (46.2%)" NCNEMGQLPNAGFENFHEATYDSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" EHNMTLVQTSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.5 (100%) chorismate mutase (100%) "GO:0046417 (46.7%) GO:0009697 (6.7%)" GO:0004106 (46.7%) "chorismate metabolic process (46.7%) salicylic acid biosynthetic process (6.7%)" chorismate mutase activity (46.7%) "IPR002701 (20.6%) IPR006218 (17.6%) IPR052899 (17.6%)" "Chorismate mutase II, prokaryotic-type (20.6%) DAHP synthetase I/KDSA (17.6%) Class-I DAHP synthase (17.6%)" DHATNFYFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR041246 (20.7%) IPR001599 (18.6%) IPR002890 (18.6%)" "Bacterial alpha-2-macroglobulin MG10 domain (20.7%) Alpha-2-macroglobulin (18.6%) Macroglobulin domain (18.6%)" SLAELLPEFLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR007922 (100%) DciA-like (100%) KGDNLDYVVNSSSSLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.2 (100%) acid phosphatase (100%) "GO:0003993 (48.8%) GO:0046872 (48.8%) GO:0016787 (2.4%)" "acid phosphatase activity (48.8%) metal ion binding (48.8%) hydrolase activity (2.4%)" "IPR004843 (25.6%) IPR051558 (25.6%) IPR024927 (24.4%)" "Calcineurin-like, phosphoesterase domain (25.6%) Metallophosphoesterase Purple Acid Phosphatase (25.6%) Purple acid phosphatase (24.4%)" YDKNYLLTSLSFAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" EVVFSSGSLPLAMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR002641 (26.2%) IPR050301 (26.2%) IPR016035 (25.4%)" "Patatin-like phospholipase domain (26.2%) Neuropathy target esterase (26.2%) Acyl transferase/acyl hydrolase/lysophospholipase (25.4%)" AFDVLVEK root 1.2.7.4 (100%) anaerobic carbon-monoxide dehydrogenase (100%) "GO:0006310 (21.5%) GO:0015074 (21%) GO:0007165 (3.9%)" "GO:0000785 (0.9%) GO:0005634 (0.9%) GO:0005829 (0.9%)" "GO:0003677 (24.9%) GO:0043531 (3.4%) GO:0031177 (0.9%)" "DNA recombination (21.5%) DNA integration (21%) signal transduction (3.9%)" "chromatin (0.9%) nucleus (0.9%) cytosol (0.9%)" "DNA binding (24.9%) ADP binding (3.4%) phosphopantetheine binding (0.9%)" "IPR035386 (11.5%) IPR025269 (11.1%) IPR010998 (10.7%)" "Arm, DNA-binding domain (11.5%) Phage integrase SAM-like domain (11.1%) Integrase/recombinase, N-terminal (10.7%)" HDTWTSGLNVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GSDNWFVGGVTGMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" NNLPVGEEYLADLEKYEAEVLANR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (36.4%) IPR050337 (36.4%) IPR036237 (27.3%)" "Rhamnose isomerase (36.4%) L-rhamnose isomerase (36.4%) Xylose isomerase-like superfamily (27.3%)" NLVDSELLMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.8.4.4 (100%) [ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase (100%) "GO:0006400 (14.5%) GO:0032259 (1.6%)" "GO:0005829 (14.5%) GO:0005840 (14%)" "GO:0035599 (14.5%) GO:0046872 (14.5%) GO:0051539 (14.5%)" "tRNA modification (14.5%) methylation (1.6%)" "cytosol (14.5%) ribosome (14%)" "aspartic acid methylthiotransferase activity (14.5%) metal ion binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR002792 (10.1%) IPR005839 (10.1%) IPR005840 (10.1%)" "TRAM domain (10.1%) Methylthiotransferase (10.1%) Ribosomal protein uS12 methylthiotransferase RimO (10.1%)" HFTYDANNPASLPFDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (25%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR001789 (11.1%) IPR009057 (11.1%) IPR011006 (11.1%)" "Signal transduction response regulator, receiver domain (11.1%) Homedomain-like superfamily (11.1%) CheY-like superfamily (11.1%)" DYGFDDKDFQDEEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR027417 (34.9%) IPR052934 (34.9%) IPR011704 (30.2%)" "P-loop containing nucleoside triphosphate hydrolase (34.9%) Methylated DNA Recognition and Restriction Enzymes (34.9%) ATPase, dynein-related, AAA domain (30.2%)" QLGENTALAHLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.4 (100%) Transferred entry: 7.2.2.9 (100%) "GO:0055070 (14.3%) GO:0060003 (14.3%)" GO:0005886 (14.3%) "GO:0005507 (14.3%) GO:0005524 (14.3%) GO:0016887 (14.3%)" "copper ion homeostasis (14.3%) copper ion export (14.3%)" plasma membrane (14.3%) "copper ion binding (14.3%) ATP binding (14.3%) ATP hydrolysis activity (14.3%)" "IPR001757 (12.7%) IPR006121 (12.7%) IPR018303 (12.7%)" "P-type ATPase (12.7%) Heavy metal-associated domain, HMA (12.7%) P-type ATPase, phosphorylation site (12.7%)" ATFNLVDGTLSGEETPADLTMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (56.5%) IPR042278 (43.5%)" "Fimbrillin-like 1 (56.5%) Fimbrillin-like 1, N-terminal (43.5%)" LAEYEQTFLEAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (20.9%) IPR024361 (20.9%) IPR050386 (20.9%)" "Glycoside hydrolase, family 5 (20.9%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (20.9%) Glycosyl Hydrolase 5 (Cellulase A) (20.9%)" VTYGGVDALRPAEELDAEQFLAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006265 (16.6%) "GO:0005737 (16.6%) GO:0009330 (16.6%)" "GO:0003677 (16.6%) GO:0003918 (16.6%) GO:0005524 (16.6%)" DNA topological change (16.6%) "cytoplasm (16.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.6%)" "DNA binding (16.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.6%) ATP binding (16.6%)" "IPR002205 (20.7%) IPR050220 (20.7%) IPR013757 (19.6%)" "DNA topoisomerase, type IIA, domain A (20.7%) Type II DNA Topoisomerases (20.7%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.6%)" DKGDLSENSEYDAAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006354 (20.4%) GO:0032784 (20.4%)" "GO:0003677 (20.4%) GO:0070063 (20.4%) GO:0003746 (18.6%)" "DNA-templated transcription elongation (20.4%) regulation of DNA-templated transcription elongation (20.4%)" "DNA binding (20.4%) RNA polymerase binding (20.4%) translation elongation factor activity (18.6%)" "IPR001437 (14.1%) IPR006359 (14.1%) IPR022691 (14.1%)" "Transcription elongation factor, GreA/GreB, C-terminal (14.1%) Transcription elongation factor GreA (14.1%) Transcription elongation factor, GreA/GreB, N-terminal (14.1%)" LTAGVNYFWQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (28.6%) GO:0009279 (42.9%) GO:0015344 (28.6%) siderophore transmembrane transport (28.6%) cell outer membrane (42.9%) siderophore uptake transmembrane transporter activity (28.6%) "IPR000531 (44.4%) IPR036942 (33.3%) IPR039426 (22.2%)" "TonB-dependent receptor-like, beta-barrel (44.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (33.3%) TonB-dependent receptor-like (22.2%)" STLLVSDLVDFEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella KGGSQFHFLLGQEF Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0071709 (48.6%) "GO:0009279 (40.6%) GO:0019867 (10.9%)" membrane assembly (48.6%) "cell outer membrane (40.6%) outer membrane (10.9%)" "IPR010827 (24.4%) IPR034746 (24.4%) IPR023707 (23.9%)" "POTRA domain, BamA/TamA-like (24.4%) POTRA domain (24.4%) Outer membrane protein assembly factor BamA (23.9%)" SLLVSTLECYFQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR012547 (47.4%) IPR018631 (47.4%) IPR027417 (5.3%)" "PD-(D/E)XK nuclease superfamily 9 (47.4%) AAA-ATPase-like domain (47.4%) P-loop containing nucleoside triphosphate hydrolase (5.3%)" AVAGENGLYATACFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" LVFGCFSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0015990 (20%) GO:0042773 (20%)" "GO:0012505 (20%) GO:0016020 (20%)" GO:0008137 (20%) "electron transport coupled proton transport (20%) ATP synthesis coupled electron transport (20%)" "endomembrane system (20%) membrane (20%)" NADH dehydrogenase (ubiquinone) activity (20%) "IPR001516 (25%) IPR001750 (25%) IPR003945 (25%)" "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal (25%) NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain (25%) NADH-quinone oxidoreductase, chain 5-like (25%)" LGLFANVRPVATFDCLLHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) GO:0009098 (20%) GO:0005829 (20%) "GO:0000287 (20%) GO:0003862 (20%) GO:0051287 (20%)" L-leucine biosynthetic process (20%) cytosol (20%) "magnesium ion binding (20%) 3-isopropylmalate dehydrogenase activity (20%) NAD binding (20%)" "IPR004429 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isopropylmalate dehydrogenase (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" SYTNEHGESLQPNAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" NEFYPVPYNQLYYLPGLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.4%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.4%)" WSPVEGDEFAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.2.3 (100%) dihydroorotase (100%) GO:0006145 (24.3%) GO:0005737 (24.3%) "GO:0004038 (24.3%) GO:0046872 (22.6%) GO:0004151 (4.3%)" purine nucleobase catabolic process (24.3%) cytoplasm (24.3%) "allantoinase activity (24.3%) metal ion binding (22.6%) dihydroorotase activity (4.3%)" "IPR002195 (20.6%) IPR006680 (20.6%) IPR050138 (20.6%)" "Dihydroorotase, conserved site (20.6%) Amidohydrolase-related (20.6%) Dihydroorotase/Allantoinase Hydrolase (20.6%)" DLLFLSPTSYVTGFSSYWNNLGELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" LPLSLGGGLGQSR root 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (19.8%) GO:0006529 (4.8%)" GO:0005829 (24.5%) "GO:0004071 (24.5%) GO:0005524 (19.8%) GO:0000166 (4.8%)" "L-asparagine biosynthetic process (19.8%) obsolete asparagine biosynthetic process (4.8%)" cytosol (24.5%) "aspartate-ammonia ligase activity (24.5%) ATP binding (19.8%) nucleotide binding (4.8%)" "IPR004618 (33.4%) IPR006195 (33.4%) IPR045864 (33.2%)" "Aspartate--ammonia ligase (33.4%) Aminoacyl-tRNA synthetase, class II (33.4%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (33.2%)" LDSGSDTQVDVNLPSLSSGLVGDNVAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" QYLDLYQSSSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" SFYGESTGSVDCSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LGDGEQVAFTPGKAATFTLGADMMEGESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (53.8%) "GO:0016787 (38.5%) GO:0016829 (7.7%)" carbohydrate metabolic process (53.8%) "hydrolase activity (38.5%) lyase activity (7.7%)" "IPR013783 (26.7%) IPR031965 (26.7%) IPR006047 (23.3%)" "Immunoglobulin-like fold (26.7%) Starch-binding module 26 (26.7%) Glycosyl hydrolase family 13, catalytic domain (23.3%)" YYAQWAGAPYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016829 (100%) lyase activity (100%) "IPR003961 (26.1%) IPR033803 (26.1%) IPR013783 (23.9%)" "Fibronectin type III (26.1%) Golvesin/Xly, CBD-like (26.1%) Immunoglobulin-like fold (23.9%)" LLGSPAGYVGYEDGGLLTDALR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0034605 (21.6%) GO:0006508 (6.4%) GO:0043335 (0.6%)" GO:0005737 (21.6%) "GO:0005524 (21.8%) GO:0016887 (21.6%) GO:0008233 (6.4%)" "cellular response to heat (21.6%) proteolysis (6.4%) protein unfolding (0.6%)" cytoplasm (21.6%) "ATP binding (21.8%) ATP hydrolysis activity (21.6%) peptidase activity (6.4%)" "IPR003593 (9.5%) IPR003959 (9.5%) IPR019489 (9.5%)" "AAA+ ATPase domain (9.5%) ATPase, AAA-type, core (9.5%) Clp ATPase, C-terminal (9.5%)" KGDATDALVDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.8%) GO:0043335 (15.8%) GO:0051083 (15.8%)" GO:0005737 (5%) "GO:0003755 (15.8%) GO:0043022 (15.8%) GO:0044183 (15.8%)" "protein transport (15.8%) protein unfolding (15.8%) 'de novo' cotranslational protein folding (15.8%)" cytoplasm (5%) "peptidyl-prolyl cis-trans isomerase activity (15.8%) ribosome binding (15.8%) protein folding chaperone (15.8%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR027304 (18.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor/SurA domain superfamily (18.4%)" EEKPQLALMGATVLGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (17.2%) IPR014729 (17.2%) IPR014730 (17.2%)" "Electron transfer flavoprotein alpha subunit/FixB (17.2%) Rossmann-like alpha/beta/alpha sandwich fold (17.2%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (17.2%)" FDYYTGELKVVNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR025964 (100%) GGGtGRT protein (100%) WSGGWHNTFSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" CYELPEGDRNSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.8%) IPR005743 (12.8%) IPR006691 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA gyrase, subunit A (12.8%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%)" LMLPGDYLAMK Pseudomonadati Bacteria Pseudomonadati "2.7.1.17 (82.7%) 2.7.1.- (17.3%)" "xylulokinase (82.7%) Phosphotransferases with an alcohol group as acceptor (17.3%)" "GO:0005975 (46.8%) GO:0006355 (0.2%)" "GO:0016301 (47.5%) GO:0004856 (5.1%) GO:0003677 (0.2%)" "carbohydrate metabolic process (46.8%) regulation of DNA-templated transcription (0.2%)" "kinase activity (47.5%) D-xylulokinase activity (5.1%) DNA binding (0.2%)" "IPR018484 (20.3%) IPR050406 (20.3%) IPR043129 (20.1%)" "Carbohydrate kinase FGGY, N-terminal (20.3%) FGGY Carbohydrate Kinase (20.3%) ATPase, nucleotide binding domain (20.1%)" DVVLVPSKAEYGVLLDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (33.3%) IPR011607 (33.3%) IPR036914 (33.3%)" "Bifunctional purine biosynthesis protein PurH-like (33.3%) Methylglyoxal synthase-like domain (33.3%) Methylglyoxal synthase-like domain superfamily (33.3%)" YSFCDFLKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) LVLLDGYAANPGDLDYHLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.2%) GO:0033711 (2.8%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.2%) 4-phosphoerythronate dehydrogenase activity (2.8%)" "IPR006139 (20.7%) IPR050418 (20.7%) IPR006140 (19.5%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (20.7%) D-isomer specific 2-hydroxyacid dehydrogenase, PdxB subfamily (20.7%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (19.5%)" LYTTDDNNPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VLGLANSSLDRLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SETTLPYK root "2.1.1.- (83.3%) 2.1.1.191 (16.7%)" "Methyltransferases (83.3%) 23S rRNA (cytosine(1962)-C(5))-methyltransferase (16.7%)" "GO:0032259 (19.7%) GO:0006364 (19%) GO:0006526 (0.2%)" "GO:0005737 (20.2%) GO:0005634 (0.5%)" "GO:0003723 (19.7%) GO:0008168 (19.7%) GO:0005525 (0.5%)" "methylation (19.7%) rRNA processing (19%) L-arginine biosynthetic process (0.2%)" "cytoplasm (20.2%) nucleus (0.5%)" "RNA binding (19.7%) methyltransferase activity (19.7%) GTP binding (0.5%)" "IPR002478 (16.6%) IPR019614 (16.6%) IPR041532 (16.6%)" "PUA domain (16.6%) S-adenosylmethionine-dependent methyltransferase (16.6%) RlmI-like, PUA domain (16.6%)" TFGAAFATYELNDRNNFTSADAYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" TQYEAGLNFHLGKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.6%) IPR023614 (48.4%)" "Phosphate-selective porin O/P (51.6%) Porin domain superfamily (48.4%)" VDLEFDLPSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0009409 (10.1%) GO:0000027 (9.7%) GO:0010467 (9.7%)" "GO:0005829 (10.1%) GO:1990904 (10.1%)" "GO:0003924 (10.1%) GO:0005525 (10.1%) GO:0000049 (9.7%)" "response to cold (10.1%) ribosomal large subunit assembly (9.7%) gene expression (9.7%)" "cytosol (10.1%) ribonucleoprotein complex (10.1%)" "GTPase activity (10.1%) GTP binding (10.1%) tRNA binding (9.7%)" "IPR000640 (6.6%) IPR000795 (6.6%) IPR004161 (6.6%)" "Elongation factor EFG, domain V-like (6.6%) Translational (tr)-type GTP-binding domain (6.6%) Translation elongation factor EFTu-like, domain 2 (6.6%)" VPLLLNHPAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0015079 (33.3%) GO:0015293 (33.3%)" plasma membrane (33.3%) "potassium ion transmembrane transporter activity (33.3%) symporter activity (33.3%)" "IPR003855 (25%) IPR023051 (25%) IPR053951 (25%)" "Potassium transporter (25%) Low affinity potassium transport system protein Kup (25%) K+ potassium transporter, integral membrane domain (25%)" ALLALYPYYQTAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR011990 (50%) IPR019734 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) Tetratricopeptide repeat (50%)" LQSHTTTWGATVGGPLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (22.2%) IPR057601 (22.2%) IPR008969 (19.4%)" "TonB-dependent receptor-like (22.2%) TonB-dependent transporter Oar-like, beta-barrel domain (22.2%) Carboxypeptidase-like, regulatory domain superfamily (19.4%)" PVGSMTQYDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (28.4%) GO:0008654 (28.4%)" GO:0016020 (14.7%) GO:0004512 (28.4%) "inositol biosynthetic process (28.4%) phospholipid biosynthetic process (28.4%)" membrane (14.7%) inositol-3-phosphate synthase activity (28.4%) "IPR002587 (33.6%) IPR013021 (33.2%) IPR036291 (33.2%)" "Myo-inositol-1-phosphate synthase (33.6%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.2%) NAD(P)-binding domain superfamily (33.2%)" PVSVSDYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.4%) IPR019826 (20.4%) IPR050309 (20.4%)" "Carboxylesterase, type B (20.4%) Carboxylesterase type B, active site (20.4%) Type-B Carboxylesterase/Lipase (20.4%)" LYWESLPEGYEGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (50%) GO:0008460 (50%) nucleotide-sugar metabolic process (50%) dTDP-glucose 4,6-dehydratase activity (50%) "IPR036291 (33.5%) IPR005888 (32.3%) IPR001509 (29.9%)" "NAD(P)-binding domain superfamily (33.5%) dTDP-glucose 4,6-dehydratase (32.3%) NAD-dependent epimerase/dehydratase (29.9%)" YPDYYGLDMAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (12.5%) GO:0006189 (7.5%) GO:0006164 (5%)" "GO:0016757 (40%) GO:0004044 (20%) GO:0046872 (12.5%)" "purine nucleobase biosynthetic process (12.5%) 'de novo' IMP biosynthetic process (7.5%) purine nucleotide biosynthetic process (5%)" "glycosyltransferase activity (40%) amidophosphoribosyltransferase activity (20%) metal ion binding (12.5%)" "IPR017932 (25.5%) IPR029057 (25.5%) IPR029055 (25%)" "Glutamine amidotransferase type 2 domain (25.5%) Phosphoribosyltransferase-like (25.5%) Nucleophile aminohydrolases, N-terminal (25%)" YDALYHDYLDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) LYVFGHFEYYDSSVHNTTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR023614 (100%) Porin domain superfamily (100%) FAYLEVPEEDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.6.4.13 (95.8%) 3.6.4.- (4.2%)" "RNA helicase (95.8%) Acting on ATP; involved in cellular and subcellular movement (4.2%)" GO:0005829 (10.2%) "GO:0003724 (22.5%) GO:0005524 (22.5%) GO:0016787 (22.5%)" cytosol (10.2%) "RNA helicase activity (22.5%) ATP binding (22.5%) hydrolase activity (22.5%)" "IPR000629 (10.1%) IPR001650 (10.1%) IPR005580 (10.1%)" "ATP-dependent RNA helicase DEAD-box, conserved site (10.1%) Helicase, C-terminal domain-like (10.1%) DEAD box helicase DbpA/CsdA, RNA-binding domain (10.1%)" ALRDEFDPHGGR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (10.1%) IPR006104 (10.1%) IPR008979 (10.1%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (10.1%) Glycosyl hydrolases family 2, sugar binding domain (10.1%) Galactose-binding-like domain superfamily (10.1%)" YTNFENLSAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DHAELQQSLNHALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006865 (33.3%) GO:0043190 (33.3%) GO:0022857 (33.3%) amino acid transport (33.3%) ATP-binding cassette (ABC) transporter complex (33.3%) transmembrane transporter activity (33.3%) "IPR000515 (16.8%) IPR001638 (16.8%) IPR010065 (16.8%)" "ABC transporter type 1, transmembrane domain MetI-like (16.8%) Solute-binding protein family 3/N-terminal domain of MltF (16.8%) Amino acid ABC transporter, permease protein, 3-TM domain (16.8%)" MAPSMPELVETSSNLALVELGEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.3%) IPR002933 (33.3%) IPR011650 (33.3%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (33.3%) Peptidase M20, dimerisation domain (33.3%)" MLFVLAK root "1.-.-.- (16.7%) 1.1.99.2 (16.7%) 2.3.1.- (16.7%)" "Oxidoreductases (16.7%) L-2-hydroxyglutarate dehydrogenase (16.7%) Transferring groups other than amino-acyl groups (16.7%)" "GO:0009314 (1.8%) GO:0042276 (1.8%) GO:0055085 (1.8%)" "GO:0005886 (41.6%) GO:0005634 (3.2%) GO:0016020 (2.7%)" "GO:0003677 (1.8%) GO:0003684 (1.8%) GO:0003887 (1.8%)" "response to radiation (1.8%) error-prone translesion synthesis (1.8%) transmembrane transport (1.8%)" "plasma membrane (41.6%) nucleus (3.2%) membrane (2.7%)" "DNA binding (1.8%) damaged DNA binding (1.8%) DNA-directed DNA polymerase activity (1.8%)" "IPR015867 (15.7%) IPR019264 (15.7%) IPR051461 (15.7%)" "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (15.7%) Domain of unknown function DUF2179 (15.7%) UPF0750 membrane-associated protein (15.7%)" SADANSCFSDLFYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.8%) IPR011990 (32.6%) IPR012944 (32.6%)" "SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (32.6%) RagB/SusD domain (32.6%)" VLYVWFDAPLGYLSNTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0004825 (16.7%) GO:0005524 (16.7%) GO:0000049 (16.5%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "methionine-tRNA ligase activity (16.7%) ATP binding (16.7%) tRNA binding (16.5%)" "IPR015413 (8.4%) IPR023458 (8.4%) IPR014758 (8.4%)" "Methionyl/Leucyl tRNA synthetase (8.4%) Methionine-tRNA ligase, type 1 (8.4%) Methionyl-tRNA synthetase (8.4%)" VSSQYDLENENLEER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.5.1 (100%) dGTPase (100%) GO:0006203 (50%) GO:0008832 (50%) dGTP catabolic process (50%) dGTPase activity (50%) "IPR003607 (14.5%) IPR006261 (14.5%) IPR006674 (14.5%)" "HD/PDEase domain (14.5%) dGTP triphosphohydrolase (14.5%) HD domain (14.5%)" ELAELEMR root "1.2.1.8 (79.3%) 2.7.13.3 (10.3%) 3.4.21.53 (6.9%)" "betaine-aldehyde dehydrogenase (79.3%) histidine kinase (10.3%) endopeptidase La (6.9%)" "GO:0019285 (7.8%) GO:0006355 (4.9%) GO:0006260 (0.7%)" "GO:0070161 (6%) GO:0005829 (4.1%) GO:0032993 (4.1%)" "GO:0015562 (11.2%) GO:0008802 (7.8%) GO:0046872 (7.8%)" "glycine betaine biosynthetic process from choline (7.8%) regulation of DNA-templated transcription (4.9%) DNA replication (0.7%)" "anchoring junction (6%) cytosol (4.1%) protein-DNA complex (4.1%)" "efflux transmembrane transporter activity (11.2%) betaine-aldehyde dehydrogenase (NAD+) activity (7.8%) metal ion binding (7.8%)" "IPR003423 (5.7%) IPR050737 (5.7%) IPR011264 (4%)" "Outer membrane efflux protein (5.7%) Unknown (5.7%) Betaine aldehyde dehydrogenase (4%)" DFNYYVNVNGAYNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" TVSMVVDR root 2.7.1.48 (100%) uridine/cytidine kinase (100%) "GO:0044206 (17.8%) GO:0044211 (17.8%)" GO:0005737 (18.2%) "GO:0005524 (18.2%) GO:0004849 (17.8%) GO:0043771 (9.3%)" "UMP salvage (17.8%) CTP salvage (17.8%)" cytoplasm (18.2%) "ATP binding (18.2%) uridine kinase activity (17.8%) cytidine kinase activity (9.3%)" "IPR000764 (24.9%) IPR006083 (24.9%) IPR027417 (24.9%)" "Uridine kinase-like (24.9%) Phosphoribulokinase/uridine kinase (24.9%) P-loop containing nucleoside triphosphate hydrolase (24.9%)" AGTQLGEPELLFEKLEDEVLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" TLHGLTVVLSPLQSLMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.6.2.4 (96.7%) 3.6.4.12 (3.3%)" "DNA 3'-5' helicase (96.7%) DNA helicase (3.3%)" "GO:0006281 (10%) GO:0006310 (10%)" "GO:0005737 (10%) GO:0030894 (10%) GO:0043590 (10%)" "GO:0003676 (10%) GO:0005524 (10%) GO:0009378 (10%)" "DNA repair (10%) DNA recombination (10%)" "cytoplasm (10%) replisome (10%) bacterial nucleoid (10%)" "nucleic acid binding (10%) ATP binding (10%) four-way junction helicase activity (10%)" "IPR011545 (14.6%) IPR014001 (14.6%) IPR001650 (14.1%)" "DEAD/DEAH-box helicase domain (14.6%) Helicase superfamily 1/2, ATP-binding domain (14.6%) Helicase, C-terminal domain-like (14.1%)" LVTEMVEDPETGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (20%) "GO:0016651 (20%) GO:0046872 (20%) GO:0048038 (20%)" membrane (20%) "oxidoreductase activity, acting on NAD(P)H (20%) metal ion binding (20%) quinone binding (20%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" TLANNYDEFFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR040572 (100%) Thaumarchaeal output domain 1 (100%) LGVMLAGSVQNVFR Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.7%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.7%)" SLPQAMAQTDFVCSSVNVGSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) ATYSYAGR Bacteria Bacteria "1.3.1.106 (52.9%) 1.3.1.54 (47.1%)" "cobalt-precorrin-6A reductase (52.9%) precorrin-6A reductase (47.1%)" GO:0009236 (32.3%) GO:0009279 (30.6%) "GO:0016994 (32.3%) GO:0008234 (4.8%)" cobalamin biosynthetic process (32.3%) cell outer membrane (30.6%) "precorrin-6A reductase activity (32.3%) cysteine-type peptidase activity (4.8%)" "IPR003723 (12.7%) IPR012910 (12%) IPR023996 (12%)" "Precorrin-6x reductase (12.7%) TonB-dependent receptor, plug domain (12%) TonB-dependent outer membrane protein, SusC/RagA (12%)" LAGGYYVSGEASYLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (48.1%) "GO:0004553 (48.1%) GO:0016787 (3.7%)" carbohydrate metabolic process (48.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.1%) hydrolase activity (3.7%)" "IPR032291 (21.4%) IPR050727 (21.4%) IPR046780 (20%)" "Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (21.4%) Glycosyl hydrolase 43 family arabinanases (21.4%) Atrophied bacterial Ig domain (20%)" LCALYVDKLETMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) FGGATGNYNAHHVAYPQYDWK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (25.7%) GO:0044208 (25.7%) GO:0006188 (5.6%)" "GO:0004018 (31.3%) GO:0070626 (11.2%)" "'de novo' IMP biosynthetic process (25.7%) 'de novo' AMP biosynthetic process (25.7%) IMP biosynthetic process (5.6%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (31.3%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (11.2%)" "IPR000362 (12.5%) IPR004769 (12.5%) IPR008948 (12.5%)" "Fumarate lyase family (12.5%) Adenylosuccinate lyase (12.5%) L-Aspartase-like (12.5%)" NLSWEETTER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.99.19 (100%) 2-iminoacetate synthase (100%) GO:0009228 (24%) "GO:0005506 (25.3%) GO:0051539 (25.3%) GO:0003824 (24%)" thiamine biosynthetic process (24%) "iron ion binding (25.3%) 4 iron, 4 sulfur cluster binding (25.3%) catalytic activity (24%)" "IPR007197 (20%) IPR010722 (20%) IPR012726 (20%)" "Radical SAM (20%) Biotin and thiamin synthesis-associated domain (20%) Thiazole biosynthesis ThiH (20%)" EELYELLGDFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (80%) GO:0016740 (20%)" "glycosyltransferase activity (80%) transferase activity (20%)" "IPR000836 (26.6%) IPR017932 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (26.6%) Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%)" DNEALTLK root "3.2.1.143 (60%) 3.1.13.- (40%)" "poly(ADP-ribose) glycohydrolase (60%) Exoribonucleases producing 5'-phosphomonoesters (40%)" "GO:0005975 (5.7%) GO:0006282 (5.7%) GO:0009225 (5.7%)" "GO:0005634 (5.7%) GO:0005737 (5.7%) GO:0031966 (5.7%)" "GO:0004649 (5.7%) GO:0000287 (3.8%) GO:0003676 (3.8%)" "carbohydrate metabolic process (5.7%) regulation of DNA repair (5.7%) nucleotide-sugar metabolic process (5.7%)" "nucleus (5.7%) cytoplasm (5.7%) mitochondrial membrane (5.7%)" "poly(ADP-ribose) glycohydrolase activity (5.7%) magnesium ion binding (3.8%) nucleic acid binding (3.8%)" "IPR025396 (14%) IPR007667 (6%) IPR007724 (6%)" "Protein of unknown function DUF4302 (14%) Hypoxia induced protein, domain (6%) Poly(ADP-ribose) glycohydrolase (6%)" QAVFLLK root "6.3.2.25 (40.6%) 4.6.1.2 (21.9%) 3.4.21.92 (18.8%)" "tubulin--tyrosine ligase (40.6%) guanylate cyclase (21.9%) endopeptidase Clp (18.8%)" "GO:0034605 (13%) GO:0006508 (13%) GO:0043335 (12.9%)" "GO:0005737 (13.1%) GO:0005886 (1%) GO:0016020 (0.4%)" "GO:0005524 (13.5%) GO:0016887 (13%) GO:0008233 (12.8%)" "cellular response to heat (13%) proteolysis (13%) protein unfolding (12.9%)" "cytoplasm (13.1%) plasma membrane (1%) membrane (0.4%)" "ATP binding (13.5%) ATP hydrolysis activity (13%) peptidase activity (12.8%)" "IPR027417 (7.8%) IPR004176 (7.7%) IPR036628 (7.7%)" "P-loop containing nucleoside triphosphate hydrolase (7.8%) Clp, repeat (R) N-terminal domain (7.7%) Clp, N-terminal domain superfamily (7.7%)" NHQEYMQFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TEEYYMANNNR Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (10.7%) GO:0004386 (0.2%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (10.7%) helicase activity (0.2%)" "IPR000185 (7.8%) IPR011115 (7.8%) IPR014001 (7.8%)" "Protein translocase subunit SecA (7.8%) SecA DEAD-like, N-terminal (7.8%) Helicase superfamily 1/2, ATP-binding domain (7.8%)" LVMDMLFNHCGFEHPWVADMPSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" VQLVDNNNGER Bacteria Bacteria 4.1.1.11 (100%) aspartate 1-decarboxylase (100%) "GO:0006523 (25%) GO:0015940 (25%)" GO:0005829 (25%) GO:0004068 (25%) "alanine biosynthetic process (25%) pantothenate biosynthetic process (25%)" cytosol (25%) aspartate 1-decarboxylase activity (25%) "IPR003190 (50%) IPR009010 (50%)" "Aspartate decarboxylase (50%) Aspartate decarboxylase-like domain superfamily (50%)" ALVNEPEVLLLDEPLAALDLK Bacteria Bacteria 7.6.2.11 (100%) ABC-type polyamine transporter (100%) "GO:0043190 (24.8%) GO:0005886 (0.1%) GO:0032991 (0.1%)" "GO:0005524 (25.1%) GO:0016887 (24.9%) GO:0015594 (24.8%)" "ATP-binding cassette (ABC) transporter complex (24.8%) plasma membrane (0.1%) protein-containing complex (0.1%)" "ATP binding (25.1%) ATP hydrolysis activity (24.9%) ABC-type putrescine transporter activity (24.8%)" "IPR003439 (11.1%) IPR003593 (11.1%) IPR050093 (11.1%)" "ABC transporter-like, ATP-binding domain (11.1%) AAA+ ATPase domain (11.1%) ABC Transporter, Small Molecule Importer (11.1%)" EVHPTCMCSVPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (33.3%) IPR020845 (33.3%) IPR042099 (33.3%)" "AMP-dependent synthetase/ligase domain (33.3%) AMP-binding, conserved site (33.3%) ANL, N-terminal domain (33.3%)" TTFNLGNYYGSGGAAELTSPWESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLLTSCLDNLLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.2.1.38 (100%) N-acetyl-gamma-glutamyl-phosphate reductase (100%) GO:0006526 (20.1%) GO:0005737 (19.7%) "GO:0003942 (20.1%) GO:0051287 (20.1%) GO:0070401 (20.1%)" L-arginine biosynthetic process (20.1%) cytoplasm (19.7%) "N-acetyl-gamma-glutamyl-phosphate reductase activity (20.1%) NAD binding (20.1%) NADP+ binding (20.1%)" "IPR000534 (20.1%) IPR000706 (20.1%) IPR023013 (20.1%)" "Semialdehyde dehydrogenase, NAD-binding (20.1%) N-acetyl-gamma-glutamyl-phosphate reductase, type 1 (20.1%) N-acetyl-gamma-glutamyl-phosphate reductase, active site (20.1%)" EYDTGNYVVTLNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LDLDANVLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NEVLGQQEVWNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006261 (50%) GO:0016740 (50%) DNA-templated DNA replication (50%) transferase activity (50%) "IPR050238 (51.3%) IPR027417 (48.7%)" "DNA Replication and Repair Clamp Loader Complex (51.3%) P-loop containing nucleoside triphosphate hydrolase (48.7%)" RSFDVNLFSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001383 (25%) IPR026569 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL28, bacteria (25%) Large ribosomal subunit protein bL28 (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" DNLQLPENAFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0035673 (50%) membrane (50%) oligopeptide transmembrane transporter activity (50%) "IPR004813 (33.3%) IPR004814 (33.3%) IPR045035 (33.3%)" "Oligopeptide transporter, OPT superfamily (33.3%) Oligopeptide transporter OPT (33.3%) Metal-nicotianamine transporter YSL-like (33.3%)" LDGSNHQYTGVGGNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLGGLPDWGELYQLLTNHTSYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR016769 (33.3%) IPR023214 (33.3%) IPR036412 (33.3%)" "Bacteriophage SP01, Orf1 (33.3%) HAD superfamily (33.3%) HAD-like superfamily (33.3%)" YLNLPMEELAQLALASLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.2%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.2%)" ADALAACEDLLASGEFSLVPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FTGAYDLR root "GO:0006357 (1.9%) GO:0006865 (1.9%) GO:0009239 (1.9%)" "GO:0009279 (67.3%) GO:0005634 (1.9%) GO:0005829 (1.9%)" "GO:0005506 (1.9%) GO:0008270 (1.9%) GO:0016491 (1.9%)" "regulation of transcription by RNA polymerase II (1.9%) amino acid transport (1.9%) enterobactin biosynthetic process (1.9%)" "cell outer membrane (67.3%) nucleus (1.9%) cytosol (1.9%)" "iron ion binding (1.9%) zinc ion binding (1.9%) oxidoreductase activity (1.9%)" "IPR012944 (29.4%) IPR033985 (29.4%) IPR011990 (26.9%)" "RagB/SusD domain (29.4%) SusD-like, N-terminal (29.4%) Tetratricopeptide-like helical domain superfamily (26.9%)" EQFDESVNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) "GO:0016036 (7.8%) GO:0007234 (7.1%)" "GO:0005886 (20.8%) GO:0016020 (0.6%)" "GO:0000155 (21.4%) GO:0005524 (20.1%) GO:0004721 (7.8%)" "cellular response to phosphate starvation (7.8%) osmosensory signaling via phosphorelay pathway (7.1%)" "plasma membrane (20.8%) membrane (0.6%)" "phosphorelay sensor kinase activity (21.4%) ATP binding (20.1%) phosphoprotein phosphatase activity (7.8%)" "IPR003661 (15.1%) IPR003594 (14.9%) IPR005467 (14.9%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (15.1%) Histidine kinase/HSP90-like ATPase domain (14.9%) Histidine kinase domain (14.9%)" SVANYCDTFQYMLDFVNDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella HFDADALNSYLNLQLLPYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (51.2%) IPR012547 (34.9%) IPR027417 (14%)" "AAA-ATPase-like domain (51.2%) PD-(D/E)XK nuclease superfamily 9 (34.9%) P-loop containing nucleoside triphosphate hydrolase (14%)" NSSFYTLK root "1.1.1.35 (40%) 4.2.1.17 (40%) 2.7.1.92 (20%)" "3-hydroxyacyl-CoA dehydrogenase (40%) enoyl-CoA hydratase (40%) 5-dehydro-2-deoxygluconokinase (20%)" GO:0006635 (8.2%) GO:0016020 (2%) "GO:0016301 (61.2%) GO:0070403 (8.2%) GO:0003857 (6.1%)" fatty acid beta-oxidation (8.2%) membrane (2%) "kinase activity (61.2%) NAD+ binding (8.2%) (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity (6.1%)" "IPR011611 (25.6%) IPR052700 (25.6%) IPR029056 (24%)" "Carbohydrate kinase PfkB (25.6%) Carbohydrate kinase PfkB-like (25.6%) Ribokinase-like (24%)" HGVQLDWLQVTTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" QPVDLFELHDGLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000036 (50%) GO:0016297 (50%)" "acyl carrier activity (50%) fatty acyl-[ACP] hydrolase activity (50%)" "IPR045023 (25.6%) IPR049427 (25.6%) IPR002864 (24.4%)" "Acyl-[acyl-carrier-protein] hydrolase FATA/B (25.6%) Acyl-ACP thioesterase-like, C-terminal domain (25.6%) Acyl-ACP thioesterase, N-terminal hotdog domain (24.4%)" SGGYSYTYFLPGPLGVNLGMLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (33.3%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (33.3%)" "IPR003741 (14.3%) IPR004452 (14.3%) IPR009051 (14.3%)" "LUD domain (14.3%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.3%) Alpha-helical ferredoxin (14.3%)" LQLADGSLYNHPGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" ELVTQDDLPYLVSDVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.5%) IPR002034 (14.5%) IPR013709 (14.5%)" "Pyruvate carboxyltransferase (14.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.5%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.5%)" MGGEMDYLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (26.5%) IPR050280 (26.5%) IPR027304 (23.5%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (26.5%) Outer Membrane Protein Chaperone SurA (26.5%) Trigger factor/SurA domain superfamily (23.5%)" KYHAHDENNEANVGDTVMLMETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000266 (25%) IPR012340 (25%) IPR019979 (25%)" "Small ribosomal subunit protein uS17 (25%) Nucleic acid-binding, OB-fold (25%) Small ribosomal subunit protein uS17, conserved site (25%)" VLLNDAAEGTDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019698 (50%) GO:0016829 (50%) D-galacturonate catabolic process (50%) lyase activity (50%) "IPR007392 (20.2%) IPR013974 (20.2%) IPR044144 (20.2%)" "D-galactarate/Altronate dehydratase, second domain (20.2%) SAF domain (20.2%) UxaA/GarD, SAF domain (20.2%)" TVELEGVVYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" ADMFNDHVGGLSVFVYDEQGNFLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) ALSYSMTSFFTTGGLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.4.-.- (88.1%) 2.4.1.- (11.9%)" "Glycosyltransferases (88.1%) Hexosyltransferases (11.9%)" GO:0016020 (54.9%) "GO:0016740 (30.5%) GO:0016757 (14.2%) GO:0016758 (0.4%)" membrane (54.9%) "transferase activity (30.5%) glycosyltransferase activity (14.2%) hexosyltransferase activity (0.4%)" "IPR001173 (33.8%) IPR050834 (33.2%) IPR029044 (33%)" "Glycosyltransferase 2-like (33.8%) Glycosyltransferase 2 family enzymes (33.2%) Nucleotide-diphospho-sugar transferases (33%)" FSVLTPVGLLPLAVAGFDVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.3%) GO:0006096 (14.3%) GO:0051156 (14.3%)" GO:0005829 (14.3%) "GO:0004347 (14.3%) GO:0048029 (14.3%) GO:0097367 (13.9%)" "gluconeogenesis (14.3%) glycolytic process (14.3%) glucose 6-phosphate metabolic process (14.3%)" cytosol (14.3%) "glucose-6-phosphate isomerase activity (14.3%) monosaccharide binding (14.3%) carbohydrate derivative binding (13.9%)" "IPR001672 (20.2%) IPR018189 (20.2%) IPR035482 (20.2%)" "Phosphoglucose isomerase (PGI) (20.2%) Phosphoglucose isomerase, conserved site (20.2%) Phosphoglucose isomerase, SIS domain 2 (20.2%)" WLFQGTYYLPER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) DKSTVSVLSPEVYAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001684 (53.3%) IPR018261 (46.7%)" "Large ribosomal subunit protein bL27 (53.3%) Large ribosomal subunit protein bL27, conserved site (46.7%)" TGFNTANSSWLWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.7%) IPR012944 (32.1%) IPR033985 (32.1%)" "Tetratricopeptide-like helical domain superfamily (35.7%) RagB/SusD domain (32.1%) SusD-like, N-terminal (32.1%)" VDELELTDYNDEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.25 (100%) tRNA pseudouridine(55) synthase (100%) "GO:1990481 (21.7%) GO:0031119 (19.6%) GO:0006400 (2.2%)" GO:0005634 (2.2%) "GO:0003723 (21.7%) GO:0009982 (13%) GO:0140098 (10.9%)" "mRNA pseudouridine synthesis (21.7%) tRNA pseudouridine synthesis (19.6%) tRNA modification (2.2%)" nucleus (2.2%) "RNA binding (21.7%) pseudouridine synthase activity (13%) catalytic activity, acting on RNA (10.9%)" "IPR002501 (25%) IPR014780 (25%) IPR020103 (25%)" "Pseudouridine synthase II, N-terminal (25%) tRNA pseudouridine synthase II, TruB (25%) Pseudouridine synthase, catalytic domain superfamily (25%)" TPHVEYLLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (50.6%) IPR027417 (49.1%) IPR023214 (0.4%)" "Tetraacyldisaccharide 4'-kinase (50.6%) P-loop containing nucleoside triphosphate hydrolase (49.1%) HAD superfamily (0.4%)" KQEVVTGVDESTGLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" TYATGNYQLWNTFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (46.2%) "GO:0004553 (46.2%) GO:0016787 (7.7%)" carbohydrate metabolic process (46.2%) "hydrolase activity, hydrolyzing O-glycosyl compounds (46.2%) hydrolase activity (7.7%)" "IPR032291 (21.9%) IPR050727 (21.9%) IPR006710 (18.8%)" "Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (21.9%) Glycosyl hydrolase 43 family arabinanases (21.9%) Glycoside hydrolase, family 43 (18.8%)" EEEDSFLR root 6.1.1.7 (100%) alanine--tRNA ligase (100%) "GO:0006419 (13.6%) GO:0000462 (0.1%) GO:0000479 (0.1%)" "GO:0005737 (13.6%) GO:0005886 (0.2%) GO:0016020 (0.2%)" "GO:0005524 (13.7%) GO:0000049 (13.6%) GO:0002161 (13.6%)" "alanyl-tRNA aminoacylation (13.6%) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.1%) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.1%)" "cytoplasm (13.6%) plasma membrane (0.2%) membrane (0.2%)" "ATP binding (13.7%) tRNA binding (13.6%) aminoacyl-tRNA deacylase activity (13.6%)" "IPR018164 (8.8%) IPR018165 (8.8%) IPR050058 (8.8%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (8.8%) Alanyl-tRNA synthetase, class IIc, core domain (8.8%) Alanine--tRNA ligase (8.8%)" NQQLSVMAGTYGFGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006826 (47%) GO:0006811 (3%)" GO:0009279 (50%) "iron ion transport (47%) monoatomic ion transport (3%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" PKDYVTTSDDPQQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.- (100%) Transferring other groups (100%) "GO:0000455 (32.8%) GO:0001522 (0.3%) GO:0006364 (0.3%)" "GO:0003723 (33.1%) GO:0120159 (32.8%) GO:0009982 (0.3%)" "enzyme-directed rRNA pseudouridine synthesis (32.8%) pseudouridine synthesis (0.3%) rRNA processing (0.3%)" "RNA binding (33.1%) rRNA pseudouridine synthase activity (32.8%) pseudouridine synthase activity (0.3%)" "IPR000748 (11.2%) IPR006145 (11.2%) IPR050343 (11.2%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.2%) Pseudouridine synthase, RsuA/RluA-like (11.2%) Ribosomal RNA Pseudouridine Synthase RsuA (11.2%)" VVLTWAPHCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.11 (100%) N-succinylornithine carbamoyltransferase (100%) "GO:0019240 (25%) GO:0042450 (25%)" "GO:0004585 (25%) GO:0016597 (25%)" "citrulline biosynthetic process (25%) L-arginine biosynthetic process via ornithine (25%)" "ornithine carbamoyltransferase activity (25%) amino acid binding (25%)" "IPR006131 (20.1%) IPR006132 (20.1%) IPR043696 (20.1%)" "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.1%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20.1%) N-succinylornithine carbamoyltransferase ArgF'-like (20.1%)" EQLELSR root "2.7.7.6 (60.6%) 2.3.1.8 (6.1%) 2.7.13.3 (4.9%)" "DNA-directed RNA polymerase (60.6%) phosphate acetyltransferase (6.1%) histidine kinase (4.9%)" "GO:0006351 (10.2%) GO:0031122 (1.3%) GO:0042060 (1.3%)" "GO:0000428 (10%) GO:0005737 (2.8%) GO:0005886 (2.1%)" "GO:0003677 (13.6%) GO:0003899 (10.1%) GO:0003700 (1.9%)" "DNA-templated transcription (10.2%) cytoplasmic microtubule organization (1.3%) wound healing (1.3%)" "DNA-directed RNA polymerase complex (10%) cytoplasm (2.8%) plasma membrane (2.1%)" "DNA binding (13.6%) DNA-directed RNA polymerase activity (10.1%) DNA-binding transcription factor activity (1.9%)" "IPR006110 (9.5%) IPR036161 (3.3%) IPR036388 (3.1%)" "RNA polymerase, subunit omega/Rpo6/RPB6 (9.5%) RPB6/omega subunit-like superfamily (3.3%) Winged helix-like DNA-binding domain superfamily (3.1%)" VSLFVDDNKLSPEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (25%) GO:0005737 (25%) "GO:0046872 (25%) GO:0070006 (25%)" proteolysis (25%) cytoplasm (25%) "metal ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000587 (12.6%) IPR000994 (12.6%) IPR001131 (12.6%)" "Creatinase, N-terminal (12.6%) Peptidase M24 (12.6%) Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site (12.6%)" SLENGQVEGDAAELNDYKGQLLAWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LSEAEYHSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (31.9%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (31.9%)" LGDANLEAPQLGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (33.3%) "GO:0008171 (33.3%) GO:0008757 (33.3%)" methylation (33.3%) "O-methyltransferase activity (33.3%) S-adenosylmethionine-dependent methyltransferase activity (33.3%)" "IPR002935 (33.3%) IPR029063 (33.3%) IPR050362 (33.3%)" "Class I-like SAM-dependent O-methyltransferase (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%) Cation-dependent O-methyltransferase (33.3%)" YSTAWAYDLLQDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.4%) "GO:0000155 (26.1%) GO:0003700 (24.4%) GO:0043565 (24.4%)" membrane (24.4%) "phosphorelay sensor kinase activity (26.1%) DNA-binding transcription factor activity (24.4%) sequence-specific DNA binding (24.4%)" "IPR011110 (15.6%) IPR015943 (15.1%) IPR011123 (14.1%)" "Two component regulator propeller (15.6%) WD40/YVTN repeat-like-containing domain superfamily (15.1%) Two component regulator three Y (14.1%)" YYVSGELYNQGSLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TDALVQTVLTWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.5%) IPR002034 (14.5%) IPR013709 (14.5%)" "Pyruvate carboxyltransferase (14.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.5%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.5%)" LQVFHGYAAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (34%) IPR043148 (33%) IPR051612 (33%)" "CDP-glycerol glycerophosphotransferase (34%) CDP-glycerol glycerophosphotransferase, C-terminal domain (33%) Teichoic Acid Biosynthesis Enzymes (33%)" EKFPELHLDGELQADAALVPEVAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (59.3%) GO:0008959 (40.7%)" "acetyltransferase activity (59.3%) phosphate acetyltransferase activity (40.7%)" "IPR002505 (17%) IPR004614 (17%) IPR050500 (17%)" "Phosphate acetyl/butaryl transferase (17%) Phosphate acetyltransferase (17%) Phosphate Acetyltransferase/Butyryltransferase (17%)" LGADVTLVYR root "1.4.1.13 (69.4%) 1.8.1.7 (27.8%) 1.8.-.- (2.8%)" "glutamate synthase (NADPH) (69.4%) glutathione-disulfide reductase (27.8%) Acting on a sulfur group of donors (2.8%)" "GO:0006749 (3.8%) GO:0034599 (3.8%) GO:0045454 (3.8%)" "GO:0005829 (3.8%) GO:0016020 (1.5%) GO:0005739 (0.4%)" "GO:0051536 (35%) GO:0016491 (27.7%) GO:0004355 (8.8%)" "glutathione metabolic process (3.8%) cellular response to oxidative stress (3.8%) cell redox homeostasis (3.8%)" "cytosol (3.8%) membrane (1.5%) mitochondrion (0.4%)" "iron-sulfur cluster binding (35%) oxidoreductase activity (27.7%) glutamate synthase (NADPH) activity (8.8%)" "IPR023753 (12%) IPR036188 (11.9%) IPR028261 (10.5%)" "FAD/NAD(P)-binding domain (12%) FAD/NAD(P)-binding domain superfamily (11.9%) Dihydroprymidine dehydrogenase domain II (10.5%)" EPLVQVLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (73.9%) IPR008160 (26.1%)" "Domain of unknown function DUF4988 (73.9%) Collagen triple helix repeat (26.1%)" KVAPNHFLLVPGVGAQGGSLQEVCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.23 (100%) orotidine-5'-phosphate decarboxylase (100%) "GO:0006207 (33.3%) GO:0044205 (31.6%) GO:0009220 (1.8%)" GO:0004590 (33.3%) "'de novo' pyrimidine nucleobase biosynthetic process (33.3%) 'de novo' UMP biosynthetic process (31.6%) pyrimidine ribonucleotide biosynthetic process (1.8%)" orotidine-5'-phosphate decarboxylase activity (33.3%) "IPR001754 (25.7%) IPR011995 (25.7%) IPR011060 (24.3%)" "Orotidine 5'-phosphate decarboxylase domain (25.7%) Orotidine 5'-phosphate decarboxylase, type 2 (25.7%) Ribulose-phosphate binding barrel (24.3%)" LLRPTVEGLAEENLDYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0006189 (20%) GO:0009113 (20%)" "GO:0004637 (20%) GO:0005524 (20%) GO:0046872 (20%)" "'de novo' IMP biosynthetic process (20%) purine nucleobase biosynthetic process (20%)" "phosphoribosylamine-glycine ligase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000115 (11.4%) IPR011761 (11.4%) IPR020560 (11.4%)" "Phosphoribosylglycinamide synthetase (11.4%) ATP-grasp fold (11.4%) Phosphoribosylglycinamide synthetase, C-domain (11.4%)" FNVLTSSCLPLPLENVDTDQLLPAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" FGQHDVTAMGLFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" SSLPFGAPDFSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (50%) 3.4.24.- (50%)" "Acting on peptide bonds (peptidases) (50%) Metalloendopeptidases (50%)" GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.4%) IPR034005 (20.4%) IPR045090 (20.4%)" "Peptidase M3A/M3B catalytic domain (20.4%) Peptidyl-dipeptidase DCP (20.4%) Peptidase M3A/M3B (20.4%)" FGEDLDFSLR Pseudomonadati Bacteria Pseudomonadati "2.4.-.- (79%) 2.4.1.- (17.4%) 2.4.1.293 (2.2%)" "Glycosyltransferases (79%) Hexosyltransferases (17.4%) GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase (2.2%)" GO:0016020 (52%) "GO:0016740 (27.2%) GO:0016757 (18.8%) GO:0016758 (1.9%)" membrane (52%) "transferase activity (27.2%) glycosyltransferase activity (18.8%) hexosyltransferase activity (1.9%)" "IPR001173 (35%) IPR029044 (34.8%) IPR050834 (29.7%)" "Glycosyltransferase 2-like (35%) Nucleotide-diphospho-sugar transferases (34.8%) Glycosyltransferase 2 family enzymes (29.7%)" NEEAGSDYSTQQSASSNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" SPNLVLLLGESFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.6.- (100%) Sulfuric ester hydrolases (100%) GO:0009244 (32.9%) GO:0005886 (32.9%) "GO:0016776 (32.9%) GO:0016787 (1.2%)" lipopolysaccharide core region biosynthetic process (32.9%) plasma membrane (32.9%) "phosphotransferase activity, phosphate group as acceptor (32.9%) hydrolase activity (1.2%)" "IPR000917 (26%) IPR040423 (26%) IPR012549 (24%)" "Sulfatase, N-terminal (26%) Phosphoethanolamine transferase (26%) Phosphoethanolamine transferase, N-terminal (24%)" NFFFLSFK root "GO:0006353 (6.3%) GO:0010591 (6.3%) GO:0010976 (6.3%)" "GO:0005634 (6.3%) GO:0005884 (6.3%) GO:0030016 (6.3%)" "GO:0003785 (6.3%) GO:0043168 (6.3%) GO:0051015 (6.3%)" "DNA-templated transcription termination (6.3%) regulation of lamellipodium assembly (6.3%) positive regulation of neuron projection development (6.3%)" "nucleus (6.3%) actin filament (6.3%) myofibril (6.3%)" "actin monomer binding (6.3%) anion binding (6.3%) actin filament binding (6.3%)" "IPR001680 (16.7%) IPR002108 (16.7%) IPR015943 (16.7%)" "WD40 repeat (16.7%) Actin-depolymerising factor homology domain (16.7%) WD40/YVTN repeat-like-containing domain superfamily (16.7%)" EVFLPAFDELKDCLQMAAYLLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (33.3%) GO:0005829 (33.3%) GO:0004056 (33.3%) L-arginine biosynthetic process via ornithine (33.3%) cytosol (33.3%) argininosuccinate lyase activity (33.3%) "IPR009049 (17.1%) IPR020557 (17.1%) IPR022761 (17.1%)" "Argininosuccinate lyase (17.1%) Fumarate lyase, conserved site (17.1%) Fumarate lyase, N-terminal (17.1%)" YDLSSLEYCTTAGEAMNPSVAETFQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006633 (16.7%) GO:0006637 (16.7%)" "GO:0004321 (16.7%) GO:0005524 (16.7%) GO:0015645 (16.7%)" "fatty acid biosynthetic process (16.7%) acyl-CoA metabolic process (16.7%)" "fatty-acyl-CoA synthase activity (16.7%) ATP binding (16.7%) fatty acid ligase activity (16.7%)" "IPR000873 (16.8%) IPR020845 (16.8%) IPR025110 (16.8%)" "AMP-dependent synthetase/ligase domain (16.8%) AMP-binding, conserved site (16.8%) AMP-binding enzyme, C-terminal domain (16.8%)" YTLPSDVKLLSQTLLEELAEQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (33.3%) IPR012334 (33.3%) IPR033427 (33.3%)" "Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%) Domain of unknown function DUF5123 (33.3%)" FDEEALDYLVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0051301 (10.5%) GO:0051603 (10.5%)" GO:0009376 (10.5%) "GO:0005524 (10.5%) GO:0008233 (10.5%) GO:0016887 (10.5%)" "cell division (10.5%) proteolysis involved in protein catabolic process (10.5%)" HslUV protease complex (10.5%) "ATP binding (10.5%) peptidase activity (10.5%) ATP hydrolysis activity (10.5%)" "IPR019489 (12.1%) IPR027417 (12.1%) IPR050052 (12.1%)" "Clp ATPase, C-terminal (12.1%) P-loop containing nucleoside triphosphate hydrolase (12.1%) ATP-dependent Clp protease ATP-binding subunit ClpX (12.1%)" NTYDLVSAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" VSLPVPDK root "3.4.-.- (85.7%) 2.3.2.8 (14.3%)" "Acting on peptide bonds (peptidases) (85.7%) arginyltransferase (14.3%)" "GO:0006508 (43.6%) GO:0005975 (0.9%) GO:0006950 (0.9%)" "GO:0005737 (0.9%) GO:0016020 (0.9%) GO:0055052 (0.9%)" "GO:0008233 (41.8%) GO:0004190 (1.8%) GO:0005524 (1.8%)" "proteolysis (43.6%) carbohydrate metabolic process (0.9%) response to stress (0.9%)" "cytoplasm (0.9%) membrane (0.9%) ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing (0.9%)" "peptidase activity (41.8%) aspartic-type endopeptidase activity (1.8%) ATP binding (1.8%)" "IPR001539 (37.4%) IPR051454 (37.4%) IPR001969 (1.6%)" "Peptidase U32 (37.4%) RNA and ubiquinone modification enzymes (37.4%) Aspartic peptidase, active site (1.6%)" VNEVFNDVFYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.4 (100%) cellulase (100%) "GO:0030245 (23.6%) GO:0045493 (21.1%)" "GO:0004553 (23.6%) GO:0030246 (22.8%) GO:0016829 (8.9%)" "cellulose catabolic process (23.6%) xylan catabolic process (21.1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (23.6%) carbohydrate binding (22.8%) lyase activity (8.9%)" "IPR002037 (13.9%) IPR005084 (13.5%) IPR008928 (13%)" "Glycoside hydrolase, family 8 (13.9%) Carbohydrate binding module family 6 (13.5%) Six-hairpin glycosidase superfamily (13%)" RLGFDFAANFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" KDFLEDCVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.11.4 (100%) tripeptide aminopeptidase (100%) "GO:0006508 (16.7%) GO:0043171 (16.7%)" GO:0005829 (16.7%) "GO:0008237 (16.7%) GO:0008270 (16.7%) GO:0045148 (16.7%)" "proteolysis (16.7%) peptide catabolic process (16.7%)" cytosol (16.7%) "metallopeptidase activity (16.7%) zinc ion binding (16.7%) tripeptide aminopeptidase activity (16.7%)" "IPR001261 (20.5%) IPR002933 (20.5%) IPR010161 (20.5%)" "ArgE/DapE/ACY1/CPG2/YscS, conserved site (20.5%) Peptidase M20 (20.5%) Peptidase M20B, tripeptide aminopeptidase (20.5%)" FGLSYQLDEQGSNVYATVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (42.6%) GO:0006811 (4.3%) GO:0044718 (2.1%)" GO:0009279 (48.9%) GO:0015344 (2.1%) "iron ion transport (42.6%) monoatomic ion transport (4.3%) siderophore transmembrane transport (2.1%)" cell outer membrane (48.9%) siderophore uptake transmembrane transporter activity (2.1%) "IPR000531 (26.1%) IPR039426 (26.1%) IPR012910 (23.9%)" "TonB-dependent receptor-like, beta-barrel (26.1%) TonB-dependent receptor-like (26.1%) TonB-dependent receptor, plug domain (23.9%)" LQEGFVVTDEPGVYFLPALLDDWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.11.9 (100%) Xaa-Pro aminopeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0030145 (25%) GO:0070006 (25%)" proteolysis (25%) cytosol (25%) "manganese ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000994 (20.4%) IPR007865 (20.4%) IPR052433 (20.4%)" "Peptidase M24 (20.4%) Aminopeptidase P, N-terminal (20.4%) Xaa-Pro dipeptidase-like (20.4%)" KDQYGEQTYAQYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" GQYSVSYNHADEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GGVSDLAYLEEVPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0008360 (48.5%) GO:0005886 (48.5%) GO:0000166 (3%) regulation of cell shape (48.5%) plasma membrane (48.5%) nucleotide binding (3%) "IPR007221 (26.2%) IPR055342 (26.2%) IPR042177 (23%)" "Rod shape-determining protein MreC (26.2%) Rod shape-determining protein MreC, beta-barrel core (26.2%) Cell/Rod shape-determining protein MreC, domain 1 (23%)" YQGGYLWDFVDQGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.5%) GO:0009341 (25.5%) "GO:0004565 (25.5%) GO:0030246 (23.5%)" lactose catabolic process (25.5%) beta-galactosidase complex (25.5%) "beta-galactosidase activity (25.5%) carbohydrate binding (23.5%)" "IPR006103 (8%) IPR032312 (8%) IPR050347 (8%)" "Glycoside hydrolase family 2, catalytic domain (8%) Beta-galactosidase, domain 4 (8%) Bacterial Beta-galactosidase (8%)" SNLLKPEGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.8%) GO:0006529 (1.3%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (23.8%) GO:0000166 (1.3%)" "L-asparagine biosynthetic process (23.8%) obsolete asparagine biosynthetic process (1.3%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (23.8%) nucleotide binding (1.3%)" "IPR004618 (35.1%) IPR006195 (33.3%) IPR045864 (31.6%)" "Aspartate--ammonia ligase (35.1%) Aminoacyl-tRNA synthetase, class II (33.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (31.6%)" NGVAYYSPDAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19.2%) "GO:0000155 (20.2%) GO:0003700 (20.2%) GO:0005524 (20.2%)" membrane (19.2%) "phosphorelay sensor kinase activity (20.2%) DNA-binding transcription factor activity (20.2%) ATP binding (20.2%)" "IPR001789 (6.8%) IPR003594 (6.8%) IPR003661 (6.8%)" "Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%)" AVSLYDNNNLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) IPR003423 (100%) Outer membrane efflux protein (100%) AVLNALGYEPANANLQKELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (81.8%) IPR008160 (18.2%)" "Domain of unknown function DUF4988 (81.8%) Collagen triple helix repeat (18.2%)" VLGLSPDASNDEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR001623 (20.5%) IPR007791 (20.5%) IPR050817 (20.5%)" "DnaJ domain (20.5%) Co-chaperone DjlA, N-terminal (20.5%) DjlA DnaK co-chaperone (20.5%)" KELSVNFK root "GO:0006633 (7.7%) GO:0009306 (7.7%) GO:0009451 (7.7%)" "GO:0005737 (7.7%) GO:0005886 (7.7%) GO:0009279 (7.7%)" "GO:0003723 (7.7%) GO:0004312 (7.7%) GO:0004315 (7.7%)" "fatty acid biosynthetic process (7.7%) protein secretion (7.7%) RNA modification (7.7%)" "cytoplasm (7.7%) plasma membrane (7.7%) cell outer membrane (7.7%)" "RNA binding (7.7%) fatty acid synthase activity (7.7%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (7.7%)" "IPR011990 (10.5%) IPR000270 (9.6%) IPR012910 (9.6%)" "Tetratricopeptide-like helical domain superfamily (10.5%) PB1 domain (9.6%) TonB-dependent receptor, plug domain (9.6%)" NLEVYGEMHR Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.4.-.- (67.9%) 2.4.2.53 (23.9%) 2.4.1.- (5.5%)" "Glycosyltransferases (67.9%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (23.9%) Hexosyltransferases (5.5%)" GO:0009103 (33.2%) GO:0005886 (33.4%) "GO:0099621 (33.4%) GO:0016757 (0.1%)" lipopolysaccharide biosynthetic process (33.2%) plasma membrane (33.4%) "undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (33.4%) glycosyltransferase activity (0.1%)" "IPR050256 (33.4%) IPR001173 (33.3%) IPR029044 (33.3%)" "Glycosyltransferase 2 (33.4%) Glycosyltransferase 2-like (33.3%) Nucleotide-diphospho-sugar transferases (33.3%)" QTANSELSASWNLQNRPEFHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000184 (50%) IPR039910 (50%)" "Bacterial surface antigen (D15) (50%) Surface antigen D15-like (50%)" GNYDVPHTDEDYDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (40%) GO:0006811 (10%)" GO:0009279 (50%) "iron ion transport (40%) monoatomic ion transport (10%)" cell outer membrane (50%) "IPR000531 (26.3%) IPR012910 (26.3%) IPR039426 (26.3%)" "TonB-dependent receptor-like, beta-barrel (26.3%) TonB-dependent receptor, plug domain (26.3%) TonB-dependent receptor-like (26.3%)" YVDLYKALEDLAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.3.8.1 (60%) 1.3.99.- (40%)" "short-chain acyl-CoA dehydrogenase (60%) With other acceptors (40%)" "GO:0050660 (49.7%) GO:0016627 (45.1%) GO:0003995 (3.4%)" "flavin adenine dinucleotide binding (49.7%) oxidoreductase activity, acting on the CH-CH group of donors (45.1%) acyl-CoA dehydrogenase activity (3.4%)" "IPR009075 (10%) IPR020964 (10%) IPR052166 (10%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10%) Acyl-CoA dehydrogenase, C-terminal (10%) Diverse substrate specificity acyl-CoA dehydrogenase (10%)" YTLLLSSGELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.21.10 (100%) crossover junction endodeoxyribonuclease (100%) "GO:0006281 (1.1%) GO:0006310 (1.1%)" "GO:0043190 (7.5%) GO:0005737 (1.1%) GO:0048476 (1.1%)" "GO:0005524 (38.7%) GO:0016887 (38.7%) GO:0042626 (7.5%)" "DNA repair (1.1%) DNA recombination (1.1%)" "ATP-binding cassette (ABC) transporter complex (7.5%) cytoplasm (1.1%) Holliday junction resolvase complex (1.1%)" "ATP binding (38.7%) ATP hydrolysis activity (38.7%) ATPase-coupled transmembrane transporter activity (7.5%)" "IPR003439 (19.9%) IPR003593 (19.9%) IPR017871 (19.9%)" "ABC transporter-like, ATP-binding domain (19.9%) AAA+ ATPase domain (19.9%) ABC transporter-like, conserved site (19.9%)" QWLNTNR root 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (14.7%) GO:0019676 (14.7%) GO:0006388 (2.5%)" "GO:0005634 (2.5%) GO:0005765 (1.4%) GO:0030897 (1.4%)" "GO:0046872 (14.7%) GO:0051538 (14.7%) GO:0015930 (9.8%)" "glutamate biosynthetic process (14.7%) ammonia assimilation cycle (14.7%) tRNA splicing, via endonucleolytic cleavage and ligation (2.5%)" "nucleus (2.5%) lysosomal membrane (1.4%) HOPS complex (1.4%)" "metal ion binding (14.7%) 3 iron, 4 sulfur cluster binding (14.7%) glutamate synthase activity (9.8%)" "IPR002489 (10.5%) IPR002932 (10.5%) IPR006982 (10.5%)" "Glutamate synthase, alpha subunit, C-terminal (10.5%) Glutamate synthase domain (10.5%) Glutamate synthase, central-N (10.5%)" VVVDDLVDGTLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR007066 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 3 (9.3%)" KEGFEVFVSDMSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.2.9 (100%) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase (100%) "GO:0008360 (14.4%) GO:0009252 (14.4%) GO:0051301 (14.4%)" GO:0005737 (14.4%) "GO:0005524 (14.4%) GO:0008764 (14.4%)" "regulation of cell shape (14.4%) peptidoglycan biosynthetic process (14.4%) cell division (14.4%)" cytoplasm (14.4%) "ATP binding (14.4%) UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (14.4%)" "IPR005762 (20.6%) IPR013221 (20.6%) IPR004101 (19.9%)" "UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD (20.6%) Mur ligase, central (20.6%) Mur ligase, C-terminal (19.9%)" NSLDELLAEELPNMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.3%) IPR050337 (34.3%) IPR036237 (31.4%)" "Rhamnose isomerase (34.3%) L-rhamnose isomerase (34.3%) Xylose isomerase-like superfamily (31.4%)" VLFDAVYNHTFDLNGSNFQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (51.2%) "GO:0016798 (32.5%) GO:0051060 (16.3%)" carbohydrate metabolic process (51.2%) "hydrolase activity, acting on glycosyl bonds (32.5%) pullulanase activity (16.3%)" "IPR006047 (15%) IPR011840 (14.6%) IPR049117 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (15%) Pullulanase, type I (14.6%) Pullulanase, all-beta domain (14.6%)" GEEALLSTDDSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (17.4%) GO:0006085 (15.9%)" GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0008776 (17.4%) GO:0000287 (15.9%)" "acetate metabolic process (17.4%) acetyl-CoA biosynthetic process (15.9%)" cytoplasm (15.9%) "ATP binding (17.4%) acetate kinase activity (17.4%) magnesium ion binding (15.9%)" "IPR000890 (25.3%) IPR004372 (25.3%) IPR023865 (25.3%)" "Aliphatic acid kinase, short-chain (25.3%) Acetate/propionate kinase (25.3%) Aliphatic acid kinase, short-chain, conserved site (25.3%)" SLMDNLFLYDGTEHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006412 (20%) GO:0017148 (20%)" GO:0022625 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" cytosolic large ribosomal subunit (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (25%) IPR005823 (25%) IPR023563 (25%)" "Large ribosomal subunit protein uL13 (25%) Large ribosomal subunit protein uL13, bacteria (25%) Large ribosomal subunit protein uL13, conserved site (25%)" HVYFTGLVR Bacteria Bacteria 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.1%) GO:0005829 (20.1%) "GO:0004832 (20.1%) GO:0005524 (20.1%) GO:0002161 (19.5%)" valyl-tRNA aminoacylation (20.1%) cytosol (20.1%) "valine-tRNA ligase activity (20.1%) ATP binding (20.1%) aminoacyl-tRNA deacylase activity (19.5%)" "IPR002300 (9.2%) IPR002303 (9.2%) IPR001412 (9.1%)" "Aminoacyl-tRNA synthetase, class Ia (9.2%) Valine-tRNA ligase (9.2%) Aminoacyl-tRNA synthetase, class I, conserved site (9.1%)" ASYGLVGNANLNGNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" FLGGHGSSLGGVLVDGGK Bacteria Bacteria "2.5.1.49 (66.7%) 4.4.1.11 (33.3%)" "O-acetylhomoserine aminocarboxypropyltransferase (66.7%) methionine gamma-lyase (33.3%)" "GO:0006535 (14.2%) GO:0019346 (14.2%) GO:0071269 (14.2%)" GO:0005737 (14.2%) "GO:0003961 (14.2%) GO:0004124 (14.2%) GO:0030170 (14.2%)" "cysteine biosynthetic process from serine (14.2%) transsulfuration (14.2%) L-homocysteine biosynthetic process (14.2%)" cytoplasm (14.2%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.2%) cysteine synthase activity (14.2%) pyridoxal phosphate binding (14.2%)" "IPR000277 (16.9%) IPR006235 (16.9%) IPR054542 (16.9%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (16.9%) O-acetylhomoserine/O-acetylserine sulfhydrylase (16.9%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (16.9%)" KYDLTGTELDAEADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (17.4%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (17.4%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (17.6%) IPR056740 (17.6%) IPR004404 (16.5%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.6%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.6%) Dihydroxy-acid dehydratase (16.5%)" REMLTPWSTNAVELTQNMSLDGLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.7%) IPR010918 (11.7%) IPR040707 (11.7%)" "Phosphoribosylformylglycinamidine synthase PurL (11.7%) PurM-like, C-terminal domain (11.7%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.7%)" EGKASDEELLTSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.6%) GO:0006396 (13.6%)" GO:0005829 (14.6%) "GO:0000175 (14.6%) GO:0003723 (14.6%) GO:0004654 (14.6%)" "mRNA catabolic process (14.6%) RNA processing (13.6%)" cytosol (14.6%) "3'-5'-RNA exonuclease activity (14.6%) RNA binding (14.6%) polyribonucleotide nucleotidyltransferase activity (14.6%)" "IPR001247 (8.1%) IPR012162 (8.1%) IPR015847 (8.1%)" "Exoribonuclease, phosphorolytic domain 1 (8.1%) Polyribonucleotide nucleotidyltransferase (8.1%) Exoribonuclease, phosphorolytic domain 2 (8.1%)" KTTDLLATVALAGGTNFGDQLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" YKGSLTQSPGLLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016829 (70%) GO:0004557 (30%)" "lyase activity (70%) alpha-galactosidase activity (30%)" "IPR052063 (36.8%) IPR011050 (31.6%) IPR012334 (31.6%)" "Polysaccharide Lyase 1 (36.8%) Pectin lyase fold/virulence factor (31.6%) Pectin lyase fold (31.6%)" WDEVGAEYVVESTGLFLAYDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (19.4%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (19.4%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" LLTYGKDENCDVWGEVLSCAPFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.2.10 (100%) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (100%) "GO:0008360 (14%) GO:0009252 (14%) GO:0051301 (14%)" GO:0005737 (14%) "GO:0005524 (14%) GO:0047480 (14%) GO:0008766 (2.2%)" "regulation of cell shape (14%) peptidoglycan biosynthetic process (14%) cell division (14%)" cytoplasm (14%) "ATP binding (14%) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity (14%) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity (2.2%)" "IPR000713 (12.7%) IPR004101 (12.7%) IPR005863 (12.7%)" "Mur ligase, N-terminal catalytic domain (12.7%) Mur ligase, C-terminal (12.7%) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (12.7%)" QAFLDKYGDGVEDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR000565 (7.7%) IPR001241 (7.7%) IPR002288 (7.7%)" "DNA topoisomerase, type IIA, subunit B (7.7%) DNA topoisomerase, type IIA (7.7%) DNA gyrase B subunit, C-terminal (7.7%)" ALLETLFSCGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006313 (16.7%) GO:0007059 (16.7%) GO:0051301 (16.7%)" GO:0005737 (16.7%) "GO:0003677 (16.7%) GO:0009037 (16.7%)" "DNA transposition (16.7%) chromosome segregation (16.7%) cell division (16.7%)" cytoplasm (16.7%) "DNA binding (16.7%) tyrosine-based site-specific recombinase activity (16.7%)" "IPR002104 (12.6%) IPR004107 (12.6%) IPR023009 (12.6%)" "Integrase, catalytic domain (12.6%) Integrase, SAM-like, N-terminal (12.6%) Tyrosine recombinase XerC/XerD (12.6%)" LLNYNSTSWFFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella LNVTFDVYQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.2%) IPR023996 (15.2%) IPR023997 (15.2%)" "TonB-dependent receptor, plug domain (15.2%) TonB-dependent outer membrane protein, SusC/RagA (15.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.2%)" KTDDGDYLLSAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (51.1%) GO:0050660 (48.9%) plasma membrane (51.1%) flavin adenine dinucleotide binding (48.9%) "IPR000644 (14.8%) IPR005170 (14.8%) IPR016169 (14.2%)" "CBS domain (14.8%) Transporter-associated domain (14.8%) FAD-binding, type PCMH, subdomain 2 (14.2%)" YHAHDENNEANVGDTVMLMETRPLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000266 (25%) IPR012340 (25%) IPR019979 (25%)" "Small ribosomal subunit protein uS17 (25%) Nucleic acid-binding, OB-fold (25%) Small ribosomal subunit protein uS17, conserved site (25%)" LDMSQAGAEPESVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR012547 (50%) IPR018631 (50%)" "PD-(D/E)XK nuclease superfamily 9 (50%) AAA-ATPase-like domain (50%)" LGDTSWLKPGK Pseudomonadati Bacteria Pseudomonadati "3.2.1.- (50%) 3.2.1.20 (50%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (50%) alpha-glucosidase (50%)" "GO:0030246 (50%) GO:0016798 (46.9%) GO:0004558 (1.6%)" "carbohydrate binding (50%) hydrolase activity, acting on glycosyl bonds (46.9%) alpha-1,4-glucosidase activity (1.6%)" "IPR019563 (13%) IPR052720 (13%) IPR013785 (12.6%)" "Glycosyl-hydrolase 97, catalytic domain (13%) Glycosyl Hydrolase Family 97 (13%) Aldolase-type TIM barrel (12.6%)" ATSAETYAQLEQDFKDALADLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" AHSDLYNLLLQVMDYAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0034605 (23.9%) GO:0006508 (2.2%)" GO:0005737 (23.9%) "GO:0005524 (23.9%) GO:0016887 (23.9%) GO:0008233 (2.2%)" "cellular response to heat (23.9%) proteolysis (2.2%)" cytoplasm (23.9%) "ATP binding (23.9%) ATP hydrolysis activity (23.9%) peptidase activity (2.2%)" "IPR003959 (10.4%) IPR019489 (10.4%) IPR050130 (10.4%)" "ATPase, AAA-type, core (10.4%) Clp ATPase, C-terminal (10.4%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (10.4%)" FFYLDYTEDYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (49%) GO:0016787 (51%) membrane (49%) hydrolase activity (51%) "IPR005079 (33.8%) IPR052193 (33.8%) IPR029055 (32.4%)" "Peptidase C45, hydrolase domain (33.8%) Peptidase C59 family enzymes (33.8%) Nucleophile aminohydrolases, N-terminal (32.4%)" NYQCSGCPFVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) VLSVEADRDHANFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.1.171 (100%) 16S rRNA (guanine(966)-N(2))-methyltransferase (100%) GO:0031167 (31.9%) "GO:0003676 (34%) GO:0008168 (31.9%) GO:0052913 (2.1%)" rRNA methylation (31.9%) "nucleic acid binding (34%) methyltransferase activity (31.9%) 16S rRNA (guanine(966)-N(2))-methyltransferase activity (2.1%)" "IPR002052 (34%) IPR004398 (34%) IPR029063 (31.9%)" "DNA methylase, N-6 adenine-specific, conserved site (34%) RNA methyltransferase, RsmD (34%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (31.9%)" TGVNMKPETTCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25%) IPR005263 (25%) IPR013785 (25%)" "DapA-like (25%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25%) Aldolase-type TIM barrel (25%)" YASYWLQHVWVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (25%) IPR024361 (25%) IPR032339 (25%)" "Immunoglobulin-like fold (25%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (25%) Domain of unknown function DUF4859 (25%)" LDFSNLFAQDQQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) IPR014942 (100%) Nucleotidyl transferase AbiEii toxin, Type IV TA system (100%) KVAAEAASVPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FMLFANANNTSDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR041700 (87%) IPR008969 (13%)" "Outer membrane protein beta-barrel domain 3 (87%) Carboxypeptidase-like, regulatory domain superfamily (13%)" LRDLTNLEAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019346 (20.4%) GO:0005737 (20.4%) "GO:0016846 (20.4%) GO:0030170 (20.4%) GO:0016740 (12.2%)" transsulfuration (20.4%) cytoplasm (20.4%) "carbon-sulfur lyase activity (20.4%) pyridoxal phosphate binding (20.4%) transferase activity (12.2%)" "IPR000277 (25.6%) IPR015421 (25.6%) IPR015424 (25.6%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (25.6%) Pyridoxal phosphate-dependent transferase, major domain (25.6%) Pyridoxal phosphate-dependent transferase (25.6%)" KEGLNVELDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (12.1%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (12.1%)" "IPR015939 (14.4%) IPR030664 (14.4%) IPR037099 (14.4%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (14.4%)" GMEAADDYVVTLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) "IPR003961 (23.8%) IPR008757 (23.8%) IPR013783 (19%)" "Fibronectin type III (23.8%) Peptidase M6-like, domain (23.8%) Immunoglobulin-like fold (19%)" EQADNQLLGDAFQHLLDTYLSSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015969 (44.2%) GO:0005886 (44.2%) GO:0016787 (11.5%) guanosine tetraphosphate metabolic process (44.2%) plasma membrane (44.2%) hydrolase activity (11.5%) "IPR002912 (9.2%) IPR003607 (9.2%) IPR004095 (9.2%)" "ACT domain (9.2%) HD/PDEase domain (9.2%) TGS (9.2%)" DTGLLDLLLPELVAMDKVETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0042245 (17.2%) GO:0008033 (15.7%) GO:0006396 (1.5%)" "GO:0003723 (17.2%) GO:0016779 (17.2%) GO:0000166 (15.7%)" "RNA repair (17.2%) tRNA processing (15.7%) RNA processing (1.5%)" "RNA binding (17.2%) nucleotidyltransferase activity (17.2%) nucleotide binding (15.7%)" "IPR003607 (14.6%) IPR006674 (14.6%) IPR006675 (14.6%)" "HD/PDEase domain (14.6%) HD domain (14.6%) HDIG domain (14.6%)" LDKPQFNWGYDPK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50.6%) "GO:0016798 (32.5%) GO:0051060 (14.3%) GO:0004553 (2.6%)" carbohydrate metabolic process (50.6%) "hydrolase activity, acting on glycosyl bonds (32.5%) pullulanase activity (14.3%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.6%)" "IPR006047 (14.9%) IPR011840 (14.5%) IPR049117 (14.5%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Pullulanase, type I (14.5%) Pullulanase, all-beta domain (14.5%)" NYLESTASSMFAYVLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (43%) "GO:0004650 (43%) GO:0004557 (13.9%)" carbohydrate metabolic process (43%) "polygalacturonase activity (43%) alpha-galactosidase activity (13.9%)" "IPR000743 (12.9%) IPR006626 (12.9%) IPR010905 (12.9%)" "Glycoside hydrolase, family 28 (12.9%) Parallel beta-helix repeat (12.9%) Glycosyl hydrolase, family 88 (12.9%)" DKVNMLELNTTPGMTVTSFLPQQVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.7%) GO:0008360 (12.6%) GO:0009252 (12.6%)" GO:0005737 (12.6%) "GO:0005524 (15.8%) GO:0008716 (15.8%) GO:0046872 (15.8%)" "cell wall organization (14.7%) regulation of cell shape (12.6%) peptidoglycan biosynthetic process (12.6%)" cytoplasm (12.6%) "ATP binding (15.8%) D-alanine-D-alanine ligase activity (15.8%) metal ion binding (15.8%)" "IPR011095 (15.3%) IPR011761 (15.3%) IPR000291 (14.3%)" "D-alanine--D-alanine ligase, C-terminal (15.3%) ATP-grasp fold (15.3%) D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.3%)" GAFYGMQSFMQLLPAQLESATR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (26%) GO:0030203 (24%)" GO:0016020 (24%) "GO:0004563 (24%) GO:0016798 (2.1%)" "carbohydrate metabolic process (26%) glycosaminoglycan metabolic process (24%)" membrane (24%) "beta-N-acetylhexosaminidase activity (24%) hydrolase activity, acting on glycosyl bonds (2.1%)" "IPR015882 (17.5%) IPR011658 (16.8%) IPR015883 (16.8%)" "Beta-hexosaminidase, bacterial type, N-terminal (17.5%) PA14 domain (16.8%) Glycoside hydrolase family 20, catalytic domain (16.8%)" RVVVTGLGAVTPVGNTPEETWESLLAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.5%) IPR014030 (14.5%) IPR014031 (14.5%)" "Beta-ketoacyl synthase (14.5%) Beta-ketoacyl synthase-like, N-terminal (14.5%) Beta-ketoacyl synthase, C-terminal (14.5%)" VQPGSELVLPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" DLVNWQPAGHVLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20%) IPR013320 (20%) IPR023296 (20%)" "Glycoside hydrolase, family 43 (20%) Concanavalin A-like lectin/glucanase domain superfamily (20%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (20%)" CEPGLVTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" SEEFVADGLGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.33 (100%) pantothenate kinase (100%) GO:0015937 (25%) GO:0005829 (25%) "GO:0004594 (25%) GO:0005524 (25%)" coenzyme A biosynthetic process (25%) cytosol (25%) "pantothenate kinase activity (25%) ATP binding (25%)" "IPR004567 (50%) IPR043129 (50%)" "Type II pantothenate kinase (50%) ATPase, nucleotide binding domain (50%)" LFWPLETLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (52.8%) GO:0050660 (47.2%) plasma membrane (52.8%) flavin adenine dinucleotide binding (47.2%) "IPR002550 (13.1%) IPR000644 (12.8%) IPR005170 (12.8%)" "CNNM, transmembrane domain (13.1%) CBS domain (12.8%) Transporter-associated domain (12.8%)" KGNFTFGLR Bacteria Bacteria "IPR018392 (34.6%) IPR028082 (32.7%) IPR036779 (32.7%)" "LysM domain (34.6%) Periplasmic binding protein-like I (32.7%) LysM domain superfamily (32.7%)" YTLNDEGVFTFDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LENSDTDAKGTLSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) DFAQFHPGGELGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.13 (100%) arabinose-5-phosphate isomerase (100%) "GO:0005975 (25%) GO:1901135 (25%)" "GO:0019146 (25%) GO:0097367 (25%)" "carbohydrate metabolic process (25%) carbohydrate derivative metabolic process (25%)" "arabinose-5-phosphate isomerase activity (25%) carbohydrate derivative binding (25%)" "IPR000644 (14.4%) IPR001347 (14.4%) IPR004800 (14.4%)" "CBS domain (14.4%) SIS domain (14.4%) Phosphosugar isomerase, KdsD/KpsF-type (14.4%)" LNNTLGQLLMAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "4.2.1.20 (86.3%) 5.3.1.24 (13.7%)" "tryptophan synthase (86.3%) phosphoribosylanthranilate isomerase (13.7%)" GO:0005737 (45.1%) "GO:0004834 (45.1%) GO:0004640 (9.9%)" cytoplasm (45.1%) "tryptophan synthase activity (45.1%) phosphoribosylanthranilate isomerase activity (9.9%)" "IPR001926 (17.7%) IPR006653 (17.7%) IPR023026 (17.7%)" "Tryptophan synthase beta chain-like, PALP domain (17.7%) Tryptophan synthase, beta chain, conserved site (17.7%) Tryptophan synthase beta chain/beta chain-like (17.7%)" YEYQTEEGEGRFEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (50.6%) IPR023614 (49.4%)" "Phosphate-selective porin O/P (50.6%) Porin domain superfamily (49.4%)" YNYSGYSALNTALDEALAALESAKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" LLVTSLLR root "3.5.1.2 (36%) 6.2.1.44 (18%) 2.7.13.3 (10%)" "glutaminase (36%) 3-(methylthio)propionyl--CoA ligase (18%) histidine kinase (10%)" "GO:0006537 (2.8%) GO:0006543 (2.8%) GO:0006629 (2.7%)" "GO:0016020 (18.8%) GO:0005886 (3%) GO:0005634 (2%)" "GO:0004359 (2.8%) GO:0008374 (2.5%) GO:0005524 (2%)" "glutamate biosynthetic process (2.8%) L-glutamine catabolic process (2.8%) lipid metabolic process (2.7%)" "membrane (18.8%) plasma membrane (3%) nucleus (2%)" "glutaminase activity (2.8%) O-acyltransferase activity (2.5%) ATP binding (2%)" "IPR043769 (5.3%) IPR009045 (4.1%) IPR027417 (3%)" "Protein of unknown function DUF5715 (5.3%) Peptidase M74/Hedgehog-like, zinc-binding domain superfamily (4.1%) P-loop containing nucleoside triphosphate hydrolase (3%)" VEANLNLGASYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" QVTMYLAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006270 (14.3%) GO:0006275 (14.3%)" "GO:0005737 (14.3%) GO:0005886 (14.3%)" "GO:0003688 (14.3%) GO:0005524 (14.3%) GO:0008289 (14.3%)" "DNA replication initiation (14.3%) regulation of DNA replication (14.3%)" "cytoplasm (14.3%) plasma membrane (14.3%)" "DNA replication origin binding (14.3%) ATP binding (14.3%) lipid binding (14.3%)" "IPR001957 (10.3%) IPR003593 (10.3%) IPR013159 (10.3%)" "Chromosomal replication control, initiator DnaA (10.3%) AAA+ ATPase domain (10.3%) Chromosomal replication initiator, DnaA C-terminal (10.3%)" DKGFTLVTYAYGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR012505 (50%) IPR053154 (50%)" "YbbR-like (50%) Cyclic di-AMP regulator (50%)" QAAQSTLAAVYMSMAGYPLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.7%) IPR012944 (33.3%) IPR011990 (31%)" "SusD-like, N-terminal (35.7%) RagB/SusD domain (33.3%) Tetratricopeptide-like helical domain superfamily (31%)" TPLTLLLTPLFTLLKEDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (0.7%) "GO:0000155 (24.8%) GO:0003700 (24.8%) GO:0005524 (24.8%)" membrane (0.7%) "phosphorelay sensor kinase activity (24.8%) DNA-binding transcription factor activity (24.8%) ATP binding (24.8%)" "IPR001789 (7.3%) IPR003594 (7.3%) IPR003661 (7.3%)" "Signal transduction response regulator, receiver domain (7.3%) Histidine kinase/HSP90-like ATPase domain (7.3%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.3%)" LTLNLPMLAGK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0016798 (49.3%) GO:0030246 (47.9%) GO:0016787 (2.8%)" "hydrolase activity, acting on glycosyl bonds (49.3%) carbohydrate binding (47.9%) hydrolase activity (2.8%)" "IPR029483 (13.1%) IPR052720 (13.1%) IPR019563 (12.7%)" "Glycosyl-hydrolase 97, C-terminal oligomerisation domain (13.1%) Glycosyl Hydrolase Family 97 (13.1%) Glycosyl-hydrolase 97, catalytic domain (12.7%)" ADEGTNNSLSPTFLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR011990 (33.3%) IPR018704 (33.3%) IPR019734 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) Ancillary SecYEG translocon subunit/Cell division coordinator CpoB, TPR domain (33.3%) Tetratricopeptide repeat (33.3%)" ELGYVYVDTGAMYR Bacteria Bacteria 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (18.3%) GO:0015949 (17.6%)" "GO:0005829 (17.6%) GO:0005737 (0.7%)" "GO:0005524 (18.3%) GO:0036431 (18.3%) GO:0036430 (9.2%)" "pyrimidine nucleotide metabolic process (18.3%) nucleobase-containing small molecule interconversion (17.6%)" "cytosol (17.6%) cytoplasm (0.7%)" "ATP binding (18.3%) dCMP kinase activity (18.3%) CMP kinase activity (9.2%)" "IPR003136 (33.3%) IPR011994 (33.3%) IPR027417 (33.3%)" "Cytidylate kinase (33.3%) Cytidylate kinase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" GDKDVETYLSHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (50%) GO:0004834 (50%) cytoplasm (50%) tryptophan synthase activity (50%) "IPR001926 (20%) IPR006653 (20%) IPR006654 (20%)" "Tryptophan synthase beta chain-like, PALP domain (20%) Tryptophan synthase, beta chain, conserved site (20%) Tryptophan synthase, beta chain (20%)" LLTTAEDVMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.13 (100%) arabinose-5-phosphate isomerase (100%) "GO:0005975 (25%) GO:1901135 (25%)" "GO:0019146 (25%) GO:0097367 (25%)" "carbohydrate metabolic process (25%) carbohydrate derivative metabolic process (25%)" "arabinose-5-phosphate isomerase activity (25%) carbohydrate derivative binding (25%)" "IPR000644 (14.4%) IPR001347 (14.4%) IPR004800 (14.4%)" "CBS domain (14.4%) SIS domain (14.4%) Phosphosugar isomerase, KdsD/KpsF-type (14.4%)" FTTEMDLSLNQLLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005615 (50%) GO:0004867 (50%) extracellular space (50%) serine-type endopeptidase inhibitor activity (50%) "IPR000215 (17.2%) IPR023795 (17.2%) IPR023796 (17.2%)" "Serpin family (17.2%) Serpin, conserved site (17.2%) Serpin domain (17.2%)" VTELLEAR root "2.7.7.6 (66.7%) 2.7.13.3 (6.7%) 1.18.1.2 (3.3%)" "DNA-directed RNA polymerase (66.7%) histidine kinase (6.7%) ferredoxin--NADP(+) reductase (3.3%)" "GO:0006351 (7.9%) GO:0005975 (1.2%) GO:0007155 (1.2%)" "GO:0000428 (7.9%) GO:0005576 (1.7%) GO:0005737 (1.7%)" "GO:0003677 (9.5%) GO:0008270 (8.7%) GO:0000287 (7.9%)" "DNA-templated transcription (7.9%) carbohydrate metabolic process (1.2%) cell adhesion (1.2%)" "DNA-directed RNA polymerase complex (7.9%) extracellular region (1.7%) cytoplasm (1.7%)" "DNA binding (9.5%) zinc ion binding (8.7%) magnesium ion binding (7.9%)" "IPR000722 (4.9%) IPR006592 (4.9%) IPR007066 (4.9%)" "RNA polymerase, alpha subunit (4.9%) RNA polymerase, N-terminal (4.9%) RNA polymerase Rpb1, domain 3 (4.9%)" NDLDSELWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (34.4%) IPR015854 (34.4%) IPR027417 (31.3%)" "ABC transporter-like, ATP-binding domain (34.4%) ABC transporter, lipoprotein release, LolD-like (34.4%) P-loop containing nucleoside triphosphate hydrolase (31.3%)" FPTLLAYAYNLYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.16 (100%) citrate synthase (unknown stereospecificity) (100%) "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (15.7%) GO:0046912 (9.3%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (15.7%) acyltransferase activity, acyl groups converted into alkyl on transfer (9.3%)" "IPR002020 (20.6%) IPR016142 (20.2%) IPR036969 (20.2%)" "Citrate synthase (20.6%) Citrate synthase-like, large alpha subdomain (20.2%) Citrate synthase superfamily (20.2%)" YPGADPETASLNSGASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.1%) IPR012910 (14.1%) IPR023996 (14.1%)" "Carboxypeptidase-like, regulatory domain superfamily (14.1%) TonB-dependent receptor, plug domain (14.1%) TonB-dependent outer membrane protein, SusC/RagA (14.1%)" ETFAEVTK Bacteria Bacteria 3.2.1.4 (100%) cellulase (100%) GO:0030245 (4.5%) GO:0016020 (86.4%) "GO:0008810 (4.5%) GO:0030248 (4.5%)" cellulose catabolic process (4.5%) membrane (86.4%) "cellulase activity (4.5%) cellulose binding (4.5%)" "IPR007156 (40%) IPR023353 (40%) IPR001701 (2.2%)" "MamQ/LemA (40%) LemA-like domain superfamily (40%) Glycoside hydrolase family 9 (2.2%)" FLLHDLNKAEAYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLLSTLFNALGCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR012547 (50%) IPR018631 (50%)" "PD-(D/E)XK nuclease superfamily 9 (50%) AAA-ATPase-like domain (50%)" ALAAYTEVLNELEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.8%) IPR011990 (47.2%)" "Tetratricopeptide repeat (52.8%) Tetratricopeptide-like helical domain superfamily (47.2%)" KCNLNTLDQDLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.6%) GO:0006221 (13.5%) GO:0006526 (12.5%)" GO:0005737 (14.6%) "GO:0004088 (14.6%) GO:0005524 (14.6%) GO:0046872 (14.6%)" "glutamine metabolic process (14.6%) pyrimidine nucleotide biosynthetic process (13.5%) L-arginine biosynthetic process (12.5%)" cytoplasm (14.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.6%) ATP binding (14.6%) metal ion binding (14.6%)" "IPR005480 (11.8%) IPR005479 (10.9%) IPR011761 (10.9%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (11.8%) Carbamoyl phosphate synthase, ATP-binding domain (10.9%) ATP-grasp fold (10.9%)" NDDRYLLAGYPWFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.3%) IPR024742 (20.3%) IPR032790 (20.3%)" "Glycogen debranching enzyme (20.3%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.3%) Glycogen debranching enzyme, C-terminal (20.3%)" LEAGLQDWTWTGSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" NLGTFFTDVENSFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.48 (100%) indole-3-glycerol-phosphate synthase (100%) "GO:0000162 (32.9%) GO:0006568 (0.4%)" "GO:0004425 (32.9%) GO:0004640 (32.9%) GO:0016757 (0.4%)" "L-tryptophan biosynthetic process (32.9%) L-tryptophan metabolic process (0.4%)" "indole-3-glycerol-phosphate synthase activity (32.9%) phosphoribosylanthranilate isomerase activity (32.9%) glycosyltransferase activity (0.4%)" "IPR013798 (20.2%) IPR045186 (20.2%) IPR001468 (20%)" "Indole-3-glycerol phosphate synthase domain (20.2%) Indole-3-glycerol phosphate synthase (20.2%) Indole-3-glycerol phosphate synthase, conserved site (20%)" RWNLNSLEFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.4.1.13 (50%) 1.4.1.14 (50%)" "glutamate synthase (NADPH) (50%) glutamate synthase (NADH) (50%)" GO:0006537 (32.7%) "GO:0016639 (32.7%) GO:0051536 (32.7%) GO:0004355 (0.9%)" glutamate biosynthetic process (32.7%) "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (32.7%) iron-sulfur cluster binding (32.7%) glutamate synthase (NADPH) activity (0.9%)" "IPR006005 (16.7%) IPR009051 (16.7%) IPR023753 (16.7%)" "Glutamate synthase, NADH/NADPH, small subunit 1 (16.7%) Alpha-helical ferredoxin (16.7%) FAD/NAD(P)-binding domain (16.7%)" VALAPQYEYSHFQYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) LYLDKTEYLYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005524 (100%) ATP binding (100%) "IPR018631 (41%) IPR027417 (30.5%) IPR012547 (28.6%)" "AAA-ATPase-like domain (41%) P-loop containing nucleoside triphosphate hydrolase (30.5%) PD-(D/E)XK nuclease superfamily 9 (28.6%)" DEAENLKK root 4.2.1.1 (100%) carbonic anhydrase (100%) "GO:0006412 (20.5%) GO:0015074 (1.3%) GO:0016055 (0.7%)" "GO:0022625 (18.5%) GO:0005762 (2%) GO:0016020 (1.3%)" "GO:0003729 (20.5%) GO:0003735 (20.5%) GO:0003677 (1.3%)" "translation (20.5%) DNA integration (1.3%) Wnt signaling pathway (0.7%)" "cytosolic large ribosomal subunit (18.5%) mitochondrial large ribosomal subunit (2%) membrane (1.3%)" "mRNA binding (20.5%) structural constituent of ribosome (20.5%) DNA binding (1.3%)" "IPR000206 (16.8%) IPR013823 (16.8%) IPR014719 (16.8%)" "Large ribosomal subunit protein bL12 (16.8%) Large ribosomal subunit protein bL12, C-terminal (16.8%) Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like (16.8%)" SNLEHPNLLTESGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (20%) GO:0008295 (20%) GO:0033388 (20%)" "GO:0008792 (20%) GO:0046872 (20%)" "L-arginine catabolic process (20%) spermidine biosynthetic process (20%) putrescine biosynthetic process from arginine (20%)" "arginine decarboxylase activity (20%) metal ion binding (20%)" "IPR000183 (11.1%) IPR002985 (11.1%) IPR009006 (11.1%)" "Ornithine/DAP/Arg decarboxylase (11.1%) Arginine decarboxylase (11.1%) Alanine racemase/group IV decarboxylase, C-terminal (11.1%)" LWGYTTYK Bacteria Bacteria "IPR021428 (87.5%) IPR014951 (12.5%)" "Protein of unknown function DUF3078 (87.5%) Protein of unknown function DUF1822 (12.5%)" LPLDDLLFVDCDKDYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000156 (50%) GO:0003677 (50%)" "phosphorelay response regulator activity (50%) DNA binding (50%)" "IPR001789 (25.6%) IPR007492 (25.6%) IPR046947 (25.6%)" "Signal transduction response regulator, receiver domain (25.6%) LytTR DNA-binding domain (25.6%) Transcriptional regulatory protein LytR-like (25.6%)" TSNSAMYFESAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (23.1%) IPR057601 (23.1%) IPR008969 (17.9%)" "TonB-dependent receptor-like (23.1%) TonB-dependent transporter Oar-like, beta-barrel domain (23.1%) Carboxypeptidase-like, regulatory domain superfamily (17.9%)" VPAPVGDEKAPLQALLFDSVFNSFR Pseudomonadati Bacteria Pseudomonadati 3.6.5.0 (100%) Unknown (100%) GO:0045727 (17.3%) GO:0005886 (15.4%) "GO:0003924 (17.3%) GO:0005525 (17.3%) GO:0043022 (17.3%)" positive regulation of translation (17.3%) plasma membrane (15.4%) "GTPase activity (17.3%) GTP binding (17.3%) ribosome binding (17.3%)" "IPR000795 (10.6%) IPR005225 (10.6%) IPR006297 (10.6%)" "Translational (tr)-type GTP-binding domain (10.6%) Small GTP-binding domain (10.6%) Elongation factor 4 (10.6%)" LHLGHYLGSLQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" NVTDDNDLMLLNQSGLVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.9%) IPR005743 (12.9%) IPR006691 (12.9%)" "DNA topoisomerase, type IIA, domain A (12.9%) DNA gyrase, subunit A (12.9%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.9%)" NTTAEAVELGFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" GNDWYVGGQSNWDER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016798 (47.9%) GO:0030246 (47.9%) GO:0016787 (4.2%)" "hydrolase activity, acting on glycosyl bonds (47.9%) carbohydrate binding (47.9%) hydrolase activity (4.2%)" "IPR019563 (13.2%) IPR029483 (13.2%) IPR052720 (13.2%)" "Glycosyl-hydrolase 97, catalytic domain (13.2%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (13.2%) Glycosyl Hydrolase Family 97 (13.2%)" DENVMLVSGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.9%) GO:0005737 (48.9%)" GO:0016787 (2.2%) "extracellular region (48.9%) cytoplasm (48.9%)" hydrolase activity (2.2%) "IPR006530 (16.5%) IPR050708 (16.5%) IPR031325 (16.1%)" "YD repeat (16.5%) Type VI secretion system VgrG/RHS (16.5%) RHS repeat (16.1%)" SPVWMNK root "GO:0005886 (43.8%) GO:0019867 (6.3%)" "GO:0008519 (43.8%) GO:2001070 (6.3%)" "plasma membrane (43.8%) outer membrane (6.3%)" "ammonium channel activity (43.8%) starch binding (6.3%)" "IPR001905 (22.6%) IPR024041 (22.6%) IPR029020 (19.4%)" "Ammonium transporter (22.6%) Ammonium transporter AmtB-like domain (22.6%) Ammonium/urea transporter (19.4%)" DLFDKELLDAYLADFPLGDTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (25%) "GO:0005737 (25%) GO:0005840 (25%)" GO:0008276 (25%) methylation (25%) "cytoplasm (25%) ribosome (25%)" protein methyltransferase activity (25%) "IPR004498 (33.3%) IPR029063 (33.3%) IPR050078 (33.3%)" "Ribosomal protein L11 methyltransferase (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%) Ribosomal protein L11 methyltransferase PrmA (33.3%)" TYHTTEQFLNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YQVYTDR root "3.1.1.- (50%) 3.1.3.- (50%)" "Carboxylic ester hydrolases (50%) Phosphoric monoester hydrolases (50%)" "GO:0006260 (4.8%) GO:0007157 (1.6%) GO:0007160 (1.6%)" "GO:0005829 (8.1%) GO:0008305 (1.6%) GO:0009897 (1.6%)" "GO:0004866 (48.4%) GO:0000287 (8.1%) GO:0016791 (8.1%)" "DNA replication (4.8%) heterophilic cell-cell adhesion (1.6%) cell-matrix adhesion (1.6%)" "cytosol (8.1%) integrin complex (1.6%) external side of plasma membrane (1.6%)" "endopeptidase inhibitor activity (48.4%) magnesium ion binding (8.1%) phosphatase activity (8.1%)" "IPR002890 (14.8%) IPR051802 (14.8%) IPR001599 (14.3%)" "Macroglobulin domain (14.8%) Alpha-2-macroglobulin-like (14.8%) Alpha-2-macroglobulin (14.3%)" LHYEPVGEPVDMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009055 (25%) GO:0010181 (25%) GO:0016491 (25%)" "electron transfer activity (25%) FMN binding (25%) oxidoreductase activity (25%)" "IPR029039 (17.5%) IPR001279 (16.5%) IPR008254 (16.5%)" "Flavoprotein-like superfamily (17.5%) Metallo-beta-lactamase (16.5%) Flavodoxin/nitric oxide synthase (16.5%)" LTDGETLTQTLSVLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (25%) GO:0003700 (25%) GO:0005524 (25%)" "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) ATP binding (25%)" "IPR001789 (6.7%) IPR003594 (6.7%) IPR003661 (6.7%)" "Signal transduction response regulator, receiver domain (6.7%) Histidine kinase/HSP90-like ATPase domain (6.7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.7%)" LFGFENYEAQLSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" AEKGEAYLSFVVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (52.2%) IPR036737 (47.8%)" "Domain of unknown function DUF3868 (52.2%) OmpA-like domain superfamily (47.8%)" EALELMLR root "1.-.-.- (20.8%) 2.7.13.3 (20.8%) 1.14.13.- (12.5%)" "Oxidoreductases (20.8%) histidine kinase (20.8%) With NADH or NADPH as one donor, and incorporation of one atom of oxygen (12.5%)" "GO:0000082 (2.4%) GO:0070534 (2.4%) GO:1905168 (2.4%)" "GO:0005737 (4.9%) GO:0005634 (2.4%) GO:0019005 (2.4%)" "GO:0016705 (20%) GO:0004497 (14.7%) GO:0005524 (5.3%)" "G1/S transition of mitotic cell cycle (2.4%) protein K63-linked ubiquitination (2.4%) positive regulation of double-strand break repair via homologous recombination (2.4%)" "cytoplasm (4.9%) nucleus (2.4%) SCF ubiquitin ligase complex (2.4%)" "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (20%) monooxygenase activity (14.7%) ATP binding (5.3%)" "IPR011251 (14.6%) IPR036661 (14.6%) IPR051260 (14%)" "Luciferase-like domain (14.6%) Luciferase-like domain superfamily (14.6%) Diverse substrate monooxygenases (14%)" YSDEFDRVEGADFYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36%) IPR011990 (32%) IPR033985 (32%)" "RagB/SusD domain (36%) Tetratricopeptide-like helical domain superfamily (32%) SusD-like, N-terminal (32%)" EDLCGCGNLLEQDNTPLADLDRTPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" FDEYNLSYAAEMSDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR032252 (52.5%) IPR046357 (47.5%)" "Protein of unknown function DUF4827 (52.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (47.5%)" SGAFDEVLDFDELTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016788 (93.1%) GO:0016787 (6.9%)" "hydrolase activity, acting on ester bonds (93.1%) hydrolase activity (6.9%)" "IPR013830 (34.1%) IPR053140 (34.1%) IPR036514 (31.8%)" "SGNH hydrolase-type esterase domain (34.1%) GDSL lipase Rv0518-like (34.1%) SGNH hydrolase superfamily (31.8%)" YSLSVSMR Bacteria Bacteria "GO:0009307 (2.6%) GO:0044718 (2.6%)" GO:0009279 (89.7%) "GO:0003677 (2.6%) GO:0015344 (2.6%)" "DNA restriction-modification system (2.6%) siderophore transmembrane transport (2.6%)" cell outer membrane (89.7%) "DNA binding (2.6%) siderophore uptake transmembrane transporter activity (2.6%)" "IPR039426 (14.8%) IPR012910 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor-like (14.8%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" MAEDGVPFDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (44.4%) "GO:0004650 (44.4%) GO:0004557 (11.1%)" carbohydrate metabolic process (44.4%) "polygalacturonase activity (44.4%) alpha-galactosidase activity (11.1%)" "IPR000743 (13%) IPR006626 (13%) IPR010905 (13%)" "Glycoside hydrolase, family 28 (13%) Parallel beta-helix repeat (13%) Glycosyl hydrolase, family 88 (13%)" NAGNVLNVMSQQSLQLSPDVNVASVLQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.3%) IPR012910 (20.3%) IPR008969 (19.8%)" "TonB-dependent receptor-like, beta-barrel (20.3%) TonB-dependent receptor, plug domain (20.3%) Carboxypeptidase-like, regulatory domain superfamily (19.8%)" FPPVEQR root "2.1.1.- (40%) 2.3.1.31 (40%) 2.3.1.30 (20%)" "Methyltransferases (40%) homoserine O-acetyltransferase (40%) serine O-acetyltransferase (20%)" "GO:0009100 (30%) GO:0006391 (3.3%) GO:0006355 (1.7%)" "GO:0005737 (5%) GO:0005634 (3.3%) GO:0005759 (3.3%)" "GO:0003677 (5%) GO:0000179 (3.3%) GO:0003723 (3.3%)" "glycoprotein metabolic process (30%) transcription initiation at mitochondrial promoter (3.3%) regulation of DNA-templated transcription (1.7%)" "cytoplasm (5%) nucleus (3.3%) mitochondrial matrix (3.3%)" "DNA binding (5%) rRNA (adenine-N6,N6-)-dimethyltransferase activity (3.3%) RNA binding (3.3%)" "IPR007074 (20.5%) IPR052942 (19.3%) IPR029063 (3.4%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (20.5%) Lipopolysaccharide cholinephosphotransferase (19.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (3.4%)" VVMLEADNKFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011260 (16.7%) IPR011262 (16.7%) IPR011263 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (16.7%) DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%)" SYGSVNFSLFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.1.1.171 (90.9%) 2.1.1.- (9.1%)" "16S rRNA (guanine(966)-N(2))-methyltransferase (90.9%) Methyltransferases (9.1%)" "GO:0031167 (32%) GO:0032259 (0.6%)" "GO:0003676 (33.7%) GO:0008168 (32.5%) GO:0052913 (1.2%)" "rRNA methylation (32%) methylation (0.6%)" "nucleic acid binding (33.7%) methyltransferase activity (32.5%) 16S rRNA (guanine(966)-N(2))-methyltransferase activity (1.2%)" "IPR002052 (33.9%) IPR004398 (33.3%) IPR029063 (32.7%)" "DNA methylase, N-6 adenine-specific, conserved site (33.9%) RNA methyltransferase, RsmD (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (32.7%)" GLSATDAGAALQGK Pseudomonadati Bacteria Pseudomonadati GO:0044718 (6.7%) GO:0009279 (86.7%) GO:0015344 (6.7%) siderophore transmembrane transport (6.7%) cell outer membrane (86.7%) siderophore uptake transmembrane transporter activity (6.7%) "IPR012910 (14.6%) IPR037066 (14.6%) IPR039426 (14.6%)" "TonB-dependent receptor, plug domain (14.6%) TonB-dependent receptor, plug domain superfamily (14.6%) TonB-dependent receptor-like (14.6%)" MALLNGAFYLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.4%) GO:0005886 (25.4%) "GO:0000286 (25.4%) GO:0000166 (23.7%)" L-alanine catabolic process (25.4%) plasma membrane (25.4%) "alanine dehydrogenase activity (25.4%) nucleotide binding (23.7%)" "IPR007698 (20%) IPR007886 (20%) IPR008141 (20%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20%) Alanine dehydrogenase (20%)" FTTSNPEDMTEDLLHALAEEPNLCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.8.4.3 (100%) tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (100%) GO:0005829 (25%) "GO:0035597 (25%) GO:0046872 (25%) GO:0051539 (25%)" cytosol (25%) "tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR002792 (13%) IPR006638 (13%) IPR007197 (13%)" "TRAM domain (13%) Elp3/MiaA/NifB-like, radical SAM core domain (13%) Radical SAM (13%)" TLVPEPVVTSLSNEFAKDGETVTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (30.4%) IPR014756 (28.3%) IPR040475 (28.3%)" "Immunoglobulin-like fold (30.4%) Immunoglobulin E-set (28.3%) Surface glycan-binding protein B, xyloglucan binding domain (28.3%)" VTVPSVSPEQGPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004560 (50%) carbohydrate metabolic process (50%) alpha-L-fucosidase activity (50%) "IPR008928 (16.7%) IPR012341 (16.7%) IPR016518 (16.7%)" "Six-hairpin glycosidase superfamily (16.7%) Six-hairpin glycosidase-like superfamily (16.7%) Alpha-L-fucosidase (16.7%)" SVGLSLAEHPNTTQFNPMFLYGPSGSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006270 (14.3%) GO:0006275 (14.3%)" "GO:0005737 (14.3%) GO:0005886 (14.3%)" "GO:0003688 (14.3%) GO:0005524 (14.3%) GO:0008289 (14.3%)" "DNA replication initiation (14.3%) regulation of DNA replication (14.3%)" "cytoplasm (14.3%) plasma membrane (14.3%)" "DNA replication origin binding (14.3%) ATP binding (14.3%) lipid binding (14.3%)" "IPR001957 (10.4%) IPR003593 (10.4%) IPR013159 (10.4%)" "Chromosomal replication control, initiator DnaA (10.4%) AAA+ ATPase domain (10.4%) Chromosomal replication initiator, DnaA C-terminal (10.4%)" SLYDANGDLLDTDWVDQMFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" LTATLTSPQTDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.3%) GO:0046556 (50.7%) L-arabinose metabolic process (49.3%) alpha-L-arabinofuranosidase activity (50.7%) "IPR003305 (17.1%) IPR051563 (17.1%) IPR010720 (16.6%)" "Carbohydrate-binding, CenC-like (17.1%) Glycosyl Hydrolase Family 51 (17.1%) Alpha-L-arabinofuranosidase, C-terminal (16.6%)" TDYDKLVLELTTDGSLSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (17.1%) IPR011263 (17.1%) IPR011773 (17.1%)" "DNA-directed RNA polymerase, insert domain (17.1%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (17.1%) DNA-directed RNA polymerase, alpha subunit (17.1%)" DFEGALDDYLALCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (100%) regulation of DNA-templated transcription (100%) "IPR008651 (33.3%) IPR010985 (33.3%) IPR035069 (33.3%)" "Uncharacterised protein family HicB (33.3%) Ribbon-helix-helix (33.3%) Antitoxin HicB/UPF0150 (33.3%)" LHGVDWEGYRK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR012393 (14.3%) IPR028204 (14.3%) IPR005151 (14.1%)" "Tricorn protease (14.3%) Tricorn protease C1 domain (14.3%) Tail specific protease (14.1%)" DYLAFVEEFLETK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" LDEFAEFR root 2.4.1.182 (100%) lipid-A-disaccharide synthase (100%) "GO:0009245 (18.6%) GO:0051301 (0.7%)" GO:0016020 (19.3%) "GO:0005543 (18.6%) GO:0008915 (18.6%) GO:0005524 (7.1%)" "lipid A biosynthetic process (18.6%) cell division (0.7%)" membrane (19.3%) "phospholipid binding (18.6%) lipid-A-disaccharide synthase activity (18.6%) ATP binding (7.1%)" "IPR003835 (25%) IPR027417 (9.6%) IPR000330 (6.7%)" "Glycosyl transferase, family 19 (25%) P-loop containing nucleoside triphosphate hydrolase (9.6%) SNF2, N-terminal (6.7%)" QDLYLTATEASTAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.4%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.4%) "IPR028994 (16.5%) IPR022045 (14.6%) IPR006530 (13.9%)" "Integrin alpha, N-terminal (16.5%) Insecticide toxin TcdB middle/N-terminal (14.6%) YD repeat (13.9%)" EDLLELLK root "2.7.7.6 (58.2%) 2.1.1.72 (3.9%) 3.1.4.- (3%)" "DNA-directed RNA polymerase (58.2%) site-specific DNA-methyltransferase (adenine-specific) (3.9%) Phosphoric diester hydrolases (3%)" "GO:0006351 (6%) GO:0006281 (2.6%) GO:0051301 (2.4%)" "GO:0000428 (6%) GO:0005634 (3.5%) GO:0005829 (1.6%)" "GO:0003677 (7.6%) GO:0003899 (6%) GO:0032549 (6%)" "DNA-templated transcription (6%) DNA repair (2.6%) cell division (2.4%)" "DNA-directed RNA polymerase complex (6%) nucleus (3.5%) cytosol (1.6%)" "DNA binding (7.6%) DNA-directed RNA polymerase activity (6%) ribonucleoside binding (6%)" "IPR007642 (3.8%) IPR015712 (3.8%) IPR007645 (3.7%)" "RNA polymerase Rpb2, domain 2 (3.8%) DNA-directed RNA polymerase, subunit 2 (3.8%) RNA polymerase Rpb2, domain 3 (3.7%)" VSQVYPLK Bacteria Bacteria GO:0016020 (10.4%) "GO:0000155 (29.2%) GO:0003700 (29.2%) GO:0043565 (29.2%)" membrane (10.4%) "phosphorelay sensor kinase activity (29.2%) DNA-binding transcription factor activity (29.2%) sequence-specific DNA binding (29.2%)" "IPR015943 (12.6%) IPR001789 (10.4%) IPR009057 (10.4%)" "WD40/YVTN repeat-like-containing domain superfamily (12.6%) Signal transduction response regulator, receiver domain (10.4%) Homedomain-like superfamily (10.4%)" GLTYAYR root "1.4.1.2 (64.3%) 2.7.11.30 (17.9%) 1.1.1.25 (3.6%)" "glutamate dehydrogenase (64.3%) receptor protein serine/threonine kinase (17.9%) shikimate dehydrogenase (NADP(+)) (3.6%)" "GO:0006412 (12.9%) GO:0000027 (11.5%) GO:0006538 (5.1%)" "GO:0005840 (12.9%) GO:1990904 (12.9%) GO:0005886 (0.5%)" "GO:0003735 (12.9%) GO:0019843 (12.9%) GO:0004069 (5.1%)" "translation (12.9%) ribosomal large subunit assembly (11.5%) L-glutamate catabolic process (5.1%)" "ribosome (12.9%) ribonucleoprotein complex (12.9%) plasma membrane (0.5%)" "structural constituent of ribosome (12.9%) rRNA binding (12.9%) L-aspartate:2-oxoglutarate aminotransferase activity (5.1%)" "IPR005813 (12.8%) IPR035566 (12.8%) IPR049946 (12.7%)" "Large ribosomal subunit protein bL20 (12.8%) Ribosomal protein bL20, C-terminal (12.8%) Large ribosomal subunit protein bL20, conserved site (12.7%)" AEEGVDLR root "4.1.1.17 (40%) 5.1.1.1 (40%) 7.2.2.9 (20%)" "ornithine decarboxylase (40%) alanine racemase (40%) P-type Cu(2+) transporter (20%)" "GO:0032049 (2%) GO:0030632 (1.4%) GO:0033387 (1.4%)" "GO:0005737 (6.1%) GO:0005829 (3.4%) GO:0005739 (0.7%)" "GO:0005524 (20.4%) GO:0140662 (18.4%) GO:0051082 (17.7%)" "cardiolipin biosynthetic process (2%) D-alanine biosynthetic process (1.4%) putrescine biosynthetic process from arginine, via ornithine (1.4%)" "cytoplasm (6.1%) cytosol (3.4%) mitochondrion (0.7%)" "ATP binding (20.4%) ATP-dependent protein folding chaperone (18.4%) unfolded protein binding (17.7%)" "IPR013126 (10.6%) IPR018181 (10.6%) IPR043129 (10.6%)" "Heat shock protein 70 family (10.6%) Heat shock protein 70, conserved site (10.6%) ATPase, nucleotide binding domain (10.6%)" EGSVWNTMPAHTHLR Pseudomonadati Bacteria Pseudomonadati 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.4%) IPR021120 (20.4%) IPR011051 (19.8%)" "5-keto 4-deoxyuronate isomerase (20.4%) KduI/IolB isomerase (20.4%) RmlC-like cupin domain superfamily (19.8%)" HVTAKEEEAELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.5%) IPR018223 (14.5%) IPR023434 (14.5%)" "Argininosuccinate synthase (14.5%) Argininosuccinate synthase, conserved site (14.5%) Argininosuccinate synthase, type 1 subfamily (14.5%)" DLDTNMLVNVSGHSPESYAECAAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.3.-.- (91.7%) 1.3.1.14 (8.3%)" "Acting on the CH-CH group of donors (91.7%) dihydroorotate dehydrogenase (NAD(+)) (8.3%)" "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" MTGSVTTLTSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.7%) IPR012910 (13.7%) IPR037066 (13.7%)" "Carboxypeptidase-like, regulatory domain superfamily (13.7%) TonB-dependent receptor, plug domain (13.7%) TonB-dependent receptor, plug domain superfamily (13.7%)" VTLPLAFSK root 3.2.1.185 (100%) non-reducing end beta-L-arabinofuranosidase (100%) "GO:0005975 (54.3%) GO:0006508 (0.3%) GO:0007339 (0.3%)" "GO:0016020 (1.1%) GO:0002079 (0.3%) GO:0002081 (0.3%)" "GO:0016787 (37.9%) GO:0102478 (2.4%) GO:0016798 (1.9%)" "carbohydrate metabolic process (54.3%) proteolysis (0.3%) binding of sperm to zona pellucida (0.3%)" "membrane (1.1%) inner acrosomal membrane (0.3%) outer acrosomal membrane (0.3%)" "hydrolase activity (37.9%) beta-L-arabinofuranosidase activity (2.4%) hydrolase activity, acting on glycosyl bonds (1.9%)" "IPR012878 (16.6%) IPR049174 (16.6%) IPR049046 (16.4%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.6%) Non-reducing end beta-L-arabinofuranosidase-like (16.6%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.4%)" YDPQAVESK Bacteria Bacteria 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.3%) GO:0005829 (20.3%) "GO:0004832 (20.3%) GO:0005524 (20.3%) GO:0002161 (18.7%)" valyl-tRNA aminoacylation (20.3%) cytosol (20.3%) "valine-tRNA ligase activity (20.3%) ATP binding (20.3%) aminoacyl-tRNA deacylase activity (18.7%)" "IPR001412 (9.5%) IPR002300 (9.5%) IPR002303 (9.5%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.5%) Aminoacyl-tRNA synthetase, class Ia (9.5%) Valine-tRNA ligase (9.5%)" AAEEGATLALSNTAMALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (34.1%) IPR014358 (34.1%) IPR036291 (31.8%)" "Short-chain dehydrogenase/reductase SDR (34.1%) Enoyl-[acyl-carrier-protein] reductase (NADH) (34.1%) NAD(P)-binding domain superfamily (31.8%)" DGLWLEK root "4.2.1.2 (98%) 1.2.1.41 (0.5%) 1.17.7.1 (0.1%)" "fumarate hydratase (98%) glutamate-5-semialdehyde dehydrogenase (0.5%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) (0.1%)" "GO:0006099 (19.7%) GO:0006091 (0.2%) GO:0055129 (0.1%)" "GO:0005737 (0.2%) GO:0005829 (0.1%) GO:0016020 (0.1%)" "GO:0051539 (20.2%) GO:0046872 (20.1%) GO:0004333 (20%)" "tricarboxylic acid cycle (19.7%) generation of precursor metabolites and energy (0.2%) L-proline biosynthetic process (0.1%)" "cytoplasm (0.2%) cytosol (0.1%) membrane (0.1%)" "4 iron, 4 sulfur cluster binding (20.2%) metal ion binding (20.1%) fumarate hydratase activity (20%)" "IPR051208 (16.6%) IPR004647 (16.5%) IPR004646 (16.4%)" "Class-I Fumarase/Tartrate Dehydratase (16.6%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (16.5%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (16.4%)" YGHFDDANREYVLTDPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (32.7%) "GO:0016757 (32.7%) GO:0030246 (32.7%) GO:0016740 (1.8%)" carbohydrate metabolic process (32.7%) "glycosyltransferase activity (32.7%) carbohydrate binding (32.7%) transferase activity (1.8%)" "IPR010383 (12.8%) IPR033432 (12.8%) IPR037825 (12.8%)" "Glycosyl hydrolase 94, supersandwich domain (12.8%) Glycosyl hydrolase 94, catalytic domain (12.8%) Cellobiose phosphorylase, N-terminal (12.8%)" FDLGNLQTQVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR045690 (100%) Protein of unknown function DUF6055 (100%) ASVASNLKVESK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" FNVLVVNNHSTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.8%) IPR013486 (12.8%) IPR013693 (12.8%)" "Glycosyltransferase 2-like (12.8%) Sporulation stage II protein D, amidase enhancer LytB (12.8%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.8%)" NQGEPLEEHYYTPYPGVSNKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" DEEAANKFTLLFNTLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.2%) IPR007644 (8.2%) IPR015712 (8.2%)" "RNA polymerase Rpb2, domain 2 (8.2%) RNA polymerase, beta subunit, protrusion (8.2%) DNA-directed RNA polymerase, subunit 2 (8.2%)" HGVYTGDFPTLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GPWEPLTWVMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" VETCPGVTCWQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (26.2%) IPR012131 (26.2%) IPR016161 (23.8%)" "Histidinol dehydrogenase, conserved site (26.2%) Histidinol dehydrogenase (26.2%) Aldehyde/histidinol dehydrogenase (23.8%)" EMYPTPDTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.1 (100%) pantoate--beta-alanine ligase (AMP-forming) (100%) GO:0015940 (25%) GO:0005829 (25%) "GO:0004592 (25%) GO:0005524 (25%)" pantothenate biosynthetic process (25%) cytosol (25%) "pantoate-beta-alanine ligase activity (25%) ATP binding (25%)" "IPR003721 (33.6%) IPR014729 (33.6%) IPR042176 (32.8%)" "Pantoate-beta-alanine ligase (33.6%) Rossmann-like alpha/beta/alpha sandwich fold (33.6%) Pantoate-beta-alanine ligase, C-terminal domain (32.8%)" MAAGMGADVWLTDLSLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.9%) GO:0005886 (25.9%) "GO:0000286 (25.9%) GO:0000166 (22.4%)" L-alanine catabolic process (25.9%) plasma membrane (25.9%) "alanine dehydrogenase activity (25.9%) nucleotide binding (22.4%)" "IPR007698 (20.3%) IPR007886 (20.3%) IPR008141 (20.3%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20.3%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20.3%) Alanine dehydrogenase (20.3%)" KSYAVNFLLQDEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0006432 (16.4%) GO:0006412 (0.3%)" "GO:0009328 (16.4%) GO:0005737 (0.3%)" "GO:0000049 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" "phenylalanyl-tRNA aminoacylation (16.4%) translation (0.3%)" "phenylalanine-tRNA ligase complex (16.4%) cytoplasm (0.3%)" "tRNA binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005121 (8%) IPR005147 (7.8%) IPR041616 (7.8%)" "Ferrodoxin-fold anticodon-binding domain (8%) tRNA synthetase, B5-domain (7.8%) Phenylalanyl tRNA synthetase beta chain, core domain (7.8%)" NLTLSYTFEPAWLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" HVLVPLVNR Bacteria Bacteria 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (19.9%) "GO:0005829 (19.9%) GO:0016020 (0.9%)" "GO:0004832 (19.9%) GO:0005524 (19.9%) GO:0002161 (19.3%)" valyl-tRNA aminoacylation (19.9%) "cytosol (19.9%) membrane (0.9%)" "valine-tRNA ligase activity (19.9%) ATP binding (19.9%) aminoacyl-tRNA deacylase activity (19.3%)" "IPR002300 (9.4%) IPR002303 (9.4%) IPR013155 (9.2%)" "Aminoacyl-tRNA synthetase, class Ia (9.4%) Valine-tRNA ligase (9.4%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (9.2%)" KAVDYLPEEWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" EELQMPFKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.9%) GO:0005737 (24.9%) "GO:0004821 (24.9%) GO:0005524 (24.9%) GO:0004812 (0.6%)" histidyl-tRNA aminoacylation (24.9%) cytoplasm (24.9%) "histidine-tRNA ligase activity (24.9%) ATP binding (24.9%) aminoacyl-tRNA ligase activity (0.6%)" "IPR041715 (12.8%) IPR004154 (12.5%) IPR006195 (12.5%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.8%) Anticodon-binding (12.5%) Aminoacyl-tRNA synthetase, class II (12.5%)" MLNPNDLESFTVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" ALLDEVVYSLLYSASDKPLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) "GO:0007234 (10.6%) GO:0016036 (3.5%)" "GO:0005886 (20.6%) GO:0016020 (0.7%)" "GO:0000155 (21.3%) GO:0005524 (18.4%) GO:0000156 (10.6%)" "osmosensory signaling via phosphorelay pathway (10.6%) cellular response to phosphate starvation (3.5%)" "plasma membrane (20.6%) membrane (0.7%)" "phosphorelay sensor kinase activity (21.3%) ATP binding (18.4%) phosphorelay response regulator activity (10.6%)" "IPR003661 (15.5%) IPR003594 (15%) IPR005467 (15%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (15.5%) Histidine kinase/HSP90-like ATPase domain (15%) Histidine kinase domain (15%)" SQVTLEYSDDNLPQR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004478 (16.7%) GO:0005524 (16.7%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) methionine adenosyltransferase activity (16.7%) ATP binding (16.7%)" "IPR002133 (16.7%) IPR022628 (16.7%) IPR022629 (16.7%)" "S-adenosylmethionine synthetase (16.7%) S-adenosylmethionine synthetase, N-terminal (16.7%) S-adenosylmethionine synthetase, central domain (16.7%)" NLSWDSGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ALQVQEEGTENR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" NYQLYVEQFYDMLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR007139 (100%) Protein of unknown function DUF349 (100%) YTAMGVDNYQDYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" MVLGVPSGSTEVELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000902 (25.4%) GO:0008360 (25.4%) GO:0043093 (0.1%)" "GO:0005737 (25.4%) GO:0005856 (0.1%) GO:0005886 (0.1%)" "GO:0005524 (23.1%) GO:0016787 (0.4%)" "cell morphogenesis (25.4%) regulation of cell shape (25.4%) FtsZ-dependent cytokinesis (0.1%)" "cytoplasm (25.4%) cytoskeleton (0.1%) plasma membrane (0.1%)" "ATP binding (23.1%) hydrolase activity (0.4%)" "IPR004753 (32.6%) IPR043129 (32.6%) IPR056546 (32.6%)" "Cell shape determining protein MreB (32.6%) ATPase, nucleotide binding domain (32.6%) MreB/MamK-like (32.6%)" TSLLLDLFAMR Bacteria Bacteria GO:0005737 (20.2%) "GO:0005525 (20.2%) GO:0043022 (20.2%) GO:0046872 (20.2%)" cytoplasm (20.2%) "GTP binding (20.2%) ribosome binding (20.2%) metal ion binding (20.2%)" "IPR006073 (13.2%) IPR016496 (13.2%) IPR025121 (13.2%)" "GTP binding domain (13.2%) GTPase HflX (13.2%) GTPase HflX, N-terminal (13.2%)" ADYTQVDFLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025634 (100%) Protein of unknown function DUF4292 (100%) LLNLVNQLLDFR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.13.3 (100%) histidine kinase (100%) GO:0006508 (0.1%) GO:0016020 (13.1%) "GO:0000155 (22.6%) GO:0003700 (22.4%) GO:0043565 (22.4%)" proteolysis (0.1%) membrane (13.1%) "phosphorelay sensor kinase activity (22.6%) DNA-binding transcription factor activity (22.4%) sequence-specific DNA binding (22.4%)" "IPR003594 (6.8%) IPR005467 (6.8%) IPR018060 (6.7%)" "Histidine kinase/HSP90-like ATPase domain (6.8%) Histidine kinase domain (6.8%) AraC-like, DNA binding HTH domain (6.7%)" QEQLGLYEVSPEDFAVAEFVDSSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "7.2.1.1 (97.7%) 1.6.5.- (2.3%)" "NADH:ubiquinone reductase (Na(+)-transporting) (97.7%) With a quinone or similar compound as acceptor (2.3%)" GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (21.4%) IPR022615 (20.9%) IPR056147 (20.9%)" "Na(+)-translocating NADH-quinone reductase subunit A (21.4%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.9%) NqrA, N-terminal barrel-sandwich hybrid domain (20.9%)" AGGYNLQMFSDLLQTELNANR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006826 (46.9%) GO:0006811 (3.1%)" GO:0009279 (50%) "iron ion transport (46.9%) monoatomic ion transport (3.1%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" FYVMAENLLTWTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" GQENAGNVLGAALVYSGNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (13%) IPR031704 (13%) IPR031705 (13%)" "Glycoside hydrolase family 36 (13%) Glycosyl hydrolase family 36, N-terminal (13%) Glycosyl hydrolase family 36, C-terminal (13%)" VLMWDVVTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.-.-.- (66.7%) 3.5.1.104 (33.3%)" "Hydrolases (66.7%) peptidoglycan-N-acetylglucosamine deacetylase (33.3%)" GO:0005975 (33.3%) GO:0016020 (33.3%) GO:0016810 (33.3%) carbohydrate metabolic process (33.3%) membrane (33.3%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (33.3%) "IPR002509 (33.3%) IPR011330 (33.3%) IPR050248 (33.3%)" "NodB homology domain (33.3%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (33.3%) Polysaccharide deacetylase, ArnD subfamily (33.3%)" LEVLDALSALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR041538 (17.6%) IPR045427 (17.6%) IPR050513 (17.6%)" "ATPase RavA-like, AAA lid domain (17.6%) MoxR domain (17.6%) RavA family ATPases (17.6%)" NFEEALQK root "6.3.5.5 (50.5%) 6.3.4.16 (25.3%) 2.1.3.2 (10.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.5%) carbamoyl-phosphate synthase (ammonia) (25.3%) aspartate carbamoyltransferase (10.5%)" "GO:0006541 (11.7%) GO:0006526 (10.2%) GO:0006221 (7.3%)" "GO:0005737 (7.7%) GO:0005951 (3.4%) GO:0005829 (1.2%)" "GO:0005524 (11.9%) GO:0004088 (11.7%) GO:0046872 (11.5%)" "glutamine metabolic process (11.7%) L-arginine biosynthetic process (10.2%) pyrimidine nucleotide biosynthetic process (7.3%)" "cytoplasm (7.7%) carbamoyl-phosphate synthase complex (3.4%) cytosol (1.2%)" "ATP binding (11.9%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (11.7%) metal ion binding (11.5%)" "IPR016185 (8%) IPR005480 (8%) IPR011761 (8%)" "Pre-ATP-grasp domain superfamily (8%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (8%) ATP-grasp fold (8%)" GVVLDKGPNGPLSNTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (58.8%) "GO:0016787 (23.5%) GO:0016829 (17.6%)" carbohydrate metabolic process (58.8%) "hydrolase activity (23.5%) lyase activity (17.6%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" LEVLDGLEK root "5.1.3.2 (90.1%) 3.4.19.12 (9%) 1.3.1.14 (0.9%)" "UDP-glucose 4-epimerase (90.1%) ubiquitinyl hydrolase 1 (9%) dihydroorotate dehydrogenase (NAD(+)) (0.9%)" "GO:0006012 (27.1%) GO:0006508 (2.9%) GO:0016579 (2.7%)" "GO:0005829 (30.1%) GO:0005634 (2.9%) GO:0005615 (0.3%)" "GO:0003978 (27.1%) GO:0004843 (2.9%) GO:0000976 (0.3%)" "galactose metabolic process (27.1%) proteolysis (2.9%) protein deubiquitination (2.7%)" "cytosol (30.1%) nucleus (2.9%) extracellular space (0.3%)" "UDP-glucose 4-epimerase activity (27.1%) cysteine-type deubiquitinase activity (2.9%) transcription cis-regulatory region binding (0.3%)" "IPR036291 (25.7%) IPR005886 (25.4%) IPR016040 (20.3%)" "NAD(P)-binding domain superfamily (25.7%) UDP-glucose 4-epimerase (25.4%) NAD(P)-binding domain (20.3%)" NSHTDHAEVMFSLDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR031704 (13.2%) IPR002252 (12.8%) IPR031705 (12.8%)" "Glycosyl hydrolase family 36, N-terminal (13.2%) Glycoside hydrolase family 36 (12.8%) Glycosyl hydrolase family 36, C-terminal (12.8%)" KGTSVDVLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR032252 (51.3%) IPR046357 (48.7%)" "Protein of unknown function DUF4827 (51.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (48.7%)" LSASWSVR root "GO:0044718 (31.1%) GO:0006310 (0.8%) GO:0032196 (0.8%)" "GO:0009279 (31.1%) GO:0005737 (0.8%) GO:0032153 (0.8%)" "GO:0015344 (31.1%) GO:0003677 (0.8%) GO:0003924 (0.8%)" "siderophore transmembrane transport (31.1%) DNA recombination (0.8%) transposition (0.8%)" "cell outer membrane (31.1%) cytoplasm (0.8%) cell division site (0.8%)" "siderophore uptake transmembrane transporter activity (31.1%) DNA binding (0.8%) GTPase activity (0.8%)" "IPR000531 (19.6%) IPR012910 (19.6%) IPR039426 (19.6%)" "TonB-dependent receptor-like, beta-barrel (19.6%) TonB-dependent receptor, plug domain (19.6%) TonB-dependent receptor-like (19.6%)" ELHDALEASVKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" YTPDLSVVYGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.6%) IPR033985 (34.6%) IPR012944 (30.8%)" "Tetratricopeptide-like helical domain superfamily (34.6%) SusD-like, N-terminal (34.6%) RagB/SusD domain (30.8%)" LWLFNANDGSLVEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) ALVALGNLLAMNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.6%) IPR011990 (47.4%)" "Tetratricopeptide repeat (52.6%) Tetratricopeptide-like helical domain superfamily (47.4%)" RPLQFSVGAYYSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0071709 (48.3%) "GO:0009279 (48.3%) GO:0019867 (3.3%)" membrane assembly (48.3%) "cell outer membrane (48.3%) outer membrane (3.3%)" "IPR010827 (26.1%) IPR034746 (25.2%) IPR023707 (24.4%)" "POTRA domain, BamA/TamA-like (26.1%) POTRA domain (25.2%) Outer membrane protein assembly factor BamA (24.4%)" MACGVGACLCCVEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.5.2 (100%) dihydroorotate dehydrogenase (quinone) (100%) "GO:0044205 (11.5%) GO:0006221 (6.1%)" "GO:0016491 (17.8%) GO:0046872 (17.6%) GO:0050660 (17.6%)" "'de novo' UMP biosynthetic process (11.5%) pyrimidine nucleotide biosynthetic process (6.1%)" "oxidoreductase activity (17.8%) metal ion binding (17.6%) flavin adenine dinucleotide binding (17.6%)" "IPR019480 (11.8%) IPR050353 (11.8%) IPR037117 (11.6%)" "Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.8%) Dihydroorotate dehydrogenase B electron transfer subunit (11.8%) Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily (11.6%)" VFEVNFEYNAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.6%) IPR033985 (34.6%) IPR012944 (30.8%)" "Tetratricopeptide-like helical domain superfamily (34.6%) SusD-like, N-terminal (34.6%) RagB/SusD domain (30.8%)" VFMSFALATGTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (25.7%) IPR003593 (25.7%) IPR027417 (24.3%)" "ABC transporter-like, ATP-binding domain (25.7%) AAA+ ATPase domain (25.7%) P-loop containing nucleoside triphosphate hydrolase (24.3%)" YSLQGMR root "GO:0044718 (28.8%) GO:0016485 (0.9%) GO:0000271 (0.4%)" "GO:0009279 (28.8%) GO:0005886 (0.9%) GO:0016020 (0.9%)" "GO:0015344 (28.8%) GO:0004180 (4%) GO:0046872 (1.3%)" "siderophore transmembrane transport (28.8%) protein processing (0.9%) polysaccharide biosynthetic process (0.4%)" "cell outer membrane (28.8%) plasma membrane (0.9%) membrane (0.9%)" "siderophore uptake transmembrane transporter activity (28.8%) carboxypeptidase activity (4%) metal ion binding (1.3%)" "IPR039426 (18.3%) IPR057601 (18.3%) IPR008969 (18.1%)" "TonB-dependent receptor-like (18.3%) TonB-dependent transporter Oar-like, beta-barrel domain (18.3%) Carboxypeptidase-like, regulatory domain superfamily (18.1%)" YSVVSAMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "7.1.1.- (90.3%) 1.6.5.11 (4.8%) 1.6.5.9 (4.8%)" "Hydron translocation or charge separation linked to oxidoreductase reactions (90.3%) Transferred entry: 1.6.5.9 (4.8%) NADH:ubiquinone reductase (non-electrogenic) (4.8%)" GO:0009060 (20.1%) "GO:0005886 (19.8%) GO:0016020 (0.4%)" "GO:0003954 (20.1%) GO:0016655 (19.8%) GO:0048038 (19.8%)" aerobic respiration (20.1%) "plasma membrane (19.8%) membrane (0.4%)" "NADH dehydrogenase activity (20.1%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (19.8%) quinone binding (19.8%)" "IPR001694 (50%) IPR018086 (50%)" "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H (50%) NADH:ubiquinone oxidoreductase, subunit 1, conserved site (50%)" TQAENQMFNWLSNLLHWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.6%) IPR015171 (14.6%) IPR019492 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (14.6%) Cyclomaltodextrinase, N-terminal (14.6%) Cyclo-malto-dextrinase, C-terminal (14.6%)" ARLEQLEPMELAQYYTNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.16 (100%) cysteine--tRNA ligase (100%) GO:0006423 (20%) GO:0005829 (20%) "GO:0004817 (20%) GO:0005524 (20%) GO:0008270 (19.6%)" cysteinyl-tRNA aminoacylation (20%) cytosol (20%) "cysteine-tRNA ligase activity (20%) ATP binding (20%) zinc ion binding (19.6%)" "IPR009080 (14.4%) IPR014729 (14.4%) IPR015273 (14.4%)" "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (14.4%) Rossmann-like alpha/beta/alpha sandwich fold (14.4%) Cysteinyl-tRNA synthetase, class Ia, DALR (14.4%)" LKDGTVALCDNAFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026906 (33.3%) IPR032675 (33.3%) IPR053139 (33.3%)" "BspA-type LRR region (33.3%) Leucine-rich repeat domain superfamily (33.3%) Putative surface bspA-like protein (33.3%)" DDLESLHATLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) YVDDLASR root "3.1.-.- (20%) 3.2.1.- (20%) 4.6.1.1 (20%)" "Acting on ester bonds (20%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (20%) adenylate cyclase (20%)" "GO:0006508 (3.2%) GO:0006265 (1.1%) GO:0008360 (1.1%)" GO:0005737 (37.2%) "GO:0016149 (37.2%) GO:0008236 (2.1%) GO:0008239 (2.1%)" "proteolysis (3.2%) DNA topological change (1.1%) regulation of cell shape (1.1%)" cytoplasm (37.2%) "translation release factor activity, codon specific (37.2%) serine-type peptidase activity (2.1%) dipeptidyl-peptidase activity (2.1%)" "IPR000352 (14.3%) IPR050057 (14.3%) IPR004373 (13.9%)" "Peptide chain release factor class I (14.3%) Prokaryotic/Mitochondrial Release Factor (14.3%) Peptide chain release factor 1 (13.9%)" SVNLADLDAEGKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) CVANSELLNDLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" YLGANFVHDDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" NPYASLTR root 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009088 (1.4%) GO:0009089 (1.4%) GO:0009090 (1.4%)" "GO:0009279 (2.9%) GO:0005829 (1.4%) GO:0009570 (1.4%)" "GO:0003700 (41.4%) GO:0043565 (41.4%) GO:0004072 (1.4%)" "threonine biosynthetic process (1.4%) lysine biosynthetic process via diaminopimelate (1.4%) homoserine biosynthetic process (1.4%)" "cell outer membrane (2.9%) cytosol (1.4%) chloroplast stroma (1.4%)" "DNA-binding transcription factor activity (41.4%) sequence-specific DNA binding (41.4%) aspartate kinase activity (1.4%)" "IPR018060 (21.3%) IPR018062 (21.3%) IPR009057 (19.9%)" "AraC-like, DNA binding HTH domain (21.3%) HTH domain AraC-type, conserved site (21.3%) Homedomain-like superfamily (19.9%)" MGEPLGETPALGPWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (12.5%) GO:0044210 (12.5%)" "GO:0005829 (12.5%) GO:0097268 (12.5%)" "GO:0003883 (12.5%) GO:0005524 (12.5%) GO:0042802 (12.5%)" "pyrimidine nucleobase biosynthetic process (12.5%) 'de novo' CTP biosynthetic process (12.5%)" "cytosol (12.5%) cytoophidium (12.5%)" "CTP synthase activity (12.5%) ATP binding (12.5%) identical protein binding (12.5%)" "IPR004468 (16.7%) IPR017456 (16.7%) IPR017926 (16.7%)" "CTP synthase (16.7%) CTP synthase, N-terminal (16.7%) Glutamine amidotransferase (16.7%)" DANKLVEEFMLLANR Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.1.13.1 (99.3%) 3.1.-.- (0.7%)" "exoribonuclease II (99.3%) Acting on ester bonds (0.7%)" GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (24.8%) GO:0004527 (0.2%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (24.8%) exonuclease activity (0.2%)" "IPR001900 (12.5%) IPR040476 (12.5%) IPR050180 (12.5%)" "Ribonuclease II/R (12.5%) RNase II/RNase R, cold shock domain (12.5%) RNR Ribonuclease (12.5%)" RGELLNQEYVSGNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.0 (100%) Unknown (100%) GO:0045727 (16.7%) GO:0005886 (16.7%) "GO:0003746 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" positive regulation of translation (16.7%) plasma membrane (16.7%) "translation elongation factor activity (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR000640 (9.7%) IPR000795 (9.7%) IPR004161 (9.7%)" "Elongation factor EFG, domain V-like (9.7%) Translational (tr)-type GTP-binding domain (9.7%) Translation elongation factor EFTu-like, domain 2 (9.7%)" SHNSLVSYFGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR023996 (13.8%) IPR023997 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.8%)" VEMEQEAEPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR000089 (25%) IPR001882 (25%) IPR011053 (25%)" "Biotin/lipoyl attachment (25%) Biotin-binding site (25%) Single hybrid motif (25%)" GKHEFFPYPQTVMDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (30%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (30%)" TEFTVHNGDVFWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" EMAQLYGYDLSQPAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.5%) GO:0005829 (33.7%) GO:0008861 (33.7%) glucose metabolic process (32.5%) cytosol (33.7%) formate C-acetyltransferase activity (33.7%) "IPR004184 (20.4%) IPR050244 (20.4%) IPR001150 (19.7%)" "Pyruvate formate lyase domain (20.4%) Autonomous Glycyl Radical Cofactor (20.4%) Glycine radical domain (19.7%)" AVTQHFEDLGQDASVHDVTYENSQAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.1 (100%) NAD(+) synthase (glutamine-hydrolyzing) (100%) GO:0009435 (16.9%) GO:0005737 (16.9%) "GO:0003952 (16.9%) GO:0004359 (16.9%) GO:0005524 (16.3%)" NAD+ biosynthetic process (16.9%) cytoplasm (16.9%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.9%) glutaminase activity (16.9%) ATP binding (16.3%)" "IPR003694 (15.3%) IPR022310 (15.3%) IPR003010 (14.8%)" "NAD(+) synthetase (15.3%) NAD/GMP synthase (15.3%) Carbon-nitrogen hydrolase (14.8%)" NWTFENQTPNKDQNGNLATLTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR001179 (50%) IPR046357 (50%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (50%) Peptidyl-prolyl cis-trans isomerase domain superfamily (50%)" FASEGANLAFTDLVLNDDMAAGLEATR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) GO:0006633 (33.3%) "GO:0004316 (33.3%) GO:0051287 (33.3%)" fatty acid biosynthetic process (33.3%) "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (33.3%) NAD binding (33.3%)" "IPR002347 (17.9%) IPR050259 (17.9%) IPR036291 (16.7%)" "Short-chain dehydrogenase/reductase SDR (17.9%) Short-chain dehydrogenases/reductases (17.9%) NAD(P)-binding domain superfamily (16.7%)" GVDSNGNPYLLTDEYGHKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FVNSLAGFR root "IPR025684 (49.2%) IPR026377 (49.2%) IPR032675 (1.5%)" "Gliding motility protein SprA N-terminal domain (49.2%) Cell surface SprA (49.2%) Leucine-rich repeat domain superfamily (1.5%)" TLTSSDEDLDGLMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009055 (100%) electron transfer activity (100%) "IPR000049 (20%) IPR012255 (20%) IPR014729 (20%)" "Electron transfer flavoprotein, beta-subunit, conserved site (20%) Electron transfer flavoprotein, beta subunit (20%) Rossmann-like alpha/beta/alpha sandwich fold (20%)" TEDGKLDYSDDFFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.4%) GO:0005737 (19.5%) "GO:0005524 (20.4%) GO:0003676 (19.5%) GO:0004816 (19.5%)" asparaginyl-tRNA aminoacylation (20.4%) cytoplasm (19.5%) "ATP binding (20.4%) nucleic acid binding (19.5%) asparagine-tRNA ligase activity (19.5%)" "IPR004364 (14.9%) IPR006195 (14.9%) IPR004365 (14.3%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (14.9%) Aminoacyl-tRNA synthetase, class II (14.9%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (14.3%)" LNQEWLPTYESGATLYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (14.7%) GO:0009098 (14.7%) GO:0009099 (14.7%)" "GO:0004084 (19.9%) GO:0052654 (5.1%) GO:0052655 (5.1%)" "isoleucine biosynthetic process (14.7%) L-leucine biosynthetic process (14.7%) L-valine biosynthetic process (14.7%)" "branched-chain-amino-acid transaminase activity (19.9%) L-leucine-2-oxoglutarate transaminase activity (5.1%) L-valine-2-oxoglutarate transaminase activity (5.1%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" KQGGGEQATMSMEEFAQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" NQNPLLTLESCDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" ANDECVPVTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (33.3%) IPR020845 (33.3%) IPR042099 (33.3%)" "AMP-dependent synthetase/ligase domain (33.3%) AMP-binding, conserved site (33.3%) ANL, N-terminal domain (33.3%)" HLEEGLMK root "4.1.1.35 (50%) 6.3.4.2 (50%)" "UDP-glucuronate decarboxylase (50%) CTP synthase (glutamine hydrolyzing) (50%)" "GO:0019856 (5.7%) GO:0042732 (5.7%) GO:0044210 (5.7%)" "GO:0005737 (6.1%) GO:0016020 (6.1%) GO:0005829 (5.7%)" "GO:0005524 (6.1%) GO:0046872 (6.1%) GO:0003883 (5.7%)" "pyrimidine nucleobase biosynthetic process (5.7%) D-xylose metabolic process (5.7%) 'de novo' CTP biosynthetic process (5.7%)" "cytoplasm (6.1%) membrane (6.1%) cytosol (5.7%)" "ATP binding (6.1%) metal ion binding (6.1%) CTP synthase activity (5.7%)" "IPR027417 (8.2%) IPR004468 (7.2%) IPR016040 (7.2%)" "P-loop containing nucleoside triphosphate hydrolase (8.2%) CTP synthase (7.2%) NAD(P)-binding domain (7.2%)" YYLQASLR root "2.4.1.25 (50%) 3.2.1.33 (50%)" "4-alpha-glucanotransferase (50%) amylo-alpha-1,6-glucosidase (50%)" "GO:0044718 (5.9%) GO:0005978 (2.9%) GO:0005980 (2.9%)" "GO:0009279 (61.8%) GO:0005737 (2.9%)" "GO:0005507 (5.9%) GO:0015344 (5.9%) GO:0016491 (5.9%)" "siderophore transmembrane transport (5.9%) glycogen biosynthetic process (2.9%) glycogen catabolic process (2.9%)" "cell outer membrane (61.8%) cytoplasm (2.9%)" "copper ion binding (5.9%) siderophore uptake transmembrane transporter activity (5.9%) oxidoreductase activity (5.9%)" "IPR012910 (11.3%) IPR023996 (11.3%) IPR023997 (11.3%)" "TonB-dependent receptor, plug domain (11.3%) TonB-dependent outer membrane protein, SusC/RagA (11.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (11.3%)" LVEAVSVLNTGGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) GO:0006265 (19.7%) "GO:0003677 (19.7%) GO:0003918 (19.7%) GO:0005524 (19.7%)" DNA topological change (19.7%) "DNA binding (19.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (19.7%) ATP binding (19.7%)" "IPR003594 (9.3%) IPR001241 (9.2%) IPR013506 (9.2%)" "Histidine kinase/HSP90-like ATPase domain (9.3%) DNA topoisomerase, type IIA (9.2%) DNA topoisomerase, type IIA, subunit B, domain 2 (9.2%)" ELAESELR root "2.7.7.48 (60.4%) 2.1.1.72 (5.7%) 2.7.13.3 (5.7%)" "RNA-directed RNA polymerase (60.4%) site-specific DNA-methyltransferase (adenine-specific) (5.7%) histidine kinase (5.7%)" "GO:0006351 (4.1%) GO:0039694 (3.9%) GO:0006508 (2.3%)" "GO:0005886 (4.8%) GO:0044165 (3.7%) GO:0044172 (3.7%)" "GO:0003968 (4.1%) GO:0016787 (3.6%) GO:0005524 (2.5%)" "DNA-templated transcription (4.1%) viral RNA genome replication (3.9%) proteolysis (2.3%)" "plasma membrane (4.8%) host cell endoplasmic reticulum (3.7%) host cell endoplasmic reticulum-Golgi intermediate compartment (3.7%)" "RNA-directed RNA polymerase activity (4.1%) hydrolase activity (3.6%) ATP binding (2.5%)" "IPR007099 (4.2%) IPR007322 (4.2%) IPR048547 (4.2%)" "RNA-directed RNA polymerase, negative-strand RNA virus (4.2%) RNA-dependent RNA polymerase, bunyaviral (4.2%) RNA-directed RNA polymerase L, thumb ring domain, bunyaviral (4.2%)" HYGLDVGYPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005829 (50%) GO:0016491 (50%) cytosol (50%) oxidoreductase activity (50%) IPR004017 (100%) Cysteine-rich domain (100%) LPDYFLSDLSDTDER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.1.32 (100%) phospholipase A1 (100%) GO:0016020 (49.7%) "GO:0046873 (49.7%) GO:0008970 (0.6%)" membrane (49.7%) "metal ion transmembrane transporter activity (49.7%) phospholipase A1 activity (0.6%)" "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" MDTGAPVVTPSEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ELVLSHLANQLNFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003677 (50%) GO:0003700 (50%)" "DNA binding (50%) DNA-binding transcription factor activity (50%)" "IPR000524 (20%) IPR008920 (20%) IPR011711 (20%)" "Transcription regulator HTH, GntR (20%) Transcription regulator FadR/GntR, C-terminal (20%) GntR, C-terminal (20%)" SEDKYLLR root "GO:0097009 (15.6%) GO:0030030 (2.2%) GO:0032957 (2.2%)" "GO:0005616 (15.6%) GO:0005737 (4.4%) GO:0005829 (2.2%)" "GO:0045735 (15.6%) GO:0005524 (4.4%) GO:0000287 (2.2%)" "energy homeostasis (15.6%) cell projection organization (2.2%) inositol trisphosphate metabolic process (2.2%)" "larval serum protein complex (15.6%) cytoplasm (4.4%) cytosol (2.2%)" "nutrient reservoir activity (15.6%) ATP binding (4.4%) magnesium ion binding (2.2%)" "IPR000896 (8.6%) IPR005203 (8.6%) IPR005204 (8.6%)" "Hemocyanin/hexamerin middle domain (8.6%) Hemocyanin, C-terminal (8.6%) Hemocyanin, N-terminal (8.6%)" VYVQAMNPFTLYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" ASPLVNFTDLEHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (57.1%) IPR042278 (42.9%)" "Fimbrillin-like 1 (57.1%) Fimbrillin-like 1, N-terminal (42.9%)" ANLLLQVVASEWGALGGPFQYGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033985 (54.5%) IPR011990 (45.5%)" "SusD-like, N-terminal (54.5%) Tetratricopeptide-like helical domain superfamily (45.5%)" FKFGNLK root "2.7.7.7 (60%) 3.2.1.21 (40%)" "DNA-directed DNA polymerase (60%) beta-glucosidase (40%)" "GO:0006271 (3.8%) GO:0045944 (2.1%) GO:0050832 (1.7%)" "GO:0016020 (21.6%) GO:0005737 (4.7%) GO:0009360 (3.8%)" "GO:0003677 (5.1%) GO:0008270 (4.2%) GO:0000981 (3.8%)" "DNA strand elongation involved in DNA replication (3.8%) positive regulation of transcription by RNA polymerase II (2.1%) defense response to fungus (1.7%)" "membrane (21.6%) cytoplasm (4.7%) DNA polymerase III complex (3.8%)" "DNA binding (5.1%) zinc ion binding (4.2%) DNA-binding transcription factor activity, RNA polymerase II-specific (3.8%)" "IPR052724 (13.2%) IPR021280 (12.5%) IPR001001 (3%)" "Glycosyltransferase 117 domain-containing protein (13.2%) Protein O-mannosyl-transferase TMEM260-like (12.5%) DNA polymerase III, beta sliding clamp (3%)" LGVSPLQDVLNAMTLDEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) "GO:0008422 (47.2%) GO:0004553 (2.8%)" carbohydrate metabolic process (50%) "beta-glucosidase activity (47.2%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.8%)" "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" VNFELQGAAGALSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) GHLYQQNCMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (26.6%) IPR013780 (25%) IPR017853 (25%)" "Alpha-L-arabinofuranosidase, C-terminal (26.6%) Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%)" LAFSLYEFMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae TNLLGLATTSLNAGLELGTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) WNLSTTPDWMNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" AGYGELFFSDMDDDDKWYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027848 (100%) Protein of unknown function DUF4494 (100%) AMNEAYANDGFENPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" LSQLANLYYNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR021272 (100%) Protein of unknown function DUF2851 (100%) QEAETLAFSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" YEMCGLRPSFYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.1.22 (100%) NAD(+) diphosphatase (100%) "GO:0006734 (16.6%) GO:0006742 (16.6%) GO:0019677 (16.6%)" GO:0005829 (15.9%) "GO:0035529 (16.6%) GO:0046872 (16.6%) GO:0110153 (1.4%)" "obsolete NADH metabolic process (16.6%) NADP+ catabolic process (16.6%) NAD+ catabolic process (16.6%)" cytosol (15.9%) "NADH pyrophosphatase activity (16.6%) metal ion binding (16.6%) RNA NAD-cap (NMN-forming) hydrolase activity (1.4%)" "IPR000086 (14.5%) IPR015375 (14.5%) IPR020084 (14.5%)" "NUDIX hydrolase domain (14.5%) NADH pyrophosphatase-like, N-terminal (14.5%) NUDIX hydrolase, conserved site (14.5%)" TEFVDSLFK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (16.7%) "GO:0005737 (16.7%) GO:0005886 (16.7%)" "GO:0003924 (16.7%) GO:0005047 (16.7%) GO:0005525 (16.7%)" SRP-dependent cotranslational protein targeting to membrane (16.7%) "cytoplasm (16.7%) plasma membrane (16.7%)" "GTPase activity (16.7%) signal recognition particle binding (16.7%) GTP binding (16.7%)" "IPR000897 (14.6%) IPR003593 (14.6%) IPR004390 (14.6%)" "Signal recognition particle, SRP54 subunit, GTPase domain (14.6%) AAA+ ATPase domain (14.6%) Signal-recognition particle receptor FtsY (14.6%)" NCVFDGSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) YWTLNEQVLFNLSNMFCGYNEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (25%) IPR011250 (25%) IPR036737 (25%)" "OmpA-like domain (25%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (25%) OmpA-like domain superfamily (25%)" LGTYYFEEAVAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016301 (97.1%) GO:0047590 (2.9%)" "kinase activity (97.1%) 5-dehydro-2-deoxygluconokinase activity (2.9%)" "IPR011611 (34.3%) IPR052700 (34.3%) IPR029056 (31.4%)" "Carbohydrate kinase PfkB (34.3%) Carbohydrate kinase PfkB-like (34.3%) Ribokinase-like (31.4%)" MFLSVMCHSYCEEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0005737 (12.5%) GO:0070062 (12.5%) GO:1990742 (12.5%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "cytoplasm (12.5%) extracellular exosome (12.5%) microvesicle (12.5%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.5%) IPR004154 (11.5%) IPR006195 (11.5%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.5%) Anticodon-binding (11.5%) Aminoacyl-tRNA synthetase, class II (11.5%)" FGNTWQLVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) DLNNFYYETDVDDLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.9%) GO:0005737 (48.9%)" GO:0016787 (2.1%) "extracellular region (48.9%) cytoplasm (48.9%)" hydrolase activity (2.1%) "IPR006530 (16.3%) IPR050708 (15.8%) IPR031325 (15.3%)" "YD repeat (16.3%) Type VI secretion system VgrG/RHS (15.8%) RHS repeat (15.3%)" THTYLVEHTDAPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR027417 (35%) IPR041682 (35%) IPR036390 (30%)" "P-loop containing nucleoside triphosphate hydrolase (35%) AAA domain, group 14 (35%) Winged helix DNA-binding domain superfamily (30%)" FLCLDDDVYHLGASLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR018873 (100%) KilA-N, DNA-binding domain (100%) KLDQENSNYYSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" SYPFSEDALKEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003677 (100%) DNA binding (100%) "IPR041607 (26.9%) IPR010992 (25.4%) IPR036388 (23.9%)" "HU domain fused to wHTH, Ig, or Glycine-rich motif (26.9%) Integration host factor (IHF)-like DNA-binding domain superfamily (25.4%) Winged helix-like DNA-binding domain superfamily (23.9%)" FNVTATVGLQTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VMLNQELVASNYSFLWNGVTSPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NLVFQAK root "2.7.11.1 (48.8%) 1.3.1.108 (12.2%) 3.6.3.17 (12.2%)" "non-specific serine/threonine protein kinase (48.8%) caffeoyl-CoA reductase (12.2%) Transferred entry: 7.5.2.8 (12.2%)" "GO:0006420 (0.7%) GO:0006426 (0.7%) GO:0000460 (0.4%)" "GO:0005886 (7%) GO:0016020 (2.2%) GO:0005829 (0.9%)" "GO:0009055 (53%) GO:0005524 (8.4%) GO:0004674 (4.2%)" "arginyl-tRNA aminoacylation (0.7%) glycyl-tRNA aminoacylation (0.7%) maturation of 5.8S rRNA (0.4%)" "plasma membrane (7%) membrane (2.2%) cytosol (0.9%)" "electron transfer activity (53%) ATP binding (8.4%) protein serine/threonine kinase activity (4.2%)" "IPR014729 (16.9%) IPR012255 (16.6%) IPR014730 (16.5%)" "Rossmann-like alpha/beta/alpha sandwich fold (16.9%) Electron transfer flavoprotein, beta subunit (16.6%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (16.5%)" TDVCLVDTETGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) FNSEQLTWDQNKHELSSNVFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0015221 (50%) plasma membrane (50%) lipopolysaccharide transmembrane transporter activity (50%) "IPR010664 (50%) IPR026265 (50%)" "Lipopolysaccharide assembly, LptC-related (50%) Lipopolysaccharide export system protein LptC (50%)" TQCVLSSWNPYNLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) "IPR003423 (50%) IPR050737 (50%)" "Outer membrane efflux protein (50%) Unknown (50%)" ALDPALAAK root "2.7.7.7 (53.8%) 1.1.2.- (7.7%) 1.8.4.11 (7.7%)" "DNA-directed DNA polymerase (53.8%) With a cytochrome as acceptor (7.7%) peptide-methionine (S)-S-oxide reductase (7.7%)" "GO:0017004 (16.7%) GO:0045454 (16.7%) GO:0006261 (1.8%)" "GO:0005886 (16.1%) GO:0016020 (3%) GO:0005737 (0.6%)" "GO:0015035 (16.7%) GO:0003677 (2.4%) GO:0003887 (1.8%)" "cytochrome complex assembly (16.7%) cell redox homeostasis (16.7%) DNA-templated DNA replication (1.8%)" "plasma membrane (16.1%) membrane (3%) cytoplasm (0.6%)" "protein-disulfide reductase activity (16.7%) DNA binding (2.4%) DNA-directed DNA polymerase activity (1.8%)" "IPR003834 (12.1%) IPR013766 (12.1%) IPR028250 (12.1%)" "Cytochrome C biogenesis protein, transmembrane domain (12.1%) Thioredoxin domain (12.1%) Thiol:disulfide interchange protein DsbD, N-terminal domain (12.1%)" FNPEYWNYAK root 1.17.4.1 (100%) ribonucleoside-diphosphate reductase (100%) "GO:0071897 (19.9%) GO:0009263 (19%)" GO:0016020 (0.1%) "GO:0004748 (20.4%) GO:0031419 (20.4%) GO:0005524 (18.9%)" "DNA biosynthetic process (19.9%) deoxyribonucleotide biosynthetic process (19%)" membrane (0.1%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (20.4%) cobalamin binding (20.4%) ATP binding (18.9%)" "IPR000788 (25.4%) IPR050862 (25.4%) IPR013344 (25.2%)" "Ribonucleotide reductase large subunit, C-terminal (25.4%) Ribonucleoside diphosphate reductase class-2 (25.4%) Ribonucleotide reductase, adenosylcobalamin-dependent (25.2%)" APVSGVLQYGDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019698 (50%) GO:0016829 (50%) D-galacturonate catabolic process (50%) lyase activity (50%) "IPR007392 (20%) IPR013974 (20%) IPR044144 (20%)" "D-galactarate/Altronate dehydratase, second domain (20%) SAF domain (20%) UxaA/GarD, SAF domain (20%)" TSVATYLNKEELLLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005840 (100%) ribosome (100%) LQLGEQEAQELVQNFFAEQEAK Pseudomonadati Bacteria Pseudomonadati 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" MAFLTAGMGGGTGTGAAPVLAR Pseudomonadati Bacteria Pseudomonadati "GO:0000917 (14.3%) GO:0043093 (14%) GO:0051258 (14%)" "GO:0005737 (14.4%) GO:0032153 (14.4%)" "GO:0003924 (14.4%) GO:0005525 (14.4%)" "division septum assembly (14.3%) FtsZ-dependent cytokinesis (14%) protein polymerization (14%)" "cytoplasm (14.4%) cell division site (14.4%)" "GTPase activity (14.4%) GTP binding (14.4%)" "IPR000158 (11.1%) IPR003008 (11.1%) IPR018316 (11.1%)" "Cell division protein FtsZ (11.1%) Tubulin/FtsZ, GTPase domain (11.1%) Tubulin/FtsZ, 2-layer sandwich domain (11.1%)" KYMGWALEYQVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella SVSNSYSNSYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLAFLDNLLKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0000160 (1.2%) "GO:0005524 (49.4%) GO:0016301 (49.4%)" phosphorelay signal transduction system (1.2%) "ATP binding (49.4%) kinase activity (49.4%)" "IPR002192 (30.3%) IPR051549 (30.3%) IPR013815 (28.8%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (30.3%) Phosphoenolpyruvate Utilizing Enzyme (30.3%) ATP-grasp fold, subdomain 1 (28.8%)" LVVVAAGVPSANLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.5.1.2 (100%) pyrroline-5-carboxylate reductase (100%) GO:0055129 (33.3%) GO:0005737 (33.3%) GO:0004735 (33.3%) L-proline biosynthetic process (33.3%) cytoplasm (33.3%) pyrroline-5-carboxylate reductase activity (33.3%) "IPR000304 (20.3%) IPR028939 (20.3%) IPR029036 (20.3%)" "Pyrroline-5-carboxylate reductase-like (20.3%) Pyrroline-5-carboxylate reductase, catalytic, N-terminal (20.3%) Pyrroline-5-carboxylate reductase, dimerisation domain (20.3%)" VYYGMHPDEQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.3%) IPR014729 (14.3%) IPR018223 (14.3%)" "Argininosuccinate synthase (14.3%) Rossmann-like alpha/beta/alpha sandwich fold (14.3%) Argininosuccinate synthase, conserved site (14.3%)" EKDPADAQVANFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FSGYVEADNGNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LGNNVTLHAGCVLGADGFGFAPGPEGYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.3.1.191 (95%) 2.3.1.- (5%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (95%) Transferring groups other than amino-acyl groups (5%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20%) IPR007691 (20%) IPR011004 (20%)" "Hexapeptide repeat (20%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20%) Trimeric LpxA-like superfamily (20%)" NDGLSEDALEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.5%) GO:0005737 (24.5%) "GO:0004821 (24.5%) GO:0005524 (24.5%) GO:0004812 (1.9%)" histidyl-tRNA aminoacylation (24.5%) cytoplasm (24.5%) "histidine-tRNA ligase activity (24.5%) ATP binding (24.5%) aminoacyl-tRNA ligase activity (1.9%)" "IPR041715 (13.2%) IPR045864 (13.2%) IPR004154 (12.3%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (13.2%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (13.2%) Anticodon-binding (12.3%)" LDSPNYLLVYLNLDGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR015171 (14.9%) IPR006047 (14.4%) IPR013783 (14.4%)" "Cyclomaltodextrinase, N-terminal (14.9%) Glycosyl hydrolase family 13, catalytic domain (14.4%) Immunoglobulin-like fold (14.4%)" LDYSALK root "1.11.1.21 (90%) 2.7.11.24 (1.1%) 1.14.13.225 (1%)" "catalase peroxidase (90%) mitogen-activated protein kinase (1.1%) F-actin monooxygenase (1%)" "GO:0042744 (10.5%) GO:0070301 (10.5%) GO:0015074 (1.6%)" "GO:0005829 (10.8%) GO:0030313 (2.1%) GO:0016020 (2%)" "GO:0046872 (10.8%) GO:0020037 (10.6%) GO:0004096 (10.5%)" "hydrogen peroxide catabolic process (10.5%) cellular response to hydrogen peroxide (10.5%) DNA integration (1.6%)" "cytosol (10.8%) cell envelope (2.1%) membrane (2%)" "metal ion binding (10.8%) heme binding (10.6%) catalase activity (10.5%)" "IPR000763 (9.9%) IPR010255 (9.9%) IPR002016 (9.9%)" "Catalase-peroxidase haem (9.9%) Haem peroxidase superfamily (9.9%) Haem peroxidase (9.9%)" PHVNLGTLGHVDHGK root "3.6.5.3 (99.9%) 2.7.1.25 (0%) 1.10.2.2 (0%)" "protein-synthesizing GTPase (99.9%) adenylyl-sulfate kinase (0%) Transferred entry: 7.1.1.8 (0%)" "GO:0070125 (4.8%) GO:0006414 (0%) GO:0009658 (0%)" "GO:0005829 (11.8%) GO:0005739 (4.8%) GO:0032045 (3.4%)" "GO:0003746 (18.5%) GO:0003924 (18.5%) GO:0005525 (18.5%)" "mitochondrial translational elongation (4.8%) translational elongation (0%) chloroplast organization (0%)" "cytosol (11.8%) mitochondrion (4.8%) guanyl-nucleotide exchange factor complex (3.4%)" "translation elongation factor activity (18.5%) GTPase activity (18.5%) GTP binding (18.5%)" "IPR000795 (8.8%) IPR027417 (8.8%) IPR050055 (8.6%)" "Translational (tr)-type GTP-binding domain (8.8%) P-loop containing nucleoside triphosphate hydrolase (8.8%) Elongation factor Tu GTPase (8.6%)" WYATTYR root 3.4.14.- (100%) Dipeptidyl-peptidases and tripeptidyl-peptidases (100%) "GO:0006508 (22.5%) GO:0043171 (22.5%)" "GO:0016020 (1.9%) GO:0005886 (1.3%)" "GO:0008239 (23.1%) GO:0070009 (23.1%) GO:0008270 (1.9%)" "proteolysis (22.5%) peptide catabolic process (22.5%)" "membrane (1.9%) plasma membrane (1.3%)" "dipeptidyl-peptidase activity (23.1%) serine-type aminopeptidase activity (23.1%) zinc ion binding (1.9%)" "IPR019500 (29.4%) IPR009003 (27.8%) IPR043504 (27%)" "Peptidase S46 (29.4%) Peptidase S1, PA clan (27.8%) Peptidase S1, PA clan, chymotrypsin-like fold (27%)" SNVDVLGATGTATAAPADLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) ASYGELGDDNLGDPFDSSRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" NLPTSLLEK root "2.4.2.9 (33.3%) 3.6.1.1 (33.3%) 6.1.1.20 (33.3%)" "uracil phosphoribosyltransferase (33.3%) inorganic diphosphatase (33.3%) phenylalanine--tRNA ligase (33.3%)" "GO:0000076 (9.9%) GO:0000278 (9.9%) GO:0030174 (9.9%)" "GO:0005634 (9.9%) GO:0009279 (2.5%) GO:0005737 (1.2%)" "GO:0003677 (9.9%) GO:0070182 (9.9%) GO:0043531 (4.9%)" "DNA replication checkpoint signaling (9.9%) mitotic cell cycle (9.9%) regulation of DNA-templated DNA replication initiation (9.9%)" "nucleus (9.9%) cell outer membrane (2.5%) cytoplasm (1.2%)" "DNA binding (9.9%) DNA polymerase binding (9.9%) ADP binding (4.9%)" "IPR041700 (25.6%) IPR014939 (6%) IPR032054 (6%)" "Outer membrane protein beta-barrel domain 3 (25.6%) CDT1 Geminin-binding domain-like (6%) DNA replication factor Cdt1, C-terminal (6%)" QFNNWLDNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LVEEMFDNLAPTYDTLNHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.163 (93.9%) 2.1.1.201 (6.1%)" "demethylmenaquinone methyltransferase (93.9%) 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase (6.1%)" "GO:0009234 (33.3%) GO:0032259 (33.3%)" GO:0043770 (33.3%) "menaquinone biosynthetic process (33.3%) methylation (33.3%)" demethylmenaquinone methyltransferase activity (33.3%) "IPR004033 (33.3%) IPR023576 (33.3%) IPR029063 (33.3%)" "UbiE/COQ5 methyltransferase (33.3%) UbiE/COQ5 methyltransferase, conserved site (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%)" VGTVDGLEYDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR003399 (50%) IPR052336 (50%)" "Mce/MlaD (50%) MlaD Inter-membrane Phospholipid Transporter (50%)" ELFDWAR root "2.3.1.31 (76.6%) 2.3.1.46 (7%) 3.5.1.28 (5.8%)" "homoserine O-acetyltransferase (76.6%) homoserine O-succinyltransferase (7%) N-acetylmuramoyl-L-alanine amidase (5.8%)" "GO:0019281 (19.5%) GO:0009253 (1.2%) GO:0009254 (1.2%)" "GO:0005737 (19.5%) GO:0005829 (1%) GO:0019867 (1%)" "GO:0008899 (19.5%) GO:0004414 (15.5%) GO:0005524 (2.2%)" "L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine (19.5%) peptidoglycan catabolic process (1.2%) peptidoglycan turnover (1.2%)" "cytoplasm (19.5%) cytosol (1%) outer membrane (1%)" "homoserine O-succinyltransferase activity (19.5%) homoserine O-acetyltransferase activity (15.5%) ATP binding (2.2%)" "IPR005697 (20.3%) IPR033752 (20.3%) IPR029062 (20.2%)" "Homoserine O-succinyltransferase MetA (20.3%) MetA family (20.3%) Class I glutamine amidotransferase-like (20.2%)" LAYMEYENRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021457 (100%) Protein of unknown function DUF3108 (100%) LLAEYPESYTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (17%) IPR004602 (17%) IPR041102 (17%)" "ABC transporter-like, ATP-binding domain (17%) UvrABC system subunit A (17%) UvrA, interaction domain (17%)" NQAYLDACMLPDESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (57.1%) "GO:0016787 (21.4%) GO:0016829 (21.4%)" carbohydrate metabolic process (57.1%) "hydrolase activity (21.4%) lyase activity (21.4%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" TLSYCESHDQALVGDK root 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (19.7%) GO:0005975 (0.4%)" GO:0005737 (20%) "GO:0003844 (20%) GO:0004553 (19.9%) GO:0043169 (19.9%)" "glycogen biosynthetic process (19.7%) carbohydrate metabolic process (0.4%)" cytoplasm (20%) "1,4-alpha-glucan branching enzyme activity (20%) hydrolase activity, hydrolyzing O-glycosyl compounds (19.9%) cation binding (19.9%)" "IPR006047 (12.7%) IPR004193 (12.6%) IPR006048 (12.6%)" "Glycosyl hydrolase family 13, catalytic domain (12.7%) Glycoside hydrolase, family 13, N-terminal (12.6%) Alpha-amylase/branching enzyme, C-terminal all beta (12.6%)" RVSEETENEEDDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.3%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.3%)" "IPR000241 (17.1%) IPR002052 (17.1%) IPR004114 (16.6%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.1%) DNA methylase, N-6 adenine-specific, conserved site (17.1%) THUMP domain (16.6%)" LKSEGDFEAAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.14.4 (100%) dipeptidyl-peptidase III (100%) "GO:0046872 (50%) GO:0016787 (49.5%) GO:0008239 (0.5%)" "metal ion binding (50%) hydrolase activity (49.5%) dipeptidyl-peptidase activity (0.5%)" IPR039461 (100%) Peptidase family M49 (100%) LKVTGSTLNVTLNEDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (27.5%) GO:0009279 (45%) GO:0015344 (27.5%) siderophore transmembrane transport (27.5%) cell outer membrane (45%) siderophore uptake transmembrane transporter activity (27.5%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" LDGLDDSEVAPATR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009166 (25%) "GO:0000166 (25%) GO:0016788 (25%) GO:0046872 (25%)" nucleotide catabolic process (25%) "nucleotide binding (25%) hydrolase activity, acting on ester bonds (25%) metal ion binding (25%)" "IPR004843 (25.5%) IPR006146 (25.5%) IPR006179 (25.5%)" "Calcineurin-like, phosphoesterase domain (25.5%) 5'-Nucleotidase, conserved site (25.5%) 5'-Nucleotidase/apyrase (25.5%)" QALSLLLTLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" EENEESQLQLAAFPYSDLQDDKVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.7%) IPR027304 (25.6%) IPR046357 (25.6%)" "Periplasmic chaperone PpiD (26.7%) Trigger factor/SurA domain superfamily (25.6%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.6%)" YKDCYTEGPWFMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.6%) "GO:0004553 (33.6%) GO:0030246 (32.8%)" carbohydrate metabolic process (33.6%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.6%) carbohydrate binding (32.8%)" "IPR006710 (12.9%) IPR005084 (12.6%) IPR006584 (12.6%)" "Glycoside hydrolase, family 43 (12.9%) Carbohydrate binding module family 6 (12.6%) Cellulose binding, type IV (12.6%)" ENMNCQELGLDTHLTPEYVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.99.17 (100%) phosphomethylpyrimidine synthase (100%) "GO:0009228 (16.7%) GO:0009229 (16.7%)" GO:0005829 (16.7%) "GO:0008270 (16.7%) GO:0051539 (16.7%) GO:0016830 (9.5%)" "thiamine biosynthetic process (16.7%) thiamine diphosphate biosynthetic process (16.7%)" cytosol (16.7%) "zinc ion binding (16.7%) 4 iron, 4 sulfur cluster binding (16.7%) carbon-carbon lyase activity (9.5%)" "IPR002817 (25%) IPR025747 (25%) IPR037509 (25%)" "Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B (25%) ThiC-associated domain (25%) Phosphomethylpyrimidine synthase (25%)" YLWLDSYAEVLGPDFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR030890 (100%) Substrate import-associated zinc metallohydrolase lipoprotein (100%) AFYEYHSLLMEPWDGPAALLFSDGR Pseudomonadati Bacteria Pseudomonadati "1.4.1.13 (99.4%) 1.4.1.14 (0.3%) 1.4.7.1 (0.3%)" "glutamate synthase (NADPH) (99.4%) glutamate synthase (NADH) (0.3%) glutamate synthase (ferredoxin) (0.3%)" "GO:0006537 (19.6%) GO:0019676 (19.5%)" "GO:0051538 (19.6%) GO:0046872 (19.4%) GO:0015930 (10.5%)" "glutamate biosynthetic process (19.6%) ammonia assimilation cycle (19.5%)" "3 iron, 4 sulfur cluster binding (19.6%) metal ion binding (19.4%) glutamate synthase activity (10.5%)" "IPR017932 (12.7%) IPR006982 (12.6%) IPR050711 (12.6%)" "Glutamine amidotransferase type 2 domain (12.7%) Glutamate synthase, central-N (12.6%) Electron transfer and nitrogen metabolism enzyme (12.6%)" GWAVTPGGTEMAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (33.3%) IPR038765 (33.3%) IPR044934 (33.3%)" "Peptidase C10, streptopain (33.3%) Papain-like cysteine peptidase superfamily (33.3%) Peptidase C10, streptopain superfmaily (33.3%)" QHGGELVFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004818 (16.7%) GO:0005524 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR000924 (9.9%) IPR001412 (9.9%) IPR004527 (9.9%)" "Glutamyl/glutaminyl-tRNA synthetase (9.9%) Aminoacyl-tRNA synthetase, class I, conserved site (9.9%) Glutamate-tRNA ligase, bacterial/mitochondrial (9.9%)" TTNLGLDFGLLDNR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (10%) GO:0009279 (80%) GO:0015344 (10%) siderophore transmembrane transport (10%) cell outer membrane (80%) siderophore uptake transmembrane transporter activity (10%) "IPR000531 (13.9%) IPR036942 (13.9%) IPR039426 (13.9%)" "TonB-dependent receptor-like, beta-barrel (13.9%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.9%) TonB-dependent receptor-like (13.9%)" LKPNAEMLCEGGLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.4%) GO:0005737 (19.4%) "GO:0004177 (20.4%) GO:0008270 (20.4%) GO:0008237 (19.4%)" proteolysis (20.4%) cytoplasm (19.4%) "aminopeptidase activity (20.4%) zinc ion binding (20.4%) metallopeptidase activity (19.4%)" "IPR001948 (51.3%) IPR023358 (48.7%)" "Peptidase M18 (51.3%) Peptidase M18, domain 2 (48.7%)" AHGETQLDGVSAFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.5%) IPR018165 (9.5%) IPR050058 (9.5%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.5%) Alanyl-tRNA synthetase, class IIc, core domain (9.5%) Alanine--tRNA ligase (9.5%)" DVHMLFVLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR003740 (25%) IPR015867 (25%) IPR019264 (25%)" "Uncharacterised membrane protein YitT (25%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25%) Domain of unknown function DUF2179 (25%)" GSWGQNGNVNLLNNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" PSASLLTEYGGVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (44.4%) GO:0009279 (55.6%) iron ion transport (44.4%) cell outer membrane (55.6%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MVFLVFK root "2.4.1.17 (75%) 2.4.99.28 (12.5%) 3.4.24.- (12.5%)" "glucuronosyltransferase (75%) peptidoglycan glycosyltransferase (12.5%) Metalloendopeptidases (12.5%)" "GO:0006508 (1.8%) GO:0006805 (1.8%) GO:0007156 (1.8%)" "GO:0005789 (19.6%) GO:0016020 (12.5%) GO:0005886 (8.9%)" "GO:0015020 (10.7%) GO:0004930 (3.6%) GO:0001972 (1.8%)" "proteolysis (1.8%) xenobiotic metabolic process (1.8%) homophilic cell-cell adhesion (1.8%)" "endoplasmic reticulum membrane (19.6%) membrane (12.5%) plasma membrane (8.9%)" "glucuronosyltransferase activity (10.7%) G protein-coupled receptor activity (3.6%) retinoic acid binding (1.8%)" "IPR002213 (7.6%) IPR035595 (7.6%) IPR050271 (7.6%)" "UDP-glucuronosyl/UDP-glucosyltransferase (7.6%) UDP-glycosyltransferase family, conserved site (7.6%) UDP-glycosyltransferase (7.6%)" LSLDSELNK root 2.7.13.3 (100%) histidine kinase (100%) "GO:0006281 (2%) GO:0006310 (2%) GO:0006887 (2%)" "GO:0009279 (42.9%) GO:0005886 (6.1%) GO:0000145 (2%)" "GO:0000155 (8.2%) GO:0005524 (4.1%) GO:0003676 (2%)" "DNA repair (2%) DNA recombination (2%) exocytosis (2%)" "cell outer membrane (42.9%) plasma membrane (6.1%) exocyst (2%)" "phosphorelay sensor kinase activity (8.2%) ATP binding (4.1%) nucleic acid binding (2%)" "IPR012910 (10.2%) IPR023997 (10.2%) IPR039426 (10.2%)" "TonB-dependent receptor, plug domain (10.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (10.2%) TonB-dependent receptor-like (10.2%)" PVLTLGTLSK root GO:0006572 (17.2%) GO:0016020 (24.1%) "GO:0047355 (24.1%) GO:0004838 (17.2%) GO:0030170 (17.2%)" L-tyrosine catabolic process (17.2%) membrane (24.1%) "CDP-glycerol glycerophosphotransferase activity (24.1%) L-tyrosine-2-oxoglutarate transaminase activity (17.2%) pyridoxal phosphate binding (17.2%)" "IPR007554 (13.5%) IPR043148 (12.9%) IPR051612 (12.9%)" "CDP-glycerol glycerophosphotransferase (13.5%) CDP-glycerol glycerophosphotransferase, C-terminal domain (12.9%) Teichoic Acid Biosynthesis Enzymes (12.9%)" FGLTSAELLTALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.7%) GO:0008295 (19.7%) GO:0033388 (19.7%)" "GO:0008792 (19.7%) GO:0046872 (19.7%) GO:0004497 (1.6%)" "L-arginine catabolic process (19.7%) spermidine biosynthetic process (19.7%) putrescine biosynthetic process from arginine (19.7%)" "arginine decarboxylase activity (19.7%) metal ion binding (19.7%) monooxygenase activity (1.6%)" "IPR002985 (11.4%) IPR022644 (11.4%) IPR022653 (11.4%)" "Arginine decarboxylase (11.4%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.4%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.4%)" GPVFANFVLADELNR root 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.1%) IPR050764 (25.1%) IPR027417 (25%)" "ATPase, AAA-3 (25.1%) CbbQ/NirQ/NorQ/GpvN (25.1%) P-loop containing nucleoside triphosphate hydrolase (25%)" TDFLDASQTADGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025178 (50%) IPR057436 (50%)" "Lnb, N-terminal periplasmic domain (50%) Lnb-like, transmembrane domain (50%)" GQLLMDGEELCDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.9%) IPR013486 (12.9%) IPR013693 (12.9%)" "Glycosyltransferase 2-like (12.9%) Sporulation stage II protein D, amidase enhancer LytB (12.9%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.9%)" LYDYGNGMNAGLNRPVLSQVNQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NPMMWFLDQGQPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (50%) "GO:0004553 (48.7%) GO:0008422 (1.3%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.7%) beta-glucosidase activity (1.3%)" "IPR001764 (12.7%) IPR002772 (12.7%) IPR026891 (12.7%)" "Glycoside hydrolase, family 3, N-terminal (12.7%) Glycoside hydrolase family 3 C-terminal domain (12.7%) Fibronectin type III-like domain (12.7%)" VMKEEEDSFLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR018164 (9.2%) IPR018165 (9.2%) IPR050058 (9.2%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.2%) Alanyl-tRNA synthetase, class IIc, core domain (9.2%) Alanine--tRNA ligase (9.2%)" LLEEEFKLPDYFLSDLSDTDER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0046873 (50%) membrane (50%) metal ion transmembrane transporter activity (50%) "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" LESQLFK root "3.1.3.11 (59.5%) 2.1.1.72 (4.8%) 6.1.1.7 (4.8%)" "fructose-bisphosphatase (59.5%) site-specific DNA-methyltransferase (adenine-specific) (4.8%) alanine--tRNA ligase (4.8%)" "GO:0006094 (3.3%) GO:0006310 (0.9%) GO:0006351 (0.7%)" "GO:0005856 (15.8%) GO:0005886 (7.2%) GO:0005634 (2.6%)" "GO:0003677 (9.9%) GO:0005254 (5.9%) GO:0042132 (3.3%)" "gluconeogenesis (3.3%) DNA recombination (0.9%) DNA-templated transcription (0.7%)" "cytoskeleton (15.8%) plasma membrane (7.2%) nucleus (2.6%)" "DNA binding (9.9%) chloride channel activity (5.9%) fructose 1,6-bisphosphate 1-phosphatase activity (3.3%)" "IPR000299 (6.1%) IPR001849 (6.1%) IPR011993 (6.1%)" "FERM domain (6.1%) Pleckstrin homology domain (6.1%) PH-like domain superfamily (6.1%)" MCLELLER root "5.1.3.11 (93.6%) 2.1.1.- (6.4%)" "cellobiose epimerase (93.6%) Methyltransferases (6.4%)" "GO:0005975 (38.4%) GO:0032259 (3.2%) GO:0000160 (0.5%)" "GO:0005737 (2.7%) GO:0005840 (2.2%) GO:0005634 (0.5%)" "GO:0047736 (39.5%) GO:0016279 (2.2%) GO:0008270 (1.1%)" "carbohydrate metabolic process (38.4%) methylation (3.2%) phosphorelay signal transduction system (0.5%)" "cytoplasm (2.7%) ribosome (2.2%) nucleus (0.5%)" "cellobiose epimerase activity (39.5%) protein-lysine N-methyltransferase activity (2.2%) zinc ion binding (1.1%)" "IPR010819 (21.8%) IPR028584 (21.5%) IPR008928 (20.9%)" "N-acylglucosamine 2-epimerase/Cellobiose 2-epimerase (21.8%) Cellobiose 2-epimerase (21.5%) Six-hairpin glycosidase superfamily (20.9%)" RAHSLAAQGGLNAAK root "1.3.5.1 (98.5%) 1.3.5.4 (1.4%) 1.3.99.1 (0.1%)" "succinate dehydrogenase (98.5%) Transferred entry: 1.3.5.1 (1.4%) Deleted entry (0.1%)" "GO:0009061 (18.7%) GO:0006108 (0%) GO:0006633 (0%)" "GO:0005886 (18.7%) GO:0005829 (0%) GO:0009317 (0%)" "GO:0009055 (18.7%) GO:0050660 (18.7%) GO:0000104 (14.5%)" "anaerobic respiration (18.7%) malate metabolic process (0%) fatty acid biosynthetic process (0%)" "plasma membrane (18.7%) cytosol (0%) acetyl-CoA carboxylase complex (0%)" "electron transfer activity (18.7%) flavin adenine dinucleotide binding (18.7%) succinate dehydrogenase activity (14.5%)" "IPR003953 (14.4%) IPR030664 (14.4%) IPR036188 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) FAD/NAD(P)-binding domain superfamily (14.4%)" FGGAYVPELLYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (50%) GO:0004834 (50%) cytoplasm (50%) tryptophan synthase activity (50%) "IPR023026 (20.5%) IPR036052 (20.5%) IPR001926 (20%)" "Tryptophan synthase beta chain/beta chain-like (20.5%) Tryptophan synthase beta chain-like, PALP domain superfamily (20.5%) Tryptophan synthase beta chain-like, PALP domain (20%)" GCSVDDLYYMVALTACQAQDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (60%) GO:0008959 (38.3%) GO:0016746 (1.7%)" "acetyltransferase activity (60%) phosphate acetyltransferase activity (38.3%) acyltransferase activity (1.7%)" "IPR002505 (16.9%) IPR050500 (16.9%) IPR004614 (16.6%)" "Phosphate acetyl/butaryl transferase (16.9%) Phosphate Acetyltransferase/Butyryltransferase (16.9%) Phosphate acetyltransferase (16.6%)" NCLVLLDNRPGLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LALDEQMMNELSNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20.2%) "GO:0048500 (19.2%) GO:0005786 (1%)" "GO:0003924 (20.2%) GO:0005525 (20.2%) GO:0008312 (18.2%)" SRP-dependent cotranslational protein targeting to membrane (20.2%) "signal recognition particle (19.2%) signal recognition particle, endoplasmic reticulum targeting (1%)" "GTPase activity (20.2%) GTP binding (20.2%) 7S RNA binding (18.2%)" "IPR000897 (11.6%) IPR003593 (11.6%) IPR022941 (11.6%)" "Signal recognition particle, SRP54 subunit, GTPase domain (11.6%) AAA+ ATPase domain (11.6%) Signal recognition particle, SRP54 subunit (11.6%)" VASLPTTR root "2.4.1.21 (89.7%) 3.4.19.12 (6.9%) 5.4.99.2 (3.4%)" "starch synthase (89.7%) ubiquitinyl hydrolase 1 (6.9%) methylmalonyl-CoA mutase (3.4%)" "GO:0006508 (3.6%) GO:0006633 (2.4%) GO:0009403 (2.4%)" "GO:0016020 (6%) GO:0005634 (1.2%) GO:0005737 (1.2%)" "GO:0016757 (31%) GO:0031177 (3.6%) GO:0003700 (2.4%)" "proteolysis (3.6%) fatty acid biosynthetic process (2.4%) toxin biosynthetic process (2.4%)" "membrane (6%) nucleus (1.2%) cytoplasm (1.2%)" "glycosyltransferase activity (31%) phosphopantetheine binding (3.6%) DNA-binding transcription factor activity (2.4%)" "IPR013534 (12.3%) IPR001680 (5.2%) IPR015943 (4.7%)" "Starch synthase, catalytic domain (12.3%) WD40 repeat (5.2%) WD40/YVTN repeat-like-containing domain superfamily (4.7%)" VLQEDLHDNPHNYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.51 (100%) prephenate dehydratase (100%) GO:0009094 (33.3%) GO:0005737 (33.3%) GO:0004664 (33.3%) L-phenylalanine biosynthetic process (33.3%) cytoplasm (33.3%) prephenate dehydratase activity (33.3%) "IPR001086 (26.3%) IPR002912 (26.3%) IPR045865 (26.3%)" "Prephenate dehydratase (26.3%) ACT domain (26.3%) ACT-like domain (26.3%)" YGSFDQLAENNNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20%) IPR008753 (20%) IPR018497 (20%)" "Peptidase M13 (20%) Peptidase M13, N-terminal domain (20%) Peptidase M13, C-terminal domain (20%)" LYNGNTVLDLDNLGVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.3%) IPR003593 (20.3%) IPR017871 (20.3%)" "ABC transporter-like, ATP-binding domain (20.3%) AAA+ ATPase domain (20.3%) ABC transporter-like, conserved site (20.3%)" EGWDNLDLFGWMGYPMQLK Bacteria Bacteria 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (27.9%) GO:0008654 (27.9%)" GO:0016020 (16.2%) GO:0004512 (27.9%) "inositol biosynthetic process (27.9%) phospholipid biosynthetic process (27.9%)" membrane (16.2%) inositol-3-phosphate synthase activity (27.9%) "IPR002587 (33.4%) IPR013021 (33.4%) IPR036291 (33.2%)" "Myo-inositol-1-phosphate synthase (33.4%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.4%) NAD(P)-binding domain superfamily (33.2%)" WFTLASK root "3.2.1.23 (92%) 3.5.2.6 (8%)" "beta-galactosidase (92%) beta-lactamase (8%)" "GO:0005990 (13.6%) GO:0070507 (3.6%) GO:0072393 (3.6%)" "GO:0009341 (13.6%) GO:0005794 (3.6%) GO:0005829 (3.6%)" "GO:0004565 (13.6%) GO:0030246 (13%) GO:0008093 (3.6%)" "lactose catabolic process (13.6%) regulation of microtubule cytoskeleton organization (3.6%) microtubule anchoring at microtubule organizing center (3.6%)" "beta-galactosidase complex (13.6%) Golgi apparatus (3.6%) cytosol (3.6%)" "beta-galactosidase activity (13.6%) carbohydrate binding (13%) cytoskeletal anchor activity (3.6%)" "IPR004199 (5.6%) IPR006102 (5.6%) IPR006103 (5.6%)" "Beta galactosidase small chain/ domain 5 (5.6%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (5.6%) Glycoside hydrolase family 2, catalytic domain (5.6%)" LYESMLQQADPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (25.5%) IPR053227 (25.5%) IPR027417 (24.5%)" "NadR/Ttd14, AAA domain (25.5%) TRPL channel trafficking regulator (25.5%) P-loop containing nucleoside triphosphate hydrolase (24.5%)" APMANTAFLSPELSNDFVTNLKNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) CPDAGLQLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016301 (51%) GO:0005524 (49%)" "kinase activity (51%) ATP binding (49%)" "IPR002192 (34.3%) IPR051549 (34.3%) IPR013815 (31.4%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (34.3%) Phosphoenolpyruvate Utilizing Enzyme (34.3%) ATP-grasp fold, subdomain 1 (31.4%)" VALVPQPDWHGDFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0051539 (33.7%) GO:0003824 (32.6%) GO:0005506 (32.6%)" "4 iron, 4 sulfur cluster binding (33.7%) catalytic activity (32.6%) iron ion binding (32.6%)" "IPR013704 (14.7%) IPR022946 (14.7%) IPR007197 (14.2%)" "UPF0313, N-terminal (14.7%) Uncharacterised protein family UPF0313 (14.7%) Radical SAM (14.2%)" WQPDVLVCQGWASAVVPFYVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.21 (100%) starch synthase (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR013534 (100%) Starch synthase, catalytic domain (100%) YNNEEVLLNEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.26.11 (100%) ribonuclease Z (100%) "GO:0008270 (50%) GO:0042781 (50%)" "zinc ion binding (50%) 3'-tRNA processing endoribonuclease activity (50%)" "IPR001279 (34.1%) IPR013471 (34.1%) IPR036866 (31.9%)" "Metallo-beta-lactamase (34.1%) Ribonuclease Z/BN (34.1%) Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (31.9%)" EALLHTNNNHWAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella AVLNELNASGAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" GVVLDDLGEPVLGATVQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.7%) IPR039426 (13.7%) IPR023996 (12.9%)" "TonB-dependent receptor, plug domain (13.7%) TonB-dependent receptor-like (13.7%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" LLGDFNK root "2.4.1.18 (32.1%) 7.1.2.2 (13.2%) 4.1.1.33 (7.5%)" "1,4-alpha-glucan branching enzyme (32.1%) H(+)-transporting two-sector ATPase (13.2%) diphosphomevalonate decarboxylase (7.5%)" "GO:0035332 (3.5%) GO:0038203 (2.5%) GO:0048172 (2.5%)" "GO:0016020 (6.1%) GO:0005886 (4.6%) GO:0030054 (3.5%)" "GO:0008168 (5.8%) GO:0016706 (5.8%) GO:0003844 (1.8%)" "positive regulation of hippo signaling (3.5%) TORC2 signaling (2.5%) regulation of short-term neuronal synaptic plasticity (2.5%)" "membrane (6.1%) plasma membrane (4.6%) cell junction (3.5%)" "methyltransferase activity (5.8%) 2-oxoglutarate-dependent dioxygenase activity (5.8%) 1,4-alpha-glucan branching enzyme activity (1.8%)" "IPR036691 (7.7%) IPR000477 (6.1%) IPR043502 (5.7%)" "Endonuclease/exonuclease/phosphatase superfamily (7.7%) Reverse transcriptase domain (6.1%) DNA/RNA polymerase superfamily (5.7%)" EQALLMMADTVEAASR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (88.1%) GO:0016787 (11.9%) membrane (88.1%) hydrolase activity (11.9%) "IPR003607 (16.7%) IPR006674 (16.7%) IPR006675 (16.7%)" "HD/PDEase domain (16.7%) HD domain (16.7%) HDIG domain (16.7%)" NFTYATDLEEEQLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.2%) IPR011659 (14.2%) IPR012393 (14.2%)" "Tail specific protease (14.2%) WD40-like beta-propeller (14.2%) Tricorn protease (14.2%)" WELNGAQLVLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.1.103 (100%) teichoic acid D-alanine hydrolase (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR001466 (34%) IPR050491 (34%) IPR012338 (32%)" "Beta-lactamase-related (34%) Beta-lactamase AmpC-like (34%) Beta-lactamase/transpeptidase-like (32%)" VDEDGNGAEAGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.21.107 (80%) 3.4.21.- (20%)" "peptidase Do (80%) Serine endopeptidases (20%)" GO:0006508 (48.9%) GO:0016020 (2.1%) GO:0004252 (48.9%) proteolysis (48.9%) membrane (2.1%) serine-type endopeptidase activity (48.9%) "IPR001478 (17.6%) IPR025926 (17.6%) IPR001940 (16.8%)" "PDZ domain (17.6%) PDZ-like domain (17.6%) Peptidase S1C (16.8%)" WKQPGDLTDLPR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (2.8%) GO:0009279 (97.2%) iron ion transport (2.8%) cell outer membrane (97.2%) "IPR012910 (12.8%) IPR023996 (12.8%) IPR023997 (12.8%)" "TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.8%)" NGMLETAAGTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0004553 (85.7%) GO:0016787 (14.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (85.7%) hydrolase activity (14.3%)" "IPR008979 (35%) IPR053161 (35%) IPR054593 (30%)" "Galactose-binding-like domain superfamily (35%) Ulvan-degrading glycoside hydrolase (35%) Beta-mannosidase-like, galactose-binding domain-like (30%)" MFLQNLTPGLLQTQGTNLGEALDLASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR002035 (25.7%) IPR024163 (25.7%) IPR050768 (25.7%)" "von Willebrand factor, type A (25.7%) Aerotolerance regulator, N-terminal (25.7%) UPF0353/GerABKA protein families (25.7%)" LVLNQGLGDATQDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" RADGNPNTFAFLGSPELTVALTLAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.6%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.6%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" TSFTGSPSNEQYAFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" WDAQPDAEAAR Pseudomonadati Bacteria Pseudomonadati GO:0009166 (48.1%) "GO:0016787 (48.1%) GO:0016616 (3.7%)" nucleotide catabolic process (48.1%) "hydrolase activity (48.1%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (3.7%)" "IPR006179 (31%) IPR008334 (31%) IPR036907 (28.6%)" "5'-Nucleotidase/apyrase (31%) 5'-Nucleotidase, C-terminal (31%) 5'-Nucleotidase, C-terminal domain superfamily (28.6%)" KVNDLFAEWAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FCMAGSGDMMDQMLYLAAER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.-.- (66.7%) 2.4.1.11 (22.2%) 2.4.1.21 (11.1%)" "Glycosyltransferases (66.7%) glycogen(starch) synthase (22.2%) starch synthase (11.1%)" "GO:0016757 (60%) GO:0016758 (32.5%) GO:0004373 (5%)" "glycosyltransferase activity (60%) hexosyltransferase activity (32.5%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (5%)" "IPR001296 (34.5%) IPR028098 (33.6%) IPR050194 (31%)" "Glycosyl transferase, family 1 (34.5%) Glycosyltransferase subfamily 4-like, N-terminal domain (33.6%) Glycosyltransferase group 1 (31%)" LNELLTQLLEFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23.4%) "GO:0000155 (23.4%) GO:0003700 (23.4%) GO:0043565 (23.4%)" membrane (23.4%) "phosphorelay sensor kinase activity (23.4%) DNA-binding transcription factor activity (23.4%) sequence-specific DNA binding (23.4%)" "IPR001789 (7%) IPR003594 (7%) IPR003661 (7%)" "Signal transduction response regulator, receiver domain (7%) Histidine kinase/HSP90-like ATPase domain (7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7%)" FDTQSYQYAETPAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.2%) "GO:0000155 (26.7%) GO:0003700 (24.2%) GO:0043565 (24.2%)" membrane (24.2%) "phosphorelay sensor kinase activity (26.7%) DNA-binding transcription factor activity (24.2%) sequence-specific DNA binding (24.2%)" "IPR011110 (16.6%) IPR015943 (15.6%) IPR011123 (14.1%)" "Two component regulator propeller (16.6%) WD40/YVTN repeat-like-containing domain superfamily (15.6%) Two component regulator three Y (14.1%)" FDDLYVAVDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (51.2%) IPR027417 (48.8%)" "Tetraacyldisaccharide 4'-kinase (51.2%) P-loop containing nucleoside triphosphate hydrolase (48.8%)" QLAYLPMADTTWMTHLTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" DLESVLSLK root 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.5%) GO:0006164 (0.5%)" "GO:0005737 (20%) GO:0005739 (0.2%) GO:0016020 (0.2%)" "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (19.5%)" "'de novo' IMP biosynthetic process (19.5%) purine nucleotide biosynthetic process (0.5%)" "cytoplasm (20%) mitochondrion (0.2%) membrane (0.2%)" "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (19.5%)" "IPR036921 (11.1%) IPR040707 (11.1%) IPR041609 (11.1%)" "PurM-like, N-terminal domain superfamily (11.1%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.1%) Phosphoribosylformylglycinamidine synthase, linker domain (11.1%)" APMPWSLLMVTGGVSPDADNLASWLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" GO:0016829 (100%) lyase activity (100%) "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" AAAMFTGNTLDLGNAVQNFWQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FLPMVLHMNVPLLSLTGNPDSLLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (25%) GO:1901135 (25%)" "GO:0019146 (25%) GO:0097367 (25%)" "carbohydrate metabolic process (25%) carbohydrate derivative metabolic process (25%)" "arabinose-5-phosphate isomerase activity (25%) carbohydrate derivative binding (25%)" "IPR000644 (14.8%) IPR001347 (14.8%) IPR004800 (14.8%)" "CBS domain (14.8%) SIS domain (14.8%) Phosphosugar isomerase, KdsD/KpsF-type (14.8%)" TDTPTSGTLEFVADESLRPLLDEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" LLQTSLGK root "1.6.5.9 (90.2%) 1.6.5.- (3.7%) 2.3.2.26 (2.4%)" "NADH:ubiquinone reductase (non-electrogenic) (90.2%) With a quinone or similar compound as acceptor (3.7%) HECT-type E3 ubiquitin transferase (2.4%)" "GO:0006355 (1.3%) GO:0000209 (0.9%) GO:0006260 (0.9%)" "GO:0005634 (7.3%) GO:0016020 (1.7%) GO:0005737 (1.3%)" "GO:0003954 (29.1%) GO:0004402 (5.1%) GO:0005524 (3.8%)" "regulation of DNA-templated transcription (1.3%) protein polyubiquitination (0.9%) DNA replication (0.9%)" "nucleus (7.3%) membrane (1.7%) cytoplasm (1.3%)" "NADH dehydrogenase activity (29.1%) histone acetyltransferase activity (5.1%) ATP binding (3.8%)" "IPR023753 (12.6%) IPR045024 (12.6%) IPR036188 (12.3%)" "FAD/NAD(P)-binding domain (12.6%) Alternative NADH dehydrogenase (12.6%) FAD/NAD(P)-binding domain superfamily (12.3%)" LRDELLR root "4.1.99.22 (17.4%) 3.6.4.13 (9.4%) 3.6.5.3 (3.9%)" "GTP 3',8-cyclase (17.4%) RNA helicase (9.4%) protein-synthesizing GTPase (3.9%)" "GO:0051693 (3.2%) GO:0006777 (1.1%) GO:0032259 (0.9%)" "GO:0016020 (4.1%) GO:0005829 (3.1%) GO:0008091 (2.7%)" "GO:0005524 (3.7%) GO:0005543 (2.8%) GO:0005200 (2.7%)" "actin filament capping (3.2%) Mo-molybdopterin cofactor biosynthetic process (1.1%) methylation (0.9%)" "membrane (4.1%) cytosol (3.1%) spectrin (2.7%)" "ATP binding (3.7%) phospholipid binding (2.8%) structural constituent of cytoskeleton (2.7%)" "IPR027417 (2.8%) IPR018159 (2.7%) IPR002017 (2.6%)" "P-loop containing nucleoside triphosphate hydrolase (2.8%) Spectrin/alpha-actinin (2.7%) Spectrin repeat (2.6%)" VMLGTLGWPGNFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" MSLLEALAQCGDLTLYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (46.7%) GO:0015159 (53.3%) membrane (46.7%) polysaccharide transmembrane transporter activity (53.3%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" LLDQEVGLESCQPELAELEKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) VDLSEEQLDEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) TSVNQNMGHNWQLTWTNTLSYDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" KLHLMGLTSTGGVHSSLDHLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20.3%) IPR006124 (20.3%) IPR011258 (20.3%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20.3%) Metalloenzyme (20.3%) BPG-independent PGAM, N-terminal (20.3%)" KEELVTAVK root "GO:0006352 (9.1%) GO:0007005 (4.5%)" "GO:0016020 (54.5%) GO:0005737 (9.1%) GO:0005741 (4.5%)" "GO:0003677 (9.1%) GO:0016987 (9.1%)" "DNA-templated transcription initiation (9.1%) mitochondrion organization (4.5%)" "membrane (54.5%) cytoplasm (9.1%) mitochondrial outer membrane (4.5%)" "DNA binding (9.1%) sigma factor activity (9.1%)" "IPR000943 (6.7%) IPR007127 (6.7%) IPR007624 (6.7%)" "RNA polymerase sigma-70 (6.7%) RNA polymerase sigma factor 70, region 1.1 (6.7%) RNA polymerase sigma-70 region 3 (6.7%)" EVLLDDLFK root 2.7.4.3 (100%) adenylate kinase (100%) "GO:0000002 (10%) GO:0006172 (10%) GO:0046033 (10%)" "GO:0005743 (10%) GO:0005758 (10%) GO:0005829 (10%)" "GO:0003723 (10%) GO:0004017 (10%) GO:0005524 (10%)" "obsolete mitochondrial genome maintenance (10%) ADP biosynthetic process (10%) AMP metabolic process (10%)" "mitochondrial inner membrane (10%) mitochondrial intermembrane space (10%) cytosol (10%)" "RNA binding (10%) AMP kinase activity (10%) ATP binding (10%)" "IPR000504 (7.7%) IPR000850 (7.7%) IPR006259 (7.7%)" "RNA recognition motif domain (7.7%) Adenylate kinase/UMP-CMP kinase (7.7%) Adenylate kinase subfamily (7.7%)" KQLSSLYASASLGYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (11.4%) GO:0009279 (88.6%) iron ion transport (11.4%) cell outer membrane (88.6%) "IPR012910 (14.2%) IPR023996 (14.2%) IPR023997 (14.2%)" "TonB-dependent receptor, plug domain (14.2%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.2%)" DAASAALYGAQAGNGVVLLTTK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006826 (3.5%) GO:0009279 (96.5%) iron ion transport (3.5%) cell outer membrane (96.5%) "IPR008969 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "Carboxypeptidase-like, regulatory domain superfamily (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" GLMAPTAQEVEDYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025393 (51.9%) IPR029044 (48.1%)" "Domain of unknown function DUF4301 (51.9%) Nucleotide-diphospho-sugar transferases (48.1%)" DAVPGTDFMPLQVDYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.1%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.1%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR001247 (8%) IPR012162 (8%) IPR015847 (8%)" "Exoribonuclease, phosphorolytic domain 1 (8%) Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 2 (8%)" KLAPLAAAAK Bacteria Bacteria "2.6.1.- (55.6%) 2.6.1.1 (44.4%)" "Transaminases (55.6%) aspartate transaminase (44.4%)" GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (31.4%) GO:0004069 (1.9%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (31.4%) L-aspartate:2-oxoglutarate aminotransferase activity (1.9%)" "IPR004839 (20.2%) IPR050596 (20.2%) IPR015421 (19.7%)" "Aminotransferase, class I/classII, large domain (20.2%) Aspartate/prephenate aminotransferase-like (20.2%) Pyridoxal phosphate-dependent transferase, major domain (19.7%)" ALAPNLYK root "6.3.2.1 (88%) 2.4.1.21 (12%)" "pantoate--beta-alanine ligase (AMP-forming) (88%) starch synthase (12%)" "GO:0015940 (12.1%) GO:0006914 (5.2%) GO:0007030 (5.2%)" "GO:0005829 (12.1%) GO:0005789 (5.2%) GO:0012507 (5.2%)" "GO:0004592 (12.1%) GO:0005524 (12.1%) GO:0004373 (1.1%)" "pantothenate biosynthetic process (12.1%) autophagy (5.2%) Golgi organization (5.2%)" "cytosol (12.1%) endoplasmic reticulum membrane (5.2%) ER to Golgi transport vesicle membrane (5.2%)" "pantoate-beta-alanine ligase activity (12.1%) ATP binding (12.1%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (1.1%)" "IPR003721 (19.4%) IPR014729 (19.4%) IPR042176 (19.4%)" "Pantoate-beta-alanine ligase (19.4%) Rossmann-like alpha/beta/alpha sandwich fold (19.4%) Pantoate-beta-alanine ligase, C-terminal domain (19.4%)" SLNLGEGYNLYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (25%) GO:0005576 (25%) "GO:0033939 (25%) GO:0046559 (25%)" xylan catabolic process (25%) extracellular region (25%) "xylan alpha-1,2-glucuronosidase activity (25%) alpha-glucuronidase activity (25%)" "IPR011099 (20.5%) IPR011100 (20.5%) IPR017853 (19.7%)" "Glycosyl hydrolase family 67, C-terminal (20.5%) Glycosyl hydrolase family 67, catalytic domain (20.5%) Glycoside hydrolase superfamily (19.7%)" GLYYLADTLLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (17.8%) "GO:0016746 (17.8%) GO:0046872 (17.8%) GO:0051287 (17.8%)" malate metabolic process (17.8%) "acyltransferase activity (17.8%) metal ion binding (17.8%) NAD binding (17.8%)" "IPR002505 (9%) IPR012188 (9%) IPR012301 (9%)" "Phosphate acetyl/butaryl transferase (9%) NAD(P)-dependent malic enzyme (9%) Malic enzyme, N-terminal domain (9%)" LSEYNTLEELPAEVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.8%) 6.3.4.16 (49.2%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.8%) carbamoyl-phosphate synthase (ammonia) (49.2%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.2%) IPR005480 (10.2%) IPR006275 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.2%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.2%) Carbamoyl-phosphate synthase, large subunit (10.2%)" FSMFNLK root "3.1.21.- (50%) 6.1.1.20 (50%)" "Endodeoxyribonucleases producing 5'-phosphomonoesters (50%) phenylalanine--tRNA ligase (50%)" "GO:0006432 (4%) GO:0007059 (4%) GO:0016192 (4%)" "GO:0005886 (16%) GO:0016020 (8%) GO:0000139 (4%)" "GO:0005085 (8%) GO:0005524 (8%) GO:0000049 (4%)" "phenylalanyl-tRNA aminoacylation (4%) chromosome segregation (4%) vesicle-mediated transport (4%)" "plasma membrane (16%) membrane (8%) Golgi membrane (4%)" "guanyl-nucleotide exchange factor activity (8%) ATP binding (8%) tRNA binding (4%)" "IPR024361 (15.7%) IPR013783 (15.2%) IPR032675 (15.2%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (15.7%) Immunoglobulin-like fold (15.2%) Leucine-rich repeat domain superfamily (15.2%)" ELLFAVR root "1.1.5.3 (29%) 2.7.13.3 (24.6%) 4.2.99.18 (8.7%)" "glycerol-3-phosphate dehydrogenase (29%) histidine kinase (24.6%) DNA-(apurinic or apyrimidinic site) lyase (8.7%)" "GO:0006633 (2.7%) GO:0044550 (2.6%) GO:0006071 (2.2%)" "GO:0009279 (19%) GO:0005886 (5.7%) GO:0016020 (3.4%)" "GO:0005524 (3.6%) GO:0016491 (2.7%) GO:0004312 (2.6%)" "fatty acid biosynthetic process (2.7%) secondary metabolite biosynthetic process (2.6%) glycerol metabolic process (2.2%)" "cell outer membrane (19%) plasma membrane (5.7%) membrane (3.4%)" "ATP binding (3.6%) oxidoreductase activity (2.7%) fatty acid synthase activity (2.6%)" "IPR011990 (8.8%) IPR012944 (8.6%) IPR033985 (8.1%)" "Tetratricopeptide-like helical domain superfamily (8.8%) RagB/SusD domain (8.6%) SusD-like, N-terminal (8.1%)" LEESYGEDGYLSAVMGTAFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" NLEYLGLK root "2.7.2.1 (79.3%) 3.2.2.6 (6.9%) 2.7.11.1 (3.4%)" "acetate kinase (79.3%) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (6.9%) non-specific serine/threonine protein kinase (3.4%)" "GO:0006083 (11.2%) GO:0006085 (10.3%) GO:0000398 (4.7%)" "GO:0005737 (11.7%) GO:0016020 (1.9%) GO:0005576 (1.4%)" "GO:0005524 (13.6%) GO:0008776 (11.2%) GO:0000287 (10.3%)" "acetate metabolic process (11.2%) acetyl-CoA biosynthetic process (10.3%) mRNA splicing, via spliceosome (4.7%)" "cytoplasm (11.7%) membrane (1.9%) extracellular region (1.4%)" "ATP binding (13.6%) acetate kinase activity (11.2%) magnesium ion binding (10.3%)" "IPR000890 (11%) IPR004372 (11%) IPR023865 (11%)" "Aliphatic acid kinase, short-chain (11%) Acetate/propionate kinase (11%) Aliphatic acid kinase, short-chain, conserved site (11%)" ELLGAEFK root "4.1.1.23 (75%) 2.7.13.3 (25%)" "orotidine-5'-phosphate decarboxylase (75%) histidine kinase (25%)" "GO:0006412 (15.7%) GO:0006207 (0.5%) GO:0044205 (0.5%)" "GO:0005829 (16.1%) GO:0015935 (15.7%) GO:0005737 (1.6%)" "GO:0003735 (15.7%) GO:0019843 (15.7%) GO:0000049 (15.2%)" "translation (15.7%) 'de novo' pyrimidine nucleobase biosynthetic process (0.5%) 'de novo' UMP biosynthetic process (0.5%)" "cytosol (16.1%) small ribosomal subunit (15.7%) cytoplasm (1.6%)" "structural constituent of ribosome (15.7%) rRNA binding (15.7%) tRNA binding (15.2%)" "IPR001892 (15.1%) IPR010979 (15.1%) IPR018269 (15.1%)" "Small ribosomal subunit protein uS13 (15.1%) Small ribosomal subunit protein uS13-like, H2TH (15.1%) Small ribosomal subunit protein uS13, conserved site (15.1%)" EVLVNLGYK Bacteria Bacteria "6.3.2.8 (71.9%) 1.17.7.4 (25%) 2.7.7.8 (3.1%)" "UDP-N-acetylmuramate--L-alanine ligase (71.9%) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (25%) polyribonucleotide nucleotidyltransferase (3.1%)" "GO:0006412 (16.1%) GO:0008360 (3.3%) GO:0009252 (3.3%)" "GO:0022627 (15.9%) GO:0005737 (4.5%) GO:0005840 (0.6%)" "GO:0003729 (17.3%) GO:0003735 (16.3%) GO:0005524 (3.3%)" "translation (16.1%) regulation of cell shape (3.3%) peptidoglycan biosynthetic process (3.3%)" "cytosolic small ribosomal subunit (15.9%) cytoplasm (4.5%) ribosome (0.6%)" "mRNA binding (17.3%) structural constituent of ribosome (16.3%) ATP binding (3.3%)" "IPR003029 (18.3%) IPR012340 (18.3%) IPR035104 (18.3%)" "S1 domain (18.3%) Nucleic acid-binding, OB-fold (18.3%) Ribosomal protein S1-like (18.3%)" CNHSHLLYTECCPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR040572 (100%) Thaumarchaeal output domain 1 (100%) QFTDALPLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GLYYLADTLLNRHPDEDVLLDVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006108 (16.7%) "GO:0004470 (16.7%) GO:0016616 (16.7%) GO:0016746 (16.7%)" malate metabolic process (16.7%) "malic enzyme activity (16.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.7%) acyltransferase activity (16.7%)" "IPR002505 (9.1%) IPR012188 (9.1%) IPR012301 (9.1%)" "Phosphate acetyl/butaryl transferase (9.1%) NAD(P)-dependent malic enzyme (9.1%) Malic enzyme, N-terminal domain (9.1%)" QPNSTPEALWALVEADLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" AYWQEQVFENVLSFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" ADLEEETVDHVLSVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (20%) GO:0031564 (20%)" GO:0005829 (20%) "GO:0003700 (20%) GO:0003723 (20%)" "DNA-templated transcription termination (20%) transcription antitermination (20%)" cytosol (20%) "DNA-binding transcription factor activity (20%) RNA binding (20%)" "IPR003029 (12.2%) IPR010213 (12.2%) IPR013735 (12.2%)" "S1 domain (12.2%) Transcription factor NusA (12.2%) Transcription factor NusA, N-terminal (12.2%)" TQPFTLNVEKGDGTSDNETSDFSNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR013105 (25.6%) IPR019734 (25.6%) IPR025738 (25.6%)" "Tetratricopeptide repeat 2 (25.6%) Tetratricopeptide repeat (25.6%) Aerotolerance-related protein BatD (25.6%)" VTLTDMQEGDEAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (50%) GO:0016149 (50%) cytoplasm (50%) translation release factor activity, codon specific (50%) "IPR000352 (25.3%) IPR004374 (25.3%) IPR005139 (25.3%)" "Peptide chain release factor class I (25.3%) Peptide chain release factor 2 (25.3%) Peptide chain release factor (25.3%)" ADEVYDKLLVELEAVLDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YKDVTGDGLVSASDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" PNLDGGLLGGASLK root "5.3.1.1 (99.4%) 2.7.2.3 (0.6%)" "triose-phosphate isomerase (99.4%) phosphoglycerate kinase (0.6%)" "GO:0006094 (14.3%) GO:0006096 (14.3%) GO:0019563 (14.2%)" "GO:0005829 (14.3%) GO:0016020 (7.1%)" "GO:0004807 (14.3%) GO:0004618 (0.1%) GO:0005524 (0.1%)" "gluconeogenesis (14.3%) glycolytic process (14.3%) glycerol catabolic process (14.2%)" "cytosol (14.3%) membrane (7.1%)" "triose-phosphate isomerase activity (14.3%) phosphoglycerate kinase activity (0.1%) ATP binding (0.1%)" "IPR000652 (18.3%) IPR020861 (18.3%) IPR022896 (18.1%)" "Triosephosphate isomerase (18.3%) Triosephosphate isomerase, active site (18.3%) Triosephosphate isomerase, bacterial/eukaryotic (18.1%)" RYGVNTEFLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" LEQLEPMELAQYYTNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.16 (100%) cysteine--tRNA ligase (100%) GO:0006423 (20%) GO:0005829 (20%) "GO:0004817 (20%) GO:0005524 (20%) GO:0008270 (19.6%)" cysteinyl-tRNA aminoacylation (20%) cytosol (20%) "cysteine-tRNA ligase activity (20%) ATP binding (20%) zinc ion binding (19.6%)" "IPR009080 (14.4%) IPR014729 (14.4%) IPR015273 (14.4%)" "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (14.4%) Rossmann-like alpha/beta/alpha sandwich fold (14.4%) Cysteinyl-tRNA synthetase, class Ia, DALR (14.4%)" NLLDWSK root "2.7.11.1 (54.9%) 2.7.13.3 (17.6%) 1.15.1.1 (7.8%)" "non-specific serine/threonine protein kinase (54.9%) histidine kinase (17.6%) superoxide dismutase (7.8%)" "GO:0031145 (8%) GO:1905786 (8%) GO:0051301 (5.7%)" "GO:0005680 (8%) GO:0000139 (3.9%) GO:0005886 (3.1%)" "GO:0010997 (8%) GO:1990757 (8%) GO:0016757 (3.6%)" "anaphase-promoting complex-dependent catabolic process (8%) positive regulation of anaphase-promoting complex-dependent catabolic process (8%) cell division (5.7%)" "anaphase-promoting complex (8%) Golgi membrane (3.9%) plasma membrane (3.1%)" "anaphase-promoting complex binding (8%) ubiquitin ligase activator activity (8%) glycosyltransferase activity (3.6%)" "IPR015943 (5.5%) IPR033010 (5.3%) IPR001680 (5.2%)" "WD40/YVTN repeat-like-containing domain superfamily (5.5%) WD repeat Cdc20/Fizzy (5.3%) WD40 repeat (5.2%)" SGQQLLGTPPMEQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.3.1.191 (96.7%) 2.3.1.- (3.3%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (96.7%) Transferring groups other than amino-acyl groups (3.3%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20%) IPR007691 (20%) IPR011004 (20%)" "Hexapeptide repeat (20%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20%) Trimeric LpxA-like superfamily (20%)" FLFGSLELTSLHTEDTEESLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" ENPDGLLLSFGGQTALNCGVELYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.9%) GO:0006221 (12.8%) GO:0006526 (12.8%)" GO:0005737 (14.9%) "GO:0004088 (14.9%) GO:0005524 (14.9%) GO:0046872 (14.9%)" "glutamine metabolic process (14.9%) pyrimidine nucleotide biosynthetic process (12.8%) L-arginine biosynthetic process (12.8%)" cytoplasm (14.9%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.9%) ATP binding (14.9%) metal ion binding (14.9%)" "IPR005479 (12.5%) IPR005480 (12.5%) IPR011761 (12.5%)" "Carbamoyl phosphate synthase, ATP-binding domain (12.5%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (12.5%) ATP-grasp fold (12.5%)" ADALAEFK root "7.1.2.2 (48.6%) 6.1.1.3 (22.4%) 3.6.1.9 (19.6%)" "H(+)-transporting two-sector ATPase (48.6%) threonine--tRNA ligase (22.4%) nucleotide diphosphatase (19.6%)" "GO:0006435 (4.4%) GO:0009117 (4%) GO:0051301 (0.8%)" "GO:0005886 (10.7%) GO:0045259 (9.9%) GO:0005737 (8.6%)" "GO:0005524 (14.5%) GO:0043531 (9.9%) GO:0046933 (9.9%)" "threonyl-tRNA aminoacylation (4.4%) nucleotide metabolic process (4%) cell division (0.8%)" "plasma membrane (10.7%) proton-transporting ATP synthase complex (9.9%) cytoplasm (8.6%)" "ATP binding (14.5%) ADP binding (9.9%) proton-transporting ATP synthase activity, rotational mechanism (9.9%)" "IPR000194 (5.5%) IPR000793 (5.5%) IPR004100 (5.5%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (5.5%) ATP synthase, alpha subunit, C-terminal (5.5%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (5.5%)" GDGLHFLAESYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (50%) GO:0016788 (47.2%) GO:0016787 (2.8%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (47.2%) hydrolase activity (2.8%)" "IPR000801 (17.1%) IPR005181 (17.1%) IPR050583 (17.1%)" "Esterase-like (17.1%) Sialate O-acetylesterase domain (17.1%) Mycobacterial A85 antigen (17.1%)" DEMLAHYGVQSER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" YLVELGR root "3.1.4.52 (33%) 2.7.2.1 (15.5%) 1.1.1.169 (7.8%)" "cyclic-guanylate-specific phosphodiesterase (33%) acetate kinase (15.5%) 2-dehydropantoate 2-reductase (7.8%)" "GO:0006352 (10.1%) GO:0006606 (2%) GO:0006083 (1%)" "GO:0016020 (4.7%) GO:0005886 (3.6%) GO:0005737 (3.2%)" "GO:0003677 (12.4%) GO:0016987 (10.1%) GO:0071111 (3%)" "DNA-templated transcription initiation (10.1%) protein import into nucleus (2%) acetate metabolic process (1%)" "membrane (4.7%) plasma membrane (3.6%) cytoplasm (3.2%)" "DNA binding (12.4%) sigma factor activity (10.1%) cyclic-guanylate-specific phosphodiesterase activity (3%)" "IPR036388 (5%) IPR007627 (4.7%) IPR009042 (4.7%)" "Winged helix-like DNA-binding domain superfamily (5%) RNA polymerase sigma-70 region 2 (4.7%) RNA polymerase sigma-70 region 1.2 (4.7%)" EYVGLLAHQLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (95.8%) GO:0016787 (4.2%) membrane (95.8%) hydrolase activity (4.2%) "IPR003607 (16.7%) IPR006674 (16.7%) IPR006675 (16.7%)" "HD/PDEase domain (16.7%) HD domain (16.7%) HDIG domain (16.7%)" KVSLETLGTNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.5%) GO:0005829 (16.5%) "GO:0003677 (16.5%) GO:0004527 (16.5%) GO:0005524 (16.5%)" recombinational repair (16.5%) cytosol (16.5%) "DNA binding (16.5%) exonuclease activity (16.5%) ATP binding (16.5%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" FVANLKAALNANDFAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0017038 (46.7%) "GO:0005886 (46.7%) GO:0016020 (6.7%)" protein import (46.7%) "plasma membrane (46.7%) membrane (6.7%)" "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" MDLLKVAEEAFATGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (33.2%) "GO:0022625 (32.8%) GO:0005840 (0.4%) GO:1990904 (0.4%)" GO:0003735 (33.2%) translation (33.2%) "cytosolic large ribosomal subunit (32.8%) ribosome (0.4%) ribonucleoprotein complex (0.4%)" structural constituent of ribosome (33.2%) "IPR001857 (25.2%) IPR008991 (25.2%) IPR038657 (24.9%)" "Large ribosomal subunit protein bL19 (25.2%) Translation protein SH3-like domain superfamily (25.2%) Large ribosomal subunit protein bL19 superfamily (24.9%)" YVVAVGGCALSGGPFKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0009060 (11.5%) GO:0015990 (11.5%)" "GO:0045271 (11.5%) GO:0005886 (10.6%)" "GO:0008137 (11.5%) GO:0005506 (10.6%) GO:0048038 (10.6%)" "aerobic respiration (11.5%) electron transport coupled proton transport (11.5%)" "respiratory chain complex I (11.5%) plasma membrane (10.6%)" "NADH dehydrogenase (ubiquinone) activity (11.5%) iron ion binding (10.6%) quinone binding (10.6%)" "IPR006137 (52.2%) IPR006138 (47.8%)" "NADH:ubiquinone oxidoreductase-like, 20kDa subunit (52.2%) NADH-ubiquinone oxidoreductase, 20 Kd subunit (47.8%)" FSDTFDMK root "GO:0005987 (21.1%) GO:0009765 (7.9%)" "GO:0005737 (21.1%) GO:0009507 (7.9%) GO:0016020 (7.9%)" "GO:0004575 (21.1%) GO:0016168 (7.9%)" "sucrose catabolic process (21.1%) photosynthesis, light harvesting (7.9%)" "cytoplasm (21.1%) chloroplast (7.9%) membrane (7.9%)" "sucrose alpha-glucosidase activity (21.1%) chlorophyll binding (7.9%)" "IPR001362 (12.9%) IPR013148 (12.9%) IPR013189 (12.9%)" "Glycoside hydrolase, family 32 (12.9%) Glycosyl hydrolase family 32, N-terminal (12.9%) Glycosyl hydrolase family 32, C-terminal (12.9%)" GNLWLGSEDDGVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (33.3%) GO:0003700 (33.3%) GO:0043565 (33.3%)" "phosphorelay sensor kinase activity (33.3%) DNA-binding transcription factor activity (33.3%) sequence-specific DNA binding (33.3%)" "IPR001789 (6.4%) IPR003594 (6.4%) IPR003661 (6.4%)" "Signal transduction response regulator, receiver domain (6.4%) Histidine kinase/HSP90-like ATPase domain (6.4%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.4%)" YYDVLER root "1.1.1.95 (30.6%) 1.1.1.399 (26.5%) 3.2.1.185 (14.3%)" "phosphoglycerate dehydrogenase (30.6%) 2-oxoglutarate reductase (26.5%) non-reducing end beta-L-arabinofuranosidase (14.3%)" "GO:0005975 (27.9%) GO:0051301 (2.8%) GO:0009070 (1.8%)" "GO:0016514 (1.4%) GO:0016586 (1.4%) GO:0005886 (1.1%)" "GO:0016787 (17.3%) GO:0005524 (12.4%) GO:0004617 (1.8%)" "carbohydrate metabolic process (27.9%) cell division (2.8%) serine family amino acid biosynthetic process (1.8%)" "SWI/SNF complex (1.4%) RSC-type complex (1.4%) plasma membrane (1.1%)" "hydrolase activity (17.3%) ATP binding (12.4%) phosphoglycerate dehydrogenase activity (1.8%)" "IPR012878 (9.5%) IPR049174 (9.5%) IPR049046 (9.4%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (9.5%) Non-reducing end beta-L-arabinofuranosidase-like (9.5%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (9.4%)" NDLLTEYLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" NFVVEEYQLLQAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.48 (100%) indole-3-glycerol-phosphate synthase (100%) GO:0000162 (32.9%) "GO:0004425 (32.9%) GO:0004640 (32.9%) GO:0016757 (1.2%)" L-tryptophan biosynthetic process (32.9%) "indole-3-glycerol-phosphate synthase activity (32.9%) phosphoribosylanthranilate isomerase activity (32.9%) glycosyltransferase activity (1.2%)" "IPR013798 (20.8%) IPR045186 (20.8%) IPR001468 (20%)" "Indole-3-glycerol phosphate synthase domain (20.8%) Indole-3-glycerol phosphate synthase (20.8%) Indole-3-glycerol phosphate synthase, conserved site (20%)" SGEFLTYNLYYNWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR021457 (100%) Protein of unknown function DUF3108 (100%) VVNLPSFAVK Pseudomonadati Bacteria Pseudomonadati "GO:0006412 (19.9%) GO:0042274 (19.9%)" "GO:0015935 (19.9%) GO:0005840 (0.3%)" "GO:0003735 (19.9%) GO:0019843 (19.9%) GO:0003723 (0.3%)" "translation (19.9%) ribosomal small subunit biogenesis (19.9%)" "small ribosomal subunit (19.9%) ribosome (0.3%)" "structural constituent of ribosome (19.9%) rRNA binding (19.9%) RNA binding (0.3%)" "IPR036986 (16.9%) IPR001912 (16.6%) IPR002942 (16.6%)" "RNA-binding S4 domain superfamily (16.9%) Small ribosomal subunit protein uS4, N-terminal (16.6%) RNA-binding S4 domain (16.6%)" CNLNTLDQDLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.6%) GO:0006221 (13.5%) GO:0006526 (12.5%)" GO:0005737 (14.6%) "GO:0004088 (14.6%) GO:0005524 (14.6%) GO:0046872 (14.6%)" "glutamine metabolic process (14.6%) pyrimidine nucleotide biosynthetic process (13.5%) L-arginine biosynthetic process (12.5%)" cytoplasm (14.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.6%) ATP binding (14.6%) metal ion binding (14.6%)" "IPR005480 (11.8%) IPR005479 (10.9%) IPR011761 (10.9%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (11.8%) Carbamoyl phosphate synthase, ATP-binding domain (10.9%) ATP-grasp fold (10.9%)" DGYHNLETVFYPLPLTDALELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.5%) GO:0019288 (24.5%)" "GO:0005524 (25.5%) GO:0050515 (25.5%)" "terpenoid biosynthetic process (24.5%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.5%)" "ATP binding (25.5%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.5%)" "IPR006204 (17%) IPR014721 (17%) IPR020568 (17%)" "GHMP kinase N-terminal domain (17%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17%) Ribosomal protein uS5 domain 2-type superfamily (17%)" NLGLSTSADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR035986 (100%) PKD domain superfamily (100%) FLQSETLR root "1.8.1.2 (66.7%) 2.1.1.193 (22.2%) 3.6.4.12 (11.1%)" "assimilatory sulfite reductase (NADPH) (66.7%) 16S rRNA (uracil(1498)-N(3))-methyltransferase (22.2%) DNA helicase (11.1%)" "GO:0000103 (6.6%) GO:0019344 (4.4%) GO:0000271 (1.1%)" "GO:0005737 (8.8%) GO:0009337 (6.6%) GO:0016020 (3.3%)" "GO:0046872 (7.7%) GO:0010181 (6.6%) GO:0020037 (6.6%)" "sulfate assimilation (6.6%) cysteine biosynthetic process (4.4%) polysaccharide biosynthetic process (1.1%)" "cytoplasm (8.8%) sulfite reductase complex (NADPH) (6.6%) membrane (3.3%)" "metal ion binding (7.7%) FMN binding (6.6%) heme binding (6.6%)" "IPR001094 (4.4%) IPR002880 (4.4%) IPR005117 (4.4%)" "Flavodoxin-like (4.4%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (4.4%) Nitrite/Sulfite reductase ferredoxin-like domain (4.4%)" NYQDQPGGQFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000184 (50%) IPR039910 (50%)" "Bacterial surface antigen (D15) (50%) Surface antigen D15-like (50%)" MGFDPENDMEELLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (20%) "GO:0005524 (20%) GO:0008784 (20%) GO:0016881 (20%)" D-alanine biosynthetic process (20%) "ATP binding (20%) alanine racemase activity (20%) acid-amino acid ligase activity (20%)" "IPR000821 (10.3%) IPR001608 (10.3%) IPR011079 (10.3%)" "Alanine racemase (10.3%) Alanine racemase, N-terminal (10.3%) Alanine racemase, C-terminal (10.3%)" PVYNGFDAVDSDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.3%) IPR023996 (15.3%) IPR023997 (15.3%)" "TonB-dependent receptor, plug domain (15.3%) TonB-dependent outer membrane protein, SusC/RagA (15.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.3%)" YFFTNVK root 2.3.2.27 (100%) RING-type E3 ubiquitin transferase (100%) "GO:0006520 (38.8%) GO:0006511 (1.5%) GO:0016567 (1.5%)" "GO:0016020 (3%) GO:0000151 (1.5%) GO:0005829 (1.5%)" "GO:0016829 (38.8%) GO:0008270 (3%) GO:0008194 (1.5%)" "amino acid metabolic process (38.8%) ubiquitin-dependent protein catabolic process (1.5%) protein ubiquitination (1.5%)" "membrane (3%) ubiquitin ligase complex (1.5%) cytosol (1.5%)" "lyase activity (38.8%) zinc ion binding (3%) UDP-glycosyltransferase activity (1.5%)" "IPR001597 (23.2%) IPR015421 (22.3%) IPR015422 (22.3%)" "Aromatic amino acid beta-eliminating lyase/threonine aldolase (23.2%) Pyridoxal phosphate-dependent transferase, major domain (22.3%) Pyridoxal phosphate-dependent transferase, small domain (22.3%)" KADVTSAVVSVK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ALEYLDK root "6.3.1.2 (51.8%) 5.4.2.12 (10.1%) 2.7.7.6 (7.2%)" "glutamine synthetase (51.8%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (10.1%) DNA-directed RNA polymerase (7.2%)" "GO:0006542 (4.6%) GO:0019740 (4.6%) GO:0006096 (1.4%)" "GO:0016020 (8%) GO:0005737 (6.7%) GO:0005829 (2.7%)" "GO:0005524 (8.5%) GO:0046872 (5.5%) GO:0004356 (4.7%)" "glutamine biosynthetic process (4.6%) nitrogen utilization (4.6%) glycolytic process (1.4%)" "membrane (8%) cytoplasm (6.7%) cytosol (2.7%)" "ATP binding (8.5%) metal ion binding (5.5%) glutamine synthetase activity (4.7%)" "IPR011990 (5.9%) IPR019734 (4.3%) IPR008146 (3.2%)" "Tetratricopeptide-like helical domain superfamily (5.9%) Tetratricopeptide repeat (4.3%) Glutamine synthetase, catalytic domain (3.2%)" LYPLGLQTFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.8%) IPR012547 (35.8%) IPR027417 (25.4%)" "AAA-ATPase-like domain (38.8%) PD-(D/E)XK nuclease superfamily 9 (35.8%) P-loop containing nucleoside triphosphate hydrolase (25.4%)" VSLPLYYSVTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR025684 (49.3%) IPR026377 (49.3%) IPR023614 (1.4%)" "Gliding motility protein SprA N-terminal domain (49.3%) Cell surface SprA (49.3%) Porin domain superfamily (1.4%)" LVLTELPYGVNK root "5.6.2.2 (97.2%) 5.99.1.3 (2.8%)" "DNA topoisomerase (ATP-hydrolyzing) (97.2%) Transferred entry: 5.6.2.2 (2.8%)" "GO:0006265 (13.6%) GO:0006261 (10.5%)" "GO:0009330 (13.6%) GO:0005737 (11.1%) GO:0005694 (10.5%)" "GO:0003677 (13.6%) GO:0005524 (13.6%) GO:0034335 (10.5%)" "DNA topological change (13.6%) DNA-templated DNA replication (10.5%)" "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (13.6%) cytoplasm (11.1%) chromosome (10.5%)" "DNA binding (13.6%) ATP binding (13.6%) DNA negative supercoiling activity (10.5%)" "IPR002205 (13.2%) IPR050220 (13.2%) IPR013758 (13%)" "DNA topoisomerase, type IIA, domain A (13.2%) Type II DNA Topoisomerases (13.2%) DNA topoisomerase, type IIA, domain A, alpha-beta (13%)" ENVDDFLEKLETVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008483 (33.3%) GO:0030170 (33.3%) GO:0042802 (33.3%)" "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%) identical protein binding (33.3%)" "IPR005814 (16.7%) IPR015421 (16.7%) IPR015422 (16.7%)" "Aminotransferase class-III (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%) Pyridoxal phosphate-dependent transferase, small domain (16.7%)" GQVVVDAATGLPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (7.7%) GO:0009279 (92.3%) iron ion transport (7.7%) cell outer membrane (92.3%) "IPR012910 (14.5%) IPR023996 (14.5%) IPR023997 (14.5%)" "TonB-dependent receptor, plug domain (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.5%)" DALNCVLMSPTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.4.13 (61.1%) 3.6.4.- (38.9%)" "RNA helicase (61.1%) Acting on ATP; involved in cellular and subcellular movement (38.9%)" GO:0005829 (19.9%) "GO:0003676 (20%) GO:0003724 (20%) GO:0005524 (20%)" cytosol (19.9%) "nucleic acid binding (20%) RNA helicase activity (20%) ATP binding (20%)" "IPR011545 (14.4%) IPR014001 (14.4%) IPR014014 (14.4%)" "DEAD/DEAH-box helicase domain (14.4%) Helicase superfamily 1/2, ATP-binding domain (14.4%) RNA helicase, DEAD-box type, Q motif (14.4%)" EALDNNPGLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LKVNGDDAAPLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.-.-.- (100%) Oxidoreductases (100%) GO:0034599 (50%) GO:0004601 (50%) cellular response to oxidative stress (50%) peroxidase activity (50%) "IPR000889 (34.4%) IPR036249 (34.4%) IPR029760 (31.3%)" "Glutathione peroxidase (34.4%) Thioredoxin-like superfamily (34.4%) Glutathione peroxidase conserved site (31.3%)" LLDDLKNTVTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) "IPR003663 (16.7%) IPR005828 (16.7%) IPR005829 (16.7%)" "Sugar/inositol transporter (16.7%) Major facilitator, sugar transporter-like (16.7%) Sugar transporter, conserved site (16.7%)" VDYYNLTVDDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.9%) GO:0043335 (15.9%) GO:0051083 (15.9%)" GO:0005737 (4.8%) "GO:0003755 (15.9%) GO:0043022 (15.9%) GO:0044183 (15.9%)" "protein transport (15.9%) protein unfolding (15.9%) 'de novo' cotranslational protein folding (15.9%)" cytoplasm (4.8%) "peptidyl-prolyl cis-trans isomerase activity (15.9%) ribosome binding (15.9%) protein folding chaperone (15.9%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR027304 (18.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor/SurA domain superfamily (18.4%)" DLYWAFWHPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.51 (100%) 1-acylglycerol-3-phosphate O-acyltransferase (100%) GO:0006654 (34.9%) GO:0016020 (30.1%) GO:0003841 (34.9%) phosphatidic acid biosynthetic process (34.9%) membrane (30.1%) 1-acylglycerol-3-phosphate O-acyltransferase activity (34.9%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) ENSSSADDQSSAPTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR032167 (50%)" "Immunoglobulin-like fold (50%) Protein of unknown function DUF5003 (50%)" EMEGKPVTLTQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.1%) IPR002772 (9.1%) IPR011658 (9.1%)" "Glycoside hydrolase, family 3, N-terminal (9.1%) Glycoside hydrolase family 3 C-terminal domain (9.1%) PA14 domain (9.1%)" VDPDVNVPLLSDMSSDLMSRPVDVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20.2%) GO:0008615 (19.3%)" GO:0005737 (20.2%) "GO:0004648 (20.2%) GO:0030170 (20.2%)" "L-serine biosynthetic process (20.2%) pyridoxine biosynthetic process (19.3%)" cytoplasm (20.2%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20.2%) pyridoxal phosphate binding (20.2%)" "IPR000192 (20.8%) IPR022278 (20.8%) IPR015421 (19.8%)" "Aminotransferase class V domain (20.8%) Phosphoserine aminotransferase (20.8%) Pyridoxal phosphate-dependent transferase, major domain (19.8%)" HTDNLTDVTPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.5%) IPR044993 (9.5%) IPR002772 (9.1%)" "Glycoside hydrolase, family 3, N-terminal (9.5%) Beta-D-xylosidase (9.5%) Glycoside hydrolase family 3 C-terminal domain (9.1%)" EVPEATTFLVAPYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011250 (50%) IPR027385 (50%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (50%) Outer membrane protein, beta-barrel domain (50%)" TAFGTDNNLSVSGSLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (6.9%) GO:0009279 (86.2%) GO:0015344 (6.9%) siderophore transmembrane transport (6.9%) cell outer membrane (86.2%) siderophore uptake transmembrane transporter activity (6.9%) "IPR012910 (12.3%) IPR023997 (12.3%) IPR039426 (12.3%)" "TonB-dependent receptor, plug domain (12.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.3%) TonB-dependent receptor-like (12.3%)" DHNEAFASLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018485 (20.5%) IPR043129 (20.5%) IPR050406 (20.5%)" "Carbohydrate kinase FGGY, C-terminal (20.5%) ATPase, nucleotide binding domain (20.5%) FGGY Carbohydrate Kinase (20.5%)" VSQLKEETLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) GSYLDSDGNLTWDMAENQAYHHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) MNSWVYAGFDETYK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001278 (12.6%) IPR001412 (12.6%) IPR008909 (12.6%)" "Arginine-tRNA ligase (12.6%) Aminoacyl-tRNA synthetase, class I, conserved site (12.6%) DALR anticodon binding (12.6%)" LEQTSLYDACLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (78.6%) GO:0015344 (21.4%) cell outer membrane (78.6%) siderophore uptake transmembrane transporter activity (21.4%) "IPR036942 (78.6%) IPR039426 (21.4%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (78.6%) TonB-dependent receptor-like (21.4%)" FHPWLFSGALQAMDEGLEEGDLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006364 (20%) GO:0032259 (20%)" GO:0005737 (20%) "GO:0003723 (20%) GO:0008168 (20%)" "rRNA processing (20%) methylation (20%)" cytoplasm (20%) "RNA binding (20%) methyltransferase activity (20%)" "IPR002478 (16.7%) IPR015947 (16.7%) IPR019614 (16.7%)" "PUA domain (16.7%) PUA-like superfamily (16.7%) S-adenosylmethionine-dependent methyltransferase (16.7%)" GGMNVLLELSVPDVLENLADHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" SLVENLDKFYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.3.43 (50%) 3.6.3.44 (50%)" "Transferred entry: 7.4.2.5 (50%) Transferred entry: 7.6.2.2 (50%)" "GO:0006508 (15.9%) GO:0090374 (0.9%)" "GO:0005886 (16.4%) GO:0005743 (0.5%)" "GO:0005524 (16.8%) GO:0015421 (16.8%) GO:0016887 (16.8%)" "proteolysis (15.9%) oligopeptide export from mitochondrion (0.9%)" "plasma membrane (16.4%) mitochondrial inner membrane (0.5%)" "ATP binding (16.8%) ABC-type oligopeptide transporter activity (16.8%) ATP hydrolysis activity (16.8%)" "IPR003439 (13%) IPR039421 (13%) IPR003593 (12.7%)" "ABC transporter-like, ATP-binding domain (13%) Type 1 protein exporter (13%) AAA+ ATPase domain (12.7%)" GFNALLDGEVDDLPEQAFLNVGTLEDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (22.4%) GO:0045259 (22.4%)" "GO:0005524 (22.4%) GO:0046933 (22.4%) GO:0016787 (10.6%)" "plasma membrane (22.4%) proton-transporting ATP synthase complex (22.4%)" "ATP binding (22.4%) proton-transporting ATP synthase activity, rotational mechanism (22.4%) hydrolase activity (10.6%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" TLPDFMDYKDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0012505 (50%) GO:0016020 (50%)" "endomembrane system (50%) membrane (50%)" "IPR010652 (50%) IPR016983 (50%)" "Domain of unknown function DUF1232 (50%) Uncharacterised conserved protein UCP031804 (50%)" EDHNFVLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (20.4%) IPR051795 (20.4%) IPR006710 (19.9%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (20.4%) Glycosyl Hydrolase Family 43 (20.4%) Glycoside hydrolase, family 43 (19.9%)" TELLDKLAAGAELTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030261 (17.6%) GO:0006270 (5.9%) GO:0006351 (5.9%)" "GO:0005829 (17.6%) GO:1990103 (5.9%) GO:1990178 (5.9%)" "GO:0003677 (17.6%) GO:0030527 (17.6%) GO:0042802 (5.9%)" "chromosome condensation (17.6%) DNA replication initiation (5.9%) DNA-templated transcription (5.9%)" "cytosol (17.6%) DnaA-HU complex (5.9%) HU-DNA complex (5.9%)" "DNA binding (17.6%) structural constituent of chromatin (17.6%) identical protein binding (5.9%)" "IPR000119 (33.3%) IPR010992 (33.3%) IPR020816 (33.3%)" "Histone-like DNA-binding protein (33.3%) Integration host factor (IHF)-like DNA-binding domain superfamily (33.3%) Histone-like DNA-binding protein, conserved site (33.3%)" VVSDGGAEVMPAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (20%) "GO:0005829 (20%) GO:0016020 (20%)" "GO:0003743 (20%) GO:0043022 (20%)" ribosome disassembly (20%) "cytosol (20%) membrane (20%)" "translation initiation factor activity (20%) ribosome binding (20%)" "IPR001288 (17.2%) IPR019813 (17.2%) IPR019814 (17.2%)" "Translation initiation factor 3 (17.2%) Translation initiation factor 3, conserved site (17.2%) Translation initiation factor 3, N-terminal (17.2%)" LEWYNMYVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.2%) IPR012910 (20.2%) IPR008969 (19.7%)" "TonB-dependent receptor-like, beta-barrel (20.2%) TonB-dependent receptor, plug domain (20.2%) Carboxypeptidase-like, regulatory domain superfamily (19.7%)" LRLELFNQYGSTGSNPGLNQAQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri WSELANELFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR001375 (33.3%) IPR029058 (33.3%) IPR052920 (33.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (33.3%) Alpha/Beta hydrolase fold (33.3%) Potential DNA-binding regulatory protein (33.3%)" TGLQLGFK root 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (24.3%) GO:0016052 (24.3%) GO:0010468 (0.4%)" "GO:0005737 (24.7%) GO:0005634 (0.4%)" "GO:0004139 (24.3%) GO:0000977 (0.4%) GO:0000981 (0.4%)" "deoxyribonucleotide catabolic process (24.3%) carbohydrate catabolic process (24.3%) regulation of gene expression (0.4%)" "cytoplasm (24.7%) nucleus (0.4%)" "deoxyribose-phosphate aldolase activity (24.3%) RNA polymerase II transcription regulatory region sequence-specific DNA binding (0.4%) DNA-binding transcription factor activity, RNA polymerase II-specific (0.4%)" "IPR002915 (31.6%) IPR011343 (31.6%) IPR013785 (31%)" "DeoC/FbaB/LacD aldolase (31.6%) Deoxyribose-phosphate aldolase (31.6%) Aldolase-type TIM barrel (31%)" GFNCFYPYLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (2.8%) "GO:0000155 (24.8%) GO:0003700 (24.1%) GO:0005524 (24.1%)" membrane (2.8%) "phosphorelay sensor kinase activity (24.8%) DNA-binding transcription factor activity (24.1%) ATP binding (24.1%)" "IPR011123 (7%) IPR001789 (6.8%) IPR003594 (6.8%)" "Two component regulator three Y (7%) Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%)" TYLGDPNPDFTFGLTNTFSYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" ELAMPEEYKLYCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (16.7%) GO:0006520 (16.7%) GO:0044205 (16.7%)" GO:0005829 (16.7%) "GO:0004070 (16.7%) GO:0016597 (16.7%)" "'de novo' pyrimidine nucleobase biosynthetic process (16.7%) amino acid metabolic process (16.7%) 'de novo' UMP biosynthetic process (16.7%)" cytosol (16.7%) "aspartate carbamoyltransferase activity (16.7%) amino acid binding (16.7%)" "IPR002082 (20.3%) IPR006130 (20.3%) IPR006131 (20.3%)" "Aspartate carbamoyltransferase (20.3%) Aspartate/ornithine carbamoyltransferase (20.3%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.3%)" LPEVPSALLEMLSHQNFPDMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR003961 (25.8%) IPR033803 (25.8%) IPR013783 (24.2%)" "Fibronectin type III (25.8%) Golvesin/Xly, CBD-like (25.8%) Immunoglobulin-like fold (24.2%)" QLHLVPLSLSYEYDPCDFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) VEPQDFK root "2.2.1.9 (78.1%) 6.3.2.13 (18.8%) 2.1.1.- (3.1%)" "2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (78.1%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (18.8%) Methyltransferases (3.1%)" "GO:0009234 (12.7%) GO:0008360 (2%) GO:0009252 (2%)" "GO:0005737 (3.6%) GO:0005874 (1%) GO:0016020 (1%)" "GO:0000287 (14.7%) GO:0030976 (14.2%) GO:0030145 (12.7%)" "menaquinone biosynthetic process (12.7%) regulation of cell shape (2%) peptidoglycan biosynthetic process (2%)" "cytoplasm (3.6%) microtubule (1%) membrane (1%)" "magnesium ion binding (14.7%) thiamine pyrophosphate binding (14.2%) manganese ion binding (12.7%)" "IPR011766 (15.3%) IPR029061 (14.2%) IPR004433 (13.7%)" "Thiamine pyrophosphate enzyme, TPP-binding (15.3%) Thiamin diphosphate-binding fold (14.2%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (13.7%)" DRYDWWLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0002098 (25%) GO:0030488 (25%)" GO:0005829 (25%) GO:0050660 (25%) "tRNA wobble uridine modification (25%) tRNA methylation (25%)" cytosol (25%) flavin adenine dinucleotide binding (25%) "IPR002218 (11.3%) IPR004416 (11.3%) IPR020595 (11.3%)" "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related (11.3%) tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG (11.3%) MnmG-related, conserved site (11.3%)" AAEAAYTLDQSAVEEMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.- (100%) Transaminases (100%) GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004838 (16.7%) IPR004839 (16.7%) IPR015421 (16.7%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.7%) Aminotransferase, class I/classII, large domain (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" QNFYTPEVLTESLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.9%) IPR050306 (33.9%) IPR029056 (32.1%)" "Carbohydrate kinase PfkB (33.9%) PfkB Carbohydrate Kinase (33.9%) Ribokinase-like (32.1%)" TEMLAEAR root "3.5.2.3 (44.4%) 5.1.1.1 (22.2%) 1.8.1.4 (11.1%)" "dihydroorotase (44.4%) alanine racemase (22.2%) dihydrolipoyl dehydrogenase (11.1%)" "GO:0006145 (4.5%) GO:0006221 (4.5%) GO:0006281 (4.5%)" "GO:0009279 (29.2%) GO:0005737 (6.7%) GO:0005829 (1.1%)" "GO:0003676 (4.5%) GO:0004038 (4.5%) GO:0004151 (4.5%)" "purine nucleobase catabolic process (4.5%) pyrimidine nucleotide biosynthetic process (4.5%) DNA repair (4.5%)" "cell outer membrane (29.2%) cytoplasm (6.7%) cytosol (1.1%)" "nucleic acid binding (4.5%) allantoinase activity (4.5%) dihydroorotase activity (4.5%)" "IPR012944 (12.6%) IPR033985 (12.6%) IPR011990 (12.1%)" "RagB/SusD domain (12.6%) SusD-like, N-terminal (12.6%) Tetratricopeptide-like helical domain superfamily (12.1%)" ALNLPHVMLTGGYMLSNPNVFNGFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.3%) "GO:0009279 (20.3%) GO:1990281 (20.3%)" "GO:0015288 (20.3%) GO:0015562 (20.3%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.3%) efflux pump complex (20.3%)" "porin activity (20.3%) efflux transmembrane transporter activity (20.3%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" DYMADPSANVFNGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (33.8%) IPR052176 (33.8%) IPR023296 (32.4%)" "Glycoside hydrolase, family 43 (33.8%) Glycosyl Hydrolase Family 43 Enzymes (33.8%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.4%)" LLYSANTFENAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) SLHDYFMVTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010221 (100%) VCBS domain (100%) VVASEDGEPVLGASLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (32.7%) GO:0009279 (34.7%) GO:0015344 (32.7%) siderophore transmembrane transport (32.7%) cell outer membrane (34.7%) siderophore uptake transmembrane transporter activity (32.7%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" GQQETFTSPELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015920 (50%) GO:0043190 (50%) lipopolysaccharide transport (50%) ATP-binding cassette (ABC) transporter complex (50%) IPR005495 (100%) Permease LptG/LptF-related (100%) KFQEAQGLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.99.12 (100%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (100%) "GO:0009244 (25%) GO:0009245 (25%)" GO:0005886 (25%) "GO:0016740 (17.5%) GO:0043842 (7.5%)" "lipopolysaccharide core region biosynthetic process (25%) lipid A biosynthetic process (25%)" plasma membrane (25%) "transferase activity (17.5%) Kdo transferase activity (7.5%)" "IPR007507 (33.9%) IPR039901 (33.9%) IPR038107 (32.2%)" "3-deoxy-D-manno-octulosonic-acid transferase, N-terminal (33.9%) 3-deoxy-D-manno-octulosonic acid transferase (33.9%) 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily (32.2%)" ATLAQPGGDKLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" LSLVPGFLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.3 (53.5%) 2.7.2.4 (46.5%)" "homoserine dehydrogenase (53.5%) aspartate kinase (46.5%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.1%) IPR001341 (7.1%) IPR001342 (7.1%)" "Aspartate/glutamate/uridylate kinase (7.1%) Aspartate kinase (7.1%) Homoserine dehydrogenase, catalytic (7.1%)" KNLGQHFLTDLNLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.182 (98.4%) 2.1.1.- (1.6%)" "16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (98.4%) Methyltransferases (1.6%)" GO:0005829 (33.3%) "GO:0003723 (33.3%) GO:0052908 (19.8%) GO:0000179 (13.6%)" cytosol (33.3%) "RNA binding (33.3%) 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity (19.8%) rRNA (adenine-N6,N6-)-dimethyltransferase activity (13.6%)" "IPR001737 (16.8%) IPR011530 (16.8%) IPR020596 (16.8%)" "Ribosomal RNA adenine methyltransferase KsgA/Erm (16.8%) Ribosomal RNA adenine dimethylase (16.8%) Ribosomal RNA adenine methylase transferase, conserved site (16.8%)" YWLNFTK root 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0006874 (1%) GO:0006891 (1%) GO:0009860 (1%)" "GO:0016020 (11.4%) GO:0005634 (8.6%) GO:0012505 (4.8%)" "GO:0016787 (32.4%) GO:0000981 (8.6%) GO:0003677 (8.6%)" "intracellular calcium ion homeostasis (1%) intra-Golgi vesicle-mediated transport (1%) pollen tube growth (1%)" "membrane (11.4%) nucleus (8.6%) endomembrane system (4.8%)" "hydrolase activity (32.4%) DNA-binding transcription factor activity, RNA polymerase II-specific (8.6%) DNA binding (8.6%)" "IPR002018 (14.8%) IPR019826 (13.9%) IPR029058 (13.9%)" "Carboxylesterase, type B (14.8%) Carboxylesterase type B, active site (13.9%) Alpha/Beta hydrolase fold (13.9%)" FAYQALLFQLTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) EVVFNPLK root 4.4.1.13 (100%) cysteine-S-conjugate beta-lyase (100%) GO:0016020 (1.6%) "GO:0016829 (47.6%) GO:0030170 (47.6%) GO:0016757 (3.2%)" membrane (1.6%) "lyase activity (47.6%) pyridoxal phosphate binding (47.6%) glycosyltransferase activity (3.2%)" "IPR004839 (16.6%) IPR027619 (16.6%) IPR051798 (16.6%)" "Aminotransferase, class I/classII, large domain (16.6%) C-S lyase, PatB-like (16.6%) Class-II Pyridoxal-Phosphate-Dependent Aminotransferase (16.6%)" EFNDSLDHNNDVE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.9%) IPR003029 (7.9%) IPR004087 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) S1 domain (7.9%) K Homology domain (7.9%)" VDEQVLFVPFCVPGDVVDLQVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.1.1.190 (95.7%) 2.1.1.- (4.3%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (95.7%) Methyltransferases (4.3%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR002792 (17.4%) IPR010280 (17.4%) IPR030390 (16.7%)" "TRAM domain (17.4%) (Uracil-5)-methyltransferase family (17.4%) RNA methyltransferase TrmA, active site (16.7%)" LGMNGQQLAMLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (20%) GO:0042026 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0016887 (20%)" "cellular response to heat (20%) protein refolding (20%)" cytoplasm (20%) "ATP binding (20%) ATP hydrolysis activity (20%)" "IPR004176 (8.8%) IPR003593 (8.4%) IPR003959 (8.4%)" "Clp, repeat (R) N-terminal domain (8.8%) AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%)" AELHVDHHLDSVEQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.11 (100%) glutamate 5-kinase (100%) "GO:0055129 (22.9%) GO:0006561 (2.1%)" GO:0005829 (25%) "GO:0004349 (25%) GO:0005524 (25%)" "L-proline biosynthetic process (22.9%) obsolete proline biosynthetic process (2.1%)" cytosol (25%) "glutamate 5-kinase activity (25%) ATP binding (25%)" "IPR001048 (18.8%) IPR005715 (18.8%) IPR041739 (17.2%)" "Aspartate/glutamate/uridylate kinase (18.8%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (18.8%) Glutamate-5-kinase domain (17.2%)" SFDFGPPDFDFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella AEAQFGFLMNAFK Bacteria Bacteria 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0004815 (20%) GO:0005524 (20%) GO:0003676 (19.7%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "aspartate-tRNA ligase activity (20%) ATP binding (20%) nucleic acid binding (19.7%)" "IPR004364 (9.2%) IPR002312 (9.1%) IPR004115 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%)" LHFENPQSFLAFTSEYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QTLAFLDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TADYVLR root "3.1.1.29 (70.9%) 3.2.1.40 (7%) 1.-.-.- (4.7%)" "peptidyl-tRNA hydrolase (70.9%) alpha-L-rhamnosidase (7%) Oxidoreductases (4.7%)" "GO:0006515 (5.6%) GO:0072344 (5.6%) GO:0043165 (3.1%)" "GO:0005737 (10.2%) GO:0016020 (3.9%) GO:1990063 (2.6%)" "GO:0016301 (7.5%) GO:0000976 (6.5%) GO:0003700 (6.4%)" "protein quality control for misfolded or incompletely synthesized proteins (5.6%) rescue of stalled ribosome (5.6%) Gram-negative-bacterium-type cell outer membrane assembly (3.1%)" "cytoplasm (10.2%) membrane (3.9%) Bam protein complex (2.6%)" "kinase activity (7.5%) transcription cis-regulatory region binding (6.5%) DNA-binding transcription factor activity (6.4%)" "IPR027417 (7.3%) IPR009057 (5.5%) IPR001647 (5.3%)" "P-loop containing nucleoside triphosphate hydrolase (7.3%) Homedomain-like superfamily (5.5%) DNA-binding HTH domain, TetR-type (5.3%)" EMLENEVSDDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016627 (50.8%) GO:0050660 (49.2%)" "oxidoreductase activity, acting on the CH-CH group of donors (50.8%) flavin adenine dinucleotide binding (49.2%)" "IPR009075 (10.3%) IPR020964 (10.3%) IPR052166 (10.3%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10.3%) Acyl-CoA dehydrogenase, C-terminal (10.3%) Diverse substrate specificity acyl-CoA dehydrogenase (10.3%)" QFALVDAGMTDLLR Pseudomonadati Bacteria Pseudomonadati 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.8%) "GO:0008836 (33.8%) GO:0030170 (32.5%)" lysine biosynthetic process via diaminopimelate (33.8%) "diaminopimelate decarboxylase activity (33.8%) pyridoxal phosphate binding (32.5%)" "IPR022643 (14.5%) IPR002986 (14.2%) IPR009006 (14.2%)" "Orn/DAP/Arg decarboxylase 2, C-terminal (14.5%) Diaminopimelate decarboxylase, LysA (14.2%) Alanine racemase/group IV decarboxylase, C-terminal (14.2%)" VNGEALKGELSGNSLQVDATELEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" LNNMGYNVDATLYMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.4%) IPR039426 (20.4%) IPR012910 (19.9%)" "TonB-dependent receptor-like, beta-barrel (20.4%) TonB-dependent receptor-like (20.4%) TonB-dependent receptor, plug domain (19.9%)" KMVDGFCYYDELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (50%) 3.4.21.- (50%)" "Acting on peptide bonds (peptidases) (50%) Serine endopeptidases (50%)" GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.9%) IPR004634 (16.9%) IPR004635 (16.9%)" "Peptidase S49 (16.9%) Peptidase S49, protease IV (16.9%) Peptidase S49, SppA (16.9%)" VQLPTAYLK root "3.2.1.1 (81.8%) 3.4.22.49 (18.2%)" "alpha-amylase (81.8%) separase (18.2%)" "GO:0005975 (22%) GO:0006508 (4.9%) GO:0051307 (4.9%)" "GO:0005634 (4.9%) GO:0005737 (4.9%) GO:0005813 (4.9%)" "GO:0004556 (22%) GO:0043169 (22%) GO:0004197 (4.9%)" "carbohydrate metabolic process (22%) proteolysis (4.9%) meiotic chromosome separation (4.9%)" "nucleus (4.9%) cytoplasm (4.9%) centrosome (4.9%)" "alpha-amylase activity (22%) cation binding (22%) cysteine-type endopeptidase activity (4.9%)" "IPR006046 (15.5%) IPR006047 (15.5%) IPR013780 (15.5%)" "Alpha amylase (15.5%) Glycosyl hydrolase family 13, catalytic domain (15.5%) Glycosyl hydrolase, all-beta (15.5%)" DLQELADNSQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.8%) IPR004634 (16.8%) IPR004635 (16.8%)" "Peptidase S49 (16.8%) Peptidase S49, protease IV (16.8%) Peptidase S49, SppA (16.8%)" DAGLDVHSFMPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.- (100%) Transferases for other substituted phosphate groups (100%) GO:0032049 (32.8%) GO:0005886 (32.8%) "GO:0008808 (32.8%) GO:0016787 (1.6%)" cardiolipin biosynthetic process (32.8%) plasma membrane (32.8%) "cardiolipin synthase activity (32.8%) hydrolase activity (1.6%)" "IPR001736 (20%) IPR022924 (20%) IPR025202 (20%)" "Phospholipase D/Transphosphatidylase (20%) Cardiolipin synthase (20%) Phospholipase D-like domain (20%)" MYSSAHAQAYEDWMGGVEGTELPYDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" VGDVDLQLGVTGTYYNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" LLHLEEELHKR root "GO:0034605 (19%) GO:0042026 (15.6%) GO:0006508 (2.3%)" "GO:0005737 (19.1%) GO:0009507 (0.3%) GO:0009532 (0.3%)" "GO:0005524 (19.8%) GO:0016887 (19.8%) GO:0008233 (2.3%)" "cellular response to heat (19%) protein refolding (15.6%) proteolysis (2.3%)" "cytoplasm (19.1%) chloroplast (0.3%) plastid stroma (0.3%)" "ATP binding (19.8%) ATP hydrolysis activity (19.8%) peptidase activity (2.3%)" "IPR003959 (8.6%) IPR050130 (8.6%) IPR003593 (8.6%)" "ATPase, AAA-type, core (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) AAA+ ATPase domain (8.6%)" TPLSEFR root "5.6.2.2 (89.4%) 3.2.1.- (3%) 3.2.1.196 (2.7%)" "DNA topoisomerase (ATP-hydrolyzing) (89.4%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (3%) limit dextrin alpha-1,6-maltotetraose-hydrolase (2.7%)" "GO:0006265 (10.2%) GO:0006261 (9.3%) GO:0005980 (1.1%)" "GO:0005737 (11.6%) GO:0009330 (10.2%) GO:0005694 (9.7%)" "GO:0005524 (10.7%) GO:0003677 (10.3%) GO:0034335 (8.4%)" "DNA topological change (10.2%) DNA-templated DNA replication (9.3%) glycogen catabolic process (1.1%)" "cytoplasm (11.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (10.2%) chromosome (9.7%)" "ATP binding (10.7%) DNA binding (10.3%) DNA negative supercoiling activity (8.4%)" "IPR006691 (9.5%) IPR050220 (9.5%) IPR002205 (9.4%)" "DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (9.5%) Type II DNA Topoisomerases (9.5%) DNA topoisomerase, type IIA, domain A (9.4%)" LELYEKDYDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (20.5%) IPR002890 (20.5%) IPR051802 (20.5%)" "Alpha-2-macroglobulin (20.5%) Macroglobulin domain (20.5%) Alpha-2-macroglobulin-like (20.5%)" TGEGVEDLLEAVVNR Pseudomonadati Bacteria Pseudomonadati 3.6.5.0 (100%) Unknown (100%) GO:0045727 (17.2%) GO:0005886 (15.6%) "GO:0003924 (17.2%) GO:0005525 (17.2%) GO:0043022 (17.2%)" positive regulation of translation (17.2%) plasma membrane (15.6%) "GTPase activity (17.2%) GTP binding (17.2%) ribosome binding (17.2%)" "IPR000795 (10.8%) IPR005225 (10.8%) IPR006297 (10.8%)" "Translational (tr)-type GTP-binding domain (10.8%) Small GTP-binding domain (10.8%) Elongation factor 4 (10.8%)" ALADVVVLGYGTAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (3.3%) GO:0009279 (93.3%) GO:0015344 (3.3%) siderophore transmembrane transport (3.3%) cell outer membrane (93.3%) siderophore uptake transmembrane transporter activity (3.3%) "IPR012910 (11.9%) IPR023996 (11.9%) IPR023997 (11.9%)" "TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (11.9%)" VSVVTEPER Bacteria Bacteria 5.3.1.8 (100%) mannose-6-phosphate isomerase (100%) "GO:0005976 (25.4%) GO:0009298 (25.4%)" "GO:0004475 (25.4%) GO:0000166 (21.1%) GO:0004476 (1.4%)" "polysaccharide metabolic process (25.4%) GDP-mannose biosynthetic process (25.4%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (25.4%) nucleotide binding (21.1%) mannose-6-phosphate isomerase activity (1.4%)" "IPR001538 (17.8%) IPR005835 (17.8%) IPR051161 (17.8%)" "Mannose-6-phosphate isomerase, type II, C-terminal (17.8%) Nucleotidyl transferase domain (17.8%) Mannose-6-phosphate isomerase type 2 (17.8%)" LEFLGDAVLDAVVGDLVYQHFPGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.26.3 (100%) ribonuclease III (100%) "GO:0006364 (11.6%) GO:0010468 (11.6%) GO:0006397 (10.7%)" GO:0005737 (10.7%) "GO:0003725 (11.6%) GO:0004525 (11.6%) GO:0019843 (10.7%)" "rRNA processing (11.6%) regulation of gene expression (11.6%) mRNA processing (10.7%)" cytoplasm (10.7%) "double-stranded RNA binding (11.6%) ribonuclease III activity (11.6%) rRNA binding (10.7%)" "IPR000999 (25.2%) IPR011907 (25.2%) IPR014720 (25.2%)" "Ribonuclease III domain (25.2%) Ribonuclease III (25.2%) Double-stranded RNA-binding domain (25.2%)" NTTTEAVNLGFTGTATNPTNTSDYFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" AAQYLNALDKNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EEADEKATELLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25.3%) "GO:0005524 (25.3%) GO:0016887 (25.3%) GO:0015424 (24%)" plasma membrane (25.3%) "ATP binding (25.3%) ATP hydrolysis activity (25.3%) ABC-type amino acid transporter activity (24%)" "IPR003439 (17%) IPR003593 (17%) IPR017871 (17%)" "ABC transporter-like, ATP-binding domain (17%) AAA+ ATPase domain (17%) ABC transporter-like, conserved site (17%)" QMLANATGCSSLYSASLPSTPYTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.4%) GO:0022900 (14.4%) GO:0044281 (13.8%)" "GO:0005506 (14.4%) GO:0030976 (14.4%) GO:0051539 (14.4%)" "response to oxidative stress (14.4%) electron transport chain (14.4%) small molecule metabolic process (13.8%)" "iron ion binding (14.4%) thiamine pyrophosphate binding (14.4%) 4 iron, 4 sulfur cluster binding (14.4%)" "IPR002880 (7.7%) IPR011766 (7.7%) IPR011895 (7.7%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.7%) Thiamine pyrophosphate enzyme, TPP-binding (7.7%) Pyruvate-flavodoxin oxidoreductase (7.7%)" TFVATDEASFMLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (23.1%) IPR057601 (23.1%) IPR008969 (17.9%)" "TonB-dependent receptor-like (23.1%) TonB-dependent transporter Oar-like, beta-barrel domain (23.1%) Carboxypeptidase-like, regulatory domain superfamily (17.9%)" TQDLQFFKPDYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.267 (100%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (100%) GO:0051484 (23.5%) "GO:0030145 (23.5%) GO:0030604 (23.5%) GO:0070402 (23.5%)" isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process (23.5%) "manganese ion binding (23.5%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity (23.5%) NADPH binding (23.5%)" "IPR003821 (17.1%) IPR026877 (17.1%) IPR036169 (17.1%)" "1-deoxy-D-xylulose 5-phosphate reductoisomerase (17.1%) DXP reductoisomerase, C-terminal domain (17.1%) DXP reductoisomerase, C-terminal domain superfamily (17.1%)" ALLFDVDGVLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.- (100%) Phosphoric monoester hydrolases (100%) "GO:0008781 (34%) GO:0016788 (34%) GO:0046872 (32%)" "N-acylneuraminate cytidylyltransferase activity (34%) hydrolase activity, acting on ester bonds (34%) metal ion binding (32%)" "IPR010023 (21%) IPR050793 (21%) IPR023214 (19.8%)" "KdsC family (21%) CMP-NeuNAc synthase (21%) HAD superfamily (19.8%)" FVLNEVLEAGNFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) IPR039498 (100%) Uncharacterised nucleotidyltransferase (100%) YKWELATMGCR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.7%) GO:0009265 (16.7%)" GO:0031250 (16.7%) "GO:0004748 (16.7%) GO:0005524 (16.7%) GO:0008998 (16.7%)" "DNA replication (16.7%) 2'-deoxyribonucleotide biosynthetic process (16.7%)" anaerobic ribonucleoside-triphosphate reductase complex (16.7%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.7%) ATP binding (16.7%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.7%)" "IPR005144 (50%) IPR012833 (50%)" "ATP-cone domain (50%) Ribonucleoside-triphosphate reductase, anaerobic (50%)" FLYSDHDLFLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005524 (24.8%) GO:0016887 (24.8%) GO:0051082 (24.8%)" "ATP binding (24.8%) ATP hydrolysis activity (24.8%) unfolded protein binding (24.8%)" "IPR001404 (18%) IPR019805 (18%) IPR020575 (18%)" "Heat shock protein Hsp90 family (18%) Heat shock protein Hsp90, conserved site (18%) Heat shock protein Hsp90, N-terminal (18%)" TWTVAGSPELLGVEWKPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR054409 (50%)" "Immunoglobulin-like fold (50%) Amylopullulanase, X25 domain (50%)" FLEAASEVSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.7%) 6.3.4.16 (49.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.7%) carbamoyl-phosphate synthase (ammonia) (49.3%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" GWEFALSSQNLTGALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QLEDLKELLYAYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (51.1%) IPR029052 (48.9%)" "Fructose-1,6-bisphosphatase class 3 (51.1%) Metallo-dependent phosphatase-like (48.9%)" LYENVVR root "3.1.3.5 (48.6%) 6.1.1.2 (20%) 2.4.99.16 (5.7%)" "5'-nucleotidase (48.6%) tryptophan--tRNA ligase (20%) starch synthase (maltosyl-transferring) (5.7%)" "GO:0071709 (24.5%) GO:0000712 (3.8%) GO:0006196 (1.6%)" "GO:0009279 (24.3%) GO:0000794 (3.8%) GO:0016020 (3%)" "GO:0016887 (3.8%) GO:0003697 (3.3%) GO:0046872 (2.7%)" "membrane assembly (24.5%) resolution of meiotic recombination intermediates (3.8%) AMP catabolic process (1.6%)" "cell outer membrane (24.3%) condensed nuclear chromosome (3.8%) membrane (3%)" "ATP hydrolysis activity (3.8%) single-stranded DNA binding (3.3%) metal ion binding (2.7%)" "IPR010827 (16.1%) IPR034746 (16%) IPR023707 (15.2%)" "POTRA domain, BamA/TamA-like (16.1%) POTRA domain (16%) Outer membrane protein assembly factor BamA (15.2%)" EFDDEALHELAESLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0007059 (25%) GO:0045881 (25%)" GO:0005694 (25%) GO:0003677 (25%) "chromosome segregation (25%) positive regulation of sporulation resulting in formation of a cellular spore (25%)" chromosome (25%) DNA binding (25%) "IPR003115 (16.7%) IPR004437 (16.7%) IPR036086 (16.7%)" "ParB-like, N-terminal domain (16.7%) ParB/RepB/Spo0J partition protein (16.7%) ParB/Sulfiredoxin superfamily (16.7%)" RQGLFYATGLNEGNDVGSTYYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" GENGAPEALSFAVPFAELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" LMDVFEHHAPTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027848 (100%) Protein of unknown function DUF4494 (100%) SFNDDEEETDEEVAAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (50%) GO:0043565 (50%) regulation of DNA-templated transcription (50%) sequence-specific DNA binding (50%) "IPR000485 (12.5%) IPR011008 (12.5%) IPR011991 (12.5%)" "AsnC-type HTH domain (12.5%) Dimeric alpha-beta barrel (12.5%) ArsR-like helix-turn-helix domain (12.5%)" LTAAEQLKFLEELLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.7%) GO:0009986 (16.7%)" "GO:0000287 (16.7%) GO:0004634 (16.7%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.7%) cell surface (16.7%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%)" "IPR000941 (16.7%) IPR020809 (16.7%) IPR020810 (16.7%)" "Enolase (16.7%) Enolase, conserved site (16.7%) Enolase, C-terminal TIM barrel domain (16.7%)" VEEVLFTR root 2.8.1.7 (100%) cysteine desulfurase (100%) "GO:0006534 (26.3%) GO:0006629 (2%) GO:0033075 (1%)" "GO:0005829 (1%) GO:0016020 (1%)" "GO:0030170 (26.3%) GO:0031071 (26.3%) GO:0004497 (2%)" "cysteine metabolic process (26.3%) lipid metabolic process (2%) isoquinoline alkaloid biosynthetic process (1%)" "cytosol (1%) membrane (1%)" "pyridoxal phosphate binding (26.3%) cysteine desulfurase activity (26.3%) monooxygenase activity (2%)" "IPR000192 (12.9%) IPR010970 (12.9%) IPR015421 (12.9%)" "Aminotransferase class V domain (12.9%) Cysteine desulfurase, SufS (12.9%) Pyridoxal phosphate-dependent transferase, major domain (12.9%)" LEDYNLVR root "GO:0006351 (2.6%) GO:0006606 (2.6%) GO:0016070 (2.6%)" "GO:0009279 (28.2%) GO:0005634 (10.3%) GO:0005737 (5.1%)" "GO:0003677 (15.4%) GO:0003700 (12.8%) GO:0000981 (2.6%)" "DNA-templated transcription (2.6%) protein import into nucleus (2.6%) RNA metabolic process (2.6%)" "cell outer membrane (28.2%) nucleus (10.3%) cytoplasm (5.1%)" "DNA binding (15.4%) DNA-binding transcription factor activity (12.8%) DNA-binding transcription factor activity, RNA polymerase II-specific (2.6%)" "IPR011990 (12.9%) IPR012944 (12.9%) IPR033985 (12.9%)" "Tetratricopeptide-like helical domain superfamily (12.9%) RagB/SusD domain (12.9%) SusD-like, N-terminal (12.9%)" LYCAVSR root 3.6.5.0 (100%) Unknown (100%) "GO:0006412 (0.9%) GO:0006431 (0.9%) GO:0006644 (0.9%)" "GO:0009279 (38.2%) GO:0016020 (5.5%) GO:0005886 (3.6%)" "GO:0003677 (5.5%) GO:0004497 (4.5%) GO:0005506 (4.5%)" "translation (0.9%) methionyl-tRNA aminoacylation (0.9%) phospholipid metabolic process (0.9%)" "cell outer membrane (38.2%) membrane (5.5%) plasma membrane (3.6%)" "DNA binding (5.5%) monooxygenase activity (4.5%) iron ion binding (4.5%)" "IPR033985 (17.6%) IPR011990 (17.2%) IPR012944 (17.2%)" "SusD-like, N-terminal (17.6%) Tetratricopeptide-like helical domain superfamily (17.2%) RagB/SusD domain (17.2%)" TGDGAGLMLQLPHEFLLLQGLPVPEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.6%) GO:0019676 (19.6%)" "GO:0051538 (19.6%) GO:0046872 (19.3%) GO:0004355 (10.3%)" "glutamate biosynthetic process (19.6%) ammonia assimilation cycle (19.6%)" "3 iron, 4 sulfur cluster binding (19.6%) metal ion binding (19.3%) glutamate synthase (NADPH) activity (10.3%)" "IPR017932 (12.8%) IPR050711 (12.8%) IPR029055 (12.6%)" "Glutamine amidotransferase type 2 domain (12.8%) Electron transfer and nitrogen metabolism enzyme (12.8%) Nucleophile aminohydrolases, N-terminal (12.6%)" TLLNSDQMAAYGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LTDDFGR root "4.1.99.22 (46.5%) 2.7.7.6 (45.7%) 3.2.2.27 (2.3%)" "GTP 3',8-cyclase (46.5%) DNA-directed RNA polymerase (45.7%) uracil-DNA glycosylase (2.3%)" "GO:0006351 (5.3%) GO:0006777 (4.5%) GO:0006308 (1%)" "GO:0000428 (5.3%) GO:0016020 (2.7%) GO:0005737 (2.4%)" "GO:0008270 (5.6%) GO:0003677 (5.5%) GO:0003899 (5.2%)" "DNA-templated transcription (5.3%) Mo-molybdopterin cofactor biosynthetic process (4.5%) DNA catabolic process (1%)" "DNA-directed RNA polymerase complex (5.3%) membrane (2.7%) cytoplasm (2.4%)" "zinc ion binding (5.6%) DNA binding (5.5%) DNA-directed RNA polymerase activity (5.2%)" "IPR000722 (3.7%) IPR006592 (3.7%) IPR007066 (3.7%)" "RNA polymerase, alpha subunit (3.7%) RNA polymerase, N-terminal (3.7%) RNA polymerase Rpb1, domain 3 (3.7%)" NLSPGVFR root "2.1.1.173 (50%) 2.1.1.- (30%) 2.1.1.171 (10%)" "23S rRNA (guanine(2445)-N(2))-methyltransferase (50%) Methyltransferases (30%) 16S rRNA (guanine(966)-N(2))-methyltransferase (10%)" "GO:0016102 (0.6%) GO:0043066 (0.6%) GO:0050821 (0.6%)" "GO:0005737 (0.6%) GO:0005615 (0.3%) GO:0016020 (0.3%)" "GO:0070043 (30.8%) GO:0003723 (30.5%) GO:0008990 (29.4%)" "diterpenoid biosynthetic process (0.6%) negative regulation of apoptotic process (0.6%) protein stabilization (0.6%)" "cytoplasm (0.6%) extracellular space (0.3%) membrane (0.3%)" "rRNA (guanine-N7-)-methyltransferase activity (30.8%) RNA binding (30.5%) rRNA (guanine-N2-)-methyltransferase activity (29.4%)" "IPR000241 (16.1%) IPR002052 (15.9%) IPR004114 (15.9%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.1%) DNA methylase, N-6 adenine-specific, conserved site (15.9%) THUMP domain (15.9%)" YAEGLLAVK root "GO:0005975 (0.2%) GO:0030259 (0.2%)" GO:0005886 (49.6%) "GO:0005283 (49.6%) GO:0016906 (0.2%)" "carbohydrate metabolic process (0.2%) obsolete lipid glycosylation (0.2%)" plasma membrane (49.6%) "amino acid:sodium symporter activity (49.6%) sterol 3-beta-glucosyltransferase activity (0.2%)" "IPR001463 (97.5%) IPR002213 (0.5%) IPR004276 (0.5%)" "Sodium:alanine symporter (97.5%) UDP-glucuronosyl/UDP-glucosyltransferase (0.5%) Glycosyltransferase family 28, N-terminal domain (0.5%)" YDANGNPTVLFDAPLGESNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) SSLTDGLVPADENDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.2%) GO:0016787 (50.8%) carbohydrate metabolic process (49.2%) hydrolase activity (50.8%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" GADAEANNEALLNYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (44.3%) "GO:0004650 (44.3%) GO:0004557 (11.5%)" carbohydrate metabolic process (44.3%) "polygalacturonase activity (44.3%) alpha-galactosidase activity (11.5%)" "IPR000743 (13%) IPR006626 (13%) IPR010905 (13%)" "Glycoside hydrolase, family 28 (13%) Parallel beta-helix repeat (13%) Glycosyl hydrolase, family 88 (13%)" LLTLTEGMTSEGVKDYSGAELLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.7%) IPR007121 (7.7%) IPR007641 (7.7%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.7%) RNA polymerase, beta subunit, conserved site (7.7%) RNA polymerase Rpb2, domain 7 (7.7%)" VLLEDTPEGER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004519 (100%) endonuclease activity (100%) EGYSFEEAYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.1%) "GO:0004470 (16.8%) GO:0016616 (16.8%) GO:0016746 (16.8%)" malate metabolic process (16.1%) "malic enzyme activity (16.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.8%) acyltransferase activity (16.8%)" "IPR002505 (9.3%) IPR012301 (9.3%) IPR012302 (9.3%)" "Phosphate acetyl/butaryl transferase (9.3%) Malic enzyme, N-terminal domain (9.3%) Malic enzyme, NAD-binding (9.3%)" EYQQNVEQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) LVSALLLQHENSLVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021670 (100%) Protein of unknown function DUF3256 (100%) VHQALALCNDFDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (32%) GO:0046677 (31%)" GO:0016020 (5%) GO:0008800 (32%) "beta-lactam antibiotic catabolic process (32%) response to antibiotic (31%)" membrane (5%) beta-lactamase activity (32%) "IPR045155 (25.8%) IPR000871 (25%) IPR023650 (25%)" "Beta-lactamase class A, catalytic domain (25.8%) Beta-lactamase, class-A (25%) Beta-lactamase, class-A active site (25%)" LGLGTAYLMGFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.4.-.- (50%) 2.4.1.- (50%)" "Glycosyltransferases (50%) Hexosyltransferases (50%)" GO:0009247 (33.3%) GO:0016020 (33.3%) GO:0004582 (33.3%) glycolipid biosynthetic process (33.3%) membrane (33.3%) dolichyl-phosphate beta-D-mannosyltransferase activity (33.3%) "IPR001173 (34.1%) IPR039528 (34.1%) IPR029044 (31.7%)" "Glycosyltransferase 2-like (34.1%) DPM1-like (34.1%) Nucleotide-diphospho-sugar transferases (31.7%)" DNAEQLLNAALQQEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR011990 (31.8%) IPR013105 (31.8%) IPR019734 (31.8%)" "Tetratricopeptide-like helical domain superfamily (31.8%) Tetratricopeptide repeat 2 (31.8%) Tetratricopeptide repeat (31.8%)" TGYFLQK root "2.7.13.3 (42.9%) 2.1.1.- (14.3%) 2.4.99.28 (14.3%)" "histidine kinase (42.9%) Methyltransferases (14.3%) peptidoglycan glycosyltransferase (14.3%)" "GO:0045214 (6.2%) GO:0007155 (5.9%) GO:0006457 (4%)" "GO:0009279 (22.3%) GO:0031430 (6.2%) GO:0032982 (5.6%)" "GO:0003779 (5%) GO:0051082 (4%) GO:0008270 (0.9%)" "sarcomere organization (6.2%) cell adhesion (5.9%) protein folding (4%)" "cell outer membrane (22.3%) M band (6.2%) myosin filament (5.6%)" "actin binding (5%) unfolded protein binding (4%) zinc ion binding (0.9%)" "IPR012944 (12.2%) IPR033985 (12%) IPR011990 (11.6%)" "RagB/SusD domain (12.2%) SusD-like, N-terminal (12%) Tetratricopeptide-like helical domain superfamily (11.6%)" LWGGQSLLAGNLLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001684 (50%) IPR018261 (50%)" "Large ribosomal subunit protein bL27 (50%) Large ribosomal subunit protein bL27, conserved site (50%)" VPTLDVSVVDLTVNLK Bacteria Bacteria 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) "GO:0006006 (23.7%) GO:0006096 (3.4%)" GO:0005829 (1.7%) "GO:0050661 (23.7%) GO:0051287 (23.7%) GO:0004365 (11.9%)" "glucose metabolic process (23.7%) glycolytic process (3.4%)" cytosol (1.7%) "NADP binding (23.7%) NAD binding (23.7%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (11.9%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" AGYFVEDDWMLLGQVEYNHSGLEGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR036709 (50%) IPR027385 (37.5%) IPR011250 (12.5%)" "Autotransporter beta-domain superfamily (50%) Outer membrane protein, beta-barrel domain (37.5%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (12.5%)" DLPTEVAR root "5.2.1.8 (75%) 2.5.1.3 (7.1%) 1.3.1.104 (3.6%)" "peptidylprolyl isomerase (75%) thiamine phosphate synthase (7.1%) enoyl-[acyl-carrier-protein] reductase (3.6%)" "GO:0006351 (16.5%) GO:0009228 (1.1%) GO:0009229 (1.1%)" "GO:0005737 (1.6%) GO:0005829 (0.5%) GO:0005886 (0.5%)" "GO:0003755 (33%) GO:0003700 (16.5%) GO:0043565 (16.5%)" "DNA-templated transcription (16.5%) thiamine biosynthetic process (1.1%) thiamine diphosphate biosynthetic process (1.1%)" "cytoplasm (1.6%) cytosol (0.5%) plasma membrane (0.5%)" "peptidyl-prolyl cis-trans isomerase activity (33%) DNA-binding transcription factor activity (16.5%) sequence-specific DNA binding (16.5%)" "IPR000297 (14.3%) IPR050280 (14.1%) IPR046357 (13.6%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (14.3%) Outer Membrane Protein Chaperone SurA (14.1%) Peptidyl-prolyl cis-trans isomerase domain superfamily (13.6%)" FLGTLNATNLFLGYKGEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (25%) "GO:0009279 (25%) GO:0046930 (25%)" GO:0015288 (25%) monoatomic ion transport (25%) "cell outer membrane (25%) pore complex (25%)" porin activity (25%) "IPR006664 (19.7%) IPR006665 (19.7%) IPR011250 (19.7%)" "Outer membrane protein, bacterial (19.7%) OmpA-like domain (19.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (19.7%)" NLQDLAEYFMNHSDYPLVSDEAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.4%) GO:0005829 (16.4%) "GO:0003677 (16.4%) GO:0005524 (16.4%) GO:0043138 (16.4%)" recombinational repair (16.4%) cytosol (16.4%) "DNA binding (16.4%) ATP binding (16.4%) 3'-5' DNA helicase activity (16.4%)" "IPR000212 (20.3%) IPR014016 (20.3%) IPR014017 (20.3%)" "DNA helicase, UvrD/REP type (20.3%) UvrD-like helicase, ATP-binding domain (20.3%) UvrD-like DNA helicase, C-terminal (20.3%)" SWRGDDTHVFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) LVELGLTPNDEAYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0046872 (50%)" "hydrolase activity (50%) metal ion binding (50%)" IPR039461 (100%) Peptidase family M49 (100%) ADAVQTSTDFGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" LALYFTDEWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.1%) GO:0009279 (35.7%) GO:0015344 (32.1%) siderophore transmembrane transport (32.1%) cell outer membrane (35.7%) siderophore uptake transmembrane transporter activity (32.1%) "IPR036942 (50.9%) IPR039426 (47.4%) IPR057601 (1.8%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50.9%) TonB-dependent receptor-like (47.4%) TonB-dependent transporter Oar-like, beta-barrel domain (1.8%)" TNNGLYYQWENFANYLTTLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" LADYVLNGNVEDVVPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (16.7%) IPR014729 (16.7%) IPR014730 (16.7%)" "Electron transfer flavoprotein alpha subunit/FixB (16.7%) Rossmann-like alpha/beta/alpha sandwich fold (16.7%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (16.7%)" ELNVTFNGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" ELADSTDWK Pseudomonadati Bacteria Pseudomonadati IPR007139 (100%) Protein of unknown function DUF349 (100%) METPSLYDSEQQLVSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.9%) IPR004634 (16.9%) IPR004635 (16.9%)" "Peptidase S49 (16.9%) Peptidase S49, protease IV (16.9%) Peptidase S49, SppA (16.9%)" QLLANYADVPENLLQALVESNR Bacteria Bacteria 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (26.8%) GO:0006065 (14.7%) GO:0006072 (2.9%)" "GO:0051287 (27.7%) GO:0003979 (26.8%) GO:0016616 (0.9%)" "polysaccharide biosynthetic process (26.8%) UDP-glucuronate biosynthetic process (14.7%) glycerol-3-phosphate metabolic process (2.9%)" "NAD binding (27.7%) UDP-glucose 6-dehydrogenase activity (26.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (0.9%)" "IPR014026 (11.2%) IPR001732 (11%) IPR014027 (11%)" "UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.2%) UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (11%)" TTPLWGR root "2.4.1.301 (60%) 3.2.1.- (40%)" "2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase (60%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (40%)" "GO:0006412 (1.3%) GO:0006013 (0.2%) GO:0006865 (0.2%)" "GO:0005886 (9.1%) GO:0005762 (1.3%) GO:0016020 (0.6%)" "GO:0046872 (21.9%) GO:0009055 (17.1%) GO:0020037 (17.1%)" "translation (1.3%) mannose metabolic process (0.2%) amino acid transport (0.2%)" "plasma membrane (9.1%) mitochondrial large ribosomal subunit (1.3%) membrane (0.6%)" "metal ion binding (21.9%) electron transfer activity (17.1%) heme binding (17.1%)" "IPR010538 (17.1%) IPR036909 (16.6%) IPR051395 (14.8%)" "Di-haem oxidoreductase, putative peroxidase (17.1%) Cytochrome c-like domain superfamily (16.6%) Cytochrome c-dependent Peroxidase and MauG (14.8%)" VASELPYLYQGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales YTGDPDCSLPEQLAVQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0003755 (90.9%) GO:0016853 (9.1%)" "peptidyl-prolyl cis-trans isomerase activity (90.9%) isomerase activity (9.1%)" "IPR050280 (27.5%) IPR000297 (25%) IPR027304 (25%)" "Outer Membrane Protein Chaperone SurA (27.5%) Peptidyl-prolyl cis-trans isomerase, PpiC-type (25%) Trigger factor/SurA domain superfamily (25%)" LLDNLTALWGEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0003676 (100%) nucleic acid binding (100%) "IPR009362 (27.3%) IPR041527 (27.3%) IPR053148 (27.3%)" "YhcG PDDEXK nuclease domain (27.3%) YhcG, N-terminal (27.3%) PD-(D/E)XK-like domain-containing protein (27.3%)" ANLLFSGQSVDETTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" NLYMPNSLVTLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026906 (33.3%) IPR032675 (33.3%) IPR053139 (33.3%)" "BspA-type LRR region (33.3%) Leucine-rich repeat domain superfamily (33.3%) Putative surface bspA-like protein (33.3%)" VYYLDTLEYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR006598 (50%) IPR051091 (50%)" "Glycosyl transferase CAP10 domain (50%) Protein O-Glucosyltransferase/Glycosyltransferase 90 (50%)" RVNSLAENNPMLGHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" VYAPESYGDLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.26.11 (100%) ribonuclease Z (100%) "GO:0008270 (50%) GO:0042781 (50%)" "zinc ion binding (50%) 3'-tRNA processing endoribonuclease activity (50%)" "IPR001279 (33.7%) IPR013471 (33.7%) IPR036866 (32.5%)" "Metallo-beta-lactamase (33.7%) Ribonuclease Z/BN (33.7%) Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (32.5%)" FSLTDGLAANTLSDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (10.9%) "GO:0000155 (30%) GO:0003700 (29.1%) GO:0043565 (29.1%)" membrane (10.9%) "phosphorelay sensor kinase activity (30%) DNA-binding transcription factor activity (29.1%) sequence-specific DNA binding (29.1%)" "IPR015943 (11.8%) IPR011110 (11.1%) IPR001789 (10.8%)" "WD40/YVTN repeat-like-containing domain superfamily (11.8%) Two component regulator propeller (11.1%) Signal transduction response regulator, receiver domain (10.8%)" AHEVLDNYMESNHHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0045892 (16.7%) GO:1900376 (16.7%)" GO:0005829 (16.7%) "GO:0000976 (16.7%) GO:0003700 (16.7%) GO:0008270 (16.7%)" "negative regulation of DNA-templated transcription (16.7%) regulation of secondary metabolite biosynthetic process (16.7%)" cytosol (16.7%) "transcription cis-regulatory region binding (16.7%) DNA-binding transcription factor activity (16.7%) zinc ion binding (16.7%)" "IPR002481 (27.6%) IPR036388 (24.1%) IPR036390 (24.1%)" "Ferric-uptake regulator (27.6%) Winged helix-like DNA-binding domain superfamily (24.1%) Winged helix DNA-binding domain superfamily (24.1%)" HVVQLVPDGPTQLYLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.7%) IPR050067 (14.7%) IPR004430 (14.1%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.7%) Isopropylmalate dehydratase and related enzymes (14.7%) 3-isopropylmalate dehydratase, large subunit (14.1%)" VGEWVLAVGNPFGLNNTVTAGLLSAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.21.107 (80%) 3.4.21.- (20%)" "peptidase Do (80%) Serine endopeptidases (20%)" GO:0006508 (49.3%) GO:0016020 (1.4%) GO:0004252 (49.3%) proteolysis (49.3%) membrane (1.4%) serine-type endopeptidase activity (49.3%) "IPR001478 (18.5%) IPR001940 (17.9%) IPR009003 (17.9%)" "PDZ domain (18.5%) Peptidase S1C (17.9%) Peptidase S1, PA clan (17.9%)" YTYFASK root "1.11.1.1 (68.4%) 1.14.13.81 (15.8%) 2.7.7.48 (5.3%)" "NADH peroxidase (68.4%) magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (15.8%) RNA-directed RNA polymerase (5.3%)" "GO:0008535 (4.3%) GO:0045892 (0.6%) GO:0006537 (0.3%)" "GO:0005886 (4.3%) GO:0000139 (0.1%) GO:0005829 (0.1%)" "GO:0016491 (27%) GO:0005506 (25.8%) GO:0000976 (12.3%)" "respiratory chain complex IV assembly (4.3%) negative regulation of DNA-templated transcription (0.6%) glutamate biosynthetic process (0.3%)" "plasma membrane (4.3%) Golgi membrane (0.1%) cytosol (0.1%)" "oxidoreductase activity (27%) iron ion binding (25.8%) transcription cis-regulatory region binding (12.3%)" "IPR003251 (10.7%) IPR009040 (10.7%) IPR052364 (10.7%)" "Rubrerythrin, diiron-binding domain (10.7%) Ferritin-like diiron domain (10.7%) Rubrerythrin (10.7%)" GDLEVLFDNTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" KSSFTGSAGVVDADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LNFFVNTAHNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20.6%) "GO:0000155 (24.7%) GO:0003700 (23.5%) GO:0043565 (23.5%)" membrane (20.6%) "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (23.5%) sequence-specific DNA binding (23.5%)" "IPR003594 (6.6%) IPR003661 (6.6%) IPR005467 (6.6%)" "Histidine kinase/HSP90-like ATPase domain (6.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.6%) Histidine kinase domain (6.6%)" SLESFYQELGR Pseudomonadati Bacteria Pseudomonadati "5.6.2.4 (93.3%) 3.6.4.12 (6.3%) 3.6.1.- (0.4%)" "DNA 3'-5' helicase (93.3%) DNA helicase (6.3%) In phosphorus-containing anhydrides (0.4%)" "GO:0006260 (8.3%) GO:0006281 (8.3%) GO:0006310 (8.3%)" "GO:0005737 (8.3%) GO:0030894 (8.3%) GO:0043590 (8.3%)" "GO:0016787 (8.4%) GO:0003677 (8.3%) GO:0005524 (8.3%)" "DNA replication (8.3%) DNA repair (8.3%) DNA recombination (8.3%)" "cytoplasm (8.3%) replisome (8.3%) bacterial nucleoid (8.3%)" "hydrolase activity (8.4%) DNA binding (8.3%) ATP binding (8.3%)" "IPR001650 (7.7%) IPR004589 (7.7%) IPR011545 (7.7%)" "Helicase, C-terminal domain-like (7.7%) DNA helicase, ATP-dependent, RecQ type (7.7%) DEAD/DEAH-box helicase domain (7.7%)" NDLAVNPEDYWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (10%) GO:0009279 (90%) iron ion transport (10%) cell outer membrane (90%) "IPR012910 (14.3%) IPR023996 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" ELDRLMGLQGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (16.4%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (16.4%)" "IPR015939 (14.5%) IPR030664 (14.5%) IPR037099 (14.5%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.5%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.5%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (14.5%)" LVSSPNWSK root 3.2.1.1 (100%) alpha-amylase (100%) "GO:0005975 (31.6%) GO:0016192 (5.3%) GO:1905515 (5.3%)" "GO:0004556 (28.9%) GO:0043169 (28.9%)" "carbohydrate metabolic process (31.6%) vesicle-mediated transport (5.3%) non-motile cilium assembly (5.3%)" "alpha-amylase activity (28.9%) cation binding (28.9%)" "IPR006047 (31.6%) IPR006046 (28.9%) IPR017853 (28.9%)" "Glycosyl hydrolase family 13, catalytic domain (31.6%) Alpha amylase (28.9%) Glycoside hydrolase superfamily (28.9%)" VESDLLGELKVPAEALYGVQTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.3.1.1 (100%) aspartate ammonia-lyase (100%) "GO:0006099 (25%) GO:0006531 (25%)" GO:0005829 (25%) GO:0008797 (25%) "tricarboxylic acid cycle (25%) aspartate metabolic process (25%)" cytosol (25%) aspartate ammonia-lyase activity (25%) "IPR000362 (14.3%) IPR008948 (14.3%) IPR018951 (14.3%)" "Fumarate lyase family (14.3%) L-Aspartase-like (14.3%) Fumarase C, C-terminal (14.3%)" YSQFLSQQQLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri RPDDPFPFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006281 (25%) GO:0006310 (25%)" "GO:0003676 (25%) GO:0008409 (25%)" "DNA repair (25%) DNA recombination (25%)" "nucleic acid binding (25%) 5'-3' exonuclease activity (25%)" "IPR001667 (16.7%) IPR003156 (16.7%) IPR004610 (16.7%)" "DDH domain (16.7%) DHHA1 domain (16.7%) Bacterial RecJ exonuclease (16.7%)" TFLTEGNSR root 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0043041 (1.8%) GO:0044550 (1.8%)" GO:0005737 (1.8%) "GO:0016757 (51.8%) GO:0016740 (28.6%) GO:0004044 (10.7%)" "amino acid activation for nonribosomal peptide biosynthetic process (1.8%) secondary metabolite biosynthetic process (1.8%)" cytoplasm (1.8%) "glycosyltransferase activity (51.8%) transferase activity (28.6%) amidophosphoribosyltransferase activity (10.7%)" "IPR017932 (25%) IPR029057 (25%) IPR029055 (24.7%)" "Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%) Nucleophile aminohydrolases, N-terminal (24.7%)" HDDDQPGDLSAATATAALAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (25%) GO:0071555 (25%)" "GO:0016758 (25%) GO:0016798 (25%)" "carbohydrate metabolic process (25%) cell wall organization (25%)" "hexosyltransferase activity (25%) hydrolase activity, acting on glycosyl bonds (25%)" "IPR007184 (34.5%) IPR028583 (34.5%) IPR023296 (30.9%)" "Mannoside phosphorylase (34.5%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (34.5%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (30.9%)" GHTLVLPR root "2.1.1.- (72.7%) 2.7.7.53 (9.1%) 3.6.1.17 (9.1%)" "Methyltransferases (72.7%) ATP adenylyltransferase (9.1%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (9.1%)" "GO:0009117 (40.3%) GO:0032259 (0.7%) GO:0009396 (0.5%)" "GO:0005829 (1.8%) GO:0016020 (0.5%)" "GO:0003824 (36.3%) GO:0016787 (6.7%) GO:0005524 (2.8%)" "nucleotide metabolic process (40.3%) methylation (0.7%) folic acid-containing compound biosynthetic process (0.5%)" "cytosol (1.8%) membrane (0.5%)" "catalytic activity (36.3%) hydrolase activity (6.7%) ATP binding (2.8%)" "IPR011146 (24.5%) IPR036265 (24.4%) IPR001310 (23.5%)" "HIT-like domain (24.5%) HIT-like superfamily (24.4%) Histidine triad (HIT) protein (23.5%)" SHLDLLQVDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.5%) GO:0034605 (12.5%)" GO:0005737 (12.5%) "GO:0004176 (12.5%) GO:0004252 (12.5%) GO:0005524 (12.5%)" "protein quality control for misfolded or incompletely synthesized proteins (12.5%) cellular response to heat (12.5%)" cytoplasm (12.5%) "ATP-dependent peptidase activity (12.5%) serine-type endopeptidase activity (12.5%) ATP binding (12.5%)" "IPR003111 (7.4%) IPR003593 (7.4%) IPR003959 (7.4%)" "Lon protease, N-terminal domain (7.4%) AAA+ ATPase domain (7.4%) ATPase, AAA-type, core (7.4%)" LSGVWDAEYGLLEDANQLLEGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YEENDLLKGDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.7%) GO:0043335 (15.7%) GO:0051083 (15.7%)" GO:0005737 (6%) "GO:0003755 (15.7%) GO:0043022 (15.7%) GO:0044183 (15.7%)" "protein transport (15.7%) protein unfolding (15.7%) 'de novo' cotranslational protein folding (15.7%)" cytoplasm (6%) "peptidyl-prolyl cis-trans isomerase activity (15.7%) ribosome binding (15.7%) protein folding chaperone (15.7%)" "IPR005215 (19%) IPR008881 (19%) IPR027304 (18.2%)" "Trigger factor (19%) Trigger factor, ribosome-binding, bacterial (19%) Trigger factor/SurA domain superfamily (18.2%)" LRFETLQLHVGQENPDPATDAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.2%) IPR006235 (17.2%) IPR054542 (17.2%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.2%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.2%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (17.2%)" SLYQFLDHTPEDCLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR050306 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) PfkB Carbohydrate Kinase (33.3%)" NGYDAPFVWTMPVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (56.3%) IPR042278 (43.8%)" "Fimbrillin-like 1 (56.3%) Fimbrillin-like 1, N-terminal (43.8%)" SVPSVPSVACSTAEALAWDASFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25.1%) GO:0005829 (25.1%) "GO:0004066 (25.1%) GO:0005524 (24.6%)" obsolete asparagine biosynthetic process (25.1%) cytosol (25.1%) "asparagine synthase (glutamine-hydrolyzing) activity (25.1%) ATP binding (24.6%)" "IPR050795 (14.6%) IPR001962 (14.3%) IPR006426 (14.3%)" "Asparagine Synthetase (14.6%) Asparagine synthase (14.3%) Asparagine synthase, glutamine-hydrolyzing (14.3%)" AADKDLQFVLLTGVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR012547 (50%) IPR018631 (50%)" "PD-(D/E)XK nuclease superfamily 9 (50%) AAA-ATPase-like domain (50%)" NLMAFWFDKGVDGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.16 (100%) maltose alpha-D-glucosyltransferase (100%) "GO:0009313 (48.8%) GO:0005975 (1.2%)" "GO:0004556 (48.8%) GO:0047471 (1.2%)" "oligosaccharide catabolic process (48.8%) carbohydrate metabolic process (1.2%)" "alpha-amylase activity (48.8%) maltose alpha-D-glucosyltransferase activity (1.2%)" "IPR006047 (26.5%) IPR017853 (25.3%) IPR045857 (25.3%)" "Glycosyl hydrolase family 13, catalytic domain (26.5%) Glycoside hydrolase superfamily (25.3%) Oligo-1,6-glucosidase, domain 2 (25.3%)" GVPLKDLMDTGEELDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.85 (100%) diadenylate cyclase (100%) GO:0006171 (20%) GO:0005886 (20%) "GO:0004016 (20%) GO:0005524 (20%) GO:0106408 (16.4%)" cAMP biosynthetic process (20%) plasma membrane (20%) "adenylate cyclase activity (20%) ATP binding (20%) diadenylate cyclase activity (16.4%)" "IPR003390 (16.7%) IPR014046 (16.7%) IPR034701 (16.7%)" "DNA integrity scanning protein, DisA, N-terminal (16.7%) Diadenylate cyclase (16.7%) Diadenylate cyclase CdaA (16.7%)" AANLLPVVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR003399 (50%) IPR052336 (50%)" "Mce/MlaD (50%) MlaD Inter-membrane Phospholipid Transporter (50%)" NGLQEVLVEGWNEGWEDWFGHQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.2%) GO:0016787 (48.8%)" "carbohydrate binding (51.2%) hydrolase activity (48.8%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" LVNLNLFK root "2.7.13.3 (68%) 2.5.1.75 (30%) 5.4.2.3 (2%)" "histidine kinase (68%) tRNA dimethylallyltransferase (30%) phosphoacetylglucosamine mutase (2%)" "GO:0006400 (5.1%) GO:0006270 (2.7%) GO:0007095 (2.7%)" "GO:0016020 (21.2%) GO:0005634 (1%) GO:0005856 (1%)" "GO:0000155 (11.6%) GO:0003700 (11.6%) GO:0043565 (11.6%)" "tRNA modification (5.1%) DNA replication initiation (2.7%) mitotic G2 DNA damage checkpoint signaling (2.7%)" "membrane (21.2%) nucleus (1%) cytoskeleton (1%)" "phosphorelay sensor kinase activity (11.6%) DNA-binding transcription factor activity (11.6%) sequence-specific DNA binding (11.6%)" "IPR001789 (5.1%) IPR003594 (5.1%) IPR003661 (5.1%)" "Signal transduction response regulator, receiver domain (5.1%) Histidine kinase/HSP90-like ATPase domain (5.1%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (5.1%)" NYVCNLYTLDNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" VLVEPTTR root "2.1.1.198 (50%) 6.1.1.6 (50%)" "16S rRNA (cytidine(1402)-2'-O)-methyltransferase (50%) lysine--tRNA ligase (50%)" "GO:0034605 (15.6%) GO:0006508 (15.2%) GO:0033539 (0.9%)" "GO:0005737 (16.1%) GO:0008537 (0.9%) GO:0016020 (0.5%)" "GO:0005524 (15.6%) GO:0016887 (15.6%) GO:0008233 (15.2%)" "cellular response to heat (15.6%) proteolysis (15.2%) fatty acid beta-oxidation using acyl-CoA dehydrogenase (0.9%)" "cytoplasm (16.1%) proteasome activator complex (0.9%) membrane (0.5%)" "ATP binding (15.6%) ATP hydrolysis activity (15.6%) peptidase activity (15.2%)" "IPR001943 (8.3%) IPR003593 (8.3%) IPR003959 (8.3%)" "UVR domain (8.3%) AAA+ ATPase domain (8.3%) ATPase, AAA-type, core (8.3%)" LPVFNGSLECEFRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.- (66.7%) 2.1.1.173 (33.3%)" "Methyltransferases (66.7%) 23S rRNA (guanine(2445)-N(2))-methyltransferase (33.3%)" "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.6%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.6%)" "IPR000241 (17.2%) IPR002052 (17.2%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.2%) DNA methylase, N-6 adenine-specific, conserved site (17.2%) THUMP domain (16.8%)" FHADASADYQNTFDAHSLYSQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" NTSALPAVCGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0051536 (49.6%) GO:0016491 (45.5%) GO:0004355 (4.9%)" "iron-sulfur cluster binding (49.6%) oxidoreductase activity (45.5%) glutamate synthase (NADPH) activity (4.9%)" "IPR023753 (11.4%) IPR028261 (11.4%) IPR006004 (11.2%)" "FAD/NAD(P)-binding domain (11.4%) Dihydroprymidine dehydrogenase domain II (11.4%) Sulfide dehydrogenase subunit alpha-like (11.2%)" LNVELGEKNEEMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20%) "GO:0000155 (20%) GO:0003700 (20%) GO:0005524 (20%)" membrane (20%) "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR001789 (7.7%) IPR003594 (7.7%) IPR003661 (7.7%)" "Signal transduction response regulator, receiver domain (7.7%) Histidine kinase/HSP90-like ATPase domain (7.7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.7%)" GLHLDANEVFVNDGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (33.3%) "GO:0010285 (33.3%) GO:0030170 (33.3%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (33.3%) "L,L-diaminopimelate aminotransferase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (21.4%) IPR019942 (21.4%) IPR015421 (19%)" "Aminotransferase, class I/classII, large domain (21.4%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21.4%) Pyridoxal phosphate-dependent transferase, major domain (19%)" FGSDQWQSVSFNLFSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (34.4%) IPR020845 (34.4%) IPR042099 (31.1%)" "AMP-dependent synthetase/ligase domain (34.4%) AMP-binding, conserved site (34.4%) ANL, N-terminal domain (31.1%)" FTPALNADGSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" HGNYAATSVSGASNVLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.18 (100%) anthranilate phosphoribosyltransferase (100%) GO:0000162 (25%) GO:0005829 (25%) "GO:0000287 (25%) GO:0004048 (25%)" L-tryptophan biosynthetic process (25%) cytosol (25%) "magnesium ion binding (25%) anthranilate phosphoribosyltransferase activity (25%)" "IPR000312 (20.3%) IPR005940 (20.3%) IPR017459 (20.3%)" "Glycosyl transferase, family 3 (20.3%) Anthranilate phosphoribosyl transferase (20.3%) Glycosyl transferase family 3, N-terminal domain (20.3%)" YDEYVVLR root "GO:0006952 (1%) GO:0051707 (1%)" "GO:0005524 (48%) GO:0016887 (47%) GO:0003676 (1%)" "defense response (1%) response to other organism (1%)" "ATP binding (48%) ATP hydrolysis activity (47%) nucleic acid binding (1%)" "IPR003439 (16.2%) IPR027417 (16.2%) IPR032781 (16.2%)" "ABC transporter-like, ATP-binding domain (16.2%) P-loop containing nucleoside triphosphate hydrolase (16.2%) ABC-transporter extension domain (16.2%)" LAGVDVQTGGGQPGSGAQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.8%) IPR039426 (13.8%) IPR000531 (12.8%)" "TonB-dependent receptor, plug domain (13.8%) TonB-dependent receptor-like (13.8%) TonB-dependent receptor-like, beta-barrel (12.8%)" LEHLSALLK root "2.7.1.- (25%) 2.7.13.3 (25%) 5.4.2.12 (25%)" "Phosphotransferases with an alcohol group as acceptor (25%) histidine kinase (25%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (25%)" "GO:0006298 (9.6%) GO:0006007 (0.3%) GO:0006096 (0.3%)" "GO:0005829 (9.8%) GO:0016020 (9.3%) GO:0071013 (1.3%)" "GO:0000976 (16.3%) GO:0003700 (16.3%) GO:0005524 (9.6%)" "mismatch repair (9.6%) glucose catabolic process (0.3%) glycolytic process (0.3%)" "cytosol (9.8%) membrane (9.3%) catalytic step 2 spliceosome (1.3%)" "transcription cis-regulatory region binding (16.3%) DNA-binding transcription factor activity (16.3%) ATP binding (9.6%)" "IPR001647 (15.6%) IPR009057 (15.6%) IPR050109 (15.3%)" "DNA-binding HTH domain, TetR-type (15.6%) Homedomain-like superfamily (15.6%) HTH-type, TetR-like transcriptional regulator (15.3%)" GNLNYFTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.9%) IPR029483 (14.9%) IPR029486 (14.9%)" "Glycosyl-hydrolase 97, catalytic domain (14.9%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.9%) Glycosyl-hydrolase 97, N-terminal domain (14.9%)" TVDDLDGALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.4%) GO:0005829 (16.4%) "GO:0003677 (16.4%) GO:0004527 (16.4%) GO:0005524 (16.4%)" recombinational repair (16.4%) cytosol (16.4%) "DNA binding (16.4%) exonuclease activity (16.4%) ATP binding (16.4%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" TELEDLSFR root "2.7.6.5 (61.9%) 3.1.7.2 (38.1%)" "GTP diphosphokinase (61.9%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (38.1%)" "GO:0015969 (26.4%) GO:0042594 (7.4%) GO:0015949 (7%)" "GO:0005886 (25.8%) GO:0009507 (0.6%)" "GO:0008893 (8.7%) GO:0016301 (8.7%) GO:0008728 (8.5%)" "guanosine tetraphosphate metabolic process (26.4%) response to starvation (7.4%) nucleobase-containing small molecule interconversion (7%)" "plasma membrane (25.8%) chloroplast (0.6%)" "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (8.7%) kinase activity (8.7%) GTP diphosphokinase activity (8.5%)" "IPR007685 (9.3%) IPR043519 (9%) IPR004095 (8.9%)" "RelA/SpoT (9.3%) Nucleotidyltransferase superfamily (9%) TGS (8.9%)" AVPVVEAMAAMVLLDNYLLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.3.5 (100%) chorismate synthase (100%) "GO:0008652 (16.7%) GO:0009073 (16.7%) GO:0009423 (16.7%)" GO:0005829 (16.7%) "GO:0004107 (16.7%) GO:0010181 (16.7%)" "amino acid biosynthetic process (16.7%) aromatic amino acid family biosynthetic process (16.7%) chorismate biosynthetic process (16.7%)" cytosol (16.7%) "chorismate synthase activity (16.7%) FMN binding (16.7%)" "IPR000453 (34%) IPR020541 (34%) IPR035904 (32%)" "Chorismate synthase (34%) Chorismate synthase, conserved site (34%) Chorismate synthase AroC superfamily (32%)" GQDVFYGYMLGTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KVGEYEATVHYHK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (19.7%) "GO:0005840 (21.2%) GO:1990904 (19.7%)" "GO:0003735 (19.7%) GO:0019843 (19.7%)" translation (19.7%) "ribosome (21.2%) ribonucleoprotein complex (19.7%)" "structural constituent of ribosome (19.7%) rRNA binding (19.7%)" "IPR020069 (15.1%) IPR036791 (15.1%) IPR000244 (14%)" "Large ribosomal subunit protein bL9, C-terminal (15.1%) Large ribosomal subunit protein bL9, C-terminal domain superfamily (15.1%) Large ribosomal subunit protein bL9 (14%)" EGVAKDEAENLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20%) IPR008932 (20%) IPR013823 (20%)" "Large ribosomal subunit protein bL12 (20%) Large ribosomal subunit protein bL12, oligomerization (20%) Large ribosomal subunit protein bL12, C-terminal (20%)" LLFTSFDK root "2.7.13.3 (33.3%) 3.6.1.- (33.3%) 3.6.1.9 (33.3%)" "histidine kinase (33.3%) In phosphorus-containing anhydrides (33.3%) nucleotide diphosphatase (33.3%)" "GO:0006139 (16.9%) GO:0001508 (1.4%) GO:0006203 (1.4%)" "GO:0005829 (8.5%) GO:0005886 (1.4%) GO:0008076 (1.4%)" "GO:0003676 (16.9%) GO:0008408 (16.9%) GO:0003677 (9.9%)" "nucleobase-containing compound metabolic process (16.9%) action potential (1.4%) dGTP catabolic process (1.4%)" "cytosol (8.5%) plasma membrane (1.4%) voltage-gated potassium channel complex (1.4%)" "nucleic acid binding (16.9%) 3'-5' exonuclease activity (16.9%) DNA binding (9.9%)" "IPR002562 (10.7%) IPR052408 (10.7%) IPR012337 (9.8%)" "3'-5' exonuclease domain (10.7%) Exonuclease MUT-7-like (10.7%) Ribonuclease H-like superfamily (9.8%)" YADVLLMAAELGSPNAQSYFDQVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" LPSYNELFTGDPVWATLEVGGMGQDGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" GYLALDNFDYGSLFNTSFPMNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.3%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.3%)" LFNADGSEAMMCGNASR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.1.1.7 (100%) diaminopimelate epimerase (100%) GO:0009089 (33.3%) GO:0005829 (33.3%) GO:0008837 (33.3%) lysine biosynthetic process via diaminopimelate (33.3%) cytosol (33.3%) diaminopimelate epimerase activity (33.3%) "IPR001653 (50%) IPR018510 (50%)" "Diaminopimelate epimerase, DapF (50%) Diaminopimelate epimerase, active site (50%)" EWEDPAQAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR022385 (18.8%) IPR050708 (18.8%) IPR003284 (12.5%)" "Rhs repeat-associated core (18.8%) Type VI secretion system VgrG/RHS (18.8%) Salmonella virulence plasmid 65kDa B protein (12.5%)" KAHPELPLEYYDER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.-.- (100%) Acting on ester bonds (100%) GO:0000967 (25%) GO:0005829 (25%) "GO:0004518 (25%) GO:0016788 (25%)" rRNA 5'-end processing (25%) cytosol (25%) "nuclease activity (25%) hydrolase activity, acting on ester bonds (25%)" "IPR005227 (25%) IPR006641 (25%) IPR012337 (25%)" "Putative pre-16S rRNA nuclease (25%) YqgF/RNase H-like domain (25%) Ribonuclease H-like superfamily (25%)" SCVDFGFSSVMLDGSALPYEENLALTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (17.3%) GO:0006096 (12%) GO:0030388 (12%)" "GO:0008270 (29.3%) GO:0004332 (16%) GO:0016832 (13.3%)" "carbohydrate metabolic process (17.3%) glycolytic process (12%) fructose 1,6-bisphosphate metabolic process (12%)" "zinc ion binding (29.3%) fructose-bisphosphate aldolase activity (16%) aldehyde-lyase activity (13.3%)" "IPR000771 (29.3%) IPR013785 (29.3%) IPR050246 (29.3%)" "Fructose-bisphosphate aldolase, class-II (29.3%) Aldolase-type TIM barrel (29.3%) Class II Fructose-bisphosphate Aldolase (29.3%)" FTYSYSK root "GO:0007018 (3.1%) GO:0000724 (1.5%) GO:0006260 (1.5%)" "GO:0005737 (6.2%) GO:0016020 (4.6%) GO:0005634 (3.1%)" "GO:0005524 (7.7%) GO:0004672 (4.6%) GO:0008569 (3.1%)" "microtubule-based movement (3.1%) double-strand break repair via homologous recombination (1.5%) DNA replication (1.5%)" "cytoplasm (6.2%) membrane (4.6%) nucleus (3.1%)" "ATP binding (7.7%) protein kinase activity (4.6%) minus-end-directed microtubule motor activity (3.1%)" "IPR041700 (30.1%) IPR008969 (4.4%) IPR011009 (2.9%)" "Outer membrane protein beta-barrel domain 3 (30.1%) Carboxypeptidase-like, regulatory domain superfamily (4.4%) Protein kinase-like domain superfamily (2.9%)" SYTVLLGCLQDNDCHDMTGEGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (33.3%) IPR027417 (33.3%) IPR050678 (33.3%)" "AAA domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) DNA Partitioning ATPase (33.3%)" LDLPNKDEAYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0019698 (32.8%) GO:0042840 (32.8%)" GO:0016746 (34.3%) "D-galacturonate catabolic process (32.8%) D-glucuronate catabolic process (32.8%)" acyltransferase activity (34.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) LYVGFNVK Bacteria Bacteria 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (1.5%) "GO:0005886 (27.3%) GO:0005829 (1.5%)" "GO:0042910 (27.3%) GO:0008324 (26.8%) GO:0015562 (8.1%)" isoleucyl-tRNA aminoacylation (1.5%) "plasma membrane (27.3%) cytosol (1.5%)" "xenobiotic transmembrane transporter activity (27.3%) monoatomic cation transmembrane transporter activity (26.8%) efflux transmembrane transporter activity (8.1%)" "IPR001036 (26%) IPR004763 (25.5%) IPR027463 (25%)" "Acriflavin resistance protein (26%) Cation efflux system CusA-like (25.5%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (25%)" QDAANDALTQPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) QFGFDQLTELLVQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.6%) "GO:0005524 (20.6%) GO:0016881 (20.6%) GO:0008784 (19.6%)" D-alanine biosynthetic process (19.6%) "ATP binding (20.6%) acid-amino acid ligase activity (20.6%) alanine racemase activity (19.6%)" "IPR051046 (10.5%) IPR001608 (10.2%) IPR013221 (10.2%)" "MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.5%) Alanine racemase, N-terminal (10.2%) Mur ligase, central (10.2%)" FKEFSEELCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (88.9%) GO:0016740 (11.1%)" "glycosyltransferase activity (88.9%) transferase activity (11.1%)" "IPR000836 (50%) IPR029057 (50%)" "Phosphoribosyltransferase domain (50%) Phosphoribosyltransferase-like (50%)" LLGPEFLELAFR Pseudomonadati Bacteria Pseudomonadati 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0000272 (35.5%) GO:0045493 (14.5%)" "GO:0004553 (33.9%) GO:0031176 (16.1%)" "polysaccharide catabolic process (35.5%) xylan catabolic process (14.5%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (33.9%) endo-1,4-beta-xylanase activity (16.1%)" "IPR001000 (33.3%) IPR044846 (33.3%) IPR017853 (31.2%)" "Glycoside hydrolase family 10 domain (33.3%) Glycoside hydrolase family 10 (33.3%) Glycoside hydrolase superfamily (31.2%)" EQLSLQVVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" QVGYLTLELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000723 (25.2%) GO:0006281 (25.2%)" GO:0016020 (24.4%) GO:0003678 (25.2%) "telomere maintenance (25.2%) DNA repair (25.2%)" membrane (24.4%) DNA helicase activity (25.2%) "IPR003593 (20.4%) IPR010285 (20.4%) IPR051055 (20.4%)" "AAA+ ATPase domain (20.4%) DNA helicase Pif1-like, DEAD-box helicase domain (20.4%) PIF1 DNA helicase (20.4%)" QLEMYNQEGYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (17%) IPR004602 (17%) IPR041102 (17%)" "ABC transporter-like, ATP-binding domain (17%) UvrABC system subunit A (17%) UvrA, interaction domain (17%)" YYTVQPGNNNLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016829 (80%) GO:0004557 (20%)" "lyase activity (80%) alpha-galactosidase activity (20%)" "IPR052063 (36.2%) IPR011050 (31.9%) IPR012334 (31.9%)" "Polysaccharide Lyase 1 (36.2%) Pectin lyase fold/virulence factor (31.9%) Pectin lyase fold (31.9%)" NEANELNVSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.2%) "GO:0016798 (49.2%) GO:0016787 (1.7%)" carbohydrate metabolic process (49.2%) "hydrolase activity, acting on glycosyl bonds (49.2%) hydrolase activity (1.7%)" "IPR019492 (15.2%) IPR006047 (14.7%) IPR015171 (14.7%)" "Cyclo-malto-dextrinase, C-terminal (15.2%) Glycosyl hydrolase family 13, catalytic domain (14.7%) Cyclomaltodextrinase, N-terminal (14.7%)" KLTALFQPHLYTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.2.8 (100%) UDP-N-acetylmuramate--L-alanine ligase (100%) "GO:0009252 (13.2%) GO:0008360 (13%) GO:0051301 (13%)" "GO:0005737 (12.7%) GO:0016020 (8.1%)" "GO:0005524 (13.5%) GO:0008763 (13%) GO:0016881 (0.6%)" "peptidoglycan biosynthetic process (13.2%) regulation of cell shape (13%) cell division (13%)" "cytoplasm (12.7%) membrane (8.1%)" "ATP binding (13.5%) UDP-N-acetylmuramate-L-alanine ligase activity (13%) acid-amino acid ligase activity (0.6%)" "IPR004101 (14.5%) IPR036615 (14.5%) IPR050061 (14.5%)" "Mur ligase, C-terminal (14.5%) Mur ligase, C-terminal domain superfamily (14.5%) Peptidoglycan biosynthesis MurCDEF (14.5%)" LFPDYLFESSWEVCNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) TVVFVGNDPAVSEMYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (38.9%) GO:0089702 (11.1%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (38.9%) undecaprenyl-phosphate glucose phosphotransferase activity (11.1%)" "IPR003362 (33.3%) IPR017473 (33.3%) IPR017475 (33.3%)" "Bacterial sugar transferase (33.3%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (33.3%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (33.3%)" QLKEDPWEALETK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.5%) IPR012340 (24.5%) IPR035104 (24.5%)" "S1 domain (24.5%) Nucleic acid-binding, OB-fold (24.5%) Ribosomal protein S1-like (24.5%)" LALKADASTPYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) DLLYGVR root "6.3.2.13 (23.9%) 1.3.1.12 (15.2%) 3.1.3.48 (15.2%)" "UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (23.9%) prephenate dehydrogenase (15.2%) protein-tyrosine-phosphatase (15.2%)" "GO:0051301 (3%) GO:0032968 (2.9%) GO:0106004 (2.3%)" "GO:0005886 (5.5%) GO:0005634 (5.3%) GO:0005737 (3.7%)" "GO:0005524 (6%) GO:0016757 (5.1%) GO:0008353 (2.9%)" "cell division (3%) positive regulation of transcription elongation by RNA polymerase II (2.9%) tRNA (guanine-N7)-methylation (2.3%)" "plasma membrane (5.5%) nucleus (5.3%) cytoplasm (3.7%)" "ATP binding (6%) glycosyltransferase activity (5.1%) RNA polymerase II CTD heptapeptide repeat kinase activity (2.9%)" "IPR001173 (3.8%) IPR050256 (3.8%) IPR029044 (3.7%)" "Glycosyltransferase 2-like (3.8%) Glycosyltransferase 2 (3.8%) Nucleotide-diphospho-sugar transferases (3.7%)" VQLNDLNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0042918 (20.7%) GO:0042597 (79.3%) alkanesulfonate transmembrane transport (20.7%) periplasmic space (79.3%) IPR015168 (100%) SsuA/THI5-like (100%) LFQNALDFSDTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50.7%) GO:0050660 (49.3%) plasma membrane (50.7%) flavin adenine dinucleotide binding (49.3%) "IPR000644 (14.5%) IPR002550 (14.5%) IPR005170 (14.5%)" "CBS domain (14.5%) CNNM, transmembrane domain (14.5%) Transporter-associated domain (14.5%)" NGLNLYDGYNFMVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (24.7%) GO:0003700 (24.7%) GO:0005524 (24.7%)" "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (24.7%) ATP binding (24.7%)" "IPR011110 (7.6%) IPR001789 (7.3%) IPR003594 (7.3%)" "Two component regulator propeller (7.6%) Signal transduction response regulator, receiver domain (7.3%) Histidine kinase/HSP90-like ATPase domain (7.3%)" YTLFGGR root "2.1.1.171 (16.7%) 2.6.1.87 (16.7%) 3.1.1.116 (16.7%)" "16S rRNA (guanine(966)-N(2))-methyltransferase (16.7%) UDP-4-amino-4-deoxy-L-arabinose aminotransferase (16.7%) sn-1-specific diacylglycerol lipase (16.7%)" "GO:0006783 (3.7%) GO:0007018 (1.9%) GO:0007052 (1.9%)" "GO:0009289 (3.7%) GO:0005737 (2.8%) GO:0005829 (2.8%)" "GO:0010181 (5.6%) GO:0000976 (3.7%) GO:0003700 (3.7%)" "heme biosynthetic process (3.7%) microtubule-based movement (1.9%) mitotic spindle organization (1.9%)" "pilus (3.7%) cytoplasm (2.8%) cytosol (2.8%)" "FMN binding (5.6%) transcription cis-regulatory region binding (3.7%) DNA-binding transcription factor activity (3.7%)" "IPR026816 (4.4%) IPR029039 (4.4%) IPR008254 (3.8%)" "Flavodoxin domain (4.4%) Flavoprotein-like superfamily (4.4%) Flavodoxin/nitric oxide synthase (3.8%)" YLVNDLLLNLPGLKPVSLGLNK Pseudomonadati Bacteria Pseudomonadati GO:0016020 (2.6%) GO:0016746 (97.4%) membrane (2.6%) acyltransferase activity (97.4%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) MVSFTGDKEMMYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.1.1.- (40%) 2.1.1.173 (40%) 2.1.1.72 (20%)" "Methyltransferases (40%) 23S rRNA (guanine(2445)-N(2))-methyltransferase (40%) site-specific DNA-methyltransferase (adenine-specific) (20%)" "GO:0003723 (33.2%) GO:0070043 (33.2%) GO:0008990 (32.8%)" "RNA binding (33.2%) rRNA (guanine-N7-)-methyltransferase activity (33.2%) rRNA (guanine-N2-)-methyltransferase activity (32.8%)" "IPR000241 (17.4%) IPR004114 (17.4%) IPR054170 (17.4%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.4%) THUMP domain (17.4%) RlmL, ferredoxin-like domain (17.4%)" TLSDLAQTTDGNFYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR002035 (20%) IPR024163 (20%) IPR033881 (20%)" "von Willebrand factor, type A (20%) Aerotolerance regulator, N-terminal (20%) von Willebrand factor domain BatA-type (20%)" VDDFCAEFVTDPLWTYLSGGVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YVLYMYMTSLEDPTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (25.7%) GO:0071555 (25.7%)" "GO:0016758 (25.7%) GO:0016798 (21.7%) GO:0016757 (0.7%)" "carbohydrate metabolic process (25.7%) cell wall organization (25.7%)" "hexosyltransferase activity (25.7%) hydrolase activity, acting on glycosyl bonds (21.7%) glycosyltransferase activity (0.7%)" "IPR007184 (33.6%) IPR028583 (33.6%) IPR023296 (32.8%)" "Mannoside phosphorylase (33.6%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (33.6%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.8%)" LGAEKFPLCLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (32.3%) GO:0006730 (1.1%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (32.3%) one-carbon metabolic process (1.1%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.4%) IPR020628 (33.3%) IPR027417 (32.2%)" "Formate-tetrahydrofolate ligase, FTHFS (34.4%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33.3%) P-loop containing nucleoside triphosphate hydrolase (32.2%)" YLLTATVR root "GO:0044718 (6.8%) GO:0006826 (3.7%) GO:0033214 (0.7%)" "GO:0009279 (79.3%) GO:0005886 (0.3%) GO:0016020 (0.3%)" "GO:0015344 (7.8%) GO:0004222 (0.1%) GO:0030674 (0.1%)" "siderophore transmembrane transport (6.8%) iron ion transport (3.7%) siderophore-iron import into cell (0.7%)" "cell outer membrane (79.3%) plasma membrane (0.3%) membrane (0.3%)" "siderophore uptake transmembrane transporter activity (7.8%) metalloendopeptidase activity (0.1%) protein-macromolecule adaptor activity (0.1%)" "IPR023996 (12.8%) IPR039426 (12.8%) IPR012910 (12.8%)" "TonB-dependent outer membrane protein, SusC/RagA (12.8%) TonB-dependent receptor-like (12.8%) TonB-dependent receptor, plug domain (12.8%)" LNLHLAEDNATLSLDSSGESLHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.9%) IPR002052 (16.9%) IPR004114 (16.9%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.9%) DNA methylase, N-6 adenine-specific, conserved site (16.9%) THUMP domain (16.9%)" LMSQALR root "4.2.1.46 (18.8%) 3.6.1.8 (12.5%) 4.1.1.35 (12.5%)" "dTDP-glucose 4,6-dehydratase (18.8%) ATP diphosphatase (12.5%) UDP-glucuronate decarboxylase (12.5%)" "GO:0006310 (14.3%) GO:0006281 (14.3%) GO:0009432 (8.1%)" "GO:0005829 (13.6%) GO:0005737 (0.1%) GO:0005634 (0%)" "GO:0005524 (14.3%) GO:0003697 (14.3%) GO:0140664 (14.2%)" "DNA recombination (14.3%) DNA repair (14.3%) SOS response (8.1%)" "cytosol (13.6%) cytoplasm (0.1%) nucleus (0%)" "ATP binding (14.3%) single-stranded DNA binding (14.3%) ATP-dependent DNA damage sensor activity (14.2%)" "IPR013765 (14.4%) IPR049428 (14.4%) IPR027417 (14.4%)" "DNA recombination and repair protein RecA (14.4%) RecA-like, N-terminal (14.4%) P-loop containing nucleoside triphosphate hydrolase (14.4%)" ELGKPTGNDMVEGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.90 (100%) all-trans-octaprenyl-diphosphate synthase (100%) GO:0008299 (50%) "GO:0004659 (43.8%) GO:0106350 (6.3%)" isoprenoid biosynthetic process (50%) "prenyltransferase activity (43.8%) all-trans-octaprenyl-diphosphate synthase activity (6.3%)" "IPR000092 (33.3%) IPR008949 (33.3%) IPR033749 (33.3%)" "Polyprenyl synthetase-like (33.3%) Isoprenoid synthase domain superfamily (33.3%) Polyprenyl synthetase, conserved site (33.3%)" GAVHSADLEYAMGTLPTNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.3%) IPR050309 (20.3%) IPR019819 (19.8%)" "Carboxylesterase, type B (20.3%) Type-B Carboxylesterase/Lipase (20.3%) Carboxylesterase type B, conserved site (19.8%)" AETFSMDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.6%) IPR013148 (14.6%) IPR013189 (14.6%)" "Glycoside hydrolase, family 32 (14.6%) Glycosyl hydrolase family 32, N-terminal (14.6%) Glycosyl hydrolase family 32, C-terminal (14.6%)" GEAYLSFK root "1.-.-.- (50%) 3.1.-.- (50%)" "Oxidoreductases (50%) Acting on ester bonds (50%)" "GO:0006887 (12.5%) GO:0043571 (8.3%) GO:0051607 (8.3%)" "GO:0005770 (12.5%) GO:0099503 (12.5%) GO:0005829 (4.2%)" "GO:0003677 (8.3%) GO:0004520 (8.3%) GO:0016787 (8.3%)" "exocytosis (12.5%) maintenance of CRISPR repeat elements (8.3%) defense response to virus (8.3%)" "late endosome (12.5%) secretory vesicle (12.5%) cytosol (4.2%)" "DNA binding (8.3%) DNA endonuclease activity (8.3%) hydrolase activity (8.3%)" "IPR024480 (32.8%) IPR036737 (32.8%) IPR000008 (4.5%)" "Domain of unknown function DUF3868 (32.8%) OmpA-like domain superfamily (32.8%) C2 domain (4.5%)" SALELWK root "2.7.10.2 (9.5%) 2.7.13.3 (9.5%) 3.1.2.4 (9.5%)" "non-specific protein-tyrosine kinase (9.5%) histidine kinase (9.5%) 3-hydroxyisobutyryl-CoA hydrolase (9.5%)" "GO:0006412 (15.8%) GO:0015833 (0.8%) GO:0006351 (0.3%)" "GO:0015935 (15.6%) GO:0005737 (0.9%) GO:0016020 (0.9%)" "GO:0003735 (15.7%) GO:0019843 (15.7%) GO:0000049 (13.3%)" "translation (15.8%) peptide transport (0.8%) DNA-templated transcription (0.3%)" "small ribosomal subunit (15.6%) cytoplasm (0.9%) membrane (0.9%)" "structural constituent of ribosome (15.7%) rRNA binding (15.7%) tRNA binding (13.3%)" "IPR000235 (14.9%) IPR023798 (14.9%) IPR036823 (14.9%)" "Small ribosomal subunit protein uS7 (14.9%) Small ribosomal subunit protein uS7 domain (14.9%) Small ribosomal subunit protein uS7 domain superfamily (14.9%)" VAFLDNK root "5.6.2.2 (25%) 2.3.1.191 (12.5%) 2.7.4.16 (12.5%)" "DNA topoisomerase (ATP-hydrolyzing) (25%) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (12.5%) thiamine-phosphate kinase (12.5%)" "GO:0006508 (3%) GO:0046677 (3%) GO:0007165 (2.2%)" "GO:0016020 (9.6%) GO:0005886 (3%) GO:0030313 (3%)" "GO:0005524 (4.4%) GO:0003677 (3%) GO:0016874 (3%)" "proteolysis (3%) response to antibiotic (3%) signal transduction (2.2%)" "membrane (9.6%) plasma membrane (3%) cell envelope (3%)" "ATP binding (4.4%) DNA binding (3%) ligase activity (3%)" "IPR001478 (2.4%) IPR027417 (2.4%) IPR036034 (2.4%)" "PDZ domain (2.4%) P-loop containing nucleoside triphosphate hydrolase (2.4%) PDZ superfamily (2.4%)" VNALPLLGELLKEELNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003677 (100%) DNA binding (100%) "IPR010982 (66.7%) IPR001387 (33.3%)" "Lambda repressor-like, DNA-binding domain superfamily (66.7%) Cro/C1-type, helix-turn-helix domain (33.3%)" KDFSWSANVNFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" TLGPLEERPGHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" LLVPHSYGTTSASGSVQACVYDMTLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR032252 (51.4%) IPR046357 (48.6%)" "Protein of unknown function DUF4827 (51.4%) Peptidyl-prolyl cis-trans isomerase domain superfamily (48.6%)" MTNLAQLVNVLQSMLLTDTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (27.2%) IPR013780 (25%) IPR017853 (25%)" "Alpha-L-arabinofuranosidase, C-terminal (27.2%) Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%)" AYAGTSYLVNATSLAGMPYVSTSDAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" SLSELDDLLESLNLSFGTDLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011260 (16.7%) IPR011262 (16.7%) IPR011263 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (16.7%) DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%)" SLVELANAFAEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0051539 (33.7%) GO:0003824 (32.6%) GO:0005506 (32.6%)" "4 iron, 4 sulfur cluster binding (33.7%) catalytic activity (32.6%) iron ion binding (32.6%)" "IPR013704 (14.8%) IPR022946 (14.8%) IPR006638 (14.3%)" "UPF0313, N-terminal (14.8%) Uncharacterised protein family UPF0313 (14.8%) Elp3/MiaA/NifB-like, radical SAM core domain (14.3%)" TVLEYSPSQGYLSYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.6.1.- (66.7%) 2.6.1.1 (33.3%)" "Transaminases (66.7%) aspartate transaminase (33.3%)" GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (30.6%) GO:0004069 (2.8%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (30.6%) L-aspartate:2-oxoglutarate aminotransferase activity (2.8%)" "IPR004839 (21.1%) IPR050596 (21.1%) IPR015421 (19.3%)" "Aminotransferase, class I/classII, large domain (21.1%) Aspartate/prephenate aminotransferase-like (21.1%) Pyridoxal phosphate-dependent transferase, major domain (19.3%)" LYQNDPSAVDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR005151 (50%) IPR029045 (50%)" "Tail specific protease (50%) ClpP/crotonase-like domain superfamily (50%)" EANLGGGGFLGAYPTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.5%) IPR023996 (15.5%) IPR023997 (15.5%)" "TonB-dependent receptor, plug domain (15.5%) TonB-dependent outer membrane protein, SusC/RagA (15.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.5%)" HLFGELLAELQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0016787 (50%) GO:0046872 (50%)" "hydrolase activity (50%) metal ion binding (50%)" IPR039461 (100%) Peptidase family M49 (100%) LYGVQQAEDVKNLYDLPNLLLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.3%) IPR041542 (20.3%) IPR051795 (20.3%)" "Glycoside hydrolase, family 43 (20.3%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.3%) Glycosyl Hydrolase Family 43 (20.3%)" KQATELLAEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.7%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.7%)" "IPR000185 (7.9%) IPR011115 (7.9%) IPR014001 (7.9%)" "Protein translocase subunit SecA (7.9%) SecA DEAD-like, N-terminal (7.9%) Helicase superfamily 1/2, ATP-binding domain (7.9%)" LSWDLDK root "2.1.1.163 (92.1%) 2.1.1.201 (2.6%) 2.3.1.15 (1.3%)" "demethylmenaquinone methyltransferase (92.1%) 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase (2.6%) glycerol-3-phosphate 1-O-acyltransferase (1.3%)" "GO:0009234 (21.9%) GO:0032259 (21.9%) GO:0006353 (2.3%)" "GO:0016020 (1.9%) GO:0000145 (1.6%) GO:0005829 (1.3%)" "GO:0043770 (21.9%) GO:0003676 (2.3%) GO:0000149 (1.6%)" "menaquinone biosynthetic process (21.9%) methylation (21.9%) DNA-templated transcription termination (2.3%)" "membrane (1.9%) exocyst (1.6%) cytosol (1.3%)" "demethylmenaquinone methyltransferase activity (21.9%) nucleic acid binding (2.3%) SNARE binding (1.6%)" "IPR004033 (21.1%) IPR023576 (21.1%) IPR029063 (21.1%)" "UbiE/COQ5 methyltransferase (21.1%) UbiE/COQ5 methyltransferase, conserved site (21.1%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (21.1%)" ASHNQLLLSQLMADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR025857 (34%) IPR051447 (34%) IPR003838 (32%)" "MacB-like periplasmic core domain (34%) Lipoprotein-releasing system transmembrane protein (34%) ABC3 transporter permease, C-terminal (32%)" NKTNFGSVANTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" WELLNATK root 2.5.1.- (100%) Transferring alkyl or aryl groups, other than methyl groups (100%) "GO:0016094 (29.5%) GO:0016226 (1.6%)" "GO:0005737 (1.6%) GO:0016020 (1.6%)" "GO:0045547 (29.5%) GO:0000287 (27.9%) GO:0005524 (1.6%)" "polyprenol biosynthetic process (29.5%) iron-sulfur cluster assembly (1.6%)" "cytoplasm (1.6%) membrane (1.6%)" "ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity (29.5%) magnesium ion binding (27.9%) ATP binding (1.6%)" "IPR001441 (29.5%) IPR018520 (29.5%) IPR036424 (27.9%)" "Decaprenyl diphosphate synthase-like (29.5%) Di-trans-poly-cis-decaprenylcistransferase-like, conserved site (29.5%) Decaprenyl diphosphate synthase-like superfamily (27.9%)" DTKNGAVSDLDGNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR037066 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent receptor, plug domain superfamily (13%)" YGLPGDFR Bacteria Bacteria "2.1.1.- (83.3%) 2.1.1.191 (16.7%)" "Methyltransferases (83.3%) 23S rRNA (cytosine(1962)-C(5))-methyltransferase (16.7%)" GO:0032259 (11.1%) GO:0005886 (22.2%) "GO:0015079 (22.2%) GO:0015293 (22.2%) GO:0003723 (11.1%)" methylation (11.1%) plasma membrane (22.2%) "potassium ion transmembrane transporter activity (22.2%) symporter activity (22.2%) RNA binding (11.1%)" "IPR053952 (15.7%) IPR003855 (15.2%) IPR023051 (15.2%)" "K+ potassium transporter, C-terminal domain (15.7%) Potassium transporter (15.2%) Low affinity potassium transport system protein Kup (15.2%)" LVQDALEK root "3.6.3.- (32.1%) 7.6.2.2 (32.1%) 3.6.3.44 (17.9%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (32.1%) ABC-type xenobiotic transporter (32.1%) Transferred entry: 7.6.2.2 (17.9%)" "GO:0090374 (7%) GO:0055085 (0.5%) GO:0006813 (0.3%)" "GO:0005886 (13.6%) GO:0005743 (6.2%) GO:0016020 (2.7%)" "GO:0005524 (20.4%) GO:0016887 (20.3%) GO:0015421 (15.9%)" "oligopeptide export from mitochondrion (7%) transmembrane transport (0.5%) potassium ion transport (0.3%)" "plasma membrane (13.6%) mitochondrial inner membrane (6.2%) membrane (2.7%)" "ATP binding (20.4%) ATP hydrolysis activity (20.3%) ABC-type oligopeptide transporter activity (15.9%)" "IPR003439 (13.4%) IPR027417 (13.4%) IPR017871 (13.2%)" "ABC transporter-like, ATP-binding domain (13.4%) P-loop containing nucleoside triphosphate hydrolase (13.4%) ABC transporter-like, conserved site (13.2%)" GYSPESLR root "6.1.1.18 (99.5%) 6.1.1.16 (0.5%)" "glutamine--tRNA ligase (99.5%) cysteine--tRNA ligase (0.5%)" "GO:0006425 (24.3%) GO:0006424 (0.8%) GO:0006423 (0.1%)" "GO:0005829 (24.5%) GO:0016020 (0.5%) GO:0005737 (0.1%)" "GO:0005524 (24.5%) GO:0004819 (24.3%) GO:0008270 (0.2%)" "glutaminyl-tRNA aminoacylation (24.3%) glutamyl-tRNA aminoacylation (0.8%) cysteinyl-tRNA aminoacylation (0.1%)" "cytosol (24.5%) membrane (0.5%) cytoplasm (0.1%)" "ATP binding (24.5%) glutamine-tRNA ligase activity (24.3%) zinc ion binding (0.2%)" "IPR020058 (10.3%) IPR050132 (10.3%) IPR004514 (10.2%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.3%) Glutamine/Glutamate--tRNA Ligase (10.3%) Glutamine-tRNA synthetase (10.2%)" VRPEAVLVDGNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.26.4 (100%) ribonuclease H (100%) "GO:0006298 (14.3%) GO:0043137 (14.3%)" "GO:0005737 (14.3%) GO:0032299 (14.3%)" "GO:0003723 (14.3%) GO:0004523 (14.3%) GO:0030145 (14.3%)" "mismatch repair (14.3%) DNA replication, removal of RNA primer (14.3%)" "cytoplasm (14.3%) ribonuclease H2 complex (14.3%)" "RNA binding (14.3%) RNA-DNA hybrid ribonuclease activity (14.3%) manganese ion binding (14.3%)" "IPR001352 (20.2%) IPR022898 (20.2%) IPR024567 (20.2%)" "Ribonuclease HII/HIII (20.2%) Ribonuclease HII (20.2%) Ribonuclease HII/HIII domain (20.2%)" STQQLQAMLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR003790 (25.3%) IPR017853 (25.3%) IPR052177 (25.3%)" "Glycosyl hydrolase-like 10 (25.3%) Glycoside hydrolase superfamily (25.3%) Divisome-localized Glycosyl Hydrolase (25.3%)" YLLLMGR root "2.1.1.- (16.7%) 2.7.13.3 (16.7%) 1.4.1.24 (11.1%)" "Methyltransferases (16.7%) histidine kinase (16.7%) 3-dehydroquinate synthase II (11.1%)" "GO:0006351 (2.7%) GO:0006418 (1.7%) GO:0006508 (1.1%)" "GO:0043190 (15.2%) GO:0016020 (9.5%) GO:0005886 (4.2%)" "GO:0005548 (15.2%) GO:0022857 (4%) GO:0003677 (3.8%)" "DNA-templated transcription (2.7%) tRNA aminoacylation for protein translation (1.7%) proteolysis (1.1%)" "ATP-binding cassette (ABC) transporter complex (15.2%) membrane (9.5%) plasma membrane (4.2%)" "phospholipid transporter activity (15.2%) transmembrane transporter activity (4%) DNA binding (3.8%)" "IPR030802 (15.6%) IPR036259 (4.2%) IPR050815 (2.9%)" "ABC transporter permease MalE (15.6%) MFS transporter superfamily (4.2%) Transcription factor, fungi (2.9%)" KLPVTTLLR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (19.8%) GO:0006508 (0.3%) GO:0006260 (0%)" "GO:0000428 (19.7%) GO:0016020 (0.1%) GO:0005730 (0%)" "GO:0003677 (19.9%) GO:0003899 (19.8%) GO:0032549 (19.7%)" "DNA-templated transcription (19.8%) proteolysis (0.3%) DNA replication (0%)" "DNA-directed RNA polymerase complex (19.7%) membrane (0.1%) nucleolus (0%)" "DNA binding (19.9%) DNA-directed RNA polymerase activity (19.8%) ribonucleoside binding (19.7%)" "IPR007642 (8%) IPR015712 (8%) IPR007645 (7.9%)" "RNA polymerase Rpb2, domain 2 (8%) DNA-directed RNA polymerase, subunit 2 (8%) RNA polymerase Rpb2, domain 3 (7.9%)" LNATVSPDGK root "GO:0006950 (3.1%) GO:0036180 (3.1%) GO:1900445 (3.1%)" GO:0016020 (87.5%) GO:0000156 (3.1%) "response to stress (3.1%) filamentous growth of a population of unicellular organisms in response to biotic stimulus (3.1%) positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus (3.1%)" membrane (87.5%) phosphorelay response regulator activity (3.1%) "IPR025874 (81.8%) IPR011990 (9.1%) IPR001789 (3%)" "Double zinc ribbon (81.8%) Tetratricopeptide-like helical domain superfamily (9.1%) Signal transduction response regulator, receiver domain (3%)" ATGSQLLNVFDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" REYDHELNDEELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (8.1%) IPR012162 (8.1%) IPR015847 (8.1%)" "Exoribonuclease, phosphorolytic domain 1 (8.1%) Polyribonucleotide nucleotidyltransferase (8.1%) Exoribonuclease, phosphorolytic domain 2 (8.1%)" LLFTDKDDLYALPVSVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" EPEKFDQVVEELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006355 (34.3%) GO:0043200 (11.4%)" GO:0005829 (11.4%) GO:0043565 (42.9%) "regulation of DNA-templated transcription (34.3%) response to amino acid (11.4%)" cytosol (11.4%) sequence-specific DNA binding (42.9%) "IPR019887 (14%) IPR019888 (14%) IPR000485 (13.1%)" "Transcription regulator AsnC/Lrp, ligand binding domain (14%) Transcription regulator AsnC-like (14%) AsnC-type HTH domain (13.1%)" DNNPQMVDGEWNYVNNPTYQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" FTVDGLANELYQLLPGEPGRDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.182 (100%) lipid-A-disaccharide synthase (100%) GO:0009245 (25%) GO:0016020 (25%) "GO:0005543 (25%) GO:0008915 (25%)" lipid A biosynthetic process (25%) membrane (25%) "phospholipid binding (25%) lipid-A-disaccharide synthase activity (25%)" IPR003835 (100%) Glycosyl transferase, family 19 (100%) GNTYYYATYVQLQGLVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FDSGKNEFTDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GESTWYVENEDGSLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MPVPVLWVWQEDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016740 (100%) transferase activity (100%) "IPR001173 (33.3%) IPR029044 (33.3%) IPR050834 (33.3%)" "Glycosyltransferase 2-like (33.3%) Nucleotide-diphospho-sugar transferases (33.3%) Glycosyltransferase 2 family enzymes (33.3%)" RFNQTYAPVLVEPELLLPELACCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" EDLQHAFLNHQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (42.4%) GO:0005886 (44.1%) "GO:0016787 (11.9%) GO:0016301 (1.7%)" guanosine tetraphosphate metabolic process (42.4%) plasma membrane (44.1%) "hydrolase activity (11.9%) kinase activity (1.7%)" "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" GLELTAAYR root "GO:0044718 (32.3%) GO:1902657 (1%)" GO:0009279 (34.4%) GO:0015344 (32.3%) "siderophore transmembrane transport (32.3%) protein localization to prospore membrane (1%)" cell outer membrane (34.4%) siderophore uptake transmembrane transporter activity (32.3%) "IPR039426 (23.1%) IPR036942 (22.4%) IPR037066 (22.4%)" "TonB-dependent receptor-like (23.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (22.4%) TonB-dependent receptor, plug domain superfamily (22.4%)" TDFVPLCFGVDEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella TNFFSMVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LGSCVLNTPEGER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016491 (50.7%) GO:0051536 (49.3%)" "oxidoreductase activity (50.7%) iron-sulfur cluster binding (49.3%)" "IPR023753 (25.4%) IPR028261 (25.4%) IPR009051 (24.6%)" "FAD/NAD(P)-binding domain (25.4%) Dihydroprymidine dehydrogenase domain II (25.4%) Alpha-helical ferredoxin (24.6%)" FFLAYAGVWGQNLTDKELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.7%) IPR008753 (20.7%) IPR018497 (20.7%)" "Peptidase M13 (20.7%) Peptidase M13, N-terminal domain (20.7%) Peptidase M13, C-terminal domain (20.7%)" KPFALVGHGVELGGAHNELLEFLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (13.1%) IPR012000 (13.1%) IPR045229 (13.1%)" "Thiamine pyrophosphate enzyme, TPP-binding (13.1%) Thiamine pyrophosphate enzyme, central domain (13.1%) Thiamine pyrophosphate enzyme (13.1%)" LEVMPLSTEDYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009228 (24.6%) "GO:0051539 (26.2%) GO:0003824 (24.6%) GO:0005506 (24.6%)" thiamine biosynthetic process (24.6%) "4 iron, 4 sulfur cluster binding (26.2%) catalytic activity (24.6%) iron ion binding (24.6%)" "IPR010722 (20.8%) IPR034428 (20.8%) IPR007197 (19.5%)" "Biotin and thiamin synthesis-associated domain (20.8%) ThiH/NocL/HydG-like (20.8%) Radical SAM (19.5%)" CYLTLAWGDGYEATDGVDHLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" MLLEWLDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (25%) GO:0031564 (24.1%) GO:0006355 (0.9%)" GO:0005829 (25%) GO:0003723 (25%) "DNA-templated transcription termination (25%) transcription antitermination (24.1%) regulation of DNA-templated transcription (0.9%)" cytosol (25%) RNA binding (25%) "IPR006027 (33.7%) IPR011605 (33.7%) IPR035926 (32.5%)" "NusB/RsmB/TIM44 (33.7%) NusB antitermination factor (33.7%) NusB-like superfamily (32.5%)" GHNLDYSSLTSFCGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.13 (100%) phospho-N-acetylmuramoyl-pentapeptide-transferase (100%) "GO:0071555 (15.1%) GO:0008360 (12.8%) GO:0009252 (12.8%)" GO:0005886 (15.1%) "GO:0008963 (12.8%) GO:0046872 (12.8%) GO:0016780 (2.3%)" "cell wall organization (15.1%) regulation of cell shape (12.8%) peptidoglycan biosynthetic process (12.8%)" plasma membrane (15.1%) "phospho-N-acetylmuramoyl-pentapeptide-transferase activity (12.8%) metal ion binding (12.8%) phosphotransferase activity, for other substituted phosphate groups (2.3%)" "IPR000715 (35.1%) IPR018480 (35.1%) IPR003524 (29.7%)" "Glycosyl transferase, family 4 (35.1%) Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site (35.1%) Phospho-N-acetylmuramoyl-pentapeptide transferase (29.7%)" QGTRPNLSVSNPDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.8%) IPR002052 (16.8%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) DNA methylase, N-6 adenine-specific, conserved site (16.8%) THUMP domain (16.8%)" KQVLDLCTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.8%) IPR032790 (20.8%) IPR008928 (19.5%)" "Glycogen debranching enzyme (20.8%) Glycogen debranching enzyme, C-terminal (20.8%) Six-hairpin glycosidase superfamily (19.5%)" LYVNFDTNKAEVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (60%) IPR025970 (40%)" "Outer membrane protein SusF/SusE-like, C-terminal (60%) SusE outer membrane protein (40%)" KGLNVFLLGLGNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR002035 (25.3%) IPR024163 (25.3%) IPR050768 (25.3%)" "von Willebrand factor, type A (25.3%) Aerotolerance regulator, N-terminal (25.3%) UPF0353/GerABKA protein families (25.3%)" LGVDLTCEPVLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR048441 (50%) IPR048496 (50%)" "DUF1846, C-terminal (50%) DUF1846, N-terminal domain (50%)" TLCSGLAAYYEPEQLLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" WKAPLNEAVHGVELSTEAGLPQFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR011990 (33.3%) IPR033985 (30.3%)" "RagB/SusD domain (36.4%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (30.3%)" TEFLACEHYPQLKPFLPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (22.9%) GO:0006529 (2.1%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (22.9%) GO:0000166 (2.1%)" "L-asparagine biosynthetic process (22.9%) obsolete asparagine biosynthetic process (2.1%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (22.9%) nucleotide binding (2.1%)" "IPR004618 (34.3%) IPR006195 (34.3%) IPR045864 (31.4%)" "Aspartate--ammonia ligase (34.3%) Aminoacyl-tRNA synthetase, class II (34.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (31.4%)" LADDEALYGLGQLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (33.7%) "GO:0004553 (33.7%) GO:0030246 (32.7%)" carbohydrate metabolic process (33.7%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.7%) carbohydrate binding (32.7%)" "IPR000322 (12.6%) IPR025887 (12.6%) IPR033403 (12.6%)" "Glycoside hydrolase family 31, TIM barrel domain (12.6%) Glycoside hydrolase family 31, N-terminal domain (12.6%) Domain of unknown function DUF5110 (12.6%)" TTCELALGDNLLSLPWVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0019698 (33.5%) GO:0042840 (33.5%)" GO:0016746 (32.9%) "D-galacturonate catabolic process (33.5%) D-glucuronate catabolic process (33.5%)" acyltransferase activity (32.9%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) LLLLDDDPLQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0005886 (31.2%) "GO:0000155 (31.2%) GO:0009927 (31.2%) GO:0005524 (6.4%)" plasma membrane (31.2%) "phosphorelay sensor kinase activity (31.2%) histidine phosphotransfer kinase activity (31.2%) ATP binding (6.4%)" "IPR001789 (11.4%) IPR003594 (11.4%) IPR005467 (11.4%)" "Signal transduction response regulator, receiver domain (11.4%) Histidine kinase/HSP90-like ATPase domain (11.4%) Histidine kinase domain (11.4%)" RGELNLFEESDEVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DETNEVVLDGLNSMYSSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (44.4%) IPR011990 (40.7%) IPR050498 (14.8%)" "Tetratricopeptide repeat (44.4%) Tetratricopeptide-like helical domain superfamily (40.7%) Photosystem I assembly protein Ycf3 (14.8%)" QVEVTLNGLGER root "2.3.3.13 (91.9%) 2.3.3.17 (8.1%)" "2-isopropylmalate synthase (91.9%) methylthioalkylmalate synthase (8.1%)" "GO:0009098 (23.3%) GO:0019761 (2.4%) GO:0019752 (1%)" "GO:0009507 (10.2%) GO:0005737 (8.3%) GO:0009536 (0.4%)" "GO:0003852 (23.7%) GO:0046872 (8.6%) GO:0003985 (7.7%)" "L-leucine biosynthetic process (23.3%) glucosinolate biosynthetic process (2.4%) carboxylic acid metabolic process (1%)" "chloroplast (10.2%) cytoplasm (8.3%) plastid (0.4%)" "2-isopropylmalate synthase activity (23.7%) metal ion binding (8.6%) acetyl-CoA C-acetyltransferase activity (7.7%)" "IPR000891 (14.3%) IPR050073 (14.3%) IPR013785 (14%)" "Pyruvate carboxyltransferase (14.3%) 2-IPM synthase/homocitrate synthase-like (14.3%) Aldolase-type TIM barrel (14%)" LGAGTDAYYMPDNLGNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.8%) IPR012910 (20.8%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.8%) TonB-dependent receptor, plug domain (20.8%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" GGHSGLELNEGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) "GO:0006508 (25%) GO:0043171 (0.1%)" GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" "proteolysis (25%) peptide catabolic process (0.1%)" cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (31.1%) IPR002933 (31.1%) IPR011650 (31.1%)" "Peptidase M20C, Xaa-His dipeptidase (31.1%) Peptidase M20 (31.1%) Peptidase M20, dimerisation domain (31.1%)" VYAPESYGDLFKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.26.11 (100%) ribonuclease Z (100%) "GO:0008270 (50%) GO:0042781 (50%)" "zinc ion binding (50%) 3'-tRNA processing endoribonuclease activity (50%)" "IPR001279 (33.8%) IPR013471 (33.8%) IPR036866 (32.5%)" "Metallo-beta-lactamase (33.8%) Ribonuclease Z/BN (33.8%) Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (32.5%)" LQAQDPELLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.11.6 (100%) exodeoxyribonuclease VII (100%) GO:0006308 (20.2%) "GO:0009318 (20.2%) GO:0005737 (19.7%)" "GO:0008855 (20.2%) GO:0003676 (19.7%)" DNA catabolic process (20.2%) "exodeoxyribonuclease VII complex (20.2%) cytoplasm (19.7%)" "exodeoxyribonuclease VII activity (20.2%) nucleic acid binding (19.7%)" "IPR003753 (33.6%) IPR020579 (33.6%) IPR025824 (32.8%)" "Exonuclease VII, large subunit (33.6%) Exonuclease VII, large subunit, C-terminal (33.6%) OB-fold nucleic acid binding domain (32.8%)" FNVTAMTR root 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0006265 (16.6%) "GO:0005737 (16.6%) GO:0009330 (16.6%)" "GO:0003677 (16.6%) GO:0003918 (16.6%) GO:0005524 (16.6%)" DNA topological change (16.6%) "cytoplasm (16.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.6%)" "DNA binding (16.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.6%) ATP binding (16.6%)" "IPR002205 (20.4%) IPR050220 (20.4%) IPR013757 (19.6%)" "DNA topoisomerase, type IIA, domain A (20.4%) Type II DNA Topoisomerases (20.4%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.6%)" ENFHDVVLSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.8%) GO:0019288 (18.8%)" "GO:0046429 (18.8%) GO:0051539 (18.8%) GO:0005506 (17.8%)" "terpenoid biosynthetic process (18.8%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.8%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.8%) 4 iron, 4 sulfur cluster binding (18.8%) iron ion binding (17.8%)" "IPR004588 (26%) IPR011005 (24.7%) IPR017178 (24.7%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26%) Dihydropteroate synthase-like superfamily (24.7%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.7%)" ENGETFNPGAMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (31.4%) GO:0005576 (31.4%) "GO:0004650 (31.4%) GO:0004557 (5.7%)" carbohydrate metabolic process (31.4%) extracellular region (31.4%) "polygalacturonase activity (31.4%) alpha-galactosidase activity (5.7%)" "IPR000743 (31.4%) IPR011050 (31.4%) IPR012334 (31.4%)" "Glycoside hydrolase, family 28 (31.4%) Pectin lyase fold/virulence factor (31.4%) Pectin lyase fold (31.4%)" TAEALLDEFFATTFEGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.6 (100%) ribose-5-phosphate isomerase (100%) "GO:0009052 (30.8%) GO:0019316 (30.8%) GO:0005975 (3.8%)" "GO:0004751 (30.8%) GO:0016861 (3.8%)" "pentose-phosphate shunt, non-oxidative branch (30.8%) D-allose catabolic process (30.8%) carbohydrate metabolic process (3.8%)" "ribose-5-phosphate isomerase activity (30.8%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (3.8%)" "IPR003500 (40.9%) IPR036569 (40.9%) IPR004785 (18.2%)" "Sugar-phosphate isomerase, RpiB/LacA/LacB family (40.9%) Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily (40.9%) Ribose 5-phosphate isomerase B (18.2%)" MEGTPTLAEWLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (24.1%) GO:0005737 (24.1%) "GO:0046872 (25.9%) GO:0070006 (24.1%) GO:0016787 (1.7%)" proteolysis (24.1%) cytoplasm (24.1%) "metal ion binding (25.9%) metalloaminopeptidase activity (24.1%) hydrolase activity (1.7%)" "IPR000587 (13.2%) IPR050422 (13.2%) IPR029149 (12.7%)" "Creatinase, N-terminal (13.2%) Xaa-Pro aminopeptidase P (13.2%) Creatinase/Aminopeptidase P/Spt16, N-terminal (12.7%)" TTDERPFLFLSGMGVTLPAFEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0042026 (33.3%) GO:0005737 (33.3%) GO:0003755 (33.3%) protein refolding (33.3%) cytoplasm (33.3%) peptidyl-prolyl cis-trans isomerase activity (33.3%) "IPR001179 (33.3%) IPR046357 (33.3%) IPR048261 (33.3%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (33.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (33.3%) PPIase chaperone SlpA/SlyD-like, insertion domain superfamily (33.3%)" LTEVDGDALLTYADGTLCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20%) "GO:0000155 (20%) GO:0003700 (20%) GO:0005524 (20%)" membrane (20%) "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR001789 (6.6%) IPR003594 (6.6%) IPR003661 (6.6%)" "Signal transduction response regulator, receiver domain (6.6%) Histidine kinase/HSP90-like ATPase domain (6.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.6%)" AADAGGAEMNEGTAEEYAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" LMGLADDR root "GO:0006352 (5.3%) GO:0006897 (5.3%) GO:0009103 (5.3%)" "GO:0005768 (5.3%) GO:0005829 (5.3%) GO:0005886 (5.3%)" "GO:0003700 (5.3%) GO:0005085 (5.3%) GO:0005096 (5.3%)" "DNA-templated transcription initiation (5.3%) endocytosis (5.3%) lipopolysaccharide biosynthetic process (5.3%)" "endosome (5.3%) cytosol (5.3%) plasma membrane (5.3%)" "DNA-binding transcription factor activity (5.3%) guanyl-nucleotide exchange factor activity (5.3%) GTPase activator activity (5.3%)" "IPR000715 (6.3%) IPR001936 (6.3%) IPR003123 (6.3%)" "Glycosyl transferase, family 4 (6.3%) Ras GTPase-activating domain (6.3%) VPS9 domain (6.3%)" FPSELFTAGSPLTTLDLSGNQMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005615 (72.7%) GO:0005737 (9.1%) GO:0005886 (9.1%)" "extracellular space (72.7%) cytoplasm (9.1%) plasma membrane (9.1%)" "IPR001611 (16.9%) IPR032675 (16.1%) IPR027899 (15.3%)" "Leucine-rich repeat (16.9%) Leucine-rich repeat domain superfamily (16.1%) Domain of unknown function DUF4458 (15.3%)" GLAPAVLTPLALFVTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015920 (50%) GO:0043190 (50%) lipopolysaccharide transport (50%) ATP-binding cassette (ABC) transporter complex (50%) IPR005495 (100%) Permease LptG/LptF-related (100%) LMLDAPYQKPDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (51.9%) 6.3.4.16 (48.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (51.9%) carbamoyl-phosphate synthase (ammonia) (48.1%)" "GO:0006221 (13.9%) GO:0006526 (13.9%) GO:0006541 (13.9%)" GO:0005737 (13.9%) "GO:0004088 (13.9%) GO:0005524 (13.9%) GO:0046872 (13.9%)" "pyrimidine nucleotide biosynthetic process (13.9%) L-arginine biosynthetic process (13.9%) glutamine metabolic process (13.9%)" cytoplasm (13.9%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.9%) ATP binding (13.9%) metal ion binding (13.9%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" AVATLHEGNMDGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025379 (100%) Protein of unknown function DUF4295 (100%) YANMMLALQGLLPDSNYPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (50%) GO:0016788 (46.7%) GO:0016787 (3.3%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (46.7%) hydrolase activity (3.3%)" "IPR000801 (17.2%) IPR005181 (17.2%) IPR050583 (17.2%)" "Esterase-like (17.2%) Sialate O-acetylesterase domain (17.2%) Mycobacterial A85 antigen (17.2%)" HELDPDGGYVVSVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (7.6%) IPR006101 (7.6%) IPR006102 (7.6%)" "Beta galactosidase small chain/ domain 5 (7.6%) Glycoside hydrolase, family 2 (7.6%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.6%)" EFAQLAFHYVGLELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (34%) "GO:0008446 (34%) GO:0070401 (32.1%)" 'de novo' GDP-L-fucose biosynthetic process (34%) "GDP-mannose 4,6-dehydratase activity (34%) NADP+ binding (32.1%)" "IPR006368 (34%) IPR016040 (34%) IPR036291 (32.1%)" "GDP-mannose 4,6-dehydratase (34%) NAD(P)-binding domain (34%) NAD(P)-binding domain superfamily (32.1%)" LFFTVQNPFLLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (14.1%) IPR023996 (14.1%) IPR039426 (14.1%)" "TonB-dependent receptor-like, beta-barrel (14.1%) TonB-dependent outer membrane protein, SusC/RagA (14.1%) TonB-dependent receptor-like (14.1%)" MQQAVDEMNEAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (32.3%) "GO:0016757 (32.3%) GO:0030246 (32.3%) GO:0016740 (3.2%)" carbohydrate metabolic process (32.3%) "glycosyltransferase activity (32.3%) carbohydrate binding (32.3%) transferase activity (3.2%)" "IPR010383 (13.1%) IPR033432 (13.1%) IPR037825 (13.1%)" "Glycosyl hydrolase 94, supersandwich domain (13.1%) Glycosyl hydrolase 94, catalytic domain (13.1%) Cellobiose phosphorylase, N-terminal (13.1%)" LSSQEAGLSNEEATEWQDGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.6%) IPR002772 (11.6%) IPR026891 (11.6%)" "Glycoside hydrolase, family 3, N-terminal (11.6%) Glycoside hydrolase family 3 C-terminal domain (11.6%) Fibronectin type III-like domain (11.6%)" VLLDFEQKPGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008270 (50%) GO:0016491 (50%)" "zinc ion binding (50%) oxidoreductase activity (50%)" "IPR002328 (16.7%) IPR011032 (16.7%) IPR013149 (16.7%)" "Alcohol dehydrogenase, zinc-type, conserved site (16.7%) GroES-like superfamily (16.7%) Alcohol dehydrogenase-like, C-terminal (16.7%)" WASFHSFAASWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.7%) IPR039426 (14.7%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.7%) TonB-dependent receptor-like (14.7%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" LYQVYLGDKLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" NFYSPLK root "2.3.1.- (33.3%) 3.4.-.- (33.3%) 5.6.2.1 (33.3%)" "Transferring groups other than amino-acyl groups (33.3%) Acting on peptide bonds (peptidases) (33.3%) DNA topoisomerase (33.3%)" "GO:0006508 (4.6%) GO:0006751 (4.6%) GO:0044038 (3.5%)" "GO:0005886 (3.8%) GO:0005737 (1.1%) GO:0005874 (0.5%)" "GO:0005524 (49.3%) GO:0046872 (4.6%) GO:0008233 (4.4%)" "proteolysis (4.6%) glutathione catabolic process (4.6%) cell wall macromolecule biosynthetic process (3.5%)" "plasma membrane (3.8%) cytoplasm (1.1%) microtubule (0.5%)" "ATP binding (49.3%) metal ion binding (4.6%) peptidase activity (4.4%)" "IPR018631 (29.8%) IPR012547 (26.7%) IPR027417 (23.2%)" "AAA-ATPase-like domain (29.8%) PD-(D/E)XK nuclease superfamily 9 (26.7%) P-loop containing nucleoside triphosphate hydrolase (23.2%)" LNPKPGASMGETEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006352 (16.9%) GO:0000428 (16.2%) "GO:0001216 (16.9%) GO:0003677 (16.9%) GO:0016987 (16.9%)" DNA-templated transcription initiation (16.9%) DNA-directed RNA polymerase complex (16.2%) "DNA-binding transcription activator activity (16.9%) DNA binding (16.9%) sigma factor activity (16.9%)" "IPR000394 (25.8%) IPR007046 (25.8%) IPR007634 (24.7%)" "RNA polymerase sigma factor 54 (25.8%) RNA polymerase sigma factor 54, core-binding domain (25.8%) RNA polymerase sigma factor 54, DNA-binding (24.7%)" TGLNFGGLK Bacteria Bacteria 4.2.3.4 (100%) 3-dehydroquinate synthase (100%) "GO:0008652 (13.1%) GO:0009073 (13.1%) GO:0009423 (12%)" "GO:0005737 (12%) GO:0005886 (4%) GO:0030313 (4%)" "GO:0003856 (13.1%) GO:0046872 (12.7%) GO:0000166 (11.9%)" "amino acid biosynthetic process (13.1%) aromatic amino acid family biosynthetic process (13.1%) chorismate biosynthetic process (12%)" "cytoplasm (12%) plasma membrane (4%) cell envelope (4%)" "3-dehydroquinate synthase activity (13.1%) metal ion binding (12.7%) nucleotide binding (11.9%)" "IPR030960 (17.1%) IPR050071 (17.1%) IPR056179 (17.1%)" "3-dehydroquinate synthase, N-terminal domain (17.1%) Dehydroquinate Synthase (17.1%) 3-dehydroquinate synthase, C-terminal domain (17.1%)" YLSDAQALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (33.3%) "GO:0008237 (33.3%) GO:0046872 (33.3%)" proteolysis (33.3%) "metallopeptidase activity (33.3%) metal ion binding (33.3%)" "IPR008754 (33.3%) IPR023852 (33.3%) IPR024079 (33.3%)" "Peptidase M43, pregnancy-associated plasma-A (33.3%) Metalloproteinase lipoprotein, BF0631 (33.3%) Metallopeptidase, catalytic domain superfamily (33.3%)" EDWFNASWVDNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QAVHGLLYFPADFDTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0140359 (50%) plasma membrane (50%) ABC-type transporter activity (50%) "IPR013525 (50%) IPR051449 (50%)" "ABC-2 type transporter, transmembrane domain (50%) ABC-2 integral membrane transporter component (50%)" KTFSVDSVVYSEEFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.- (40%) 2.1.1.173 (40%) 2.1.1.72 (20%)" "Methyltransferases (40%) 23S rRNA (guanine(2445)-N(2))-methyltransferase (40%) site-specific DNA-methyltransferase (adenine-specific) (20%)" "GO:0003723 (33.2%) GO:0070043 (33.2%) GO:0008990 (32.8%)" "RNA binding (33.2%) rRNA (guanine-N7-)-methyltransferase activity (33.2%) rRNA (guanine-N2-)-methyltransferase activity (32.8%)" "IPR000241 (17.5%) IPR004114 (17.5%) IPR054170 (17.5%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.5%) THUMP domain (17.5%) RlmL, ferredoxin-like domain (17.5%)" EDYDEAYENPLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016491 (33.3%) GO:0046872 (33.3%) GO:0051287 (33.3%)" "oxidoreductase activity (33.3%) metal ion binding (33.3%) NAD binding (33.3%)" IPR005255 (100%) PdxA family (100%) LGTTVYPNSFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.7%) IPR025896 (16.7%) IPR026906 (16.7%)" "Peptidase C10, streptopain (16.7%) Spi protease inhibitor (16.7%) BspA-type LRR region (16.7%)" ADVLLEDHMAK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (13%) GO:0015966 (12.2%)" "GO:0005737 (13%) GO:0070062 (12.2%) GO:1990742 (12.2%)" "GO:0004820 (13%) GO:0004081 (12.2%) GO:0005524 (12.2%)" "glycyl-tRNA aminoacylation (13%) diadenosine tetraphosphate biosynthetic process (12.2%)" "cytoplasm (13%) extracellular exosome (12.2%) microvesicle (12.2%)" "glycine-tRNA ligase activity (13%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.2%) ATP binding (12.2%)" "IPR027031 (11.8%) IPR002314 (11.1%) IPR002315 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.8%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Glycyl-tRNA synthetase (11.1%)" RWEDALAK root "2.1.1.72 (33.3%) 3.1.26.- (33.3%) 3.5.1.81 (33.3%)" "site-specific DNA-methyltransferase (adenine-specific) (33.3%) Endoribonucleases producing 5'-phosphomonoesters (33.3%) N-acyl-D-amino-acid deacylase (33.3%)" "GO:0006364 (12.1%) GO:0006952 (7.3%) GO:0006304 (0.8%)" "GO:0005737 (12.1%) GO:0016020 (7.3%) GO:0005829 (0.8%)" "GO:0003723 (12.1%) GO:0004540 (12.1%) GO:0016787 (12.1%)" "rRNA processing (12.1%) defense response (7.3%) DNA modification (0.8%)" "cytoplasm (12.1%) membrane (7.3%) cytosol (0.8%)" "RNA binding (12.1%) RNA nuclease activity (12.1%) hydrolase activity (12.1%)" "IPR003029 (19.5%) IPR004659 (19.5%) IPR019307 (19.5%)" "S1 domain (19.5%) Ribonuclease E/G (19.5%) RNA-binding protein AU-1/Ribonuclease E/G (19.5%)" LNSVAGGGFALSLLAQ Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" TYAVHNLDGLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" VNCKDEGGVALSTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" GLNVTLPYKEK root "1.1.1.25 (91.7%) 2.7.1.71 (8.3%)" "shikimate dehydrogenase (NADP(+)) (91.7%) shikimate kinase (8.3%)" "GO:0009423 (16.2%) GO:0019632 (16.2%) GO:0009073 (15.8%)" "GO:0005829 (15.3%) GO:0005737 (0.1%)" "GO:0004764 (16.3%) GO:0050661 (15.8%) GO:0000287 (0.5%)" "chorismate biosynthetic process (16.2%) shikimate metabolic process (16.2%) aromatic amino acid family biosynthetic process (15.8%)" "cytosol (15.3%) cytoplasm (0.1%)" "shikimate 3-dehydrogenase (NADP+) activity (16.3%) NADP binding (15.8%) magnesium ion binding (0.5%)" "IPR013708 (22.8%) IPR046346 (22.8%) IPR022893 (22.6%)" "Shikimate dehydrogenase substrate binding, N-terminal (22.8%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (22.8%) Shikimate dehydrogenase family (22.6%)" WLLAYGDALSQGGYYLASVANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0006465 (32.6%) GO:0006508 (1.1%)" GO:0016020 (32.6%) GO:0008236 (33.7%) "signal peptide processing (32.6%) proteolysis (1.1%)" membrane (32.6%) serine-type peptidase activity (33.7%) "IPR002142 (17.2%) IPR047217 (17.2%) IPR004634 (16.7%)" "Peptidase S49 (17.2%) Signal peptide peptidase A, N-terminal (17.2%) Peptidase S49, protease IV (16.7%)" MEVTLTTENFESYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045454 (33.3%) GO:0005829 (33.3%) GO:0015035 (33.3%) cell redox homeostasis (33.3%) cytosol (33.3%) protein-disulfide reductase activity (33.3%) "IPR005746 (25.9%) IPR013766 (25.9%) IPR017937 (25.9%)" "Thioredoxin (25.9%) Thioredoxin domain (25.9%) Thioredoxin, conserved site (25.9%)" YTLSQSDNNASNLMFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (31.6%) GO:0046677 (31.6%)" GO:0016020 (5.1%) GO:0008800 (31.6%) "beta-lactam antibiotic catabolic process (31.6%) response to antibiotic (31.6%)" membrane (5.1%) beta-lactamase activity (31.6%) "IPR000871 (25.8%) IPR045155 (25.8%) IPR023650 (24.7%)" "Beta-lactamase, class-A (25.8%) Beta-lactamase class A, catalytic domain (25.8%) Beta-lactamase, class-A active site (24.7%)" GDLRELDENGNTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.1%) GO:0043335 (15.7%) GO:0051083 (15.7%)" GO:0005737 (4.7%) "GO:0003755 (15.7%) GO:0043022 (15.7%) GO:0044183 (15.7%)" "protein transport (16.1%) protein unfolding (15.7%) 'de novo' cotranslational protein folding (15.7%)" cytoplasm (4.7%) "peptidyl-prolyl cis-trans isomerase activity (15.7%) ribosome binding (15.7%) protein folding chaperone (15.7%)" "IPR005215 (19%) IPR008881 (19%) IPR037041 (19%)" "Trigger factor (19%) Trigger factor, ribosome-binding, bacterial (19%) Trigger factor, C-terminal domain superfamily (19%)" VENAYLTGR root "GO:0006813 (27.3%) GO:0034728 (1.8%) GO:0140673 (1.8%)" "GO:0005886 (27.3%) GO:0016020 (9.1%) GO:0008023 (1.8%)" "GO:0008324 (27.3%) GO:0031491 (1.8%) GO:0042393 (1.8%)" "potassium ion transport (27.3%) nucleosome organization (1.8%) transcription elongation-coupled chromatin remodeling (1.8%)" "plasma membrane (27.3%) membrane (9.1%) transcription elongation factor complex (1.8%)" "monoatomic cation transmembrane transporter activity (27.3%) nucleosome binding (1.8%) histone binding (1.8%)" "IPR006037 (23.8%) IPR006512 (23.8%) IPR050144 (23.8%)" "Regulator of K+ conductance, C-terminal (23.8%) YidE/YbjL duplication (23.8%) AAE Transporter (23.8%)" LQFGNVALLPQVMAGVGGDSFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) LDLPVECGVNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (10%) IPR006103 (10%) IPR006104 (10%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (10%) Glycoside hydrolase family 2, catalytic domain (10%) Glycosyl hydrolases family 2, sugar binding domain (10%)" GSALVVAGGYGVGSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (16.7%) IPR014729 (16.7%) IPR014730 (16.7%)" "Electron transfer flavoprotein alpha subunit/FixB (16.7%) Rossmann-like alpha/beta/alpha sandwich fold (16.7%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (16.7%)" QSSNVLMFALTTDDGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009636 (24.6%) GO:0005886 (25.4%) "GO:0042910 (25.4%) GO:0015562 (24.6%)" response to toxic substance (24.6%) plasma membrane (25.4%) "xenobiotic transmembrane transporter activity (25.4%) efflux transmembrane transporter activity (24.6%)" "IPR001036 (33.6%) IPR027463 (33.6%) IPR004764 (32.7%)" "Acriflavin resistance protein (33.6%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.6%) Multidrug resistance protein MdtF-like (32.7%)" EVTVPLAFSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005975 (52.1%) "GO:0016787 (46.6%) GO:0016798 (1.4%)" carbohydrate metabolic process (52.1%) "hydrolase activity (46.6%) hydrolase activity, acting on glycosyl bonds (1.4%)" "IPR012878 (17.4%) IPR049046 (17.4%) IPR049049 (17.4%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17.4%)" RFHADASADYQNTFDAHSLYSQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" SLNPEWKK root "GO:0006654 (48.3%) GO:0046928 (1.1%)" GO:0030672 (1.1%) "GO:0003841 (48.3%) GO:0005509 (1.1%)" "phosphatidic acid biosynthetic process (48.3%) regulation of neurotransmitter secretion (1.1%)" synaptic vesicle membrane (1.1%) "1-acylglycerol-3-phosphate O-acyltransferase activity (48.3%) calcium ion binding (1.1%)" "IPR002123 (91.5%) IPR000008 (2.1%) IPR013583 (2.1%)" "Phospholipid/glycerol acyltransferase (91.5%) C2 domain (2.1%) Multiple C2 domain and Transmembrane region Proteins, C-terminal (2.1%)" TAPMFVSR Bacteria Bacteria "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.9%) GO:0016020 (0.3%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.9%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.9%) membrane (0.3%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.9%)" "IPR001264 (16.9%) IPR001460 (16.9%) IPR050396 (16.9%)" "Glycosyl transferase, family 51 (16.9%) Penicillin-binding protein, transpeptidase (16.9%) Glycosyltransferase 51/Transpeptidase (16.9%)" MAAELLPFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0052689 (100%) carboxylic ester hydrolase activity (100%) "IPR037461 (20.4%) IPR040794 (20.4%) IPR052762 (20.4%)" "CtCE2-like domain (20.4%) Carbohydrate esterase 2, N-terminal (20.4%) Plant cell wall deacetylase/carbohydrate esterase (20.4%)" GELFNCQTTVENEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006004 (31.8%) GO:0005996 (1.5%)" GO:0005737 (33.3%) "GO:0008736 (31.8%) GO:0016861 (1.5%)" "fucose metabolic process (31.8%) monosaccharide metabolic process (1.5%)" cytoplasm (33.3%) "L-fucose isomerase activity (31.8%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1.5%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" MWNEGTLNEER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) LSLEDDNALGEVVVVGYGQQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.9%) IPR012910 (14.9%) IPR023996 (14.9%)" "Carboxypeptidase-like, regulatory domain superfamily (14.9%) TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%)" FHDAPVTLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.6%) IPR002942 (11.6%) IPR006145 (11.6%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.6%) RNA-binding S4 domain (11.6%) Pseudouridine synthase, RsuA/RluA-like (11.6%)" DSVLAALPLGYADGLNRR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (20%) "GO:0005524 (20%) GO:0008784 (20%) GO:0016881 (20%)" D-alanine biosynthetic process (20%) "ATP binding (20%) alanine racemase activity (20%) acid-amino acid ligase activity (20%)" "IPR000821 (10.2%) IPR001608 (10.2%) IPR011079 (10.2%)" "Alanine racemase (10.2%) Alanine racemase, N-terminal (10.2%) Alanine racemase, C-terminal (10.2%)" NAPELLKPETGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.6.4.13 (95.5%) 3.6.4.- (4.5%)" "RNA helicase (95.5%) Acting on ATP; involved in cellular and subcellular movement (4.5%)" GO:0005829 (10.6%) "GO:0003724 (22.2%) GO:0005524 (22.2%) GO:0016787 (22.2%)" cytosol (10.6%) "RNA helicase activity (22.2%) ATP binding (22.2%) hydrolase activity (22.2%)" "IPR000629 (10.2%) IPR001650 (10.2%) IPR005580 (10.2%)" "ATP-dependent RNA helicase DEAD-box, conserved site (10.2%) Helicase, C-terminal domain-like (10.2%) DEAD box helicase DbpA/CsdA, RNA-binding domain (10.2%)" KDYDVEHLLNLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.1.1.96 (95%) 4.1.1.- (5%)" "carboxynorspermidine decarboxylase (95%) Carboxy-lyases (5%)" "GO:0009089 (25.6%) GO:0008295 (24.4%) GO:0045312 (24.4%)" GO:0008836 (25.6%) "lysine biosynthetic process via diaminopimelate (25.6%) spermidine biosynthetic process (24.4%) nor-spermidine biosynthetic process (24.4%)" diaminopimelate decarboxylase activity (25.6%) "IPR009006 (25.3%) IPR022643 (25.3%) IPR029066 (25.3%)" "Alanine racemase/group IV decarboxylase, C-terminal (25.3%) Orn/DAP/Arg decarboxylase 2, C-terminal (25.3%) PLP-binding barrel (25.3%)" TGANQLLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0007059 (19.6%) GO:0051301 (19.6%)" GO:0005886 (19.6%) "GO:0003677 (20.6%) GO:0005524 (20.6%)" "chromosome segregation (19.6%) cell division (19.6%)" plasma membrane (19.6%) "DNA binding (20.6%) ATP binding (20.6%)" "IPR002543 (12.7%) IPR018541 (12.7%) IPR050206 (12.7%)" "FtsK domain (12.7%) FtsK gamma domain (12.7%) FtsK/SpoIIIE/SftA cell division and DNA translocation (12.7%)" ELLNLAAK root "2.7.1.71 (25%) 1.4.1.14 (16.7%) 2.3.2.27 (16.7%)" "shikimate kinase (25%) glutamate synthase (NADH) (16.7%) RING-type E3 ubiquitin transferase (16.7%)" "GO:0000707 (1.5%) GO:0007131 (1.5%) GO:0006402 (1.2%)" "GO:0016020 (4.5%) GO:0005829 (2.5%) GO:0005737 (2.2%)" "GO:0016301 (24.2%) GO:0005524 (4.2%) GO:0046872 (2.5%)" "meiotic DNA recombinase assembly (1.5%) reciprocal meiotic recombination (1.5%) mRNA catabolic process (1.2%)" "membrane (4.5%) cytosol (2.5%) cytoplasm (2.2%)" "kinase activity (24.2%) ATP binding (4.2%) metal ion binding (2.5%)" "IPR027417 (25%) IPR011009 (1.7%) IPR004147 (1.5%)" "P-loop containing nucleoside triphosphate hydrolase (25%) Protein kinase-like domain superfamily (1.7%) ABC1 atypical kinase-like domain (1.5%)" SKETLLGLVYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LPVFVPEGSLLPVGPEMEWSDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" ALGLLNLFGNASFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) VADLLEREVFDFVGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" DTENDTVTGFNLGADDYLSKPFSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (16.7%) IPR001867 (16.7%) IPR039420 (16.7%)" "Signal transduction response regulator, receiver domain (16.7%) OmpR/PhoB-type DNA-binding domain (16.7%) Transcriptional regulatory protein WalR-like (16.7%)" AGEYLQSVNEYAVYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.3%) IPR051802 (19.3%) IPR002890 (18.8%)" "Alpha-2-macroglobulin (19.3%) Alpha-2-macroglobulin-like (19.3%) Macroglobulin domain (18.8%)" WDDVDNMQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (26.9%) IPR014756 (26.9%) IPR040475 (26.9%)" "Immunoglobulin-like fold (26.9%) Immunoglobulin E-set (26.9%) Surface glycan-binding protein B, xyloglucan binding domain (26.9%)" DLAEALADLKPR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR010720 (16.6%) IPR017853 (16.6%) IPR051563 (16.6%)" "Alpha-L-arabinofuranosidase, C-terminal (16.6%) Glycoside hydrolase superfamily (16.6%) Glycosyl Hydrolase Family 51 (16.6%)" LRGGASLNASNDPLYVLDGLALDNNTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" NVENMLDLFGDEEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.6%) GO:0004356 (51.4%) glutamine biosynthetic process (48.6%) glutamine synthetase activity (51.4%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" SAVDLSGTLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (53.6%) IPR042278 (46.4%)" "Fimbrillin-like 1 (53.6%) Fimbrillin-like 1, N-terminal (46.4%)" QLNFEEAAELAYFGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.5%) GO:0009090 (17.5%) GO:0009088 (12.7%)" GO:0005829 (17.5%) "GO:0004072 (17.5%) GO:0005524 (17.5%)" "lysine biosynthetic process via diaminopimelate (17.5%) homoserine biosynthetic process (17.5%) threonine biosynthetic process (12.7%)" cytosol (17.5%) "aspartate kinase activity (17.5%) ATP binding (17.5%)" "IPR001048 (14.2%) IPR001341 (14.2%) IPR005260 (14.2%)" "Aspartate/glutamate/uridylate kinase (14.2%) Aspartate kinase (14.2%) Aspartate kinase, monofunctional class (14.2%)" MYPNYLSSEAVLASENVFFSDYHAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016798 (50%) GO:0030246 (50%)" "hydrolase activity, acting on glycosyl bonds (50%) carbohydrate binding (50%)" "IPR013780 (12.5%) IPR013785 (12.5%) IPR014718 (12.5%)" "Glycosyl hydrolase, all-beta (12.5%) Aldolase-type TIM barrel (12.5%) Glycoside hydrolase-type carbohydrate-binding (12.5%)" FGTDSENGVTVTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (45.5%) "GO:0052689 (45.5%) GO:0004557 (9.1%)" cell outer membrane (45.5%) "carboxylic ester hydrolase activity (45.5%) alpha-galactosidase activity (9.1%)" "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" SYAEAEALVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (42.6%) IPR011990 (40.4%) IPR050498 (17%)" "Tetratricopeptide repeat (42.6%) Tetratricopeptide-like helical domain superfamily (40.4%) Photosystem I assembly protein Ycf3 (17%)" YYDEQTPALYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (11.9%) IPR012910 (11.9%) IPR023996 (11.9%)" "Carboxypeptidase-like, regulatory domain superfamily (11.9%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" DADLDAVLK root "2.4.2.7 (50%) 3.1.2.- (50%)" "adenine phosphoribosyltransferase (50%) Thiolester hydrolases (50%)" "GO:0007165 (13%) GO:0006107 (2.2%) GO:0006166 (2.2%)" "GO:0005856 (13%) GO:0016020 (13%) GO:0009279 (10.9%)" "GO:0009882 (8.7%) GO:0071111 (8.7%) GO:0071949 (8.7%)" "signal transduction (13%) oxaloacetate metabolic process (2.2%) purine ribonucleoside salvage (2.2%)" "cytoskeleton (13%) membrane (13%) cell outer membrane (10.9%)" "blue light photoreceptor activity (8.7%) cyclic-guanylate-specific phosphodiesterase activity (8.7%) FAD binding (8.7%)" "IPR000488 (7.1%) IPR000906 (7.1%) IPR002110 (7.1%)" "Death domain (7.1%) ZU5 domain (7.1%) Ankyrin repeat (7.1%)" VLKPLEFFGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR000595 (14.7%) IPR012318 (14.7%) IPR050397 (14.7%)" "Cyclic nucleotide-binding domain (14.7%) Crp-type HTH domain (14.7%) Global Transcriptional Regulators in Environmental Response (14.7%)" YYDAGLYQPEQSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR041700 (56%) IPR037066 (42%) IPR036942 (2%)" "Outer membrane protein beta-barrel domain 3 (56%) TonB-dependent receptor, plug domain superfamily (42%) TonB-dependent receptor-like, beta-barrel domain superfamily (2%)" VPAWNDEGTLTNEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (34%) GO:0005737 (31.9%) GO:0008734 (34%) 'de novo' NAD+ biosynthetic process from L-aspartate (34%) cytoplasm (31.9%) L-aspartate oxidase activity (34%) "IPR003953 (17.2%) IPR005288 (17.2%) IPR015939 (17.2%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17.2%) L-aspartate oxidase (17.2%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (17.2%)" EGNPGEAVASVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR007621 (100%) TPM domain (100%) KSDVTGALAHLDSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.6%) IPR023996 (13.6%) IPR023997 (13.6%)" "TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.6%)" TLQRDEEELLQVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (32.7%) GO:0016020 (34.7%) GO:0003677 (32.7%) regulation of DNA-templated transcription (32.7%) membrane (34.7%) DNA binding (32.7%) "IPR016032 (47.1%) IPR036388 (47.1%) IPR000792 (5.9%)" "Signal transduction response regulator, C-terminal effector (47.1%) Winged helix-like DNA-binding domain superfamily (47.1%) Transcription regulator LuxR, C-terminal (5.9%)" KDLDWSNLSFGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (12.6%) GO:0009098 (12.6%) GO:0009099 (12.6%)" "GO:0004084 (17.1%) GO:0052654 (7.2%) GO:0052655 (7.2%)" "isoleucine biosynthetic process (12.6%) L-leucine biosynthetic process (12.6%) L-valine biosynthetic process (12.6%)" "branched-chain-amino-acid transaminase activity (17.1%) L-leucine-2-oxoglutarate transaminase activity (7.2%) L-valine-2-oxoglutarate transaminase activity (7.2%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" MGNKAEALTLVNEVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" QGNTWSTLTVSNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR004564 (51.6%) IPR029046 (48.4%)" "Outer membrane lipoprotein carrier protein LolA-like (51.6%) Lipoprotein localisation LolA/LolB/LppX (48.4%)" YASNLVYVNHANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0015079 (33.3%) GO:0015293 (33.3%)" plasma membrane (33.3%) "potassium ion transmembrane transporter activity (33.3%) symporter activity (33.3%)" "IPR003855 (25%) IPR023051 (25%) IPR053951 (25%)" "Potassium transporter (25%) Low affinity potassium transport system protein Kup (25%) K+ potassium transporter, integral membrane domain (25%)" GLAECNPSENLTTNKDNLLEELLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.8%) IPR012944 (34.8%) IPR033985 (30.4%)" "Tetratricopeptide-like helical domain superfamily (34.8%) RagB/SusD domain (34.8%) SusD-like, N-terminal (30.4%)" VNYNWDDLLLASFTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LPLNVFTCVTGVSGSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006289 (12.3%) GO:0006281 (0.4%)" "GO:0005737 (12.6%) GO:0009380 (12.3%)" "GO:0003677 (12.6%) GO:0004518 (12.6%) GO:0005524 (12.6%)" "nucleotide-excision repair (12.3%) DNA repair (0.4%)" "cytoplasm (12.6%) excinuclease repair complex (12.3%)" "DNA binding (12.6%) nuclease activity (12.6%) ATP binding (12.6%)" "IPR003439 (17.1%) IPR004602 (17.1%) IPR041102 (17.1%)" "ABC transporter-like, ATP-binding domain (17.1%) UvrABC system subunit A (17.1%) UvrA, interaction domain (17.1%)" VNAVCPGTLATSFHDLFNTPENR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.47 (100%) glucose 1-dehydrogenase [NAD(P)(+)] (100%) GO:0016491 (100%) oxidoreductase activity (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" DRVDALLVAWQPGLEGGNSVADLLTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (50%) "GO:0004553 (48.8%) GO:0008422 (1.2%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.8%) beta-glucosidase activity (1.2%)" "IPR002772 (13%) IPR050288 (13%) IPR001764 (12.7%)" "Glycoside hydrolase family 3 C-terminal domain (13%) Cellulose-degrading glycosyl hydrolase 3 (13%) Glycoside hydrolase, family 3, N-terminal (12.7%)" NQAFDELFKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) LLLAEFLGLEQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009267 (50%) GO:0005886 (50%) cellular response to starvation (50%) plasma membrane (50%) "IPR003706 (50%) IPR051605 (50%)" "CstA, N-terminal domain (50%) Peptide Transporter Carbon Starvation (50%)" SDKTLVGTYQYGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.4%) IPR012910 (20.4%) IPR008969 (19.7%)" "TonB-dependent receptor-like, beta-barrel (20.4%) TonB-dependent receptor, plug domain (20.4%) Carboxypeptidase-like, regulatory domain superfamily (19.7%)" YNDSGATYVMDAGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ATDVTNYLFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (20%) GO:0042026 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0016887 (20%)" "cellular response to heat (20%) protein refolding (20%)" cytoplasm (20%) "ATP binding (20%) ATP hydrolysis activity (20%)" "IPR004176 (8.8%) IPR003593 (8.4%) IPR003959 (8.4%)" "Clp, repeat (R) N-terminal domain (8.8%) AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%)" SEFENVLDVLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" GEDTSTNPMATLFAWSGALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20%) GO:0006102 (20%)" "GO:0000287 (20%) GO:0004450 (20%) GO:0051287 (20%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "magnesium ion binding (20%) isocitrate dehydrogenase (NADP+) activity (20%) NAD binding (20%)" "IPR004790 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" DKNVYELSYNNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005976 (50%) GO:0052689 (50%) polysaccharide metabolic process (50%) carboxylic ester hydrolase activity (50%) "IPR008391 (34%) IPR039069 (34%) IPR029058 (32%)" "Acetyl xylan esterase domain (34%) Carbohydrate esterase 7 family (34%) Alpha/Beta hydrolase fold (32%)" ELLQDEVMAAVAHTEALMNSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25.3%) GO:0016301 (25.3%) GO:0050242 (25.3%)" "ATP binding (25.3%) kinase activity (25.3%) pyruvate, phosphate dikinase activity (25.3%)" "IPR002192 (10.3%) IPR010121 (10.3%) IPR013815 (10.3%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (10.3%) Pyruvate, phosphate dikinase (10.3%) ATP-grasp fold, subdomain 1 (10.3%)" GNPYFLDFQGGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (64.3%) GO:0016740 (32.9%) GO:0016301 (2.9%)" "ATP binding (64.3%) transferase activity (32.9%) kinase activity (2.9%)" "IPR002575 (25.4%) IPR005337 (24.9%) IPR011009 (24.9%)" "Aminoglycoside phosphotransferase (25.4%) RapZ-like family (24.9%) Protein kinase-like domain superfamily (24.9%)" FYLTALGEYGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR043864 (27.1%) IPR016035 (24.8%) IPR002641 (24%)" "OMP85-like, membrane spanning beta-barrel domain (27.1%) Acyl transferase/acyl hydrolase/lysophospholipase (24.8%) Patatin-like phospholipase domain (24%)" YQGYSLDTPAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (23.1%) IPR057601 (23.1%) IPR008969 (17.9%)" "TonB-dependent receptor-like (23.1%) TonB-dependent transporter Oar-like, beta-barrel domain (23.1%) Carboxypeptidase-like, regulatory domain superfamily (17.9%)" WLVFPLK root 2.7.1.137 (100%) phosphatidylinositol 3-kinase (100%) "GO:0006298 (16.6%) GO:0000045 (0.1%) GO:0006281 (0.1%)" "GO:0005829 (16.6%) GO:0016020 (0.3%) GO:0000407 (0.1%)" "GO:0005524 (16.7%) GO:0030983 (16.6%) GO:0140664 (16.6%)" "mismatch repair (16.6%) autophagosome assembly (0.1%) DNA repair (0.1%)" "cytosol (16.6%) membrane (0.3%) phagophore assembly site (0.1%)" "ATP binding (16.7%) mismatched DNA binding (16.6%) ATP-dependent DNA damage sensor activity (16.6%)" "IPR007696 (8.6%) IPR045076 (8.6%) IPR007860 (8.4%)" "DNA mismatch repair protein MutS, core (8.6%) DNA mismatch repair MutS (8.6%) DNA mismatch repair protein MutS, connector domain (8.4%)" LMSGVPGVNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.4%) GO:0005886 (25.4%) "GO:0000286 (25.4%) GO:0000166 (23.8%)" L-alanine catabolic process (25.4%) plasma membrane (25.4%) "alanine dehydrogenase activity (25.4%) nucleotide binding (23.8%)" "IPR007698 (20.3%) IPR007886 (20.3%) IPR008141 (20.3%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20.3%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20.3%) Alanine dehydrogenase (20.3%)" LAQNLGLGAQWDGFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" YGTFPAMSVGWVVSDEPFFKPLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (11.9%) IPR012910 (11.9%) IPR023996 (11.9%)" "Carboxypeptidase-like, regulatory domain superfamily (11.9%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" YQALLAGCFLSNPVEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.3%) IPR027304 (25.3%) IPR046357 (25.3%)" "Periplasmic chaperone PpiD (26.3%) Trigger factor/SurA domain superfamily (25.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.3%)" HEEMPEGSYTTSLFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.4.19 (50%) 3.6.1.31 (50%)" "phosphoribosyl-AMP cyclohydrolase (50%) phosphoribosyl-ATP diphosphatase (50%)" GO:0000105 (20%) GO:0005737 (20%) "GO:0004635 (20%) GO:0004636 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "phosphoribosyl-AMP cyclohydrolase activity (20%) phosphoribosyl-ATP diphosphatase activity (20%) ATP binding (20%)" "IPR002496 (20%) IPR008179 (20%) IPR021130 (20%)" "Phosphoribosyl-AMP cyclohydrolase domain (20%) Phosphoribosyl-ATP pyrophosphohydrolase (20%) Phosphoribosyl-ATP pyrophosphohydrolase-like (20%)" NLDELRQDLEK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34%) IPR050337 (34%) IPR036237 (32%)" "Rhamnose isomerase (34%) L-rhamnose isomerase (34%) Xylose isomerase-like superfamily (32%)" LLAENQNQLVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000160 (25.4%) GO:0006355 (25.4%)" GO:0016020 (23.7%) GO:0003677 (25.4%) "phosphorelay signal transduction system (25.4%) regulation of DNA-templated transcription (25.4%)" membrane (23.7%) DNA binding (25.4%) "IPR001867 (34.9%) IPR016032 (32.6%) IPR036388 (32.6%)" "OmpR/PhoB-type DNA-binding domain (34.9%) Signal transduction response regulator, C-terminal effector (32.6%) Winged helix-like DNA-binding domain superfamily (32.6%)" YSGVLSTK root "2.7.13.3 (33.3%) 2.7.7.65 (33.3%) 3.2.1.21 (33.3%)" "histidine kinase (33.3%) diguanylate cyclase (33.3%) beta-glucosidase (33.3%)" "GO:0008202 (6.7%) GO:0006508 (3.3%) GO:0007165 (3.3%)" "GO:0009279 (16.7%) GO:0005634 (3.3%) GO:0005737 (3.3%)" "GO:0016491 (6.7%) GO:0016791 (6.7%) GO:0000155 (3.3%)" "steroid metabolic process (6.7%) proteolysis (3.3%) signal transduction (3.3%)" "cell outer membrane (16.7%) nucleus (3.3%) cytoplasm (3.3%)" "oxidoreductase activity (6.7%) phosphatase activity (6.7%) phosphorelay sensor kinase activity (3.3%)" "IPR012910 (7.2%) IPR023996 (7.2%) IPR023997 (7.2%)" "TonB-dependent receptor, plug domain (7.2%) TonB-dependent outer membrane protein, SusC/RagA (7.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (7.2%)" LWLLDDNKDTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR040572 (100%) Thaumarchaeal output domain 1 (100%) GDGTFGDLMLTYNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006457 (30.8%) GO:0042026 (13.5%)" GO:0005737 (11.5%) GO:0051082 (44.2%) "protein folding (30.8%) protein refolding (13.5%)" cytoplasm (11.5%) unfolded protein binding (44.2%) "IPR002939 (22.6%) IPR008971 (21.7%) IPR001623 (20.8%)" "Chaperone DnaJ, C-terminal (22.6%) HSP40/DnaJ peptide-binding (21.7%) DnaJ domain (20.8%)" GPQVLAENKDDDE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" VKEHSFTALAGMESWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" DVTATTPVANSLMTLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (34.4%) IPR034982 (34.4%) IPR038352 (31.3%)" "Imelysin-like domain (34.4%) Iron-regulated protein A, imelysin-like domain (34.4%) Imelysin-like domain superfamily (31.3%)" WVAQCCDLQDAPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.4%) IPR015883 (17.4%) IPR025705 (17.4%)" "PA14 domain (17.4%) Glycoside hydrolase family 20, catalytic domain (17.4%) Beta-hexosaminidase (17.4%)" SLFVSTLQAYFEGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (80%) GO:0003676 (20%)" "ATP binding (80%) nucleic acid binding (20%)" "IPR018631 (33.3%) IPR012547 (31.7%) IPR027417 (30.2%)" "AAA-ATPase-like domain (33.3%) PD-(D/E)XK nuclease superfamily 9 (31.7%) P-loop containing nucleoside triphosphate hydrolase (30.2%)" VPAEALYGVQTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.3.1.1 (100%) aspartate ammonia-lyase (100%) "GO:0006099 (25%) GO:0006531 (25%)" GO:0005829 (25%) GO:0008797 (25%) "tricarboxylic acid cycle (25%) aspartate metabolic process (25%)" cytosol (25%) aspartate ammonia-lyase activity (25%) "IPR000362 (14.3%) IPR008948 (14.3%) IPR018951 (14.3%)" "Fumarate lyase family (14.3%) L-Aspartase-like (14.3%) Fumarase C, C-terminal (14.3%)" VTEETTTAVSTNNPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" TLSFPELR root "2.4.2.10 (97%) 6.2.1.12 (3%)" "orotate phosphoribosyltransferase (97%) 4-coumarate--CoA ligase (3%)" "GO:0019856 (16.2%) GO:0044205 (16.2%) GO:0006113 (1.5%)" "GO:0016020 (2.3%) GO:0005634 (1.5%) GO:0005886 (1.5%)" "GO:0000287 (16.2%) GO:0004588 (16.2%) GO:0050839 (1.5%)" "pyrimidine nucleobase biosynthetic process (16.2%) 'de novo' UMP biosynthetic process (16.2%) fermentation (1.5%)" "membrane (2.3%) nucleus (1.5%) plasma membrane (1.5%)" "magnesium ion binding (16.2%) orotate phosphoribosyltransferase activity (16.2%) cell adhesion molecule binding (1.5%)" "IPR000836 (14.2%) IPR004467 (14.2%) IPR023031 (14.2%)" "Phosphoribosyltransferase domain (14.2%) Orotate phosphoribosyl transferase domain (14.2%) Orotate phosphoribosyltransferase (14.2%)" SEGLFGVPMGDLSTYLTMNASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) WVYYKDGSSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR033427 (29.6%) IPR011050 (27.8%) IPR003961 (11.1%)" "Domain of unknown function DUF5123 (29.6%) Pectin lyase fold/virulence factor (27.8%) Fibronectin type III (11.1%)" ECPWATLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.2.7.7 (60%) 1.2.7.1 (20%) 1.2.7.3 (20%)" "3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (60%) pyruvate synthase (20%) 2-oxoglutarate synthase (20%)" "GO:0016491 (92.7%) GO:0019164 (2.4%) GO:0043807 (2.4%)" "oxidoreductase activity (92.7%) pyruvate synthase activity (2.4%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity (2.4%)" "IPR002880 (20%) IPR009014 (20%) IPR029061 (20%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (20%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (20%) Thiamin diphosphate-binding fold (20%)" FYYVEEGCWLSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001383 (25%) IPR026569 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL28, bacteria (25%) Large ribosomal subunit protein bL28 (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" LLDEAVEWCR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR023214 (34.1%) IPR036412 (34.1%) IPR016769 (31.7%)" "HAD superfamily (34.1%) HAD-like superfamily (34.1%) Bacteriophage SP01, Orf1 (31.7%)" SDYVVLEADEFDR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.3.2.8 (100%) UDP-N-acetylmuramate--L-alanine ligase (100%) "GO:0008360 (13.3%) GO:0009252 (13.3%) GO:0051301 (13.3%)" "GO:0005737 (13.2%) GO:0016020 (6.2%)" "GO:0005524 (13.6%) GO:0008763 (13.2%) GO:0016881 (0.4%)" "regulation of cell shape (13.3%) peptidoglycan biosynthetic process (13.3%) cell division (13.3%)" "cytoplasm (13.2%) membrane (6.2%)" "ATP binding (13.6%) UDP-N-acetylmuramate-L-alanine ligase activity (13.2%) acid-amino acid ligase activity (0.4%)" "IPR013221 (14.4%) IPR036565 (14.4%) IPR050061 (14.4%)" "Mur ligase, central (14.4%) Mur-like, catalytic domain superfamily (14.4%) Peptidoglycan biosynthesis MurCDEF (14.4%)" VHSSCATGDLLGSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.4.25 (50.6%) 4.1.99.12 (49.4%)" "GTP cyclohydrolase II (50.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (49.4%)" GO:0009231 (12.6%) GO:0005829 (12.6%) "GO:0003935 (12.6%) GO:0005525 (12.6%) GO:0008686 (12.6%)" riboflavin biosynthetic process (12.6%) cytosol (12.6%) "GTP cyclohydrolase II activity (12.6%) GTP binding (12.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase activity (12.6%)" "IPR000422 (16.7%) IPR000926 (16.7%) IPR017945 (16.7%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.7%) GTP cyclohydrolase II, RibA (16.7%) DHBP synthase RibB-like alpha/beta domain superfamily (16.7%)" EAAQFYLSLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.6%) GO:0008295 (19.6%) GO:0033388 (19.6%)" "GO:0008792 (19.6%) GO:0046872 (19.6%) GO:0004497 (1.8%)" "L-arginine catabolic process (19.6%) spermidine biosynthetic process (19.6%) putrescine biosynthetic process from arginine (19.6%)" "arginine decarboxylase activity (19.6%) metal ion binding (19.6%) monooxygenase activity (1.8%)" "IPR000183 (11.1%) IPR002985 (11.1%) IPR009006 (11.1%)" "Ornithine/DAP/Arg decarboxylase (11.1%) Arginine decarboxylase (11.1%) Alanine racemase/group IV decarboxylase, C-terminal (11.1%)" GLTPMLNSATLSGDNLGVDDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LSWTGTGSSASDWALLSTFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" VNGDDAAPLFK root "1.-.-.- (50%) 1.11.1.- (50%)" "Oxidoreductases (50%) Peroxidases (50%)" "GO:0034599 (39.3%) GO:0006979 (10.7%)" GO:0004601 (50%) "cellular response to oxidative stress (39.3%) response to oxidative stress (10.7%)" peroxidase activity (50%) "IPR000889 (29.8%) IPR036249 (29.8%) IPR029760 (27.7%)" "Glutathione peroxidase (29.8%) Thioredoxin-like superfamily (29.8%) Glutathione peroxidase conserved site (27.7%)" FVPASGAASR Bacteria Bacteria "2.7.1.22 (90%) 2.7.7.1 (10%)" "ribosylnicotinamide kinase (90%) nicotinamide-nucleotide adenylyltransferase (10%)" GO:0016020 (2.1%) "GO:0016301 (66.3%) GO:0016779 (23.2%) GO:0050262 (8.4%)" membrane (2.1%) "kinase activity (66.3%) nucleotidyltransferase activity (23.2%) ribosylnicotinamide kinase activity (8.4%)" "IPR025393 (43.9%) IPR029044 (42.7%) IPR027417 (4.5%)" "Domain of unknown function DUF4301 (43.9%) Nucleotide-diphospho-sugar transferases (42.7%) P-loop containing nucleoside triphosphate hydrolase (4.5%)" DKLLEGAANFDDEVMELYLDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (20%) GO:0005737 (20%) "GO:0003746 (20%) GO:0003924 (20%) GO:0005525 (20%)" ribosome disassembly (20%) cytoplasm (20%) "translation elongation factor activity (20%) GTPase activity (20%) GTP binding (20%)" "IPR000640 (6.4%) IPR000795 (6.4%) IPR004161 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translational (tr)-type GTP-binding domain (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%)" QNVLETTLTPEEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.5%) GO:0008360 (12.5%) GO:0009252 (12.5%)" GO:0005886 (12.5%) GO:0050511 (12.5%) "carbohydrate metabolic process (12.5%) regulation of cell shape (12.5%) peptidoglycan biosynthetic process (12.5%)" plasma membrane (12.5%) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.5%) "IPR004276 (33.3%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.3%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" DPVADAQGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (17%) "GO:0005886 (16%) GO:0016020 (1.1%)" "GO:0016655 (17%) GO:0051537 (17%) GO:0009055 (16%)" sodium ion transport (17%) "plasma membrane (16%) membrane (1.1%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (17%) 2 iron, 2 sulfur cluster binding (17%) electron transfer activity (16%)" "IPR001433 (10.1%) IPR001709 (10.1%) IPR008333 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" QGVQLAHLAAGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.1.3.- (50%) 5.1.3.14 (50%)" "Acting on carbohydrates and derivatives (50%) UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) (50%)" "GO:0016853 (96.2%) GO:0008761 (3.8%)" "isomerase activity (96.2%) UDP-N-acetylglucosamine 2-epimerase activity (3.8%)" "IPR003331 (50%) IPR029767 (50%)" "UDP-N-acetylglucosamine 2-epimerase domain (50%) UDP-N-acetylglucosamine 2-epimerase WecB-like (50%)" LSGYGMTQYQYSGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.6%) IPR023614 (48.4%)" "Phosphate-selective porin O/P (51.6%) Porin domain superfamily (48.4%)" ETLPPCSLTMGLATLLSAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.99.6 (92.3%) 3.1.1.31 (7.7%)" "glucosamine-6-phosphate deaminase (92.3%) 6-phosphogluconolactonase (7.7%)" "GO:0005975 (33.3%) GO:0006044 (33.3%)" GO:0004342 (33.3%) "carbohydrate metabolic process (33.3%) N-acetylglucosamine metabolic process (33.3%)" glucosamine-6-phosphate deaminase activity (33.3%) "IPR052960 (17.3%) IPR003737 (16.8%) IPR004547 (16.8%)" "Glucosamine-6-phosphate deaminase-like (17.3%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (16.8%) Glucosamine-6-phosphate isomerase (16.8%)" TTWHDATFWSVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (32.2%) GO:0051536 (1.1%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (32.2%) iron-sulfur cluster binding (1.1%)" "IPR003741 (14.5%) IPR004452 (14.5%) IPR017896 (14.5%)" "LUD domain (14.5%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.5%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.5%)" GELELTTVNQEFLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.24 (100%) glucose-1-phosphate thymidylyltransferase (100%) "GO:0008879 (50%) GO:0046872 (49.6%) GO:0016779 (0.4%)" "glucose-1-phosphate thymidylyltransferase activity (50%) metal ion binding (49.6%) nucleotidyltransferase activity (0.4%)" "IPR005835 (33.5%) IPR005907 (33.5%) IPR029044 (33%)" "Nucleotidyl transferase domain (33.5%) Glucose-1-phosphate thymidylyltransferase, short form (33.5%) Nucleotide-diphospho-sugar transferases (33%)" KADGVTAWLVPGSWLVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.3%) IPR004430 (14.3%) IPR015931 (14.3%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.3%) 3-isopropylmalate dehydratase, large subunit (14.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (14.3%)" EKVELALANGLK Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.6%) GO:0006096 (12.6%) GO:0019563 (12.6%)" "GO:0005829 (12.6%) GO:0016020 (12.3%)" GO:0004807 (12.6%) "gluconeogenesis (12.6%) glycolytic process (12.6%) glycerol catabolic process (12.6%)" "cytosol (12.6%) membrane (12.3%)" triose-phosphate isomerase activity (12.6%) "IPR000652 (17%) IPR020861 (17%) IPR009908 (16.7%)" "Triosephosphate isomerase (17%) Triosephosphate isomerase, active site (17%) Methylamine utilisation protein, MauE (16.7%)" AKDEFMSQVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (32%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (32%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" EMYGNTWTPDRTDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.7%) IPR039426 (15.7%) IPR012910 (14.2%)" "TonB-dependent outer membrane protein, SusC/RagA (15.7%) TonB-dependent receptor-like (15.7%) TonB-dependent receptor, plug domain (14.2%)" MQALQEMQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (16.9%) IPR019998 (16.9%) IPR028053 (16.9%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (16.9%) Membrane insertase YidC (16.9%) Membrane insertase YidC, N-terminal (16.9%)" ADMYADFFSNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" MEWLALTEEHPEGEVWEHCQTLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GFDLTVFGTGSAGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.7%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.7%)" DTPQQMTETDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) ATANYNHTFAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GTLFLDEVGELPLQTQAR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006355 (33.3%) "GO:0005524 (33.3%) GO:0043565 (32.4%) GO:0003677 (1%)" regulation of DNA-templated transcription (33.3%) "ATP binding (33.3%) sequence-specific DNA binding (32.4%) DNA binding (1%)" "IPR002078 (13%) IPR003593 (13%) IPR025943 (13%)" "RNA polymerase sigma factor 54 interaction domain (13%) AAA+ ATPase domain (13%) Sigma-54 interaction domain, ATP-binding site 2 (13%)" QNLSWYTHYGLLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" CLLFDWDNDGDDALATGHGWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (26.7%) IPR014756 (26.7%) IPR040475 (26.7%)" "Immunoglobulin-like fold (26.7%) Immunoglobulin E-set (26.7%) Surface glycan-binding protein B, xyloglucan binding domain (26.7%)" LLAEEVSR root "2.7.7.7 (48.9%) 2.7.13.3 (11.1%) 1.-.-.- (8.9%)" "DNA-directed DNA polymerase (48.9%) histidine kinase (11.1%) Oxidoreductases (8.9%)" "GO:0034605 (8%) GO:0042026 (8%) GO:0006260 (4.8%)" "GO:0005737 (12.8%) GO:0005634 (1.7%) GO:0016020 (1.4%)" "GO:0005524 (9.7%) GO:0016887 (8%) GO:0003887 (4.8%)" "cellular response to heat (8%) protein refolding (8%) DNA replication (4.8%)" "cytoplasm (12.8%) nucleus (1.7%) membrane (1.4%)" "ATP binding (9.7%) ATP hydrolysis activity (8%) DNA-directed DNA polymerase activity (4.8%)" "IPR027417 (4.1%) IPR003593 (3.9%) IPR003959 (3.6%)" "P-loop containing nucleoside triphosphate hydrolase (4.1%) AAA+ ATPase domain (3.9%) ATPase, AAA-type, core (3.6%)" QLALLPYVTDLMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003735 (25%) GO:0070181 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "structural constituent of ribosome (25%) small ribosomal subunit rRNA binding (25%)" "IPR001648 (37.5%) IPR036870 (37.5%) IPR018275 (25%)" "Small ribosomal subunit protein bS18 (37.5%) Small ribosomal subunit protein bS18 superfamily (37.5%) Small ribosomal subunit protein bS18, conserved site (25%)" VTVNLASGDAVALNTVGETTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" LNADLVVATDPDADRLALVCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25.2%) GO:0006166 (25.2%)" "GO:0008973 (25.2%) GO:0000287 (24.3%)" "carbohydrate metabolic process (25.2%) purine ribonucleoside salvage (25.2%)" "phosphopentomutase activity (25.2%) magnesium ion binding (24.3%)" "IPR005846 (14.9%) IPR005844 (14.4%) IPR005845 (14.4%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.4%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.4%)" YVGVWWEMLSGK Bacteria Bacteria "3.2.1.22 (60%) 3.2.1.20 (20%) 3.2.1.3 (20%)" "alpha-galactosidase (60%) alpha-glucosidase (20%) glucan 1,4-alpha-glucosidase (20%)" "GO:0030246 (53.8%) GO:0016787 (42%) GO:0004557 (1.7%)" "carbohydrate binding (53.8%) hydrolase activity (42%) alpha-galactosidase activity (1.7%)" "IPR019563 (14.5%) IPR029486 (14.5%) IPR052720 (14.5%)" "Glycosyl-hydrolase 97, catalytic domain (14.5%) Glycosyl-hydrolase 97, N-terminal domain (14.5%) Glycosyl Hydrolase Family 97 (14.5%)" TPGYAEVLVGTPLSSFVANQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.2%) IPR022615 (20.2%) IPR056147 (20.2%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.2%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.2%) NqrA, N-terminal barrel-sandwich hybrid domain (20.2%)" DADFSWK root "3.4.-.- (61.1%) 6.1.1.10 (34.7%) 3.4.13.- (2.1%)" "Acting on peptide bonds (peptidases) (61.1%) methionine--tRNA ligase (34.7%) Dipeptidases (2.1%)" "GO:0006508 (16.6%) GO:0006431 (7.7%) GO:0003341 (0.3%)" "GO:0005829 (8%) GO:0005886 (0.9%) GO:0005634 (0.6%)" "GO:0016805 (16.6%) GO:0070004 (16.6%) GO:0005524 (8%)" "proteolysis (16.6%) methionyl-tRNA aminoacylation (7.7%) cilium movement (0.3%)" "cytosol (8%) plasma membrane (0.9%) nucleus (0.6%)" "dipeptidase activity (16.6%) cysteine-type exopeptidase activity (16.6%) ATP binding (8%)" "IPR005322 (17.1%) IPR009080 (7.9%) IPR014729 (7.9%)" "Peptidase C69 (17.1%) Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (7.9%) Rossmann-like alpha/beta/alpha sandwich fold (7.9%)" LGLAGGPLVMGLLLGALGPR Bacteria Bacteria GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.5%) IPR006512 (25.5%) IPR050144 (25.5%)" "Regulator of K+ conductance, C-terminal (25.5%) YidE/YbjL duplication (25.5%) AAE Transporter (25.5%)" LLTLLPEDYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013785 (50%) IPR036206 (50%)" "Aldolase-type TIM barrel (50%) Thiamin phosphate synthase superfamily (50%)" GLVGVTMPGFGTTDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.1 (92.9%) 6.3.1.5 (7.1%)" "NAD(+) synthase (glutamine-hydrolyzing) (92.9%) NAD(+) synthase (7.1%)" GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.5%) IPR003694 (14.5%) IPR014445 (14.5%)" "Carbon-nitrogen hydrolase (14.5%) NAD(+) synthetase (14.5%) Glutamine-dependent NAD(+) synthetase (14.5%)" GLSQNLFAGQYHSAFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR002881 (40.2%) IPR036465 (39.4%) IPR002035 (20.5%)" "Domain of unknown function DUF58 (40.2%) von Willebrand factor A-like domain superfamily (39.4%) von Willebrand factor, type A (20.5%)" FLQLAANVSEDHPVVVSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (94.1%) 6.3.4.16 (5.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (94.1%) carbamoyl-phosphate synthase (ammonia) (5.9%)" "GO:0006541 (13.6%) GO:0006526 (13%) GO:0006221 (12.8%)" GO:0005737 (13.6%) "GO:0004088 (13.6%) GO:0005524 (13.6%) GO:0046872 (13.6%)" "glutamine metabolic process (13.6%) L-arginine biosynthetic process (13%) pyrimidine nucleotide biosynthetic process (12.8%)" cytoplasm (13.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.6%) ATP binding (13.6%) metal ion binding (13.6%)" "IPR005479 (10.3%) IPR011761 (10.3%) IPR005480 (10%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.3%) ATP-grasp fold (10.3%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%)" EALDFFR root "1.1.1.1 (59.9%) 4.2.3.4 (24.3%) 2.4.1.18 (6.1%)" "alcohol dehydrogenase (59.9%) 3-dehydroquinate synthase (24.3%) 1,4-alpha-glucan branching enzyme (6.1%)" "GO:0008652 (2.9%) GO:0009073 (2.9%) GO:0009423 (2.9%)" "GO:0005737 (15.1%) GO:0009380 (2.4%) GO:0005829 (0.9%)" "GO:0008270 (11.4%) GO:0004022 (8%) GO:0046872 (4.2%)" "amino acid biosynthetic process (2.9%) aromatic amino acid family biosynthetic process (2.9%) chorismate biosynthetic process (2.9%)" "cytoplasm (15.1%) excinuclease repair complex (2.4%) cytosol (0.9%)" "zinc ion binding (11.4%) alcohol dehydrogenase (NAD+) activity (8%) metal ion binding (4.2%)" "IPR036291 (6.3%) IPR013149 (6.2%) IPR013154 (5.9%)" "NAD(P)-binding domain superfamily (6.3%) Alcohol dehydrogenase-like, C-terminal (6.2%) Alcohol dehydrogenase-like, N-terminal (5.9%)" TLLYFDMK root GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR013189 (11.4%) IPR001362 (10.7%) IPR013148 (10.7%)" "Glycosyl hydrolase family 32, C-terminal (11.4%) Glycoside hydrolase, family 32 (10.7%) Glycosyl hydrolase family 32, N-terminal (10.7%)" ADLNSLQTEVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SLGFDGLLNFYAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (51.9%) IPR035994 (48.1%)" "Nucleoside phosphorylase domain (51.9%) Nucleoside phosphorylase superfamily (48.1%)" LLDAALSR root "2.7.4.25 (31.7%) 2.2.1.6 (4.9%) 2.3.2.27 (4.9%)" "(d)CMP kinase (31.7%) acetolactate synthase (4.9%) RING-type E3 ubiquitin transferase (4.9%)" "GO:0006355 (2.2%) GO:0006220 (1.6%) GO:0001510 (0.9%)" "GO:0005886 (12.9%) GO:0005829 (3.7%) GO:0005737 (3%)" "GO:0042910 (11.2%) GO:0003677 (6.1%) GO:0003700 (4.3%)" "regulation of DNA-templated transcription (2.2%) pyrimidine nucleotide metabolic process (1.6%) RNA methylation (0.9%)" "plasma membrane (12.9%) cytosol (3.7%) cytoplasm (3%)" "xenobiotic transmembrane transporter activity (11.2%) DNA binding (6.1%) DNA-binding transcription factor activity (4.3%)" "IPR001036 (7.4%) IPR027463 (7.3%) IPR036388 (3.1%)" "Acriflavin resistance protein (7.4%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (7.3%) Winged helix-like DNA-binding domain superfamily (3.1%)" LSTFLDLYLQR Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (31.7%) GO:0005829 (34%) "GO:0008861 (34%) GO:0016829 (0.2%)" glucose metabolic process (31.7%) cytosol (34%) "formate C-acetyltransferase activity (34%) lyase activity (0.2%)" "IPR004184 (20.7%) IPR050244 (20.7%) IPR001150 (19.7%)" "Pyruvate formate lyase domain (20.7%) Autonomous Glycyl Radical Cofactor (20.7%) Glycine radical domain (19.7%)" NDLNSKDSELAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.6%) "GO:0009279 (26.3%) GO:0046930 (24.6%)" GO:0015288 (24.6%) monoatomic ion transport (24.6%) "cell outer membrane (26.3%) pore complex (24.6%)" porin activity (24.6%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" NNLVSLLNLLELMPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.1.3.2 (100%) UDP-glucose 4-epimerase (100%) "GO:0006012 (33%) GO:0005996 (0.4%)" GO:0005829 (33.2%) "GO:0003978 (33.2%) GO:0016853 (0.2%)" "galactose metabolic process (33%) monosaccharide metabolic process (0.4%)" cytosol (33.2%) "UDP-glucose 4-epimerase activity (33.2%) isomerase activity (0.2%)" "IPR036291 (33.3%) IPR005886 (33.1%) IPR001509 (19%)" "NAD(P)-binding domain superfamily (33.3%) UDP-glucose 4-epimerase (33.1%) NAD-dependent epimerase/dehydratase (19%)" LGEDWDNWDGGSDAEAATRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FQELQTPFYYYDTNVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.8%) "GO:0008836 (33.8%) GO:0030170 (32.4%)" lysine biosynthetic process via diaminopimelate (33.8%) "diaminopimelate decarboxylase activity (33.8%) pyridoxal phosphate binding (32.4%)" "IPR002986 (14.5%) IPR022643 (14.5%) IPR022644 (14.5%)" "Diaminopimelate decarboxylase, LysA (14.5%) Orn/DAP/Arg decarboxylase 2, C-terminal (14.5%) Orn/DAP/Arg decarboxylase 2, N-terminal (14.5%)" LDQSTTLTALAAFQEFLDLYPDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (34.4%) IPR039565 (34.4%) IPR011990 (31.3%)" "Outer membrane protein assembly factor BamD (34.4%) Outer membrane lipoprotein BamD-like (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" SDDLKGLSATDAGAALQGK Pseudomonadati Bacteria Pseudomonadati GO:0044718 (6.7%) GO:0009279 (86.7%) GO:0015344 (6.7%) siderophore transmembrane transport (6.7%) cell outer membrane (86.7%) siderophore uptake transmembrane transporter activity (6.7%) "IPR012910 (14.6%) IPR037066 (14.6%) IPR039426 (14.6%)" "TonB-dependent receptor, plug domain (14.6%) TonB-dependent receptor, plug domain superfamily (14.6%) TonB-dependent receptor-like (14.6%)" GEVVWTVDPASVLFFGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.2%) IPR022615 (20.2%) IPR056147 (20.2%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.2%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.2%) NqrA, N-terminal barrel-sandwich hybrid domain (20.2%)" LTGLDEPVLR Pseudomonadati Bacteria Pseudomonadati GO:0005886 (0.6%) "GO:0005524 (65.2%) GO:0016740 (32.3%) GO:0016301 (1.2%)" plasma membrane (0.6%) "ATP binding (65.2%) transferase activity (32.3%) kinase activity (1.2%)" "IPR005337 (25.4%) IPR053931 (25.4%) IPR002575 (24.7%)" "RapZ-like family (25.4%) RapZ, C-terminal domain (25.4%) Aminoglycoside phosphotransferase (24.7%)" FNVSNLLAVYGAALMLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.3%) GO:0009252 (12.3%) GO:0051301 (12.3%)" GO:0005737 (12.3%) "GO:0005524 (13%) GO:0000287 (12.3%) GO:0008765 (12.3%)" "regulation of cell shape (12.3%) peptidoglycan biosynthetic process (12.3%) cell division (12.3%)" cytoplasm (12.3%) "ATP binding (13%) magnesium ion binding (12.3%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.3%)" "IPR013221 (14.9%) IPR004101 (14.5%) IPR036565 (14.5%)" "Mur ligase, central (14.9%) Mur ligase, C-terminal (14.5%) Mur-like, catalytic domain superfamily (14.5%)" QLCSFYR root 2.7.7.49 (100%) RNA-directed DNA polymerase (100%) "GO:0044718 (20%) GO:0046854 (2.4%) GO:0070987 (2.4%)" "GO:0009279 (20%) GO:0016020 (3.8%) GO:0005634 (2.9%)" "GO:0015344 (20%) GO:0003677 (3.3%) GO:0004222 (1.4%)" "siderophore transmembrane transport (20%) phosphatidylinositol phosphate biosynthetic process (2.4%) error-free translesion synthesis (2.4%)" "cell outer membrane (20%) membrane (3.8%) nucleus (2.9%)" "siderophore uptake transmembrane transporter activity (20%) DNA binding (3.3%) metalloendopeptidase activity (1.4%)" "IPR000531 (13.9%) IPR012910 (13.9%) IPR039426 (13.9%)" "TonB-dependent receptor-like, beta-barrel (13.9%) TonB-dependent receptor, plug domain (13.9%) TonB-dependent receptor-like (13.9%)" WHNVDLNQQNREPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (26.1%) GO:0009341 (26.1%) "GO:0004565 (26.1%) GO:0030246 (21.6%)" lactose catabolic process (26.1%) beta-galactosidase complex (26.1%) "beta-galactosidase activity (26.1%) carbohydrate binding (21.6%)" "IPR050347 (8.7%) IPR004199 (8%) IPR006102 (8%)" "Bacterial Beta-galactosidase (8.7%) Beta galactosidase small chain/ domain 5 (8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8%)" LYEGEAVALLGNHPTLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) GO:0006281 (25%) GO:0005829 (25%) "GO:0008967 (25%) GO:2001070 (25%)" DNA repair (25%) cytosol (25%) "phosphoglycolate phosphatase activity (25%) starch binding (25%)" "IPR002044 (10.3%) IPR006439 (10.3%) IPR006549 (10.3%)" "Carbohydrate binding module family 20 (10.3%) HAD hydrolase, subfamily IA (10.3%) HAD-superfamily hydrolase,subfamily IIIA (10.3%)" AGVNASFLSEAGNDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0016301 (100%) kinase activity (100%) "IPR011611 (26%) IPR002173 (24.7%) IPR029056 (24.7%)" "Carbohydrate kinase PfkB (26%) Carbohydrate/purine kinase, PfkB, conserved site (24.7%) Ribokinase-like (24.7%)" FTCESKPEVTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.80 (100%) fructan beta-fructosidase (100%) GO:0005987 (33%) GO:0005737 (33%) "GO:0004575 (33%) GO:0051669 (1%)" sucrose catabolic process (33%) cytoplasm (33%) "sucrose alpha-glucosidase activity (33%) fructan beta-fructosidase activity (1%)" "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" EYEQGVTGLQLAESLSPALAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.3 (100%) threonine--tRNA ligase (100%) "GO:0006435 (16.4%) GO:0006412 (0.3%)" GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0005524 (16.7%) GO:0046872 (16.7%)" "threonyl-tRNA aminoacylation (16.4%) translation (0.3%)" cytoplasm (16.7%) "tRNA binding (16.7%) ATP binding (16.7%) metal ion binding (16.7%)" "IPR004095 (7.8%) IPR002314 (7.7%) IPR002320 (7.7%)" "TGS (7.8%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%)" MLVADTDLGCELRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (51.1%) IPR029052 (48.9%)" "Fructose-1,6-bisphosphatase class 3 (51.1%) Metallo-dependent phosphatase-like (48.9%)" HNYSMADAEVCFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR010870 (51.9%) IPR023614 (48.1%)" "Phosphate-selective porin O/P (51.9%) Porin domain superfamily (48.1%)" KTDQNVPMQLTAVWGCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036777 (100%) Nucleoside-specific channel-forming protein, Tsx-like superfamily (100%) NFKPMAAVGVGGYASGPTLNVCASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.8%) GO:0030259 (12.8%) GO:0008360 (12.2%)" GO:0005886 (12.2%) "GO:0050511 (12.2%) GO:0016758 (0.6%) GO:0051991 (0.6%)" "carbohydrate metabolic process (12.8%) obsolete lipid glycosylation (12.8%) regulation of cell shape (12.2%)" plasma membrane (12.2%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.2%) hexosyltransferase activity (0.6%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (0.6%)" "IPR004276 (34.5%) IPR006009 (32.8%) IPR007235 (32.8%)" "Glycosyltransferase family 28, N-terminal domain (34.5%) N-acetylglucosaminyltransferase, MurG (32.8%) Glycosyl transferase, family 28, C-terminal (32.8%)" ANFEPVDNNPYLADYYKDMER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) "GO:0005737 (30%) GO:0005739 (3.3%)" "GO:0005524 (33.3%) GO:0019136 (33.3%)" "cytoplasm (30%) mitochondrion (3.3%)" "ATP binding (33.3%) deoxynucleoside kinase activity (33.3%)" "IPR002624 (25%) IPR027417 (25%) IPR031314 (25%)" "Deoxynucleoside kinase (25%) P-loop containing nucleoside triphosphate hydrolase (25%) Deoxynucleoside kinase domain (25%)" LSPLLWR root "5.6.2.1 (96.7%) 2.4.99.12 (1.2%) 5.99.1.2 (0.6%)" "DNA topoisomerase (96.7%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (1.2%) Transferred entry: 5.6.2.1 (0.6%)" "GO:0006265 (14.6%) GO:0015833 (4.8%) GO:0045892 (4.7%)" "GO:0005694 (9.9%) GO:0016020 (1.5%) GO:0005737 (0.8%)" "GO:0003677 (19.6%) GO:0003917 (14.6%) GO:0008270 (10%)" "DNA topological change (14.6%) peptide transport (4.8%) negative regulation of DNA-templated transcription (4.7%)" "chromosome (9.9%) membrane (1.5%) cytoplasm (0.8%)" "DNA binding (19.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (14.6%) zinc ion binding (10%)" "IPR003601 (6%) IPR013497 (6%) IPR000380 (6%)" "DNA topoisomerase, type IA, domain 2 (6%) DNA topoisomerase, type IA, central (6%) DNA topoisomerase, type IA (6%)" ALFSDDLK root "2.5.1.6 (33.3%) 6.1.1.1 (33.3%) 6.2.1.30 (33.3%)" "methionine adenosyltransferase (33.3%) tyrosine--tRNA ligase (33.3%) phenylacetate--CoA ligase (33.3%)" "GO:0000070 (1.4%) GO:0006437 (1.4%) GO:0006556 (1.4%)" "GO:0016020 (5.6%) GO:0000444 (1.4%) GO:0005634 (1.4%)" "GO:0016788 (48.6%) GO:0005524 (4.2%) GO:0016787 (2.8%)" "mitotic sister chromatid segregation (1.4%) tyrosyl-tRNA aminoacylation (1.4%) S-adenosylmethionine biosynthetic process (1.4%)" "membrane (5.6%) MIS12/MIND type complex (1.4%) nucleus (1.4%)" "hydrolase activity, acting on ester bonds (48.6%) ATP binding (4.2%) hydrolase activity (2.8%)" "IPR013830 (20.4%) IPR053140 (20.4%) IPR036514 (19.3%)" "SGNH hydrolase-type esterase domain (20.4%) GDSL lipase Rv0518-like (20.4%) SGNH hydrolase superfamily (19.3%)" TVTVAYTLVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR013783 (34.1%) IPR014756 (34.1%) IPR002909 (31.8%)" "Immunoglobulin-like fold (34.1%) Immunoglobulin E-set (34.1%) IPT domain (31.8%)" YTVGYGATECAPLLCYEDYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.7%) IPR020845 (25.7%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.7%) ANL, N-terminal domain (24.3%)" ELAATCNEHGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0008233 (50%) proteolysis (50%) peptidase activity (50%) "IPR051454 (50%) IPR001539 (48.3%) IPR036237 (1.7%)" "RNA and ubiquinone modification enzymes (50%) Peptidase U32 (48.3%) Xylose isomerase-like superfamily (1.7%)" KLYPLGLQTFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.8%) IPR012547 (35.8%) IPR027417 (25.4%)" "AAA-ATPase-like domain (38.8%) PD-(D/E)XK nuclease superfamily 9 (35.8%) P-loop containing nucleoside triphosphate hydrolase (25.4%)" ASLQYLNLFLQEVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.7%) IPR011990 (32.7%) IPR012944 (32.7%)" "SusD-like, N-terminal (34.7%) Tetratricopeptide-like helical domain superfamily (32.7%) RagB/SusD domain (32.7%)" VAAEFNLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.9%) IPR006102 (7.9%) IPR006103 (7.9%)" "Beta galactosidase small chain/ domain 5 (7.9%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.9%) Glycoside hydrolase family 2, catalytic domain (7.9%)" NDQVLVDLK root 4.3.2.1 (100%) argininosuccinate lyase (100%) "GO:0042450 (33.1%) GO:0006526 (0.1%)" "GO:0005829 (33%) GO:0016020 (0.5%)" "GO:0004056 (33.1%) GO:0016829 (0.1%) GO:0015171 (0.1%)" "L-arginine biosynthetic process via ornithine (33.1%) L-arginine biosynthetic process (0.1%)" "cytosol (33%) membrane (0.5%)" "argininosuccinate lyase activity (33.1%) lyase activity (0.1%) amino acid transmembrane transporter activity (0.1%)" "IPR009049 (16.7%) IPR022761 (16.7%) IPR020557 (16.7%)" "Argininosuccinate lyase (16.7%) Fumarate lyase, N-terminal (16.7%) Fumarate lyase, conserved site (16.7%)" LDLHRPYVDK Bacteria Bacteria 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.5%) GO:0005737 (14.5%) "GO:0004822 (14.5%) GO:0005524 (14.5%) GO:0000049 (14.1%)" isoleucyl-tRNA aminoacylation (14.5%) cytoplasm (14.5%) "isoleucine-tRNA ligase activity (14.5%) ATP binding (14.5%) tRNA binding (14.1%)" "IPR002300 (12.9%) IPR002301 (12.9%) IPR023586 (12.9%)" "Aminoacyl-tRNA synthetase, class Ia (12.9%) Isoleucine-tRNA ligase (12.9%) Isoleucine-tRNA ligase, type 2 (12.9%)" LNTEVYGGPLMSTWFDRPLTLAGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.3%) GO:0005737 (19.5%) "GO:0004177 (20.3%) GO:0008270 (20.3%) GO:0008237 (19.5%)" proteolysis (20.3%) cytoplasm (19.5%) "aminopeptidase activity (20.3%) zinc ion binding (20.3%) metallopeptidase activity (19.5%)" "IPR001948 (51%) IPR023358 (49%)" "Peptidase M18 (51%) Peptidase M18, domain 2 (49%)" AAFQYMCDTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006355 (52.9%) GO:0006351 (47.1%)" "regulation of DNA-templated transcription (52.9%) DNA-templated transcription (47.1%)" "IPR013321 (52.9%) IPR007337 (47.1%)" "Arc-type ribbon-helix-helix (52.9%) RelB antitoxin/Antitoxin DinJ (47.1%)" FLVEMQNAFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) NVTMNLYNLMQGGLTLGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" LVELTANQMHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025632 (100%) Protein of unknown function DUF4290 (100%) LLANLTSK root "2.4.99.28 (41%) 6.1.1.20 (38.5%) 2.3.1.- (2.6%)" "peptidoglycan glycosyltransferase (41%) phenylalanine--tRNA ligase (38.5%) Transferring groups other than amino-acyl groups (2.6%)" "GO:0007059 (9.9%) GO:0007018 (2.4%) GO:0051231 (2.3%)" "GO:0005694 (9.9%) GO:0005737 (3.5%) GO:0005886 (3.4%)" "GO:0003677 (10.1%) GO:0005524 (5.4%) GO:0008017 (2.4%)" "chromosome segregation (9.9%) microtubule-based movement (2.4%) spindle elongation (2.3%)" "chromosome (9.9%) cytoplasm (3.5%) plasma membrane (3.4%)" "DNA binding (10.1%) ATP binding (5.4%) microtubule binding (2.4%)" "IPR041468 (8.1%) IPR050336 (8.1%) IPR003115 (8%)" "ParB/Spo0J, HTH domain (8.1%) Chromosome-partitioning and nucleoid occlusion protein (8.1%) ParB-like, N-terminal domain (8%)" NGTTVNLDGQLSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" NVDDFLK root "1.1.1.23 (51.3%) 6.1.1.16 (30.3%) 2.7.1.6 (3.2%)" "histidinol dehydrogenase (51.3%) cysteine--tRNA ligase (30.3%) galactokinase (3.2%)" "GO:0000105 (5.4%) GO:0006423 (4.1%) GO:0006508 (2%)" "GO:0005829 (12.3%) GO:0005737 (1.9%) GO:0016020 (1.6%)" "GO:0008270 (11.2%) GO:0005524 (5.5%) GO:0051287 (5.4%)" "L-histidine biosynthetic process (5.4%) cysteinyl-tRNA aminoacylation (4.1%) proteolysis (2%)" "cytosol (12.3%) cytoplasm (1.9%) membrane (1.6%)" "zinc ion binding (11.2%) ATP binding (5.5%) NAD binding (5.4%)" "IPR016161 (4.3%) IPR012131 (4.3%) IPR022695 (4.2%)" "Aldehyde/histidinol dehydrogenase (4.3%) Histidinol dehydrogenase (4.3%) Histidinol dehydrogenase, monofunctional (4.2%)" AMQESYDEDVTDEFLKPLNNSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" NFDTLEVTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.5%) IPR050220 (20.5%) IPR013757 (19.6%)" "DNA topoisomerase, type IIA, domain A (20.5%) Type II DNA Topoisomerases (20.5%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.6%)" GAASALYGANAVAGVVNLLSR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (17.1%) IPR012910 (17.1%) IPR039426 (17.1%)" "TonB-dependent receptor-like, beta-barrel (17.1%) TonB-dependent receptor, plug domain (17.1%) TonB-dependent receptor-like (17.1%)" ALLYNGEEFYESR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" LPQQLVNQSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) IPR017039 (100%) Virulence factor BrkB (100%) LFAYFFDDNGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" DGMDWDKLAELLFAGDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.15 (50%) 4.2.1.19 (50%)" "histidinol-phosphatase (50%) imidazoleglycerol-phosphate dehydratase (50%)" "GO:0000105 (20%) GO:0005975 (0.6%)" GO:0005737 (20%) "GO:0004401 (20%) GO:0004424 (20%) GO:0046872 (19.4%)" "L-histidine biosynthetic process (20%) carbohydrate metabolic process (0.6%)" cytoplasm (20%) "histidinol-phosphatase activity (20%) imidazoleglycerol-phosphate dehydratase activity (20%) metal ion binding (19.4%)" "IPR005954 (10.1%) IPR006543 (10.1%) IPR006549 (10.1%)" "Histidine biosynthesis bifunctional protein, N-terminal histidinol-phosphatase domain (10.1%) Histidinol-phosphate phosphatase (10.1%) HAD-superfamily hydrolase,subfamily IIIA (10.1%)" QFLQNNEDLDAFLEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (25%) GO:0031564 (23.4%) GO:0006355 (1.6%)" GO:0005829 (25%) GO:0003723 (25%) "DNA-templated transcription termination (25%) transcription antitermination (23.4%) regulation of DNA-templated transcription (1.6%)" cytosol (25%) RNA binding (25%) "IPR006027 (34%) IPR011605 (34%) IPR035926 (31.9%)" "NusB/RsmB/TIM44 (34%) NusB antitermination factor (34%) NusB-like superfamily (31.9%)" SVQPWSAESPYLYTLVLNTTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (6.7%) IPR006101 (6.7%) IPR006102 (6.7%)" "Beta galactosidase small chain/ domain 5 (6.7%) Glycoside hydrolase, family 2 (6.7%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.7%)" TGVDSLALSLGTSHGAYK root "4.1.2.13 (99.1%) 4.1.2.- (0.9%)" "fructose-bisphosphate aldolase (99.1%) Aldehyde-lyases (0.9%)" "GO:0006096 (23.7%) GO:0030388 (20.4%) GO:0005975 (2.8%)" "GO:0008270 (26.5%) GO:0004332 (20.9%) GO:0016832 (5.6%)" "glycolytic process (23.7%) fructose 1,6-bisphosphate metabolic process (20.4%) carbohydrate metabolic process (2.8%)" "zinc ion binding (26.5%) fructose-bisphosphate aldolase activity (20.9%) aldehyde-lyase activity (5.6%)" "IPR000771 (26.5%) IPR013785 (26.5%) IPR050246 (26.5%)" "Fructose-bisphosphate aldolase, class-II (26.5%) Aldolase-type TIM barrel (26.5%) Class II Fructose-bisphosphate Aldolase (26.5%)" ADSYPDSLSGGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25.3%) "GO:0005524 (25.3%) GO:0016887 (25.3%) GO:0015424 (24.2%)" plasma membrane (25.3%) "ATP binding (25.3%) ATP hydrolysis activity (25.3%) ABC-type amino acid transporter activity (24.2%)" "IPR003439 (16.9%) IPR003593 (16.9%) IPR017871 (16.9%)" "ABC transporter-like, ATP-binding domain (16.9%) AAA+ ATPase domain (16.9%) ABC transporter-like, conserved site (16.9%)" GTNSLTVLTDADAHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) GO:0022900 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0046872 (20%) GO:0051539 (20%)" electron transport chain (20%) plasma membrane (20%) "electron transfer activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR010208 (14.4%) IPR011538 (14.4%) IPR017896 (14.4%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.4%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" TSKEVLDYVDQNPGSLGVLGSNWLNDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" SKFSEEEAFSTPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LGDGEQVAFTPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (57.1%) "GO:0016787 (35.7%) GO:0016829 (7.1%)" carbohydrate metabolic process (57.1%) "hydrolase activity (35.7%) lyase activity (7.1%)" "IPR013783 (26.5%) IPR031965 (26.5%) IPR006047 (23.5%)" "Immunoglobulin-like fold (26.5%) Starch-binding module 26 (26.5%) Glycosyl hydrolase family 13, catalytic domain (23.5%)" LYNEYMELGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.2 (100%) pyruvate, water dikinase (100%) "GO:0005524 (49.6%) GO:0016301 (49.6%) GO:0008986 (0.8%)" "ATP binding (49.6%) kinase activity (49.6%) pyruvate, water dikinase activity (0.8%)" "IPR002192 (32.4%) IPR051549 (32.4%) IPR013815 (31.3%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (32.4%) Phosphoenolpyruvate Utilizing Enzyme (32.4%) ATP-grasp fold, subdomain 1 (31.3%)" NSDTTYGLGWLPLGGYCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (25.2%) GO:0016020 (25.2%) "GO:0004222 (25.2%) GO:0046872 (24.4%)" proteolysis (25.2%) membrane (25.2%) "metalloendopeptidase activity (25.2%) metal ion binding (24.4%)" "IPR004387 (24.4%) IPR008915 (24.4%) IPR041489 (23.7%)" "Peptidase M50, putative membrane-associated zinc metallopeptidase (24.4%) Peptidase M50 (24.4%) PDZ domain 6 (23.7%)" WTGSFSTNVYFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QDGSNTLESMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YNYSGYSALNTALDEALAALESAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" ALEQPELLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (20.2%) IPR051802 (20.2%) IPR001599 (19.4%)" "Macroglobulin domain (20.2%) Alpha-2-macroglobulin-like (20.2%) Alpha-2-macroglobulin (19.4%)" LFPLESPALDSLEVNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (33%) "GO:0022625 (33%) GO:0005840 (0.3%) GO:1990904 (0.3%)" GO:0003735 (33.3%) translation (33%) "cytosolic large ribosomal subunit (33%) ribosome (0.3%) ribonucleoprotein complex (0.3%)" structural constituent of ribosome (33.3%) "IPR001857 (25%) IPR008991 (25%) IPR018257 (25%)" "Large ribosomal subunit protein bL19 (25%) Translation protein SH3-like domain superfamily (25%) Large ribosomal subunit protein bL19, conserved site (25%)" ANGGVKDLTPASYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (3.8%) GO:0016020 (92.3%) GO:0008233 (3.8%) proteolysis (3.8%) membrane (92.3%) peptidase activity (3.8%) "IPR006665 (27.3%) IPR050330 (27.3%) IPR036737 (25%)" "OmpA-like domain (27.3%) Bacterial Outer Membrane Structural/Functional (27.3%) OmpA-like domain superfamily (25%)" SLGSVGRPLSCLQVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (34.1%) IPR020845 (34.1%) IPR042099 (31.9%)" "AMP-dependent synthetase/ligase domain (34.1%) AMP-binding, conserved site (34.1%) ANL, N-terminal domain (31.9%)" FVDSNEDNTLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) NPALQELQTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.4%) "GO:0004553 (34.4%) GO:0030246 (31.3%)" carbohydrate metabolic process (34.4%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.4%) carbohydrate binding (31.3%)" "IPR000322 (12.9%) IPR048395 (12.9%) IPR051816 (12.9%)" "Glycoside hydrolase family 31, TIM barrel domain (12.9%) Glycosyl hydrolase family 31, C-terminal domain (12.9%) Glycosyl Hydrolase Family 31 (12.9%)" LQEFASYNDSLEEVFENR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006351 (25%) GO:0000428 (25%) "GO:0003677 (25%) GO:0003899 (25%)" DNA-templated transcription (25%) DNA-directed RNA polymerase complex (25%) "DNA binding (25%) DNA-directed RNA polymerase activity (25%)" IPR006110 (100%) RNA polymerase, subunit omega/Rpo6/RPB6 (100%) LDQENSNYYSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" NNPLFYYLNFASASATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" EVPGLEVNMPQGAFYLFPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.- (100%) Transaminases (100%) GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004838 (16.7%) IPR004839 (16.7%) IPR015421 (16.7%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.7%) Aminotransferase, class I/classII, large domain (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" TVEGPDDYASMQEVVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006289 (16.7%) GO:0009432 (16.7%)" "GO:0005737 (16.7%) GO:0009380 (16.7%)" "GO:0003677 (16.7%) GO:0009381 (16.7%)" "nucleotide-excision repair (16.7%) SOS response (16.7%)" "cytoplasm (16.7%) excinuclease repair complex (16.7%)" "DNA binding (16.7%) excinuclease ABC activity (16.7%)" "IPR000305 (12.3%) IPR001162 (12.3%) IPR004791 (12.3%)" "GIY-YIG endonuclease (12.3%) UvrC, RNAse H endonuclease domain (12.3%) UvrABC system, subunit C (12.3%)" VSTEDLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR039426 (13.3%) IPR023996 (12.8%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent receptor-like (13.3%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" MTLAEFK root "1.17.99.9 (64.7%) 2.7.11.1 (5.9%) 2.7.7.85 (2.9%)" "heme a synthase (64.7%) non-specific serine/threonine protein kinase (5.9%) diadenylate cyclase (2.9%)" "GO:0006784 (13.4%) GO:0017004 (2.1%) GO:0016485 (1.7%)" "GO:0005743 (11.4%) GO:0005886 (4.2%) GO:0070069 (2.1%)" "GO:0046872 (15.3%) GO:0120547 (13.3%) GO:0016653 (12.4%)" "heme A biosynthetic process (13.4%) cytochrome complex assembly (2.1%) protein processing (1.7%)" "mitochondrial inner membrane (11.4%) plasma membrane (4.2%) cytochrome complex (2.1%)" "metal ion binding (15.3%) heme A synthase activity (13.3%) oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor (12.4%)" "IPR003780 (20%) IPR023754 (20%) IPR009003 (9.7%)" "COX15/CtaA family (20%) Heme A synthase, type 2 (20%) Peptidase S1, PA clan (9.7%)" LQALPGVVSTETLLSLEQSLKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0043200 (33.3%) GO:0005829 (33.3%) GO:0043565 (33.3%) response to amino acid (33.3%) cytosol (33.3%) sequence-specific DNA binding (33.3%) "IPR000485 (16.7%) IPR011008 (16.7%) IPR019887 (16.7%)" "AsnC-type HTH domain (16.7%) Dimeric alpha-beta barrel (16.7%) Transcription regulator AsnC/Lrp, ligand binding domain (16.7%)" FDMNQAPSYTDMHETLWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (34.8%) IPR011990 (30.4%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (30.4%)" EYNAFLAK root "2.1.1.14 (75%) 7.2.2.10 (8.3%) 7.2.2.3 (8.3%)" "5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (75%) P-type Ca(2+) transporter (8.3%) P-type Na(+) transporter (8.3%)" "GO:0032259 (8.9%) GO:0009086 (6.9%) GO:0015833 (2%)" "GO:0016020 (34.7%) GO:0005886 (3%) GO:0005737 (2%)" "GO:0003871 (6.9%) GO:0008270 (6.9%) GO:0008168 (2%)" "methylation (8.9%) methionine biosynthetic process (6.9%) peptide transport (2%)" "membrane (34.7%) plasma membrane (3%) cytoplasm (2%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (6.9%) zinc ion binding (6.9%) methyltransferase activity (2%)" "IPR003672 (32.7%) IPR002629 (8.2%) IPR006276 (8.2%)" "CobN/magnesium chelatase (32.7%) Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (8.2%) Cobalamin-independent methionine synthase (8.2%)" TAHAALMFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LLMNGLLK root "7.-.-.- (73.7%) 3.2.1.21 (10.5%) 2.3.2.27 (5.3%)" "Translocases (73.7%) beta-glucosidase (10.5%) RING-type E3 ubiquitin transferase (5.3%)" "GO:0006814 (23.3%) GO:0022900 (1.3%) GO:0006824 (1.2%)" "GO:0005886 (25.9%) GO:0016020 (1.6%) GO:0043190 (1.5%)" "GO:0015293 (23.3%) GO:0005524 (2%) GO:0016887 (1.8%)" "sodium ion transport (23.3%) electron transport chain (1.3%) cobalt ion transport (1.2%)" "plasma membrane (25.9%) membrane (1.6%) ATP-binding cassette (ABC) transporter complex (1.5%)" "symporter activity (23.3%) ATP binding (2%) ATP hydrolysis activity (1.8%)" "IPR001734 (22%) IPR038377 (22%) IPR051163 (22%)" "Sodium/solute symporter (22%) Sodium/glucose symporter superfamily (22%) Sodium:Solute Symporter (SSF) (22%)" TPPCADLLVR Bacteria Bacteria "3.5.4.26 (50.5%) 1.1.1.193 (49.5%)" "diaminohydroxyphosphoribosylaminopyrimidine deaminase (50.5%) 5-amino-6-(5-phosphoribosylamino)uracil reductase (49.5%)" GO:0009231 (25%) "GO:0008703 (25%) GO:0008835 (25%) GO:0046872 (20.8%)" riboflavin biosynthetic process (25%) "5-amino-6-(5-phosphoribosylamino)uracil reductase activity (25%) diaminohydroxyphosphoribosylaminopyrimidine deaminase activity (25%) metal ion binding (20.8%)" "IPR002125 (18%) IPR002734 (18%) IPR004794 (18%)" "Cytidine and deoxycytidylate deaminase domain (18%) Bacterial bifunctional deaminase-reductase, C-terminal (18%) Riboflavin biosynthesis protein RibD (18%)" FQQLDLKEPTEEEALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0034605 (24.7%) GO:0006508 (0.7%)" GO:0005737 (24.7%) "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0008233 (0.7%)" "cellular response to heat (24.7%) proteolysis (0.7%)" cytoplasm (24.7%) "ATP binding (24.7%) ATP hydrolysis activity (24.7%) peptidase activity (0.7%)" "IPR003593 (10.3%) IPR003959 (10.3%) IPR019489 (10.3%)" "AAA+ ATPase domain (10.3%) ATPase, AAA-type, core (10.3%) Clp ATPase, C-terminal (10.3%)" LQETLEGCALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (55.6%) IPR008160 (44.4%)" "Domain of unknown function DUF4988 (55.6%) Collagen triple helix repeat (44.4%)" HLVNLFGGLETTGLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LPMTEMSVDDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.69 (100%) gluconate 5-dehydrogenase (100%) "GO:0008874 (53.8%) GO:0016491 (46.2%)" "gluconate 5-dehydrogenase activity (53.8%) oxidoreductase activity (46.2%)" "IPR002347 (31%) IPR020904 (31%) IPR036291 (31%)" "Short-chain dehydrogenase/reductase SDR (31%) Short-chain dehydrogenase/reductase, conserved site (31%) NAD(P)-binding domain superfamily (31%)" VEAEKETETAAEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0015134 (50%) membrane (50%) hexuronate transmembrane transporter activity (50%) "IPR011701 (25.9%) IPR020846 (25.9%) IPR050382 (25.9%)" "Major facilitator superfamily (25.9%) Major facilitator superfamily domain (25.9%) Major Facilitator Superfamily Sodium/Anion Cotransporter (25.9%)" NKPVLTYPGEDLQEPYADFLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.21 (100%) starch synthase (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR013534 (100%) Starch synthase, catalytic domain (100%) FNLGANLDYYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" NALLQNFAPLTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (40%) IPR027417 (30%) IPR041682 (30%)" "Domain of unknown function DUF4143 (40%) P-loop containing nucleoside triphosphate hydrolase (30%) AAA domain, group 14 (30%)" GGVYTHLATLDPATSELTLVKNETTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008160 (50%) IPR032149 (50%)" "Collagen triple helix repeat (50%) Domain of unknown function DUF4988 (50%)" SYSHTFQLDASYPLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" WVNDWLVLGDDKDGDGCGDPVQQWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" ENQRFPEPLLTPTTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) "GO:0006189 (24.7%) GO:0039694 (0.6%)" GO:0005737 (24.7%) "GO:0004639 (24.7%) GO:0005524 (24.7%) GO:0003968 (0.6%)" "'de novo' IMP biosynthetic process (24.7%) viral RNA genome replication (0.6%)" cytoplasm (24.7%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (24.7%) ATP binding (24.7%) RNA-directed RNA polymerase activity (0.6%)" "IPR018236 (49.4%) IPR028923 (49.4%) IPR007094 (1.3%)" "SAICAR synthetase, conserved site (49.4%) SAICAR synthetase/ADE2, N-terminal (49.4%) RNA-directed RNA polymerase, catalytic domain (1.3%)" DLLADSVEYMVNAHK Pseudomonadati Bacteria Pseudomonadati 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.6%) GO:0009099 (16.6%) GO:0008652 (0%)" GO:0005829 (16.7%) "GO:0004160 (16.7%) GO:0051537 (16.6%) GO:0000287 (15.9%)" "isoleucine biosynthetic process (16.6%) L-valine biosynthetic process (16.6%) amino acid biosynthetic process (0%)" cytosol (16.7%) "dihydroxy-acid dehydratase activity (16.7%) 2 iron, 2 sulfur cluster binding (16.6%) magnesium ion binding (15.9%)" "IPR000581 (16.7%) IPR020558 (16.7%) IPR004404 (16.7%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.7%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.7%) Dihydroxy-acid dehydratase (16.7%)" YHPGSGNLSDLYVGCLCDLPLMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.7%) IPR012944 (32.1%) IPR033985 (32.1%)" "Tetratricopeptide-like helical domain superfamily (35.7%) RagB/SusD domain (32.1%) SusD-like, N-terminal (32.1%)" QLLEDEGLVCPLSGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (13%) GO:0015966 (12.2%)" "GO:0005737 (13%) GO:0070062 (12.2%) GO:1990742 (12.2%)" "GO:0004820 (13%) GO:0004081 (12.2%) GO:0005524 (12.2%)" "glycyl-tRNA aminoacylation (13%) diadenosine tetraphosphate biosynthetic process (12.2%)" "cytoplasm (13%) extracellular exosome (12.2%) microvesicle (12.2%)" "glycine-tRNA ligase activity (13%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.2%) ATP binding (12.2%)" "IPR027031 (11.9%) IPR002314 (11.1%) IPR002315 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.9%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Glycyl-tRNA synthetase (11.1%)" ETELTADNLEELVESGAQTVLLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.5%) IPR007644 (8.5%) IPR015712 (8.5%)" "RNA polymerase Rpb2, domain 2 (8.5%) RNA polymerase, beta subunit, protrusion (8.5%) DNA-directed RNA polymerase, subunit 2 (8.5%)" VALVTGAAYGLGFAMAEAYAK Bacteria Bacteria 1.1.1.69 (100%) gluconate 5-dehydrogenase (100%) GO:0008206 (40%) "GO:0008874 (40%) GO:0016616 (20%)" bile acid metabolic process (40%) "gluconate 5-dehydrogenase activity (40%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (20%)" "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" NAPLTDYSYDATGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) EQGYQGNLEYVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016020 (59.3%) "GO:0016740 (22.2%) GO:0016757 (18.5%)" membrane (59.3%) "transferase activity (22.2%) glycosyltransferase activity (18.5%)" "IPR029044 (51.6%) IPR050834 (48.4%)" "Nucleotide-diphospho-sugar transferases (51.6%) Glycosyltransferase 2 family enzymes (48.4%)" ALVNAGLPVHGHLGLTPQSVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.11 (100%) 3-methyl-2-oxobutanoate hydroxymethyltransferase (100%) "GO:0015940 (19.4%) GO:0032259 (11.3%)" GO:0005737 (19.4%) "GO:0000287 (19.4%) GO:0003864 (19.4%) GO:0008168 (11.3%)" "pantothenate biosynthetic process (19.4%) methylation (11.3%)" cytoplasm (19.4%) "magnesium ion binding (19.4%) 3-methyl-2-oxobutanoate hydroxymethyltransferase activity (19.4%) methyltransferase activity (11.3%)" "IPR003700 (33.3%) IPR015813 (33.3%) IPR040442 (33.3%)" "Ketopantoate hydroxymethyltransferase (33.3%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (33.3%) Pyruvate kinase-like domain superfamily (33.3%)" TMADKLAAELMDAFNNQGGAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (20%) GO:0015935 (20%) "GO:0000049 (20%) GO:0003735 (20%) GO:0019843 (20%)" translation (20%) small ribosomal subunit (20%) "tRNA binding (20%) structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" WFSDYFFEAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) NAWFPSLSLGWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" NMLLSGVNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.8%) GO:0006811 (3.2%)" GO:0009279 (50%) "iron ion transport (46.8%) monoatomic ion transport (3.2%)" cell outer membrane (50%) "IPR000531 (25.6%) IPR039426 (25.6%) IPR012910 (24.8%)" "TonB-dependent receptor-like, beta-barrel (25.6%) TonB-dependent receptor-like (25.6%) TonB-dependent receptor, plug domain (24.8%)" AFTLEDLNFGGNNYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" SAGSQLLTR Bacteria Bacteria "GO:0042777 (18.5%) GO:0008643 (0.3%) GO:0015074 (0.3%)" "GO:0045259 (19.3%) GO:0005886 (18.5%) GO:0055052 (0.3%)" "GO:0046933 (19.3%) GO:0005524 (19%) GO:0016787 (2.9%)" "proton motive force-driven plasma membrane ATP synthesis (18.5%) carbohydrate transport (0.3%) DNA integration (0.3%)" "proton-transporting ATP synthase complex (19.3%) plasma membrane (18.5%) ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing (0.3%)" "proton-transporting ATP synthase activity, rotational mechanism (19.3%) ATP binding (19%) hydrolase activity (2.9%)" "IPR000131 (44.2%) IPR035968 (42.9%) IPR027417 (1.2%)" "ATP synthase, F1 complex, gamma subunit (44.2%) ATP synthase, F1 complex, gamma subunit superfamily (42.9%) P-loop containing nucleoside triphosphate hydrolase (1.2%)" KTFGAAFATYELNDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" NVTHVSLWTR root "IPR029625 (45.7%) IPR024361 (26.1%) IPR012640 (17.4%)" "Protein FAM169 (45.7%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (26.1%) Membrane lipoprotein, lipid attachment site (17.4%)" SNADALAGQLGEVTEMLPAGGYGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) "IPR002810 (34.5%) IPR052165 (34.5%) IPR012340 (31%)" "NfeD-like, C-terminal domain (34.5%) Membrane-associated protease and related proteins (34.5%) Nucleic acid-binding, OB-fold (31%)" LLLEEHQYQAEQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004519 (100%) endonuclease activity (100%) NQGNYTLPAVEFTYYDTSANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR013105 (25.4%) IPR019734 (25.4%) IPR025738 (25.4%)" "Tetratricopeptide repeat 2 (25.4%) Tetratricopeptide repeat (25.4%) Aerotolerance-related protein BatD (25.4%)" VMTLDTFFQSVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.5%) GO:0005829 (16.5%) "GO:0003677 (16.5%) GO:0004527 (16.5%) GO:0005524 (16.5%)" recombinational repair (16.5%) cytosol (16.5%) "DNA binding (16.5%) exonuclease activity (16.5%) ATP binding (16.5%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" SNSNLSDLPVLLLTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (26.6%) GO:0003700 (26.6%) GO:0043565 (26.6%)" "phosphorelay sensor kinase activity (26.6%) DNA-binding transcription factor activity (26.6%) sequence-specific DNA binding (26.6%)" "IPR001789 (6.8%) IPR003594 (6.8%) IPR003661 (6.8%)" "Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%)" GTALTYPLSTNLYWQFLTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0042918 (27.8%) GO:0042597 (72.2%) alkanesulfonate transmembrane transport (27.8%) periplasmic space (72.2%) IPR015168 (100%) SsuA/THI5-like (100%) LDEKLEEALDWVSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.4%) IPR019998 (17.4%) IPR028053 (17.4%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.4%) Membrane insertase YidC (17.4%) Membrane insertase YidC, N-terminal (17.4%)" KQLNDGVALFSHLYDEWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella SHMGGGLEVAHLDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) TASLCVQGGYEPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (20%) IPR006235 (20%) IPR015421 (20%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (20%) O-acetylhomoserine/O-acetylserine sulfhydrylase (20%) Pyridoxal phosphate-dependent transferase, major domain (20%)" WAEVLDADAFSVFK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.4.-.- (43.8%) 3.4.15.5 (31.3%) 3.4.24.- (12.5%)" "Acting on peptide bonds (peptidases) (43.8%) peptidyl-dipeptidase Dcp (31.3%) Metalloendopeptidases (12.5%)" "GO:0006508 (19.7%) GO:0006355 (0.3%)" GO:0005829 (19.7%) "GO:0004180 (19.7%) GO:0004222 (19.7%) GO:0046872 (19.7%)" "proteolysis (19.7%) regulation of DNA-templated transcription (0.3%)" cytosol (19.7%) "carboxypeptidase activity (19.7%) metalloendopeptidase activity (19.7%) metal ion binding (19.7%)" "IPR001567 (18.9%) IPR045090 (18.9%) IPR034005 (18.8%)" "Peptidase M3A/M3B catalytic domain (18.9%) Peptidase M3A/M3B (18.9%) Peptidyl-dipeptidase DCP (18.8%)" QLMLMQSLCEAAGMVSPQLEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" GLLSNLDLGVGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR041700 (90.2%) IPR008969 (9.8%)" "Outer membrane protein beta-barrel domain 3 (90.2%) Carboxypeptidase-like, regulatory domain superfamily (9.8%)" GPGQNALTASGMEVVPSLYNLLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) VLSSNLLLNLNEPCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" SAVTFVVPEGAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (26.9%) IPR014756 (26.9%) IPR040475 (26.9%)" "Immunoglobulin-like fold (26.9%) Immunoglobulin E-set (26.9%) Surface glycan-binding protein B, xyloglucan binding domain (26.9%)" FNGWDRPLLTDSGGFQVFSLTGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.29 (100%) tRNA-guanosine(34) preQ1 transglycosylase (100%) GO:0002099 (33.3%) GO:0005829 (33.3%) "GO:0008479 (32.3%) GO:0016757 (1%)" tRNA wobble guanine modification (33.3%) cytosol (33.3%) "tRNA-guanosine(34) queuine transglycosylase activity (32.3%) glycosyltransferase activity (1%)" "IPR002616 (25.2%) IPR036511 (25.2%) IPR050076 (25.2%)" "tRNA-guanine(15) transglycosylase-like (25.2%) Queuine tRNA-ribosyltransferase-like (25.2%) Archaeosine Synthase Type 1/Queuine TRNA-Ribosyltransferase (25.2%)" TKVVDLLK root "6.1.1.22 (58%) 3.2.1.39 (14%) 3.5.1.18 (12%)" "asparagine--tRNA ligase (58%) glucan endo-1,3-beta-D-glucosidase (14%) succinyl-diaminopimelate desuccinylase (12%)" "GO:0006421 (7%) GO:0000271 (3.4%) GO:0005975 (2.3%)" "GO:0005737 (8.3%) GO:0005886 (3.4%) GO:0098552 (2.3%)" "GO:0005524 (7.8%) GO:0003676 (7%) GO:0004816 (7%)" "asparaginyl-tRNA aminoacylation (7%) polysaccharide biosynthetic process (3.4%) carbohydrate metabolic process (2.3%)" "cytoplasm (8.3%) plasma membrane (3.4%) side of membrane (2.3%)" "ATP binding (7.8%) nucleic acid binding (7%) asparagine-tRNA ligase activity (7%)" "IPR004364 (4.5%) IPR004365 (4.5%) IPR004522 (4.5%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (4.5%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (4.5%) Asparagine-tRNA ligase (4.5%)" GMGAPAADALVAER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006260 (33.3%) "GO:0003887 (33.3%) GO:0008408 (33.3%)" DNA replication (33.3%) "DNA-directed DNA polymerase activity (33.3%) 3'-5' exonuclease activity (33.3%)" "IPR003141 (12.6%) IPR004013 (12.6%) IPR004805 (12.6%)" "Polymerase/histidinol phosphatase, N-terminal (12.6%) PHP domain (12.6%) Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC (12.6%)" GEDGKWGGNSTWAGTVNPVAQSQDAGYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" GFDLNLFLQGVTGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" HLGLYAYR root "2.7.7.38 (99.9%) 2.7.7.90 (0.1%) 2.7.7.- (0%)" "3-deoxy-manno-octulosonate cytidylyltransferase (99.9%) 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase (0.1%) Nucleotidyltransferases (0%)" "GO:0009103 (20.7%) GO:0033468 (20%) GO:0044281 (0.3%)" "GO:0005829 (21.1%) GO:0016020 (16.2%) GO:0005737 (0%)" "GO:0008690 (21.2%) GO:0016779 (0.2%) GO:0005524 (0%)" "lipopolysaccharide biosynthetic process (20.7%) CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process (20%) small molecule metabolic process (0.3%)" "cytosol (21.1%) membrane (16.2%) cytoplasm (0%)" "3-deoxy-manno-octulosonate cytidylyltransferase activity (21.2%) nucleotidyltransferase activity (0.2%) ATP binding (0%)" "IPR003329 (33.4%) IPR029044 (33.3%) IPR004528 (33.1%)" "Acylneuraminate cytidylyltransferase (33.4%) Nucleotide-diphospho-sugar transferases (33.3%) 3-deoxy-D-manno-octulosonate cytidylyltransferase (33.1%)" LQDDACLAAVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0034605 (19.5%) GO:0042026 (18%) GO:0006508 (2%)" GO:0005737 (19.5%) "GO:0005524 (19.5%) GO:0016887 (19.5%) GO:0008233 (2%)" "cellular response to heat (19.5%) protein refolding (18%) proteolysis (2%)" cytoplasm (19.5%) "ATP binding (19.5%) ATP hydrolysis activity (19.5%) peptidase activity (2%)" "IPR018368 (8.7%) IPR041546 (8.7%) IPR050130 (8.7%)" "ClpA/B, conserved site 1 (8.7%) ClpA/ClpB, AAA lid domain (8.7%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.7%)" FWLELGSR root "3.1.4.- (50%) 7.2.2.8 (50%)" "Phosphoric diester hydrolases (50%) P-type Cu(+) transporter (50%)" "GO:0000972 (3.3%) GO:0006405 (3.3%) GO:0006606 (3.3%)" "GO:0009279 (30%) GO:0012505 (3.3%) GO:0016020 (3.3%)" "GO:0005524 (6.7%) GO:0004114 (3.3%) GO:0004672 (3.3%)" "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery (3.3%) RNA export from nucleus (3.3%) protein import into nucleus (3.3%)" "cell outer membrane (30%) endomembrane system (3.3%) membrane (3.3%)" "ATP binding (6.7%) 3',5'-cyclic-nucleotide phosphodiesterase activity (3.3%) protein kinase activity (3.3%)" "IPR011990 (16.9%) IPR012944 (15.3%) IPR033985 (15.3%)" "Tetratricopeptide-like helical domain superfamily (16.9%) RagB/SusD domain (15.3%) SusD-like, N-terminal (15.3%)" HPHFWAGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.2%) GO:0016787 (50.8%) carbohydrate metabolic process (49.2%) hydrolase activity (50.8%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" DLDDNGLVR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (19%) GO:0007156 (0.7%) GO:0009887 (0.7%)" "GO:0000428 (19%) GO:0005886 (0.7%) GO:0005911 (0.7%)" "GO:0003677 (19%) GO:0003899 (19%) GO:0032549 (19%)" "DNA-templated transcription (19%) homophilic cell-cell adhesion (0.7%) animal organ morphogenesis (0.7%)" "DNA-directed RNA polymerase complex (19%) plasma membrane (0.7%) cell-cell junction (0.7%)" "DNA binding (19%) DNA-directed RNA polymerase activity (19%) ribonucleoside binding (19%)" "IPR007120 (7.9%) IPR015712 (7.9%) IPR007121 (7.6%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) DNA-directed RNA polymerase, subunit 2 (7.9%) RNA polymerase, beta subunit, conserved site (7.6%)" KVEHMVNEMLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" HAFSDAFK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0032790 (25.2%) "GO:0005525 (25.2%) GO:0003746 (24.8%) GO:0003924 (24.8%)" ribosome disassembly (25.2%) "GTP binding (25.2%) translation elongation factor activity (24.8%) GTPase activity (24.8%)" "IPR000640 (7.8%) IPR005517 (7.8%) IPR035649 (7.8%)" "Elongation factor EFG, domain V-like (7.8%) Translation elongation factor EFG/EF2, domain IV (7.8%) EFG, domain V (7.8%)" NTAPCLAYACWK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (31.7%) "GO:0004475 (31.7%) GO:0005525 (31.4%) GO:0016853 (3.1%)" GDP-mannose biosynthetic process (31.7%) "mannose-1-phosphate guanylyltransferase (GTP) activity (31.7%) GTP binding (31.4%) isomerase activity (3.1%)" "IPR005835 (24.5%) IPR049577 (24.5%) IPR051161 (24.5%)" "Nucleotidyl transferase domain (24.5%) GDP-mannose pyrophosphorylase, N-terminal domain (24.5%) Mannose-6-phosphate isomerase type 2 (24.5%)" VKLTLQEAATGVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006260 (11.7%) GO:0009408 (11.7%) GO:0042026 (11.7%)" GO:0005737 (11.7%) "GO:0005524 (11.7%) GO:0008270 (11.7%) GO:0031072 (11.7%)" "DNA replication (11.7%) response to heat (11.7%) protein refolding (11.7%)" cytoplasm (11.7%) "ATP binding (11.7%) zinc ion binding (11.7%) heat shock protein binding (11.7%)" "IPR001305 (12.8%) IPR001623 (12.8%) IPR002939 (12.8%)" "Heat shock protein DnaJ, cysteine-rich domain (12.8%) DnaJ domain (12.8%) Chaperone DnaJ, C-terminal (12.8%)" YCQAYFSYDSKK Bacteria Bacteria "1.2.7.1 (85.2%) 1.2.7.- (11.1%) 1.2.1.51 (3.7%)" "pyruvate synthase (85.2%) With an iron-sulfur protein as acceptor (11.1%) pyruvate dehydrogenase (NADP(+)) (3.7%)" "GO:0006979 (15.1%) GO:0022900 (15%) GO:0044281 (11.2%)" "GO:0005506 (15%) GO:0051539 (15%) GO:0030976 (13.5%)" "response to oxidative stress (15.1%) electron transport chain (15%) small molecule metabolic process (11.2%)" "iron ion binding (15%) 4 iron, 4 sulfur cluster binding (15%) thiamine pyrophosphate binding (13.5%)" "IPR019752 (7.9%) IPR050722 (7.9%) IPR011895 (7.8%)" "Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (7.9%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.9%) Pyruvate-flavodoxin oxidoreductase (7.8%)" AWKPVVNELQNFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.193 (100%) 16S rRNA (uracil(1498)-N(3))-methyltransferase (100%) GO:0070475 (33.3%) GO:0005737 (33.3%) GO:0070042 (33.3%) rRNA base methylation (33.3%) cytoplasm (33.3%) rRNA (uridine-N3-)-methyltransferase activity (33.3%) "IPR006700 (17.5%) IPR046886 (17.5%) IPR046887 (17.5%)" "Ribosomal RNA small subunit methyltransferase E (17.5%) Ribosomal RNA small subunit methyltransferase E, methyltransferase domain (17.5%) Ribosomal RNA small subunit methyltransferase E, PUA-like domain (17.5%)" DPFDVLDELEAELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006449 (16.7%) GO:0005829 (16.7%) "GO:0003924 (16.7%) GO:0005525 (16.7%) GO:0016149 (16.7%)" regulation of translational termination (16.7%) cytosol (16.7%) "GTPase activity (16.7%) GTP binding (16.7%) translation release factor activity, codon specific (16.7%)" "IPR000795 (9.1%) IPR004548 (9.1%) IPR005225 (9.1%)" "Translational (tr)-type GTP-binding domain (9.1%) Peptide chain release factor 3 (9.1%) Small GTP-binding domain (9.1%)" SLFAEHFPSDSAAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.3%) IPR006426 (14.3%) IPR014729 (14.3%)" "Asparagine synthase (14.3%) Asparagine synthase, glutamine-hydrolyzing (14.3%) Rossmann-like alpha/beta/alpha sandwich fold (14.3%)" GVLVAESFDYELLDK Bacteria Bacteria "1.1.1.- (81.8%) 1.1.1.57 (18.2%)" "With NAD(+) or NADP(+) as acceptor (81.8%) fructuronate reductase (18.2%)" "GO:0016616 (93.4%) GO:0008926 (3.9%) GO:0008866 (2.6%)" "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (93.4%) mannitol-1-phosphate 5-dehydrogenase activity (3.9%) fructuronate reductase activity (2.6%)" "IPR013131 (17%) IPR050988 (17%) IPR013118 (16.8%)" "Mannitol dehydrogenase, N-terminal (17%) Mannitol Dehydrogenase/Oxidoreductase (17%) Mannitol dehydrogenase, C-terminal (16.8%)" FSALGTFSGALFGVDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (50%) GO:0016788 (47.1%) GO:0016787 (2.9%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (47.1%) hydrolase activity (2.9%)" "IPR000801 (17.2%) IPR005181 (17.2%) IPR050583 (17.2%)" "Esterase-like (17.2%) Sialate O-acetylesterase domain (17.2%) Mycobacterial A85 antigen (17.2%)" YNMPNNWAETMGADYSVKPAVGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" DYGNALTYLNMVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" KVAEDLTPDYPDLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.1.88 (100%) peptide deformylase (100%) "GO:0006412 (25%) GO:0043686 (25%)" "GO:0042586 (25%) GO:0046872 (25%)" "translation (25%) obsolete co-translational protein modification (25%)" "peptide deformylase activity (25%) metal ion binding (25%)" "IPR023635 (50%) IPR036821 (50%)" "Peptide deformylase (50%) Peptide deformylase superfamily (50%)" ELDVLDNKPLDCEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (13.1%) IPR031704 (13.1%) IPR031705 (13.1%)" "Glycoside hydrolase family 36 (13.1%) Glycosyl hydrolase family 36, N-terminal (13.1%) Glycosyl hydrolase family 36, C-terminal (13.1%)" HLTKEDGAMAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (25%) IPR012340 (25%) IPR035104 (25%)" "S1 domain (25%) Nucleic acid-binding, OB-fold (25%) Ribosomal protein S1-like (25%)" ELLGEGQRWEDLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" METLEQTLMQVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YTLGSVLNHVALHQTLLGLEAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (21.3%) IPR006316 (21.3%) IPR023026 (21.3%)" "Tryptophan synthase beta chain-like, PALP domain (21.3%) Tryptophan synthase, beta chain-like (21.3%) Tryptophan synthase beta chain/beta chain-like (21.3%)" EGALDMAWEYLTEVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.1%) IPR003156 (9.1%) IPR009000 (9.1%)" "Alanine-tRNA ligase, class IIc (9.1%) DHHA1 domain (9.1%) Translation protein, beta-barrel domain superfamily (9.1%)" NAYDWSK root 6.1.1.4 (100%) leucine--tRNA ligase (100%) "GO:0044718 (27.3%) GO:0006429 (2.3%)" "GO:0009279 (27.3%) GO:0005829 (2.3%) GO:0045211 (2.3%)" "GO:0015344 (27.3%) GO:0002161 (2.3%) GO:0004823 (2.3%)" "siderophore transmembrane transport (27.3%) leucyl-tRNA aminoacylation (2.3%)" "cell outer membrane (27.3%) cytosol (2.3%) postsynaptic membrane (2.3%)" "siderophore uptake transmembrane transporter activity (27.3%) aminoacyl-tRNA deacylase activity (2.3%) leucine-tRNA ligase activity (2.3%)" "IPR000531 (11.5%) IPR012910 (11.5%) IPR023996 (11.5%)" "TonB-dependent receptor-like, beta-barrel (11.5%) TonB-dependent receptor, plug domain (11.5%) TonB-dependent outer membrane protein, SusC/RagA (11.5%)" RMAQFELTLLDWAEAHK Bacteria Bacteria "GO:0006004 (32.2%) GO:0005996 (1.1%)" GO:0005737 (33.3%) "GO:0008736 (32.2%) GO:0016861 (1.1%)" "fucose metabolic process (32.2%) monosaccharide metabolic process (1.1%)" cytoplasm (33.3%) "L-fucose isomerase activity (32.2%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1.1%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" SWNEDFVDEDTGEVVSLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.2%) IPR015712 (8.2%) IPR007645 (8.2%)" "RNA polymerase Rpb2, domain 2 (8.2%) DNA-directed RNA polymerase, subunit 2 (8.2%) RNA polymerase Rpb2, domain 3 (8.2%)" NAANFAAYLNAGYDAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (45.7%) "GO:0015926 (45.7%) GO:0031218 (8.6%)" pectin catabolic process (45.7%) "glucosidase activity (45.7%) arabinogalactan endo-1,4-beta-galactosidase activity (8.6%)" "IPR011683 (53.3%) IPR017853 (46.7%)" "Glycosyl hydrolase family 53 (53.3%) Glycoside hydrolase superfamily (46.7%)" RSNHVTLFVDAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25.1%) GO:0022625 (25.1%) "GO:0003735 (25.1%) GO:0019843 (24.7%)" translation (25.1%) cytosolic large ribosomal subunit (25.1%) "structural constituent of ribosome (25.1%) rRNA binding (24.7%)" "IPR001063 (25.1%) IPR036394 (25.1%) IPR047867 (25.1%)" "Large ribosomal subunit protein uL22 (25.1%) Ribosomal protein uL22 superfamily (25.1%) Large ribosomal subunit protein uL22, bacteria/organella (25.1%)" LFVYLVTK Bacteria Bacteria "GO:0046677 (22.7%) GO:0006508 (0.8%) GO:0008360 (0.8%)" "GO:0005886 (22.7%) GO:0030313 (22.7%) GO:0016020 (5%)" "GO:0022857 (22.7%) GO:0009002 (0.8%)" "response to antibiotic (22.7%) proteolysis (0.8%) regulation of cell shape (0.8%)" "plasma membrane (22.7%) cell envelope (22.7%) membrane (5%)" "transmembrane transporter activity (22.7%) serine-type D-Ala-D-Ala carboxypeptidase activity (0.8%)" "IPR006143 (29.7%) IPR032317 (29.7%) IPR051160 (29.7%)" "RND efflux pump, membrane fusion protein (29.7%) Unknown (29.7%) Unknown (29.7%)" LNFDHPSAFDWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.7.1.48 (93.3%) 2.7.1.- (6.7%)" "uridine/cytidine kinase (93.3%) Phosphotransferases with an alcohol group as acceptor (6.7%)" "GO:0044206 (18.9%) GO:0044211 (18.9%)" GO:0005737 (18.9%) "GO:0005524 (20.3%) GO:0004849 (18.9%) GO:0043771 (2.7%)" "UMP salvage (18.9%) CTP salvage (18.9%)" cytoplasm (18.9%) "ATP binding (20.3%) uridine kinase activity (18.9%) cytidine kinase activity (2.7%)" "IPR006083 (25.9%) IPR027417 (25.9%) IPR000764 (24.1%)" "Phosphoribulokinase/uridine kinase (25.9%) P-loop containing nucleoside triphosphate hydrolase (25.9%) Uridine kinase-like (24.1%)" LEQDFFGR root "2.1.1.199 (86.7%) 2.1.1.- (13.3%)" "16S rRNA (cytosine(1402)-N(4))-methyltransferase (86.7%) Methyltransferases (13.3%)" "GO:0070475 (16.4%) GO:0032259 (13.7%) GO:0000266 (1.4%)" "GO:0005737 (16.4%) GO:0016020 (2.7%) GO:0005739 (1.4%)" "GO:0008757 (16.4%) GO:0071424 (16.4%) GO:0008168 (5.5%)" "rRNA base methylation (16.4%) methylation (13.7%) mitochondrial fission (1.4%)" "cytoplasm (16.4%) membrane (2.7%) mitochondrion (1.4%)" "S-adenosylmethionine-dependent methyltransferase activity (16.4%) rRNA (cytosine-N4-)-methyltransferase activity (16.4%) methyltransferase activity (5.5%)" "IPR029063 (41.1%) IPR002903 (17.8%) IPR013216 (16.4%)" "S-adenosyl-L-methionine-dependent methyltransferase superfamily (41.1%) Ribosomal RNA small subunit methyltransferase H (17.8%) Methyltransferase type 11 (16.4%)" DKNLQLGVVAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0042918 (25%) GO:0042597 (75%) alkanesulfonate transmembrane transport (25%) periplasmic space (75%) IPR015168 (100%) SsuA/THI5-like (100%) LEDGDLLFKPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EQPAAGCFEYREE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR011050 (33.3%) IPR012334 (33.3%) IPR039448 (33.3%)" "Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%) Right handed beta helix domain (33.3%)" NEAQGSDLNGVTGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (96.8%) GO:0016020 (3.2%)" "cell outer membrane (96.8%) membrane (3.2%)" "IPR011659 (15.1%) IPR006665 (14.2%) IPR011042 (14.2%)" "WD40-like beta-propeller (15.1%) OmpA-like domain (14.2%) Six-bladed beta-propeller, TolB-like (14.2%)" NAYDPQFNVDGVWDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" YVQDLYR root "2.3.1.- (50%) 2.7.7.6 (50%)" "Transferring groups other than amino-acyl groups (50%) DNA-directed RNA polymerase (50%)" "GO:0006351 (4%) GO:0045944 (4%) GO:0006357 (3.2%)" "GO:0005634 (7.9%) GO:0016324 (1.6%) GO:0033281 (1.6%)" "GO:0008270 (7.1%) GO:0000981 (4%) GO:0043565 (4%)" "DNA-templated transcription (4%) positive regulation of transcription by RNA polymerase II (4%) regulation of transcription by RNA polymerase II (3.2%)" "nucleus (7.9%) apical plasma membrane (1.6%) TAT protein transport complex (1.6%)" "zinc ion binding (7.1%) DNA-binding transcription factor activity, RNA polymerase II-specific (4%) sequence-specific DNA binding (4%)" "IPR011990 (16.7%) IPR019734 (7.2%) IPR007219 (3.6%)" "Tetratricopeptide-like helical domain superfamily (16.7%) Tetratricopeptide repeat (7.2%) Xylanolytic transcriptional activator, regulatory domain (3.6%)" GQLDECDNQLMDLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.5 (100%) chorismate mutase (100%) "GO:0046417 (48.4%) GO:0009697 (3.2%)" GO:0004106 (48.4%) "chorismate metabolic process (48.4%) salicylic acid biosynthetic process (3.2%)" chorismate mutase activity (48.4%) "IPR002701 (19%) IPR006218 (17.7%) IPR052899 (17.7%)" "Chorismate mutase II, prokaryotic-type (19%) DAHP synthetase I/KDSA (17.7%) Class-I DAHP synthase (17.7%)" LQPGEFVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR031704 (13.1%) IPR002252 (12.8%) IPR031705 (12.8%)" "Glycosyl hydrolase family 36, N-terminal (13.1%) Glycoside hydrolase family 36 (12.8%) Glycosyl hydrolase family 36, C-terminal (12.8%)" FEFRPLEPGFGVTLGNALR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR011773 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) DNA-directed RNA polymerase, alpha subunit (16.7%)" DRWDVLR root "4.2.1.9 (63.3%) 4.1.1.20 (16.7%) 3.2.1.28 (10%)" "dihydroxy-acid dehydratase (63.3%) diaminopimelate decarboxylase (16.7%) alpha,alpha-trehalase (10%)" "GO:0006508 (17.5%) GO:0009097 (7.4%) GO:0009099 (7.4%)" "GO:0005829 (7.4%) GO:0016020 (2.6%) GO:0005886 (0.4%)" "GO:0008236 (17.5%) GO:0000287 (7.4%) GO:0004160 (7.4%)" "proteolysis (17.5%) isoleucine biosynthetic process (7.4%) L-valine biosynthetic process (7.4%)" "cytosol (7.4%) membrane (2.6%) plasma membrane (0.4%)" "serine-type peptidase activity (17.5%) magnesium ion binding (7.4%) dihydroxy-acid dehydratase activity (7.4%)" "IPR029058 (13.4%) IPR052920 (13.4%) IPR001375 (13.1%)" "Alpha/Beta hydrolase fold (13.4%) Potential DNA-binding regulatory protein (13.4%) Peptidase S9, prolyl oligopeptidase, catalytic domain (13.1%)" HLVNVLLR root "GO:0006397 (6.9%) GO:0006406 (6.9%) GO:0002115 (2%)" "GO:0005886 (13.9%) GO:0000445 (6.9%) GO:0005789 (2%)" "GO:0016491 (10.9%) GO:0003729 (6.9%) GO:0003700 (3%)" "mRNA processing (6.9%) mRNA export from nucleus (6.9%) store-operated calcium entry (2%)" "plasma membrane (13.9%) THO complex part of transcription export complex (6.9%) endoplasmic reticulum membrane (2%)" "oxidoreductase activity (10.9%) mRNA binding (6.9%) DNA-binding transcription factor activity (3%)" "IPR050369 (7%) IPR013112 (6.4%) IPR013121 (6.4%)" "Respiratory burst oxidase/Ferric reductase (7%) FAD-binding 8 (6.4%) Ferric reductase, NAD binding domain (6.4%)" LFYGVDK root "2.1.2.1 (73.3%) 2.7.1.107 (6.7%) 2.7.1.138 (6.7%)" "glycine hydroxymethyltransferase (73.3%) diacylglycerol kinase (ATP) (6.7%) ceramide kinase (6.7%)" "GO:0019264 (5.7%) GO:0035999 (5.7%) GO:0032259 (3.8%)" "GO:0005829 (6.4%) GO:0016020 (5.1%) GO:0019867 (3.8%)" "GO:0004372 (5.7%) GO:0030170 (5.7%) GO:0005509 (3.8%)" "glycine biosynthetic process from serine (5.7%) tetrahydrofolate interconversion (5.7%) methylation (3.8%)" "cytosol (6.4%) membrane (5.1%) outer membrane (3.8%)" "glycine hydroxymethyltransferase activity (5.7%) pyridoxal phosphate binding (5.7%) calcium ion binding (3.8%)" "IPR001085 (4.9%) IPR015421 (4.9%) IPR015422 (4.9%)" "Serine hydroxymethyltransferase (4.9%) Pyridoxal phosphate-dependent transferase, major domain (4.9%) Pyridoxal phosphate-dependent transferase, small domain (4.9%)" ELVLEVQQHLGEDTVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (21.8%) GO:0045259 (21.8%)" "GO:0005524 (21.8%) GO:0046933 (21.8%) GO:0016787 (12.8%)" "plasma membrane (21.8%) proton-transporting ATP synthase complex (21.8%)" "ATP binding (21.8%) proton-transporting ATP synthase activity, rotational mechanism (21.8%) hydrolase activity (12.8%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" SGSYYGGLTWLGDNFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.6%) IPR012910 (20.6%) IPR039426 (20.6%)" "TonB-dependent receptor-like, beta-barrel (20.6%) TonB-dependent receptor, plug domain (20.6%) TonB-dependent receptor-like (20.6%)" LLNLVNQLLDFRK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.13.3 (100%) histidine kinase (100%) GO:0006508 (0.1%) GO:0016020 (13%) "GO:0000155 (22.7%) GO:0003700 (22.5%) GO:0043565 (22.5%)" proteolysis (0.1%) membrane (13%) "phosphorelay sensor kinase activity (22.7%) DNA-binding transcription factor activity (22.5%) sequence-specific DNA binding (22.5%)" "IPR003594 (6.8%) IPR005467 (6.8%) IPR018060 (6.8%)" "Histidine kinase/HSP90-like ATPase domain (6.8%) Histidine kinase domain (6.8%) AraC-like, DNA binding HTH domain (6.8%)" LLQVADYDYFGDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) LNTYALDYKVEGGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (43.8%) "GO:0052689 (43.8%) GO:0004557 (12.5%)" cell outer membrane (43.8%) "carboxylic ester hydrolase activity (43.8%) alpha-galactosidase activity (12.5%)" "IPR032812 (26.9%) IPR044060 (26.9%) IPR011050 (23.1%)" "SbsA, Ig-like domain (26.9%) Bacterial repeat domain (26.9%) Pectin lyase fold/virulence factor (23.1%)" SQHHMDQALADYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.69 (100%) gluconate 5-dehydrogenase (100%) "GO:0008874 (55.6%) GO:0016491 (38.9%) GO:0016616 (5.6%)" "gluconate 5-dehydrogenase activity (55.6%) oxidoreductase activity (38.9%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (5.6%)" "IPR002347 (31.7%) IPR036291 (31.7%) IPR020904 (30%)" "Short-chain dehydrogenase/reductase SDR (31.7%) NAD(P)-binding domain superfamily (31.7%) Short-chain dehydrogenase/reductase, conserved site (30%)" YYECELDGQKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (25%) GO:0005886 (25%) "GO:0010181 (25%) GO:0016655 (25%)" sodium ion transport (25%) plasma membrane (25%) "FMN binding (25%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (25%)" "IPR007329 (50%) IPR010204 (50%)" "FMN-binding (50%) Na(+)-translocating NADH-quinone reductase subunit C (50%)" HLDDAVYHMSYGKDELDNMTDEQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (36.4%) IPR012944 (33.3%) IPR033985 (30.3%)" "Tetratricopeptide-like helical domain superfamily (36.4%) RagB/SusD domain (33.3%) SusD-like, N-terminal (30.3%)" NLTDTNYNTFAVDNAATGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.4%) GO:0006811 (3.6%)" GO:0009279 (50%) "iron ion transport (46.4%) monoatomic ion transport (3.6%)" cell outer membrane (50%) "IPR000531 (25.7%) IPR039426 (25.7%) IPR012910 (24.8%)" "TonB-dependent receptor-like, beta-barrel (25.7%) TonB-dependent receptor-like (25.7%) TonB-dependent receptor, plug domain (24.8%)" VAAEAASVPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LKPGGLLLYDGYGVMNPPQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016903 (100%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (100%) "IPR002869 (33.3%) IPR019752 (33.3%) IPR052554 (33.3%)" "Pyruvate-flavodoxin oxidoreductase, central domain (33.3%) Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (33.3%) 2-oxoglutarate synthase subunit KorC (33.3%)" LQLALALK root "2.1.1.14 (77.3%) 3.6.1.- (11.8%) 4.2.1.19 (4.4%)" "5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (77.3%) In phosphorus-containing anhydrides (11.8%) imidazoleglycerol-phosphate dehydratase (4.4%)" "GO:0032259 (16.1%) GO:0009086 (15.7%) GO:0045900 (2.7%)" "GO:0005737 (3.3%) GO:0016020 (0.6%) GO:0005634 (0.5%)" "GO:0008270 (15.9%) GO:0003871 (15.8%) GO:0005524 (3.4%)" "methylation (16.1%) methionine biosynthetic process (15.7%) negative regulation of translational elongation (2.7%)" "cytoplasm (3.3%) membrane (0.6%) nucleus (0.5%)" "zinc ion binding (15.9%) 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (15.8%) ATP binding (3.4%)" "IPR002629 (16%) IPR038071 (16%) IPR013215 (15.9%)" "Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (16%) UROD/MetE-like superfamily (16%) Cobalamin-independent methionine synthase MetE, N-terminal (15.9%)" NLLEEWYEHYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006139 (20%) "GO:0003677 (20%) GO:0004386 (20%) GO:0005524 (20%)" nucleobase-containing compound metabolic process (20%) "DNA binding (20%) helicase activity (20%) ATP binding (20%)" "IPR006555 (25%) IPR006935 (25%) IPR014001 (25%)" "ATP-dependent helicase, C-terminal (25%) Helicase/UvrB, N-terminal (25%) Helicase superfamily 1/2, ATP-binding domain (25%)" DVEEFMAANKE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.11.9 (100%) Xaa-Pro aminopeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0030145 (25%) GO:0070006 (25%)" proteolysis (25%) cytosol (25%) "manganese ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000994 (20.4%) IPR007865 (20.4%) IPR052433 (20.4%)" "Peptidase M24 (20.4%) Aminopeptidase P, N-terminal (20.4%) Xaa-Pro dipeptidase-like (20.4%)" FPSQLPFK root 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006261 (2.5%) GO:0006351 (2.5%) GO:0097681 (2.5%)" "GO:0016020 (17.5%) GO:0000428 (2.5%) GO:0005634 (2.5%)" "GO:0000155 (20%) GO:0003700 (17.5%) GO:0043565 (17.5%)" "DNA-templated DNA replication (2.5%) DNA-templated transcription (2.5%) double-strand break repair via alternative nonhomologous end joining (2.5%)" "membrane (17.5%) DNA-directed RNA polymerase complex (2.5%) nucleus (2.5%)" "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (17.5%) sequence-specific DNA binding (17.5%)" "IPR015943 (11.5%) IPR011110 (10.3%) IPR001789 (9%)" "WD40/YVTN repeat-like-containing domain superfamily (11.5%) Two component regulator propeller (10.3%) Signal transduction response regulator, receiver domain (9%)" CVPFAYEQTPGVDMVSGKPAVAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR004499 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Proline-tRNA ligase, class IIa, archaeal-type (11.3%)" GVELQLDTHNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LNEDCLFLSAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0043022 (20%)" cytoplasm (20%) "GTPase activity (20%) GTP binding (20%) ribosome binding (20%)" "IPR005225 (12.8%) IPR006073 (12.8%) IPR016496 (12.8%)" "Small GTP-binding domain (12.8%) GTP binding domain (12.8%) GTPase HflX (12.8%)" PLQWENECTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (7.9%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (7.9%)" "IPR004463 (14.8%) IPR010084 (14.8%) IPR013114 (14.8%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.8%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.8%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%)" LVTVGENVTLTYTSQVDCHPMENALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MLGLGLTMPSLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR039968 (51.8%) IPR016181 (48.2%)" "Bacterial ceramide synthase-like (51.8%) Acyl-CoA N-acyltransferase (48.2%)" TKDFAWNLNLNATHYTNELTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR036942 (13.3%) IPR039426 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.3%) TonB-dependent receptor-like (13.3%)" LLTEVSAAVAK Pseudomonadati Bacteria Pseudomonadati 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.4%) "GO:0051287 (17.6%) GO:0046872 (17.4%) GO:0016746 (17%)" malate metabolic process (16.4%) "NAD binding (17.6%) metal ion binding (17.4%) acyltransferase activity (17%)" "IPR012302 (9.2%) IPR051674 (9.2%) IPR012301 (9.1%)" "Malic enzyme, NAD-binding (9.2%) Malate Decarboxylating Enzymes (9.2%) Malic enzyme, N-terminal domain (9.1%)" QTGLTHEHTLSASGGTDKFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" YSSSNNYFGYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" EMVLGTLK root "1.5.-.- (25%) 1.5.5.2 (25%) 2.1.1.61 (25%)" "Acting on the CH-NH group of donors (25%) proline dehydrogenase (25%) tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase (25%)" "GO:0002098 (2.2%) GO:0006264 (2.2%) GO:0006396 (2.2%)" "GO:0005737 (6.5%) GO:0005576 (2.2%) GO:0005739 (2.2%)" "GO:0005524 (6.5%) GO:0003677 (4.3%) GO:0016787 (4.3%)" "tRNA wobble uridine modification (2.2%) mitochondrial DNA replication (2.2%) RNA processing (2.2%)" "cytoplasm (6.5%) extracellular region (2.2%) mitochondrion (2.2%)" "ATP binding (6.5%) DNA binding (4.3%) hydrolase activity (4.3%)" "IPR008136 (22.1%) IPR036653 (19.5%) IPR029063 (3.9%)" "CinA, C-terminal (22.1%) CinA-like, C-terminal (19.5%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (3.9%)" NAGGLVLSPFDSAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.1 (100%) carbonic anhydrase (100%) "GO:0004089 (50%) GO:0008270 (50%)" "carbonate dehydratase activity (50%) zinc ion binding (50%)" "IPR001765 (50%) IPR036874 (50%)" "Carbonic anhydrase (50%) Carbonic anhydrase superfamily (50%)" TNTTCLFLNQLR Bacteria Bacteria "GO:0006281 (13.2%) GO:0006310 (13.2%) GO:0009432 (10.6%)" GO:0005829 (13.2%) "GO:0003697 (13.2%) GO:0005524 (13.2%) GO:0140664 (13.2%)" "DNA repair (13.2%) DNA recombination (13.2%) SOS response (10.6%)" cytosol (13.2%) "single-stranded DNA binding (13.2%) ATP binding (13.2%) ATP-dependent DNA damage sensor activity (13.2%)" "IPR013765 (11.7%) IPR020584 (11.7%) IPR020587 (11.7%)" "DNA recombination and repair protein RecA (11.7%) DNA recombination/repair protein RecA, conserved site (11.7%) DNA recombination and repair protein RecA, monomer-monomer interface (11.7%)" YLTVGGVLDYTYSSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.2%) IPR023997 (15.2%) IPR039426 (15.2%)" "TonB-dependent receptor, plug domain (15.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.2%) TonB-dependent receptor-like (15.2%)" LSAYLAFVPLNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002625 (26.3%) IPR018598 (26.3%) IPR036063 (23.8%)" "Smr domain (26.3%) Domain of unknown function DUF2027 (26.3%) Smr domain superfamily (23.8%)" TVMVSDDAR root "3.2.1.22 (35.3%) 3.2.1.20 (23.5%) 3.2.1.3 (23.5%)" "alpha-galactosidase (35.3%) alpha-glucosidase (23.5%) glucan 1,4-alpha-glucosidase (23.5%)" GO:0016020 (0.3%) "GO:0030246 (59.1%) GO:0016787 (36.3%) GO:0004557 (1.2%)" membrane (0.3%) "carbohydrate binding (59.1%) hydrolase activity (36.3%) alpha-galactosidase activity (1.2%)" "IPR029486 (14.5%) IPR052720 (14.5%) IPR019563 (14.3%)" "Glycosyl-hydrolase 97, N-terminal domain (14.5%) Glycosyl Hydrolase Family 97 (14.5%) Glycosyl-hydrolase 97, catalytic domain (14.3%)" YCGVWWNMLVGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.2%) GO:0016787 (48.8%)" "carbohydrate binding (51.2%) hydrolase activity (48.8%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" KVDFDYCSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25.5%) IPR035376 (25.5%) IPR038143 (24.5%)" "NigD-like N-terminal OB domain (25.5%) NigD-like, C-terminal domain (25.5%) NigD-like, C-terminal domain superfamily (24.5%)" AEKLEAYVDNVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.9%) "GO:0004222 (33.9%) GO:0046872 (32.2%)" proteolysis (33.9%) "metalloendopeptidase activity (33.9%) metal ion binding (32.2%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" ALTNWNNLQLGLTNPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) DFQLLDEQKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0055085 (23.3%) "GO:0043190 (23.3%) GO:0005886 (2.3%)" "GO:0005524 (25.6%) GO:0016887 (25.6%)" transmembrane transport (23.3%) "ATP-binding cassette (ABC) transporter complex (23.3%) plasma membrane (2.3%)" "ATP binding (25.6%) ATP hydrolysis activity (25.6%)" "IPR003439 (21.2%) IPR051120 (21.2%) IPR003593 (19.2%)" "ABC transporter-like, ATP-binding domain (21.2%) ABC Transporter, Amino Acid and LPS Transport (21.2%) AAA+ ATPase domain (19.2%)" LPVLGLCYGAQFLSYAQGGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.8%) "GO:0003921 (32.8%) GO:0005524 (32.8%) GO:0016740 (1.6%)" cytosol (32.8%) "GMP synthase activity (32.8%) ATP binding (32.8%) transferase activity (1.6%)" "IPR004739 (12.9%) IPR017926 (12.9%) IPR029062 (12.9%)" "GMP synthase, glutamine amidotransferase (12.9%) Glutamine amidotransferase (12.9%) Class I glutamine amidotransferase-like (12.9%)" FNTLEQLVEALGLPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (20%) GO:0006164 (13.6%) GO:0006189 (6.4%)" "GO:0004044 (20%) GO:0046872 (20%) GO:0051536 (20%)" "purine nucleobase biosynthetic process (20%) purine nucleotide biosynthetic process (13.6%) 'de novo' IMP biosynthetic process (6.4%)" "amidophosphoribosyltransferase activity (20%) metal ion binding (20%) iron-sulfur cluster binding (20%)" "IPR000836 (21.4%) IPR017932 (20.6%) IPR029057 (19.8%)" "Phosphoribosyltransferase domain (21.4%) Glutamine amidotransferase type 2 domain (20.6%) Phosphoribosyltransferase-like (19.8%)" GYAGWTSQDANLGGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) KLPNGLEGLLNDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.8%) IPR031704 (12.8%) IPR031705 (12.8%)" "Glycoside hydrolase family 36 (12.8%) Glycosyl hydrolase family 36, N-terminal (12.8%) Glycosyl hydrolase family 36, C-terminal (12.8%)" TLTFAYK root "2.7.11.1 (50%) 3.6.4.12 (50%)" "non-specific serine/threonine protein kinase (50%) DNA helicase (50%)" "GO:0006952 (3%) GO:0006508 (2.4%) GO:0007338 (1.2%)" "GO:0009279 (14.3%) GO:0005886 (6%) GO:0016020 (2.4%)" "GO:0052689 (13.1%) GO:0004557 (5.4%) GO:0005524 (3%)" "defense response (3%) proteolysis (2.4%) single fertilization (1.2%)" "cell outer membrane (14.3%) plasma membrane (6%) membrane (2.4%)" "carboxylic ester hydrolase activity (13.1%) alpha-galactosidase activity (5.4%) ATP binding (3%)" "IPR032812 (8.3%) IPR044060 (8.3%) IPR011050 (8%)" "SbsA, Ig-like domain (8.3%) Bacterial repeat domain (8.3%) Pectin lyase fold/virulence factor (8%)" DTADLLNQLLLESQELLENHPFNVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) GO:0006096 (32.9%) "GO:0004619 (32.9%) GO:0046872 (32.9%) GO:0016301 (1.4%)" glycolytic process (32.9%) "phosphoglycerate mutase activity (32.9%) metal ion binding (32.9%) kinase activity (1.4%)" "IPR004456 (25%) IPR006124 (25%) IPR017850 (25%)" "2,3-bisphosphoglycerate-independent phosphoglycerate mutase (25%) Metalloenzyme (25%) Alkaline-phosphatase-like, core domain superfamily (25%)" TALSTNHNVSLQGGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" VDGSDVLPTVLNLWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (63.6%) 1.6.5.9 (36.4%)" "Transferred entry: 1.6.5.9 (63.6%) NADH:ubiquinone reductase (non-electrogenic) (36.4%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" HLKLELGLFGSQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FVSQTVNSKDPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0043093 (31.1%) GO:0051301 (2.2%)" "GO:0009898 (33.3%) GO:0032153 (33.3%)" "FtsZ-dependent cytokinesis (31.1%) cell division (2.2%)" "cytoplasmic side of plasma membrane (33.3%) cell division site (33.3%)" "IPR050696 (26.3%) IPR003494 (24.6%) IPR020823 (24.6%)" "Bacterial cell division protein FtsA/MreB (26.3%) SHS2 domain inserted in FtsA (24.6%) Cell division protein FtsA (24.6%)" HNDLLAANVSQVLLPVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006354 (20.8%) GO:0031564 (20.8%) GO:0006353 (18.9%)" GO:0005829 (20.8%) "DNA-templated transcription elongation (20.8%) transcription antitermination (20.8%) DNA-templated transcription termination (18.9%)" cytosol (20.8%) "IPR006645 (13.1%) IPR036735 (13.1%) IPR043425 (13.1%)" "NusG-like, N-terminal (13.1%) NusG, N-terminal domain superfamily (13.1%) NusG-like (13.1%)" CDKGFGVNNTGLAVFLDFSESLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (14.5%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (14.5%)" "IPR003953 (14.3%) IPR011280 (14.3%) IPR015939 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%)" YSTLPAGDYKFEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.3%) "GO:0000155 (25.2%) GO:0003700 (25.2%) GO:0043565 (25.2%)" membrane (24.3%) "phosphorelay sensor kinase activity (25.2%) DNA-binding transcription factor activity (25.2%) sequence-specific DNA binding (25.2%)" "IPR011110 (12.6%) IPR011123 (12.6%) IPR018060 (12.6%)" "Two component regulator propeller (12.6%) Two component regulator three Y (12.6%) AraC-like, DNA binding HTH domain (12.6%)" PEEVVDFATR Pseudomonadati Bacteria Pseudomonadati "4.1.2.13 (95.8%) 4.1.2.- (4.2%)" "fructose-bisphosphate aldolase (95.8%) Aldehyde-lyases (4.2%)" "GO:0006096 (18.5%) GO:0030388 (18.5%) GO:0005975 (8.6%)" "GO:0008270 (27.2%) GO:0004332 (19.4%) GO:0016832 (7.8%)" "glycolytic process (18.5%) fructose 1,6-bisphosphate metabolic process (18.5%) carbohydrate metabolic process (8.6%)" "zinc ion binding (27.2%) fructose-bisphosphate aldolase activity (19.4%) aldehyde-lyase activity (7.8%)" "IPR000771 (27.2%) IPR013785 (27.2%) IPR050246 (27.2%)" "Fructose-bisphosphate aldolase, class-II (27.2%) Aldolase-type TIM barrel (27.2%) Class II Fructose-bisphosphate Aldolase (27.2%)" VENSDYDMTVSGVYFPSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NYVSSLYTLNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (52%) IPR036737 (48%)" "Domain of unknown function DUF3868 (52%) OmpA-like domain superfamily (48%)" TGALLLAPSVNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR013105 (25.4%) IPR019734 (25.4%) IPR025738 (25.4%)" "Tetratricopeptide repeat 2 (25.4%) Tetratricopeptide repeat (25.4%) Aerotolerance-related protein BatD (25.4%)" EYQPYKGELSR Bacteria Bacteria 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0000027 (10.3%) GO:0009409 (8.4%) GO:0010467 (8.4%)" "GO:0005829 (10.3%) GO:1990904 (10.3%)" "GO:0000049 (10.3%) GO:0003924 (10.3%) GO:0005525 (10.3%)" "ribosomal large subunit assembly (10.3%) response to cold (8.4%) gene expression (8.4%)" "cytosol (10.3%) ribonucleoprotein complex (10.3%)" "tRNA binding (10.3%) GTPase activity (10.3%) GTP binding (10.3%)" "IPR000640 (6.7%) IPR000795 (6.7%) IPR005225 (6.7%)" "Elongation factor EFG, domain V-like (6.7%) Translational (tr)-type GTP-binding domain (6.7%) Small GTP-binding domain (6.7%)" ACLGWLDLTVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) "IPR003961 (22.7%) IPR008757 (22.7%) IPR013783 (18.2%)" "Fibronectin type III (22.7%) Peptidase M6-like, domain (22.7%) Immunoglobulin-like fold (18.2%)" GLGFEVMFQGVDHVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" LQQVPGYESDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (20.6%) IPR001375 (20%) IPR002469 (20%)" "WD40-like beta-propeller (20.6%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20%) Dipeptidylpeptidase IV, N-terminal domain (20%)" PFEPSSDPLLAELQALVAPLEVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013118 (17.3%) IPR050988 (17.3%) IPR013131 (16.8%)" "Mannitol dehydrogenase, C-terminal (17.3%) Mannitol Dehydrogenase/Oxidoreductase (17.3%) Mannitol dehydrogenase, N-terminal (16.8%)" STLLDALCLALYNR Pseudomonadati Bacteria Pseudomonadati GO:0006302 (47.3%) "GO:0016887 (47.3%) GO:0004527 (5.4%)" double-strand break repair (47.3%) "ATP hydrolysis activity (47.3%) exonuclease activity (5.4%)" "IPR027417 (50.6%) IPR038729 (49.4%)" "P-loop containing nucleoside triphosphate hydrolase (50.6%) Rad50/SbcC-type AAA domain (49.4%)" AYSNYTSPLGAAMLMNR Bacteria Bacteria 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (27.5%) GO:0046677 (26.8%)" GO:0016020 (18.2%) GO:0008800 (27.5%) "beta-lactam antibiotic catabolic process (27.5%) response to antibiotic (26.8%)" membrane (18.2%) beta-lactamase activity (27.5%) "IPR045155 (25.6%) IPR012338 (25.3%) IPR000871 (24.9%)" "Beta-lactamase class A, catalytic domain (25.6%) Beta-lactamase/transpeptidase-like (25.3%) Beta-lactamase, class-A (24.9%)" GVLLLPTLEEAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20%) GO:0006189 (19.9%)" "GO:0004637 (20%) GO:0005524 (20%) GO:0046872 (20%)" "purine nucleobase biosynthetic process (20%) 'de novo' IMP biosynthetic process (19.9%)" "phosphoribosylamine-glycine ligase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000115 (11.2%) IPR011761 (11.2%) IPR020561 (11.2%)" "Phosphoribosylglycinamide synthetase (11.2%) ATP-grasp fold (11.2%) Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (11.2%)" STTQLVEMSNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (50%) IPR029052 (50%)" "Fructose-1,6-bisphosphatase class 3 (50%) Metallo-dependent phosphatase-like (50%)" LNLLGLR root "4.2.1.10 (51.1%) 1.1.1.49 (13.2%) 2.3.1.129 (8.8%)" "3-dehydroquinate dehydratase (51.1%) glucose-6-phosphate dehydrogenase (NADP(+)) (13.2%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (8.8%)" "GO:0019631 (6.3%) GO:0008652 (5.9%) GO:0009073 (5.9%)" "GO:0016020 (4.9%) GO:0005829 (2.3%) GO:0005886 (1.7%)" "GO:0003855 (6.3%) GO:0004672 (6.3%) GO:0005524 (4.6%)" "quinate catabolic process (6.3%) amino acid biosynthetic process (5.9%) aromatic amino acid family biosynthetic process (5.9%)" "membrane (4.9%) cytosol (2.3%) plasma membrane (1.7%)" "3-dehydroquinate dehydratase activity (6.3%) protein kinase activity (6.3%) ATP binding (4.6%)" "IPR027417 (7.1%) IPR001874 (6.1%) IPR036441 (6.1%)" "P-loop containing nucleoside triphosphate hydrolase (7.1%) Dehydroquinase, class II (6.1%) Dehydroquinase, class II superfamily (6.1%)" LKANTLPGLFSTATLDEQTGEVLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.6%) IPR010720 (14.6%) IPR051563 (14.6%)" "Carbohydrate-binding, CenC-like (14.6%) Alpha-L-arabinofuranosidase, C-terminal (14.6%) Glycosyl Hydrolase Family 51 (14.6%)" LLKVDPFQVLDQEGVGQLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (97.4%) 2.7.-.- (2.6%)" "pyruvate, phosphate dikinase (97.4%) Transferring phosphorus-containing groups (2.6%)" "GO:0050242 (25.5%) GO:0005524 (24.8%) GO:0016301 (24.8%)" "pyruvate, phosphate dikinase activity (25.5%) ATP binding (24.8%) kinase activity (24.8%)" "IPR000121 (10.1%) IPR010121 (10.1%) IPR015813 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate, phosphate dikinase (10.1%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.1%)" NTHVQFDMPAVDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR003741 (34.9%) IPR024185 (32.6%) IPR037171 (32.6%)" "LUD domain (34.9%) 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily (32.6%) NagB/RpiA transferase-like (32.6%)" EGTLENLEQLLDRFEELNANYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032533 (34.1%) IPR049208 (34.1%) IPR011004 (31.7%)" "Domain of unknown function DUF4954 (34.1%) Domain of unknown function DUF6819 (34.1%) Trimeric LpxA-like superfamily (31.7%)" PLYQFWGYQTDGVYKDFEDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" HDVVALQVYDPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR002881 (40.3%) IPR036465 (39%) IPR002035 (20.8%)" "Domain of unknown function DUF58 (40.3%) von Willebrand factor A-like domain superfamily (39%) von Willebrand factor, type A (20.8%)" HLPFASVSDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.4.1.13 (100%) cysteine-S-conjugate beta-lyase (100%) "GO:0016829 (49.1%) GO:0030170 (49.1%) GO:0008483 (1.8%)" "lyase activity (49.1%) pyridoxal phosphate binding (49.1%) transaminase activity (1.8%)" "IPR004839 (17.1%) IPR051798 (17.1%) IPR015421 (16.5%)" "Aminotransferase, class I/classII, large domain (17.1%) Class-II Pyridoxal-Phosphate-Dependent Aminotransferase (17.1%) Pyridoxal phosphate-dependent transferase, major domain (16.5%)" AFDELYGLYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR007627 (12.5%) IPR013249 (12.5%) IPR013324 (12.5%)" "RNA polymerase sigma-70 region 2 (12.5%) RNA polymerase sigma factor 70, region 4 type 2 (12.5%) RNA polymerase sigma factor, region 3/4-like (12.5%)" GKELSSLDLEHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR030890 (100%) Substrate import-associated zinc metallohydrolase lipoprotein (100%) AANLEPLSVALVNLTEALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045691 (100%) Protein of unknown function DUF6056 (100%) SDVLNNANLRPGDVLVGLSSTGQATYEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.7%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.7%)" "IPR004733 (20%) IPR010918 (20%) IPR016188 (20%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, C-terminal domain (20%) PurM-like, N-terminal domain (20%)" VAETLNFSEASR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR000847 (20.3%) IPR005119 (20.3%) IPR050950 (20.3%)" "LysR, HTH, N-terminal domain (20.3%) LysR, substrate-binding (20.3%) HTH-type LysR transcriptional regulators (20.3%)" TVADSYQAGVESMDFTSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005615 (50%) GO:0004867 (50%) extracellular space (50%) serine-type endopeptidase inhibitor activity (50%) "IPR000215 (16.7%) IPR023795 (16.7%) IPR023796 (16.7%)" "Serpin family (16.7%) Serpin, conserved site (16.7%) Serpin domain (16.7%)" VVVDNLPFLLADTVGFLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005737 (20.2%) "GO:0005525 (20.2%) GO:0043022 (20.2%) GO:0003924 (19.6%)" cytoplasm (20.2%) "GTP binding (20.2%) ribosome binding (20.2%) GTPase activity (19.6%)" "IPR006073 (13.3%) IPR016496 (13.3%) IPR030394 (13.3%)" "GTP binding domain (13.3%) GTPase HflX (13.3%) HflX-type guanine nucleotide-binding (G) domain (13.3%)" VEVDENGEAVKQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (46.7%) GO:0009279 (53.3%) iron ion transport (46.7%) cell outer membrane (53.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EWNPQQYAEYNEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0022857 (50%) membrane (50%) transmembrane transporter activity (50%) "IPR011701 (51.9%) IPR036259 (48.1%)" "Major facilitator superfamily (51.9%) MFS transporter superfamily (48.1%)" DYRPLVQVLDNLER Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005975 (12.5%) "GO:0016798 (62.5%) GO:0004553 (12.5%) GO:0016787 (12.5%)" carbohydrate metabolic process (12.5%) "hydrolase activity, acting on glycosyl bonds (62.5%) hydrolase activity, hydrolyzing O-glycosyl compounds (12.5%) hydrolase activity (12.5%)" "IPR051913 (34.8%) IPR008979 (31.9%) IPR017853 (31.9%)" "Glycosyl Hydrolase 2 Domain-Containing Protein (34.8%) Galactose-binding-like domain superfamily (31.9%) Glycoside hydrolase superfamily (31.9%)" DKLNYAATLQLTYNLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.2%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.2%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" EVLGEGGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TDNTLKPYVLGLDLGGTNSVFGLVDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) "IPR000600 (35.2%) IPR049874 (33.3%) IPR043129 (31.5%)" "ROK family (35.2%) ROK, conserved site (33.3%) ATPase, nucleotide binding domain (31.5%)" TLVFCADETHAER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006304 (16.7%) GO:0005829 (17.6%) "GO:0003677 (17.6%) GO:0005524 (17.6%) GO:0016787 (17.6%)" DNA modification (16.7%) cytosol (17.6%) "DNA binding (17.6%) ATP binding (17.6%) hydrolase activity (17.6%)" "IPR006935 (17%) IPR014001 (17%) IPR029464 (17%)" "Helicase/UvrB, N-terminal (17%) Helicase superfamily 1/2, ATP-binding domain (17%) Type I restriction enzyme R protein, N-terminal domain (17%)" TPLTLLLSPLVSMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20%) "GO:0000155 (20%) GO:0003700 (20%) GO:0005524 (20%)" membrane (20%) "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR001789 (6.7%) IPR003594 (6.7%) IPR003661 (6.7%)" "Signal transduction response regulator, receiver domain (6.7%) Histidine kinase/HSP90-like ATPase domain (6.7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.7%)" LTFYADYYYKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" KLDPYLEFTFLTGLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (44.5%) IPR012547 (37.8%) IPR027417 (17.6%)" "AAA-ATPase-like domain (44.5%) PD-(D/E)XK nuclease superfamily 9 (37.8%) P-loop containing nucleoside triphosphate hydrolase (17.6%)" LGYPAPELR Bacteria Bacteria 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (19.9%) GO:0005737 (19.9%) "GO:0046872 (20.4%) GO:0004642 (19.9%) GO:0005524 (19.9%)" 'de novo' IMP biosynthetic process (19.9%) cytoplasm (19.9%) "metal ion binding (20.4%) phosphoribosylformylglycinamidine synthase activity (19.9%) ATP binding (19.9%)" "IPR010073 (11.1%) IPR010918 (11.1%) IPR040707 (11.1%)" "Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.1%)" AGYTEDDVNALADSDLLGELLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32%)" DCCLEFNSLSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.- (100%) Transaminases (100%) "GO:0008483 (50%) GO:0030170 (50%)" "transaminase activity (50%) pyridoxal phosphate binding (50%)" "IPR004838 (17.4%) IPR004839 (17.4%) IPR050881 (17.4%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (17.4%) Aminotransferase, class I/classII, large domain (17.4%) LL-diaminopimelate aminotransferase (17.4%)" WLYSDMR root GO:0005886 (23.1%) "GO:0005524 (23.1%) GO:0016887 (23.1%) GO:0015421 (15.4%)" plasma membrane (23.1%) "ATP binding (23.1%) ATP hydrolysis activity (23.1%) ABC-type oligopeptide transporter activity (15.4%)" "IPR045741 (36.9%) IPR047799 (36.9%) IPR003439 (3.6%)" "Type IX secretion system protein PorV (36.9%) Type IX secretion system, outer membrane channel protein PorV (36.9%) ABC transporter-like, ATP-binding domain (3.6%)" MTGDFSLYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.1%) IPR008930 (19.1%) IPR051802 (19.1%)" "Alpha-2-macroglobulin (19.1%) Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (19.1%) Alpha-2-macroglobulin-like (19.1%)" FDLPHAVLYLGYDFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) IPR023614 (100%) Porin domain superfamily (100%) RGDEYLTDNLLATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR004680 (25%) IPR006037 (25%) IPR036721 (25%)" "Citrate transporter-like domain (25%) Regulator of K+ conductance, C-terminal (25%) Regulator of K+ conductance, C-terminal domain superfamily (25%)" LNEKELSVEDFNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.7%) GO:0043335 (15.7%) GO:0051083 (15.7%)" GO:0005737 (5.6%) "GO:0003755 (15.7%) GO:0043022 (15.7%) GO:0044183 (15.7%)" "protein transport (15.7%) protein unfolding (15.7%) 'de novo' cotranslational protein folding (15.7%)" cytoplasm (5.6%) "peptidyl-prolyl cis-trans isomerase activity (15.7%) ribosome binding (15.7%) protein folding chaperone (15.7%)" "IPR005215 (19%) IPR008881 (19%) IPR027304 (18.4%)" "Trigger factor (19%) Trigger factor, ribosome-binding, bacterial (19%) Trigger factor/SurA domain superfamily (18.4%)" FTQTDLDGGGDKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.3%) IPR033985 (35.3%) IPR011990 (29.4%)" "RagB/SusD domain (35.3%) SusD-like, N-terminal (35.3%) Tetratricopeptide-like helical domain superfamily (29.4%)" LVVKEEDEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (14.6%) IPR004602 (14.6%) IPR017871 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) UvrABC system subunit A (14.6%) ABC transporter-like, conserved site (14.6%)" AVSLEDLK root "2.2.1.1 (70.9%) 4.1.1.48 (10.5%) 1.17.7.1 (3.5%)" "transketolase (70.9%) indole-3-glycerol-phosphate synthase (10.5%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) (3.5%)" "GO:0009052 (7.1%) GO:0019253 (2.5%) GO:0006396 (1.6%)" "GO:0005737 (9.3%) GO:0005829 (7.9%) GO:0005634 (1.9%)" "GO:0046872 (9.9%) GO:0003746 (9%) GO:0004802 (7.6%)" "pentose-phosphate shunt, non-oxidative branch (7.1%) reductive pentose-phosphate cycle (2.5%) RNA processing (1.6%)" "cytoplasm (9.3%) cytosol (7.9%) nucleus (1.9%)" "metal ion binding (9.9%) translation elongation factor activity (9%) transketolase activity (7.6%)" "IPR001816 (5.2%) IPR009060 (5.2%) IPR014039 (5.2%)" "Translation elongation factor EFTs/EF1B (5.2%) UBA-like superfamily (5.2%) Translation elongation factor EFTs/EF1B, dimerisation (5.2%)" LTNKDYNENGLSELLALYGSAYNANLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.99.6 (97.3%) 3.1.1.31 (2.7%)" "glucosamine-6-phosphate deaminase (97.3%) 6-phosphogluconolactonase (2.7%)" "GO:0005975 (32.7%) GO:0006044 (32.7%)" "GO:0004342 (32.7%) GO:0016853 (1.1%) GO:0016787 (0.7%)" "carbohydrate metabolic process (32.7%) N-acetylglucosamine metabolic process (32.7%)" "glucosamine-6-phosphate deaminase activity (32.7%) isomerase activity (1.1%) hydrolase activity (0.7%)" "IPR003737 (17.1%) IPR052960 (17.1%) IPR004547 (16.4%)" "N-acetylglucosaminyl phosphatidylinositol deacetylase-related (17.1%) Glucosamine-6-phosphate deaminase-like (17.1%) Glucosamine-6-phosphate isomerase (16.4%)" DAPASLCLLCELAAWAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25.2%) GO:0006166 (25.2%)" "GO:0008973 (25.2%) GO:0000287 (24.3%)" "carbohydrate metabolic process (25.2%) purine ribonucleoside salvage (25.2%)" "phosphopentomutase activity (25.2%) magnesium ion binding (24.3%)" "IPR005846 (14.9%) IPR005844 (14.4%) IPR005845 (14.4%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.4%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.4%)" HGHEVMVQHTAGENSGFADEAYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25%) GO:0005886 (25%) "GO:0000166 (25%) GO:0000286 (25%)" L-alanine catabolic process (25%) plasma membrane (25%) "nucleotide binding (25%) alanine dehydrogenase activity (25%)" "IPR007698 (20%) IPR007886 (20%) IPR008141 (20%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20%) Alanine dehydrogenase (20%)" ASDEVEVLYEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (31.1%) IPR001179 (31.1%) IPR046357 (30.2%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (31.1%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (31.1%) Peptidyl-prolyl cis-trans isomerase domain superfamily (30.2%)" GKEVSAAQLLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (33.3%) IPR011042 (33.3%) IPR029058 (33.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (33.3%) Six-bladed beta-propeller, TolB-like (33.3%) Alpha/Beta hydrolase fold (33.3%)" GGSLLNMASVVGVHGNAGQCNYAASK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (30%) GO:0030497 (3.3%)" "GO:0004316 (30%) GO:0051287 (30%) GO:0016616 (3.3%)" "fatty acid biosynthetic process (30%) fatty acid elongation (3.3%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (30%) NAD binding (30%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (3.3%)" "IPR002347 (19%) IPR020904 (17.2%) IPR036291 (17.2%)" "Short-chain dehydrogenase/reductase SDR (19%) Short-chain dehydrogenase/reductase, conserved site (17.2%) NAD(P)-binding domain superfamily (17.2%)" LALAMLEDAEQK Bacteria Bacteria 2.5.1.47 (100%) cysteine synthase (100%) "GO:0006535 (47.2%) GO:0006534 (0.6%) GO:0009069 (0.6%)" GO:0005737 (3.8%) "GO:0004124 (46.5%) GO:0016846 (0.6%)" "cysteine biosynthetic process from serine (47.2%) cysteine metabolic process (0.6%) obsolete serine family amino acid metabolic process (0.6%)" cytoplasm (3.8%) "cysteine synthase activity (46.5%) carbon-sulfur lyase activity (0.6%)" "IPR001926 (17%) IPR050214 (17%) IPR005856 (16.6%)" "Tryptophan synthase beta chain-like, PALP domain (17%) Cysteine synthase/Cystathionine beta-synthase (17%) Cysteine synthase (16.6%)" NLGSVENYGVELAFNVKPLVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" THLVNALGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006270 (14.3%) GO:0006275 (14.3%)" "GO:0005737 (14.3%) GO:0005886 (14.3%)" "GO:0003688 (14.3%) GO:0005524 (14.3%) GO:0008289 (14.3%)" "DNA replication initiation (14.3%) regulation of DNA replication (14.3%)" "cytoplasm (14.3%) plasma membrane (14.3%)" "DNA replication origin binding (14.3%) ATP binding (14.3%) lipid binding (14.3%)" "IPR001957 (10.3%) IPR003593 (10.3%) IPR013159 (10.3%)" "Chromosomal replication control, initiator DnaA (10.3%) AAA+ ATPase domain (10.3%) Chromosomal replication initiator, DnaA C-terminal (10.3%)" GSTTQDLYQAYLELMSPLQDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (47.1%) GO:0030313 (41.2%) "GO:0016209 (5.9%) GO:0016491 (5.9%)" cytochrome complex assembly (47.1%) cell envelope (41.2%) "antioxidant activity (5.9%) oxidoreductase activity (5.9%)" "IPR025380 (21.5%) IPR013766 (20.3%) IPR050553 (20.3%)" "Domain of unknown function DUF4369 (21.5%) Thioredoxin domain (20.3%) Thioredoxin family ResA/DsbE subfamily (20.3%)" QQGQGQLQLPLSDCGVVALDYRGEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.6%) GO:0006164 (0.6%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.6%) GO:0046872 (19.6%)" "'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.6%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.6%) metal ion binding (19.6%)" "IPR055181 (11.5%) IPR010073 (11.1%) IPR010918 (11.1%)" "FGAR-AT, PurM N-terminal-like domain (11.5%) Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%)" FLDEVGYPVLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (51.4%) 6.3.4.16 (48.6%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (51.4%) carbamoyl-phosphate synthase (ammonia) (48.6%)" "GO:0006541 (14.2%) GO:0006221 (13.5%) GO:0006526 (13.5%)" GO:0005737 (14.2%) "GO:0004088 (14.2%) GO:0005524 (14.2%) GO:0046872 (14.2%)" "glutamine metabolic process (14.2%) pyrimidine nucleotide biosynthetic process (13.5%) L-arginine biosynthetic process (13.5%)" cytoplasm (14.2%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.2%) ATP binding (14.2%) metal ion binding (14.2%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" VAYSFDFGR Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) IPR010583 (100%) MltA-interacting MipA (100%) VPYMVLVGEK Bacteria Bacteria 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.4%) GO:0005737 (16.4%) "GO:0004829 (16.4%) GO:0005524 (16.4%) GO:0000049 (16.1%)" threonyl-tRNA aminoacylation (16.4%) cytoplasm (16.4%) "threonine-tRNA ligase activity (16.4%) ATP binding (16.4%) tRNA binding (16.1%)" "IPR002314 (7.8%) IPR002320 (7.8%) IPR004154 (7.8%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.8%) Threonine-tRNA ligase, class IIa (7.8%) Anticodon-binding (7.8%)" NGNGTLDDDDRYCYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" VSDEGDVEDWLASLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR032276 (100%) Protein of unknown function DUF4836 (100%) LSGAGAWCGSTAELSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR001466 (34.1%) IPR050491 (34.1%) IPR012338 (31.8%)" "Beta-lactamase-related (34.1%) Beta-lactamase AmpC-like (34.1%) Beta-lactamase/transpeptidase-like (31.8%)" MHGGVALEDLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (32.3%) GO:0006730 (1.1%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (32.3%) one-carbon metabolic process (1.1%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.1%) IPR020628 (33%) IPR027417 (33%)" "Formate-tetrahydrofolate ligase, FTHFS (34.1%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33%) P-loop containing nucleoside triphosphate hydrolase (33%)" VDLEAYNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NVNPSVGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (25%) "GO:0009279 (25%) GO:0046930 (25%)" GO:0015288 (25%) monoatomic ion transport (25%) "cell outer membrane (25%) pore complex (25%)" porin activity (25%) "IPR006664 (19.7%) IPR006665 (19.7%) IPR011250 (19.7%)" "Outer membrane protein, bacterial (19.7%) OmpA-like domain (19.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (19.7%)" RNELCDLETEAEFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.8%) IPR035994 (47.2%)" "Nucleoside phosphorylase domain (52.8%) Nucleoside phosphorylase superfamily (47.2%)" DALLAELDK root "4.3.2.2 (42%) 5.4.2.12 (24.7%) 1.1.1.85 (11.1%)" "adenylosuccinate lyase (42%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (24.7%) 3-isopropylmalate dehydrogenase (11.1%)" "GO:0017148 (5.9%) GO:0000289 (5.2%) GO:0006189 (3.3%)" "GO:0005829 (9.6%) GO:0005634 (6.1%) GO:0030015 (5.9%)" "GO:0004018 (5.4%) GO:0060090 (4.3%) GO:0004619 (3%)" "negative regulation of translation (5.9%) nuclear-transcribed mRNA poly(A) tail shortening (5.2%) 'de novo' IMP biosynthetic process (3.3%)" "cytosol (9.6%) nucleus (6.1%) CCR4-NOT core complex (5.9%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (5.4%) molecular adaptor activity (4.3%) phosphoglycerate mutase activity (3%)" "IPR027417 (4.7%) IPR003495 (3.9%) IPR011629 (3.9%)" "P-loop containing nucleoside triphosphate hydrolase (4.7%) CobW/HypB/UreG, nucleotide-binding domain (3.9%) Zinc chaperone CobW-like, C-terminal (3.9%)" NADFLVLNSTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.3%) GO:0015941 (14.3%)" GO:0071513 (14.2%) "GO:0004632 (14.3%) GO:0004633 (14.3%) GO:0010181 (14.3%)" "coenzyme A biosynthetic process (14.3%) pantothenate catabolic process (14.3%)" phosphopantothenoylcysteine decarboxylase complex (14.2%) "phosphopantothenate--cysteine ligase activity (14.3%) phosphopantothenoylcysteine decarboxylase activity (14.3%) FMN binding (14.3%)" "IPR003382 (20.3%) IPR005252 (20.3%) IPR007085 (20.3%)" "Flavoprotein (20.3%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.3%) DNA/pantothenate metabolism flavoprotein, C-terminal (20.3%)" ATPLLTELDNELSFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR034005 (20.5%) IPR045090 (20.5%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidyl-dipeptidase DCP (20.5%) Peptidase M3A/M3B (20.5%)" SKSDSLNMVLTNNLTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.97.1.12 (100%) photosystem I (100%) GO:0016020 (97.7%) GO:0016491 (2.3%) membrane (97.7%) oxidoreductase activity (2.3%) "IPR006665 (33.5%) IPR050330 (33.5%) IPR036737 (33.1%)" "OmpA-like domain (33.5%) Bacterial Outer Membrane Structural/Functional (33.5%) OmpA-like domain superfamily (33.1%)" LDFKVDK root "2.7.11.1 (25%) 2.7.13.3 (16.7%) 1.1.99.2 (8.3%)" "non-specific serine/threonine protein kinase (25%) histidine kinase (16.7%) L-2-hydroxyglutarate dehydrogenase (8.3%)" "GO:0006412 (16.2%) GO:0006417 (15.8%) GO:0006874 (0.1%)" "GO:0015934 (16.1%) GO:0016020 (0.3%) GO:0005840 (0.2%)" "GO:0003735 (16.2%) GO:0019843 (16.1%) GO:0000049 (15.8%)" "translation (16.2%) regulation of translation (15.8%) intracellular calcium ion homeostasis (0.1%)" "large ribosomal subunit (16.1%) membrane (0.3%) ribosome (0.2%)" "structural constituent of ribosome (16.2%) rRNA binding (16.1%) tRNA binding (15.8%)" "IPR028364 (15.8%) IPR023673 (15.7%) IPR023674 (15.7%)" "Ribosomal protein uL1/ribosomal biogenesis protein (15.8%) Large ribosomal subunit protein uL1, conserved site (15.7%) Ribosomal protein uL1-like (15.7%)" EQSVTFSGLTTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) GO:0045493 (50%) "GO:0004553 (43.8%) GO:0031176 (6.3%)" xylan catabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (43.8%) endo-1,4-beta-xylanase activity (6.3%)" "IPR001000 (33.3%) IPR044846 (33.3%) IPR017853 (29.2%)" "Glycoside hydrolase family 10 domain (33.3%) Glycoside hydrolase family 10 (33.3%) Glycoside hydrolase superfamily (29.2%)" YKEGNEGEYTEDENELNDWLSTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015969 (44%) GO:0005886 (44%) GO:0016787 (12%) guanosine tetraphosphate metabolic process (44%) plasma membrane (44%) hydrolase activity (12%) "IPR007685 (9.6%) IPR002912 (9.1%) IPR003607 (9.1%)" "RelA/SpoT (9.6%) ACT domain (9.1%) HD/PDEase domain (9.1%)" DEDWKPSSLFWEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (19.5%) GO:0005975 (0.5%)" GO:0005737 (20%) "GO:0003844 (20%) GO:0004553 (20%) GO:0043169 (20%)" "glycogen biosynthetic process (19.5%) carbohydrate metabolic process (0.5%)" cytoplasm (20%) "1,4-alpha-glucan branching enzyme activity (20%) hydrolase activity, hydrolyzing O-glycosyl compounds (20%) cation binding (20%)" "IPR004193 (12.7%) IPR006047 (12.7%) IPR006048 (12.7%)" "Glycoside hydrolase, family 13, N-terminal (12.7%) Glycosyl hydrolase family 13, catalytic domain (12.7%) Alpha-amylase/branching enzyme, C-terminal all beta (12.7%)" AWDGTPAYSPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (20.8%) IPR001375 (20%) IPR002469 (20%)" "WD40-like beta-propeller (20.8%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20%) Dipeptidylpeptidase IV, N-terminal domain (20%)" DYQPGAGQPDVASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.7%) IPR008969 (16.7%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (16.7%) Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%)" VETLVYNLLSNAVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (17.8%) "GO:0000155 (28.9%) GO:0003700 (26.7%) GO:0043565 (26.7%)" membrane (17.8%) "phosphorelay sensor kinase activity (28.9%) DNA-binding transcription factor activity (26.7%) sequence-specific DNA binding (26.7%)" "IPR001789 (6.7%) IPR003594 (6.7%) IPR004358 (6.7%)" "Signal transduction response regulator, receiver domain (6.7%) Histidine kinase/HSP90-like ATPase domain (6.7%) Signal transduction histidine kinase-related protein, C-terminal (6.7%)" VLSTMYAELYPLENLTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LNVMELPVLVGLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (20%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (20%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (20%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (20%)" "IPR000489 (25.2%) IPR006390 (25.2%) IPR045031 (25.2%)" "Pterin-binding domain (25.2%) Dihydropteroate synthase domain (25.2%) Dihydropteroate synthase-like (25.2%)" NFDELAPTVTQLYGTVYANVGSMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ELMGLAGSSYLELLQAQSSLLNVQLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" GNLLSCTGQLMASSLPEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071555 (25.6%) GO:0005886 (25.6%) "GO:0008658 (25.6%) GO:0004180 (23.1%)" cell wall organization (25.6%) plasma membrane (25.6%) "penicillin binding (25.6%) carboxypeptidase activity (23.1%)" "IPR005311 (17.3%) IPR050515 (17.3%) IPR001460 (16.8%)" "Penicillin-binding protein, dimerisation domain (17.3%) Class D beta-lactamase/transpeptidase (17.3%) Penicillin-binding protein, transpeptidase (16.8%)" HVLEPGDFQLMLGTNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" LNFPVKFEYTFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003959 (50%) IPR027417 (50%)" "ATPase, AAA-type, core (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" DLLWDVLGDNVLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043741 (100%) Family of unknown function DUF5686 (100%) FNLLTALSEEQPVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.10 (100%) P-type Ca(2+) transporter (100%) "GO:0005886 (20%) GO:0012505 (20%)" "GO:0005388 (20%) GO:0005524 (20%) GO:0016887 (20%)" "plasma membrane (20%) endomembrane system (20%)" "P-type calcium transporter activity (20%) ATP binding (20%) ATP hydrolysis activity (20%)" "IPR001757 (9.4%) IPR004014 (9.4%) IPR006068 (9.4%)" "P-type ATPase (9.4%) Cation-transporting P-type ATPase, N-terminal (9.4%) Cation-transporting P-type ATPase, C-terminal (9.4%)" TLAFAYK root "7.2.2.10 (51%) 3.4.21.- (42.2%) 7.6.2.1 (2.9%)" "P-type Ca(2+) transporter (51%) Serine endopeptidases (42.2%) P-type phospholipid transporter (2.9%)" "GO:0006508 (7%) GO:1902600 (1.7%) GO:0006883 (1.5%)" "GO:0005886 (13.5%) GO:0012505 (8.9%) GO:0005737 (6.8%)" "GO:0005524 (12.7%) GO:0016887 (11.6%) GO:0005388 (9.5%)" "proteolysis (7%) proton transmembrane transport (1.7%) intracellular sodium ion homeostasis (1.5%)" "plasma membrane (13.5%) endomembrane system (8.9%) cytoplasm (6.8%)" "ATP binding (12.7%) ATP hydrolysis activity (11.6%) P-type calcium transporter activity (9.5%)" "IPR023299 (6.6%) IPR023298 (6.4%) IPR036412 (6.4%)" "P-type ATPase, cytoplasmic domain N (6.6%) P-type ATPase, transmembrane domain superfamily (6.4%) HAD-like superfamily (6.4%)" YFLGWDMSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DATHSYELDFLLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (26.1%) IPR041682 (26.1%) IPR011335 (23.9%)" "Domain of unknown function DUF4143 (26.1%) AAA domain, group 14 (26.1%) Restriction endonuclease type II-like (23.9%)" NEYAFQRPYSESTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10%) IPR003593 (10%) IPR003959 (10%)" "Peptidase M41 (10%) AAA+ ATPase domain (10%) ATPase, AAA-type, core (10%)" KPAYQQEDLSSVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0046813 (50%) GO:0009279 (50%) receptor-mediated virion attachment to host cell (50%) cell outer membrane (50%) "IPR019734 (26.3%) IPR009003 (25.3%) IPR011990 (24.2%)" "Tetratricopeptide repeat (26.3%) Peptidase S1, PA clan (25.3%) Tetratricopeptide-like helical domain superfamily (24.2%)" WQSLLGLR root "1.1.1.346 (33.3%) 2.3.1.292 (33.3%) 3.1.3.48 (33.3%)" "2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (33.3%) (phenol)carboxyphthiodiolenone synthase (33.3%) protein-tyrosine-phosphatase (33.3%)" "GO:0006289 (1.5%) GO:0006633 (1.5%) GO:0019853 (1.5%)" "GO:0005737 (1.5%) GO:0009279 (1.5%) GO:0034081 (1.5%)" "GO:0005524 (37.3%) GO:0016301 (35.8%) GO:0003676 (1.5%)" "nucleotide-excision repair (1.5%) fatty acid biosynthetic process (1.5%) L-ascorbic acid biosynthetic process (1.5%)" "cytoplasm (1.5%) cell outer membrane (1.5%) polyketide synthase complex (1.5%)" "ATP binding (37.3%) kinase activity (35.8%) nucleic acid binding (1.5%)" "IPR027417 (24.3%) IPR006083 (23.3%) IPR018163 (22.3%)" "P-loop containing nucleoside triphosphate hydrolase (24.3%) Phosphoribulokinase/uridine kinase (23.3%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (22.3%)" YYLEQNGLYLGGGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR036709 (50%) IPR027385 (33.3%) IPR011250 (16.7%)" "Autotransporter beta-domain superfamily (50%) Outer membrane protein, beta-barrel domain (33.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16.7%)" SAVFLPFK root "5.6.2.4 (97.9%) 3.6.1.- (1.1%) 3.6.4.- (1.1%)" "DNA 3'-5' helicase (97.9%) In phosphorus-containing anhydrides (1.1%) Acting on ATP; involved in cellular and subcellular movement (1.1%)" "GO:0006270 (9.6%) GO:0006302 (9.6%) GO:0006310 (9.6%)" "GO:1990077 (9.5%) GO:0005737 (2.6%) GO:0035097 (0.3%)" "GO:0003677 (9.6%) GO:0005524 (9.6%) GO:0043138 (9.6%)" "DNA replication initiation (9.6%) double-strand break repair (9.6%) DNA recombination (9.6%)" "primosome complex (9.5%) cytoplasm (2.6%) histone methyltransferase complex (0.3%)" "DNA binding (9.6%) ATP binding (9.6%) 3'-5' DNA helicase activity (9.6%)" "IPR014001 (11.2%) IPR011545 (11%) IPR027417 (11%)" "Helicase superfamily 1/2, ATP-binding domain (11.2%) DEAD/DEAH-box helicase domain (11%) P-loop containing nucleoside triphosphate hydrolase (11%)" SLHFLAGYDYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (28.4%) IPR008969 (27%) IPR037066 (27%)" "TonB-dependent receptor, plug domain (28.4%) Carboxypeptidase-like, regulatory domain superfamily (27%) TonB-dependent receptor, plug domain superfamily (27%)" FLAYHLGFDGQPTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026950 (50%) IPR038636 (50%)" "Capsule assembly protein Wzi (50%) Capsule assembly protein Wzi superfamily (50%)" VTAERDPENLK Pseudomonadati Bacteria Pseudomonadati 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) "GO:0006006 (24.6%) GO:0072524 (1.8%)" "GO:0050661 (24.6%) GO:0051287 (24.6%) GO:0016620 (15.8%)" "glucose metabolic process (24.6%) pyridine-containing compound metabolic process (1.8%)" "NADP binding (24.6%) NAD binding (24.6%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (15.8%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" GLPCLLQEQNSYAGVTNK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (11.8%) GO:0030259 (11.8%) GO:0008360 (11.7%)" GO:0005886 (11.7%) "GO:0050511 (11.7%) GO:0051991 (5.9%) GO:0016758 (0.1%)" "carbohydrate metabolic process (11.8%) obsolete lipid glycosylation (11.8%) regulation of cell shape (11.7%)" plasma membrane (11.7%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.7%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (5.9%) hexosyltransferase activity (0.1%)" "IPR004276 (33.5%) IPR006009 (33.2%) IPR007235 (33.2%)" "Glycosyltransferase family 28, N-terminal domain (33.5%) N-acetylglucosaminyltransferase, MurG (33.2%) Glycosyl transferase, family 28, C-terminal (33.2%)" FAGLSDQEGEKGQSLFYLEDGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (11.1%) GO:0009279 (77.8%) GO:0015344 (11.1%) siderophore transmembrane transport (11.1%) cell outer membrane (77.8%) siderophore uptake transmembrane transporter activity (11.1%) "IPR000531 (14.3%) IPR036942 (14.3%) IPR039426 (14.3%)" "TonB-dependent receptor-like, beta-barrel (14.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.3%) TonB-dependent receptor-like (14.3%)" LLLLVNQLLDER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (5.6%) "GO:0000155 (26.8%) GO:0003700 (26.3%) GO:0043565 (26.3%)" membrane (5.6%) "phosphorelay sensor kinase activity (26.8%) DNA-binding transcription factor activity (26.3%) sequence-specific DNA binding (26.3%)" "IPR003594 (6.8%) IPR003661 (6.8%) IPR005467 (6.8%)" "Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%) Histidine kinase domain (6.8%)" LYYESNTYLEGKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001278 (12.7%) IPR001412 (12.7%) IPR008909 (12.7%)" "Arginine-tRNA ligase (12.7%) Aminoacyl-tRNA synthetase, class I, conserved site (12.7%) DALR anticodon binding (12.7%)" PAFVLSTSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (29.4%) GO:0009279 (41.2%) GO:0015344 (29.4%) siderophore transmembrane transport (29.4%) cell outer membrane (41.2%) siderophore uptake transmembrane transporter activity (29.4%) "IPR000531 (44.6%) IPR036942 (32.3%) IPR039426 (23.1%)" "TonB-dependent receptor-like, beta-barrel (44.6%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.3%) TonB-dependent receptor-like (23.1%)" FLESLGYECEKVEDVTTYPSLLGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (33.3%) IPR011607 (33.3%) IPR036914 (33.3%)" "Bifunctional purine biosynthesis protein PurH-like (33.3%) Methylglyoxal synthase-like domain (33.3%) Methylglyoxal synthase-like domain superfamily (33.3%)" LNHVYTVALLNFNMNEDAFDKEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) GYMQTPFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.8%) IPR029483 (14.8%) IPR029486 (14.8%)" "Glycosyl-hydrolase 97, catalytic domain (14.8%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.8%) Glycosyl-hydrolase 97, N-terminal domain (14.8%)" DDPQLELLNLHGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006355 (20.3%) GO:0000160 (0.8%)" "GO:0005829 (19.5%) GO:0032993 (19.5%)" "GO:0000156 (19.5%) GO:0000976 (19.5%) GO:0003677 (0.8%)" "regulation of DNA-templated transcription (20.3%) phosphorelay signal transduction system (0.8%)" "cytosol (19.5%) protein-DNA complex (19.5%)" "phosphorelay response regulator activity (19.5%) transcription cis-regulatory region binding (19.5%) DNA binding (0.8%)" "IPR001867 (19.1%) IPR001789 (18.3%) IPR036388 (18.3%)" "OmpR/PhoB-type DNA-binding domain (19.1%) Signal transduction response regulator, receiver domain (18.3%) Winged helix-like DNA-binding domain superfamily (18.3%)" SQSFSLPLLSVGNLTVGGSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (51.3%) IPR027417 (48.7%)" "Tetraacyldisaccharide 4'-kinase (51.3%) P-loop containing nucleoside triphosphate hydrolase (48.7%)" VLNLLCQAGLGADCVSGGELQAALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.9%) "GO:0008836 (33.9%) GO:0030170 (32.1%)" lysine biosynthetic process via diaminopimelate (33.9%) "diaminopimelate decarboxylase activity (33.9%) pyridoxal phosphate binding (32.1%)" "IPR002986 (14.6%) IPR022643 (14.6%) IPR022644 (14.6%)" "Diaminopimelate decarboxylase, LysA (14.6%) Orn/DAP/Arg decarboxylase 2, C-terminal (14.6%) Orn/DAP/Arg decarboxylase 2, N-terminal (14.6%)" LPKPTLLATEEFLENNLYWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006351 (25%) GO:0000428 (25%) "GO:0003677 (25%) GO:0003899 (25%)" DNA-templated transcription (25%) DNA-directed RNA polymerase complex (25%) "DNA binding (25%) DNA-directed RNA polymerase activity (25%)" IPR006110 (100%) RNA polymerase, subunit omega/Rpo6/RPB6 (100%) VQCAFVDTPELER Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0007059 (20%) GO:0051301 (20%)" GO:0005886 (20%) "GO:0003677 (20%) GO:0005524 (20%)" "chromosome segregation (20%) cell division (20%)" plasma membrane (20%) "DNA binding (20%) ATP binding (20%)" "IPR002543 (12.6%) IPR018541 (12.6%) IPR025199 (12.6%)" "FtsK domain (12.6%) FtsK gamma domain (12.6%) DNA translocase FtsK, 4TM region (12.6%)" FEDYQMVLAGAPSLDDAYYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.182 (100%) lipid-A-disaccharide synthase (100%) GO:0009245 (25%) GO:0016020 (25%) "GO:0005543 (25%) GO:0008915 (25%)" lipid A biosynthetic process (25%) membrane (25%) "phospholipid binding (25%) lipid-A-disaccharide synthase activity (25%)" IPR003835 (100%) Glycosyl transferase, family 19 (100%) SALLSAAQQEEYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.2%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.2%)" MCDDVPLVVPEVNAEDALNRPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (10.7%) GO:0009089 (10.7%) GO:0009097 (10.7%)" "GO:0046983 (11.6%) GO:0051287 (11.6%) GO:0004073 (10.7%)" "threonine biosynthetic process (10.7%) lysine biosynthetic process via diaminopimelate (10.7%) isoleucine biosynthetic process (10.7%)" "protein dimerization activity (11.6%) NAD binding (11.6%) aspartate-semialdehyde dehydrogenase activity (10.7%)" "IPR000534 (21%) IPR012280 (21%) IPR036291 (21%)" "Semialdehyde dehydrogenase, NAD-binding (21%) Semialdehyde dehydrogenase, dimerisation domain (21%) NAD(P)-binding domain superfamily (21%)" LVFCFENNPER Pseudomonadati Bacteria Pseudomonadati GO:0005886 (4.8%) "GO:0016779 (85.7%) GO:0016740 (9.5%)" plasma membrane (4.8%) "nucleotidyltransferase activity (85.7%) transferase activity (9.5%)" "IPR004821 (25.4%) IPR014729 (23.9%) IPR036554 (23.9%)" "Cytidyltransferase-like domain (25.4%) Rossmann-like alpha/beta/alpha sandwich fold (23.9%) GHMP kinase, C-terminal domain superfamily (23.9%)" GKNVTDLVLEGEGETSVLDGQGAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) GO:0005576 (33.3%) GO:0004650 (33.3%) carbohydrate metabolic process (33.3%) extracellular region (33.3%) polygalacturonase activity (33.3%) "IPR000743 (33.3%) IPR011050 (33.3%) IPR012334 (33.3%)" "Glycoside hydrolase, family 28 (33.3%) Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%)" MVNWDPK root 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20%) GO:0005829 (20%) "GO:0004832 (20.1%) GO:0005524 (20.1%) GO:0002161 (19.8%)" valyl-tRNA aminoacylation (20%) cytosol (20%) "valine-tRNA ligase activity (20.1%) ATP binding (20.1%) aminoacyl-tRNA deacylase activity (19.8%)" "IPR002300 (9.3%) IPR002303 (9.3%) IPR014729 (9.3%)" "Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%) Rossmann-like alpha/beta/alpha sandwich fold (9.3%)" KYELDSFCYPLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (52.8%) GO:0016787 (47.2%) carbohydrate metabolic process (52.8%) hydrolase activity (47.2%) "IPR008313 (33.3%) IPR008928 (33.3%) IPR012341 (33.3%)" "Metal-independent alpha-mannosidase (33.3%) Six-hairpin glycosidase superfamily (33.3%) Six-hairpin glycosidase-like superfamily (33.3%)" HYLFHGGLGALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" SNTEYQYEEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" DAKVFASADATAPEVLASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MMFGSNDLYHALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.2.29 (100%) peptidoglycan lytic transglycosylase (100%) "GO:0009252 (25%) GO:0071555 (25%)" GO:0005886 (25%) GO:0008932 (25%) "peptidoglycan biosynthetic process (25%) cell wall organization (25%)" plasma membrane (25%) lytic endotransglycosylase activity (25%) IPR003770 (100%) Endolytic murein transglycosylase (100%) WNYESPTPEQQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006281 (25%) GO:0006310 (25%)" "GO:0003676 (25%) GO:0008409 (25%)" "DNA repair (25%) DNA recombination (25%)" "nucleic acid binding (25%) 5'-3' exonuclease activity (25%)" "IPR001667 (17.4%) IPR003156 (17.4%) IPR004610 (17.4%)" "DDH domain (17.4%) DHHA1 domain (17.4%) Bacterial RecJ exonuclease (17.4%)" DLMDELALR root "4.1.1.19 (92%) 2.5.1.58 (4%) 2.5.1.59 (4%)" "arginine decarboxylase (92%) protein farnesyltransferase (4%) protein geranylgeranyltransferase type I (4%)" "GO:0006527 (19.2%) GO:0008295 (19.2%) GO:0033388 (17.6%)" "GO:0005829 (0.8%) GO:0005953 (0.8%) GO:0005965 (0.8%)" "GO:0008792 (19.2%) GO:0046872 (17.6%) GO:0004497 (2.4%)" "L-arginine catabolic process (19.2%) spermidine biosynthetic process (19.2%) putrescine biosynthetic process from arginine (17.6%)" "cytosol (0.8%) CAAX-protein geranylgeranyltransferase complex (0.8%) protein farnesyltransferase complex (0.8%)" "arginine decarboxylase activity (19.2%) metal ion binding (17.6%) monooxygenase activity (2.4%)" "IPR002985 (11.4%) IPR022644 (11.4%) IPR022653 (11.4%)" "Arginine decarboxylase (11.4%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.4%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.4%)" ASSNTYSNQVNDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32%)" LGLDLPGEK root "3.4.16.4 (92.9%) 2.4.1.129 (5.4%) 2.7.1.40 (1.8%)" "serine-type D-Ala-D-Ala carboxypeptidase (92.9%) Transferred entry: 2.4.99.28 (5.4%) pyruvate kinase (1.8%)" "GO:0071555 (14.3%) GO:0009252 (14.2%) GO:0008360 (14.1%)" GO:0005886 (14.3%) "GO:0008658 (14.3%) GO:0071972 (14.3%) GO:0009002 (12.6%)" "cell wall organization (14.3%) peptidoglycan biosynthetic process (14.2%) regulation of cell shape (14.1%)" plasma membrane (14.3%) "penicillin binding (14.3%) peptidoglycan L,D-transpeptidase activity (14.3%) serine-type D-Ala-D-Ala carboxypeptidase activity (12.6%)" "IPR001460 (16.8%) IPR050515 (16.8%) IPR005311 (16.6%)" "Penicillin-binding protein, transpeptidase (16.8%) Class D beta-lactamase/transpeptidase (16.8%) Penicillin-binding protein, dimerisation domain (16.6%)" LTGGQPVYR Pseudomonadati Bacteria Pseudomonadati "3.1.1.- (97.3%) 2.7.13.3 (2.7%)" "Carboxylic ester hydrolases (97.3%) histidine kinase (2.7%)" GO:0005886 (2.6%) "GO:0016787 (94.7%) GO:0000155 (2.6%)" plasma membrane (2.6%) "hydrolase activity (94.7%) phosphorelay sensor kinase activity (2.6%)" "IPR002018 (19.1%) IPR050309 (19.1%) IPR019819 (18.6%)" "Carboxylesterase, type B (19.1%) Type-B Carboxylesterase/Lipase (19.1%) Carboxylesterase type B, conserved site (18.6%)" KVVVSGTLLDYNGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) ESYLFAR root "3.2.1.23 (35.6%) 1.8.1.7 (32.7%) 2.1.1.319 (21.8%)" "beta-galactosidase (35.6%) glutathione-disulfide reductase (32.7%) type I protein arginine methyltransferase (21.8%)" "GO:0006749 (4.1%) GO:0034599 (4.1%) GO:0045454 (4.1%)" "GO:0016020 (10.7%) GO:0005739 (4.4%) GO:0005829 (4.2%)" "GO:0016757 (8.9%) GO:0050660 (4.2%) GO:0004362 (4.1%)" "glutathione metabolic process (4.1%) cellular response to oxidative stress (4.1%) cell redox homeostasis (4.1%)" "membrane (10.7%) mitochondrion (4.4%) cytosol (4.2%)" "glycosyltransferase activity (8.9%) flavin adenine dinucleotide binding (4.2%) glutathione-disulfide reductase (NADPH) activity (4.1%)" "IPR044174 (7%) IPR003406 (6.9%) IPR004099 (3.2%)" "Glycosyltransferase BC10-like (7%) Glycosyl transferase, family 14 (6.9%) Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain (3.2%)" DYTLSPDDWLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NVADLVLMGLKPTYPSAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.8 (100%) mannose-6-phosphate isomerase (100%) "GO:0009298 (25.9%) GO:0005976 (24.7%)" "GO:0004475 (25.9%) GO:0000166 (21%) GO:0004476 (1.2%)" "GDP-mannose biosynthetic process (25.9%) polysaccharide metabolic process (24.7%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (25.9%) nucleotide binding (21%) mannose-6-phosphate isomerase activity (1.2%)" "IPR005835 (18.1%) IPR051161 (18.1%) IPR001538 (17.2%)" "Nucleotidyl transferase domain (18.1%) Mannose-6-phosphate isomerase type 2 (18.1%) Mannose-6-phosphate isomerase, type II, C-terminal (17.2%)" SQSLLSSLNPNDLESMTLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LNLSEGKLELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR000421 (16.7%) IPR006710 (16.7%) IPR008979 (16.7%)" "Coagulation factor 5/8, C-terminal domain (16.7%) Glycoside hydrolase, family 43 (16.7%) Galactose-binding-like domain superfamily (16.7%)" GYELELHHFNHLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" VTPSDELCVSSVGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" YYELSLK root "6.5.1.4 (13.9%) 2.1.1.104 (11.1%) 2.7.11.1 (11.1%)" "RNA 3'-terminal-phosphate cyclase (ATP) (13.9%) caffeoyl-CoA O-methyltransferase (11.1%) non-specific serine/threonine protein kinase (11.1%)" "GO:0032259 (5.1%) GO:0000226 (1.2%) GO:0031175 (1.2%)" "GO:0005737 (6.9%) GO:0016020 (4.2%) GO:0005829 (3.8%)" "GO:0016887 (5.3%) GO:0000309 (4.3%) GO:0008757 (4.3%)" "methylation (5.1%) microtubule cytoskeleton organization (1.2%) neuron projection development (1.2%)" "cytoplasm (6.9%) membrane (4.2%) cytosol (3.8%)" "ATP hydrolysis activity (5.3%) nicotinamide-nucleotide adenylyltransferase activity (4.3%) S-adenosylmethionine-dependent methyltransferase activity (4.3%)" "IPR011990 (4.4%) IPR013320 (3.6%) IPR029063 (2.5%)" "Tetratricopeptide-like helical domain superfamily (4.4%) Concanavalin A-like lectin/glucanase domain superfamily (3.6%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (2.5%)" LFGLNDLNQWLAPTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.8%) "GO:0008236 (33.1%) GO:0008239 (33.1%)" proteolysis (33.8%) "serine-type peptidase activity (33.1%) dipeptidyl-peptidase activity (33.1%)" "IPR002469 (25.7%) IPR001375 (25.1%) IPR050278 (25.1%)" "Dipeptidylpeptidase IV, N-terminal domain (25.7%) Peptidase S9, prolyl oligopeptidase, catalytic domain (25.1%) Serine protease S9B/DPPIV (25.1%)" TLVPLENVGWSWLYLNHPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) HLNVNFTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" ELNLTDDANAALYYPVEPTDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR019847 (100%) Gliding motility associated protein GldN (100%) LVYQNGLYNFTGQSAEEYPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006271 (17%) "GO:0009360 (17%) GO:0005737 (14.9%)" "GO:0003677 (17%) GO:0003887 (17%) GO:0008408 (17%)" DNA strand elongation involved in DNA replication (17%) "DNA polymerase III complex (17%) cytoplasm (14.9%)" "DNA binding (17%) DNA-directed DNA polymerase activity (17%) 3'-5' exonuclease activity (17%)" "IPR001001 (20.5%) IPR022634 (20.5%) IPR022635 (20.5%)" "DNA polymerase III, beta sliding clamp (20.5%) DNA polymerase III, beta sliding clamp, N-terminal (20.5%) DNA polymerase III, beta sliding clamp, C-terminal (20.5%)" SMSDVDPEELESLTVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" KLAGTLVPVFSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.4%) IPR003385 (20.4%) IPR013783 (19.7%)" "Carbohydrate binding module family 20 (20.4%) Glycoside hydrolase, family 77 (20.4%) Immunoglobulin-like fold (19.7%)" LLEAEAVGMQPGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" VVYEGPTDSEQVLPYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.7%) GO:0016020 (0.6%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.7%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.7%) membrane (0.6%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.7%)" "IPR001264 (17.1%) IPR001460 (17.1%) IPR050396 (17.1%)" "Glycosyl transferase, family 51 (17.1%) Penicillin-binding protein, transpeptidase (17.1%) Glycosyltransferase 51/Transpeptidase (17.1%)" EASFSVGNLYLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.4%) IPR004659 (25.4%) IPR019307 (25.4%)" "S1 domain (25.4%) Ribonuclease E/G (25.4%) RNA-binding protein AU-1/Ribonuclease E/G (25.4%)" DFEGSDLLVADGQTVTYGSPTLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (36.4%) IPR011493 (33.1%) IPR042278 (30.1%)" "Fimbrillin-like 1 (36.4%) GLUG (33.1%) Fimbrillin-like 1, N-terminal (30.1%)" LFGMTAGLPVTLEGLVGANGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.1 (100%) transketolase (100%) GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005474 (12.5%) IPR005475 (12.5%) IPR009014 (12.5%)" "Transketolase, N-terminal (12.5%) Transketolase-like, pyrimidine-binding domain (12.5%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.5%)" RLQVVEGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) GO:0000428 (16.9%) "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (15.9%)" DNA-templated transcription (16.9%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (15.9%)" "IPR006592 (9.3%) IPR007080 (9.3%) IPR045867 (9.3%)" "RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 1 (9.3%) DNA-directed RNA polymerase, subunit beta-prime (9.3%)" LTSTLDLVK root "IPR024480 (48.6%) IPR036737 (48.6%) IPR001660 (1.4%)" "Domain of unknown function DUF3868 (48.6%) OmpA-like domain superfamily (48.6%) Sterile alpha motif domain (1.4%)" LFPDFVEEFNALLKPEER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) NQSLSSGSQCLGLNAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026950 (50.9%) IPR038636 (49.1%)" "Capsule assembly protein Wzi (50.9%) Capsule assembly protein Wzi superfamily (49.1%)" WNDSSCYSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011250 (50%) IPR027385 (50%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (50%) Outer membrane protein, beta-barrel domain (50%)" ELLAELLK root "2.4.1.17 (61.4%) 7.4.2.8 (6.3%) 3.2.1.21 (5.5%)" "glucuronosyltransferase (61.4%) protein-secreting ATPase (6.3%) beta-glucosidase (5.5%)" "GO:0006302 (1.1%) GO:0006605 (0.7%) GO:0017038 (0.7%)" "GO:0005789 (6.5%) GO:0030430 (5.9%) GO:0044423 (5.9%)" "GO:0015020 (5.9%) GO:0003968 (5.9%) GO:0008270 (4.3%)" "double-strand break repair (1.1%) protein targeting (0.7%) protein import (0.7%)" "endoplasmic reticulum membrane (6.5%) host cell cytoplasm (5.9%) virion component (5.9%)" "glucuronosyltransferase activity (5.9%) RNA-directed RNA polymerase activity (5.9%) zinc ion binding (4.3%)" "IPR002213 (6%) IPR050271 (6%) IPR003487 (5.3%)" "UDP-glucuronosyl/UDP-glucosyltransferase (6%) UDP-glycosyltransferase (6%) Phosphoprotein, pneumoviral (5.3%)" VKNLTLGYTLPK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (3.4%) GO:0009279 (96.6%) iron ion transport (3.4%) cell outer membrane (96.6%) "IPR023996 (12.9%) IPR012910 (12.7%) IPR023997 (12.7%)" "TonB-dependent outer membrane protein, SusC/RagA (12.9%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" YLSPFQFGTLATNENFLDRQEDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR027417 (67.9%) IPR011579 (32.1%)" "P-loop containing nucleoside triphosphate hydrolase (67.9%) ATPase domain (32.1%)" EVWNEDVKGEDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0051920 (100%) peroxiredoxin activity (100%) "IPR003779 (21.4%) IPR047263 (21.4%) IPR011051 (19%)" "Carboxymuconolactone decarboxylase-like (21.4%) Hydroxynitrile lyase-like, cupin domain (21.4%) RmlC-like cupin domain superfamily (19%)" MGSYHVSVLGEVEKPGLLYAPQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (47.1%) GO:0015159 (52.9%) membrane (47.1%) polysaccharide transmembrane transporter activity (52.9%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" LYLYLLR root "3.2.2.- (9.3%) 2.7.1.25 (6.7%) 1.8.3.2 (5.3%)" "Hydrolyzing N-glycosyl compounds (9.3%) adenylyl-sulfate kinase (6.7%) thiol oxidase (5.3%)" "GO:0015920 (8.3%) GO:0015774 (6.9%) GO:0007129 (2.7%)" "GO:0005886 (9.7%) GO:0016020 (6.8%) GO:0005634 (3.8%)" "GO:0140359 (6.9%) GO:0070182 (2.7%) GO:0005524 (1.6%)" "lipopolysaccharide transport (8.3%) polysaccharide transport (6.9%) homologous chromosome pairing at meiosis (2.7%)" "plasma membrane (9.7%) membrane (6.8%) nucleus (3.8%)" "ABC-type transporter activity (6.9%) DNA polymerase binding (2.7%) ATP binding (1.6%)" "IPR013525 (9.2%) IPR029448 (4.4%) IPR006343 (2.9%)" "ABC-2 type transporter, transmembrane domain (9.2%) Fanconi anaemia protein FANCD2 (4.4%) DnaB/C, C-terminal domain (2.9%)" DAASAALYGSQSANGVVLLTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (29.3%) GO:0009279 (41.5%) GO:0015344 (29.3%) siderophore transmembrane transport (29.3%) cell outer membrane (41.5%) siderophore uptake transmembrane transporter activity (29.3%) "IPR012910 (13.9%) IPR023996 (13.9%) IPR023997 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent outer membrane protein, SusC/RagA (13.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.9%)" RADMYADFFSNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" RSASLLDASQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" YLSLLTDFGFKR Bacteria Bacteria GO:0071973 (25%) "GO:0009288 (25%) GO:0016020 (25%)" GO:0003774 (25%) bacterial-type flagellum-dependent cell motility (25%) "bacterial-type flagellum (25%) membrane (25%)" cytoskeletal motor activity (25%) "IPR010106 (97.6%) IPR025587 (1.8%) IPR000563 (0.6%)" "Recombination-promoting nuclease RpnA (97.6%) Domain of unknown function DUF4351 (1.8%) Flagellar assembly protein FliH (0.6%)" NDATTAHANFATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LLPLVLDAK root "4.2.1.33 (46.2%) 4.2.1.3 (15.4%) 6.3.2.4 (15.4%)" "3-isopropylmalate dehydratase (46.2%) aconitate hydratase (15.4%) D-alanine--D-alanine ligase (15.4%)" "GO:0009098 (3.1%) GO:0008360 (1.5%) GO:0009252 (1.5%)" "GO:0016020 (16.8%) GO:0009316 (3.1%) GO:0005737 (2.3%)" "GO:0000155 (17.6%) GO:0003700 (16.8%) GO:0043565 (16.8%)" "L-leucine biosynthetic process (3.1%) regulation of cell shape (1.5%) peptidoglycan biosynthetic process (1.5%)" "membrane (16.8%) 3-isopropylmalate dehydratase complex (3.1%) cytoplasm (2.3%)" "phosphorelay sensor kinase activity (17.6%) DNA-binding transcription factor activity (16.8%) sequence-specific DNA binding (16.8%)" "IPR011110 (9.9%) IPR015943 (9.5%) IPR011123 (9.1%)" "Two component regulator propeller (9.9%) WD40/YVTN repeat-like-containing domain superfamily (9.5%) Two component regulator three Y (9.1%)" ALLNDMGFLENELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25.4%) IPR005263 (25.4%) IPR020625 (25.4%)" "DapA-like (25.4%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25.4%) Schiff base-forming aldolase, active site (25.4%)" LVSLAQVSNVLGTVNPVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.8.1.7 (100%) cysteine desulfurase (100%) GO:0006534 (33.3%) "GO:0030170 (33.3%) GO:0031071 (33.3%)" cysteine metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) cysteine desulfurase activity (33.3%)" "IPR000192 (14.3%) IPR010970 (14.3%) IPR015421 (14.3%)" "Aminotransferase class V domain (14.3%) Cysteine desulfurase, SufS (14.3%) Pyridoxal phosphate-dependent transferase, major domain (14.3%)" QYLQDNQVSLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (25%) GO:0005737 (25%) "GO:0046872 (25%) GO:0070006 (25%)" proteolysis (25%) cytoplasm (25%) "metal ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000587 (12.8%) IPR000994 (12.8%) IPR001131 (12.8%)" "Creatinase, N-terminal (12.8%) Peptidase M24 (12.8%) Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site (12.8%)" LPAYTNLK root 3.5.1.25 (100%) N-acetylglucosamine-6-phosphate deacetylase (100%) "GO:0006046 (3.6%) GO:0019262 (3.6%) GO:0106279 (3.6%)" "GO:0009279 (67.9%) GO:0005774 (7.1%) GO:0016020 (3.6%)" "GO:0015179 (7.1%) GO:0008448 (3.6%)" "N-acetylglucosamine catabolic process (3.6%) N-acetylneuraminate catabolic process (3.6%) negative regulation of UDP-N-acetylglucosamine biosynthetic process (3.6%)" "cell outer membrane (67.9%) vacuolar membrane (7.1%) membrane (3.6%)" "L-amino acid transmembrane transporter activity (7.1%) N-acetylglucosamine-6-phosphate deacetylase activity (3.6%)" "IPR011990 (31.3%) IPR033985 (29.9%) IPR012944 (28.4%)" "Tetratricopeptide-like helical domain superfamily (31.3%) SusD-like, N-terminal (29.9%) RagB/SusD domain (28.4%)" YLFTATFR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (6.2%) GO:0005975 (1%) GO:0044718 (1%)" GO:0009279 (89.7%) "GO:0004553 (1%) GO:0015344 (1%)" "iron ion transport (6.2%) carbohydrate metabolic process (1%) siderophore transmembrane transport (1%)" cell outer membrane (89.7%) "hydrolase activity, hydrolyzing O-glycosyl compounds (1%) siderophore uptake transmembrane transporter activity (1%)" "IPR039426 (12.9%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like (12.9%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" EGDTLDFYSNL Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (20.1%) "GO:0005840 (20.1%) GO:1990904 (20%) GO:0022625 (0.1%)" "GO:0003735 (20.1%) GO:0019843 (19.6%)" translation (20.1%) "ribosome (20.1%) ribonucleoprotein complex (20%) cytosolic large ribosomal subunit (0.1%)" "structural constituent of ribosome (20.1%) rRNA binding (19.6%)" "IPR012677 (33.3%) IPR012678 (33.3%) IPR013025 (33.3%)" "Nucleotide-binding alpha-beta plait domain superfamily (33.3%) Ribosomal protein uL23/eL15/eS24 core domain superfamily (33.3%) Large ribosomal subunit protein uL23-like (33.3%)" VDLLAGLLTYSSDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" VLPCFMFLLPGMLAAALAQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (52.8%) IPR038377 (47.2%)" "Sodium/solute symporter (52.8%) Sodium/glucose symporter superfamily (47.2%)" EPEATLTHWLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) "GO:0001522 (23.3%) GO:0006396 (16.3%)" "GO:0003723 (23.3%) GO:0009982 (20.9%) GO:0140098 (14%)" "pseudouridine synthesis (23.3%) RNA processing (16.3%)" "RNA binding (23.3%) pseudouridine synthase activity (20.9%) catalytic activity, acting on RNA (14%)" "IPR006145 (26.3%) IPR006224 (26.3%) IPR050188 (26.3%)" "Pseudouridine synthase, RsuA/RluA-like (26.3%) Pseudouridine synthase, RluA-like, conserved site (26.3%) RluA Pseudouridine Synthase (26.3%)" WNNSSLADDYQTAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005975 (50%) "GO:0004553 (30%) GO:0004565 (20%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (30%) beta-galactosidase activity (20%)" "IPR001944 (14.3%) IPR008979 (14.3%) IPR017853 (14.3%)" "Glycoside hydrolase, family 35 (14.3%) Galactose-binding-like domain superfamily (14.3%) Glycoside hydrolase superfamily (14.3%)" LPYDLNFSVEGLYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (32%) GO:0009279 (36%) GO:0015344 (32%) siderophore transmembrane transport (32%) cell outer membrane (36%) siderophore uptake transmembrane transporter activity (32%) "IPR057601 (24.3%) IPR036942 (21.6%) IPR039426 (21.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (24.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (21.6%) TonB-dependent receptor-like (21.6%)" FLELVEAR root "3.7.1.3 (95.3%) 2.7.13.3 (2.8%) 2.5.1.74 (0.9%)" "kynureninase (95.3%) histidine kinase (2.8%) 1,4-dihydroxy-2-naphthoate polyprenyltransferase (0.9%)" "GO:0009435 (9.3%) GO:0019441 (9.3%) GO:0019805 (9.3%)" "GO:0005737 (9.4%) GO:0009898 (5.5%) GO:0032153 (5.5%)" "GO:0030170 (9.3%) GO:0030429 (9.3%) GO:0016811 (1.3%)" "NAD+ biosynthetic process (9.3%) L-tryptophan catabolic process to kynurenine (9.3%) quinolinate biosynthetic process (9.3%)" "cytoplasm (9.4%) cytoplasmic side of plasma membrane (5.5%) cell division site (5.5%)" "pyridoxal phosphate binding (9.3%) kynureninase activity (9.3%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (1.3%)" "IPR010111 (12.7%) IPR015421 (12.7%) IPR015422 (12.7%)" "Kynureninase (12.7%) Pyridoxal phosphate-dependent transferase, major domain (12.7%) Pyridoxal phosphate-dependent transferase, small domain (12.7%)" PTSLSFEDVWKER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" LNSADLTDKGTDWLAK Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" GSGNYGFMDQVAALQWVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.1%) IPR019819 (20.1%) IPR019826 (20.1%)" "Carboxylesterase, type B (20.1%) Carboxylesterase type B, conserved site (20.1%) Carboxylesterase type B, active site (20.1%)" LVFFTNLSHELR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19.4%) "GO:0000155 (20.9%) GO:0003700 (20.4%) GO:0043565 (20.4%)" membrane (19.4%) "phosphorelay sensor kinase activity (20.9%) DNA-binding transcription factor activity (20.4%) sequence-specific DNA binding (20.4%)" "IPR003594 (7.9%) IPR003661 (7.9%) IPR001789 (7.7%)" "Histidine kinase/HSP90-like ATPase domain (7.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.9%) Signal transduction response regulator, receiver domain (7.7%)" SSLLFTDQLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.26.- (100%) Endoribonucleases producing 5'-phosphomonoesters (100%) GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR004659 (25.3%) IPR019307 (25.3%) IPR003029 (24.7%)" "Ribonuclease E/G (25.3%) RNA-binding protein AU-1/Ribonuclease E/G (25.3%) S1 domain (24.7%)" SPLTLLMGPLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (3.2%) "GO:0000155 (27.1%) GO:0003700 (26.5%) GO:0043565 (26.5%)" membrane (3.2%) "phosphorelay sensor kinase activity (27.1%) DNA-binding transcription factor activity (26.5%) sequence-specific DNA binding (26.5%)" "IPR003594 (6.9%) IPR003661 (6.9%) IPR005467 (6.9%)" "Histidine kinase/HSP90-like ATPase domain (6.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.9%) Histidine kinase domain (6.9%)" DNSDKTYLVNTLSGVGSFLTSELPTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) YGDNDTNLGFLLTDSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.8%) "GO:0005524 (20.3%) GO:0016881 (20.3%) GO:0008784 (19.8%)" D-alanine biosynthetic process (19.8%) "ATP binding (20.3%) acid-amino acid ligase activity (20.3%) alanine racemase activity (19.8%)" "IPR013221 (10.4%) IPR051046 (10.4%) IPR000821 (10.1%)" "Mur ligase, central (10.4%) MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.4%) Alanine racemase (10.1%)" VHEVVDYCLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (21.4%) IPR024361 (21.4%) IPR050386 (21.4%)" "Glycoside hydrolase, family 5 (21.4%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.4%) Glycosyl Hydrolase 5 (Cellulase A) (21.4%)" NKDAEVTVDMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LDAQLVR root "1.4.1.13 (20.7%) 2.10.1.1 (10.6%) 2.7.1.35 (10.2%)" "glutamate synthase (NADPH) (20.7%) molybdopterin molybdotransferase (10.6%) pyridoxal kinase (10.2%)" "GO:0007165 (2.6%) GO:0052131 (2.4%) GO:0006537 (1.6%)" "GO:0005829 (6.8%) GO:0005886 (5.1%) GO:0016020 (4.9%)" "GO:0046872 (4%) GO:0005524 (2.7%) GO:0000976 (2.6%)" "signal transduction (2.6%) positive aerotaxis (2.4%) glutamate biosynthetic process (1.6%)" "cytosol (6.8%) plasma membrane (5.1%) membrane (4.9%)" "metal ion binding (4%) ATP binding (2.7%) transcription cis-regulatory region binding (2.6%)" "IPR027417 (3.7%) IPR003495 (2.9%) IPR051927 (2.9%)" "P-loop containing nucleoside triphosphate hydrolase (3.7%) CobW/HypB/UreG, nucleotide-binding domain (2.9%) Zinc Chaperone and cDPG Synthetase (2.9%)" KYDLYLFSDEVYR Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.6.1.1 (59.5%) 2.6.1.- (40.5%)" "aspartate transaminase (59.5%) Transaminases (40.5%)" GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (29%) GO:0004069 (4.3%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (29%) L-aspartate:2-oxoglutarate aminotransferase activity (4.3%)" "IPR004839 (20.1%) IPR050596 (20.1%) IPR015421 (19.8%)" "Aminotransferase, class I/classII, large domain (20.1%) Aspartate/prephenate aminotransferase-like (20.1%) Pyridoxal phosphate-dependent transferase, major domain (19.8%)" EDNGWQPDFDALEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.- (100%) Transaminases (100%) "GO:0008483 (50%) GO:0030170 (50%)" "transaminase activity (50%) pyridoxal phosphate binding (50%)" "IPR004838 (17.6%) IPR004839 (17.6%) IPR050881 (17.6%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (17.6%) Aminotransferase, class I/classII, large domain (17.6%) LL-diaminopimelate aminotransferase (17.6%)" KYSTMTYDELDVVEDLLEPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR000595 (33.3%) IPR014710 (33.3%) IPR018490 (33.3%)" "Cyclic nucleotide-binding domain (33.3%) RmlC-like jelly roll fold (33.3%) Cyclic nucleotide-binding domain superfamily (33.3%)" NLVDSTGLLDEEVLDKLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EFLSLLK root "3.5.4.16 (42.9%) 2.7.10.2 (9.5%) 2.7.6.5 (6.1%)" "GTP cyclohydrolase I (42.9%) non-specific protein-tyrosine kinase (9.5%) GTP diphosphokinase (6.1%)" "GO:0046654 (4%) GO:0006729 (4%) GO:0006730 (3.4%)" "GO:0005737 (6.4%) GO:0043190 (2.9%) GO:0005634 (2.3%)" "GO:0008270 (4.4%) GO:0005525 (4.1%) GO:0003934 (4%)" "tetrahydrofolate biosynthetic process (4%) tetrahydrobiopterin biosynthetic process (4%) one-carbon metabolic process (3.4%)" "cytoplasm (6.4%) ATP-binding cassette (ABC) transporter complex (2.9%) nucleus (2.3%)" "zinc ion binding (4.4%) GTP binding (4.1%) GTP cyclohydrolase I activity (4%)" "IPR020602 (3.4%) IPR001474 (3.4%) IPR043133 (3.4%)" "GTP cyclohydrolase I domain (3.4%) GTP cyclohydrolase I (3.4%) GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase (3.4%)" ELMVYVYR Pseudomonadati Bacteria Pseudomonadati 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (21.4%) GO:0044208 (21.4%) GO:0006188 (8.9%)" GO:0016020 (0.9%) "GO:0004018 (30.4%) GO:0070626 (14.3%) GO:0004016 (0.9%)" "'de novo' IMP biosynthetic process (21.4%) 'de novo' AMP biosynthetic process (21.4%) IMP biosynthetic process (8.9%)" membrane (0.9%) "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (30.4%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (14.3%) adenylate cyclase activity (0.9%)" "IPR000362 (12.3%) IPR004769 (12.3%) IPR008948 (12.3%)" "Fumarate lyase family (12.3%) Adenylosuccinate lyase (12.3%) L-Aspartase-like (12.3%)" NEGVNALYEALDDMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006526 (34%) "GO:0008777 (34%) GO:0046872 (32.1%)" L-arginine biosynthetic process (34%) "acetylornithine deacetylase activity (34%) metal ion binding (32.1%)" "IPR001261 (20.2%) IPR002933 (20.2%) IPR011650 (20.2%)" "ArgE/DapE/ACY1/CPG2/YscS, conserved site (20.2%) Peptidase M20 (20.2%) Peptidase M20, dimerisation domain (20.2%)" WTYTVGTELPTGVLFTHDGGQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR031965 (50%)" "Immunoglobulin-like fold (50%) Starch-binding module 26 (50%)" NLYTYLYAGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" RLLDLYSSTAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%) GO:0015935 (0.1%)" "GO:0003735 (20%) GO:0000049 (18.7%) GO:0003723 (1.2%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%) small ribosomal subunit (0.1%)" "structural constituent of ribosome (20%) tRNA binding (18.7%) RNA binding (1.2%)" "IPR001848 (25.1%) IPR027486 (25.1%) IPR036838 (25.1%)" "Small ribosomal subunit protein uS10 (25.1%) Small ribosomal subunit protein uS10 domain (25.1%) Small ribosomal subunit protein uS10 domain superfamily (25.1%)" TTLYGAFENLLDELKDDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.9 (100%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (100%) GO:0009234 (20.3%) "GO:0030976 (20.3%) GO:0070204 (20.3%) GO:0000287 (19.5%)" menaquinone biosynthetic process (20.3%) "thiamine pyrophosphate binding (20.3%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (20.3%) magnesium ion binding (19.5%)" "IPR004433 (25.7%) IPR012001 (25.7%) IPR011766 (24.8%)" "2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (25.7%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (25.7%) Thiamine pyrophosphate enzyme, TPP-binding (24.8%)" VHSEGLANQLQALAEWSYSLDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (20.8%) IPR006710 (20%) IPR013320 (20%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (20.8%) Glycoside hydrolase, family 43 (20%) Concanavalin A-like lectin/glucanase domain superfamily (20%)" VNGPHQGAWVDTQNGEDWFLHFQDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" ETGMVPVFFNKDVELCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (55.6%) GO:0008675 (22.2%) GO:0008700 (22.2%)" "lyase activity (55.6%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (22.2%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (22.2%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" SFTPLYQFSLYSYNTANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" LGYHVDYYPVSSLMEYYKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.5%) GO:0005829 (25.5%) "GO:0008733 (25.5%) GO:0030145 (23.4%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.5%) cytosol (25.5%) "L-arabinose isomerase activity (25.5%) manganese ion binding (23.4%)" "IPR003762 (15.2%) IPR024664 (15.2%) IPR055390 (15.2%)" "L-arabinose isomerase (15.2%) L-arabinose isomerase, C-terminal (15.2%) L-arabinose isomerase, central domain (15.2%)" NHDYDEAWR Bacteroidota Bacteria Pseudomonadati Bacteroidota IPR011630 (100%) Nucleotide modification associated domain 1 (100%) MNFPTLLPHQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (6.7%) IPR006101 (6.7%) IPR006102 (6.7%)" "Beta galactosidase small chain/ domain 5 (6.7%) Glycoside hydrolase, family 2 (6.7%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.7%)" YADALLMK root "GO:0006935 (0.6%) GO:0007165 (0.6%)" "GO:0009279 (96.2%) GO:0016020 (0.6%)" "GO:0003676 (0.6%) GO:0004888 (0.6%) GO:0008253 (0.6%)" "chemotaxis (0.6%) signal transduction (0.6%)" "cell outer membrane (96.2%) membrane (0.6%)" "nucleic acid binding (0.6%) transmembrane signaling receptor activity (0.6%) 5'-nucleotidase activity (0.6%)" "IPR012944 (33.6%) IPR011990 (32.9%) IPR033985 (32.2%)" "RagB/SusD domain (33.6%) Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (32.2%)" FALCTVAK root 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (15.2%) GO:0006164 (8.8%) GO:0006189 (6.4%)" "GO:0005576 (3.9%) GO:0005634 (3.9%) GO:0016020 (3.9%)" "GO:0004044 (15.2%) GO:0046872 (15.2%) GO:0051536 (15.2%)" "purine nucleobase biosynthetic process (15.2%) purine nucleotide biosynthetic process (8.8%) 'de novo' IMP biosynthetic process (6.4%)" "extracellular region (3.9%) nucleus (3.9%) membrane (3.9%)" "amidophosphoribosyltransferase activity (15.2%) metal ion binding (15.2%) iron-sulfur cluster binding (15.2%)" "IPR017932 (13%) IPR000836 (12.6%) IPR029055 (12.3%)" "Glutamine amidotransferase type 2 domain (13%) Phosphoribosyltransferase domain (12.6%) Nucleophile aminohydrolases, N-terminal (12.3%)" VEGDELEEGMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.7 (100%) altronate dehydratase (100%) GO:0019698 (49.3%) "GO:0016829 (47.8%) GO:0008789 (1.5%) GO:0016787 (1.5%)" D-galacturonate catabolic process (49.3%) "lyase activity (47.8%) altronate dehydratase activity (1.5%) hydrolase activity (1.5%)" "IPR007392 (20%) IPR013974 (20%) IPR044144 (20%)" "D-galactarate/Altronate dehydratase, second domain (20%) SAF domain (20%) UxaA/GarD, SAF domain (20%)" KVALNDAVFGLEPNDHVLYLDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" GLTDNDVANGTQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.2%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.2%)" "IPR004199 (6.8%) IPR006102 (6.8%) IPR006103 (6.8%)" "Beta galactosidase small chain/ domain 5 (6.8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.8%) Glycoside hydrolase family 2, catalytic domain (6.8%)" EATGTYFQDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0052689 (50%) cell outer membrane (50%) carboxylic ester hydrolase activity (50%) "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" VNLTPGVSENLTLGEGMNFGDTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (68.8%) "GO:0016787 (21.9%) GO:0016829 (9.4%)" carbohydrate metabolic process (68.8%) "hydrolase activity (21.9%) lyase activity (9.4%)" "IPR006047 (24.2%) IPR013783 (24.2%) IPR017853 (24.2%)" "Glycosyl hydrolase family 13, catalytic domain (24.2%) Immunoglobulin-like fold (24.2%) Glycoside hydrolase superfamily (24.2%)" QLNTYDWLADVPGNAESTDLVEVQFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" TGAVTDLDGNFTLEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (27.9%) GO:0009279 (44.2%) GO:0015344 (27.9%) siderophore transmembrane transport (27.9%) cell outer membrane (44.2%) siderophore uptake transmembrane transporter activity (27.9%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" ESDDKYLSVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" TLVEHAEGLTEEAFTNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" TVVGYEYYASDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.4%) IPR012910 (13.4%) IPR023996 (13.4%)" "TonB-dependent receptor-like, beta-barrel (13.4%) TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%)" VQEELGEDWNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.9 (100%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (100%) GO:0009234 (20.3%) "GO:0030976 (20.3%) GO:0070204 (20.3%) GO:0000287 (19.6%)" menaquinone biosynthetic process (20.3%) "thiamine pyrophosphate binding (20.3%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (20.3%) magnesium ion binding (19.6%)" "IPR004433 (25.6%) IPR012001 (25.6%) IPR011766 (24.8%)" "2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (25.6%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (25.6%) Thiamine pyrophosphate enzyme, TPP-binding (24.8%)" AACCNLGESFTTNPSVDVAYNDATTGAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" PFVLTDEELAGLEGLETQDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002880 (7.9%) IPR011766 (7.9%) IPR011895 (7.9%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.9%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Pyruvate-flavodoxin oxidoreductase (7.9%)" KVALEFHSYSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (32.7%) "GO:0030170 (33.7%) GO:0010285 (32.7%) GO:0008483 (1%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (32.7%) "pyridoxal phosphate binding (33.7%) L,L-diaminopimelate aminotransferase activity (32.7%) transaminase activity (1%)" "IPR004839 (20.9%) IPR019942 (20.9%) IPR015421 (19.6%)" "Aminotransferase, class I/classII, large domain (20.9%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (20.9%) Pyridoxal phosphate-dependent transferase, major domain (19.6%)" FLVSWLK root "2.1.1.72 (19.2%) 2.7.11.1 (19.2%) 2.5.1.18 (11.5%)" "site-specific DNA-methyltransferase (adenine-specific) (19.2%) non-specific serine/threonine protein kinase (19.2%) glutathione transferase (11.5%)" "GO:0006661 (3.4%) GO:0009307 (1.9%) GO:0032259 (1.9%)" "GO:0016020 (6.1%) GO:0005829 (4.6%) GO:0010008 (3.4%)" "GO:0016746 (9.1%) GO:0005524 (4.9%) GO:0008270 (3%)" "phosphatidylinositol biosynthetic process (3.4%) DNA restriction-modification system (1.9%) methylation (1.9%)" "membrane (6.1%) cytosol (4.6%) endosome membrane (3.4%)" "acyltransferase activity (9.1%) ATP binding (4.9%) zinc ion binding (3%)" "IPR045746 (8.2%) IPR001810 (4.4%) IPR036047 (3.8%)" "Putative acyltransferase ACT14924-like, acyltransferase domain (8.2%) F-box domain (4.4%) F-box-like domain superfamily (3.8%)" GLFLNDEAPCLTSWVK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "GO:0005975 (36.3%) GO:0045493 (12.7%)" "GO:0016787 (38.2%) GO:0046559 (12.7%)" "carbohydrate metabolic process (36.3%) xylan catabolic process (12.7%)" "hydrolase activity (38.2%) alpha-glucuronidase activity (12.7%)" "IPR031924 (24.2%) IPR041437 (24.2%) IPR029018 (22.8%)" "Glycosyl hydrolase family 115 (24.2%) Gylcosyl hydrolase 115 C-terminal domain (24.2%) Beta-hexosaminidase-like, domain 2 (22.8%)" TYTLSLK root "3.6.4.- (21.1%) 4.6.1.13 (19.3%) 3.4.11.2 (12.3%)" "Acting on ATP; involved in cellular and subcellular movement (21.1%) phosphatidylinositol diacylglycerol-lyase (19.3%) membrane alanyl aminopeptidase (12.3%)" "GO:0016192 (1.4%) GO:0030036 (1.4%) GO:0098609 (1.4%)" "GO:0016020 (6.6%) GO:0005886 (4.8%) GO:0009279 (4.2%)" "GO:0005524 (5.2%) GO:0016787 (3.9%) GO:0015159 (3.3%)" "vesicle-mediated transport (1.4%) actin cytoskeleton organization (1.4%) cell-cell adhesion (1.4%)" "membrane (6.6%) plasma membrane (4.8%) cell outer membrane (4.2%)" "ATP binding (5.2%) hydrolase activity (3.9%) polysaccharide transmembrane transporter activity (3.3%)" "IPR013783 (4%) IPR027417 (2.4%) IPR008969 (1.9%)" "Immunoglobulin-like fold (4%) P-loop containing nucleoside triphosphate hydrolase (2.4%) Carboxypeptidase-like, regulatory domain superfamily (1.9%)" AWQVYVEPSMNWFLHDNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.6%) "GO:0009279 (26.3%) GO:0046930 (24.6%)" GO:0015288 (24.6%) monoatomic ion transport (24.6%) "cell outer membrane (26.3%) pore complex (24.6%)" porin activity (24.6%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" WNTDFNLSFNK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (4.9%) GO:0044718 (2.4%)" GO:0009279 (90.2%) GO:0015344 (2.4%) "iron ion transport (4.9%) siderophore transmembrane transport (2.4%)" cell outer membrane (90.2%) siderophore uptake transmembrane transporter activity (2.4%) "IPR012910 (12.7%) IPR023996 (12.7%) IPR023997 (12.7%)" "TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" HLYETLPSTDCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" NYVSQEELEDAPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" CGWCDLVQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" AALYSEKDEYEGCMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015012 (24.7%) GO:0050650 (24.7%)" "GO:0016020 (23.6%) GO:0000139 (1.1%) GO:0005789 (1.1%)" GO:0030158 (24.7%) "heparan sulfate proteoglycan biosynthetic process (24.7%) chondroitin sulfate proteoglycan biosynthetic process (24.7%)" "membrane (23.6%) Golgi membrane (1.1%) endoplasmic reticulum membrane (1.1%)" protein xylosyltransferase activity (24.7%) "IPR003406 (50%) IPR043538 (50%)" "Glycosyl transferase, family 14 (50%) Xylosyltransferase (50%)" YGANYTAGAPYWLTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EYLKDYEALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (80%) GO:0005737 (10%) GO:0005886 (10%)" "extracellular space (80%) cytoplasm (10%) plasma membrane (10%)" "IPR001611 (16.2%) IPR027899 (16.2%) IPR041403 (16.2%)" "Leucine-rich repeat (16.2%) Domain of unknown function DUF4458 (16.2%) DUF4458 domain-containing protein, leucine-rich repeat (16.2%)" HLEYAKDQCDLALYPESYFQDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32%)" FTHGNLYGLLGANGAGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.1%) IPR003593 (20.1%) IPR032781 (20.1%)" "ABC transporter-like, ATP-binding domain (20.1%) AAA+ ATPase domain (20.1%) ABC-transporter extension domain (20.1%)" ELNEWVAAGNGVLQGSSVKPGDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.6%) IPR012910 (13.6%) IPR023996 (13.6%)" "TonB-dependent receptor-like, beta-barrel (13.6%) TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%)" TANFGLLYGLTTFGLAQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006261 (16.7%) GO:0006302 (16.7%)" "GO:0003677 (16.7%) GO:0003887 (16.7%) GO:0008408 (16.7%)" "DNA-templated DNA replication (16.7%) double-strand break repair (16.7%)" "DNA binding (16.7%) DNA-directed DNA polymerase activity (16.7%) 3'-5' exonuclease activity (16.7%)" "IPR001098 (7.8%) IPR002298 (7.8%) IPR002421 (7.8%)" "DNA-directed DNA polymerase, family A, palm domain (7.8%) DNA polymerase A (7.8%) 5'-3' exonuclease (7.8%)" TFEEGNEPVAKPAHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.5%) IPR012340 (24.5%) IPR035104 (24.5%)" "S1 domain (24.5%) Nucleic acid-binding, OB-fold (24.5%) Ribosomal protein S1-like (24.5%)" LYALNNHHLLELLHDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006355 (46.2%) GO:0043200 (3.8%)" GO:0005829 (3.8%) GO:0043565 (46.2%) "regulation of DNA-templated transcription (46.2%) response to amino acid (3.8%)" cytosol (3.8%) sequence-specific DNA binding (46.2%) "IPR000485 (13%) IPR011991 (13%) IPR019887 (13%)" "AsnC-type HTH domain (13%) ArsR-like helix-turn-helix domain (13%) Transcription regulator AsnC/Lrp, ligand binding domain (13%)" SNTFSGSELDELGDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) WYLFPFPQTEVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR012944 (34.4%) IPR033985 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) RagB/SusD domain (34.4%) SusD-like, N-terminal (31.3%)" NDFLNNMTHELK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.13.3 (100%) histidine kinase (100%) "GO:0007234 (6.1%) GO:0016036 (5.7%) GO:0006418 (0.1%)" "GO:0005886 (16%) GO:0016020 (11.8%)" "GO:0000155 (28.1%) GO:0005524 (14%) GO:0000156 (6.1%)" "osmosensory signaling via phosphorelay pathway (6.1%) cellular response to phosphate starvation (5.7%) tRNA aminoacylation for protein translation (0.1%)" "plasma membrane (16%) membrane (11.8%)" "phosphorelay sensor kinase activity (28.1%) ATP binding (14%) phosphorelay response regulator activity (6.1%)" "IPR003661 (15.2%) IPR036097 (15.2%) IPR003594 (15.1%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (15.2%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (15.2%) Histidine kinase/HSP90-like ATPase domain (15.1%)" SPAELFPTYMLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) ADELLGFK root "2.3.1.39 (90.7%) 5.6.2.2 (4.7%) 6.2.1.13 (2.3%)" "[acyl-carrier-protein] S-malonyltransferase (90.7%) DNA topoisomerase (ATP-hydrolyzing) (4.7%) acetate--CoA ligase (ADP-forming) (2.3%)" "GO:0006633 (24.8%) GO:0006265 (1.4%) GO:0009306 (1.4%)" "GO:0005829 (25.5%) GO:0005886 (1.8%) GO:0009330 (1.4%)" "GO:0004314 (24.8%) GO:0005524 (2.1%) GO:0003677 (1.8%)" "fatty acid biosynthetic process (24.8%) DNA topological change (1.4%) protein secretion (1.4%)" "cytosol (25.5%) plasma membrane (1.8%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (1.4%)" "[acyl-carrier-protein] S-malonyltransferase activity (24.8%) ATP binding (2.1%) DNA binding (1.8%)" "IPR014043 (11.6%) IPR050858 (11.6%) IPR001227 (11.4%)" "Acyl transferase domain (11.6%) Malonyl CoA-ACP Transacylase/Polyketide Synthase FabD (11.6%) Acyl transferase domain superfamily (11.4%)" GDGDEAMSEEADTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005975 (46.8%) GO:0045493 (4.3%)" "GO:0016787 (44.7%) GO:0046559 (4.3%)" "carbohydrate metabolic process (46.8%) xylan catabolic process (4.3%)" "hydrolase activity (44.7%) alpha-glucuronidase activity (4.3%)" "IPR029018 (24.5%) IPR031924 (24.5%) IPR041437 (24.5%)" "Beta-hexosaminidase-like, domain 2 (24.5%) Glycosyl hydrolase family 115 (24.5%) Gylcosyl hydrolase 115 C-terminal domain (24.5%)" QNTWMVPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) ELGPDGLR root "1.1.1.47 (41.8%) 1.1.1.- (16.3%) 1.1.1.100 (9.2%)" "glucose 1-dehydrogenase [NAD(P)(+)] (41.8%) With NAD(+) or NADP(+) as acceptor (16.3%) 3-oxoacyl-[acyl-carrier-protein] reductase (9.2%)" "GO:0030497 (17.1%) GO:0006633 (4.1%) GO:0006629 (0.8%)" "GO:0016020 (0.8%) GO:0005581 (0.5%) GO:0005604 (0.5%)" "GO:0016616 (22.6%) GO:0016491 (17.1%) GO:0016787 (4.6%)" "fatty acid elongation (17.1%) fatty acid biosynthetic process (4.1%) lipid metabolic process (0.8%)" "membrane (0.8%) collagen trimer (0.5%) basement membrane (0.5%)" "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (22.6%) oxidoreductase activity (17.1%) hydrolase activity (4.6%)" "IPR002347 (25.6%) IPR036291 (25.4%) IPR020904 (14.7%)" "Short-chain dehydrogenase/reductase SDR (25.6%) NAD(P)-binding domain superfamily (25.4%) Short-chain dehydrogenase/reductase, conserved site (14.7%)" FDALNDMALLEASVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR004514 (10.9%) IPR020058 (10.9%) IPR020059 (10.9%)" "Glutamine-tRNA synthetase (10.9%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.9%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain (10.9%)" LVDVSVTNLFTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005615 (80%) GO:0005737 (10%) GO:0005886 (10%)" "extracellular space (80%) cytoplasm (10%) plasma membrane (10%)" "IPR001611 (16.4%) IPR027899 (16.4%) IPR041403 (16.4%)" "Leucine-rich repeat (16.4%) Domain of unknown function DUF4458 (16.4%) DUF4458 domain-containing protein, leucine-rich repeat (16.4%)" KPTVLNLLK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (5.9%) GO:0022625 (5.9%) "GO:0016740 (76.5%) GO:0003735 (5.9%) GO:0019843 (5.9%)" translation (5.9%) cytosolic large ribosomal subunit (5.9%) "transferase activity (76.5%) structural constituent of ribosome (5.9%) rRNA binding (5.9%)" "IPR001451 (44.8%) IPR011004 (41.4%) IPR005749 (3.4%)" "Hexapeptide repeat (44.8%) Trimeric LpxA-like superfamily (41.4%) Large ribosomal subunit protein uL15, bacteria (3.4%)" LLDLLNMVEGLTLHEPER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (50%) GO:0016491 (50%) cytosol (50%) oxidoreductase activity (50%) IPR004017 (100%) Cysteine-rich domain (100%) AALDAYYNETDVLLPENKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) TLDERPSAPLYFAYDDNDSVEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (31.9%) GO:0006730 (1.4%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (31.9%) one-carbon metabolic process (1.4%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.3%) IPR020628 (32.8%) IPR027417 (32.8%)" "Formate-tetrahydrofolate ligase, FTHFS (34.3%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (32.8%) P-loop containing nucleoside triphosphate hydrolase (32.8%)" LLGNQDTVYTGLANNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.11 (100%) pectinesterase (100%) "GO:0042545 (23.2%) GO:0045490 (22.1%)" GO:0009279 (23.2%) "GO:0030599 (23.2%) GO:0004557 (8.4%)" "cell wall modification (23.2%) pectin catabolic process (22.1%)" cell outer membrane (23.2%) "pectinesterase activity (23.2%) alpha-galactosidase activity (8.4%)" "IPR000070 (25.6%) IPR033131 (25.6%) IPR011050 (24.4%)" "Pectinesterase, catalytic (25.6%) Pectinesterase, Asp active site (25.6%) Pectin lyase fold/virulence factor (24.4%)" LSFATQLHYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.3.1.47 (85.7%) 2.3.1.50 (14.3%)" "8-amino-7-oxononanoate synthase (85.7%) serine C-palmitoyltransferase (14.3%)" "GO:0030170 (48.8%) GO:0008483 (23.2%) GO:0016740 (20%)" "pyridoxal phosphate binding (48.8%) transaminase activity (23.2%) transferase activity (20%)" "IPR001917 (16.8%) IPR004839 (16.8%) IPR050087 (16.8%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.8%) Aminotransferase, class I/classII, large domain (16.8%) 8-amino-7-oxononanoate synthase class-II (16.8%)" YNHNYGSPYYGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) ANVVASMQLLGDVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (10.8%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (10.8%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (17.3%) IPR005946 (17.3%) IPR029057 (17.3%)" "Phosphoribosyltransferase domain (17.3%) Ribose-phosphate pyrophosphokinase (17.3%) Phosphoribosyltransferase-like (17.3%)" EQVLAQQGQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" TLEYDPNR root "GO:0032543 (14%) GO:0002181 (3.1%) GO:0006412 (0.2%)" "GO:0005762 (14%) GO:0009507 (12.5%) GO:0015934 (3.2%)" "GO:0003735 (17.3%) GO:0016740 (16.7%) GO:0019843 (13.8%)" "mitochondrial translation (14%) cytoplasmic translation (3.1%) translation (0.2%)" "mitochondrial large ribosomal subunit (14%) chloroplast (12.5%) large ribosomal subunit (3.2%)" "structural constituent of ribosome (17.3%) transferase activity (16.7%) rRNA binding (13.8%)" "IPR022666 (11.4%) IPR002171 (11.4%) IPR012340 (11.4%)" "Large ribosomal subunit protein uL2, RNA-binding domain (11.4%) Large ribosomal subunit protein uL2 (11.4%) Nucleic acid-binding, OB-fold (11.4%)" SGDLNLSELAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (18.5%) "GO:0000155 (20.4%) GO:0003700 (20.4%) GO:0005524 (20.4%)" membrane (18.5%) "phosphorelay sensor kinase activity (20.4%) DNA-binding transcription factor activity (20.4%) ATP binding (20.4%)" "IPR001789 (6.8%) IPR003594 (6.8%) IPR003661 (6.8%)" "Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%)" TTFQLFGTLNPWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) YSYSGYTLGMLANSTQPNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (9.7%) GO:0009279 (90.3%) iron ion transport (9.7%) cell outer membrane (90.3%) "IPR039426 (14.7%) IPR012910 (14.2%) IPR023996 (14.2%)" "TonB-dependent receptor-like (14.7%) TonB-dependent receptor, plug domain (14.2%) TonB-dependent outer membrane protein, SusC/RagA (14.2%)" FGTNADYK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.2.1.- (50%) 3.2.1.1 (25%) 3.2.1.135 (25%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (50%) alpha-amylase (25%) neopullulanase (25%)" GO:0005975 (50%) "GO:0016798 (47.2%) GO:0004556 (1.4%) GO:0031216 (1.4%)" carbohydrate metabolic process (50%) "hydrolase activity, acting on glycosyl bonds (47.2%) alpha-amylase activity (1.4%) neopullulanase activity (1.4%)" "IPR006047 (15.1%) IPR015171 (14.6%) IPR019492 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (15.1%) Cyclomaltodextrinase, N-terminal (14.6%) Cyclo-malto-dextrinase, C-terminal (14.6%)" PAADGSSFGVSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.4%) GO:0008360 (14.1%) GO:0009252 (14.1%)" GO:0005737 (14.1%) "GO:0005524 (14.4%) GO:0008716 (14.4%) GO:0046872 (14.4%)" "cell wall organization (14.4%) regulation of cell shape (14.1%) peptidoglycan biosynthetic process (14.1%)" cytoplasm (14.1%) "ATP binding (14.4%) D-alanine-D-alanine ligase activity (14.4%) metal ion binding (14.4%)" "IPR000291 (14.4%) IPR005905 (14.4%) IPR011095 (14.4%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.4%) D-alanine--D-alanine ligase (14.4%) D-alanine--D-alanine ligase, C-terminal (14.4%)" NVTNLSPTLDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR041700 (100%) Outer membrane protein beta-barrel domain 3 (100%) STFDVVLAEVGGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20%) IPR008932 (20%) IPR013823 (20%)" "Large ribosomal subunit protein bL12 (20%) Large ribosomal subunit protein bL12, oligomerization (20%) Large ribosomal subunit protein bL12, C-terminal (20%)" KPVEVTAPSER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.8%) IPR022147 (14.8%) IPR052725 (14.8%)" "Glutamine synthetase, N-terminal domain (14.8%) Glutamine synthetase type III N-terminal (14.8%) Glutamine Synthetase Type-3 (14.8%)" LCAGETMSMDLTEPDAGSDLQR Pseudomonadati Bacteria Pseudomonadati "1.3.8.1 (66.7%) 1.3.99.- (33.3%)" "short-chain acyl-CoA dehydrogenase (66.7%) With other acceptors (33.3%)" "GO:0050660 (50%) GO:0016627 (47.7%) GO:0003995 (1.5%)" "flavin adenine dinucleotide binding (50%) oxidoreductase activity, acting on the CH-CH group of donors (47.7%) acyl-CoA dehydrogenase activity (1.5%)" "IPR006091 (10.1%) IPR009075 (10.1%) IPR013786 (10.1%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (10.1%) Acyl-CoA dehydrogenase/oxidase, C-terminal (10.1%) Acyl-CoA dehydrogenase/oxidase, N-terminal (10.1%)" GVLSGTLNQTLGETYSNVLTLPSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" ELEYEVVRDR root "6.3.5.5 (80.1%) 6.3.4.16 (19.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (80.1%) carbamoyl-phosphate synthase (ammonia) (19.9%)" "GO:0006541 (13.1%) GO:0006526 (11.7%) GO:0006221 (11.3%)" "GO:0005737 (12.8%) GO:0005951 (0.4%) GO:0005739 (0.3%)" "GO:0004088 (13.7%) GO:0005524 (13.7%) GO:0046872 (13.7%)" "glutamine metabolic process (13.1%) L-arginine biosynthetic process (11.7%) pyrimidine nucleotide biosynthetic process (11.3%)" "cytoplasm (12.8%) carbamoyl-phosphate synthase complex (0.4%) mitochondrion (0.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.7%) ATP binding (13.7%) metal ion binding (13.7%)" "IPR005479 (10.1%) IPR011761 (10.1%) IPR005483 (10%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%) Carbamoyl phosphate synthase, CPSase domain (10%)" ELLFFLLH root "2.7.7.7 (98.6%) 3.4.21.89 (1.4%)" "DNA-directed DNA polymerase (98.6%) signal peptidase I (1.4%)" "GO:0006261 (23.8%) GO:0007165 (0.5%) GO:0006465 (0.2%)" "GO:0009360 (23.8%) GO:0016020 (0.7%) GO:0005815 (0.2%)" "GO:0003677 (23.8%) GO:0003887 (23.8%) GO:0004252 (0.2%)" "DNA-templated DNA replication (23.8%) signal transduction (0.5%) signal peptide processing (0.2%)" "DNA polymerase III complex (23.8%) membrane (0.7%) microtubule organizing center (0.2%)" "DNA binding (23.8%) DNA-directed DNA polymerase activity (23.8%) serine-type endopeptidase activity (0.2%)" "IPR027417 (28.1%) IPR005790 (27.9%) IPR010372 (27.9%)" "P-loop containing nucleoside triphosphate hydrolase (28.1%) DNA polymerase III, delta subunit (27.9%) DNA polymerase III delta, N-terminal (27.9%)" GNTVLLLEHNLDVLK root 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) "GO:0006289 (11.5%) GO:0009432 (4.7%) GO:0006281 (0.5%)" "GO:0005737 (12%) GO:0009380 (11.5%) GO:0005829 (0%)" "GO:0003677 (12%) GO:0005524 (12%) GO:0016887 (11.9%)" "nucleotide-excision repair (11.5%) SOS response (4.7%) DNA repair (0.5%)" "cytoplasm (12%) excinuclease repair complex (11.5%) cytosol (0%)" "DNA binding (12%) ATP binding (12%) ATP hydrolysis activity (11.9%)" "IPR027417 (14.5%) IPR003439 (14.5%) IPR017871 (14.5%)" "P-loop containing nucleoside triphosphate hydrolase (14.5%) ABC transporter-like, ATP-binding domain (14.5%) ABC transporter-like, conserved site (14.5%)" HGGNFSFNAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.7%) IPR008969 (16.7%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (16.7%) Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%)" LNGSQEGLADLLEVQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" LLDHNFLDEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR025324 (100%) Protein of unknown function DUF4230 (100%) LLLSPGPGLPSEAGLLMDVLR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0000162 (32.7%) GO:0005829 (32.7%) "GO:0004049 (32.7%) GO:0016740 (1.8%)" L-tryptophan biosynthetic process (32.7%) cytosol (32.7%) "anthranilate synthase activity (32.7%) transferase activity (1.8%)" "IPR006221 (25%) IPR017926 (25%) IPR029062 (25%)" "Anthranilate synthase/para-aminobenzoate synthase like domain (25%) Glutamine amidotransferase (25%) Class I glutamine amidotransferase-like (25%)" TDHVDSGDLCAVLGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0000027 (10%) GO:0009409 (10%) GO:0010467 (10%)" "GO:0005829 (10%) GO:1990904 (10%)" "GO:0000049 (10%) GO:0003924 (10%) GO:0005525 (10%)" "ribosomal large subunit assembly (10%) response to cold (10%) gene expression (10%)" "cytosol (10%) ribonucleoprotein complex (10%)" "tRNA binding (10%) GTPase activity (10%) GTP binding (10%)" "IPR000640 (6.7%) IPR000795 (6.7%) IPR004161 (6.7%)" "Elongation factor EFG, domain V-like (6.7%) Translational (tr)-type GTP-binding domain (6.7%) Translation elongation factor EFTu-like, domain 2 (6.7%)" AWNVDKDGNPTTTESSTALDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (60%) IPR008160 (40%)" "Domain of unknown function DUF4988 (60%) Collagen triple helix repeat (40%)" LSGQWVEHLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri PFLTDWVLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.3%) IPR003385 (20.3%) IPR013783 (19.8%)" "Carbohydrate binding module family 20 (20.3%) Glycoside hydrolase, family 77 (20.3%) Immunoglobulin-like fold (19.8%)" NGAASQVNPPGALLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023997 (15%) IPR039426 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%) TonB-dependent receptor-like (15%)" NACWVPGTDHASLATEAK root "6.1.1.9 (99.9%) 4.2.1.47 (0.1%)" "valine--tRNA ligase (99.9%) GDP-mannose 4,6-dehydratase (0.1%)" "GO:0006438 (20%) GO:0005975 (0%) GO:0006508 (0%)" "GO:0005829 (20%) GO:0016020 (0%)" "GO:0004832 (20%) GO:0005524 (20%) GO:0002161 (19.8%)" "valyl-tRNA aminoacylation (20%) carbohydrate metabolic process (0%) proteolysis (0%)" "cytosol (20%) membrane (0%)" "valine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.8%)" "IPR002300 (9.2%) IPR002303 (9.2%) IPR014729 (9.2%)" "Aminoacyl-tRNA synthetase, class Ia (9.2%) Valine-tRNA ligase (9.2%) Rossmann-like alpha/beta/alpha sandwich fold (9.2%)" QDDPAGGQLYPSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) VSNQGNLLEFALGYTHPLFLQLPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" AGLHVLLTDNEKPYHER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (31.6%) GO:0005829 (31.6%) "GO:0008926 (31.6%) GO:0009026 (5.3%)" mannitol catabolic process (31.6%) cytosol (31.6%) "mannitol-1-phosphate 5-dehydrogenase activity (31.6%) tagaturonate reductase activity (5.3%)" "IPR013118 (21.6%) IPR013131 (21.6%) IPR008927 (18.9%)" "Mannitol dehydrogenase, C-terminal (21.6%) Mannitol dehydrogenase, N-terminal (21.6%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.9%)" LLAYSGLMEDKEVTWMPAYGPEQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.2.7.1 (60%) 1.2.7.3 (20%) 1.2.7.7 (20%)" "pyruvate synthase (60%) 2-oxoglutarate synthase (20%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (20%)" "GO:0016903 (93.2%) GO:0019164 (4.1%) GO:0016625 (1.4%)" "oxidoreductase activity, acting on the aldehyde or oxo group of donors (93.2%) pyruvate synthase activity (4.1%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (1.4%)" "IPR002869 (33.2%) IPR019752 (33.2%) IPR052554 (33.2%)" "Pyruvate-flavodoxin oxidoreductase, central domain (33.2%) Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (33.2%) 2-oxoglutarate synthase subunit KorC (33.2%)" NLFNDAK root "2.6.1.1 (71.1%) 5.2.1.8 (17.4%) 2.1.1.13 (4.7%)" "aspartate transaminase (71.1%) peptidylprolyl isomerase (17.4%) methionine synthase (4.7%)" "GO:0006520 (10.6%) GO:0006289 (2.8%) GO:0015031 (2.6%)" "GO:0005634 (3.9%) GO:0016020 (3.9%) GO:0005737 (3%)" "GO:0030170 (10.7%) GO:0004069 (7.7%) GO:0046872 (5.1%)" "amino acid metabolic process (10.6%) nucleotide-excision repair (2.8%) protein transport (2.6%)" "nucleus (3.9%) membrane (3.9%) cytoplasm (3%)" "pyridoxal phosphate binding (10.7%) L-aspartate:2-oxoglutarate aminotransferase activity (7.7%) metal ion binding (5.1%)" "IPR000796 (7.4%) IPR004839 (7.4%) IPR015421 (7.2%)" "Aspartate/other aminotransferase (7.4%) Aminotransferase, class I/classII, large domain (7.4%) Pyridoxal phosphate-dependent transferase, major domain (7.2%)" TDVVVQPR Bacteria Bacteria "6.6.1.2 (94.7%) 3.1.3.3 (5.3%)" "cobaltochelatase (94.7%) phosphoserine phosphatase (5.3%)" GO:0006564 (0.5%) "GO:0016020 (88.7%) GO:0005737 (0.5%)" "GO:0051116 (8.2%) GO:0016874 (1%) GO:0000287 (0.5%)" L-serine biosynthetic process (0.5%) "membrane (88.7%) cytoplasm (0.5%)" "cobaltochelatase activity (8.2%) ligase activity (1%) magnesium ion binding (0.5%)" "IPR003672 (97.8%) IPR004469 (0.5%) IPR023214 (0.5%)" "CobN/magnesium chelatase (97.8%) Phosphoserine phosphatase (0.5%) HAD superfamily (0.5%)" TELTDLYNQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" NEFTDFK root 3.6.1.7 (100%) acylphosphatase (100%) "GO:0003677 (24.3%) GO:0003700 (24.3%) GO:0008270 (13.5%)" "DNA binding (24.3%) DNA-binding transcription factor activity (24.3%) zinc ion binding (13.5%)" "IPR000524 (10.6%) IPR008920 (10.6%) IPR011711 (10.6%)" "Transcription regulator HTH, GntR (10.6%) Transcription regulator FadR/GntR, C-terminal (10.6%) GntR, C-terminal (10.6%)" LLGMLYLK root "1.10.3.- (25%) 2.3.1.48 (25%) 2.4.-.- (25%)" "With oxygen as acceptor (25%) histone acetyltransferase (25%) Glycosyltransferases (25%)" "GO:0019646 (9.6%) GO:0006891 (1.4%) GO:0006896 (1.4%)" "GO:0005886 (12.1%) GO:0070069 (9.6%) GO:0016020 (2.7%)" "GO:0009055 (9.6%) GO:0016682 (9.6%) GO:0046872 (9.6%)" "aerobic electron transport chain (9.6%) intra-Golgi vesicle-mediated transport (1.4%) Golgi to vacuole transport (1.4%)" "plasma membrane (12.1%) cytochrome complex (9.6%) membrane (2.7%)" "electron transfer activity (9.6%) oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (9.6%) metal ion binding (9.6%)" "IPR003317 (27.1%) IPR011990 (4.5%) IPR003439 (3.9%)" "Cytochrome ubiquinol oxidase subunit 2 (27.1%) Tetratricopeptide-like helical domain superfamily (4.5%) ABC transporter-like, ATP-binding domain (3.9%)" YLPLNLFPSDLMDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.6%) IPR012910 (20.6%) IPR008969 (19.6%)" "TonB-dependent receptor-like, beta-barrel (20.6%) TonB-dependent receptor, plug domain (20.6%) Carboxypeptidase-like, regulatory domain superfamily (19.6%)" YNNNDEQGGYQPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.5%) IPR002942 (11.5%) IPR006145 (11.5%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.5%) RNA-binding S4 domain (11.5%) Pseudouridine synthase, RsuA/RluA-like (11.5%)" GLSPYPGAWTELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.9 (100%) methionyl-tRNA formyltransferase (100%) GO:0005829 (50%) GO:0004479 (50%) cytosol (50%) methionyl-tRNA formyltransferase activity (50%) "IPR002376 (13.1%) IPR005793 (13.1%) IPR005794 (13.1%)" "Formyl transferase, N-terminal (13.1%) Formyl transferase, C-terminal (13.1%) Methionyl-tRNA formyltransferase (13.1%)" WEQSYQNCYFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009313 (49.2%) GO:0005975 (1.7%)" GO:0004556 (49.2%) "oligosaccharide catabolic process (49.2%) carbohydrate metabolic process (1.7%)" alpha-amylase activity (49.2%) "IPR006047 (27%) IPR017853 (25.2%) IPR045857 (25.2%)" "Glycosyl hydrolase family 13, catalytic domain (27%) Glycoside hydrolase superfamily (25.2%) Oligo-1,6-glucosidase, domain 2 (25.2%)" NLYDFQQLTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR039968 (51.9%) IPR016181 (48.1%)" "Bacterial ceramide synthase-like (51.9%) Acyl-CoA N-acyltransferase (48.1%)" YADNFHLEGDANEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.5%) IPR033985 (31.3%) IPR012944 (28.9%)" "Tetratricopeptide-like helical domain superfamily (32.5%) SusD-like, N-terminal (31.3%) RagB/SusD domain (28.9%)" KYVATLYQDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.7%) IPR029483 (14.7%) IPR029486 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%)" GAFDDAEAQKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) "GO:0005737 (25%) GO:0015935 (25%)" GO:0003735 (25%) translation (25%) "cytoplasm (25%) small ribosomal subunit (25%)" structural constituent of ribosome (25%) "IPR000307 (50%) IPR023803 (50%)" "Small ribosomal subunit protein bS16 (50%) Small ribosomal subunit protein bS16 domain superfamily (50%)" LYLALGSR root "1.4.1.13 (66.7%) 2.7.1.6 (11.1%) 2.7.13.3 (11.1%)" "glutamate synthase (NADPH) (66.7%) galactokinase (11.1%) histidine kinase (11.1%)" "GO:0006508 (2.6%) GO:0046425 (2.2%) GO:0006355 (0.4%)" "GO:0016020 (22.3%) GO:0005634 (3.7%) GO:0005615 (2.4%)" "GO:0005385 (21.7%) GO:0051536 (10.7%) GO:0016491 (10.1%)" "proteolysis (2.6%) regulation of receptor signaling pathway via JAK-STAT (2.2%) regulation of DNA-templated transcription (0.4%)" "membrane (22.3%) nucleus (3.7%) extracellular space (2.4%)" "zinc ion transmembrane transporter activity (21.7%) iron-sulfur cluster binding (10.7%) oxidoreductase activity (10.1%)" "IPR003689 (17.9%) IPR023753 (9%) IPR028261 (9%)" "Zinc/iron permease (17.9%) FAD/NAD(P)-binding domain (9%) Dihydroprymidine dehydrogenase domain II (9%)" LLDSNKYDLCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" GNPTVEVEVSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (17%) "GO:0000015 (17%) GO:0005576 (16.1%) GO:0009986 (16.1%)" "GO:0000287 (17%) GO:0004634 (17%)" glycolytic process (17%) "phosphopyruvate hydratase complex (17%) extracellular region (16.1%) cell surface (16.1%)" "magnesium ion binding (17%) phosphopyruvate hydratase activity (17%)" "IPR000941 (17.1%) IPR020811 (17.1%) IPR029017 (17.1%)" "Enolase (17.1%) Enolase, N-terminal (17.1%) Enolase-like, N-terminal (17.1%)" SEDLFNPFSLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (41.3%) IPR012547 (37.5%) IPR027417 (21.3%)" "AAA-ATPase-like domain (41.3%) PD-(D/E)XK nuclease superfamily 9 (37.5%) P-loop containing nucleoside triphosphate hydrolase (21.3%)" TGLTSQYPQYSPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.3%) IPR011659 (14.3%) IPR012393 (14.3%)" "Tail specific protease (14.3%) WD40-like beta-propeller (14.3%) Tricorn protease (14.3%)" TTDLVANLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) VEENNFGLR root 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.5%) GO:0017038 (11.5%) GO:0043952 (11.5%)" "GO:0005886 (11.5%) GO:0005829 (11.5%) GO:0031522 (11.5%)" "GO:0005524 (11.5%) GO:0046872 (7.8%) GO:0004386 (0.2%)" "protein targeting (11.5%) protein import (11.5%) protein transport by the Sec complex (11.5%)" "plasma membrane (11.5%) cytosol (11.5%) cell envelope Sec protein transport complex (11.5%)" "ATP binding (11.5%) metal ion binding (7.8%) helicase activity (0.2%)" "IPR000185 (8%) IPR011116 (8%) IPR014018 (7.9%)" "Protein translocase subunit SecA (8%) SecA Wing/Scaffold (8%) SecA motor DEAD (7.9%)" YLKGEDTSTNPMATLFAWSGALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20%) GO:0006102 (20%)" "GO:0000287 (20%) GO:0004450 (20%) GO:0051287 (20%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "magnesium ion binding (20%) isocitrate dehydrogenase (NADP+) activity (20%) NAD binding (20%)" "IPR004790 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" DADAPEVLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.4%) GO:0008360 (12.4%) GO:0009252 (12.4%)" GO:0005886 (12.4%) "GO:0050511 (12.4%) GO:0051991 (0.8%)" "carbohydrate metabolic process (12.4%) regulation of cell shape (12.4%) peptidoglycan biosynthetic process (12.4%)" plasma membrane (12.4%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.4%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (0.8%)" "IPR004276 (33.3%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.3%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" ADDLAFVGWDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (12.5%) IPR002772 (12.5%) IPR013783 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (12.5%) Glycoside hydrolase family 3 C-terminal domain (12.5%) Immunoglobulin-like fold (12.5%)" YQDAEDECYGFLNEYPDSKDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (34.4%) IPR039565 (34.4%) IPR011990 (31.3%)" "Outer membrane protein assembly factor BamD (34.4%) Outer membrane lipoprotein BamD-like (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" MDLVEQLKELVDMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016787 (100%) hydrolase activity (100%) "IPR003495 (23.4%) IPR011629 (23.4%) IPR051927 (23.4%)" "CobW/HypB/UreG, nucleotide-binding domain (23.4%) Zinc chaperone CobW-like, C-terminal (23.4%) Zinc Chaperone and cDPG Synthetase (23.4%)" SSNNSEGSTLYVTASPCLECAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006220 (22.6%) GO:0005737 (25.8%) "GO:0004132 (25.8%) GO:0008270 (25.8%)" pyrimidine nucleotide metabolic process (22.6%) cytoplasm (25.8%) "dCMP deaminase activity (25.8%) zinc ion binding (25.8%)" "IPR002125 (17.4%) IPR015517 (17.4%) IPR016192 (17.4%)" "Cytidine and deoxycytidylate deaminase domain (17.4%) Deoxycytidylate deaminase-related (17.4%) APOBEC/CMP deaminase, zinc-binding (17.4%)" ELSLLFQSQTR Pseudomonadati Bacteria Pseudomonadati GO:0030490 (33.3%) GO:0005829 (33.3%) GO:0043024 (33.3%) maturation of SSU-rRNA (33.3%) cytosol (33.3%) ribosomal small subunit binding (33.3%) "IPR000238 (33.3%) IPR015946 (33.3%) IPR023799 (33.3%)" "Ribosome-binding factor A (33.3%) K homology domain-like, alpha/beta (33.3%) Ribosome-binding factor A domain superfamily (33.3%)" FQMNLPNKEGSNER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (28.6%) IPR017853 (25%) IPR045857 (25%)" "Glycosyl hydrolase family 13, catalytic domain (28.6%) Glycoside hydrolase superfamily (25%) Oligo-1,6-glucosidase, domain 2 (25%)" EQPDAAVSVDTYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (20%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (20%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (20%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (20%)" "IPR000489 (25.2%) IPR006390 (25.2%) IPR045031 (25.2%)" "Pterin-binding domain (25.2%) Dihydropteroate synthase domain (25.2%) Dihydropteroate synthase-like (25.2%)" LYELLWK root "5.6.2.1 (98.4%) 5.99.1.2 (0.8%) 3.1.-.- (0.3%)" "DNA topoisomerase (98.4%) Transferred entry: 5.6.2.1 (0.8%) Acting on ester bonds (0.3%)" "GO:0006265 (22.3%) GO:0006355 (0.3%) GO:0000724 (0.1%)" "GO:0005694 (6.7%) GO:0005886 (0.4%) GO:0005829 (0.3%)" "GO:0003677 (22.3%) GO:0003917 (22.3%) GO:0046872 (15.3%)" "DNA topological change (22.3%) regulation of DNA-templated transcription (0.3%) double-strand break repair via homologous recombination (0.1%)" "chromosome (6.7%) plasma membrane (0.4%) cytosol (0.3%)" "DNA binding (22.3%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (22.3%) metal ion binding (15.3%)" "IPR000380 (7%) IPR003602 (7%) IPR013497 (7%)" "DNA topoisomerase, type IA (7%) DNA topoisomerase, type IA, DNA-binding domain (7%) DNA topoisomerase, type IA, central (7%)" GALSFAMNVAELLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.3%) IPR032790 (20.3%) IPR024742 (20%)" "Glycogen debranching enzyme (20.3%) Glycogen debranching enzyme, C-terminal (20.3%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20%)" NFTFFALGTGNFGAYGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" SDENNFTLQLTDLPFADHPSAVYAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25.8%) "GO:0000155 (24.7%) GO:0003700 (24.7%) GO:0043565 (24.7%)" membrane (25.8%) "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (24.7%) sequence-specific DNA binding (24.7%)" "IPR011123 (15.4%) IPR011110 (14.8%) IPR018060 (14.8%)" "Two component regulator three Y (15.4%) Two component regulator propeller (14.8%) AraC-like, DNA binding HTH domain (14.8%)" LHQDLATLLYSLDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.6%) IPR006584 (12.6%) IPR006710 (12.6%)" "Carbohydrate binding module family 6 (12.6%) Cellulose binding, type IV (12.6%) Glycoside hydrolase, family 43 (12.6%)" DLPLLCNQWCNVMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR004499 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Proline-tRNA ligase, class IIa, archaeal-type (11.3%)" KNALVTSFNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.7%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.7%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" LALMLNSPYNANAMDLYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FYAATQELCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) GO:0006281 (27.5%) GO:0005829 (27.5%) "GO:0008967 (27.5%) GO:2001070 (17.6%)" DNA repair (27.5%) cytosol (27.5%) "phosphoglycolate phosphatase activity (27.5%) starch binding (17.6%)" "IPR006439 (11.6%) IPR041492 (11.6%) IPR050155 (11.6%)" "HAD hydrolase, subfamily IA (11.6%) Haloacid dehalogenase-like hydrolase (11.6%) HAD-like hydrolase superfamily (11.6%)" ALKDAPVVTR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" VTLNYAGTVTFSTLHDVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" GEPFECGLPTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0005886 (20.2%) GO:0030964 (20.2%)" "GO:0008137 (20.2%) GO:0048038 (20.2%) GO:0050136 (19.2%)" "plasma membrane (20.2%) NADH dehydrogenase complex (20.2%)" "NADH dehydrogenase (ubiquinone) activity (20.2%) quinone binding (20.2%) NADH dehydrogenase (quinone) (non-electrogenic) activity (19.2%)" "IPR000440 (33.9%) IPR038430 (33.9%) IPR023043 (32.2%)" "NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 (33.9%) NADH:ubiquinone oxidoreductase, subunit 3 superfamily (33.9%) NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid (32.2%)" QQALFLTDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae EAWTTVMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.1.77 (50%) 4.1.3.- (50%)" "N-carbamoyl-D-amino-acid hydrolase (50%) Oxo-acid-lyases (50%)" GO:0033388 (41.9%) "GO:0050126 (41.9%) GO:0016746 (13.3%) GO:0016829 (1.4%)" putrescine biosynthetic process from arginine (41.9%) "N-carbamoylputrescine amidase activity (41.9%) acyltransferase activity (13.3%) lyase activity (1.4%)" "IPR003010 (33.6%) IPR050345 (33.6%) IPR036526 (32.8%)" "Carbon-nitrogen hydrolase (33.6%) Aliphatic Amidase/Beta-Ureidopropionase (33.6%) Carbon-nitrogen hydrolase superfamily (32.8%)" FQMNLPNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (28.6%) IPR017853 (25%) IPR045857 (25%)" "Glycosyl hydrolase family 13, catalytic domain (28.6%) Glycoside hydrolase superfamily (25%) Oligo-1,6-glucosidase, domain 2 (25%)" GTALTYPLSTNLYWQFLTNKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0042918 (27.8%) GO:0042597 (72.2%) alkanesulfonate transmembrane transport (27.8%) periplasmic space (72.2%) IPR015168 (100%) SsuA/THI5-like (100%) VDFSSYLSFTQVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LLDLLNR root "3.1.3.48 (22.7%) 2.7.11.1 (8.1%) 3.6.4.13 (7.3%)" "protein-tyrosine-phosphatase (22.7%) non-specific serine/threonine protein kinase (8.1%) RNA helicase (7.3%)" "GO:0070374 (2.2%) GO:0015031 (1.2%) GO:0007030 (1.1%)" "GO:0005737 (6.2%) GO:0005829 (3.4%) GO:0016020 (3.1%)" "GO:0005524 (5.6%) GO:0004726 (2.2%) GO:0030971 (2.2%)" "positive regulation of ERK1 and ERK2 cascade (2.2%) protein transport (1.2%) Golgi organization (1.1%)" "cytoplasm (6.2%) cytosol (3.4%) membrane (3.1%)" "ATP binding (5.6%) non-membrane spanning protein tyrosine phosphatase activity (2.2%) receptor tyrosine kinase binding (2.2%)" "IPR027417 (3.5%) IPR000387 (1.6%) IPR003595 (1.6%)" "P-loop containing nucleoside triphosphate hydrolase (3.5%) Tyrosine-specific protein phosphatases domain (1.6%) Protein-tyrosine phosphatase, catalytic (1.6%)" FSELQFVWNEADR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.8%) "GO:0004553 (33.8%) GO:0030246 (32.5%)" carbohydrate metabolic process (33.8%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.8%) carbohydrate binding (32.5%)" "IPR000322 (12.7%) IPR025887 (12.7%) IPR033403 (12.7%)" "Glycoside hydrolase family 31, TIM barrel domain (12.7%) Glycoside hydrolase family 31, N-terminal domain (12.7%) Domain of unknown function DUF5110 (12.7%)" YNTLYEAFCNEYGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.2%) GO:0005975 (1.8%)" "GO:0008422 (48.2%) GO:0004553 (1.8%)" "glucan catabolic process (48.2%) carbohydrate metabolic process (1.8%)" "beta-glucosidase activity (48.2%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.8%)" "IPR002772 (13.1%) IPR001764 (12.6%) IPR026891 (12.6%)" "Glycoside hydrolase family 3 C-terminal domain (13.1%) Glycoside hydrolase, family 3, N-terminal (12.6%) Fibronectin type III-like domain (12.6%)" CVDACPMGLEPYLLATLSVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) GO:0022900 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0046872 (20%) GO:0051539 (20%)" electron transport chain (20%) plasma membrane (20%) "electron transfer activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR010208 (14.4%) IPR011538 (14.4%) IPR017896 (14.4%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.4%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" SDLLADFRENATELGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" WYDREDHTLFDVCADDHCQR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0030435 (66.5%) GO:0030288 (33%) GO:0016740 (0.5%) sporulation resulting in formation of a cellular spore (66.5%) outer membrane-bounded periplasmic space (33%) transferase activity (0.5%) "IPR013486 (18.3%) IPR013693 (18.3%) IPR046320 (10.3%)" "Sporulation stage II protein D, amidase enhancer LytB (18.3%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (18.3%) Domain of unknown function DUF4922 (10.3%)" FGLQLQMPATFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.6%) GO:0009341 (25.6%) "GO:0004565 (25.6%) GO:0030246 (23.2%)" lactose catabolic process (25.6%) beta-galactosidase complex (25.6%) "beta-galactosidase activity (25.6%) carbohydrate binding (23.2%)" "IPR004199 (8.4%) IPR050347 (8.4%) IPR006102 (8%)" "Beta galactosidase small chain/ domain 5 (8.4%) Bacterial Beta-galactosidase (8.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8%)" VSKDDYTGHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AYHNETGLAGYTLVYHSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (50.7%) IPR029052 (49.3%)" "Fructose-1,6-bisphosphatase class 3 (50.7%) Metallo-dependent phosphatase-like (49.3%)" ASEENEHADVMLTTPEGVDVLCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.65 (100%) phosphatidylserine decarboxylase (100%) GO:0006646 (33.3%) GO:0005886 (33.3%) GO:0004609 (33.3%) phosphatidylethanolamine biosynthetic process (33.3%) plasma membrane (33.3%) phosphatidylserine decarboxylase activity (33.3%) "IPR003817 (50%) IPR033175 (50%)" "Phosphatidylserine decarboxylase-related (50%) Phosphatidylserine decarboxylase, prokaryotes (50%)" TVFFPLDGDVDFYSYYPQTTVNDYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025049 (53.8%) IPR042278 (46.2%)" "Fimbrillin-like 1 (53.8%) Fimbrillin-like 1, N-terminal (46.2%)" STVVPFR root "6.3.4.20 (95.4%) 2.1.1.- (1%) 6.1.2.- (1%)" "7-cyano-7-deazaguanine synthase (95.4%) Methyltransferases (1%) Acid--alcohol ligases (ester synthases) (1%)" "GO:0008616 (20%) GO:0043041 (1.1%) GO:0044550 (1.1%)" "GO:0005737 (1.2%) GO:0005886 (0.7%) GO:0005634 (0.4%)" "GO:0005524 (20.5%) GO:0008270 (20.3%) GO:0016879 (19.7%)" "tRNA queuosine(34) biosynthetic process (20%) amino acid activation for nonribosomal peptide biosynthetic process (1.1%) secondary metabolite biosynthetic process (1.1%)" "cytoplasm (1.2%) plasma membrane (0.7%) nucleus (0.4%)" "ATP binding (20.5%) zinc ion binding (20.3%) ligase activity, forming carbon-nitrogen bonds (19.7%)" "IPR018317 (24.9%) IPR014729 (24.6%) IPR027417 (6.3%)" "Queuosine biosynthesis protein QueC (24.9%) Rossmann-like alpha/beta/alpha sandwich fold (24.6%) P-loop containing nucleoside triphosphate hydrolase (6.3%)" YPSCLLR root "2.7.11.1 (28.6%) 5.1.3.3 (28.6%) 2.1.2.2 (14.3%)" "non-specific serine/threonine protein kinase (28.6%) aldose 1-epimerase (28.6%) phosphoribosylglycinamide formyltransferase 1 (14.3%)" "GO:0016226 (94.4%) GO:0042742 (0.6%) GO:0006006 (0.2%)" "GO:0005886 (0.8%) GO:0016020 (0.2%) GO:1990229 (0.1%)" "GO:0005524 (0.9%) GO:0004674 (0.9%) GO:0030246 (0.3%)" "iron-sulfur cluster assembly (94.4%) defense response to bacterium (0.6%) glucose metabolic process (0.2%)" "plasma membrane (0.8%) membrane (0.2%) iron-sulfur cluster assembly complex (0.1%)" "ATP binding (0.9%) protein serine/threonine kinase activity (0.9%) carbohydrate binding (0.3%)" "IPR000825 (19.7%) IPR055346 (19.7%) IPR037284 (19.7%)" "SUF system FeS cluster assembly, SufBD core domain (19.7%) SUF system FeS cluster assembly, SufBD (19.7%) SUF system FeS cluster assembly, SufBD superfamily (19.7%)" NMMEEKDWNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) HDSSYQLWK Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" TEDNWLGELTGEQFNNLGMNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0006465 (32.5%) GO:0006508 (1.2%)" GO:0016020 (32.5%) GO:0008236 (33.7%) "signal peptide processing (32.5%) proteolysis (1.2%)" membrane (32.5%) serine-type peptidase activity (33.7%) "IPR002142 (17.2%) IPR047217 (17.2%) IPR004634 (16.6%)" "Peptidase S49 (17.2%) Signal peptide peptidase A, N-terminal (17.2%) Peptidase S49, protease IV (16.6%)" NLGSMATLGR Bacteria Bacteria "1.6.5.9 (95.8%) 1.6.5.- (4.2%)" "NADH:ubiquinone reductase (non-electrogenic) (95.8%) With a quinone or similar compound as acceptor (4.2%)" "GO:0016020 (11.1%) GO:0005739 (3.7%)" "GO:0003954 (83.3%) GO:0050136 (1.9%)" "membrane (11.1%) mitochondrion (3.7%)" "NADH dehydrogenase activity (83.3%) NADH dehydrogenase (quinone) (non-electrogenic) activity (1.9%)" "IPR023753 (25%) IPR045024 (25%) IPR054585 (25%)" "FAD/NAD(P)-binding domain (25%) Alternative NADH dehydrogenase (25%) External alternative NADH-ubiquinone oxidoreductase-like, C-terminal domain (25%)" METLLSLAGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.24 (100%) dephospho-CoA kinase (100%) GO:0015937 (20%) GO:0005737 (20%) "GO:0004140 (20%) GO:0005524 (20%) GO:0016301 (20%)" coenzyme A biosynthetic process (20%) cytoplasm (20%) "dephospho-CoA kinase activity (20%) ATP binding (20%) kinase activity (20%)" "IPR041218 (25%) IPR049280 (25%) IPR049281 (24.4%)" "Domain of unknown function DUF5606 (25%) Domain of unknown function DUF6852 (25%) BVU_3817-like, C-terminal domain superfamily (24.4%)" PVLNEESGYTEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (34.8%) IPR011990 (30.4%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (30.4%)" TSGYGFDPYSESAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006520 (50%) GO:0016829 (50%) amino acid metabolic process (50%) lyase activity (50%) "IPR001597 (25.7%) IPR015421 (24.8%) IPR015422 (24.8%)" "Aromatic amino acid beta-eliminating lyase/threonine aldolase (25.7%) Pyridoxal phosphate-dependent transferase, major domain (24.8%) Pyridoxal phosphate-dependent transferase, small domain (24.8%)" GQGPAFDNSLFEDFCEFGLGMVMGNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (13.9%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (13.9%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" AALEATTNALKEALLAGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030261 (25%) GO:0005829 (25%) "GO:0003677 (25%) GO:0030527 (25%)" chromosome condensation (25%) cytosol (25%) "DNA binding (25%) structural constituent of chromatin (25%)" "IPR000119 (33.3%) IPR010992 (33.3%) IPR020816 (33.3%)" "Histone-like DNA-binding protein (33.3%) Integration host factor (IHF)-like DNA-binding domain superfamily (33.3%) Histone-like DNA-binding protein, conserved site (33.3%)" LDLSSLNQSTRPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (25%) "GO:0003743 (25%) GO:0003924 (25%) GO:0005525 (25%)" cytoplasm (25%) "translation initiation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000178 (8.8%) IPR000795 (8.8%) IPR005225 (8.8%)" "Translation initiation factor IF-2, bacterial-like (8.8%) Translational (tr)-type GTP-binding domain (8.8%) Small GTP-binding domain (8.8%)" QMNKPYSADELAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) ELLLLSTPFDLPGFKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.24 (100%) glucose-1-phosphate thymidylyltransferase (100%) "GO:0008879 (50.3%) GO:0046872 (49.7%)" "glucose-1-phosphate thymidylyltransferase activity (50.3%) metal ion binding (49.7%)" "IPR005835 (33.9%) IPR005907 (33.9%) IPR029044 (32.2%)" "Nucleotidyl transferase domain (33.9%) Glucose-1-phosphate thymidylyltransferase, short form (33.9%) Nucleotide-diphospho-sugar transferases (32.2%)" GSSLMELLSNLTSDNLLLQLADPSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006271 (16.7%) "GO:0005737 (16.7%) GO:0009360 (16.7%)" "GO:0003677 (16.7%) GO:0003887 (16.7%) GO:0008408 (16.7%)" DNA strand elongation involved in DNA replication (16.7%) "cytoplasm (16.7%) DNA polymerase III complex (16.7%)" "DNA binding (16.7%) DNA-directed DNA polymerase activity (16.7%) 3'-5' exonuclease activity (16.7%)" "IPR001001 (20%) IPR022634 (20%) IPR022635 (20%)" "DNA polymerase III, beta sliding clamp (20%) DNA polymerase III, beta sliding clamp, N-terminal (20%) DNA polymerase III, beta sliding clamp, C-terminal (20%)" VNDTTAGFVCYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.-.- (100%) Glycosyltransferases (100%) GO:0009247 (33.3%) GO:0016020 (33.3%) GO:0004582 (33.3%) glycolipid biosynthetic process (33.3%) membrane (33.3%) dolichyl-phosphate beta-D-mannosyltransferase activity (33.3%) "IPR001173 (33.3%) IPR029044 (33.3%) IPR039528 (33.3%)" "Glycosyltransferase 2-like (33.3%) Nucleotide-diphospho-sugar transferases (33.3%) DPM1-like (33.3%)" DMVNWTDHGSPLDLSSFSWADDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" NLFLPYVGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006814 (33.3%) GO:0016020 (33.3%) GO:0015297 (33.3%) sodium ion transport (33.3%) membrane (33.3%) antiporter activity (33.3%) "IPR004680 (50%) IPR045016 (50%)" "Citrate transporter-like domain (50%) Na(+)/H(+) antiporter NhaD-like (50%)" LDLKDVDR root "3.2.2.6 (40%) 3.1.-.- (10%) 3.2.1.21 (10%)" "ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase (40%) Acting on ester bonds (10%) beta-glucosidase (10%)" "GO:0043328 (12.8%) GO:0005975 (6.2%) GO:0006270 (1.6%)" "GO:0000814 (12.8%) GO:0031902 (12.8%) GO:0005658 (1.6%)" "GO:0032266 (12.8%) GO:0043130 (12.8%) GO:0046872 (10.9%)" "protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (12.8%) carbohydrate metabolic process (6.2%) DNA replication initiation (1.6%)" "ESCRT II complex (12.8%) late endosome membrane (12.8%) alpha DNA polymerase:primase complex (1.6%)" "phosphatidylinositol-3-phosphate binding (12.8%) ubiquitin binding (12.8%) metal ion binding (10.9%)" "IPR021648 (7.3%) IPR037855 (7.3%) IPR011993 (7.3%)" "Vacuolar protein sorting protein 36, GLUE domain (7.3%) Vacuolar protein sorting protein 36 (7.3%) PH-like domain superfamily (7.3%)" HVSFAYTDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (23.1%) GO:0016020 (1.9%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (23.1%) membrane (1.9%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.6%) IPR003593 (14.6%) IPR011527 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) AAA+ ATPase domain (14.6%) ABC transporter type 1, transmembrane domain (14.6%)" GKWDASCSNELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (22.9%) GO:0006080 (20%) GO:0030245 (8.6%)" "GO:0005576 (8.6%) GO:0009986 (8.6%)" "GO:0016985 (20%) GO:0008422 (8.6%) GO:0004553 (2.9%)" "polysaccharide catabolic process (22.9%) substituted mannan metabolic process (20%) cellulose catabolic process (8.6%)" "extracellular region (8.6%) cell surface (8.6%)" "mannan endo-1,4-beta-mannosidase activity (20%) beta-glucosidase activity (8.6%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.9%)" "IPR001547 (28.9%) IPR017853 (23.7%) IPR022790 (21.1%)" "Glycoside hydrolase, family 5 (28.9%) Glycoside hydrolase superfamily (23.7%) Glycosyl hydrolase family 26 domain (21.1%)" VETNGGAFEQVNLLAGENPNDAVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.4.1.1 (100%) pyruvate carboxylase (100%) GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (21.3%) IPR003379 (21.3%) IPR055268 (21.3%)" "Pyruvate carboxyltransferase (21.3%) Carboxylase, conserved domain (21.3%) Pyruvate carboxylase-like (21.3%)" VYSFSFR root 1.14.13.- (100%) With NADH or NADPH as one donor, and incorporation of one atom of oxygen (100%) "GO:0030026 (4.8%) GO:0006826 (3.8%) GO:0006352 (1%)" "GO:0016020 (17.1%) GO:0005774 (3.8%) GO:0005886 (1.9%)" "GO:0005524 (19%) GO:0004499 (7.6%) GO:0050660 (7.6%)" "intracellular manganese ion homeostasis (4.8%) iron ion transport (3.8%) DNA-templated transcription initiation (1%)" "membrane (17.1%) vacuolar membrane (3.8%) plasma membrane (1.9%)" "ATP binding (19%) N,N-dimethylaniline monooxygenase activity (7.6%) flavin adenine dinucleotide binding (7.6%)" "IPR005337 (10.6%) IPR053931 (10.6%) IPR002575 (10.1%)" "RapZ-like family (10.6%) RapZ, C-terminal domain (10.6%) Aminoglycoside phosphotransferase (10.1%)" GQWHTAVPPQAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (50%) GO:0016788 (47.1%) GO:0016787 (2.9%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (47.1%) hydrolase activity (2.9%)" "IPR000801 (17.2%) IPR005181 (17.2%) IPR050583 (17.2%)" "Esterase-like (17.2%) Sialate O-acetylesterase domain (17.2%) Mycobacterial A85 antigen (17.2%)" FACLDVTLGPKDEDYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20.4%) GO:0005737 (19.5%) "GO:0003746 (20.4%) GO:0005525 (20.4%) GO:0003924 (19.5%)" ribosome disassembly (20.4%) cytoplasm (19.5%) "translation elongation factor activity (20.4%) GTP binding (20.4%) GTPase activity (19.5%)" "IPR000640 (6.4%) IPR004161 (6.4%) IPR005517 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%) Translation elongation factor EFG/EF2, domain IV (6.4%)" GMSNVLAMLNPNDLESFTVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" GKLNAVLTGVGGYVPDYLLNNEELSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (20%)" GO:0005737 (20%) "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (20%)" cytoplasm (20%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" TDALMLSGETASGK root 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (4.2%) "GO:0000287 (19.2%) GO:0004743 (19.2%) GO:0016301 (19.2%)" response to stress (4.2%) "magnesium ion binding (19.2%) pyruvate kinase activity (19.2%) kinase activity (19.2%)" "IPR001697 (11.2%) IPR015793 (11.2%) IPR015795 (11.1%)" "Pyruvate kinase (11.2%) Pyruvate kinase, barrel (11.2%) Pyruvate kinase, C-terminal (11.1%)" LGLSGVATQLYSWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR011579 (33.3%) IPR027417 (33.3%) IPR036390 (33.3%)" "ATPase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) Winged helix DNA-binding domain superfamily (33.3%)" VEAATQTFATLTLQNYFR Bacteroidota Bacteria Pseudomonadati Bacteroidota 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005886 (11.1%) GO:0031522 (11.1%) GO:0005829 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (10.7%) GO:0004386 (0.2%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%) cytosol (11.1%)" "ATP binding (11.1%) metal ion binding (10.7%) helicase activity (0.2%)" "IPR000185 (7.8%) IPR011115 (7.8%) IPR014018 (7.8%)" "Protein translocase subunit SecA (7.8%) SecA DEAD-like, N-terminal (7.8%) SecA motor DEAD (7.8%)" GLHYTLDYPVHAYDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (34.2%) GO:0005737 (31.5%) GO:0008734 (34.2%) 'de novo' NAD+ biosynthetic process from L-aspartate (34.2%) cytoplasm (31.5%) L-aspartate oxidase activity (34.2%) "IPR005288 (17.4%) IPR015939 (17.4%) IPR003953 (16.7%)" "L-aspartate oxidase (17.4%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (17.4%) FAD-dependent oxidoreductase 2, FAD-binding domain (16.7%)" GGLGYLCYNVPEGQYLLGDNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" WNDSSCYSLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011250 (50%) IPR027385 (50%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (50%) Outer membrane protein, beta-barrel domain (50%)" MHFSSVYGVNVTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.1%) IPR006512 (25.1%) IPR050144 (25.1%)" "Regulator of K+ conductance, C-terminal (25.1%) YidE/YbjL duplication (25.1%) AAE Transporter (25.1%)" ELVSWLLR root "1.2.1.65 (66.7%) 1.2.1.3 (16.7%) 6.3.2.4 (16.7%)" "salicylaldehyde dehydrogenase (66.7%) aldehyde dehydrogenase (NAD(+)) (16.7%) D-alanine--D-alanine ligase (16.7%)" "GO:0008360 (1.9%) GO:0009252 (1.9%) GO:0042364 (1.9%)" "GO:0016020 (1.9%) GO:0005737 (1.3%) GO:0005886 (1.3%)" "GO:0046872 (24.5%) GO:0016787 (22%) GO:0016620 (5%)" "regulation of cell shape (1.9%) peptidoglycan biosynthetic process (1.9%) water-soluble vitamin biosynthetic process (1.9%)" "membrane (1.9%) cytoplasm (1.3%) plasma membrane (1.3%)" "metal ion binding (24.5%) hydrolase activity (22%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (5%)" "IPR039461 (17.8%) IPR015590 (4.5%) IPR016161 (4.5%)" "Peptidase family M49 (17.8%) Aldehyde dehydrogenase domain (4.5%) Aldehyde/histidinol dehydrogenase (4.5%)" MQAVVNLYYALGGGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" VADNFYLGPMASYDYVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (100%) outer membrane (100%) "IPR000184 (73.2%) IPR036709 (26.8%)" "Bacterial surface antigen (D15) (73.2%) Autotransporter beta-domain superfamily (26.8%)" RANNFQNEVCWER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" AAEVFGELLTLVEGGQTQYGLAEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.5%) IPR011990 (32.3%) IPR012944 (32.3%)" "SusD-like, N-terminal (35.5%) Tetratricopeptide-like helical domain superfamily (32.3%) RagB/SusD domain (32.3%)" AHPEYYPDDVKVPTETDPGDHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FDEEYNLGDTLTVELFNDCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000597 (24.2%) IPR009000 (24.2%) IPR019926 (24.2%)" "Large ribosomal subunit protein uL3 (24.2%) Translation protein, beta-barrel domain superfamily (24.2%) Large ribosomal subunit protein uL3, conserved site (24.2%)" SDYDAWLDELYKNPLVGDDLGGGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR009387 (100%) Toxin HigB-2 (100%) VDPNASLMVYVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (57.1%) "GO:0016787 (21.4%) GO:0016829 (21.4%)" carbohydrate metabolic process (57.1%) "hydrolase activity (21.4%) lyase activity (21.4%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" YLVLMPFGDKVSVSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.5%) IPR004659 (25.5%) IPR019307 (25.5%)" "S1 domain (25.5%) Ribonuclease E/G (25.5%) RNA-binding protein AU-1/Ribonuclease E/G (25.5%)" ENYSYQLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae VADGNYAVCVTPGTTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR051200 (41.2%) IPR015943 (35.3%) IPR011044 (23.5%)" "Multi-functional host-pathogen interaction and enzymatic activity protein (41.2%) WD40/YVTN repeat-like-containing domain superfamily (35.3%) Quinoprotein amine dehydrogenase, beta chain-like (23.5%)" LSELMRPLLSFNEDESLYQLWEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) "IPR002550 (25.7%) IPR000644 (24.8%) IPR044751 (24.8%)" "CNNM, transmembrane domain (25.7%) CBS domain (24.8%) Ion transporter-like, CBS domain (24.8%)" NNCLVQLVTSSPLSPWPDLMQGYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.- (100%) Transferases for other substituted phosphate groups (100%) GO:0032049 (32.8%) GO:0005886 (32.8%) "GO:0008808 (32.8%) GO:0016787 (1.6%)" cardiolipin biosynthetic process (32.8%) plasma membrane (32.8%) "cardiolipin synthase activity (32.8%) hydrolase activity (1.6%)" "IPR001736 (20%) IPR022924 (20%) IPR025202 (20%)" "Phospholipase D/Transphosphatidylase (20%) Cardiolipin synthase (20%) Phospholipase D-like domain (20%)" TTTYNGGLDFTALNGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (14.3%) IPR023996 (14.3%) IPR039426 (14.3%)" "TonB-dependent receptor-like, beta-barrel (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent receptor-like (14.3%)" AADREGVELNTYSLLYDALDDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (25.5%) "GO:0003743 (25.5%) GO:0005525 (25.5%) GO:0003924 (23.6%)" cytoplasm (25.5%) "translation initiation factor activity (25.5%) GTP binding (25.5%) GTPase activity (23.6%)" "IPR004161 (8.8%) IPR015760 (8.8%) IPR009000 (8.5%)" "Translation elongation factor EFTu-like, domain 2 (8.8%) Translation initiation factor IF- 2 (8.8%) Translation protein, beta-barrel domain superfamily (8.5%)" TDLLWQLANR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR018631 (51.7%) IPR012547 (48.3%)" "AAA-ATPase-like domain (51.7%) PD-(D/E)XK nuclease superfamily 9 (48.3%)" ALPKVEGLDGNYYGLLYLPAGGEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" VLVPDADEQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.1.1.199 (91.7%) 2.1.1.- (8.3%)" "16S rRNA (cytosine(1402)-N(4))-methyltransferase (91.7%) Methyltransferases (8.3%)" "GO:0070475 (31.4%) GO:0032259 (2.9%)" GO:0005737 (31.4%) "GO:0071424 (31.4%) GO:0008168 (2.9%)" "rRNA base methylation (31.4%) methylation (2.9%)" cytoplasm (31.4%) "rRNA (cytosine-N4-)-methyltransferase activity (31.4%) methyltransferase activity (2.9%)" "IPR002903 (34.3%) IPR029063 (34.3%) IPR023397 (31.4%)" "Ribosomal RNA small subunit methyltransferase H (34.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (34.3%) S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily (31.4%)" SNYYASLSAMVDPGWYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" LNNELGNTEGQLESYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (17.7%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (17.7%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" SDDLFEDALRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (32.3%) "GO:0005525 (32.3%) GO:0043022 (32.3%) GO:0016787 (3.2%)" ribosome biogenesis (32.3%) "GTP binding (32.3%) ribosome binding (32.3%) hydrolase activity (3.2%)" "IPR005225 (14.4%) IPR006073 (14.4%) IPR016484 (14.4%)" "Small GTP-binding domain (14.4%) GTP binding domain (14.4%) GTPase Der (14.4%)" TMVLTDDAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.8%) IPR029483 (14.8%) IPR029486 (14.8%)" "Glycosyl-hydrolase 97, catalytic domain (14.8%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.8%) Glycosyl-hydrolase 97, N-terminal domain (14.8%)" TPTMGNLQLYSVVVTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.5.1.39 (60%) 1.5.1.- (40%)" "FMN reductase [NAD(P)H] (60%) With NAD(+) or NADP(+) as acceptor (40%)" "GO:0016491 (95.3%) GO:0008752 (4.7%)" "oxidoreductase activity (95.3%) FMN reductase [NAD(P)H] activity (4.7%)" "IPR016446 (33.9%) IPR029479 (33.9%) IPR000415 (32.3%)" "Flavin oxidoreductase Frp family (33.9%) Nitroreductase (33.9%) Nitroreductase-like (32.3%)" TVCYTASSSDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (20.3%) IPR002469 (20.3%) IPR011659 (20.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (20.3%) Dipeptidylpeptidase IV, N-terminal domain (20.3%) WD40-like beta-propeller (20.3%)" LSQHLGLLPLLLVSPSDVSLLEGGSEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000731 (14.2%) GO:0006260 (14.2%) GO:0006302 (14.2%)" "GO:0005737 (14.2%) GO:0016020 (0.8%)" "GO:0003697 (14.2%) GO:0005524 (14.2%)" "DNA synthesis involved in DNA repair (14.2%) DNA replication (14.2%) double-strand break repair (14.2%)" "cytoplasm (14.2%) membrane (0.8%)" "single-stranded DNA binding (14.2%) ATP binding (14.2%)" "IPR001238 (20.9%) IPR003395 (20.9%) IPR018078 (20.9%)" "DNA-binding, RecF (20.9%) RecF/RecN/SMC, N-terminal (20.9%) DNA-binding, RecF, conserved site (20.9%)" GHLEAMTLNTFAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25%) IPR006512 (25%) IPR036721 (25%)" "Regulator of K+ conductance, C-terminal (25%) YidE/YbjL duplication (25%) Regulator of K+ conductance, C-terminal domain superfamily (25%)" YQLELATLR root GO:0016020 (78.9%) "GO:0005524 (10.5%) GO:0016887 (10.5%)" membrane (78.9%) "ATP binding (10.5%) ATP hydrolysis activity (10.5%)" "IPR007060 (66.7%) IPR003959 (11.1%) IPR027417 (11.1%)" "Septum formation initiator FtsL/DivIC (66.7%) ATPase, AAA-type, core (11.1%) P-loop containing nucleoside triphosphate hydrolase (11.1%)" VSDFLLSLK Pseudomonadati Bacteria Pseudomonadati "3.2.1.78 (83.9%) 6.3.2.12 (6.5%) 6.3.2.17 (6.5%)" "mannan endo-1,4-beta-mannosidase (83.9%) dihydrofolate synthase (6.5%) tetrahydrofolate synthase (6.5%)" "GO:0006080 (32.5%) GO:0046656 (1.6%) GO:0006400 (0.8%)" "GO:0005576 (21.1%) GO:0005737 (2.4%) GO:0042597 (0.8%)" "GO:0016985 (32.5%) GO:0005524 (2.4%) GO:0004326 (1.6%)" "substituted mannan metabolic process (32.5%) folic acid biosynthetic process (1.6%) tRNA modification (0.8%)" "extracellular region (21.1%) cytoplasm (2.4%) periplasmic space (0.8%)" "mannan endo-1,4-beta-mannosidase activity (32.5%) ATP binding (2.4%) tetrahydrofolylpolyglutamate synthase activity (1.6%)" "IPR000805 (23.3%) IPR022790 (23.3%) IPR017853 (22.1%)" "Glycoside hydrolase family 26 (23.3%) Glycosyl hydrolase family 26 domain (23.3%) Glycoside hydrolase superfamily (22.1%)" LNLQGNLLGTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (80%) IPR011044 (20%)" "WD40/YVTN repeat-like-containing domain superfamily (80%) Quinoprotein amine dehydrogenase, beta chain-like (20%)" DKETEDLTVVSLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) "GO:0016757 (96.6%) GO:0016740 (3.4%)" "glycosyltransferase activity (96.6%) transferase activity (3.4%)" IPR028098 (100%) Glycosyltransferase subfamily 4-like, N-terminal domain (100%) QFVLTGNYPYDLSSQLFFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.182 (98.9%) 2.1.1.- (1.1%)" "16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (98.9%) Methyltransferases (1.1%)" GO:0005829 (33.3%) "GO:0003723 (33.3%) GO:0052908 (21%) GO:0000179 (12.4%)" cytosol (33.3%) "RNA binding (33.3%) 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity (21%) rRNA (adenine-N6,N6-)-dimethyltransferase activity (12.4%)" "IPR001737 (16.7%) IPR011530 (16.7%) IPR020596 (16.7%)" "Ribosomal RNA adenine methyltransferase KsgA/Erm (16.7%) Ribosomal RNA adenine dimethylase (16.7%) Ribosomal RNA adenine methylase transferase, conserved site (16.7%)" TLLTPEQLENEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009228 (25%) "GO:0003824 (25%) GO:0005506 (25%) GO:0051539 (25%)" thiamine biosynthetic process (25%) "catalytic activity (25%) iron ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR007197 (20.2%) IPR010722 (20.2%) IPR012726 (20.2%)" "Radical SAM (20.2%) Biotin and thiamin synthesis-associated domain (20.2%) Thiazole biosynthesis ThiH (20.2%)" NALEFLLEHYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.5%) GO:0034605 (12.5%)" GO:0005737 (12.5%) "GO:0004176 (12.5%) GO:0004252 (12.5%) GO:0005524 (12.5%)" "protein quality control for misfolded or incompletely synthesized proteins (12.5%) cellular response to heat (12.5%)" cytoplasm (12.5%) "ATP-dependent peptidase activity (12.5%) serine-type endopeptidase activity (12.5%) ATP binding (12.5%)" "IPR003111 (7.4%) IPR003593 (7.4%) IPR003959 (7.4%)" "Lon protease, N-terminal domain (7.4%) AAA+ ATPase domain (7.4%) ATPase, AAA-type, core (7.4%)" EMSEDKLSAYQTLYTCLMTVAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" SNGFYTVFDAATGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (46.2%) GO:0009279 (53.8%) iron ion transport (46.2%) cell outer membrane (53.8%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GSSGQPGSDNNGVNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" AFVDYYK root "4.1.1.65 (50%) 1.14.13.2 (25%) 4.1.99.- (25%)" "phosphatidylserine decarboxylase (50%) 4-hydroxybenzoate 3-monooxygenase (25%) Other carbon-carbon lyases (25%)" "GO:0042026 (10.5%) GO:0010024 (9.9%) GO:0006457 (4.5%)" "GO:0005737 (10.5%) GO:0016020 (2.5%) GO:0005783 (1%)" "GO:0051082 (15%) GO:0050897 (9.9%) GO:0050619 (8.6%)" "protein refolding (10.5%) phytochromobilin biosynthetic process (9.9%) protein folding (4.5%)" "cytoplasm (10.5%) membrane (2.5%) endoplasmic reticulum (1%)" "unfolded protein binding (15%) cobalt ion binding (9.9%) phytochromobilin:ferredoxin oxidoreductase activity (8.6%)" "IPR001623 (9.4%) IPR002939 (9.4%) IPR008971 (9.2%)" "DnaJ domain (9.4%) Chaperone DnaJ, C-terminal (9.4%) HSP40/DnaJ peptide-binding (9.2%)" FYVDALAR root "GO:0008360 (10.5%) GO:0009252 (10.5%) GO:0071555 (10.5%)" "GO:0005739 (4.8%) GO:0005948 (4.8%) GO:0016020 (0.3%)" "GO:0016740 (10.5%) GO:0004180 (9.6%) GO:0000287 (5.1%)" "regulation of cell shape (10.5%) peptidoglycan biosynthetic process (10.5%) cell wall organization (10.5%)" "mitochondrion (4.8%) acetolactate synthase complex (4.8%) membrane (0.3%)" "transferase activity (10.5%) carboxypeptidase activity (9.6%) magnesium ion binding (5.1%)" "IPR005490 (13.4%) IPR045380 (13.4%) IPR052905 (13.4%)" "L,D-transpeptidase catalytic domain (13.4%) L,D-transpeptidase, scaffold domain (13.4%) L,D-transpeptidase YkuD-like (13.4%)" WSADDQSLYDTWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.3%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" AGPALQNTLLTVLNEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) GO:0016020 (6.3%) "GO:0005524 (70.8%) GO:0016787 (20.8%) GO:0016887 (2.1%)" membrane (6.3%) "ATP binding (70.8%) hydrolase activity (20.8%) ATP hydrolysis activity (2.1%)" "IPR045427 (19%) IPR050513 (19%) IPR041538 (18.6%)" "MoxR domain (19%) RavA family ATPases (19%) ATPase RavA-like, AAA lid domain (18.6%)" AGELVSYELDQAFFALYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" HDFAMQLQLQPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) MFYSATAYNPTYPNVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TLSETVDMDVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (30.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (30.3%)" TWVAPEDAGKAEVPAGYSTLLDGAGWAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NHYNEMEVNLNQAASKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (51.4%) GO:0030246 (48.6%)" "hydrolase activity (51.4%) carbohydrate binding (48.6%)" "IPR019563 (15%) IPR029483 (15%) IPR029486 (15%)" "Glycosyl-hydrolase 97, catalytic domain (15%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (15%) Glycosyl-hydrolase 97, N-terminal domain (15%)" TLLTVVGK root "5.3.4.1 (50%) 2.7.10.1 (33.3%) 5.6.2.1 (16.7%)" "protein disulfide-isomerase (50%) receptor protein-tyrosine kinase (33.3%) DNA topoisomerase (16.7%)" "GO:0006457 (2.4%) GO:0030334 (2.4%) GO:0034976 (2.4%)" "GO:0016020 (30.1%) GO:0002116 (2.4%) GO:0005788 (2.4%)" "GO:0022857 (26%) GO:0003756 (2.4%) GO:0005524 (2.4%)" "protein folding (2.4%) regulation of cell migration (2.4%) response to endoplasmic reticulum stress (2.4%)" "membrane (30.1%) semaphorin receptor complex (2.4%) endoplasmic reticulum lumen (2.4%)" "transmembrane transporter activity (26%) protein disulfide isomerase activity (2.4%) ATP binding (2.4%)" "IPR002912 (17.6%) IPR022986 (17.6%) IPR050990 (17.6%)" "ACT domain (17.6%) Uncharacterised protein family UPF0237, ACT-type (17.6%) UPF0237/Glycine cleavage system regulator (17.6%)" KMPSALLAGLFNFNVMPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" AHSLEAQALWSDTMSMVEETLGGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (22.1%) GO:0016020 (2.9%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (22.1%) membrane (2.9%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.8%) IPR003593 (14.8%) IPR011527 (14.8%)" "ABC transporter-like, ATP-binding domain (14.8%) AAA+ ATPase domain (14.8%) ABC transporter type 1, transmembrane domain (14.8%)" VLLDNQYPGLLYQDQLFQYLHTGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR014464 (20.7%) IPR040764 (20.7%) IPR039566 (20%)" "Conserved virulence factor B (20.7%) Conserved virulence factor B-like, winged helix domain (20.7%) Conserved virulence factor B, first S1 domain (20%)" QALFPLGQHLGAPAKPVVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) GO:0022900 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0046872 (20%) GO:0051539 (20%)" electron transport chain (20%) plasma membrane (20%) "electron transfer activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR010208 (14.4%) IPR011538 (14.4%) IPR017896 (14.4%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.4%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" YTLQGMRPGGPYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (17.2%) IPR057601 (17.2%) IPR008969 (16.6%)" "TonB-dependent receptor-like (17.2%) TonB-dependent transporter Oar-like, beta-barrel domain (17.2%) Carboxypeptidase-like, regulatory domain superfamily (16.6%)" TFMGLEPVLAEELTQLGANNVQLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.8%) IPR002052 (16.8%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) DNA methylase, N-6 adenine-specific, conserved site (16.8%) THUMP domain (16.8%)" LPLSTTYVTFMVAMGSSLADR Pseudomonadati Bacteria Pseudomonadati GO:0035435 (33.2%) GO:0016020 (33.7%) GO:0005315 (33.2%) phosphate ion transmembrane transport (33.2%) membrane (33.7%) phosphate transmembrane transporter activity (33.2%) "IPR001204 (91%) IPR038078 (9%)" "Phosphate transporter (91%) PhoU-like domain superfamily (9%)" FENLSDRLER Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20%) "GO:0048500 (19.5%) GO:0005786 (0.5%)" "GO:0003924 (20%) GO:0005525 (20%) GO:0008312 (19.9%)" SRP-dependent cotranslational protein targeting to membrane (20%) "signal recognition particle (19.5%) signal recognition particle, endoplasmic reticulum targeting (0.5%)" "GTPase activity (20%) GTP binding (20%) 7S RNA binding (19.9%)" "IPR013822 (11.2%) IPR022941 (11.2%) IPR042101 (11.2%)" "Signal recognition particle SRP54, helical bundle (11.2%) Signal recognition particle, SRP54 subunit (11.2%) Signal recognition particle SRP54, N-terminal domain superfamily (11.2%)" YTWLDPANGNNLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (42.9%) GO:0009279 (57.1%) iron ion transport (42.9%) cell outer membrane (57.1%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" WSEESPLK root 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (7.9%) IPR002547 (7.7%) IPR004532 (7.7%)" "Phenylalanyl tRNA synthetase beta chain, core domain (7.9%) tRNA-binding domain (7.7%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.7%)" LVASLSDR root "2.7.1.40 (88.4%) 5.3.1.6 (2.7%) 1.14.11.67 (2%)" "pyruvate kinase (88.4%) ribose-5-phosphate isomerase (2.7%) [histone H3]-trimethyl-L-lysine(4) demethylase (2%)" "GO:0006950 (7.7%) GO:0006355 (0.4%) GO:0006457 (0.4%)" "GO:0016020 (1.3%) GO:0005886 (1.1%) GO:0005829 (0.8%)" "GO:0005524 (14%) GO:0000287 (13.3%) GO:0004743 (13.3%)" "response to stress (7.7%) regulation of DNA-templated transcription (0.4%) protein folding (0.4%)" "membrane (1.3%) plasma membrane (1.1%) cytosol (0.8%)" "ATP binding (14%) magnesium ion binding (13.3%) pyruvate kinase activity (13.3%)" "IPR001697 (8.6%) IPR015793 (8.6%) IPR018209 (8.5%)" "Pyruvate kinase (8.6%) Pyruvate kinase, barrel (8.6%) Pyruvate kinase, active site (8.5%)" QTLNADNLK root GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" ELCLLSK root "6.1.1.6 (36.1%) 2.7.11.1 (18.1%) 2.3.2.31 (4.2%)" "lysine--tRNA ligase (36.1%) non-specific serine/threonine protein kinase (18.1%) RBR-type E3 ubiquitin transferase (4.2%)" "GO:0046599 (2.5%) GO:0006430 (2.3%) GO:0015074 (2.1%)" "GO:0005829 (5.1%) GO:0016020 (3%) GO:0005813 (2.5%)" "GO:0005524 (7.1%) GO:0000287 (2.6%) GO:0008017 (2.5%)" "regulation of centriole replication (2.5%) lysyl-tRNA aminoacylation (2.3%) DNA integration (2.1%)" "cytosol (5.1%) membrane (3%) centrosome (2.5%)" "ATP binding (7.1%) magnesium ion binding (2.6%) microtubule binding (2.5%)" "IPR011009 (2%) IPR000719 (1.9%) IPR013783 (1.8%)" "Protein kinase-like domain superfamily (2%) Protein kinase domain (1.9%) Immunoglobulin-like fold (1.8%)" SETGENWLTYHHNWFDHSDSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000272 (30%) GO:0005576 (30%) "GO:0030570 (30%) GO:0004557 (10%)" polysaccharide catabolic process (30%) extracellular region (30%) "pectate lyase activity (30%) alpha-galactosidase activity (10%)" "IPR002022 (18.2%) IPR011050 (18.2%) IPR012334 (18.2%)" "Pectate lyase (18.2%) Pectin lyase fold/virulence factor (18.2%) Pectin lyase fold (18.2%)" SFYEAGKPVYCLYVALGQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (18.8%) GO:0005886 (18.2%)" "GO:0005524 (18.8%) GO:0043531 (18.8%) GO:0046933 (18.8%)" "proton-transporting ATP synthase complex (18.8%) plasma membrane (18.2%)" "ATP binding (18.8%) ADP binding (18.8%) proton-transporting ATP synthase activity, rotational mechanism (18.8%)" "IPR000194 (10.2%) IPR005294 (10.2%) IPR027417 (10.2%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.2%) ATP synthase, F1 complex, alpha subunit (10.2%) P-loop containing nucleoside triphosphate hydrolase (10.2%)" LLQMYESMKPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.3.1.191 (96.6%) 2.3.1.- (3.4%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (96.6%) Transferring groups other than amino-acyl groups (3.4%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20%) IPR007691 (20%) IPR011004 (20%)" "Hexapeptide repeat (20%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20%) Trimeric LpxA-like superfamily (20%)" GGASHVAEMPFLYGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0016787 (97.1%) GO:0052689 (2.9%)" "hydrolase activity (97.1%) carboxylic ester hydrolase activity (2.9%)" "IPR002018 (20.6%) IPR019826 (20%) IPR050309 (20%)" "Carboxylesterase, type B (20.6%) Carboxylesterase type B, active site (20%) Type-B Carboxylesterase/Lipase (20%)" KANPDLLLFDSGDFSQGSPYYSLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009166 (25%) "GO:0000166 (25%) GO:0016788 (25%) GO:0046872 (25%)" nucleotide catabolic process (25%) "nucleotide binding (25%) hydrolase activity, acting on ester bonds (25%) metal ion binding (25%)" "IPR004843 (25.2%) IPR006146 (25.2%) IPR006179 (25.2%)" "Calcineurin-like, phosphoesterase domain (25.2%) 5'-Nucleotidase, conserved site (25.2%) 5'-Nucleotidase/apyrase (25.2%)" AGLLTPEMEYVALR root 4.1.99.17 (100%) phosphomethylpyrimidine synthase (100%) "GO:0009228 (16.7%) GO:0009229 (16.5%)" GO:0005829 (16.7%) "GO:0051539 (16.7%) GO:0008270 (16.5%) GO:0070284 (11.7%)" "thiamine biosynthetic process (16.7%) thiamine diphosphate biosynthetic process (16.5%)" cytosol (16.7%) "4 iron, 4 sulfur cluster binding (16.7%) zinc ion binding (16.5%) phosphomethylpyrimidine synthase activity (11.7%)" "IPR002817 (25%) IPR025747 (25%) IPR037509 (25%)" "Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B (25%) ThiC-associated domain (25%) Phosphomethylpyrimidine synthase (25%)" LNHVLTPGK Bacteria Bacteria "2.4.-.- (66.7%) 2.4.1.52 (33.3%)" "Glycosyltransferases (66.7%) poly(glycerol-phosphate) alpha-glucosyltransferase (33.3%)" "GO:0016757 (75%) GO:0047265 (25%)" "glycosyltransferase activity (75%) poly(glycerol-phosphate) alpha-glucosyltransferase activity (25%)" IPR001296 (100%) Glycosyl transferase, family 1 (100%) DLTTTAQFLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0004822 (14.3%) GO:0005524 (14.3%)" isoleucyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) isoleucine-tRNA ligase activity (14.3%) ATP binding (14.3%)" "IPR002300 (12.6%) IPR002301 (12.6%) IPR013155 (12.6%)" "Aminoacyl-tRNA synthetase, class Ia (12.6%) Isoleucine-tRNA ligase (12.6%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.6%)" SQHEEELAVECGYWHLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.9%) GO:0022900 (14.1%) GO:0044281 (13.4%)" "GO:0030976 (14.5%) GO:0005506 (14.1%) GO:0051539 (14.1%)" "response to oxidative stress (14.9%) electron transport chain (14.1%) small molecule metabolic process (13.4%)" "thiamine pyrophosphate binding (14.5%) iron ion binding (14.1%) 4 iron, 4 sulfur cluster binding (14.1%)" "IPR050722 (8.1%) IPR011766 (7.9%) IPR029061 (7.9%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Thiamin diphosphate-binding fold (7.9%)" EGFDQVMYLNADK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.1.3.3 (96.9%) 5.1.3.- (3.1%)" "aldose 1-epimerase (96.9%) Acting on carbohydrates and derivatives (3.1%)" "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19%)" "IPR008183 (17.2%) IPR018052 (17.2%) IPR047215 (17.2%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.2%) Aldose 1-epimerase, conserved site (17.2%) Galactose mutarotase-like (17.2%)" REFSYSSYSQSYALPEDADQEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (33.3%) IPR008978 (33.3%) IPR031107 (33.3%)" "Alpha crystallin/Hsp20 domain (33.3%) HSP20-like chaperone (33.3%) Small heat shock protein (33.3%)" RSNVTYLVQAK Pseudomonadati Bacteria Pseudomonadati IPR027848 (100%) Protein of unknown function DUF4494 (100%) CDMVDDEEMLELVEMELR Bacteria Bacteria 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (16.7%) GO:0032045 (10%)" "GO:0003746 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" "cytosol (16.7%) guanyl-nucleotide exchange factor complex (10%)" "translation elongation factor activity (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" LFHAAATTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.7%) GO:0004560 (51.3%) carbohydrate metabolic process (48.7%) alpha-L-fucosidase activity (51.3%) "IPR027414 (17.1%) IPR049053 (17.1%) IPR054363 (17.1%)" "Glycosyl hydrolase family 95, N-terminal domain (17.1%) Alpha fucosidase A-like, C-terminal domain (17.1%) Glycosyl hydrolase family 95, catalytic domain (17.1%)" YPAMNCYDFLHLYVPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.78 (100%) mannan endo-1,4-beta-mannosidase (100%) "GO:0006080 (24.4%) GO:0000272 (23.3%) GO:0030245 (6.7%)" "GO:0005576 (6.7%) GO:0009986 (6.7%)" "GO:0016985 (24.4%) GO:0008422 (6.7%) GO:0004553 (1.1%)" "substituted mannan metabolic process (24.4%) polysaccharide catabolic process (23.3%) cellulose catabolic process (6.7%)" "extracellular region (6.7%) cell surface (6.7%)" "mannan endo-1,4-beta-mannosidase activity (24.4%) beta-glucosidase activity (6.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.1%)" "IPR022790 (26.1%) IPR001547 (24.3%) IPR017853 (24.3%)" "Glycosyl hydrolase family 26 domain (26.1%) Glycoside hydrolase, family 5 (24.3%) Glycoside hydrolase superfamily (24.3%)" TFSAQMLK root GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" EGFEHEFDLDALRDDWYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" NLVWLNTPFSLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KLLATSNDPAEAYEAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005737 (20%) GO:0015935 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "cytoplasm (20%) small ribosomal subunit (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR001209 (33.3%) IPR018271 (33.3%) IPR023036 (33.3%)" "Small ribosomal subunit protein uS14 (33.3%) Small ribosomal subunit protein uS14, conserved site (33.3%) Small ribosomal subunit protein uS14, bacteria/plastid (33.3%)" DYEGLCTAGFSPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005976 (50%) GO:0052689 (50%) polysaccharide metabolic process (50%) carboxylic ester hydrolase activity (50%) "IPR008391 (34%) IPR039069 (34%) IPR029058 (32.1%)" "Acetyl xylan esterase domain (34%) Carbohydrate esterase 7 family (34%) Alpha/Beta hydrolase fold (32.1%)" CENLSVAYTFPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (20%) GO:0009279 (80%) iron ion transport (20%) cell outer membrane (80%) "IPR000531 (13.6%) IPR039426 (13.6%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (13.6%) TonB-dependent receptor-like (13.6%) TonB-dependent receptor, plug domain (12.5%)" LMLADQSADLHCTDTYQWPTANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (12.5%) IPR002772 (12.5%) IPR013783 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (12.5%) Glycoside hydrolase family 3 C-terminal domain (12.5%) Immunoglobulin-like fold (12.5%)" VGSDVPTVK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.6%) GO:0006164 (0.7%)" GO:0005737 (20.3%) "GO:0004642 (20.3%) GO:0005524 (19.6%) GO:0046872 (19.6%)" "'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.7%)" cytoplasm (20.3%) "phosphoribosylformylglycinamidine synthase activity (20.3%) ATP binding (19.6%) metal ion binding (19.6%)" "IPR010918 (11.4%) IPR055181 (11.4%) IPR010073 (11.1%)" "PurM-like, C-terminal domain (11.4%) FGAR-AT, PurM N-terminal-like domain (11.4%) Phosphoribosylformylglycinamidine synthase PurL (11.1%)" DLDWSVSLNMSHNSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QYLEAGDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0034605 (24.7%) GO:0006508 (0.6%)" GO:0005737 (24.7%) "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0008233 (0.6%)" "cellular response to heat (24.7%) proteolysis (0.6%)" cytoplasm (24.7%) "ATP binding (24.7%) ATP hydrolysis activity (24.7%) peptidase activity (0.6%)" "IPR003593 (10.3%) IPR003959 (10.3%) IPR019489 (10.3%)" "AAA+ ATPase domain (10.3%) ATPase, AAA-type, core (10.3%) Clp ATPase, C-terminal (10.3%)" VMAADYAHFVNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) IPR011009 (100%) Protein kinase-like domain superfamily (100%) DSELAYLK root "3.4.11.- (42.9%) 5.6.2.4 (28.6%) 2.7.11.1 (14.3%)" "Aminopeptidases (42.9%) DNA 3'-5' helicase (28.6%) non-specific serine/threonine protein kinase (14.3%)" "GO:0006629 (16.8%) GO:0006508 (2.4%) GO:0030968 (2.4%)" "GO:0005737 (3.2%) GO:0016020 (3.2%) GO:0005634 (2.4%)" "GO:0008081 (16.8%) GO:0005524 (5.6%) GO:0008270 (4%)" "lipid metabolic process (16.8%) proteolysis (2.4%) endoplasmic reticulum unfolded protein response (2.4%)" "cytoplasm (3.2%) membrane (3.2%) nucleus (2.4%)" "phosphoric diester hydrolase activity (16.8%) ATP binding (5.6%) zinc ion binding (4%)" "IPR017946 (11.5%) IPR030395 (11.5%) IPR024370 (10.4%)" "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily (11.5%) Glycerophosphodiester phosphodiesterase domain (11.5%) PBP domain (10.4%)" AALGLSQSSDALAVLVSEETGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.85 (100%) diadenylate cyclase (100%) GO:0006171 (20%) GO:0005886 (20%) "GO:0004016 (20%) GO:0005524 (20%) GO:0106408 (16.4%)" cAMP biosynthetic process (20%) plasma membrane (20%) "adenylate cyclase activity (20%) ATP binding (20%) diadenylate cyclase activity (16.4%)" "IPR003390 (16.7%) IPR014046 (16.7%) IPR034701 (16.7%)" "DNA integrity scanning protein, DisA, N-terminal (16.7%) Diadenylate cyclase (16.7%) Diadenylate cyclase CdaA (16.7%)" WETSEQLDLGLDAR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (13.6%) IPR036942 (13.6%) IPR039426 (13.6%)" "TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.6%) TonB-dependent receptor-like (13.6%)" LLLTVSGVGGNTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006281 (12%) GO:0006310 (12%)" "GO:0005737 (12%) GO:0009379 (12%) GO:0048476 (11.3%)" "GO:0005524 (12%) GO:0009378 (12%) GO:0000400 (11.3%)" "DNA repair (12%) DNA recombination (12%)" "cytoplasm (12%) Holliday junction helicase complex (12%) Holliday junction resolvase complex (11.3%)" "ATP binding (12%) four-way junction helicase activity (12%) four-way junction DNA binding (11.3%)" "IPR000085 (14.3%) IPR003583 (14.3%) IPR010994 (14.3%)" "Holliday junction branch migration complex subunit RuvA (14.3%) Helix-hairpin-helix DNA-binding motif, class 1 (14.3%) RuvA domain 2-like (14.3%)" LVELYEAALNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016627 (50%) GO:0050660 (50%)" "oxidoreductase activity, acting on the CH-CH group of donors (50%) flavin adenine dinucleotide binding (50%)" "IPR006091 (10%) IPR009075 (10%) IPR009100 (10%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (10%) Acyl-CoA dehydrogenase/oxidase, C-terminal (10%) Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily (10%)" NTSLGNSTDLLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri CNWCPSWNWGDDELFNPEADGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" GLDFSVTANGSVGNDLVQSYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" RAHLLFTDLDR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.4.1.1 (97.2%) 2.4.1.8 (2.8%)" "glycogen phosphorylase (97.2%) maltose phosphorylase (2.8%)" "GO:0005975 (32.8%) GO:0005978 (0.3%)" "GO:0030170 (33.1%) GO:0008184 (33%) GO:0004373 (0.3%)" "carbohydrate metabolic process (32.8%) glycogen biosynthetic process (0.3%)" "pyridoxal phosphate binding (33.1%) glycogen phosphorylase activity (33%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (0.3%)" "IPR011834 (25.1%) IPR052182 (25.1%) IPR000811 (25%)" "Alpha-glucan phosphorylase (25.1%) Glycogen_Maltodextrin_Phosphorylase (25.1%) Glycosyl transferase, family 35 (25%)" YLLLPDDTEEAFKAEMQLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) LGDYDVCPCLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.1 (50%) 6.1.1.7 (50%)" "alpha-amylase (50%) alanine--tRNA ligase (50%)" "GO:0043039 (17.7%) GO:0009313 (11.2%)" "GO:0005524 (17.7%) GO:0004812 (17.4%) GO:0046872 (17%)" "tRNA aminoacylation (17.7%) oligosaccharide catabolic process (11.2%)" "ATP binding (17.7%) aminoacyl-tRNA ligase activity (17.4%) metal ion binding (17%)" "IPR012947 (27.5%) IPR018163 (26.8%) IPR006047 (17.5%)" "Threonyl/alanyl tRNA synthetase, SAD (27.5%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (26.8%) Glycosyl hydrolase family 13, catalytic domain (17.5%)" TAAQQNHFLSAAGATEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" LVNEALLK root "2.2.1.9 (60.8%) 2.7.1.193 (3.9%) 3.2.1.58 (3.9%)" "2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (60.8%) protein-N(pi)-phosphohistidine--N-acetyl-D-glucosaminphosphotransferase (3.9%) glucan 1,3-beta-glucosidase (3.9%)" "GO:0009234 (8.3%) GO:0009401 (3.2%) GO:0015764 (1.1%)" "GO:0005886 (5.3%) GO:0016020 (1.9%) GO:0005730 (1.1%)" "GO:0030976 (8.6%) GO:0070204 (8.3%) GO:0000287 (8%)" "menaquinone biosynthetic process (8.3%) phosphoenolpyruvate-dependent sugar phosphotransferase system (3.2%) N-acetylglucosamine transport (1.1%)" "plasma membrane (5.3%) membrane (1.9%) nucleolus (1.1%)" "thiamine pyrophosphate binding (8.6%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (8.3%) magnesium ion binding (8%)" "IPR012001 (7.8%) IPR004433 (7.6%) IPR029061 (7.3%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (7.8%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (7.6%) Thiamin diphosphate-binding fold (7.3%)" NTANLLFK root "2.1.1.72 (50%) 3.6.1.11 (50%)" "site-specific DNA-methyltransferase (adenine-specific) (50%) exopolyphosphatase (50%)" "GO:0097272 (22.4%) GO:0034728 (2%) GO:0140673 (2%)" "GO:0005886 (23.1%) GO:0008023 (2%) GO:0000329 (0.7%)" "GO:0008519 (22.4%) GO:0003677 (2%) GO:0031491 (2%)" "ammonium homeostasis (22.4%) nucleosome organization (2%) transcription elongation-coupled chromatin remodeling (2%)" "plasma membrane (23.1%) transcription elongation factor complex (2%) fungal-type vacuole membrane (0.7%)" "ammonium channel activity (22.4%) DNA binding (2%) nucleosome binding (2%)" "IPR024041 (13.5%) IPR001905 (13.1%) IPR029020 (13.1%)" "Ammonium transporter AmtB-like domain (13.5%) Ammonium transporter (13.1%) Ammonium/urea transporter (13.1%)" QFTALADLHSVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009244 (32.9%) GO:0005829 (32.9%) "GO:0008713 (32.9%) GO:0016740 (1.3%)" lipopolysaccharide core region biosynthetic process (32.9%) cytosol (32.9%) "ADP-heptose-lipopolysaccharide heptosyltransferase activity (32.9%) transferase activity (1.3%)" "IPR051199 (51%) IPR002201 (49%)" "Lipopolysaccharide/Lipooligosaccharide Heptosyltransferase (51%) Glycosyl transferase, family 9 (49%)" NNGLEVSLTGSLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DGGMAFGVTCEGAASVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.3.-.- (94.1%) 1.3.1.14 (5.9%)" "Acting on the CH-CH group of donors (94.1%) dihydroorotate dehydrogenase (NAD(+)) (5.9%)" "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" LNLNAVR root "3.2.2.9 (58%) 3.2.1.23 (31.8%) 3.2.2.16 (4.1%)" "adenosylhomocysteine nucleosidase (58%) beta-galactosidase (31.8%) methylthioadenosine nucleosidase (4.1%)" "GO:0019284 (10.1%) GO:0019509 (10.1%) GO:0046124 (9.9%)" "GO:0005829 (10.2%) GO:0009341 (6.1%) GO:0005737 (0.6%)" "GO:0008782 (10.1%) GO:0008930 (10.1%) GO:0004565 (6.1%)" "L-methionine salvage from S-adenosylmethionine (10.1%) L-methionine salvage from methylthioadenosine (10.1%) purine deoxyribonucleoside catabolic process (9.9%)" "cytosol (10.2%) beta-galactosidase complex (6.1%) cytoplasm (0.6%)" "adenosylhomocysteine nucleosidase activity (10.1%) methylthioadenosine nucleosidase activity (10.1%) beta-galactosidase activity (6.1%)" "IPR000845 (7.5%) IPR010049 (7.5%) IPR035994 (7.5%)" "Nucleoside phosphorylase domain (7.5%) MTA/SAH nucleosidase (7.5%) Nucleoside phosphorylase superfamily (7.5%)" VSSSESTSSNMTFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) NVFGMNPLLAALQTAELAVNELGLKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (42.4%) GO:0005886 (44.1%) "GO:0016787 (11.9%) GO:0016301 (1.7%)" guanosine tetraphosphate metabolic process (42.4%) plasma membrane (44.1%) "hydrolase activity (11.9%) kinase activity (1.7%)" "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" TTPLVEMDGDEMTR Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.2%) GO:0006102 (20.2%) GO:0006739 (0.1%)" "GO:0004450 (20.2%) GO:0000287 (19%) GO:0051287 (19%)" "tricarboxylic acid cycle (20.2%) isocitrate metabolic process (20.2%) NADP+ metabolic process (0.1%)" "isocitrate dehydrogenase (NADP+) activity (20.2%) magnesium ion binding (19%) NAD binding (19%)" "IPR004790 (34%) IPR024084 (34%) IPR019818 (32%)" "Isocitrate dehydrogenase NADP-dependent (34%) Isopropylmalate dehydrogenase-like domain (34%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32%)" PFSVDFLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "1.2.7.1 (40%) 2.7.13.3 (40%) 1.2.-.- (20%)" "pyruvate synthase (40%) histidine kinase (40%) Acting on the aldehyde or oxo group of donors (20%)" "GO:0006979 (14.2%) GO:0022900 (13.9%) GO:0044281 (13.1%)" GO:0016020 (0.7%) "GO:0005506 (13.9%) GO:0030976 (13.9%) GO:0051539 (13.9%)" "response to oxidative stress (14.2%) electron transport chain (13.9%) small molecule metabolic process (13.1%)" membrane (0.7%) "iron ion binding (13.9%) thiamine pyrophosphate binding (13.9%) 4 iron, 4 sulfur cluster binding (13.9%)" "IPR002880 (7.4%) IPR033412 (7.4%) IPR050722 (7.4%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.4%) Pyruvate:ferredoxin oxidoreductase, core domain II (7.4%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.4%)" SYDELAMSGLTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" DAEVAQVNHMHNVCAGEPNYYVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.1%) "GO:0004556 (32.4%) GO:0043169 (32.4%)" carbohydrate metabolic process (35.1%) "alpha-amylase activity (32.4%) cation binding (32.4%)" "IPR006047 (17.6%) IPR031965 (17.6%) IPR006046 (16.2%)" "Glycosyl hydrolase family 13, catalytic domain (17.6%) Starch-binding module 26 (17.6%) Alpha amylase (16.2%)" AKNQELLDEGFLALFR Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.6%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.6%)" "IPR000185 (8.1%) IPR011115 (8.1%) IPR014001 (8.1%)" "Protein translocase subunit SecA (8.1%) SecA DEAD-like, N-terminal (8.1%) Helicase superfamily 1/2, ATP-binding domain (8.1%)" LETYKDFGGLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.4.11.9 (99%) 3.4.-.- (1%)" "Xaa-Pro aminopeptidase (99%) Acting on peptide bonds (peptidases) (1%)" GO:0006508 (25.1%) GO:0005829 (25.1%) "GO:0030145 (24.8%) GO:0070006 (24.8%) GO:0004177 (0.3%)" proteolysis (25.1%) cytosol (25.1%) "manganese ion binding (24.8%) metalloaminopeptidase activity (24.8%) aminopeptidase activity (0.3%)" "IPR000994 (20.2%) IPR052433 (20.2%) IPR007865 (20%)" "Peptidase M24 (20.2%) Xaa-Pro dipeptidase-like (20.2%) Aminopeptidase P, N-terminal (20%)" NDETPTFSTSGGWLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR024361 (50%)" "Immunoglobulin-like fold (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" LTHVNTYGWPTEAEALKDPYPENR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (50%) IPR012640 (33.3%) IPR013783 (16.7%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%) Membrane lipoprotein, lipid attachment site (33.3%) Immunoglobulin-like fold (16.7%)" HFAVNSQETDR Bacteria Bacteria 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (50%) "GO:0004553 (32.7%) GO:0008422 (17.3%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (32.7%) beta-glucosidase activity (17.3%)" "IPR001764 (12.1%) IPR050288 (12.1%) IPR002772 (11.8%)" "Glycoside hydrolase, family 3, N-terminal (12.1%) Cellulose-degrading glycosyl hydrolase 3 (12.1%) Glycoside hydrolase family 3 C-terminal domain (11.8%)" DGLSAAVDKVVELAQL Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.1%) GO:0005737 (14.1%) "GO:0000049 (14.5%) GO:0005524 (14.5%) GO:0002161 (14.1%)" alanyl-tRNA aminoacylation (14.1%) cytoplasm (14.1%) "tRNA binding (14.5%) ATP binding (14.5%) aminoacyl-tRNA deacylase activity (14.1%)" "IPR003156 (9.5%) IPR002318 (9.2%) IPR012947 (9.2%)" "DHHA1 domain (9.5%) Alanine-tRNA ligase, class IIc (9.2%) Threonyl/alanyl tRNA synthetase, SAD (9.2%)" ETYNYDDR Bacteria Bacteria GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR039426 (14.8%) IPR023996 (14.3%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent receptor-like (14.8%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TVEDLFTK root 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0015833 (6.1%) GO:0055085 (6.1%) GO:0006397 (3%)" "GO:0005886 (15.2%) GO:0000445 (3%) GO:0005829 (3%)" "GO:0003924 (12.1%) GO:0005525 (12.1%) GO:0005524 (9.1%)" "peptide transport (6.1%) transmembrane transport (6.1%) mRNA processing (3%)" "plasma membrane (15.2%) THO complex part of transcription export complex (3%) cytosol (3%)" "GTPase activity (12.1%) GTP binding (12.1%) ATP binding (9.1%)" "IPR027417 (13.7%) IPR001806 (7.8%) IPR005225 (7.8%)" "P-loop containing nucleoside triphosphate hydrolase (13.7%) Small GTPase (7.8%) Small GTP-binding domain (7.8%)" VVDFTLTPSYLVDDASATWSVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (42.4%) "GO:0052689 (42.4%) GO:0004557 (15.2%)" cell outer membrane (42.4%) "carboxylic ester hydrolase activity (42.4%) alpha-galactosidase activity (15.2%)" "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" MLEQGGLLTEFLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009294 (100%) DNA-mediated transformation (100%) "IPR003488 (49.3%) IPR057666 (49.3%) IPR036388 (1.4%)" "DNA recombination-mediator protein A (49.3%) Smf/DprA, SLOG domain (49.3%) Winged helix-like DNA-binding domain superfamily (1.4%)" AQLEAPYHDLTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.7%) GO:0009265 (16.7%)" GO:0031250 (16.7%) "GO:0004748 (16.7%) GO:0005524 (16.7%) GO:0008998 (16.7%)" "DNA replication (16.7%) 2'-deoxyribonucleotide biosynthetic process (16.7%)" anaerobic ribonucleoside-triphosphate reductase complex (16.7%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.7%) ATP binding (16.7%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.7%)" "IPR005144 (50%) IPR012833 (50%)" "ATP-cone domain (50%) Ribonucleoside-triphosphate reductase, anaerobic (50%)" QHNDANVLVLPGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.6 (100%) ribose-5-phosphate isomerase (100%) "GO:0009052 (33.3%) GO:0019316 (33.3%)" GO:0004751 (33.3%) "pentose-phosphate shunt, non-oxidative branch (33.3%) D-allose catabolic process (33.3%)" ribose-5-phosphate isomerase activity (33.3%) "IPR003500 (36.4%) IPR036569 (35.6%) IPR004785 (28%)" "Sugar-phosphate isomerase, RpiB/LacA/LacB family (36.4%) Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily (35.6%) Ribose 5-phosphate isomerase B (28%)" TNGADDWDLGLNQEADNFPPSLYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR011990 (33.3%) IPR033985 (30.3%)" "RagB/SusD domain (36.4%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (30.3%)" YFLNVGYYTQGGLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" WACDWCVESPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (24.7%) GO:0005737 (24.7%) "GO:0004134 (24.7%) GO:2001070 (24.7%) GO:0016740 (1.1%)" carbohydrate metabolic process (24.7%) cytoplasm (24.7%) "4-alpha-glucanotransferase activity (24.7%) starch binding (24.7%) transferase activity (1.1%)" "IPR002044 (21.1%) IPR003385 (21.1%) IPR013783 (19.3%)" "Carbohydrate binding module family 20 (21.1%) Glycoside hydrolase, family 77 (21.1%) Immunoglobulin-like fold (19.3%)" MNTAHATEEGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.40 (100%) pyruvate kinase (100%) "GO:0000287 (20.2%) GO:0004743 (20.2%) GO:0016301 (20.2%)" "magnesium ion binding (20.2%) pyruvate kinase activity (20.2%) kinase activity (20.2%)" "IPR015793 (11.8%) IPR001697 (11.2%) IPR015795 (11.2%)" "Pyruvate kinase, barrel (11.8%) Pyruvate kinase (11.2%) Pyruvate kinase, C-terminal (11.2%)" CAETLLAVMDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025632 (100%) Protein of unknown function DUF4290 (100%) NLDLLTAVQVALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0005975 (12.5%) GO:0006002 (12.5%) GO:0006047 (12.5%)" GO:0005829 (12.5%) "GO:0004360 (12.5%) GO:0097367 (12.5%)" "carbohydrate metabolic process (12.5%) fructose 6-phosphate metabolic process (12.5%) UDP-N-acetylglucosamine metabolic process (12.5%)" cytosol (12.5%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.5%) carbohydrate derivative binding (12.5%)" "IPR001347 (12.5%) IPR005855 (12.5%) IPR017932 (12.5%)" "SIS domain (12.5%) Glucosamine-fructose-6-phosphate aminotransferase, isomerising (12.5%) Glutamine amidotransferase type 2 domain (12.5%)" NYSDAELSQFEQQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025324 (100%) Protein of unknown function DUF4230 (100%) LKLDNEGVGSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) AFHDLGEDFCLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (20.8%) IPR018485 (20.8%) IPR050406 (20.8%)" "Carbohydrate kinase FGGY, N-terminal (20.8%) Carbohydrate kinase FGGY, C-terminal (20.8%) FGGY Carbohydrate Kinase (20.8%)" LNPNDLESFTVLK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (4.4%) GO:0009279 (91.2%) GO:0015344 (4.4%) siderophore transmembrane transport (4.4%) cell outer membrane (91.2%) siderophore uptake transmembrane transporter activity (4.4%) "IPR012910 (12.7%) IPR023996 (12.7%) IPR023997 (12.7%)" "TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" VFGTPSYYVQNVMANNLGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" DTLKNDLLNLSVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FHYYEGYDMK root 2.4.2.1 (100%) purine-nucleoside phosphorylase (100%) GO:0009116 (33.2%) GO:0005737 (33.2%) "GO:0004731 (33.2%) GO:0047975 (0.3%)" nucleoside metabolic process (33.2%) cytoplasm (33.2%) "purine-nucleoside phosphorylase activity (33.2%) guanosine phosphorylase activity (0.3%)" "IPR000845 (22.5%) IPR011268 (22.5%) IPR035994 (22.3%)" "Nucleoside phosphorylase domain (22.5%) Purine nucleoside phosphorylase (22.5%) Nucleoside phosphorylase superfamily (22.3%)" GLNLFSR root "2.3.3.13 (87.4%) 2.7.11.1 (3.8%) 1.1.1.49 (1.4%)" "2-isopropylmalate synthase (87.4%) non-specific serine/threonine protein kinase (3.8%) glucose-6-phosphate dehydrogenase (NADP(+)) (1.4%)" "GO:0009098 (13.6%) GO:0016042 (1.8%) GO:0006508 (0.8%)" "GO:0005737 (13.6%) GO:0016020 (2.4%) GO:0005886 (1.2%)" "GO:0003852 (13.6%) GO:0003985 (13.1%) GO:0000287 (13%)" "L-leucine biosynthetic process (13.6%) lipid catabolic process (1.8%) proteolysis (0.8%)" "cytoplasm (13.6%) membrane (2.4%) plasma membrane (1.2%)" "2-isopropylmalate synthase activity (13.6%) acetyl-CoA C-acetyltransferase activity (13.1%) magnesium ion binding (13%)" "IPR000891 (8.7%) IPR013785 (8.7%) IPR054692 (8.7%)" "Pyruvate carboxyltransferase (8.7%) Aldolase-type TIM barrel (8.7%) 2-isopropylmalate synthase-like, post-catalytic domain (8.7%)" FNELFNLDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (8.3%) "GO:0000155 (31%) GO:0003700 (29.8%) GO:0043565 (29.8%)" membrane (8.3%) "phosphorelay sensor kinase activity (31%) DNA-binding transcription factor activity (29.8%) sequence-specific DNA binding (29.8%)" "IPR015943 (11.5%) IPR011110 (11.1%) IPR001789 (10.7%)" "WD40/YVTN repeat-like-containing domain superfamily (11.5%) Two component regulator propeller (11.1%) Signal transduction response regulator, receiver domain (10.7%)" TPMQWTK root "3.2.1.1 (50%) 3.2.1.10 (20%) 3.2.1.93 (20%)" "alpha-amylase (50%) oligo-1,6-glucosidase (20%) alpha,alpha-phosphotrehalase (20%)" "GO:0009313 (44.2%) GO:0000025 (0.7%) GO:0005975 (0.7%)" GO:0005737 (0.7%) "GO:0004556 (45.7%) GO:0043169 (2.9%) GO:0004574 (0.7%)" "oligosaccharide catabolic process (44.2%) maltose catabolic process (0.7%) carbohydrate metabolic process (0.7%)" cytoplasm (0.7%) "alpha-amylase activity (45.7%) cation binding (2.9%) oligo-1,6-glucosidase activity (0.7%)" "IPR006047 (24.4%) IPR017853 (23.7%) IPR045857 (23.7%)" "Glycosyl hydrolase family 13, catalytic domain (24.4%) Glycoside hydrolase superfamily (23.7%) Oligo-1,6-glucosidase, domain 2 (23.7%)" NNDAWYEPSHFEYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.3%) IPR012944 (35.3%) IPR033985 (29.4%)" "Tetratricopeptide-like helical domain superfamily (35.3%) RagB/SusD domain (35.3%) SusD-like, N-terminal (29.4%)" TLVFSYLGYQTK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (7.7%) GO:0009279 (92.3%) iron ion transport (7.7%) cell outer membrane (92.3%) "IPR008969 (13.2%) IPR012910 (13.2%) IPR036942 (13.2%)" "Carboxypeptidase-like, regulatory domain superfamily (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.2%)" NPNSLPEHELTRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) FVCLDGPEFDGAQVDWDEMFKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (48.9%) GO:0051536 (48.9%) GO:0004355 (2.1%)" "oxidoreductase activity (48.9%) iron-sulfur cluster binding (48.9%) glutamate synthase (NADPH) activity (2.1%)" "IPR017927 (11.4%) IPR019480 (11.4%) IPR023753 (11.4%)" "FAD-binding domain, ferredoxin reductase-type (11.4%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.4%) FAD/NAD(P)-binding domain (11.4%)" NVELNVFDGPCPAGNVGVQVNNLDPVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.2%) IPR022615 (20.2%) IPR056147 (20.2%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.2%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.2%) NqrA, N-terminal barrel-sandwich hybrid domain (20.2%)" LTFELGHDLTSPSDDNLLHNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.7%) IPR008969 (48.3%)" "Family of unknown function DUF5686 (51.7%) Carboxypeptidase-like, regulatory domain superfamily (48.3%)" KFLYSDHDLFLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005524 (24.8%) GO:0016887 (24.8%) GO:0051082 (24.8%)" "ATP binding (24.8%) ATP hydrolysis activity (24.8%) unfolded protein binding (24.8%)" "IPR001404 (18%) IPR019805 (18%) IPR020575 (18%)" "Heat shock protein Hsp90 family (18%) Heat shock protein Hsp90, conserved site (18%) Heat shock protein Hsp90, N-terminal (18%)" EVLKNETLAVLGYGLQGPGQACNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.86 (92.6%) 1.1.1.- (7.4%)" "ketol-acid reductoisomerase (NADP(+)) (92.6%) With NAD(+) or NADP(+) as acceptor (7.4%)" "GO:0009097 (21.4%) GO:0009099 (21.4%)" "GO:0004455 (21.4%) GO:0046872 (20.5%) GO:0016853 (15.4%)" "isoleucine biosynthetic process (21.4%) L-valine biosynthetic process (21.4%)" "ketol-acid reductoisomerase activity (21.4%) metal ion binding (20.5%) isomerase activity (15.4%)" "IPR000506 (17%) IPR013023 (17%) IPR013116 (17%)" "Ketol-acid reductoisomerase, C-terminal (17%) Ketol-acid reductoisomerase (17%) Ketol-acid reductoisomerase, N-terminal (17%)" TNADTPHDAEVAR root "2.7.9.1 (99.6%) 2.7.-.- (0.4%)" "pyruvate, phosphate dikinase (99.6%) Transferring phosphorus-containing groups (0.4%)" "GO:0050242 (25.4%) GO:0016301 (25.3%) GO:0046872 (24.9%)" "pyruvate, phosphate dikinase activity (25.4%) kinase activity (25.3%) metal ion binding (24.9%)" "IPR000121 (10.1%) IPR010121 (10.1%) IPR015813 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate, phosphate dikinase (10.1%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.1%)" TLVLEQNFGFAEGYNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001173 (51.4%) IPR029044 (48.6%)" "Glycosyltransferase 2-like (51.4%) Nucleotide-diphospho-sugar transferases (48.6%)" VNLGAGSAEQGSQSGLEDLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" FLTASSADLLCYGYDGELYTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.3%) IPR011659 (14.3%) IPR012393 (14.3%)" "Tail specific protease (14.3%) WD40-like beta-propeller (14.3%) Tricorn protease (14.3%)" MKYNFDELLER Bacteria Bacteria 4.4.1.13 (100%) cysteine-S-conjugate beta-lyase (100%) "GO:0016829 (37.7%) GO:0030170 (37.7%) GO:0008483 (24.6%)" "lyase activity (37.7%) pyridoxal phosphate binding (37.7%) transaminase activity (24.6%)" "IPR004839 (17%) IPR051798 (17%) IPR027619 (16.7%)" "Aminotransferase, class I/classII, large domain (17%) Class-II Pyridoxal-Phosphate-Dependent Aminotransferase (17%) C-S lyase, PatB-like (16.7%)" KYNYSGYSALNTALDEALAALESAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" SAVDLSGTLKPWTEAGDNNEHLAQ Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (53.3%) IPR042278 (46.7%)" "Fimbrillin-like 1 (53.3%) Fimbrillin-like 1, N-terminal (46.7%)" ALENSDVCLLMLDATR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (31.3%) "GO:0005525 (31.3%) GO:0043022 (31.3%) GO:0016787 (6%)" ribosome biogenesis (31.3%) "GTP binding (31.3%) ribosome binding (31.3%) hydrolase activity (6%)" "IPR005225 (14.4%) IPR006073 (14.4%) IPR016484 (14.4%)" "Small GTP-binding domain (14.4%) GTP binding domain (14.4%) GTPase Der (14.4%)" VYVQAMNPFTLYKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.5%) IPR023996 (13.5%) IPR023997 (13.5%)" "TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.5%)" EYMPYTVELGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.- (100%) Transferring groups other than amino-acyl groups (100%) GO:0006629 (50%) GO:0016746 (50%) lipid metabolic process (50%) acyltransferase activity (50%) "IPR052351 (52.9%) IPR016181 (47.1%)" "L-ornithine N(alpha)-acyltransferase (52.9%) Acyl-CoA N-acyltransferase (47.1%)" YAGVAEDGSALYYNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR023996 (14.2%) IPR039426 (14.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent receptor-like (14.2%)" ANDECVPVTEKDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (33.3%) IPR020845 (33.3%) IPR042099 (33.3%)" "AMP-dependent synthetase/ligase domain (33.3%) AMP-binding, conserved site (33.3%) ANL, N-terminal domain (33.3%)" EGQPETCQLTAGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" YLPETLLSSNHSGTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" ANLNAALR root 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0019646 (5%) GO:0000271 (3.3%) GO:0006432 (3.3%)" "GO:0016020 (20%) GO:0005737 (5%) GO:0005634 (3.3%)" "GO:0016757 (6.7%) GO:0003955 (5%) GO:0005524 (5%)" "aerobic electron transport chain (5%) polysaccharide biosynthetic process (3.3%) phenylalanyl-tRNA aminoacylation (3.3%)" "membrane (20%) cytoplasm (5%) nucleus (3.3%)" "glycosyltransferase activity (6.7%) NAD(P)H dehydrogenase (quinone) activity (5%) ATP binding (5%)" "IPR041662 (15.1%) IPR011990 (14%) IPR024302 (8.7%)" "SusD-like 2 (15.1%) Tetratricopeptide-like helical domain superfamily (14%) SusD-like (8.7%)" DGTLHDLPWKK Pseudomonadati Bacteria Pseudomonadati GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) AFCKPFNEVGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.4.1.1 (66.7%) 2.1.3.1 (33.3%)" "pyruvate carboxylase (66.7%) methylmalonyl-CoA carboxytransferase (33.3%)" GO:0006094 (33.1%) GO:0005737 (33.1%) "GO:0004736 (33.1%) GO:0016740 (0.7%)" gluconeogenesis (33.1%) cytoplasm (33.1%) "pyruvate carboxylase activity (33.1%) transferase activity (0.7%)" "IPR000891 (21.4%) IPR003379 (21.4%) IPR055268 (21.4%)" "Pyruvate carboxyltransferase (21.4%) Carboxylase, conserved domain (21.4%) Pyruvate carboxylase-like (21.4%)" ALNPYSQNQAFMALAEQPEMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.3%) GO:0005829 (32.3%) "GO:0008926 (32.3%) GO:0009026 (3.1%)" mannitol catabolic process (32.3%) cytosol (32.3%) "mannitol-1-phosphate 5-dehydrogenase activity (32.3%) tagaturonate reductase activity (3.1%)" "IPR013131 (22.6%) IPR013118 (21.5%) IPR036291 (19.4%)" "Mannitol dehydrogenase, N-terminal (22.6%) Mannitol dehydrogenase, C-terminal (21.5%) NAD(P)-binding domain superfamily (19.4%)" GYTLQPYSPGAGTGLSSHELNQPGCYR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" LFVKPEDLELR Bacteria Bacteria GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.6%) IPR006512 (25.6%) IPR050144 (25.6%)" "Regulator of K+ conductance, C-terminal (25.6%) YidE/YbjL duplication (25.6%) AAE Transporter (25.6%)" QEYVAPKPEPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (33.7%) IPR050330 (33.7%) IPR036737 (32.7%)" "OmpA-like domain (33.7%) Bacterial Outer Membrane Structural/Functional (33.7%) OmpA-like domain superfamily (32.7%)" AGLPFHEGFLNLFDHSGNAFVSAYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.9 (100%) uracil phosphoribosyltransferase (100%) "GO:0005525 (44.4%) GO:0004845 (33.3%) GO:0016757 (22.2%)" "GTP binding (44.4%) uracil phosphoribosyltransferase activity (33.3%) glycosyltransferase activity (22.2%)" "IPR000836 (40%) IPR029057 (40%) IPR050137 (20%)" "Phosphoribosyltransferase domain (40%) Phosphoribosyltransferase-like (40%) PyrR bifunctional (20%)" LHKDGVEGLALGVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (25%) GO:0005886 (25%) "GO:0010181 (25%) GO:0016655 (25%)" sodium ion transport (25%) plasma membrane (25%) "FMN binding (25%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (25%)" "IPR007329 (50%) IPR010204 (50%)" "FMN-binding (50%) Na(+)-translocating NADH-quinone reductase subunit C (50%)" MLSYGGSNYNLSFLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.4%) GO:0009090 (17.4%) GO:0009088 (12.1%)" GO:0005829 (17.4%) "GO:0005524 (17.8%) GO:0004072 (17.4%) GO:0016301 (0.4%)" "lysine biosynthetic process via diaminopimelate (17.4%) homoserine biosynthetic process (17.4%) threonine biosynthetic process (12.1%)" cytosol (17.4%) "ATP binding (17.8%) aspartate kinase activity (17.4%) kinase activity (0.4%)" "IPR045865 (14.4%) IPR054352 (14.4%) IPR001048 (14.1%)" "ACT-like domain (14.4%) Aspartokinase, ACT domain (14.4%) Aspartate/glutamate/uridylate kinase (14.1%)" SGLESVLSK root "GO:0006974 (31.8%) GO:0050821 (9.1%)" "GO:0016020 (27.3%) GO:0005737 (9.1%) GO:0005634 (4.5%)" "GO:0000774 (9.1%) GO:0051087 (9.1%)" "DNA damage response (31.8%) protein stabilization (9.1%)" "membrane (27.3%) cytoplasm (9.1%) nucleus (4.5%)" "adenyl-nucleotide exchange factor activity (9.1%) protein-folding chaperone binding (9.1%)" "IPR007497 (21.9%) IPR016907 (21.9%) IPR052022 (21.9%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (21.9%) Uncharacterised conserved protein UCP029033, periplasmic protein (21.9%) 26 kDa periplasmic antigen-related (21.9%)" YAELDENTYANSDYLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (39.6%) IPR011990 (35.8%) IPR024302 (24.5%)" "SusD-like 2 (39.6%) Tetratricopeptide-like helical domain superfamily (35.8%) SusD-like (24.5%)" LVEGGYNVVAVVTQPDKPVGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.2.9 (100%) methionyl-tRNA formyltransferase (100%) GO:0005829 (50%) GO:0004479 (50%) cytosol (50%) methionyl-tRNA formyltransferase activity (50%) "IPR002376 (13.5%) IPR041711 (13.5%) IPR005793 (13.3%)" "Formyl transferase, N-terminal (13.5%) Methionyl-tRNA formyltransferase, N-terminal domain (13.5%) Formyl transferase, C-terminal (13.3%)" FHLLNMNLTDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.7%) IPR025896 (16.7%) IPR026906 (16.7%)" "Peptidase C10, streptopain (16.7%) Spi protease inhibitor (16.7%) BspA-type LRR region (16.7%)" HQGNGELQSPTGAQCAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GRDLVLNDQSNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (44.7%) "GO:0052689 (44.7%) GO:0004557 (10.5%)" cell outer membrane (44.7%) "carboxylic ester hydrolase activity (44.7%) alpha-galactosidase activity (10.5%)" "IPR032812 (25.8%) IPR044060 (25.8%) IPR011050 (24.2%)" "SbsA, Ig-like domain (25.8%) Bacterial repeat domain (25.8%) Pectin lyase fold/virulence factor (24.2%)" KYSLLFSK root 2.7.8.15 (100%) UDP-N-acetylglucosamine--dolichyl-phosphatN-acetylglucosaminephosphotransferase (100%) "GO:0050821 (19.7%) GO:0002376 (1.5%) GO:0006488 (1.5%)" "GO:0005829 (19.7%) GO:0016020 (6.1%) GO:0005737 (1.5%)" "GO:0051082 (19.7%) GO:0019888 (3%) GO:0019903 (3%)" "protein stabilization (19.7%) immune system process (1.5%) dolichol-linked oligosaccharide biosynthetic process (1.5%)" "cytosol (19.7%) membrane (6.1%) cytoplasm (1.5%)" "unfolded protein binding (19.7%) protein phosphatase regulator activity (3%) protein phosphatase binding (3%)" "IPR005632 (20%) IPR024930 (20%) IPR036770 (10.8%)" "Chaperone protein Skp (20%) Skp domain superfamily (20%) Ankyrin repeat-containing domain superfamily (10.8%)" YQGNNYSPMGHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.5%) IPR024742 (20.5%) IPR032790 (20.5%)" "Glycogen debranching enzyme (20.5%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.5%) Glycogen debranching enzyme, C-terminal (20.5%)" RFGDSFDEAQFR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (13%) GO:0015966 (12.2%)" "GO:0005737 (13%) GO:0070062 (12.2%) GO:1990742 (12.2%)" "GO:0004820 (13%) GO:0004081 (12.2%) GO:0005524 (12.2%)" "glycyl-tRNA aminoacylation (13%) diadenosine tetraphosphate biosynthetic process (12.2%)" "cytoplasm (13%) extracellular exosome (12.2%) microvesicle (12.2%)" "glycine-tRNA ligase activity (13%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.2%) ATP binding (12.2%)" "IPR027031 (11.8%) IPR002314 (11.1%) IPR002315 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.8%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Glycyl-tRNA synthetase (11.1%)" TTDVCEGNALFLLGRPESHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (30.9%) GO:0005576 (30.9%) "GO:0004650 (30.9%) GO:0004557 (7.4%)" carbohydrate metabolic process (30.9%) extracellular region (30.9%) "polygalacturonase activity (30.9%) alpha-galactosidase activity (7.4%)" "IPR000743 (28%) IPR011050 (26.7%) IPR012334 (26.7%)" "Glycoside hydrolase, family 28 (28%) Pectin lyase fold/virulence factor (26.7%) Pectin lyase fold (26.7%)" MPQSTLKEWEELGVPEDWAYVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.9%) GO:0005829 (16.9%) "GO:0000049 (16.9%) GO:0004824 (16.9%) GO:0005524 (16.9%)" lysyl-tRNA aminoacylation (16.9%) cytosol (16.9%) "tRNA binding (16.9%) lysine-tRNA ligase activity (16.9%) ATP binding (16.9%)" "IPR004364 (13.3%) IPR006195 (13.3%) IPR002313 (12.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (13.3%) Aminoacyl-tRNA synthetase, class II (13.3%) Lysine-tRNA ligase, class II (12.4%)" GYLCDVTDEEQVK Bacteria Bacteria 1.1.1.69 (100%) gluconate 5-dehydrogenase (100%) GO:0008206 (5.9%) "GO:0008874 (52.9%) GO:0016491 (35.3%) GO:0016616 (5.9%)" bile acid metabolic process (5.9%) "gluconate 5-dehydrogenase activity (52.9%) oxidoreductase activity (35.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (5.9%)" "IPR002347 (31.5%) IPR036291 (31.5%) IPR020904 (29.6%)" "Short-chain dehydrogenase/reductase SDR (31.5%) NAD(P)-binding domain superfamily (31.5%) Short-chain dehydrogenase/reductase, conserved site (29.6%)" GMTGGGYTFLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025396 (100%) Protein of unknown function DUF4302 (100%) MTGAANNPGWYYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) ALSLFVQPPSVEELRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.7.4.8 (94.7%) 2.7.-.- (5.3%)" "guanylate kinase (94.7%) Transferring phosphorus-containing groups (5.3%)" GO:0005829 (34%) "GO:0004385 (34%) GO:0005524 (32.1%)" cytosol (34%) "GMP kinase activity (34%) ATP binding (32.1%)" "IPR008144 (20.7%) IPR008145 (20.7%) IPR017665 (19.5%)" "Guanylate kinase-like domain (20.7%) Guanylate kinase/L-type calcium channel beta subunit (20.7%) Guanylate kinase (19.5%)" GKFELLGVDCNDTEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (23.7%) GO:0030313 (22.2%) "GO:0016209 (26.7%) GO:0016491 (26.7%) GO:0004601 (0.7%)" cytochrome complex assembly (23.7%) cell envelope (22.2%) "antioxidant activity (26.7%) oxidoreductase activity (26.7%) peroxidase activity (0.7%)" "IPR000866 (20.9%) IPR013766 (20.9%) IPR050553 (20.9%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.9%) Thioredoxin domain (20.9%) Thioredoxin family ResA/DsbE subfamily (20.9%)" LFYPTPQTELNSNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" ASAFYHFNWGTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" KQTLAFLDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EAGADYVGLDEYVEKLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (17%) GO:0006417 (16%)" GO:0015934 (17%) "GO:0003735 (17%) GO:0019843 (17%) GO:0000049 (16%)" "translation (17%) regulation of translation (16%)" large ribosomal subunit (17%) "structural constituent of ribosome (17%) rRNA binding (17%) tRNA binding (16%)" "IPR005878 (17.2%) IPR023673 (17.2%) IPR028364 (17.2%)" "Large ribosomal subunit protein uL1, bacteria (17.2%) Large ribosomal subunit protein uL1, conserved site (17.2%) Ribosomal protein uL1/ribosomal biogenesis protein (17.2%)" TKPGDLFSK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0071709 (49.2%) "GO:0009279 (47.2%) GO:0019867 (3.6%)" membrane assembly (49.2%) "cell outer membrane (47.2%) outer membrane (3.6%)" "IPR010827 (22.8%) IPR034746 (22.5%) IPR023707 (22%)" "POTRA domain, BamA/TamA-like (22.8%) POTRA domain (22.5%) Outer membrane protein assembly factor BamA (22%)" VKEELPQVYNLSLLWQYYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001173 (51.9%) IPR029044 (48.1%)" "Glycosyltransferase 2-like (51.9%) Nucleotide-diphospho-sugar transferases (48.1%)" NFEVNKELER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (33.3%) GO:0005829 (33.3%) GO:0004056 (33.3%) L-arginine biosynthetic process via ornithine (33.3%) cytosol (33.3%) argininosuccinate lyase activity (33.3%) "IPR009049 (17%) IPR022761 (17%) IPR000362 (16.5%)" "Argininosuccinate lyase (17%) Fumarate lyase, N-terminal (17%) Fumarate lyase family (16.5%)" EYHVAHANLLGLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015679 (20.6%) GO:0060003 (20.6%)" "GO:0030313 (20.6%) GO:0016020 (19%)" GO:0022857 (19%) "plasma membrane copper ion transport (20.6%) copper ion export (20.6%)" "cell envelope (20.6%) membrane (19%)" transmembrane transporter activity (19%) "IPR032317 (33.3%) IPR051909 (33.3%) IPR006143 (30.8%)" "Unknown (33.3%) Membrane Fusion Protein Cation Efflux System (33.3%) RND efflux pump, membrane fusion protein (30.8%)" AVEEHYLAASR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) GO:0042274 (16.7%) GO:0005737 (16.7%) "GO:0003924 (16.7%) GO:0005525 (16.7%) GO:0019843 (16.7%)" ribosomal small subunit biogenesis (16.7%) cytoplasm (16.7%) "GTPase activity (16.7%) GTP binding (16.7%) rRNA binding (16.7%)" "IPR004881 (17%) IPR010914 (17%) IPR030378 (17%)" "Ribosome biogenesis GTPase RsgA (17%) RsgA GTPase domain (17%) Circularly permuted (CP)-type guanine nucleotide-binding (G) domain (17%)" NLGVPLGHSVLALQSTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (20.4%) GO:0044208 (20.4%) GO:0006188 (16.3%)" "GO:0004018 (36.7%) GO:0070626 (6.1%)" "'de novo' IMP biosynthetic process (20.4%) 'de novo' AMP biosynthetic process (20.4%) IMP biosynthetic process (16.3%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (36.7%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (6.1%)" "IPR000362 (12.5%) IPR004769 (12.5%) IPR008948 (12.5%)" "Fumarate lyase family (12.5%) Adenylosuccinate lyase (12.5%) L-Aspartase-like (12.5%)" GLNVTLPYK root "1.1.1.25 (81.1%) 2.7.1.71 (18.5%) 4.2.1.10 (0.2%)" "shikimate dehydrogenase (NADP(+)) (81.1%) shikimate kinase (18.5%) 3-dehydroquinate dehydratase (0.2%)" "GO:0009423 (15.8%) GO:0019632 (15.8%) GO:0009073 (15.4%)" "GO:0005829 (14.7%) GO:0005737 (0.4%) GO:0016020 (0.1%)" "GO:0004764 (15.8%) GO:0050661 (14.8%) GO:0004765 (1.3%)" "chorismate biosynthetic process (15.8%) shikimate metabolic process (15.8%) aromatic amino acid family biosynthetic process (15.4%)" "cytosol (14.7%) cytoplasm (0.4%) membrane (0.1%)" "shikimate 3-dehydrogenase (NADP+) activity (15.8%) NADP binding (14.8%) shikimate kinase activity (1.3%)" "IPR013708 (22.1%) IPR022893 (22%) IPR046346 (22%)" "Shikimate dehydrogenase substrate binding, N-terminal (22.1%) Shikimate dehydrogenase family (22%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (22%)" VGLYYAETGASMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.92 (100%) 5-dehydro-2-deoxygluconokinase (100%) "GO:0016301 (97.9%) GO:0047590 (2.1%)" "kinase activity (97.9%) 5-dehydro-2-deoxygluconokinase activity (2.1%)" "IPR011611 (33.6%) IPR052700 (33.6%) IPR029056 (32.9%)" "Carbohydrate kinase PfkB (33.6%) Carbohydrate kinase PfkB-like (33.6%) Ribokinase-like (32.9%)" LQHYTETVGAGDFQLSQFQDWVLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" LVSPYDNQGLSSLMYVSEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR031704 (12.9%) IPR031705 (12.9%)" "Glycoside hydrolase family 36 (12.9%) Glycosyl hydrolase family 36, N-terminal (12.9%) Glycosyl hydrolase family 36, C-terminal (12.9%)" LLGELYTK root "2.7.11.23 (50.8%) 2.7.11.22 (42.9%) 2.7.11.1 (3.2%)" "[RNA-polymerase]-subunit kinase (50.8%) cyclin-dependent kinase (42.9%) non-specific serine/threonine protein kinase (3.2%)" "GO:0032968 (5.1%) GO:0016192 (2.6%) GO:0015833 (0.6%)" "GO:0009279 (19.6%) GO:1990351 (19.6%) GO:0008024 (5.1%)" "GO:0005524 (6.6%) GO:0008353 (5.1%) GO:0030332 (5.1%)" "positive regulation of transcription elongation by RNA polymerase II (5.1%) vesicle-mediated transport (2.6%) peptide transport (0.6%)" "cell outer membrane (19.6%) transporter complex (19.6%) cyclin/CDK positive transcription elongation factor complex (5.1%)" "ATP binding (6.6%) RNA polymerase II CTD heptapeptide repeat kinase activity (5.1%) cyclin binding (5.1%)" "IPR045659 (17.2%) IPR050218 (17.2%) IPR000719 (4.8%)" "LPS-assembly protein LptD, central domain (17.2%) Lipopolysaccharide Assembly Protein LptD (17.2%) Protein kinase domain (4.8%)" GPDWSGLYCGGSALLAHER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (24.9%) GO:0005829 (24.9%) "GO:0004066 (24.9%) GO:0005524 (24.9%) GO:0016874 (0.4%)" obsolete asparagine biosynthetic process (24.9%) cytosol (24.9%) "asparagine synthase (glutamine-hydrolyzing) activity (24.9%) ATP binding (24.9%) ligase activity (0.4%)" "IPR001962 (14.3%) IPR006426 (14.3%) IPR017932 (14.3%)" "Asparagine synthase (14.3%) Asparagine synthase, glutamine-hydrolyzing (14.3%) Glutamine amidotransferase type 2 domain (14.3%)" YFGCPLVLCNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.2%) GO:0006164 (11.2%) GO:0009156 (10.3%)" "GO:0002189 (11.2%) GO:0005737 (11.2%)" "GO:0000287 (11.2%) GO:0004749 (11.2%) GO:0005524 (11.2%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.2%) purine nucleotide biosynthetic process (11.2%) ribonucleoside monophosphate biosynthetic process (10.3%)" "ribose phosphate diphosphokinase complex (11.2%) cytoplasm (11.2%)" "magnesium ion binding (11.2%) ribose phosphate diphosphokinase activity (11.2%) ATP binding (11.2%)" "IPR000836 (17.6%) IPR005946 (17.6%) IPR029057 (17.6%)" "Phosphoribosyltransferase domain (17.6%) Ribose-phosphate pyrophosphokinase (17.6%) Phosphoribosyltransferase-like (17.6%)" NLTQAFYDNQMSLEVDLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LNLYYGAR Pseudomonadati Bacteria Pseudomonadati GO:0044718 (3.4%) GO:0009279 (87.9%) GO:0015344 (8.6%) siderophore transmembrane transport (3.4%) cell outer membrane (87.9%) siderophore uptake transmembrane transporter activity (8.6%) "IPR036942 (87.9%) IPR039426 (8.6%) IPR057601 (3.4%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (87.9%) TonB-dependent receptor-like (8.6%) TonB-dependent transporter Oar-like, beta-barrel domain (3.4%)" VSLSEEPAAELPVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.5%) GO:0019288 (18.5%)" "GO:0046429 (18.5%) GO:0051539 (18.5%) GO:0005506 (17.1%)" "terpenoid biosynthetic process (18.5%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.5%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.5%) 4 iron, 4 sulfur cluster binding (18.5%) iron ion binding (17.1%)" "IPR004588 (26.4%) IPR011005 (24.9%) IPR017178 (24.4%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26.4%) Dihydropteroate synthase-like superfamily (24.9%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.4%)" FLAPFLSR root "2.7.11.1 (78.6%) 3.1.-.- (7.1%) 5.6.2.4 (7.1%)" "non-specific serine/threonine protein kinase (78.6%) Acting on ester bonds (7.1%) DNA 3'-5' helicase (7.1%)" "GO:0007160 (9.3%) GO:0006397 (7.8%) GO:0006884 (3%)" "GO:0009279 (11.3%) GO:0016020 (10.7%) GO:0000445 (7.8%)" "GO:0020037 (4.5%) GO:0016491 (4.2%) GO:0046872 (4.2%)" "cell-matrix adhesion (9.3%) mRNA processing (7.8%) cell volume homeostasis (3%)" "cell outer membrane (11.3%) membrane (10.7%) THO complex part of transcription export complex (7.8%)" "heme binding (4.5%) oxidoreductase activity (4.2%) metal ion binding (4.2%)" "IPR000184 (6%) IPR039910 (6%) IPR003886 (4.9%)" "Bacterial surface antigen (D15) (6%) Surface antigen D15-like (6%) NIDO domain (4.9%)" KVVVVGGGNTAMDSCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (49%) GO:0051536 (49%) GO:0004355 (2%)" "oxidoreductase activity (49%) iron-sulfur cluster binding (49%) glutamate synthase (NADPH) activity (2%)" "IPR023753 (11%) IPR006004 (10.8%) IPR017927 (10.8%)" "FAD/NAD(P)-binding domain (11%) Sulfide dehydrogenase subunit alpha-like (10.8%) FAD-binding domain, ferredoxin reductase-type (10.8%)" AFESLLSANVECK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004674 (100%) protein serine/threonine kinase activity (100%) "IPR024361 (22.7%) IPR013783 (21.3%) IPR032675 (20.7%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (22.7%) Immunoglobulin-like fold (21.3%) Leucine-rich repeat domain superfamily (20.7%)" GMLNLEGLPVYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.7.9.2 (66.7%) 6.1.1.20 (33.3%)" "pyruvate, water dikinase (66.7%) phenylalanine--tRNA ligase (33.3%)" "GO:0003723 (49.2%) GO:0004826 (49.2%) GO:0008986 (1.7%)" "RNA binding (49.2%) phenylalanine-tRNA ligase activity (49.2%) pyruvate, water dikinase activity (1.7%)" "IPR005146 (50.9%) IPR020825 (49.1%)" "B3/B4 tRNA-binding domain (50.9%) Phenylalanyl-tRNA synthetase-like, B3/B4 (49.1%)" AADLTAHQVLVNLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0008270 (50%) GO:0016491 (50%)" "zinc ion binding (50%) oxidoreductase activity (50%)" "IPR002328 (16.7%) IPR011032 (16.7%) IPR013149 (16.7%)" "Alcohol dehydrogenase, zinc-type, conserved site (16.7%) GroES-like superfamily (16.7%) Alcohol dehydrogenase-like, C-terminal (16.7%)" KELEALGVTCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (31.1%) GO:0030497 (2.2%)" "GO:0004316 (33.3%) GO:0051287 (33.3%)" "fatty acid biosynthetic process (31.1%) fatty acid elongation (2.2%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (33.3%) NAD binding (33.3%)" "IPR002347 (18.1%) IPR036291 (17%) IPR057326 (17%)" "Short-chain dehydrogenase/reductase SDR (18.1%) NAD(P)-binding domain superfamily (17%) Ketoreductase domain (17%)" ADLLNEVALATGMPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030261 (22.2%) GO:0005829 (22.2%) "GO:0003677 (27.8%) GO:0030527 (27.8%)" chromosome condensation (22.2%) cytosol (22.2%) "DNA binding (27.8%) structural constituent of chromatin (27.8%)" "IPR000119 (55.6%) IPR010992 (44.4%)" "Histone-like DNA-binding protein (55.6%) Integration host factor (IHF)-like DNA-binding domain superfamily (44.4%)" ENLLGVSHEVLEEQTAVCEEVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008136 (55%) IPR036653 (45%)" "CinA, C-terminal (55%) CinA-like, C-terminal (45%)" AQMVDMLSRDEFVNVLNQFGTDNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.1%) IPR012910 (12.1%) IPR023996 (12.1%)" "TonB-dependent receptor-like, beta-barrel (12.1%) TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein, SusC/RagA (12.1%)" LGGLQFAGGLFTNLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.6%) GO:0051301 (12.6%) GO:0009252 (11.9%)" GO:0005737 (12.6%) "GO:0005524 (13.2%) GO:0000287 (11.9%) GO:0008765 (11.9%)" "regulation of cell shape (12.6%) cell division (12.6%) peptidoglycan biosynthetic process (11.9%)" cytoplasm (12.6%) "ATP binding (13.2%) magnesium ion binding (11.9%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (11.9%)" "IPR013221 (15%) IPR036565 (15%) IPR004101 (14.3%)" "Mur ligase, central (15%) Mur-like, catalytic domain superfamily (15%) Mur ligase, C-terminal (14.3%)" NYLEDLLNGLAEDYEDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LRGEFALEK root 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (19.5%) GO:0042840 (19.5%) GO:0045490 (19.5%)" GO:0016020 (1.1%) "GO:0008270 (19.5%) GO:0008697 (19.5%)" "D-galacturonate catabolic process (19.5%) D-glucuronate catabolic process (19.5%) pectin catabolic process (19.5%)" membrane (1.1%) "zinc ion binding (19.5%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (19.5%)" "IPR007045 (20.2%) IPR021120 (20.2%) IPR011051 (19%)" "5-keto 4-deoxyuronate isomerase (20.2%) KduI/IolB isomerase (20.2%) RmlC-like cupin domain superfamily (19%)" VMQELFNDPAWVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.5%) GO:0016787 (48.5%) membrane (51.5%) hydrolase activity (48.5%) "IPR000560 (51.5%) IPR029033 (48.5%)" "Histidine phosphatase superfamily, clade-2 (51.5%) Histidine phosphatase superfamily (48.5%)" NAELYPDACKQDAEAQLSWLDETLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.2 (100%) acid phosphatase (100%) "GO:0003993 (50%) GO:0046872 (50%)" "acid phosphatase activity (50%) metal ion binding (50%)" "IPR004843 (25%) IPR024927 (25%) IPR029052 (25%)" "Calcineurin-like, phosphoesterase domain (25%) Purple acid phosphatase (25%) Metallo-dependent phosphatase-like (25%)" GGGLSQSALQQMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.8%) IPR004134 (33.8%) IPR038765 (32.5%)" "Cysteine peptidase, cysteine active site (33.8%) Peptidase C1B, bleomycin hydrolase (33.8%) Papain-like cysteine peptidase superfamily (32.5%)" DVYLYQELSQNPGW Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.3%) IPR011990 (32.4%) IPR033985 (32.4%)" "RagB/SusD domain (35.3%) Tetratricopeptide-like helical domain superfamily (32.4%) SusD-like, N-terminal (32.4%)" CLLASSYFNLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR033985 (34.4%) IPR012944 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) SusD-like, N-terminal (34.4%) RagB/SusD domain (31.3%)" VAAAECAGTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.3%) IPR008753 (20.3%) IPR018497 (20.3%)" "Peptidase M13 (20.3%) Peptidase M13, N-terminal domain (20.3%) Peptidase M13, C-terminal domain (20.3%)" EATGGTPDTPSKPDTPATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LLMNMPVLNKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.7%) IPR020845 (25.7%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.7%) ANL, N-terminal domain (24.3%)" EWEELGVPEDWAYVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.8%) GO:0005829 (16.8%) "GO:0000049 (16.8%) GO:0004824 (16.8%) GO:0005524 (16.8%)" lysyl-tRNA aminoacylation (16.8%) cytosol (16.8%) "tRNA binding (16.8%) lysine-tRNA ligase activity (16.8%) ATP binding (16.8%)" "IPR004364 (13.2%) IPR006195 (13.2%) IPR002313 (12.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (13.2%) Aminoacyl-tRNA synthetase, class II (13.2%) Lysine-tRNA ligase, class II (12.4%)" KSGGFTCSHLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "1.2.7.1 (75.5%) 1.2.7.- (19.8%) 1.2.1.51 (4.7%)" "pyruvate synthase (75.5%) With an iron-sulfur protein as acceptor (19.8%) pyruvate dehydrogenase (NADP(+)) (4.7%)" "GO:0006979 (14.7%) GO:0022900 (14.7%) GO:0044281 (11.9%)" "GO:0005506 (14.7%) GO:0051539 (14.7%) GO:0030976 (14.4%)" "response to oxidative stress (14.7%) electron transport chain (14.7%) small molecule metabolic process (11.9%)" "iron ion binding (14.7%) 4 iron, 4 sulfur cluster binding (14.7%) thiamine pyrophosphate binding (14.4%)" "IPR019752 (7.8%) IPR050722 (7.8%) IPR011895 (7.8%)" "Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (7.8%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" SWGATELSVSPDAK Pseudomonadati Bacteria Pseudomonadati 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR011659 (14.5%) IPR005151 (14.1%) IPR012393 (14.1%)" "WD40-like beta-propeller (14.5%) Tail specific protease (14.1%) Tricorn protease (14.1%)" LKPLYNDELLDEYFDVLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002716 (38.1%) IPR002850 (33.3%) IPR029060 (28.6%)" "PIN domain (38.1%) MJ1680-like (33.3%) PIN-like domain superfamily (28.6%)" GYYYNLNLFGGVSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" VMLAESDEKPER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25.9%) IPR046335 (25.9%) IPR010982 (24.1%)" "LacI-type HTH domain (25.9%) Transcriptional regulator LacI/GalR-like, sensor domain (25.9%) Lambda repressor-like, DNA-binding domain superfamily (24.1%)" NLTAHDMDQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.5%) IPR002942 (11.5%) IPR006145 (11.5%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.5%) RNA-binding S4 domain (11.5%) Pseudouridine synthase, RsuA/RluA-like (11.5%)" RNLYMPNSLVTLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026906 (33.3%) IPR032675 (33.3%) IPR053139 (33.3%)" "BspA-type LRR region (33.3%) Leucine-rich repeat domain superfamily (33.3%) Putative surface bspA-like protein (33.3%)" VEPYVNCQMVAGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.20 (100%) cellobiose phosphorylase (100%) GO:0005975 (33.1%) "GO:0030246 (32.5%) GO:0016757 (31.9%) GO:0016740 (1.2%)" carbohydrate metabolic process (33.1%) "carbohydrate binding (32.5%) glycosyltransferase activity (31.9%) transferase activity (1.2%)" "IPR033432 (12.8%) IPR052047 (12.8%) IPR010383 (12.6%)" "Glycosyl hydrolase 94, catalytic domain (12.8%) Glycosyl Hydrolase 94 Enzymes (12.8%) Glycosyl hydrolase 94, supersandwich domain (12.6%)" TQLGEFAPEFAHLNDDLLFGEVWSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0051920 (100%) peroxiredoxin activity (100%) "IPR047263 (21.2%) IPR003779 (20.3%) IPR011051 (19.5%)" "Hydroxynitrile lyase-like, cupin domain (21.2%) Carboxymuconolactone decarboxylase-like (20.3%) RmlC-like cupin domain superfamily (19.5%)" LSNLYSMQPVVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR053140 (34.1%) IPR013830 (32.9%) IPR036514 (32.9%)" "GDSL lipase Rv0518-like (34.1%) SGNH hydrolase-type esterase domain (32.9%) SGNH hydrolase superfamily (32.9%)" FLNENNVK root "6.3.5.5 (49.2%) 6.3.4.16 (47.5%) 2.1.1.228 (1.7%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (49.2%) carbamoyl-phosphate synthase (ammonia) (47.5%) tRNA (guanine(37)-N(1))-methyltransferase (1.7%)" "GO:0006221 (12.6%) GO:0006526 (12.6%) GO:0006541 (12.6%)" "GO:0005737 (13%) GO:0005886 (1.3%) GO:0005634 (0.9%)" "GO:0004088 (12.6%) GO:0005524 (12.6%) GO:0046872 (12.6%)" "pyrimidine nucleotide biosynthetic process (12.6%) L-arginine biosynthetic process (12.6%) glutamine metabolic process (12.6%)" "cytoplasm (13%) plasma membrane (1.3%) nucleus (0.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (12.6%) ATP binding (12.6%) metal ion binding (12.6%)" "IPR005479 (9.4%) IPR005480 (9.4%) IPR006275 (9.4%)" "Carbamoyl phosphate synthase, ATP-binding domain (9.4%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (9.4%) Carbamoyl-phosphate synthase, large subunit (9.4%)" ELHLNGPFNLQFMAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.1%) GO:0006526 (13.6%) GO:0006221 (12.7%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) L-arginine biosynthetic process (13.6%) pyrimidine nucleotide biosynthetic process (12.7%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.8%) IPR011761 (10.8%) IPR005480 (10%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.8%) ATP-grasp fold (10.8%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%)" MSEAQWDAVLNVNLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (31.7%) GO:0030497 (1.6%)" "GO:0004316 (31.7%) GO:0051287 (31.7%) GO:0016616 (1.6%)" "fatty acid biosynthetic process (31.7%) fatty acid elongation (1.6%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (31.7%) NAD binding (31.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (1.6%)" "IPR002347 (17.7%) IPR020904 (16.9%) IPR036291 (16.9%)" "Short-chain dehydrogenase/reductase SDR (17.7%) Short-chain dehydrogenase/reductase, conserved site (16.9%) NAD(P)-binding domain superfamily (16.9%)" VEGLDGNYYGLLYLPAGGEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" VLVPAESESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (18.7%) IPR002890 (18.7%) IPR008930 (18.7%)" "Alpha-2-macroglobulin (18.7%) Macroglobulin domain (18.7%) Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (18.7%)" GVVLYMQQEGR Bacteria Bacteria "3.5.4.25 (50.5%) 4.1.99.12 (49.5%)" "GTP cyclohydrolase II (50.5%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (49.5%)" GO:0009231 (12.6%) GO:0005829 (12.6%) "GO:0003935 (12.6%) GO:0005525 (12.6%) GO:0008686 (12.6%)" riboflavin biosynthetic process (12.6%) cytosol (12.6%) "GTP cyclohydrolase II activity (12.6%) GTP binding (12.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase activity (12.6%)" "IPR000926 (17%) IPR032677 (17%) IPR000422 (16.6%)" "GTP cyclohydrolase II, RibA (17%) GTP cyclohydrolase II (17%) 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.6%)" RTPYLNCYGAYVLNPDTQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.8%) GO:0005737 (32.3%) GO:0008734 (33.8%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.8%) cytoplasm (32.3%) L-aspartate oxidase activity (33.8%) "IPR003953 (17.3%) IPR005288 (17.3%) IPR015939 (16.5%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17.3%) L-aspartate oxidase (17.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.5%)" SNGVLEVLSEGYGFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.5%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.5%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.8%) IPR003593 (10.8%) IPR004665 (10.8%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.8%) AAA+ ATPase domain (10.8%) Transcription termination factor Rho (10.8%)" LEAFEYNGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (54.2%) IPR035994 (45.8%)" "Nucleoside phosphorylase domain (54.2%) Nucleoside phosphorylase superfamily (45.8%)" GANGVLLVTTKR Pseudomonadati Bacteria Pseudomonadati "GO:0044718 (4.5%) GO:0006826 (4.3%) GO:0000272 (0.3%)" GO:0009279 (85.9%) "GO:0015344 (4.6%) GO:0004553 (0.3%) GO:0004180 (0.1%)" "siderophore transmembrane transport (4.5%) iron ion transport (4.3%) polysaccharide catabolic process (0.3%)" cell outer membrane (85.9%) "siderophore uptake transmembrane transporter activity (4.6%) hydrolase activity, hydrolyzing O-glycosyl compounds (0.3%) carboxypeptidase activity (0.1%)" "IPR023997 (13.7%) IPR012910 (13.6%) IPR023996 (13.6%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (13.7%) TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%)" TLGMLEGFYGVTDDVVEVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0010181 (26.4%) GO:0009055 (24.5%) GO:0016491 (24.5%)" "FMN binding (26.4%) electron transfer activity (24.5%) oxidoreductase activity (24.5%)" "IPR045761 (17.9%) IPR001279 (17.3%) IPR008254 (16.8%)" "ODP domain (17.9%) Metallo-beta-lactamase (17.3%) Flavodoxin/nitric oxide synthase (16.8%)" GVFDAACRGEELEFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.2.3 (100%) dihydroorotase (100%) GO:0006145 (24.7%) GO:0005737 (24.7%) "GO:0004038 (24.7%) GO:0046872 (23.4%) GO:0004151 (2.6%)" purine nucleobase catabolic process (24.7%) cytoplasm (24.7%) "allantoinase activity (24.7%) metal ion binding (23.4%) dihydroorotase activity (2.6%)" "IPR002195 (20.4%) IPR006680 (20.4%) IPR050138 (20.4%)" "Dihydroorotase, conserved site (20.4%) Amidohydrolase-related (20.4%) Dihydroorotase/Allantoinase Hydrolase (20.4%)" ETLNTQAWLLHMMNPSEGWANMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (38.6%) IPR011990 (34.1%) IPR024302 (27.3%)" "SusD-like 2 (38.6%) Tetratricopeptide-like helical domain superfamily (34.1%) SusD-like (27.3%)" GDAHAQLGLYGAASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR050833 (50.7%) IPR002797 (49.3%)" "Polysaccharide Biosynthesis and Transport (50.7%) Polysaccharide biosynthesis protein (49.3%)" LMLTAGPTYEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.3%) GO:0015941 (14.2%)" GO:0071513 (14.2%) "GO:0004632 (14.2%) GO:0004633 (14.2%) GO:0010181 (14.2%)" "coenzyme A biosynthetic process (14.3%) pantothenate catabolic process (14.2%)" phosphopantothenoylcysteine decarboxylase complex (14.2%) "phosphopantothenate--cysteine ligase activity (14.2%) phosphopantothenoylcysteine decarboxylase activity (14.2%) FMN binding (14.2%)" "IPR007085 (20.4%) IPR003382 (20.2%) IPR005252 (20.2%)" "DNA/pantothenate metabolism flavoprotein, C-terminal (20.4%) Flavoprotein (20.2%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.2%)" TVLGTDPYMKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.1.21 (87.5%) 2.1.2.- (12.5%)" "phosphoribosylglycinamide formyltransferase 2 (87.5%) Hydroxymethyl-, formyl- and related transferases (12.5%)" "GO:0006189 (16.3%) GO:0006164 (0.5%)" GO:0005829 (16.7%) "GO:0005524 (16.7%) GO:0000287 (16.3%) GO:0004644 (16.3%)" "'de novo' IMP biosynthetic process (16.3%) purine nucleotide biosynthetic process (0.5%)" cytosol (16.7%) "ATP binding (16.7%) magnesium ion binding (16.3%) phosphoribosylglycinamide formyltransferase activity (16.3%)" "IPR003135 (12.8%) IPR011761 (12.8%) IPR048740 (12.8%)" "ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type (12.8%) ATP-grasp fold (12.8%) PurT, C-terminal (12.8%)" EVSLLLR root "7.1.2.2 (82.2%) 4.2.1.51 (3.9%) 2.7.11.1 (2.7%)" "H(+)-transporting two-sector ATPase (82.2%) prephenate dehydratase (3.9%) non-specific serine/threonine protein kinase (2.7%)" "GO:0141162 (0.5%) GO:0009094 (0.3%) GO:0046417 (0.3%)" "GO:0005886 (13.5%) GO:0045259 (12.9%) GO:0005829 (1.3%)" "GO:0005524 (14.4%) GO:0043531 (13%) GO:0046933 (12.9%)" "negative regulation of cAMP/PKA signal transduction (0.5%) L-phenylalanine biosynthetic process (0.3%) chorismate metabolic process (0.3%)" "plasma membrane (13.5%) proton-transporting ATP synthase complex (12.9%) cytosol (1.3%)" "ATP binding (14.4%) ADP binding (13%) proton-transporting ATP synthase activity, rotational mechanism (12.9%)" "IPR027417 (8.2%) IPR000194 (7.7%) IPR005294 (7.7%)" "P-loop containing nucleoside triphosphate hydrolase (8.2%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (7.7%) ATP synthase, F1 complex, alpha subunit (7.7%)" LVYLTGTGR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006508 (42.9%) GO:0009279 (14.3%) GO:0008234 (42.9%) proteolysis (42.9%) cell outer membrane (14.3%) cysteine-type peptidase activity (42.9%) "IPR000200 (18.8%) IPR038765 (18.8%) IPR044934 (18.8%)" "Peptidase C10, streptopain (18.8%) Papain-like cysteine peptidase superfamily (18.8%) Peptidase C10, streptopain superfmaily (18.8%)" NTLAVDGTNLYVCQGDGGLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) SLDMLNAR root "GO:0044718 (9.8%) GO:0007608 (4.9%) GO:0006298 (2.4%)" "GO:0009279 (9.8%) GO:0017071 (4.9%) GO:0005886 (3.7%)" "GO:0015344 (9.8%) GO:0005222 (4.9%) GO:0005223 (4.9%)" "siderophore transmembrane transport (9.8%) sensory perception of smell (4.9%) mismatch repair (2.4%)" "cell outer membrane (9.8%) intracellular cyclic nucleotide activated cation channel complex (4.9%) plasma membrane (3.7%)" "siderophore uptake transmembrane transporter activity (9.8%) intracellularly cAMP-activated cation channel activity (4.9%) intracellularly cGMP-activated cation channel activity (4.9%)" "IPR000531 (6.1%) IPR008969 (6.1%) IPR012910 (6.1%)" "TonB-dependent receptor-like, beta-barrel (6.1%) Carboxypeptidase-like, regulatory domain superfamily (6.1%) TonB-dependent receptor, plug domain (6.1%)" STELCFQGANGQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR001611 (20%) IPR013783 (20%) IPR024361 (20%)" "Leucine-rich repeat (20%) Immunoglobulin-like fold (20%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (20%)" QEALDFMYAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (52.9%) IPR042278 (47.1%)" "Fimbrillin-like 1 (52.9%) Fimbrillin-like 1, N-terminal (47.1%)" VFVAGSSWPPDENLFLPFFNEHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.99.12 (100%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (100%) "GO:0009245 (25.2%) GO:0009244 (24.3%)" GO:0005886 (25.2%) "GO:0016740 (19.6%) GO:0043842 (5.6%)" "lipid A biosynthetic process (25.2%) lipopolysaccharide core region biosynthetic process (24.3%)" plasma membrane (25.2%) "transferase activity (19.6%) Kdo transferase activity (5.6%)" "IPR007507 (34.2%) IPR039901 (34.2%) IPR038107 (31.6%)" "3-deoxy-D-manno-octulosonic-acid transferase, N-terminal (34.2%) 3-deoxy-D-manno-octulosonic acid transferase (34.2%) 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily (31.6%)" KSLEDPQVQFFFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.1%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.1%)" VEVVLLPLRDGLTLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (33.3%) "GO:0008171 (33.3%) GO:0008757 (33.3%)" methylation (33.3%) "O-methyltransferase activity (33.3%) S-adenosylmethionine-dependent methyltransferase activity (33.3%)" "IPR002935 (33.8%) IPR050362 (33.8%) IPR029063 (32.3%)" "Class I-like SAM-dependent O-methyltransferase (33.8%) Cation-dependent O-methyltransferase (33.8%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (32.3%)" RDEMNAWSYQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (33.3%) IPR023996 (33.3%) IPR037066 (33.3%)" "TonB-dependent receptor, plug domain (33.3%) TonB-dependent outer membrane protein, SusC/RagA (33.3%) TonB-dependent receptor, plug domain superfamily (33.3%)" TGLQLGFKPAGGLNTVHDAVVYYTLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" FTDNLFLLGSSLQTPWQSWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" YCTQLPNTTLPSFVFYANLPQYVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (30.2%) "GO:0005525 (30.2%) GO:0043022 (30.2%) GO:0016787 (9.5%)" ribosome biogenesis (30.2%) "GTP binding (30.2%) ribosome binding (30.2%) hydrolase activity (9.5%)" "IPR005225 (14.3%) IPR006073 (14.3%) IPR015946 (14.3%)" "Small GTP-binding domain (14.3%) GTP binding domain (14.3%) K homology domain-like, alpha/beta (14.3%)" YLSGVNVVNWPLGR Bacteria Bacteria "2.4.-.- (50%) 2.4.1.54 (50%)" "Glycosyltransferases (50%) undecaprenyl-phosphate mannosyltransferase (50%)" GO:0009247 (33.3%) GO:0016020 (33.3%) GO:0004582 (33.3%) glycolipid biosynthetic process (33.3%) membrane (33.3%) dolichyl-phosphate beta-D-mannosyltransferase activity (33.3%) "IPR001173 (34.5%) IPR039528 (34.5%) IPR029044 (31%)" "Glycosyltransferase 2-like (34.5%) DPM1-like (34.5%) Nucleotide-diphospho-sugar transferases (31%)" ELVDFLK root "3.4.24.- (86.8%) 3.5.4.38 (1.5%) 6.1.1.15 (1.3%)" "Metalloendopeptidases (86.8%) single-stranded DNA cytosine deaminase (1.5%) proline--tRNA ligase (1.3%)" "GO:0006508 (9.8%) GO:0030163 (9.2%) GO:0051301 (3.3%)" "GO:0005886 (9.2%) GO:0005737 (0.7%) GO:0016020 (0.5%)" "GO:0005524 (10.8%) GO:0016887 (10.3%) GO:0004176 (10.3%)" "proteolysis (9.8%) protein catabolic process (9.2%) cell division (3.3%)" "plasma membrane (9.2%) cytoplasm (0.7%) membrane (0.5%)" "ATP binding (10.8%) ATP hydrolysis activity (10.3%) ATP-dependent peptidase activity (10.3%)" "IPR027417 (9.7%) IPR003959 (9.4%) IPR003593 (9.4%)" "P-loop containing nucleoside triphosphate hydrolase (9.7%) ATPase, AAA-type, core (9.4%) AAA+ ATPase domain (9.4%)" TFEELLTFFER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR008886 (34%) IPR023214 (33%) IPR029058 (33%)" "Uncharacterised protein family UPF0227/Esterase YqiA (34%) HAD superfamily (33%) Alpha/Beta hydrolase fold (33%)" YKEEHFTFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LNETPEFCPVCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0008237 (100%) metallopeptidase activity (100%) "IPR019026 (25%) IPR024079 (25%) IPR032625 (25%)" "Peptidase M64, IgA (25%) Metallopeptidase, catalytic domain superfamily (25%) Peptidase M64, N-terminal (25%)" NHGYYVEGNFTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR031965 (50%)" "Immunoglobulin-like fold (50%) Starch-binding module 26 (50%)" LPTEGHLGATLSWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (47.8%) "GO:0004553 (47.8%) GO:0016787 (4.3%)" carbohydrate metabolic process (47.8%) "hydrolase activity, hydrolyzing O-glycosyl compounds (47.8%) hydrolase activity (4.3%)" "IPR046780 (23.3%) IPR032291 (20%) IPR050727 (20%)" "Atrophied bacterial Ig domain (23.3%) Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (20%) Glycosyl hydrolase 43 family arabinanases (20%)" TTDKTVFEHSPWAFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) "IPR011701 (35.5%) IPR050375 (35.5%) IPR036259 (29%)" "Major facilitator superfamily (35.5%) Major Facilitator Superfamily TsgA-like (35.5%) MFS transporter superfamily (29%)" FFSEDYEGLCDDLQELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" YAFEGNATLESFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.7%) IPR025896 (16.7%) IPR026906 (16.7%)" "Peptidase C10, streptopain (16.7%) Spi protease inhibitor (16.7%) BspA-type LRR region (16.7%)" YLDEHDALKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.3%) IPR003156 (9.3%) IPR012947 (9.3%)" "Alanine-tRNA ligase, class IIc (9.3%) DHHA1 domain (9.3%) Threonyl/alanyl tRNA synthetase, SAD (9.3%)" LGFDLDLK root "3.2.1.22 (71.9%) 2.7.13.3 (15.6%) 3.6.5.3 (4.7%)" "alpha-galactosidase (71.9%) histidine kinase (15.6%) protein-synthesizing GTPase (4.7%)" "GO:0016052 (21.3%) GO:0016036 (2.9%) GO:0070125 (1.9%)" "GO:0005886 (3.4%) GO:0005739 (2.4%) GO:0005829 (1.9%)" "GO:0004557 (21.3%) GO:0005524 (4.8%) GO:0000155 (3.9%)" "carbohydrate catabolic process (21.3%) cellular response to phosphate starvation (2.9%) mitochondrial translational elongation (1.9%)" "plasma membrane (3.4%) mitochondrion (2.4%) cytosol (1.9%)" "alpha-galactosidase activity (21.3%) ATP binding (4.8%) phosphorelay sensor kinase activity (3.9%)" "IPR031705 (8.4%) IPR002252 (8.2%) IPR013780 (8.2%)" "Glycosyl hydrolase family 36, C-terminal (8.4%) Glycoside hydrolase family 36 (8.2%) Glycosyl hydrolase, all-beta (8.2%)" LALQALSK root "5.3.1.6 (14.3%) 5.4.99.5 (14.3%) 2.4.1.- (7.1%)" "ribose-5-phosphate isomerase (14.3%) chorismate mutase (14.3%) Hexosyltransferases (7.1%)" "GO:0005975 (7.1%) GO:0015031 (2%) GO:0006891 (1.8%)" "GO:0016020 (5.6%) GO:0005615 (3.8%) GO:0005737 (3%)" "GO:0001681 (6.7%) GO:0015562 (2.8%) GO:0005524 (1.6%)" "carbohydrate metabolic process (7.1%) protein transport (2%) intra-Golgi vesicle-mediated transport (1.8%)" "membrane (5.6%) extracellular space (3.8%) cytoplasm (3%)" "sialate O-acetylesterase activity (6.7%) efflux transmembrane transporter activity (2.8%) ATP binding (1.6%)" "IPR039329 (4.9%) IPR005181 (4.8%) IPR036514 (4.7%)" "Sialate O-acetylesterase (4.9%) Sialate O-acetylesterase domain (4.8%) SGNH hydrolase superfamily (4.7%)" STVGTTTELYDYLR root 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) "GO:0006289 (11.8%) GO:0009432 (2.5%) GO:0006281 (0.5%)" "GO:0005737 (12.3%) GO:0009380 (11.8%) GO:0005829 (0%)" "GO:0003677 (12.3%) GO:0005524 (12.3%) GO:0008270 (12.1%)" "nucleotide-excision repair (11.8%) SOS response (2.5%) DNA repair (0.5%)" "cytoplasm (12.3%) excinuclease repair complex (11.8%) cytosol (0%)" "DNA binding (12.3%) ATP binding (12.3%) zinc ion binding (12.1%)" "IPR027417 (14.5%) IPR041102 (14.5%) IPR041552 (14.3%)" "P-loop containing nucleoside triphosphate hydrolase (14.5%) UvrA, interaction domain (14.5%) UvrA DNA-binding domain (14.3%)" ALRGELPLEVQDLEDDLAGLTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" FAWQSATLFNTPSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) LAEEGYVLESDDSFNFSTHNETSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.6%) IPR033985 (34.6%) IPR011990 (30.9%)" "RagB/SusD domain (34.6%) SusD-like, N-terminal (34.6%) Tetratricopeptide-like helical domain superfamily (30.9%)" EEQLNPVR root "GO:0006465 (5.3%) GO:0033619 (5.3%)" "GO:0005886 (10.5%) GO:0098553 (5.3%) GO:0098554 (5.3%)" "GO:0016757 (26.3%) GO:0003924 (10.5%) GO:0005246 (10.5%)" "signal peptide processing (5.3%) membrane protein proteolysis (5.3%)" "plasma membrane (10.5%) lumenal side of endoplasmic reticulum membrane (5.3%) cytoplasmic side of endoplasmic reticulum membrane (5.3%)" "glycosyltransferase activity (26.3%) GTPase activity (10.5%) calcium channel regulator activity (10.5%)" "IPR000836 (23.6%) IPR017932 (22.2%) IPR029057 (22.2%)" "Phosphoribosyltransferase domain (23.6%) Glutamine amidotransferase type 2 domain (22.2%) Phosphoribosyltransferase-like (22.2%)" GGFLAEAEYLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR010870 (50.7%) IPR023614 (49.3%)" "Phosphate-selective porin O/P (50.7%) Porin domain superfamily (49.3%)" SLYVTSGHYAHYGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.8%) IPR002320 (7.8%) IPR004095 (7.8%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.8%) Threonine-tRNA ligase, class IIa (7.8%) TGS (7.8%)" ATQDANVALDTQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (25%) GO:0005886 (25%) "GO:0010181 (25%) GO:0016655 (25%)" sodium ion transport (25%) plasma membrane (25%) "FMN binding (25%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (25%)" "IPR007329 (50%) IPR010204 (50%)" "FMN-binding (50%) Na(+)-translocating NADH-quinone reductase subunit C (50%)" NVLHFYYLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (38.6%) GO:0089702 (11.4%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (38.6%) undecaprenyl-phosphate glucose phosphotransferase activity (11.4%)" "IPR003362 (35%) IPR017475 (34%) IPR017473 (31%)" "Bacterial sugar transferase (35%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (34%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (31%)" DLHLEQLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000270 (33.3%) GO:0016020 (33.3%) GO:0008933 (33.3%) peptidoglycan metabolic process (33.3%) membrane (33.3%) peptidoglycan lytic transglycosylase activity (33.3%) "IPR018392 (21.3%) IPR000189 (20.5%) IPR008258 (20.5%)" "LysM domain (21.3%) Prokaryotic transglycosylase, active site (20.5%) Transglycosylase SLT domain 1 (20.5%)" FSSDMDAVTAMTLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (18.6%) GO:0005886 (18.3%)" "GO:0005524 (18.6%) GO:0043531 (18.6%) GO:0046933 (18.6%)" "proton-transporting ATP synthase complex (18.6%) plasma membrane (18.3%)" "ATP binding (18.6%) ADP binding (18.6%) proton-transporting ATP synthase activity, rotational mechanism (18.6%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" HLVPEELESTGLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.7%) GO:0034605 (12.2%)" GO:0005737 (12.2%) "GO:0004176 (12.7%) GO:0004252 (12.7%) GO:0005524 (12.7%)" "protein quality control for misfolded or incompletely synthesized proteins (12.7%) cellular response to heat (12.2%)" cytoplasm (12.2%) "ATP-dependent peptidase activity (12.7%) serine-type endopeptidase activity (12.7%) ATP binding (12.7%)" "IPR003593 (7.5%) IPR003959 (7.5%) IPR027065 (7.5%)" "AAA+ ATPase domain (7.5%) ATPase, AAA-type, core (7.5%) Lon protease (7.5%)" EQDDPLFQESLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR038726 (34.7%) IPR011604 (32.7%) IPR027417 (32.7%)" "PD-(D/E)XK endonuclease-like domain, AddAB-type (34.7%) PD-(D/E)XK endonuclease-like domain superfamily (32.7%) P-loop containing nucleoside triphosphate hydrolase (32.7%)" VLNSGLDFELGWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR023996 (14.2%) IPR039426 (14.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent receptor-like (14.2%)" DGDVAGLSAFQGDAALLSLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" DVVLQCCASGGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR031704 (12.9%) IPR031705 (12.9%)" "Glycoside hydrolase family 36 (12.9%) Glycosyl hydrolase family 36, N-terminal (12.9%) Glycosyl hydrolase family 36, C-terminal (12.9%)" HHLMVNAHEATRPTGLCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.22 (60%) 3.2.1.- (20%) 3.2.1.20 (20%)" "alpha-galactosidase (60%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (20%) alpha-glucosidase (20%)" "GO:0030246 (56.8%) GO:0016787 (40.2%) GO:0004557 (1.5%)" "carbohydrate binding (56.8%) hydrolase activity (40.2%) alpha-galactosidase activity (1.5%)" "IPR019563 (14.5%) IPR029483 (14.5%) IPR029486 (14.5%)" "Glycosyl-hydrolase 97, catalytic domain (14.5%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.5%) Glycosyl-hydrolase 97, N-terminal domain (14.5%)" YQLGDALR root "3.1.13.1 (97.7%) 3.1.3.16 (2.3%)" "exoribonuclease II (97.7%) protein-serine/threonine phosphatase (2.3%)" "GO:0006402 (21.8%) GO:0000160 (0.5%) GO:0006298 (0.5%)" "GO:0005829 (21.8%) GO:0005886 (1.6%) GO:0005634 (0.5%)" "GO:0003723 (21.8%) GO:0008859 (21.8%) GO:0042910 (1.6%)" "mRNA catabolic process (21.8%) phosphorelay signal transduction system (0.5%) mismatch repair (0.5%)" "cytosol (21.8%) plasma membrane (1.6%) nucleus (0.5%)" "RNA binding (21.8%) exoribonuclease II activity (21.8%) xenobiotic transmembrane transporter activity (1.6%)" "IPR001900 (11.1%) IPR003029 (11.1%) IPR004476 (11.1%)" "Ribonuclease II/R (11.1%) S1 domain (11.1%) Ribonuclease II/ribonuclease R (11.1%)" MYFAQDNYPEAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.6%) IPR033985 (34.6%) IPR011990 (30.8%)" "RagB/SusD domain (34.6%) SusD-like, N-terminal (34.6%) Tetratricopeptide-like helical domain superfamily (30.8%)" EYEVSCEELDFLNDVAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (20%) GO:0005829 (20%) "GO:0004335 (20%) GO:0005524 (20%) GO:0046872 (20%)" galactose metabolic process (20%) cytosol (20%) "galactokinase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR013750 (10.4%) IPR000705 (10.1%) IPR006203 (10.1%)" "GHMP kinase, C-terminal domain (10.4%) Galactokinase (10.1%) GHMP kinase, ATP-binding, conserved site (10.1%)" EGAGWALPEKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" AGQEVLVQLVKEPLSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.8%) IPR004659 (25.8%) IPR019307 (25.8%)" "S1 domain (25.8%) Ribonuclease E/G (25.8%) RNA-binding protein AU-1/Ribonuclease E/G (25.8%)" YVLPYDYPDMDSSLMHLYLLEAGDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.9 (97.6%) 1.6.5.- (2.4%)" "NADH:ubiquinone reductase (non-electrogenic) (97.6%) With a quinone or similar compound as acceptor (2.4%)" GO:0003954 (100%) NADH dehydrogenase activity (100%) "IPR023753 (25.5%) IPR045024 (25.5%) IPR054585 (24.8%)" "FAD/NAD(P)-binding domain (25.5%) Alternative NADH dehydrogenase (25.5%) External alternative NADH-ubiquinone oxidoreductase-like, C-terminal domain (24.8%)" VKGNVDGCSVMLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (47.2%) GO:0030313 (41.7%) "GO:0016209 (5.6%) GO:0016491 (5.6%)" cytochrome complex assembly (47.2%) cell envelope (41.7%) "antioxidant activity (5.6%) oxidoreductase activity (5.6%)" "IPR013766 (20.5%) IPR025380 (20.5%) IPR050553 (20.5%)" "Thioredoxin domain (20.5%) Domain of unknown function DUF4369 (20.5%) Thioredoxin family ResA/DsbE subfamily (20.5%)" SYGHQAGVDTVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.5.1.- (92.5%) 2.5.1.31 (7.5%)" "Transferring alkyl or aryl groups, other than methyl groups (92.5%) ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] (7.5%)" GO:0016094 (33%) "GO:0000287 (33%) GO:0045547 (33%) GO:0016765 (0.9%)" polyprenol biosynthetic process (33%) "magnesium ion binding (33%) ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity (33%) transferase activity, transferring alkyl or aryl (other than methyl) groups (0.9%)" "IPR001441 (33.9%) IPR018520 (33%) IPR036424 (33%)" "Decaprenyl diphosphate synthase-like (33.9%) Di-trans-poly-cis-decaprenylcistransferase-like, conserved site (33%) Decaprenyl diphosphate synthase-like superfamily (33%)" YYPVFELGYGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR046111 (100%) Protein of unknown function DUF6048 (100%) GSLNVDMGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) GWDGKDQVLFNNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032342 (100%) Protein of unknown function DUF4861 (100%) LGALCAAPMVLASTGLLEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (100%) cytoplasm (100%) "IPR002818 (25%) IPR006287 (25%) IPR029062 (25%)" "DJ-1/PfpI (25%) Protein/nucleic acid deglycase DJ-1 (25%) Class I glutamine amidotransferase-like (25%)" YLETLWWLLK root 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) "GO:0006428 (14.3%) GO:0006508 (0%)" "GO:0005737 (14.3%) GO:0016020 (0%)" "GO:0004822 (14.4%) GO:0005524 (14.4%) GO:0002161 (14.3%)" "isoleucyl-tRNA aminoacylation (14.3%) proteolysis (0%)" "cytoplasm (14.3%) membrane (0%)" "isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%) aminoacyl-tRNA deacylase activity (14.3%)" "IPR002300 (12.6%) IPR002301 (12.6%) IPR023586 (12.6%)" "Aminoacyl-tRNA synthetase, class Ia (12.6%) Isoleucine-tRNA ligase (12.6%) Isoleucine-tRNA ligase, type 2 (12.6%)" ETPYEGEDR Pseudomonadati Bacteria Pseudomonadati 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20.5%) IPR006124 (20.5%) IPR017850 (20.5%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20.5%) Metalloenzyme (20.5%) Alkaline-phosphatase-like, core domain superfamily (20.5%)" SYLQSDSNVK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006457 (0.1%) GO:0006974 (0.1%) GO:0009408 (0.1%)" "GO:0005737 (3.3%) GO:0005829 (0.1%)" "GO:0005524 (23.7%) GO:0016887 (23.7%) GO:0051082 (23.7%)" "protein folding (0.1%) DNA damage response (0.1%) response to heat (0.1%)" "cytoplasm (3.3%) cytosol (0.1%)" "ATP binding (23.7%) ATP hydrolysis activity (23.7%) unfolded protein binding (23.7%)" "IPR001404 (17.9%) IPR020568 (17.9%) IPR020575 (17.5%)" "Heat shock protein Hsp90 family (17.9%) Ribosomal protein uS5 domain 2-type superfamily (17.9%) Heat shock protein Hsp90, N-terminal (17.5%)" KLVNVVLK root "6.1.1.4 (96.4%) 2.7.13.3 (1.8%) 3.1.-.- (1.8%)" "leucine--tRNA ligase (96.4%) histidine kinase (1.8%) Acting on ester bonds (1.8%)" "GO:0006429 (15.5%) GO:0000070 (1.5%) GO:0001732 (0.3%)" "GO:0005829 (15.8%) GO:0016020 (3.4%) GO:0000796 (1.5%)" "GO:0005524 (15.8%) GO:0002161 (15.5%) GO:0004823 (15.5%)" "leucyl-tRNA aminoacylation (15.5%) mitotic sister chromatid segregation (1.5%) formation of cytoplasmic translation initiation complex (0.3%)" "cytosol (15.8%) membrane (3.4%) condensin complex (1.5%)" "ATP binding (15.8%) aminoacyl-tRNA deacylase activity (15.5%) leucine-tRNA ligase activity (15.5%)" "IPR001412 (9.4%) IPR002302 (9.4%) IPR013155 (9.4%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.4%) Leucine-tRNA ligase (9.4%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (9.4%)" SESAYNTGLTTNNPTPSAPVDNDAEYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" YFLAAEEQLEGTEYQLMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (23.9%) GO:0005737 (23.9%) "GO:0046872 (26.1%) GO:0070006 (23.9%) GO:0016787 (2.2%)" proteolysis (23.9%) cytoplasm (23.9%) "metal ion binding (26.1%) metalloaminopeptidase activity (23.9%) hydrolase activity (2.2%)" "IPR000587 (13.3%) IPR050422 (13.3%) IPR029149 (12.8%)" "Creatinase, N-terminal (13.3%) Xaa-Pro aminopeptidase P (13.3%) Creatinase/Aminopeptidase P/Spt16, N-terminal (12.8%)" QCLVGVLFDGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) IPR039498 (100%) Uncharacterised nucleotidyltransferase (100%) RYFAQNNLTVYYLNATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.5%) GO:0022900 (14.5%) GO:0044281 (13.2%)" "GO:0005506 (14.5%) GO:0030976 (14.5%) GO:0051539 (14.5%)" "response to oxidative stress (14.5%) electron transport chain (14.5%) small molecule metabolic process (13.2%)" "iron ion binding (14.5%) thiamine pyrophosphate binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" MQELLDAR root "2.7.11.1 (22.2%) 1.1.1.193 (11.1%) 1.4.3.16 (11.1%)" "non-specific serine/threonine protein kinase (22.2%) 5-amino-6-(5-phosphoribosylamino)uracil reductase (11.1%) L-aspartate oxidase (11.1%)" "GO:0006281 (1.1%) GO:0006325 (1.1%) GO:0006633 (1.1%)" "GO:0000781 (1.1%) GO:0005634 (1.1%) GO:0005829 (1.1%)" "GO:0005524 (30.9%) GO:0016301 (25.5%) GO:0004674 (2.1%)" "DNA repair (1.1%) chromatin organization (1.1%) fatty acid biosynthetic process (1.1%)" "chromosome, telomeric region (1.1%) nucleus (1.1%) cytosol (1.1%)" "ATP binding (30.9%) kinase activity (25.5%) protein serine/threonine kinase activity (2.1%)" "IPR006083 (15.5%) IPR027417 (15.5%) IPR018163 (14.9%)" "Phosphoribulokinase/uridine kinase (15.5%) P-loop containing nucleoside triphosphate hydrolase (15.5%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (14.9%)" LSLLDTHPVLGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009306 (50%) GO:0005886 (50%) protein secretion (50%) plasma membrane (50%) IPR007452 (100%) Translocation and assembly module TamB, C-terminal domain (100%) AYDETLNKVTEHQVVEGTVLSVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" SFYEETVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.2%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.2%)" FSHLLLGDDLWGGALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR043864 (27.2%) IPR016035 (25.4%) IPR002641 (23.7%)" "OMP85-like, membrane spanning beta-barrel domain (27.2%) Acyl transferase/acyl hydrolase/lysophospholipase (25.4%) Patatin-like phospholipase domain (23.7%)" LQLLNGPNLNLLGVR Bacteroidota Bacteria Pseudomonadati Bacteroidota 4.2.1.10 (100%) 3-dehydroquinate dehydratase (100%) "GO:0008652 (19.5%) GO:0009073 (19.5%) GO:0009423 (19.5%)" GO:0016020 (2.2%) GO:0003855 (19.7%) "amino acid biosynthetic process (19.5%) aromatic amino acid family biosynthetic process (19.5%) chorismate biosynthetic process (19.5%)" membrane (2.2%) 3-dehydroquinate dehydratase activity (19.7%) "IPR036441 (33.5%) IPR001874 (33.2%) IPR018509 (33.2%)" "Dehydroquinase, class II superfamily (33.5%) Dehydroquinase, class II (33.2%) Dehydroquinase, class II, conserved site (33.2%)" RFDEDDYVVNLGPNHPSTHGVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.6.5.11 (66.7%) 1.6.5.9 (33.3%)" "Transferred entry: 1.6.5.9 (66.7%) NADH:ubiquinone reductase (non-electrogenic) (33.3%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" YPELDMVSFGPTLR Pseudomonadati Bacteria Pseudomonadati 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (34.6%) IPR002933 (34.6%) IPR011650 (30.9%)" "Peptidase M20C, Xaa-His dipeptidase (34.6%) Peptidase M20 (34.6%) Peptidase M20, dimerisation domain (30.9%)" APFGSLER root 6.1.1.3 (100%) threonine--tRNA ligase (100%) "GO:0006435 (16.6%) GO:0006013 (0%) GO:0006413 (0%)" GO:0005737 (16.6%) "GO:0004829 (16.6%) GO:0005524 (16.6%) GO:0046872 (16.5%)" "threonyl-tRNA aminoacylation (16.6%) mannose metabolic process (0%) translational initiation (0%)" cytoplasm (16.6%) "threonine-tRNA ligase activity (16.6%) ATP binding (16.6%) metal ion binding (16.5%)" "IPR002314 (8.3%) IPR002320 (8.3%) IPR045864 (8.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (8.3%) Threonine-tRNA ligase, class IIa (8.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (8.3%)" SFELSSMGLR root 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (17.9%) GO:0006529 (2.2%)" GO:0005829 (20.1%) "GO:0004071 (20.1%) GO:0005524 (17.9%) GO:0016740 (9.7%)" "L-asparagine biosynthetic process (17.9%) obsolete asparagine biosynthetic process (2.2%)" cytosol (20.1%) "aspartate-ammonia ligase activity (20.1%) ATP binding (17.9%) transferase activity (9.7%)" "IPR004618 (33.5%) IPR006195 (33.5%) IPR045864 (33%)" "Aspartate--ammonia ligase (33.5%) Aminoacyl-tRNA synthetase, class II (33.5%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (33%)" ADGTSYEACLNTHGAPLGGDAYVNTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.2.1.1 (96.7%) 2.2.1.- (3.3%)" "transketolase (96.7%) Transketolases and transaldolases (3.3%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005474 (12.5%) IPR005475 (12.5%) IPR009014 (12.5%)" "Transketolase, N-terminal (12.5%) Transketolase-like, pyrimidine-binding domain (12.5%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.5%)" KACEDFFNENANNGNPYHLVEPTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EVLSGLNK root "5.6.2.4 (40%) 1.3.8.- (20%) 2.3.2.26 (20%)" "DNA 3'-5' helicase (40%) With a flavin as acceptor (20%) HECT-type E3 ubiquitin transferase (20%)" "GO:0050821 (5.7%) GO:0006635 (2.5%) GO:0051083 (2.5%)" "GO:0005829 (8.3%) GO:1990281 (5.7%) GO:0016020 (5.1%)" "GO:0015562 (5.7%) GO:0051082 (5.7%) GO:0003677 (3.2%)" "protein stabilization (5.7%) fatty acid beta-oxidation (2.5%) 'de novo' cotranslational protein folding (2.5%)" "cytosol (8.3%) efflux pump complex (5.7%) membrane (5.1%)" "efflux transmembrane transporter activity (5.7%) unfolded protein binding (5.7%) DNA binding (3.2%)" "IPR006143 (5.2%) IPR005632 (4.7%) IPR024930 (4.7%)" "RND efflux pump, membrane fusion protein (5.2%) Chaperone protein Skp (4.7%) Skp domain superfamily (4.7%)" LVWNDEFNEGSELNSTDWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.103 (100%) keratan-sulfate endo-1,4-beta-galactosidase (100%) GO:0005975 (50%) "GO:0004553 (47.9%) GO:0033930 (2.1%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (47.9%) keratan-sulfate endo-1,4-beta-galactosidase activity (2.1%)" "IPR000757 (21.1%) IPR024361 (21.1%) IPR050546 (21.1%)" "Beta-glucanase-like, N-terminal domain (21.1%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.1%) Glycosyl Hydrolase Family 16 (21.1%)" FLQLADK root "2.3.3.13 (52.5%) 1.1.1.35 (4.9%) 4.2.1.17 (4.9%)" "2-isopropylmalate synthase (52.5%) 3-hydroxyacyl-CoA dehydrogenase (4.9%) enoyl-CoA hydratase (4.9%)" "GO:0009098 (7%) GO:0045493 (1.2%) GO:0000272 (1.1%)" "GO:0005737 (7.8%) GO:0005829 (4.7%) GO:0016020 (2.1%)" "GO:0003852 (7%) GO:0030145 (6.8%) GO:0003985 (6.5%)" "L-leucine biosynthetic process (7%) xylan catabolic process (1.2%) polysaccharide catabolic process (1.1%)" "cytoplasm (7.8%) cytosol (4.7%) membrane (2.1%)" "2-isopropylmalate synthase activity (7%) manganese ion binding (6.8%) acetyl-CoA C-acetyltransferase activity (6.5%)" "IPR013785 (3.9%) IPR050073 (3.9%) IPR054691 (3.9%)" "Aldolase-type TIM barrel (3.9%) 2-IPM synthase/homocitrate synthase-like (3.9%) 2-isopropylmalate synthase/homocitrate synthase, post-catalytic domain (3.9%)" DNEQVLDHLMDEFGVTGPNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (52.1%) IPR029052 (47.9%)" "Fructose-1,6-bisphosphatase class 3 (52.1%) Metallo-dependent phosphatase-like (47.9%)" ANMVEYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (21.4%) IPR024361 (21.4%) IPR050386 (21.4%)" "Glycoside hydrolase, family 5 (21.4%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.4%) Glycosyl Hydrolase 5 (Cellulase A) (21.4%)" YLTPDNWADAAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TSVDLFLLHEGTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR011990 (25%) IPR013105 (25%) IPR019734 (25%)" "Tetratricopeptide-like helical domain superfamily (25%) Tetratricopeptide repeat 2 (25%) Tetratricopeptide repeat (25%)" YFYQLDGEGLR root 2.7.7.39 (100%) glycerol-3-phosphate cytidylyltransferase (100%) "GO:0000166 (45.2%) GO:0016779 (40.4%) GO:0016491 (10.1%)" "nucleotide binding (45.2%) nucleotidyltransferase activity (40.4%) oxidoreductase activity (10.1%)" "IPR000683 (20.2%) IPR004821 (20%) IPR014729 (19.8%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (20.2%) Cytidyltransferase-like domain (20%) Rossmann-like alpha/beta/alpha sandwich fold (19.8%)" LGTTLNTLDGAVTAAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DLFCPFR root GO:0003676 (100%) nucleic acid binding (100%) "IPR014464 (19.6%) IPR040764 (19.6%) IPR039566 (19.4%)" "Conserved virulence factor B (19.6%) Conserved virulence factor B-like, winged helix domain (19.6%) Conserved virulence factor B, first S1 domain (19.4%)" LGFSNEDVLYMLMPDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.8%) IPR015171 (14.8%) IPR019492 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Cyclomaltodextrinase, N-terminal (14.8%) Cyclo-malto-dextrinase, C-terminal (14.8%)" SALLSAAQQEEYRAELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.2%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.2%)" DLQYLSAEEVESVSVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" LDAPVNTAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (69.8%) "GO:0016787 (25.6%) GO:0016829 (4.7%)" carbohydrate metabolic process (69.8%) "hydrolase activity (25.6%) lyase activity (4.7%)" "IPR013783 (24.6%) IPR031965 (24.6%) IPR017853 (23.1%)" "Immunoglobulin-like fold (24.6%) Starch-binding module 26 (24.6%) Glycoside hydrolase superfamily (23.1%)" FAGALNTYTLEAMMQDGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (19.9%) "GO:0005737 (19.9%) GO:0017101 (19.9%)" "GO:0004827 (19.9%) GO:0005524 (19.9%) GO:0016874 (0.3%)" prolyl-tRNA aminoacylation (19.9%) "cytoplasm (19.9%) aminoacyl-tRNA synthetase multienzyme complex (19.9%)" "proline-tRNA ligase activity (19.9%) ATP binding (19.9%) ligase activity (0.3%)" "IPR002314 (11.3%) IPR004499 (11.3%) IPR006195 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Proline-tRNA ligase, class IIa, archaeal-type (11.3%) Aminoacyl-tRNA synthetase, class II (11.3%)" SGFGVTTMSSFFTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.7%) IPR039426 (14.7%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.7%) TonB-dependent receptor-like (14.7%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" QLQAYVQAYDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (46%) GO:0016020 (4%)" GO:0008381 (50%) "plasma membrane (46%) membrane (4%)" mechanosensitive monoatomic ion channel activity (50%) "IPR006685 (17.4%) IPR045275 (17.4%) IPR049278 (17.4%)" "Mechanosensitive ion channel MscS (17.4%) Mechanosensitive ion channel MscS, archaea/bacteria type (17.4%) Mechanosensitive ion channel MscS, C-terminal domain (17.4%)" KTGNFLAMLLQVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NTGFELMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" RPPLTLELEYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (35%) IPR020845 (35%) IPR042099 (30%)" "AMP-dependent synthetase/ligase domain (35%) AMP-binding, conserved site (35%) ANL, N-terminal domain (30%)" LSETQFVDGQEVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NLLGELEYKPLNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (20%) GO:0046912 (5%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (20%) acyltransferase activity, acyl groups converted into alkyl on transfer (5%)" "IPR002020 (20%) IPR016142 (20%) IPR016143 (20%)" "Citrate synthase (20%) Citrate synthase-like, large alpha subdomain (20%) Citrate synthase-like, small alpha subdomain (20%)" FYLEVKDPSFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.5%) IPR005845 (14.5%) IPR005846 (14.5%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.5%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.5%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (14.5%)" EAGESKYPFTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0005886 (50%) GO:0016757 (50%) plasma membrane (50%) glycosyltransferase activity (50%) "IPR001173 (33.9%) IPR050256 (33.9%) IPR029044 (32.3%)" "Glycosyltransferase 2-like (33.9%) Glycosyltransferase 2 (33.9%) Nucleotide-diphospho-sugar transferases (32.3%)" TGSLAGTSALVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR001466 (33.8%) IPR050491 (33.8%) IPR012338 (32.5%)" "Beta-lactamase-related (33.8%) Beta-lactamase AmpC-like (33.8%) Beta-lactamase/transpeptidase-like (32.5%)" LHHLGYR root "2.1.1.216 (23.3%) 5.6.2.4 (15%) 2.7.11.1 (13.3%)" "tRNA (guanine(26)-N(2))-dimethyltransferase (23.3%) DNA 3'-5' helicase (15%) non-specific serine/threonine protein kinase (13.3%)" "GO:0006355 (14.8%) GO:0006281 (13.8%) GO:0046491 (1.2%)" "GO:0005634 (15.4%) GO:0035267 (14.9%) GO:0000124 (14.8%)" "GO:0004674 (7.1%) GO:0004493 (1.2%) GO:0003755 (0.8%)" "regulation of DNA-templated transcription (14.8%) DNA repair (13.8%) L-methylmalonyl-CoA metabolic process (1.2%)" "nucleus (15.4%) NuA4 histone acetyltransferase complex (14.9%) SAGA complex (14.8%)" "protein serine/threonine kinase activity (7.1%) methylmalonyl-CoA epimerase activity (1.2%) peptidyl-prolyl cis-trans isomerase activity (0.8%)" "IPR003151 (8.7%) IPR050517 (8.7%) IPR014009 (8.6%)" "PIK-related kinase, FAT (8.7%) DNA Damage Response and Repair Kinase (8.7%) PIK-related kinase, FAT domain (8.6%)" LPTLLFDELDTGVSGK Bacteria Bacteria "GO:0006310 (20%) GO:0009432 (20%) GO:0006281 (19.8%)" GO:0043590 (19.8%) "GO:0005524 (20%) GO:0016887 (0.2%)" "DNA recombination (20%) SOS response (20%) DNA repair (19.8%)" bacterial nucleoid (19.8%) "ATP binding (20%) ATP hydrolysis activity (0.2%)" "IPR004604 (33.5%) IPR003395 (32.9%) IPR027417 (32.6%)" "DNA recombination/repair protein RecN (33.5%) RecF/RecN/SMC, N-terminal (32.9%) P-loop containing nucleoside triphosphate hydrolase (32.6%)" EVLDYYDK root "GO:0005975 (28.8%) GO:0045493 (13.6%) GO:0006351 (1.1%)" "GO:0005634 (1.1%) GO:0009279 (0.6%) GO:0030313 (0.6%)" "GO:0016787 (29.9%) GO:0046559 (13.6%) GO:0003677 (1.7%)" "carbohydrate metabolic process (28.8%) xylan catabolic process (13.6%) DNA-templated transcription (1.1%)" "nucleus (1.1%) cell outer membrane (0.6%) cell envelope (0.6%)" "hydrolase activity (29.9%) alpha-glucuronidase activity (13.6%) DNA binding (1.7%)" "IPR031924 (20.6%) IPR041437 (20.6%) IPR029018 (20.1%)" "Glycosyl hydrolase family 115 (20.6%) Gylcosyl hydrolase 115 C-terminal domain (20.6%) Beta-hexosaminidase-like, domain 2 (20.1%)" LSVKEDLCGCGNLLEQDNTPLADLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (51.1%) IPR036737 (48.9%)" "Domain of unknown function DUF3868 (51.1%) OmpA-like domain superfamily (48.9%)" SFDPANWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR021457 (100%) Protein of unknown function DUF3108 (100%) DLPTHATEEYLEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR019852 (50%) IPR055087 (50%)" "Gliding motility-associated protein, GldL (50%) Gliding motility protein GldL-like, N-terminal domain (50%)" LEGLSGEEEKWLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR043864 (27.2%) IPR016035 (25.4%) IPR002641 (23.7%)" "OMP85-like, membrane spanning beta-barrel domain (27.2%) Acyl transferase/acyl hydrolase/lysophospholipase (25.4%) Patatin-like phospholipase domain (23.7%)" LTQTNFSLSNAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025684 (50%) IPR026377 (50%)" "Gliding motility protein SprA N-terminal domain (50%) Cell surface SprA (50%)" LLEKFEGDANK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (19.9%) GO:0006164 (11.9%) GO:0006189 (7.9%)" "GO:0004044 (19.9%) GO:0046872 (19.9%) GO:0051536 (19.9%)" "purine nucleobase biosynthetic process (19.9%) purine nucleotide biosynthetic process (11.9%) 'de novo' IMP biosynthetic process (7.9%)" "amidophosphoribosyltransferase activity (19.9%) metal ion binding (19.9%) iron-sulfur cluster binding (19.9%)" "IPR000836 (21.5%) IPR017932 (20.3%) IPR029057 (20.3%)" "Phosphoribosyltransferase domain (21.5%) Glutamine amidotransferase type 2 domain (20.3%) Phosphoribosyltransferase-like (20.3%)" AAEGNNFGTVLLPEGLLEFLPALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.4%) GO:0006002 (13.7%)" GO:0005829 (14.4%) "GO:0003872 (14.4%) GO:0005524 (14.4%) GO:0046872 (14.4%)" "response to glucose (14.4%) fructose 6-phosphate metabolic process (13.7%)" cytosol (14.4%) "6-phosphofructokinase activity (14.4%) ATP binding (14.4%) metal ion binding (14.4%)" "IPR000023 (25.6%) IPR011183 (25.6%) IPR022953 (24.4%)" "Phosphofructokinase domain (25.6%) Pyrophosphate-dependent phosphofructokinase PfpB (25.6%) ATP-dependent 6-phosphofructokinase (24.4%)" FLNHTSGADNWHNWNLVVATDADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) NVTFTPVTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) AVLEGLGNSFAWLVNDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.8%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.8%)" "IPR001672 (20.2%) IPR018189 (20.2%) IPR035476 (20.2%)" "Phosphoglucose isomerase (PGI) (20.2%) Phosphoglucose isomerase, conserved site (20.2%) Phosphoglucose isomerase, SIS domain 1 (20.2%)" SPALDSCPQR root "GO:0006412 (20.1%) GO:0032790 (0%)" "GO:0015935 (20.1%) GO:0005840 (0.1%) GO:0009507 (0%)" "GO:0003735 (20.1%) GO:0019843 (20.1%) GO:0000049 (19.3%)" "translation (20.1%) ribosome disassembly (0%)" "small ribosomal subunit (20.1%) ribosome (0.1%) chloroplast (0%)" "structural constituent of ribosome (20.1%) rRNA binding (20.1%) tRNA binding (19.3%)" "IPR006032 (33.2%) IPR012340 (33.2%) IPR005679 (33.1%)" "Small ribosomal subunit protein uS12 (33.2%) Nucleic acid-binding, OB-fold (33.2%) Ribosomal protein uS12, bacteria (33.1%)" VMLSLQGSDVLNYLNAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.21.107 (80%) 3.4.21.- (20%)" "peptidase Do (80%) Serine endopeptidases (20%)" GO:0006508 (49.2%) GO:0016020 (1.6%) GO:0004252 (49.2%) proteolysis (49.2%) membrane (1.6%) serine-type endopeptidase activity (49.2%) "IPR001478 (18.2%) IPR001940 (17.6%) IPR009003 (17.6%)" "PDZ domain (18.2%) Peptidase S1C (17.6%) Peptidase S1, PA clan (17.6%)" VLAAYEYYLLVNNFGGVPLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.7%) IPR033985 (33.7%) IPR011990 (32.6%)" "RagB/SusD domain (33.7%) SusD-like, N-terminal (33.7%) Tetratricopeptide-like helical domain superfamily (32.6%)" LVTEMVEDPETGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (20%) "GO:0016651 (20%) GO:0046872 (20%) GO:0048038 (20%)" membrane (20%) "oxidoreductase activity, acting on NAD(P)H (20%) metal ion binding (20%) quinone binding (20%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" WYYGHVLTYSFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.6%) IPR008969 (48.4%)" "Family of unknown function DUF5686 (51.6%) Carboxypeptidase-like, regulatory domain superfamily (48.4%)" ALDCALNEEDYETASALRDELER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MNLGQLFECLLGAAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.8%) IPR007121 (7.8%) IPR007641 (7.8%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.8%) RNA polymerase, beta subunit, conserved site (7.8%) RNA polymerase Rpb2, domain 7 (7.8%)" VQPYEDSTDKWLVSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0000027 (10%) GO:0009409 (10%) GO:0010467 (10%)" "GO:0005829 (10%) GO:1990904 (10%)" "GO:0000049 (10%) GO:0003924 (10%) GO:0005525 (10%)" "ribosomal large subunit assembly (10%) response to cold (10%) gene expression (10%)" "cytosol (10%) ribonucleoprotein complex (10%)" "tRNA binding (10%) GTPase activity (10%) GTP binding (10%)" "IPR000640 (6.7%) IPR000795 (6.7%) IPR004161 (6.7%)" "Elongation factor EFG, domain V-like (6.7%) Translational (tr)-type GTP-binding domain (6.7%) Translation elongation factor EFTu-like, domain 2 (6.7%)" VTGSTLNVTLNEDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (27.5%) GO:0009279 (45%) GO:0015344 (27.5%) siderophore transmembrane transport (27.5%) cell outer membrane (45%) siderophore uptake transmembrane transporter activity (27.5%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" DSAPVGYSSSPQNTYNATLGLEYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" YAGVNPANGEQLWYDKNGNVTNEFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SQATLVYGQMNEPPGAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (23.3%) GO:0005886 (22.7%)" "GO:0005524 (23.3%) GO:0046933 (23.3%) GO:0016787 (7.3%)" "proton-transporting ATP synthase complex (23.3%) plasma membrane (22.7%)" "ATP binding (23.3%) proton-transporting ATP synthase activity, rotational mechanism (23.3%) hydrolase activity (7.3%)" "IPR000194 (10.1%) IPR005722 (10.1%) IPR050053 (10.1%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.1%) ATP synthase, F1 complex, beta subunit (10.1%) ATPase alpha/beta chains (10.1%)" QLAVDPAWANLADDEAKEDNAPAFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002869 (7.7%) IPR002880 (7.7%) IPR009014 (7.7%)" "Pyruvate-flavodoxin oxidoreductase, central domain (7.7%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.7%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (7.7%)" ATGGYLDVDSFEYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.5%) IPR006584 (12.5%) IPR006710 (12.5%)" "Carbohydrate binding module family 6 (12.5%) Cellulose binding, type IV (12.5%) Glycoside hydrolase, family 43 (12.5%)" TLGERPCFLCDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (97%) GO:0016740 (3%) sporulation resulting in formation of a cellular spore (97%) transferase activity (3%) "IPR046320 (13.1%) IPR001173 (12.7%) IPR013486 (12.7%)" "Domain of unknown function DUF4922 (13.1%) Glycosyltransferase 2-like (12.7%) Sporulation stage II protein D, amidase enhancer LytB (12.7%)" VDDNHVNVLLPAFGEAPMALPSLTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) YGVDTSFVAR Bacteria Bacteria GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" LNLGTWQGLYLCEFR root GO:0016020 (100%) membrane (100%) "IPR001602 (50%) IPR035917 (50%)" "UPF0047 protein YjbQ-like (50%) YjbQ-like superfamily (50%)" EADGLGSTSAAFLLPGSTPWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016798 (48.1%) GO:0030246 (48.1%) GO:0016787 (3.7%)" "hydrolase activity, acting on glycosyl bonds (48.1%) carbohydrate binding (48.1%) hydrolase activity (3.7%)" "IPR019563 (13%) IPR029483 (13%) IPR029486 (13%)" "Glycosyl-hydrolase 97, catalytic domain (13%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (13%) Glycosyl-hydrolase 97, N-terminal domain (13%)" EGLENVFHHLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (19.9%) GO:0006164 (12.8%) GO:0006189 (7.1%)" "GO:0004044 (19.9%) GO:0046872 (19.9%) GO:0051536 (19.9%)" "purine nucleobase biosynthetic process (19.9%) purine nucleotide biosynthetic process (12.8%) 'de novo' IMP biosynthetic process (7.1%)" "amidophosphoribosyltransferase activity (19.9%) metal ion binding (19.9%) iron-sulfur cluster binding (19.9%)" "IPR017932 (21.3%) IPR000836 (20.7%) IPR029055 (20%)" "Glutamine amidotransferase type 2 domain (21.3%) Phosphoribosyltransferase domain (20.7%) Nucleophile aminohydrolases, N-terminal (20%)" ESLWEVNYEDGNNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" AETHNFPTTVEPFNGAATGTGGELRDR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.1%) GO:0006164 (0.9%)" GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" "'de novo' IMP biosynthetic process (19.1%) purine nucleotide biosynthetic process (0.9%)" cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010918 (11.2%) IPR041609 (11.2%) IPR055181 (11.2%)" "PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, linker domain (11.2%) FGAR-AT, PurM N-terminal-like domain (11.2%)" LPQAFVQEVTSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (25%) GO:0043952 (25%) GO:0065002 (25%)" GO:0005886 (25%) "protein targeting (25%) protein transport by the Sec complex (25%) intracellular protein transmembrane transport (25%)" plasma membrane (25%) "IPR002208 (25%) IPR023201 (25%) IPR026593 (25%)" "SecY/SEC61-alpha family (25%) SecY domain superfamily (25%) Protein translocase subunit SecY (25%)" RLSDYMHFALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) YAGGMLDR root "1.4.1.13 (87.8%) 1.4.3.- (8%) 1.-.-.- (3.1%)" "glutamate synthase (NADPH) (87.8%) With oxygen as acceptor (8%) Oxidoreductases (3.1%)" "GO:0006537 (18.2%) GO:0019676 (18%) GO:0006529 (0.1%)" "GO:0005737 (4.6%) GO:0005643 (0.1%) GO:0005829 (0.1%)" "GO:0051538 (18.2%) GO:0046872 (18.1%) GO:0015930 (9.9%)" "glutamate biosynthetic process (18.2%) ammonia assimilation cycle (18%) obsolete asparagine biosynthetic process (0.1%)" "cytoplasm (4.6%) nuclear pore (0.1%) cytosol (0.1%)" "3 iron, 4 sulfur cluster binding (18.2%) metal ion binding (18.1%) glutamate synthase activity (9.9%)" "IPR017932 (11.9%) IPR006982 (11.8%) IPR029055 (11.8%)" "Glutamine amidotransferase type 2 domain (11.9%) Glutamate synthase, central-N (11.8%) Nucleophile aminohydrolases, N-terminal (11.8%)" KLTFQHLTEEGLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (25.8%) IPR012131 (25.8%) IPR016161 (24.2%)" "Histidinol dehydrogenase, conserved site (25.8%) Histidinol dehydrogenase (25.8%) Aldehyde/histidinol dehydrogenase (24.2%)" VLFGEYNPAGK Bacteria Bacteria "3.2.1.21 (75%) 3.2.1.37 (25%)" "beta-glucosidase (75%) xylan 1,4-beta-xylosidase (25%)" "GO:0031222 (23.9%) GO:0045493 (23.9%) GO:0005975 (1.1%)" "GO:0009044 (23.9%) GO:0046556 (23.9%) GO:0008422 (1.7%)" "arabinan catabolic process (23.9%) xylan catabolic process (23.9%) carbohydrate metabolic process (1.1%)" "xylan 1,4-beta-xylosidase activity (23.9%) alpha-L-arabinofuranosidase activity (23.9%) beta-glucosidase activity (1.7%)" "IPR002772 (9.6%) IPR026891 (9.6%) IPR001764 (9.2%)" "Glycoside hydrolase family 3 C-terminal domain (9.6%) Fibronectin type III-like domain (9.6%) Glycoside hydrolase, family 3, N-terminal (9.2%)" EFAGYHSQLAAAADPTEVVRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.4%) IPR000297 (25%) IPR046357 (25%)" "Periplasmic chaperone PpiD (26.4%) Peptidyl-prolyl cis-trans isomerase, PpiC-type (25%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25%)" YDDQFVTNYALLNVLPQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (24.1%) GO:0005886 (25.5%) "GO:0042910 (25.5%) GO:0015562 (24.8%)" response to toxic substance (24.1%) plasma membrane (25.5%) "xenobiotic transmembrane transporter activity (25.5%) efflux transmembrane transporter activity (24.8%)" "IPR001036 (34%) IPR004764 (33%) IPR027463 (33%)" "Acriflavin resistance protein (34%) Multidrug resistance protein MdtF-like (33%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33%)" AGTDMDMCSNAFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" NNLPAFQYLNLEQMPNNLLAGNFAQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0007234 (12.9%) GO:0000160 (12.1%)" GO:0016020 (24.2%) "GO:0016301 (25%) GO:0000156 (12.9%) GO:0030295 (12.9%)" "osmosensory signaling via phosphorelay pathway (12.9%) phosphorelay signal transduction system (12.1%)" membrane (24.2%) "kinase activity (25%) phosphorelay response regulator activity (12.9%) protein kinase activator activity (12.9%)" "IPR003594 (12.9%) IPR005467 (12.9%) IPR033405 (12.9%)" "Histidine kinase/HSP90-like ATPase domain (12.9%) Histidine kinase domain (12.9%) Domain of unknown function DUF5112 (12.9%)" KEGALYYLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VLTFPDEGSEGKELNGYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VLHLLGSPAYNSNGTLVLGTAEGGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR030890 (100%) Substrate import-associated zinc metallohydrolase lipoprotein (100%) PTSLSFEDVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" AFGLCLTPEGTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006654 (50%) GO:0003841 (50%) phosphatidic acid biosynthetic process (50%) 1-acylglycerol-3-phosphate O-acyltransferase activity (50%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) YNFDPYK root "GO:0016052 (26.9%) GO:0006284 (3.8%)" "GO:0004553 (26.9%) GO:0030246 (26.9%) GO:0016787 (7.7%)" "carbohydrate catabolic process (26.9%) base-excision repair (3.8%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (26.9%) carbohydrate binding (26.9%) hydrolase activity (7.7%)" "IPR045743 (40%) IPR011250 (37.8%) IPR045670 (11.1%)" "Domain of unknown function DUF6089 (40%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (37.8%) Domain of unknown function DUF5916 (11.1%)" AAFEAALTR Bacteria Bacteria "2.7.3.9 (33.3%) 1.8.4.11 (11.1%) 2.1.1.297 (11.1%)" "phosphoenolpyruvate--protein phosphotransferase (33.3%) peptide-methionine (S)-S-oxide reductase (11.1%) peptide chain release factor N(5)-glutamine methyltransferase (11.1%)" "GO:0000160 (1.4%) GO:0000162 (1.4%) GO:0006189 (1.4%)" "GO:0016020 (63.8%) GO:0005737 (2.9%) GO:0005829 (1.4%)" "GO:0046872 (4.3%) GO:0003677 (2.9%) GO:0003676 (1.4%)" "phosphorelay signal transduction system (1.4%) L-tryptophan biosynthetic process (1.4%) 'de novo' IMP biosynthetic process (1.4%)" "membrane (63.8%) cytoplasm (2.9%) cytosol (1.4%)" "metal ion binding (4.3%) DNA binding (2.9%) nucleic acid binding (1.4%)" "IPR003672 (38.1%) IPR009003 (2.7%) IPR000032 (1.8%)" "CobN/magnesium chelatase (38.1%) Peptidase S1, PA clan (2.7%) Phosphocarrier protein HPr-like (1.8%)" FNEHGTSSALVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.198 (100%) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (100%) GO:0005737 (50%) GO:0070677 (50%) cytoplasm (50%) rRNA (cytosine-2'-O-)-methyltransferase activity (50%) "IPR000878 (18.2%) IPR008189 (18.2%) IPR018063 (18.2%)" "Tetrapyrrole methylase (18.2%) rRNA small subunit methyltransferase I (18.2%) SAM-dependent methyltransferase RsmI, conserved site (18.2%)" GEHHYSQLELNHYLHAVTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.9%) IPR029483 (14.9%) IPR029486 (14.9%)" "Glycosyl-hydrolase 97, catalytic domain (14.9%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.9%) Glycosyl-hydrolase 97, N-terminal domain (14.9%)" AWNVPLDADLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR018392 (33.6%) IPR028082 (33.6%) IPR036779 (32.9%)" "LysM domain (33.6%) Periplasmic binding protein-like I (33.6%) LysM domain superfamily (32.9%)" RVLVPAESESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (18.7%) IPR002890 (18.7%) IPR008930 (18.7%)" "Alpha-2-macroglobulin (18.7%) Macroglobulin domain (18.7%) Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (18.7%)" FAAGLYYQAPFFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (28.8%) IPR008969 (27.3%) IPR037066 (27.3%)" "TonB-dependent receptor, plug domain (28.8%) Carboxypeptidase-like, regulatory domain superfamily (27.3%) TonB-dependent receptor, plug domain superfamily (27.3%)" LVLSDWK root "2.7.13.3 (61.5%) 2.7.7.7 (11.5%) 2.1.1.72 (7.7%)" "histidine kinase (61.5%) DNA-directed DNA polymerase (11.5%) site-specific DNA-methyltransferase (adenine-specific) (7.7%)" "GO:0000160 (3.7%) GO:0006508 (2.6%) GO:0006355 (1.9%)" "GO:0016020 (17.2%) GO:0005886 (9%) GO:0009279 (1.1%)" "GO:0005524 (8.2%) GO:0000155 (6%) GO:0008233 (2.6%)" "phosphorelay signal transduction system (3.7%) proteolysis (2.6%) regulation of DNA-templated transcription (1.9%)" "membrane (17.2%) plasma membrane (9%) cell outer membrane (1.1%)" "ATP binding (8.2%) phosphorelay sensor kinase activity (6%) peptidase activity (2.6%)" "IPR021280 (5.1%) IPR052724 (5.1%) IPR001789 (4.8%)" "Protein O-mannosyl-transferase TMEM260-like (5.1%) Glycosyltransferase 117 domain-containing protein (5.1%) Signal transduction response regulator, receiver domain (4.8%)" GDYMNFEYASLGYTFTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NGAELTLTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" NPFYYQLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (20.3%) GO:0009252 (20.3%) GO:0071555 (20.3%)" "GO:0016740 (20.3%) GO:0004180 (19%)" "regulation of cell shape (20.3%) peptidoglycan biosynthetic process (20.3%) cell wall organization (20.3%)" "transferase activity (20.3%) carboxypeptidase activity (19%)" "IPR005490 (25.4%) IPR045380 (25.4%) IPR052905 (25.4%)" "L,D-transpeptidase catalytic domain (25.4%) L,D-transpeptidase, scaffold domain (25.4%) L,D-transpeptidase YkuD-like (25.4%)" MKDVHAVLGGEGNGGVLYPESHYGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.4.2.10 (92.3%) 5.4.2.- (3.8%) 5.4.2.8 (3.8%)" "phosphoglucosamine mutase (92.3%) Phosphotransferases (phosphomutases) (3.8%) phosphomannomutase (3.8%)" "GO:0005975 (14.7%) GO:0006048 (14.1%) GO:0009252 (14.1%)" GO:0005829 (14.1%) "GO:0000287 (14.1%) GO:0004615 (14.1%) GO:0008966 (14.1%)" "carbohydrate metabolic process (14.7%) UDP-N-acetylglucosamine biosynthetic process (14.1%) peptidoglycan biosynthetic process (14.1%)" cytosol (14.1%) "magnesium ion binding (14.1%) phosphomannomutase activity (14.1%) phosphoglucosamine mutase activity (14.1%)" "IPR005846 (10.4%) IPR005843 (10%) IPR005844 (10%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (10.4%) Alpha-D-phosphohexomutase, C-terminal (10%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10%)" VWYDSPTLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005975 (10%) "GO:0016747 (60%) GO:0016787 (20%) GO:0004553 (10%)" carbohydrate metabolic process (10%) "acyltransferase activity, transferring groups other than amino-acyl groups (60%) hydrolase activity (20%) hydrolase activity, hydrolyzing O-glycosyl compounds (10%)" "IPR000801 (20.3%) IPR050583 (20.3%) IPR013783 (18.9%)" "Esterase-like (20.3%) Mycobacterial A85 antigen (20.3%) Immunoglobulin-like fold (18.9%)" ENLWNLAPYSCAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.9 (100%) histidinol-phosphate transaminase (100%) GO:0000105 (33.3%) "GO:0004400 (33.3%) GO:0030170 (33.3%)" L-histidine biosynthetic process (33.3%) "histidinol-phosphate transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR001917 (17%) IPR004839 (17%) IPR005861 (17%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (17%) Aminotransferase, class I/classII, large domain (17%) Histidinol-phosphate aminotransferase family (17%)" NYLSGFPQYFAGGWNVTNYAGSNFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR011990 (37.1%) IPR041662 (37.1%) IPR024302 (25.7%)" "Tetratricopeptide-like helical domain superfamily (37.1%) SusD-like 2 (37.1%) SusD-like (25.7%)" DDLFDYYDSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.5.1.90 (40%) 2.5.1.- (20%) 2.5.1.31 (20%)" "all-trans-octaprenyl-diphosphate synthase (40%) Transferring alkyl or aryl groups, other than methyl groups (20%) ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyldiphosphate specific] (20%)" GO:0008299 (50%) "GO:0004659 (45.2%) GO:0106350 (2.9%) GO:0008834 (1%)" isoprenoid biosynthetic process (50%) "prenyltransferase activity (45.2%) all-trans-octaprenyl-diphosphate synthase activity (2.9%) ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity (1%)" "IPR000092 (33.8%) IPR033749 (33.8%) IPR008949 (32.5%)" "Polyprenyl synthetase-like (33.8%) Polyprenyl synthetase, conserved site (33.8%) Isoprenoid synthase domain superfamily (32.5%)" TGAAMSLNAQQLADMPSLSHSLADVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" FMVESVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.6%) "GO:0003677 (25.6%) GO:0003917 (25.6%) GO:0046872 (23.2%)" DNA topological change (25.6%) "DNA binding (25.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.6%) metal ion binding (23.2%)" "IPR000380 (7.5%) IPR003601 (7.5%) IPR006171 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, domain 2 (7.5%) TOPRIM domain (7.5%)" LLLLVNQLLDFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (2.1%) "GO:0000155 (24.5%) GO:0003700 (24.5%) GO:0005524 (24.5%)" membrane (2.1%) "phosphorelay sensor kinase activity (24.5%) DNA-binding transcription factor activity (24.5%) ATP binding (24.5%)" "IPR001789 (6.9%) IPR003594 (6.9%) IPR003661 (6.9%)" "Signal transduction response regulator, receiver domain (6.9%) Histidine kinase/HSP90-like ATPase domain (6.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.9%)" ACESGDLLK Pseudomonadati Bacteria Pseudomonadati 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (19.3%) GO:0006096 (19.3%)" "GO:0005829 (19.3%) GO:0042597 (1.1%)" "GO:0004619 (19.3%) GO:0030145 (19.3%) GO:0003677 (1.1%)" "glucose catabolic process (19.3%) glycolytic process (19.3%)" "cytosol (19.3%) periplasmic space (1.1%)" "phosphoglycerate mutase activity (19.3%) manganese ion binding (19.3%) DNA binding (1.1%)" "IPR005995 (18.5%) IPR006124 (18.5%) IPR011258 (18.5%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (18.5%) Metalloenzyme (18.5%) BPG-independent PGAM, N-terminal (18.5%)" DTLLAMNLFNSVFVDCTASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.1.1.3 (50.7%) 2.7.2.4 (49.3%)" "homoserine dehydrogenase (50.7%) aspartate kinase (49.3%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" FSFGQQGNDALGNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR036942 (13.3%) IPR039426 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.3%) TonB-dependent receptor-like (13.3%)" LDVFDFVTPYPDFDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.9%) GO:0016787 (48.1%)" "carbohydrate binding (51.9%) hydrolase activity (48.1%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" EYQYLNNYEPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (38.2%) GO:0000272 (11.8%)" "GO:0004553 (41.2%) GO:0031176 (8.8%)" "xylan catabolic process (38.2%) polysaccharide catabolic process (11.8%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (41.2%) endo-1,4-beta-xylanase activity (8.8%)" "IPR001000 (28.3%) IPR017853 (26.7%) IPR044846 (26.7%)" "Glycoside hydrolase family 10 domain (28.3%) Glycoside hydrolase superfamily (26.7%) Glycoside hydrolase family 10 (26.7%)" FQAQAVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.2%) IPR003156 (9.2%) IPR012947 (9.2%)" "Alanine-tRNA ligase, class IIc (9.2%) DHHA1 domain (9.2%) Threonyl/alanyl tRNA synthetase, SAD (9.2%)" LLQALQSNLYNYEQSFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021857 (100%) Protein of unknown function DUF3467 (100%) VLDSGKYDLVPGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35%) IPR033985 (35%) IPR012944 (30%)" "Tetratricopeptide-like helical domain superfamily (35%) SusD-like, N-terminal (35%) RagB/SusD domain (30%)" VLMKDGEELPTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.6.5.9 (100%) NADH:ubiquinone reductase (non-electrogenic) (100%) GO:0003954 (100%) NADH dehydrogenase activity (100%) "IPR023753 (25%) IPR036188 (25%) IPR045024 (25%)" "FAD/NAD(P)-binding domain (25%) FAD/NAD(P)-binding domain superfamily (25%) Alternative NADH dehydrogenase (25%)" GLVYSDDFSKDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" MNDEESLKLSDELATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (20%) GO:0005886 (20%) "GO:0003723 (20%) GO:0004521 (20%) GO:0016787 (20%)" mRNA catabolic process (20%) plasma membrane (20%) "RNA binding (20%) RNA endonuclease activity (20%) hydrolase activity (20%)" "IPR003607 (12.7%) IPR004087 (12.7%) IPR004088 (12.7%)" "HD/PDEase domain (12.7%) K Homology domain (12.7%) K Homology domain, type 1 (12.7%)" NQMLHSASENSPTVTPLSAQLDDLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (16.7%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (16.7%)" "IPR003856 (16.7%) IPR005702 (16.7%) IPR025669 (16.7%)" "Polysaccharide chain length determinant, N-terminal domain (16.7%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.7%) AAA domain (16.7%)" ATGTDDAAAVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025970 (33.3%) IPR033404 (33.3%) IPR033407 (33.3%)" "SusE outer membrane protein (33.3%) Domain of unknown function DUF5111 (33.3%) Domain of unknown function DUF5114 (33.3%)" KLFPNGGGSLFTFDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (16.7%) IPR006235 (16.7%) IPR015421 (16.7%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (16.7%) O-acetylhomoserine/O-acetylserine sulfhydrylase (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" LTDAAGSNSAYFSGDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" SGLSQVEAELFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005829 (25.2%) GO:0016020 (24.3%)" "GO:0003677 (25.2%) GO:0030527 (25.2%)" "cytosol (25.2%) membrane (24.3%)" "DNA binding (25.2%) structural constituent of chromatin (25.2%)" "IPR000119 (50.9%) IPR010992 (47.4%) IPR036779 (1.8%)" "Histone-like DNA-binding protein (50.9%) Integration host factor (IHF)-like DNA-binding domain superfamily (47.4%) LysM domain superfamily (1.8%)" LCVYELATGKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (75%) 3.4.14.12 (25%)" "Acting on peptide bonds (peptidases) (75%) Xaa-Xaa-Pro tripeptidyl-peptidase (25%)" GO:0006508 (49.4%) "GO:0004252 (49.4%) GO:0004177 (1.1%)" proteolysis (49.4%) "serine-type endopeptidase activity (49.4%) aminopeptidase activity (1.1%)" "IPR011659 (22.2%) IPR001375 (21.7%) IPR011042 (20.7%)" "WD40-like beta-propeller (22.2%) Peptidase S9, prolyl oligopeptidase, catalytic domain (21.7%) Six-bladed beta-propeller, TolB-like (20.7%)" AHLQLELVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (24.5%) GO:0005737 (25.2%) "GO:0046872 (25.2%) GO:0070006 (25.2%)" proteolysis (24.5%) cytoplasm (25.2%) "metal ion binding (25.2%) metalloaminopeptidase activity (25.2%)" "IPR000994 (13.1%) IPR050422 (13.1%) IPR000587 (12.5%)" "Peptidase M24 (13.1%) Xaa-Pro aminopeptidase P (13.1%) Creatinase, N-terminal (12.5%)" LKQEAYVCYETQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.6.4.- (50%) 3.6.4.13 (50%)" "Acting on ATP; involved in cellular and subcellular movement (50%) RNA helicase (50%)" GO:0005829 (20%) "GO:0003676 (20%) GO:0003724 (20%) GO:0005524 (20%)" cytosol (20%) "nucleic acid binding (20%) RNA helicase activity (20%) ATP binding (20%)" "IPR001650 (14.5%) IPR011545 (14.5%) IPR014001 (14.5%)" "Helicase, C-terminal domain-like (14.5%) DEAD/DEAH-box helicase domain (14.5%) Helicase superfamily 1/2, ATP-binding domain (14.5%)" DRLVALNR root "3.1.1.4 (31.6%) 2.7.13.3 (15.8%) 3.1.-.- (15.8%)" "phospholipase A2 (31.6%) histidine kinase (15.8%) Acting on ester bonds (15.8%)" "GO:0006412 (16.1%) GO:0042254 (15.8%) GO:0046475 (0.2%)" "GO:0015935 (16.1%) GO:0005737 (15.9%) GO:0005886 (0.5%)" "GO:0003735 (16.1%) GO:0019843 (16.1%) GO:0005524 (0.5%)" "translation (16.1%) ribosome biogenesis (15.8%) glycerophospholipid catabolic process (0.2%)" "small ribosomal subunit (16.1%) cytoplasm (15.9%) plasma membrane (0.5%)" "structural constituent of ribosome (16.1%) rRNA binding (16.1%) ATP binding (0.5%)" "IPR000851 (13.6%) IPR013810 (13.6%) IPR005324 (13.6%)" "Small ribosomal subunit protein uS5 (13.6%) Small ribosomal subunit protein uS5, N-terminal (13.6%) Small ribosomal subunit protein uS5, C-terminal (13.6%)" ADHFVVSPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32%) IPR033985 (32%) IPR012944 (29.3%)" "Tetratricopeptide-like helical domain superfamily (32%) SusD-like, N-terminal (32%) RagB/SusD domain (29.3%)" HEENMLEFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25.2%) GO:0005829 (25.2%) "GO:0070573 (25.2%) GO:0046872 (24.4%)" proteolysis (25.2%) cytosol (25.2%) "metallodipeptidase activity (25.2%) metal ion binding (24.4%)" "IPR001160 (36.2%) IPR002933 (35.1%) IPR011650 (28.7%)" "Peptidase M20C, Xaa-His dipeptidase (36.2%) Peptidase M20 (35.1%) Peptidase M20, dimerisation domain (28.7%)" ESYGYAAGWSVGNMGLGRPLPEDGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (16.7%) IPR008999 (16.7%) IPR013320 (16.7%)" "Glycoside hydrolase, family 43 (16.7%) Actin-crosslinking (16.7%) Concanavalin A-like lectin/glucanase domain superfamily (16.7%)" NLLTTTDQLEMLLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (28.3%) IPR033985 (28.3%) IPR012944 (21.7%)" "Tetratricopeptide-like helical domain superfamily (28.3%) SusD-like, N-terminal (28.3%) RagB/SusD domain (21.7%)" SANDHFNLANFMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (25%) IPR018485 (25%) IPR043129 (25%)" "Carbohydrate kinase FGGY, N-terminal (25%) Carbohydrate kinase FGGY, C-terminal (25%) ATPase, nucleotide binding domain (25%)" VNPTVYALEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.4.-.- (41.2%) 2.4.1.250 (41.2%) 2.4.1.284 (17.6%)" "Glycosyltransferases (41.2%) D-inositol-3-phosphate glycosyltransferase (41.2%) 2-deoxystreptamine glucosyltransferase (17.6%)" GO:0009103 (1.1%) "GO:0016757 (70.7%) GO:0016758 (17.4%) GO:0102710 (7.6%)" lipopolysaccharide biosynthetic process (1.1%) "glycosyltransferase activity (70.7%) hexosyltransferase activity (17.4%) D-inositol-3-phosphate glycosyltransferase activity (7.6%)" "IPR001296 (34.2%) IPR028098 (34.2%) IPR050194 (31.6%)" "Glycosyl transferase, family 1 (34.2%) Glycosyltransferase subfamily 4-like, N-terminal domain (34.2%) Glycosyltransferase group 1 (31.6%)" SSLWELQENDVFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SVTEAGLDYTGYPNPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TGNFLAMLLQVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NAFTPLTTWEMAQAFNYCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.3.36 (100%) 1,4-dihydroxy-2-naphthoyl-CoA synthase (100%) GO:0009234 (33.3%) GO:0005829 (33.3%) GO:0008935 (33.3%) menaquinone biosynthetic process (33.3%) cytosol (33.3%) 1,4-dihydroxy-2-naphthoyl-CoA synthase activity (33.3%) "IPR001753 (20%) IPR010198 (20%) IPR014748 (20%)" "Enoyl-CoA hydratase/isomerase (20%) 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB (20%) Enoyl-CoA hydratase, C-terminal (20%)" LAAYNQGLYGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" ASYDTLTSDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) TEKPEHTTLTLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.6%) IPR035994 (47.4%)" "Nucleoside phosphorylase domain (52.6%) Nucleoside phosphorylase superfamily (47.4%)" TTFNDEGYDTDWLDALSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" KQLGEQLTQPLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (25.5%) IPR017932 (25.5%) IPR029055 (24.5%)" "Phosphoribosyltransferase domain (25.5%) Glutamine amidotransferase type 2 domain (25.5%) Nucleophile aminohydrolases, N-terminal (24.5%)" QTDLLVSAAK root 2.5.1.55 (100%) 3-deoxy-8-phosphooctulonate synthase (100%) "GO:0009103 (14.4%) GO:0019294 (4%)" GO:0005737 (40.8%) GO:0008676 (40.8%) "lipopolysaccharide biosynthetic process (14.4%) keto-3-deoxy-D-manno-octulosonic acid biosynthetic process (4%)" cytoplasm (40.8%) 3-deoxy-8-phosphooctulonate synthase activity (40.8%) "IPR006218 (33.3%) IPR006269 (33.3%) IPR013785 (33.3%)" "DAHP synthetase I/KDSA (33.3%) 3-deoxy-8-phosphooctulonate synthase (33.3%) Aldolase-type TIM barrel (33.3%)" EPTNGGDLNALSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (60%) IPR008160 (40%)" "Domain of unknown function DUF4988 (60%) Collagen triple helix repeat (40%)" VLVASELK root "6.3.5.4 (79.1%) 5.4.99.62 (9.3%) 2.7.7.49 (4.7%)" "asparagine synthase (glutamine-hydrolyzing) (79.1%) D-ribose pyranase (9.3%) RNA-directed DNA polymerase (4.7%)" "GO:0006529 (15.6%) GO:0000160 (2.8%) GO:0006355 (2.8%)" "GO:0005829 (17.1%) GO:0016020 (2.4%) GO:0000813 (0.5%)" "GO:0004066 (15.6%) GO:0005524 (15.2%) GO:0003677 (2.8%)" "obsolete asparagine biosynthetic process (15.6%) phosphorelay signal transduction system (2.8%) regulation of DNA-templated transcription (2.8%)" "cytosol (17.1%) membrane (2.4%) ESCRT I complex (0.5%)" "asparagine synthase (glutamine-hydrolyzing) activity (15.6%) ATP binding (15.2%) DNA binding (2.8%)" "IPR017932 (9.8%) IPR050795 (9.8%) IPR001962 (9.5%)" "Glutamine amidotransferase type 2 domain (9.8%) Asparagine Synthetase (9.8%) Asparagine synthase (9.5%)" GETAYFEYLYFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" KHGAASTLFGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR032816 (50%) IPR051311 (50%)" "VTT domain (50%) DedA domain-containing protein (50%)" MPGTDQMSLLLQGLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.5%) GO:0034605 (12.5%)" GO:0005737 (12.5%) "GO:0004176 (12.5%) GO:0004252 (12.5%) GO:0005524 (12.5%)" "protein quality control for misfolded or incompletely synthesized proteins (12.5%) cellular response to heat (12.5%)" cytoplasm (12.5%) "ATP-dependent peptidase activity (12.5%) serine-type endopeptidase activity (12.5%) ATP binding (12.5%)" "IPR003111 (7.1%) IPR003593 (7.1%) IPR003959 (7.1%)" "Lon protease, N-terminal domain (7.1%) AAA+ ATPase domain (7.1%) ATPase, AAA-type, core (7.1%)" TEFVNSVDEVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.1.30.- (96.9%) 3.-.-.- (3.1%)" "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (96.9%) Hydrolases (3.1%)" "GO:0003676 (25%) GO:0004519 (25%) GO:0016787 (25%)" "nucleic acid binding (25%) endonuclease activity (25%) hydrolase activity (25%)" "IPR001604 (16.8%) IPR018524 (16.8%) IPR020821 (16.8%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (16.8%) DNA/RNA non-specific endonuclease, active site (16.8%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (16.8%)" DGLEVDYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" QLGNVEVPQK Bacteria Bacteria "3.6.5.0 (94.3%) 3.6.5.- (5.7%)" "Unknown (94.3%) Acting on GTP; involved in cellular and subcellular movement (5.7%)" GO:0045727 (16.9%) GO:0005886 (15.6%) "GO:0005525 (16.9%) GO:0043022 (16.9%) GO:0003746 (16.8%)" positive regulation of translation (16.9%) plasma membrane (15.6%) "GTP binding (16.9%) ribosome binding (16.9%) translation elongation factor activity (16.8%)" "IPR006297 (9.8%) IPR013842 (9.8%) IPR000640 (9.8%)" "Elongation factor 4 (9.8%) GTP-binding protein LepA, C-terminal (9.8%) Elongation factor EFG, domain V-like (9.8%)" WNDFDQDLFDTLYNDDSQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.7%) IPR002052 (16.7%) IPR004114 (16.7%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.7%) DNA methylase, N-6 adenine-specific, conserved site (16.7%) THUMP domain (16.7%)" SYGDGLGDQVTSAYTNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (20%) IPR036942 (20%) IPR037066 (20%)" "Carboxypeptidase-like, regulatory domain superfamily (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%) TonB-dependent receptor, plug domain superfamily (20%)" TNLLANLANMYYTLLMLDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" HDGDLANYMSTNVFLTGDGDYSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri HALVGVLEEAMGLELSDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (52.9%) 1.6.5.9 (35.3%) 1.6.5.3 (11.8%)" "Transferred entry: 1.6.5.9 (52.9%) NADH:ubiquinone reductase (non-electrogenic) (35.3%) Transferred entry: 7.1.1.2 (11.8%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (19.8%) IPR001268 (19.8%) IPR022885 (19.8%)" "NADH-quinone oxidoreductase, subunit D (19.8%) NADH:ubiquinone oxidoreductase, 30kDa subunit (19.8%) NAD(P)H-quinone oxidoreductase subunit D/H (19.8%)" DTDKPTVVHLHTEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.7 (100%) 1-deoxy-D-xylulose-5-phosphate synthase (100%) "GO:0016114 (16.2%) GO:0019288 (16.2%) GO:0009228 (15.1%)" GO:0005829 (16.2%) "GO:0008661 (16.2%) GO:0046872 (15.1%)" "terpenoid biosynthetic process (16.2%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (16.2%) thiamine biosynthetic process (15.1%)" cytosol (16.2%) "1-deoxy-D-xylulose-5-phosphate synthase activity (16.2%) metal ion binding (15.1%)" "IPR005475 (17.1%) IPR005477 (17.1%) IPR033248 (17.1%)" "Transketolase-like, pyrimidine-binding domain (17.1%) Deoxyxylulose-5-phosphate synthase (17.1%) Transketolase, C-terminal domain (17.1%)" AQQVEFNLDGAAAPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (27.1%) IPR013780 (24.7%) IPR017853 (24.7%)" "Alpha-L-arabinofuranosidase, C-terminal (27.1%) Glycosyl hydrolase, all-beta (24.7%) Glycoside hydrolase superfamily (24.7%)" SLLQAFLEPLDTLRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.7%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.7%)" VGNHLLYLGNLPETNLLDKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (100%) cell division (100%) ELEDEGLSDVEMDDMGYLYATLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.4 (100%) tripeptide aminopeptidase (100%) "GO:0006508 (16.3%) GO:0043171 (16.3%)" GO:0005829 (17.4%) "GO:0045148 (17.4%) GO:0008237 (16.3%) GO:0008270 (16.3%)" "proteolysis (16.3%) peptide catabolic process (16.3%)" cytosol (17.4%) "tripeptide aminopeptidase activity (17.4%) metallopeptidase activity (16.3%) zinc ion binding (16.3%)" "IPR001261 (20.5%) IPR002933 (20.5%) IPR010161 (20.5%)" "ArgE/DapE/ACY1/CPG2/YscS, conserved site (20.5%) Peptidase M20 (20.5%) Peptidase M20B, tripeptide aminopeptidase (20.5%)" ALGDWLLGMNATR Bacteroidota Bacteria Pseudomonadati Bacteroidota "5.6.2.1 (99.4%) 5.6.2.2 (0.4%) 5.99.1.2 (0.1%)" "DNA topoisomerase (99.4%) DNA topoisomerase (ATP-hydrolyzing) (0.4%) Transferred entry: 5.6.2.1 (0.1%)" "GO:0006265 (16.7%) GO:0006281 (16.7%) GO:0006310 (16.7%)" GO:0043597 (16.7%) "GO:0003677 (16.7%) GO:0003917 (16.7%) GO:0003918 (0.1%)" "DNA topological change (16.7%) DNA repair (16.7%) DNA recombination (16.7%)" cytoplasmic replication fork (16.7%) "DNA binding (16.7%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (0.1%)" "IPR000380 (9%) IPR003601 (9%) IPR013497 (9%)" "DNA topoisomerase, type IA (9%) DNA topoisomerase, type IA, domain 2 (9%) DNA topoisomerase, type IA, central (9%)" MPALEGLLYLPDYSLVVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25%) IPR020845 (25%) IPR042099 (25%)" "AMP-dependent synthetase/ligase domain (25%) AMP-binding, conserved site (25%) ANL, N-terminal domain (25%)" QLDTLAAEYPAQTNYLYVTYAGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.1%) GO:0006221 (12.9%) GO:0006526 (12.9%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (12.9%) L-arginine biosynthetic process (12.9%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005480 (10.7%) IPR005479 (10.3%) IPR011761 (10.3%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.7%) Carbamoyl phosphate synthase, ATP-binding domain (10.3%) ATP-grasp fold (10.3%)" ETLEDVNFLVFCGGFSNSDVLGSAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.8%) GO:0006164 (0.3%)" GO:0005737 (20.1%) "GO:0004642 (20.1%) GO:0005524 (19.8%) GO:0046872 (19.8%)" "'de novo' IMP biosynthetic process (19.8%) purine nucleotide biosynthetic process (0.3%)" cytoplasm (20.1%) "phosphoribosylformylglycinamidine synthase activity (20.1%) ATP binding (19.8%) metal ion binding (19.8%)" "IPR010073 (11.2%) IPR010918 (11.2%) IPR040707 (11.2%)" "Phosphoribosylformylglycinamidine synthase PurL (11.2%) PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.2%)" VDFTAADDPHAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" ALYDGFGNSSNNKPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.7.8.- (94.1%) 3.1.-.- (5.9%)" "Transferases for other substituted phosphate groups (94.1%) Acting on ester bonds (5.9%)" GO:0032049 (36.9%) GO:0005886 (24.6%) "GO:0008808 (24.6%) GO:0030572 (12.3%) GO:0016787 (1.5%)" cardiolipin biosynthetic process (36.9%) plasma membrane (24.6%) "cardiolipin synthase activity (24.6%) phosphatidyltransferase activity (12.3%) hydrolase activity (1.5%)" "IPR001736 (37.5%) IPR025202 (37.5%) IPR022924 (25%)" "Phospholipase D/Transphosphatidylase (37.5%) Phospholipase D-like domain (37.5%) Cardiolipin synthase (25%)" PGYLNFLDAFNSWQLVK Bacteria Bacteria "2.1.2.3 (95.8%) 3.5.4.10 (4.2%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (95.8%) IMP cyclohydrolase (4.2%)" GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (25.2%) IPR016193 (25%) IPR024051 (25%)" "Bifunctional purine biosynthesis protein PurH-like (25.2%) Cytidine deaminase-like (25%) AICAR transformylase, duplicated domain superfamily (25%)" LSATGDYELDELRA Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006139 (33.3%) "GO:0003676 (33.3%) GO:0008408 (33.3%)" nucleobase-containing compound metabolic process (33.3%) "nucleic acid binding (33.3%) 3'-5' exonuclease activity (33.3%)" "IPR002562 (25%) IPR012337 (25%) IPR036397 (25%)" "3'-5' exonuclease domain (25%) Ribonuclease H-like superfamily (25%) Ribonuclease H superfamily (25%)" LCPLESPEGPNLGLLSSLCMYAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007645 (8.9%) IPR015712 (8.9%) IPR019462 (8.9%)" "RNA polymerase Rpb2, domain 3 (8.9%) DNA-directed RNA polymerase, subunit 2 (8.9%) DNA-directed RNA polymerase, beta subunit, external 1 domain (8.9%)" LAGDLTALR root "2.7.1.5 (50%) 4.1.99.17 (50%)" "rhamnulokinase (50%) phosphomethylpyrimidine synthase (50%)" "GO:0006281 (16.3%) GO:0006310 (16.3%) GO:0009432 (16.3%)" "GO:0043590 (16.3%) GO:0016020 (3.1%) GO:0005829 (1%)" "GO:0005524 (16.3%) GO:0008270 (3.1%) GO:0008168 (1%)" "DNA repair (16.3%) DNA recombination (16.3%) SOS response (16.3%)" "bacterial nucleoid (16.3%) membrane (3.1%) cytosol (1%)" "ATP binding (16.3%) zinc ion binding (3.1%) methyltransferase activity (1%)" "IPR003395 (21.3%) IPR004604 (21.3%) IPR027417 (21.3%)" "RecF/RecN/SMC, N-terminal (21.3%) DNA recombination/repair protein RecN (21.3%) P-loop containing nucleoside triphosphate hydrolase (21.3%)" VGDVLFNTQQLEEQLALAEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.1 (100%) NAD(+) synthase (glutamine-hydrolyzing) (100%) GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (15%) IPR003694 (15%) IPR014445 (15%)" "Carbon-nitrogen hydrolase (15%) NAD(+) synthetase (15%) Glutamine-dependent NAD(+) synthetase (15%)" YLSLLSK root "6.3.2.2 (29.5%) 3.6.4.13 (17.3%) 2.7.13.3 (7.9%)" "glutamate--cysteine ligase (29.5%) RNA helicase (17.3%) histidine kinase (7.9%)" "GO:0006750 (2.8%) GO:0000390 (1.2%) GO:0016042 (0.9%)" "GO:0016020 (5.8%) GO:0017109 (2.7%) GO:0005634 (2.3%)" "GO:0005524 (6.3%) GO:0004357 (2.8%) GO:0003723 (2.3%)" "glutathione biosynthetic process (2.8%) spliceosomal complex disassembly (1.2%) lipid catabolic process (0.9%)" "membrane (5.8%) glutamate-cysteine ligase complex (2.7%) nucleus (2.3%)" "ATP binding (6.3%) glutamate-cysteine ligase activity (2.8%) RNA binding (2.3%)" "IPR027417 (3.2%) IPR004308 (2.1%) IPR014746 (2%)" "P-loop containing nucleoside triphosphate hydrolase (3.2%) Glutamate-cysteine ligase catalytic subunit (2.1%) Glutamine synthetase/guanido kinase, catalytic domain (2%)" LSLNPGYNPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006298 (14.7%) GO:0032300 (14.2%) "GO:0005524 (14.7%) GO:0016887 (14.2%) GO:0030983 (14.2%)" mismatch repair (14.7%) mismatch repair complex (14.2%) "ATP binding (14.7%) ATP hydrolysis activity (14.2%) mismatched DNA binding (14.2%)" "IPR014790 (8.7%) IPR002099 (8.4%) IPR013507 (8.4%)" "MutL, C-terminal, dimerisation (8.7%) DNA mismatch repair protein MutL/Mlh/PMS (8.4%) DNA mismatch repair protein, S5 domain 2-like (8.4%)" YQVYDLK root 3.2.1.40 (100%) alpha-L-rhamnosidase (100%) "GO:0005987 (19.6%) GO:0005975 (2.2%) GO:0015074 (2.2%)" "GO:0005737 (20.3%) GO:0016020 (5.1%) GO:0005634 (2.2%)" "GO:0004575 (19.6%) GO:0003723 (2.2%) GO:0030596 (2.2%)" "sucrose catabolic process (19.6%) carbohydrate metabolic process (2.2%) DNA integration (2.2%)" "cytoplasm (20.3%) membrane (5.1%) nucleus (2.2%)" "sucrose alpha-glucosidase activity (19.6%) RNA binding (2.2%) alpha-L-rhamnosidase activity (2.2%)" "IPR001362 (9.5%) IPR013148 (9.5%) IPR013189 (9.5%)" "Glycoside hydrolase, family 32 (9.5%) Glycosyl hydrolase family 32, N-terminal (9.5%) Glycosyl hydrolase family 32, C-terminal (9.5%)" YWLDEYHLDGFR Pseudomonadati Bacteria Pseudomonadati "3.2.1.41 (97.7%) 3.2.1.141 (2.3%)" "pullulanase (97.7%) 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (2.3%)" "GO:0005975 (48.3%) GO:0005978 (1.1%)" "GO:0016798 (31%) GO:0051060 (17.2%) GO:0003844 (1.1%)" "carbohydrate metabolic process (48.3%) glycogen biosynthetic process (1.1%)" "hydrolase activity, acting on glycosyl bonds (31%) pullulanase activity (17.2%) 1,4-alpha-glucan branching enzyme activity (1.1%)" "IPR006047 (15.2%) IPR011840 (14.5%) IPR049117 (14.5%)" "Glycosyl hydrolase family 13, catalytic domain (15.2%) Pullulanase, type I (14.5%) Pullulanase, all-beta domain (14.5%)" LVAQLMR root "3.5.1.16 (25.6%) 3.6.4.13 (24%) 2.5.1.49 (9.3%)" "acetylornithine deacetylase (25.6%) RNA helicase (24%) O-acetylhomoserine aminocarboxypropyltransferase (9.3%)" "GO:0006535 (3.8%) GO:0019346 (3.8%) GO:0071269 (3.8%)" "GO:0005737 (6.6%) GO:0005886 (4.4%) GO:0009380 (2.6%)" "GO:0005524 (5.3%) GO:0016787 (4%) GO:0030170 (4%)" "cysteine biosynthetic process from serine (3.8%) transsulfuration (3.8%) L-homocysteine biosynthetic process (3.8%)" "cytoplasm (6.6%) plasma membrane (4.4%) excinuclease repair complex (2.6%)" "ATP binding (5.3%) hydrolase activity (4%) pyridoxal phosphate binding (4%)" "IPR027417 (4.8%) IPR015421 (3.7%) IPR015422 (3.7%)" "P-loop containing nucleoside triphosphate hydrolase (4.8%) Pyridoxal phosphate-dependent transferase, major domain (3.7%) Pyridoxal phosphate-dependent transferase, small domain (3.7%)" SLLTELMHTYSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LFNLSDVVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QYPDLLKALGENR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009244 (33.3%) GO:0005886 (33.3%) GO:0016776 (33.3%) lipopolysaccharide core region biosynthetic process (33.3%) plasma membrane (33.3%) phosphotransferase activity, phosphate group as acceptor (33.3%) "IPR000917 (25.5%) IPR012549 (25.5%) IPR040423 (25.5%)" "Sulfatase, N-terminal (25.5%) Phosphoethanolamine transferase, N-terminal (25.5%) Phosphoethanolamine transferase (25.5%)" PFLSDLR root "3.1.13.- (87.8%) 5.6.2.3 (4.2%) 4.3.1.18 (1.6%)" "Exoribonucleases producing 5'-phosphomonoesters (87.8%) DNA 5'-3' helicase (4.2%) D-serine ammonia-lyase (1.6%)" "GO:0000956 (11%) GO:0016075 (10.8%) GO:0071044 (1.3%)" "GO:0005634 (11.2%) GO:0005737 (10.6%) GO:0005829 (1.7%)" "GO:0004534 (12.2%) GO:0003723 (11.1%) GO:0003677 (6.7%)" "nuclear-transcribed mRNA catabolic process (11%) rRNA catabolic process (10.8%) histone mRNA catabolic process (1.3%)" "nucleus (11.2%) cytoplasm (10.6%) cytosol (1.7%)" "5'-3' RNA exonuclease activity (12.2%) RNA binding (11.1%) DNA binding (6.7%)" "IPR027073 (9.1%) IPR041412 (9.1%) IPR004859 (8.7%)" "5'-3' exoribonuclease (9.1%) Xrn1, helical domain (9.1%) Xrn1, N-terminal (8.7%)" LELLEVDEEDTSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (49.1%) GO:0016887 (49.1%) GO:0016740 (1.8%)" "ATP binding (49.1%) ATP hydrolysis activity (49.1%) transferase activity (1.8%)" "IPR003439 (16.8%) IPR003593 (16.8%) IPR017871 (16.8%)" "ABC transporter-like, ATP-binding domain (16.8%) AAA+ ATPase domain (16.8%) ABC transporter-like, conserved site (16.8%)" QTLGLGGLATLNTTDHLYDFTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" WGYFPSLAGAWTVSNEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (25%) GO:0009279 (75%) iron ion transport (25%) cell outer membrane (75%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" DFNAFELR root 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006261 (24.8%) "GO:0009360 (24.8%) GO:0005576 (0.3%) GO:0005737 (0.3%)" "GO:0003677 (24.8%) GO:0003887 (24.8%)" DNA-templated DNA replication (24.8%) "DNA polymerase III complex (24.8%) extracellular region (0.3%) cytoplasm (0.3%)" "DNA binding (24.8%) DNA-directed DNA polymerase activity (24.8%)" "IPR005790 (28.4%) IPR010372 (28.4%) IPR027417 (28%)" "DNA polymerase III, delta subunit (28.4%) DNA polymerase III delta, N-terminal (28.4%) P-loop containing nucleoside triphosphate hydrolase (28%)" MGGVLSLSPMVDVCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0009251 (46.6%) GO:0005975 (3.4%)" "GO:0008422 (46.6%) GO:0004553 (3.4%)" "glucan catabolic process (46.6%) carbohydrate metabolic process (3.4%)" "beta-glucosidase activity (46.6%) hydrolase activity, hydrolyzing O-glycosyl compounds (3.4%)" "IPR001764 (12.9%) IPR002772 (12.9%) IPR026891 (12.9%)" "Glycoside hydrolase, family 3, N-terminal (12.9%) Glycoside hydrolase family 3 C-terminal domain (12.9%) Fibronectin type III-like domain (12.9%)" MPHELSGGEQQR Bacteria Bacteria "7.6.2.9 (55.6%) 3.6.3.- (11.1%) 3.6.3.25 (11.1%)" "ABC-type quaternary amine transporter (55.6%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (11.1%) Transferred entry: 7.3.2.3 (11.1%)" "GO:0051301 (13.2%) GO:0015697 (0.2%) GO:0006865 (0.1%)" "GO:0005886 (21.4%) GO:0043190 (0.1%) GO:0005840 (0%)" "GO:0005524 (21.9%) GO:0016887 (21.8%) GO:0022857 (21.2%)" "cell division (13.2%) quaternary ammonium group transport (0.2%) amino acid transport (0.1%)" "plasma membrane (21.4%) ATP-binding cassette (ABC) transporter complex (0.1%) ribosome (0%)" "ATP binding (21.9%) ATP hydrolysis activity (21.8%) transmembrane transporter activity (21.2%)" "IPR003439 (18.1%) IPR003593 (18%) IPR017871 (18%)" "ABC transporter-like, ATP-binding domain (18.1%) AAA+ ATPase domain (18%) ABC transporter-like, conserved site (18%)" LAPADLSYNWLNYDFSVAATYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (93.3%) GO:0015344 (6.7%) cell outer membrane (93.3%) siderophore uptake transmembrane transporter activity (6.7%) "IPR036942 (93.3%) IPR039426 (6.7%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (93.3%) TonB-dependent receptor-like (6.7%)" LMELLYR root "2.8.1.6 (29.6%) 2.7.11.1 (13%) 3.4.22.61 (13%)" "biotin synthase (29.6%) non-specific serine/threonine protein kinase (13%) caspase-8 (13%)" "GO:0002758 (3.4%) GO:0009626 (3.4%) GO:0042742 (3.4%)" "GO:0016020 (3%) GO:0005700 (2.3%) GO:0098687 (2.3%)" "GO:0008270 (4.8%) GO:0043531 (3.7%) GO:0003677 (2.4%)" "innate immune response-activating signaling pathway (3.4%) plant-type hypersensitive response (3.4%) defense response to bacterium (3.4%)" "membrane (3%) polytene chromosome (2.3%) chromosomal region (2.3%)" "zinc ion binding (4.8%) ADP binding (3.7%) DNA binding (2.4%)" "IPR027417 (3.6%) IPR036388 (2.7%) IPR002182 (2.6%)" "P-loop containing nucleoside triphosphate hydrolase (3.6%) Winged helix-like DNA-binding domain superfamily (2.7%) NB-ARC (2.6%)" DNVNWADEVLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" GVELNLAGDVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR036942 (13.3%) IPR039426 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.3%) TonB-dependent receptor-like (13.3%)" AAGYVFLSPETYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (24.4%) GO:0030313 (22%) "GO:0016209 (26.8%) GO:0016491 (26.8%)" cytochrome complex assembly (24.4%) cell envelope (22%) "antioxidant activity (26.8%) oxidoreductase activity (26.8%)" "IPR000866 (20.4%) IPR013766 (20.4%) IPR025380 (20.4%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.4%) Thioredoxin domain (20.4%) Domain of unknown function DUF4369 (20.4%)" ADAMLCLSNCDK Bacteria Bacteria 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.1%) GO:0009099 (16.1%) GO:0008652 (0.1%)" GO:0005829 (17.5%) "GO:0004160 (16.4%) GO:0051537 (16.2%) GO:0000287 (15%)" "isoleucine biosynthetic process (16.1%) L-valine biosynthetic process (16.1%) amino acid biosynthetic process (0.1%)" cytosol (17.5%) "dihydroxy-acid dehydratase activity (16.4%) 2 iron, 2 sulfur cluster binding (16.2%) magnesium ion binding (15%)" "IPR000581 (17.4%) IPR020558 (17.3%) IPR037237 (17.2%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.4%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (17.3%) IlvD/EDD, N-terminal domain (17.2%)" EKLYQNDPSAVDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR005151 (50%) IPR029045 (50%)" "Tail specific protease (50%) ClpP/crotonase-like domain superfamily (50%)" CYAPGTNALEANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR024361 (50%)" "Immunoglobulin-like fold (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" DLVDPTQVK Bacteria Bacteria GO:0016020 (100%) membrane (100%) SSNTVVMVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.2%) GO:0019288 (18.2%)" "GO:0046429 (18.2%) GO:0051539 (18.2%) GO:0005506 (17.3%)" "terpenoid biosynthetic process (18.2%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.2%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.2%) 4 iron, 4 sulfur cluster binding (18.2%) iron ion binding (17.3%)" "IPR004588 (25.9%) IPR011005 (24.7%) IPR017178 (24.7%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (25.9%) Dihydropteroate synthase-like superfamily (24.7%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.7%)" LGLLSDLLR root "1.1.1.25 (86.4%) 2.7.11.1 (4.5%) 3.1.11.5 (4.5%)" "shikimate dehydrogenase (NADP(+)) (86.4%) non-specific serine/threonine protein kinase (4.5%) exodeoxyribonuclease V (4.5%)" "GO:0006281 (10.6%) GO:0000723 (10.3%) GO:0008652 (5%)" "GO:0016020 (20.1%) GO:0005829 (5%) GO:0005737 (0.6%)" "GO:0003678 (10.3%) GO:0004764 (5%) GO:0050661 (5%)" "DNA repair (10.6%) telomere maintenance (10.3%) amino acid biosynthetic process (5%)" "membrane (20.1%) cytosol (5%) cytoplasm (0.6%)" "DNA helicase activity (10.3%) shikimate 3-dehydrogenase (NADP+) activity (5%) NADP binding (5%)" "IPR003593 (9%) IPR010285 (8.5%) IPR027417 (8.5%)" "AAA+ ATPase domain (9%) DNA helicase Pif1-like, DEAD-box helicase domain (8.5%) P-loop containing nucleoside triphosphate hydrolase (8.5%)" KTNMQDLTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (25%) IPR012334 (25%) IPR033427 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) Domain of unknown function DUF5123 (25%)" AMLEDLAVLTGGVVLSEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.1%) GO:0005737 (16%) "GO:0005524 (17.1%) GO:0140662 (17.1%) GO:0016853 (16.7%)" protein refolding (17.1%) cytoplasm (16%) "ATP binding (17.1%) ATP-dependent protein folding chaperone (17.1%) isomerase activity (16.7%)" "IPR001844 (16.9%) IPR002423 (16.9%) IPR027409 (16.7%)" "Chaperonin Cpn60/GroEL (16.9%) Chaperonin Cpn60/GroEL/TCP-1 family (16.9%) GroEL-like apical domain superfamily (16.7%)" TGLNGDTFYCLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (38.2%) GO:0089702 (11.8%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (38.2%) undecaprenyl-phosphate glucose phosphotransferase activity (11.8%)" "IPR003362 (34.7%) IPR017475 (33.7%) IPR017473 (31.6%)" "Bacterial sugar transferase (34.7%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (33.7%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (31.6%)" MTWEDDFRK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.11.2 (100%) exodeoxyribonuclease III (100%) GO:0006284 (16.7%) "GO:0003677 (16.7%) GO:0003906 (16.7%) GO:0008081 (16.7%)" base-excision repair (16.7%) "DNA binding (16.7%) DNA-(apurinic or apyrimidinic site) endonuclease activity (16.7%) phosphoric diester hydrolase activity (16.7%)" "IPR004808 (20.3%) IPR005135 (20.3%) IPR020847 (20.3%)" "AP endonuclease 1 (20.3%) Endonuclease/exonuclease/phosphatase (20.3%) AP endonuclease 1, binding site (20.3%)" LESLNLTGK root 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) "GO:0006355 (3.6%) GO:0006952 (0.7%) GO:0051707 (0.7%)" GO:0005829 (29.2%) "GO:0003921 (29.2%) GO:0005524 (29.2%) GO:0003677 (3.9%)" "regulation of DNA-templated transcription (3.6%) defense response (0.7%) response to other organism (0.7%)" cytosol (29.2%) "GMP synthase activity (29.2%) ATP binding (29.2%) DNA binding (3.9%)" "IPR001674 (11.3%) IPR025777 (11.3%) IPR014729 (11.1%)" "GMP synthase, C-terminal (11.3%) GMP synthetase ATP pyrophosphatase domain (11.3%) Rossmann-like alpha/beta/alpha sandwich fold (11.1%)" NLSLSYSLPQSLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" SFVEPAPYGMVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0120147 (100%) formylglycine-generating oxidase activity (100%) "IPR005532 (26.4%) IPR051043 (25.3%) IPR016187 (24.2%)" "Sulfatase-modifying factor enzyme-like domain (26.4%) Sulfatase Modifying Factor and Kinase (25.3%) C-type lectin fold (24.2%)" YTAFLGCDNYTLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19%) "GO:0000155 (20.2%) GO:0003700 (20.2%) GO:0005524 (20.2%)" membrane (19%) "phosphorelay sensor kinase activity (20.2%) DNA-binding transcription factor activity (20.2%) ATP binding (20.2%)" "IPR001789 (7.8%) IPR003594 (7.8%) IPR003661 (7.8%)" "Signal transduction response regulator, receiver domain (7.8%) Histidine kinase/HSP90-like ATPase domain (7.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.8%)" LMLTLTR root "2.4.1.183 (62%) 3.1.-.- (14.7%) 6.2.1.26 (5.4%)" "alpha-1,3-glucan synthase (62%) Acting on ester bonds (14.7%) o-succinylbenzoate--CoA ligase (5.4%)" "GO:0070600 (6.8%) GO:0005975 (3.4%) GO:0007224 (1.5%)" "GO:0016020 (11.5%) GO:0009277 (6.8%) GO:0005886 (3.3%)" "GO:0047657 (6.8%) GO:0004553 (3.4%) GO:0022857 (2.2%)" "fungal-type cell wall (1->3)-alpha-glucan biosynthetic process (6.8%) carbohydrate metabolic process (3.4%) smoothened signaling pathway (1.5%)" "membrane (11.5%) fungal-type cell wall (6.8%) plasma membrane (3.3%)" "alpha-1,3-glucan synthase activity (6.8%) hydrolase activity, hydrolyzing O-glycosyl compounds (3.4%) transmembrane transporter activity (2.2%)" "IPR017853 (4.5%) IPR013534 (4.5%) IPR006047 (4.4%)" "Glycoside hydrolase superfamily (4.5%) Starch synthase, catalytic domain (4.5%) Glycosyl hydrolase family 13, catalytic domain (4.4%)" AATEAVFQKYPDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.2 (100%) UDP-glucose 4-epimerase (100%) GO:0006012 (33.3%) GO:0005829 (33.3%) GO:0003978 (33.3%) galactose metabolic process (33.3%) cytosol (33.3%) UDP-glucose 4-epimerase activity (33.3%) "IPR005886 (33.3%) IPR016040 (33.3%) IPR036291 (33.3%)" "UDP-glucose 4-epimerase (33.3%) NAD(P)-binding domain (33.3%) NAD(P)-binding domain superfamily (33.3%)" LAQAQSDYDSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LMPGLNACFVDVGYER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.1.26.- (90.9%) 3.1.4.- (9.1%)" "Endoribonucleases producing 5'-phosphomonoesters (90.9%) Phosphoric diester hydrolases (9.1%)" GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR004659 (25.2%) IPR019307 (25.2%) IPR003029 (24.8%)" "Ribonuclease E/G (25.2%) RNA-binding protein AU-1/Ribonuclease E/G (25.2%) S1 domain (24.8%)" EKDYFLMAQSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR001509 (34.1%) IPR050177 (34.1%) IPR036291 (31.8%)" "NAD-dependent epimerase/dehydratase (34.1%) Bifunctional lipid A modification and metabolic enzymes (34.1%) NAD(P)-binding domain superfamily (31.8%)" FSVSFYR root "2.3.1.- (62.1%) 7.2.2.12 (27.6%) 2.3.2.27 (6.9%)" "Transferring groups other than amino-acyl groups (62.1%) P-type Zn(2+) transporter (27.6%) RING-type E3 ubiquitin transferase (6.9%)" "GO:0030649 (16%) GO:0030001 (4%) GO:0006281 (0.8%)" "GO:0016020 (6%) GO:0005886 (5.2%) GO:0005576 (0.8%)" "GO:0034069 (16%) GO:0005524 (5.2%) GO:0016887 (4.4%)" "aminoglycoside antibiotic catabolic process (16%) metal ion transport (4%) DNA repair (0.8%)" "membrane (6%) plasma membrane (5.2%) extracellular region (0.8%)" "aminoglycoside N-acetyltransferase activity (16%) ATP binding (5.2%) ATP hydrolysis activity (4.4%)" "IPR000182 (8%) IPR016181 (8%) IPR025559 (8%)" "GNAT domain (8%) Acyl-CoA N-acyltransferase (8%) Enhanced intracellular survival protein domain (8%)" MTDLLLFWASK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.1 (100%) alpha-amylase (100%) "GO:0009313 (19.1%) GO:0043039 (15.1%)" "GO:0004556 (19.1%) GO:0004812 (15.1%) GO:0005524 (15.1%)" "oligosaccharide catabolic process (19.1%) tRNA aminoacylation (15.1%)" "alpha-amylase activity (19.1%) aminoacyl-tRNA ligase activity (15.1%) ATP binding (15.1%)" "IPR006047 (26.5%) IPR017853 (26%) IPR012947 (21%)" "Glycosyl hydrolase family 13, catalytic domain (26.5%) Glycoside hydrolase superfamily (26%) Threonyl/alanyl tRNA synthetase, SAD (21%)" TLNSTDFHFSSVQPNDEEVEEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DYLFMMMDELVK Pseudomonadati Bacteria Pseudomonadati GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.9%) IPR050073 (14.9%) IPR002034 (14.4%)" "Pyruvate carboxyltransferase (14.9%) 2-IPM synthase/homocitrate synthase-like (14.9%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.4%)" MNEALNTYETLTPENTDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YGDSNLDAVLNYQVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) LQAYLLLK root "4.2.1.136 (47.6%) 5.1.99.6 (47.6%) 2.4.1.17 (2.9%)" "ADP-dependent NAD(P)H-hydrate dehydratase (47.6%) NAD(P)H-hydrate epimerase (47.6%) glucuronosyltransferase (2.9%)" "GO:0110051 (14.4%) GO:0046496 (14.1%) GO:0002758 (1.2%)" "GO:0043541 (0.9%) GO:0005634 (0.6%) GO:0005886 (0.6%)" "GO:0005524 (14.7%) GO:0052855 (14.4%) GO:0052856 (14.4%)" "metabolite repair (14.4%) nicotinamide nucleotide metabolic process (14.1%) innate immune response-activating signaling pathway (1.2%)" "UDP-N-acetylglucosamine transferase complex (0.9%) nucleus (0.6%) plasma membrane (0.6%)" "ATP binding (14.7%) ADP-dependent NAD(P)H-hydrate dehydratase activity (14.4%) NAD(P)HX epimerase activity (14.4%)" "IPR000631 (13%) IPR029056 (13%) IPR004443 (12.8%)" "ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase (13%) Ribokinase-like (13%) YjeF N-terminal domain (12.8%)" YLGLADEEKYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.8.1.9 (100%) thioredoxin-disulfide reductase (NADPH) (100%) GO:0019430 (33.3%) GO:0005737 (33.3%) GO:0004791 (33.3%) removal of superoxide radicals (33.3%) cytoplasm (33.3%) thioredoxin-disulfide reductase (NADPH) activity (33.3%) "IPR005982 (20.1%) IPR008255 (20.1%) IPR023753 (20.1%)" "Thioredoxin reductase (20.1%) Pyridine nucleotide-disulphide oxidoreductase, class-II, active site (20.1%) FAD/NAD(P)-binding domain (20.1%)" EFLTPLTLSALTHKPVVSEFFSQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.4%) GO:0015941 (14.4%)" GO:0071513 (14.1%) "GO:0004632 (14.4%) GO:0004633 (14.4%) GO:0010181 (14.4%)" "coenzyme A biosynthetic process (14.4%) pantothenate catabolic process (14.4%)" phosphopantothenoylcysteine decarboxylase complex (14.1%) "phosphopantothenate--cysteine ligase activity (14.4%) phosphopantothenoylcysteine decarboxylase activity (14.4%) FMN binding (14.4%)" "IPR003382 (20.4%) IPR005252 (20.4%) IPR007085 (20.4%)" "Flavoprotein (20.4%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.4%) DNA/pantothenate metabolism flavoprotein, C-terminal (20.4%)" NLVLDTNCLLQLLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002716 (33.3%) IPR002850 (33.3%) IPR029060 (33.3%)" "PIN domain (33.3%) MJ1680-like (33.3%) PIN-like domain superfamily (33.3%)" YFVNTWSSYSHPYVFTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" YYGSDGNTTQYKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000917 (13.9%) GO:0043093 (13.9%) GO:0051258 (13.9%)" "GO:0005737 (13.9%) GO:0032153 (13.9%)" "GO:0005525 (15.3%) GO:0003924 (13.9%)" "division septum assembly (13.9%) FtsZ-dependent cytokinesis (13.9%) protein polymerization (13.9%)" "cytoplasm (13.9%) cell division site (13.9%)" "GTP binding (15.3%) GTPase activity (13.9%)" "IPR024757 (12.6%) IPR000158 (11.5%) IPR003008 (11.5%)" "Cell division protein FtsZ, C-terminal (12.6%) Cell division protein FtsZ (11.5%) Tubulin/FtsZ, GTPase domain (11.5%)" NDTEQLKEVTSEYGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.99.17 (100%) phosphomethylpyrimidine synthase (100%) "GO:0009228 (16.7%) GO:0009229 (16.7%)" GO:0005829 (16.7%) "GO:0008270 (16.7%) GO:0051539 (16.7%) GO:0016830 (8.3%)" "thiamine biosynthetic process (16.7%) thiamine diphosphate biosynthetic process (16.7%)" cytosol (16.7%) "zinc ion binding (16.7%) 4 iron, 4 sulfur cluster binding (16.7%) carbon-carbon lyase activity (8.3%)" "IPR002817 (25%) IPR025747 (25%) IPR037509 (25%)" "Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B (25%) ThiC-associated domain (25%) Phosphomethylpyrimidine synthase (25%)" VTLTFDYYNKLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" TDSFNVNFFLDNLEQNQNNNATR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" EYASSSASSSLVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.3%) IPR051802 (19.3%) IPR001599 (17.5%)" "Macroglobulin domain (19.3%) Alpha-2-macroglobulin-like (19.3%) Alpha-2-macroglobulin (17.5%)" DMQETEAPWPAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) LNGTTLAWDNNDYALLWAVCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (42.9%) "GO:0052689 (42.9%) GO:0004557 (14.3%)" cell outer membrane (42.9%) "carboxylic ester hydrolase activity (42.9%) alpha-galactosidase activity (14.3%)" "IPR032812 (25.6%) IPR044060 (25.6%) IPR011050 (24.4%)" "SbsA, Ig-like domain (25.6%) Bacterial repeat domain (25.6%) Pectin lyase fold/virulence factor (24.4%)" NWSLHVEYNGGLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) IPR036777 (100%) Nucleoside-specific channel-forming protein, Tsx-like superfamily (100%) QSLDALTPLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.51 (100%) prephenate dehydratase (100%) GO:0009094 (33.3%) GO:0005737 (33.3%) GO:0004664 (33.3%) L-phenylalanine biosynthetic process (33.3%) cytoplasm (33.3%) prephenate dehydratase activity (33.3%) "IPR002912 (26%) IPR001086 (25.3%) IPR045865 (24.7%)" "ACT domain (26%) Prephenate dehydratase (25.3%) ACT-like domain (24.7%)" VLFLATANDLSVLPRPLLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.6%) GO:0034605 (12.3%)" GO:0005737 (12.3%) "GO:0004176 (12.6%) GO:0004252 (12.6%) GO:0005524 (12.6%)" "protein quality control for misfolded or incompletely synthesized proteins (12.6%) cellular response to heat (12.3%)" cytoplasm (12.3%) "ATP-dependent peptidase activity (12.6%) serine-type endopeptidase activity (12.6%) ATP binding (12.6%)" "IPR003593 (7.6%) IPR003959 (7.6%) IPR027065 (7.6%)" "AAA+ ATPase domain (7.6%) ATPase, AAA-type, core (7.6%) Lon protease (7.6%)" EDGSNKLDNVLEVSTLDGTVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) GSDGGPDASNMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0034605 (24.7%) GO:0006508 (0.6%)" GO:0005737 (24.7%) "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0008233 (0.6%)" "cellular response to heat (24.7%) proteolysis (0.6%)" cytoplasm (24.7%) "ATP binding (24.7%) ATP hydrolysis activity (24.7%) peptidase activity (0.6%)" "IPR003593 (10.3%) IPR003959 (10.3%) IPR019489 (10.3%)" "AAA+ ATPase domain (10.3%) ATPase, AAA-type, core (10.3%) Clp ATPase, C-terminal (10.3%)" GLFPAACDFTTDLHSMGQWLQQGER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.3%) GO:0006096 (14.3%) GO:0051156 (14.3%)" GO:0005829 (14.3%) "GO:0004347 (14.3%) GO:0048029 (14.3%) GO:0097367 (14%)" "gluconeogenesis (14.3%) glycolytic process (14.3%) glucose 6-phosphate metabolic process (14.3%)" cytosol (14.3%) "glucose-6-phosphate isomerase activity (14.3%) monosaccharide binding (14.3%) carbohydrate derivative binding (14%)" "IPR001672 (20.4%) IPR035482 (20.4%) IPR018189 (19.9%)" "Phosphoglucose isomerase (PGI) (20.4%) Phosphoglucose isomerase, SIS domain 2 (20.4%) Phosphoglucose isomerase, conserved site (19.9%)" KPDTTFCVFCQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.53 (100%) endopeptidase La (100%) "GO:0006515 (12.5%) GO:0034605 (12.5%)" GO:0005737 (12.5%) "GO:0004176 (12.5%) GO:0004252 (12.5%) GO:0005524 (12.5%)" "protein quality control for misfolded or incompletely synthesized proteins (12.5%) cellular response to heat (12.5%)" cytoplasm (12.5%) "ATP-dependent peptidase activity (12.5%) serine-type endopeptidase activity (12.5%) ATP binding (12.5%)" "IPR003111 (7.3%) IPR003593 (7.3%) IPR003959 (7.3%)" "Lon protease, N-terminal domain (7.3%) AAA+ ATPase domain (7.3%) ATPase, AAA-type, core (7.3%)" VCNLSYLQTDWYLDQMMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR052724 (50.7%) IPR021280 (49.3%)" "Glycosyltransferase 117 domain-containing protein (50.7%) Protein O-mannosyl-transferase TMEM260-like (49.3%)" VYLSLTNQPGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015679 (20%) GO:0060003 (20%)" "GO:0016020 (20%) GO:0030313 (20%)" GO:0022857 (20%) "plasma membrane copper ion transport (20%) copper ion export (20%)" "membrane (20%) cell envelope (20%)" transmembrane transporter activity (20%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051909 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Membrane Fusion Protein Cation Efflux System (33.3%)" LELNDYQLEQHAVDELLESLEDTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.5%) GO:0005829 (16.5%) "GO:0003677 (16.5%) GO:0004527 (16.5%) GO:0005524 (16.5%)" recombinational repair (16.5%) cytosol (16.5%) "DNA binding (16.5%) exonuclease activity (16.5%) ATP binding (16.5%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" NSFAHGWSPLASHYLEVTLQPGESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33%) "GO:0016757 (33%) GO:0030246 (33%) GO:0016740 (1%)" carbohydrate metabolic process (33%) "glycosyltransferase activity (33%) carbohydrate binding (33%) transferase activity (1%)" "IPR010383 (12.7%) IPR033432 (12.7%) IPR052047 (12.7%)" "Glycosyl hydrolase 94, supersandwich domain (12.7%) Glycosyl hydrolase 94, catalytic domain (12.7%) Glycosyl Hydrolase 94 Enzymes (12.7%)" VLLYEVESNDTWVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) TADLNLNTNGYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) ELNVLSQSQTPPFTLEDNTDGGDDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004815 (20%) GO:0005524 (20%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) aspartate-tRNA ligase activity (20%) ATP binding (20%)" "IPR004364 (9.2%) IPR004365 (9.2%) IPR004524 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (9.2%) Aspartate-tRNA ligase, type 1 (9.2%)" TYDYDEEFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VSLNSAALR root "4.3.2.10 (93.5%) 4.1.3.- (6.5%)" "imidazole glycerol-phosphate synthase (93.5%) Oxo-acid-lyases (6.5%)" GO:0000105 (25%) "GO:0005737 (24.4%) GO:0005882 (0.9%)" "GO:0000107 (25%) GO:0016829 (24.7%)" L-histidine biosynthetic process (25%) "cytoplasm (24.4%) intermediate filament (0.9%)" "imidazoleglycerol-phosphate synthase activity (25%) lyase activity (24.7%)" "IPR006062 (19.8%) IPR050064 (19.8%) IPR011060 (19.5%)" "Histidine biosynthesis protein (19.8%) Imidazole glycerol phosphate synthase HisA/HisF (19.8%) Ribulose-phosphate binding barrel (19.5%)" SEHFELNGYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" FHLLNMNLTDVKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.7%) IPR025896 (16.7%) IPR026906 (16.7%)" "Peptidase C10, streptopain (16.7%) Spi protease inhibitor (16.7%) BspA-type LRR region (16.7%)" NVEVSQGFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR032533 (33.8%) IPR049208 (33.8%) IPR011004 (32.4%)" "Domain of unknown function DUF4954 (33.8%) Domain of unknown function DUF6819 (33.8%) Trimeric LpxA-like superfamily (32.4%)" LTAHLLDLLGEASQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (32.7%) GO:0016020 (34.6%) GO:0003677 (32.7%) regulation of DNA-templated transcription (32.7%) membrane (34.6%) DNA binding (32.7%) "IPR016032 (47.2%) IPR036388 (47.2%) IPR000792 (5.6%)" "Signal transduction response regulator, C-terminal effector (47.2%) Winged helix-like DNA-binding domain superfamily (47.2%) Transcription regulator LuxR, C-terminal (5.6%)" TKLEDALTAAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" NDVTDLCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) DMPLVLRPSER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (20%) IPR051802 (20%) IPR001599 (18.9%)" "Macroglobulin domain (20%) Alpha-2-macroglobulin-like (20%) Alpha-2-macroglobulin (18.9%)" QKVDLLDAAQMLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.7%) GO:0006526 (13.5%) GO:0006221 (12.9%)" GO:0005737 (14.7%) "GO:0004088 (14.7%) GO:0005524 (14.7%) GO:0046872 (13.5%)" "glutamine metabolic process (14.7%) L-arginine biosynthetic process (13.5%) pyrimidine nucleotide biosynthetic process (12.9%)" cytoplasm (14.7%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.7%) ATP binding (14.7%) metal ion binding (13.5%)" "IPR011607 (11%) IPR036914 (11%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (11%) Methylglyoxal synthase-like domain superfamily (11%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" AFESLYETNPVTGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0120147 (100%) formylglycine-generating oxidase activity (100%) "IPR005532 (26.3%) IPR051043 (26.3%) IPR016187 (23.8%)" "Sulfatase-modifying factor enzyme-like domain (26.3%) Sulfatase Modifying Factor and Kinase (26.3%) C-type lectin fold (23.8%)" NGEAADLMFFLDNLFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (22.9%) GO:0045259 (22.9%)" "GO:0005524 (22.9%) GO:0046933 (22.9%) GO:0016787 (8.5%)" "plasma membrane (22.9%) proton-transporting ATP synthase complex (22.9%)" "ATP binding (22.9%) proton-transporting ATP synthase activity, rotational mechanism (22.9%) hydrolase activity (8.5%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" AVQDLLDAHNSDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (1.5%) "GO:0000287 (19.7%) GO:0004743 (19.7%) GO:0005524 (19.7%)" response to stress (1.5%) "magnesium ion binding (19.7%) pyruvate kinase activity (19.7%) ATP binding (19.7%)" "IPR001697 (11.6%) IPR015793 (11.6%) IPR015795 (11.6%)" "Pyruvate kinase (11.6%) Pyruvate kinase, barrel (11.6%) Pyruvate kinase, C-terminal (11.6%)" TVDLSLPVGLSYEYQNLVFDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027385 (100%) Outer membrane protein, beta-barrel domain (100%) WMGQLAGDCVDLNTENDYVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (58.8%) "GO:0016787 (23.5%) GO:0016829 (17.6%)" carbohydrate metabolic process (58.8%) "hydrolase activity (23.5%) lyase activity (17.6%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" MLGTGGPDYTLPAEFVYPQLFHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR002130 (25.4%) IPR020892 (25.4%) IPR044666 (25.4%)" "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain (25.4%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (25.4%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like (25.4%)" LLALVDACSAFADK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales AAQNSGGLTGLPTGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.3 (100%) DNA 5'-3' helicase (100%) "GO:0006269 (12.1%) GO:0006260 (1%)" "GO:0005829 (13.1%) GO:1990077 (12.1%)" "GO:0003678 (13.1%) GO:0005524 (13.1%) GO:0003677 (12.1%)" "DNA replication, synthesis of primer (12.1%) DNA replication (1%)" "cytosol (13.1%) primosome complex (12.1%)" "DNA helicase activity (13.1%) ATP binding (13.1%) DNA binding (12.1%)" "IPR007694 (16%) IPR007693 (14.8%) IPR016136 (14.8%)" "DNA helicase, DnaB-like, C-terminal (16%) DNA helicase, DnaB-like, N-terminal (14.8%) DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal (14.8%)" LFTGATDR root GO:0044718 (5.9%) "GO:0009279 (64.7%) GO:0005737 (5.9%) GO:0005886 (5.9%)" "GO:0015344 (5.9%) GO:0016791 (5.9%) GO:0046872 (5.9%)" siderophore transmembrane transport (5.9%) "cell outer membrane (64.7%) cytoplasm (5.9%) plasma membrane (5.9%)" "siderophore uptake transmembrane transporter activity (5.9%) phosphatase activity (5.9%) metal ion binding (5.9%)" "IPR012910 (12.4%) IPR023996 (12.4%) IPR023997 (12.4%)" "TonB-dependent receptor, plug domain (12.4%) TonB-dependent outer membrane protein, SusC/RagA (12.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.4%)" TMFGTACALAAAADR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0034605 (24.7%) GO:0006508 (0.6%)" GO:0005737 (24.7%) "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0008233 (0.6%)" "cellular response to heat (24.7%) proteolysis (0.6%)" cytoplasm (24.7%) "ATP binding (24.7%) ATP hydrolysis activity (24.7%) peptidase activity (0.6%)" "IPR003593 (10.3%) IPR003959 (10.3%) IPR019489 (10.3%)" "AAA+ ATPase domain (10.3%) ATPase, AAA-type, core (10.3%) Clp ATPase, C-terminal (10.3%)" WTPAALQYLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (20%) GO:0042026 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0016887 (20%)" "cellular response to heat (20%) protein refolding (20%)" cytoplasm (20%) "ATP binding (20%) ATP hydrolysis activity (20%)" "IPR003593 (8.5%) IPR003959 (8.5%) IPR004176 (8.5%)" "AAA+ ATPase domain (8.5%) ATPase, AAA-type, core (8.5%) Clp, repeat (R) N-terminal domain (8.5%)" LDEKDFFGLLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (50%) GO:0004674 (50%) cytosol (50%) protein serine/threonine kinase activity (50%) "IPR017508 (54.5%) IPR052028 (45.5%)" "HipA, N-terminal subdomain 1 (54.5%) HipA Serine/Threonine-Protein Kinase (45.5%)" MSPEEHLAHLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.4%) IPR002034 (14.4%) IPR013709 (14.4%)" "Pyruvate carboxyltransferase (14.4%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.4%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.4%)" VGLYLPGGTAPLFSTVLMLATPAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (25.4%) IPR012131 (25.4%) IPR016161 (24.6%)" "Histidinol dehydrogenase, conserved site (25.4%) Histidinol dehydrogenase (25.4%) Aldehyde/histidinol dehydrogenase (24.6%)" VLSEGPLR root "2.4.1.- (50%) 3.2.1.24 (50%)" "Hexosyltransferases (50%) alpha-mannosidase (50%)" "GO:0006417 (10.3%) GO:0000278 (3.1%) GO:0006412 (3.1%)" "GO:0016281 (11.3%) GO:0005829 (5.2%) GO:0000329 (1%)" "GO:0003743 (11.3%) GO:0003729 (9.3%) GO:0000340 (5.2%)" "regulation of translation (10.3%) mitotic cell cycle (3.1%) translation (3.1%)" "eukaryotic translation initiation factor 4F complex (11.3%) cytosol (5.2%) fungal-type vacuole membrane (1%)" "translation initiation factor activity (11.3%) mRNA binding (9.3%) RNA 7-methylguanosine cap binding (5.2%)" "IPR032342 (26.4%) IPR003890 (8.5%) IPR016024 (8.5%)" "Protein of unknown function DUF4861 (26.4%) MIF4G-like, type 3 (8.5%) Armadillo-type fold (8.5%)" LYDLANR root "1.1.1.49 (88.4%) 2.1.1.198 (6.5%) 1.1.1.363 (1.9%)" "glucose-6-phosphate dehydrogenase (NADP(+)) (88.4%) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (6.5%) glucose-6-phosphate dehydrogenase [NAD(P)(+)] (1.9%)" "GO:0006006 (17.3%) GO:0009051 (17.3%) GO:0006508 (0.4%)" "GO:0005829 (17.4%) GO:0005737 (1.5%) GO:0016020 (0.5%)" "GO:0050661 (17.3%) GO:0004345 (17.3%) GO:0070677 (1.3%)" "glucose metabolic process (17.3%) pentose-phosphate shunt, oxidative branch (17.3%) proteolysis (0.4%)" "cytosol (17.4%) cytoplasm (1.5%) membrane (0.5%)" "NADP binding (17.3%) glucose-6-phosphate dehydrogenase activity (17.3%) rRNA (cytosine-2'-O-)-methyltransferase activity (1.3%)" "IPR036291 (15.8%) IPR022674 (15.7%) IPR001282 (15.7%)" "NAD(P)-binding domain superfamily (15.8%) Glucose-6-phosphate dehydrogenase, NAD-binding (15.7%) Glucose-6-phosphate dehydrogenase (15.7%)" DVMMTDLLSGR root 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.2%) IPR010918 (11.2%) IPR040707 (11.2%)" "Phosphoribosylformylglycinamidine synthase PurL (11.2%) PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.2%)" VNPSEQALHYLYLLSMDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.2%) IPR002890 (19.2%) IPR051802 (19.2%)" "Alpha-2-macroglobulin (19.2%) Macroglobulin domain (19.2%) Alpha-2-macroglobulin-like (19.2%)" GADVSWLTEMEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (40.7%) "GO:0015926 (40.7%) GO:0031218 (18.6%)" pectin catabolic process (40.7%) "glucosidase activity (40.7%) arabinogalactan endo-1,4-beta-galactosidase activity (18.6%)" "IPR011683 (51.1%) IPR017853 (48.9%)" "Glycosyl hydrolase family 53 (51.1%) Glycoside hydrolase superfamily (48.9%)" LDDLSEWTDKAGLPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (8.2%) IPR007121 (8.2%) IPR007641 (8.2%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.2%) RNA polymerase, beta subunit, conserved site (8.2%) RNA polymerase Rpb2, domain 7 (8.2%)" TPLASLSLAAQMLNDTSVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0007234 (15.8%) "GO:0005886 (15.8%) GO:0016020 (2.6%)" "GO:0000155 (18.4%) GO:0000156 (15.8%) GO:0005524 (15.8%)" osmosensory signaling via phosphorelay pathway (15.8%) "plasma membrane (15.8%) membrane (2.6%)" "phosphorelay sensor kinase activity (18.4%) phosphorelay response regulator activity (15.8%) ATP binding (15.8%)" "IPR003661 (15.9%) IPR036097 (15.9%) IPR003594 (13.6%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (15.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily (15.9%) Histidine kinase/HSP90-like ATPase domain (13.6%)" MFFFWYKPEER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.8.4.4 (100%) [ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase (100%) GO:0032259 (1.4%) GO:0005840 (0.4%) "GO:0051539 (32.3%) GO:0005506 (31.9%) GO:0003824 (30.5%)" methylation (1.4%) ribosome (0.4%) "4 iron, 4 sulfur cluster binding (32.3%) iron ion binding (31.9%) catalytic activity (30.5%)" "IPR007197 (14.4%) IPR013704 (14.4%) IPR020612 (14.4%)" "Radical SAM (14.4%) UPF0313, N-terminal (14.4%) Methylthiotransferase, conserved site (14.4%)" VWVNPEGGWCGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (43.3%) "GO:0015926 (43.3%) GO:0031218 (13.4%)" pectin catabolic process (43.3%) "glucosidase activity (43.3%) arabinogalactan endo-1,4-beta-galactosidase activity (13.4%)" "IPR011683 (51.8%) IPR017853 (48.2%)" "Glycosyl hydrolase family 53 (51.8%) Glycoside hydrolase superfamily (48.2%)" SEGFTDYVDMTFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0046873 (50%) membrane (50%) metal ion transmembrane transporter activity (50%) "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" GQNVEDWGQVMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034707 (46%) GO:0016020 (4%)" "GO:0005254 (46%) GO:0015108 (4%)" "chloride channel complex (46%) membrane (4%)" "chloride channel activity (46%) chloride transmembrane transporter activity (4%)" "IPR000644 (20.7%) IPR001807 (20.7%) IPR050368 (20.7%)" "CBS domain (20.7%) Chloride channel (20.7%) Voltage-gated ClC-type chloride channel (20.7%)" GQLLLFK root "3.2.1.26 (21.2%) 3.1.1.4 (13.5%) 1.2.4.4 (7.7%)" "beta-fructofuranosidase (21.2%) phospholipase A2 (13.5%) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (7.7%)" "GO:0006351 (1.3%) GO:0006904 (1.3%) GO:0007032 (1.3%)" "GO:0016020 (8.6%) GO:0005737 (4.7%) GO:0005886 (3.5%)" "GO:0008270 (3.5%) GO:0003677 (2.8%) GO:0046872 (2.1%)" "DNA-templated transcription (1.3%) vesicle docking involved in exocytosis (1.3%) endosome organization (1.3%)" "membrane (8.6%) cytoplasm (4.7%) plasma membrane (3.5%)" "zinc ion binding (3.5%) DNA binding (2.8%) metal ion binding (2.1%)" "IPR026728 (15.9%) IPR000620 (2.6%) IPR024370 (2.5%)" "Bridge-like lipid transfer protein family member 3A/B (15.9%) EamA domain (2.6%) PBP domain (2.5%)" NYLSDEELSQLNALTTSFLDLAESR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR011204 (100%) Virulence protein RhuM-like (100%) QLGVEGLVTALHDVPLGEVWTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.8 (100%) mannonate dehydratase (100%) GO:0042840 (25%) "GO:0008198 (25%) GO:0008927 (25%) GO:0030145 (25%)" D-glucuronate catabolic process (25%) "ferrous iron binding (25%) mannonate dehydratase activity (25%) manganese ion binding (25%)" "IPR004628 (50.8%) IPR036237 (49.2%)" "Mannonate dehydratase (50.8%) Xylose isomerase-like superfamily (49.2%)" VNMLELNTTPGMTVTSFLPQQVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.6%) GO:0008360 (13.1%) GO:0009252 (13.1%)" GO:0005737 (13.1%) "GO:0005524 (15.4%) GO:0008716 (15.4%) GO:0046872 (15.4%)" "cell wall organization (14.6%) regulation of cell shape (13.1%) peptidoglycan biosynthetic process (13.1%)" cytoplasm (13.1%) "ATP binding (15.4%) D-alanine-D-alanine ligase activity (15.4%) metal ion binding (15.4%)" "IPR011095 (15.3%) IPR011761 (15.3%) IPR000291 (14.5%)" "D-alanine--D-alanine ligase, C-terminal (15.3%) ATP-grasp fold (15.3%) D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.5%)" NAYAYYEDGDESVLPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.4%) GO:0009099 (16.4%)" GO:0005829 (17.1%) "GO:0000287 (16.4%) GO:0004160 (16.4%) GO:0051537 (16.4%)" "isoleucine biosynthetic process (16.4%) L-valine biosynthetic process (16.4%)" cytosol (17.1%) "magnesium ion binding (16.4%) dihydroxy-acid dehydratase activity (16.4%) 2 iron, 2 sulfur cluster binding (16.4%)" "IPR000581 (17.3%) IPR056740 (17.3%) IPR004404 (16.5%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.3%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.3%) Dihydroxy-acid dehydratase (16.5%)" QDAFDKVLADFLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (13.9%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (13.9%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (8%) IPR012162 (8%) IPR015847 (8%)" "Exoribonuclease, phosphorolytic domain 1 (8%) Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 2 (8%)" QLDNELLETGKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.8%) GO:0005886 (19.8%) "GO:0003723 (20.5%) GO:0016787 (20.2%) GO:0004521 (19.8%)" mRNA catabolic process (19.8%) plasma membrane (19.8%) "RNA binding (20.5%) hydrolase activity (20.2%) RNA endonuclease activity (19.8%)" "IPR004087 (12.6%) IPR004088 (12.6%) IPR003607 (12.5%)" "K Homology domain (12.6%) K Homology domain, type 1 (12.6%) HD/PDEase domain (12.5%)" VAWDWWNDWNLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.2.1.22 (66.7%) 3.2.1.20 (22.2%) 3.2.1.- (11.1%)" "alpha-galactosidase (66.7%) alpha-glucosidase (22.2%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (11.1%)" GO:0016020 (0.3%) "GO:0030246 (36.7%) GO:0016798 (33.5%) GO:0008237 (25.7%)" membrane (0.3%) "carbohydrate binding (36.7%) hydrolase activity, acting on glycosyl bonds (33.5%) metallopeptidase activity (25.7%)" "IPR019563 (11.7%) IPR029486 (11.7%) IPR052720 (11.7%)" "Glycosyl-hydrolase 97, catalytic domain (11.7%) Glycosyl-hydrolase 97, N-terminal domain (11.7%) Glycosyl Hydrolase Family 97 (11.7%)" EKVEQYLNVFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" LNASTVAAPLATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0046813 (50%) GO:0009279 (50%) receptor-mediated virion attachment to host cell (50%) cell outer membrane (50%) "IPR019734 (26.4%) IPR009003 (25.3%) IPR011990 (24.1%)" "Tetratricopeptide repeat (26.4%) Peptidase S1, PA clan (25.3%) Tetratricopeptide-like helical domain superfamily (24.1%)" TGGDLNKFFDNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009636 (24.4%) GO:0005886 (25.6%) "GO:0042910 (25.6%) GO:0015562 (24.4%)" response to toxic substance (24.4%) plasma membrane (25.6%) "xenobiotic transmembrane transporter activity (25.6%) efflux transmembrane transporter activity (24.4%)" "IPR001036 (33.9%) IPR027463 (33.9%) IPR004764 (32.2%)" "Acriflavin resistance protein (33.9%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.9%) Multidrug resistance protein MdtF-like (32.2%)" ASLQYLNLFLQEVDKVDWAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.5%) IPR011990 (32.3%) IPR012944 (32.3%)" "SusD-like, N-terminal (35.5%) Tetratricopeptide-like helical domain superfamily (32.3%) RagB/SusD domain (32.3%)" NDLLSPENLVYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044281 (32.7%) "GO:0016625 (33.7%) GO:0030976 (33.7%)" small molecule metabolic process (32.7%) "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (33.7%) thiamine pyrophosphate binding (33.7%)" "IPR011766 (33.3%) IPR029061 (33.3%) IPR051457 (33.3%)" "Thiamine pyrophosphate enzyme, TPP-binding (33.3%) Thiamin diphosphate-binding fold (33.3%) 2-oxoacid:ferredoxin oxidoreductase (33.3%)" GTAENPETFFTHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.2.7.1 (89.3%) 1.2.-.- (3.6%) 1.2.1.51 (3.6%)" "pyruvate synthase (89.3%) Acting on the aldehyde or oxo group of donors (3.6%) pyruvate dehydrogenase (NADP(+)) (3.6%)" "GO:0006979 (14.7%) GO:0022900 (14.6%) GO:0044281 (12%)" "GO:0005506 (14.6%) GO:0030976 (14.6%) GO:0051539 (14.6%)" "response to oxidative stress (14.7%) electron transport chain (14.6%) small molecule metabolic process (12%)" "iron ion binding (14.6%) thiamine pyrophosphate binding (14.6%) 4 iron, 4 sulfur cluster binding (14.6%)" "IPR002880 (7.8%) IPR033412 (7.8%) IPR050722 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Pyruvate:ferredoxin oxidoreductase, core domain II (7.8%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.8%)" VPLFVNEGETLQLDTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0043043 (33.3%) GO:0005829 (33.3%) GO:0003746 (33.3%) peptide biosynthetic process (33.3%) cytosol (33.3%) translation elongation factor activity (33.3%) "IPR001059 (11.1%) IPR008991 (11.1%) IPR011768 (11.1%)" "Translation elongation factor P/YeiP, central (11.1%) Translation protein SH3-like domain superfamily (11.1%) Translation elongation factor P (11.1%)" SEYHDYPGEYSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.-.- (50%) 3.4.14.5 (50%)" "Acting on peptide bonds (peptidases) (50%) dipeptidyl-peptidase IV (50%)" GO:0006508 (34%) "GO:0008239 (34%) GO:0008236 (32%)" proteolysis (34%) "dipeptidyl-peptidase activity (34%) serine-type peptidase activity (32%)" "IPR002469 (26%) IPR050278 (26%) IPR001375 (24.4%)" "Dipeptidylpeptidase IV, N-terminal domain (26%) Serine protease S9B/DPPIV (26%) Peptidase S9, prolyl oligopeptidase, catalytic domain (24.4%)" TSPDELTSGNYWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35%) IPR033985 (35%) IPR012944 (30%)" "Tetratricopeptide-like helical domain superfamily (35%) SusD-like, N-terminal (35%) RagB/SusD domain (30%)" FSLEPQMVLSQLDVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.1 (100%) NAD(+) synthase (glutamine-hydrolyzing) (100%) GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.8%) IPR003694 (14.8%) IPR014445 (14.8%)" "Carbon-nitrogen hydrolase (14.8%) NAD(+) synthetase (14.8%) Glutamine-dependent NAD(+) synthetase (14.8%)" DVSYLNPEHVGDVYTDRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) SLFETVLSVETPNEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.9%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.9%)" "IPR001672 (20.6%) IPR035482 (20.6%) IPR018189 (19.9%)" "Phosphoglucose isomerase (PGI) (20.6%) Phosphoglucose isomerase, SIS domain 2 (20.6%) Phosphoglucose isomerase, conserved site (19.9%)" VNVNWLDEVFNDRAPLQSYELSLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (2.9%) GO:0009279 (94.3%) GO:0015344 (2.9%) siderophore transmembrane transport (2.9%) cell outer membrane (94.3%) siderophore uptake transmembrane transporter activity (2.9%) "IPR012910 (12.9%) IPR023997 (12.9%) IPR039426 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%) TonB-dependent receptor-like (12.9%)" GVSGSNLADNHYADFAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" GPQGTLYGQNSEGGLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006826 (47.1%) GO:0006811 (2.9%)" GO:0009279 (50%) "iron ion transport (47.1%) monoatomic ion transport (2.9%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" YGVDAVMLGR Bacteria Bacteria 1.3.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) "GO:0017150 (33.4%) GO:0050660 (33.2%) GO:0000049 (30.2%)" "tRNA dihydrouridine synthase activity (33.4%) flavin adenine dinucleotide binding (33.2%) tRNA binding (30.2%)" "IPR035587 (17%) IPR013785 (16.9%) IPR018517 (16.9%)" "DUS-like, FMN-binding domain (17%) Aldolase-type TIM barrel (16.9%) tRNA-dihydrouridine synthase, conserved site (16.9%)" HLGGLGLGGGTLAGLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.33 (100%) pantothenate kinase (100%) GO:0015937 (25%) GO:0005829 (25%) "GO:0004594 (25%) GO:0005524 (25%)" coenzyme A biosynthetic process (25%) cytosol (25%) "pantothenate kinase activity (25%) ATP binding (25%)" "IPR004567 (50%) IPR043129 (50%)" "Type II pantothenate kinase (50%) ATPase, nucleotide binding domain (50%)" NLLAQLK root "2.3.1.48 (58.5%) 2.8.3.6 (8.2%) 2.7.13.3 (4.1%)" "histone acetyltransferase (58.5%) 3-oxoadipate CoA-transferase (8.2%) histidine kinase (4.1%)" "GO:0045944 (6.6%) GO:0061035 (2.4%) GO:1903010 (2.4%)" "GO:0140672 (6.7%) GO:0005634 (6.6%) GO:0005737 (5.8%)" "GO:0043992 (5.1%) GO:0010484 (1.8%) GO:0005524 (1.6%)" "positive regulation of transcription by RNA polymerase II (6.6%) regulation of cartilage development (2.4%) regulation of bone development (2.4%)" "ATAC complex (6.7%) nucleus (6.6%) cytoplasm (5.8%)" "histone H3K9 acetyltransferase activity (5.1%) histone H3 acetyltransferase activity (1.8%) ATP binding (1.6%)" "IPR037800 (6.7%) IPR001487 (6.6%) IPR036427 (6.6%)" "Histone acetyltransferase GCN5 (6.7%) Bromodomain (6.6%) Bromodomain-like superfamily (6.6%)" TLTLETGK root "2.7.7.8 (98.8%) 2.7.13.3 (0.2%) 3.1.13.1 (0.2%)" "polyribonucleotide nucleotidyltransferase (98.8%) histidine kinase (0.2%) exoribonuclease II (0.2%)" "GO:0006402 (14%) GO:0006396 (13.8%) GO:0000958 (0.1%)" "GO:0005829 (14.1%) GO:0005739 (0.1%) GO:0009570 (0.1%)" "GO:0003723 (14.1%) GO:0000175 (14.1%) GO:0004654 (14.1%)" "mRNA catabolic process (14%) RNA processing (13.8%) mitochondrial mRNA catabolic process (0.1%)" "cytosol (14.1%) mitochondrion (0.1%) chloroplast stroma (0.1%)" "RNA binding (14.1%) 3'-5'-RNA exonuclease activity (14.1%) polyribonucleotide nucleotidyltransferase activity (14.1%)" "IPR001247 (7.8%) IPR012162 (7.8%) IPR015847 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) Polyribonucleotide nucleotidyltransferase (7.8%) Exoribonuclease, phosphorolytic domain 2 (7.8%)" GLRYDLTVPFAR root 6.1.1.21 (100%) histidine--tRNA ligase (100%) "GO:0006427 (24.8%) GO:0006412 (0%) GO:0032543 (0%)" "GO:0005737 (24.9%) GO:0005739 (0%) GO:0005829 (0%)" "GO:0004821 (25%) GO:0005524 (24.9%) GO:0016874 (0.1%)" "histidyl-tRNA aminoacylation (24.8%) translation (0%) mitochondrial translation (0%)" "cytoplasm (24.9%) mitochondrion (0%) cytosol (0%)" "histidine-tRNA ligase activity (25%) ATP binding (24.9%) ligase activity (0.1%)" "IPR041715 (12.7%) IPR045864 (12.7%) IPR015807 (12.6%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (12.7%) Histidine-tRNA ligase (12.6%)" VLNLDLQNLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016758 (100%) hexosyltransferase activity (100%) IPR004629 (100%) Glycosyl transferase WecG/TagA/CpsF (100%) LGFEDGER root "7.4.2.8 (85.1%) 4.6.1.1 (9.5%) 1.4.3.- (1.4%)" "protein-secreting ATPase (85.1%) adenylate cyclase (9.5%) With oxygen as acceptor (1.4%)" "GO:0006605 (8.6%) GO:0017038 (8.6%) GO:0043952 (8.6%)" "GO:0005886 (9.6%) GO:0005829 (9%) GO:0031522 (8.6%)" "GO:0005524 (10.1%) GO:0046872 (9.6%) GO:0003924 (1.1%)" "protein targeting (8.6%) protein import (8.6%) protein transport by the Sec complex (8.6%)" "plasma membrane (9.6%) cytosol (9%) cell envelope Sec protein transport complex (8.6%)" "ATP binding (10.1%) metal ion binding (9.6%) GTPase activity (1.1%)" "IPR027417 (7.4%) IPR000185 (6.7%) IPR001650 (6.7%)" "P-loop containing nucleoside triphosphate hydrolase (7.4%) Protein translocase subunit SecA (6.7%) Helicase, C-terminal domain-like (6.7%)" NLSSLFPPLEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.2%) "GO:0000155 (25.3%) GO:0003700 (25.3%) GO:0043565 (25.3%)" membrane (24.2%) "phosphorelay sensor kinase activity (25.3%) DNA-binding transcription factor activity (25.3%) sequence-specific DNA binding (25.3%)" "IPR011110 (12.4%) IPR011123 (12.4%) IPR018060 (12.4%)" "Two component regulator propeller (12.4%) Two component regulator three Y (12.4%) AraC-like, DNA binding HTH domain (12.4%)" GTLASYSLDANRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" SSANPPMDQNSPEDLFTLGSYLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR021280 (49.4%) IPR052724 (49.4%) IPR011990 (1.2%)" "Protein O-mannosyl-transferase TMEM260-like (49.4%) Glycosyltransferase 117 domain-containing protein (49.4%) Tetratricopeptide-like helical domain superfamily (1.2%)" QANEDKNELSFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (18.3%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (18.3%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" RPVELEFACNLNNDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR002192 (33.3%) IPR051549 (33.3%) IPR013815 (30.8%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (33.3%) Phosphoenolpyruvate Utilizing Enzyme (33.3%) ATP-grasp fold, subdomain 1 (30.8%)" TSALVLTHYER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (29.8%) IPR010230 (29.8%) IPR027417 (29.8%)" "ABC transporter-like, ATP-binding domain (29.8%) FeS cluster assembly SUF system, ATPase SufC (29.8%) P-loop containing nucleoside triphosphate hydrolase (29.8%)" MMNATQWLDYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" LYYDGELK root "1.4.1.13 (98.1%) 3.6.4.13 (0.6%) 1.4.1.14 (0.3%)" "glutamate synthase (NADPH) (98.1%) RNA helicase (0.6%) glutamate synthase (NADH) (0.3%)" "GO:0006537 (19%) GO:0019676 (18.9%) GO:0005975 (0.3%)" "GO:0000932 (0.1%) GO:0005634 (0.1%) GO:0005829 (0.1%)" "GO:0051538 (19%) GO:0046872 (18.9%) GO:0015930 (9.5%)" "glutamate biosynthetic process (19%) ammonia assimilation cycle (18.9%) carbohydrate metabolic process (0.3%)" "P-body (0.1%) nucleus (0.1%) cytosol (0.1%)" "3 iron, 4 sulfur cluster binding (19%) metal ion binding (18.9%) glutamate synthase activity (9.5%)" "IPR006982 (12.2%) IPR017932 (12.1%) IPR050711 (12.1%)" "Glutamate synthase, central-N (12.2%) Glutamine amidotransferase type 2 domain (12.1%) Electron transfer and nitrogen metabolism enzyme (12.1%)" QALLDMGGSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) LSSYNDMYMGYVQGAGSNPWTGSLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TYTMPVTASWMVDLFGNLLSQKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" VYHALTHADGFYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR012547 (38.1%) IPR018631 (38.1%) IPR027417 (23.7%)" "PD-(D/E)XK nuclease superfamily 9 (38.1%) AAA-ATPase-like domain (38.1%) P-loop containing nucleoside triphosphate hydrolase (23.7%)" QYVQQLLDNDKAYLAFDTPEELEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004818 (16.7%) GO:0005524 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR000924 (10%) IPR001412 (10%) IPR004527 (10%)" "Glutamyl/glutaminyl-tRNA synthetase (10%) Aminoacyl-tRNA synthetase, class I, conserved site (10%) Glutamate-tRNA ligase, bacterial/mitochondrial (10%)" LLLPEYGR root "1.1.1.- (50%) 2.1.2.9 (50%)" "With NAD(+) or NADP(+) as acceptor (50%) methionyl-tRNA formyltransferase (50%)" "GO:0006310 (2.6%) GO:0006887 (2.6%) GO:0015031 (2.6%)" "GO:0000145 (2.6%) GO:0005759 (2.6%) GO:0000932 (1.3%)" "GO:0016740 (42.1%) GO:0003677 (3.9%) GO:0005524 (3.9%)" "DNA recombination (2.6%) exocytosis (2.6%) protein transport (2.6%)" "exocyst (2.6%) mitochondrial matrix (2.6%) P-body (1.3%)" "transferase activity (42.1%) DNA binding (3.9%) ATP binding (3.9%)" "IPR025632 (89.1%) IPR010043 (0.5%) IPR027417 (0.5%)" "Protein of unknown function DUF4290 (89.1%) Bifunctional uridylyltransferase/uridylyl-removing enzyme (0.5%) P-loop containing nucleoside triphosphate hydrolase (0.5%)" DGDLLVLDLPSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (16.8%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (16.8%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (16.9%) IPR020558 (16.9%) IPR056740 (16.9%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (16.9%)" YSTYAFTEQGVAMLSSVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR018873 (100%) KilA-N, DNA-binding domain (100%) DWTDATLK root 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (18.4%) GO:0033499 (18.4%) GO:0006405 (1.9%)" "GO:0005737 (18.4%) GO:0044611 (1.9%)" "GO:0004034 (18.4%) GO:0030246 (17.1%) GO:0017056 (1.9%)" "glucose metabolic process (18.4%) galactose catabolic process via UDP-galactose, Leloir pathway (18.4%) RNA export from nucleus (1.9%)" "cytoplasm (18.4%) nuclear pore inner ring (1.9%)" "aldose 1-epimerase activity (18.4%) carbohydrate binding (17.1%) structural constituent of nuclear pore (1.9%)" "IPR008183 (16.6%) IPR018052 (16.6%) IPR047215 (16.6%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (16.6%) Aldose 1-epimerase, conserved site (16.6%) Galactose mutarotase-like (16.6%)" YTEAMQGPNLEMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (13.1%) GO:0015966 (12.1%)" "GO:0005737 (13.1%) GO:0070062 (12.1%) GO:1990742 (12.1%)" "GO:0004820 (13.1%) GO:0004081 (12.1%) GO:0005524 (12.1%)" "glycyl-tRNA aminoacylation (13.1%) diadenosine tetraphosphate biosynthetic process (12.1%)" "cytoplasm (13.1%) extracellular exosome (12.1%) microvesicle (12.1%)" "glycine-tRNA ligase activity (13.1%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.1%) ATP binding (12.1%)" "IPR027031 (12%) IPR002314 (11.1%) IPR002315 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (12%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Glycyl-tRNA synthetase (11.1%)" SLTTLVSNVFKPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (50%) GO:0016881 (50%) cytoplasm (50%) acid-amino acid ligase activity (50%) "IPR004993 (34.8%) IPR055377 (32.6%) IPR055378 (32.6%)" "GH3 family (34.8%) GH3, middle domain (32.6%) GH3, C-terminal domain (32.6%)" ASGHCAEFLNFDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.11.9 (100%) Xaa-Pro aminopeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0030145 (25%) GO:0070006 (25%)" proteolysis (25%) cytosol (25%) "manganese ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000994 (20.2%) IPR007865 (20.2%) IPR052433 (20.2%)" "Peptidase M24 (20.2%) Aminopeptidase P, N-terminal (20.2%) Xaa-Pro dipeptidase-like (20.2%)" YQLLPDKGNLSAEQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011204 (100%) Virulence protein RhuM-like (100%) RNFLETATR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (77.6%) 6.3.4.16 (22.4%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (77.6%) carbamoyl-phosphate synthase (ammonia) (22.4%)" "GO:0006541 (14.2%) GO:0006526 (11.5%) GO:0006221 (11.5%)" GO:0005737 (14.2%) "GO:0004088 (14.2%) GO:0005524 (14.2%) GO:0046872 (14.1%)" "glutamine metabolic process (14.2%) L-arginine biosynthetic process (11.5%) pyrimidine nucleotide biosynthetic process (11.5%)" cytoplasm (14.2%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.2%) ATP binding (14.2%) metal ion binding (14.1%)" "IPR011607 (10.2%) IPR005479 (10.1%) IPR011761 (10.1%)" "Methylglyoxal synthase-like domain (10.2%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%)" DWVEDSEERDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GDKVLVFK root 2.7.7.27 (100%) glucose-1-phosphate adenylyltransferase (100%) "GO:0006412 (15.8%) GO:0006353 (2.7%) GO:0006281 (0.7%)" "GO:0005840 (15.9%) GO:0005737 (15.8%) GO:1990904 (15.8%)" "GO:0003735 (15.8%) GO:0019843 (15.8%) GO:0003677 (0.7%)" "translation (15.8%) DNA-templated transcription termination (2.7%) DNA repair (0.7%)" "ribosome (15.9%) cytoplasm (15.8%) ribonucleoprotein complex (15.8%)" "structural constituent of ribosome (15.8%) rRNA binding (15.8%) DNA binding (0.7%)" "IPR028909 (22.5%) IPR036164 (22.5%) IPR001787 (22.5%)" "Large ribosomal subunit protein bL21-like (22.5%) Large ribosomal subunit protein bL21-like superfamily (22.5%) Large ribosomal subunit protein bL21 (22.5%)" LVFLPSNLCYDFSTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (17%) IPR004602 (17%) IPR041102 (17%)" "ABC transporter-like, ATP-binding domain (17%) UvrABC system subunit A (17%) UvrA, interaction domain (17%)" RLPLTTGAR root GO:0009451 (7.7%) GO:0009279 (84.6%) GO:0003723 (7.7%) RNA modification (7.7%) cell outer membrane (84.6%) RNA binding (7.7%) "IPR011990 (31.4%) IPR012944 (31.4%) IPR033985 (28.6%)" "Tetratricopeptide-like helical domain superfamily (31.4%) RagB/SusD domain (31.4%) SusD-like, N-terminal (28.6%)" TLEDNKQLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" DFKELLLHFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013785 (50%) IPR036206 (50%)" "Aldolase-type TIM barrel (50%) Thiamin phosphate synthase superfamily (50%)" ESLSATHNGWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.45 (100%) 2-dehydro-3-deoxygluconokinase (100%) "GO:0016301 (95.2%) GO:0008673 (4.8%)" "kinase activity (95.2%) 2-dehydro-3-deoxygluconokinase activity (4.8%)" "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" GVSAAKEDVHNALK root 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.5%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.5%)" "IPR036921 (20.2%) IPR004733 (20%) IPR016188 (20%)" "PurM-like, N-terminal domain superfamily (20.2%) Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, N-terminal domain (20%)" VGTLLAEAGGFVSAPLYSSVSGTVFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.-.-.- (100%) Translocases (100%) GO:0022900 (19.9%) GO:0005886 (19.9%) "GO:0009055 (19.9%) GO:0046872 (19.9%) GO:0051539 (19.9%)" electron transport chain (19.9%) plasma membrane (19.9%) "electron transfer activity (19.9%) metal ion binding (19.9%) 4 iron, 4 sulfur cluster binding (19.9%)" "IPR010208 (14.4%) IPR011538 (14.4%) IPR017896 (14.4%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.4%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" LLFSSAFR root "3.1.5.1 (96.7%) 2.7.11.1 (1.6%) 6.1.1.14 (1.6%)" "dGTPase (96.7%) non-specific serine/threonine protein kinase (1.6%) glycine--tRNA ligase (1.6%)" "GO:0006203 (47.2%) GO:0006783 (0.3%) GO:0016226 (0.3%)" "GO:0016020 (0.8%) GO:0005759 (0.3%) GO:0005886 (0.3%)" "GO:0008832 (47.2%) GO:0016740 (0.4%) GO:0016793 (0.4%)" "dGTP catabolic process (47.2%) heme biosynthetic process (0.3%) iron-sulfur cluster assembly (0.3%)" "membrane (0.8%) mitochondrial matrix (0.3%) plasma membrane (0.3%)" "dGTPase activity (47.2%) transferase activity (0.4%) triphosphoric monoester hydrolase activity (0.4%)" "IPR006261 (15.4%) IPR003607 (15.3%) IPR050135 (15.2%)" "dGTP triphosphohydrolase (15.4%) HD/PDEase domain (15.3%) Deoxyguanosinetriphosphate triphosphohydrolase-like (15.2%)" YAELGGAYQDEKNECGLSGQYAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0008643 (33.3%) GO:0016020 (33.3%) GO:0015288 (33.3%) carbohydrate transport (33.3%) membrane (33.3%) porin activity (33.3%) "IPR007049 (50%) IPR038673 (50%)" "Carbohydrate-selective porin OprB (50%) Carbohydrate-selective porin OprB superfamily (50%)" YLPNVLEYSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001173 (51.8%) IPR029044 (48.2%)" "Glycosyltransferase 2-like (51.8%) Nucleotide-diphospho-sugar transferases (48.2%)" LGSSVEFDWCGVQALNTLR Pseudomonadati Bacteria Pseudomonadati "6.3.5.5 (94.5%) 6.3.4.16 (5.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (94.5%) carbamoyl-phosphate synthase (ammonia) (5.5%)" "GO:0006541 (14.1%) GO:0006221 (11%) GO:0006526 (10.9%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (11%) L-arginine biosynthetic process (10.9%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.2%) IPR011761 (10.2%) IPR005480 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.2%) ATP-grasp fold (10.2%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%)" LDDTQQVVSGTPMNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025380 (100%) Domain of unknown function DUF4369 (100%) DYEDTYLADQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VETLSVGNTNLGGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" AADYHLMVNAHEAVRPTGLCR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0030246 (50.8%) GO:0016787 (49.2%)" "carbohydrate binding (50.8%) hydrolase activity (49.2%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" NPSLFNPVR Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.4.-.- (46.7%) 2.4.1.- (40%) 2.4.2.- (6.7%)" "Acting on peptide bonds (peptidases) (46.7%) Hexosyltransferases (40%) Pentosyltransferases (6.7%)" "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (11.1%) GO:0016020 (0.1%)" "GO:0008955 (11.2%) GO:0008658 (11.1%) GO:0004180 (10.9%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (11.1%) membrane (0.1%)" "peptidoglycan glycosyltransferase activity (11.2%) penicillin binding (11.1%) carboxypeptidase activity (10.9%)" "IPR001264 (16.8%) IPR050396 (16.8%) IPR001460 (16.6%)" "Glycosyl transferase, family 51 (16.8%) Glycosyltransferase 51/Transpeptidase (16.8%) Penicillin-binding protein, transpeptidase (16.6%)" LDVTDYDWLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.5 (100%) 5'-nucleotidase (100%) GO:0005737 (23.6%) "GO:0000166 (23.6%) GO:0008253 (23.6%) GO:0046872 (23.6%)" cytoplasm (23.6%) "nucleotide binding (23.6%) 5'-nucleotidase activity (23.6%) metal ion binding (23.6%)" "IPR002828 (34.2%) IPR030048 (34.2%) IPR036523 (31.5%)" "Survival protein SurE-like phosphatase/nucleotidase (34.2%) Survival protein SurE (34.2%) SurE-like phosphatase/nucleotidase superfamily (31.5%)" VSATGQLYGSVNAATVAEELAKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.3%) IPR009027 (14.3%) IPR020069 (14.3%)" "Large ribosomal subunit protein bL9 (14.3%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.3%) Large ribosomal subunit protein bL9, C-terminal (14.3%)" GLDVYLEAMNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) RFNLGVK root "2.7.7.60 (31.8%) 4.6.1.12 (31.8%) 1.14.14.1 (9.1%)" "2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (31.8%) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (31.8%) unspecific monooxygenase (9.1%)" "GO:0006357 (7%) GO:0031175 (6.6%) GO:0048667 (6.6%)" "GO:0009279 (9.9%) GO:0000785 (6.6%) GO:0035189 (6.6%)" "GO:0000977 (6.8%) GO:0046872 (1.6%) GO:0008685 (1.1%)" "regulation of transcription by RNA polymerase II (7%) neuron projection development (6.6%) cell morphogenesis involved in neuron differentiation (6.6%)" "cell outer membrane (9.9%) chromatin (6.6%) Rb-E2F complex (6.6%)" "RNA polymerase II transcription regulatory region sequence-specific DNA binding (6.8%) metal ion binding (1.6%) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity (1.1%)" "IPR012910 (6.5%) IPR037066 (6.3%) IPR036942 (5.9%)" "TonB-dependent receptor, plug domain (6.5%) TonB-dependent receptor, plug domain superfamily (6.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (5.9%)" RVVLVGGGLGGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.9 (97.6%) 1.6.5.- (2.4%)" "NADH:ubiquinone reductase (non-electrogenic) (97.6%) With a quinone or similar compound as acceptor (2.4%)" "GO:0003954 (97.6%) GO:0050136 (2.4%)" "NADH dehydrogenase activity (97.6%) NADH dehydrogenase (quinone) (non-electrogenic) activity (2.4%)" "IPR023753 (25.3%) IPR045024 (25.3%) IPR054585 (25.3%)" "FAD/NAD(P)-binding domain (25.3%) Alternative NADH dehydrogenase (25.3%) External alternative NADH-ubiquinone oxidoreductase-like, C-terminal domain (25.3%)" YGDNFQAVLMSNAVQEMHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.94 (100%) glycerol-3-phosphate dehydrogenase [NAD(P)(+)] (100%) "GO:0005975 (16.7%) GO:0008654 (16.7%) GO:0046168 (16.7%)" GO:0005829 (16.7%) "GO:0051287 (16.7%) GO:0047952 (14%) GO:0141153 (2.6%)" "carbohydrate metabolic process (16.7%) phospholipid biosynthetic process (16.7%) glycerol-3-phosphate catabolic process (16.7%)" cytosol (16.7%) "NAD binding (16.7%) glycerol-3-phosphate dehydrogenase [NAD(P)+] activity (14%) glycerol-3-phosphate dehydrogenase (NADP+) activity (2.6%)" "IPR006109 (17.1%) IPR006168 (17.1%) IPR011128 (17.1%)" "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal (17.1%) Glycerol-3-phosphate dehydrogenase, NAD-dependent (17.1%) Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal (17.1%)" LNLADKGVLNVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) TVTLQQVPLSWLSFVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032293 (100%) Protein of unknown function DUF4840 (100%) SNVVFTDSYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae DLLTGWLK root "3.2.1.21 (95.8%) 5.6.2.4 (4.2%)" "beta-glucosidase (95.8%) DNA 3'-5' helicase (4.2%)" "GO:0009251 (38.3%) GO:0000725 (1.7%) GO:0043041 (1.7%)" "GO:0016020 (5%) GO:0005829 (1.7%)" "GO:0008422 (38.3%) GO:0003677 (1.7%) GO:0005524 (1.7%)" "glucan catabolic process (38.3%) recombinational repair (1.7%) amino acid activation for nonribosomal peptide biosynthetic process (1.7%)" "membrane (5%) cytosol (1.7%)" "beta-glucosidase activity (38.3%) DNA binding (1.7%) ATP binding (1.7%)" "IPR001764 (11.7%) IPR002772 (11.7%) IPR026891 (11.7%)" "Glycoside hydrolase, family 3, N-terminal (11.7%) Glycoside hydrolase family 3 C-terminal domain (11.7%) Fibronectin type III-like domain (11.7%)" GEPGTGDVVQAVTHMRMMQSELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (23.6%) GO:0016843 (1.4%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (23.6%) amine-lyase activity (1.4%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" EQLPEVPAER Bacteria Bacteria 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (41.7%) "GO:0004475 (41.7%) GO:0005525 (14.6%) GO:0016853 (2.1%)" GDP-mannose biosynthetic process (41.7%) "mannose-1-phosphate guanylyltransferase (GTP) activity (41.7%) GTP binding (14.6%) isomerase activity (2.1%)" "IPR005835 (25.3%) IPR049577 (25.3%) IPR051161 (25.3%)" "Nucleotidyl transferase domain (25.3%) GDP-mannose pyrophosphorylase, N-terminal domain (25.3%) Mannose-6-phosphate isomerase type 2 (25.3%)" TALPQALEWLMEQGYEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (37.5%) GO:0016020 (31.3%) GO:0016810 (31.3%) carbohydrate metabolic process (37.5%) membrane (31.3%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (31.3%) "IPR011330 (37.5%) IPR002509 (31.3%) IPR050248 (31.3%)" "Glycoside hydrolase/deacetylase, beta/alpha-barrel (37.5%) NodB homology domain (31.3%) Polysaccharide deacetylase, ArnD subfamily (31.3%)" SGSYESTLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR002765 (52.6%) IPR035439 (47.4%)" "Uncharacterised protein family UPF0145, YbjQ-like (52.6%) UPF0145 domain superfamily (47.4%)" VLVNGLLPDEVGFFNDVLSKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (17%) GO:0000428 (17%) "GO:0003677 (17%) GO:0003899 (17%) GO:0000287 (16%)" DNA-templated transcription (17%) DNA-directed RNA polymerase complex (17%) "DNA binding (17%) DNA-directed RNA polymerase activity (17%) magnesium ion binding (16%)" "IPR007081 (9.5%) IPR007083 (9.5%) IPR038120 (9.5%)" "RNA polymerase Rpb1, domain 5 (9.5%) RNA polymerase Rpb1, domain 4 (9.5%) RNA polymerase Rpb1, funnel domain superfamily (9.5%)" FDFGFAAR Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) IPR014914 (100%) RES domain (100%) VAWVHYSGLEGDEYHALAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (20%) IPR006235 (20%) IPR015421 (20%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (20%) O-acetylhomoserine/O-acetylserine sulfhydrylase (20%) Pyridoxal phosphate-dependent transferase, major domain (20%)" GYNYEDAVVLSER Bacteria Bacteria 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (9.1%) IPR015712 (9.1%) IPR019462 (9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (9.1%) DNA-directed RNA polymerase, subunit 2 (9.1%) DNA-directed RNA polymerase, beta subunit, external 1 domain (9%)" YENDQFSGNAYLDLKPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" FPDGASGTQLDAVGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (24.5%) GO:0005737 (25.2%) "GO:0046872 (25.2%) GO:0070006 (25.2%)" proteolysis (24.5%) cytoplasm (25.2%) "metal ion binding (25.2%) metalloaminopeptidase activity (25.2%)" "IPR000994 (13.1%) IPR050422 (13.1%) IPR000587 (12.5%)" "Peptidase M24 (13.1%) Xaa-Pro aminopeptidase P (13.1%) Creatinase, N-terminal (12.5%)" LATGSQSCLALPSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015679 (19.1%) GO:0060003 (19.1%)" "GO:0016020 (19.1%) GO:0030313 (19.1%) GO:1990281 (2.2%)" "GO:0022857 (19.1%) GO:0015562 (2.2%)" "plasma membrane copper ion transport (19.1%) copper ion export (19.1%)" "membrane (19.1%) cell envelope (19.1%) efflux pump complex (2.2%)" "transmembrane transporter activity (19.1%) efflux transmembrane transporter activity (2.2%)" "IPR032317 (35%) IPR006143 (32.5%) IPR051909 (32.5%)" "Unknown (35%) RND efflux pump, membrane fusion protein (32.5%) Membrane Fusion Protein Cation Efflux System (32.5%)" EEGLERDNEAAGYWAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" TYHVDLFVDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.80 (66.7%) 3.2.1.65 (33.3%)" "fructan beta-fructosidase (66.7%) levanase (33.3%)" GO:0005987 (32.8%) GO:0005737 (32.8%) "GO:0004575 (32.8%) GO:0051669 (1.1%) GO:0031219 (0.5%)" sucrose catabolic process (32.8%) cytoplasm (32.8%) "sucrose alpha-glucosidase activity (32.8%) fructan beta-fructosidase activity (1.1%) levanase activity (0.5%)" "IPR013189 (15%) IPR013320 (14.5%) IPR001362 (14.2%)" "Glycosyl hydrolase family 32, C-terminal (15%) Concanavalin A-like lectin/glucanase domain superfamily (14.5%) Glycoside hydrolase, family 32 (14.2%)" AAAEELGLK root "2.1.1.192 (31.3%) 3.4.11.4 (25%) 4.2.1.47 (18.8%)" "23S rRNA (adenine(2503)-C(2))-methyltransferase (31.3%) tripeptide aminopeptidase (25%) GDP-mannose 4,6-dehydratase (18.8%)" "GO:0005975 (17.6%) GO:0006508 (2.5%) GO:0030488 (2.5%)" "GO:0005737 (3.1%) GO:0005886 (1.3%) GO:0005743 (0.6%)" "GO:0016301 (17.6%) GO:0016616 (4.4%) GO:0051287 (4.4%)" "carbohydrate metabolic process (17.6%) proteolysis (2.5%) tRNA methylation (2.5%)" "cytoplasm (3.1%) plasma membrane (1.3%) mitochondrial inner membrane (0.6%)" "kinase activity (17.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (4.4%) NAD binding (4.4%)" "IPR018484 (11.5%) IPR018485 (11.5%) IPR043129 (11.5%)" "Carbohydrate kinase FGGY, N-terminal (11.5%) Carbohydrate kinase FGGY, C-terminal (11.5%) ATPase, nucleotide binding domain (11.5%)" MLLTGDLTQLDLPR Bacteria Bacteria GO:0005829 (46.3%) "GO:0005524 (46.3%) GO:0003723 (7.3%)" cytosol (46.3%) "ATP binding (46.3%) RNA binding (7.3%)" "IPR003714 (31.7%) IPR027417 (31.7%) IPR051451 (31.7%)" "PhoH-like protein (31.7%) P-loop containing nucleoside triphosphate hydrolase (31.7%) PhoH2-like (31.7%)" AHCFFHQVEGLYVDK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.5%) "GO:0005737 (16.5%) GO:0016020 (0.9%)" "GO:0000049 (16.5%) GO:0004826 (16.5%) GO:0005524 (16.5%)" phenylalanyl-tRNA aminoacylation (16.5%) "cytoplasm (16.5%) membrane (0.9%)" "tRNA binding (16.5%) phenylalanine-tRNA ligase activity (16.5%) ATP binding (16.5%)" "IPR002319 (14.3%) IPR004188 (14.3%) IPR004529 (14.3%)" "Phenylalanyl-tRNA synthetase (14.3%) Phenylalanine-tRNA ligase, class II, N-terminal (14.3%) Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (14.3%)" MEQSSFLK root "4.2.1.42 (50%) 4.2.1.7 (50%)" "galactarate dehydratase (50%) altronate dehydratase (50%)" "GO:0019698 (43.1%) GO:0015679 (2.8%) GO:0060003 (2.8%)" "GO:0016020 (2.8%) GO:0030313 (2.8%)" "GO:0016829 (41.7%) GO:0022857 (2.8%) GO:0008789 (1.4%)" "D-galacturonate catabolic process (43.1%) plasma membrane copper ion transport (2.8%) copper ion export (2.8%)" "membrane (2.8%) cell envelope (2.8%)" "lyase activity (41.7%) transmembrane transporter activity (2.8%) altronate dehydratase activity (1.4%)" "IPR007392 (19.4%) IPR013974 (19.4%) IPR044144 (19.4%)" "D-galactarate/Altronate dehydratase, second domain (19.4%) SAF domain (19.4%) UxaA/GarD, SAF domain (19.4%)" PQDFFACNAPLK Bacteria Bacteria 5.3.1.25 (100%) L-fucose isomerase (100%) "GO:0006004 (30.9%) GO:0005996 (2.4%)" GO:0005737 (33.3%) "GO:0008736 (30.9%) GO:0016861 (2.4%)" "fucose metabolic process (30.9%) monosaccharide metabolic process (2.4%)" cytoplasm (33.3%) "L-fucose isomerase activity (30.9%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (2.4%)" "IPR009015 (51.4%) IPR015888 (48.6%)" "L-fucose isomerase, N-terminal/central domain superfamily (51.4%) L-fucose isomerase, C-terminal (48.6%)" NYLMEVAAPGLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (35.7%) IPR031107 (35.7%) IPR008978 (28.6%)" "Alpha crystallin/Hsp20 domain (35.7%) Small heat shock protein (35.7%) HSP20-like chaperone (28.6%)" TFEEVADELTNVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002912 (25%) IPR022986 (25%) IPR045865 (25%)" "ACT domain (25%) Uncharacterised protein family UPF0237, ACT-type (25%) ACT-like domain (25%)" NLLFLCGGAFDGLER Bacteria Bacteria "GO:0051301 (10.1%) GO:0051603 (10.1%)" GO:0009376 (10.1%) "GO:0005524 (10.1%) GO:0016887 (10.1%) GO:0051082 (10.1%)" "cell division (10.1%) proteolysis involved in protein catabolic process (10.1%)" HslUV protease complex (10.1%) "ATP binding (10.1%) ATP hydrolysis activity (10.1%) unfolded protein binding (10.1%)" "IPR003959 (10.8%) IPR050052 (10.8%) IPR004487 (10.8%)" "ATPase, AAA-type, core (10.8%) ATP-dependent Clp protease ATP-binding subunit ClpX (10.8%) Clp protease, ATP-binding subunit ClpX (10.8%)" LSDLYLLYAEALLQADGNNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR012944 (34.4%) IPR033985 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) RagB/SusD domain (34.4%) SusD-like, N-terminal (31.3%)" ALEAYPGR root "2.6.1.1 (66.7%) 2.6.1.- (24.1%) 5.3.1.16 (5.6%)" "aspartate transaminase (66.7%) Transaminases (24.1%) 1-(5-phosphoribosyl)-5[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamidisomerase (5.6%)" "GO:0006520 (30.5%) GO:0000105 (0.4%) GO:0000162 (0.4%)" "GO:0032993 (0.6%) GO:0005737 (0.4%) GO:0016020 (0.4%)" "GO:0030170 (30.5%) GO:0008483 (25.9%) GO:0004069 (4.9%)" "amino acid metabolic process (30.5%) L-histidine biosynthetic process (0.4%) L-tryptophan biosynthetic process (0.4%)" "protein-DNA complex (0.6%) cytoplasm (0.4%) membrane (0.4%)" "pyridoxal phosphate binding (30.5%) transaminase activity (25.9%) L-aspartate:2-oxoglutarate aminotransferase activity (4.9%)" "IPR004839 (18.8%) IPR015422 (18.8%) IPR050596 (18.8%)" "Aminotransferase, class I/classII, large domain (18.8%) Pyridoxal phosphate-dependent transferase, small domain (18.8%) Aspartate/prephenate aminotransferase-like (18.8%)" YGSEHFPTQTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR023996 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" VRPLSWPLGQGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006449 (16.7%) GO:0005829 (16.7%) "GO:0003924 (16.7%) GO:0005525 (16.7%) GO:0016149 (16.7%)" regulation of translational termination (16.7%) cytosol (16.7%) "GTPase activity (16.7%) GTP binding (16.7%) translation release factor activity, codon specific (16.7%)" "IPR000795 (9.2%) IPR004548 (9.2%) IPR005225 (9.2%)" "Translational (tr)-type GTP-binding domain (9.2%) Peptide chain release factor 3 (9.2%) Small GTP-binding domain (9.2%)" YFNLALGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046813 (50%) GO:0009279 (50%) receptor-mediated virion attachment to host cell (50%) cell outer membrane (50%) "IPR011990 (33.3%) IPR019734 (33.3%) IPR050498 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) Tetratricopeptide repeat (33.3%) Photosystem I assembly protein Ycf3 (33.3%)" LAGTLVPVFSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.3%) IPR003385 (20.3%) IPR013783 (19.8%)" "Carbohydrate binding module family 20 (20.3%) Glycoside hydrolase, family 77 (20.3%) Immunoglobulin-like fold (19.8%)" TTETKDVYPMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" YALSAYGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (48.5%) "GO:0004650 (48.5%) GO:0004557 (3%)" carbohydrate metabolic process (48.5%) "polygalacturonase activity (48.5%) alpha-galactosidase activity (3%)" "IPR000743 (12.9%) IPR006626 (12.9%) IPR010905 (12.9%)" "Glycoside hydrolase, family 28 (12.9%) Parallel beta-helix repeat (12.9%) Glycosyl hydrolase, family 88 (12.9%)" QVNDKELFVLPDLTTEMSELEAR Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" DLLQPTLAVLTNLGAAHQENFSSMEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.7%) "GO:0005524 (20.5%) GO:0016881 (20.5%) GO:0008784 (19.7%)" D-alanine biosynthetic process (19.7%) "ATP binding (20.5%) acid-amino acid ligase activity (20.5%) alanine racemase activity (19.7%)" "IPR013221 (10.4%) IPR051046 (10.4%) IPR000821 (10%)" "Mur ligase, central (10.4%) MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.4%) Alanine racemase (10%)" HFFTPENVMDTER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.29 (100%) tRNA-guanosine(34) preQ1 transglycosylase (100%) GO:0002099 (33.3%) GO:0005829 (33.3%) GO:0008479 (33.3%) tRNA wobble guanine modification (33.3%) cytosol (33.3%) tRNA-guanosine(34) queuine transglycosylase activity (33.3%) "IPR002616 (25%) IPR004803 (25%) IPR036511 (25%)" "tRNA-guanine(15) transglycosylase-like (25%) tRNA-guanine transglycosylase (25%) Queuine tRNA-ribosyltransferase-like (25%)" MEDYDQLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016747 (63.3%) GO:0016787 (36.7%)" "acyltransferase activity, transferring groups other than amino-acyl groups (63.3%) hydrolase activity (36.7%)" "IPR000182 (20.4%) IPR001110 (20.4%) IPR003010 (20.4%)" "GNAT domain (20.4%) Uncharacterised protein family UPF0012, conserved site (20.4%) Carbon-nitrogen hydrolase (20.4%)" EYLESYGMK root 4.2.1.8 (100%) mannonate dehydratase (100%) GO:0042840 (24.1%) GO:0005737 (1.1%) "GO:0008198 (24.1%) GO:0008927 (24.1%) GO:0030145 (24.1%)" D-glucuronate catabolic process (24.1%) cytoplasm (1.1%) "ferrous iron binding (24.1%) mannonate dehydratase activity (24.1%) manganese ion binding (24.1%)" "IPR036237 (45.8%) IPR004628 (43.8%) IPR012675 (2.1%)" "Xylose isomerase-like superfamily (45.8%) Mannonate dehydratase (43.8%) Beta-grasp domain superfamily (2.1%)" TWVAPEDAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.7%) IPR012944 (32.1%) IPR033985 (32.1%)" "Tetratricopeptide-like helical domain superfamily (35.7%) RagB/SusD domain (32.1%) SusD-like, N-terminal (32.1%)" FFGSVSLEENALDVPTLAEGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR005077 (100%) Peptidase C11, clostripain (100%) LANQQGVELHALVAGTGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (17%) IPR014729 (17%) IPR014730 (17%)" "Electron transfer flavoprotein alpha subunit/FixB (17%) Rossmann-like alpha/beta/alpha sandwich fold (17%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (17%)" FKDLLSPNLQGALGYQFSPVFGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (33.3%) IPR036737 (33.3%) IPR050330 (33.3%)" "OmpA-like domain (33.3%) OmpA-like domain superfamily (33.3%) Bacterial Outer Membrane Structural/Functional (33.3%)" LDMANPNMHFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.18 (100%) glutamine--tRNA ligase (100%) "GO:0006425 (24.8%) GO:0006424 (0.7%)" GO:0005829 (24.8%) "GO:0004819 (24.8%) GO:0005524 (24.8%)" "glutaminyl-tRNA aminoacylation (24.8%) glutamyl-tRNA aminoacylation (0.7%)" cytosol (24.8%) "glutamine-tRNA ligase activity (24.8%) ATP binding (24.8%)" "IPR020058 (10.5%) IPR050132 (10.5%) IPR004514 (10.4%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.5%) Glutamine/Glutamate--tRNA Ligase (10.5%) Glutamine-tRNA synthetase (10.4%)" MLENDQYYQGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) EQPGTYYLGFNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR005151 (50%) IPR029045 (50%)" "Tail specific protease (50%) ClpP/crotonase-like domain superfamily (50%)" HESEAYWEELEEGAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25%) IPR010982 (25%) IPR025997 (25%)" "LacI-type HTH domain (25%) Lambda repressor-like, DNA-binding domain superfamily (25%) Periplasmic binding protein (25%)" KVENAVENLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20%) GO:0019676 (20%)" "GO:0046872 (20%) GO:0051538 (20%) GO:0015930 (14%)" "glutamate biosynthetic process (20%) ammonia assimilation cycle (20%)" "metal ion binding (20%) 3 iron, 4 sulfur cluster binding (20%) glutamate synthase activity (14%)" "IPR002489 (12.5%) IPR002932 (12.5%) IPR006982 (12.5%)" "Glutamate synthase, alpha subunit, C-terminal (12.5%) Glutamate synthase domain (12.5%) Glutamate synthase, central-N (12.5%)" DHTNPGVFHPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.9%) IPR003385 (20.9%) IPR013783 (19.4%)" "Carbohydrate binding module family 20 (20.9%) Glycoside hydrolase, family 77 (20.9%) Immunoglobulin-like fold (19.4%)" SRYEMTFANNLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) AMTGSSVVDLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0000160 (0.5%) GO:0016020 (18.6%) "GO:0003700 (20.6%) GO:0043565 (20.6%) GO:0000155 (20.1%)" phosphorelay signal transduction system (0.5%) membrane (18.6%) "DNA-binding transcription factor activity (20.6%) sequence-specific DNA binding (20.6%) phosphorelay sensor kinase activity (20.1%)" "IPR001789 (8%) IPR018060 (8%) IPR009057 (7.8%)" "Signal transduction response regulator, receiver domain (8%) AraC-like, DNA binding HTH domain (8%) Homedomain-like superfamily (7.8%)" ALGSLDDMLVNFLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR041685 (33.9%) IPR051396 (33.9%) IPR027417 (32.2%)" "Endonuclease GajA/Old nuclease/RecF-like, AAA domain (33.9%) Bacterial Antiviral Defense Nuclease (33.9%) P-loop containing nucleoside triphosphate hydrolase (32.2%)" VLEVLDDK root "2.7.1.40 (40%) 2.4.1.1 (10%) 1.17.7.4 (5%)" "pyruvate kinase (40%) glycogen phosphorylase (10%) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (5%)" "GO:0007266 (7.1%) GO:0035023 (7.1%) GO:1900029 (7.1%)" "GO:0032587 (7.8%) GO:0005737 (7.1%) GO:0031982 (6.9%)" "GO:0003779 (7.8%) GO:0005524 (3.3%) GO:0016301 (2.9%)" "Rho protein signal transduction (7.1%) regulation of Rho protein signal transduction (7.1%) positive regulation of ruffle assembly (7.1%)" "ruffle membrane (7.8%) cytoplasm (7.1%) vesicle (6.9%)" "actin binding (7.8%) ATP binding (3.3%) kinase activity (2.9%)" "IPR001452 (6.6%) IPR036028 (6.6%) IPR013761 (6.4%)" "SH3 domain (6.6%) SH3-like domain superfamily (6.6%) Sterile alpha motif/pointed domain superfamily (6.4%)" ELGNYDPTYLTR Pseudomonadati Bacteria Pseudomonadati GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (31.7%) GO:0051536 (1.6%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (31.7%) iron-sulfur cluster binding (1.6%)" "IPR003741 (14.4%) IPR004452 (14.4%) IPR017896 (14.4%)" "LUD domain (14.4%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" TLLMLFFNNSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.11 (100%) N-succinylornithine carbamoyltransferase (100%) "GO:0019240 (25%) GO:0042450 (25%)" "GO:0004585 (25%) GO:0016597 (25%)" "citrulline biosynthetic process (25%) L-arginine biosynthetic process via ornithine (25%)" "ornithine carbamoyltransferase activity (25%) amino acid binding (25%)" "IPR006131 (20.2%) IPR006132 (20.2%) IPR043696 (20.2%)" "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.2%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20.2%) N-succinylornithine carbamoyltransferase ArgF'-like (20.2%)" ELGVLDLLVNNAGLLK Bacteria Bacteria "1.1.1.69 (96%) 1.1.1.125 (4%)" "gluconate 5-dehydrogenase (96%) 2-deoxy-D-gluconate 3-dehydrogenase (4%)" GO:0008206 (23.5%) "GO:0008874 (41.2%) GO:0016491 (17.6%) GO:0016616 (14.7%)" bile acid metabolic process (23.5%) "gluconate 5-dehydrogenase activity (41.2%) oxidoreductase activity (17.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (14.7%)" "IPR002347 (31.6%) IPR020904 (31.6%) IPR036291 (31.6%)" "Short-chain dehydrogenase/reductase SDR (31.6%) Short-chain dehydrogenase/reductase, conserved site (31.6%) NAD(P)-binding domain superfamily (31.6%)" LNKDGLWLEK root 4.2.1.2 (100%) fumarate hydratase (100%) "GO:0006099 (21.1%) GO:0006106 (0.2%)" "GO:0005829 (0.1%) GO:0016020 (0.1%)" "GO:0046872 (21.1%) GO:0051539 (21.1%) GO:0004333 (21%)" "tricarboxylic acid cycle (21.1%) fumarate metabolic process (0.2%)" "cytosol (0.1%) membrane (0.1%)" "metal ion binding (21.1%) 4 iron, 4 sulfur cluster binding (21.1%) fumarate hydratase activity (21%)" "IPR004647 (17.1%) IPR051208 (17.1%) IPR004646 (17%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (17.1%) Class-I Fumarase/Tartrate Dehydratase (17.1%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (17%)" SFPEYLGSAEYMTLYNEAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR012910 (34.4%) IPR023996 (31.3%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (31.3%) TonB-dependent receptor, plug domain superfamily (31.3%)" TLLGYGNHLLEPEVGFLASGLEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.4%) GO:0015941 (14.4%)" GO:0071513 (14%) "GO:0004632 (14.4%) GO:0004633 (14.4%) GO:0010181 (14.4%)" "coenzyme A biosynthetic process (14.4%) pantothenate catabolic process (14.4%)" phosphopantothenoylcysteine decarboxylase complex (14%) "phosphopantothenate--cysteine ligase activity (14.4%) phosphopantothenoylcysteine decarboxylase activity (14.4%) FMN binding (14.4%)" "IPR003382 (20.5%) IPR005252 (20.5%) IPR007085 (20.5%)" "Flavoprotein (20.5%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.5%) DNA/pantothenate metabolism flavoprotein, C-terminal (20.5%)" DNDLLVLECNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (13.4%) GO:0006526 (13%) GO:0006221 (12.7%)" GO:0005737 (13.4%) "GO:0004088 (13.4%) GO:0005524 (13.4%) GO:0046872 (13.4%)" "glutamine metabolic process (13.4%) L-arginine biosynthetic process (13%) pyrimidine nucleotide biosynthetic process (12.7%)" cytoplasm (13.4%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.4%) ATP binding (13.4%) metal ion binding (13.4%)" "IPR005479 (10.2%) IPR011761 (10.2%) IPR005480 (10%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.2%) ATP-grasp fold (10.2%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%)" DLNEGTLTEDEAQELLDHLVMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" RYDFLDK root "3.1.1.- (85.7%) 2.4.2.8 (4.8%) 1.16.3.1 (2.4%)" "Carboxylic ester hydrolases (85.7%) hypoxanthine phosphoribosyltransferase (4.8%) ferroxidase (2.4%)" "GO:0006508 (6.1%) GO:0046928 (2.8%) GO:0006166 (1.1%)" "GO:0016020 (3.3%) GO:0030672 (2.8%) GO:0005886 (2.2%)" "GO:0016787 (21%) GO:0008236 (3.9%) GO:0008239 (3.9%)" "proteolysis (6.1%) regulation of neurotransmitter secretion (2.8%) purine ribonucleoside salvage (1.1%)" "membrane (3.3%) synaptic vesicle membrane (2.8%) plasma membrane (2.2%)" "hydrolase activity (21%) serine-type peptidase activity (3.9%) dipeptidyl-peptidase activity (3.9%)" "IPR029058 (12.7%) IPR002018 (10.2%) IPR050309 (10.2%)" "Alpha/Beta hydrolase fold (12.7%) Carboxylesterase, type B (10.2%) Type-B Carboxylesterase/Lipase (10.2%)" DFTFNSGLNFSYQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TVLETVEALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025578 (50%) IPR025640 (50%)" "Protein of unknown function DUF4359 (50%) GYF domain 2 (50%)" TFSFVVNK Bacteria Bacteria GO:0009116 (7.1%) GO:0042601 (7.1%) "GO:0016788 (64.3%) GO:0003913 (7.1%) GO:0051539 (7.1%)" nucleoside metabolic process (7.1%) endospore-forming forespore (7.1%) "hydrolase activity, acting on ester bonds (64.3%) DNA photolyase activity (7.1%) 4 iron, 4 sulfur cluster binding (7.1%)" "IPR008979 (23.7%) IPR013830 (23.7%) IPR036514 (23.7%)" "Galactose-binding-like domain superfamily (23.7%) SGNH hydrolase-type esterase domain (23.7%) SGNH hydrolase superfamily (23.7%)" YGTFPSASLGWNLMNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LPELLGLDQDGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.24 (100%) thioredoxin-dependent peroxiredoxin (100%) "GO:0034599 (25%) GO:0045454 (25%)" GO:0005737 (25%) GO:0008379 (25%) "cellular response to oxidative stress (25%) cell redox homeostasis (25%)" cytoplasm (25%) thioredoxin peroxidase activity (25%) "IPR000866 (20.5%) IPR013766 (20.5%) IPR050924 (20.5%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.5%) Thioredoxin domain (20.5%) Thiol-specific peroxidase BCP/PrxQ (20.5%)" VDATTLDLTNSGESLFSSVLNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) GLSSLVVAEDNYGEGSSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.2%) GO:0005829 (20.2%) "GO:0003994 (20.2%) GO:0051539 (20.2%) GO:0046872 (19.3%)" tricarboxylic acid cycle (20.2%) cytosol (20.2%) "aconitate hydratase activity (20.2%) 4 iron, 4 sulfur cluster binding (20.2%) metal ion binding (19.3%)" "IPR000573 (11.5%) IPR050926 (11.5%) IPR001030 (11.2%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.5%) Aconitase/IPM Isomerase (11.5%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.2%)" SGEEYQQPEEAVDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003676 (100%) nucleic acid binding (100%) "IPR003509 (36.8%) IPR011335 (31.6%) IPR011856 (31.6%)" "UPF0102 protein YraN-like (36.8%) Restriction endonuclease type II-like (31.6%) tRNA endonuclease-like domain superfamily (31.6%)" LLDVLDNGTRLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" NFGDNLVEDQKLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.4%) GO:0022627 (20.4%) "GO:0003735 (20.4%) GO:0019843 (20.4%) GO:0003729 (18.5%)" translation (20.4%) cytosolic small ribosomal subunit (20.4%) "structural constituent of ribosome (20.4%) rRNA binding (20.4%) mRNA binding (18.5%)" "IPR001351 (11%) IPR004044 (11%) IPR004087 (11%)" "Small ribosomal subunit protein uS3, C-terminal (11%) K Homology domain, type 2 (11%) K Homology domain (11%)" QVLNLTNNK root 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0046373 (38.8%) GO:0007165 (4.7%) GO:0002224 (1.2%)" "GO:0005886 (5.9%) GO:0016020 (1.2%)" "GO:0046556 (40%) GO:0038023 (2.4%) GO:0004888 (1.2%)" "L-arabinose metabolic process (38.8%) signal transduction (4.7%) toll-like receptor signaling pathway (1.2%)" "plasma membrane (5.9%) membrane (1.2%)" "alpha-L-arabinofuranosidase activity (40%) signaling receptor activity (2.4%) transmembrane signaling receptor activity (1.2%)" "IPR003305 (14.5%) IPR051563 (14.5%) IPR010720 (14%)" "Carbohydrate-binding, CenC-like (14.5%) Glycosyl Hydrolase Family 51 (14.5%) Alpha-L-arabinofuranosidase, C-terminal (14%)" VNQELNKFEQENQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR007624 (11.5%) IPR007627 (11.5%) IPR007630 (11.5%)" "RNA polymerase sigma-70 region 3 (11.5%) RNA polymerase sigma-70 region 2 (11.5%) RNA polymerase sigma-70 region 4 (11.5%)" DLTFSVNFGTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" HLSFYNMLEK Pseudomonadati Bacteria Pseudomonadati IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) NYLLTSLSFAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" TGLQPDLTVLVVTLQALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) GO:0035999 (33.3%) "GO:0004329 (33.3%) GO:0005524 (33.3%)" tetrahydrofolate interconversion (33.3%) "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.1%) IPR020628 (34.1%) IPR027417 (31.9%)" "Formate-tetrahydrofolate ligase, FTHFS (34.1%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (34.1%) P-loop containing nucleoside triphosphate hydrolase (31.9%)" VKGPVHLNVPLSEPFYSFTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.9 (100%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (100%) GO:0009234 (20.4%) "GO:0030976 (21%) GO:0070204 (20.4%) GO:0000287 (19.2%)" menaquinone biosynthetic process (20.4%) "thiamine pyrophosphate binding (21%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (20.4%) magnesium ion binding (19.2%)" "IPR012001 (26.1%) IPR004433 (25.4%) IPR029061 (24.6%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (26.1%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (25.4%) Thiamin diphosphate-binding fold (24.6%)" LNCESTACENKDATPDYLYLGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (20%) GO:0019288 (20%)" "GO:0005506 (20%) GO:0046429 (20%) GO:0051539 (20%)" "terpenoid biosynthetic process (20%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (20%)" "iron ion binding (20%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR004588 (25%) IPR011005 (25%) IPR017178 (25%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (25%) Dihydropteroate synthase-like superfamily (25%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (25%)" KSEDVFNPFSLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.9%) IPR012547 (30.9%) IPR027417 (30.2%)" "AAA-ATPase-like domain (38.9%) PD-(D/E)XK nuclease superfamily 9 (30.9%) P-loop containing nucleoside triphosphate hydrolase (30.2%)" LQAALDDLNALLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LYTPACLLLWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR006598 (50%) IPR051091 (50%)" "Glycosyl transferase CAP10 domain (50%) Protein O-Glucosyltransferase/Glycosyltransferase 90 (50%)" TVVLPATEVVTTNEFFDYDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (15%) GO:0008360 (13.3%) GO:0009252 (13.3%)" GO:0005737 (13.3%) "GO:0005524 (15%) GO:0008716 (15%) GO:0046872 (15%)" "cell wall organization (15%) regulation of cell shape (13.3%) peptidoglycan biosynthetic process (13.3%)" cytoplasm (13.3%) "ATP binding (15%) D-alanine-D-alanine ligase activity (15%) metal ion binding (15%)" "IPR000291 (14.8%) IPR005905 (14.8%) IPR011095 (14.8%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.8%) D-alanine--D-alanine ligase (14.8%) D-alanine--D-alanine ligase, C-terminal (14.8%)" KYGDDMVDLVR root GO:0016020 (50%) GO:0016301 (50%) membrane (50%) kinase activity (50%) "IPR024299 (23.8%) IPR035376 (23.8%) IPR038143 (23.8%)" "NigD-like N-terminal OB domain (23.8%) NigD-like, C-terminal domain (23.8%) NigD-like, C-terminal domain superfamily (23.8%)" EHLALPNKEDVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.99.17 (100%) phosphomethylpyrimidine synthase (100%) "GO:0009228 (16.8%) GO:0009229 (16.1%)" GO:0005829 (16.8%) "GO:0051539 (16.8%) GO:0008270 (16.1%) GO:0016830 (8.7%)" "thiamine biosynthetic process (16.8%) thiamine diphosphate biosynthetic process (16.1%)" cytosol (16.8%) "4 iron, 4 sulfur cluster binding (16.8%) zinc ion binding (16.1%) carbon-carbon lyase activity (8.7%)" "IPR002817 (25%) IPR025747 (25%) IPR037509 (25%)" "Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B (25%) ThiC-associated domain (25%) Phosphomethylpyrimidine synthase (25%)" GVDPNGQLYALK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005146 (7.9%) IPR005147 (7.9%) IPR045060 (7.9%)" "B3/B4 tRNA-binding domain (7.9%) tRNA synthetase, B5-domain (7.9%) Phenylalanine-tRNA ligase, class IIc, beta subunit (7.9%)" LDLPAPTAEEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.3%) GO:0005829 (20.3%) "GO:0004832 (20.3%) GO:0005524 (20.3%) GO:0002161 (18.8%)" valyl-tRNA aminoacylation (20.3%) cytosol (20.3%) "valine-tRNA ligase activity (20.3%) ATP binding (20.3%) aminoacyl-tRNA deacylase activity (18.8%)" "IPR001412 (9.4%) IPR002300 (9.4%) IPR002303 (9.4%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.4%) Aminoacyl-tRNA synthetase, class Ia (9.4%) Valine-tRNA ligase (9.4%)" VGADLYSMSMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (13.2%) GO:0009279 (86.8%) iron ion transport (13.2%) cell outer membrane (86.8%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" AAPMTYDLQTWGWTTDAVAHPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (80%) GO:0015344 (20%) cell outer membrane (80%) siderophore uptake transmembrane transporter activity (20%) "IPR036942 (80%) IPR039426 (20%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (80%) TonB-dependent receptor-like (20%)" TNYEEPLPGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0042910 (50%) plasma membrane (50%) xenobiotic transmembrane transporter activity (50%) "IPR001036 (54.2%) IPR027463 (45.8%)" "Acriflavin resistance protein (54.2%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (45.8%)" RYPAFGNLVPR root "1.3.5.1 (96.6%) 1.3.5.4 (2.5%) 1.3.99.1 (0.9%)" "succinate dehydrogenase (96.6%) Transferred entry: 1.3.5.1 (2.5%) Deleted entry (0.9%)" GO:0009061 (19.5%) GO:0005886 (19.5%) "GO:0009055 (19.5%) GO:0050660 (19.5%) GO:0000104 (15.4%)" anaerobic respiration (19.5%) plasma membrane (19.5%) "electron transfer activity (19.5%) flavin adenine dinucleotide binding (19.5%) succinate dehydrogenase activity (15.4%)" "IPR003953 (14.3%) IPR030664 (14.3%) IPR027477 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily (14.3%)" TSSYNLGVNGGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" VVTGGGVYGTVKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015031 (50%) GO:0005886 (50%) protein transport (50%) plasma membrane (50%) IPR003849 (100%) Preprotein translocase YajC (100%) RLDLLNLR root "2.7.7.59 (22.2%) 3.1.4.- (22.2%) 2.1.1.228 (11.1%)" "[protein-PII] uridylyltransferase (22.2%) Phosphoric diester hydrolases (22.2%) tRNA (guanine(37)-N(1))-methyltransferase (11.1%)" "GO:0006623 (6.7%) GO:0045053 (6.7%) GO:0006869 (6.2%)" "GO:0009279 (14.9%) GO:0016020 (9.7%) GO:0005739 (6.2%)" "GO:0008083 (2.6%) GO:0005125 (2.1%) GO:0008081 (2.1%)" "protein targeting to vacuole (6.7%) protein retention in Golgi apparatus (6.7%) lipid transport (6.2%)" "cell outer membrane (14.9%) membrane (9.7%) mitochondrion (6.2%)" "growth factor activity (2.6%) cytokine activity (2.1%) phosphoric diester hydrolase activity (2.1%)" "IPR039426 (6.5%) IPR012910 (6.3%) IPR023997 (6.3%)" "TonB-dependent receptor-like (6.5%) TonB-dependent receptor, plug domain (6.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (6.3%)" TAEAMAALGR root GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VTAYEMTKPMSEDQEYYSNYDAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) DVAALYQSLLEHNVSLLAANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.1.1.3 (50.8%) 2.7.2.4 (49.2%)" "homoserine dehydrogenase (50.8%) aspartate kinase (49.2%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" VTLPVVGLSFDAAALYDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027385 (55.6%) IPR011250 (44.4%)" "Outer membrane protein, beta-barrel domain (55.6%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (44.4%)" QLLEHTPDLVLNVLDTSNLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25.2%) "GO:0005525 (25.2%) GO:0015093 (25.2%) GO:0046914 (24.5%)" plasma membrane (25.2%) "GTP binding (25.2%) ferrous iron transmembrane transporter activity (25.2%) transition metal ion binding (24.5%)" "IPR005225 (9.3%) IPR030389 (9.3%) IPR050860 (9.3%)" "Small GTP-binding domain (9.3%) FeoB-type guanine nucleotide-binding (G) domain (9.3%) Fe(2+) Transporter FeoB GTPase (9.3%)" RALLTLR root "2.7.2.1 (16.7%) 3.2.1.141 (7%) 2.7.13.3 (6%)" "acetate kinase (16.7%) 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (7%) histidine kinase (6%)" "GO:0006457 (1.8%) GO:0009408 (1.7%) GO:0007528 (1.7%)" "GO:0005737 (3.3%) GO:0005829 (3.3%) GO:0016020 (2.9%)" "GO:0005524 (4.9%) GO:0008270 (3.3%) GO:0003677 (2.1%)" "protein folding (1.8%) response to heat (1.7%) neuromuscular junction development (1.7%)" "cytoplasm (3.3%) cytosol (3.3%) membrane (2.9%)" "ATP binding (4.9%) zinc ion binding (3.3%) DNA binding (2.1%)" "IPR027417 (2.4%) IPR001623 (1.7%) IPR036869 (1.7%)" "P-loop containing nucleoside triphosphate hydrolase (2.4%) DnaJ domain (1.7%) Chaperone J-domain superfamily (1.7%)" EVLLDDLFKY Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLEPEYEGDFEDWDQMLDTNLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" HFLDAVSTQTVDLDFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50.4%) GO:0016887 (49.6%)" "ATP binding (50.4%) ATP hydrolysis activity (49.6%)" "IPR032781 (20.2%) IPR051309 (20.2%) IPR003439 (19.9%)" "ABC-transporter extension domain (20.2%) ABC transporter ABCF subfamily ATPase (20.2%) ABC transporter-like, ATP-binding domain (19.9%)" NNCYPLSVSSER Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.3%) IPR018223 (14.3%) IPR023434 (14.3%)" "Argininosuccinate synthase (14.3%) Argininosuccinate synthase, conserved site (14.3%) Argininosuccinate synthase, type 1 subfamily (14.3%)" NPNNFVALANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (42.3%) IPR011990 (38.5%) IPR050498 (19.2%)" "Tetratricopeptide repeat (42.3%) Tetratricopeptide-like helical domain superfamily (38.5%) Photosystem I assembly protein Ycf3 (19.2%)" VNLDNDGNLNLALENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (34.5%) IPR031107 (34.5%) IPR008978 (31%)" "Alpha crystallin/Hsp20 domain (34.5%) Small heat shock protein (34.5%) HSP20-like chaperone (31%)" QFTVGADVAYGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.1%) "GO:0004556 (32.4%) GO:0043169 (32.4%)" carbohydrate metabolic process (35.1%) "alpha-amylase activity (32.4%) cation binding (32.4%)" "IPR006047 (17.6%) IPR031965 (17.6%) IPR006046 (16.2%)" "Glycosyl hydrolase family 13, catalytic domain (17.6%) Starch-binding module 26 (17.6%) Alpha amylase (16.2%)" NFELSCFLYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" RNNDSDWLSNFFDDTLFNTEVMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (33.3%) IPR008978 (33.3%) IPR031107 (33.3%)" "Alpha crystallin/Hsp20 domain (33.3%) HSP20-like chaperone (33.3%) Small heat shock protein (33.3%)" FTLPLWNETPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) IPR003423 (100%) Outer membrane efflux protein (100%) ATAELESSENHDKLVLTELPYGVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.5%) IPR005743 (12.5%) IPR006691 (12.5%)" "DNA topoisomerase, type IIA, domain A (12.5%) DNA gyrase, subunit A (12.5%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.5%)" ALLLLGAR root "4.3.3.7 (52.3%) 2.7.13.3 (9.1%) 4.1.2.63 (6.1%)" "4-hydroxy-tetrahydrodipicolinate synthase (52.3%) histidine kinase (9.1%) 2-hydroxyacyl-CoA lyase (6.1%)" "GO:0097272 (4.7%) GO:0009089 (4.1%) GO:0019877 (4.1%)" "GO:0016020 (11.7%) GO:0005886 (7.7%) GO:0005829 (4.3%)" "GO:0008519 (4.8%) GO:0008840 (4.1%) GO:0005524 (2.8%)" "ammonium homeostasis (4.7%) lysine biosynthetic process via diaminopimelate (4.1%) diaminopimelate biosynthetic process (4.1%)" "membrane (11.7%) plasma membrane (7.7%) cytosol (4.3%)" "ammonium channel activity (4.8%) 4-hydroxy-tetrahydrodipicolinate synthase activity (4.1%) ATP binding (2.8%)" "IPR024041 (3.7%) IPR029020 (3.7%) IPR013785 (3.2%)" "Ammonium transporter AmtB-like domain (3.7%) Ammonium/urea transporter (3.7%) Aldolase-type TIM barrel (3.2%)" LELSYLGMNSQTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (21.4%) GO:0009279 (57.1%) GO:0015344 (21.4%) siderophore transmembrane transport (21.4%) cell outer membrane (57.1%) siderophore uptake transmembrane transporter activity (21.4%) "IPR012910 (13.8%) IPR023996 (13.8%) IPR023997 (13.8%)" "TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.8%)" TLQEFDLTAPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) YHAHDENNEANVGDTVMLMETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000266 (25%) IPR012340 (25%) IPR019979 (25%)" "Small ribosomal subunit protein uS17 (25%) Nucleic acid-binding, OB-fold (25%) Small ribosomal subunit protein uS17, conserved site (25%)" NGQLWVGSETGGVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (25%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR009057 (12.1%) IPR011110 (12.1%) IPR011123 (12.1%)" "Homedomain-like superfamily (12.1%) Two component regulator propeller (12.1%) Two component regulator three Y (12.1%)" GFGNTQLSATGNYNMHANADNTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TLPFGAVYDYFNLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.7%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.7%)" LLSYFVSK root "2.7.13.3 (60%) 2.4.1.227 (20%) 3.2.1.- (20%)" "histidine kinase (60%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (20%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (20%)" "GO:0005975 (1.6%) GO:0006013 (1.6%) GO:0006814 (1.6%)" "GO:0005737 (26.2%) GO:0016020 (14.8%) GO:0005886 (9.8%)" "GO:0000155 (6.6%) GO:0005524 (4.9%) GO:0015421 (3.3%)" "carbohydrate metabolic process (1.6%) mannose metabolic process (1.6%) sodium ion transport (1.6%)" "cytoplasm (26.2%) membrane (14.8%) plasma membrane (9.8%)" "phosphorelay sensor kinase activity (6.6%) ATP binding (4.9%) ABC-type oligopeptide transporter activity (3.3%)" "IPR002818 (11.3%) IPR006287 (11.3%) IPR029062 (11.3%)" "DJ-1/PfpI (11.3%) Protein/nucleic acid deglycase DJ-1 (11.3%) Class I glutamine amidotransferase-like (11.3%)" KLLHGDLDLTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (36.4%) IPR012944 (36.4%) IPR033985 (27.3%)" "Tetratricopeptide-like helical domain superfamily (36.4%) RagB/SusD domain (36.4%) SusD-like, N-terminal (27.3%)" NVQDELLR root "2.3.2.2 (50%) 3.4.13.19 (50%)" "gamma-glutamyltransferase (50%) membrane dipeptidase (50%)" "GO:0006508 (3.6%) GO:0032259 (3.6%)" "GO:0009279 (67.9%) GO:0005634 (3.6%) GO:0005694 (3.6%)" "GO:0008270 (3.6%) GO:0042054 (3.6%) GO:0046872 (3.6%)" "proteolysis (3.6%) methylation (3.6%)" "cell outer membrane (67.9%) nucleus (3.6%) chromosome (3.6%)" "zinc ion binding (3.6%) histone methyltransferase activity (3.6%) metal ion binding (3.6%)" "IPR012910 (14.4%) IPR023997 (14.4%) IPR039426 (14.4%)" "TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.4%) TonB-dependent receptor-like (14.4%)" YMTTSVAEMMVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.4%) IPR051802 (19.4%) IPR002890 (18.8%)" "Alpha-2-macroglobulin (19.4%) Alpha-2-macroglobulin-like (19.4%) Macroglobulin domain (18.8%)" LRPADVDVELYNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" WQQLFQFMVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) YTPQELSAMVLQK root "GO:0005737 (8.8%) GO:0070013 (0.1%)" "GO:0005524 (31.5%) GO:0140662 (31.5%) GO:0051082 (27.8%)" "cytoplasm (8.8%) intracellular organelle lumen (0.1%)" "ATP binding (31.5%) ATP-dependent protein folding chaperone (31.5%) unfolded protein binding (27.8%)" "IPR013126 (17.8%) IPR043129 (17.7%) IPR018181 (17.7%)" "Heat shock protein 70 family (17.8%) ATPase, nucleotide binding domain (17.7%) Heat shock protein 70, conserved site (17.7%)" GQTATFPLNQVLAGWTEGLQLMTEGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" TNVTLPEGMSVTFFGLAGGDAPTLNLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (33.3%) IPR012334 (33.3%) IPR033427 (33.3%)" "Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%) Domain of unknown function DUF5123 (33.3%)" TPLAQGLLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006354 (20.3%) GO:0032784 (20.3%)" "GO:0003677 (20.3%) GO:0070063 (20.3%) GO:0003746 (18.8%)" "DNA-templated transcription elongation (20.3%) regulation of DNA-templated transcription elongation (20.3%)" "DNA binding (20.3%) RNA polymerase binding (20.3%) translation elongation factor activity (18.8%)" "IPR001437 (14.3%) IPR006359 (14.3%) IPR022691 (14.3%)" "Transcription elongation factor, GreA/GreB, C-terminal (14.3%) Transcription elongation factor GreA (14.3%) Transcription elongation factor, GreA/GreB, N-terminal (14.3%)" GFDVTVFEALHELGGVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (49.3%) GO:0051536 (49.3%) GO:0004355 (1.4%)" "oxidoreductase activity (49.3%) iron-sulfur cluster binding (49.3%) glutamate synthase (NADPH) activity (1.4%)" "IPR023753 (11.3%) IPR028261 (11.3%) IPR036188 (11.3%)" "FAD/NAD(P)-binding domain (11.3%) Dihydroprymidine dehydrogenase domain II (11.3%) FAD/NAD(P)-binding domain superfamily (11.3%)" AHLLEGLLLACDNLDEVVHLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.5%) GO:0006261 (12.4%)" "GO:0005737 (12.5%) GO:0009330 (12.5%) GO:0005694 (12.4%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.4%)" "DNA topological change (12.5%) DNA-templated DNA replication (12.4%)" "cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%) chromosome (12.4%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.4%)" "IPR002205 (12.7%) IPR006691 (12.7%) IPR050220 (12.7%)" "DNA topoisomerase, type IIA, domain A (12.7%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.7%) Type II DNA Topoisomerases (12.7%)" NYQAVDLLNGLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR003961 (26.2%) IPR033803 (26.2%) IPR013783 (23.8%)" "Fibronectin type III (26.2%) Golvesin/Xly, CBD-like (26.2%) Immunoglobulin-like fold (23.8%)" YFLNGNTTETTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016829 (79.3%) GO:0004557 (20.7%)" "lyase activity (79.3%) alpha-galactosidase activity (20.7%)" "IPR052063 (35.9%) IPR012334 (32.8%) IPR011050 (31.3%)" "Polysaccharide Lyase 1 (35.9%) Pectin lyase fold (32.8%) Pectin lyase fold/virulence factor (31.3%)" YGNEAAEDTSLLYGGSCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.5%) GO:0006096 (12.5%) GO:0019563 (12.5%)" "GO:0005829 (12.5%) GO:0016020 (12.5%)" GO:0004807 (12.5%) "gluconeogenesis (12.5%) glycolytic process (12.5%) glycerol catabolic process (12.5%)" "cytosol (12.5%) membrane (12.5%)" triose-phosphate isomerase activity (12.5%) "IPR000652 (17%) IPR009908 (17%) IPR020861 (17%)" "Triosephosphate isomerase (17%) Methylamine utilisation protein, MauE (17%) Triosephosphate isomerase, active site (17%)" DKAQVGLELHSGK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.4%) IPR002942 (11.4%) IPR006145 (11.4%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.4%) RNA-binding S4 domain (11.4%) Pseudouridine synthase, RsuA/RluA-like (11.4%)" GLSAYVSGANLLTLSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR012910 (33.3%) IPR023996 (33.3%) IPR037066 (33.3%)" "TonB-dependent receptor, plug domain (33.3%) TonB-dependent outer membrane protein, SusC/RagA (33.3%) TonB-dependent receptor, plug domain superfamily (33.3%)" QTYEYVYGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VTSLASLTSPALDQPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri WGFFPSVAVGWR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006826 (4.2%) GO:0009279 (95.8%) iron ion transport (4.2%) cell outer membrane (95.8%) "IPR008969 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "Carboxypeptidase-like, regulatory domain superfamily (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" DVTSMTDETTGYLSEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" HVAVAGGVSANNGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (22.5%) GO:0006508 (4.5%)" GO:0005737 (22.5%) "GO:0005506 (22.5%) GO:0061711 (16.1%) GO:0016747 (6.4%)" "tRNA threonylcarbamoyladenosine modification (22.5%) proteolysis (4.5%)" cytoplasm (22.5%) "iron ion binding (22.5%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (16.1%) acyltransferase activity, transferring groups other than amino-acyl groups (6.4%)" "IPR000905 (20.2%) IPR017861 (20.2%) IPR022450 (20.2%)" "Gcp-like domain (20.2%) Kae1/TsaD family (20.2%) tRNA N6-adenosine threonylcarbamoyltransferase, TsaD (20.2%)" GESFEVLCETLKR Bacteria Bacteria IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) QFDNYTMAQDVYNVTADQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" WDVLVAGLK root "2.1.1.13 (98.9%) 2.5.1.15 (1.1%)" "methionine synthase (98.9%) dihydropteroate synthase (1.1%)" "GO:0032259 (14%) GO:0046653 (14%) GO:0050667 (14%)" "GO:0005829 (14%) GO:0005886 (0.2%) GO:0016459 (0.2%)" "GO:0008705 (14%) GO:0031419 (14%) GO:0008270 (13.5%)" "methylation (14%) tetrahydrofolate metabolic process (14%) homocysteine metabolic process (14%)" "cytosol (14%) plasma membrane (0.2%) myosin complex (0.2%)" "methionine synthase activity (14%) cobalamin binding (14%) zinc ion binding (13.5%)" "IPR000489 (9.2%) IPR050554 (9.2%) IPR003759 (8.9%)" "Pterin-binding domain (9.2%) Methionine Synthase/Corrinoid (9.2%) Cobalamin (vitamin B12)-binding module, cap domain (8.9%)" AAQSLAAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) GO:0022900 (25%) GO:0005886 (25%) "GO:0009055 (25%) GO:0010181 (25%)" electron transport chain (25%) plasma membrane (25%) "electron transfer activity (25%) FMN binding (25%)" "IPR007329 (50%) IPR010209 (50%)" "FMN-binding (50%) Ion-translocating oxidoreductase complex, subunit RnfG/RsxG (50%)" NHGHVLNLGSVAGDAAYAGGNVYCATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" AHPDVFNTLLQVLDDGR root "GO:0034605 (17.7%) GO:0042026 (11.1%) GO:0006508 (8%)" GO:0005737 (17.7%) "GO:0005524 (17.7%) GO:0016887 (17.7%) GO:0008233 (8%)" "cellular response to heat (17.7%) protein refolding (11.1%) proteolysis (8%)" cytoplasm (17.7%) "ATP binding (17.7%) ATP hydrolysis activity (17.7%) peptidase activity (8%)" "IPR003593 (8.4%) IPR003959 (8.4%) IPR050130 (8.4%)" "AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.4%)" KALTEAEGDFDK Bacteria Bacteria GO:0005737 (49.9%) GO:0003746 (50.1%) cytoplasm (49.9%) translation elongation factor activity (50.1%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" LDSLDTLHEAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0002949 (22.7%) GO:0005737 (22.7%) "GO:0005524 (22.7%) GO:0046872 (22.7%) GO:0016740 (6.8%)" tRNA threonylcarbamoyladenosine modification (22.7%) cytoplasm (22.7%) "ATP binding (22.7%) metal ion binding (22.7%) transferase activity (6.8%)" "IPR003442 (52.6%) IPR027417 (47.4%)" "tRNA threonylcarbamoyl adenosine modification protein TsaE (52.6%) P-loop containing nucleoside triphosphate hydrolase (47.4%)" ELEKDFDVTVLTQNVDNLHEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.3.1.286 (100%) protein acetyllysine N-acetyltransferase (100%) "GO:0017136 (50%) GO:0070403 (50%)" "histone deacetylase activity, NAD-dependent (50%) NAD+ binding (50%)" "IPR003000 (20.6%) IPR026590 (20.6%) IPR050134 (20.6%)" "Sirtuin family (20.6%) Sirtuin family, catalytic core domain (20.6%) NAD-dependent sirtuin protein deacylases (20.6%)" MGGLPVWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006654 (50%) GO:0003841 (50%) phosphatidic acid biosynthetic process (50%) 1-acylglycerol-3-phosphate O-acyltransferase activity (50%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) QGEKPLSLLEDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" VLDDSEYADGNHSLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.8 (100%) mannose-6-phosphate isomerase (100%) "GO:0005976 (25.4%) GO:0009298 (25.4%)" "GO:0004475 (25.4%) GO:0000166 (22.2%) GO:0004476 (1.6%)" "polysaccharide metabolic process (25.4%) GDP-mannose biosynthetic process (25.4%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (25.4%) nucleotide binding (22.2%) mannose-6-phosphate isomerase activity (1.6%)" "IPR001538 (18%) IPR051161 (18%) IPR005835 (16.9%)" "Mannose-6-phosphate isomerase, type II, C-terminal (18%) Mannose-6-phosphate isomerase type 2 (18%) Nucleotidyl transferase domain (16.9%)" NNFQEGDTYEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR022385 (17.6%) IPR050708 (17.6%) IPR006530 (15.7%)" "Rhs repeat-associated core (17.6%) Type VI secretion system VgrG/RHS (17.6%) YD repeat (15.7%)" VYLYPSHDLPSPLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.4 (100%) cellulase (100%) "GO:0045493 (25%) GO:0030245 (20.2%)" "GO:0004553 (25%) GO:0030246 (23.8%) GO:0016829 (6%)" "xylan catabolic process (25%) cellulose catabolic process (20.2%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (25%) carbohydrate binding (23.8%) lyase activity (6%)" "IPR006710 (14.3%) IPR052176 (14.3%) IPR005084 (13.6%)" "Glycoside hydrolase, family 43 (14.3%) Glycosyl Hydrolase Family 43 Enzymes (14.3%) Carbohydrate binding module family 6 (13.6%)" KLFFAGMNVVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (2.4%) "GO:0000287 (19.6%) GO:0004743 (19.6%) GO:0016301 (19.6%)" response to stress (2.4%) "magnesium ion binding (19.6%) pyruvate kinase activity (19.6%) kinase activity (19.6%)" "IPR001697 (11.3%) IPR015793 (11.3%) IPR015795 (11.3%)" "Pyruvate kinase (11.3%) Pyruvate kinase, barrel (11.3%) Pyruvate kinase, C-terminal (11.3%)" FLQSGLMK root "GO:0044341 (32.7%) GO:0006355 (0.9%)" GO:0005886 (32.7%) "GO:0005436 (32.7%) GO:0003677 (0.9%)" "sodium-dependent phosphate transport (32.7%) regulation of DNA-templated transcription (0.9%)" plasma membrane (32.7%) "sodium:phosphate symporter activity (32.7%) DNA binding (0.9%)" "IPR003841 (41.2%) IPR038078 (38.8%) IPR026022 (8.2%)" "Sodium-dependent phosphate transport protein (41.2%) PhoU-like domain superfamily (38.8%) PhoU domain (8.2%)" AQFTEVSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR001787 (33.3%) IPR028909 (33.3%) IPR036164 (33.3%)" "Large ribosomal subunit protein bL21 (33.3%) Large ribosomal subunit protein bL21-like (33.3%) Large ribosomal subunit protein bL21-like superfamily (33.3%)" SSYLDYSMSVLVAR Bacteria Bacteria 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.1%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.1%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (12.7%) IPR050220 (12.7%) IPR006691 (12.5%)" "DNA topoisomerase, type IIA, domain A (12.7%) Type II DNA Topoisomerases (12.7%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.5%)" DPLGVLPLYLGYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" DLADDYYDFDEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (25%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (25%)" "IPR001900 (12.5%) IPR003029 (12.5%) IPR004476 (12.5%)" "Ribonuclease II/R (12.5%) S1 domain (12.5%) Ribonuclease II/ribonuclease R (12.5%)" LLQEEELLK root "1.8.3.2 (50%) 3.1.21.3 (50%)" "thiol oxidase (50%) type I site-specific deoxyribonuclease (50%)" "GO:0006457 (15.4%) GO:0006672 (0.5%) GO:0009307 (0.5%)" "GO:0005829 (22%) GO:0016020 (1.6%) GO:0005737 (1.1%)" "GO:0051082 (15.9%) GO:0051087 (13.2%) GO:0003677 (9.9%)" "protein folding (15.4%) ceramide metabolic process (0.5%) DNA restriction-modification system (0.5%)" "cytosol (22%) membrane (1.6%) cytoplasm (1.1%)" "unfolded protein binding (15.9%) protein-folding chaperone binding (13.2%) DNA binding (9.9%)" "IPR002939 (11.1%) IPR008971 (10.3%) IPR051339 (10.3%)" "Chaperone DnaJ, C-terminal (11.1%) HSP40/DnaJ peptide-binding (10.3%) DnaJ homolog subfamily B (10.3%)" SQDQSRPVQYEQAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.7%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.7%)" "IPR006101 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Glycoside hydrolase, family 2 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" YLDEHDQQYDLLVLDPPAFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0032259 (22.2%) GO:0006364 (17.5%)" GO:0005737 (19%) "GO:0008168 (22.2%) GO:0003723 (19%)" "methylation (22.2%) rRNA processing (17.5%)" cytoplasm (19%) "methyltransferase activity (22.2%) RNA binding (19%)" "IPR019614 (19.2%) IPR029063 (17.8%) IPR002478 (16.4%)" "S-adenosylmethionine-dependent methyltransferase (19.2%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (17.8%) PUA domain (16.4%)" MKVTAPLLYSYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SSFTGSAGVVDADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" KAADEGNCVFVGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) LSLFELNSLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.11.6 (100%) exodeoxyribonuclease VII (100%) GO:0006308 (19.6%) "GO:0005737 (19.6%) GO:0009318 (19.6%)" "GO:0003676 (21.6%) GO:0008855 (19.6%)" DNA catabolic process (19.6%) "cytoplasm (19.6%) exodeoxyribonuclease VII complex (19.6%)" "nucleic acid binding (21.6%) exodeoxyribonuclease VII activity (19.6%)" "IPR025824 (35.5%) IPR003753 (32.3%) IPR020579 (32.3%)" "OB-fold nucleic acid binding domain (35.5%) Exonuclease VII, large subunit (32.3%) Exonuclease VII, large subunit, C-terminal (32.3%)" ATFGEENLEELFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20%) IPR019819 (20%) IPR019826 (20%)" "Carboxylesterase, type B (20%) Carboxylesterase type B, conserved site (20%) Carboxylesterase type B, active site (20%)" TQYEAGLNFHLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.6%) IPR023614 (48.4%)" "Phosphate-selective porin O/P (51.6%) Porin domain superfamily (48.4%)" QDSLCLCLHQLFPNLSESDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071555 (25.8%) GO:0005886 (25.8%) "GO:0008658 (25.8%) GO:0004180 (22.7%)" cell wall organization (25.8%) plasma membrane (25.8%) "penicillin binding (25.8%) carboxypeptidase activity (22.7%)" "IPR005311 (17.5%) IPR050515 (17.5%) IPR001460 (16.5%)" "Penicillin-binding protein, dimerisation domain (17.5%) Class D beta-lactamase/transpeptidase (17.5%) Penicillin-binding protein, transpeptidase (16.5%)" EDLLSLMVLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR006598 (50%) IPR051091 (50%)" "Glycosyl transferase CAP10 domain (50%) Protein O-Glucosyltransferase/Glycosyltransferase 90 (50%)" VLHLQDSSFLEEGKGYNEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0004601 (100%) peroxidase activity (100%) "IPR013766 (20.8%) IPR012336 (20.1%) IPR050553 (20.1%)" "Thioredoxin domain (20.8%) Thioredoxin-like fold (20.1%) Thioredoxin family ResA/DsbE subfamily (20.1%)" VLVLDLDPQCNLSSLFGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (33.3%) IPR027417 (33.3%) IPR050678 (33.3%)" "AAA domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) DNA Partitioning ATPase (33.3%)" GVFLSNQSVSDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (50%) IPR012640 (25%) IPR013783 (25%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%) Membrane lipoprotein, lipid attachment site (25%) Immunoglobulin-like fold (25%)" AWAAQTLER Bacteria Bacteria 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0005975 (32.1%) GO:0045493 (1.4%) GO:0046373 (0.7%)" "GO:0004553 (32.9%) GO:0030246 (32.1%) GO:0046556 (0.7%)" "carbohydrate metabolic process (32.1%) xylan catabolic process (1.4%) L-arabinose metabolic process (0.7%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (32.9%) carbohydrate binding (32.1%) alpha-L-arabinofuranosidase activity (0.7%)" "IPR006710 (12.9%) IPR023296 (12.4%) IPR005084 (12.1%)" "Glycoside hydrolase, family 43 (12.9%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (12.4%) Carbohydrate binding module family 6 (12.1%)" AEKNNVTLASAPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (20.7%) IPR051795 (20.7%) IPR006710 (20.1%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (20.7%) Glycosyl Hydrolase Family 43 (20.7%) Glycoside hydrolase, family 43 (20.1%)" GELSGNSLQVDATELEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" EDLCGCGNLLEQDNTPLADLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" RSVFLSPALSYSGWSNMGTHEVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" LEEALDWVSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.4%) IPR019998 (17.4%) IPR028053 (17.4%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.4%) Membrane insertase YidC (17.4%) Membrane insertase YidC, N-terminal (17.4%)" HRGPDWSGLYCGGSALLAHER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (24.9%) GO:0005829 (24.9%) "GO:0004066 (24.9%) GO:0005524 (24.9%) GO:0016874 (0.4%)" obsolete asparagine biosynthetic process (24.9%) cytosol (24.9%) "asparagine synthase (glutamine-hydrolyzing) activity (24.9%) ATP binding (24.9%) ligase activity (0.4%)" "IPR001962 (14.3%) IPR006426 (14.3%) IPR017932 (14.3%)" "Asparagine synthase (14.3%) Asparagine synthase, glutamine-hydrolyzing (14.3%) Glutamine amidotransferase type 2 domain (14.3%)" LTMLPMPEGVTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (10.9%) "GO:0000155 (30%) GO:0003700 (29.1%) GO:0043565 (29.1%)" membrane (10.9%) "phosphorelay sensor kinase activity (30%) DNA-binding transcription factor activity (29.1%) sequence-specific DNA binding (29.1%)" "IPR015943 (11.8%) IPR011110 (11.1%) IPR001789 (10.8%)" "WD40/YVTN repeat-like-containing domain superfamily (11.8%) Two component regulator propeller (11.1%) Signal transduction response regulator, receiver domain (10.8%)" DSLLAAPLLLDLTLLSDLAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (26.1%) GO:0008654 (26.1%)" GO:0016020 (21.7%) GO:0004512 (26.1%) "inositol biosynthetic process (26.1%) phospholipid biosynthetic process (26.1%)" membrane (21.7%) inositol-3-phosphate synthase activity (26.1%) "IPR002587 (33.7%) IPR013021 (33.7%) IPR036291 (32.6%)" "Myo-inositol-1-phosphate synthase (33.7%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.7%) NAD(P)-binding domain superfamily (32.6%)" GLVSADDYENALLTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (34%) IPR032317 (34%) IPR003423 (32%)" "RND efflux pump, membrane fusion protein (34%) Unknown (34%) Outer membrane efflux protein (32%)" KLAEDLNTNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (55.6%) IPR009057 (44.4%)" "AraC-like, DNA binding HTH domain (55.6%) Homedomain-like superfamily (44.4%)" LSLSAQNLFTLTGYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (15.4%) GO:0009279 (84.6%) iron ion transport (15.4%) cell outer membrane (84.6%) "IPR039426 (13.4%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like (13.4%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" TNEQTEQAVAAMYSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" ETETYLLSGSMLSTMDDNGQMGVAHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.5%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.5%) "IPR003284 (18.7%) IPR028994 (15.8%) IPR022045 (13.5%)" "Salmonella virulence plasmid 65kDa B protein (18.7%) Integrin alpha, N-terminal (15.8%) Insecticide toxin TcdB middle/N-terminal (13.5%)" LYGKDDDELYPNDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR012547 (41.7%) IPR018631 (41.7%) IPR027417 (16.7%)" "PD-(D/E)XK nuclease superfamily 9 (41.7%) AAA-ATPase-like domain (41.7%) P-loop containing nucleoside triphosphate hydrolase (16.7%)" SATEWAQYVEDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) VSAFNMSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025874 (89.7%) IPR011990 (10.3%)" "Double zinc ribbon (89.7%) Tetratricopeptide-like helical domain superfamily (10.3%)" NQADFALWK root 6.1.1.16 (100%) cysteine--tRNA ligase (100%) GO:0006423 (20.1%) "GO:0005829 (19.1%) GO:0005737 (1%)" "GO:0004817 (20.1%) GO:0005524 (20.1%) GO:0008270 (18.5%)" cysteinyl-tRNA aminoacylation (20.1%) "cytosol (19.1%) cytoplasm (1%)" "cysteine-tRNA ligase activity (20.1%) ATP binding (20.1%) zinc ion binding (18.5%)" "IPR014729 (14.8%) IPR024909 (14.8%) IPR032678 (14.8%)" "Rossmann-like alpha/beta/alpha sandwich fold (14.8%) Cysteinyl-tRNA synthetase/mycothiol ligase (14.8%) tRNA synthetases class I, catalytic domain (14.8%)" MSKYETEPGLVLCYGTMYGNTER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.6.3.- (100%) With oxygen as acceptor (100%) "GO:0010181 (25.7%) GO:0009055 (24.8%) GO:0016491 (24.8%)" "FMN binding (25.7%) electron transfer activity (24.8%) oxidoreductase activity (24.8%)" "IPR001279 (17%) IPR008254 (17%) IPR045761 (17%)" "Metallo-beta-lactamase (17%) Flavodoxin/nitric oxide synthase (17%) ODP domain (17%)" APEWNDALYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006537 (32.8%) "GO:0051536 (34.4%) GO:0016639 (32.8%)" glutamate biosynthetic process (32.8%) "iron-sulfur cluster binding (34.4%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (32.8%)" "IPR009051 (16.4%) IPR028261 (16.4%) IPR051394 (16.4%)" "Alpha-helical ferredoxin (16.4%) Dihydroprymidine dehydrogenase domain II (16.4%) Glutamate Synthase (16.4%)" QQQQLDFFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0003677 (100%) DNA binding (100%) IPR011204 (100%) Virulence protein RhuM-like (100%) LSKDDYLSLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" VDSLTGQAFLSLAQSVVTVVNRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016226 (16.7%) "GO:0005524 (16.7%) GO:0016887 (16.7%) GO:0046872 (16.7%)" iron-sulfur cluster assembly (16.7%) "ATP binding (16.7%) ATP hydrolysis activity (16.7%) metal ion binding (16.7%)" "IPR019591 (20%) IPR027417 (20%) IPR033756 (20%)" "Mrp/NBP35 ATP-binding protein (20%) P-loop containing nucleoside triphosphate hydrolase (20%) Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 (20%)" PGHLNPLYAQDNGVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.4.25 (50.2%) 4.1.99.12 (49.8%)" "GTP cyclohydrolase II (50.2%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (49.8%)" GO:0009231 (12.5%) GO:0005829 (12.5%) "GO:0003935 (12.5%) GO:0005525 (12.5%) GO:0008270 (12.5%)" riboflavin biosynthetic process (12.5%) cytosol (12.5%) "GTP cyclohydrolase II activity (12.5%) GTP binding (12.5%) zinc ion binding (12.5%)" "IPR000422 (16.8%) IPR000926 (16.8%) IPR032677 (16.8%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.8%) GTP cyclohydrolase II, RibA (16.8%) GTP cyclohydrolase II (16.8%)" LGYNLGGTAPLGMPATLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) CVGGLLFAR Pseudomonadati Bacteria Pseudomonadati GO:0005886 (53.3%) GO:0050660 (46.7%) plasma membrane (53.3%) flavin adenine dinucleotide binding (46.7%) "IPR002550 (13.3%) IPR000644 (12.8%) IPR005170 (12.8%)" "CNNM, transmembrane domain (13.3%) CBS domain (12.8%) Transporter-associated domain (12.8%)" MVCALNMFDETEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (25.1%) "GO:0005525 (25.1%) GO:0015093 (25.1%) GO:0046914 (24.6%)" plasma membrane (25.1%) "GTP binding (25.1%) ferrous iron transmembrane transporter activity (25.1%) transition metal ion binding (24.6%)" "IPR005225 (9.3%) IPR030389 (9.3%) IPR050860 (9.3%)" "Small GTP-binding domain (9.3%) FeoB-type guanine nucleotide-binding (G) domain (9.3%) Fe(2+) Transporter FeoB GTPase (9.3%)" QQNFETAYQELNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0030246 (51%) GO:0016798 (49%)" "carbohydrate binding (51%) hydrolase activity, acting on glycosyl bonds (49%)" "IPR013785 (12.9%) IPR014718 (12.9%) IPR019563 (12.9%)" "Aldolase-type TIM barrel (12.9%) Glycoside hydrolase-type carbohydrate-binding (12.9%) Glycosyl-hydrolase 97, catalytic domain (12.9%)" YLEVYNEAMAYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.-.- (75%) 2.4.1.246 (25%)" "Glycosyltransferases (75%) mannosylfructose-phosphate synthase (25%)" "GO:0016757 (96.8%) GO:0103011 (3.2%)" "glycosyltransferase activity (96.8%) mannosylfructose-phosphate synthase activity (3.2%)" IPR028098 (100%) Glycosyltransferase subfamily 4-like, N-terminal domain (100%) YTTNLMNNLEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.7%) IPR012910 (13.7%) IPR037066 (13.7%)" "Carboxypeptidase-like, regulatory domain superfamily (13.7%) TonB-dependent receptor, plug domain (13.7%) TonB-dependent receptor, plug domain superfamily (13.7%)" RALLDYLYDR root GO:0006412 (25.2%) "GO:0022627 (24.4%) GO:0005840 (0.8%) GO:1990904 (0.8%)" "GO:0003735 (25.2%) GO:0019843 (23.6%)" translation (25.2%) "cytosolic small ribosomal subunit (24.4%) ribosome (0.8%) ribonucleoprotein complex (0.8%)" "structural constituent of ribosome (25.2%) rRNA binding (23.6%)" "IPR000589 (33.7%) IPR009068 (33.7%) IPR005290 (32.6%)" "Small ribosomal subunit protein uS15 (33.7%) uS15/NS1, RNA-binding domain superfamily (33.7%) Small ribosomal subunit protein uS15, bacteria (32.6%)" TNANLFLTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000723 (25%) GO:0006281 (25%)" GO:0016020 (25%) GO:0003678 (25%) "telomere maintenance (25%) DNA repair (25%)" membrane (25%) DNA helicase activity (25%) "IPR010285 (20.7%) IPR003593 (20%) IPR027417 (20%)" "DNA helicase Pif1-like, DEAD-box helicase domain (20.7%) AAA+ ATPase domain (20%) P-loop containing nucleoside triphosphate hydrolase (20%)" SLMDGTVFR Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.2%) GO:0006102 (20.2%)" "GO:0004450 (20.2%) GO:0000287 (19.3%) GO:0051287 (19.3%)" "tricarboxylic acid cycle (20.2%) isocitrate metabolic process (20.2%)" "isocitrate dehydrogenase (NADP+) activity (20.2%) magnesium ion binding (19.3%) NAD binding (19.3%)" "IPR004790 (33.8%) IPR024084 (33.8%) IPR019818 (32.4%)" "Isocitrate dehydrogenase NADP-dependent (33.8%) Isopropylmalate dehydrogenase-like domain (33.8%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.4%)" SVNFDPLEK Pseudomonadati Bacteria Pseudomonadati "3.4.13.21 (50%) 3.4.21.- (50%)" "dipeptidase E (50%) Serine endopeptidases (50%)" GO:0006508 (47.4%) "GO:0008236 (47.4%) GO:0016805 (2.6%) GO:0016740 (1.3%)" proteolysis (47.4%) "serine-type peptidase activity (47.4%) dipeptidase activity (2.6%) transferase activity (1.3%)" "IPR005320 (48.6%) IPR029062 (48.6%) IPR004380 (1.4%)" "Peptidase S51 (48.6%) Class I glutamine amidotransferase-like (48.6%) Aspartate racemase (1.4%)" ERAYGDAEHNVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LFDWYQESLKD Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.271 (100%) GDP-L-fucose synthase (100%) GO:0042351 (24.2%) "GO:0050577 (27.3%) GO:0016853 (24.2%) GO:0070401 (24.2%)" 'de novo' GDP-L-fucose biosynthetic process (24.2%) "GDP-L-fucose synthase activity (27.3%) isomerase activity (24.2%) NADP+ binding (24.2%)" "IPR036291 (36%) IPR001509 (32%) IPR028614 (32%)" "NAD(P)-binding domain superfamily (36%) NAD-dependent epimerase/dehydratase (32%) GDP-L-fucose synthase/GDP-L-colitose synthase (32%)" NQLASSHHTLSGLLYDAVEDQLYTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016301 (96.8%) GO:0047590 (3.2%)" "kinase activity (96.8%) 5-dehydro-2-deoxygluconokinase activity (3.2%)" "IPR011611 (34.4%) IPR052700 (34.4%) IPR029056 (31.1%)" "Carbohydrate kinase PfkB (34.4%) Carbohydrate kinase PfkB-like (34.4%) Ribokinase-like (31.1%)" LAFGTGNHETTR Bacteria Bacteria 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (25.6%) "GO:0005840 (25%) GO:0005737 (23.9%)" "GO:0008276 (20.6%) GO:0016279 (5%)" methylation (25.6%) "ribosome (25%) cytoplasm (23.9%)" "protein methyltransferase activity (20.6%) protein-lysine N-methyltransferase activity (5%)" "IPR050078 (34.3%) IPR004498 (33.6%) IPR029063 (32.1%)" "Ribosomal protein L11 methyltransferase PrmA (34.3%) Ribosomal protein L11 methyltransferase (33.6%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (32.1%)" GNLNYFTLKEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.9%) IPR029483 (14.9%) IPR029486 (14.9%)" "Glycosyl-hydrolase 97, catalytic domain (14.9%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.9%) Glycosyl-hydrolase 97, N-terminal domain (14.9%)" ATGTLLESSLDKGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (25.1%) "GO:0003743 (25.1%) GO:0005525 (25.1%) GO:0003924 (24.7%)" cytoplasm (25.1%) "translation initiation factor activity (25.1%) GTP binding (25.1%) GTPase activity (24.7%)" "IPR015760 (8.9%) IPR023115 (8.9%) IPR044145 (8.9%)" "Translation initiation factor IF- 2 (8.9%) Translation initiation factor IF- 2, domain 3 (8.9%) Translation initiation factor IF-2, domain II (8.9%)" TLFEVLQFMSDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR000523 (13.5%) IPR004482 (13.5%) IPR045006 (13.5%)" "Magnesium chelatase ChlI-like, catalytic domain (13.5%) Mg chelatase-related protein (13.5%) Magnesium-chelatase subunit ChlI-like (13.5%)" YDVTFATAK Bacteria Bacteria "GO:0005576 (50%) GO:0016020 (50%)" "extracellular region (50%) membrane (50%)" "IPR013783 (33.3%) IPR019931 (33.3%) IPR032179 (33.3%)" "Immunoglobulin-like fold (33.3%) LPXTG cell wall anchor domain (33.3%) Pesticidal crystal protein Cry22Aa, Ig-like domain (33.3%)" SLTDQGLSAQLLLPEACQWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" ADGFYPGELMQYLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.6.4.13 (95.8%) 3.6.4.- (4.2%)" "RNA helicase (95.8%) Acting on ATP; involved in cellular and subcellular movement (4.2%)" GO:0005829 (9.9%) "GO:0003724 (22.5%) GO:0005524 (22.5%) GO:0016787 (22.5%)" cytosol (9.9%) "RNA helicase activity (22.5%) ATP binding (22.5%) hydrolase activity (22.5%)" "IPR000629 (10.1%) IPR001650 (10.1%) IPR005580 (10.1%)" "ATP-dependent RNA helicase DEAD-box, conserved site (10.1%) Helicase, C-terminal domain-like (10.1%) DEAD box helicase DbpA/CsdA, RNA-binding domain (10.1%)" EELFNMMHR root "IPR002912 (26.4%) IPR022986 (24.5%) IPR045865 (24.5%)" "ACT domain (26.4%) Uncharacterised protein family UPF0237, ACT-type (24.5%) ACT-like domain (24.5%)" GVNPDEVVAVGAALQGALLNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (33.6%) GO:0140662 (33.6%) GO:0051082 (32.8%)" "ATP binding (33.6%) ATP-dependent protein folding chaperone (33.6%) unfolded protein binding (32.8%)" "IPR013126 (16.9%) IPR018181 (16.7%) IPR029047 (16.7%)" "Heat shock protein 70 family (16.9%) Heat shock protein 70, conserved site (16.7%) Heat shock protein 70kD, peptide-binding domain superfamily (16.7%)" TYDTTQSLASVQEELVTQLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0043165 (50%) GO:0019867 (50%) Gram-negative-bacterium-type cell outer membrane assembly (50%) outer membrane (50%) IPR007485 (100%) LPS-assembly lipoprotein LptE (100%) CTFDNGLGSFEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (88%) IPR011250 (12%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (88%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (12%)" LGQLYACAGANRVPVEQLNAGDLGCTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" GGVSNGSGLESYYDLYPLPGNETK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" SLFFLGQVQGAEPLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (20.5%) IPR002469 (20.5%) IPR011659 (20.5%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (20.5%) Dipeptidylpeptidase IV, N-terminal domain (20.5%) WD40-like beta-propeller (20.5%)" TMTFTSWLTPDAQGMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.7%) IPR029483 (14.7%) IPR029486 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%)" AGLKLDWNLNEFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (17.1%) IPR057601 (17.1%) IPR008969 (16.4%)" "TonB-dependent receptor-like (17.1%) TonB-dependent transporter Oar-like, beta-barrel domain (17.1%) Carboxypeptidase-like, regulatory domain superfamily (16.4%)" YLHDVYELAECPFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.8.3.- (100%) CoA-transferases (100%) GO:0006083 (33.3%) "GO:0003986 (33.3%) GO:0008775 (33.3%)" acetate metabolic process (33.3%) "acetyl-CoA hydrolase activity (33.3%) acetate CoA-transferase activity (33.3%)" "IPR003702 (20.3%) IPR026888 (20.3%) IPR046433 (20.3%)" "Acetyl-CoA hydrolase/transferase, N-terminal (20.3%) Acetyl-CoA hydrolase/transferase, C-terminal domain (20.3%) Acetyl-CoA hydrolase/transferase (20.3%)" HNNWSLATDTGLLLHGPGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.8%) GO:0004356 (51.2%) glutamine biosynthetic process (48.8%) glutamine synthetase activity (51.2%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" YLTNGTYLSLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.8.1 (100%) short-chain acyl-CoA dehydrogenase (100%) "GO:0050660 (49.4%) GO:0016627 (48.2%) GO:0003995 (2.4%)" "flavin adenine dinucleotide binding (49.4%) oxidoreductase activity, acting on the CH-CH group of donors (48.2%) acyl-CoA dehydrogenase activity (2.4%)" "IPR009075 (10.2%) IPR020964 (10.2%) IPR052166 (10.2%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10.2%) Acyl-CoA dehydrogenase, C-terminal (10.2%) Diverse substrate specificity acyl-CoA dehydrogenase (10.2%)" NSEEECFAQLLSDFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TPANVLEGLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0052689 (50%) cell outer membrane (50%) carboxylic ester hydrolase activity (50%) "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" WAMNVVPAVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004674 (100%) protein serine/threonine kinase activity (100%) "IPR024361 (22.2%) IPR013783 (20.7%) IPR052595 (20.7%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (22.2%) Immunoglobulin-like fold (20.7%) Leucine-rich repeat-containing protein 69/Receptor-like (20.7%)" VLGLGETVLDLLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.1.- (50%) 2.7.1.4 (50%)" "Phosphotransferases with an alcohol group as acceptor (50%) fructokinase (50%)" "GO:0016301 (93%) GO:0008865 (7%)" "kinase activity (93%) fructokinase activity (7%)" "IPR011611 (25.4%) IPR002173 (25%) IPR050306 (25%)" "Carbohydrate kinase PfkB (25.4%) Carbohydrate/purine kinase, PfkB, conserved site (25%) PfkB Carbohydrate Kinase (25%)" GTDLDLVK root "1.8.1.4 (40%) 1.14.11.- (20%) 2.7.1.15 (20%)" "dihydrolipoyl dehydrogenase (40%) With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (20%) ribokinase (20%)" "GO:0005975 (6.8%) GO:0006103 (4.5%) GO:0015833 (4.5%)" "GO:0005886 (11.4%) GO:0042597 (4.5%) GO:0043190 (4.5%)" "GO:0008381 (9.1%) GO:0004148 (4.5%) GO:0016832 (4.5%)" "carbohydrate metabolic process (6.8%) 2-oxoglutarate metabolic process (4.5%) peptide transport (4.5%)" "plasma membrane (11.4%) periplasmic space (4.5%) ATP-binding cassette (ABC) transporter complex (4.5%)" "mechanosensitive monoatomic ion channel activity (9.1%) dihydrolipoyl dehydrogenase (NADH) activity (4.5%) aldehyde-lyase activity (4.5%)" "IPR013783 (17.2%) IPR014756 (16.1%) IPR002909 (15%)" "Immunoglobulin-like fold (17.2%) Immunoglobulin E-set (16.1%) IPT domain (15%)" FLNYLLVPLYTAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005886 (98.6%) GO:0016020 (1.4%)" "plasma membrane (98.6%) membrane (1.4%)" "IPR050833 (57.6%) IPR002797 (42.4%)" "Polysaccharide Biosynthesis and Transport (57.6%) Polysaccharide biosynthesis protein (42.4%)" LPVFVPEGSLLPVGPEMEWSDQKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" ALWNLNK root "3.1.1.4 (57.1%) 1.-.-.- (14.3%) 2.7.7.- (14.3%)" "phospholipase A2 (57.1%) Oxidoreductases (14.3%) Nucleotidyltransferases (14.3%)" "GO:0006364 (4%) GO:0044718 (3.4%) GO:0006644 (2.8%)" "GO:0009279 (16.4%) GO:0016020 (9%) GO:0032040 (5.1%)" "GO:0015344 (3.4%) GO:0004623 (2.8%) GO:0005509 (2.8%)" "rRNA processing (4%) siderophore transmembrane transport (3.4%) phospholipid metabolic process (2.8%)" "cell outer membrane (16.4%) membrane (9%) small-subunit processome (5.1%)" "siderophore uptake transmembrane transporter activity (3.4%) phospholipase A2 activity (2.8%) calcium ion binding (2.8%)" "IPR012910 (7.1%) IPR039426 (7.1%) IPR023996 (6.8%)" "TonB-dependent receptor, plug domain (7.1%) TonB-dependent receptor-like (7.1%) TonB-dependent outer membrane protein, SusC/RagA (6.8%)" MSGTVGVER root GO:0006412 (33.3%) "GO:0022625 (33.3%) GO:1990904 (0.1%)" GO:0003735 (33.4%) translation (33.3%) "cytosolic large ribosomal subunit (33.3%) ribonucleoprotein complex (0.1%)" structural constituent of ribosome (33.4%) "IPR001857 (29.1%) IPR008991 (29.1%) IPR038657 (29.1%)" "Large ribosomal subunit protein bL19 (29.1%) Translation protein SH3-like domain superfamily (29.1%) Large ribosomal subunit protein bL19 superfamily (29.1%)" GKQEGLVEGMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) YSGLTQEQLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) LDPVFSAK root 3.5.99.7 (100%) 1-aminocyclopropane-1-carboxylate deaminase (100%) "GO:0006826 (3%) GO:0022027 (3%) GO:0032880 (3%)" "GO:0005886 (24.2%) GO:0009279 (12.1%) GO:0005737 (3%)" "GO:0005283 (24.2%) GO:0005524 (6.1%) GO:0016887 (6.1%)" "iron ion transport (3%) interkinetic nuclear migration (3%) regulation of protein localization (3%)" "plasma membrane (24.2%) cell outer membrane (12.1%) cytoplasm (3%)" "amino acid:sodium symporter activity (24.2%) ATP binding (6.1%) ATP hydrolysis activity (6.1%)" "IPR001463 (14.3%) IPR008969 (7.1%) IPR012910 (7.1%)" "Sodium:alanine symporter (14.3%) Carboxypeptidase-like, regulatory domain superfamily (7.1%) TonB-dependent receptor, plug domain (7.1%)" LVPEGLAGR root 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006183 (19.5%) GO:0006177 (19.3%) GO:0006508 (0.7%)" "GO:0016020 (0.1%) GO:0035657 (0.1%)" "GO:0003938 (19.5%) GO:0046872 (19.3%) GO:0000166 (19.1%)" "GTP biosynthetic process (19.5%) GMP biosynthetic process (19.3%) proteolysis (0.7%)" "membrane (0.1%) eRF1 methyltransferase complex (0.1%)" "IMP dehydrogenase activity (19.5%) metal ion binding (19.3%) nucleotide binding (19.1%)" "IPR001093 (16.1%) IPR005990 (16.1%) IPR000644 (16%)" "IMP dehydrogenase/GMP reductase (16.1%) Inosine-5'-monophosphate dehydrogenase (16.1%) CBS domain (16%)" SLLPSSYSVVFDTPQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QDVCPCGCTSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.1.66 (100%) XTP/dITP diphosphatase (100%) "GO:0009117 (12.1%) GO:0009146 (11.6%) GO:0009143 (1%)" GO:0005829 (12.6%) "GO:0000166 (11.6%) GO:0017111 (11.6%) GO:0035870 (11.6%)" "nucleotide metabolic process (12.1%) purine nucleoside triphosphate catabolic process (11.6%) nucleoside triphosphate catabolic process (1%)" cytosol (12.6%) "nucleotide binding (11.6%) ribonucleoside triphosphate phosphatase activity (11.6%) dITP diphosphatase activity (11.6%)" "IPR002637 (35.1%) IPR020922 (32.4%) IPR029001 (32.4%)" "RdgB/HAM1 (35.1%) dITP/XTP pyrophosphatase (32.4%) Inosine triphosphate pyrophosphatase-like (32.4%)" QPYDYMGLNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR033985 (36.4%) IPR011990 (27.3%)" "RagB/SusD domain (36.4%) SusD-like, N-terminal (36.4%) Tetratricopeptide-like helical domain superfamily (27.3%)" RAHFYSNLNYYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" DKLYDLTQGTPGSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.7%) IPR050220 (20.7%) IPR013757 (19.5%)" "DNA topoisomerase, type IIA, domain A (20.7%) Type II DNA Topoisomerases (20.7%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.5%)" HPVLETQLPLGER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006298 (16.8%) GO:0005829 (16.8%) "GO:0005524 (16.8%) GO:0030983 (16.8%) GO:0140664 (16.8%)" mismatch repair (16.8%) cytosol (16.8%) "ATP binding (16.8%) mismatched DNA binding (16.8%) ATP-dependent DNA damage sensor activity (16.8%)" "IPR000432 (8.7%) IPR045076 (8.7%) IPR005748 (8.4%)" "DNA mismatch repair protein MutS, C-terminal (8.7%) DNA mismatch repair MutS (8.7%) DNA mismatch repair protein MutS (8.4%)" ELSNVLALPQPLEEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (25.9%) IPR053227 (25.9%) IPR027417 (24.1%)" "NadR/Ttd14, AAA domain (25.9%) TRPL channel trafficking regulator (25.9%) P-loop containing nucleoside triphosphate hydrolase (24.1%)" ADTELPAYNVTLDYMSGGLDMAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" GTYYELLGTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) LNDANAENDRLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (3.4%) GO:0016020 (93.1%) GO:0008233 (3.4%) proteolysis (3.4%) membrane (93.1%) peptidase activity (3.4%) "IPR006665 (27.6%) IPR050330 (27.6%) IPR036737 (25.5%)" "OmpA-like domain (27.6%) Bacterial Outer Membrane Structural/Functional (27.6%) OmpA-like domain superfamily (25.5%)" NDKDVSLTNLDLHGYASPDGPYDNNVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" LQEEGYDTVDANTHLGFKPDER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.5.4.25 (51.7%) 4.1.99.12 (48.3%)" "GTP cyclohydrolase II (51.7%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (48.3%)" GO:0009231 (12.7%) GO:0005829 (12.7%) "GO:0003935 (12.7%) GO:0005525 (12.7%) GO:0008686 (12.7%)" riboflavin biosynthetic process (12.7%) cytosol (12.7%) "GTP cyclohydrolase II activity (12.7%) GTP binding (12.7%) 3,4-dihydroxy-2-butanone-4-phosphate synthase activity (12.7%)" "IPR000422 (16.9%) IPR000926 (16.9%) IPR017945 (16.9%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.9%) GTP cyclohydrolase II, RibA (16.9%) DHBP synthase RibB-like alpha/beta domain superfamily (16.9%)" EKLDLPAPTAEEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.3%) GO:0005829 (20.3%) "GO:0004832 (20.3%) GO:0005524 (20.3%) GO:0002161 (18.8%)" valyl-tRNA aminoacylation (20.3%) cytosol (20.3%) "valine-tRNA ligase activity (20.3%) ATP binding (20.3%) aminoacyl-tRNA deacylase activity (18.8%)" "IPR001412 (9.4%) IPR002300 (9.4%) IPR002303 (9.4%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.4%) Aminoacyl-tRNA synthetase, class Ia (9.4%) Valine-tRNA ligase (9.4%)" AFEALLAR root "2.1.1.297 (45.6%) 2.7.1.56 (4.4%) 1.-.-.- (2.9%)" "peptide chain release factor N(5)-glutamine methyltransferase (45.6%) 1-phosphofructokinase (4.4%) Oxidoreductases (2.9%)" "GO:0032259 (4.7%) GO:0016052 (2.6%) GO:0044281 (2.6%)" "GO:0005829 (5.3%) GO:0016020 (4.4%) GO:0005737 (4%)" "GO:0005524 (5.8%) GO:0003676 (4%) GO:0008662 (2.6%)" "methylation (4.7%) carbohydrate catabolic process (2.6%) small molecule metabolic process (2.6%)" "cytosol (5.3%) membrane (4.4%) cytoplasm (4%)" "ATP binding (5.8%) nucleic acid binding (4%) 1-phosphofructokinase activity (2.6%)" "IPR029063 (2.6%) IPR051454 (2.6%) IPR020988 (2.5%)" "S-adenosyl-L-methionine-dependent methyltransferase superfamily (2.6%) RNA and ubiquinone modification enzymes (2.6%) Peptidase U32, collagenase (2.5%)" NATLFVNGGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) TVSEAMGLR root "1.6.5.9 (96.8%) 1.6.5.- (3.2%)" "NADH:ubiquinone reductase (non-electrogenic) (96.8%) With a quinone or similar compound as acceptor (3.2%)" "GO:0003954 (96.7%) GO:0050136 (3.3%)" "NADH dehydrogenase activity (96.7%) NADH dehydrogenase (quinone) (non-electrogenic) activity (3.3%)" "IPR023753 (25.1%) IPR045024 (25.1%) IPR054585 (24.7%)" "FAD/NAD(P)-binding domain (25.1%) Alternative NADH dehydrogenase (25.1%) External alternative NADH-ubiquinone oxidoreductase-like, C-terminal domain (24.7%)" LGTCGGLQLNCPAGTFVASQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.8%) IPR035994 (47.2%)" "Nucleoside phosphorylase domain (52.8%) Nucleoside phosphorylase superfamily (47.2%)" VDDVLSNPTQEEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" KNANNSNFEYVVAGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NYPYHFNLALSYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.8%) "GO:0016853 (33.8%) GO:0030246 (32.4%)" carbohydrate metabolic process (33.8%) "isomerase activity (33.8%) carbohydrate binding (32.4%)" "IPR008183 (25.6%) IPR037481 (25.6%) IPR011013 (24.4%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (25.6%) Protein LacX (25.6%) Galactose mutarotase-like domain superfamily (24.4%)" WVEYMTSDGDTPMAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (26.8%) IPR013780 (25.4%) IPR017853 (25.4%)" "Alpha-L-arabinofuranosidase, C-terminal (26.8%) Glycosyl hydrolase, all-beta (25.4%) Glycoside hydrolase superfamily (25.4%)" GGALVAWHPGVPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) LPLKELASYSLSLSSLTGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25.2%) "GO:0003746 (25.2%) GO:0005525 (25.2%) GO:0003924 (24.3%)" ribosome disassembly (25.2%) "translation elongation factor activity (25.2%) GTP binding (25.2%) GTPase activity (24.3%)" "IPR000640 (8%) IPR005517 (8%) IPR035649 (8%)" "Elongation factor EFG, domain V-like (8%) Translation elongation factor EFG/EF2, domain IV (8%) EFG, domain V (8%)" VSESGLSNPQTVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.48 (100%) indole-3-glycerol-phosphate synthase (100%) GO:0000162 (32.8%) "GO:0004425 (32.8%) GO:0004640 (32.8%) GO:0016757 (1.6%)" L-tryptophan biosynthetic process (32.8%) "indole-3-glycerol-phosphate synthase activity (32.8%) phosphoribosylanthranilate isomerase activity (32.8%) glycosyltransferase activity (1.6%)" "IPR013798 (21.1%) IPR045186 (21.1%) IPR001468 (20%)" "Indole-3-glycerol phosphate synthase domain (21.1%) Indole-3-glycerol phosphate synthase (21.1%) Indole-3-glycerol phosphate synthase, conserved site (20%)" YVVENSWTADNPSQSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" LHYLYQEGR Pseudomonadati Bacteria Pseudomonadati 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0044550 (20.1%) GO:0006633 (19.8%)" "GO:0005737 (19.5%) GO:0016020 (0.8%)" "GO:0004315 (19.8%) GO:0033818 (19.5%) GO:0005509 (0.3%)" "secondary metabolite biosynthetic process (20.1%) fatty acid biosynthetic process (19.8%)" "cytoplasm (19.5%) membrane (0.8%)" "3-oxoacyl-[acyl-carrier-protein] synthase activity (19.8%) beta-ketoacyl-acyl-carrier-protein synthase III activity (19.5%) calcium ion binding (0.3%)" "IPR013747 (23.6%) IPR016039 (23.6%) IPR013751 (23.3%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (23.6%) Thiolase-like (23.6%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (23.3%)" WETQEQTNLGLDLGLFNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GLMANVTPDQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (27.8%) IPR050280 (25.9%) IPR046357 (24.1%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (27.8%) Outer Membrane Protein Chaperone SurA (25.9%) Peptidyl-prolyl cis-trans isomerase domain superfamily (24.1%)" LGEFYLNYAEAAFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (36.8%) IPR012944 (36.8%) IPR033985 (26.3%)" "Tetratricopeptide-like helical domain superfamily (36.8%) RagB/SusD domain (36.8%) SusD-like, N-terminal (26.3%)" STCDYLATSTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0030246 (51.1%) GO:0016798 (48.9%)" "carbohydrate binding (51.1%) hydrolase activity, acting on glycosyl bonds (48.9%)" "IPR013785 (12.9%) IPR014718 (12.9%) IPR019563 (12.9%)" "Aldolase-type TIM barrel (12.9%) Glycoside hydrolase-type carbohydrate-binding (12.9%) Glycosyl-hydrolase 97, catalytic domain (12.9%)" TGQHVPQNYGEFCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.5 (100%) rhamnulokinase (100%) "GO:0006071 (20%) GO:0019301 (20%)" GO:0005829 (20%) "GO:0004370 (20%) GO:0008993 (20%)" "glycerol metabolic process (20%) rhamnose catabolic process (20%)" cytosol (20%) "glycerol kinase activity (20%) rhamnulokinase activity (20%)" "IPR013449 (21.2%) IPR018484 (21.2%) IPR018485 (21.2%)" "Rhamnulokinase (21.2%) Carbohydrate kinase FGGY, N-terminal (21.2%) Carbohydrate kinase FGGY, C-terminal (21.2%)" VLDLVQGNGFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" NQDFAPNYEGDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "Carboxypeptidase-like, regulatory domain superfamily (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" QELHSGDQVELLTQSNQKPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (43.1%) GO:0005886 (43.1%) GO:0016787 (13.7%) guanosine tetraphosphate metabolic process (43.1%) plasma membrane (43.1%) hydrolase activity (13.7%) "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" QPFTFNFK root GLDVMDAFDQLDVLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.2.19 (100%) rhamnulose-1-phosphate aldolase (100%) GO:0019323 (33.3%) GO:0005829 (33.3%) "GO:0016832 (20.4%) GO:0008994 (13%)" pentose catabolic process (33.3%) cytosol (33.3%) "aldehyde-lyase activity (20.4%) rhamnulose-1-phosphate aldolase activity (13%)" "IPR001303 (33.3%) IPR036409 (33.3%) IPR050197 (33.3%)" "Class II aldolase/adducin N-terminal (33.3%) Class II aldolase/adducin N-terminal domain superfamily (33.3%) Aldolase class II family, sugar metabolism enzymes (33.3%)" LAPASLPSWLSVPSLDAPLDEER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004180 (100%) carboxypeptidase activity (100%) IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) DCYTEGPWFMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.6%) "GO:0004553 (33.6%) GO:0030246 (32.8%)" carbohydrate metabolic process (33.6%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.6%) carbohydrate binding (32.8%)" "IPR006710 (12.9%) IPR005084 (12.6%) IPR006584 (12.6%)" "Glycoside hydrolase, family 43 (12.9%) Carbohydrate binding module family 6 (12.6%) Cellulose binding, type IV (12.6%)" QNTGNFNNNSSWGSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TGGCLEVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (66.7%) IPR011047 (27.8%) IPR011044 (5.6%)" "WD40/YVTN repeat-like-containing domain superfamily (66.7%) Quinoprotein alcohol dehydrogenase-like superfamily (27.8%) Quinoprotein amine dehydrogenase, beta chain-like (5.6%)" DAVHDASVKDYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030245 (24.4%) GO:0000272 (1.3%)" "GO:0005576 (24.4%) GO:0009986 (24.4%)" "GO:0008422 (24.4%) GO:0004553 (1.3%)" "cellulose catabolic process (24.4%) polysaccharide catabolic process (1.3%)" "extracellular region (24.4%) cell surface (24.4%)" "beta-glucosidase activity (24.4%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.3%)" "IPR001547 (21.5%) IPR024361 (20.4%) IPR050386 (20.4%)" "Glycoside hydrolase, family 5 (21.5%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (20.4%) Glycosyl Hydrolase 5 (Cellulase A) (20.4%)" SWGEELSLSSTNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MLLENLVDNFNNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR002035 (25.3%) IPR024163 (25.3%) IPR050768 (25.3%)" "von Willebrand factor, type A (25.3%) Aerotolerance regulator, N-terminal (25.3%) UPF0353/GerABKA protein families (25.3%)" SKDYWTAGGLDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001173 (51.9%) IPR029044 (48.1%)" "Glycosyltransferase 2-like (51.9%) Nucleotide-diphospho-sugar transferases (48.1%)" YDDKDPYSCYTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella KGAADELLELAAELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.13 (100%) methionine synthase (100%) "GO:0032259 (14.3%) GO:0046653 (14.3%) GO:0050667 (14.3%)" GO:0005829 (14.3%) "GO:0008270 (14.3%) GO:0008705 (14.3%) GO:0031419 (14.3%)" "methylation (14.3%) tetrahydrofolate metabolic process (14.3%) homocysteine metabolic process (14.3%)" cytosol (14.3%) "zinc ion binding (14.3%) methionine synthase activity (14.3%) cobalamin binding (14.3%)" "IPR000489 (9.3%) IPR003726 (9.3%) IPR003759 (9.3%)" "Pterin-binding domain (9.3%) Homocysteine-binding domain (9.3%) Cobalamin (vitamin B12)-binding module, cap domain (9.3%)" RYEDTGLWLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VDADLLDR root "1.5.3.24 (30.5%) 2.7.7.60 (15.9%) 4.6.1.12 (15.9%)" "sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) (30.5%) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (15.9%) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (15.9%)" "GO:0046653 (5.3%) GO:0006635 (2.7%) GO:0006083 (2%)" "GO:0005737 (6.2%) GO:0005829 (2.7%) GO:0005739 (0.9%)" "GO:0005524 (9.5%) GO:0016887 (6.8%) GO:0051082 (6.6%)" "tetrahydrofolate metabolic process (5.3%) fatty acid beta-oxidation (2.7%) acetate metabolic process (2%)" "cytoplasm (6.2%) cytosol (2.7%) mitochondrion (0.9%)" "ATP binding (9.5%) ATP hydrolysis activity (6.8%) unfolded protein binding (6.6%)" "IPR001404 (4.5%) IPR020568 (4.5%) IPR020575 (4.5%)" "Heat shock protein Hsp90 family (4.5%) Ribosomal protein uS5 domain 2-type superfamily (4.5%) Heat shock protein Hsp90, N-terminal (4.5%)" AEFWGEGLTGYDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" SEFTLSAPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000917 (33.3%) "GO:0005525 (33.3%) GO:0046872 (33.3%)" division septum assembly (33.3%) "GTP binding (33.3%) metal ion binding (33.3%)" "IPR006073 (26.2%) IPR019987 (26.2%) IPR030393 (26.2%)" "GTP binding domain (26.2%) GTP-binding protein, ribosome biogenesis, YsxC (26.2%) EngB-type guanine nucleotide-binding (G) domain (26.2%)" TGQAWNGVLGGDYNSNFTLLDDGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20%) IPR012910 (20%) IPR036942 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" LAQGVKDWTDATLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19.3%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19.3%)" "IPR008183 (17%) IPR018052 (17%) IPR047215 (17%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17%) Aldose 1-epimerase, conserved site (17%) Galactose mutarotase-like (17%)" PGMVVGVR root "GO:0006412 (18%) GO:0042274 (18%)" "GO:0015935 (18%) GO:0005634 (2%) GO:0005840 (2%)" "GO:0003735 (18%) GO:0019843 (18%) GO:0003723 (2%)" "translation (18%) ribosomal small subunit biogenesis (18%)" "small ribosomal subunit (18%) nucleus (2%) ribosome (2%)" "structural constituent of ribosome (18%) rRNA binding (18%) RNA binding (2%)" "IPR036986 (14.5%) IPR001912 (13%) IPR002942 (13%)" "RNA-binding S4 domain superfamily (14.5%) Small ribosomal subunit protein uS4, N-terminal (13%) RNA-binding S4 domain (13%)" LTLALDGYSSCGK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (18.1%) GO:0015949 (17.8%)" "GO:0005829 (17.8%) GO:0005737 (0.3%)" "GO:0005524 (18.1%) GO:0036431 (18.1%) GO:0036430 (9.5%)" "pyrimidine nucleotide metabolic process (18.1%) nucleobase-containing small molecule interconversion (17.8%)" "cytosol (17.8%) cytoplasm (0.3%)" "ATP binding (18.1%) dCMP kinase activity (18.1%) CMP kinase activity (9.5%)" "IPR003136 (33.3%) IPR011994 (33.3%) IPR027417 (33.3%)" "Cytidylate kinase (33.3%) Cytidylate kinase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" AEFKDEDEPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.6%) "GO:0005829 (16.6%) GO:0005737 (0.4%)" "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004824 (16.6%)" lysyl-tRNA aminoacylation (16.6%) "cytosol (16.6%) cytoplasm (0.4%)" "tRNA binding (16.6%) magnesium ion binding (16.6%) lysine-tRNA ligase activity (16.6%)" "IPR002313 (12.1%) IPR004364 (12.1%) IPR004365 (12.1%)" "Lysine-tRNA ligase, class II (12.1%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.1%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.1%)" LAGLGNLSLDNLYLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (25%) GO:0003700 (25%) GO:0005524 (25%)" "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) ATP binding (25%)" "IPR001789 (7.1%) IPR003594 (7.1%) IPR003661 (7.1%)" "Signal transduction response regulator, receiver domain (7.1%) Histidine kinase/HSP90-like ATPase domain (7.1%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.1%)" FPLADLTLNLAPADLRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR000523 (13.5%) IPR004482 (13.5%) IPR045006 (13.5%)" "Magnesium chelatase ChlI-like, catalytic domain (13.5%) Mg chelatase-related protein (13.5%) Magnesium-chelatase subunit ChlI-like (13.5%)" NPEVLFFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.3%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" EAGYRVEQEDVEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.3 (50.7%) 2.7.2.4 (49.3%)" "homoserine dehydrogenase (50.7%) aspartate kinase (49.3%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" GLKDTYSANLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) SGTCWAYSTLSYFESELLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (21%) GO:0009636 (19.4%) GO:0043418 (19.4%)" GO:0005737 (19.4%) GO:0070005 (21%) "proteolysis (21%) response to toxic substance (19.4%) homocysteine catabolic process (19.4%)" cytoplasm (19.4%) cysteine-type aminopeptidase activity (21%) "IPR000169 (32.5%) IPR004134 (32.5%) IPR038765 (30%)" "Cysteine peptidase, cysteine active site (32.5%) Peptidase C1B, bleomycin hydrolase (32.5%) Papain-like cysteine peptidase superfamily (30%)" TGSPTYLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR012547 (49.6%) IPR018631 (48.7%) IPR027417 (1.7%)" "PD-(D/E)XK nuclease superfamily 9 (49.6%) AAA-ATPase-like domain (48.7%) P-loop containing nucleoside triphosphate hydrolase (1.7%)" TLQTGTALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" LVFSSLGYK root 1.18.1.6 (100%) adrenodoxin-NADP(+) reductase (100%) "GO:0044718 (9.1%) GO:0006826 (5%) GO:0007018 (2.5%)" "GO:0009279 (53.7%) GO:0005871 (2.5%) GO:0005874 (2.5%)" "GO:0015344 (9.1%) GO:0003777 (2.5%) GO:0005524 (2.5%)" "siderophore transmembrane transport (9.1%) iron ion transport (5%) microtubule-based movement (2.5%)" "cell outer membrane (53.7%) kinesin complex (2.5%) microtubule (2.5%)" "siderophore uptake transmembrane transporter activity (9.1%) microtubule motor activity (2.5%) ATP binding (2.5%)" "IPR008969 (14.1%) IPR012910 (13.5%) IPR039426 (13.5%)" "Carboxypeptidase-like, regulatory domain superfamily (14.1%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent receptor-like (13.5%)" QGFANEALAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 4.3.2.10 (100%) imidazole glycerol-phosphate synthase (100%) GO:0000105 (25%) GO:0005737 (25%) "GO:0000107 (25%) GO:0016829 (25%)" L-histidine biosynthetic process (25%) cytoplasm (25%) "imidazoleglycerol-phosphate synthase activity (25%) lyase activity (25%)" "IPR004651 (20.3%) IPR006062 (20.3%) IPR050064 (20.3%)" "Histidine biosynthesis, HisF (20.3%) Histidine biosynthesis protein (20.3%) Imidazole glycerol phosphate synthase HisA/HisF (20.3%)" LNVVLLDFDEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (23.6%) IPR012340 (23.6%) IPR035104 (23.6%)" "S1 domain (23.6%) Nucleic acid-binding, OB-fold (23.6%) Ribosomal protein S1-like (23.6%)" DMVLASPDVGGSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.2%) GO:0006164 (11.2%) GO:0009156 (10.8%)" "GO:0002189 (11.2%) GO:0005737 (11.2%)" "GO:0000287 (11.2%) GO:0004749 (11.2%) GO:0005524 (11.2%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.2%) purine nucleotide biosynthetic process (11.2%) ribonucleoside monophosphate biosynthetic process (10.8%)" "ribose phosphate diphosphokinase complex (11.2%) cytoplasm (11.2%)" "magnesium ion binding (11.2%) ribose phosphate diphosphokinase activity (11.2%) ATP binding (11.2%)" "IPR000836 (18.7%) IPR005946 (18.7%) IPR029057 (18.7%)" "Phosphoribosyltransferase domain (18.7%) Ribose-phosphate pyrophosphokinase (18.7%) Phosphoribosyltransferase-like (18.7%)" ELYTLLSDHSHTPYDKVYADSDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.92 (100%) endopeptidase Clp (100%) GO:0006515 (16.7%) "GO:0005737 (16.7%) GO:0009368 (16.7%)" "GO:0004176 (16.7%) GO:0004252 (16.7%) GO:0051117 (16.7%)" protein quality control for misfolded or incompletely synthesized proteins (16.7%) "cytoplasm (16.7%) endopeptidase Clp complex (16.7%)" "ATP-dependent peptidase activity (16.7%) serine-type endopeptidase activity (16.7%) ATPase binding (16.7%)" "IPR001907 (25%) IPR023562 (25%) IPR029045 (25%)" "ATP-dependent Clp protease proteolytic subunit (25%) Clp protease proteolytic subunit /Translocation-enhancing protein TepA (25%) ClpP/crotonase-like domain superfamily (25%)" NYEPLNTAEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (15.4%) IPR012910 (15.4%) IPR023997 (15.4%)" "Carboxypeptidase-like, regulatory domain superfamily (15.4%) TonB-dependent receptor, plug domain (15.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.4%)" QKVEVAEEYFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR032816 (50%) IPR051311 (50%)" "VTT domain (50%) DedA domain-containing protein (50%)" WAADHVLETLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0005975 (14.3%) GO:0006043 (14.3%) GO:0006046 (14.3%)" "GO:0005829 (12.9%) GO:0005737 (1.4%)" "GO:0004342 (14.3%) GO:0042802 (14.3%)" "carbohydrate metabolic process (14.3%) glucosamine catabolic process (14.3%) N-acetylglucosamine catabolic process (14.3%)" "cytosol (12.9%) cytoplasm (1.4%)" "glucosamine-6-phosphate deaminase activity (14.3%) identical protein binding (14.3%)" "IPR004547 (25.6%) IPR006148 (25.6%) IPR018321 (25.6%)" "Glucosamine-6-phosphate isomerase (25.6%) Glucosamine/galactosamine-6-phosphate isomerase (25.6%) Glucosamine-6-phosphate isomerase, conserved site (25.6%)" EGTPLSYR root "1.11.1.6 (71.4%) 2.7.1.17 (28.6%)" "catalase (71.4%) xylulokinase (28.6%)" "GO:0005975 (31.1%) GO:0042542 (6.4%) GO:0042744 (6.4%)" GO:0005737 (6.4%) "GO:0016301 (31.1%) GO:0004096 (6.4%) GO:0020037 (6.4%)" "carbohydrate metabolic process (31.1%) response to hydrogen peroxide (6.4%) hydrogen peroxide catabolic process (6.4%)" cytoplasm (6.4%) "kinase activity (31.1%) catalase activity (6.4%) heme binding (6.4%)" "IPR018484 (16%) IPR018485 (16%) IPR050406 (16%)" "Carbohydrate kinase FGGY, N-terminal (16%) Carbohydrate kinase FGGY, C-terminal (16%) FGGY Carbohydrate Kinase (16%)" MVVDTLDNLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (100%) cytosol (100%) "IPR004375 (51.2%) IPR037012 (48.8%)" "NanQ anomerase/TabA/YiaL family (51.2%) NanQ anomerase/TabA/YiaL superfamily (48.8%)" WFEYWQERPGTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (10.1%) IPR006103 (10.1%) IPR006104 (10.1%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (10.1%) Glycoside hydrolase family 2, catalytic domain (10.1%) Glycosyl hydrolases family 2, sugar binding domain (10.1%)" FVTLLNETGDPDKALDGLFECLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005829 (50%) GO:0004834 (50%) cytosol (50%) tryptophan synthase activity (50%) "IPR002028 (25%) IPR011060 (25%) IPR013785 (25%)" "Tryptophan synthase, alpha chain (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" QQMLVYGYGTANPDPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VSVPEAELSHLHVGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" MATGSWAANNDPMSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VGAGPFPTELFDETGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" AALLRPLEK root "4.2.1.51 (90%) 5.6.2.4 (10%)" "prephenate dehydratase (90%) DNA 3'-5' helicase (10%)" "GO:0009094 (22.6%) GO:0006269 (2.4%) GO:0006270 (2.4%)" "GO:0005737 (22.6%) GO:1990077 (2.4%)" "GO:0004664 (22.6%) GO:0003677 (2.4%) GO:0005524 (2.4%)" "L-phenylalanine biosynthetic process (22.6%) DNA replication, synthesis of primer (2.4%) DNA replication initiation (2.4%)" "cytoplasm (22.6%) primosome complex (2.4%)" "prephenate dehydratase activity (22.6%) DNA binding (2.4%) ATP binding (2.4%)" "IPR002912 (19.4%) IPR001086 (18.4%) IPR045865 (18.4%)" "ACT domain (19.4%) Prephenate dehydratase (18.4%) ACT-like domain (18.4%)" LSVGGYGEVAMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR023614 (100%) Porin domain superfamily (100%) SYANSNHPDLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" VTGLDDGEEQTVLDFGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030246 (100%) carbohydrate binding (100%) "IPR041700 (84.8%) IPR008969 (13%) IPR013784 (2.2%)" "Outer membrane protein beta-barrel domain 3 (84.8%) Carboxypeptidase-like, regulatory domain superfamily (13%) Carbohydrate-binding-like fold (2.2%)" DNYGNDAAGNTTLDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008160 (50%) IPR032149 (50%)" "Collagen triple helix repeat (50%) Domain of unknown function DUF4988 (50%)" NNLLNLNFTYLDGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella LGSLLNAPNTCAPTAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (12.9%) IPR051915 (12.9%) IPR002772 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (12.9%) Cellulose Degradation Glycosyl Hydrolase 3 (12.9%) Glycoside hydrolase family 3 C-terminal domain (12.5%)" LHMLFETAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.4.1.13 (97.4%) 1.4.-.- (2.6%)" "glutamate synthase (NADPH) (97.4%) Acting on the CH-NH2 group of donors (2.6%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.4%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.4%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" LAALETNHTLGVLNDELSGALGQACR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006099 (25%) GO:0006531 (25%)" GO:0005829 (25%) GO:0008797 (25%) "tricarboxylic acid cycle (25%) aspartate metabolic process (25%)" cytosol (25%) aspartate ammonia-lyase activity (25%) "IPR018951 (15.6%) IPR020557 (15.6%) IPR022761 (15.6%)" "Fumarase C, C-terminal (15.6%) Fumarate lyase, conserved site (15.6%) Fumarate lyase, N-terminal (15.6%)" AKDTYQVTHLLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25%) "GO:0005525 (25%) GO:0015093 (25%) GO:0046914 (25%)" plasma membrane (25%) "GTP binding (25%) ferrous iron transmembrane transporter activity (25%) transition metal ion binding (25%)" "IPR003373 (9.1%) IPR005225 (9.1%) IPR007167 (9.1%)" "Ferrous iron transport protein B (9.1%) Small GTP-binding domain (9.1%) Ferrous iron transporter FeoA-like domain (9.1%)" TLAGEEVALNPLWDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (31.7%) "GO:0030170 (34.1%) GO:0010285 (31.7%) GO:0008483 (2.4%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (31.7%) "pyridoxal phosphate binding (34.1%) L,L-diaminopimelate aminotransferase activity (31.7%) transaminase activity (2.4%)" "IPR004839 (22.2%) IPR019942 (22.2%) IPR015421 (19%)" "Aminotransferase, class I/classII, large domain (22.2%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (22.2%) Pyridoxal phosphate-dependent transferase, major domain (19%)" NAQYHYPVYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.2%) IPR011990 (33.3%) IPR033985 (31.5%)" "RagB/SusD domain (35.2%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (31.5%)" DGGGAGASLYATSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.47 (100%) glucose 1-dehydrogenase [NAD(P)(+)] (100%) GO:0016491 (100%) oxidoreductase activity (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" FENYGLTR root "GO:0016020 (94.1%) GO:0005886 (5.9%)" "membrane (94.1%) plasma membrane (5.9%)" "IPR025736 (16.7%) IPR041522 (16.7%) IPR042070 (16.7%)" "PucR C-terminal helix-turn-helix domain (16.7%) CdaR, GGDEF-like domain (16.7%) PucR C-terminal helix-turn-helix domain superfamily (16.7%)" HYMHDHFPNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (26.2%) IPR025997 (26.2%) IPR010982 (23.8%)" "LacI-type HTH domain (26.2%) Periplasmic binding protein (26.2%) Lambda repressor-like, DNA-binding domain superfamily (23.8%)" AQELYAQNPQAAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (96.7%) 3.4.13.- (3.3%)" "Acting on peptide bonds (peptidases) (96.7%) Dipeptidases (3.3%)" GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) LLLPECQMEVPTTHDLTTELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) KSAAFDFQFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (36.1%) "GO:0004556 (32%) GO:0043169 (32%)" carbohydrate metabolic process (36.1%) "alpha-amylase activity (32%) cation binding (32%)" "IPR006047 (28.2%) IPR017853 (26.9%) IPR006046 (25%)" "Glycosyl hydrolase family 13, catalytic domain (28.2%) Glycoside hydrolase superfamily (26.9%) Alpha amylase (25%)" LQTVLDGETVKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (57.1%) 1.6.5.9 (42.9%)" "Transferred entry: 1.6.5.9 (57.1%) NADH:ubiquinone reductase (non-electrogenic) (42.9%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (19.7%) IPR001268 (19.7%) IPR022885 (19.7%)" "NADH-quinone oxidoreductase, subunit D (19.7%) NADH:ubiquinone oxidoreductase, 30kDa subunit (19.7%) NAD(P)H-quinone oxidoreductase subunit D/H (19.7%)" DHCDVNDFMALLSPAAEPYLEVMAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009228 (25%) "GO:0003824 (25%) GO:0005506 (25%) GO:0051539 (25%)" thiamine biosynthetic process (25%) "catalytic activity (25%) iron ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR007197 (20.3%) IPR010722 (20.3%) IPR012726 (20.3%)" "Radical SAM (20.3%) Biotin and thiamin synthesis-associated domain (20.3%) Thiazole biosynthesis ThiH (20.3%)" DVAVDWDKSLYLEAEPMEYLTAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (50.7%) GO:0016787 (49.3%)" "carbohydrate binding (50.7%) hydrolase activity (49.3%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" DNNLFVTDGDKETQLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.-.- (50%) 3.4.14.5 (50%)" "Acting on peptide bonds (peptidases) (50%) dipeptidyl-peptidase IV (50%)" GO:0006508 (34.1%) "GO:0008239 (34.1%) GO:0008236 (31.8%)" proteolysis (34.1%) "dipeptidyl-peptidase activity (34.1%) serine-type peptidase activity (31.8%)" "IPR002469 (26.1%) IPR050278 (26.1%) IPR001375 (24.3%)" "Dipeptidylpeptidase IV, N-terminal domain (26.1%) Serine protease S9B/DPPIV (26.1%) Peptidase S9, prolyl oligopeptidase, catalytic domain (24.3%)" LTVEDFPAFLLVDDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.9%) "GO:0046872 (24.9%) GO:0051539 (24.9%) GO:0004333 (24.1%)" tricarboxylic acid cycle (24.9%) "metal ion binding (24.9%) 4 iron, 4 sulfur cluster binding (24.9%) fumarate hydratase activity (24.1%)" "IPR004647 (18.5%) IPR051208 (18.5%) IPR004646 (18.2%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.5%) Class-I Fumarase/Tartrate Dehydratase (18.5%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.2%)" ALTMVPFNVDAEDMVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (13.9%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (13.9%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" NQELLDEGFLALFR Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.6%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.6%)" "IPR000185 (8.1%) IPR011115 (8.1%) IPR014001 (8.1%)" "Protein translocase subunit SecA (8.1%) SecA DEAD-like, N-terminal (8.1%) Helicase superfamily 1/2, ATP-binding domain (8.1%)" NVMTVLNGK root GO:0005975 (49.1%) "GO:0016798 (49.1%) GO:0008270 (1.8%)" carbohydrate metabolic process (49.1%) "hydrolase activity, acting on glycosyl bonds (49.1%) zinc ion binding (1.8%)" "IPR006047 (14.3%) IPR015171 (14.3%) IPR019492 (14.3%)" "Glycosyl hydrolase family 13, catalytic domain (14.3%) Cyclomaltodextrinase, N-terminal (14.3%) Cyclo-malto-dextrinase, C-terminal (14.3%)" LYFHQQLLNDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.9%) GO:0006529 (1.1%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (23.9%) GO:0000166 (1.1%)" "L-asparagine biosynthetic process (23.9%) obsolete asparagine biosynthetic process (1.1%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (23.9%) nucleotide binding (1.1%)" "IPR004618 (33.8%) IPR006195 (33.8%) IPR045864 (32.3%)" "Aspartate--ammonia ligase (33.8%) Aminoacyl-tRNA synthetase, class II (33.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (32.3%)" NDGHNYLPELYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.1.1 (100%) alanine racemase (100%) "GO:0030632 (19.5%) GO:0008360 (0.4%) GO:0009252 (0.4%)" "GO:0005524 (19.9%) GO:0008784 (19.5%) GO:0016881 (19.5%)" "D-alanine biosynthetic process (19.5%) regulation of cell shape (0.4%) peptidoglycan biosynthetic process (0.4%)" "ATP binding (19.9%) alanine racemase activity (19.5%) acid-amino acid ligase activity (19.5%)" "IPR013221 (10.3%) IPR051046 (10.3%) IPR000821 (10.1%)" "Mur ligase, central (10.3%) MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.3%) Alanine racemase (10.1%)" QLNDGVALFSHLYDEWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella LFLAPGNAGTQNVGENVDLKADDFEALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0006189 (20%) GO:0009113 (20%)" "GO:0004637 (20%) GO:0005524 (20%) GO:0046872 (20%)" "'de novo' IMP biosynthetic process (20%) purine nucleobase biosynthetic process (20%)" "phosphoribosylamine-glycine ligase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000115 (11.5%) IPR011761 (11.5%) IPR020560 (11.5%)" "Phosphoribosylglycinamide synthetase (11.5%) ATP-grasp fold (11.5%) Phosphoribosylglycinamide synthetase, C-domain (11.5%)" NNFVLEFLDYYLDPPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (19.8%) GO:0006508 (0.6%)" GO:0000428 (19.9%) "GO:0003899 (19.8%) GO:0003677 (19.8%) GO:0032549 (19.5%)" "DNA-templated transcription (19.8%) proteolysis (0.6%)" DNA-directed RNA polymerase complex (19.9%) "DNA-directed RNA polymerase activity (19.8%) DNA binding (19.8%) ribonucleoside binding (19.5%)" "IPR007644 (8.1%) IPR007642 (8%) IPR015712 (8%)" "RNA polymerase, beta subunit, protrusion (8.1%) RNA polymerase Rpb2, domain 2 (8%) DNA-directed RNA polymerase, subunit 2 (8%)" YFDTYFTQGPYFTSHFEALAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (33.9%) IPR051612 (33.9%) IPR043148 (32.1%)" "CDP-glycerol glycerophosphotransferase (33.9%) Teichoic Acid Biosynthesis Enzymes (33.9%) CDP-glycerol glycerophosphotransferase, C-terminal domain (32.1%)" MNFPLFLAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" AFLGPEVEAEWDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.5%) IPR006512 (25.5%) IPR050144 (25.5%)" "Regulator of K+ conductance, C-terminal (25.5%) YidE/YbjL duplication (25.5%) AAE Transporter (25.5%)" NLGFGTLLSLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0003677 (100%) DNA binding (100%) "IPR001387 (50%) IPR010982 (50%)" "Cro/C1-type, helix-turn-helix domain (50%) Lambda repressor-like, DNA-binding domain superfamily (50%)" EHGALLYYDLNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) "IPR002173 (25%) IPR011611 (25%) IPR029056 (25%)" "Carbohydrate/purine kinase, PfkB, conserved site (25%) Carbohydrate kinase PfkB (25%) Ribokinase-like (25%)" VVAGVGVPQLSAVYDVYSALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20.1%) GO:0006183 (20.1%)" "GO:0003938 (20.1%) GO:0046872 (20.1%) GO:0000166 (19.6%)" "GMP biosynthetic process (20.1%) GTP biosynthetic process (20.1%)" "IMP dehydrogenase activity (20.1%) metal ion binding (20.1%) nucleotide binding (19.6%)" "IPR000644 (16.9%) IPR001093 (16.9%) IPR005990 (16.9%)" "CBS domain (16.9%) IMP dehydrogenase/GMP reductase (16.9%) Inosine-5'-monophosphate dehydrogenase (16.9%)" LVPQLAEEGTAHELLEQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009307 (33.3%) "GO:0003677 (33.3%) GO:0004519 (33.3%)" DNA restriction-modification system (33.3%) "DNA binding (33.3%) endonuclease activity (33.3%)" "IPR000055 (33.3%) IPR044946 (33.3%) IPR051212 (33.3%)" "Type I restriction modification DNA specificity domain (33.3%) Type I restriction modification DNA specificity domain superfamily (33.3%) Type I restriction enzyme S subunit (33.3%)" AAEEAPAEEAPAEA Bacteria Bacteria GO:0006412 (20.8%) "GO:0005737 (20.8%) GO:0015935 (20.8%) GO:0016020 (4.2%)" "GO:0003735 (20.8%) GO:0009055 (4.2%) GO:0020037 (4.2%)" translation (20.8%) "cytoplasm (20.8%) small ribosomal subunit (20.8%) membrane (4.2%)" "structural constituent of ribosome (20.8%) electron transfer activity (4.2%) heme binding (4.2%)" "IPR000307 (37%) IPR023803 (37%) IPR009056 (7.4%)" "Small ribosomal subunit protein bS16 (37%) Small ribosomal subunit protein bS16 domain superfamily (37%) Cytochrome c-like domain (7.4%)" NFEANLPLGFFCYPVSQAADLTAFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" YGNMDHWVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0016798 (50%) xylan catabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR025112 (51.9%) IPR038653 (48.1%)" "Putative carbohydrate metabolism domain (51.9%) Putative carbohydrate metabolism domain superfamily (48.1%)" AVPVYNLDGYFMK Pseudomonadati Bacteria Pseudomonadati 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.6%) IPR050309 (20.6%) IPR019819 (19.6%)" "Carboxylesterase, type B (20.6%) Type-B Carboxylesterase/Lipase (20.6%) Carboxylesterase type B, conserved site (19.6%)" LVDRGEVLTNNTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (96.4%) GO:0016787 (3.6%) membrane (96.4%) hydrolase activity (3.6%) "IPR003607 (16.8%) IPR006674 (16.8%) IPR006675 (16.8%)" "HD/PDEase domain (16.8%) HD domain (16.8%) HDIG domain (16.8%)" MQVSALELK root 7.2.2.10 (100%) P-type Ca(2+) transporter (100%) "GO:0006508 (0.5%) GO:0006915 (0.5%)" "GO:0005886 (19.7%) GO:0012505 (19.7%)" "GO:0005388 (19.7%) GO:0005524 (19.7%) GO:0016887 (19.7%)" "proteolysis (0.5%) apoptotic process (0.5%)" "plasma membrane (19.7%) endomembrane system (19.7%)" "P-type calcium transporter activity (19.7%) ATP binding (19.7%) ATP hydrolysis activity (19.7%)" "IPR001757 (9.2%) IPR004014 (9.2%) IPR006068 (9.2%)" "P-type ATPase (9.2%) Cation-transporting P-type ATPase, N-terminal (9.2%) Cation-transporting P-type ATPase, C-terminal (9.2%)" KTGLQPDLTVLVVTLQALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) GO:0035999 (33.3%) "GO:0004329 (33.3%) GO:0005524 (33.3%)" tetrahydrofolate interconversion (33.3%) "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.1%) IPR020628 (34.1%) IPR027417 (31.9%)" "Formate-tetrahydrofolate ligase, FTHFS (34.1%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (34.1%) P-loop containing nucleoside triphosphate hydrolase (31.9%)" SAFSQANLQDVVWSQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026906 (33.3%) IPR032675 (33.3%) IPR053139 (33.3%)" "BspA-type LRR region (33.3%) Leucine-rich repeat domain superfamily (33.3%) Putative surface bspA-like protein (33.3%)" DFLVPAFVLLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0030435 (97.5%) GO:0016740 (2.5%) sporulation resulting in formation of a cellular spore (97.5%) transferase activity (2.5%) "IPR001173 (12.7%) IPR013486 (12.7%) IPR013693 (12.7%)" "Glycosyltransferase 2-like (12.7%) Sporulation stage II protein D, amidase enhancer LytB (12.7%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.7%)" GPGAHLLLDK Bacteria Bacteria 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (50%) IPR029052 (50%)" "Fructose-1,6-bisphosphatase class 3 (50%) Metallo-dependent phosphatase-like (50%)" LSLGLEDVDDLFEDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0019346 (20%) GO:0005737 (20%) "GO:0016846 (20%) GO:0030170 (20%) GO:0016740 (14.1%)" transsulfuration (20%) cytoplasm (20%) "carbon-sulfur lyase activity (20%) pyridoxal phosphate binding (20%) transferase activity (14.1%)" "IPR000277 (25%) IPR015421 (25%) IPR015422 (25%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (25%) Pyridoxal phosphate-dependent transferase, major domain (25%) Pyridoxal phosphate-dependent transferase, small domain (25%)" DDFWNYLNQDSYLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (32.5%) GO:0009279 (35%) GO:0015344 (32.5%) siderophore transmembrane transport (32.5%) cell outer membrane (35%) siderophore uptake transmembrane transporter activity (32.5%) "IPR057601 (21.9%) IPR036942 (20.3%) IPR039426 (20.3%)" "TonB-dependent transporter Oar-like, beta-barrel domain (21.9%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.3%) TonB-dependent receptor-like (20.3%)" NAALVHNLNECEDLTCYPVTDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.9 (100%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (100%) GO:0009234 (20.3%) "GO:0030976 (21.8%) GO:0070204 (20.3%) GO:0000287 (18.8%)" menaquinone biosynthetic process (20.3%) "thiamine pyrophosphate binding (21.8%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (20.3%) magnesium ion binding (18.8%)" "IPR012001 (26.9%) IPR004433 (25%) IPR029061 (25%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (26.9%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (25%) Thiamin diphosphate-binding fold (25%)" GLQEEKLETLFQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (0.7%) "GO:0000155 (25.2%) GO:0005524 (25.2%) GO:0003700 (24.5%)" membrane (0.7%) "phosphorelay sensor kinase activity (25.2%) ATP binding (25.2%) DNA-binding transcription factor activity (24.5%)" "IPR001789 (7.5%) IPR003594 (7.5%) IPR005467 (7.5%)" "Signal transduction response regulator, receiver domain (7.5%) Histidine kinase/HSP90-like ATPase domain (7.5%) Histidine kinase domain (7.5%)" DLSYSLR root "2.7.7.6 (46%) 2.1.1.355 (18.4%) 2.7.10.1 (14.7%)" "DNA-directed RNA polymerase (46%) [histone H3]-lysine(9) N-trimethyltransferase (18.4%) receptor protein-tyrosine kinase (14.7%)" "GO:0007156 (4%) GO:0016339 (3.3%) GO:0000902 (3.2%)" "GO:0005912 (3.2%) GO:0016342 (3.2%) GO:0005886 (2%)" "GO:0008270 (4.2%) GO:0005509 (4%) GO:0008013 (3.2%)" "homophilic cell-cell adhesion (4%) calcium-dependent cell-cell adhesion (3.3%) cell morphogenesis (3.2%)" "adherens junction (3.2%) catenin complex (3.2%) plasma membrane (2%)" "zinc ion binding (4.2%) calcium ion binding (4%) beta-catenin binding (3.2%)" "IPR002126 (3.7%) IPR015919 (3.7%) IPR020894 (3.7%)" "Cadherin-like (3.7%) Cadherin-like superfamily (3.7%) Cadherin conserved site (3.7%)" GAAGYSEYFVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) LDKLAQTCVFTSQGVPFLLAGEEMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50%) "GO:0016798 (43.2%) GO:0051060 (6.8%)" carbohydrate metabolic process (50%) "hydrolase activity, acting on glycosyl bonds (43.2%) pullulanase activity (6.8%)" "IPR006047 (14.6%) IPR011840 (14.6%) IPR017853 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (14.6%) Pullulanase, type I (14.6%) Glycoside hydrolase superfamily (14.6%)" AELLPTDKVSHVEQLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) "GO:0005886 (16.3%) GO:0016020 (0.6%)" "GO:0005524 (16.9%) GO:0015086 (16.9%) GO:0016887 (16.9%)" "plasma membrane (16.3%) membrane (0.6%)" "ATP binding (16.9%) cadmium ion transmembrane transporter activity (16.9%) ATP hydrolysis activity (16.9%)" "IPR001757 (10.4%) IPR051014 (10.4%) IPR018303 (10%)" "P-type ATPase (10.4%) Cation Transport ATPase Type IB (10.4%) P-type ATPase, phosphorylation site (10%)" GEEELSMDDLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (22.3%) IPR003379 (22.3%) IPR055268 (22.3%)" "Pyruvate carboxyltransferase (22.3%) Carboxylase, conserved domain (22.3%) Pyruvate carboxylase-like (22.3%)" DGCQWWNRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.8%) IPR003385 (20.8%) IPR013783 (19.5%)" "Carbohydrate binding module family 20 (20.8%) Glycoside hydrolase, family 77 (20.8%) Immunoglobulin-like fold (19.5%)" NVNLQMLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR000595 (34.9%) IPR014710 (32.6%) IPR018490 (32.6%)" "Cyclic nucleotide-binding domain (34.9%) RmlC-like jelly roll fold (32.6%) Cyclic nucleotide-binding domain superfamily (32.6%)" ELGADALAHGSTGAGNDQLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.5%) IPR048267 (14.5%) IPR014729 (14.4%)" "Argininosuccinate synthase (14.5%) Arginosuccinate synthase-like, N-terminal domain (14.5%) Rossmann-like alpha/beta/alpha sandwich fold (14.4%)" NANSASFSGADAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" LGNNNEFFPGASLSTKPQDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (30.9%) GO:0008610 (3.6%)" GO:0016020 (30.9%) GO:0008780 (34.5%) "lipid A biosynthetic process (30.9%) lipid biosynthetic process (3.6%)" membrane (30.9%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.5%) "IPR010137 (20.7%) IPR011004 (20.7%) IPR001451 (19.6%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.7%) Trimeric LpxA-like superfamily (20.7%) Hexapeptide repeat (19.6%)" NNFYYAWGDLDLNELRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009313 (16.7%) GO:0043039 (16.7%)" "GO:0004556 (16.7%) GO:0004812 (16.7%) GO:0005524 (16.7%)" "oligosaccharide catabolic process (16.7%) tRNA aminoacylation (16.7%)" "alpha-amylase activity (16.7%) aminoacyl-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR006047 (25%) IPR012947 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Threonyl/alanyl tRNA synthetase, SAD (25%) Glycoside hydrolase superfamily (25%)" GLYSSPFDAFTNYMNLLGDFLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (50%) "GO:0003824 (34.6%) GO:0016787 (11.5%) GO:0004556 (3.8%)" carbohydrate metabolic process (50%) "catalytic activity (34.6%) hydrolase activity (11.5%) alpha-amylase activity (3.8%)" "IPR004300 (33.8%) IPR052046 (33.8%) IPR011330 (32.5%)" "Glycoside hydrolase family 57, N-terminal domain (33.8%) Glycosyl hydrolase family 57 (33.8%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.5%)" GLAQLATK root "6.-.-.- (28.6%) 2.3.2.27 (14.3%) 2.4.1.25 (14.3%)" "Ligases (28.6%) RING-type E3 ubiquitin transferase (14.3%) 4-alpha-glucanotransferase (14.3%)" "GO:0015977 (17.6%) GO:0006633 (3.1%) GO:0009307 (1%)" "GO:0009317 (17.6%) GO:0016020 (1.7%) GO:0005886 (0.7%)" "GO:0004658 (18.3%) GO:0003989 (17.6%) GO:0016740 (7.6%)" "carbon fixation (17.6%) fatty acid biosynthetic process (3.1%) DNA restriction-modification system (1%)" "acetyl-CoA carboxylase complex (17.6%) membrane (1.7%) plasma membrane (0.7%)" "propionyl-CoA carboxylase activity (18.3%) acetyl-CoA carboxylase activity (17.6%) transferase activity (7.6%)" "IPR034733 (15.4%) IPR051047 (15.4%) IPR011763 (15.1%)" "Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (15.4%) Acyl-CoA Carboxylase Beta Subunit (15.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (15.1%)" LNNVETLAQVFTDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016491 (100%) oxidoreductase activity (100%) "IPR016446 (33.7%) IPR029479 (33.7%) IPR000415 (32.5%)" "Flavin oxidoreductase Frp family (33.7%) Nitroreductase (33.7%) Nitroreductase-like (32.5%)" LSSLLTNDGYFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000184 (50%) IPR039910 (50%)" "Bacterial surface antigen (D15) (50%) Surface antigen D15-like (50%)" HDYTFQSDELKLDYLDSLEFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" ASCYNAQTMEGVQALVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20%) GO:0008615 (20%)" GO:0005737 (20%) "GO:0004648 (20%) GO:0030170 (20%)" "L-serine biosynthetic process (20%) pyridoxine biosynthetic process (20%)" cytoplasm (20%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20%) pyridoxal phosphate binding (20%)" "IPR000192 (20%) IPR015421 (20%) IPR015422 (20%)" "Aminotransferase class V domain (20%) Pyridoxal phosphate-dependent transferase, major domain (20%) Pyridoxal phosphate-dependent transferase, small domain (20%)" VQAVHAGLECSLLLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.3%) IPR002933 (33.3%) IPR011650 (33.3%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (33.3%) Peptidase M20, dimerisation domain (33.3%)" SFFYLSEQDGTFNLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.2%) IPR011659 (14.2%) IPR012393 (14.2%)" "Tail specific protease (14.2%) WD40-like beta-propeller (14.2%) Tricorn protease (14.2%)" LALNEALDFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006352 (33%) "GO:0003677 (33%) GO:0016987 (33%) GO:0003899 (0.9%)" DNA-templated transcription initiation (33%) "DNA binding (33%) sigma factor activity (33%) DNA-directed RNA polymerase activity (0.9%)" "IPR007627 (12.7%) IPR013249 (12.7%) IPR013324 (12.7%)" "RNA polymerase sigma-70 region 2 (12.7%) RNA polymerase sigma factor 70, region 4 type 2 (12.7%) RNA polymerase sigma factor, region 3/4-like (12.7%)" SKLPDGLPGLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.2.1.22 (97.2%) 3.2.1.- (2.8%)" "alpha-galactosidase (97.2%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.8%)" GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (13%) IPR050985 (13%) IPR013785 (12.6%)" "Glycoside hydrolase family 36 (13%) Alpha-glycosidase and related enzymes (13%) Aldolase-type TIM barrel (12.6%)" SLGNMTLNCNVSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) FLGNYSSGK Bacteria Bacteria "6.3.2.5 (50%) 4.1.1.36 (50%)" "phosphopantothenate--cysteine ligase (CTP) (50%) phosphopantothenoylcysteine decarboxylase (50%)" "GO:0015937 (14.4%) GO:0015941 (14.3%)" "GO:0071513 (14.2%) GO:0016020 (0.2%)" "GO:0004632 (14.3%) GO:0004633 (14.3%) GO:0010181 (14.3%)" "coenzyme A biosynthetic process (14.4%) pantothenate catabolic process (14.3%)" "phosphopantothenoylcysteine decarboxylase complex (14.2%) membrane (0.2%)" "phosphopantothenate--cysteine ligase activity (14.3%) phosphopantothenoylcysteine decarboxylase activity (14.3%) FMN binding (14.3%)" "IPR007085 (20.1%) IPR005252 (20.1%) IPR035929 (20%)" "DNA/pantothenate metabolism flavoprotein, C-terminal (20.1%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.1%) CoaB-like superfamily (20%)" NLVPGLEYEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0016989 (50%) membrane (50%) sigma factor antagonist activity (50%) "IPR032508 (35.3%) IPR006860 (32.4%) IPR012373 (32.4%)" "Protein FecR, C-terminal (35.3%) FecR protein (32.4%) Fe(2+)-dicitrate sensor, transmembrane component (32.4%)" NLYDTDDAFFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MKLPFGLCQLGK Bacteria Bacteria 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0070062 (12.5%) GO:1990742 (12.5%) GO:0005737 (11.8%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "extracellular exosome (12.5%) microvesicle (12.5%) cytoplasm (11.8%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR006195 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Aminoacyl-tRNA synthetase, class II (11.3%)" SGDLGSFLKPGTFEPATSETSVLGSVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (100%) carbohydrate metabolic process (100%) "IPR028028 (37.5%) IPR008928 (31.3%) IPR012341 (31.3%)" "Protein of unknown function DUF4450 (37.5%) Six-hairpin glycosidase superfamily (31.3%) Six-hairpin glycosidase-like superfamily (31.3%)" ALVDTEDERFYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.7%) GO:0016020 (0.5%)" "GO:0008955 (11.3%) GO:0008658 (11%) GO:0004180 (10.7%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.7%) membrane (0.5%)" "peptidoglycan glycosyltransferase activity (11.3%) penicillin binding (11%) carboxypeptidase activity (10.7%)" "IPR001264 (17.2%) IPR050396 (17.2%) IPR001460 (16.7%)" "Glycosyl transferase, family 51 (17.2%) Glycosyltransferase 51/Transpeptidase (17.2%) Penicillin-binding protein, transpeptidase (16.7%)" DVEFLDMTSSSGSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016301 (51.2%) GO:0005524 (48.8%)" "kinase activity (51.2%) ATP binding (48.8%)" "IPR006083 (34.4%) IPR018163 (32.8%) IPR027417 (32.8%)" "Phosphoribulokinase/uridine kinase (34.4%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (32.8%) P-loop containing nucleoside triphosphate hydrolase (32.8%)" QLDRNEVTVDQFTGWMQWAK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.8%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.8%)" EMYHQPCAADGNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) NWTFENQTPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR001179 (50%) IPR046357 (50%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (50%) Peptidyl-prolyl cis-trans isomerase domain superfamily (50%)" GMDEEQLAHVFDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) "GO:0000160 (13%) GO:0007234 (12.2%)" GO:0016020 (25.2%) "GO:0016301 (25.2%) GO:0000156 (12.2%) GO:0030295 (12.2%)" "phosphorelay signal transduction system (13%) osmosensory signaling via phosphorelay pathway (12.2%)" membrane (25.2%) "kinase activity (25.2%) phosphorelay response regulator activity (12.2%) protein kinase activator activity (12.2%)" "IPR003594 (12.8%) IPR005467 (12.8%) IPR033405 (12.8%)" "Histidine kinase/HSP90-like ATPase domain (12.8%) Histidine kinase domain (12.8%) Domain of unknown function DUF5112 (12.8%)" GNHVLNVSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR037066 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent receptor, plug domain superfamily (13%)" VAVDLVSLKPQDTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR010720 (16.9%) IPR051563 (16.9%) IPR055133 (16.9%)" "Alpha-L-arabinofuranosidase, C-terminal (16.9%) Glycosyl Hydrolase Family 51 (16.9%) Arabinosidase BT_3657-like, N-terminal (16.9%)" VLLANGNTPNLLLNLK Pseudomonadati Bacteria Pseudomonadati 2.7.2.11 (100%) glutamate 5-kinase (100%) GO:0055129 (24.2%) GO:0005829 (24.2%) "GO:0004349 (24.2%) GO:0005524 (24.2%) GO:0004350 (1.6%)" L-proline biosynthetic process (24.2%) cytosol (24.2%) "glutamate 5-kinase activity (24.2%) ATP binding (24.2%) glutamate-5-semialdehyde dehydrogenase activity (1.6%)" "IPR001048 (18.6%) IPR005715 (17.4%) IPR041739 (17.4%)" "Aspartate/glutamate/uridylate kinase (18.6%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (17.4%) Glutamate-5-kinase domain (17.4%)" AKVQELTEVLPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" YLASVNLSR root GO:0006886 (4.5%) "GO:0009279 (90.9%) GO:0005768 (4.5%)" intracellular protein transport (4.5%) "cell outer membrane (90.9%) endosome (4.5%)" "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" YSNENENWGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.4%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.4%)" DLVNYFEEGDTFLFNNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.99.17 (100%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (100%) GO:0002099 (35.1%) GO:0005737 (29.7%) GO:0051075 (35.1%) tRNA wobble guanine modification (35.1%) cytoplasm (29.7%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (35.1%) "IPR003699 (27.1%) IPR036100 (25%) IPR042118 (25%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA (27.1%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily (25%) QueA, domain 1 (25%)" VVSSVEECLEYGGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YDGMDPELGYGVNSWASGVDLGYYPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (31.6%) GO:0009279 (36.8%) GO:0015344 (31.6%) siderophore transmembrane transport (31.6%) cell outer membrane (36.8%) siderophore uptake transmembrane transporter activity (31.6%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" VLLEETMSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.5%) GO:0005829 (16.5%) "GO:0003677 (16.5%) GO:0005524 (16.5%) GO:0043138 (16.5%)" recombinational repair (16.5%) cytosol (16.5%) "DNA binding (16.5%) ATP binding (16.5%) 3'-5' DNA helicase activity (16.5%)" "IPR000212 (20.2%) IPR014016 (20.2%) IPR014017 (20.2%)" "DNA helicase, UvrD/REP type (20.2%) UvrD-like helicase, ATP-binding domain (20.2%) UvrD-like DNA helicase, C-terminal (20.2%)" LDLDAEGLK root "2.7.13.3 (40%) 1.3.8.4 (20%) 2.7.1.69 (20%)" "histidine kinase (40%) isovaleryl-CoA dehydrogenase (20%) Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.1952.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.2012.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 an2.7.1.208 (20%)" "GO:0009401 (27.3%) GO:0007234 (1.3%) GO:0015074 (1.3%)" GO:0005886 (27.9%) "GO:0015577 (27.3%) GO:0016491 (2.6%) GO:0000155 (1.3%)" "phosphoenolpyruvate-dependent sugar phosphotransferase system (27.3%) osmosensory signaling via phosphorelay pathway (1.3%) DNA integration (1.3%)" plasma membrane (27.9%) "galactitol transmembrane transporter activity (27.3%) oxidoreductase activity (2.6%) phosphorelay sensor kinase activity (1.3%)" "IPR004703 (22.7%) IPR013014 (22.7%) IPR013853 (22.7%)" "Phosphotransferase system, sugar-specific permease component (22.7%) Phosphotransferase system, EIIC component, type 2 (22.7%) Galactitol permease IIC component (22.7%)" GECDFLDPMCGSGTLALEAALLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.8%) IPR002052 (16.8%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) DNA methylase, N-6 adenine-specific, conserved site (16.8%) THUMP domain (16.8%)" GLVVEGVLDNGDGTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LNTESPAWAVDR Bacteroidota Bacteria Pseudomonadati Bacteroidota IPR025350 (100%) Protein of unknown function DUF4254 (100%) DLCYHLQFLPANSQDFGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.2%) IPR008969 (48.8%)" "Family of unknown function DUF5686 (51.2%) Carboxypeptidase-like, regulatory domain superfamily (48.8%)" NLGLSTSADKHYDFSCLLTSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR035986 (100%) PKD domain superfamily (100%) NQPLDHDSLDHLLQTFFQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) QYYYGLSVGAAYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (84.6%) IPR011250 (15.4%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (84.6%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (15.4%)" EGMSMQYAGGLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0008270 (47.6%) GO:0016603 (47.6%) GO:0016740 (2.4%)" "zinc ion binding (47.6%) glutaminyl-peptide cyclotransferase activity (47.6%) transferase activity (2.4%)" "IPR007484 (51.2%) IPR040234 (48.8%)" "Peptidase M28 (51.2%) Glutaminyl-peptide cyclotransferase-like (48.8%)" YKQVYNLYSVVVTPDESQVYTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GNKVDDYELTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (22%) IPR057601 (22%) IPR008969 (19.5%)" "TonB-dependent receptor-like (22%) TonB-dependent transporter Oar-like, beta-barrel domain (22%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" WDATGNWDVLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" YHVMNLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.6%) IPR039426 (20.6%) IPR012910 (20.1%)" "TonB-dependent receptor-like, beta-barrel (20.6%) TonB-dependent receptor-like (20.6%) TonB-dependent receptor, plug domain (20.1%)" GNLWMLSVNQLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (25%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR009057 (12.2%) IPR011110 (12.2%) IPR011123 (12.2%)" "Homedomain-like superfamily (12.2%) Two component regulator propeller (12.2%) Two component regulator three Y (12.2%)" LLLHLAAHAEHFTTHPLGAALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) "GO:0005886 (16.4%) GO:0016020 (0.4%)" "GO:0005524 (16.8%) GO:0015086 (16.8%) GO:0016887 (16.8%)" "plasma membrane (16.4%) membrane (0.4%)" "ATP binding (16.8%) cadmium ion transmembrane transporter activity (16.8%) ATP hydrolysis activity (16.8%)" "IPR001757 (10.5%) IPR051014 (10.5%) IPR018303 (10.2%)" "P-type ATPase (10.5%) Cation Transport ATPase Type IB (10.5%) P-type ATPase, phosphorylation site (10.2%)" ESAEGLVSMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" LALPEYWTLPFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026950 (50.8%) IPR038636 (49.2%)" "Capsule assembly protein Wzi (50.8%) Capsule assembly protein Wzi superfamily (49.2%)" EDMGYTGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (38.5%) "GO:0004556 (30.8%) GO:0043169 (30.8%)" carbohydrate metabolic process (38.5%) "alpha-amylase activity (30.8%) cation binding (30.8%)" "IPR006047 (38.5%) IPR006046 (30.8%) IPR017853 (30.8%)" "Glycosyl hydrolase family 13, catalytic domain (38.5%) Alpha amylase (30.8%) Glycoside hydrolase superfamily (30.8%)" FVDDLTTR root "GO:0035418 (3.7%) GO:1904071 (3.7%) GO:0006869 (2.3%)" "GO:0016020 (3.7%) GO:0030424 (3.7%) GO:0048788 (3.7%)" "GO:0008270 (6.4%) GO:0005524 (5.3%) GO:0016887 (5.1%)" "protein localization to synapse (3.7%) presynaptic active zone assembly (3.7%) lipid transport (2.3%)" "membrane (3.7%) axon (3.7%) cytoskeleton of presynaptic active zone (3.7%)" "zinc ion binding (6.4%) ATP binding (5.3%) ATP hydrolysis activity (5.1%)" "IPR052098 (7%) IPR001478 (6.8%) IPR036034 (6.8%)" "Presynaptic Scaffold Protein Bassoon/Piccolo (7%) PDZ domain (6.8%) PDZ superfamily (6.8%)" FGLVYNDAEGNFLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20%) IPR012910 (20%) IPR036942 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" FYTLSPMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) TYVMLDR root "5.6.2.4 (75%) 1.14.13.- (12.5%) 2.4.2.- (12.5%)" "DNA 3'-5' helicase (75%) With NADH or NADPH as one donor, and incorporation of one atom of oxygen (12.5%) Pentosyltransferases (12.5%)" "GO:0000725 (8.2%) GO:0006281 (1.4%) GO:0007165 (1.4%)" "GO:0005634 (8.2%) GO:0005829 (5.5%) GO:0005886 (2.7%)" "GO:0003677 (9.6%) GO:0005524 (9.6%) GO:0016787 (9.6%)" "recombinational repair (8.2%) DNA repair (1.4%) signal transduction (1.4%)" "nucleus (8.2%) cytosol (5.5%) plasma membrane (2.7%)" "DNA binding (9.6%) ATP binding (9.6%) hydrolase activity (9.6%)" "IPR024361 (9.5%) IPR012337 (7.6%) IPR012640 (7.6%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (9.5%) Ribonuclease H-like superfamily (7.6%) Membrane lipoprotein, lipid attachment site (7.6%)" DVLEAFCR root "2.8.1.13 (50%) 2.7.7.19 (25%) 3.1.21.10 (25%)" "tRNA-uridine 2-sulfurtransferase (50%) polynucleotide adenylyltransferase (25%) crossover junction endodeoxyribonuclease (25%)" "GO:0002143 (1.9%) GO:0006281 (1%) GO:0006310 (1%)" "GO:0005737 (2.9%) GO:0043190 (1.9%) GO:0005615 (1%)" "GO:0005524 (32.7%) GO:0016887 (29.8%) GO:0000049 (1.9%)" "tRNA wobble position uridine thiolation (1.9%) DNA repair (1%) DNA recombination (1%)" "cytoplasm (2.9%) ATP-binding cassette (ABC) transporter complex (1.9%) extracellular space (1%)" "ATP binding (32.7%) ATP hydrolysis activity (29.8%) tRNA binding (1.9%)" "IPR003439 (15.7%) IPR003593 (15.7%) IPR017871 (15.7%)" "ABC transporter-like, ATP-binding domain (15.7%) AAA+ ATPase domain (15.7%) ABC transporter-like, conserved site (15.7%)" FDLPEDYDPCSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (11.1%) GO:0008360 (11.1%) GO:0009252 (11.1%)" "GO:0005886 (11.1%) GO:0030288 (11.1%)" "GO:0004180 (11.1%) GO:0008658 (11.1%) GO:0008955 (11.1%)" "proteolysis (11.1%) regulation of cell shape (11.1%) peptidoglycan biosynthetic process (11.1%)" "plasma membrane (11.1%) outer membrane-bounded periplasmic space (11.1%)" "carboxypeptidase activity (11.1%) penicillin binding (11.1%) peptidoglycan glycosyltransferase activity (11.1%)" "IPR001264 (16.7%) IPR001460 (16.7%) IPR012338 (16.7%)" "Glycosyl transferase, family 51 (16.7%) Penicillin-binding protein, transpeptidase (16.7%) Beta-lactamase/transpeptidase-like (16.7%)" AMTQEFLDEWLGYFLNPGNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.4.1.1 (100%) pyruvate carboxylase (100%) GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (22%) IPR003379 (22%) IPR055268 (22%)" "Pyruvate carboxyltransferase (22%) Carboxylase, conserved domain (22%) Pyruvate carboxylase-like (22%)" TLYCELDLVEGETEKAELLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006865 (3.4%) GO:0051301 (3.4%)" GO:0005886 (22.4%) "GO:0005524 (25.9%) GO:0016887 (24.1%) GO:0022857 (20.7%)" "amino acid transport (3.4%) cell division (3.4%)" plasma membrane (22.4%) "ATP binding (25.9%) ATP hydrolysis activity (24.1%) transmembrane transporter activity (20.7%)" "IPR003439 (20.6%) IPR027417 (20.6%) IPR003593 (19.1%)" "ABC transporter-like, ATP-binding domain (20.6%) P-loop containing nucleoside triphosphate hydrolase (20.6%) AAA+ ATPase domain (19.1%)" MGAEALYQLLQNVDLDSLSYELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (17%) GO:0000428 (17%) "GO:0003677 (17%) GO:0003899 (17%) GO:0000287 (16%)" DNA-templated transcription (17%) DNA-directed RNA polymerase complex (17%) "DNA binding (17%) DNA-directed RNA polymerase activity (17%) magnesium ion binding (16%)" "IPR006592 (9.6%) IPR007080 (9.6%) IPR045867 (9.6%)" "RNA polymerase, N-terminal (9.6%) RNA polymerase Rpb1, domain 1 (9.6%) DNA-directed RNA polymerase, subunit beta-prime (9.6%)" YASFGDALGNALTMDPTQPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" LHAMSAYGLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) GDGTYEVSASLADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QVNPGDRLPSER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003677 (50%) GO:0003700 (50%)" "DNA binding (50%) DNA-binding transcription factor activity (50%)" "IPR000524 (20%) IPR008920 (20%) IPR011711 (20%)" "Transcription regulator HTH, GntR (20%) Transcription regulator FadR/GntR, C-terminal (20%) GntR, C-terminal (20%)" SYFGTEVSTLGGLGLETLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (14%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (14%)" "IPR002489 (12.8%) IPR002932 (12.8%) IPR006982 (12.8%)" "Glutamate synthase, alpha subunit, C-terminal (12.8%) Glutamate synthase domain (12.8%) Glutamate synthase, central-N (12.8%)" DQYGEQTYAQYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" ELSLQLPVK root 2.7.1.150 (100%) 1-phosphatidylinositol-3-phosphate 5-kinase (100%) GO:0046854 (25%) GO:0010008 (25%) "GO:0000285 (25%) GO:0005524 (25%)" phosphatidylinositol phosphate biosynthetic process (25%) endosome membrane (25%) "1-phosphatidylinositol-3-phosphate 5-kinase activity (25%) ATP binding (25%)" "IPR002498 (25%) IPR027409 (25%) IPR027483 (25%)" "Phosphatidylinositol-4-phosphate 4/5-kinase, core (25%) GroEL-like apical domain superfamily (25%) Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily (25%)" FFTNLTHELR Bacteria Bacteria 2.7.13.3 (100%) histidine kinase (100%) "GO:0016020 (17.8%) GO:0005886 (1%)" "GO:0000155 (25.5%) GO:0003700 (24.6%) GO:0043565 (24.6%)" "membrane (17.8%) plasma membrane (1%)" "phosphorelay sensor kinase activity (25.5%) DNA-binding transcription factor activity (24.6%) sequence-specific DNA binding (24.6%)" "IPR003661 (7.3%) IPR003594 (7.2%) IPR005467 (7.2%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.3%) Histidine kinase/HSP90-like ATPase domain (7.2%) Histidine kinase domain (7.2%)" LLVSQPKPASEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.75 (100%) uroporphyrinogen-III synthase (100%) "GO:0006780 (30.4%) GO:0033014 (3.6%) GO:0032259 (0.9%)" GO:0005829 (30.4%) "GO:0004852 (33.9%) GO:0008168 (0.9%)" "uroporphyrinogen III biosynthetic process (30.4%) tetrapyrrole biosynthetic process (3.6%) methylation (0.9%)" cytosol (30.4%) "uroporphyrinogen-III synthase activity (33.9%) methyltransferase activity (0.9%)" "IPR003754 (34.9%) IPR036108 (33.9%) IPR039793 (31.2%)" "Tetrapyrrole biosynthesis, uroporphyrinogen III synthase (34.9%) Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily (33.9%) Uroporphyrinogen-III synthase (31.2%)" KTVQQFVFNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025590 (100%) Protein of unknown function DUF4348 (100%) VEWPFGYGLSYTTFAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48%) GO:0005975 (2%)" GO:0008422 (50%) "glucan catabolic process (48%) carbohydrate metabolic process (2%)" beta-glucosidase activity (50%) "IPR002772 (13.4%) IPR050288 (13.4%) IPR001764 (12.8%)" "Glycoside hydrolase family 3 C-terminal domain (13.4%) Cellulose-degrading glycosyl hydrolase 3 (13.4%) Glycoside hydrolase, family 3, N-terminal (12.8%)" TMMEHVFGPNGTFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VNLGAGSAEQGSQSGLEDLTRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" DELLLPFVDLK Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.1%) GO:0006102 (20.1%)" "GO:0004450 (20.1%) GO:0000287 (19.6%) GO:0051287 (19.6%)" "tricarboxylic acid cycle (20.1%) isocitrate metabolic process (20.1%)" "isocitrate dehydrogenase (NADP+) activity (20.1%) magnesium ion binding (19.6%) NAD binding (19.6%)" "IPR004790 (33.6%) IPR024084 (33.6%) IPR019818 (32.7%)" "Isocitrate dehydrogenase NADP-dependent (33.6%) Isopropylmalate dehydrogenase-like domain (33.6%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.7%)" LGTVPDTDGSNSTTGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012640 (50%) IPR024361 (50%)" "Membrane lipoprotein, lipid attachment site (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" LGPLQNSELEFKPFLVYTGESGLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027417 (33.3%) IPR041685 (33.3%) IPR051396 (33.3%)" "P-loop containing nucleoside triphosphate hydrolase (33.3%) Endonuclease GajA/Old nuclease/RecF-like, AAA domain (33.3%) Bacterial Antiviral Defense Nuclease (33.3%)" GNTLGGSYSYSSDTSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (46.2%) GO:0005737 (46.2%)" GO:0016787 (7.7%) "extracellular region (46.2%) cytoplasm (46.2%)" hydrolase activity (7.7%) "IPR028994 (17.8%) IPR003284 (13.3%) IPR006530 (13.3%)" "Integrin alpha, N-terminal (17.8%) Salmonella virulence plasmid 65kDa B protein (13.3%) YD repeat (13.3%)" AEELGMHELNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (25.3%) "GO:0005840 (25.3%) GO:0005737 (24%)" "GO:0008276 (24%) GO:0008168 (1.3%)" methylation (25.3%) "ribosome (25.3%) cytoplasm (24%)" "protein methyltransferase activity (24%) methyltransferase activity (1.3%)" "IPR004498 (33.3%) IPR029063 (33.3%) IPR050078 (33.3%)" "Ribosomal protein L11 methyltransferase (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%) Ribosomal protein L11 methyltransferase PrmA (33.3%)" SSLLYLK root "3.1.4.52 (53.4%) 2.7.7.65 (38.2%) 2.1.1.182 (2%)" "cyclic-guanylate-specific phosphodiesterase (53.4%) diguanylate cyclase (38.2%) 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (2%)" "GO:0071732 (13.2%) GO:0030244 (7.8%) GO:0007165 (0.7%)" "GO:0016020 (17.1%) GO:0005886 (2.3%) GO:0005634 (1.7%)" "GO:0071111 (14%) GO:0052621 (9.3%) GO:0016301 (1.3%)" "cellular response to nitric oxide (13.2%) cellulose biosynthetic process (7.8%) signal transduction (0.7%)" "membrane (17.1%) plasma membrane (2.3%) nucleus (1.7%)" "cyclic-guanylate-specific phosphodiesterase activity (14%) diguanylate cyclase activity (9.3%) kinase activity (1.3%)" "IPR001633 (10%) IPR035919 (9.9%) IPR000160 (9.5%)" "EAL domain (10%) EAL domain superfamily (9.9%) GGDEF domain (9.5%)" LVQLFQAPTLQMVTFTLTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013131 (18.1%) IPR050988 (18.1%) IPR013118 (16.7%)" "Mannitol dehydrogenase, N-terminal (18.1%) Mannitol Dehydrogenase/Oxidoreductase (18.1%) Mannitol dehydrogenase, C-terminal (16.7%)" HDKLVGELSNTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.2%) IPR003593 (20.2%) IPR032781 (20.2%)" "ABC transporter-like, ATP-binding domain (20.2%) AAA+ ATPase domain (20.2%) ABC-transporter extension domain (20.2%)" ETGSVLDHEYCVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.7%) GO:0005737 (19%) "GO:0004177 (20.7%) GO:0008270 (20.7%) GO:0008237 (19%)" proteolysis (20.7%) cytoplasm (19%) "aminopeptidase activity (20.7%) zinc ion binding (20.7%) metallopeptidase activity (19%)" "IPR001948 (52.1%) IPR023358 (47.9%)" "Peptidase M18 (52.1%) Peptidase M18, domain 2 (47.9%)" YTLEYPNR root GO:0030490 (4.5%) "GO:0005737 (4.5%) GO:0016020 (4.5%)" GO:0005524 (86.4%) maturation of SSU-rRNA (4.5%) "cytoplasm (4.5%) membrane (4.5%)" ATP binding (86.4%) "IPR012547 (38.8%) IPR018631 (35.3%) IPR027417 (22.4%)" "PD-(D/E)XK nuclease superfamily 9 (38.8%) AAA-ATPase-like domain (35.3%) P-loop containing nucleoside triphosphate hydrolase (22.4%)" LHNTRGEELTPDSNGPESVYFFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.7%) IPR000795 (7.7%) IPR005225 (7.7%)" "Elongation factor EFG, domain V-like (7.7%) Translational (tr)-type GTP-binding domain (7.7%) Small GTP-binding domain (7.7%)" ALENQEEVNLDFALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (13.8%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (13.8%)" "IPR002489 (12.6%) IPR002932 (12.6%) IPR006982 (12.6%)" "Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase domain (12.6%) Glutamate synthase, central-N (12.6%)" GEWKEDEPLLVR Bacteria Bacteria "3.5.4.25 (51.6%) 4.1.99.12 (48.4%)" "GTP cyclohydrolase II (51.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (48.4%)" GO:0009231 (12.7%) GO:0005829 (12.7%) "GO:0003935 (12.7%) GO:0005525 (12.7%) GO:0008686 (12.7%)" riboflavin biosynthetic process (12.7%) cytosol (12.7%) "GTP cyclohydrolase II activity (12.7%) GTP binding (12.7%) 3,4-dihydroxy-2-butanone-4-phosphate synthase activity (12.7%)" "IPR000422 (16.8%) IPR000926 (16.8%) IPR017945 (16.8%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.8%) GTP cyclohydrolase II, RibA (16.8%) DHBP synthase RibB-like alpha/beta domain superfamily (16.8%)" MSVEGLSEMAGFNTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR009057 (50%) IPR018060 (50%)" "Homedomain-like superfamily (50%) AraC-like, DNA binding HTH domain (50%)" ELLEAGEWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030170 (100%) pyridoxal phosphate binding (100%) "IPR001608 (33.7%) IPR011078 (33.7%) IPR029066 (32.6%)" "Alanine racemase, N-terminal (33.7%) Pyridoxal phosphate homeostasis protein (33.7%) PLP-binding barrel (32.6%)" TVNFDNVHLVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) VVGTTNGAVTDLDGNFTLTNVPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FLALVLK root "2.1.1.85 (19.3%) 7.1.1.9 (14.1%) 3.2.1.1 (9.6%)" "protein-histidine N-methyltransferase (19.3%) cytochrome-c oxidase (14.1%) alpha-amylase (9.6%)" "GO:0032259 (1.1%) GO:0006355 (1%) GO:0006119 (0.8%)" "GO:0005886 (8.8%) GO:0016020 (7.5%) GO:0005634 (2.8%)" "GO:0005524 (5.5%) GO:0016887 (3.1%) GO:0140359 (2.4%)" "methylation (1.1%) regulation of DNA-templated transcription (1%) oxidative phosphorylation (0.8%)" "plasma membrane (8.8%) membrane (7.5%) nucleus (2.8%)" "ATP binding (5.5%) ATP hydrolysis activity (3.1%) ABC-type transporter activity (2.4%)" "IPR027417 (4.1%) IPR003593 (3.6%) IPR003439 (2.8%)" "P-loop containing nucleoside triphosphate hydrolase (4.1%) AAA+ ATPase domain (3.6%) ABC transporter-like, ATP-binding domain (2.8%)" NLVLTLDK root "3.4.16.4 (44.8%) 1.5.1.3 (31%) 2.4.1.129 (6.9%)" "serine-type D-Ala-D-Ala carboxypeptidase (44.8%) dihydrofolate reductase (31%) Transferred entry: 2.4.99.28 (6.9%)" "GO:0071555 (11.5%) GO:0008360 (9.2%) GO:0009252 (9.2%)" "GO:0005886 (11.9%) GO:0005829 (2.1%) GO:0016020 (1.3%)" "GO:0008658 (11.5%) GO:0071972 (9.4%) GO:0009002 (8.7%)" "cell wall organization (11.5%) regulation of cell shape (9.2%) peptidoglycan biosynthetic process (9.2%)" "plasma membrane (11.9%) cytosol (2.1%) membrane (1.3%)" "penicillin binding (11.5%) peptidoglycan L,D-transpeptidase activity (9.4%) serine-type D-Ala-D-Ala carboxypeptidase activity (8.7%)" "IPR001460 (12%) IPR005311 (12%) IPR012338 (12%)" "Penicillin-binding protein, transpeptidase (12%) Penicillin-binding protein, dimerisation domain (12%) Beta-lactamase/transpeptidase-like (12%)" TVDKVNPGEQQPETDHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (69.2%) GO:0016787 (30.8%) carbohydrate metabolic process (69.2%) hydrolase activity (30.8%) "IPR008928 (20%) IPR012878 (20%) IPR032275 (20%)" "Six-hairpin glycosidase superfamily (20%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (20%) Domain of unknown function DUF4986 (20%)" AQGLDDLTVYPLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0042777 (19.8%) "GO:0005886 (19.8%) GO:0045259 (19.8%)" "GO:0005524 (19.8%) GO:0046933 (19.8%) GO:0016787 (0.8%)" proton motive force-driven plasma membrane ATP synthesis (19.8%) "plasma membrane (19.8%) proton-transporting ATP synthase complex (19.8%)" "ATP binding (19.8%) proton-transporting ATP synthase activity, rotational mechanism (19.8%) hydrolase activity (0.8%)" "IPR000131 (51%) IPR035968 (49%)" "ATP synthase, F1 complex, gamma subunit (51%) ATP synthase, F1 complex, gamma subunit superfamily (49%)" VDMANEDVVYLTAEDEESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007645 (8.3%) IPR015712 (8.3%) IPR019462 (8.3%)" "RNA polymerase Rpb2, domain 3 (8.3%) DNA-directed RNA polymerase, subunit 2 (8.3%) DNA-directed RNA polymerase, beta subunit, external 1 domain (8.3%)" KGMELDLPELPELMLDNTDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" FGSFVVLPGLNPGMLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (23.7%) GO:0043952 (23.7%) GO:0065002 (23.7%)" "GO:0005886 (23.7%) GO:0016020 (2.6%)" "protein targeting (23.7%) protein transport by the Sec complex (23.7%) intracellular protein transmembrane transport (23.7%)" "plasma membrane (23.7%) membrane (2.6%)" "IPR002208 (25.6%) IPR023201 (25.6%) IPR030659 (25.6%)" "SecY/SEC61-alpha family (25.6%) SecY domain superfamily (25.6%) SecY conserved site (25.6%)" LGTFYNNPSFGYGGYCLPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (28.3%) GO:0006065 (10.7%) GO:0006072 (1.9%)" "GO:0051287 (29.6%) GO:0003979 (28.3%) GO:0016616 (1.3%)" "polysaccharide biosynthetic process (28.3%) UDP-glucuronate biosynthetic process (10.7%) glycerol-3-phosphate metabolic process (1.9%)" "NAD binding (29.6%) UDP-glucose 6-dehydrogenase activity (28.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (1.3%)" "IPR001732 (11.4%) IPR014026 (11.4%) IPR017476 (11.4%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.4%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.4%) UDP-glucose/GDP-mannose dehydrogenase (11.4%)" EYDKEDVPTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005840 (53.3%) GO:1990904 (46.7%)" "ribosome (53.3%) ribonucleoprotein complex (46.7%)" "IPR001790 (34.8%) IPR047865 (34.8%) IPR043141 (30.4%)" "Large ribosomal subunit protein uL10 (34.8%) Large ribosomal subunit protein uL10, bacteria/organella (34.8%) Large ribosomal subunit protein uL10-like domain superfamily (30.4%)" KPHYLNSYDSVTLLEEALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" VALNDAVFGLEPNDHVLYLDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" ACNVSGAALHQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0043200 (20.7%) GO:0006355 (5.4%)" GO:0005829 (20.7%) "GO:0043565 (53%) GO:0003700 (0.3%)" "response to amino acid (20.7%) regulation of DNA-templated transcription (5.4%)" cytosol (20.7%) "sequence-specific DNA binding (53%) DNA-binding transcription factor activity (0.3%)" "IPR000485 (15.1%) IPR036388 (15%) IPR036390 (15%)" "AsnC-type HTH domain (15.1%) Winged helix-like DNA-binding domain superfamily (15%) Winged helix DNA-binding domain superfamily (15%)" LHYFAEWWK Bacteria Bacteria 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.3%) GO:0006096 (14.3%) GO:0051156 (14.3%)" GO:0005829 (14.3%) "GO:0004347 (14.3%) GO:0048029 (14.3%) GO:0097367 (14.1%)" "gluconeogenesis (14.3%) glycolytic process (14.3%) glucose 6-phosphate metabolic process (14.3%)" cytosol (14.3%) "glucose-6-phosphate isomerase activity (14.3%) monosaccharide binding (14.3%) carbohydrate derivative binding (14.1%)" "IPR001672 (20%) IPR035482 (20%) IPR018189 (19.8%)" "Phosphoglucose isomerase (PGI) (20%) Phosphoglucose isomerase, SIS domain 2 (20%) Phosphoglucose isomerase, conserved site (19.8%)" VVTGDTAATALELGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.10 (100%) P-type Ca(2+) transporter (100%) "GO:0005886 (20%) GO:0012505 (20%)" "GO:0005388 (20%) GO:0005524 (20%) GO:0016887 (20%)" "plasma membrane (20%) endomembrane system (20%)" "P-type calcium transporter activity (20%) ATP binding (20%) ATP hydrolysis activity (20%)" "IPR001757 (9.4%) IPR004014 (9.4%) IPR006068 (9.4%)" "P-type ATPase (9.4%) Cation-transporting P-type ATPase, N-terminal (9.4%) Cation-transporting P-type ATPase, C-terminal (9.4%)" YAWTNFAESFTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.14.- (100%) Dipeptidyl-peptidases and tripeptidyl-peptidases (100%) "GO:0006508 (25%) GO:0043171 (25%)" "GO:0008239 (25%) GO:0070009 (25%)" "proteolysis (25%) peptide catabolic process (25%)" "dipeptidyl-peptidase activity (25%) serine-type aminopeptidase activity (25%)" "IPR019500 (35.1%) IPR009003 (32.5%) IPR043504 (32.5%)" "Peptidase S46 (35.1%) Peptidase S1, PA clan (32.5%) Peptidase S1, PA clan, chymotrypsin-like fold (32.5%)" SFEEMLQK root "6.3.5.5 (46.3%) 6.3.4.16 (41.1%) 1.17.1.4 (9.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (46.3%) carbamoyl-phosphate synthase (ammonia) (41.1%) xanthine dehydrogenase (9.5%)" "GO:0006541 (11.4%) GO:0006221 (11.2%) GO:0006526 (11.2%)" "GO:0005737 (11.4%) GO:0010008 (0.2%)" "GO:0005524 (11.6%) GO:0004088 (11.4%) GO:0046872 (11.4%)" "glutamine metabolic process (11.4%) pyrimidine nucleotide biosynthetic process (11.2%) L-arginine biosynthetic process (11.2%)" "cytoplasm (11.4%) endosome membrane (0.2%)" "ATP binding (11.6%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (11.4%) metal ion binding (11.4%)" "IPR005479 (7.7%) IPR005480 (7.7%) IPR006275 (7.7%)" "Carbamoyl phosphate synthase, ATP-binding domain (7.7%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (7.7%) Carbamoyl-phosphate synthase, large subunit (7.7%)" TDKGVDFESMASELDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR000943 (10%) IPR007624 (10%) IPR007627 (10%)" "RNA polymerase sigma-70 (10%) RNA polymerase sigma-70 region 3 (10%) RNA polymerase sigma-70 region 2 (10%)" DGVTTDEDGYFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (17.8%) IPR012910 (17.8%) IPR039426 (17.8%)" "TonB-dependent receptor-like, beta-barrel (17.8%) TonB-dependent receptor, plug domain (17.8%) TonB-dependent receptor-like (17.8%)" KGDNVLFTAFGAGFVHGASFYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20.8%) GO:0044550 (20.8%)" GO:0005737 (18.9%) "GO:0004315 (20.8%) GO:0033818 (18.9%)" "fatty acid biosynthetic process (20.8%) secondary metabolite biosynthetic process (20.8%)" cytoplasm (18.9%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20.8%) beta-ketoacyl-acyl-carrier-protein synthase III activity (18.9%)" "IPR013747 (25.6%) IPR013751 (25.6%) IPR016039 (25.6%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25.6%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25.6%) Thiolase-like (25.6%)" VDKESLLR root "6.3.1.1 (75.4%) 2.7.7.49 (13%) 2.7.1.- (2.9%)" "aspartate--ammonia ligase (75.4%) RNA-directed DNA polymerase (13%) Phosphotransferases with an alcohol group as acceptor (2.9%)" "GO:0070981 (17.1%) GO:0006096 (1.1%) GO:0071281 (1.1%)" "GO:0005829 (19.3%) GO:0005739 (1.4%) GO:0005634 (0.7%)" "GO:0005524 (18.6%) GO:0004071 (17.9%) GO:0003964 (3.2%)" "L-asparagine biosynthetic process (17.1%) glycolytic process (1.1%) cellular response to iron ion (1.1%)" "cytosol (19.3%) mitochondrion (1.4%) nucleus (0.7%)" "ATP binding (18.6%) aspartate-ammonia ligase activity (17.9%) RNA-directed DNA polymerase activity (3.2%)" "IPR004618 (18.2%) IPR006195 (18.2%) IPR045864 (17.5%)" "Aspartate--ammonia ligase (18.2%) Aminoacyl-tRNA synthetase, class II (18.2%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (17.5%)" VNTMHFHLTEDQGWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.4%) IPR015883 (17.4%) IPR025705 (17.4%)" "PA14 domain (17.4%) Glycoside hydrolase family 20, catalytic domain (17.4%) Beta-hexosaminidase (17.4%)" LNGNGWAYLANTNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LLEGAANFDDEVMELYLDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (20%) GO:0005737 (20%) "GO:0003746 (20%) GO:0003924 (20%) GO:0005525 (20%)" ribosome disassembly (20%) cytoplasm (20%) "translation elongation factor activity (20%) GTPase activity (20%) GTP binding (20%)" "IPR000640 (6.4%) IPR000795 (6.4%) IPR004161 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translational (tr)-type GTP-binding domain (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%)" SQDELFQTCDLVSLHLPATPETLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.9%) GO:0033711 (2.1%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.9%) 4-phosphoerythronate dehydrogenase activity (2.1%)" "IPR006139 (31.2%) IPR006140 (31.2%) IPR036291 (31.2%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (31.2%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (31.2%) NAD(P)-binding domain superfamily (31.2%)" ELGDYEGLTVTVGSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.4%) "GO:0003677 (25.4%) GO:0003917 (25.4%) GO:0046872 (23.9%)" DNA topological change (25.4%) "DNA binding (25.4%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.4%) metal ion binding (23.9%)" "IPR000380 (7.7%) IPR013497 (7.7%) IPR025589 (7.7%)" "DNA topoisomerase, type IA (7.7%) DNA topoisomerase, type IA, central (7.7%) Topoisomerase C-terminal repeat (7.7%)" VLGLLNLK root "1.1.-.- (33.3%) 2.7.11.1 (33.3%) 2.7.7.6 (33.3%)" "Acting on the CH-OH group of donors (33.3%) non-specific serine/threonine protein kinase (33.3%) DNA-directed RNA polymerase (33.3%)" "GO:0045493 (6.2%) GO:0006869 (0.9%) GO:0061817 (0.9%)" "GO:0005886 (21.1%) GO:0016020 (11.5%) GO:0031410 (2.2%)" "GO:0050660 (14.9%) GO:0016798 (6.2%) GO:0004930 (2.2%)" "xylan catabolic process (6.2%) lipid transport (0.9%) endoplasmic reticulum-plasma membrane tethering (0.9%)" "plasma membrane (21.1%) membrane (11.5%) cytoplasmic vesicle (2.2%)" "flavin adenine dinucleotide binding (14.9%) hydrolase activity, acting on glycosyl bonds (6.2%) G protein-coupled receptor activity (2.2%)" "IPR000644 (7.3%) IPR046342 (7.3%) IPR044751 (7.1%)" "CBS domain (7.3%) CBS domain superfamily (7.3%) Ion transporter-like, CBS domain (7.1%)" WDLTESWDPTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) LGEELQVVNLQNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (12.9%) GO:0006047 (12.9%) GO:0006487 (12.9%)" GO:0005829 (12.9%) "GO:0004360 (12.9%) GO:0097367 (11.8%)" "fructose 6-phosphate metabolic process (12.9%) UDP-N-acetylglucosamine metabolic process (12.9%) protein N-linked glycosylation (12.9%)" cytosol (12.9%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.9%) carbohydrate derivative binding (11.8%)" "IPR017932 (13.6%) IPR001347 (12.5%) IPR005855 (12.5%)" "Glutamine amidotransferase type 2 domain (13.6%) SIS domain (12.5%) Glucosamine-fructose-6-phosphate aminotransferase, isomerising (12.5%)" GNPGLKPSFTQNFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR041700 (83.6%) IPR008969 (14.5%) IPR036942 (1.8%)" "Outer membrane protein beta-barrel domain 3 (83.6%) Carboxypeptidase-like, regulatory domain superfamily (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (1.8%)" GELALTYLYGLGR Pseudomonadati Bacteria Pseudomonadati GO:0006412 (16.8%) "GO:0005829 (16.7%) GO:0015935 (16.7%) GO:0005840 (0.1%)" "GO:0003735 (16.8%) GO:0019843 (16.6%) GO:0000049 (16%)" translation (16.8%) "cytosol (16.7%) small ribosomal subunit (16.7%) ribosome (0.1%)" "structural constituent of ribosome (16.8%) rRNA binding (16.6%) tRNA binding (16%)" "IPR001892 (20.1%) IPR010979 (20%) IPR018269 (19.9%)" "Small ribosomal subunit protein uS13 (20.1%) Small ribosomal subunit protein uS13-like, H2TH (20%) Small ribosomal subunit protein uS13, conserved site (19.9%)" LLSDPEASENDK root 4.2.1.2 (100%) fumarate hydratase (100%) "GO:0006099 (20%) GO:0006091 (0.3%) GO:0006106 (0.2%)" "GO:0005829 (0.1%) GO:0016020 (0.1%)" "GO:0046872 (21.2%) GO:0051539 (21.2%) GO:0004333 (20.7%)" "tricarboxylic acid cycle (20%) generation of precursor metabolites and energy (0.3%) fumarate metabolic process (0.2%)" "cytosol (0.1%) membrane (0.1%)" "metal ion binding (21.2%) 4 iron, 4 sulfur cluster binding (21.2%) fumarate hydratase activity (20.7%)" "IPR004646 (17.8%) IPR051208 (17.8%) IPR004647 (17%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (17.8%) Class-I Fumarase/Tartrate Dehydratase (17.8%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (17%)" LLRPSSLTDQLYLK Bacteroidota Bacteria Pseudomonadati Bacteroidota IPR011630 (100%) Nucleotide modification associated domain 1 (100%) TVLNSNGAELHVNNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (50%) IPR011044 (25%) IPR011047 (25%)" "WD40/YVTN repeat-like-containing domain superfamily (50%) Quinoprotein amine dehydrogenase, beta chain-like (25%) Quinoprotein alcohol dehydrogenase-like superfamily (25%)" SSVLLQSTEEGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (25%) GO:0016020 (25%) "GO:0004222 (25%) GO:0046872 (25%)" proteolysis (25%) membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR004387 (25%) IPR008915 (25%) IPR036034 (25%)" "Peptidase M50, putative membrane-associated zinc metallopeptidase (25%) Peptidase M50 (25%) PDZ superfamily (25%)" LVEQDPHEQGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.3.4 (100%) 3-dehydroquinate synthase (100%) "GO:0008652 (14.8%) GO:0009073 (14.8%) GO:0009423 (14.2%)" GO:0005737 (14.2%) "GO:0003856 (14.8%) GO:0000166 (13.7%) GO:0046872 (13.7%)" "amino acid biosynthetic process (14.8%) aromatic amino acid family biosynthetic process (14.8%) chorismate biosynthetic process (14.2%)" cytoplasm (14.2%) "3-dehydroquinate synthase activity (14.8%) nucleotide binding (13.7%) metal ion binding (13.7%)" "IPR030960 (20.5%) IPR050071 (20.5%) IPR056179 (20.5%)" "3-dehydroquinate synthase, N-terminal domain (20.5%) Dehydroquinate Synthase (20.5%) 3-dehydroquinate synthase, C-terminal domain (20.5%)" YLSGMDPMYTQEQLDNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" YLVVSDCGAVTDFWENHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.3%) IPR002772 (9.3%) IPR011658 (9.3%)" "Glycoside hydrolase, family 3, N-terminal (9.3%) Glycoside hydrolase family 3 C-terminal domain (9.3%) PA14 domain (9.3%)" LLDVANALMGTDLDDDTLLVSTSGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) AALTAECVADVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004560 (50%) carbohydrate metabolic process (50%) alpha-L-fucosidase activity (50%) "IPR008928 (16.7%) IPR012341 (16.7%) IPR016518 (16.7%)" "Six-hairpin glycosidase superfamily (16.7%) Six-hairpin glycosidase-like superfamily (16.7%) Alpha-L-fucosidase (16.7%)" ALADPNSTPQTFGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.4.25 (50.8%) 4.1.99.12 (49.2%)" "GTP cyclohydrolase II (50.8%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (49.2%)" GO:0009231 (12.6%) GO:0005829 (12.6%) "GO:0003935 (12.6%) GO:0005525 (12.6%) GO:0008270 (12.6%)" riboflavin biosynthetic process (12.6%) cytosol (12.6%) "GTP cyclohydrolase II activity (12.6%) GTP binding (12.6%) zinc ion binding (12.6%)" "IPR000422 (16.8%) IPR000926 (16.8%) IPR017945 (16.8%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.8%) GTP cyclohydrolase II, RibA (16.8%) DHBP synthase RibB-like alpha/beta domain superfamily (16.8%)" LSPVVEEYLYSAMEDYR Pseudomonadati Bacteria Pseudomonadati "3.6.4.- (84.8%) 3.6.4.12 (14.9%) 3.6.1.- (0.3%)" "Acting on ATP; involved in cellular and subcellular movement (84.8%) DNA helicase (14.9%) In phosphorus-containing anhydrides (0.3%)" "GO:0006281 (12.6%) GO:0006310 (12.6%)" "GO:0005737 (12.4%) GO:0048476 (11.7%) GO:0016020 (0.1%)" "GO:0005524 (12.6%) GO:0009378 (12.6%) GO:0000400 (11.7%)" "DNA repair (12.6%) DNA recombination (12.6%)" "cytoplasm (12.4%) Holliday junction resolvase complex (11.7%) membrane (0.1%)" "ATP binding (12.6%) four-way junction helicase activity (12.6%) four-way junction DNA binding (11.7%)" "IPR004605 (12.6%) IPR008824 (12.6%) IPR027417 (12.6%)" "Holliday junction branch migration complex subunit RuvB (12.6%) RuvB-like, AAA+ ATPase domain (12.6%) P-loop containing nucleoside triphosphate hydrolase (12.6%)" LEDDNTTLNDVVVLGYGTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (29%) GO:0009279 (71%) iron ion transport (29%) cell outer membrane (71%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTGTNLGLVLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004674 (100%) protein serine/threonine kinase activity (100%) "IPR024361 (23.5%) IPR013783 (22.4%) IPR032675 (21.4%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (23.5%) Immunoglobulin-like fold (22.4%) Leucine-rich repeat domain superfamily (21.4%)" WTPETAGTAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (18.4%) IPR023996 (18.4%) IPR037066 (18.4%)" "TonB-dependent receptor, plug domain (18.4%) TonB-dependent outer membrane protein, SusC/RagA (18.4%) TonB-dependent receptor, plug domain superfamily (18.4%)" ALTSMASSESDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.48 (100%) protein-tyrosine-phosphatase (100%) "GO:0004725 (95%) GO:0004721 (5%)" "protein tyrosine phosphatase activity (95%) phosphoprotein phosphatase activity (5%)" "IPR023485 (25.6%) IPR017867 (24.4%) IPR036196 (24.4%)" "Phosphotyrosine protein phosphatase I (25.6%) Protein-tyrosine phosphatase, low molecular weight (24.4%) Phosphotyrosine protein phosphatase I superfamily (24.4%)" AVAALNGGNDVDFPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" LYQLANELKEYFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EELPACLDHSLFLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.21.10 (100%) crossover junction endodeoxyribonuclease (100%) "GO:0006281 (2%) GO:0006310 (2%)" "GO:0005737 (2%) GO:0043190 (2%) GO:0048476 (2%)" "GO:0005524 (40.8%) GO:0016887 (40.8%) GO:0000287 (2%)" "DNA repair (2%) DNA recombination (2%)" "cytoplasm (2%) ATP-binding cassette (ABC) transporter complex (2%) Holliday junction resolvase complex (2%)" "ATP binding (40.8%) ATP hydrolysis activity (40.8%) magnesium ion binding (2%)" "IPR003439 (19.8%) IPR003593 (19.8%) IPR017871 (19.8%)" "ABC transporter-like, ATP-binding domain (19.8%) AAA+ ATPase domain (19.8%) ABC transporter-like, conserved site (19.8%)" ANSLFSLSYNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LYGSFDVFKEWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" GFQFYDR root "2.7.13.3 (92.9%) 7.2.2.8 (7.1%)" "histidine kinase (92.9%) P-type Cu(+) transporter (7.1%)" "GO:0045664 (4.3%) GO:0045944 (4.3%) GO:0006580 (1.4%)" "GO:0005634 (4.3%) GO:0005886 (2.9%) GO:0016020 (1.4%)" "GO:0000155 (18.8%) GO:0003700 (17.4%) GO:0043565 (17.4%)" "regulation of neuron differentiation (4.3%) positive regulation of transcription by RNA polymerase II (4.3%) ethanolamine metabolic process (1.4%)" "nucleus (4.3%) plasma membrane (2.9%) membrane (1.4%)" "phosphorelay sensor kinase activity (18.8%) DNA-binding transcription factor activity (17.4%) sequence-specific DNA binding (17.4%)" "IPR003661 (5.9%) IPR005467 (5.9%) IPR011110 (5.9%)" "Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (5.9%) Histidine kinase domain (5.9%) Two component regulator propeller (5.9%)" TDFQGYPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" AMDSESFR root "3.4.21.- (97%) 4.2.3.1 (3%)" "Serine endopeptidases (97%) threonine synthase (3%)" "GO:0006508 (30.6%) GO:0000463 (0.9%) GO:0000492 (0.9%)" "GO:0005737 (30.6%) GO:0005634 (0.9%) GO:0070761 (0.9%)" "GO:0008236 (30.6%) GO:0004795 (0.9%) GO:0008270 (0.9%)" "proteolysis (30.6%) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.9%) box C/D snoRNP assembly (0.9%)" "cytoplasm (30.6%) nucleus (0.9%) pre-snoRNP complex (0.9%)" "serine-type peptidase activity (30.6%) threonine synthase activity (0.9%) zinc ion binding (0.9%)" "IPR005151 (13.5%) IPR011659 (13.5%) IPR012393 (13.5%)" "Tail specific protease (13.5%) WD40-like beta-propeller (13.5%) Tricorn protease (13.5%)" SMESGANASLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0017038 (50%) GO:0005886 (50%) protein import (50%) plasma membrane (50%) "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" HLEGFLMGVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.3%) GO:0005829 (20.3%) "GO:0004832 (20.3%) GO:0005524 (20.3%) GO:0002161 (19%)" valyl-tRNA aminoacylation (20.3%) cytosol (20.3%) "valine-tRNA ligase activity (20.3%) ATP binding (20.3%) aminoacyl-tRNA deacylase activity (19%)" "IPR001412 (9.4%) IPR002300 (9.4%) IPR002303 (9.4%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.4%) Aminoacyl-tRNA synthetase, class Ia (9.4%) Valine-tRNA ligase (9.4%)" VLLNLVVR root "GO:0006808 (5.1%) GO:0006886 (2.8%) GO:0006888 (2.8%)" "GO:0005886 (11.2%) GO:0005829 (5.1%) GO:0005737 (4.5%)" "GO:0005388 (8.4%) GO:0005524 (5.6%) GO:0030234 (5.1%)" "regulation of nitrogen utilization (5.1%) intracellular protein transport (2.8%) endoplasmic reticulum to Golgi vesicle-mediated transport (2.8%)" "plasma membrane (11.2%) cytosol (5.1%) cytoplasm (4.5%)" "P-type calcium transporter activity (8.4%) ATP binding (5.6%) enzyme regulator activity (5.1%)" "IPR006068 (6.5%) IPR008250 (6.5%) IPR023298 (6.5%)" "Cation-transporting P-type ATPase, C-terminal (6.5%) P-type ATPase, A domain superfamily (6.5%) P-type ATPase, transmembrane domain superfamily (6.5%)" ATWNLGADLGLWNNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (2.8%) GO:0009279 (94.4%) GO:0015344 (2.8%) siderophore transmembrane transport (2.8%) cell outer membrane (94.4%) siderophore uptake transmembrane transporter activity (2.8%) "IPR000531 (14.9%) IPR039426 (14.9%) IPR036942 (14.5%)" "TonB-dependent receptor-like, beta-barrel (14.9%) TonB-dependent receptor-like (14.9%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%)" MSVFSLDAAYVVATAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" ENDEVLDEVVVVGYAVGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR037066 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent receptor, plug domain superfamily (13%)" SEYYDLGLPYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.3%) GO:0006102 (20.3%)" "GO:0004450 (20.3%) GO:0000287 (18.8%) GO:0051287 (18.8%)" "tricarboxylic acid cycle (20.3%) isocitrate metabolic process (20.3%)" "isocitrate dehydrogenase (NADP+) activity (20.3%) magnesium ion binding (18.8%) NAD binding (18.8%)" "IPR004790 (34.2%) IPR024084 (34.2%) IPR019818 (31.6%)" "Isocitrate dehydrogenase NADP-dependent (34.2%) Isopropylmalate dehydrogenase-like domain (34.2%) Isocitrate/isopropylmalate dehydrogenase, conserved site (31.6%)" EELSAAYHAGANYGLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (32%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (32%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" MDTNSPNVAQGGTYTELSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036777 (100%) Nucleoside-specific channel-forming protein, Tsx-like superfamily (100%) KMGGMTFVDLR Bacteria Bacteria 6.1.1.12 (100%) aspartate--tRNA ligase (100%) "GO:0006422 (19.9%) GO:0006430 (0.3%)" GO:0005737 (19.7%) "GO:0003676 (19.9%) GO:0004815 (19.9%) GO:0005524 (19.9%)" "aspartyl-tRNA aminoacylation (19.9%) lysyl-tRNA aminoacylation (0.3%)" cytoplasm (19.7%) "nucleic acid binding (19.9%) aspartate-tRNA ligase activity (19.9%) ATP binding (19.9%)" "IPR004365 (9.2%) IPR012340 (9.2%) IPR047089 (9.2%)" "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (9.2%) Nucleic acid-binding, OB-fold (9.2%) Aspartate-tRNA ligase, type 1, anticodon recognition domain (9.2%)" DATSMVFSPDEGFNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025381 (100%) Domain of unknown function DUF4296 (100%) NKVTYLPATTTGAYAHTSTENLVQSGK Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GNDTLNDLELSLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.1.1.190 (96.2%) 2.1.1.- (3.8%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (96.2%) Methyltransferases (3.8%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR010280 (17.4%) IPR030390 (17.4%) IPR002792 (16.8%)" "(Uracil-5)-methyltransferase family (17.4%) RNA methyltransferase TrmA, active site (17.4%) TRAM domain (16.8%)" ATTELRPLWCEVSPLPMPHGSALFQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.9%) IPR003029 (7.9%) IPR004087 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) S1 domain (7.9%) K Homology domain (7.9%)" LFTYSELLLNYAEALNEADYAGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" GLLPNAQFYDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.4.16.4 (88.5%) 2.4.1.129 (11.5%)" "serine-type D-Ala-D-Ala carboxypeptidase (88.5%) Transferred entry: 2.4.99.28 (11.5%)" "GO:0071555 (14.6%) GO:0009252 (14.3%) GO:0008360 (14.1%)" GO:0005886 (14.6%) "GO:0008658 (14.6%) GO:0071972 (14.6%) GO:0009002 (12%)" "cell wall organization (14.6%) peptidoglycan biosynthetic process (14.3%) regulation of cell shape (14.1%)" plasma membrane (14.6%) "penicillin binding (14.6%) peptidoglycan L,D-transpeptidase activity (14.6%) serine-type D-Ala-D-Ala carboxypeptidase activity (12%)" "IPR001460 (17.3%) IPR050515 (17.3%) IPR012338 (17.2%)" "Penicillin-binding protein, transpeptidase (17.3%) Class D beta-lactamase/transpeptidase (17.3%) Beta-lactamase/transpeptidase-like (17.2%)" DLPNLDLLEQAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025324 (100%) Protein of unknown function DUF4230 (100%) LKDESLYHER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (36.4%) "GO:0004556 (31.8%) GO:0043169 (31.8%)" carbohydrate metabolic process (36.4%) "alpha-amylase activity (31.8%) cation binding (31.8%)" "IPR006047 (18.2%) IPR031965 (18.2%) IPR006046 (15.9%)" "Glycosyl hydrolase family 13, catalytic domain (18.2%) Starch-binding module 26 (18.2%) Alpha amylase (15.9%)" ENQGNFYLDHVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.2.1.22 (97.4%) 3.2.1.- (2.6%)" "alpha-galactosidase (97.4%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.6%)" GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR050985 (12.9%) IPR013785 (12.6%)" "Glycoside hydrolase family 36 (12.9%) Alpha-glycosidase and related enzymes (12.9%) Aldolase-type TIM barrel (12.6%)" VGMVAVHLYRPFSVDFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.4%) GO:0022900 (14.4%) GO:0044281 (13.5%)" "GO:0005506 (14.4%) GO:0030976 (14.4%) GO:0051539 (14.4%)" "response to oxidative stress (14.4%) electron transport chain (14.4%) small molecule metabolic process (13.5%)" "iron ion binding (14.4%) thiamine pyrophosphate binding (14.4%) 4 iron, 4 sulfur cluster binding (14.4%)" "IPR002869 (7.7%) IPR002880 (7.7%) IPR009014 (7.7%)" "Pyruvate-flavodoxin oxidoreductase, central domain (7.7%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.7%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (7.7%)" HVTFDELYDLLAVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.1.7.2 (66.7%) 2.7.6.5 (33.3%)" "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (66.7%) GTP diphosphokinase (33.3%)" GO:0015969 (42.1%) GO:0005886 (42.1%) "GO:0016787 (8.4%) GO:0016301 (5.6%) GO:0008893 (1.9%)" guanosine tetraphosphate metabolic process (42.1%) plasma membrane (42.1%) "hydrolase activity (8.4%) kinase activity (5.6%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (1.9%)" "IPR007685 (9.4%) IPR002912 (9.2%) IPR003607 (9.2%)" "RelA/SpoT (9.4%) ACT domain (9.2%) HD/PDEase domain (9.2%)" EFQAMGGTLNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (45.5%) "GO:0004650 (45.5%) GO:0004557 (9.1%)" carbohydrate metabolic process (45.5%) "polygalacturonase activity (45.5%) alpha-galactosidase activity (9.1%)" "IPR000743 (20.8%) IPR006626 (20.8%) IPR051801 (20.8%)" "Glycoside hydrolase, family 28 (20.8%) Parallel beta-helix repeat (20.8%) Glycosyl_Hydrolase_28_Enzymes (20.8%)" LTYDFQYTLESLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ELNPNYPLEAEAGHNFFSAGNYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.6%) IPR011990 (47.4%)" "Tetratricopeptide repeat (52.6%) Tetratricopeptide-like helical domain superfamily (47.4%)" TLADNGSSLLFTLGAEHLSDNGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (30%) GO:0009279 (40%) GO:0015344 (30%) siderophore transmembrane transport (30%) cell outer membrane (40%) siderophore uptake transmembrane transporter activity (30%) "IPR000531 (45.3%) IPR036942 (31.3%) IPR039426 (23.4%)" "TonB-dependent receptor-like, beta-barrel (45.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (31.3%) TonB-dependent receptor-like (23.4%)" NATYDDCVFDMMNLFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021457 (100%) Protein of unknown function DUF3108 (100%) KLGASCDWDR root "6.1.1.9 (99.9%) 4.2.1.47 (0.1%)" "valine--tRNA ligase (99.9%) GDP-mannose 4,6-dehydratase (0.1%)" "GO:0006438 (20%) GO:0006508 (0%) GO:0042351 (0%)" "GO:0005829 (20%) GO:0016020 (0%)" "GO:0004832 (20%) GO:0005524 (20%) GO:0002161 (19.8%)" "valyl-tRNA aminoacylation (20%) proteolysis (0%) 'de novo' GDP-L-fucose biosynthetic process (0%)" "cytosol (20%) membrane (0%)" "valine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.8%)" "IPR002300 (9.2%) IPR002303 (9.2%) IPR014729 (9.2%)" "Aminoacyl-tRNA synthetase, class Ia (9.2%) Valine-tRNA ligase (9.2%) Rossmann-like alpha/beta/alpha sandwich fold (9.2%)" NKPLNTYVTQVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (25%) GO:0003700 (25%) GO:0005524 (25%)" "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) ATP binding (25%)" "IPR001789 (7.2%) IPR003594 (7.2%) IPR003661 (7.2%)" "Signal transduction response regulator, receiver domain (7.2%) Histidine kinase/HSP90-like ATPase domain (7.2%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.2%)" QLLSSGVNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.2%) "GO:0005524 (25.2%) GO:0042802 (24.3%) GO:0004713 (17.1%)" plasma membrane (25.2%) "ATP binding (25.2%) identical protein binding (24.3%) protein tyrosine kinase activity (17.1%)" "IPR005702 (16.9%) IPR025669 (16.9%) IPR032807 (16.9%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (16.9%) AAA domain (16.9%) Tyrosine-protein kinase, G-rich domain (16.9%)" ALELMNQCDLHYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006261 (16.9%) GO:0009360 (16.9%) "GO:0003887 (16.9%) GO:0005524 (16.9%) GO:0046872 (16.9%)" DNA-templated DNA replication (16.9%) DNA polymerase III complex (16.9%) "DNA-directed DNA polymerase activity (16.9%) ATP binding (16.9%) metal ion binding (16.9%)" "IPR003593 (12.9%) IPR012763 (12.9%) IPR022754 (12.9%)" "AAA+ ATPase domain (12.9%) DNA polymerase III, subunit gamma/ tau, N-terminal (12.9%) DNA polymerase III, gamma subunit, domain III (12.9%)" TAFPQEATDGCEVTDVEELAGQGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) GO:0005886 (16.7%) "GO:0005524 (16.7%) GO:0015086 (16.7%) GO:0016887 (16.7%)" plasma membrane (16.7%) "ATP binding (16.7%) cadmium ion transmembrane transporter activity (16.7%) ATP hydrolysis activity (16.7%)" "IPR001757 (10.4%) IPR018303 (10.4%) IPR027256 (10.4%)" "P-type ATPase (10.4%) P-type ATPase, phosphorylation site (10.4%) P-type ATPase, subfamily IB (10.4%)" LAYTVSYNHDTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.1.30.- (96.8%) 3.-.-.- (3.2%)" "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (96.8%) Hydrolases (3.2%)" "GO:0003676 (25%) GO:0004519 (25%) GO:0016787 (25%)" "nucleic acid binding (25%) endonuclease activity (25%) hydrolase activity (25%)" "IPR001604 (16.8%) IPR018524 (16.8%) IPR020821 (16.8%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (16.8%) DNA/RNA non-specific endonuclease, active site (16.8%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (16.8%)" KGFLQTPFNTPWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.8%) GO:0016787 (48.2%)" "carbohydrate binding (51.8%) hydrolase activity (48.2%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" HYREELAELK Bacteria Bacteria 6.1.1.19 (100%) arginine--tRNA ligase (100%) "GO:0006420 (24.3%) GO:0006355 (0.9%)" GO:0005737 (24.3%) "GO:0005524 (25.2%) GO:0004814 (24.3%) GO:0003677 (0.9%)" "arginyl-tRNA aminoacylation (24.3%) regulation of DNA-templated transcription (0.9%)" cytoplasm (24.3%) "ATP binding (25.2%) arginine-tRNA ligase activity (24.3%) DNA binding (0.9%)" "IPR001278 (12.3%) IPR001412 (12.3%) IPR005148 (12.3%)" "Arginine-tRNA ligase (12.3%) Aminoacyl-tRNA synthetase, class I, conserved site (12.3%) Arginyl tRNA synthetase N-terminal domain (12.3%)" ALQTFFSEGPGQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.5.1 (100%) dGTPase (100%) GO:0006203 (50%) GO:0008832 (50%) dGTP catabolic process (50%) dGTPase activity (50%) "IPR006261 (14.8%) IPR006674 (14.8%) IPR050135 (14.8%)" "dGTP triphosphohydrolase (14.8%) HD domain (14.8%) Deoxyguanosinetriphosphate triphosphohydrolase-like (14.8%)" SGDEVPSWASVSPESGEAGDKLSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (25%) IPR024361 (25%) IPR032339 (25%)" "Immunoglobulin-like fold (25%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (25%) Domain of unknown function DUF4859 (25%)" AVEETMANVAGQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17.1%) GO:0045259 (17.1%)" "GO:0005524 (17.1%) GO:0043531 (17.1%) GO:0046933 (17.1%)" "plasma membrane (17.1%) proton-transporting ATP synthase complex (17.1%)" "ATP binding (17.1%) ADP binding (17.1%) proton-transporting ATP synthase activity, rotational mechanism (17.1%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" FVHNMSFK Pseudomonadati Bacteria Pseudomonadati GO:0006313 (6.3%) GO:0009279 (81.3%) "GO:0003677 (6.3%) GO:0004803 (6.3%)" DNA transposition (6.3%) cell outer membrane (81.3%) "DNA binding (6.3%) transposase activity (6.3%)" "IPR012944 (31.7%) IPR033985 (31.7%) IPR011990 (29.3%)" "RagB/SusD domain (31.7%) SusD-like, N-terminal (31.7%) Tetratricopeptide-like helical domain superfamily (29.3%)" LSLTGLKEFAPGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.6%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.6%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" SAGAYGELMASQYNCR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.6%) "GO:0008836 (33.6%) GO:0030170 (32.9%)" lysine biosynthetic process via diaminopimelate (33.6%) "diaminopimelate decarboxylase activity (33.6%) pyridoxal phosphate binding (32.9%)" "IPR022643 (14.2%) IPR002986 (14.1%) IPR009006 (14.1%)" "Orn/DAP/Arg decarboxylase 2, C-terminal (14.2%) Diaminopimelate decarboxylase, LysA (14.1%) Alanine racemase/group IV decarboxylase, C-terminal (14.1%)" LLYDRTEDDEFVSFEPALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR015712 (8.5%) IPR007120 (8.1%) IPR007645 (8.1%)" "DNA-directed RNA polymerase, subunit 2 (8.5%) DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.1%) RNA polymerase Rpb2, domain 3 (8.1%)" NVDYVLPANDDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (33.3%) "GO:0022627 (29.6%) GO:0005840 (3.7%)" GO:0003735 (33.3%) translation (33.3%) "cytosolic small ribosomal subunit (29.6%) ribosome (3.7%)" structural constituent of ribosome (33.3%) "IPR001865 (26.5%) IPR023591 (26.5%) IPR005706 (23.5%)" "Small ribosomal subunit protein uS2 (26.5%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (26.5%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (23.5%)" LESLKQEMQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006310 (100%) DNA recombination (100%) IPR003798 (100%) DNA recombination RmuC (100%) SFVMGFPLECLLDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR003961 (25.8%) IPR033803 (25.8%) IPR013783 (24.2%)" "Fibronectin type III (25.8%) Golvesin/Xly, CBD-like (25.8%) Immunoglobulin-like fold (24.2%)" NVSFTDLK root "6.1.1.20 (98.8%) 3.6.4.13 (0.8%) 3.1.6.21 (0.4%)" "phenylalanine--tRNA ligase (98.8%) RNA helicase (0.8%) linear primary-alkylsulfatase (0.4%)" "GO:0006432 (16.2%) GO:0043107 (0.1%) GO:0043683 (0.1%)" "GO:0005737 (16.3%) GO:0016020 (0.6%) GO:0005829 (0.1%)" "GO:0005524 (16.3%) GO:0000049 (16.2%) GO:0004826 (16.2%)" "phenylalanyl-tRNA aminoacylation (16.2%) type IV pilus-dependent motility (0.1%) type IV pilus assembly (0.1%)" "cytoplasm (16.3%) membrane (0.6%) cytosol (0.1%)" "ATP binding (16.3%) tRNA binding (16.2%) phenylalanine-tRNA ligase activity (16.2%)" "IPR002319 (13.9%) IPR006195 (13.9%) IPR045864 (13.9%)" "Phenylalanyl-tRNA synthetase (13.9%) Aminoacyl-tRNA synthetase, class II (13.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (13.9%)" FDEDDYVVNLGPNHPSTHGVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.6.5.11 (66.7%) 1.6.5.9 (33.3%)" "Transferred entry: 1.6.5.9 (66.7%) NADH:ubiquinone reductase (non-electrogenic) (33.3%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" LLEAGCKPQEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.148 (100%) thymidylate synthase (FAD) (100%) "GO:0006231 (18.3%) GO:0032259 (8.7%)" "GO:0004799 (18.3%) GO:0050660 (18.3%) GO:0050797 (18.3%)" "dTMP biosynthetic process (18.3%) methylation (8.7%)" "thymidylate synthase activity (18.3%) flavin adenine dinucleotide binding (18.3%) thymidylate synthase (FAD) activity (18.3%)" "IPR003669 (52.8%) IPR036098 (47.2%)" "Thymidylate synthase ThyX (52.8%) Thymidylate synthase ThyX superfamily (47.2%)" DLVTWSHGSSDVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025632 (100%) Protein of unknown function DUF4290 (100%) EGEYMVLTLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.14 (100%) UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) (100%) "GO:0016853 (90%) GO:0008761 (10%)" "isomerase activity (90%) UDP-N-acetylglucosamine 2-epimerase activity (10%)" "IPR003331 (50%) IPR029767 (50%)" "UDP-N-acetylglucosamine 2-epimerase domain (50%) UDP-N-acetylglucosamine 2-epimerase WecB-like (50%)" HFLEYYYDAYDLALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) YAHVTFFFNGGR root "5.4.2.12 (99.9%) 5.4.2.1 (0.1%)" "phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (99.9%) Transferred entry: 5.4.2.11 and 5.4.2.12 (0.1%)" "GO:0006007 (19.7%) GO:0006096 (19.7%) GO:0019287 (0.3%)" "GO:0005829 (16.6%) GO:0005737 (3.1%) GO:0005839 (0%)" "GO:0004619 (19.7%) GO:0030145 (19.7%) GO:0004496 (0.3%)" "glucose catabolic process (19.7%) glycolytic process (19.7%) isopentenyl diphosphate biosynthetic process, mevalonate pathway (0.3%)" "cytosol (16.6%) cytoplasm (3.1%) proteasome core complex (0%)" "phosphoglycerate mutase activity (19.7%) manganese ion binding (19.7%) mevalonate kinase activity (0.3%)" "IPR005995 (19.6%) IPR006124 (19.6%) IPR017850 (19.6%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (19.6%) Metalloenzyme (19.6%) Alkaline-phosphatase-like, core domain superfamily (19.6%)" PQVGFQNVPTGLASSYLFSLKPGDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.9%) "GO:0005886 (16.1%) GO:0016020 (0.8%)" "GO:0016655 (16.9%) GO:0051537 (16.9%) GO:0009055 (16.1%)" sodium ion transport (16.9%) "plasma membrane (16.1%) membrane (0.8%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.9%) 2 iron, 2 sulfur cluster binding (16.9%) electron transfer activity (16.1%)" "IPR001433 (10.1%) IPR001709 (10.1%) IPR008333 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" VGLFRPLTLWPFPEK Bacteria Bacteria "1.2.7.7 (58.3%) 1.2.-.- (25%) 1.2.7.11 (8.3%)" "3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (58.3%) Acting on the aldehyde or oxo group of donors (25%) 2-oxoacid oxidoreductase (ferredoxin) (8.3%)" "GO:0016491 (92.6%) GO:0043807 (7.4%)" "oxidoreductase activity (92.6%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity (7.4%)" "IPR002880 (20.1%) IPR033412 (20.1%) IPR052368 (20.1%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (20.1%) Pyruvate:ferredoxin oxidoreductase, core domain II (20.1%) 2-oxoacid oxidoreductase subunit (20.1%)" KLLQWYNLLAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "IPR041218 (26.2%) IPR049280 (26.2%) IPR049281 (23.8%)" "Domain of unknown function DUF5606 (26.2%) Domain of unknown function DUF6852 (26.2%) BVU_3817-like, C-terminal domain superfamily (23.8%)" VVNSSLLK root "2.7.1.170 (20%) 2.7.7.49 (20%) 2.7.7.52 (20%)" "anhydro-N-acetylmuramic acid kinase (20%) RNA-directed DNA polymerase (20%) RNA uridylyltransferase (20%)" "GO:0044718 (7.4%) GO:0006457 (2.1%) GO:0055070 (2.1%)" "GO:0009279 (8.5%) GO:0005634 (4.3%) GO:0016020 (4.3%)" "GO:0015344 (7.4%) GO:0005524 (6.4%) GO:0008270 (5.3%)" "siderophore transmembrane transport (7.4%) protein folding (2.1%) copper ion homeostasis (2.1%)" "cell outer membrane (8.5%) nucleus (4.3%) membrane (4.3%)" "siderophore uptake transmembrane transporter activity (7.4%) ATP binding (6.4%) zinc ion binding (5.3%)" "IPR057601 (5.8%) IPR036942 (5%) IPR039426 (5%)" "TonB-dependent transporter Oar-like, beta-barrel domain (5.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (5%) TonB-dependent receptor-like (5%)" LKNFGENTYPEMLLALAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (16.7%) GO:0007165 (16.7%)" "GO:0030288 (16.7%) GO:0016020 (16.3%)" "GO:0004175 (16.7%) GO:0008236 (16.7%)" "proteolysis (16.7%) signal transduction (16.7%)" "outer membrane-bounded periplasmic space (16.7%) membrane (16.3%)" "endopeptidase activity (16.7%) serine-type peptidase activity (16.7%)" "IPR001478 (20.4%) IPR004447 (20.4%) IPR005151 (20.4%)" "PDZ domain (20.4%) C-terminal-processing peptidase S41A (20.4%) Tail specific protease (20.4%)" EGLLYCSLEYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.4%) IPR019826 (20.4%) IPR050309 (20.4%)" "Carboxylesterase, type B (20.4%) Carboxylesterase type B, active site (20.4%) Type-B Carboxylesterase/Lipase (20.4%)" ELSVSAGFGLPLMNAYNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GETMSLSTCTLGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR001247 (7.9%) IPR004088 (7.9%) IPR012162 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) K Homology domain, type 1 (7.9%) Polyribonucleotide nucleotidyltransferase (7.9%)" WYEGQVAVNDWNDDGKLDDNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NLWMVEK root "GO:0045892 (1.9%) GO:0006508 (0.5%)" "GO:0016020 (1.4%) GO:0000323 (0.5%) GO:0005886 (0.5%)" "GO:0016787 (50.9%) GO:0003677 (37.3%) GO:0003700 (2.8%)" "negative regulation of DNA-templated transcription (1.9%) proteolysis (0.5%)" "membrane (1.4%) lytic vacuole (0.5%) plasma membrane (0.5%)" "hydrolase activity (50.9%) DNA binding (37.3%) DNA-binding transcription factor activity (2.8%)" "IPR052567 (33.2%) IPR006674 (25.2%) IPR001647 (12%)" "Organophosphonate Dioxygenase (33.2%) HD domain (25.2%) DNA-binding HTH domain, TetR-type (12%)" WAPFEGASSYNVYVDDKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000272 (30.5%) GO:0005576 (30.5%) "GO:0030570 (30.5%) GO:0004557 (6.8%) GO:0016829 (1.7%)" polysaccharide catabolic process (30.5%) extracellular region (30.5%) "pectate lyase activity (30.5%) alpha-galactosidase activity (6.8%) lyase activity (1.7%)" "IPR002022 (19%) IPR011050 (18%) IPR012334 (18%)" "Pectate lyase (19%) Pectin lyase fold/virulence factor (18%) Pectin lyase fold (18%)" LCEMSPQVVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR000595 (37.5%) IPR014710 (31.3%) IPR018490 (31.3%)" "Cyclic nucleotide-binding domain (37.5%) RmlC-like jelly roll fold (31.3%) Cyclic nucleotide-binding domain superfamily (31.3%)" GYASNEDLYVPGYFEMDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.4%) IPR024742 (20.4%) IPR032790 (20.4%)" "Glycogen debranching enzyme (20.4%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.4%) Glycogen debranching enzyme, C-terminal (20.4%)" SLLQMMSMGGEGSLLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) TSADYDGSMDSFGAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EHYDYVLLDTAPVGLVNDSLQLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.2%) "GO:0005524 (25.2%) GO:0042802 (24.3%) GO:0004713 (20.6%)" plasma membrane (25.2%) "ATP binding (25.2%) identical protein binding (24.3%) protein tyrosine kinase activity (20.6%)" "IPR005702 (16.9%) IPR025669 (16.9%) IPR032807 (16.9%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (16.9%) AAA domain (16.9%) Tyrosine-protein kinase, G-rich domain (16.9%)" LAMQVAAMRPVALDESSVSEETK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (50%) GO:0003746 (50%) cytoplasm (50%) translation elongation factor activity (50%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" AAVPSLLDSGLDKELFEYELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0008654 (20%) GO:0005886 (20%) "GO:0005524 (20%) GO:0016301 (20%) GO:0046872 (20%)" phospholipid biosynthetic process (20%) plasma membrane (20%) "ATP binding (20%) kinase activity (20%) metal ion binding (20%)" "IPR001206 (16.7%) IPR005218 (16.7%) IPR016064 (16.7%)" "Diacylglycerol kinase, catalytic domain (16.7%) Diacylglycerol/lipid kinase (16.7%) NAD kinase/diacylglycerol kinase-like domain superfamily (16.7%)" SLNPEWK root "6.3.5.4 (42.9%) 2.7.11.13 (14.3%) 3.1.21.- (14.3%)" "asparagine synthase (glutamine-hydrolyzing) (42.9%) protein kinase C (14.3%) Endodeoxyribonucleases producing 5'-phosphomonoesters (14.3%)" "GO:0006654 (10.4%) GO:0016255 (4.3%) GO:0006897 (2.5%)" "GO:0042765 (4.5%) GO:0005902 (2.7%) GO:0016459 (2.7%)" "GO:0003841 (10.4%) GO:0005524 (3.6%) GO:0000146 (2.5%)" "phosphatidic acid biosynthetic process (10.4%) attachment of GPI anchor to protein (4.3%) endocytosis (2.5%)" "GPI-anchor transamidase complex (4.5%) microvillus (2.7%) myosin complex (2.7%)" "1-acylglycerol-3-phosphate O-acyltransferase activity (10.4%) ATP binding (3.6%) microfilament motor activity (2.5%)" "IPR002123 (11.2%) IPR000008 (5.4%) IPR035892 (5.4%)" "Phospholipid/glycerol acyltransferase (11.2%) C2 domain (5.4%) C2 domain superfamily (5.4%)" LDVDEAYADPYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FSYNTSLSAFMLAVNELGQQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) "GO:0005829 (20%) GO:0005739 (0.4%)" "GO:0004823 (20%) GO:0005524 (20%) GO:0002161 (19.6%)" leucyl-tRNA aminoacylation (20%) "cytosol (20%) mitochondrion (0.4%)" "leucine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.6%)" "IPR002300 (12.8%) IPR002302 (12.8%) IPR013155 (12.8%)" "Aminoacyl-tRNA synthetase, class Ia (12.8%) Leucine-tRNA ligase (12.8%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.8%)" FGVHDLDLMAGAEQSHFHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" NGLPEFDDYNKTCDYPVNGEPNSQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EGCELLNEPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006813 (6%) GO:0005886 (44%) "GO:0015079 (44%) GO:0008324 (6%)" potassium ion transport (6%) plasma membrane (44%) "potassium ion transmembrane transporter activity (44%) monoatomic cation transmembrane transporter activity (6%)" "IPR003148 (17.7%) IPR006037 (17.7%) IPR050721 (17.7%)" "Regulator of K+ conductance, N-terminal lobe (17.7%) Regulator of K+ conductance, C-terminal (17.7%) Trk/Ktr/HKT Potassium Transport (17.7%)" YGLPNFK root "1.4.1.13 (77.4%) 1.4.1.14 (13.6%) 1.4.1.- (7.2%)" "glutamate synthase (NADPH) (77.4%) glutamate synthase (NADH) (13.6%) With NAD(+) or NADP(+) as acceptor (7.2%)" "GO:0006537 (23%) GO:0034605 (0.4%) GO:0042026 (0.4%)" "GO:0005759 (0.4%) GO:0005886 (0.2%) GO:0016020 (0.1%)" "GO:0051536 (24.3%) GO:0016639 (23%) GO:0046872 (8.6%)" "glutamate biosynthetic process (23%) cellular response to heat (0.4%) protein refolding (0.4%)" "mitochondrial matrix (0.4%) plasma membrane (0.2%) membrane (0.1%)" "iron-sulfur cluster binding (24.3%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (23%) metal ion binding (8.6%)" "IPR036188 (16.3%) IPR023753 (16.2%) IPR028261 (16.2%)" "FAD/NAD(P)-binding domain superfamily (16.3%) FAD/NAD(P)-binding domain (16.2%) Dihydroprymidine dehydrogenase domain II (16.2%)" QLPYHLLDLCEPGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.75 (100%) tRNA dimethylallyltransferase (100%) GO:0006400 (33.7%) "GO:0052381 (33.7%) GO:0005524 (32.5%)" tRNA modification (33.7%) "tRNA dimethylallyltransferase activity (33.7%) ATP binding (32.5%)" "IPR039657 (34.6%) IPR018022 (33.3%) IPR027417 (32.1%)" "Dimethylallyltransferase (34.6%) IPP transferase (33.3%) P-loop containing nucleoside triphosphate hydrolase (32.1%)" WNQVVTNVDEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" xylan catabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (17.2%) IPR006584 (17.2%) IPR006710 (17.2%)" "Carbohydrate binding module family 6 (17.2%) Cellulose binding, type IV (17.2%) Glycoside hydrolase, family 43 (17.2%)" NLGEGNYDFENLNNNHVGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016485 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) protein processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000209 (16.9%) IPR022398 (16.9%) IPR023828 (16.9%)" "Peptidase S8/S53 domain (16.9%) Peptidase S8, subtilisin, His-active site (16.9%) Peptidase S8, subtilisin, Ser-active site (16.9%)" TVYNDLLKDLNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (50%) GO:0016788 (47%) GO:0016787 (3%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (47%) hydrolase activity (3%)" "IPR000801 (17.2%) IPR005181 (17.2%) IPR050583 (17.2%)" "Esterase-like (17.2%) Sialate O-acetylesterase domain (17.2%) Mycobacterial A85 antigen (17.2%)" AEMKPQVPR Bacteria Bacteria 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.9%) IPR003029 (7.9%) IPR004087 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) S1 domain (7.9%) K Homology domain (7.9%)" KLLDDAVDQLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (44.3%) "GO:0004650 (44.3%) GO:0004557 (11.5%)" carbohydrate metabolic process (44.3%) "polygalacturonase activity (44.3%) alpha-galactosidase activity (11.5%)" "IPR000743 (13%) IPR006626 (13%) IPR010905 (13%)" "Glycoside hydrolase, family 28 (13%) Parallel beta-helix repeat (13%) Glycosyl hydrolase, family 88 (13%)" ALFNLDTALLKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003497 (100%) BRO N-terminal domain (100%) LNYAATLQLTYNLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.2%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.2%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" EHLSAFLFPSTDAHQSEYVADHWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (24.3%) GO:0005737 (24.3%) "GO:0046872 (25.7%) GO:0070006 (24.3%) GO:0016787 (1.4%)" proteolysis (24.3%) cytoplasm (24.3%) "metal ion binding (25.7%) metalloaminopeptidase activity (24.3%) hydrolase activity (1.4%)" "IPR000587 (13.1%) IPR050422 (13.1%) IPR000994 (12.4%)" "Creatinase, N-terminal (13.1%) Xaa-Pro aminopeptidase P (13.1%) Peptidase M24 (12.4%)" YYLSDDGTTNNQFYVYNGYAGPNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AETDSFGLLSGNGLPFPYELVCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) FVNHSDVAGGSTLGNLLASSLPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.6%) GO:0005737 (19%) "GO:0004177 (20.6%) GO:0008270 (20.6%) GO:0008237 (19%)" proteolysis (20.6%) cytoplasm (19%) "aminopeptidase activity (20.6%) zinc ion binding (20.6%) metallopeptidase activity (19%)" "IPR001948 (52%) IPR023358 (48%)" "Peptidase M18 (52%) Peptidase M18, domain 2 (48%)" GFTFTSR root "2.7.11.1 (50%) 5.6.2.3 (25%) 5.6.2.4 (25%)" "non-specific serine/threonine protein kinase (50%) DNA 5'-3' helicase (25%) DNA 3'-5' helicase (25%)" "GO:0000379 (6%) GO:0006511 (1.7%) GO:0000723 (0.9%)" "GO:0009279 (41.4%) GO:0000214 (6%) GO:0005737 (1.7%)" "GO:0004519 (6%) GO:0005524 (4.3%) GO:0016887 (2.6%)" "tRNA-type intron splice site recognition and cleavage (6%) ubiquitin-dependent protein catabolic process (1.7%) telomere maintenance (0.9%)" "cell outer membrane (41.4%) tRNA-intron endonuclease complex (6%) cytoplasm (1.7%)" "endonuclease activity (6%) ATP binding (4.3%) ATP hydrolysis activity (2.6%)" "IPR023996 (9.4%) IPR036942 (9.4%) IPR008969 (9.2%)" "TonB-dependent outer membrane protein, SusC/RagA (9.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (9.4%) Carboxypeptidase-like, regulatory domain superfamily (9.2%)" GNYTLGLTEQLLFPELNLDELDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" AFPAALLNDALNTGK Bacteria Bacteria 1.1.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013131 (17.1%) IPR050988 (17.1%) IPR013118 (16.8%)" "Mannitol dehydrogenase, N-terminal (17.1%) Mannitol Dehydrogenase/Oxidoreductase (17.1%) Mannitol dehydrogenase, C-terminal (16.8%)" QYNCNLNDEEVAAAVKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" GEVNSVLSTSYPYNAPDLGLCDVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (25%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (25%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR011110 (12.5%) IPR011123 (12.5%) IPR018060 (12.5%)" "Two component regulator propeller (12.5%) Two component regulator three Y (12.5%) AraC-like, DNA binding HTH domain (12.5%)" MHLLGNVVAWGDDNPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR010720 (14.5%) IPR051563 (14.5%) IPR055235 (14.5%)" "Alpha-L-arabinofuranosidase, C-terminal (14.5%) Glycosyl Hydrolase Family 51 (14.5%) Alpha-L-arabinofuranosidase 1, catalytic domain (14.5%)" NVYQLQAK root "2.5.1.7 (67.6%) 2.7.7.49 (20.6%) 6.1.1.15 (8.8%)" "UDP-N-acetylglucosamine 1-carboxyvinyltransferase (67.6%) RNA-directed DNA polymerase (20.6%) proline--tRNA ligase (8.8%)" "GO:0008360 (11.1%) GO:0009252 (11.1%) GO:0019277 (11.1%)" "GO:0005737 (11.1%) GO:0042575 (2.5%) GO:0005829 (0.5%)" "GO:0008760 (11.1%) GO:0003676 (3.5%) GO:0008270 (3%)" "regulation of cell shape (11.1%) peptidoglycan biosynthetic process (11.1%) UDP-N-acetylgalactosamine biosynthetic process (11.1%)" "cytoplasm (11.1%) DNA polymerase complex (2.5%) cytosol (0.5%)" "UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (11.1%) nucleic acid binding (3.5%) zinc ion binding (3%)" "IPR001986 (10.3%) IPR005750 (10.3%) IPR013792 (10.3%)" "Enolpyruvate transferase domain (10.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (10.3%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (10.3%)" KAAEVFGELLTLVEGGQTQYGLAEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.5%) IPR011990 (32.3%) IPR012944 (32.3%)" "SusD-like, N-terminal (35.5%) Tetratricopeptide-like helical domain superfamily (32.3%) RagB/SusD domain (32.3%)" QGDYHTWVTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (38.2%) IPR012944 (38.2%) IPR033985 (23.5%)" "Tetratricopeptide-like helical domain superfamily (38.2%) RagB/SusD domain (38.2%) SusD-like, N-terminal (23.5%)" FNDVQKDQTYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" LDSVEVLGFVDNNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.6%) IPR002034 (14.6%) IPR013709 (14.6%)" "Pyruvate carboxyltransferase (14.6%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.6%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.6%)" MTFENLLPDQHLLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016036 (20%) GO:0005886 (20%) "GO:0000155 (20%) GO:0004721 (20%) GO:0005524 (20%)" cellular response to phosphate starvation (20%) plasma membrane (20%) "phosphorelay sensor kinase activity (20%) phosphoprotein phosphatase activity (20%) ATP binding (20%)" "IPR003594 (14.8%) IPR003661 (14.8%) IPR005467 (14.8%)" "Histidine kinase/HSP90-like ATPase domain (14.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (14.8%) Histidine kinase domain (14.8%)" FFQMLEETLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) MEEELLQPLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006629 (50%) GO:0016746 (50%) lipid metabolic process (50%) acyltransferase activity (50%) "IPR052351 (52.5%) IPR016181 (47.5%)" "L-ornithine N(alpha)-acyltransferase (52.5%) Acyl-CoA N-acyltransferase (47.5%)" HVFTPTVSFSYAPDFGASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (50%) GO:1990351 (50%)" "cell outer membrane (50%) transporter complex (50%)" "IPR045659 (50%) IPR050218 (50%)" "LPS-assembly protein LptD, central domain (50%) Lipopolysaccharide Assembly Protein LptD (50%)" LRAESDQQWAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006310 (100%) DNA recombination (100%) IPR003798 (100%) DNA recombination RmuC (100%) TAYLSSALDLLFAAQR Pseudomonadati Bacteria Pseudomonadati IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) GLNYAAPLR Pseudomonadati Bacteria Pseudomonadati "2.7.13.3 (94.6%) 2.7.7.6 (5.4%)" "histidine kinase (94.6%) DNA-directed RNA polymerase (5.4%)" GO:0006351 (1.3%) "GO:0016020 (22%) GO:0000428 (1.3%)" "GO:0000155 (22%) GO:0003700 (22%) GO:0043565 (22%)" DNA-templated transcription (1.3%) "membrane (22%) DNA-directed RNA polymerase complex (1.3%)" "phosphorelay sensor kinase activity (22%) DNA-binding transcription factor activity (22%) sequence-specific DNA binding (22%)" "IPR001789 (6.3%) IPR003594 (6.3%) IPR003661 (6.3%)" "Signal transduction response regulator, receiver domain (6.3%) Histidine kinase/HSP90-like ATPase domain (6.3%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.3%)" QEDLDNEDVLLQVENTPTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000917 (13.9%) GO:0043093 (13.9%) GO:0051258 (13.9%)" "GO:0005737 (13.9%) GO:0032153 (13.9%)" "GO:0005525 (15.3%) GO:0003924 (13.9%)" "division septum assembly (13.9%) FtsZ-dependent cytokinesis (13.9%) protein polymerization (13.9%)" "cytoplasm (13.9%) cell division site (13.9%)" "GTP binding (15.3%) GTPase activity (13.9%)" "IPR024757 (12.6%) IPR000158 (11.5%) IPR003008 (11.5%)" "Cell division protein FtsZ, C-terminal (12.6%) Cell division protein FtsZ (11.5%) Tubulin/FtsZ, GTPase domain (11.5%)" GYTDDDPSTNSFRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri STLLNQLGCLDTPSSGEYYLDGVSVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) GO:0005886 (10%) "GO:0005524 (40%) GO:0016887 (40%) GO:0022857 (10%)" plasma membrane (10%) "ATP binding (40%) ATP hydrolysis activity (40%) transmembrane transporter activity (10%)" "IPR003439 (19.8%) IPR027417 (19.8%) IPR003593 (18.5%)" "ABC transporter-like, ATP-binding domain (19.8%) P-loop containing nucleoside triphosphate hydrolase (19.8%) AAA+ ATPase domain (18.5%)" AAMQEEPFFELGFDEPAKENEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" ANWGMLR root 3.2.1.22 (100%) alpha-galactosidase (100%) "GO:0016052 (42.9%) GO:0006412 (1.4%) GO:0009103 (1.4%)" "GO:0005840 (1.4%) GO:0005886 (1.4%) GO:0016020 (1.4%)" "GO:0004557 (42.9%) GO:0003723 (1.4%) GO:0003735 (1.4%)" "carbohydrate catabolic process (42.9%) translation (1.4%) lipopolysaccharide biosynthetic process (1.4%)" "ribosome (1.4%) plasma membrane (1.4%) membrane (1.4%)" "alpha-galactosidase activity (42.9%) RNA binding (1.4%) structural constituent of ribosome (1.4%)" "IPR002252 (12.4%) IPR031704 (12.4%) IPR031705 (12.4%)" "Glycoside hydrolase family 36 (12.4%) Glycosyl hydrolase family 36, N-terminal (12.4%) Glycosyl hydrolase family 36, C-terminal (12.4%)" EDFSGTHNFAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.2.29 (100%) peptidoglycan lytic transglycosylase (100%) "GO:0071555 (24.9%) GO:0009252 (24.1%)" GO:0005886 (24.9%) "GO:0008932 (24.1%) GO:0016740 (1.2%) GO:0016829 (0.8%)" "cell wall organization (24.9%) peptidoglycan biosynthetic process (24.1%)" plasma membrane (24.9%) "lytic endotransglycosylase activity (24.1%) transferase activity (1.2%) lyase activity (0.8%)" IPR003770 (100%) Endolytic murein transglycosylase (100%) TLDVFENHAAFPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (16.8%) GO:0007165 (16.8%)" "GO:0030288 (16.8%) GO:0016020 (16.1%)" "GO:0004175 (16.8%) GO:0008236 (16.8%)" "proteolysis (16.8%) signal transduction (16.8%)" "outer membrane-bounded periplasmic space (16.8%) membrane (16.1%)" "endopeptidase activity (16.8%) serine-type peptidase activity (16.8%)" "IPR001478 (20.6%) IPR004447 (20.6%) IPR005151 (20.6%)" "PDZ domain (20.6%) C-terminal-processing peptidase S41A (20.6%) Tail specific protease (20.6%)" GLQDCYADLRK Bacteria Bacteria 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (25.2%) IPR043129 (25.2%) IPR050406 (25.2%)" "Carbohydrate kinase FGGY, N-terminal (25.2%) ATPase, nucleotide binding domain (25.2%) FGGY Carbohydrate Kinase (25.2%)" PLEGLQYR root GO:0098703 (10%) "GO:0009279 (70%) GO:0005886 (10%)" GO:0005216 (10%) calcium ion import across plasma membrane (10%) "cell outer membrane (70%) plasma membrane (10%)" monoatomic ion channel activity (10%) "IPR012910 (12.7%) IPR023996 (12.7%) IPR023997 (12.7%)" "TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" GFGVNNTGLAVFLDFSESLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (12.7%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (12.7%)" "IPR003953 (14.3%) IPR011280 (14.3%) IPR015939 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%)" LLADKELQVDPSQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (45%) GO:0000272 (5%)" "GO:0004553 (35%) GO:0031176 (15%)" "xylan catabolic process (45%) polysaccharide catabolic process (5%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (35%) endo-1,4-beta-xylanase activity (15%)" "IPR001000 (32.3%) IPR017853 (29%) IPR044846 (29%)" "Glycoside hydrolase family 10 domain (32.3%) Glycoside hydrolase superfamily (29%) Glycoside hydrolase family 10 (29%)" LEGLRPGMSLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR032317 (50.9%) IPR011053 (47.2%) IPR039562 (1.9%)" "Unknown (50.9%) Single hybrid motif (47.2%) Unknown (1.9%)" FYALFAPNDNPGGETYLCTADDLEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.6%) "GO:0004553 (33.6%) GO:0030246 (32.8%)" carbohydrate metabolic process (33.6%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.6%) carbohydrate binding (32.8%)" "IPR006710 (13%) IPR051795 (13%) IPR005084 (12.6%)" "Glycoside hydrolase, family 43 (13%) Glycosyl Hydrolase Family 43 (13%) Carbohydrate binding module family 6 (12.6%)" LGLNDPVQGLYGNSTWLAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.1%) IPR012944 (32.1%) IPR033985 (29.5%)" "Tetratricopeptide-like helical domain superfamily (32.1%) RagB/SusD domain (32.1%) SusD-like, N-terminal (29.5%)" LPCSWVMGHLTDAEACTLDADWLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (20%) IPR013783 (20%) IPR017853 (20%)" "Glycoside hydrolase, family 5 (20%) Immunoglobulin-like fold (20%) Glycoside hydrolase superfamily (20%)" MSDKNSFLVFSGTNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (11.1%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (11.1%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (16.7%) IPR000842 (16.7%) IPR005946 (16.7%)" "Phosphoribosyltransferase domain (16.7%) Phosphoribosyl pyrophosphate synthetase, conserved site (16.7%) Ribose-phosphate pyrophosphokinase (16.7%)" MKLENELLSSVLAAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001278 (12.9%) IPR001412 (12.9%) IPR005148 (12.9%)" "Arginine-tRNA ligase (12.9%) Aminoacyl-tRNA synthetase, class I, conserved site (12.9%) Arginyl tRNA synthetase N-terminal domain (12.9%)" MQLDEETEYNGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR031965 (50%)" "Immunoglobulin-like fold (50%) Starch-binding module 26 (50%)" LGKLPLSLPAGVTVNYDETSHVCTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" GVHNSYNSPDSLNQFTWTNLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50%) "GO:0016798 (36.1%) GO:0051060 (13.9%)" carbohydrate metabolic process (50%) "hydrolase activity, acting on glycosyl bonds (36.1%) pullulanase activity (13.9%)" "IPR006047 (14.7%) IPR011840 (14.7%) IPR049117 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (14.7%) Pullulanase, type I (14.7%) Pullulanase, all-beta domain (14.7%)" GSSLVELVSTCNSGWK Pseudomonadati Bacteria Pseudomonadati 1.2.7.3 (100%) 2-oxoglutarate synthase (100%) GO:0044281 (33.3%) "GO:0030976 (33.3%) GO:0016625 (32%) GO:0047553 (1.3%)" small molecule metabolic process (33.3%) "thiamine pyrophosphate binding (33.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (32%) 2-oxoglutarate synthase activity (1.3%)" "IPR011766 (33.3%) IPR029061 (33.3%) IPR051457 (33.3%)" "Thiamine pyrophosphate enzyme, TPP-binding (33.3%) Thiamin diphosphate-binding fold (33.3%) 2-oxoacid:ferredoxin oxidoreductase (33.3%)" LHHSFMVCEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (51.4%) IPR029052 (48.6%)" "Fructose-1,6-bisphosphatase class 3 (51.4%) Metallo-dependent phosphatase-like (48.6%)" ASELLGVDEAER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.7%) GO:0004560 (51.3%) carbohydrate metabolic process (48.7%) alpha-L-fucosidase activity (51.3%) "IPR027414 (17.1%) IPR049053 (17.1%) IPR054363 (17.1%)" "Glycosyl hydrolase family 95, N-terminal domain (17.1%) Alpha fucosidase A-like, C-terminal domain (17.1%) Glycosyl hydrolase family 95, catalytic domain (17.1%)" NNDLALLTLGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.1%) IPR002772 (11.1%) IPR013783 (11.1%)" "Glycoside hydrolase, family 3, N-terminal (11.1%) Glycoside hydrolase family 3 C-terminal domain (11.1%) Immunoglobulin-like fold (11.1%)" QFGLTADATLATR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (30.7%) GO:0009279 (35.2%) GO:0015344 (34.1%) siderophore transmembrane transport (30.7%) cell outer membrane (35.2%) siderophore uptake transmembrane transporter activity (34.1%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" NLLLSTGSAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.5%) GO:0006526 (13.6%) GO:0006221 (13.1%)" GO:0005737 (14.5%) "GO:0004088 (14.5%) GO:0005524 (14.5%) GO:0046872 (13.6%)" "glutamine metabolic process (14.5%) L-arginine biosynthetic process (13.6%) pyrimidine nucleotide biosynthetic process (13.1%)" cytoplasm (14.5%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.5%) ATP binding (14.5%) metal ion binding (13.6%)" "IPR011607 (10.8%) IPR036914 (10.8%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (10.8%) Methylglyoxal synthase-like domain superfamily (10.8%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" NGFFLLNTLFDGEELVNFLPNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (13.9%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (13.9%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" MLGSAEETEFEENLDCPYLVNDTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (20%) GO:0006354 (20%) GO:0031564 (20%)" GO:0005829 (20%) "DNA-templated transcription termination (20%) DNA-templated transcription elongation (20%) transcription antitermination (20%)" cytosol (20%) "IPR001062 (12.5%) IPR005824 (12.5%) IPR006645 (12.5%)" "Transcription antitermination protein, NusG (12.5%) KOW (12.5%) NusG-like, N-terminal (12.5%)" NHLRPDETLFVVDSMTGQDAVNTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20.2%) "GO:0048500 (19.1%) GO:0005786 (1.1%)" "GO:0003924 (20.2%) GO:0005525 (20.2%) GO:0008312 (18%)" SRP-dependent cotranslational protein targeting to membrane (20.2%) "signal recognition particle (19.1%) signal recognition particle, endoplasmic reticulum targeting (1.1%)" "GTPase activity (20.2%) GTP binding (20.2%) 7S RNA binding (18%)" "IPR000897 (11.6%) IPR003593 (11.6%) IPR022941 (11.6%)" "Signal recognition particle, SRP54 subunit, GTPase domain (11.6%) AAA+ ATPase domain (11.6%) Signal recognition particle, SRP54 subunit (11.6%)" VGALLDTTFYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.8%) IPR013486 (12.8%) IPR013693 (12.8%)" "Glycosyltransferase 2-like (12.8%) Sporulation stage II protein D, amidase enhancer LytB (12.8%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.8%)" LLQFDKLDGER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR012547 (37.8%) IPR018631 (37.8%) IPR027417 (24.5%)" "PD-(D/E)XK nuclease superfamily 9 (37.8%) AAA-ATPase-like domain (37.8%) P-loop containing nucleoside triphosphate hydrolase (24.5%)" DNFFMTLR Bacteria Bacteria GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.4%) IPR008969 (48.6%)" "Family of unknown function DUF5686 (51.4%) Carboxypeptidase-like, regulatory domain superfamily (48.6%)" LYGSVYNVFTLTK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12%) IPR008969 (12%) IPR012910 (12%)" "TonB-dependent receptor-like, beta-barrel (12%) Carboxypeptidase-like, regulatory domain superfamily (12%) TonB-dependent receptor, plug domain (12%)" MVEFMGDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (24.3%) GO:0004540 (0.7%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (24.3%) RNA nuclease activity (0.7%)" "IPR001900 (12.8%) IPR022966 (12.8%) IPR050180 (12.8%)" "Ribonuclease II/R (12.8%) Ribonuclease II/R, conserved site (12.8%) RNR Ribonuclease (12.8%)" LTDNLNSQFFEAANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) IPR029492 (100%) Domain of unknown function DUF4435 (100%) GYQQTYQGFNPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.5.1.28 (100%) N-acetylmuramoyl-L-alanine amidase (100%) GO:0009253 (33.3%) GO:0030288 (33.3%) GO:0008745 (33.3%) peptidoglycan catabolic process (33.3%) outer membrane-bounded periplasmic space (33.3%) N-acetylmuramoyl-L-alanine amidase activity (33.3%) "IPR002508 (50%) IPR050695 (50%)" "N-acetylmuramoyl-L-alanine amidase, catalytic domain (50%) N-acetylmuramoyl-L-alanine amidase 3 (50%)" ALQNLLNLESDDQVNAFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.8%) IPR005743 (12.8%) IPR006691 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA gyrase, subunit A (12.8%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%)" YEGLSDNMELELAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044341 (33.3%) GO:0005886 (33.3%) GO:0005436 (33.3%) sodium-dependent phosphate transport (33.3%) plasma membrane (33.3%) sodium:phosphate symporter activity (33.3%) "IPR003841 (33%) IPR038078 (32.6%) IPR026022 (18.8%)" "Sodium-dependent phosphate transport protein (33%) PhoU-like domain superfamily (32.6%) PhoU domain (18.8%)" VKDALVDWFR Pseudomonadati Bacteria Pseudomonadati "2.1.1.173 (50%) 2.1.1.- (25%) 2.1.1.264 (25%)" "23S rRNA (guanine(2445)-N(2))-methyltransferase (50%) Methyltransferases (25%) 23S rRNA (guanine(2069)-N(7))-methyltransferase (25%)" GO:0005737 (0.7%) "GO:0003723 (33.1%) GO:0070043 (33.1%) GO:0008990 (32.4%)" cytoplasm (0.7%) "RNA binding (33.1%) rRNA (guanine-N7-)-methyltransferase activity (33.1%) rRNA (guanine-N2-)-methyltransferase activity (32.4%)" "IPR000241 (16.8%) IPR004114 (16.8%) IPR054170 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) THUMP domain (16.8%) RlmL, ferredoxin-like domain (16.8%)" LNVTVAPNEETDAALEAFADYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004822 (14.3%)" isoleucyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) isoleucine-tRNA ligase activity (14.3%)" "IPR002300 (12.5%) IPR002301 (12.5%) IPR009008 (12.5%)" "Aminoacyl-tRNA synthetase, class Ia (12.5%) Isoleucine-tRNA ligase (12.5%) Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain (12.5%)" EALCAAMK Bacteria Bacteria "1.2.1.- (98.6%) 1.2.1.12 (1.4%)" "With NAD(+) or NADP(+) as acceptor (98.6%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (1.4%)" "GO:0006006 (18.3%) GO:0006096 (1.8%)" GO:0005737 (0.8%) "GO:0051287 (29.9%) GO:0016620 (19%) GO:0050661 (18.3%)" "glucose metabolic process (18.3%) glycolytic process (1.8%)" cytoplasm (0.8%) "NAD binding (29.9%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (19%) NADP binding (18.3%)" "IPR020829 (18.1%) IPR020831 (18.1%) IPR020830 (17.9%)" "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (18.1%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (18.1%) Glyceraldehyde 3-phosphate dehydrogenase, active site (17.9%)" TDADAESALVAAYESFMCNVMGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TFFETLGYENSKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR008979 (25%) IPR013830 (25%) IPR036514 (25%)" "Galactose-binding-like domain superfamily (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" CVDECPTGALVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.-.-.- (100%) Translocases (100%) GO:0022900 (19.7%) GO:0005886 (19.7%) "GO:0046872 (20.5%) GO:0009055 (19.7%) GO:0051539 (19.7%)" electron transport chain (19.7%) plasma membrane (19.7%) "metal ion binding (20.5%) electron transfer activity (19.7%) 4 iron, 4 sulfur cluster binding (19.7%)" "IPR017896 (20.5%) IPR017900 (20.5%) IPR007202 (19.7%)" "4Fe-4S ferredoxin-type, iron-sulphur binding domain (20.5%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (20.5%) 4Fe-4S domain (19.7%)" QYGGVPLK root "GO:0006310 (1.3%) GO:0015074 (1.3%)" GO:0009279 (96.2%) GO:0003677 (1.3%) "DNA recombination (1.3%) DNA integration (1.3%)" cell outer membrane (96.2%) DNA binding (1.3%) "IPR011990 (32.1%) IPR033985 (32.1%) IPR012944 (31.3%)" "Tetratricopeptide-like helical domain superfamily (32.1%) SusD-like, N-terminal (32.1%) RagB/SusD domain (31.3%)" LFGTSAFNGALNLVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" GFLQTPFNTPWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.8%) GO:0016787 (48.2%)" "carbohydrate binding (51.8%) hydrolase activity (48.2%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" GLELDLDK root "6.3.5.3 (78%) 2.7.7.7 (8.8%) 4.2.1.2 (8.7%)" "phosphoribosylformylglycinamidine synthase (78%) DNA-directed DNA polymerase (8.8%) fumarate hydratase (8.7%)" "GO:0006189 (9.1%) GO:0006164 (5.9%) GO:0006099 (2%)" "GO:0005737 (16%) GO:0005829 (1.2%) GO:0032993 (0.7%)" "GO:0004642 (15%) GO:0005524 (9.7%) GO:0000287 (9.1%)" "'de novo' IMP biosynthetic process (9.1%) purine nucleotide biosynthetic process (5.9%) tricarboxylic acid cycle (2%)" "cytoplasm (16%) cytosol (1.2%) protein-DNA complex (0.7%)" "phosphoribosylformylglycinamidine synthase activity (15%) ATP binding (9.7%) magnesium ion binding (9.1%)" "IPR010918 (10.8%) IPR036676 (10.8%) IPR036921 (10.8%)" "PurM-like, C-terminal domain (10.8%) PurM-like, C-terminal domain superfamily (10.8%) PurM-like, N-terminal domain superfamily (10.8%)" GVVYLSLADNMLYQSGSYEVNSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR006665 (34%) IPR050330 (34%) IPR036737 (31.9%)" "OmpA-like domain (34%) Bacterial Outer Membrane Structural/Functional (34%) OmpA-like domain superfamily (31.9%)" LLSYNDAK root "GO:0006508 (11.1%) GO:0006777 (11.1%)" "GO:0005737 (11.1%) GO:0005886 (11.1%)" "GO:0004222 (11.1%) GO:0004713 (11.1%) GO:0016491 (11.1%)" "proteolysis (11.1%) Mo-molybdopterin cofactor biosynthetic process (11.1%)" "cytoplasm (11.1%) plasma membrane (11.1%)" "metalloendopeptidase activity (11.1%) protein tyrosine kinase activity (11.1%) oxidoreductase activity (11.1%)" "IPR015943 (38.7%) IPR000674 (3.2%) IPR001453 (3.2%)" "WD40/YVTN repeat-like-containing domain superfamily (38.7%) Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead (3.2%) MoaB/Mog domain (3.2%)" GATVLDFAYYLHSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015969 (43.7%) GO:0005886 (43.7%) GO:0016787 (12.7%) guanosine tetraphosphate metabolic process (43.7%) plasma membrane (43.7%) hydrolase activity (12.7%) "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" DDATGKWETTTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35%) IPR012944 (35%) IPR033985 (30%)" "Tetratricopeptide-like helical domain superfamily (35%) RagB/SusD domain (35%) SusD-like, N-terminal (30%)" AKGDVMQLDLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QLLEWLAQECENAANDLDERK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.9%) IPR033985 (31.8%) IPR012944 (28.2%)" "Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (31.8%) RagB/SusD domain (28.2%)" QSEHFFVFWSPEFGDDPNAESVDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (25%) IPR024361 (25%) IPR032339 (25%)" "Immunoglobulin-like fold (25%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (25%) Domain of unknown function DUF4859 (25%)" SNMFSFK root GO:0015074 (6.7%) "GO:0009279 (66.7%) GO:0016020 (6.7%)" "GO:0003676 (6.7%) GO:0005524 (6.7%) GO:0016787 (6.7%)" DNA integration (6.7%) "cell outer membrane (66.7%) membrane (6.7%)" "nucleic acid binding (6.7%) ATP binding (6.7%) hydrolase activity (6.7%)" "IPR000531 (9.9%) IPR008969 (9.9%) IPR012910 (9.9%)" "TonB-dependent receptor-like, beta-barrel (9.9%) Carboxypeptidase-like, regulatory domain superfamily (9.9%) TonB-dependent receptor, plug domain (9.9%)" ELAGSWEVKDGGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" VFNLLLQVLDEGR root 3.4.21.92 (100%) endopeptidase Clp (100%) "GO:0034605 (18.8%) GO:0006508 (10.6%) GO:0042026 (3.2%)" "GO:0005737 (18.5%) GO:0005829 (0.3%)" "GO:0005524 (18.8%) GO:0016887 (18.8%) GO:0008233 (10.4%)" "cellular response to heat (18.8%) proteolysis (10.6%) protein refolding (3.2%)" "cytoplasm (18.5%) cytosol (0.3%)" "ATP binding (18.8%) ATP hydrolysis activity (18.8%) peptidase activity (10.4%)" "IPR003959 (9.1%) IPR050130 (9.1%) IPR003593 (9%)" "ATPase, AAA-type, core (9.1%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (9.1%) AAA+ ATPase domain (9%)" KGYYHNVNNLDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" GNGTHAYSAYDVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.7%) IPR011990 (32.1%) IPR033985 (32.1%)" "RagB/SusD domain (35.7%) Tetratricopeptide-like helical domain superfamily (32.1%) SusD-like, N-terminal (32.1%)" VTAVPFYANSSEQQLQYMLNDAQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (33.3%) IPR020845 (33.3%) IPR042099 (33.3%)" "AMP-dependent synthetase/ligase domain (33.3%) AMP-binding, conserved site (33.3%) ANL, N-terminal domain (33.3%)" ALQGMLGR root "2.3.1.39 (92.5%) 4.1.1.36 (2.2%) 6.3.2.5 (2.2%)" "[acyl-carrier-protein] S-malonyltransferase (92.5%) phosphopantothenoylcysteine decarboxylase (2.2%) phosphopantothenate--cysteine ligase (CTP) (2.2%)" "GO:0006633 (28.8%) GO:0032259 (0.7%) GO:0000103 (0.4%)" "GO:0005829 (28.8%) GO:0005737 (0.7%) GO:0005576 (0.4%)" "GO:0004314 (29.6%) GO:0003676 (0.7%) GO:0008168 (0.7%)" "fatty acid biosynthetic process (28.8%) methylation (0.7%) sulfate assimilation (0.4%)" "cytosol (28.8%) cytoplasm (0.7%) extracellular region (0.4%)" "[acyl-carrier-protein] S-malonyltransferase activity (29.6%) nucleic acid binding (0.7%) methyltransferase activity (0.7%)" "IPR004410 (13.5%) IPR014043 (13.5%) IPR001227 (13.3%)" "Malonyl CoA-acyl carrier protein transacylase, FabD-type (13.5%) Acyl transferase domain (13.5%) Acyl transferase domain superfamily (13.3%)" LLGKPYSSDYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) ELVELDSK root "2.7.11.1 (63.6%) 2.2.1.2 (9.1%) 3.4.19.12 (9.1%)" "non-specific serine/threonine protein kinase (63.6%) transaldolase (9.1%) ubiquitinyl hydrolase 1 (9.1%)" "GO:0006260 (2.8%) GO:0006793 (0.9%) GO:0046716 (0.9%)" "GO:0005886 (26.1%) GO:0005737 (2.8%) GO:0016020 (1.4%)" "GO:0005524 (19%) GO:0016887 (11.4%) GO:0004674 (3.8%)" "DNA replication (2.8%) phosphorus metabolic process (0.9%) muscle cell cellular homeostasis (0.9%)" "plasma membrane (26.1%) cytoplasm (2.8%) membrane (1.4%)" "ATP binding (19%) ATP hydrolysis activity (11.4%) protein serine/threonine kinase activity (3.8%)" "IPR006160 (16.3%) IPR006161 (15.8%) IPR027417 (8.2%)" "Short chain fatty acid transporter AtoE (16.3%) Conserved hypothetical protein CHP00336 (15.8%) P-loop containing nucleoside triphosphate hydrolase (8.2%)" APFKETFDDSLPVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" DLAQELSGSVDNLEFDPNRLETLNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006281 (20%) GO:0006310 (20%) GO:0009432 (20%)" GO:0043590 (20%) GO:0005524 (20%) "DNA repair (20%) DNA recombination (20%) SOS response (20%)" bacterial nucleoid (20%) ATP binding (20%) "IPR003395 (33.8%) IPR004604 (33.8%) IPR027417 (32.5%)" "RecF/RecN/SMC, N-terminal (33.8%) DNA recombination/repair protein RecN (33.8%) P-loop containing nucleoside triphosphate hydrolase (32.5%)" LSPEGNDRFLQSESLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" HEVSEEASYLYAPLAHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015969 (40.9%) GO:0005886 (43.9%) "GO:0016787 (12.1%) GO:0016301 (3%)" guanosine tetraphosphate metabolic process (40.9%) plasma membrane (43.9%) "hydrolase activity (12.1%) kinase activity (3%)" "IPR043519 (10.3%) IPR002912 (10%) IPR004095 (10%)" "Nucleotidyltransferase superfamily (10.3%) ACT domain (10%) TGS (10%)" LVNNMHEAYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR003741 (34.4%) IPR024185 (32.8%) IPR037171 (32.8%)" "LUD domain (34.4%) 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily (32.8%) NagB/RpiA transferase-like (32.8%)" HNNWSLATDTGLLLHGPGKTPEDNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.5%) GO:0004356 (51.5%) glutamine biosynthetic process (48.5%) glutamine synthetase activity (51.5%) "IPR008146 (14.7%) IPR027303 (14.7%) IPR040577 (14.7%)" "Glutamine synthetase, catalytic domain (14.7%) Glutamine synthetase, glycine-rich site (14.7%) Glutamine synthetase, C-terminal (14.7%)" EACGLGLK root 2.1.1.225 (100%) tRNA:m(4)X modification enzyme (100%) "GO:0006412 (24.7%) GO:0006633 (0.1%) GO:0030488 (0.1%)" "GO:0022625 (24.7%) GO:0005737 (0.1%) GO:0005840 (0.1%)" "GO:0003729 (24.7%) GO:0003735 (24.7%) GO:0004315 (0.1%)" "translation (24.7%) fatty acid biosynthetic process (0.1%) tRNA methylation (0.1%)" "cytosolic large ribosomal subunit (24.7%) cytoplasm (0.1%) ribosome (0.1%)" "mRNA binding (24.7%) structural constituent of ribosome (24.7%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (0.1%)" "IPR000206 (19.8%) IPR013823 (19.8%) IPR014719 (19.8%)" "Large ribosomal subunit protein bL12 (19.8%) Large ribosomal subunit protein bL12, C-terminal (19.8%) Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like (19.8%)" KFLESHEEQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) LGMELQR root "2.7.10.2 (55.9%) 7.6.2.2 (10.3%) 7.6.2.3 (10.3%)" "non-specific protein-tyrosine kinase (55.9%) ABC-type xenobiotic transporter (10.3%) ABC-type glutathione-S-conjugate transporter (10.3%)" "GO:0015074 (3.5%) GO:0006310 (1.4%) GO:0006281 (0.9%)" "GO:0005886 (8.9%) GO:0016020 (3.3%) GO:0005634 (2.4%)" "GO:0005524 (11.2%) GO:0016887 (5%) GO:0140359 (5%)" "DNA integration (3.5%) DNA recombination (1.4%) DNA repair (0.9%)" "plasma membrane (8.9%) membrane (3.3%) nucleus (2.4%)" "ATP binding (11.2%) ATP hydrolysis activity (5%) ABC-type transporter activity (5%)" "IPR027417 (5.9%) IPR013103 (5%) IPR043502 (3.2%)" "P-loop containing nucleoside triphosphate hydrolase (5.9%) Reverse transcriptase, RNA-dependent DNA polymerase (5%) DNA/RNA polymerase superfamily (3.2%)" LLELYHAVDALPGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0003824 (33.3%) GO:0051539 (33.3%) GO:0005506 (32.6%)" "catalytic activity (33.3%) 4 iron, 4 sulfur cluster binding (33.3%) iron ion binding (32.6%)" "IPR007197 (14.5%) IPR013704 (14.5%) IPR020612 (14.5%)" "Radical SAM (14.5%) UPF0313, N-terminal (14.5%) Methylthiotransferase, conserved site (14.5%)" LGNESVVADSTEHKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR007421 (34%) IPR038461 (34%) IPR038475 (32%)" "Schlafen, AlbA_2 domain (34%) Schlafen, AlbA_2 domain superfamily (34%) RecG, C-terminal domain superfamily (32%)" GEYHYSQLMNNHYQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (51.9%) GO:0016787 (48.1%)" "carbohydrate binding (51.9%) hydrolase activity (48.1%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" LTDYAFDALPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (52.1%) IPR008969 (47.9%)" "Family of unknown function DUF5686 (52.1%) Carboxypeptidase-like, regulatory domain superfamily (47.9%)" EKSYELWLEGCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (31.8%) IPR012944 (31.8%) IPR033985 (29.4%)" "Tetratricopeptide-like helical domain superfamily (31.8%) RagB/SusD domain (31.8%) SusD-like, N-terminal (29.4%)" FWNLAEVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.6.2.4 (96.8%) 3.6.4.12 (3.2%)" "DNA 3'-5' helicase (96.8%) DNA helicase (3.2%)" "GO:0006281 (10%) GO:0006310 (10%)" "GO:0005737 (10%) GO:0030894 (10%) GO:0043590 (10%)" "GO:0003676 (10%) GO:0005524 (10%) GO:0009378 (10%)" "DNA repair (10%) DNA recombination (10%)" "cytoplasm (10%) replisome (10%) bacterial nucleoid (10%)" "nucleic acid binding (10%) ATP binding (10%) four-way junction helicase activity (10%)" "IPR001650 (14.3%) IPR004589 (14.3%) IPR011545 (14.3%)" "Helicase, C-terminal domain-like (14.3%) DNA helicase, ATP-dependent, RecQ type (14.3%) DEAD/DEAH-box helicase domain (14.3%)" WGCEGELNCWER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (10.4%) GO:0000272 (8.3%)" GO:0009341 (10.4%) "GO:0016985 (60.4%) GO:0004565 (10.4%)" "carbohydrate metabolic process (10.4%) polysaccharide catabolic process (8.3%)" beta-galactosidase complex (10.4%) "mannan endo-1,4-beta-mannosidase activity (60.4%) beta-galactosidase activity (10.4%)" "IPR045053 (44.6%) IPR017853 (41.5%) IPR013529 (7.7%)" "Mannan endo-1,4-beta-mannosidase-like (44.6%) Glycoside hydrolase superfamily (41.5%) Glycoside hydrolase, family 42, N-terminal (7.7%)" EVHNLTNSGYSDSNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.3%) IPR011659 (14.3%) IPR012393 (14.3%)" "Tail specific protease (14.3%) WD40-like beta-propeller (14.3%) Tricorn protease (14.3%)" TPNNTPSWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (30.6%) "GO:0030170 (34.7%) GO:0010285 (30.6%) GO:0008483 (4.1%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (30.6%) "pyridoxal phosphate binding (34.7%) L,L-diaminopimelate aminotransferase activity (30.6%) transaminase activity (4.1%)" "IPR004839 (22.1%) IPR019942 (22.1%) IPR015422 (19.5%)" "Aminotransferase, class I/classII, large domain (22.1%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (22.1%) Pyridoxal phosphate-dependent transferase, small domain (19.5%)" LVTYPLDK root 6.5.1.2 (100%) DNA ligase (NAD(+)) (100%) "GO:0005975 (12.5%) GO:0009401 (8.3%) GO:0006260 (4.2%)" GO:0005886 (12.5%) "GO:0004553 (12.5%) GO:0015577 (8.3%) GO:0071949 (8.3%)" "carbohydrate metabolic process (12.5%) phosphoenolpyruvate-dependent sugar phosphotransferase system (8.3%) DNA replication (4.2%)" plasma membrane (12.5%) "hydrolase activity, hydrolyzing O-glycosyl compounds (12.5%) galactitol transmembrane transporter activity (8.3%) FAD binding (8.3%)" "IPR015943 (18.5%) IPR006102 (4.6%) IPR006103 (4.6%)" "WD40/YVTN repeat-like-containing domain superfamily (18.5%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (4.6%) Glycoside hydrolase family 2, catalytic domain (4.6%)" NYLMEVAAPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (35.7%) IPR031107 (35.7%) IPR008978 (28.6%)" "Alpha crystallin/Hsp20 domain (35.7%) Small heat shock protein (35.7%) HSP20-like chaperone (28.6%)" KLLLFDDLLASGNSVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (51.4%) IPR029057 (48.6%)" "Phosphoribosyltransferase domain (51.4%) Phosphoribosyltransferase-like (48.6%)" ALTVAELAK root 2.3.1.191 (100%) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (100%) GO:0009245 (4%) "GO:0005829 (20%) GO:0016020 (4%)" "GO:0003743 (20%) GO:0003924 (20%) GO:0005525 (20%)" lipid A biosynthetic process (4%) "cytosol (20%) membrane (4%)" "translation initiation factor activity (20%) GTPase activity (20%) GTP binding (20%)" "IPR019707 (15.5%) IPR036388 (15.5%) IPR000178 (4.9%)" "MJ1608-like (15.5%) Winged helix-like DNA-binding domain superfamily (15.5%) Translation initiation factor IF-2, bacterial-like (4.9%)" LGNDVLFK root "2.7.1.16 (22.2%) 2.4.-.- (11.1%) 2.7.1.- (11.1%)" "ribulokinase (22.2%) Glycosyltransferases (11.1%) Phosphotransferases with an alcohol group as acceptor (11.1%)" "GO:0005975 (40.3%) GO:0055070 (1.5%) GO:0060003 (1.5%)" GO:0005886 (1.5%) "GO:0016301 (40.3%) GO:0005524 (3%) GO:0008741 (3%)" "carbohydrate metabolic process (40.3%) copper ion homeostasis (1.5%) copper ion export (1.5%)" plasma membrane (1.5%) "kinase activity (40.3%) ATP binding (3%) ribulokinase activity (3%)" "IPR018484 (20.6%) IPR018485 (20.6%) IPR043129 (20.6%)" "Carbohydrate kinase FGGY, N-terminal (20.6%) Carbohydrate kinase FGGY, C-terminal (20.6%) ATPase, nucleotide binding domain (20.6%)" ALELLEK root "6.1.1.22 (9.9%) 7.4.2.9 (7.6%) 5.6.2.4 (6.4%)" "asparagine--tRNA ligase (9.9%) ABC-type dipeptide transporter (7.6%) DNA 3'-5' helicase (6.4%)" "GO:0015031 (2.7%) GO:0006887 (2.3%) GO:0006002 (1.1%)" "GO:0005886 (2.9%) GO:0005737 (2.8%) GO:0005829 (2.5%)" "GO:0005524 (6.2%) GO:0016887 (2%) GO:0003677 (1.7%)" "protein transport (2.7%) exocytosis (2.3%) fructose 6-phosphate metabolic process (1.1%)" "plasma membrane (2.9%) cytoplasm (2.8%) cytosol (2.5%)" "ATP binding (6.2%) ATP hydrolysis activity (2%) DNA binding (1.7%)" "IPR027417 (2.7%) IPR036892 (2%) IPR004172 (2%)" "P-loop containing nucleoside triphosphate hydrolase (2.7%) L27 domain superfamily (2%) L27 domain (2%)" DMLDAWSPSNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" HQLFEADGAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (19.6%) GO:0015949 (19.6%)" GO:0005829 (19.6%) "GO:0005524 (19.6%) GO:0036431 (19.6%) GO:0036430 (2%)" "pyrimidine nucleotide metabolic process (19.6%) nucleobase-containing small molecule interconversion (19.6%)" cytosol (19.6%) "ATP binding (19.6%) dCMP kinase activity (19.6%) CMP kinase activity (2%)" "IPR003136 (33.3%) IPR011994 (33.3%) IPR027417 (33.3%)" "Cytidylate kinase (33.3%) Cytidylate kinase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" AFVVFQPGDFAGDLSCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) GO:0045493 (50%) "GO:0004553 (42.9%) GO:0031176 (7.1%)" xylan catabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (42.9%) endo-1,4-beta-xylanase activity (7.1%)" "IPR001000 (35%) IPR044846 (35%) IPR017853 (30%)" "Glycoside hydrolase family 10 domain (35%) Glycoside hydrolase family 10 (35%) Glycoside hydrolase superfamily (30%)" SLLVSMLAHYYDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005524 (100%) ATP binding (100%) "IPR018631 (36%) IPR012547 (32%) IPR027417 (32%)" "AAA-ATPase-like domain (36%) PD-(D/E)XK nuclease superfamily 9 (32%) P-loop containing nucleoside triphosphate hydrolase (32%)" EVSNLVSR root 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006313 (2.7%) GO:0006220 (1.4%) GO:0006412 (1.4%)" "GO:0009279 (31.1%) GO:0016020 (6.8%) GO:0005737 (1.4%)" "GO:0005524 (4.1%) GO:0003677 (2.7%) GO:0004497 (2.7%)" "DNA transposition (2.7%) pyrimidine nucleotide metabolic process (1.4%) translation (1.4%)" "cell outer membrane (31.1%) membrane (6.8%) cytoplasm (1.4%)" "ATP binding (4.1%) DNA binding (2.7%) monooxygenase activity (2.7%)" "IPR036942 (11%) IPR023996 (10.5%) IPR039426 (10.5%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (11%) TonB-dependent outer membrane protein, SusC/RagA (10.5%) TonB-dependent receptor-like (10.5%)" LETLSGLK root "5.1.1.7 (77.1%) 6.3.5.5 (4.3%) 6.3.4.16 (2.9%)" "diaminopimelate epimerase (77.1%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (4.3%) carbamoyl-phosphate synthase (ammonia) (2.9%)" "GO:0009089 (16.2%) GO:0006526 (0.7%) GO:0006541 (0.7%)" "GO:0005829 (15.8%) GO:0016020 (2.6%) GO:0005737 (1.9%)" "GO:0008837 (16.2%) GO:0046872 (4.1%) GO:0005524 (3.7%)" "lysine biosynthetic process via diaminopimelate (16.2%) L-arginine biosynthetic process (0.7%) glutamine metabolic process (0.7%)" "cytosol (15.8%) membrane (2.6%) cytoplasm (1.9%)" "diaminopimelate epimerase activity (16.2%) metal ion binding (4.1%) ATP binding (3.7%)" "IPR001653 (13.6%) IPR018510 (12.7%) IPR023214 (1.6%)" "Diaminopimelate epimerase, DapF (13.6%) Diaminopimelate epimerase, active site (12.7%) HAD superfamily (1.6%)" SLAVFQR root "2.-.-.- (24%) 1.14.13.84 (20%) 2.6.1.- (16%)" "Transferases (24%) 4-hydroxyacetophenone monooxygenase (20%) Transaminases (16%)" "GO:0006089 (13.9%) GO:0055085 (2.5%) GO:0006506 (1%)" "GO:0016020 (9.7%) GO:0005886 (1.3%) GO:0005789 (1%)" "GO:0046872 (14.4%) GO:0051539 (13.9%) GO:0004499 (3%)" "lactate metabolic process (13.9%) transmembrane transport (2.5%) GPI anchor biosynthetic process (1%)" "membrane (9.7%) plasma membrane (1.3%) endoplasmic reticulum membrane (1%)" "metal ion binding (14.4%) 4 iron, 4 sulfur cluster binding (13.9%) N,N-dimethylaniline monooxygenase activity (3%)" "IPR003741 (7.6%) IPR004452 (7.6%) IPR017896 (7.6%)" "LUD domain (7.6%) L-lactate oxidation iron-sulfur protein LutB/LldF (7.6%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (7.6%)" TFLQFHYDLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR039968 (50.9%) IPR016181 (49.1%)" "Bacterial ceramide synthase-like (50.9%) Acyl-CoA N-acyltransferase (49.1%)" EMNLQLCEPLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.9%) "GO:0003921 (32.9%) GO:0005524 (32.9%) GO:0016740 (1.2%)" cytosol (32.9%) "GMP synthase activity (32.9%) ATP binding (32.9%) transferase activity (1.2%)" "IPR001674 (12.9%) IPR025777 (12.9%) IPR004739 (12.4%)" "GMP synthase, C-terminal (12.9%) GMP synthetase ATP pyrophosphatase domain (12.9%) GMP synthase, glutamine amidotransferase (12.4%)" SDVERDWEDLMPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.1%) IPR010918 (11.1%) IPR029062 (11.1%)" "Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%) Class I glutamine amidotransferase-like (11.1%)" DGFSFSTSSTTEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (11.5%) GO:0000272 (7.7%)" GO:0009341 (11.5%) "GO:0016985 (57.7%) GO:0004565 (11.5%)" "carbohydrate metabolic process (11.5%) polysaccharide catabolic process (7.7%)" beta-galactosidase complex (11.5%) "mannan endo-1,4-beta-mannosidase activity (57.7%) beta-galactosidase activity (11.5%)" "IPR045053 (44.1%) IPR017853 (41.2%) IPR013529 (8.8%)" "Mannan endo-1,4-beta-mannosidase-like (44.1%) Glycoside hydrolase superfamily (41.2%) Glycoside hydrolase, family 42, N-terminal (8.8%)" GNMWQSEVNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" NLPQEVAVEHLLALLDSDKQ Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.9%) GO:0019288 (18.9%)" "GO:0046429 (18.9%) GO:0051539 (18.9%) GO:0005506 (17.8%)" "terpenoid biosynthetic process (18.9%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.9%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.9%) 4 iron, 4 sulfur cluster binding (18.9%) iron ion binding (17.8%)" "IPR004588 (26.1%) IPR011005 (24.6%) IPR017178 (24.6%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26.1%) Dihydropteroate synthase-like superfamily (24.6%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.6%)" VMGLTVPLVTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LAAEGNLVQPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005507 (34%) GO:0016787 (34%) GO:0016740 (23.3%)" "copper ion binding (34%) hydrolase activity (34%) transferase activity (23.3%)" "IPR003730 (34.7%) IPR011324 (32.7%) IPR038371 (32.7%)" "Multi-copper polyphenol oxidoreductase (34.7%) Cytotoxic necrotizing factor-like, catalytic (32.7%) Multi-copper polyphenol oxidoreductase superfamily (32.7%)" EKDGVPAVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0002181 (20%) GO:0015934 (20%) "GO:0003735 (20%) GO:0016740 (20%) GO:0019843 (19.8%)" cytoplasmic translation (20%) large ribosomal subunit (20%) "structural constituent of ribosome (20%) transferase activity (20%) rRNA binding (19.8%)" "IPR002171 (11.1%) IPR005880 (11.1%) IPR008991 (11.1%)" "Large ribosomal subunit protein uL2 (11.1%) Large ribosomal subunit protein uL2, bacteria/organella (11.1%) Translation protein SH3-like domain superfamily (11.1%)" YVYLAGAGLSGDVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.4%) "GO:0004553 (49.4%) GO:0016787 (1.2%)" carbohydrate metabolic process (49.4%) "hydrolase activity, hydrolyzing O-glycosyl compounds (49.4%) hydrolase activity (1.2%)" "IPR041542 (17.1%) IPR051795 (17.1%) IPR006710 (16.7%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (17.1%) Glycosyl Hydrolase Family 43 (17.1%) Glycoside hydrolase, family 43 (16.7%)" MAQELPEWEDLREHASELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (32%) GO:0051536 (1.3%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (32%) iron-sulfur cluster binding (1.3%)" "IPR003741 (14.5%) IPR004452 (14.5%) IPR017896 (14.5%)" "LUD domain (14.5%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.5%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.5%)" LAELYVNK root 2.3.2.26 (100%) HECT-type E3 ubiquitin transferase (100%) "GO:0006383 (9.7%) GO:0000209 (3.2%) GO:0006270 (3.2%)" "GO:0000127 (9.7%) GO:0016020 (9.7%) GO:0005634 (6.5%)" "GO:0003682 (3.2%) GO:0004175 (3.2%) GO:0005524 (3.2%)" "transcription by RNA polymerase III (9.7%) protein polyubiquitination (3.2%) DNA replication initiation (3.2%)" "transcription factor TFIIIC complex (9.7%) membrane (9.7%) nucleus (6.5%)" "chromatin binding (3.2%) endopeptidase activity (3.2%) ATP binding (3.2%)" "IPR019734 (28.4%) IPR011990 (26.9%) IPR039340 (4.5%)" "Tetratricopeptide repeat (28.4%) Tetratricopeptide-like helical domain superfamily (26.9%) Transcription factor Tfc4/TFIIIC-102/Sfc4 (4.5%)" DYELVEK root "2.7.4.22 (14%) 4.1.2.4 (10.5%) 1.4.1.2 (7%)" "UMP kinase (14%) deoxyribose-phosphate aldolase (10.5%) glutamate dehydrogenase (7%)" "GO:0030866 (13.2%) GO:0045214 (13.1%) GO:0055003 (13.1%)" "GO:0005737 (14%) GO:0005856 (13.5%) GO:0016020 (1%)" "GO:0051015 (13.3%) GO:0005524 (1%) GO:0046872 (0.8%)" "cortical actin cytoskeleton organization (13.2%) sarcomere organization (13.1%) cardiac myofibril assembly (13.1%)" "cytoplasm (14%) cytoskeleton (13.5%) membrane (1%)" "actin filament binding (13.3%) ATP binding (1%) metal ion binding (0.8%)" "IPR015425 (10.8%) IPR042201 (10.8%) IPR014767 (10.1%)" "Formin, FH2 domain (10.8%) Formin, FH2 domain superfamily (10.8%) Diaphanous autoregulatory domain (10.1%)" VAVDLVSLK root 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.1%) "GO:0046556 (49.1%) GO:0008270 (1.8%)" L-arabinose metabolic process (49.1%) "alpha-L-arabinofuranosidase activity (49.1%) zinc ion binding (1.8%)" "IPR010720 (16.8%) IPR051563 (16.8%) IPR055133 (16.8%)" "Alpha-L-arabinofuranosidase, C-terminal (16.8%) Glycosyl Hydrolase Family 51 (16.8%) Arabinosidase BT_3657-like, N-terminal (16.8%)" LTFANDGTCTVSSETEGVTATGTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" LVEDWAR root "3.1.21.3 (27.3%) 2.4.2.4 (13.6%) 3.1.3.106 (9.1%)" "type I site-specific deoxyribonuclease (27.3%) thymidine phosphorylase (13.6%) 2-lysophosphatidate phosphatase (9.1%)" "GO:0006950 (5.9%) GO:0006825 (2.3%) GO:0009307 (1.6%)" "GO:0016020 (14.1%) GO:0005886 (3.1%) GO:0005829 (2.3%)" "GO:0004467 (13.3%) GO:0003700 (5.9%) GO:0016740 (4.7%)" "response to stress (5.9%) copper ion transport (2.3%) DNA restriction-modification system (1.6%)" "membrane (14.1%) plasma membrane (3.1%) cytosol (2.3%)" "long-chain fatty acid-CoA ligase activity (13.3%) DNA-binding transcription factor activity (5.9%) transferase activity (4.7%)" "IPR000873 (6.4%) IPR020845 (6.4%) IPR042099 (6.2%)" "AMP-dependent synthetase/ligase domain (6.4%) AMP-binding, conserved site (6.4%) ANL, N-terminal domain (6.2%)" LYVTYHTQGNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) LGYSSLSYNGQFGVNTVYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VLDDSGAPLVGATVQLLHSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.7%) IPR008969 (16.7%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (16.7%) Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%)" LEMLVDAGSFEEYDMFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.-.-.- (100%) Ligases (100%) "GO:0015977 (22.1%) GO:0006633 (8.7%)" GO:0009317 (22.1%) "GO:0004658 (23.1%) GO:0003989 (22.1%) GO:0016740 (1.9%)" "carbon fixation (22.1%) fatty acid biosynthetic process (8.7%)" acetyl-CoA carboxylase complex (22.1%) "propionyl-CoA carboxylase activity (23.1%) acetyl-CoA carboxylase activity (22.1%) transferase activity (1.9%)" "IPR011762 (18.9%) IPR011763 (18.9%) IPR034733 (18.9%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.9%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.9%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.9%)" LVDLQNELFMCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.1 (100%) pantoate--beta-alanine ligase (AMP-forming) (100%) GO:0015940 (25%) GO:0005829 (25%) "GO:0004592 (25%) GO:0005524 (25%)" pantothenate biosynthetic process (25%) cytosol (25%) "pantoate-beta-alanine ligase activity (25%) ATP binding (25%)" "IPR003721 (34.1%) IPR014729 (34.1%) IPR042176 (31.8%)" "Pantoate-beta-alanine ligase (34.1%) Rossmann-like alpha/beta/alpha sandwich fold (34.1%) Pantoate-beta-alanine ligase, C-terminal domain (31.8%)" AASNLAQMNLDDTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.3%) "GO:0009279 (20.3%) GO:1990281 (20.3%)" "GO:0015288 (20.3%) GO:0015562 (20.3%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.3%) efflux pump complex (20.3%)" "porin activity (20.3%) efflux transmembrane transporter activity (20.3%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" MLLSSQELSSQDQLLEALHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006526 (14.3%) GO:0051259 (14.3%) GO:1900079 (14.3%)" GO:0005737 (14.3%) "GO:0003677 (14.3%) GO:0003700 (14.3%) GO:0034618 (14.3%)" "L-arginine biosynthetic process (14.3%) protein complex oligomerization (14.3%) regulation of arginine biosynthetic process (14.3%)" cytoplasm (14.3%) "DNA binding (14.3%) DNA-binding transcription factor activity (14.3%) arginine binding (14.3%)" "IPR001669 (16.7%) IPR020899 (16.7%) IPR020900 (16.7%)" "Arginine repressor (16.7%) Arginine repressor, C-terminal (16.7%) Arginine repressor, DNA-binding domain (16.7%)" RLEEVLNEVGMLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (20.4%) IPR003593 (20.4%) IPR015854 (20.4%)" "ABC transporter-like, ATP-binding domain (20.4%) AAA+ ATPase domain (20.4%) ABC transporter, lipoprotein release, LolD-like (20.4%)" VFDVVEEMPSFPGGQGALMSYLASNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (16.7%) GO:0015891 (16.7%) GO:0055085 (16.7%)" "GO:0030288 (16.7%) GO:0098797 (16.7%)" GO:0031992 (16.7%) "protein transport (16.7%) siderophore transport (16.7%) transmembrane transport (16.7%)" "outer membrane-bounded periplasmic space (16.7%) plasma membrane protein complex (16.7%)" energy transducer activity (16.7%) "IPR003538 (25%) IPR006260 (25%) IPR037682 (25%)" "Gram-negative bacterial TonB protein (25%) TonB/TolA, C-terminal (25%) TonB, C-terminal (25%)" LDETVDVDLLAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.4%) GO:0030163 (12.4%) GO:0051301 (0.6%)" GO:0005886 (12.4%) "GO:0004176 (12.4%) GO:0004222 (12.4%) GO:0005524 (12.4%)" "proteolysis (12.4%) protein catabolic process (12.4%) cell division (0.6%)" plasma membrane (12.4%) "ATP-dependent peptidase activity (12.4%) metalloendopeptidase activity (12.4%) ATP binding (12.4%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" LKPTFAFGHGLSYTQFALSNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" SDAMEDLSVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLTLACGGFYGPQGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.5%) IPR035994 (47.5%)" "Nucleoside phosphorylase domain (52.5%) Nucleoside phosphorylase superfamily (47.5%)" FGLADQVSYLSTGGGALLEALEGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" GLLLPGNNLMPSDVLEHLSELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR008979 (33.3%) IPR053161 (33.3%) IPR054593 (33.3%)" "Galactose-binding-like domain superfamily (33.3%) Ulvan-degrading glycoside hydrolase (33.3%) Beta-mannosidase-like, galactose-binding domain-like (33.3%)" TLGPDVNESYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006260 (33.3%) "GO:0003887 (33.3%) GO:0008408 (33.3%)" DNA replication (33.3%) "DNA-directed DNA polymerase activity (33.3%) 3'-5' exonuclease activity (33.3%)" "IPR004805 (12.8%) IPR011708 (12.8%) IPR029460 (12.8%)" "Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC (12.8%) Bacterial DNA polymerase III, alpha subunit, NTPase domain (12.8%) DNA polymerase, helix-hairpin-helix motif (12.8%)" VLLQSNCSLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016746 (100%) acyltransferase activity (100%) IPR016181 (100%) Acyl-CoA N-acyltransferase (100%) YFGDAEFLNNNLLHVHQPMVFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.1%) IPR033985 (33.3%) IPR011990 (31.6%)" "RagB/SusD domain (35.1%) SusD-like, N-terminal (33.3%) Tetratricopeptide-like helical domain superfamily (31.6%)" LYDDLSAK root "1.1.5.3 (33.3%) 3.1.6.- (33.3%) 3.4.21.- (33.3%)" "glycerol-3-phosphate dehydrogenase (33.3%) Sulfuric ester hydrolases (33.3%) Serine endopeptidases (33.3%)" "GO:0055085 (5%) GO:0015849 (4.3%) GO:0006508 (2.9%)" "GO:0005886 (23%) GO:0031317 (5%) GO:0016020 (1.4%)" "GO:0046872 (27.3%) GO:0016787 (14.4%) GO:0043177 (4.3%)" "transmembrane transport (5%) organic acid transport (4.3%) proteolysis (2.9%)" "plasma membrane (23%) tripartite ATP-independent periplasmic transporter complex (5%) membrane (1.4%)" "metal ion binding (27.3%) hydrolase activity (14.4%) organic acid binding (4.3%)" "IPR000917 (18.5%) IPR050448 (18.5%) IPR017850 (17.9%)" "Sulfatase, N-terminal (18.5%) OpgB/LTA synthase bacterial cell wall biosynthesis (18.5%) Alkaline-phosphatase-like, core domain superfamily (17.9%)" FGAMMNAR root GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR013830 (26.1%) IPR036514 (26.1%) IPR037459 (26.1%)" "SGNH hydrolase-type esterase domain (26.1%) SGNH hydrolase superfamily (26.1%) Rhamnogalacturonan acetylesterase RhgT-like (26.1%)" TDAPVVVDLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032342 (100%) Protein of unknown function DUF4861 (100%) VVVFDNADCEYSYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.3.1.98 (100%) UDP-N-acetylmuramate dehydrogenase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0051301 (14.3%)" GO:0005829 (14.3%) "GO:0008762 (14.3%) GO:0071949 (13.7%) GO:0050660 (0.5%)" "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) cell division (14.3%)" cytosol (14.3%) "UDP-N-acetylmuramate dehydrogenase activity (14.3%) FAD binding (13.7%) flavin adenine dinucleotide binding (0.5%)" "IPR003170 (13.1%) IPR006094 (13.1%) IPR011601 (13.1%)" "UDP-N-acetylenolpyruvoylglucosamine reductase (13.1%) FAD linked oxidase, N-terminal (13.1%) UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal (13.1%)" LGGALALGPLLQGLARPVNDLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (54.8%) GO:0008959 (45.2%)" "acetyltransferase activity (54.8%) phosphate acetyltransferase activity (45.2%)" "IPR002505 (16.9%) IPR004614 (16.9%) IPR050500 (16.9%)" "Phosphate acetyl/butaryl transferase (16.9%) Phosphate acetyltransferase (16.9%) Phosphate Acetyltransferase/Butyryltransferase (16.9%)" SPAGLFTEVTLPLEDLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) GVNDASFLPYSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR038726 (33.1%) IPR027417 (32.3%) IPR011604 (31.5%)" "PD-(D/E)XK endonuclease-like domain, AddAB-type (33.1%) P-loop containing nucleoside triphosphate hydrolase (32.3%) PD-(D/E)XK endonuclease-like domain superfamily (31.5%)" LLQNVADESER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006139 (20%) "GO:0003677 (20%) GO:0004386 (20%) GO:0005524 (20%)" nucleobase-containing compound metabolic process (20%) "DNA binding (20%) helicase activity (20%) ATP binding (20%)" "IPR006555 (25%) IPR006935 (25%) IPR014001 (25%)" "ATP-dependent helicase, C-terminal (25%) Helicase/UvrB, N-terminal (25%) Helicase superfamily 1/2, ATP-binding domain (25%)" DKEFYDVYQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016758 (100%) hexosyltransferase activity (100%) IPR004629 (100%) Glycosyl transferase WecG/TagA/CpsF (100%) ALHYCDELLNSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" SLLCLPEGAPLSK Bacteria Bacteria 4.3.1.19 (100%) threonine ammonia-lyase (100%) "GO:0006565 (16.7%) GO:0006567 (16.7%) GO:0009097 (16.7%)" "GO:0003941 (16.7%) GO:0004794 (16.7%) GO:0030170 (16.4%)" "L-serine catabolic process (16.7%) L-threonine catabolic process (16.7%) isoleucine biosynthetic process (16.7%)" "L-serine ammonia-lyase activity (16.7%) threonine deaminase activity (16.7%) pyridoxal phosphate binding (16.4%)" "IPR001926 (13.7%) IPR005789 (13.7%) IPR036052 (13.7%)" "Tryptophan synthase beta chain-like, PALP domain (13.7%) Threonine dehydratase, catabolic (13.7%) Tryptophan synthase beta chain-like, PALP domain superfamily (13.7%)" VLGFSDAK root "2.1.3.2 (88.7%) 2.7.13.3 (11.3%)" "aspartate carbamoyltransferase (88.7%) histidine kinase (11.3%)" "GO:0006207 (15.6%) GO:0006520 (15.6%) GO:0044205 (15.6%)" "GO:0005829 (14.8%) GO:0005886 (2.2%)" "GO:0004070 (15.6%) GO:0016597 (15.6%) GO:0000155 (2.2%)" "'de novo' pyrimidine nucleobase biosynthetic process (15.6%) amino acid metabolic process (15.6%) 'de novo' UMP biosynthetic process (15.6%)" "cytosol (14.8%) plasma membrane (2.2%)" "aspartate carbamoyltransferase activity (15.6%) amino acid binding (15.6%) phosphorelay sensor kinase activity (2.2%)" "IPR002082 (14.3%) IPR006130 (14.3%) IPR006131 (14.3%)" "Aspartate carbamoyltransferase (14.3%) Aspartate/ornithine carbamoyltransferase (14.3%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (14.3%)" AQLTEMLQEFFAERPGETLSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (25%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (25%)" "IPR001900 (12.6%) IPR003029 (12.6%) IPR004476 (12.6%)" "Ribonuclease II/R (12.6%) S1 domain (12.6%) Ribonuclease II/ribonuclease R (12.6%)" MDWLTPGLSVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ASETEMVTVAMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.8.1.10 (100%) thiazole synthase (100%) "GO:0009229 (29.7%) GO:0009228 (10.9%)" GO:0005737 (29.7%) "GO:1990107 (18.8%) GO:0016783 (10.9%)" "thiamine diphosphate biosynthetic process (29.7%) thiamine biosynthetic process (10.9%)" cytoplasm (29.7%) "thiazole synthase activity (18.8%) sulfurtransferase activity (10.9%)" "IPR008867 (33.9%) IPR033983 (33.9%) IPR013785 (32.1%)" "Thiazole synthase (33.9%) Thiazole synthase ThiG (33.9%) Aldolase-type TIM barrel (32.1%)" DEKGDELGFNSLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) AGTLLPFGPEVLYSSEKPWDELELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR000322 (12.5%) IPR011013 (12.5%) IPR013780 (12.5%)" "Glycoside hydrolase family 31, TIM barrel domain (12.5%) Galactose mutarotase-like domain superfamily (12.5%) Glycosyl hydrolase, all-beta (12.5%)" FSDGEFGVSFEESLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (11.1%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (11.1%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (16.9%) IPR000842 (16.9%) IPR005946 (16.9%)" "Phosphoribosyltransferase domain (16.9%) Phosphoribosyl pyrophosphate synthetase, conserved site (16.9%) Ribose-phosphate pyrophosphokinase (16.9%)" LMGLFFEDLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.2%) GO:0046556 (50.8%) L-arabinose metabolic process (49.2%) alpha-L-arabinofuranosidase activity (50.8%) "IPR051563 (17.1%) IPR055133 (17.1%) IPR010720 (16.6%)" "Glycosyl Hydrolase Family 51 (17.1%) Arabinosidase BT_3657-like, N-terminal (17.1%) Alpha-L-arabinofuranosidase, C-terminal (16.6%)" LASLTQPAKPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR043738 (100%) Domain of unknown function DUF5683 (100%) HPEVFVLADELYEHLNYLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.- (100%) Transaminases (100%) GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004838 (16.9%) IPR004839 (16.9%) IPR015421 (16.9%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.9%) Aminotransferase, class I/classII, large domain (16.9%) Pyridoxal phosphate-dependent transferase, major domain (16.9%)" NLYLTTQLLDMHLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (25.1%) "GO:0005525 (25.1%) GO:0015093 (25.1%) GO:0046914 (24.7%)" plasma membrane (25.1%) "GTP binding (25.1%) ferrous iron transmembrane transporter activity (25.1%) transition metal ion binding (24.7%)" "IPR005225 (9.3%) IPR030389 (9.3%) IPR050860 (9.3%)" "Small GTP-binding domain (9.3%) FeoB-type guanine nucleotide-binding (G) domain (9.3%) Fe(2+) Transporter FeoB GTPase (9.3%)" NSGLNCPLETVDPSVDMNHCVLNVSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR000253 (52%) IPR008984 (48%)" "Forkhead-associated (FHA) domain (52%) SMAD/FHA domain superfamily (48%)" FSSDDEKLTMTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QDAEAQLSWLDETLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.2 (100%) acid phosphatase (100%) "GO:0003993 (48.5%) GO:0046872 (48.5%) GO:0016787 (2.9%)" "acid phosphatase activity (48.5%) metal ion binding (48.5%) hydrolase activity (2.9%)" "IPR004843 (25.7%) IPR051558 (25.7%) IPR024927 (24.3%)" "Calcineurin-like, phosphoesterase domain (25.7%) Metallophosphoesterase Purple Acid Phosphatase (25.7%) Purple acid phosphatase (24.3%)" HAQNALGFHLTGAFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.1.1.190 (96.3%) 2.1.1.- (3.7%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (96.3%) Methyltransferases (3.7%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR002792 (17.3%) IPR010280 (17.3%) IPR030390 (16.7%)" "TRAM domain (17.3%) (Uracil-5)-methyltransferase family (17.3%) RNA methyltransferase TrmA, active site (16.7%)" AFVFPGQGSQFVGMGK Bacteria Bacteria 2.3.1.39 (100%) [acyl-carrier-protein] S-malonyltransferase (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004314 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) [acyl-carrier-protein] S-malonyltransferase activity (33.3%) "IPR014043 (14.6%) IPR050858 (14.6%) IPR001227 (14.3%)" "Acyl transferase domain (14.6%) Malonyl CoA-ACP Transacylase/Polyketide Synthase FabD (14.6%) Acyl transferase domain superfamily (14.3%)" EALEENKEFVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016491 (100%) oxidoreductase activity (100%) "IPR016446 (33.8%) IPR029479 (33.8%) IPR000415 (32.3%)" "Flavin oxidoreductase Frp family (33.8%) Nitroreductase (33.8%) Nitroreductase-like (32.3%)" NLAGEFLTMPENLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005507 (34.1%) GO:0016787 (34.1%) GO:0016740 (22%)" "copper ion binding (34.1%) hydrolase activity (34.1%) transferase activity (22%)" "IPR003730 (34.8%) IPR011324 (32.6%) IPR038371 (32.6%)" "Multi-copper polyphenol oxidoreductase (34.8%) Cytotoxic necrotizing factor-like, catalytic (32.6%) Multi-copper polyphenol oxidoreductase superfamily (32.6%)" RLELAFENQR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.6%) IPR012944 (33.6%) IPR033985 (32.9%)" "Tetratricopeptide-like helical domain superfamily (33.6%) RagB/SusD domain (33.6%) SusD-like, N-terminal (32.9%)" ACTVSEFTLEDCEVSNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (25%) IPR012334 (25%) IPR033427 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) Domain of unknown function DUF5123 (25%)" HYEELCEHCSEMEQLAQNAER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (23.9%) GO:0004540 (1.1%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (23.9%) RNA nuclease activity (1.1%)" "IPR001900 (12.9%) IPR022966 (12.9%) IPR050180 (12.9%)" "Ribonuclease II/R (12.9%) Ribonuclease II/R, conserved site (12.9%) RNR Ribonuclease (12.9%)" SLHTLSEAATEVCHYFYPQVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.6%) IPR022147 (14.6%) IPR052725 (14.6%)" "Glutamine synthetase, N-terminal domain (14.6%) Glutamine synthetase type III N-terminal (14.6%) Glutamine Synthetase Type-3 (14.6%)" TPLYGASNPWGSDFEPTLVWGPVEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" DTALYGLSSLLGR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005886 (93.2%) GO:0016020 (1.4%)" "GO:0015297 (2.7%) GO:0042910 (2.7%)" "plasma membrane (93.2%) membrane (1.4%)" "antiporter activity (2.7%) xenobiotic transmembrane transporter activity (2.7%)" "IPR050833 (53.1%) IPR002797 (45.3%) IPR002528 (1.6%)" "Polysaccharide Biosynthesis and Transport (53.1%) Polysaccharide biosynthesis protein (45.3%) Multi antimicrobial extrusion protein (1.6%)" TAVVKLDFLDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016787 (50.8%) GO:0030246 (49.2%)" "hydrolase activity (50.8%) carbohydrate binding (49.2%)" "IPR019563 (14.7%) IPR029483 (14.7%) IPR029486 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%)" KGFDVTVFEALHELGGVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (49.3%) GO:0051536 (49.3%) GO:0004355 (1.4%)" "oxidoreductase activity (49.3%) iron-sulfur cluster binding (49.3%) glutamate synthase (NADPH) activity (1.4%)" "IPR017927 (11.3%) IPR019480 (11.3%) IPR023753 (11.3%)" "FAD-binding domain, ferredoxin reductase-type (11.3%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.3%) FAD/NAD(P)-binding domain (11.3%)" VLSEDEFNRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR032252 (51.3%) IPR046357 (48.7%)" "Protein of unknown function DUF4827 (51.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (48.7%)" YVVVNATDGQPLAGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.8%) IPR051802 (19.8%) IPR001599 (19.1%)" "Macroglobulin domain (19.8%) Alpha-2-macroglobulin-like (19.8%) Alpha-2-macroglobulin (19.1%)" DLELDEEYWCAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006364 (20%) GO:0032259 (20%)" GO:0005737 (20%) "GO:0003723 (20%) GO:0008168 (20%)" "rRNA processing (20%) methylation (20%)" cytoplasm (20%) "RNA binding (20%) methyltransferase activity (20%)" "IPR002478 (16.7%) IPR015947 (16.7%) IPR019614 (16.7%)" "PUA domain (16.7%) PUA-like superfamily (16.7%) S-adenosylmethionine-dependent methyltransferase (16.7%)" CLLETGDLK root 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (28.6%) IPR011343 (28.6%) IPR013785 (28.6%)" "DeoC/FbaB/LacD aldolase (28.6%) Deoxyribose-phosphate aldolase (28.6%) Aldolase-type TIM barrel (28.6%)" YQYQTGSDCEVLLSLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" LAEELASR root "2.1.2.1 (10.5%) 2.7.7.48 (7.3%) 2.7.13.3 (5.6%)" "glycine hydroxymethyltransferase (10.5%) RNA-directed RNA polymerase (7.3%) histidine kinase (5.6%)" "GO:0016042 (6.4%) GO:0006559 (2.3%) GO:0006749 (2.3%)" "GO:0016020 (2.2%) GO:0005886 (1.3%) GO:0005829 (1.3%)" "GO:0003847 (6.4%) GO:0005524 (5.2%) GO:0003677 (2.6%)" "lipid catabolic process (6.4%) L-phenylalanine catabolic process (2.3%) glutathione metabolic process (2.3%)" "membrane (2.2%) plasma membrane (1.3%) cytosol (1.3%)" "1-alkyl-2-acetylglycerophosphocholine esterase activity (6.4%) ATP binding (5.2%) DNA binding (2.6%)" "IPR029058 (4.7%) IPR027417 (3.8%) IPR004045 (2.4%)" "Alpha/Beta hydrolase fold (4.7%) P-loop containing nucleoside triphosphate hydrolase (3.8%) Glutathione S-transferase, N-terminal (2.4%)" TNDTVEFEGETYPVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR002150 (25%) IPR027493 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL31 type A/B (25%) Large ribosomal subunit protein bL31 type B (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" VEDTGLGLKEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) "GO:0000155 (27.6%) GO:0003700 (26.9%) GO:0043565 (26.9%)" "phosphorelay sensor kinase activity (27.6%) DNA-binding transcription factor activity (26.9%) sequence-specific DNA binding (26.9%)" "IPR003594 (6.9%) IPR003661 (6.9%) IPR005467 (6.9%)" "Histidine kinase/HSP90-like ATPase domain (6.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.9%) Histidine kinase domain (6.9%)" LLTATAVDASTEDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (32.5%) GO:0045259 (32.5%)" "GO:0046933 (32.5%) GO:0016787 (2.5%)" "plasma membrane (32.5%) proton-transporting ATP synthase complex (32.5%)" "proton-transporting ATP synthase activity, rotational mechanism (32.5%) hydrolase activity (2.5%)" "IPR000711 (50%) IPR026015 (50%)" "ATPase, OSCP/delta subunit (50%) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily (50%)" TYTMPVTASWMVDLFGNLLSQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" LVQDMVSSAVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006298 (14.7%) GO:0032300 (14.3%) "GO:0005524 (14.7%) GO:0016887 (14.3%) GO:0030983 (14.3%)" mismatch repair (14.7%) mismatch repair complex (14.3%) "ATP binding (14.7%) ATP hydrolysis activity (14.3%) mismatched DNA binding (14.3%)" "IPR014790 (8.6%) IPR002099 (8.4%) IPR013507 (8.4%)" "MutL, C-terminal, dimerisation (8.6%) DNA mismatch repair protein MutL/Mlh/PMS (8.4%) DNA mismatch repair protein, S5 domain 2-like (8.4%)" LQSVPTLMLFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0045454 (33.3%) GO:0005829 (33.3%) GO:0015035 (33.3%) cell redox homeostasis (33.3%) cytosol (33.3%) protein-disulfide reductase activity (33.3%) "IPR013766 (33.5%) IPR036249 (32.9%) IPR005746 (32.4%)" "Thioredoxin domain (33.5%) Thioredoxin-like superfamily (32.9%) Thioredoxin (32.4%)" VYATHYAVGDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VFDDENHVMNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.1.96 (50%) 3.1.1.- (47.6%) 3.1.-.- (2.4%)" "D-aminoacyl-tRNA deacylase (50%) Carboxylic ester hydrolases (47.6%) Acting on ester bonds (2.4%)" GO:0019478 (16.4%) GO:0005737 (17.2%) "GO:0051500 (17.2%) GO:0000049 (16.4%) GO:0043908 (16.4%)" D-amino acid catabolic process (16.4%) cytoplasm (17.2%) "D-tyrosyl-tRNA(Tyr) deacylase activity (17.2%) tRNA binding (16.4%) Ser(Gly)-tRNA(Ala) hydrolase activity (16.4%)" "IPR003732 (50%) IPR023509 (50%)" "D-aminoacyl-tRNA deacylase DTD (50%) D-aminoacyl-tRNA deacylase-like superfamily (50%)" LTDTYKYQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (32.1%) GO:0009279 (67.9%) iron ion transport (32.1%) cell outer membrane (67.9%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VADAFFGEDVDAESLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.3.1 (100%) threonine synthase (100%) GO:0009088 (33.3%) "GO:0004795 (33.3%) GO:0030170 (33.3%)" threonine biosynthetic process (33.3%) "threonine synthase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000634 (14.5%) IPR001926 (14.5%) IPR004450 (14.5%)" "Serine/threonine dehydratase, pyridoxal-phosphate-binding site (14.5%) Tryptophan synthase beta chain-like, PALP domain (14.5%) Threonine synthase-like (14.5%)" VSFSEGSSVGDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) LMLFFLPR root "GO:0016020 (50%) GO:0005886 (25%)" GO:0022857 (25%) "membrane (50%) plasma membrane (25%)" transmembrane transporter activity (25%) "IPR007421 (27.1%) IPR038461 (25%) IPR038475 (24%)" "Schlafen, AlbA_2 domain (27.1%) Schlafen, AlbA_2 domain superfamily (25%) RecG, C-terminal domain superfamily (24%)" ETSPHVAEALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030435 (97.1%) GO:0030288 (2.9%) sporulation resulting in formation of a cellular spore (97.1%) outer membrane-bounded periplasmic space (2.9%) "IPR013486 (13%) IPR013693 (13%) IPR001173 (12.6%)" "Sporulation stage II protein D, amidase enhancer LytB (13%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (13%) Glycosyltransferase 2-like (12.6%)" LTPNYYFASTETGVAQMAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR011050 (57.7%) IPR012334 (42.3%)" "Pectin lyase fold/virulence factor (57.7%) Pectin lyase fold (42.3%)" LTYSYNLGGQLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (47.5%) GO:0005737 (47.5%) GO:0016020 (2.5%)" GO:0016787 (2.5%) "extracellular region (47.5%) cytoplasm (47.5%) membrane (2.5%)" hydrolase activity (2.5%) "IPR050708 (17.6%) IPR006530 (16.2%) IPR031325 (16.2%)" "Type VI secretion system VgrG/RHS (17.6%) YD repeat (16.2%) RHS repeat (16.2%)" QLSDALQSYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) YNQQLDVTKLPEGFDAYVVSTGTPTAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (33.3%) "GO:0016639 (33.3%) GO:0051536 (33.3%)" glutamate biosynthetic process (33.3%) "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (33.3%) iron-sulfur cluster binding (33.3%)" "IPR006005 (16.7%) IPR009051 (16.7%) IPR023753 (16.7%)" "Glutamate synthase, NADH/NADPH, small subunit 1 (16.7%) Alpha-helical ferredoxin (16.7%) FAD/NAD(P)-binding domain (16.7%)" KSLSELDDLLESLNLSFGTDLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011260 (16.7%) IPR011262 (16.7%) IPR011263 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (16.7%) DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%)" SVVALREPSLGPCFGMK Pseudomonadati Bacteria Pseudomonadati 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) GO:0035999 (33.3%) "GO:0004329 (33.3%) GO:0005524 (33.3%)" tetrahydrofolate interconversion (33.3%) "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (33.3%) IPR020628 (33.3%) IPR027417 (33.3%)" "Formate-tetrahydrofolate ligase, FTHFS (33.3%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" GTGTAADPFNVAGLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DLGTNPSEFAGVNPFQPSLELTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (50%) GO:0005886 (50%) cell division (50%) plasma membrane (50%) "IPR003838 (33.3%) IPR004513 (33.3%) IPR040690 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) Cell division protein FtsX (33.3%) FtsX, extracellular domain (33.3%)" FTAANGNSLFMPYTGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VGDALGGALTMDPTQPVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" GMVSFDYDSYYKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" QTWYGCEPVDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025970 (33.3%) IPR033404 (33.3%) IPR033407 (33.3%)" "SusE outer membrane protein (33.3%) Domain of unknown function DUF5111 (33.3%) Domain of unknown function DUF5114 (33.3%)" GTDGRLELYNEYGNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri WGLTNPAVDANVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (37.1%) IPR012547 (31.4%) IPR027417 (31.4%)" "AAA-ATPase-like domain (37.1%) PD-(D/E)XK nuclease superfamily 9 (31.4%) P-loop containing nucleoside triphosphate hydrolase (31.4%)" AGMTLTDEPGLYLAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (24.7%) GO:0005737 (25.3%) "GO:0070006 (25.3%) GO:0046872 (24.7%)" proteolysis (24.7%) cytoplasm (25.3%) "metalloaminopeptidase activity (25.3%) metal ion binding (24.7%)" "IPR000587 (12.7%) IPR000994 (12.7%) IPR032416 (12.7%)" "Creatinase, N-terminal (12.7%) Peptidase M24 (12.7%) Peptidase M24, C-terminal domain (12.7%)" DPHHPGSLGTALSEAVELATTTPGCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (22.1%) IPR006316 (22.1%) IPR023026 (22.1%)" "Tryptophan synthase beta chain-like, PALP domain (22.1%) Tryptophan synthase, beta chain-like (22.1%) Tryptophan synthase beta chain/beta chain-like (22.1%)" LSMLNPDACLLATPSDQALFNEDAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (41.5%) "GO:0004475 (41.5%) GO:0005525 (13.2%) GO:0016853 (3.8%)" GDP-mannose biosynthetic process (41.5%) "mannose-1-phosphate guanylyltransferase (GTP) activity (41.5%) GTP binding (13.2%) isomerase activity (3.8%)" "IPR005835 (25.9%) IPR051161 (25.9%) IPR029044 (24.7%)" "Nucleotidyl transferase domain (25.9%) Mannose-6-phosphate isomerase type 2 (25.9%) Nucleotide-diphospho-sugar transferases (24.7%)" TGLLPYRGDLTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (51.3%) IPR050811 (48.7%)" "PBP domain (51.3%) Phosphate-binding ABC transporter substrate-binding (48.7%)" TGQCAEFYQEMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" AHLLTGGYTSLTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) DGYGYLFGVNNTTVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" AVYLGDSDVDVMTAK Bacteria Bacteria 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) GO:0006281 (29.2%) GO:0005829 (29.2%) "GO:0008967 (29.2%) GO:2001070 (12.4%)" DNA repair (29.2%) cytosol (29.2%) "phosphoglycolate phosphatase activity (29.2%) starch binding (12.4%)" "IPR006439 (12.6%) IPR041492 (12.6%) IPR050155 (12.6%)" "HAD hydrolase, subfamily IA (12.6%) Haloacid dehalogenase-like hydrolase (12.6%) HAD-like hydrolase superfamily (12.6%)" MTADEPLLYGEKPAPGTVDPCTLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.5%) IPR012910 (13.5%) IPR023996 (13.5%)" "TonB-dependent receptor-like, beta-barrel (13.5%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%)" RLQEGFVVTDEPGVYFLPALLDDWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.11.9 (100%) Xaa-Pro aminopeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0030145 (25%) GO:0070006 (25%)" proteolysis (25%) cytosol (25%) "manganese ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000994 (20.4%) IPR007865 (20.4%) IPR052433 (20.4%)" "Peptidase M24 (20.4%) Aminopeptidase P, N-terminal (20.4%) Xaa-Pro dipeptidase-like (20.4%)" SELEDLSLK root "2.7.6.5 (88.2%) 3.1.7.2 (10.8%) 2.1.1.72 (1.1%)" "GTP diphosphokinase (88.2%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (10.8%) site-specific DNA-methyltransferase (adenine-specific) (1.1%)" "GO:0015969 (37.2%) GO:0015949 (0.6%) GO:0009307 (0.1%)" GO:0005886 (37.6%) "GO:0016787 (9.8%) GO:0016301 (8.8%) GO:0008728 (4.2%)" "guanosine tetraphosphate metabolic process (37.2%) nucleobase-containing small molecule interconversion (0.6%) DNA restriction-modification system (0.1%)" plasma membrane (37.6%) "hydrolase activity (9.8%) kinase activity (8.8%) GTP diphosphokinase activity (4.2%)" "IPR043519 (10%) IPR007685 (9.9%) IPR004095 (9.8%)" "Nucleotidyltransferase superfamily (10%) RelA/SpoT (9.9%) TGS (9.8%)" SLFASTLQAYFEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (41.8%) IPR012547 (35.7%) IPR027417 (22.5%)" "AAA-ATPase-like domain (41.8%) PD-(D/E)XK nuclease superfamily 9 (35.7%) P-loop containing nucleoside triphosphate hydrolase (22.5%)" ALANLQEQLAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VVASTFADKAAAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (9.1%) GO:0042834 (90.9%) cell division (9.1%) peptidoglycan binding (90.9%) "IPR007730 (50%) IPR036680 (50%)" "Sporulation-like domain (50%) Sporulation-like domain superfamily (50%)" VYGGTLTPTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016788 (94.6%) GO:0016787 (5.4%)" "hydrolase activity, acting on ester bonds (94.6%) hydrolase activity (5.4%)" "IPR013830 (33.9%) IPR053140 (33.9%) IPR036514 (32.1%)" "SGNH hydrolase-type esterase domain (33.9%) GDSL lipase Rv0518-like (33.9%) SGNH hydrolase superfamily (32.1%)" WSQNYLNGSNYANDLFPTLNAANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LELTFDDLWHTGER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR017039 (97.6%) IPR036388 (2.4%)" "Virulence factor BrkB (97.6%) Winged helix-like DNA-binding domain superfamily (2.4%)" GEEFDFQLDPEQAYGQHYDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0042026 (33.3%) GO:0005737 (33.3%) GO:0003755 (33.3%) protein refolding (33.3%) cytoplasm (33.3%) peptidyl-prolyl cis-trans isomerase activity (33.3%) "IPR001179 (33.3%) IPR046357 (33.3%) IPR048261 (33.3%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (33.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (33.3%) PPIase chaperone SlpA/SlyD-like, insertion domain superfamily (33.3%)" ALFYFHALDLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DFGQNYLMSLQEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR052724 (49.4%) IPR021280 (47.2%) IPR011990 (2.2%)" "Glycosyltransferase 117 domain-containing protein (49.4%) Protein O-mannosyl-transferase TMEM260-like (47.2%) Tetratricopeptide-like helical domain superfamily (2.2%)" TCYLYNDDLSLMPVLAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella YFVSAAYMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YLRPMLQEYLDVFGDNVLTHNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (50%) 1.6.5.9 (42.9%) 1.6.5.3 (7.1%)" "Transferred entry: 1.6.5.9 (50%) NADH:ubiquinone reductase (non-electrogenic) (42.9%) Transferred entry: 7.1.1.2 (7.1%)" GO:0005886 (25%) "GO:0048038 (25%) GO:0051287 (25%) GO:0008137 (24.2%)" plasma membrane (25%) "quinone binding (25%) NAD binding (25%) NADH dehydrogenase (ubiquinone) activity (24.2%)" "IPR001135 (20.3%) IPR022885 (20.3%) IPR029014 (20.3%)" "NADH-quinone oxidoreductase, subunit D (20.3%) NAD(P)H-quinone oxidoreductase subunit D/H (20.3%) [NiFe]-hydrogenase, large subunit (20.3%)" LGSSVEFDWCSVNALNTAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (53.2%) 6.3.4.16 (46.8%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (53.2%) carbamoyl-phosphate synthase (ammonia) (46.8%)" "GO:0006541 (14%) GO:0006221 (13.4%) GO:0006526 (13.4%)" GO:0005737 (14%) "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (13.7%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (13.4%) L-arginine biosynthetic process (13.4%)" cytoplasm (14%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (13.7%)" "IPR005480 (10.2%) IPR005479 (10%) IPR006275 (10%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.2%) Carbamoyl phosphate synthase, ATP-binding domain (10%) Carbamoyl-phosphate synthase, large subunit (10%)" SVLVDTLQAYFEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (52.4%) IPR012547 (47.6%)" "AAA-ATPase-like domain (52.4%) PD-(D/E)XK nuclease superfamily 9 (47.6%)" TSPFAFTGNRFEFR root "6.3.1.2 (98.1%) 5.4.4.3 (1.9%)" "glutamine synthetase (98.1%) 3-(hydroxyamino)phenol mutase (1.9%)" "GO:0006542 (48.9%) GO:0006979 (0.1%) GO:0006529 (0%)" "GO:0005737 (0.1%) GO:0005886 (0%) GO:0016020 (0%)" "GO:0004356 (49.9%) GO:0034022 (0.2%) GO:0004601 (0.1%)" "glutamine biosynthetic process (48.9%) response to oxidative stress (0.1%) obsolete asparagine biosynthetic process (0%)" "cytoplasm (0.1%) plasma membrane (0%) membrane (0%)" "glutamine synthetase activity (49.9%) 3-(hydroxyamino)phenol mutase activity (0.2%) peroxidase activity (0.1%)" "IPR008146 (14.4%) IPR052725 (14.3%) IPR014746 (14.3%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine Synthetase Type-3 (14.3%) Glutamine synthetase/guanido kinase, catalytic domain (14.3%)" ELDLNEMVENLANSFSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0007234 (16.7%) GO:0005886 (16.7%) "GO:0000155 (16.7%) GO:0000156 (16.7%) GO:0005524 (16.7%)" osmosensory signaling via phosphorelay pathway (16.7%) plasma membrane (16.7%) "phosphorelay sensor kinase activity (16.7%) phosphorelay response regulator activity (16.7%) ATP binding (16.7%)" "IPR003594 (15.2%) IPR003661 (15.2%) IPR005467 (15.2%)" "Histidine kinase/HSP90-like ATPase domain (15.2%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (15.2%) Histidine kinase domain (15.2%)" MQSVLSEELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (50%) GO:0004834 (50%) cytoplasm (50%) tryptophan synthase activity (50%) "IPR001926 (20%) IPR006653 (20%) IPR006654 (20%)" "Tryptophan synthase beta chain-like, PALP domain (20%) Tryptophan synthase, beta chain, conserved site (20%) Tryptophan synthase, beta chain (20%)" SEHFELNGYKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" YFYEAAELALLDTDVRR Pseudomonadati Bacteria Pseudomonadati 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.2%) GO:0005829 (33.2%) "GO:0008861 (33.2%) GO:0016829 (0.4%)" glucose metabolic process (33.2%) cytosol (33.2%) "formate C-acetyltransferase activity (33.2%) lyase activity (0.4%)" "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" AKLVTLGELMLR Bacteria Bacteria "2.7.1.45 (50%) 2.7.1.92 (50%)" "2-dehydro-3-deoxygluconokinase (50%) 5-dehydro-2-deoxygluconokinase (50%)" "GO:0016301 (97.5%) GO:0008673 (2.5%)" "kinase activity (97.5%) 2-dehydro-3-deoxygluconokinase activity (2.5%)" "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" NGDATNWQVSDLYLCDGSYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GQALGAAWYLPEER Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.1%) GO:0030163 (11.7%) GO:0051301 (3.2%)" "GO:0005886 (11.7%) GO:0016020 (0.1%) GO:0031966 (0.1%)" "GO:0004176 (12.1%) GO:0004222 (12.1%) GO:0005524 (12.1%)" "proteolysis (12.1%) protein catabolic process (11.7%) cell division (3.2%)" "plasma membrane (11.7%) membrane (0.1%) mitochondrial membrane (0.1%)" "ATP-dependent peptidase activity (12.1%) metalloendopeptidase activity (12.1%) ATP binding (12.1%)" "IPR000642 (10.1%) IPR003959 (10.1%) IPR003960 (10.1%)" "Peptidase M41 (10.1%) ATPase, AAA-type, core (10.1%) ATPase, AAA-type, conserved site (10.1%)" SMESGANASLKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0017038 (50%) GO:0005886 (50%) protein import (50%) plasma membrane (50%) "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" GNLLMNVLTGELNLQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.5%) GO:0005737 (19.2%) "GO:0004177 (20.5%) GO:0008270 (20.5%) GO:0008237 (19.2%)" proteolysis (20.5%) cytoplasm (19.2%) "aminopeptidase activity (20.5%) zinc ion binding (20.5%) metallopeptidase activity (19.2%)" "IPR001948 (51.6%) IPR023358 (48.4%)" "Peptidase M18 (51.6%) Peptidase M18, domain 2 (48.4%)" DSVDALLTAVCGALAEALEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) "GO:0022627 (26.7%) GO:0005840 (6.7%)" GO:0003735 (33.3%) translation (33.3%) "cytosolic small ribosomal subunit (26.7%) ribosome (6.7%)" structural constituent of ribosome (33.3%) "IPR001865 (27.8%) IPR023591 (27.8%) IPR005706 (22.2%)" "Small ribosomal subunit protein uS2 (27.8%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (27.8%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (22.2%)" ASVPSGASTGENEALELRDGDK Bacteria Bacteria 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.8%) "GO:0000015 (16.8%) GO:0005576 (16.6%) GO:0009986 (16.2%)" "GO:0000287 (16.8%) GO:0004634 (16.8%)" glycolytic process (16.8%) "phosphopyruvate hydratase complex (16.8%) extracellular region (16.6%) cell surface (16.2%)" "magnesium ion binding (16.8%) phosphopyruvate hydratase activity (16.8%)" "IPR000941 (16.7%) IPR020811 (16.7%) IPR029017 (16.7%)" "Enolase (16.7%) Enolase, N-terminal (16.7%) Enolase-like, N-terminal (16.7%)" NLSWAGNTVYSSAYLEALLGMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071709 (47.7%) "GO:0009279 (50%) GO:0019867 (2.3%)" membrane assembly (47.7%) "cell outer membrane (50%) outer membrane (2.3%)" "IPR010827 (25.8%) IPR034746 (25.8%) IPR039910 (24.7%)" "POTRA domain, BamA/TamA-like (25.8%) POTRA domain (25.8%) Surface antigen D15-like (24.7%)" PFSVLLFK root "5.2.1.8 (91.7%) 1.14.14.1 (8.3%)" "peptidylprolyl isomerase (91.7%) unspecific monooxygenase (8.3%)" "GO:0006457 (32.8%) GO:0006508 (1.6%)" "GO:0016020 (10.9%) GO:0005789 (3.1%) GO:0005886 (1.6%)" "GO:0003755 (32.8%) GO:0005506 (3.1%) GO:0008395 (3.1%)" "protein folding (32.8%) proteolysis (1.6%)" "membrane (10.9%) endoplasmic reticulum membrane (3.1%) plasma membrane (1.6%)" "peptidyl-prolyl cis-trans isomerase activity (32.8%) iron ion binding (3.1%) steroid hydroxylase activity (3.1%)" "IPR000774 (19.8%) IPR001179 (19.8%) IPR036944 (19.8%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (19.8%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (19.8%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (19.8%)" ELDLNNFQLEALGAGAYVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" SLMHSDGLLSQVLDHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0008299 (50%) "GO:0004659 (47.6%) GO:0106350 (2.4%)" isoprenoid biosynthetic process (50%) "prenyltransferase activity (47.6%) all-trans-octaprenyl-diphosphate synthase activity (2.4%)" "IPR000092 (33.9%) IPR033749 (33.9%) IPR008949 (32.3%)" "Polyprenyl synthetase-like (33.9%) Polyprenyl synthetase, conserved site (33.9%) Isoprenoid synthase domain superfamily (32.3%)" VDGDPLAR root 3.2.1.4 (100%) cellulase (100%) "GO:0061504 (21%) GO:0010467 (2.2%) GO:0098534 (2.2%)" "GO:0005634 (2.9%) GO:0016020 (2.9%) GO:0005737 (2.2%)" "GO:0061503 (21%) GO:0008641 (19.6%) GO:0016810 (8.7%)" "cyclic threonylcarbamoyladenosine biosynthetic process (21%) gene expression (2.2%) centriole assembly (2.2%)" "nucleus (2.9%) membrane (2.9%) cytoplasm (2.2%)" "tRNA threonylcarbamoyladenosine dehydratase (21%) ubiquitin-like modifier activating enzyme activity (19.6%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (8.7%)" "IPR045886 (13%) IPR000594 (12.6%) IPR035985 (12.1%)" "ThiF/MoeB/HesA family (13%) THIF-type NAD/FAD binding fold (12.6%) Ubiquitin-activating enzyme-like (12.1%)" GLLDAWK root "5.3.1.1 (67.9%) 5.6.2.4 (7.7%) 1.1.1.49 (4.8%)" "triose-phosphate isomerase (67.9%) DNA 3'-5' helicase (7.7%) glucose-6-phosphate dehydrogenase (NADP(+)) (4.8%)" "GO:0006094 (7%) GO:0006096 (7%) GO:0019563 (7%)" "GO:0005829 (11.5%) GO:0016020 (9.2%) GO:0005737 (3.6%)" "GO:0004807 (7%) GO:0016829 (2.1%) GO:0005524 (2%)" "gluconeogenesis (7%) glycolytic process (7%) glycerol catabolic process (7%)" "cytosol (11.5%) membrane (9.2%) cytoplasm (3.6%)" "triose-phosphate isomerase activity (7%) lyase activity (2.1%) ATP binding (2%)" "IPR013785 (8.8%) IPR000652 (6.7%) IPR020861 (6.7%)" "Aldolase-type TIM barrel (8.8%) Triosephosphate isomerase (6.7%) Triosephosphate isomerase, active site (6.7%)" ADDTLSVAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000917 (14.2%) GO:0043093 (14.1%) GO:0051258 (14.1%)" "GO:0005737 (14.3%) GO:0032153 (14.3%)" "GO:0003924 (14.3%) GO:0005525 (14.3%)" "division septum assembly (14.2%) FtsZ-dependent cytokinesis (14.1%) protein polymerization (14.1%)" "cytoplasm (14.3%) cell division site (14.3%)" "GTPase activity (14.3%) GTP binding (14.3%)" "IPR000158 (11.4%) IPR003008 (11.4%) IPR018316 (11.4%)" "Cell division protein FtsZ (11.4%) Tubulin/FtsZ, GTPase domain (11.4%) Tubulin/FtsZ, 2-layer sandwich domain (11.4%)" VQFEELMQTLNLPMDELQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.7%) GO:0005829 (32.7%) "GO:0008926 (32.7%) GO:0009026 (1.8%)" mannitol catabolic process (32.7%) cytosol (32.7%) "mannitol-1-phosphate 5-dehydrogenase activity (32.7%) tagaturonate reductase activity (1.8%)" "IPR013118 (22.2%) IPR013131 (22.2%) IPR008927 (18.5%)" "Mannitol dehydrogenase, C-terminal (22.2%) Mannitol dehydrogenase, N-terminal (22.2%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.5%)" YDLTGTELDAEADRLYHSAPGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (17.5%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (17.5%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (17.7%) IPR056740 (17.7%) IPR004404 (16.5%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.7%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.7%) Dihydroxy-acid dehydratase (16.5%)" LGGLVPEPEELVEALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.7 (100%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (100%) GO:0016491 (100%) oxidoreductase activity (100%) "IPR002880 (20%) IPR009014 (20%) IPR029061 (20%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (20%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (20%) Thiamin diphosphate-binding fold (20%)" HLPEVATVFTTHATSLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) DVYNMPAK Pseudomonadati Bacteria Pseudomonadati "3.4.24.- (88.2%) 5.6.2.2 (11.8%)" "Metalloendopeptidases (88.2%) DNA topoisomerase (ATP-hydrolyzing) (11.8%)" "GO:0006508 (11%) GO:0030163 (11%) GO:0006261 (1.5%)" "GO:0005886 (11%) GO:0005694 (1.5%) GO:0005737 (1.5%)" "GO:0005524 (12.5%) GO:0004176 (11%) GO:0004222 (11%)" "proteolysis (11%) protein catabolic process (11%) DNA-templated DNA replication (1.5%)" "plasma membrane (11%) chromosome (1.5%) cytoplasm (1.5%)" "ATP binding (12.5%) ATP-dependent peptidase activity (11%) metalloendopeptidase activity (11%)" "IPR000642 (8.4%) IPR003593 (8.4%) IPR003959 (8.4%)" "Peptidase M41 (8.4%) AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%)" NGVLLSNVTASQEVHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (23.9%) GO:0006508 (3%)" GO:0005737 (22.4%) "GO:0005506 (22.4%) GO:0061711 (14.9%) GO:0016747 (9%)" "tRNA threonylcarbamoyladenosine modification (23.9%) proteolysis (3%)" cytoplasm (22.4%) "iron ion binding (22.4%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (14.9%) acyltransferase activity, transferring groups other than amino-acyl groups (9%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" DCYTGFK root "5.4.2.2 (58.8%) 5.4.2.- (17.5%) 5.4.2.8 (3.1%)" "phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (58.8%) Phosphotransferases (phosphomutases) (17.5%) phosphomannomutase (3.1%)" "GO:0005975 (12.2%) GO:0006166 (12.2%) GO:0075523 (2.5%)" "GO:0033644 (2.4%) GO:0044220 (2.4%) GO:0016020 (1.3%)" "GO:0008973 (12.2%) GO:0000287 (11.9%) GO:0005524 (2.5%)" "carbohydrate metabolic process (12.2%) purine ribonucleoside salvage (12.2%) viral translational frameshifting (2.5%)" "host cell membrane (2.4%) host cell perinuclear region of cytoplasm (2.4%) membrane (1.3%)" "phosphopentomutase activity (12.2%) magnesium ion binding (11.9%) ATP binding (2.5%)" "IPR005846 (5.7%) IPR016055 (5.6%) IPR036900 (5.6%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (5.7%) Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III (5.6%) Alpha-D-phosphohexomutase, C-terminal domain superfamily (5.6%)" TMDCTGELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.9%) GO:0032045 (13.2%)" "GO:0003746 (14.9%) GO:0005525 (14.9%) GO:0000287 (14.2%)" "cytosol (14.9%) guanyl-nucleotide exchange factor complex (13.2%)" "translation elongation factor activity (14.9%) GTP binding (14.9%) magnesium ion binding (14.2%)" "IPR004160 (8.5%) IPR004161 (8.5%) IPR009000 (8.5%)" "Translation elongation factor EFTu/EF1A, C-terminal (8.5%) Translation elongation factor EFTu-like, domain 2 (8.5%) Translation protein, beta-barrel domain superfamily (8.5%)" QSPLVVGLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (12.9%) GO:0006047 (12.9%) GO:0006487 (12.9%)" GO:0005829 (12.9%) "GO:0004360 (12.9%) GO:0097367 (12.3%)" "fructose 6-phosphate metabolic process (12.9%) UDP-N-acetylglucosamine metabolic process (12.9%) protein N-linked glycosylation (12.9%)" cytosol (12.9%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.9%) carbohydrate derivative binding (12.3%)" "IPR017932 (13.1%) IPR001347 (12.5%) IPR005855 (12.5%)" "Glutamine amidotransferase type 2 domain (13.1%) SIS domain (12.5%) Glucosamine-fructose-6-phosphate aminotransferase, isomerising (12.5%)" RSGASESNTLVVGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.2.10 (100%) phosphoglucosamine mutase (100%) "GO:0005975 (14.3%) GO:0006048 (14.3%) GO:0009252 (14.3%)" GO:0005829 (14.3%) "GO:0000287 (14.3%) GO:0004615 (14.3%) GO:0008966 (14.3%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.3%) peptidoglycan biosynthetic process (14.3%)" cytosol (14.3%) "magnesium ion binding (14.3%) phosphomannomutase activity (14.3%) phosphoglucosamine mutase activity (14.3%)" "IPR005844 (10.4%) IPR016066 (10.4%) IPR050060 (10.4%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10.4%) Alpha-D-phosphohexomutase, conserved site (10.4%) Phosphoglucosamine mutase (10.4%)" LQVDGQLK root "1.4.1.13 (96.1%) 1.4.7.1 (2%) 1.4.1.14 (1.3%)" "glutamate synthase (NADPH) (96.1%) glutamate synthase (ferredoxin) (2%) glutamate synthase (NADH) (1.3%)" "GO:0006537 (19.4%) GO:0019676 (18.7%) GO:0048589 (0.1%)" "GO:0016020 (0.3%) GO:0009536 (0.1%)" "GO:0051538 (19.3%) GO:0046872 (19.1%) GO:0015930 (10.6%)" "glutamate biosynthetic process (19.4%) ammonia assimilation cycle (18.7%) developmental growth (0.1%)" "membrane (0.3%) plastid (0.1%)" "3 iron, 4 sulfur cluster binding (19.3%) metal ion binding (19.1%) glutamate synthase activity (10.6%)" "IPR002932 (12.5%) IPR002489 (12.4%) IPR013785 (12.3%)" "Glutamate synthase domain (12.5%) Glutamate synthase, alpha subunit, C-terminal (12.4%) Aldolase-type TIM barrel (12.3%)" CDGLSFELLEEALMQAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" THNDGVFDAYTPEMK Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.7%) GO:0005829 (33.7%) GO:0008861 (33.7%) glucose metabolic process (32.7%) cytosol (33.7%) formate C-acetyltransferase activity (33.7%) "IPR004184 (20.3%) IPR050244 (20.3%) IPR001150 (19.8%)" "Pyruvate formate lyase domain (20.3%) Autonomous Glycyl Radical Cofactor (20.3%) Glycine radical domain (19.8%)" GAHGYGGLWGGK Bacteria Bacteria "4.2.2.2 (66.7%) 3.1.1.11 (33.3%)" "pectate lyase (66.7%) pectinesterase (33.3%)" GO:0042545 (10%) "GO:0016829 (52.5%) GO:0004557 (25%) GO:0030599 (10%)" cell wall modification (10%) "lyase activity (52.5%) alpha-galactosidase activity (25%) pectinesterase activity (10%)" "IPR052063 (31.8%) IPR011050 (30.3%) IPR012334 (30.3%)" "Polysaccharide Lyase 1 (31.8%) Pectin lyase fold/virulence factor (30.3%) Pectin lyase fold (30.3%)" TYALQAGR root 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.9%) "GO:0005886 (19.1%) GO:0016020 (1%)" "GO:0003723 (20.1%) GO:0016787 (19.9%) GO:0004521 (18.9%)" mRNA catabolic process (19.9%) "plasma membrane (19.1%) membrane (1%)" "RNA binding (20.1%) hydrolase activity (19.9%) RNA endonuclease activity (18.9%)" "IPR006674 (12.5%) IPR006675 (12.5%) IPR003607 (12.5%)" "HD domain (12.5%) HDIG domain (12.5%) HD/PDEase domain (12.5%)" VLYHGNEWMTGLGVLYVNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) YLSDMNALEAMSTLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.7%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.7%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.9%) IPR003593 (10.9%) IPR004665 (10.9%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.9%) AAA+ ATPase domain (10.9%) Transcription termination factor Rho (10.9%)" ELSVEDFNK root "5.2.1.8 (96.8%) 2.7.1.3 (3.2%)" "peptidylprolyl isomerase (96.8%) ketohexokinase (3.2%)" "GO:0015031 (15.4%) GO:0043335 (15.4%) GO:0051083 (15.4%)" "GO:0005737 (5%) GO:0016020 (0.5%)" "GO:0003755 (15.4%) GO:0043022 (15.4%) GO:0044183 (15.4%)" "protein transport (15.4%) protein unfolding (15.4%) 'de novo' cotranslational protein folding (15.4%)" "cytoplasm (5%) membrane (0.5%)" "peptidyl-prolyl cis-trans isomerase activity (15.4%) ribosome binding (15.4%) protein folding chaperone (15.4%)" "IPR005215 (18.3%) IPR008881 (18.3%) IPR027304 (17.8%)" "Trigger factor (18.3%) Trigger factor, ribosome-binding, bacterial (18.3%) Trigger factor/SurA domain superfamily (17.8%)" TGVMVTPMQESGGLNLLTAQLEQNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) MGNLNSYSGATLCNTGYRDEDYTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016788 (88.9%) GO:0016787 (11.1%)" "hydrolase activity, acting on ester bonds (88.9%) hydrolase activity (11.1%)" "IPR032588 (52.9%) IPR036514 (47.1%)" "Putative GDSL-like Lipase/Acylhydrolase (52.9%) SGNH hydrolase superfamily (47.1%)" TAEWQPNTPLEK Bacteria Bacteria GO:0016020 (100%) membrane (100%) "IPR004291 (46.4%) IPR052344 (45.5%) IPR039552 (8.2%)" "Transposase IS66, central domain (46.4%) Transposase-related protein (45.5%) Transposase IS66, C-terminal (8.2%)" NNELYYMLNKALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" AVTGFFDYLEDLLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0003677 (100%) DNA binding (100%) "IPR011204 (95.7%) IPR003497 (4.3%)" "Virulence protein RhuM-like (95.7%) BRO N-terminal domain (4.3%)" MLDAYTR root "2.4.2.4 (78.9%) 2.4.2.2 (7%) 2.3.2.6 (5.3%)" "thymidine phosphorylase (78.9%) pyrimidine-nucleoside phosphorylase (7%) lysine/arginine leucyltransferase (5.3%)" "GO:0006206 (14.2%) GO:0006213 (14.2%) GO:0015074 (1.5%)" "GO:0005829 (15.1%) GO:0016020 (2.1%) GO:0005737 (0.9%)" "GO:0004645 (14.2%) GO:0009032 (14.2%) GO:0003676 (1.8%)" "pyrimidine nucleobase metabolic process (14.2%) pyrimidine nucleoside metabolic process (14.2%) DNA integration (1.5%)" "cytosol (15.1%) membrane (2.1%) cytoplasm (0.9%)" "1,4-alpha-oligoglucan phosphorylase activity (14.2%) thymidine phosphorylase activity (14.2%) nucleic acid binding (1.8%)" "IPR022558 (13.1%) IPR010870 (8.5%) IPR023614 (8.3%)" "Y03H (13.1%) Phosphate-selective porin O/P (8.5%) Porin domain superfamily (8.3%)" LQPLGLSR root "2.3.1.269 (54.9%) 2.7.2.11 (12.7%) 2.4.1.25 (9.9%)" "apolipoprotein N-acyltransferase (54.9%) glutamate 5-kinase (12.7%) 4-alpha-glucanotransferase (9.9%)" "GO:0042158 (7.5%) GO:0043200 (6.8%) GO:0006355 (5%)" "GO:0005829 (8.9%) GO:0005886 (7.7%) GO:0016020 (5%)" "GO:0043565 (14.3%) GO:0016410 (7.5%) GO:0015079 (4.1%)" "lipoprotein biosynthetic process (7.5%) response to amino acid (6.8%) regulation of DNA-templated transcription (5%)" "cytosol (8.9%) plasma membrane (7.7%) membrane (5%)" "sequence-specific DNA binding (14.3%) N-acyltransferase activity (7.5%) potassium ion transmembrane transporter activity (4.1%)" "IPR019887 (6.9%) IPR011008 (6.8%) IPR019888 (6.8%)" "Transcription regulator AsnC/Lrp, ligand binding domain (6.9%) Dimeric alpha-beta barrel (6.8%) Transcription regulator AsnC-like (6.8%)" DLLLELAPLPELGVNKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.9%) IPR039426 (14.9%) IPR008969 (13.5%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.9%) TonB-dependent receptor-like (14.9%) Carboxypeptidase-like, regulatory domain superfamily (13.5%)" FASEGANLAFTDLVLNDDMAAGLEATRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) GO:0006633 (33.3%) "GO:0004316 (33.3%) GO:0051287 (33.3%)" fatty acid biosynthetic process (33.3%) "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (33.3%) NAD binding (33.3%)" "IPR002347 (17.9%) IPR050259 (17.9%) IPR036291 (16.7%)" "Short-chain dehydrogenase/reductase SDR (17.9%) Short-chain dehydrogenases/reductases (17.9%) NAD(P)-binding domain superfamily (16.7%)" QGDWVDGGTWQNLFLHNFESSVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YLQTSYK root "3.2.1.1 (23.1%) 3.2.1.54 (15.4%) 2.4.1.19 (7.7%)" "alpha-amylase (23.1%) cyclomaltodextrinase (15.4%) cyclomaltodextrin glucanotransferase (7.7%)" "GO:0005975 (29.5%) GO:0006457 (1.5%) GO:0006914 (1.5%)" "GO:0016020 (6.4%) GO:0005886 (1.9%) GO:0005737 (1.1%)" "GO:0016798 (27.7%) GO:0004222 (5.3%) GO:0051082 (1.9%)" "carbohydrate metabolic process (29.5%) protein folding (1.5%) autophagy (1.5%)" "membrane (6.4%) plasma membrane (1.9%) cytoplasm (1.1%)" "hydrolase activity, acting on glycosyl bonds (27.7%) metalloendopeptidase activity (5.3%) unfolded protein binding (1.9%)" "IPR006047 (11.4%) IPR015171 (11.4%) IPR019492 (11.4%)" "Glycosyl hydrolase family 13, catalytic domain (11.4%) Cyclomaltodextrinase, N-terminal (11.4%) Cyclo-malto-dextrinase, C-terminal (11.4%)" ELEMDAVAK root "6.3.5.5 (26.3%) 6.3.4.16 (24.5%) 2.1.3.2 (23.8%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (26.3%) carbamoyl-phosphate synthase (ammonia) (24.5%) aspartate carbamoyltransferase (23.8%)" "GO:0006541 (9.3%) GO:0006526 (8.8%) GO:0006207 (8.5%)" "GO:0005951 (7.9%) GO:0005737 (1%) GO:0005829 (0.5%)" "GO:0004088 (9.4%) GO:0005524 (9.4%) GO:0046872 (9.4%)" "glutamine metabolic process (9.3%) L-arginine biosynthetic process (8.8%) 'de novo' pyrimidine nucleobase biosynthetic process (8.5%)" "carbamoyl-phosphate synthase complex (7.9%) cytoplasm (1%) cytosol (0.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (9.4%) ATP binding (9.4%) metal ion binding (9.4%)" "IPR005479 (4.9%) IPR011761 (4.9%) IPR005483 (4.8%)" "Carbamoyl phosphate synthase, ATP-binding domain (4.9%) ATP-grasp fold (4.9%) Carbamoyl phosphate synthase, CPSase domain (4.8%)" AFENLEVWFVTGAQLLYGGETVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" ETLPTDLPVVFLSSVTGQGLQELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (16.7%) GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" ribosome biogenesis (16.7%) cytoplasm (16.7%) "magnesium ion binding (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR006073 (12.5%) IPR006074 (12.5%) IPR006169 (12.5%)" "GTP binding domain (12.5%) GTP1/OBG, conserved site (12.5%) GTP1/OBG domain (12.5%)" YYDVQEGEVLLDGLNVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.6.3.- (50%) 3.6.3.44 (50%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (50%) Transferred entry: 7.6.2.2 (50%)" "GO:0005886 (22.2%) GO:0016020 (1.1%)" "GO:0005524 (23.2%) GO:0016887 (23.2%) GO:0015421 (16.2%)" "plasma membrane (22.2%) membrane (1.1%)" "ATP binding (23.2%) ATP hydrolysis activity (23.2%) ABC-type oligopeptide transporter activity (16.2%)" "IPR003439 (14.5%) IPR003593 (14.5%) IPR011527 (14.5%)" "ABC transporter-like, ATP-binding domain (14.5%) AAA+ ATPase domain (14.5%) ABC transporter type 1, transmembrane domain (14.5%)" LLLVLPCYNEEEVLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0005886 (50%) GO:0016757 (50%) plasma membrane (50%) glycosyltransferase activity (50%) "IPR001173 (33.8%) IPR050256 (33.8%) IPR029044 (32.3%)" "Glycosyltransferase 2-like (33.8%) Glycosyltransferase 2 (33.8%) Nucleotide-diphospho-sugar transferases (32.3%)" DKPYVSALR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005975 (49.8%) "GO:0004553 (41.5%) GO:0004565 (8.3%) GO:0016798 (0.5%)" carbohydrate metabolic process (49.8%) "hydrolase activity, hydrolyzing O-glycosyl compounds (41.5%) beta-galactosidase activity (8.3%) hydrolase activity, acting on glycosyl bonds (0.5%)" "IPR001944 (14.3%) IPR031330 (14.3%) IPR048912 (14.3%)" "Glycoside hydrolase, family 35 (14.3%) Glycoside hydrolase 35, catalytic domain (14.3%) Beta-galactosidase 1-like , first all-beta domain (14.3%)" LATGVDVR root "1.3.3.4 (33.3%) 2.3.1.129 (33.3%) 3.5.1.1 (33.3%)" "protoporphyrinogen oxidase (33.3%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (33.3%) asparaginase (33.3%)" "GO:0044718 (25.3%) GO:0006309 (2.3%) GO:0006528 (0.6%)" "GO:0009279 (25.9%) GO:0016020 (2.3%) GO:0005737 (0.6%)" "GO:0015344 (25.3%) GO:0004531 (2.9%) GO:0005319 (2.3%)" "siderophore transmembrane transport (25.3%) apoptotic DNA fragmentation (2.3%) asparagine metabolic process (0.6%)" "cell outer membrane (25.9%) membrane (2.3%) cytoplasm (0.6%)" "siderophore uptake transmembrane transporter activity (25.3%) deoxyribonuclease II activity (2.9%) lipid transporter activity (2.3%)" "IPR000531 (15.2%) IPR012910 (15.2%) IPR039426 (15.2%)" "TonB-dependent receptor-like, beta-barrel (15.2%) TonB-dependent receptor, plug domain (15.2%) TonB-dependent receptor-like (15.2%)" GVALVDGGYENPVKYEYVAFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006974 (52.8%) GO:0016020 (47.2%) DNA damage response (52.8%) membrane (47.2%) "IPR007497 (33.9%) IPR052022 (33.9%) IPR016907 (32.1%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.9%) 26 kDa periplasmic antigen-related (33.9%) Uncharacterised conserved protein UCP029033, periplasmic protein (32.1%)" AWAAFNLAK Bacteria Bacteria 4.1.1.44 (100%) 4-carboxymuconolactone decarboxylase (100%) "GO:0051920 (97.6%) GO:0047575 (2.4%)" "peroxiredoxin activity (97.6%) 4-carboxymuconolactone decarboxylase activity (2.4%)" "IPR003779 (20.2%) IPR029032 (19.8%) IPR047263 (19.3%)" "Carboxymuconolactone decarboxylase-like (20.2%) AhpD-like (19.8%) Hydroxynitrile lyase-like, cupin domain (19.3%)" VGSDVENLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.8%) IPR002772 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase, family 3, N-terminal (12.8%) Glycoside hydrolase family 3 C-terminal domain (12.8%) Fibronectin type III-like domain (12.8%)" NGLANTTMNDLAVASGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0003677 (100%) DNA binding (100%) "IPR001647 (33.3%) IPR009057 (33.3%) IPR050624 (33.3%)" "DNA-binding HTH domain, TetR-type (33.3%) Homedomain-like superfamily (33.3%) HTH-type Transcriptional Regulator (33.3%)" SLLVSTMQSYFEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (35.1%) IPR012547 (33.3%) IPR027417 (31.6%)" "AAA-ATPase-like domain (35.1%) PD-(D/E)XK nuclease superfamily 9 (33.3%) P-loop containing nucleoside triphosphate hydrolase (31.6%)" SNKQLYAQVLNDLTGTTLASASSLGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR005484 (33.7%) IPR057268 (33.7%) IPR004389 (32.6%)" "Large ribosomal subunit protein uL18, bacterial/plantae/animalia (33.7%) Large ribosomal subunit protein uL18 (33.7%) Large ribosomal subunit protein uL18, bacteria (32.6%)" QYNSLPASYHDAYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (47.1%) GO:0045493 (2.9%)" "GO:0016787 (47.1%) GO:0046559 (2.9%)" "carbohydrate metabolic process (47.1%) xylan catabolic process (2.9%)" "hydrolase activity (47.1%) alpha-glucuronidase activity (2.9%)" "IPR031924 (25%) IPR041437 (25%) IPR042301 (25%)" "Glycosyl hydrolase family 115 (25%) Gylcosyl hydrolase 115 C-terminal domain (25%) Glycosyl hydrolase 115 superfamily (25%)" HRGGLLGNVADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.1%) IPR033985 (35.1%) IPR011990 (29.7%)" "RagB/SusD domain (35.1%) SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (29.7%)" GVLVSVGGQLPNNLAMK Pseudomonadati Bacteria Pseudomonadati "6.3.5.5 (80.7%) 6.3.4.16 (19.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (80.7%) carbamoyl-phosphate synthase (ammonia) (19.3%)" "GO:0006541 (14%) GO:0006221 (11.9%) GO:0006526 (11.8%)" GO:0005737 (14%) "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (13.9%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (11.9%) L-arginine biosynthetic process (11.8%)" cytoplasm (14%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (13.9%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR011761 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) ATP-grasp fold (10.1%)" PLLVLAEDVDSEALTTLVVNR Bacteria Bacteria 5.6.1.7 (100%) chaperonin ATPase (100%) "GO:0042026 (20.5%) GO:0009408 (0.1%) GO:0051085 (0%)" "GO:0005737 (10.7%) GO:1990220 (0%)" "GO:0140662 (20.5%) GO:0005524 (20.3%) GO:0016853 (17%)" "protein refolding (20.5%) response to heat (0.1%) obsolete chaperone cofactor-dependent protein refolding (0%)" "cytoplasm (10.7%) GroEL-GroES complex (0%)" "ATP-dependent protein folding chaperone (20.5%) ATP binding (20.3%) isomerase activity (17%)" "IPR001844 (18.2%) IPR027409 (18%) IPR027413 (18%)" "Chaperonin Cpn60/GroEL (18.2%) GroEL-like apical domain superfamily (18%) GroEL-like equatorial domain superfamily (18%)" LRLEDYEPAFMEGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (20.1%) GO:0005829 (20.1%) "GO:0004180 (20.1%) GO:0004222 (20.1%) GO:0046872 (19.4%)" proteolysis (20.1%) cytosol (20.1%) "carboxypeptidase activity (20.1%) metalloendopeptidase activity (20.1%) metal ion binding (19.4%)" "IPR045090 (21.2%) IPR001567 (20.4%) IPR034005 (20.4%)" "Peptidase M3A/M3B (21.2%) Peptidase M3A/M3B catalytic domain (20.4%) Peptidyl-dipeptidase DCP (20.4%)" HQMEAAVSLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (28.3%) IPR008969 (26.4%) IPR037066 (26.4%)" "TonB-dependent receptor, plug domain (28.3%) Carboxypeptidase-like, regulatory domain superfamily (26.4%) TonB-dependent receptor, plug domain superfamily (26.4%)" DVELYPVLNALFEGLYGSNPYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR048441 (50%) IPR048496 (50%)" "DUF1846, C-terminal (50%) DUF1846, N-terminal domain (50%)" YTDDDLYNATFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.7%) GO:0005829 (16.7%) "GO:0003677 (16.7%) GO:0004527 (16.7%) GO:0005524 (16.7%)" recombinational repair (16.7%) cytosol (16.7%) "DNA binding (16.7%) exonuclease activity (16.7%) ATP binding (16.7%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" FLQSESLR root "GO:0015031 (10.4%) GO:0015833 (10.4%) GO:0055085 (10.4%)" "GO:0005886 (11.3%) GO:0000922 (5.7%) GO:0005814 (5.7%)" "GO:0016301 (16%) GO:0003677 (1.9%) GO:0008270 (1.9%)" "protein transport (10.4%) peptide transport (10.4%) transmembrane transport (10.4%)" "plasma membrane (11.3%) spindle pole (5.7%) centriole (5.7%)" "kinase activity (16%) DNA binding (1.9%) zinc ion binding (1.9%)" "IPR011611 (11.5%) IPR029056 (11.5%) IPR052700 (11.5%)" "Carbohydrate kinase PfkB (11.5%) Ribokinase-like (11.5%) Carbohydrate kinase PfkB-like (11.5%)" FDFLADGDYEALVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016798 (50%) GO:0030246 (50%)" "hydrolase activity, acting on glycosyl bonds (50%) carbohydrate binding (50%)" "IPR013780 (12.5%) IPR013785 (12.5%) IPR014718 (12.5%)" "Glycosyl hydrolase, all-beta (12.5%) Aldolase-type TIM barrel (12.5%) Glycoside hydrolase-type carbohydrate-binding (12.5%)" FVDLNNDGVLDSNDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" MLLDTSYDGFVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (50%) 3.4.24.- (50%)" "Acting on peptide bonds (peptidases) (50%) Metalloendopeptidases (50%)" GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR045090 (20.5%) IPR034005 (20%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidase M3A/M3B (20.5%) Peptidyl-dipeptidase DCP (20%)" QSSDALNLTETTTANYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" NVLTLYK root "2.7.7.85 (77.6%) 2.7.11.1 (10.9%) 3.2.1.39 (4.5%)" "diadenylate cyclase (77.6%) non-specific serine/threonine protein kinase (10.9%) glucan endo-1,3-beta-D-glucosidase (4.5%)" "GO:0015031 (6.3%) GO:0008333 (5.4%) GO:0006281 (2.8%)" "GO:0000813 (5.9%) GO:0031902 (2.3%) GO:0005829 (1.6%)" "GO:0043130 (5.4%) GO:0005524 (3.7%) GO:0003677 (2.9%)" "protein transport (6.3%) endosome to lysosome transport (5.4%) DNA repair (2.8%)" "ESCRT I complex (5.9%) late endosome membrane (2.3%) cytosol (1.6%)" "ubiquitin binding (5.4%) ATP binding (3.7%) DNA binding (2.9%)" "IPR016135 (8.7%) IPR052070 (8.3%) IPR008883 (8.2%)" "Ubiquitin-conjugating enzyme/RWD-like (8.7%) ESCRT-I complex UEV domain-containing protein (8.3%) Ubiquitin E2 variant, N-terminal (8.2%)" TVYSELLSDKNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (13.8%) IPR011659 (13.8%) IPR012393 (13.8%)" "Tail specific protease (13.8%) WD40-like beta-propeller (13.8%) Tricorn protease (13.8%)" VLSDQLGLNLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015969 (43.9%) GO:0005886 (43.9%) GO:0016787 (12.3%) guanosine tetraphosphate metabolic process (43.9%) plasma membrane (43.9%) hydrolase activity (12.3%) "IPR002912 (9.2%) IPR003607 (9.2%) IPR004095 (9.2%)" "ACT domain (9.2%) HD/PDEase domain (9.2%) TGS (9.2%)" ELNSLANYDFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.4%) GO:0005975 (1.6%)" "GO:0008422 (48.4%) GO:0004553 (1.6%)" "glucan catabolic process (48.4%) carbohydrate metabolic process (1.6%)" "beta-glucosidase activity (48.4%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.6%)" "IPR002772 (13%) IPR001764 (12.6%) IPR026891 (12.6%)" "Glycoside hydrolase family 3 C-terminal domain (13%) Glycoside hydrolase, family 3, N-terminal (12.6%) Fibronectin type III-like domain (12.6%)" NPQAQVLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" KNGFFLLNTLFDGEELVNFLPNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (13.9%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (13.9%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" VSPQSSDAEVEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" HYFGFDSFKGDQEALLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) "GO:0006281 (8.6%) GO:0006310 (8.6%) GO:0006260 (7.4%)" "GO:0005737 (8.6%) GO:0030894 (8.6%) GO:0043590 (8.6%)" "GO:0005524 (8.6%) GO:0009378 (8.6%) GO:0043138 (8.6%)" "DNA repair (8.6%) DNA recombination (8.6%) DNA replication (7.4%)" "cytoplasm (8.6%) replisome (8.6%) bacterial nucleoid (8.6%)" "ATP binding (8.6%) four-way junction helicase activity (8.6%) 3'-5' DNA helicase activity (8.6%)" "IPR011545 (8.2%) IPR014001 (8.2%) IPR004589 (7.6%)" "DEAD/DEAH-box helicase domain (8.2%) Helicase superfamily 1/2, ATP-binding domain (8.2%) DNA helicase, ATP-dependent, RecQ type (7.6%)" NVMSTDQELSFLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (50%) GO:0016798 (50%) xylan catabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR025112 (50%) IPR038653 (50%)" "Putative carbohydrate metabolism domain (50%) Putative carbohydrate metabolism domain superfamily (50%)" YEFDKSTTQQYSFNNDLVLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YVLNPWGPAACFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GLETPVLAK root 2.5.1.47 (100%) cysteine synthase (100%) GO:0006535 (45.5%) GO:0005737 (9.1%) "GO:0004124 (44.3%) GO:0016846 (1.1%)" cysteine biosynthetic process from serine (45.5%) cytoplasm (9.1%) "cysteine synthase activity (44.3%) carbon-sulfur lyase activity (1.1%)" "IPR001216 (16.9%) IPR001926 (16.9%) IPR050214 (16.9%)" "Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site (16.9%) Tryptophan synthase beta chain-like, PALP domain (16.9%) Cysteine synthase/Cystathionine beta-synthase (16.9%)" GYSVLLMEGQLDTPMVNMLEQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0051082 (24.7%)" "ATP binding (24.7%) ATP hydrolysis activity (24.7%) unfolded protein binding (24.7%)" "IPR001404 (20%) IPR020568 (20%) IPR020575 (20%)" "Heat shock protein Hsp90 family (20%) Ribosomal protein uS5 domain 2-type superfamily (20%) Heat shock protein Hsp90, N-terminal (20%)" TDVFSGNFPTWMLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LSDEELAARPQQPLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (16.9%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (16.9%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (16.9%) IPR020558 (16.9%) IPR056740 (16.9%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (16.9%)" LTFPDGSVR root "6.1.1.3 (99.6%) 6.3.2.10 (0.4%)" "threonine--tRNA ligase (99.6%) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (0.4%)" "GO:0006435 (16.4%) GO:0008360 (0.1%) GO:0009252 (0.1%)" "GO:0005737 (9.2%) GO:0005829 (7.3%)" "GO:0005524 (16.5%) GO:0000049 (16.5%) GO:0046872 (16.5%)" "threonyl-tRNA aminoacylation (16.4%) regulation of cell shape (0.1%) peptidoglycan biosynthetic process (0.1%)" "cytoplasm (9.2%) cytosol (7.3%)" "ATP binding (16.5%) tRNA binding (16.5%) metal ion binding (16.5%)" "IPR004095 (7.7%) IPR012675 (7.7%) IPR012676 (7.7%)" "TGS (7.7%) Beta-grasp domain superfamily (7.7%) TGS-like (7.7%)" ATVGSVGNSDHALEQSGKAGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0002181 (20%) GO:0015934 (20%) "GO:0003735 (20%) GO:0016740 (20%) GO:0019843 (20%)" cytoplasmic translation (20%) large ribosomal subunit (20%) "structural constituent of ribosome (20%) transferase activity (20%) rRNA binding (20%)" "IPR002171 (11.1%) IPR005880 (11.1%) IPR008991 (11.1%)" "Large ribosomal subunit protein uL2 (11.1%) Large ribosomal subunit protein uL2, bacteria/organella (11.1%) Translation protein SH3-like domain superfamily (11.1%)" VTLTFDYYNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" DVFLADSGYVLSMAQQDFEHLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006449 (16.4%) GO:0005829 (16.8%) "GO:0003924 (16.8%) GO:0005525 (16.8%) GO:0016150 (16.8%)" regulation of translational termination (16.4%) cytosol (16.8%) "GTPase activity (16.8%) GTP binding (16.8%) translation release factor activity, codon nonspecific (16.8%)" "IPR004548 (9.3%) IPR032090 (9.3%) IPR053905 (9.3%)" "Peptide chain release factor 3 (9.3%) Peptide chain release factor 3, C-terminal (9.3%) Elongation factor G-like, domain II (9.3%)" QLQLAFPDRELLGVDSQTLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) DLKELDAVGHR Bacteria Bacteria 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (16.8%) GO:0006085 (16.5%)" GO:0005737 (16.5%) "GO:0005524 (16.8%) GO:0008776 (16.8%) GO:0000287 (16.5%)" "acetate metabolic process (16.8%) acetyl-CoA biosynthetic process (16.5%)" cytoplasm (16.5%) "ATP binding (16.8%) acetate kinase activity (16.8%) magnesium ion binding (16.5%)" "IPR000890 (25.1%) IPR004372 (25.1%) IPR023865 (25.1%)" "Aliphatic acid kinase, short-chain (25.1%) Acetate/propionate kinase (25.1%) Aliphatic acid kinase, short-chain, conserved site (25.1%)" FSTQMGSQDAQWESLDTDRAEGCLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.2%) GO:0009099 (16.2%)" GO:0005829 (17.6%) "GO:0000287 (16.2%) GO:0004160 (16.2%) GO:0051537 (16.2%)" "isoleucine biosynthetic process (16.2%) L-valine biosynthetic process (16.2%)" cytosol (17.6%) "magnesium ion binding (16.2%) dihydroxy-acid dehydratase activity (16.2%) 2 iron, 2 sulfur cluster binding (16.2%)" "IPR000581 (17.9%) IPR056740 (17.9%) IPR004404 (16.4%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.9%) Dihydroxy-acid dehydratase (16.4%)" LLAAFYGLGTPELTLEELGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR000943 (10%) IPR007624 (10%) IPR007627 (10%)" "RNA polymerase sigma-70 (10%) RNA polymerase sigma-70 region 3 (10%) RNA polymerase sigma-70 region 2 (10%)" AETDSDGYMAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (50%) GO:1990351 (50%)" "cell outer membrane (50%) transporter complex (50%)" "IPR045659 (50%) IPR050218 (50%)" "LPS-assembly protein LptD, central domain (50%) Lipopolysaccharide Assembly Protein LptD (50%)" LALAQSHTEEAYYQAVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (21%) GO:0005737 (18.5%) "GO:0004177 (21%) GO:0008270 (21%) GO:0008237 (18.5%)" proteolysis (21%) cytoplasm (18.5%) "aminopeptidase activity (21%) zinc ion binding (21%) metallopeptidase activity (18.5%)" "IPR001948 (53.1%) IPR023358 (46.9%)" "Peptidase M18 (53.1%) Peptidase M18, domain 2 (46.9%)" TGQQNGLDDFYYSTLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" AGEWVNENNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0019698 (48.4%) "GO:0016829 (48.4%) GO:0016787 (3.2%)" D-galacturonate catabolic process (48.4%) "lyase activity (48.4%) hydrolase activity (3.2%)" "IPR007392 (20.1%) IPR013974 (20.1%) IPR044144 (20.1%)" "D-galactarate/Altronate dehydratase, second domain (20.1%) SAF domain (20.1%) UxaA/GarD, SAF domain (20.1%)" PMVDFLK root "2.7.1.130 (20%) 2.7.1.15 (20%) 3.2.1.39 (20%)" "tetraacyldisaccharide 4'-kinase (20%) ribokinase (20%) glucan endo-1,3-beta-D-glucosidase (20%)" "GO:0000272 (9.2%) GO:0006080 (8.9%) GO:0006289 (7%)" "GO:0005576 (3.3%) GO:0009986 (3.3%) GO:0016020 (2.2%)" "GO:0016985 (8.9%) GO:0005524 (7%) GO:0043138 (7%)" "polysaccharide catabolic process (9.2%) substituted mannan metabolic process (8.9%) nucleotide-excision repair (7%)" "extracellular region (3.3%) cell surface (3.3%) membrane (2.2%)" "mannan endo-1,4-beta-mannosidase activity (8.9%) ATP binding (7%) 3'-5' DNA helicase activity (7%)" "IPR017853 (11.9%) IPR001547 (11.6%) IPR022790 (10.6%)" "Glycoside hydrolase superfamily (11.9%) Glycoside hydrolase, family 5 (11.6%) Glycosyl hydrolase family 26 domain (10.6%)" VLNEAALR root "2.7.7.6 (85.1%) 3.4.24.- (6.1%) 3.4.11.1 (2%)" "DNA-directed RNA polymerase (85.1%) Metalloendopeptidases (6.1%) leucyl aminopeptidase (2%)" "GO:0006351 (11.4%) GO:0006508 (1.6%) GO:0030163 (1.1%)" "GO:0000428 (11.5%) GO:0005886 (1.7%) GO:0005737 (1.5%)" "GO:0003677 (12.9%) GO:0008270 (12%) GO:0003899 (11.4%)" "DNA-templated transcription (11.4%) proteolysis (1.6%) protein catabolic process (1.1%)" "DNA-directed RNA polymerase complex (11.5%) plasma membrane (1.7%) cytoplasm (1.5%)" "DNA binding (12.9%) zinc ion binding (12%) DNA-directed RNA polymerase activity (11.4%)" "IPR007081 (6.7%) IPR045867 (6.7%) IPR007083 (6.6%)" "RNA polymerase Rpb1, domain 5 (6.7%) DNA-directed RNA polymerase, subunit beta-prime (6.7%) RNA polymerase Rpb1, domain 4 (6.6%)" EANNQAQEEVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (52.2%) IPR012944 (47.8%)" "Tetratricopeptide-like helical domain superfamily (52.2%) RagB/SusD domain (47.8%)" FQVMLGMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.6%) IPR033985 (34.6%) IPR011990 (30.8%)" "RagB/SusD domain (34.6%) SusD-like, N-terminal (34.6%) Tetratricopeptide-like helical domain superfamily (30.8%)" NQVVDNNTLLDHQVGHCTSNELYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" MELLTPNELVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR018873 (100%) KilA-N, DNA-binding domain (100%) VSWTLDNLVYYNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" GLDGSENGKEAVLFDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008160 (50%) IPR032149 (50%)" "Collagen triple helix repeat (50%) Domain of unknown function DUF4988 (50%)" GLFSNEAGEGSAPNAAAVATVSHPVK Bacteria Bacteria GO:0005886 (50%) GO:0005283 (50%) plasma membrane (50%) amino acid:sodium symporter activity (50%) IPR001463 (100%) Sodium:alanine symporter (100%) GLGQQPCQYECPDFFQLPVNGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.8%) IPR013148 (14.8%) IPR018053 (14.8%)" "Glycoside hydrolase, family 32 (14.8%) Glycosyl hydrolase family 32, N-terminal (14.8%) Glycoside hydrolase, family 32, active site (14.8%)" DYHLSWLPTSYLLNPEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0004601 (100%) peroxidase activity (100%) "IPR012336 (20.5%) IPR013766 (20.5%) IPR050553 (20.5%)" "Thioredoxin-like fold (20.5%) Thioredoxin domain (20.5%) Thioredoxin family ResA/DsbE subfamily (20.5%)" DVSLKEYANEVLLLVNTATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.- (100%) Peroxidases (100%) GO:0034599 (50%) GO:0004601 (50%) cellular response to oxidative stress (50%) peroxidase activity (50%) "IPR000889 (29.1%) IPR029760 (29.1%) IPR036249 (29.1%)" "Glutathione peroxidase (29.1%) Glutathione peroxidase conserved site (29.1%) Thioredoxin-like superfamily (29.1%)" NLSPQVSEALVYALLTRPNVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002716 (33.3%) IPR002850 (33.3%) IPR029060 (33.3%)" "PIN domain (33.3%) MJ1680-like (33.3%) PIN-like domain superfamily (33.3%)" NASAVLLSYYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DLATELAATLAFSALQNNDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002881 (37%) IPR036465 (35.2%) IPR002035 (27.8%)" "Domain of unknown function DUF58 (37%) von Willebrand factor A-like domain superfamily (35.2%) von Willebrand factor, type A (27.8%)" SCGCTEVDYPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005737 (50%) GO:0042995 (50%)" "cytoplasm (50%) cell projection (50%)" "IPR011467 (34.8%) IPR013783 (32.6%) IPR053879 (32.6%)" "Protein of unknown function DUF1573 (34.8%) Immunoglobulin-like fold (32.6%) HYDIN/VesB/CFA65-like, Ig-like domain (32.6%)" VFDLVADR root 2.7.8.5 (100%) CDP-diacylglycerol--glycerol-3-phosphate 1-phosphatidyltransferase (100%) "GO:0008654 (14%) GO:0006753 (1.1%) GO:0019693 (1.1%)" "GO:0016020 (23.7%) GO:0005829 (2.2%)" "GO:0016780 (12.9%) GO:0000155 (11.8%) GO:0003700 (10.8%)" "phospholipid biosynthetic process (14%) nucleoside phosphate metabolic process (1.1%) ribose phosphate metabolic process (1.1%)" "membrane (23.7%) cytosol (2.2%)" "phosphotransferase activity, for other substituted phosphate groups (12.9%) phosphorelay sensor kinase activity (11.8%) DNA-binding transcription factor activity (10.8%)" "IPR000462 (7.8%) IPR043130 (7.8%) IPR048254 (7.8%)" "CDP-alcohol phosphatidyltransferase (7.8%) CDP-alcohol phosphatidyltransferase, transmembrane domain (7.8%) CDP-alcohol phosphatidyltransferase, conserved site (7.8%)" ENGTYHDANPYNPSSASR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) NLLTGFAR root "6.-.-.- (47.7%) 6.4.1.3 (41.6%) 2.7.4.1 (4%)" "Ligases (47.7%) propionyl-CoA carboxylase (41.6%) ATP-polyphosphate phosphotransferase (4%)" "GO:0015977 (12.5%) GO:0006633 (4.2%) GO:0009062 (1.3%)" "GO:0009317 (24.3%) GO:0005739 (1.6%) GO:0009358 (0.5%)" "GO:0004658 (26%) GO:0003989 (13.8%) GO:0016740 (9.5%)" "carbon fixation (12.5%) fatty acid biosynthetic process (4.2%) fatty acid catabolic process (1.3%)" "acetyl-CoA carboxylase complex (24.3%) mitochondrion (1.6%) polyphosphate kinase complex (0.5%)" "propionyl-CoA carboxylase activity (26%) acetyl-CoA carboxylase activity (13.8%) transferase activity (9.5%)" "IPR011763 (18.1%) IPR034733 (18.1%) IPR051047 (18.1%)" "Acetyl-coenzyme A carboxyltransferase, C-terminal (18.1%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.1%) Acyl-CoA Carboxylase Beta Subunit (18.1%)" ELMFSLSK root 5.3.3.2 (100%) isopentenyl-diphosphate Delta-isomerase (100%) "GO:0006353 (22.5%) GO:0031564 (21.7%) GO:0006355 (0.8%)" "GO:0005829 (22.5%) GO:0005634 (1.6%) GO:0005737 (1.6%)" "GO:0003723 (22.5%) GO:0000978 (0.8%) GO:0000981 (0.8%)" "DNA-templated transcription termination (22.5%) transcription antitermination (21.7%) regulation of DNA-templated transcription (0.8%)" "cytosol (22.5%) nucleus (1.6%) cytoplasm (1.6%)" "RNA binding (22.5%) RNA polymerase II cis-regulatory region sequence-specific DNA binding (0.8%) DNA-binding transcription factor activity, RNA polymerase II-specific (0.8%)" "IPR006027 (25.9%) IPR011605 (25.9%) IPR035926 (25%)" "NusB/RsmB/TIM44 (25.9%) NusB antitermination factor (25.9%) NusB-like superfamily (25%)" VKNADQLAPALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.6%) GO:0008360 (13.9%) GO:0009252 (13.9%)" GO:0005737 (13.9%) "GO:0005524 (14.6%) GO:0008716 (14.6%) GO:0046872 (14.6%)" "cell wall organization (14.6%) regulation of cell shape (13.9%) peptidoglycan biosynthetic process (13.9%)" cytoplasm (13.9%) "ATP binding (14.6%) D-alanine-D-alanine ligase activity (14.6%) metal ion binding (14.6%)" "IPR000291 (14.3%) IPR005905 (14.3%) IPR011095 (14.3%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.3%) D-alanine--D-alanine ligase (14.3%) D-alanine--D-alanine ligase, C-terminal (14.3%)" KGQNLQATLAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (50%) IPR024930 (50%)" "Chaperone protein Skp (50%) Skp domain superfamily (50%)" LALPNMLSFLATR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0019646 (14.3%) "GO:0005886 (14.3%) GO:0070069 (14.3%)" "GO:0009055 (14.3%) GO:0016682 (14.3%) GO:0020037 (14.3%)" aerobic electron transport chain (14.3%) "plasma membrane (14.3%) cytochrome complex (14.3%)" "electron transfer activity (14.3%) oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (14.3%) heme binding (14.3%)" IPR002585 (100%) Cytochrome ubiquinol oxidase subunit 1 (100%) LLSSVLANVNWNTQEADKLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (33.3%) GO:0006080 (33.3%)" GO:0016985 (33.3%) "polysaccharide catabolic process (33.3%) substituted mannan metabolic process (33.3%)" mannan endo-1,4-beta-mannosidase activity (33.3%) "IPR000805 (25%) IPR001547 (25%) IPR017853 (25%)" "Glycoside hydrolase family 26 (25%) Glycoside hydrolase, family 5 (25%) Glycoside hydrolase superfamily (25%)" TSTFDETWTPVWGENK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0030246 (50.7%) GO:0016787 (49.3%)" "carbohydrate binding (50.7%) hydrolase activity (49.3%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" DLQSYLDDALDLLEFANGPVTSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" AVVENLLR root "6.1.1.20 (72.7%) 2.5.1.78 (6.8%) 1.14.11.67 (4.5%)" "phenylalanine--tRNA ligase (72.7%) 6,7-dimethyl-8-ribityllumazine synthase (6.8%) [histone H3]-trimethyl-L-lysine(4) demethylase (4.5%)" "GO:0006432 (8.9%) GO:0000160 (0.9%) GO:0006355 (0.9%)" "GO:0009328 (8.9%) GO:0005829 (1.4%) GO:0005634 (0.9%)" "GO:0005524 (13.4%) GO:0000049 (9.1%) GO:0000287 (9.1%)" "phenylalanyl-tRNA aminoacylation (8.9%) phosphorelay signal transduction system (0.9%) regulation of DNA-templated transcription (0.9%)" "phenylalanine-tRNA ligase complex (8.9%) cytosol (1.4%) nucleus (0.9%)" "ATP binding (13.4%) tRNA binding (9.1%) magnesium ion binding (9.1%)" "IPR041616 (4.6%) IPR002547 (4.5%) IPR004532 (4.5%)" "Phenylalanyl tRNA synthetase beta chain, core domain (4.6%) tRNA-binding domain (4.5%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (4.5%)" LYQLGCNFSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR012547 (50%) IPR018631 (48.6%) IPR027417 (1.4%)" "PD-(D/E)XK nuclease superfamily 9 (50%) AAA-ATPase-like domain (48.6%) P-loop containing nucleoside triphosphate hydrolase (1.4%)" NAMALVNK root "2.4.1.227 (99.4%) 6.3.2.8 (0.6%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (99.4%) UDP-N-acetylmuramate--L-alanine ligase (0.6%)" "GO:0005975 (11.6%) GO:0008360 (11.6%) GO:0009252 (11.6%)" "GO:0005886 (11.6%) GO:0016020 (0.3%) GO:0005737 (0.1%)" "GO:0050511 (11.6%) GO:0051991 (6.8%) GO:0016758 (0.2%)" "carbohydrate metabolic process (11.6%) regulation of cell shape (11.6%) peptidoglycan biosynthetic process (11.6%)" "plasma membrane (11.6%) membrane (0.3%) cytoplasm (0.1%)" "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.6%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (6.8%) hexosyltransferase activity (0.2%)" "IPR007235 (32.7%) IPR004276 (32.2%) IPR006009 (32.2%)" "Glycosyl transferase, family 28, C-terminal (32.7%) Glycosyltransferase family 28, N-terminal domain (32.2%) N-acetylglucosaminyltransferase, MurG (32.2%)" NLVLTLDKLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TPAPEALKWVADECDALLQSGALPFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YDGKGPLVVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (67.5%) GO:0016740 (30.8%) GO:0016301 (1.7%)" "ATP binding (67.5%) transferase activity (30.8%) kinase activity (1.7%)" "IPR005337 (25.6%) IPR053931 (25.6%) IPR002575 (24.9%)" "RapZ-like family (25.6%) RapZ, C-terminal domain (25.6%) Aminoglycoside phosphotransferase (24.9%)" MDTLSYK root "1.2.1.27 (77.8%) 2.7.7.7 (11.1%) 3.1.-.- (11.1%)" "methylmalonate-semialdehyde dehydrogenase (CoA acylating) (77.8%) DNA-directed DNA polymerase (11.1%) Acting on ester bonds (11.1%)" "GO:0006412 (19.6%) GO:0017148 (19.6%) GO:0006210 (0.2%)" "GO:0022625 (19.6%) GO:0005739 (0.2%) GO:0016020 (0.1%)" "GO:0003735 (19.6%) GO:0003729 (19.6%) GO:0003676 (0.2%)" "translation (19.6%) negative regulation of translation (19.6%) thymine catabolic process (0.2%)" "cytosolic large ribosomal subunit (19.6%) mitochondrion (0.2%) membrane (0.1%)" "structural constituent of ribosome (19.6%) mRNA binding (19.6%) nucleic acid binding (0.2%)" "IPR005822 (25.2%) IPR005823 (25.1%) IPR036899 (25.1%)" "Large ribosomal subunit protein uL13 (25.2%) Large ribosomal subunit protein uL13, bacteria (25.1%) Large ribosomal subunit protein uL13 superfamily (25.1%)" FHDVVELSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) "GO:0005737 (30.3%) GO:0005739 (3%)" "GO:0005524 (33.3%) GO:0019136 (33.3%)" "cytoplasm (30.3%) mitochondrion (3%)" "ATP binding (33.3%) deoxynucleoside kinase activity (33.3%)" "IPR002624 (25%) IPR027417 (25%) IPR031314 (25%)" "Deoxynucleoside kinase (25%) P-loop containing nucleoside triphosphate hydrolase (25%) Deoxynucleoside kinase domain (25%)" LKLDLSDLELVDMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.7%) "GO:0016746 (17.4%) GO:0051287 (17.4%) GO:0046872 (16.7%)" malate metabolic process (16.7%) "acyltransferase activity (17.4%) NAD binding (17.4%) metal ion binding (16.7%)" "IPR002505 (9.3%) IPR012302 (9.3%) IPR036291 (9.3%)" "Phosphate acetyl/butaryl transferase (9.3%) Malic enzyme, NAD-binding (9.3%) NAD(P)-binding domain superfamily (9.3%)" PATATNLQPTVLFTVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.6%) "GO:0009279 (26.3%) GO:0046930 (24.6%)" GO:0015288 (24.6%) monoatomic ion transport (24.6%) "cell outer membrane (26.3%) pore complex (24.6%)" porin activity (24.6%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" NDGTFDFNTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (43.8%) GO:0000272 (6.3%)" GO:0004553 (50%) "xylan catabolic process (43.8%) polysaccharide catabolic process (6.3%)" hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001000 (32%) IPR017853 (28%) IPR044846 (28%)" "Glycoside hydrolase family 10 domain (32%) Glycoside hydrolase superfamily (28%) Glycoside hydrolase family 10 (28%)" GWSVNTQWTGAWNVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.1%) IPR012910 (12.1%) IPR023996 (12.1%)" "Carboxypeptidase-like, regulatory domain superfamily (12.1%) TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein, SusC/RagA (12.1%)" ELGAETLK root "6.1.1.20 (80%) 5.6.2.4 (3.6%) 1.1.1.100 (1.8%)" "phenylalanine--tRNA ligase (80%) DNA 3'-5' helicase (3.6%) 3-oxoacyl-[acyl-carrier-protein] reductase (1.8%)" "GO:0006432 (11.4%) GO:0006260 (0.5%) GO:0006281 (0.5%)" "GO:0009328 (11.4%) GO:0005886 (1.8%) GO:0016020 (1%)" "GO:0005524 (12.4%) GO:0000287 (11.4%) GO:0004826 (11.4%)" "phenylalanyl-tRNA aminoacylation (11.4%) DNA replication (0.5%) DNA repair (0.5%)" "phenylalanine-tRNA ligase complex (11.4%) plasma membrane (1.8%) membrane (1%)" "ATP binding (12.4%) magnesium ion binding (11.4%) phenylalanine-tRNA ligase activity (11.4%)" "IPR005146 (5.6%) IPR005147 (5.6%) IPR045060 (5.6%)" "B3/B4 tRNA-binding domain (5.6%) tRNA synthetase, B5-domain (5.6%) Phenylalanine-tRNA ligase, class IIc, beta subunit (5.6%)" SSWMETNYWDWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.9%) IPR033985 (31.6%) IPR012944 (29.1%)" "Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (31.6%) RagB/SusD domain (29.1%)" YDFMSDHSDGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (50.7%) IPR023614 (49.3%)" "Phosphate-selective porin O/P (50.7%) Porin domain superfamily (49.3%)" TSGQDEEHVHSDDLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" LQDYFAFLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (52.2%) IPR012944 (47.8%)" "Tetratricopeptide-like helical domain superfamily (52.2%) RagB/SusD domain (47.8%)" TLDGKDYLTTNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.148 (100%) thymidylate synthase (FAD) (100%) "GO:0006231 (18.4%) GO:0032259 (7.8%)" "GO:0004799 (18.4%) GO:0050660 (18.4%) GO:0050797 (18.4%)" "dTMP biosynthetic process (18.4%) methylation (7.8%)" "thymidylate synthase activity (18.4%) flavin adenine dinucleotide binding (18.4%) thymidylate synthase (FAD) activity (18.4%)" "IPR003669 (52.8%) IPR036098 (47.2%)" "Thymidylate synthase ThyX (52.8%) Thymidylate synthase ThyX superfamily (47.2%)" VDLDDLLAK root "3.6.4.13 (68.3%) 1.4.4.2 (31.7%)" "RNA helicase (68.3%) glycine dehydrogenase (aminomethyl-transferring) (31.7%)" "GO:0010467 (10.2%) GO:0042254 (10.2%) GO:0019464 (1.5%)" "GO:0005829 (12.1%) GO:0005634 (10.9%) GO:0005960 (1.5%)" "GO:0005524 (10.9%) GO:0016787 (10.9%) GO:0003723 (10.6%)" "gene expression (10.2%) ribosome biogenesis (10.2%) glycine decarboxylation via glycine cleavage system (1.5%)" "cytosol (12.1%) nucleus (10.9%) glycine cleavage complex (1.5%)" "ATP binding (10.9%) hydrolase activity (10.9%) RNA binding (10.6%)" "IPR045690 (9%) IPR032339 (8.7%) IPR001650 (8.5%)" "Protein of unknown function DUF6055 (9%) Domain of unknown function DUF4859 (8.7%) Helicase, C-terminal domain-like (8.5%)" HHAFHSHLLTK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001706 (25%) IPR018265 (25%) IPR021137 (25%)" "Large ribosomal subunit protein bL35 (25%) Large ribosomal subunit protein bL35, conserved site (25%) Large ribosomal subunit protein bL35-like (25%)" LQFSLVYR Bacteroidota Bacteria Pseudomonadati Bacteroidota "6.4.1.1 (71.4%) 2.1.3.1 (28.6%)" "pyruvate carboxylase (71.4%) methylmalonyl-CoA carboxytransferase (28.6%)" GO:0006094 (33%) GO:0005737 (33%) "GO:0004736 (33%) GO:0016740 (0.5%) GO:0047154 (0.5%)" gluconeogenesis (33%) cytoplasm (33%) "pyruvate carboxylase activity (33%) transferase activity (0.5%) methylmalonyl-CoA carboxytransferase activity (0.5%)" "IPR000891 (21%) IPR003379 (21%) IPR055268 (21%)" "Pyruvate carboxyltransferase (21%) Carboxylase, conserved domain (21%) Pyruvate carboxylase-like (21%)" MGDEFVSVEPLLLALVQGNSTAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (20%) GO:0042026 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0016887 (20%)" "cellular response to heat (20%) protein refolding (20%)" cytoplasm (20%) "ATP binding (20%) ATP hydrolysis activity (20%)" "IPR003593 (8.5%) IPR003959 (8.5%) IPR004176 (8.5%)" "AAA+ ATPase domain (8.5%) ATPase, AAA-type, core (8.5%) Clp, repeat (R) N-terminal domain (8.5%)" EYLEAVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" ANYTYTHSELTTSK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20.3%) IPR000531 (19.4%) IPR008969 (19.4%)" "TonB-dependent receptor, plug domain (20.3%) TonB-dependent receptor-like, beta-barrel (19.4%) Carboxypeptidase-like, regulatory domain superfamily (19.4%)" SGWQTGETPFYETAAGQAYLLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (46.2%) IPR012640 (30.8%) IPR013783 (23.1%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (46.2%) Membrane lipoprotein, lipid attachment site (30.8%) Immunoglobulin-like fold (23.1%)" TAYMFNPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VLGAVTDNGEFFEVQPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015977 (22.7%) GO:0006633 (6.7%)" GO:0009317 (22.7%) "GO:0004658 (25.3%) GO:0003989 (22.7%)" "carbon fixation (22.7%) fatty acid biosynthetic process (6.7%)" acetyl-CoA carboxylase complex (22.7%) "propionyl-CoA carboxylase activity (25.3%) acetyl-CoA carboxylase activity (22.7%)" "IPR011762 (19.4%) IPR011763 (19.4%) IPR034733 (19.4%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.4%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.4%)" MHEFGFTATEYQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (32%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (32%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" SDPSTPEVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.1.1.3 (50.8%) 2.7.2.4 (49.2%)" "homoserine dehydrogenase (50.8%) aspartate kinase (49.2%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" KLLHEDEVNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) LEAGETLVEEGTSCTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR000595 (14.7%) IPR012318 (14.7%) IPR018488 (14.7%)" "Cyclic nucleotide-binding domain (14.7%) Crp-type HTH domain (14.7%) Cyclic nucleotide-binding, conserved site (14.7%)" ATASDLGNLTSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (63.6%) IPR008160 (36.4%)" "Domain of unknown function DUF4988 (63.6%) Collagen triple helix repeat (36.4%)" HTLPGDFNLVSVDEVESLAGGNANGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" DSLPGSVLLGQFTNPANPAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.47 (100%) cysteine synthase (100%) GO:0006535 (46.7%) GO:0005737 (6.7%) "GO:0004124 (43.3%) GO:0016846 (3.3%)" cysteine biosynthetic process from serine (46.7%) cytoplasm (6.7%) "cysteine synthase activity (43.3%) carbon-sulfur lyase activity (3.3%)" "IPR001216 (17.1%) IPR001926 (17.1%) IPR036052 (17.1%)" "Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site (17.1%) Tryptophan synthase beta chain-like, PALP domain (17.1%) Tryptophan synthase beta chain-like, PALP domain superfamily (17.1%)" QLLDSLDR root "2.3.2.26 (20%) 1.2.1.41 (10%) 2.3.2.27 (10%)" "HECT-type E3 ubiquitin transferase (20%) glutamate-5-semialdehyde dehydrogenase (10%) RING-type E3 ubiquitin transferase (10%)" "GO:0006355 (3.6%) GO:0098003 (2.4%) GO:0032790 (1.8%)" "GO:0016020 (6.1%) GO:0005737 (5.5%) GO:0005739 (2.4%)" "GO:0043565 (5.2%) GO:0005525 (2.7%) GO:0003743 (1.8%)" "regulation of DNA-templated transcription (3.6%) viral tail assembly (2.4%) ribosome disassembly (1.8%)" "membrane (6.1%) cytoplasm (5.5%) mitochondrion (2.4%)" "sequence-specific DNA binding (5.2%) GTP binding (2.7%) translation initiation factor activity (1.8%)" "IPR000485 (2.4%) IPR027417 (2.4%) IPR036388 (2.4%)" "AsnC-type HTH domain (2.4%) P-loop containing nucleoside triphosphate hydrolase (2.4%) Winged helix-like DNA-binding domain superfamily (2.4%)" VECNQGKPQVNYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (20.3%) GO:0005737 (19.3%) "GO:0003746 (20.4%) GO:0005525 (20.3%) GO:0003924 (19.7%)" ribosome disassembly (20.3%) cytoplasm (19.3%) "translation elongation factor activity (20.4%) GTP binding (20.3%) GTPase activity (19.7%)" "IPR000640 (6.3%) IPR005517 (6.3%) IPR035649 (6.3%)" "Elongation factor EFG, domain V-like (6.3%) Translation elongation factor EFG/EF2, domain IV (6.3%) EFG, domain V (6.3%)" LVLDSDNHALDEVMVVAFGTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LPLEELNR root "2.7.11.1 (25.6%) 5.2.1.8 (15.4%) 6.3.5.5 (10.3%)" "non-specific serine/threonine protein kinase (25.6%) peptidylprolyl isomerase (15.4%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (10.3%)" "GO:0006357 (1%) GO:0006508 (0.8%) GO:0099111 (0.8%)" "GO:0005886 (4.1%) GO:0016020 (3.7%) GO:0005634 (3.5%)" "GO:0005524 (9.8%) GO:0004714 (3.7%) GO:0004674 (3.5%)" "regulation of transcription by RNA polymerase II (1%) proteolysis (0.8%) microtubule-based transport (0.8%)" "plasma membrane (4.1%) membrane (3.7%) nucleus (3.5%)" "ATP binding (9.8%) transmembrane receptor protein tyrosine kinase activity (3.7%) protein serine/threonine kinase activity (3.5%)" "IPR000719 (4.7%) IPR011009 (4.7%) IPR017441 (4.7%)" "Protein kinase domain (4.7%) Protein kinase-like domain superfamily (4.7%) Protein kinase, ATP binding site (4.7%)" NPLDNSAVHPER Pseudomonadati Bacteria Pseudomonadati "GO:0006412 (19.8%) GO:0006139 (18.9%) GO:0006281 (0.8%)" "GO:0005737 (19.8%) GO:0005840 (0.1%)" "GO:0003729 (19.8%) GO:0003735 (19.8%) GO:0003677 (0.8%)" "translation (19.8%) nucleobase-containing compound metabolic process (18.9%) DNA repair (0.8%)" "cytoplasm (19.8%) ribosome (0.1%)" "mRNA binding (19.8%) structural constituent of ribosome (19.8%) DNA binding (0.8%)" "IPR003029 (7.2%) IPR041692 (7.2%) IPR050437 (7.2%)" "S1 domain (7.2%) HHH domain 9 (7.2%) Small ribosomal subunit protein bS1-like (7.2%)" MLPHLALYLLHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016740 (91.7%) GO:0016746 (8.3%)" "transferase activity (91.7%) acyltransferase activity (8.3%)" "IPR001451 (50%) IPR011004 (45.8%) IPR045304 (4.2%)" "Hexapeptide repeat (50%) Trimeric LpxA-like superfamily (45.8%) Serine acetyltransferase, LbH domain (4.2%)" HYFEQVYATGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.5%) IPR019533 (25.5%) IPR019758 (25.5%)" "Peptidase S26A, signal peptidase I (25.5%) Peptidase S26 (25.5%) Peptidase S26A, signal peptidase I, conserved site (25.5%)" NGLLVDEAVAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.4%) IPR002890 (19.4%) IPR051802 (19.4%)" "Alpha-2-macroglobulin (19.4%) Macroglobulin domain (19.4%) Alpha-2-macroglobulin-like (19.4%)" TQVWDTPVNTVDAVYAFMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.2%) IPR051802 (19.2%) IPR002890 (18.7%)" "Alpha-2-macroglobulin (19.2%) Alpha-2-macroglobulin-like (19.2%) Macroglobulin domain (18.7%)" TFMVGLNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" LPTLTLVLKPTDNASYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015031 (32.1%) GO:0005886 (33.9%) GO:0022857 (33.9%) protein transport (32.1%) plasma membrane (33.9%) transmembrane transporter activity (33.9%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) NYPLNNAWLFGVEYFMHDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036777 (100%) Nucleoside-specific channel-forming protein, Tsx-like superfamily (100%) DLESEFSFQLTELQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.2%) GO:0043335 (15.4%) GO:0051083 (15.4%)" GO:0005737 (5.9%) "GO:0003755 (15.4%) GO:0043022 (15.4%) GO:0044183 (15.4%)" "protein transport (16.2%) protein unfolding (15.4%) 'de novo' cotranslational protein folding (15.4%)" cytoplasm (5.9%) "peptidyl-prolyl cis-trans isomerase activity (15.4%) ribosome binding (15.4%) protein folding chaperone (15.4%)" "IPR005215 (18.9%) IPR008881 (18.9%) IPR037041 (18.9%)" "Trigger factor (18.9%) Trigger factor, ribosome-binding, bacterial (18.9%) Trigger factor, C-terminal domain superfamily (18.9%)" SAVCFEAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.1.3.3 (95.5%) 5.1.3.- (4.5%)" "aldose 1-epimerase (95.5%) Acting on carbohydrates and derivatives (4.5%)" "GO:0006006 (20%) GO:0033499 (20%)" GO:0005737 (20%) "GO:0004034 (20%) GO:0030246 (20%)" "glucose metabolic process (20%) galactose catabolic process via UDP-galactose, Leloir pathway (20%)" cytoplasm (20%) "aldose 1-epimerase activity (20%) carbohydrate binding (20%)" "IPR008183 (20%) IPR011013 (20%) IPR014718 (20%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (20%) Galactose mutarotase-like domain superfamily (20%) Glycoside hydrolase-type carbohydrate-binding (20%)" LSDEELAAR root "4.2.1.9 (94%) 4.2.1.25 (1.5%) 4.2.1.- (1.3%)" "dihydroxy-acid dehydratase (94%) L-arabinonate dehydratase (1.5%) Hydro-lyases (1.3%)" "GO:0009097 (13.6%) GO:0009099 (13.6%) GO:0009082 (0.4%)" "GO:0005829 (11.2%) GO:0005737 (0.4%) GO:0005886 (0.2%)" "GO:0004160 (15.1%) GO:0051537 (13.9%) GO:0000287 (13.5%)" "isoleucine biosynthetic process (13.6%) L-valine biosynthetic process (13.6%) branched-chain amino acid biosynthetic process (0.4%)" "cytosol (11.2%) cytoplasm (0.4%) plasma membrane (0.2%)" "dihydroxy-acid dehydratase activity (15.1%) 2 iron, 2 sulfur cluster binding (13.9%) magnesium ion binding (13.5%)" "IPR056740 (15%) IPR042096 (14.8%) IPR000581 (14.8%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (15%) Dihydroxy-acid dehydratase, C-terminal (14.8%) Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (14.8%)" YDFLLNHFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.99.18 (100%) DNA-(apurinic or apyrimidinic site) lyase (100%) GO:0006285 (15.2%) "GO:0003677 (15.2%) GO:0019104 (15.2%) GO:0046872 (15.2%)" base-excision repair, AP site formation (15.2%) "DNA binding (15.2%) DNA N-glycosylase activity (15.2%) metal ion binding (15.2%)" "IPR003265 (14.5%) IPR003651 (14.5%) IPR004035 (14.5%)" "HhH-GPD domain (14.5%) Endonuclease III-like, iron-sulphur cluster loop motif (14.5%) Endonuclease III, iron-sulphur binding site (14.5%)" LQVVEGFR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (15%) GO:0007018 (0.9%)" "GO:0000428 (15%) GO:0005634 (1.8%) GO:0005737 (1.8%)" "GO:0003677 (15%) GO:0003899 (15%) GO:0008270 (14.5%)" "DNA-templated transcription (15%) microtubule-based movement (0.9%)" "DNA-directed RNA polymerase complex (15%) nucleus (1.8%) cytoplasm (1.8%)" "DNA binding (15%) DNA-directed RNA polymerase activity (15%) zinc ion binding (14.5%)" "IPR006592 (8.5%) IPR007080 (8.5%) IPR045867 (8.5%)" "RNA polymerase, N-terminal (8.5%) RNA polymerase Rpb1, domain 1 (8.5%) DNA-directed RNA polymerase, subunit beta-prime (8.5%)" NYDSLNYEFLAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006139 (20%) "GO:0003677 (20%) GO:0004386 (20%) GO:0005524 (20%)" nucleobase-containing compound metabolic process (20%) "DNA binding (20%) helicase activity (20%) ATP binding (20%)" "IPR006555 (25%) IPR006935 (25%) IPR014001 (25%)" "ATP-dependent helicase, C-terminal (25%) Helicase/UvrB, N-terminal (25%) Helicase superfamily 1/2, ATP-binding domain (25%)" SFFEEGKWTGSDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR025324 (100%) Protein of unknown function DUF4230 (100%) YWGFDPELSSGGTSLGVDYGVYPQAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SGVVGRASVPSGASTGENEALELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.9%) "GO:0000015 (16.9%) GO:0005576 (16.2%) GO:0009986 (16.2%)" "GO:0000287 (16.9%) GO:0004634 (16.9%)" glycolytic process (16.9%) "phosphopyruvate hydratase complex (16.9%) extracellular region (16.2%) cell surface (16.2%)" "magnesium ion binding (16.9%) phosphopyruvate hydratase activity (16.9%)" "IPR000941 (17.1%) IPR020811 (17.1%) IPR029017 (17.1%)" "Enolase (17.1%) Enolase, N-terminal (17.1%) Enolase-like, N-terminal (17.1%)" YSLLHYFGDEGVNDNAATDLLNNMGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DWDASFDFFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009228 (25%) "GO:0003824 (25%) GO:0005506 (25%) GO:0051539 (25%)" thiamine biosynthetic process (25%) "catalytic activity (25%) iron ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR007197 (21.4%) IPR010722 (21.4%) IPR012726 (21.4%)" "Radical SAM (21.4%) Biotin and thiamin synthesis-associated domain (21.4%) Thiazole biosynthesis ThiH (21.4%)" VHFDNTYGAYNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0001681 (50%) carbohydrate metabolic process (50%) sialate O-acetylesterase activity (50%) "IPR039329 (34.3%) IPR005181 (33.3%) IPR036514 (32.3%)" "Sialate O-acetylesterase (34.3%) Sialate O-acetylesterase domain (33.3%) SGNH hydrolase superfamily (32.3%)" LLKLPESK root "1.17.2.1 (8.3%) 2.1.1.- (8.3%) 2.7.10.2 (8.3%)" "nicotinate dehydrogenase (cytochrome) (8.3%) Methyltransferases (8.3%) non-specific protein-tyrosine kinase (8.3%)" "GO:0046654 (2.6%) GO:0046656 (2.6%) GO:0007166 (1.5%)" "GO:0016020 (15%) GO:0005886 (4.9%) GO:0005737 (4.1%)" "GO:0005524 (7.5%) GO:0046872 (5.6%) GO:0003848 (2.6%)" "tetrahydrofolate biosynthetic process (2.6%) folic acid biosynthetic process (2.6%) cell surface receptor signaling pathway (1.5%)" "membrane (15%) plasma membrane (4.9%) cytoplasm (4.1%)" "ATP binding (7.5%) metal ion binding (5.6%) 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity (2.6%)" "IPR013783 (3%) IPR003598 (2.8%) IPR003599 (2.8%)" "Immunoglobulin-like fold (3%) Immunoglobulin subtype 2 (2.8%) Immunoglobulin domain subtype (2.8%)" ESDKFWNFER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.2.29 (100%) peptidoglycan lytic transglycosylase (100%) "GO:0071555 (25.3%) GO:0009252 (24.2%)" GO:0005886 (25.3%) "GO:0008932 (24.2%) GO:0016829 (1%)" "cell wall organization (25.3%) peptidoglycan biosynthetic process (24.2%)" plasma membrane (25.3%) "lytic endotransglycosylase activity (24.2%) lyase activity (1%)" IPR003770 (100%) Endolytic murein transglycosylase (100%) QEWVDEYREWAATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (35%) IPR043148 (32.5%) IPR051612 (32.5%)" "CDP-glycerol glycerophosphotransferase (35%) CDP-glycerol glycerophosphotransferase, C-terminal domain (32.5%) Teichoic Acid Biosynthesis Enzymes (32.5%)" YYFYFPAAPK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.4 (100%) cellulase (100%) "GO:0045493 (24.2%) GO:0030245 (19.7%)" "GO:0004553 (24.2%) GO:0030246 (23.5%) GO:0016829 (8.3%)" "xylan catabolic process (24.2%) cellulose catabolic process (19.7%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (24.2%) carbohydrate binding (23.5%) lyase activity (8.3%)" "IPR006710 (14.3%) IPR052176 (14.3%) IPR005084 (13.8%)" "Glycoside hydrolase, family 43 (14.3%) Glycosyl Hydrolase Family 43 Enzymes (14.3%) Carbohydrate binding module family 6 (13.8%)" TTLVLYGSSTGSCQSLAETLASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0010181 (52.2%) GO:0009055 (47.8%)" "FMN binding (52.2%) electron transfer activity (47.8%)" "IPR008254 (20.7%) IPR010086 (20.7%) IPR050619 (20.7%)" "Flavodoxin/nitric oxide synthase (20.7%) Flavodoxin, long chain (20.7%) Flavodoxin (20.7%)" QAQVDYGREEQLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" PVSGLAMGLLK root 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.2%) GO:0006401 (0%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.2%) RNA catabolic process (0%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR012162 (8%) IPR015847 (8%) IPR004087 (7.9%)" "Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 2 (8%) K Homology domain (7.9%)" KQFGAEPFELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" LQDLLDDEDVTNVVYSYSETYQPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" TVFPLELNTMPGFAGSSAYYLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) "GO:0005829 (20%) GO:0005739 (0.1%)" "GO:0004823 (20%) GO:0005524 (20%) GO:0002161 (19.8%)" leucyl-tRNA aminoacylation (20%) "cytosol (20%) mitochondrion (0.1%)" "leucine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.8%)" "IPR002302 (12.6%) IPR013155 (12.5%) IPR001412 (12.4%)" "Leucine-tRNA ligase (12.6%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.5%) Aminoacyl-tRNA synthetase, class I, conserved site (12.4%)" EMQSAGSSGEFYTPR Pseudomonadati Bacteria Pseudomonadati "2.1.1.72 (95.7%) 2.1.1.- (4.3%)" "site-specific DNA-methyltransferase (adenine-specific) (95.7%) Methyltransferases (4.3%)" "GO:0009307 (21.6%) GO:0032259 (21.6%)" "GO:0003677 (21.6%) GO:0008170 (21.6%) GO:0009007 (12.7%)" "DNA restriction-modification system (21.6%) methylation (21.6%)" "DNA binding (21.6%) N-methyltransferase activity (21.6%) site-specific DNA-methyltransferase (adenine-specific) activity (12.7%)" "IPR002052 (17.2%) IPR003356 (17.2%) IPR051537 (17.2%)" "DNA methylase, N-6 adenine-specific, conserved site (17.2%) DNA methylase, adenine-specific (17.2%) DNA Adenine N(4)/N(6)-Methyltransferase (17.2%)" TNLDEFPQFFNVLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.8.31 (100%) undecaprenyl-phosphate glucose phosphotransferase (100%) GO:0016020 (50%) "GO:0016780 (37.9%) GO:0089702 (12.1%)" membrane (50%) "phosphotransferase activity, for other substituted phosphate groups (37.9%) undecaprenyl-phosphate glucose phosphotransferase activity (12.1%)" "IPR003362 (34.7%) IPR017475 (33.7%) IPR017473 (31.6%)" "Bacterial sugar transferase (34.7%) Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase (33.7%) Undecaprenyl-phosphate glucose phosphotransferase, WcaJ (31.6%)" DASGEPLMGATLTVNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR039426 (13.2%) IPR000531 (12.5%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent receptor-like (13.2%) TonB-dependent receptor-like, beta-barrel (12.5%)" SLMQLAEDLGMKVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (16.5%) GO:0009098 (16.5%) GO:0009099 (16.5%)" "GO:0004084 (17.9%) GO:0052654 (6%) GO:0052655 (6%)" "isoleucine biosynthetic process (16.5%) L-leucine biosynthetic process (16.5%) L-valine biosynthetic process (16.5%)" "branched-chain-amino-acid transaminase activity (17.9%) L-leucine-2-oxoglutarate transaminase activity (6%) L-valine-2-oxoglutarate transaminase activity (6%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" DASGEASYALLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" AMQYAGNFMNELYLNAHVVDNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR027304 (25.8%) IPR046357 (25.8%) IPR052029 (25.8%)" "Trigger factor/SurA domain superfamily (25.8%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.8%) Periplasmic chaperone PpiD (25.8%)" FTGNVYAELEPLKNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" GFANLNTNDLESVEVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (23.5%) GO:0009279 (76.5%) iron ion transport (23.5%) cell outer membrane (76.5%) "IPR012910 (12.4%) IPR023996 (12.4%) IPR023997 (12.4%)" "TonB-dependent receptor, plug domain (12.4%) TonB-dependent outer membrane protein, SusC/RagA (12.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.4%)" HFFGDYMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009100 (100%) glycoprotein metabolic process (100%) "IPR007074 (50%) IPR052942 (47.1%) IPR043519 (2.9%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (50%) Lipopolysaccharide cholinephosphotransferase (47.1%) Nucleotidyltransferase superfamily (2.9%)" TFGVEVVDKQSNALEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032283 (34.3%) IPR032299 (32.9%) IPR038081 (32.9%)" "Domain of unknown function DUF4984 (34.3%) Protein of unknown function DUF4843 (32.9%) CalX-like domain superfamily (32.9%)" QQELDLVELSPNAQPPVCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20%) "GO:0005829 (20%) GO:0016020 (20%)" "GO:0003743 (20%) GO:0043022 (20%)" ribosome disassembly (20%) "cytosol (20%) membrane (20%)" "translation initiation factor activity (20%) ribosome binding (20%)" "IPR001288 (16.9%) IPR019813 (16.9%) IPR019814 (16.9%)" "Translation initiation factor 3 (16.9%) Translation initiation factor 3, conserved site (16.9%) Translation initiation factor 3, N-terminal (16.9%)" LQDYFAFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (52.2%) IPR012944 (47.8%)" "Tetratricopeptide-like helical domain superfamily (52.2%) RagB/SusD domain (47.8%)" AELLDLYVYAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (32%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (32%)" "IPR033403 (11.6%) IPR000322 (11.3%) IPR025887 (11.3%)" "Domain of unknown function DUF5110 (11.6%) Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%)" EYQQNVEQLRDAEAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) PDLMLTGR root "6.3.1.2 (96.9%) 5.3.3.2 (3.1%)" "glutamine synthetase (96.9%) isopentenyl-diphosphate Delta-isomerase (3.1%)" "GO:0006542 (48%) GO:0043165 (0.5%) GO:0009240 (0.2%)" "GO:0005886 (0.5%) GO:0030288 (0.5%) GO:0005737 (0.2%)" "GO:0004356 (48.3%) GO:0015221 (0.5%) GO:0017089 (0.5%)" "glutamine biosynthetic process (48%) Gram-negative-bacterium-type cell outer membrane assembly (0.5%) isopentenyl diphosphate biosynthetic process (0.2%)" "plasma membrane (0.5%) outer membrane-bounded periplasmic space (0.5%) cytoplasm (0.2%)" "glutamine synthetase activity (48.3%) lipopolysaccharide transmembrane transporter activity (0.5%) glycolipid transfer activity (0.5%)" "IPR022147 (14.3%) IPR052725 (14.3%) IPR008147 (14.2%)" "Glutamine synthetase type III N-terminal (14.3%) Glutamine Synthetase Type-3 (14.3%) Glutamine synthetase, N-terminal domain (14.2%)" LGTAAALSASLPFAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005765 (46.9%) GO:0012505 (2%) GO:0016020 (2%)" GO:0022857 (49%) "lysosomal membrane (46.9%) endomembrane system (2%) membrane (2%)" transmembrane transporter activity (49%) "IPR011701 (25.3%) IPR020846 (25.3%) IPR052187 (25.3%)" "Major facilitator superfamily (25.3%) Major facilitator superfamily domain (25.3%) Lysosomal dipeptide transporter MFSD1 (25.3%)" EDELLLMR root "6.1.1.2 (80%) 2.7.11.1 (20%)" "tryptophan--tRNA ligase (80%) non-specific serine/threonine protein kinase (20%)" "GO:0000076 (4.2%) GO:0006281 (4.2%) GO:0009649 (4.2%)" "GO:0031298 (4.2%) GO:0005829 (3.1%) GO:0016020 (2.1%)" "GO:0000976 (18.8%) GO:0003700 (18.8%) GO:0003677 (4.2%)" "DNA replication checkpoint signaling (4.2%) DNA repair (4.2%) entrainment of circadian clock (4.2%)" "replication fork protection complex (4.2%) cytosol (3.1%) membrane (2.1%)" "transcription cis-regulatory region binding (18.8%) DNA-binding transcription factor activity (18.8%) DNA binding (4.2%)" "IPR000843 (14.9%) IPR025997 (14.9%) IPR010982 (14%)" "LacI-type HTH domain (14.9%) Periplasmic binding protein (14.9%) Lambda repressor-like, DNA-binding domain superfamily (14%)" YAPGVQDEPER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045004 (24.6%) GO:0005829 (24.6%) "GO:0003676 (24.6%) GO:0008408 (24.6%) GO:0004527 (1.8%)" DNA replication proofreading (24.6%) cytosol (24.6%) "nucleic acid binding (24.6%) 3'-5' exonuclease activity (24.6%) exonuclease activity (1.8%)" "IPR046768 (26.3%) IPR012337 (24.6%) IPR013520 (24.6%)" "Exodeoxyribonuclease X-like, C-terminal (26.3%) Ribonuclease H-like superfamily (24.6%) Ribonuclease H-like domain (24.6%)" LNPEAWLSR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0004222 (100%) metalloendopeptidase activity (100%) "IPR016047 (50%) IPR011055 (46.6%) IPR050570 (3.4%)" "M23ase, beta-sheet core domain (50%) Duplicated hybrid motif (46.6%) Bacterial cell wall metabolism enzyme (3.4%)" GLYLETGLLETDYATLQELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0006465 (32.6%) GO:0006508 (1.1%)" GO:0016020 (32.6%) GO:0008236 (33.7%) "signal peptide processing (32.6%) proteolysis (1.1%)" membrane (32.6%) serine-type peptidase activity (33.7%) "IPR002142 (17.1%) IPR047217 (17.1%) IPR004634 (16.6%)" "Peptidase S49 (17.1%) Signal peptide peptidase A, N-terminal (17.1%) Peptidase S49, protease IV (16.6%)" NTLFNGEVTTYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010221 (100%) VCBS domain (100%) LTMLDLPLSGTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (27.3%) IPR025997 (27.3%) IPR010982 (22.7%)" "LacI-type HTH domain (27.3%) Periplasmic binding protein (27.3%) Lambda repressor-like, DNA-binding domain superfamily (22.7%)" LQPGWHVYSTGLGGDGPLSASFNVNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (22.4%) GO:0016020 (2.6%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (22.4%) membrane (2.6%)" protein-disulfide reductase activity (25%) "IPR003834 (25.2%) IPR028250 (25.2%) IPR013766 (24.3%)" "Cytochrome C biogenesis protein, transmembrane domain (25.2%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.2%) Thioredoxin domain (24.3%)" VHCVLDQSLATVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MHDGTNAVADYSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0017004 (33.7%) "GO:0005886 (32.6%) GO:0016020 (1.1%)" GO:0020037 (32.6%) cytochrome complex assembly (33.7%) "plasma membrane (32.6%) membrane (1.1%)" heme binding (32.6%) "IPR007816 (33.7%) IPR002541 (32.6%) IPR045062 (32.6%)" "ResB-like domain (33.7%) Cytochrome c assembly protein (32.6%) Cytochrome c-type biogenesis protein CcsA/CcmC (32.6%)" NLSFSPDGR root 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (26.1%) GO:0000028 (1.4%) GO:0000398 (1.4%)" "GO:0005737 (26.1%) GO:0016020 (2.9%) GO:0005813 (1.4%)" "GO:0008236 (26.1%) GO:0003729 (1.4%)" "proteolysis (26.1%) ribosomal small subunit assembly (1.4%) mRNA splicing, via spliceosome (1.4%)" "cytoplasm (26.1%) membrane (2.9%) centrosome (1.4%)" "serine-type peptidase activity (26.1%) mRNA binding (1.4%)" "IPR011659 (10.9%) IPR005151 (9.8%) IPR012393 (9.8%)" "WD40-like beta-propeller (10.9%) Tail specific protease (9.8%) Tricorn protease (9.8%)" RAPGLYHNTAVVMEK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.5.1.53 (50%) 4.1.3.- (50%)" "N-carbamoylputrescine amidase (50%) Oxo-acid-lyases (50%)" GO:0033388 (41.8%) "GO:0050126 (41.8%) GO:0016746 (15.2%) GO:0016829 (1.3%)" putrescine biosynthetic process from arginine (41.8%) "N-carbamoylputrescine amidase activity (41.8%) acyltransferase activity (15.2%) lyase activity (1.3%)" "IPR003010 (33.7%) IPR050345 (33.7%) IPR036526 (32.7%)" "Carbon-nitrogen hydrolase (33.7%) Aliphatic Amidase/Beta-Ureidopropionase (33.7%) Carbon-nitrogen hydrolase superfamily (32.7%)" TTPYAFYQFWLNVSDDDAEKYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.8%) GO:0005829 (16.8%) "GO:0003723 (16.8%) GO:0004831 (16.8%) GO:0005524 (16.8%)" tyrosyl-tRNA aminoacylation (16.8%) cytosol (16.8%) "RNA binding (16.8%) tyrosine-tRNA ligase activity (16.8%) ATP binding (16.8%)" "IPR002305 (12.6%) IPR002307 (12.6%) IPR014729 (12.6%)" "Aminoacyl-tRNA synthetase, class Ic (12.6%) Tyrosine-tRNA ligase (12.6%) Rossmann-like alpha/beta/alpha sandwich fold (12.6%)" FLAEFLR root "3.5.1.16 (13.1%) 3.4.11.1 (11.5%) 3.4.11.10 (11.5%)" "acetylornithine deacetylase (13.1%) leucyl aminopeptidase (11.5%) bacterial leucyl aminopeptidase (11.5%)" "GO:0051301 (2.8%) GO:0031145 (2.3%) GO:0070979 (2.3%)" "GO:0005886 (5.5%) GO:0005789 (3.5%) GO:0005737 (2.7%)" "GO:0046872 (3.8%) GO:0016787 (2.3%) GO:0016301 (2.2%)" "cell division (2.8%) anaphase-promoting complex-dependent catabolic process (2.3%) protein K11-linked ubiquitination (2.3%)" "plasma membrane (5.5%) endoplasmic reticulum membrane (3.5%) cytoplasm (2.7%)" "metal ion binding (3.8%) hydrolase activity (2.3%) kinase activity (2.2%)" "IPR027417 (3.5%) IPR019164 (2.4%) IPR000515 (1.9%)" "P-loop containing nucleoside triphosphate hydrolase (3.5%) Transmembrane protein 147 (2.4%) ABC transporter type 1, transmembrane domain MetI-like (1.9%)" QDAANDALTQPLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LNGSAYAQFDFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" EYHEALDAAYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) GGAFDENSVYLNNVEVFRPFLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (28.4%) IPR008969 (26.7%) IPR037066 (26.7%)" "TonB-dependent receptor, plug domain (28.4%) Carboxypeptidase-like, regulatory domain superfamily (26.7%) TonB-dependent receptor, plug domain superfamily (26.7%)" KNFEFVLK root 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0055085 (5.7%) GO:0006865 (1.9%) GO:0051301 (1.9%)" "GO:0005886 (16.2%) GO:0016020 (8.6%) GO:0042597 (1%)" "GO:0005524 (23.8%) GO:0016887 (22.9%) GO:0022857 (15.2%)" "transmembrane transport (5.7%) amino acid transport (1.9%) cell division (1.9%)" "plasma membrane (16.2%) membrane (8.6%) periplasmic space (1%)" "ATP binding (23.8%) ATP hydrolysis activity (22.9%) transmembrane transporter activity (15.2%)" "IPR003439 (19.7%) IPR027417 (19.7%) IPR003593 (18.9%)" "ABC transporter-like, ATP-binding domain (19.7%) P-loop containing nucleoside triphosphate hydrolase (19.7%) AAA+ ATPase domain (18.9%)" LLVATDADCNNVTEELSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LWAWNDK root "GO:0019385 (5.6%) GO:0006364 (2.8%) GO:0043041 (2.8%)" "GO:0016020 (47.2%) GO:0005737 (5.6%) GO:0005730 (2.8%)" "GO:0016491 (11.1%) GO:0003723 (2.8%) GO:0016829 (2.8%)" "methanogenesis, from acetate (5.6%) rRNA processing (2.8%) amino acid activation for nonribosomal peptide biosynthetic process (2.8%)" "membrane (47.2%) cytoplasm (5.6%) nucleolus (2.8%)" "oxidoreductase activity (11.1%) RNA binding (2.8%) lyase activity (2.8%)" "IPR015920 (13%) IPR006593 (12%) IPR013783 (12%)" "Cellobiose dehydrogenase-like, cytochrome domain (13%) Cytochrome b561/ferric reductase transmembrane (12%) Immunoglobulin-like fold (12%)" DASATALYGAQGANGVVLLTTK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (3.5%) GO:0009279 (93%) GO:0015344 (3.5%) siderophore transmembrane transport (3.5%) cell outer membrane (93%) siderophore uptake transmembrane transporter activity (3.5%) "IPR023997 (14.5%) IPR037066 (14.5%) IPR039426 (14.5%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (14.5%) TonB-dependent receptor, plug domain superfamily (14.5%) TonB-dependent receptor-like (14.5%)" STTQQYSFNNDLVLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" RVGMPQNNVVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (8.1%) IPR002547 (7.8%) IPR004532 (7.8%)" "Phenylalanyl tRNA synthetase beta chain, core domain (8.1%) tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%)" LLEASPEGVLVVPSSLDVTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (26.3%) IPR025997 (26.3%) IPR010982 (23.7%)" "LacI-type HTH domain (26.3%) Periplasmic binding protein (26.3%) Lambda repressor-like, DNA-binding domain superfamily (23.7%)" LNTADEEEQLNEEDAANPHAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.5%) IPR006512 (25.5%) IPR050144 (25.5%)" "Regulator of K+ conductance, C-terminal (25.5%) YidE/YbjL duplication (25.5%) AAE Transporter (25.5%)" AMLDAEDKSALVDAFYQNLEFGTGGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (15.1%) IPR016066 (15.1%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (15.1%) Alpha-D-phosphohexomutase, conserved site (15.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" SQLVDDLSAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) "GO:0004252 (48.4%) GO:0008239 (1.6%)" proteolysis (50%) "serine-type endopeptidase activity (48.4%) dipeptidyl-peptidase activity (1.6%)" "IPR001375 (34.1%) IPR029058 (33%) IPR011042 (31.9%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.1%) Alpha/Beta hydrolase fold (33%) Six-bladed beta-propeller, TolB-like (31.9%)" VYCGGVDGWGGLGVPQWFGDEFYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (31.1%) IPR012944 (31.1%) IPR033985 (31.1%)" "Tetratricopeptide-like helical domain superfamily (31.1%) RagB/SusD domain (31.1%) SusD-like, N-terminal (31.1%)" LEENGLLYTDGKDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.7%) IPR032790 (20.7%) IPR024742 (20%)" "Glycogen debranching enzyme (20.7%) Glycogen debranching enzyme, C-terminal (20.7%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20%)" LLATRPGHTVNNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.1.108 (57.3%) 4.2.1.59 (42.7%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (57.3%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (42.7%)" "GO:0009245 (14.8%) GO:0006633 (11.9%)" "GO:0016020 (14.8%) GO:0005737 (14.2%)" "GO:0046872 (14.8%) GO:0103117 (14.8%) GO:0016836 (6.3%)" "lipid A biosynthetic process (14.8%) fatty acid biosynthetic process (11.9%)" "membrane (14.8%) cytoplasm (14.2%)" "metal ion binding (14.8%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.8%) hydro-lyase activity (6.3%)" "IPR004463 (15%) IPR013114 (15%) IPR011334 (14.5%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (15%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (15%) UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal (14.5%)" FHFTSTSAAAFAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033985 (55.6%) IPR011990 (44.4%)" "SusD-like, N-terminal (55.6%) Tetratricopeptide-like helical domain superfamily (44.4%)" WQNLPYEEQLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.1.1.190 (80.8%) 2.1.1.- (17.3%) 2.1.1.189 (1.9%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (80.8%) Methyltransferases (17.3%) 23S rRNA (uracil(747)-C(5))-methyltransferase (1.9%)" GO:0070475 (49.6%) GO:0016020 (0.7%) GO:0070041 (49.6%) rRNA base methylation (49.6%) membrane (0.7%) rRNA (uridine-C5-)-methyltransferase activity (49.6%) "IPR010280 (17.5%) IPR030390 (17.2%) IPR030391 (17.2%)" "(Uracil-5)-methyltransferase family (17.5%) RNA methyltransferase TrmA, active site (17.2%) RNA methyltransferase TrmA, conserved site (17.2%)" DLTLSGSNYVAYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.4%) GO:0016787 (48.6%) membrane (51.4%) hydrolase activity (48.6%) "IPR000560 (50.7%) IPR029033 (49.3%)" "Histidine phosphatase superfamily, clade-2 (50.7%) Histidine phosphatase superfamily (49.3%)" GAQATDLALLLLAADDSVMPTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (25%) "GO:0003743 (25%) GO:0003924 (25%) GO:0005525 (25%)" cytoplasm (25%) "translation initiation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (8.6%) IPR005225 (8.6%) IPR006847 (8.6%)" "Translational (tr)-type GTP-binding domain (8.6%) Small GTP-binding domain (8.6%) Translation initiation factor IF-2, N-terminal (8.6%)" VVGGFFEK Pseudomonadati Bacteria Pseudomonadati "GO:0005886 (1.8%) GO:1990281 (1.8%)" "GO:0046872 (47.4%) GO:0051536 (47.4%) GO:0015562 (1.8%)" "plasma membrane (1.8%) efflux pump complex (1.8%)" "metal ion binding (47.4%) iron-sulfur cluster binding (47.4%) efflux transmembrane transporter activity (1.8%)" "IPR017896 (25.4%) IPR017900 (25.4%) IPR047964 (25.4%)" "4Fe-4S ferredoxin-type, iron-sulphur binding domain (25.4%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (25.4%) Polyferredoxin EFR1-like (25.4%)" VYGYDFK root 2.7.7.9 (100%) UTP--glucose-1-phosphate uridylyltransferase (100%) "GO:0009297 (5%) GO:0009306 (5%) GO:0000025 (4.2%)" "GO:0009279 (20.2%) GO:0016020 (12.6%) GO:0015627 (5%)" "GO:0015288 (12.6%) GO:0004556 (4.2%) GO:0004574 (4.2%)" "pilus assembly (5%) protein secretion (5%) maltose catabolic process (4.2%)" "cell outer membrane (20.2%) membrane (12.6%) type II protein secretion system complex (5%)" "porin activity (12.6%) alpha-amylase activity (4.2%) oligo-1,6-glucosidase activity (4.2%)" "IPR005519 (9.7%) IPR006423 (9.7%) IPR023214 (9.7%)" "Acid phosphatase, class B-like (9.7%) 5-nucleotidase lipoprotein e(P4) (9.7%) HAD superfamily (9.7%)" LLEDGDLTMTCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (37.5%) GO:0009341 (12.5%) "GO:0004565 (37.5%) GO:0016787 (12.5%)" carbohydrate metabolic process (37.5%) beta-galactosidase complex (12.5%) "beta-galactosidase activity (37.5%) hydrolase activity (12.5%)" "IPR040719 (33.7%) IPR031330 (31.3%) IPR017853 (30.1%)" "Domain of unknown function DUF5597 (33.7%) Glycoside hydrolase 35, catalytic domain (31.3%) Glycoside hydrolase superfamily (30.1%)" KLQALNDYANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (46.3%) GO:0016020 (3.7%)" GO:0008381 (50%) "plasma membrane (46.3%) membrane (3.7%)" mechanosensitive monoatomic ion channel activity (50%) "IPR006685 (17.3%) IPR045275 (17.3%) IPR049278 (17.3%)" "Mechanosensitive ion channel MscS (17.3%) Mechanosensitive ion channel MscS, archaea/bacteria type (17.3%) Mechanosensitive ion channel MscS, C-terminal domain (17.3%)" ELGDFLFSVLNAAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.1.8 (75.8%) 3.6.1.9 (18.2%) 3.6.1.- (3%)" "ATP diphosphatase (75.8%) nucleotide diphosphatase (18.2%) In phosphorus-containing anhydrides (3%)" "GO:0006203 (13.9%) GO:0046047 (13.9%) GO:0046052 (13.9%)" "GO:0047429 (13.4%) GO:0047693 (0.5%)" "dGTP catabolic process (13.9%) TTP catabolic process (13.9%) UTP catabolic process (13.9%)" "nucleoside triphosphate diphosphatase activity (13.4%) ATP diphosphatase activity (0.5%)" "IPR011551 (25.2%) IPR048011 (25.2%) IPR004518 (24.9%)" "NTP pyrophosphohydrolase MazG (25.2%) MazG-like, C-terminal domain (25.2%) NTP pyrophosphohydrolase MazG-like domain (24.9%)" SLDYVFDGYYSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae YDVDVAR root "2.7.1.23 (20%) 2.7.11.1 (20%) 2.7.8.- (20%)" "NAD(+) kinase (20%) non-specific serine/threonine protein kinase (20%) Transferases for other substituted phosphate groups (20%)" "GO:0006353 (4.9%) GO:0031564 (4.9%) GO:0019350 (2.1%)" "GO:0043190 (14.3%) GO:0016020 (6.7%) GO:0005829 (6.1%)" "GO:0015184 (13.3%) GO:0015276 (11.2%) GO:0003723 (4.9%)" "DNA-templated transcription termination (4.9%) transcription antitermination (4.9%) teichoic acid biosynthetic process (2.1%)" "ATP-binding cassette (ABC) transporter complex (14.3%) membrane (6.7%) cytosol (6.1%)" "L-cystine transmembrane transporter activity (13.3%) ligand-gated monoatomic ion channel activity (11.2%) RNA binding (4.9%)" "IPR001638 (12.5%) IPR018313 (11%) IPR000515 (7.5%)" "Solute-binding protein family 3/N-terminal domain of MltF (12.5%) Solute-binding protein family 3, conserved site (11%) ABC transporter type 1, transmembrane domain MetI-like (7.5%)" SLASLGGFLASDKDTLNFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.47 (100%) 8-amino-7-oxononanoate synthase (100%) "GO:0030170 (50%) GO:0008483 (35.9%) GO:0016740 (12.5%)" "pyridoxal phosphate binding (50%) transaminase activity (35.9%) transferase activity (12.5%)" "IPR001917 (16.9%) IPR004839 (16.9%) IPR050087 (16.9%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.9%) Aminotransferase, class I/classII, large domain (16.9%) 8-amino-7-oxononanoate synthase class-II (16.9%)" VTYLPATTTGAYAHTSTENLVQSGK Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GLADSSELLNFTLQLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.13.- (100%) Dipeptidases (100%) GO:0006508 (49.4%) "GO:0070573 (49.4%) GO:0016740 (1.3%)" proteolysis (49.4%) "metallodipeptidase activity (49.4%) transferase activity (1.3%)" "IPR008257 (25.3%) IPR011697 (25.3%) IPR029062 (24.7%)" "Peptidase M19 (25.3%) Peptidase C26 (25.3%) Class I glutamine amidotransferase-like (24.7%)" VYVMGENLCFWSAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LGQDFQNDGWKE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NYSVAANLSNAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (21.6%) IPR024361 (21.6%) IPR050386 (21.6%)" "Glycoside hydrolase, family 5 (21.6%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.6%) Glycosyl Hydrolase 5 (Cellulase A) (21.6%)" DSFEAATLHVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0008643 (33.3%) GO:0016020 (33.3%) GO:0015288 (33.3%) carbohydrate transport (33.3%) membrane (33.3%) porin activity (33.3%) "IPR007049 (50.7%) IPR038673 (49.3%)" "Carbohydrate-selective porin OprB (50.7%) Carbohydrate-selective porin OprB superfamily (49.3%)" NGLDHEGVLPGPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.3.1.17 (100%) L-serine ammonia-lyase (100%) GO:0006094 (25%) "GO:0003941 (25%) GO:0046872 (25%) GO:0051539 (25%)" gluconeogenesis (25%) "L-serine ammonia-lyase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR005131 (20.8%) IPR051318 (20.8%) IPR004644 (20%)" "Serine dehydratase beta chain (20.8%) Iron-sulphur-dependent L-serine dehydratase (20.8%) Iron-sulphur-dependent L-serine dehydratase single chain form (20%)" YYDVNHDGTLNDADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" LPLNLDSPELSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.6%) IPR008969 (48.4%)" "Family of unknown function DUF5686 (51.6%) Carboxypeptidase-like, regulatory domain superfamily (48.4%)" GDFAVTYHQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.2%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (24.2%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR011110 (12.9%) IPR011123 (12.5%) IPR018060 (12.5%)" "Two component regulator propeller (12.9%) Two component regulator three Y (12.5%) AraC-like, DNA binding HTH domain (12.5%)" ALMPGYHAVHGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (12.8%) IPR002772 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase, family 3, N-terminal (12.8%) Glycoside hydrolase family 3 C-terminal domain (12.8%) Fibronectin type III-like domain (12.8%)" NVTDLVLEGEGETSVLDGQGAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) GO:0005576 (33.3%) GO:0004650 (33.3%) carbohydrate metabolic process (33.3%) extracellular region (33.3%) polygalacturonase activity (33.3%) "IPR000743 (31.6%) IPR011050 (31.6%) IPR012334 (31.6%)" "Glycoside hydrolase, family 28 (31.6%) Pectin lyase fold/virulence factor (31.6%) Pectin lyase fold (31.6%)" KLLVLGADK Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.3.1.180 (97.9%) 7.2.3.1 (2.1%)" "beta-ketoacyl-[acyl-carrier-protein] synthase III (97.9%) Na(+)-exporting diphosphatase (2.1%)" "GO:0006633 (19.5%) GO:0044550 (19.5%) GO:0006814 (0.5%)" "GO:0005737 (19.1%) GO:0005886 (0.5%) GO:0012505 (0.5%)" "GO:0004315 (19.5%) GO:0033818 (19.1%) GO:0000287 (0.5%)" "fatty acid biosynthetic process (19.5%) secondary metabolite biosynthetic process (19.5%) sodium ion transport (0.5%)" "cytoplasm (19.1%) plasma membrane (0.5%) endomembrane system (0.5%)" "3-oxoacyl-[acyl-carrier-protein] synthase activity (19.5%) beta-ketoacyl-acyl-carrier-protein synthase III activity (19.1%) magnesium ion binding (0.5%)" "IPR013747 (24.2%) IPR013751 (24.2%) IPR016039 (24.2%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (24.2%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (24.2%) Thiolase-like (24.2%)" DFPNVVAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25.4%) IPR005263 (25.4%) IPR020625 (25.4%)" "DapA-like (25.4%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25.4%) Schiff base-forming aldolase, active site (25.4%)" KTFDAGFDLSMFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QVLAGVLVTLQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR025393 (51.2%) IPR029044 (48.8%)" "Domain of unknown function DUF4301 (51.2%) Nucleotide-diphospho-sugar transferases (48.8%)" FDNGLNWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (94.7%) GO:0015344 (5.3%) cell outer membrane (94.7%) siderophore uptake transmembrane transporter activity (5.3%) "IPR036942 (94.7%) IPR039426 (5.3%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (94.7%) TonB-dependent receptor-like (5.3%)" FTFNDLK root "2.7.11.1 (94.2%) 1.-.-.- (1.6%) 2.7.4.24 (1.4%)" "non-specific serine/threonine protein kinase (94.2%) Oxidoreductases (1.6%) diphosphoinositol-pentakisphosphate 1-kinase (1.4%)" "GO:0006952 (15%) GO:0051707 (0.8%) GO:0006508 (0.3%)" "GO:0005886 (18%) GO:0016020 (2.3%) GO:0005829 (0.8%)" "GO:0005524 (24.1%) GO:0004674 (20.6%) GO:0004672 (2.3%)" "defense response (15%) response to other organism (0.8%) proteolysis (0.3%)" "plasma membrane (18%) membrane (2.3%) cytosol (0.8%)" "ATP binding (24.1%) protein serine/threonine kinase activity (20.6%) protein kinase activity (2.3%)" "IPR011009 (14.8%) IPR000719 (14.6%) IPR017441 (14.4%)" "Protein kinase-like domain superfamily (14.8%) Protein kinase domain (14.6%) Protein kinase, ATP binding site (14.4%)" TGLCGEHGGEPSSVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (95.9%) 2.7.-.- (4.1%)" "pyruvate, phosphate dikinase (95.9%) Transferring phosphorus-containing groups (4.1%)" "GO:0050242 (25.9%) GO:0005524 (24.7%) GO:0016301 (24.7%)" "pyruvate, phosphate dikinase activity (25.9%) ATP binding (24.7%) kinase activity (24.7%)" "IPR000121 (10.3%) IPR010121 (10.3%) IPR015813 (10.3%)" "PEP-utilising enzyme, C-terminal (10.3%) Pyruvate, phosphate dikinase (10.3%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.3%)" LLSELDPHAFVSQSAVLGVYGEGFDK Pseudomonadati Bacteria Pseudomonadati GO:0005886 (100%) plasma membrane (100%) "IPR015867 (25.5%) IPR019264 (25.5%) IPR051461 (25.5%)" "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25.5%) Domain of unknown function DUF2179 (25.5%) UPF0750 membrane-associated protein (25.5%)" WFDMLGLADKVDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (33.3%) IPR015854 (33.3%) IPR027417 (31.1%)" "ABC transporter-like, ATP-binding domain (33.3%) ABC transporter, lipoprotein release, LolD-like (33.3%) P-loop containing nucleoside triphosphate hydrolase (31.1%)" EFDEETGLYYYGAR Bacteria Bacteria 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (47.3%) GO:0005737 (47.3%)" "GO:0004222 (3.6%) GO:0016787 (1.8%)" "extracellular region (47.3%) cytoplasm (47.3%)" "metalloendopeptidase activity (3.6%) hydrolase activity (1.8%)" "IPR022385 (20.9%) IPR050708 (20.4%) IPR006530 (12.4%)" "Rhs repeat-associated core (20.9%) Type VI secretion system VgrG/RHS (20.4%) YD repeat (12.4%)" TPVTLWR root "2.4.-.- (28.6%) 3.2.1.22 (28.6%) 1.13.12.7 (14.3%)" "Glycosyltransferases (28.6%) alpha-galactosidase (28.6%) firefly luciferase (14.3%)" "GO:0005975 (10.5%) GO:0098542 (9.5%) GO:0006508 (1.9%)" "GO:0016020 (13.3%) GO:0005886 (1.9%) GO:0005829 (1%)" "GO:0004553 (10.5%) GO:0005524 (10.5%) GO:0030246 (9.5%)" "carbohydrate metabolic process (10.5%) defense response to other organism (9.5%) proteolysis (1.9%)" "membrane (13.3%) plasma membrane (1.9%) cytosol (1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (10.5%) ATP binding (10.5%) carbohydrate binding (9.5%)" "IPR006710 (6.2%) IPR013320 (6.2%) IPR016828 (6.2%)" "Glycoside hydrolase, family 43 (6.2%) Concanavalin A-like lectin/glucanase domain superfamily (6.2%) Alpha-L-arabinofuranosidase (6.2%)" RGMVVVHPGALTPHDHFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.6%) GO:0032045 (13.7%)" "GO:0003746 (14.6%) GO:0005525 (14.6%) GO:0003924 (14%)" "cytosol (14.6%) guanyl-nucleotide exchange factor complex (13.7%)" "translation elongation factor activity (14.6%) GTP binding (14.6%) GTPase activity (14%)" "IPR004160 (8.5%) IPR004161 (8.5%) IPR009000 (8.5%)" "Translation elongation factor EFTu/EF1A, C-terminal (8.5%) Translation elongation factor EFTu-like, domain 2 (8.5%) Translation protein, beta-barrel domain superfamily (8.5%)" YGSFDQLAENNNKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20%) IPR008753 (20%) IPR018497 (20%)" "Peptidase M13 (20%) Peptidase M13, N-terminal domain (20%) Peptidase M13, C-terminal domain (20%)" KQVALLVDEWGTWWDEEPGTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (26.7%) IPR013780 (24.4%) IPR017853 (24.4%)" "Alpha-L-arabinofuranosidase, C-terminal (26.7%) Glycosyl hydrolase, all-beta (24.4%) Glycoside hydrolase superfamily (24.4%)" VSAEFVAAADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002880 (7.9%) IPR011766 (7.9%) IPR011895 (7.9%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.9%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Pyruvate-flavodoxin oxidoreductase (7.9%)" VVLRPEAQLQEVVVTGLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QVNFLDKNNDQNYYFAAPLPSAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR011050 (51.7%) IPR012334 (48.3%)" "Pectin lyase fold/virulence factor (51.7%) Pectin lyase fold (48.3%)" HHFDELEVLDLVDCNAGNHHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.5.1.7 (100%) saccharopine dehydrogenase (NAD(+), L-lysine-forming) (100%) GO:0004754 (100%) saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (100%) "IPR005097 (33.3%) IPR032095 (33.3%) IPR036291 (33.3%)" "Saccharopine dehydrogenase, NADP binding domain (33.3%) Saccharopine dehydrogenase-like, C-terminal (33.3%) NAD(P)-binding domain superfamily (33.3%)" EAAAELKPLLAACAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006979 (14.9%) GO:0022900 (13.9%) GO:0044281 (13.9%)" "GO:0030976 (14.9%) GO:0005506 (13.9%) GO:0016903 (13.9%)" "response to oxidative stress (14.9%) electron transport chain (13.9%) small molecule metabolic process (13.9%)" "thiamine pyrophosphate binding (14.9%) iron ion binding (13.9%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (13.9%)" "IPR011766 (8.3%) IPR050722 (8.3%) IPR002880 (7.8%)" "Thiamine pyrophosphate enzyme, TPP-binding (8.3%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.3%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%)" KYNLFVK root "7.2.2.14 (42.4%) 2.7.11.1 (21.2%) 1.2.7.3 (9.1%)" "P-type Mg(2+) transporter (42.4%) non-specific serine/threonine protein kinase (21.2%) 2-oxoglutarate synthase (9.1%)" "GO:0044718 (7.4%) GO:0000724 (1.5%) GO:0000077 (1.3%)" "GO:0009279 (7.4%) GO:0005886 (4.1%) GO:0016020 (4.1%)" "GO:0015344 (7.4%) GO:0005524 (4.5%) GO:0046872 (3.2%)" "siderophore transmembrane transport (7.4%) double-strand break repair via homologous recombination (1.5%) DNA damage checkpoint signaling (1.3%)" "cell outer membrane (7.4%) plasma membrane (4.1%) membrane (4.1%)" "siderophore uptake transmembrane transporter activity (7.4%) ATP binding (4.5%) metal ion binding (3.2%)" "IPR000531 (5.8%) IPR012910 (5.8%) IPR039426 (5.8%)" "TonB-dependent receptor-like, beta-barrel (5.8%) TonB-dependent receptor, plug domain (5.8%) TonB-dependent receptor-like (5.8%)" TLPNLCFYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10%) IPR003593 (10%) IPR003959 (10%)" "Peptidase M41 (10%) AAA+ ATPase domain (10%) ATPase, AAA-type, core (10%)" TTDWQLSYDGR Bacteroidota Bacteria Pseudomonadati Bacteroidota "5.99.1.- (53.8%) 5.99.1.3 (30.8%) 5.6.2.2 (15.4%)" "Other isomerases (53.8%) Transferred entry: 5.6.2.2 (30.8%) DNA topoisomerase (ATP-hydrolyzing) (15.4%)" GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.5%) IPR050220 (20.5%) IPR013758 (19.7%)" "DNA topoisomerase, type IIA, domain A (20.5%) Type II DNA Topoisomerases (20.5%) DNA topoisomerase, type IIA, domain A, alpha-beta (19.7%)" QLGQLEMQDQMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (80%) 3.4.14.12 (20%)" "Acting on peptide bonds (peptidases) (80%) Xaa-Xaa-Pro tripeptidyl-peptidase (20%)" GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" VGRSMGMPEHLLTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.9%) "GO:0003921 (32.9%) GO:0005524 (32.9%) GO:0016740 (1.3%)" cytosol (32.9%) "GMP synthase activity (32.9%) ATP binding (32.9%) transferase activity (1.3%)" "IPR001674 (13%) IPR025777 (13%) IPR004739 (12.4%)" "GMP synthase, C-terminal (13%) GMP synthetase ATP pyrophosphatase domain (13%) GMP synthase, glutamine amidotransferase (12.4%)" VLGQDEALTAVSDAVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0034605 (19.8%) GO:0042026 (18.7%) GO:0006508 (1.1%)" GO:0005737 (19.8%) "GO:0005524 (19.8%) GO:0016887 (19.8%) GO:0008233 (1.1%)" "cellular response to heat (19.8%) protein refolding (18.7%) proteolysis (1.1%)" cytoplasm (19.8%) "ATP binding (19.8%) ATP hydrolysis activity (19.8%) peptidase activity (1.1%)" "IPR003593 (8.6%) IPR003959 (8.6%) IPR050130 (8.6%)" "AAA+ ATPase domain (8.6%) ATPase, AAA-type, core (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%)" FGLYADTYNDANAVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LALLTGATSGLGEGCAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" LAMVLNLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR032276 (100%) Protein of unknown function DUF4836 (100%) ELHFLHAQDLLDMYPDLSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (22.5%) GO:0006529 (2.5%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (22.5%) GO:0000166 (2.5%)" "L-asparagine biosynthetic process (22.5%) obsolete asparagine biosynthetic process (2.5%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (22.5%) nucleotide binding (2.5%)" "IPR004618 (34.5%) IPR006195 (34.5%) IPR045864 (31%)" "Aspartate--ammonia ligase (34.5%) Aminoacyl-tRNA synthetase, class II (34.5%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (31%)" LDAMAGSSWTQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" VTQGTVTDFDGNFSLNVKPGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" GMNQLYQESGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) GLLPLLSK root "7.1.1.2 (28.1%) 1.11.1.7 (7%) 1.4.1.13 (7%)" "NADH:ubiquinone reductase (H(+)-translocating) (28.1%) peroxidase (7%) glutamate synthase (NADPH) (7%)" "GO:0006366 (4.1%) GO:0006284 (2.2%) GO:0006120 (1.7%)" "GO:0005886 (5.4%) GO:0005665 (4.1%) GO:0016020 (2.9%)" "GO:0003677 (5.9%) GO:0003899 (4.1%) GO:0046983 (4.1%)" "transcription by RNA polymerase II (4.1%) base-excision repair (2.2%) mitochondrial electron transport, NADH to ubiquinone (1.7%)" "plasma membrane (5.4%) RNA polymerase II, core complex (4.1%) membrane (2.9%)" "DNA binding (5.9%) DNA-directed RNA polymerase activity (4.1%) protein dimerization activity (4.1%)" "IPR011262 (3.1%) IPR011263 (3.1%) IPR022842 (3.1%)" "DNA-directed RNA polymerase, insert domain (3.1%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (3.1%) DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1 (3.1%)" FDTQDLASVLAQLSNNQQFSTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR043864 (27.6%) IPR016035 (25.2%) IPR002641 (23.6%)" "OMP85-like, membrane spanning beta-barrel domain (27.6%) Acyl transferase/acyl hydrolase/lysophospholipase (25.2%) Patatin-like phospholipase domain (23.6%)" NVLDNVMQYLQTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (32.7%) GO:0016020 (34.6%) GO:0003677 (32.7%) regulation of DNA-templated transcription (32.7%) membrane (34.6%) DNA binding (32.7%) "IPR016032 (47.2%) IPR036388 (47.2%) IPR000792 (5.6%)" "Signal transduction response regulator, C-terminal effector (47.2%) Winged helix-like DNA-binding domain superfamily (47.2%) Transcription regulator LuxR, C-terminal (5.6%)" ALVEVVDKGWVPAPGLQPVNATLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032342 (100%) Protein of unknown function DUF4861 (100%) ASYQLVLPEGTFHYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) DEATGLVTFDYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) IPR008757 (100%) Peptidase M6-like, domain (100%) NYVEKDQFEDAPVNYEDALENYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016627 (50%) GO:0050660 (50%)" "oxidoreductase activity, acting on the CH-CH group of donors (50%) flavin adenine dinucleotide binding (50%)" "IPR006091 (10%) IPR009075 (10%) IPR009100 (10%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (10%) Acyl-CoA dehydrogenase/oxidase, C-terminal (10%) Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily (10%)" AVLEEVKGHAELL Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (20%) GO:0005737 (20%) "GO:0003746 (20%) GO:0003924 (20%) GO:0005525 (20%)" ribosome disassembly (20%) cytoplasm (20%) "translation elongation factor activity (20%) GTPase activity (20%) GTP binding (20%)" "IPR000640 (6.4%) IPR000795 (6.4%) IPR004161 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translational (tr)-type GTP-binding domain (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%)" YPDAWLLLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (14.3%) GO:0042834 (85.7%) cell division (14.3%) peptidoglycan binding (85.7%) "IPR007730 (50%) IPR036680 (50%)" "Sporulation-like domain (50%) Sporulation-like domain superfamily (50%)" LVYVYAQDFTVNGGSLSETMAQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.-.-.- (100%) Ligases (100%) "GO:0015977 (21.1%) GO:0006633 (8.3%)" GO:0009317 (21.1%) "GO:0004658 (21.5%) GO:0003989 (21.1%) GO:0016740 (5.4%)" "carbon fixation (21.1%) fatty acid biosynthetic process (8.3%)" acetyl-CoA carboxylase complex (21.1%) "propionyl-CoA carboxylase activity (21.5%) acetyl-CoA carboxylase activity (21.1%) transferase activity (5.4%)" "IPR011762 (18.7%) IPR011763 (18.7%) IPR034733 (18.7%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.7%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.7%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.7%)" NGTANLTMNVENPHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25%) GO:0009341 (25%) "GO:0004565 (25%) GO:0030246 (25%)" lactose catabolic process (25%) beta-galactosidase complex (25%) "beta-galactosidase activity (25%) carbohydrate binding (25%)" "IPR004199 (7.1%) IPR006101 (7.1%) IPR006102 (7.1%)" "Beta galactosidase small chain/ domain 5 (7.1%) Glycoside hydrolase, family 2 (7.1%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.1%)" NLTSSELSNGYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.6%) GO:0006526 (13.5%) GO:0006221 (12.9%)" GO:0005737 (14.6%) "GO:0004088 (14.6%) GO:0005524 (14.6%) GO:0046872 (13.5%)" "glutamine metabolic process (14.6%) L-arginine biosynthetic process (13.5%) pyrimidine nucleotide biosynthetic process (12.9%)" cytoplasm (14.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.6%) ATP binding (14.6%) metal ion binding (13.5%)" "IPR011607 (11%) IPR036914 (11%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (11%) Methylglyoxal synthase-like domain superfamily (11%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" TLMDELDWSDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR041682 (36.2%) IPR027417 (34.8%) IPR036390 (29%)" "AAA domain, group 14 (36.2%) P-loop containing nucleoside triphosphate hydrolase (34.8%) Winged helix DNA-binding domain superfamily (29%)" KEGLLPCNLYGEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" FLLEDLDKAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR033985 (33.3%) IPR012944 (16.7%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (33.3%) RagB/SusD domain (16.7%)" MSELKDYTLELGPELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR013096 (25.8%) IPR051610 (25.8%) IPR011051 (24.2%)" "Cupin 2, conserved barrel (25.8%) Glucose-6-phosphate isomerase/Oxalate decarboxylase (25.8%) RmlC-like cupin domain superfamily (24.2%)" GQVAELSVQLAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (18.6%) GO:0012505 (18.6%) GO:0045259 (18.6%)" "GO:0046933 (18.6%) GO:0046961 (18.6%) GO:0016787 (6.8%)" "plasma membrane (18.6%) endomembrane system (18.6%) proton-transporting ATP synthase complex (18.6%)" "proton-transporting ATP synthase activity, rotational mechanism (18.6%) proton-transporting ATPase activity, rotational mechanism (18.6%) hydrolase activity (6.8%)" "IPR002146 (25.6%) IPR005864 (25.6%) IPR050059 (25.6%)" "ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast (25.6%) ATP synthase, F0 complex, subunit b, bacterial (25.6%) ATP synthase B chain (25.6%)" QGQVWLR root "2.7.13.3 (88.9%) 7.6.2.1 (11.1%)" "histidine kinase (88.9%) P-type phospholipid transporter (11.1%)" "GO:0006412 (18.1%) GO:0006260 (0.2%) GO:0006631 (0.2%)" "GO:0022625 (18.1%) GO:0016020 (2.3%) GO:0005886 (0.5%)" "GO:0003735 (18.1%) GO:0019843 (18.1%) GO:0000049 (16.9%)" "translation (18.1%) DNA replication (0.2%) fatty acid metabolic process (0.2%)" "cytosolic large ribosomal subunit (18.1%) membrane (2.3%) plasma membrane (0.5%)" "structural constituent of ribosome (18.1%) rRNA binding (18.1%) tRNA binding (16.9%)" "IPR000114 (15.5%) IPR016180 (15.5%) IPR020798 (15.5%)" "Large ribosomal subunit protein uL16, bacteria (15.5%) Large ribosomal subunit protein uL16 domain (15.5%) Large ribosomal subunit protein uL16, conserved site (15.5%)" DGKDLLSDFSVLNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.7%) IPR029483 (14.7%) IPR029486 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%)" LSSMGASLSDLLPEFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0140359 (50%) plasma membrane (50%) ABC-type transporter activity (50%) "IPR013525 (50%) IPR051449 (50%)" "ABC-2 type transporter, transmembrane domain (50%) ABC-2 integral membrane transporter component (50%)" FTTTFSPNYSHKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" NDQLLVQPQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17.9%) GO:0045259 (17.9%)" "GO:0005524 (17.9%) GO:0043531 (17.9%) GO:0046933 (17.9%)" "plasma membrane (17.9%) proton-transporting ATP synthase complex (17.9%)" "ATP binding (17.9%) ADP binding (17.9%) proton-transporting ATP synthase activity, rotational mechanism (17.9%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" ANHQLVVTLEDGSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.7 (100%) 1-deoxy-D-xylulose-5-phosphate synthase (100%) "GO:0016114 (16.3%) GO:0019288 (16.3%) GO:0009228 (14.9%)" GO:0005829 (16.3%) "GO:0008661 (16.3%) GO:0046872 (14.9%)" "terpenoid biosynthetic process (16.3%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (16.3%) thiamine biosynthetic process (14.9%)" cytosol (16.3%) "1-deoxy-D-xylulose-5-phosphate synthase activity (16.3%) metal ion binding (14.9%)" "IPR005475 (17.2%) IPR005477 (17.2%) IPR033248 (17.2%)" "Transketolase-like, pyrimidine-binding domain (17.2%) Deoxyxylulose-5-phosphate synthase (17.2%) Transketolase, C-terminal domain (17.2%)" SLGLTLGAYYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) DTEKLELTDDVYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" QLYSLDMGALVAGAK root "GO:0034605 (18.8%) GO:0042026 (18.2%) GO:0006508 (2.7%)" "GO:0005737 (18.8%) GO:0005829 (0.2%)" "GO:0005524 (18.9%) GO:0016887 (18.9%) GO:0008233 (2.7%)" "cellular response to heat (18.8%) protein refolding (18.2%) proteolysis (2.7%)" "cytoplasm (18.8%) cytosol (0.2%)" "ATP binding (18.9%) ATP hydrolysis activity (18.9%) peptidase activity (2.7%)" "IPR003593 (8.4%) IPR003959 (8.4%) IPR018368 (8.4%)" "AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%) ClpA/B, conserved site 1 (8.4%)" LAAGAELTK root "GO:0030261 (13%) GO:0006270 (4.3%) GO:0006351 (4.3%)" "GO:0005829 (13%) GO:0016020 (4.3%) GO:1990103 (4.3%)" "GO:0003677 (13%) GO:0030527 (13%) GO:0000976 (4.3%)" "chromosome condensation (13%) DNA replication initiation (4.3%) DNA-templated transcription (4.3%)" "cytosol (13%) membrane (4.3%) DnaA-HU complex (4.3%)" "DNA binding (13%) structural constituent of chromatin (13%) transcription cis-regulatory region binding (4.3%)" "IPR000119 (14.3%) IPR010992 (14.3%) IPR020816 (14.3%)" "Histone-like DNA-binding protein (14.3%) Integration host factor (IHF)-like DNA-binding domain superfamily (14.3%) Histone-like DNA-binding protein, conserved site (14.3%)" ENEEGYKVNPLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" QVFSTLENQTSYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.5%) IPR012910 (13.5%) IPR023996 (13.5%)" "Carboxypeptidase-like, regulatory domain superfamily (13.5%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%)" RGYLALDNFDYGSLFNTSFPMNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.3%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.3%)" SPLYNNDGYLDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR026950 (50%) IPR038636 (50%)" "Capsule assembly protein Wzi (50%) Capsule assembly protein Wzi superfamily (50%)" FGTEYLVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004386 (100%) helicase activity (100%) "IPR024450 (41.5%) IPR007936 (38.5%) IPR014907 (20%)" "Domain of unknown function DUF3874 (41.5%) Virulence-associated protein E-like domain (38.5%) BT4734-like, N-terminal (20%)" GGASVPLAQNQQAMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) MLNLSEVLETNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) YGGPDRDHQLEVYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.8 (100%) mannonate dehydratase (100%) GO:0042840 (25%) "GO:0008198 (25%) GO:0008927 (25%) GO:0030145 (25%)" D-glucuronate catabolic process (25%) "ferrous iron binding (25%) mannonate dehydratase activity (25%) manganese ion binding (25%)" "IPR004628 (51%) IPR036237 (49%)" "Mannonate dehydratase (51%) Xylose isomerase-like superfamily (49%)" KVVNSSLLK root "GO:0044718 (25.9%) GO:0006357 (3.7%)" "GO:0009279 (29.6%) GO:0005634 (3.7%)" "GO:0015344 (25.9%) GO:0008270 (7.4%) GO:0003712 (3.7%)" "siderophore transmembrane transport (25.9%) regulation of transcription by RNA polymerase II (3.7%)" "cell outer membrane (29.6%) nucleus (3.7%)" "siderophore uptake transmembrane transporter activity (25.9%) zinc ion binding (7.4%) transcription coregulator activity (3.7%)" "IPR057601 (21.1%) IPR036942 (18.4%) IPR039426 (18.4%)" "TonB-dependent transporter Oar-like, beta-barrel domain (21.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (18.4%) TonB-dependent receptor-like (18.4%)" TCDYPVNGEPNSQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" KGNLSLQLSPSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (26.6%) GO:0030203 (23.4%)" GO:0016020 (23.4%) "GO:0004563 (23.4%) GO:0016798 (3.2%)" "carbohydrate metabolic process (26.6%) glycosaminoglycan metabolic process (23.4%)" membrane (23.4%) "beta-N-acetylhexosaminidase activity (23.4%) hydrolase activity, acting on glycosyl bonds (3.2%)" "IPR015882 (18.4%) IPR029018 (17.6%) IPR011658 (16.2%)" "Beta-hexosaminidase, bacterial type, N-terminal (18.4%) Beta-hexosaminidase-like, domain 2 (17.6%) PA14 domain (16.2%)" ELDADLLK root "2.7.1.36 (48%) 4.2.3.4 (10%) 2.7.1.4 (6%)" "mevalonate kinase (48%) 3-dehydroquinate synthase (10%) fructokinase (6%)" "GO:0006529 (5.4%) GO:0006695 (4.2%) GO:0019287 (4.2%)" "GO:0005829 (6.6%) GO:0005737 (2.6%) GO:0016020 (1.4%)" "GO:0005524 (7%) GO:0004066 (5.4%) GO:0046872 (5.2%)" "obsolete asparagine biosynthetic process (5.4%) cholesterol biosynthetic process (4.2%) isopentenyl diphosphate biosynthetic process, mevalonate pathway (4.2%)" "cytosol (6.6%) cytoplasm (2.6%) membrane (1.4%)" "ATP binding (7%) asparagine synthase (glutamine-hydrolyzing) activity (5.4%) metal ion binding (5.2%)" "IPR014729 (4.2%) IPR001962 (3.9%) IPR051857 (3.8%)" "Rossmann-like alpha/beta/alpha sandwich fold (4.2%) Asparagine synthase (3.9%) Asparagine synthetase domain-containing protein (3.8%)" EYHLACNDGPNHLHGGPTGFHTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20%) GO:0033499 (20%)" GO:0005737 (20%) "GO:0004034 (20%) GO:0030246 (20%)" "glucose metabolic process (20%) galactose catabolic process via UDP-galactose, Leloir pathway (20%)" cytoplasm (20%) "aldose 1-epimerase activity (20%) carbohydrate binding (20%)" "IPR008183 (20%) IPR011013 (20%) IPR014718 (20%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (20%) Galactose mutarotase-like domain superfamily (20%) Glycoside hydrolase-type carbohydrate-binding (20%)" DAVLQTADGDFHQFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" KMFQDMVDNLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003593 (25%) IPR003959 (25%) IPR027417 (25%)" "AAA+ ATPase domain (25%) ATPase, AAA-type, core (25%) P-loop containing nucleoside triphosphate hydrolase (25%)" CSFVCPHAALR root "1.2.7.1 (79.8%) 1.2.7.- (13.3%) 1.2.1.51 (6.9%)" "pyruvate synthase (79.8%) With an iron-sulfur protein as acceptor (13.3%) pyruvate dehydrogenase (NADP(+)) (6.9%)" "GO:0006979 (16.3%) GO:0022900 (16.2%) GO:0044281 (3.1%)" GO:0005737 (0%) "GO:0005506 (16.2%) GO:0051539 (16.2%) GO:0030976 (15.5%)" "response to oxidative stress (16.3%) electron transport chain (16.2%) small molecule metabolic process (3.1%)" cytoplasm (0%) "iron ion binding (16.2%) 4 iron, 4 sulfur cluster binding (16.2%) thiamine pyrophosphate binding (15.5%)" "IPR017896 (8%) IPR017900 (8%) IPR050722 (8%)" "4Fe-4S ferredoxin-type, iron-sulphur binding domain (8%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (8%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8%)" YACVSLTGCEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002547 (7.8%) IPR004532 (7.8%) IPR005121 (7.8%)" "tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%) Ferrodoxin-fold anticodon-binding domain (7.8%)" VSEDLEFYSVMR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (32.5%) "GO:0005525 (32.5%) GO:0043022 (32.5%) GO:0016787 (2.6%)" ribosome biogenesis (32.5%) "GTP binding (32.5%) ribosome binding (32.5%) hydrolase activity (2.6%)" "IPR005225 (14.3%) IPR006073 (14.3%) IPR016484 (14.3%)" "Small GTP-binding domain (14.3%) GTP binding domain (14.3%) GTPase Der (14.3%)" FLVPETK root "3.4.-.- (46.6%) 2.7.7.87 (13.8%) 2.3.2.27 (8.6%)" "Acting on peptide bonds (peptidases) (46.6%) L-threonylcarbamoyladenylate synthase (13.8%) RING-type E3 ubiquitin transferase (8.6%)" "GO:0046323 (3.2%) GO:0070837 (3.2%) GO:1990539 (2.7%)" "GO:0016020 (24.2%) GO:0005886 (6.9%) GO:0042383 (2.6%)" "GO:0005351 (14.1%) GO:0022857 (7%) GO:0055056 (3.5%)" "D-glucose import (3.2%) dehydroascorbic acid transport (3.2%) fructose import across plasma membrane (2.7%)" "membrane (24.2%) plasma membrane (6.9%) sarcolemma (2.6%)" "carbohydrate:proton symporter activity (14.1%) transmembrane transporter activity (7%) D-glucose transmembrane transporter activity (3.5%)" "IPR005828 (16.6%) IPR036259 (16.6%) IPR020846 (16.5%)" "Major facilitator, sugar transporter-like (16.6%) MFS transporter superfamily (16.6%) Major facilitator superfamily domain (16.5%)" DLGVVLVTSLFER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033388 (42%) "GO:0050126 (42%) GO:0016746 (16%)" putrescine biosynthetic process from arginine (42%) "N-carbamoylputrescine amidase activity (42%) acyltransferase activity (16%)" "IPR003010 (33.7%) IPR050345 (33.7%) IPR036526 (32.7%)" "Carbon-nitrogen hydrolase (33.7%) Aliphatic Amidase/Beta-Ureidopropionase (33.7%) Carbon-nitrogen hydrolase superfamily (32.7%)" NLLQNYQLYNEMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (20%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (20%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (20%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (20%)" "IPR000489 (25.3%) IPR006390 (25.3%) IPR045031 (25.3%)" "Pterin-binding domain (25.3%) Dihydropteroate synthase domain (25.3%) Dihydropteroate synthase-like (25.3%)" TVDHYGETYSSSTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" TPYSQASQLNYDSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" DHYATVTFSNTGDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.7%) IPR013148 (14.7%) IPR018053 (14.7%)" "Glycoside hydrolase, family 32 (14.7%) Glycosyl hydrolase family 32, N-terminal (14.7%) Glycoside hydrolase, family 32, active site (14.7%)" MVTLTFGK Bacteria Bacteria "3.6.4.13 (95.8%) 3.6.4.- (4.2%)" "RNA helicase (95.8%) Acting on ATP; involved in cellular and subcellular movement (4.2%)" GO:0032259 (0.5%) GO:0005829 (9.9%) "GO:0003724 (22%) GO:0005524 (22%) GO:0016787 (22%)" methylation (0.5%) cytosol (9.9%) "RNA helicase activity (22%) ATP binding (22%) hydrolase activity (22%)" "IPR000629 (10.1%) IPR001650 (10.1%) IPR005580 (10.1%)" "ATP-dependent RNA helicase DEAD-box, conserved site (10.1%) Helicase, C-terminal domain-like (10.1%) DEAD box helicase DbpA/CsdA, RNA-binding domain (10.1%)" DVMTADMPVYNADYDYFSSLENGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GYASPEGSKELNQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006811 (23.8%) "GO:0009279 (28.6%) GO:0046930 (23.8%)" GO:0015288 (23.8%) monoatomic ion transport (23.8%) "cell outer membrane (28.6%) pore complex (23.8%)" porin activity (23.8%) "IPR006664 (20.5%) IPR006665 (20.5%) IPR036737 (20.5%)" "Outer membrane protein, bacterial (20.5%) OmpA-like domain (20.5%) OmpA-like domain superfamily (20.5%)" LEDDVLLTK root "3.4.13.9 (51.7%) 3.4.11.9 (42.4%) 3.4.-.- (2.3%)" "Xaa-Pro dipeptidase (51.7%) Xaa-Pro aminopeptidase (42.4%) Acting on peptide bonds (peptidases) (2.3%)" "GO:0006508 (11.7%) GO:0045893 (1.9%) GO:0044528 (1.3%)" "GO:0005829 (6.9%) GO:0035097 (1.9%) GO:0005739 (1.6%)" "GO:0030145 (18.5%) GO:0070006 (18.5%) GO:0016805 (8.3%)" "proteolysis (11.7%) positive regulation of DNA-templated transcription (1.9%) regulation of mitochondrial mRNA stability (1.3%)" "cytosol (6.9%) histone methyltransferase complex (1.9%) mitochondrion (1.6%)" "manganese ion binding (18.5%) metalloaminopeptidase activity (18.5%) dipeptidase activity (8.3%)" "IPR000994 (15.9%) IPR036005 (15.7%) IPR029149 (14.3%)" "Peptidase M24 (15.9%) Creatinase/aminopeptidase-like (15.7%) Creatinase/Aminopeptidase P/Spt16, N-terminal (14.3%)" ALLENLTELESATGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YLLVVEK root "5.6.2.2 (77.3%) 5.4.99.- (17.2%) 2.7.13.3 (2.4%)" "DNA topoisomerase (ATP-hydrolyzing) (77.3%) Transferring other groups (17.2%) histidine kinase (2.4%)" "GO:0042138 (9.9%) GO:0000706 (9.4%) GO:0007131 (8.9%)" "GO:0000228 (9.4%) GO:0005694 (1.2%) GO:0016020 (0.9%)" "GO:0003677 (10.7%) GO:0003918 (10.6%) GO:0005524 (9.6%)" "meiotic DNA double-strand break formation (9.9%) meiotic DNA double-strand break processing (9.4%) reciprocal meiotic recombination (8.9%)" "nuclear chromosome (9.4%) chromosome (1.2%) membrane (0.9%)" "DNA binding (10.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (10.6%) ATP binding (9.6%)" "IPR002815 (13.7%) IPR034136 (13.6%) IPR036078 (13.6%)" "Spo11/DNA topoisomerase VI subunit A (13.7%) Topoisomerase 6 subunit A/Spo11, TOPRIM domain (13.6%) Spo11/DNA topoisomerase VI subunit A superfamily (13.6%)" LYNTELGLSDNSVASLLEDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (1.2%) "GO:0000155 (24.7%) GO:0003700 (24.7%) GO:0005524 (24.7%)" membrane (1.2%) "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (24.7%) ATP binding (24.7%)" "IPR001789 (7.5%) IPR003594 (7.5%) IPR003661 (7.5%)" "Signal transduction response regulator, receiver domain (7.5%) Histidine kinase/HSP90-like ATPase domain (7.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.5%)" VLEDAEANTAETLKPLLAELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (24.6%) GO:0016887 (24.6%) GO:0051082 (24.6%)" "ATP binding (24.6%) ATP hydrolysis activity (24.6%) unfolded protein binding (24.6%)" "IPR001404 (20%) IPR019805 (20%) IPR020568 (20%)" "Heat shock protein Hsp90 family (20%) Heat shock protein Hsp90, conserved site (20%) Ribosomal protein uS5 domain 2-type superfamily (20%)" YLQHTMEDAQFFNNQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) LNAELEEVLEDLTNTANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015920 (50%) GO:0043190 (50%) lipopolysaccharide transport (50%) ATP-binding cassette (ABC) transporter complex (50%) IPR005495 (100%) Permease LptG/LptF-related (100%) LNGDYLWTGGFSGDYLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" DYQDLHGGTTTGYYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" HTDYYLQSMLYSLLVSHNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011604 (33.3%) IPR027417 (33.3%) IPR038726 (33.3%)" "PD-(D/E)XK endonuclease-like domain superfamily (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) PD-(D/E)XK endonuclease-like domain, AddAB-type (33.3%)" WETQATLQHNSNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TDADGNVSLVSYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (50%) GO:1990351 (50%)" "cell outer membrane (50%) transporter complex (50%)" "IPR045659 (50%) IPR050218 (50%)" "LPS-assembly protein LptD, central domain (50%) Lipopolysaccharide Assembly Protein LptD (50%)" AGNLLAANYVLSHLGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071555 (25.5%) GO:0005886 (25.5%) "GO:0008658 (25.5%) GO:0004180 (23.6%)" cell wall organization (25.5%) plasma membrane (25.5%) "penicillin binding (25.5%) carboxypeptidase activity (23.6%)" "IPR001460 (17.1%) IPR005543 (17.1%) IPR050515 (17.1%)" "Penicillin-binding protein, transpeptidase (17.1%) PASTA domain (17.1%) Class D beta-lactamase/transpeptidase (17.1%)" TLGNDWEELFVNMNDGSNEGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006207 (15.9%) GO:0006526 (15.9%) GO:0006541 (15.9%)" "GO:0004088 (15.9%) GO:0005524 (15.9%) GO:0004359 (4.3%)" "'de novo' pyrimidine nucleobase biosynthetic process (15.9%) L-arginine biosynthetic process (15.9%) glutamine metabolic process (15.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (15.9%) ATP binding (15.9%) glutaminase activity (4.3%)" "IPR002474 (14.3%) IPR006274 (14.3%) IPR017926 (14.3%)" "Carbamoyl-phosphate synthase small subunit, N-terminal domain (14.3%) Carbamoyl-phosphate synthase, small subunit (14.3%) Glutamine amidotransferase (14.3%)" GGWYGSPFTLGVNLTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.6%) IPR023996 (34.6%) IPR037066 (30.8%)" "TonB-dependent receptor, plug domain (34.6%) TonB-dependent outer membrane protein, SusC/RagA (34.6%) TonB-dependent receptor, plug domain superfamily (30.8%)" TYKGDNLQAELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003959 (50%) IPR027417 (50%)" "ATPase, AAA-type, core (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" NVPLCDVLDVHLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) LDDPALFEDVPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.3 (100%) phosphoribosylaminoimidazolecarboxamide formyltransferase (100%) GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (26.8%) IPR016193 (25%) IPR024051 (25%)" "Bifunctional purine biosynthesis protein PurH-like (26.8%) Cytidine deaminase-like (25%) AICAR transformylase, duplicated domain superfamily (25%)" TDKPLLYYPLDSWFLK root 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (15%) "GO:0005737 (13.7%) GO:0016020 (0%)" "GO:0004822 (15%) GO:0005524 (15%) GO:0000049 (13.8%)" isoleucyl-tRNA aminoacylation (15%) "cytoplasm (13.7%) membrane (0%)" "isoleucine-tRNA ligase activity (15%) ATP binding (15%) tRNA binding (13.8%)" "IPR002300 (13.1%) IPR023586 (13.1%) IPR014729 (13%)" "Aminoacyl-tRNA synthetase, class Ia (13.1%) Isoleucine-tRNA ligase, type 2 (13.1%) Rossmann-like alpha/beta/alpha sandwich fold (13%)" YNQVLDAWTHVNTDLGNLLMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (17%) GO:0000428 (17%) "GO:0003677 (17%) GO:0003899 (17%) GO:0000287 (16%)" DNA-templated transcription (17%) DNA-directed RNA polymerase complex (17%) "DNA binding (17%) DNA-directed RNA polymerase activity (17%) magnesium ion binding (16%)" "IPR007081 (9.6%) IPR007083 (9.6%) IPR000722 (9%)" "RNA polymerase Rpb1, domain 5 (9.6%) RNA polymerase Rpb1, domain 4 (9.6%) RNA polymerase, alpha subunit (9%)" NAGYQVDGDLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.1%) IPR002772 (11.1%) IPR013783 (11.1%)" "Glycoside hydrolase, family 3, N-terminal (11.1%) Glycoside hydrolase family 3 C-terminal domain (11.1%) Immunoglobulin-like fold (11.1%)" AASYAQAALDNSGCQPMSQSEWYNKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FMDSLDMLNLVTHVADAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (20.2%) IPR006235 (20.2%) IPR015422 (20.2%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (20.2%) O-acetylhomoserine/O-acetylserine sulfhydrylase (20.2%) Pyridoxal phosphate-dependent transferase, small domain (20.2%)" MDGNEDFSAANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR019847 (100%) Gliding motility associated protein GldN (100%) RATSVYLVDR root "3.1.13.1 (98.8%) 3.1.-.- (1.2%) 3.1.13.- (0%)" "exoribonuclease II (98.8%) Acting on ester bonds (1.2%) Exoribonucleases producing 5'-phosphomonoesters (0%)" "GO:0006402 (24.8%) GO:0006364 (0%) GO:0016075 (0%)" "GO:0005829 (24.7%) GO:0000932 (0.1%) GO:0000176 (0%)" "GO:0003723 (24.9%) GO:0008859 (24.4%) GO:0004540 (0.3%)" "mRNA catabolic process (24.8%) rRNA processing (0%) rRNA catabolic process (0%)" "cytosol (24.7%) P-body (0.1%) nuclear exosome (RNase complex) (0%)" "RNA binding (24.9%) exoribonuclease II activity (24.4%) RNA nuclease activity (0.3%)" "IPR001900 (10.7%) IPR050180 (10.7%) IPR012340 (10.7%)" "Ribonuclease II/R (10.7%) RNR Ribonuclease (10.7%) Nucleic acid-binding, OB-fold (10.7%)" VGDEVQLLGLGEDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.9%) GO:0032045 (13.5%)" "GO:0003746 (14.9%) GO:0005525 (14.9%) GO:0003924 (14.2%)" "cytosol (14.9%) guanyl-nucleotide exchange factor complex (13.5%)" "translation elongation factor activity (14.9%) GTP binding (14.9%) GTPase activity (14.2%)" "IPR004160 (8.6%) IPR004161 (8.6%) IPR009000 (8.6%)" "Translation elongation factor EFTu/EF1A, C-terminal (8.6%) Translation elongation factor EFTu-like, domain 2 (8.6%) Translation protein, beta-barrel domain superfamily (8.6%)" KYEVMNASEYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.4%) IPR012910 (13.4%) IPR023996 (13.4%)" "TonB-dependent receptor-like, beta-barrel (13.4%) TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%)" KLEVAYCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.9 (100%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acisynthase (100%) GO:0009234 (20.4%) "GO:0030976 (21%) GO:0070204 (20.4%) GO:0000287 (19.1%)" menaquinone biosynthetic process (20.4%) "thiamine pyrophosphate binding (21%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity (20.4%) magnesium ion binding (19.1%)" "IPR012001 (26%) IPR004433 (25.2%) IPR029061 (25.2%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (26%) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase (25.2%) Thiamin diphosphate-binding fold (25.2%)" PSPLYYAK root "4.2.1.20 (96%) 2.7.11.1 (4%)" "tryptophan synthase (96%) non-specific serine/threonine protein kinase (4%)" "GO:0000045 (2%) GO:0000422 (2%) GO:0010506 (2%)" "GO:0005737 (38%) GO:0005776 (2%) GO:0005829 (2%)" "GO:0004834 (38%) GO:0004674 (2%) GO:0005524 (2%)" "autophagosome assembly (2%) autophagy of mitochondrion (2%) regulation of autophagy (2%)" "cytoplasm (38%) autophagosome (2%) cytosol (2%)" "tryptophan synthase activity (38%) protein serine/threonine kinase activity (2%) ATP binding (2%)" "IPR023026 (19%) IPR036052 (19%) IPR006653 (18.5%)" "Tryptophan synthase beta chain/beta chain-like (19%) Tryptophan synthase beta chain-like, PALP domain superfamily (19%) Tryptophan synthase, beta chain, conserved site (18.5%)" THAWGQHSGDLVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.7%) GO:0009341 (25.7%) "GO:0004565 (25.7%) GO:0030246 (23%)" lactose catabolic process (25.7%) beta-galactosidase complex (25.7%) "beta-galactosidase activity (25.7%) carbohydrate binding (23%)" "IPR004199 (8.2%) IPR006102 (8.2%) IPR006103 (8.2%)" "Beta galactosidase small chain/ domain 5 (8.2%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8.2%) Glycoside hydrolase family 2, catalytic domain (8.2%)" SSAATLPVTMQTAEDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (33.3%) "GO:0015184 (33.3%) GO:0015293 (33.3%)" plasma membrane (33.3%) "L-cystine transmembrane transporter activity (33.3%) symporter activity (33.3%)" "IPR001991 (51.3%) IPR036458 (48.7%)" "Sodium:dicarboxylate symporter (51.3%) Sodium:dicarboxylate symporter superfamily (48.7%)" LYFQVQNAFTFTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (29.3%) GO:0009279 (41.5%) GO:0015344 (29.3%) siderophore transmembrane transport (29.3%) cell outer membrane (41.5%) siderophore uptake transmembrane transporter activity (29.3%) "IPR012910 (13.5%) IPR023996 (13.5%) IPR023997 (13.5%)" "TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.5%)" AGWGLTGVLPGSSYLSLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NSVQLLGNNTNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.2.7.1 (83.3%) 1.2.1.51 (16.7%)" "pyruvate synthase (83.3%) pyruvate dehydrogenase (NADP(+)) (16.7%)" "GO:0006979 (14.5%) GO:0022900 (14.5%) GO:0044281 (13%)" "GO:0005506 (14.5%) GO:0030976 (14.5%) GO:0051539 (14.5%)" "response to oxidative stress (14.5%) electron transport chain (14.5%) small molecule metabolic process (13%)" "iron ion binding (14.5%) thiamine pyrophosphate binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" VSYNFGSGLDEYLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" YLLQLLNSSATVDDLDHLSNRR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.1%) IPR007644 (8.1%) IPR015712 (8.1%)" "RNA polymerase Rpb2, domain 2 (8.1%) RNA polymerase, beta subunit, protrusion (8.1%) DNA-directed RNA polymerase, subunit 2 (8.1%)" LSAQLDFLYESLYDNDKAAFNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.7%) IPR003385 (20.7%) IPR013783 (19.6%)" "Carbohydrate binding module family 20 (20.7%) Glycoside hydrolase, family 77 (20.7%) Immunoglobulin-like fold (19.6%)" LENNEKLNVTFEEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" QLQFPNTSYGEDYALGLAFSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.8%) IPR013486 (12.8%) IPR013693 (12.8%)" "Glycosyltransferase 2-like (12.8%) Sporulation stage II protein D, amidase enhancer LytB (12.8%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.8%)" SEYDDLDPYSNRDPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.7%) IPR011990 (33.3%) IPR033985 (30%)" "RagB/SusD domain (36.7%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (30%)" DDMLAELHVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.7%) IPR008969 (48.3%)" "Family of unknown function DUF5686 (51.7%) Carboxypeptidase-like, regulatory domain superfamily (48.3%)" SLDTNPELDLSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19%) "GO:0000155 (20.2%) GO:0003700 (20.2%) GO:0005524 (20.2%)" membrane (19%) "phosphorelay sensor kinase activity (20.2%) DNA-binding transcription factor activity (20.2%) ATP binding (20.2%)" "IPR001789 (6.6%) IPR003594 (6.6%) IPR003661 (6.6%)" "Signal transduction response regulator, receiver domain (6.6%) Histidine kinase/HSP90-like ATPase domain (6.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.6%)" LLLTFYSPSGYEVR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.99.12 (100%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (100%) "GO:0009245 (25.3%) GO:0009244 (24.2%)" GO:0005886 (25.3%) "GO:0016740 (15.9%) GO:0043842 (9.3%)" "lipid A biosynthetic process (25.3%) lipopolysaccharide core region biosynthetic process (24.2%)" plasma membrane (25.3%) "transferase activity (15.9%) Kdo transferase activity (9.3%)" "IPR007507 (33.8%) IPR039901 (33.8%) IPR038107 (32.4%)" "3-deoxy-D-manno-octulosonic-acid transferase, N-terminal (33.8%) 3-deoxy-D-manno-octulosonic acid transferase (33.8%) 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily (32.4%)" LGFDDEFLYEELDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006152 (33.3%) "GO:0047974 (33.3%) GO:0046872 (31.5%) GO:0008270 (1.9%)" purine nucleoside catabolic process (33.3%) "guanosine deaminase activity (33.3%) metal ion binding (31.5%) zinc ion binding (1.9%)" "IPR002125 (50%) IPR016193 (47.2%) IPR016192 (2.8%)" "Cytidine and deoxycytidylate deaminase domain (50%) Cytidine deaminase-like (47.2%) APOBEC/CMP deaminase, zinc-binding (2.8%)" SLNYMGFQPGEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (24.8%) "GO:0046872 (24.8%) GO:0051539 (24.8%) GO:0003861 (23.9%)" L-leucine biosynthetic process (24.8%) "metal ion binding (24.8%) 4 iron, 4 sulfur cluster binding (24.8%) 3-isopropylmalate dehydratase activity (23.9%)" "IPR001030 (14.7%) IPR050067 (14.7%) IPR004430 (14.1%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.7%) Isopropylmalate dehydratase and related enzymes (14.7%) 3-isopropylmalate dehydratase, large subunit (14.1%)" KMEASVWTDPSVADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (23.3%) GO:0016020 (1.7%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (23.3%) membrane (1.7%)" protein-disulfide reductase activity (25%) "IPR003834 (25.2%) IPR013766 (25.2%) IPR028250 (25.2%)" "Cytochrome C biogenesis protein, transmembrane domain (25.2%) Thioredoxin domain (25.2%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.2%)" LGNENFVAHAPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20%) GO:0005829 (20%) "GO:0002161 (20%) GO:0004832 (20%) GO:0005524 (20%)" valyl-tRNA aminoacylation (20%) cytosol (20%) "aminoacyl-tRNA deacylase activity (20%) valine-tRNA ligase activity (20%) ATP binding (20%)" "IPR001412 (9.1%) IPR002300 (9.1%) IPR002303 (9.1%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.1%) Aminoacyl-tRNA synthetase, class Ia (9.1%) Valine-tRNA ligase (9.1%)" GANNYAALAEGYLNLPEDGVYYLSSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (18.1%) IPR015883 (17.4%) IPR025705 (17.4%)" "PA14 domain (18.1%) Glycoside hydrolase family 20, catalytic domain (17.4%) Beta-hexosaminidase (17.4%)" VWVCLDFQHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0043043 (33.3%) GO:0005829 (33.3%) GO:0003746 (33.3%) peptide biosynthetic process (33.3%) cytosol (33.3%) translation elongation factor activity (33.3%) "IPR001059 (11.1%) IPR008991 (11.1%) IPR011768 (11.1%)" "Translation elongation factor P/YeiP, central (11.1%) Translation protein SH3-like domain superfamily (11.1%) Translation elongation factor P (11.1%)" WSNVTYMPCDESDDFLPQLPDHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (33.3%) "GO:0010285 (33.3%) GO:0030170 (33.3%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (33.3%) "L,L-diaminopimelate aminotransferase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (21.6%) IPR019942 (21.6%) IPR015421 (18.9%)" "Aminotransferase, class I/classII, large domain (21.6%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21.6%) Pyridoxal phosphate-dependent transferase, major domain (18.9%)" LVPNLFLAPNTLSTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" SLSLNLTK root "5.3.1.9 (60%) 1.8.4.12 (6.7%) 2.1.1.72 (4.4%)" "glucose-6-phosphate isomerase (60%) peptide-methionine (R)-S-oxide reductase (6.7%) site-specific DNA-methyltransferase (adenine-specific) (4.4%)" "GO:0006094 (7.1%) GO:0006096 (7.1%) GO:0051156 (7.1%)" "GO:0005829 (7.9%) GO:0005886 (2.7%) GO:0016020 (1.9%)" "GO:0004347 (7.1%) GO:0048029 (7.1%) GO:0097367 (6.8%)" "gluconeogenesis (7.1%) glycolytic process (7.1%) glucose 6-phosphate metabolic process (7.1%)" "cytosol (7.9%) plasma membrane (2.7%) membrane (1.9%)" "glucose-6-phosphate isomerase activity (7.1%) monosaccharide binding (7.1%) carbohydrate derivative binding (6.8%)" "IPR001672 (6.6%) IPR018189 (6.6%) IPR035476 (6.6%)" "Phosphoglucose isomerase (PGI) (6.6%) Phosphoglucose isomerase, conserved site (6.6%) Phosphoglucose isomerase, SIS domain 1 (6.6%)" DEEGYFWFEGR root "6.2.1.1 (93.3%) 6.2.1.- (3.3%) 6.2.1.25 (3.3%)" "acetate--CoA ligase (93.3%) Acid--thiol ligases (3.3%) benzoate--CoA ligase (3.3%)" "GO:0006633 (15.9%) GO:0006637 (15.9%) GO:0006085 (0.5%)" "GO:0016020 (1.5%) GO:0005829 (0.5%)" "GO:0005524 (16.5%) GO:0004321 (15.9%) GO:0015645 (15.9%)" "fatty acid biosynthetic process (15.9%) acyl-CoA metabolic process (15.9%) acetyl-CoA biosynthetic process (0.5%)" "membrane (1.5%) cytosol (0.5%)" "ATP binding (16.5%) fatty-acyl-CoA synthase activity (15.9%) fatty acid ligase activity (15.9%)" "IPR000873 (16.8%) IPR025110 (16.8%) IPR042099 (16.7%)" "AMP-dependent synthetase/ligase domain (16.8%) AMP-binding enzyme, C-terminal domain (16.8%) ANL, N-terminal domain (16.7%)" GLSVGANFSYLWGSLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KAPSTFWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (51.8%) GO:0022857 (48.2%) membrane (51.8%) transmembrane transporter activity (48.2%) "IPR011701 (50%) IPR036259 (50%)" "Major facilitator superfamily (50%) MFS transporter superfamily (50%)" FLESASYLNFQSFSVGYTFPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LNETNLFR Bacteria Bacteria GO:0005975 (12.5%) "GO:0009279 (62.5%) GO:0005576 (12.5%)" GO:0016810 (12.5%) carbohydrate metabolic process (12.5%) "cell outer membrane (62.5%) extracellular region (12.5%)" hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (12.5%) "IPR000531 (11.4%) IPR012910 (11.4%) IPR023996 (11.4%)" "TonB-dependent receptor-like, beta-barrel (11.4%) TonB-dependent receptor, plug domain (11.4%) TonB-dependent outer membrane protein, SusC/RagA (11.4%)" NAEAPFYVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (20%) "GO:0005524 (20%) GO:0008784 (20%) GO:0016881 (20%)" D-alanine biosynthetic process (20%) "ATP binding (20%) alanine racemase activity (20%) acid-amino acid ligase activity (20%)" "IPR000821 (10%) IPR001608 (10%) IPR009006 (10%)" "Alanine racemase (10%) Alanine racemase, N-terminal (10%) Alanine racemase/group IV decarboxylase, C-terminal (10%)" TAAQQNHFLSAAGATEKVNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" TAYSEEPSFAESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.21 (100%) starch synthase (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR013534 (100%) Starch synthase, catalytic domain (100%) LNYYDHANLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.9%) IPR008969 (48.1%)" "Family of unknown function DUF5686 (51.9%) Carboxypeptidase-like, regulatory domain superfamily (48.1%)" CLGLNVLGVDASEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0006177 (0.3%) GO:0005829 (33.1%) "GO:0003921 (33.1%) GO:0005524 (33.1%) GO:0016740 (0.3%)" GMP biosynthetic process (0.3%) cytosol (33.1%) "GMP synthase activity (33.1%) ATP binding (33.1%) transferase activity (0.3%)" "IPR001674 (12.6%) IPR025777 (12.6%) IPR014729 (12.5%)" "GMP synthase, C-terminal (12.6%) GMP synthetase ATP pyrophosphatase domain (12.6%) Rossmann-like alpha/beta/alpha sandwich fold (12.5%)" LLENGGKPDFTR Bacteria Bacteria GO:0006004 (33.3%) GO:0005737 (33.3%) GO:0008736 (33.3%) fucose metabolic process (33.3%) cytoplasm (33.3%) L-fucose isomerase activity (33.3%) "IPR015888 (51.9%) IPR009015 (48.1%)" "L-fucose isomerase, C-terminal (51.9%) L-fucose isomerase, N-terminal/central domain superfamily (48.1%)" KQFLVMDMLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027417 (40%) IPR041685 (30%) IPR051396 (30%)" "P-loop containing nucleoside triphosphate hydrolase (40%) Endonuclease GajA/Old nuclease/RecF-like, AAA domain (30%) Bacterial Antiviral Defense Nuclease (30%)" NVDGEVLVSTNNDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (18.2%) IPR002890 (18.2%) IPR008930 (18.2%)" "Alpha-2-macroglobulin (18.2%) Macroglobulin domain (18.2%) Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid (18.2%)" SLFASTLQAYFEGRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (41.8%) IPR012547 (35.7%) IPR027417 (22.5%)" "AAA-ATPase-like domain (41.8%) PD-(D/E)XK nuclease superfamily 9 (35.7%) P-loop containing nucleoside triphosphate hydrolase (22.5%)" GTPEFDAAK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.3%) GO:0006096 (16.3%) GO:0044718 (0.7%)" "GO:0005829 (16.3%) GO:0009279 (0.7%)" "GO:0004618 (16.3%) GO:0005524 (16.3%) GO:0043531 (16.3%)" "gluconeogenesis (16.3%) glycolytic process (16.3%) siderophore transmembrane transport (0.7%)" "cytosol (16.3%) cell outer membrane (0.7%)" "phosphoglycerate kinase activity (16.3%) ATP binding (16.3%) ADP binding (16.3%)" "IPR001576 (31.9%) IPR015824 (31.9%) IPR036043 (31.9%)" "Phosphoglycerate kinase (31.9%) Phosphoglycerate kinase, N-terminal (31.9%) Phosphoglycerate kinase superfamily (31.9%)" DFNPNVQSVNWSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (37.5%) IPR011042 (31.3%) IPR029058 (31.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (37.5%) Six-bladed beta-propeller, TolB-like (31.3%) Alpha/Beta hydrolase fold (31.3%)" RQLMCPLPNNEPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0036376 (33.3%) GO:0005886 (33.3%) GO:0015081 (33.3%) sodium ion export across plasma membrane (33.3%) plasma membrane (33.3%) sodium ion transmembrane transporter activity (33.3%) "IPR005899 (64.6%) IPR001322 (35.4%)" "Sodium ion-translocating decarboxylase (64.6%) Lamin tail domain (35.4%)" SNNYNLALEHTGR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.7%) IPR008969 (16.7%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (16.7%) Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%)" QTYTAEQQKDDFWNYLNQDSYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.8%) GO:0009279 (36.4%) GO:0015344 (31.8%) siderophore transmembrane transport (31.8%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (31.8%) "IPR057601 (23.5%) IPR036942 (20.6%) IPR039426 (20.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (23.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.6%) TonB-dependent receptor-like (20.6%)" KLPNLFDASSVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (75%) GO:0005737 (8.3%) GO:0005886 (8.3%)" "extracellular space (75%) cytoplasm (8.3%) plasma membrane (8.3%)" "IPR001611 (16.8%) IPR027899 (15.6%) IPR032675 (15.6%)" "Leucine-rich repeat (16.8%) Domain of unknown function DUF4458 (15.6%) Leucine-rich repeat domain superfamily (15.6%)" MMAPVVESLAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045454 (25.9%) "GO:0005829 (25.9%) GO:0016020 (3.7%)" GO:0015035 (44.4%) cell redox homeostasis (25.9%) "cytosol (25.9%) membrane (3.7%)" protein-disulfide reductase activity (44.4%) "IPR005746 (25.5%) IPR013766 (25.5%) IPR017937 (25.5%)" "Thioredoxin (25.5%) Thioredoxin domain (25.5%) Thioredoxin, conserved site (25.5%)" TMEPDYELPEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.6%) "GO:0003677 (25.6%) GO:0003917 (25.6%) GO:0046872 (23.3%)" DNA topological change (25.6%) "DNA binding (25.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.6%) metal ion binding (23.3%)" "IPR000380 (7.5%) IPR003601 (7.5%) IPR006171 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, domain 2 (7.5%) TOPRIM domain (7.5%)" YLSEGFGGLEDGVASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025684 (50%) IPR026377 (50%)" "Gliding motility protein SprA N-terminal domain (50%) Cell surface SprA (50%)" GMELLASENFVSDEVMNAMGSYLTNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (17.4%) GO:0035999 (17.4%) GO:0032259 (6.4%)" GO:0005829 (17.4%) "GO:0004372 (17.4%) GO:0030170 (17.4%) GO:0008168 (6.4%)" "glycine biosynthetic process from serine (17.4%) tetrahydrofolate interconversion (17.4%) methylation (6.4%)" cytosol (17.4%) "glycine hydroxymethyltransferase activity (17.4%) pyridoxal phosphate binding (17.4%) methyltransferase activity (6.4%)" "IPR001085 (14.6%) IPR019798 (14.6%) IPR039429 (14.6%)" "Serine hydroxymethyltransferase (14.6%) Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.6%) Serine hydroxymethyltransferase-like domain (14.6%)" AYDEHVLR root GO:0045493 (25%) GO:0005886 (25%) "GO:0016757 (25%) GO:0031176 (25%)" xylan catabolic process (25%) plasma membrane (25%) "glycosyltransferase activity (25%) endo-1,4-beta-xylanase activity (25%)" "IPR000600 (30.2%) IPR049874 (30.2%) IPR043129 (28.3%)" "ROK family (30.2%) ROK, conserved site (30.2%) ATPase, nucleotide binding domain (28.3%)" FHLDWLR root "2.7.1.170 (78.3%) 1.4.1.2 (8.7%) 2.1.1.- (4.3%)" "anhydro-N-acetylmuramic acid kinase (78.3%) glutamate dehydrogenase (8.7%) Methyltransferases (4.3%)" "GO:0032259 (9.2%) GO:0006364 (8.4%) GO:0006040 (5.6%)" "GO:0005737 (9.2%) GO:0043235 (2%) GO:0005886 (1.2%)" "GO:0008168 (9.2%) GO:0003723 (8.8%) GO:0005524 (6%)" "methylation (9.2%) rRNA processing (8.4%) amino sugar metabolic process (5.6%)" "cytoplasm (9.2%) receptor complex (2%) plasma membrane (1.2%)" "methyltransferase activity (9.2%) RNA binding (8.8%) ATP binding (6%)" "IPR019614 (7.4%) IPR002478 (7.1%) IPR029063 (7.1%)" "S-adenosylmethionine-dependent methyltransferase (7.4%) PUA domain (7.1%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (7.1%)" SNVTDKQTFATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TPADLYSDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.13.- (100%) Dipeptidases (100%) GO:0006508 (50%) GO:0070573 (50%) proteolysis (50%) metallodipeptidase activity (50%) "IPR008257 (25.3%) IPR011697 (25.3%) IPR029062 (24.7%)" "Peptidase M19 (25.3%) Peptidase C26 (25.3%) Class I glutamine amidotransferase-like (24.7%)" EAVALLQR root "5.6.2.3 (19.7%) 2.7.7.19 (9.8%) 2.3.2.27 (8.2%)" "DNA 5'-3' helicase (19.7%) polynucleotide adenylyltransferase (9.8%) RING-type E3 ubiquitin transferase (8.2%)" "GO:0006355 (5.7%) GO:0006808 (4.7%) GO:0006269 (1.2%)" "GO:0005737 (7.7%) GO:0016020 (5%) GO:0005634 (3%)" "GO:0005524 (9.5%) GO:0043565 (4.9%) GO:0000156 (4.7%)" "regulation of DNA-templated transcription (5.7%) regulation of nitrogen utilization (4.7%) DNA replication, synthesis of primer (1.2%)" "cytoplasm (7.7%) membrane (5%) nucleus (3%)" "ATP binding (9.5%) sequence-specific DNA binding (4.9%) phosphorelay response regulator activity (4.7%)" "IPR027417 (5.3%) IPR003593 (4.2%) IPR009057 (3.5%)" "P-loop containing nucleoside triphosphate hydrolase (5.3%) AAA+ ATPase domain (4.2%) Homedomain-like superfamily (3.5%)" DTDELTLLTSVR Pseudomonadati Bacteria Pseudomonadati "GO:0008643 (32.9%) GO:0006814 (1.3%)" GO:0005886 (32.9%) GO:0015293 (32.9%) "carbohydrate transport (32.9%) sodium ion transport (1.3%)" plasma membrane (32.9%) symporter activity (32.9%) "IPR039672 (51%) IPR036259 (47.1%) IPR001927 (2%)" "Lactose permease-like (51%) MFS transporter superfamily (47.1%) Sodium:galactoside symporter (2%)" NDLAVAAPPPPPAPKPEVATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (16.7%) GO:0015891 (16.7%) GO:0055085 (16.7%)" "GO:0030288 (16.7%) GO:0098797 (16.7%)" GO:0031992 (16.7%) "protein transport (16.7%) siderophore transport (16.7%) transmembrane transport (16.7%)" "outer membrane-bounded periplasmic space (16.7%) plasma membrane protein complex (16.7%)" energy transducer activity (16.7%) "IPR003538 (25%) IPR006260 (25%) IPR037682 (25%)" "Gram-negative bacterial TonB protein (25%) TonB/TolA, C-terminal (25%) TonB, C-terminal (25%)" YYNQKPGTGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella ADYLLMSK root 2.3.1.257 (100%) N-terminal L-serine N(alpha)-acetyltransferase NatD (100%) GO:0016567 (1.4%) "GO:0016020 (39.4%) GO:0005634 (11.3%) GO:0005737 (11.3%)" "GO:0010485 (11.3%) GO:0043998 (11.3%) GO:1990189 (11.3%)" protein ubiquitination (1.4%) "membrane (39.4%) nucleus (11.3%) cytoplasm (11.3%)" "histone H4 acetyltransferase activity (11.3%) histone H2A acetyltransferase activity (11.3%) protein N-terminal-serine acetyltransferase activity (11.3%)" "IPR000182 (28.6%) IPR016181 (28.6%) IPR039949 (28.6%)" "GNAT domain (28.6%) Acyl-CoA N-acyltransferase (28.6%) N-alpha-acetyltransferase 40 (28.6%)" NLANLLNSSWGLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (20%) IPR036942 (20%) IPR037066 (20%)" "Carboxypeptidase-like, regulatory domain superfamily (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%) TonB-dependent receptor, plug domain superfamily (20%)" GLVNLKPLVSNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016491 (50%) GO:0008270 (47.4%) GO:0046872 (2.6%)" "oxidoreductase activity (50%) zinc ion binding (47.4%) metal ion binding (2.6%)" "IPR011032 (17%) IPR013149 (17%) IPR013154 (17%)" "GroES-like superfamily (17%) Alcohol dehydrogenase-like, C-terminal (17%) Alcohol dehydrogenase-like, N-terminal (17%)" GSDLLLHLADDCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0051082 (24.7%)" "ATP binding (24.7%) ATP hydrolysis activity (24.7%) unfolded protein binding (24.7%)" "IPR001404 (20%) IPR019805 (20%) IPR020575 (20%)" "Heat shock protein Hsp90 family (20%) Heat shock protein Hsp90, conserved site (20%) Heat shock protein Hsp90, N-terminal (20%)" WFEHSPVNNLSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QLLPSGDVDKDMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006654 (50%) GO:0003841 (50%) phosphatidic acid biosynthetic process (50%) 1-acylglycerol-3-phosphate O-acyltransferase activity (50%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) SAESDEALFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.7%) IPR013486 (12.7%) IPR013693 (12.7%)" "Glycosyltransferase 2-like (12.7%) Sporulation stage II protein D, amidase enhancer LytB (12.7%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.7%)" VAAYMDEQLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0019698 (32.8%) GO:0042840 (32.8%)" GO:0016746 (34.4%) "D-galacturonate catabolic process (32.8%) D-glucuronate catabolic process (32.8%)" acyltransferase activity (34.4%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) WLAQGTLYPDR root 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (33.2%) "GO:0003921 (33.2%) GO:0005524 (33.2%) GO:0016740 (0.2%)" cytosol (33.2%) "GMP synthase activity (33.2%) ATP binding (33.2%) transferase activity (0.2%)" "IPR001674 (12.6%) IPR025777 (12.6%) IPR004739 (12.5%)" "GMP synthase, C-terminal (12.6%) GMP synthetase ATP pyrophosphatase domain (12.6%) GMP synthase, glutamine amidotransferase (12.5%)" SVPLETGEK Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" NSGVMPYDVFNPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.1%) "GO:0004553 (34.1%) GO:0030246 (31.8%)" carbohydrate metabolic process (34.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.1%) carbohydrate binding (31.8%)" "IPR000322 (12.8%) IPR025887 (12.8%) IPR033403 (12.8%)" "Glycoside hydrolase family 31, TIM barrel domain (12.8%) Glycoside hydrolase family 31, N-terminal domain (12.8%) Domain of unknown function DUF5110 (12.8%)" FTVPTEEAVALFLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (33.3%) IPR018163 (33.3%) IPR027417 (33.3%)" "Phosphoribulokinase/uridine kinase (33.3%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" FGKTDATDEELANAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (22%) GO:0016020 (3%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (22%) membrane (3%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.8%) IPR003593 (14.8%) IPR011527 (14.8%)" "ABC transporter-like, ATP-binding domain (14.8%) AAA+ ATPase domain (14.8%) ABC transporter type 1, transmembrane domain (14.8%)" QVVTMAPEQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (34%) GO:0005737 (32.1%) GO:0008734 (34%) 'de novo' NAD+ biosynthetic process from L-aspartate (34%) cytoplasm (32.1%) L-aspartate oxidase activity (34%) "IPR003953 (17%) IPR005288 (17%) IPR027477 (17%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17%) L-aspartate oxidase (17%) Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily (17%)" TLTVSQNSTEGLLLTSSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (20%) IPR013783 (20%) IPR017853 (20%)" "Glycoside hydrolase, family 5 (20%) Immunoglobulin-like fold (20%) Glycoside hydrolase superfamily (20%)" ELLDKPVDFVLPNGFDNSFVPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) MMNALNNVSDGWSDTAFLLQGDLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" KHELNEELFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.3%) GO:0043335 (15.5%) GO:0051083 (15.5%)" GO:0005737 (5.4%) "GO:0003755 (15.5%) GO:0043022 (15.5%) GO:0044183 (15.5%)" "protein transport (16.3%) protein unfolding (15.5%) 'de novo' cotranslational protein folding (15.5%)" cytoplasm (5.4%) "peptidyl-prolyl cis-trans isomerase activity (15.5%) ribosome binding (15.5%) protein folding chaperone (15.5%)" "IPR005215 (19%) IPR008881 (19%) IPR037041 (19%)" "Trigger factor (19%) Trigger factor, ribosome-binding, bacterial (19%) Trigger factor, C-terminal domain superfamily (19%)" QPLYMGGALLAANK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (9.3%) "GO:0009279 (20.4%) GO:1990281 (20.4%)" "GO:0015288 (20.4%) GO:0015562 (20.4%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.4%) efflux pump complex (20.4%)" "porin activity (20.4%) efflux transmembrane transporter activity (20.4%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" DEVNHLLTFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) VLAQDNALNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (17%) GO:0006508 (16%)" GO:0005737 (17%) "GO:0005524 (17%) GO:0016887 (17%) GO:0008233 (16%)" "cellular response to heat (17%) proteolysis (16%)" cytoplasm (17%) "ATP binding (17%) ATP hydrolysis activity (17%) peptidase activity (16%)" "IPR001943 (9.5%) IPR041546 (9.5%) IPR050130 (9.5%)" "UVR domain (9.5%) ClpA/ClpB, AAA lid domain (9.5%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (9.5%)" ALVYAAER root "3.4.21.- (87.9%) 3.3.2.1 (6.1%) 2.7.8.- (3%)" "Serine endopeptidases (87.9%) isochorismatase (6.1%) Transferases for other substituted phosphate groups (3%)" "GO:0006508 (25.4%) GO:0006605 (1.6%) GO:0043952 (1.6%)" "GO:0005737 (26.2%) GO:0005886 (2.4%) GO:0005829 (0.8%)" "GO:0008236 (24.6%) GO:0008908 (2.4%) GO:0003723 (0.8%)" "proteolysis (25.4%) protein targeting (1.6%) protein transport by the Sec complex (1.6%)" "cytoplasm (26.2%) plasma membrane (2.4%) cytosol (0.8%)" "serine-type peptidase activity (24.6%) isochorismatase activity (2.4%) RNA binding (0.8%)" "IPR011659 (10.8%) IPR005151 (10.4%) IPR012393 (10.4%)" "WD40-like beta-propeller (10.8%) Tail specific protease (10.4%) Tricorn protease (10.4%)" QVLPLQLGDNLLGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR000253 (53.3%) IPR008984 (46.7%)" "Forkhead-associated (FHA) domain (53.3%) SMAD/FHA domain superfamily (46.7%)" GNLDETEVGSLVTGMPMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" NGLQEPVSLTLPSVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.2.29 (100%) peptidoglycan lytic transglycosylase (100%) "GO:0071555 (25.4%) GO:0009252 (23.9%)" GO:0005886 (25.4%) "GO:0008932 (23.9%) GO:0016829 (1.4%)" "cell wall organization (25.4%) peptidoglycan biosynthetic process (23.9%)" plasma membrane (25.4%) "lytic endotransglycosylase activity (23.9%) lyase activity (1.4%)" IPR003770 (100%) Endolytic murein transglycosylase (100%) TPYLNCYGAYVLNPDTQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.8%) GO:0005737 (32.3%) GO:0008734 (33.8%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.8%) cytoplasm (32.3%) L-aspartate oxidase activity (33.8%) "IPR003953 (17.3%) IPR005288 (17.3%) IPR015939 (16.5%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (17.3%) L-aspartate oxidase (17.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.5%)" EFWLEHTKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.8%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.8%)" TYHENLFELPFGENVTGELGYTVGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TLSADVLK root "2.7.1.150 (33.3%) 3.2.1.25 (16.7%) 3.6.4.13 (16.7%)" "1-phosphatidylinositol-3-phosphate 5-kinase (33.3%) beta-mannosidase (16.7%) RNA helicase (16.7%)" "GO:0005975 (5.5%) GO:0007165 (2.7%) GO:0009052 (1.4%)" "GO:0005886 (5.5%) GO:0009279 (4.1%) GO:0016020 (4.1%)" "GO:0004553 (3.4%) GO:0005524 (2.7%) GO:0015297 (2.7%)" "carbohydrate metabolic process (5.5%) signal transduction (2.7%) pentose-phosphate shunt, non-oxidative branch (1.4%)" "plasma membrane (5.5%) cell outer membrane (4.1%) membrane (4.1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (3.4%) ATP binding (2.7%) antiporter activity (2.7%)" "IPR025049 (4.5%) IPR042278 (3.7%) IPR012910 (2.6%)" "Fimbrillin-like 1 (4.5%) Fimbrillin-like 1, N-terminal (3.7%) TonB-dependent receptor, plug domain (2.6%)" YLEEEGVEK root "GO:0005975 (47.1%) GO:0007264 (1.4%)" "GO:0004553 (47.1%) GO:0001784 (1.4%) GO:0005085 (1.4%)" "carbohydrate metabolic process (47.1%) small GTPase-mediated signal transduction (1.4%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (47.1%) phosphotyrosine residue binding (1.4%) guanyl-nucleotide exchange factor activity (1.4%)" "IPR006710 (20%) IPR050727 (20%) IPR000772 (18.8%)" "Glycoside hydrolase, family 43 (20%) Glycosyl hydrolase 43 family arabinanases (20%) Ricin B, lectin domain (18.8%)" MLTVPSELSFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.8 (100%) hypoxanthine phosphoribosyltransferase (100%) "GO:0006166 (10%) GO:0006178 (10%) GO:0032263 (10%)" "GO:0005829 (10%) GO:0016020 (8.6%)" "GO:0000166 (10%) GO:0000287 (10%) GO:0004422 (10%)" "purine ribonucleoside salvage (10%) guanine salvage (10%) GMP salvage (10%)" "cytosol (10%) membrane (8.6%)" "nucleotide binding (10%) magnesium ion binding (10%) hypoxanthine phosphoribosyltransferase activity (10%)" "IPR000836 (25%) IPR005904 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (25%) Hypoxanthine phosphoribosyl transferase (25%) Phosphoribosyltransferase-like (25%)" DNKFYLPNNLQMGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTLKPGAQVMFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000723 (25.2%) GO:0006281 (25.2%)" GO:0016020 (24.5%) GO:0003678 (25.2%) "telomere maintenance (25.2%) DNA repair (25.2%)" membrane (24.5%) DNA helicase activity (25.2%) "IPR003593 (20.2%) IPR010285 (20.2%) IPR029491 (20.2%)" "AAA+ ATPase domain (20.2%) DNA helicase Pif1-like, DEAD-box helicase domain (20.2%) Helicase Helix-turn-helix domain (20.2%)" GYVDEPVDEALDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.72 (100%) quinolinate synthase (100%) GO:0034628 (20%) GO:0005829 (20%) "GO:0008987 (20%) GO:0046872 (20%) GO:0051539 (20%)" 'de novo' NAD+ biosynthetic process from L-aspartate (20%) cytosol (20%) "quinolinate synthetase A activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR003473 (52.8%) IPR036094 (47.2%)" "Quinolinate synthetase A (52.8%) Quinolinate synthetase A superfamily (47.2%)" LQSVGLQEQNAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (10.1%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (10.1%)" "IPR004463 (14.8%) IPR010084 (14.8%) IPR013114 (14.8%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.8%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.8%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%)" FSAMLDK root "6.3.5.5 (47.8%) 6.3.4.16 (40.9%) 1.1.1.103 (2.6%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (47.8%) carbamoyl-phosphate synthase (ammonia) (40.9%) L-threonine 3-dehydrogenase (2.6%)" "GO:0006541 (10%) GO:0006526 (9.8%) GO:0006221 (9.5%)" "GO:0005737 (10.7%) GO:0016020 (1.3%) GO:0005829 (1.2%)" "GO:0046872 (10.6%) GO:0005524 (10.3%) GO:0004088 (10%)" "glutamine metabolic process (10%) L-arginine biosynthetic process (9.8%) pyrimidine nucleotide biosynthetic process (9.5%)" "cytoplasm (10.7%) membrane (1.3%) cytosol (1.2%)" "metal ion binding (10.6%) ATP binding (10.3%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (10%)" "IPR005479 (7.3%) IPR005480 (7.3%) IPR011607 (7.3%)" "Carbamoyl phosphate synthase, ATP-binding domain (7.3%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (7.3%) Methylglyoxal synthase-like domain (7.3%)" YASDAVSAALFANLCDAAGVPCQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.4%) GO:0005737 (19.4%) "GO:0004177 (20.4%) GO:0008270 (20.4%) GO:0008237 (19.4%)" proteolysis (20.4%) cytoplasm (19.4%) "aminopeptidase activity (20.4%) zinc ion binding (20.4%) metallopeptidase activity (19.4%)" "IPR001948 (51.2%) IPR023358 (48.8%)" "Peptidase M18 (51.2%) Peptidase M18, domain 2 (48.8%)" CLDCPKPTCMEGCPVSLNLPSFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (49.3%) GO:0051536 (49.3%) GO:0004355 (1.5%)" "oxidoreductase activity (49.3%) iron-sulfur cluster binding (49.3%) glutamate synthase (NADPH) activity (1.5%)" "IPR017927 (11.3%) IPR019480 (11.3%) IPR023753 (11.3%)" "FAD-binding domain, ferredoxin reductase-type (11.3%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.3%) FAD/NAD(P)-binding domain (11.3%)" VVEYSQDYLFFYDQLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (34.1%) IPR004134 (34.1%) IPR038765 (31.8%)" "Cysteine peptidase, cysteine active site (34.1%) Peptidase C1B, bleomycin hydrolase (34.1%) Papain-like cysteine peptidase superfamily (31.8%)" LLEACGADYVFAPSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.1 (100%) pantoate--beta-alanine ligase (AMP-forming) (100%) GO:0015940 (25%) GO:0005829 (25%) "GO:0004592 (25%) GO:0005524 (25%)" pantothenate biosynthetic process (25%) cytosol (25%) "pantoate-beta-alanine ligase activity (25%) ATP binding (25%)" "IPR003721 (34%) IPR014729 (34%) IPR042176 (31.9%)" "Pantoate-beta-alanine ligase (34%) Rossmann-like alpha/beta/alpha sandwich fold (34%) Pantoate-beta-alanine ligase, C-terminal domain (31.9%)" NAAAVENGDWEVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" LPTGLNDK Bacteria Bacteria 3.2.2.0 (100%) Unknown (100%) "GO:0006457 (35.3%) GO:0042026 (5.9%) GO:0009691 (2.9%)" "GO:0005737 (5.9%) GO:0005829 (2.9%)" "GO:0051082 (41.2%) GO:0008270 (2.9%) GO:0008714 (2.9%)" "protein folding (35.3%) protein refolding (5.9%) cytokinin biosynthetic process (2.9%)" "cytoplasm (5.9%) cytosol (2.9%)" "unfolded protein binding (41.2%) zinc ion binding (2.9%) AMP nucleosidase activity (2.9%)" "IPR002939 (20.9%) IPR008971 (20.9%) IPR001623 (17.9%)" "Chaperone DnaJ, C-terminal (20.9%) HSP40/DnaJ peptide-binding (20.9%) DnaJ domain (17.9%)" TNNLLSAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LTVCDNSGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000218 (25%) IPR005745 (25%) IPR019972 (25%)" "Large ribosomal subunit protein uL14 (25%) Large ribosomal subunit protein uL14, bacteria (25%) Large ribosomal subunit protein uL14, conserved site (25%)" EDAFFGLR root "GO:0007165 (7.7%) GO:0000271 (3.8%) GO:0009246 (1.3%)" "GO:0016020 (41%) GO:0005886 (1.3%)" "GO:0016747 (35.9%) GO:0016791 (7.7%) GO:0016413 (1.3%)" "signal transduction (7.7%) polysaccharide biosynthetic process (3.8%) enterobacterial common antigen biosynthetic process (1.3%)" "membrane (41%) plasma membrane (1.3%)" "acyltransferase activity, transferring groups other than amino-acyl groups (35.9%) phosphatase activity (7.7%) O-acetyltransferase activity (1.3%)" "IPR002656 (51.8%) IPR001932 (10.7%) IPR003660 (10.7%)" "Acyltransferase 3 domain (51.8%) PPM-type phosphatase-like domain (10.7%) HAMP domain (10.7%)" APMANTAFLSPELSNDFVTNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) VQTALLVESGELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.4.1.13 (99.5%) 1.4.-.- (0.5%)" "glutamate synthase (NADPH) (99.5%) Acting on the CH-NH2 group of donors (0.5%)" "GO:0006537 (19.7%) GO:0019676 (19.6%)" "GO:0051538 (19.7%) GO:0046872 (19.4%) GO:0015930 (10.1%)" "glutamate biosynthetic process (19.7%) ammonia assimilation cycle (19.6%)" "3 iron, 4 sulfur cluster binding (19.7%) metal ion binding (19.4%) glutamate synthase activity (10.1%)" "IPR006982 (12.8%) IPR013785 (12.7%) IPR050711 (12.7%)" "Glutamate synthase, central-N (12.8%) Aldolase-type TIM barrel (12.7%) Electron transfer and nitrogen metabolism enzyme (12.7%)" VTSLGDLAMYTDADEVPLWEVLDSVSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR041218 (26.7%) IPR049280 (26.7%) IPR049281 (23.3%)" "Domain of unknown function DUF5606 (26.7%) Domain of unknown function DUF6852 (26.7%) BVU_3817-like, C-terminal domain superfamily (23.3%)" FALPFLR root "1.13.11.78 (18.8%) 2.3.2.27 (16.7%) 4.1.1.37 (15.2%)" "2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) (18.8%) RING-type E3 ubiquitin transferase (16.7%) uroporphyrinogen decarboxylase (15.2%)" "GO:0016567 (1.8%) GO:0071596 (1.8%) GO:1902600 (1.7%)" "GO:0016020 (11.9%) GO:0005886 (5.6%) GO:0005737 (3%)" "GO:0016787 (5.4%) GO:0046872 (3%) GO:0051539 (2.3%)" "protein ubiquitination (1.8%) ubiquitin-dependent protein catabolic process via the N-end rule pathway (1.8%) proton transmembrane transport (1.7%)" "membrane (11.9%) plasma membrane (5.6%) cytoplasm (3%)" "hydrolase activity (5.4%) metal ion binding (3%) 4 iron, 4 sulfur cluster binding (2.3%)" "IPR052567 (6.9%) IPR017670 (6.7%) IPR003607 (6.7%)" "Organophosphonate Dioxygenase (6.9%) Phosphonate degradation operon associated (6.7%) HD/PDEase domain (6.7%)" QPVWAVQFHPEVFHSLQGTQLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.9%) "GO:0003921 (32.9%) GO:0005524 (32.9%) GO:0016740 (1.3%)" cytosol (32.9%) "GMP synthase activity (32.9%) ATP binding (32.9%) transferase activity (1.3%)" "IPR004739 (12.9%) IPR017926 (12.9%) IPR001674 (12.4%)" "GMP synthase, glutamine amidotransferase (12.9%) Glutamine amidotransferase (12.9%) GMP synthase, C-terminal (12.4%)" SLSMVDAYWLGYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (49%) GO:0016787 (51%) membrane (49%) hydrolase activity (51%) "IPR005079 (33.8%) IPR052193 (33.8%) IPR029055 (32.5%)" "Peptidase C45, hydrolase domain (33.8%) Peptidase C59 family enzymes (33.8%) Nucleophile aminohydrolases, N-terminal (32.5%)" LLLTTEKDAVR Pseudomonadati Bacteria Pseudomonadati 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (51.5%) IPR027417 (48.5%)" "Tetraacyldisaccharide 4'-kinase (51.5%) P-loop containing nucleoside triphosphate hydrolase (48.5%)" MAAYGVNVDELNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (33.3%) IPR004763 (33.3%) IPR027463 (33.3%)" "Acriflavin resistance protein (33.3%) Cation efflux system CusA-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%)" LWELPVSSVHGLLGQFAPALAMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" QFADDWAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013118 (17.5%) IPR013131 (17.5%) IPR050988 (17.5%)" "Mannitol dehydrogenase, C-terminal (17.5%) Mannitol dehydrogenase, N-terminal (17.5%) Mannitol Dehydrogenase/Oxidoreductase (17.5%)" NPTLLFAGNNLGEDYLFELTSFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.8%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.8%)" "IPR001672 (20.2%) IPR018189 (20.2%) IPR035476 (20.2%)" "Phosphoglucose isomerase (PGI) (20.2%) Phosphoglucose isomerase, conserved site (20.2%) Phosphoglucose isomerase, SIS domain 1 (20.2%)" VGFPVLVR root "6.3.5.5 (64.1%) 6.3.4.16 (26.6%) 2.1.3.2 (4.4%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (64.1%) carbamoyl-phosphate synthase (ammonia) (26.6%) aspartate carbamoyltransferase (4.4%)" "GO:0006541 (12.4%) GO:0006526 (11.2%) GO:0006221 (8.2%)" "GO:0005737 (11.1%) GO:0005951 (1.8%) GO:0005739 (0.9%)" "GO:0046872 (13.6%) GO:0005524 (13.6%) GO:0004088 (13.6%)" "glutamine metabolic process (12.4%) L-arginine biosynthetic process (11.2%) pyrimidine nucleotide biosynthetic process (8.2%)" "cytoplasm (11.1%) carbamoyl-phosphate synthase complex (1.8%) mitochondrion (0.9%)" "metal ion binding (13.6%) ATP binding (13.6%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.6%)" "IPR005479 (9.2%) IPR011761 (9.2%) IPR005483 (9.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (9.2%) ATP-grasp fold (9.2%) Carbamoyl phosphate synthase, CPSase domain (9.1%)" YGSCPHAGFGLGFER Bacteria Bacteria 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004816 (20%) GO:0005524 (20%)" asparaginyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) asparagine-tRNA ligase activity (20%) ATP binding (20%)" "IPR004364 (14.4%) IPR004365 (14.4%) IPR004522 (14.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (14.4%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (14.4%) Asparagine-tRNA ligase (14.4%)" LSGMLDESFDTEQMKQPEQPYEFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (25.2%) GO:0016020 (25.2%) "GO:0004222 (25.2%) GO:0046872 (24.3%)" proteolysis (25.2%) membrane (25.2%) "metalloendopeptidase activity (25.2%) metal ion binding (24.3%)" "IPR004387 (25.5%) IPR008915 (25.5%) IPR041489 (24.5%)" "Peptidase M50, putative membrane-associated zinc metallopeptidase (25.5%) Peptidase M50 (25.5%) PDZ domain 6 (24.5%)" SFPFVSK root "6.3.4.16 (33.8%) 6.3.5.5 (32.3%) 2.1.3.2 (13.5%)" "carbamoyl-phosphate synthase (ammonia) (33.8%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (32.3%) aspartate carbamoyltransferase (13.5%)" "GO:0006526 (8.6%) GO:0006541 (8.6%) GO:0006207 (6.9%)" "GO:0005951 (5%) GO:0005739 (2.8%) GO:0005737 (2.6%)" "GO:0005524 (11.1%) GO:0004088 (11.1%) GO:0046872 (10.9%)" "L-arginine biosynthetic process (8.6%) glutamine metabolic process (8.6%) 'de novo' pyrimidine nucleobase biosynthetic process (6.9%)" "carbamoyl-phosphate synthase complex (5%) mitochondrion (2.8%) cytoplasm (2.6%)" "ATP binding (11.1%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (11.1%) metal ion binding (10.9%)" "IPR005479 (6.2%) IPR011761 (6.1%) IPR005483 (6.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (6.2%) ATP-grasp fold (6.1%) Carbamoyl phosphate synthase, CPSase domain (6.1%)" HFELLSQNLQPLLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.11.6 (100%) exodeoxyribonuclease VII (100%) GO:0006308 (20.3%) "GO:0009318 (20.3%) GO:0005737 (19.6%)" "GO:0008855 (20.3%) GO:0003676 (19.6%)" DNA catabolic process (20.3%) "exodeoxyribonuclease VII complex (20.3%) cytoplasm (19.6%)" "exodeoxyribonuclease VII activity (20.3%) nucleic acid binding (19.6%)" "IPR003753 (33.7%) IPR020579 (33.7%) IPR025824 (32.6%)" "Exonuclease VII, large subunit (33.7%) Exonuclease VII, large subunit, C-terminal (33.7%) OB-fold nucleic acid binding domain (32.6%)" LYVFDHNYNYDNLADQEDYPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006680 (33.3%) GO:0016020 (33.3%) GO:0004348 (33.3%) glucosylceramide catabolic process (33.3%) membrane (33.3%) glucosylceramidase activity (33.3%) "IPR001139 (20.9%) IPR033452 (20.9%) IPR033453 (20.9%)" "Glycoside hydrolase family 30 (20.9%) Glycosyl hydrolase family 30, beta sandwich domain (20.9%) Glycosyl hydrolase family 30, TIM-barrel domain (20.9%)" HNAQYAPLAVETFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR018873 (100%) KilA-N, DNA-binding domain (100%) YTAAAVGEVNVTTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.4.2.10 (96.6%) 5.4.2.8 (3.4%)" "phosphoglucosamine mutase (96.6%) phosphomannomutase (3.4%)" "GO:0005975 (14.3%) GO:0006048 (14.3%) GO:0009252 (14.3%)" GO:0005829 (14.3%) "GO:0000287 (14.3%) GO:0004615 (14.3%) GO:0008966 (14.3%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.3%) peptidoglycan biosynthetic process (14.3%)" cytosol (14.3%) "magnesium ion binding (14.3%) phosphomannomutase activity (14.3%) phosphoglucosamine mutase activity (14.3%)" "IPR005843 (10.1%) IPR005844 (10.1%) IPR005845 (10.1%)" "Alpha-D-phosphohexomutase, C-terminal (10.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (10.1%)" DFVEMPSQFNESFASLPELFDHYAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (50%) 3.4.24.- (50%)" "Acting on peptide bonds (peptidases) (50%) Metalloendopeptidases (50%)" GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR045090 (20.5%) IPR034005 (20%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidase M3A/M3B (20.5%) Peptidyl-dipeptidase DCP (20%)" FVFDCQAGSSNGLLQVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MSSALDLTYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (94.1%) GO:0004180 (5.9%) cell outer membrane (94.1%) carboxypeptidase activity (5.9%) "IPR012910 (30.2%) IPR008969 (29.6%) IPR037066 (29.6%)" "TonB-dependent receptor, plug domain (30.2%) Carboxypeptidase-like, regulatory domain superfamily (29.6%) TonB-dependent receptor, plug domain superfamily (29.6%)" LAEGAADSQLKPFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.6.5.9 (100%) NADH:ubiquinone reductase (non-electrogenic) (100%) GO:0003954 (100%) NADH dehydrogenase activity (100%) "IPR023753 (25%) IPR036188 (25%) IPR045024 (25%)" "FAD/NAD(P)-binding domain (25%) FAD/NAD(P)-binding domain superfamily (25%) Alternative NADH dehydrogenase (25%)" LVAEHLGTVHHELNYTLQEGLDALR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" TKFFTSFGYNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" YKGWDVAELLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045004 (25%) GO:0005829 (23.7%) "GO:0003676 (25%) GO:0008408 (25%) GO:0004527 (1.3%)" DNA replication proofreading (25%) cytosol (23.7%) "nucleic acid binding (25%) 3'-5' exonuclease activity (25%) exonuclease activity (1.3%)" "IPR046768 (26%) IPR012337 (24.7%) IPR013520 (24.7%)" "Exodeoxyribonuclease X-like, C-terminal (26%) Ribonuclease H-like superfamily (24.7%) Ribonuclease H-like domain (24.7%)" VTSDYALLQPQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (73.9%) IPR008160 (26.1%)" "Domain of unknown function DUF4988 (73.9%) Collagen triple helix repeat (26.1%)" ENLVMSLTEYLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.4.1.13 (98%) 1.4.-.- (2%)" "glutamate synthase (NADPH) (98%) Acting on the CH-NH2 group of donors (2%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.5%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.5%)" "IPR006982 (12.9%) IPR002489 (12.6%) IPR002932 (12.6%)" "Glutamate synthase, central-N (12.9%) Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase domain (12.6%)" NEGNLLPLQHGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.1%) GO:0005975 (1.9%)" "GO:0008422 (48.1%) GO:0004553 (1.9%)" "glucan catabolic process (48.1%) carbohydrate metabolic process (1.9%)" "beta-glucosidase activity (48.1%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.9%)" "IPR002772 (12.9%) IPR001764 (12.4%) IPR013783 (12.4%)" "Glycoside hydrolase family 3 C-terminal domain (12.9%) Glycoside hydrolase, family 3, N-terminal (12.4%) Immunoglobulin-like fold (12.4%)" NLGLNALHFQPVFDFASLDETR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50.7%) "GO:0016798 (34.3%) GO:0051060 (14.9%)" carbohydrate metabolic process (50.7%) "hydrolase activity, acting on glycosyl bonds (34.3%) pullulanase activity (14.9%)" "IPR006047 (15.1%) IPR011840 (14.7%) IPR049117 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (15.1%) Pullulanase, type I (14.7%) Pullulanase, all-beta domain (14.7%)" NTTLSSFK root "5.3.1.4 (90.5%) 1.3.3.8 (4.8%) 3.1.1.4 (4.8%)" "L-arabinose isomerase (90.5%) tetrahydroberberine oxidase (4.8%) phospholipase A2 (4.8%)" "GO:0019569 (20%) GO:0007165 (1.1%) GO:0008206 (1.1%)" "GO:0005829 (21.1%) GO:0016020 (2.2%) GO:0005576 (1.1%)" "GO:0008733 (20%) GO:0030145 (20%) GO:0005509 (2.2%)" "L-arabinose catabolic process to D-xylulose 5-phosphate (20%) signal transduction (1.1%) bile acid metabolic process (1.1%)" "cytosol (21.1%) membrane (2.2%) extracellular region (1.1%)" "L-arabinose isomerase activity (20%) manganese ion binding (20%) calcium ion binding (2.2%)" "IPR003762 (11.9%) IPR024664 (11.9%) IPR055389 (11.9%)" "L-arabinose isomerase (11.9%) L-arabinose isomerase, C-terminal (11.9%) L-arabinose isomerase, N-terminal domain (11.9%)" LEEANYAGNYPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri APFEQLEGYVLSPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" AGVSLSFTPWLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" EGGEPQKVNLSLTTDNDAPSLVR Pseudomonadati Bacteria Pseudomonadati 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR011659 (14.6%) IPR005151 (14.2%) IPR012393 (14.2%)" "WD40-like beta-propeller (14.6%) Tail specific protease (14.2%) Tricorn protease (14.2%)" NPSNPAVVSELDGEVTMGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (16.9%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.2%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.2%)" "IPR007081 (9.2%) IPR045867 (9.2%) IPR007083 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.2%) DNA-directed RNA polymerase, subunit beta-prime (9.2%) RNA polymerase Rpb1, domain 4 (9.1%)" QYVADNNPDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) "GO:0008422 (47.4%) GO:0004553 (2.6%)" carbohydrate metabolic process (50%) "beta-glucosidase activity (47.4%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.6%)" "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" RTDYNYSEVADALK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) EFPFEDTTVLLPEQADTYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009100 (100%) glycoprotein metabolic process (100%) "IPR007074 (50%) IPR052942 (46.7%) IPR043519 (3.3%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (50%) Lipopolysaccharide cholinephosphotransferase (46.7%) Nucleotidyltransferase superfamily (3.3%)" DDTLQGEVEVSEYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990961 (7.3%) "GO:0016020 (78%) GO:0019898 (7.3%) GO:1990195 (7.3%)" xenobiotic detoxification by transmembrane export across the plasma membrane (7.3%) "membrane (78%) extrinsic component of membrane (7.3%) macrolide transmembrane transporter complex (7.3%)" "IPR011053 (47.1%) IPR032317 (44.1%) IPR030190 (4.4%)" "Single hybrid motif (47.1%) Unknown (44.1%) Macrolide export protein MacA, alpha-hairpin domain superfamily (4.4%)" VECTDPLDR root "6.-.-.- (75%) 6.4.1.3 (25%)" "Ligases (75%) propionyl-CoA carboxylase (25%)" "GO:0015977 (21.8%) GO:0006633 (5.1%) GO:0006552 (0.4%)" GO:0009317 (21.8%) "GO:0004658 (23.6%) GO:0003989 (21.8%) GO:0016740 (4.7%)" "carbon fixation (21.8%) fatty acid biosynthetic process (5.1%) L-leucine catabolic process (0.4%)" acetyl-CoA carboxylase complex (21.8%) "propionyl-CoA carboxylase activity (23.6%) acetyl-CoA carboxylase activity (21.8%) transferase activity (4.7%)" "IPR011762 (19.3%) IPR011763 (19.3%) IPR034733 (19.3%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.3%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.3%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.3%)" LDGNLLELVPNMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) "GO:0006289 (12.2%) GO:0006281 (0.4%)" "GO:0005737 (12.7%) GO:0009380 (12.2%)" "GO:0003677 (12.7%) GO:0004518 (12.7%) GO:0005524 (12.7%)" "nucleotide-excision repair (12.2%) DNA repair (0.4%)" "cytoplasm (12.7%) excinuclease repair complex (12.2%)" "DNA binding (12.7%) nuclease activity (12.7%) ATP binding (12.7%)" "IPR041102 (14.9%) IPR003439 (14.4%) IPR004602 (14.4%)" "UvrA, interaction domain (14.9%) ABC transporter-like, ATP-binding domain (14.4%) UvrABC system subunit A (14.4%)" LAVVGSGPSGLSFAGDMAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0051536 (50%) GO:0016491 (45.5%) GO:0004355 (4.5%)" "iron-sulfur cluster binding (50%) oxidoreductase activity (45.5%) glutamate synthase (NADPH) activity (4.5%)" "IPR006004 (11.3%) IPR009051 (11.3%) IPR023753 (11.3%)" "Sulfide dehydrogenase subunit alpha-like (11.3%) Alpha-helical ferredoxin (11.3%) FAD/NAD(P)-binding domain (11.3%)" LDFLPLK root "2.1.1.72 (51.8%) 1.2.1.44 (3.5%) 2.7.13.3 (3.5%)" "site-specific DNA-methyltransferase (adenine-specific) (51.8%) cinnamoyl-CoA reductase (3.5%) histidine kinase (3.5%)" "GO:0043161 (16.2%) GO:0045047 (15.1%) GO:0009750 (1.5%)" "GO:0005783 (16.2%) GO:0016020 (2.5%) GO:0000502 (1.8%)" "GO:0008270 (17.5%) GO:0003700 (1.7%) GO:0000976 (1.6%)" "proteasome-mediated ubiquitin-dependent protein catabolic process (16.2%) protein targeting to ER (15.1%) response to fructose (1.5%)" "endoplasmic reticulum (16.2%) membrane (2.5%) proteasome complex (1.8%)" "zinc ion binding (17.5%) DNA-binding transcription factor activity (1.7%) transcription cis-regulatory region binding (1.6%)" "IPR000058 (18%) IPR035896 (18%) IPR057357 (16.4%)" "Zinc finger, AN1-type (18%) AN1-like Zinc finger (18%) ZFAND2A/B-like, C2H2 zinc finger (16.4%)" YYLSGNVK root "GO:0006974 (21.4%) GO:0001736 (3.6%) GO:0007156 (3.6%)" "GO:0044666 (21.4%) GO:0009279 (9.5%) GO:0005886 (3.6%)" "GO:0005509 (3.6%) GO:0003677 (2.4%) GO:0004386 (2.4%)" "DNA damage response (21.4%) establishment of planar polarity (3.6%) homophilic cell-cell adhesion (3.6%)" "MLL3/4 complex (21.4%) cell outer membrane (9.5%) plasma membrane (3.6%)" "calcium ion binding (3.6%) DNA binding (2.4%) helicase activity (2.4%)" "IPR001357 (11.9%) IPR036420 (11.9%) IPR051579 (11.9%)" "BRCT domain (11.9%) BRCT domain superfamily (11.9%) DNA Damage Response and Transcriptional Regulator (11.9%)" VGLELEAGEFKPNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (33.3%) GO:0005829 (33.3%) GO:0004056 (33.3%) L-arginine biosynthetic process via ornithine (33.3%) cytosol (33.3%) argininosuccinate lyase activity (33.3%) "IPR009049 (17.1%) IPR020557 (17.1%) IPR022761 (17.1%)" "Argininosuccinate lyase (17.1%) Fumarate lyase, conserved site (17.1%) Fumarate lyase, N-terminal (17.1%)" DLGETATENEYNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR038726 (34.7%) IPR011604 (32.7%) IPR027417 (32.7%)" "PD-(D/E)XK endonuclease-like domain, AddAB-type (34.7%) PD-(D/E)XK endonuclease-like domain superfamily (32.7%) P-loop containing nucleoside triphosphate hydrolase (32.7%)" VFDPDSGLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (31.6%) GO:0009982 (1.7%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (31.6%) pseudouridine synthase activity (1.7%)" "IPR006145 (14.7%) IPR006224 (14.7%) IPR050188 (14.7%)" "Pseudouridine synthase, RsuA/RluA-like (14.7%) Pseudouridine synthase, RluA-like, conserved site (14.7%) RluA Pseudouridine Synthase (14.7%)" HYDDVLDDLLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004386 (100%) helicase activity (100%) "IPR041677 (20.3%) IPR045055 (20.3%) IPR027417 (19.8%)" "DNA2/NAM7 helicase, helicase domain (20.3%) DNA2/NAM7-like helicase (20.3%) P-loop containing nucleoside triphosphate hydrolase (19.8%)" PGFMGNDYAFSTTAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (100%) outer membrane (100%) "IPR000184 (81.8%) IPR036709 (18.2%)" "Bacterial surface antigen (D15) (81.8%) Autotransporter beta-domain superfamily (18.2%)" YEMTFANNLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LNEVLKFDNFEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (51.5%) GO:0050660 (48.5%) plasma membrane (51.5%) flavin adenine dinucleotide binding (48.5%) "IPR000644 (14.9%) IPR005170 (14.9%) IPR002550 (14%)" "CBS domain (14.9%) Transporter-associated domain (14.9%) CNNM, transmembrane domain (14%)" VALYGLDFLLEEK Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.5%) GO:0005829 (33.3%) "GO:0008861 (33.3%) GO:0016829 (0.8%)" glucose metabolic process (32.5%) cytosol (33.3%) "formate C-acetyltransferase activity (33.3%) lyase activity (0.8%)" "IPR004184 (20.3%) IPR050244 (20.3%) IPR001150 (19.8%)" "Pyruvate formate lyase domain (20.3%) Autonomous Glycyl Radical Cofactor (20.3%) Glycine radical domain (19.8%)" HLCNSAGLEHFPER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (20%) "GO:0005524 (20%) GO:0008784 (20%) GO:0016881 (20%)" D-alanine biosynthetic process (20%) "ATP binding (20%) alanine racemase activity (20%) acid-amino acid ligase activity (20%)" "IPR000821 (10.2%) IPR001608 (10.2%) IPR011079 (10.2%)" "Alanine racemase (10.2%) Alanine racemase, N-terminal (10.2%) Alanine racemase, C-terminal (10.2%)" SYLMYNDLMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0005975 (19%) GO:0006516 (19%)" GO:0005829 (19%) "GO:0000224 (19%) GO:0030246 (19%) GO:0016798 (4.8%)" "carbohydrate metabolic process (19%) glycoprotein catabolic process (19%)" cytosol (19%) "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (19%) carbohydrate binding (19%) hydrolase activity, acting on glycosyl bonds (4.8%)" "IPR005887 (16.7%) IPR008928 (16.7%) IPR012939 (16.7%)" "Glycosyl hydrolase family 92, alpha-1,2-mannosidase, putative (16.7%) Six-hairpin glycosidase superfamily (16.7%) Glycosyl hydrolase family 92 (16.7%)" TNVPSKPDSTVAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) ADDVNWVLPHEANLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20.6%) GO:0044550 (20.6%)" GO:0005737 (19.1%) "GO:0004315 (20.6%) GO:0033818 (19.1%)" "fatty acid biosynthetic process (20.6%) secondary metabolite biosynthetic process (20.6%)" cytoplasm (19.1%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20.6%) beta-ketoacyl-acyl-carrier-protein synthase III activity (19.1%)" "IPR013747 (25.5%) IPR013751 (25.5%) IPR016039 (25.5%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25.5%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25.5%) Thiolase-like (25.5%)" AMFYLDLAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35%) IPR033985 (35%) IPR012944 (30%)" "Tetratricopeptide-like helical domain superfamily (35%) SusD-like, N-terminal (35%) RagB/SusD domain (30%)" LNSLEDAVK root "3.5.4.25 (43.6%) 4.1.99.12 (43.6%) 2.7.1.35 (10.3%)" "GTP cyclohydrolase II (43.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (43.6%) pyridoxal kinase (10.3%)" "GO:0009231 (11.3%) GO:0009443 (1.4%)" "GO:0005829 (12.7%) GO:0016020 (1.4%)" "GO:0000287 (12.7%) GO:0003935 (11.3%) GO:0005525 (11.3%)" "riboflavin biosynthetic process (11.3%) pyridoxal 5'-phosphate salvage (1.4%)" "cytosol (12.7%) membrane (1.4%)" "magnesium ion binding (12.7%) GTP cyclohydrolase II activity (11.3%) GTP binding (11.3%)" "IPR000422 (13.9%) IPR000926 (13.9%) IPR016299 (13.9%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (13.9%) GTP cyclohydrolase II, RibA (13.9%) Riboflavin biosynthesis protein RibBA (13.9%)" TGFTASWK root "GO:0006508 (36.7%) GO:0009566 (6.7%)" "GO:0005615 (10%) GO:0016020 (10%)" "GO:0008237 (20%) GO:0004252 (16.7%)" "proteolysis (36.7%) fertilization (6.7%)" "extracellular space (10%) membrane (10%)" "metallopeptidase activity (20%) serine-type endopeptidase activity (16.7%)" "IPR003961 (9%) IPR008757 (9%) IPR000859 (7.5%)" "Fibronectin type III (9%) Peptidase M6-like, domain (9%) CUB domain (7.5%)" ETPDATAEDKETFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0046872 (50%) GO:0051536 (50%)" "metal ion binding (50%) iron-sulfur cluster binding (50%)" "IPR029039 (25.9%) IPR047964 (25.9%) IPR017896 (24.1%)" "Flavoprotein-like superfamily (25.9%) Polyferredoxin EFR1-like (25.9%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (24.1%)" VDSLTGQAFLSLAQSVVTVVNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016226 (16.7%) "GO:0005524 (16.7%) GO:0016887 (16.7%) GO:0046872 (16.7%)" iron-sulfur cluster assembly (16.7%) "ATP binding (16.7%) ATP hydrolysis activity (16.7%) metal ion binding (16.7%)" "IPR019591 (20%) IPR027417 (20%) IPR033756 (20%)" "Mrp/NBP35 ATP-binding protein (20%) P-loop containing nucleoside triphosphate hydrolase (20%) Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 (20%)" AYLTYSSDTDNGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (28.3%) "GO:0003723 (28.3%) GO:0009982 (15%) GO:0140098 (15%)" enzyme-directed rRNA pseudouridine synthesis (28.3%) "RNA binding (28.3%) pseudouridine synthase activity (15%) catalytic activity, acting on RNA (15%)" "IPR006145 (22.4%) IPR006225 (22.4%) IPR020103 (22.4%)" "Pseudouridine synthase, RsuA/RluA-like (22.4%) Pseudouridine synthase, RluC/RluD (22.4%) Pseudouridine synthase, catalytic domain superfamily (22.4%)" LAFAGTNEVHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (33.8%) IPR050386 (33.8%) IPR017853 (32.3%)" "Glycoside hydrolase, family 5 (33.8%) Glycosyl Hydrolase 5 (Cellulase A) (33.8%) Glycoside hydrolase superfamily (32.3%)" FLDLALR root "7.6.2.1 (20.4%) 2.7.11.1 (19.6%) 1.2.1.84 (4.2%)" "P-type phospholipid transporter (20.4%) non-specific serine/threonine protein kinase (19.6%) alcohol-forming fatty acyl-CoA reductase (NADPH) (4.2%)" "GO:0005975 (3.9%) GO:0045893 (3.7%) GO:0007166 (1.4%)" "GO:0016020 (5.4%) GO:0005886 (4.4%) GO:0005829 (4.4%)" "GO:0005524 (5.8%) GO:0042802 (3.7%) GO:0000156 (3.7%)" "carbohydrate metabolic process (3.9%) positive regulation of DNA-templated transcription (3.7%) cell surface receptor signaling pathway (1.4%)" "membrane (5.4%) plasma membrane (4.4%) cytosol (4.4%)" "ATP binding (5.8%) identical protein binding (3.7%) phosphorelay response regulator activity (3.7%)" "IPR036388 (2.7%) IPR001789 (2.5%) IPR011006 (2.5%)" "Winged helix-like DNA-binding domain superfamily (2.7%) Signal transduction response regulator, receiver domain (2.5%) CheY-like superfamily (2.5%)" GANGVVLVK Pseudomonadati Bacteria Pseudomonadati GO:0044718 (1.2%) GO:0009279 (96.5%) "GO:0004866 (1.2%) GO:0015344 (1.2%)" siderophore transmembrane transport (1.2%) cell outer membrane (96.5%) "endopeptidase inhibitor activity (1.2%) siderophore uptake transmembrane transporter activity (1.2%)" "IPR012910 (15.7%) IPR023997 (15.7%) IPR039426 (15.6%)" "TonB-dependent receptor, plug domain (15.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.7%) TonB-dependent receptor-like (15.6%)" KFALTLGDELPSGLLQMAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (8.1%) IPR007121 (8.1%) IPR007645 (8.1%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.1%) RNA polymerase, beta subunit, conserved site (8.1%) RNA polymerase Rpb2, domain 3 (8.1%)" ANDGLTPLYSAEDLYNHGLGTNPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.6%) IPR023996 (34.6%) IPR037066 (30.8%)" "TonB-dependent receptor, plug domain (34.6%) TonB-dependent outer membrane protein, SusC/RagA (34.6%) TonB-dependent receptor, plug domain superfamily (30.8%)" ELDEMFMR root "3.5.4.26 (50%) 1.1.1.193 (48.8%) 3.5.4.33 (1.2%)" "diaminohydroxyphosphoribosylaminopyrimidine deaminase (50%) 5-amino-6-(5-phosphoribosylamino)uracil reductase (48.8%) tRNA(adenine(34)) deaminase (1.2%)" "GO:0009231 (23.5%) GO:0002100 (0.6%)" "GO:0016020 (1.8%) GO:0009507 (0.6%)" "GO:0046872 (24.1%) GO:0008703 (23.5%) GO:0008835 (23.5%)" "riboflavin biosynthetic process (23.5%) tRNA wobble adenosine to inosine editing (0.6%)" "membrane (1.8%) chloroplast (0.6%)" "metal ion binding (24.1%) 5-amino-6-(5-phosphoribosylamino)uracil reductase activity (23.5%) diaminohydroxyphosphoribosylaminopyrimidine deaminase activity (23.5%)" "IPR002125 (18.7%) IPR002734 (18.3%) IPR004794 (18.3%)" "Cytidine and deoxycytidylate deaminase domain (18.7%) Bacterial bifunctional deaminase-reductase, C-terminal (18.3%) Riboflavin biosynthesis protein RibD (18.3%)" NTLEYLGLWEK Bacteria Bacteria GO:0003677 (100%) DNA binding (100%) "IPR018004 (52.7%) IPR017880 (47.3%)" "KilA/APSES-type HTH, DNA-binding (52.7%) KilA, N-terminal (47.3%)" LYPEMNFLGVDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.1.33 (100%) tRNA (guanine(46)-N(7))-methyltransferase (100%) GO:0043527 (50%) GO:0008176 (50%) tRNA methyltransferase complex (50%) tRNA (guanine(46)-N7)-methyltransferase activity (50%) "IPR003358 (33.3%) IPR029063 (33.3%) IPR055361 (33.3%)" "tRNA (guanine-N-7) methyltransferase, Trmb type (33.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%) tRNA (guanine-N(7)-)-methyltransferase TrmB, bacteria (33.3%)" MLLDYQNVSLYQADK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006865 (1.6%) GO:0051301 (1.6%)" GO:0005886 (23.4%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (23.4%)" "amino acid transport (1.6%) cell division (1.6%)" plasma membrane (23.4%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (23.4%)" "IPR003439 (20.8%) IPR003593 (19.5%) IPR015854 (19.5%)" "ABC transporter-like, ATP-binding domain (20.8%) AAA+ ATPase domain (19.5%) ABC transporter, lipoprotein release, LolD-like (19.5%)" SFGSFTAK root "GO:0006607 (12.5%) GO:0006999 (12.5%) GO:0036228 (12.5%)" "GO:0031965 (12.5%) GO:0044613 (12.5%) GO:0016020 (4.2%)" "GO:0017056 (12.5%) GO:0031625 (4.2%)" "NLS-bearing protein import into nucleus (12.5%) nuclear pore organization (12.5%) protein localization to nuclear inner membrane (12.5%)" "nuclear membrane (12.5%) nuclear pore central transport channel (12.5%) membrane (4.2%)" "structural constituent of nuclear pore (12.5%) ubiquitin protein ligase binding (4.2%)" "IPR010239 (15%) IPR024864 (15%) IPR025712 (15%)" "Conserved hypothetical protein CHP02001 (15%) Nucleoporin Nup54/Nup57/Nup44 (15%) Nucleoporin Nup54, alpha-helical domain (15%)" YDGTNDAAFDGVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (17.2%) IPR026906 (17.2%) IPR025896 (16.4%)" "Peptidase C10, streptopain (17.2%) BspA-type LRR region (17.2%) Spi protease inhibitor (16.4%)" YTAELTANGNDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.6%) IPR010720 (14.6%) IPR051563 (14.6%)" "Carbohydrate-binding, CenC-like (14.6%) Alpha-L-arabinofuranosidase, C-terminal (14.6%) Glycosyl Hydrolase Family 51 (14.6%)" AGAVLEGSKDFAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20%) GO:0006189 (19.6%) GO:0006164 (0.2%)" "GO:0004637 (20%) GO:0005524 (20%) GO:0046872 (20%)" "purine nucleobase biosynthetic process (20%) 'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.2%)" "phosphoribosylamine-glycine ligase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000115 (11.3%) IPR011761 (11.3%) IPR020561 (11.3%)" "Phosphoribosylglycinamide synthetase (11.3%) ATP-grasp fold (11.3%) Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (11.3%)" VNEAEMQLTQAEDGLALSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.3%) "GO:0009279 (20.3%) GO:1990281 (20.3%)" "GO:0015288 (20.3%) GO:0015562 (20.3%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.3%) efflux pump complex (20.3%)" "porin activity (20.3%) efflux transmembrane transporter activity (20.3%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" GALPLALR root "2.4.1.21 (62.5%) 2.7.13.3 (7.5%) 7.2.2.6 (5%)" "starch synthase (62.5%) histidine kinase (7.5%) P-type K(+) transporter (5%)" "GO:0005978 (3.9%) GO:0006355 (3.9%) GO:0000160 (3.7%)" "GO:0016020 (4.1%) GO:0005886 (3.1%) GO:0005829 (1.9%)" "GO:0005524 (12.3%) GO:0003677 (4.9%) GO:0043531 (4.4%)" "glycogen biosynthetic process (3.9%) regulation of DNA-templated transcription (3.9%) phosphorelay signal transduction system (3.7%)" "membrane (4.1%) plasma membrane (3.1%) cytosol (1.9%)" "ATP binding (12.3%) DNA binding (4.9%) ADP binding (4.4%)" "IPR027417 (6.8%) IPR003593 (5.1%) IPR000523 (3.8%)" "P-loop containing nucleoside triphosphate hydrolase (6.8%) AAA+ ATPase domain (5.1%) Magnesium chelatase ChlI-like, catalytic domain (3.8%)" YTENMTFEEASK Segatella copri DSM 18205 Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri Segatella copri DSM 18205 LLPTLLSR root "2.7.7.7 (96.9%) 3.6.4.12 (2.2%) 2.5.1.18 (0.2%)" "DNA-directed DNA polymerase (96.9%) DNA helicase (2.2%) glutathione transferase (0.2%)" "GO:0006261 (19.3%) GO:0000727 (0.4%) GO:0006271 (0.4%)" "GO:0009360 (14.7%) GO:0005634 (0.4%) GO:0042555 (0.4%)" "GO:0003887 (16.6%) GO:0003677 (11.9%) GO:0005524 (11.2%)" "DNA-templated DNA replication (19.3%) double-strand break repair via break-induced replication (0.4%) DNA strand elongation involved in DNA replication (0.4%)" "DNA polymerase III complex (14.7%) nucleus (0.4%) MCM complex (0.4%)" "DNA-directed DNA polymerase activity (16.6%) DNA binding (11.9%) ATP binding (11.2%)" "IPR027417 (16.5%) IPR050238 (15.9%) IPR003593 (9%)" "P-loop containing nucleoside triphosphate hydrolase (16.5%) DNA Replication and Repair Clamp Loader Complex (15.9%) AAA+ ATPase domain (9%)" GYDGLLNDELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" GO:0005945 (9.1%) "GO:0003872 (9.1%) GO:0005524 (9.1%) GO:0016208 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" 6-phosphofructokinase complex (9.1%) "6-phosphofructokinase activity (9.1%) ATP binding (9.1%) AMP binding (9.1%)" "IPR000023 (16.7%) IPR012003 (16.7%) IPR012828 (16.7%)" "Phosphofructokinase domain (16.7%) ATP-dependent 6-phosphofructokinase, prokaryotic-type (16.7%) ATP-dependent 6-phosphofructokinase, prokaryotic (16.7%)" FVDVNGDGELSPDDR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LAFGLLAR root "2.5.1.10 (49%) 6.6.1.2 (12.2%) 2.5.1.29 (10.2%)" "(2E,6E)-farnesyl diphosphate synthase (49%) cobaltochelatase (12.2%) geranylgeranyl diphosphate synthase (10.2%)" "GO:0016114 (4.8%) GO:0006508 (1.3%) GO:1903785 (1.3%)" "GO:0005886 (14%) GO:0012505 (8%) GO:0005737 (6.9%)" "GO:0005345 (8%) GO:0046872 (6.3%) GO:0004659 (5%)" "terpenoid biosynthetic process (4.8%) proteolysis (1.3%) L-valine transmembrane transport (1.3%)" "plasma membrane (14%) endomembrane system (8%) cytoplasm (6.9%)" "purine nucleobase transmembrane transporter activity (8%) metal ion binding (6.3%) prenyltransferase activity (5%)" "IPR006043 (7.3%) IPR045018 (7.3%) IPR000092 (5.2%)" "Nucleobase cation symporter 2 family (7.3%) Azaguanine-like transporters (7.3%) Polyprenyl synthetase-like (5.2%)" FVLLAPLHVLEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (17%) IPR004602 (17%) IPR041102 (17%)" "ABC transporter-like, ATP-binding domain (17%) UvrABC system subunit A (17%) UvrA, interaction domain (17%)" SLGLENTDLVEDYLDNVYNTLVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (26.6%) IPR003593 (25%) IPR041682 (25%)" "Domain of unknown function DUF4143 (26.6%) AAA+ ATPase domain (25%) AAA domain, group 14 (25%)" YYGSDGNTTQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000917 (13.9%) GO:0043093 (13.9%) GO:0051258 (13.9%)" "GO:0005737 (13.9%) GO:0032153 (13.9%)" "GO:0005525 (15.3%) GO:0003924 (13.9%)" "division septum assembly (13.9%) FtsZ-dependent cytokinesis (13.9%) protein polymerization (13.9%)" "cytoplasm (13.9%) cell division site (13.9%)" "GTP binding (15.3%) GTPase activity (13.9%)" "IPR024757 (12.6%) IPR000158 (11.5%) IPR003008 (11.5%)" "Cell division protein FtsZ, C-terminal (12.6%) Cell division protein FtsZ (11.5%) Tubulin/FtsZ, GTPase domain (11.5%)" LLFLDRDGTLLQEPEDEQLDSFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.1.3.15 (50%) 4.2.1.19 (50%)" "histidinol-phosphatase (50%) imidazoleglycerol-phosphate dehydratase (50%)" "GO:0000105 (20%) GO:0005975 (0.7%)" GO:0005737 (20%) "GO:0004401 (20%) GO:0004424 (20%) GO:0046872 (19.3%)" "L-histidine biosynthetic process (20%) carbohydrate metabolic process (0.7%)" cytoplasm (20%) "histidinol-phosphatase activity (20%) imidazoleglycerol-phosphate dehydratase activity (20%) metal ion binding (19.3%)" "IPR005954 (10.1%) IPR006543 (10.1%) IPR006549 (10.1%)" "Histidine biosynthesis bifunctional protein, N-terminal histidinol-phosphatase domain (10.1%) Histidinol-phosphate phosphatase (10.1%) HAD-superfamily hydrolase,subfamily IIIA (10.1%)" LTGDVEYFYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR036942 (13.3%) IPR039426 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.3%) TonB-dependent receptor-like (13.3%)" NTYLGEAHALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" GSFNDYAYFAFYQALGNVNSALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SLLLATSK root "2.7.9.1 (44.1%) 2.7.7.7 (20.6%) 2.7.7.6 (8.8%)" "pyruvate, phosphate dikinase (44.1%) DNA-directed DNA polymerase (20.6%) DNA-directed RNA polymerase (8.8%)" "GO:0000278 (2.2%) GO:0006272 (2.2%) GO:0006287 (2.2%)" "GO:0016020 (4.7%) GO:0005737 (2.2%) GO:0005829 (2.2%)" "GO:0005524 (8.2%) GO:0046872 (6.9%) GO:0016301 (4.7%)" "mitotic cell cycle (2.2%) leading strand elongation (2.2%) base-excision repair, gap-filling (2.2%)" "membrane (4.7%) cytoplasm (2.2%) cytosol (2.2%)" "ATP binding (8.2%) metal ion binding (6.9%) kinase activity (4.7%)" "IPR000121 (3.4%) IPR002192 (3.4%) IPR008279 (3.4%)" "PEP-utilising enzyme, C-terminal (3.4%) Pyruvate phosphate dikinase, AMP/ATP-binding (3.4%) PEP-utilising enzyme, mobile domain (3.4%)" GDKVLELFQQLAHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009166 (50%) GO:0016787 (50%) nucleotide catabolic process (50%) hydrolase activity (50%) "IPR006179 (34%) IPR008334 (34%) IPR036907 (32%)" "5'-Nucleotidase/apyrase (34%) 5'-Nucleotidase, C-terminal (34%) 5'-Nucleotidase, C-terminal domain superfamily (32%)" NHGVQFTDDLDKLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.18 (100%) anthranilate phosphoribosyltransferase (100%) GO:0000162 (25.2%) GO:0005829 (25.2%) "GO:0004048 (25.2%) GO:0000287 (24.3%)" L-tryptophan biosynthetic process (25.2%) cytosol (25.2%) "anthranilate phosphoribosyltransferase activity (25.2%) magnesium ion binding (24.3%)" "IPR000312 (20.3%) IPR005940 (20.3%) IPR017459 (20.3%)" "Glycosyl transferase, family 3 (20.3%) Anthranilate phosphoribosyl transferase (20.3%) Glycosyl transferase family 3, N-terminal domain (20.3%)" MLEYLVK root "3.1.3.45 (14.7%) 2.3.2.27 (8.8%) 2.7.2.3 (8.8%)" "3-deoxy-manno-octulosonate-8-phosphatase (14.7%) RING-type E3 ubiquitin transferase (8.8%) phosphoglycerate kinase (8.8%)" "GO:0005975 (10.3%) GO:0034728 (2.1%) GO:0006355 (1.7%)" "GO:0005634 (5.8%) GO:0016020 (3.2%) GO:0005886 (2.7%)" "GO:0004553 (8.3%) GO:0005524 (4.4%) GO:0003677 (2.6%)" "carbohydrate metabolic process (10.3%) nucleosome organization (2.1%) regulation of DNA-templated transcription (1.7%)" "nucleus (5.8%) membrane (3.2%) plasma membrane (2.7%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (8.3%) ATP binding (4.4%) DNA binding (2.6%)" "IPR001764 (5.7%) IPR017853 (5.7%) IPR050288 (5.7%)" "Glycoside hydrolase, family 3, N-terminal (5.7%) Glycoside hydrolase superfamily (5.7%) Cellulose-degrading glycosyl hydrolase 3 (5.7%)" FLFSNSYFSPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.3%) IPR039426 (15.3%) IPR012910 (14.6%)" "TonB-dependent outer membrane protein, SusC/RagA (15.3%) TonB-dependent receptor-like (15.3%) TonB-dependent receptor, plug domain (14.6%)" ELFEGLALADYEKDWVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (40.4%) IPR012547 (32.7%) IPR027417 (26.9%)" "AAA-ATPase-like domain (40.4%) PD-(D/E)XK nuclease superfamily 9 (32.7%) P-loop containing nucleoside triphosphate hydrolase (26.9%)" LSVGLEDVEDLLDDLK Bacteria Bacteria "4.4.1.11 (46.2%) 2.5.1.48 (30.8%) 2.5.1.49 (7.7%)" "methionine gamma-lyase (46.2%) cystathionine gamma-synthase (30.8%) O-acetylhomoserine aminocarboxypropyltransferase (7.7%)" "GO:0019346 (14.8%) GO:0006535 (10.7%) GO:0071269 (10.7%)" GO:0005737 (14.8%) "GO:0030170 (14.8%) GO:0003961 (10.7%) GO:0004124 (10.7%)" "transsulfuration (14.8%) cysteine biosynthetic process from serine (10.7%) L-homocysteine biosynthetic process (10.7%)" cytoplasm (14.8%) "pyridoxal phosphate binding (14.8%) O-acetylhomoserine aminocarboxypropyltransferase activity (10.7%) cysteine synthase activity (10.7%)" "IPR000277 (20%) IPR015422 (20%) IPR015424 (20%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (20%) Pyridoxal phosphate-dependent transferase, small domain (20%) Pyridoxal phosphate-dependent transferase (20%)" LLCLGDTYKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) AKVELAPEDFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (13.2%) GO:0006261 (11.8%)" "GO:0005694 (11.8%) GO:0005737 (11.8%)" "GO:0003677 (13.2%) GO:0005524 (13.2%) GO:0034335 (11.8%)" "DNA topological change (13.2%) DNA-templated DNA replication (11.8%)" "chromosome (11.8%) cytoplasm (11.8%)" "DNA binding (13.2%) ATP binding (13.2%) DNA negative supercoiling activity (11.8%)" "IPR001241 (8.1%) IPR006171 (8.1%) IPR013506 (8.1%)" "DNA topoisomerase, type IIA (8.1%) TOPRIM domain (8.1%) DNA topoisomerase, type IIA, subunit B, domain 2 (8.1%)" FAKEELPFAGELYMGHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (80%) GO:0016740 (20%)" "glycosyltransferase activity (80%) transferase activity (20%)" "IPR000836 (25.8%) IPR017932 (25.8%) IPR029055 (24.2%)" "Phosphoribosyltransferase domain (25.8%) Glutamine amidotransferase type 2 domain (25.8%) Nucleophile aminohydrolases, N-terminal (24.2%)" AYTDLSNLDPTLNYPLDKDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0043093 (33.3%) "GO:0009898 (33.3%) GO:0032153 (33.3%)" FtsZ-dependent cytokinesis (33.3%) "cytoplasmic side of plasma membrane (33.3%) cell division site (33.3%)" "IPR003494 (25%) IPR020823 (25%) IPR043129 (25%)" "SHS2 domain inserted in FtsA (25%) Cell division protein FtsA (25%) ATPase, nucleotide binding domain (25%)" NDDPEHASRPFSASR Bacteria Bacteria 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.4%) IPR014030 (14.4%) IPR020841 (14.4%)" "Beta-ketoacyl synthase (14.4%) Beta-ketoacyl synthase-like, N-terminal (14.4%) Polyketide synthase, beta-ketoacyl synthase domain (14.4%)" ALEQAPDLVASLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) "GO:0000160 (14%) GO:0007234 (11.8%)" GO:0016020 (25%) "GO:0016301 (25.7%) GO:0000156 (11.8%) GO:0030295 (11.8%)" "phosphorelay signal transduction system (14%) osmosensory signaling via phosphorelay pathway (11.8%)" membrane (25%) "kinase activity (25.7%) phosphorelay response regulator activity (11.8%) protein kinase activator activity (11.8%)" "IPR003594 (13%) IPR005467 (13%) IPR033405 (13%)" "Histidine kinase/HSP90-like ATPase domain (13%) Histidine kinase domain (13%) Domain of unknown function DUF5112 (13%)" VLFLNQELDPYVAESHMSLMGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.21 (100%) starch synthase (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR013534 (100%) Starch synthase, catalytic domain (100%) LAPLAAAAK root "2.6.1.- (55.6%) 2.6.1.1 (44.4%)" "Transaminases (55.6%) aspartate transaminase (44.4%)" "GO:0006520 (26.3%) GO:0005975 (0.8%) GO:0006171 (0.8%)" "GO:0005634 (0.8%) GO:0005737 (0.8%) GO:0016020 (0.8%)" "GO:0030170 (26.3%) GO:0008483 (24.8%) GO:0016787 (3%)" "amino acid metabolic process (26.3%) carbohydrate metabolic process (0.8%) cAMP biosynthetic process (0.8%)" "nucleus (0.8%) cytoplasm (0.8%) membrane (0.8%)" "pyridoxal phosphate binding (26.3%) transaminase activity (24.8%) hydrolase activity (3%)" "IPR004839 (16.2%) IPR050596 (16.2%) IPR015421 (15.7%)" "Aminotransferase, class I/classII, large domain (16.2%) Aspartate/prephenate aminotransferase-like (16.2%) Pyridoxal phosphate-dependent transferase, major domain (15.7%)" NELLVNGNHLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (16.7%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (16.7%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" FDFTPEQREEELDWFGNLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032574 (100%) Protein of unknown function DUF4924 (100%) LLNEFGSVEGLLENSSQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006261 (16.3%) GO:0006302 (16.3%) GO:0033567 (0.5%)" "GO:0003677 (16.8%) GO:0008409 (16.8%) GO:0003887 (16.3%)" "DNA-templated DNA replication (16.3%) double-strand break repair (16.3%) DNA replication, Okazaki fragment processing (0.5%)" "DNA binding (16.8%) 5'-3' exonuclease activity (16.8%) DNA-directed DNA polymerase activity (16.3%)" "IPR002421 (8%) IPR008918 (8%) IPR020045 (8%)" "5'-3' exonuclease (8%) Helix-hairpin-helix motif, class 2 (8%) DNA polymerase I-like, H3TH domain (8%)" SNSTELNNLLTAFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006298 (14.8%) GO:0032300 (14.8%) "GO:0005524 (14.8%) GO:0016887 (14.8%) GO:0030983 (14.8%)" mismatch repair (14.8%) mismatch repair complex (14.8%) "ATP binding (14.8%) ATP hydrolysis activity (14.8%) mismatched DNA binding (14.8%)" "IPR002099 (8.6%) IPR014762 (8.6%) IPR038973 (8.6%)" "DNA mismatch repair protein MutL/Mlh/PMS (8.6%) DNA mismatch repair, conserved site (8.6%) DNA mismatch repair protein MutL/Mlh/Pms-like (8.6%)" TLDEADWK root "2.7.13.3 (89.2%) 3.1.4.50 (10.8%)" "histidine kinase (89.2%) glycosylphosphatidylinositol phospholipase D (10.8%)" "GO:0002042 (1.4%) GO:0002430 (1.4%) GO:0006629 (1.4%)" "GO:0034364 (1.9%) GO:0005737 (1.4%) GO:0043231 (1.4%)" "GO:0000155 (16.2%) GO:0005524 (16.2%) GO:0003700 (15.7%)" "cell migration involved in sprouting angiogenesis (1.4%) complement receptor mediated signaling pathway (1.4%) lipid metabolic process (1.4%)" "high-density lipoprotein particle (1.9%) cytoplasm (1.4%) intracellular membrane-bounded organelle (1.4%)" "phosphorelay sensor kinase activity (16.2%) ATP binding (16.2%) DNA-binding transcription factor activity (15.7%)" "IPR001789 (7%) IPR003594 (7%) IPR005467 (7%)" "Signal transduction response regulator, receiver domain (7%) Histidine kinase/HSP90-like ATPase domain (7%) Histidine kinase domain (7%)" EQLEQALKDESLLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011604 (33.3%) IPR027417 (33.3%) IPR038726 (33.3%)" "PD-(D/E)XK endonuclease-like domain superfamily (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) PD-(D/E)XK endonuclease-like domain, AddAB-type (33.3%)" GKNQNEFPWDNADVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0120147 (100%) formylglycine-generating oxidase activity (100%) "IPR005532 (26.1%) IPR051043 (26.1%) IPR016187 (23.9%)" "Sulfatase-modifying factor enzyme-like domain (26.1%) Sulfatase Modifying Factor and Kinase (26.1%) C-type lectin fold (23.9%)" ASETPQVWALYK Pseudomonadati Bacteria Pseudomonadati "GO:0005975 (40.7%) GO:0045493 (3.5%) GO:0006426 (2.7%)" GO:0005737 (2.7%) "GO:0016787 (41.6%) GO:0046559 (3.5%) GO:0004820 (2.7%)" "carbohydrate metabolic process (40.7%) xylan catabolic process (3.5%) glycyl-tRNA aminoacylation (2.7%)" cytoplasm (2.7%) "hydrolase activity (41.6%) alpha-glucuronidase activity (3.5%) glycine-tRNA ligase activity (2.7%)" "IPR031924 (24.4%) IPR041437 (24.4%) IPR029018 (23.5%)" "Glycosyl hydrolase family 115 (24.4%) Gylcosyl hydrolase 115 C-terminal domain (24.4%) Beta-hexosaminidase-like, domain 2 (23.5%)" ADNPDWYFNALAGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (34.5%) IPR050330 (33.6%) IPR036737 (31.8%)" "OmpA-like domain (34.5%) Bacterial Outer Membrane Structural/Functional (33.6%) OmpA-like domain superfamily (31.8%)" VSSYTDFLLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR011630 (100%) Nucleotide modification associated domain 1 (100%) QFDLLVLDDGSPDGTAALVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0009247 (33.3%) GO:0016020 (33.3%) GO:0004582 (33.3%) glycolipid biosynthetic process (33.3%) membrane (33.3%) dolichyl-phosphate beta-D-mannosyltransferase activity (33.3%) "IPR001173 (35%) IPR039528 (35%) IPR029044 (30%)" "Glycosyltransferase 2-like (35%) DPM1-like (35%) Nucleotide-diphospho-sugar transferases (30%)" ENAGGLLR root "1.3.98.3 (30%) 2.7.13.3 (20%) 2.5.1.73 (10%)" "coproporphyrinogen dehydrogenase (30%) histidine kinase (20%) O-phospho-L-seryl-tRNA:Cys-tRNA synthase (10%)" "GO:0090090 (7.2%) GO:0001708 (7.2%) GO:0007026 (7.2%)" "GO:0016342 (7.2%) GO:0030877 (7.2%) GO:0005881 (7.1%)" "GO:0008013 (7.3%) GO:0008017 (7.2%) GO:0016639 (0.8%)" "negative regulation of canonical Wnt signaling pathway (7.2%) cell fate specification (7.2%) negative regulation of microtubule depolymerization (7.2%)" "catenin complex (7.2%) beta-catenin destruction complex (7.2%) cytoplasmic microtubule (7.1%)" "beta-catenin binding (7.3%) microtubule binding (7.2%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (0.8%)" "IPR000225 (13.5%) IPR026818 (13.5%) IPR011989 (13.4%)" "Armadillo (13.5%) Adenomatous polyposis coli (APC) family (13.5%) Armadillo-like helical (13.4%)" YAAQSLDVGANVNFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" LLNFPAVYDMLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.99.- (100%) With other acceptors (100%) "GO:0016627 (50.5%) GO:0050660 (49.5%)" "oxidoreductase activity, acting on the CH-CH group of donors (50.5%) flavin adenine dinucleotide binding (49.5%)" "IPR009075 (10.2%) IPR020964 (10.2%) IPR052166 (10.2%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10.2%) Acyl-CoA dehydrogenase, C-terminal (10.2%) Diverse substrate specificity acyl-CoA dehydrogenase (10.2%)" NLGGDPENAFVLFDDVKELYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.1 (100%) transketolase (100%) GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005474 (12.5%) IPR005475 (12.5%) IPR009014 (12.5%)" "Transketolase, N-terminal (12.5%) Transketolase-like, pyrimidine-binding domain (12.5%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.5%)" LYEGEFVTLMGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) GO:0005886 (12.5%) "GO:0005524 (37.5%) GO:0016887 (37.5%) GO:0022857 (12.5%)" plasma membrane (12.5%) "ATP binding (37.5%) ATP hydrolysis activity (37.5%) transmembrane transporter activity (12.5%)" "IPR003439 (19.2%) IPR003593 (18.6%) IPR017871 (18.6%)" "ABC transporter-like, ATP-binding domain (19.2%) AAA+ ATPase domain (18.6%) ABC transporter-like, conserved site (18.6%)" CLDELAHNMWWAWNYEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" KLDEFAEFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.182 (100%) lipid-A-disaccharide synthase (100%) GO:0009245 (25%) GO:0016020 (25%) "GO:0005543 (25%) GO:0008915 (25%)" lipid A biosynthetic process (25%) membrane (25%) "phospholipid binding (25%) lipid-A-disaccharide synthase activity (25%)" IPR003835 (100%) Glycosyl transferase, family 19 (100%) LVEEFMLLANR root "3.1.13.- (52.6%) 3.1.13.1 (47.2%) 3.1.-.- (0.3%)" "Exoribonucleases producing 5'-phosphomonoesters (52.6%) exoribonuclease II (47.2%) Acting on ester bonds (0.3%)" "GO:0006402 (10.9%) GO:0000956 (9.5%) GO:1990074 (9.5%)" "GO:0000932 (10.6%) GO:0005829 (9.1%) GO:0016020 (0.1%)" "GO:0003723 (19.9%) GO:0000175 (10.6%) GO:0046872 (9.7%)" "mRNA catabolic process (10.9%) nuclear-transcribed mRNA catabolic process (9.5%) polyuridylation-dependent mRNA catabolic process (9.5%)" "P-body (10.6%) cytosol (9.1%) membrane (0.1%)" "RNA binding (19.9%) 3'-5'-RNA exonuclease activity (10.6%) metal ion binding (9.7%)" "IPR001900 (14.5%) IPR050180 (14.4%) IPR012340 (14.3%)" "Ribonuclease II/R (14.5%) RNR Ribonuclease (14.4%) Nucleic acid-binding, OB-fold (14.3%)" LSTSDLDEVLLVGGSSR Pseudomonadati Bacteria Pseudomonadati GO:0005737 (0.5%) "GO:0005524 (33.7%) GO:0140662 (33.7%) GO:0051082 (32.2%)" cytoplasm (0.5%) "ATP binding (33.7%) ATP-dependent protein folding chaperone (33.7%) unfolded protein binding (32.2%)" "IPR013126 (17%) IPR018181 (17%) IPR043129 (17%)" "Heat shock protein 70 family (17%) Heat shock protein 70, conserved site (17%) ATPase, nucleotide binding domain (17%)" DYSEFTFK root "GO:0042060 (20%) GO:0045104 (20%)" "GO:0005737 (20%) GO:0016020 (20%)" GO:0005198 (20%) "wound healing (20%) intermediate filament cytoskeleton organization (20%)" "cytoplasm (20%) membrane (20%)" structural molecule activity (20%) "IPR001715 (16.7%) IPR002017 (16.7%) IPR018159 (16.7%)" "Calponin homology domain (16.7%) Spectrin repeat (16.7%) Spectrin/alpha-actinin (16.7%)" SNNSYFGGLAAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0016020 (15.4%) GO:0005886 (4.6%)" "GO:0048038 (20%) GO:0051539 (20%) GO:0016651 (15.4%)" "membrane (15.4%) plasma membrane (4.6%)" "quinone binding (20%) 4 iron, 4 sulfur cluster binding (20%) oxidoreductase activity, acting on NAD(P)H (15.4%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" APNVSQLAEELNTSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR036390 (34.2%) IPR041682 (34.2%) IPR027417 (31.6%)" "Winged helix DNA-binding domain superfamily (34.2%) AAA domain, group 14 (34.2%) P-loop containing nucleoside triphosphate hydrolase (31.6%)" MQGLDADKVYTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.5%) IPR013780 (12.5%) IPR013785 (12.5%)" "Glycoside hydrolase family 36 (12.5%) Glycosyl hydrolase, all-beta (12.5%) Aldolase-type TIM barrel (12.5%)" LQDSLTYFLTSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.1.32 (100%) phospholipase A1 (100%) GO:0016020 (49.6%) "GO:0046873 (49.6%) GO:0008970 (0.7%)" membrane (49.6%) "metal ion transmembrane transporter activity (49.6%) phospholipase A1 activity (0.7%)" "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" DGPVLNLK root "3.4.16.- (75%) 7.2.2.10 (25%)" "Serine-type carboxypeptidases (75%) P-type Ca(2+) transporter (25%)" "GO:0044205 (11.7%) GO:0006508 (3.7%) GO:0005980 (1.2%)" "GO:0016020 (1.9%) GO:0005737 (0.6%) GO:0005794 (0.6%)" "GO:0016491 (12.3%) GO:0009055 (11.7%) GO:0046872 (11.7%)" "'de novo' UMP biosynthetic process (11.7%) proteolysis (3.7%) glycogen catabolic process (1.2%)" "membrane (1.9%) cytoplasm (0.6%) Golgi apparatus (0.6%)" "oxidoreductase activity (12.3%) electron transfer activity (11.7%) metal ion binding (11.7%)" "IPR019480 (7.6%) IPR050353 (7.6%) IPR001433 (7.2%)" "Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (7.6%) Dihydroorotate dehydrogenase B electron transfer subunit (7.6%) Oxidoreductase FAD/NAD(P)-binding (7.2%)" ASYGEAGQSSTGAGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.6%) IPR023996 (14.6%) IPR023997 (14.6%)" "TonB-dependent receptor, plug domain (14.6%) TonB-dependent outer membrane protein, SusC/RagA (14.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.6%)" VHGNMPAMTGTTQAEVQAQLEHER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.2%) IPR012944 (34.2%) IPR033985 (31.6%)" "Tetratricopeptide-like helical domain superfamily (34.2%) RagB/SusD domain (34.2%) SusD-like, N-terminal (31.6%)" NNSAVQLLMDPNKQTLNADNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" VYQNLAFEPVAFMQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.1%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.1%)" "IPR004199 (6.8%) IPR006102 (6.8%) IPR006103 (6.8%)" "Beta galactosidase small chain/ domain 5 (6.8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.8%) Glycoside hydrolase family 2, catalytic domain (6.8%)" NALALQQLVSNLLDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19.4%) "GO:0000155 (20.6%) GO:0003700 (20%) GO:0005524 (20%)" membrane (19.4%) "phosphorelay sensor kinase activity (20.6%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR003594 (8%) IPR003661 (8%) IPR001789 (7.7%)" "Histidine kinase/HSP90-like ATPase domain (8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (8%) Signal transduction response regulator, receiver domain (7.7%)" FEVVADAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.3%) IPR008147 (14.3%) IPR014746 (14.3%)" "Glutamine synthetase, catalytic domain (14.3%) Glutamine synthetase, N-terminal domain (14.3%) Glutamine synthetase/guanido kinase, catalytic domain (14.3%)" FTLQNADPNAVLTFSYLGCKPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" LLDDLVNSYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (100%) cell division (100%) "IPR007838 (55.6%) IPR036192 (44.4%)" "Cell division protein ZapA-like (55.6%) Cell division protein ZapA-like superfamily (44.4%)" GQELPMLK root "2.4.1.227 (88.2%) 1.2.1.38 (5.9%) 2.4.-.- (5.9%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (88.2%) N-acetyl-gamma-glutamyl-phosphate reductase (5.9%) Glycosyltransferases (5.9%)" "GO:0005975 (11.8%) GO:0008360 (11.8%) GO:0009252 (11.8%)" "GO:0005886 (11.8%) GO:0005634 (1.6%)" "GO:0050511 (11.8%) GO:0046983 (1.6%) GO:0016758 (0.8%)" "carbohydrate metabolic process (11.8%) regulation of cell shape (11.8%) peptidoglycan biosynthetic process (11.8%)" "plasma membrane (11.8%) nucleus (1.6%)" "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.8%) protein dimerization activity (1.6%) hexosyltransferase activity (0.8%)" "IPR007235 (30.8%) IPR004276 (28.8%) IPR006009 (28.8%)" "Glycosyl transferase, family 28, C-terminal (30.8%) Glycosyltransferase family 28, N-terminal domain (28.8%) N-acetylglucosaminyltransferase, MurG (28.8%)" HYDFSCLLTSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR035986 (100%) PKD domain superfamily (100%) KQLLEHTPDLVLNVLDTSNLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25.2%) "GO:0005525 (25.2%) GO:0015093 (25.2%) GO:0046914 (24.5%)" plasma membrane (25.2%) "GTP binding (25.2%) ferrous iron transmembrane transporter activity (25.2%) transition metal ion binding (24.5%)" "IPR005225 (9.3%) IPR030389 (9.3%) IPR050860 (9.3%)" "Small GTP-binding domain (9.3%) FeoB-type guanine nucleotide-binding (G) domain (9.3%) Fe(2+) Transporter FeoB GTPase (9.3%)" QAALQQALEYFEAVTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (33.3%) IPR027417 (33.3%) IPR041682 (33.3%)" "Domain of unknown function DUF4143 (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) AAA domain, group 14 (33.3%)" HLVEMEYYVDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR041246 (20.3%) IPR001599 (18.6%) IPR002890 (18.6%)" "Bacterial alpha-2-macroglobulin MG10 domain (20.3%) Alpha-2-macroglobulin (18.6%) Macroglobulin domain (18.6%)" TQGVWNSQEELDANPHFADDVPGGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" WASFPSVALGWR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.6%) IPR023996 (13.6%) IPR023997 (13.6%)" "TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.6%)" AFEASDLDFSELYGCLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005840 (50%) GO:1990904 (50%)" "ribosome (50%) ribonucleoprotein complex (50%)" "IPR001790 (33.3%) IPR043141 (33.3%) IPR047865 (33.3%)" "Large ribosomal subunit protein uL10 (33.3%) Large ribosomal subunit protein uL10-like domain superfamily (33.3%) Large ribosomal subunit protein uL10, bacteria/organella (33.3%)" DVVDYELTEEGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR040572 (100%) Thaumarchaeal output domain 1 (100%) ENLPLLPEK root 3.6.1.22 (100%) NAD(+) diphosphatase (100%) "GO:0006734 (16.5%) GO:0006742 (16.5%) GO:0019677 (16.5%)" GO:0005829 (16.5%) "GO:0035529 (16.5%) GO:0046872 (16.5%) GO:0110153 (0.9%)" "obsolete NADH metabolic process (16.5%) NADP+ catabolic process (16.5%) NAD+ catabolic process (16.5%)" cytosol (16.5%) "NADH pyrophosphatase activity (16.5%) metal ion binding (16.5%) RNA NAD-cap (NMN-forming) hydrolase activity (0.9%)" "IPR000086 (14.5%) IPR015375 (14.5%) IPR015376 (14.5%)" "NUDIX hydrolase domain (14.5%) NADH pyrophosphatase-like, N-terminal (14.5%) Zinc ribbon, NADH pyrophosphatase (14.5%)" TVFGLAEYNYLLASGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" FGFELFR root 2.3.1.20 (100%) diacylglycerol O-acyltransferase (100%) "GO:0006508 (1.9%) GO:0007015 (1.9%) GO:0035443 (1.9%)" "GO:0016020 (11.5%) GO:0005886 (9.6%) GO:0012505 (2.9%)" "GO:0022857 (9.6%) GO:0005227 (3.8%) GO:0003676 (2.9%)" "proteolysis (1.9%) actin filament organization (1.9%) tripeptide transmembrane transport (1.9%)" "membrane (11.5%) plasma membrane (9.6%) endomembrane system (2.9%)" "transmembrane transporter activity (9.6%) calcium-activated cation channel activity (3.8%) nucleic acid binding (2.9%)" "IPR043741 (33.5%) IPR036259 (5%) IPR011701 (4.1%)" "Family of unknown function DUF5686 (33.5%) MFS transporter superfamily (5%) Major facilitator superfamily (4.1%)" MAYDAGVFLNPVLPPACAPQDTLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030170 (49.2%) GO:0008483 (31.1%) GO:0016740 (18%)" "pyridoxal phosphate binding (49.2%) transaminase activity (31.1%) transferase activity (18%)" "IPR001917 (16.8%) IPR004839 (16.8%) IPR015422 (16.8%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.8%) Aminotransferase, class I/classII, large domain (16.8%) Pyridoxal phosphate-dependent transferase, small domain (16.8%)" GYYYVPHVVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.16.4 (96%) 2.4.1.129 (4%)" "serine-type D-Ala-D-Ala carboxypeptidase (96%) Transferred entry: 2.4.99.28 (4%)" "GO:0009252 (14.3%) GO:0071555 (14.3%) GO:0008360 (14%)" GO:0005886 (14.3%) "GO:0008658 (14.3%) GO:0071972 (14.3%) GO:0009002 (14%)" "peptidoglycan biosynthetic process (14.3%) cell wall organization (14.3%) regulation of cell shape (14%)" plasma membrane (14.3%) "penicillin binding (14.3%) peptidoglycan L,D-transpeptidase activity (14.3%) serine-type D-Ala-D-Ala carboxypeptidase activity (14%)" "IPR001460 (16.8%) IPR005311 (16.8%) IPR050515 (16.8%)" "Penicillin-binding protein, transpeptidase (16.8%) Penicillin-binding protein, dimerisation domain (16.8%) Class D beta-lactamase/transpeptidase (16.8%)" DKFASNTQLLQVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0043165 (50%) GO:0019867 (50%) Gram-negative-bacterium-type cell outer membrane assembly (50%) outer membrane (50%) IPR007485 (100%) LPS-assembly lipoprotein LptE (100%) ELFEGLK root "2.6.1.42 (94.8%) 6.1.1.20 (0.7%) 2.4.1.241 (0.6%)" "branched-chain-amino-acid transaminase (94.8%) phenylalanine--tRNA ligase (0.7%) digalactosyldiacylglycerol synthase (0.6%)" "GO:0009099 (13.7%) GO:0009098 (13.7%) GO:0009097 (10.5%)" "GO:0005739 (3.2%) GO:0005737 (1.1%) GO:0005829 (0.6%)" "GO:0004084 (9.1%) GO:0052654 (8%) GO:0052655 (8%)" "L-valine biosynthetic process (13.7%) L-leucine biosynthetic process (13.7%) isoleucine biosynthetic process (10.5%)" "mitochondrion (3.2%) cytoplasm (1.1%) cytosol (0.6%)" "branched-chain-amino-acid transaminase activity (9.1%) L-leucine-2-oxoglutarate transaminase activity (8%) L-valine-2-oxoglutarate transaminase activity (8%)" "IPR005786 (12.5%) IPR036038 (12.5%) IPR043131 (12.5%)" "Branched-chain amino acid aminotransferase II (12.5%) Aminotransferase-like, PLP-dependent enzymes (12.5%) Branched-chain-amino-acid aminotransferase-like, N-terminal (12.5%)" NYSFHDDFVETMLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) GO:0006265 (20%) "GO:0003677 (20%) GO:0003918 (20%) GO:0005524 (20%)" DNA topological change (20%) "DNA binding (20%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (20%) ATP binding (20%)" "IPR001241 (9.3%) IPR003594 (9.3%) IPR006171 (9.3%)" "DNA topoisomerase, type IIA (9.3%) Histidine kinase/HSP90-like ATPase domain (9.3%) TOPRIM domain (9.3%)" ETGLEGLSPEDLQSLQVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (20%) GO:0009279 (80%) iron ion transport (20%) cell outer membrane (80%) "IPR012910 (13%) IPR023996 (13%) IPR023997 (13%)" "TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13%)" ELDLPETLEEFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008234 (50%) proteolysis (50%) cysteine-type peptidase activity (50%) "IPR000200 (16.9%) IPR026906 (16.9%) IPR032675 (16.9%)" "Peptidase C10, streptopain (16.9%) BspA-type LRR region (16.9%) Leucine-rich repeat domain superfamily (16.9%)" YWGAFLDTDNEPLFASVDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (43.2%) IPR011990 (37.8%) IPR050498 (18.9%)" "Tetratricopeptide repeat (43.2%) Tetratricopeptide-like helical domain superfamily (37.8%) Photosystem I assembly protein Ycf3 (18.9%)" MSALVDQLVWLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.11 (100%) glutamate 5-kinase (100%) GO:0055129 (23.1%) GO:0005829 (23.1%) "GO:0004349 (23.1%) GO:0005524 (23.1%) GO:0003723 (7.7%)" L-proline biosynthetic process (23.1%) cytosol (23.1%) "glutamate 5-kinase activity (23.1%) ATP binding (23.1%) RNA binding (7.7%)" "IPR001048 (14.2%) IPR005715 (14.2%) IPR041739 (14.2%)" "Aspartate/glutamate/uridylate kinase (14.2%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (14.2%) Glutamate-5-kinase domain (14.2%)" KEVVFQHYENR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.4%) IPR024742 (20.4%) IPR032790 (20.4%)" "Glycogen debranching enzyme (20.4%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.4%) Glycogen debranching enzyme, C-terminal (20.4%)" LLSSDLATHLSGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR025420 (33.3%) IPR027417 (33.3%) IPR041682 (33.3%)" "Domain of unknown function DUF4143 (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) AAA domain, group 14 (33.3%)" NPSLFNPVRYPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.- (40%) 3.4.-.- (40%) 2.4.99.28 (20%)" "Hexosyltransferases (40%) Acting on peptide bonds (peptidases) (40%) peptidoglycan glycosyltransferase (20%)" "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (11%) GO:0016020 (0.2%)" "GO:0008955 (11.2%) GO:0008658 (11%) GO:0004180 (10.8%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (11%) membrane (0.2%)" "peptidoglycan glycosyltransferase activity (11.2%) penicillin binding (11%) carboxypeptidase activity (10.8%)" "IPR001264 (17%) IPR050396 (17%) IPR001460 (16.6%)" "Glycosyl transferase, family 51 (17%) Glycosyltransferase 51/Transpeptidase (17%) Penicillin-binding protein, transpeptidase (16.6%)" SATLEFSYLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NLPLSDAYQAMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (96.9%) GO:0046555 (3.1%)" "hydrolase activity (96.9%) acetylxylan esterase activity (3.1%)" "IPR013094 (32.7%) IPR050300 (32.7%) IPR029058 (31.6%)" "Alpha/beta hydrolase fold-3 (32.7%) GDXG lipolytic enzyme (32.7%) Alpha/Beta hydrolase fold (31.6%)" TLNTFATR root GO:0007018 (10%) "GO:0005858 (10%) GO:0005874 (10%)" "GO:0003995 (20%) GO:0050660 (20%) GO:0005524 (10%)" microtubule-based movement (10%) "axonemal dynein complex (10%) microtubule (10%)" "acyl-CoA dehydrogenase activity (20%) flavin adenine dinucleotide binding (20%) ATP binding (10%)" "IPR006089 (7.1%) IPR006091 (7.1%) IPR009075 (7.1%)" "Acyl-CoA dehydrogenase, conserved site (7.1%) Acyl-CoA oxidase/dehydrogenase, middle domain (7.1%) Acyl-CoA dehydrogenase/oxidase, C-terminal (7.1%)" LGLDNVNEELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.9%) GO:0005737 (24.9%) "GO:0004821 (24.9%) GO:0005524 (24.9%) GO:0004812 (0.4%)" histidyl-tRNA aminoacylation (24.9%) cytoplasm (24.9%) "histidine-tRNA ligase activity (24.9%) ATP binding (24.9%) aminoacyl-tRNA ligase activity (0.4%)" "IPR041715 (12.8%) IPR004154 (12.6%) IPR006195 (12.6%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.8%) Anticodon-binding (12.6%) Aminoacyl-tRNA synthetase, class II (12.6%)" ELEDAELVLYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR025393 (51.3%) IPR029044 (48.7%)" "Domain of unknown function DUF4301 (51.3%) Nucleotide-diphospho-sugar transferases (48.7%)" LEGAELVGK root "1.8.1.8 (40%) 3.1.3.1 (40%) 6.1.1.4 (20%)" "protein-disulfide reductase (40%) alkaline phosphatase (40%) leucine--tRNA ligase (20%)" "GO:0017004 (21.3%) GO:0045454 (21.3%) GO:0006429 (1.1%)" "GO:0005886 (18%) GO:0016020 (3.4%) GO:0005737 (1.1%)" "GO:0015035 (19.1%) GO:0004035 (4.5%) GO:0046872 (4.5%)" "cytochrome complex assembly (21.3%) cell redox homeostasis (21.3%) leucyl-tRNA aminoacylation (1.1%)" "plasma membrane (18%) membrane (3.4%) cytoplasm (1.1%)" "protein-disulfide reductase activity (19.1%) alkaline phosphatase activity (4.5%) metal ion binding (4.5%)" "IPR028250 (19.4%) IPR003834 (18.4%) IPR013766 (16.5%)" "Thiol:disulfide interchange protein DsbD, N-terminal domain (19.4%) Cytochrome C biogenesis protein, transmembrane domain (18.4%) Thioredoxin domain (16.5%)" QMSLLFDVNAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" LDKPGHSYESLNEMLDHVEGLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.11 (100%) serine--tRNA ligase (100%) GO:0006434 (25%) GO:0005737 (25%) "GO:0004828 (25%) GO:0005524 (25%)" seryl-tRNA aminoacylation (25%) cytoplasm (25%) "serine-tRNA ligase activity (25%) ATP binding (25%)" "IPR002314 (14.3%) IPR002317 (14.3%) IPR006195 (14.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (14.3%) Serine-tRNA ligase, type1 (14.3%) Aminoacyl-tRNA synthetase, class II (14.3%)" DLVAEADELKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.8 (100%) mannonate dehydratase (100%) GO:0042840 (25%) "GO:0008198 (25%) GO:0008927 (25%) GO:0030145 (25%)" D-glucuronate catabolic process (25%) "ferrous iron binding (25%) mannonate dehydratase activity (25%) manganese ion binding (25%)" "IPR004628 (51.3%) IPR036237 (48.7%)" "Mannonate dehydratase (51.3%) Xylose isomerase-like superfamily (48.7%)" HLLDMLK root "6.1.1.16 (37.8%) 2.3.2.26 (14.2%) 5.1.99.6 (6.8%)" "cysteine--tRNA ligase (37.8%) HECT-type E3 ubiquitin transferase (14.2%) NAD(P)H-hydrate epimerase (6.8%)" "GO:0006351 (2.6%) GO:0006423 (2.4%) GO:0006508 (2.4%)" "GO:0005737 (3.9%) GO:0016020 (3.5%) GO:0019028 (2.2%)" "GO:0005524 (6.9%) GO:0046872 (3.6%) GO:0003723 (2.7%)" "DNA-templated transcription (2.6%) cysteinyl-tRNA aminoacylation (2.4%) proteolysis (2.4%)" "cytoplasm (3.9%) membrane (3.5%) viral capsid (2.2%)" "ATP binding (6.9%) metal ion binding (3.6%) RNA binding (2.7%)" "IPR027417 (2.6%) IPR014729 (2%) IPR015803 (2%)" "P-loop containing nucleoside triphosphate hydrolase (2.6%) Rossmann-like alpha/beta/alpha sandwich fold (2%) Cysteine-tRNA ligase (2%)" WWGVSMQDFNAVGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (17.2%) IPR051795 (17.2%) IPR006710 (16.7%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (17.2%) Glycosyl Hydrolase Family 43 (17.2%) Glycoside hydrolase, family 43 (16.7%)" FYAFVEK root "1.5.1.20 (33.3%) 2.1.1.72 (33.3%) 6.3.5.4 (33.3%)" "methylenetetrahydrofolate reductase [NAD(P)H] (33.3%) site-specific DNA-methyltransferase (adenine-specific) (33.3%) asparagine synthase (glutamine-hydrolyzing) (33.3%)" "GO:0009086 (16%) GO:0035999 (16%) GO:0007165 (1.5%)" "GO:0005829 (16.8%) GO:0016020 (2.3%) GO:0000145 (0.8%)" "GO:0071949 (16%) GO:0004489 (14.5%) GO:0106312 (1.5%)" "methionine biosynthetic process (16%) tetrahydrofolate interconversion (16%) signal transduction (1.5%)" "cytosol (16.8%) membrane (2.3%) exocyst (0.8%)" "FAD binding (16%) methylenetetrahydrofolate reductase [NAD(P)H] activity (14.5%) methylenetetrahydrofolate reductase (NADH) activity (1.5%)" "IPR003171 (24.4%) IPR029041 (22.1%) IPR029168 (3.5%)" "Methylenetetrahydrofolate reductase-like, catalytic domain (24.4%) FAD-linked oxidoreductase-like (22.1%) Meiotic recombination protein REC114-like (3.5%)" QQLKENVQFLATR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FGFPVFVVLDETGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013766 (20.8%) IPR004879 (20.1%) IPR012336 (19.4%)" "Thioredoxin domain (20.8%) Spermatogenesis-associated protein 20-like, TRX domain (20.1%) Thioredoxin-like fold (19.4%)" DLLKENSFR Pseudomonadati Bacteria Pseudomonadati "IPR027417 (25%) IPR034139 (25%) IPR041685 (25%)" "P-loop containing nucleoside triphosphate hydrolase (25%) OLD protein-like, TOPRIM domain (25%) Endonuclease GajA/Old nuclease/RecF-like, AAA domain (25%)" HLLLVPCETPAELWHAQWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SSLAFDTLYAEGQR root "3.1.25.- (99.9%) 3.6.1.3 (0.1%)" "Site-specific endodeoxyribonucleases specific for altered bases (99.9%) Deleted entry (0.1%)" "GO:0006289 (11.2%) GO:0009432 (8.4%) GO:0006281 (0.4%)" "GO:0005737 (11.5%) GO:0009380 (11.2%) GO:0005886 (0.1%)" "GO:0003677 (11.5%) GO:0005524 (11.5%) GO:0008270 (11.3%)" "nucleotide-excision repair (11.2%) SOS response (8.4%) DNA repair (0.4%)" "cytoplasm (11.5%) excinuclease repair complex (11.2%) plasma membrane (0.1%)" "DNA binding (11.5%) ATP binding (11.5%) zinc ion binding (11.3%)" "IPR027417 (14.7%) IPR041102 (14.6%) IPR041552 (14.4%)" "P-loop containing nucleoside triphosphate hydrolase (14.7%) UvrA, interaction domain (14.6%) UvrA DNA-binding domain (14.4%)" VTTSAPLPMMTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ALGDYLLVGVTSDTFDRER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000166 (50%) GO:0016779 (50%)" "nucleotide binding (50%) nucleotidyltransferase activity (50%)" "IPR000683 (20.4%) IPR004821 (20.4%) IPR050385 (20.4%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (20.4%) Cytidyltransferase-like domain (20.4%) Archaeal FAD synthase (20.4%)" ELGFANYVAPNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.8%) GO:0009279 (36.4%) GO:0015344 (31.8%) siderophore transmembrane transport (31.8%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (31.8%) "IPR057601 (23.5%) IPR036942 (20.6%) IPR039426 (20.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (23.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.6%) TonB-dependent receptor-like (20.6%)" SHYGASFYDVLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (50%) GO:0016788 (50%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (50%)" "IPR000801 (16.7%) IPR005181 (16.7%) IPR013783 (16.7%)" "Esterase-like (16.7%) Sialate O-acetylesterase domain (16.7%) Immunoglobulin-like fold (16.7%)" EGFDQLFELAHLLHGEVGASR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (16.7%) IPR014729 (16.7%) IPR014730 (16.7%)" "Electron transfer flavoprotein alpha subunit/FixB (16.7%) Rossmann-like alpha/beta/alpha sandwich fold (16.7%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (16.7%)" LLDAWNTNNTGSSLPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YSLPLLPLK root GO:0009306 (50%) GO:0005886 (50%) protein secretion (50%) plasma membrane (50%) IPR007452 (100%) Translocation and assembly module TamB, C-terminal domain (100%) LPASLTLAQGLFESAAGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0031640 (32.8%) GO:0042742 (32.8%)" GO:0004040 (34.5%) "killing of cells of another organism (32.8%) defense response to bacterium (32.8%)" amidase activity (34.5%) "IPR002901 (25.3%) IPR018392 (25.3%) IPR051056 (25.3%)" "Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain (25.3%) LysM domain (25.3%) Glycosyl Hydrolase Family 73 (25.3%)" TDFGGDVYALLSTPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.6%) "GO:0000155 (26.2%) GO:0003700 (24.6%) GO:0043565 (24.6%)" membrane (24.6%) "phosphorelay sensor kinase activity (26.2%) DNA-binding transcription factor activity (24.6%) sequence-specific DNA binding (24.6%)" "IPR011110 (15.8%) IPR015943 (14.9%) IPR011123 (14.4%)" "Two component regulator propeller (15.8%) WD40/YVTN repeat-like-containing domain superfamily (14.9%) Two component regulator three Y (14.4%)" YGEMNLSAQDCCVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006811 (12.9%) "GO:0009279 (58.1%) GO:0046930 (12.9%) GO:0016020 (3.2%)" GO:0015288 (12.9%) monoatomic ion transport (12.9%) "cell outer membrane (58.1%) pore complex (12.9%) membrane (3.2%)" porin activity (12.9%) "IPR011250 (26.8%) IPR006665 (17%) IPR050330 (17%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (26.8%) OmpA-like domain (17%) Bacterial Outer Membrane Structural/Functional (17%)" EDGAPLQPNDDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.7%) GO:0005829 (32.7%) "GO:0008926 (32.7%) GO:0009026 (1.9%)" mannitol catabolic process (32.7%) cytosol (32.7%) "mannitol-1-phosphate 5-dehydrogenase activity (32.7%) tagaturonate reductase activity (1.9%)" "IPR013118 (21.5%) IPR013131 (21.5%) IPR008927 (19%)" "Mannitol dehydrogenase, C-terminal (21.5%) Mannitol dehydrogenase, N-terminal (21.5%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (19%)" EYVVFNPDLVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QCFNERPVSTQQTGFVFVSQMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) AVYYGQLEDLRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.4.16 (100%) thiamine-phosphate kinase (100%) "GO:0009228 (20%) GO:0009229 (20%)" "GO:0000287 (20%) GO:0005524 (20%) GO:0009030 (20%)" "thiamine biosynthetic process (20%) thiamine diphosphate biosynthetic process (20%)" "magnesium ion binding (20%) ATP binding (20%) thiamine-phosphate kinase activity (20%)" "IPR006283 (23.5%) IPR016188 (23.5%) IPR036676 (21.6%)" "Thiamine-monophosphate kinase-like (23.5%) PurM-like, N-terminal domain (23.5%) PurM-like, C-terminal domain superfamily (21.6%)" ALVNNPAVLLADEATGNLDTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.3.- (95.2%) 3.6.3.28 (4.8%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (95.2%) Transferred entry: 7.3.2.2 (4.8%)" GO:0055085 (0.2%) GO:0005886 (22.5%) "GO:0005524 (27.5%) GO:0016887 (27.4%) GO:0022857 (22.5%)" transmembrane transport (0.2%) plasma membrane (22.5%) "ATP binding (27.5%) ATP hydrolysis activity (27.4%) transmembrane transporter activity (22.5%)" "IPR003439 (17.3%) IPR017871 (17.2%) IPR027417 (17.2%)" "ABC transporter-like, ATP-binding domain (17.3%) ABC transporter-like, conserved site (17.2%) P-loop containing nucleoside triphosphate hydrolase (17.2%)" QQSVSVLTYLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.6%) "GO:0005524 (20.7%) GO:0016881 (20.7%) GO:0008784 (19.6%)" D-alanine biosynthetic process (19.6%) "ATP binding (20.7%) acid-amino acid ligase activity (20.7%) alanine racemase activity (19.6%)" "IPR051046 (10.6%) IPR001608 (10.3%) IPR013221 (10.3%)" "MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.6%) Alanine racemase, N-terminal (10.3%) Mur ligase, central (10.3%)" YVDLLGR root "3.5.1.98 (13.5%) 2.7.13.3 (12.2%) 3.2.1.78 (12.2%)" "histone deacetylase (13.5%) histidine kinase (12.2%) mannan endo-1,4-beta-mannosidase (12.2%)" "GO:0006080 (5.1%) GO:0009451 (4.5%) GO:0006355 (4.3%)" "GO:0005829 (4.9%) GO:0032993 (4.2%) GO:0016020 (3.1%)" "GO:0016985 (5.1%) GO:0003723 (4.3%) GO:0000156 (4.2%)" "substituted mannan metabolic process (5.1%) RNA modification (4.5%) regulation of DNA-templated transcription (4.3%)" "cytosol (4.9%) protein-DNA complex (4.2%) membrane (3.1%)" "mannan endo-1,4-beta-mannosidase activity (5.1%) RNA binding (4.3%) phosphorelay response regulator activity (4.2%)" "IPR022790 (3.7%) IPR017853 (3.6%) IPR000805 (3.4%)" "Glycosyl hydrolase family 26 domain (3.7%) Glycoside hydrolase superfamily (3.6%) Glycoside hydrolase family 26 (3.4%)" GFGLNVADSLLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (15.3%) GO:0008360 (12.9%) GO:0009252 (12.9%)" GO:0005737 (12.9%) "GO:0005524 (15.3%) GO:0008716 (15.3%) GO:0046872 (15.3%)" "cell wall organization (15.3%) regulation of cell shape (12.9%) peptidoglycan biosynthetic process (12.9%)" cytoplasm (12.9%) "ATP binding (15.3%) D-alanine-D-alanine ligase activity (15.3%) metal ion binding (15.3%)" "IPR000291 (14.6%) IPR005905 (14.6%) IPR011095 (14.6%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.6%) D-alanine--D-alanine ligase (14.6%) D-alanine--D-alanine ligase, C-terminal (14.6%)" KVNVDAGALMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MGTLLHNLFSTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.4%) GO:0005829 (16.4%) "GO:0003677 (16.4%) GO:0004527 (16.4%) GO:0005524 (16.4%)" recombinational repair (16.4%) cytosol (16.4%) "DNA binding (16.4%) exonuclease activity (16.4%) ATP binding (16.4%)" "IPR000212 (20%) IPR011604 (20%) IPR014016 (20%)" "DNA helicase, UvrD/REP type (20%) PD-(D/E)XK endonuclease-like domain superfamily (20%) UvrD-like helicase, ATP-binding domain (20%)" ALEPDCPYLQANAGDGSYLLSSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.8%) "GO:0004222 (33.8%) GO:0046872 (32.5%)" proteolysis (33.8%) "metalloendopeptidase activity (33.8%) metal ion binding (32.5%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" DPWGLRPAFYYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0016757 (56.7%) GO:0016740 (33.3%) GO:0004044 (10%)" "glycosyltransferase activity (56.7%) transferase activity (33.3%) amidophosphoribosyltransferase activity (10%)" "IPR000836 (25.2%) IPR017932 (25.2%) IPR029055 (24.8%)" "Phosphoribosyltransferase domain (25.2%) Glutamine amidotransferase type 2 domain (25.2%) Nucleophile aminohydrolases, N-terminal (24.8%)" GNVSADDAKNNFYWQDYLGDLDYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (27.8%) GO:0000272 (22.2%)" "GO:0004553 (44.4%) GO:0031176 (5.6%)" "xylan catabolic process (27.8%) polysaccharide catabolic process (22.2%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (44.4%) endo-1,4-beta-xylanase activity (5.6%)" "IPR001000 (32.1%) IPR017853 (28.6%) IPR044846 (25%)" "Glycoside hydrolase family 10 domain (32.1%) Glycoside hydrolase superfamily (28.6%) Glycoside hydrolase family 10 (25%)" AVYYEGLMALYELDPQQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.3%) "GO:0016787 (48.3%) GO:0102211 (3.4%)" carbohydrate metabolic process (48.3%) "hydrolase activity (48.3%) unsaturated rhamnogalacturonyl hydrolase activity (3.4%)" "IPR010905 (25.9%) IPR052043 (25.9%) IPR008928 (24.1%)" "Glycosyl hydrolase, family 88 (25.9%) Polysaccharide Degradation Enzymes (25.9%) Six-hairpin glycosidase superfamily (24.1%)" EGDTVLYGK Pseudomonadati Bacteria Pseudomonadati GO:0005737 (16.7%) "GO:0005524 (16.7%) GO:0044183 (16.7%) GO:0046872 (16.7%)" cytoplasm (16.7%) "ATP binding (16.7%) protein folding chaperone (16.7%) metal ion binding (16.7%)" "IPR011032 (27.6%) IPR020818 (27.6%) IPR037124 (27.6%)" "GroES-like superfamily (27.6%) GroES chaperonin family (27.6%) GroES chaperonin superfamily (27.6%)" SLMQGSGYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (36%) GO:0009279 (64%) iron ion transport (36%) cell outer membrane (64%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YHSWVVDR root "2.6.1.85 (44.4%) 4.1.3.27 (44.4%) 4.1.1.11 (11.1%)" "aminodeoxychorismate synthase (44.4%) anthranilate synthase (44.4%) aspartate 1-decarboxylase (11.1%)" "GO:0000162 (30.6%) GO:0008153 (0.8%) GO:0009396 (0.8%)" "GO:0005829 (29%) GO:0005737 (0.8%)" "GO:0004049 (29%) GO:0016740 (2.4%) GO:0008483 (1.6%)" "L-tryptophan biosynthetic process (30.6%) 4-aminobenzoate biosynthetic process (0.8%) folic acid-containing compound biosynthetic process (0.8%)" "cytosol (29%) cytoplasm (0.8%)" "anthranilate synthase activity (29%) transferase activity (2.4%) transaminase activity (1.6%)" "IPR006221 (24.1%) IPR017926 (24.1%) IPR029062 (24.1%)" "Anthranilate synthase/para-aminobenzoate synthase like domain (24.1%) Glutamine amidotransferase (24.1%) Class I glutamine amidotransferase-like (24.1%)" GVTMHTMNGDKHYTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" FTYGLTLNAEYK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.4%) IPR036942 (14.4%) IPR008969 (13.9%)" "TonB-dependent outer membrane protein, SusC/RagA (14.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.4%) Carboxypeptidase-like, regulatory domain superfamily (13.9%)" HHTVQGGSNLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.37 (57.1%) 1.1.1.40 (42.9%)" "malate dehydrogenase (57.1%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (42.9%)" GO:0006108 (34.7%) GO:0016020 (0.8%) "GO:0016615 (29.8%) GO:0016616 (29.8%) GO:0004473 (2.5%)" malate metabolic process (34.7%) membrane (0.8%) "malate dehydrogenase activity (29.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (29.8%) malate dehydrogenase (decarboxylating) (NADP+) activity (2.5%)" "IPR001236 (16.7%) IPR001557 (16.7%) IPR010945 (16.7%)" "Lactate/malate dehydrogenase, N-terminal (16.7%) L-lactate/malate dehydrogenase (16.7%) Malate dehydrogenase, type 2 (16.7%)" DNMATNPADLVQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.6%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.6%)" "IPR000185 (8.1%) IPR011115 (8.1%) IPR014001 (8.1%)" "Protein translocase subunit SecA (8.1%) SecA DEAD-like, N-terminal (8.1%) Helicase superfamily 1/2, ATP-binding domain (8.1%)" YSDPTLDTFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (48.3%) "GO:0016787 (48.3%) GO:0102211 (3.4%)" carbohydrate metabolic process (48.3%) "hydrolase activity (48.3%) unsaturated rhamnogalacturonyl hydrolase activity (3.4%)" "IPR010905 (25.9%) IPR052043 (25.9%) IPR008928 (24.1%)" "Glycosyl hydrolase, family 88 (25.9%) Polysaccharide Degradation Enzymes (25.9%) Six-hairpin glycosidase superfamily (24.1%)" ELEFGFGEEDLDGTLLPMATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (14.1%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (14.1%)" "IPR002489 (12.8%) IPR002932 (12.8%) IPR006982 (12.8%)" "Glutamate synthase, alpha subunit, C-terminal (12.8%) Glutamate synthase domain (12.8%) Glutamate synthase, central-N (12.8%)" LYLPLLLNYYMDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0004180 (100%) carboxypeptidase activity (100%) IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) LDAASYVNELMDDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (18.5%) GO:0005886 (18.5%) "GO:0003723 (22.2%) GO:0016787 (22.2%) GO:0004521 (18.5%)" mRNA catabolic process (18.5%) plasma membrane (18.5%) "RNA binding (22.2%) hydrolase activity (22.2%) RNA endonuclease activity (18.5%)" "IPR003607 (13%) IPR004087 (13%) IPR004088 (13%)" "HD/PDEase domain (13%) K Homology domain (13%) K Homology domain, type 1 (13%)" EQAFSQLLGWNYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR012910 (20.4%) IPR039426 (20.4%) IPR000531 (19.7%)" "TonB-dependent receptor, plug domain (20.4%) TonB-dependent receptor-like (20.4%) TonB-dependent receptor-like, beta-barrel (19.7%)" FNDLGEAQSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0016747 (58.6%) GO:0016787 (41.4%)" "acyltransferase activity, transferring groups other than amino-acyl groups (58.6%) hydrolase activity (41.4%)" "IPR003010 (21.2%) IPR000182 (20%) IPR001110 (20%)" "Carbon-nitrogen hydrolase (21.2%) GNAT domain (20%) Uncharacterised protein family UPF0012, conserved site (20%)" VSSESAQTSYDLLSEQFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" FENLWDVTNYALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030170 (50%) GO:0008483 (45%) GO:0016740 (5%)" "pyridoxal phosphate binding (50%) transaminase activity (45%) transferase activity (5%)" "IPR001917 (17.1%) IPR004839 (17.1%) IPR050087 (17.1%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (17.1%) Aminotransferase, class I/classII, large domain (17.1%) 8-amino-7-oxononanoate synthase class-II (17.1%)" LKNLEDDLALSLAALGLR root "GO:0051301 (19.9%) GO:0007059 (19.7%)" "GO:0005886 (19.8%) GO:0016020 (0.3%)" "GO:0003677 (20.1%) GO:0005524 (20.1%)" "cell division (19.9%) chromosome segregation (19.7%)" "plasma membrane (19.8%) membrane (0.3%)" "DNA binding (20.1%) ATP binding (20.1%)" "IPR041027 (12.6%) IPR050206 (12.6%) IPR002543 (12.5%)" "FtsK alpha domain (12.6%) FtsK/SpoIIIE/SftA cell division and DNA translocation (12.6%) FtsK domain (12.5%)" LSNFNCGDEDLNDFLLNESQLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016746 (50%) GO:0016747 (50%)" "acyltransferase activity (50%) acyltransferase activity, transferring groups other than amino-acyl groups (50%)" "IPR000182 (50%) IPR016181 (50%)" "GNAT domain (50%) Acyl-CoA N-acyltransferase (50%)" LATVFNR root "1.1.1.34 (34.2%) 3.4.-.- (25.3%) 2.7.13.3 (10.1%)" "hydroxymethylglutaryl-CoA reductase (NADPH) (34.2%) Acting on peptide bonds (peptidases) (25.3%) histidine kinase (10.1%)" "GO:0006508 (20.2%) GO:0015936 (3.2%) GO:0008299 (3.1%)" "GO:0016020 (4.3%) GO:0005789 (3.2%) GO:0005778 (3.1%)" "GO:0008233 (19.2%) GO:0004420 (3.2%) GO:0046872 (1.8%)" "proteolysis (20.2%) coenzyme A metabolic process (3.2%) isoprenoid biosynthetic process (3.1%)" "membrane (4.3%) endoplasmic reticulum membrane (3.2%) peroxisomal membrane (3.1%)" "peptidase activity (19.2%) hydroxymethylglutaryl-CoA reductase (NADPH) activity (3.2%) metal ion binding (1.8%)" "IPR001539 (13.7%) IPR051454 (13.7%) IPR002202 (2.7%)" "Peptidase U32 (13.7%) RNA and ubiquinone modification enzymes (13.7%) Hydroxymethylglutaryl-CoA reductase, class I/II (2.7%)" LGASLMLPLDEYNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" RNELLSGYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0051082 (24.7%)" "ATP binding (24.7%) ATP hydrolysis activity (24.7%) unfolded protein binding (24.7%)" "IPR001404 (19.8%) IPR019805 (19.8%) IPR020568 (19.8%)" "Heat shock protein Hsp90 family (19.8%) Heat shock protein Hsp90, conserved site (19.8%) Ribosomal protein uS5 domain 2-type superfamily (19.8%)" RSPLQDEYLEK Bacteria Bacteria 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (28.7%) GO:0006065 (12.5%)" "GO:0051287 (29.4%) GO:0003979 (28.7%) GO:0016616 (0.7%)" "polysaccharide biosynthetic process (28.7%) UDP-glucuronate biosynthetic process (12.5%)" "NAD binding (29.4%) UDP-glucose 6-dehydrogenase activity (28.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (0.7%)" "IPR001732 (11.3%) IPR014026 (11.3%) IPR014027 (11.3%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.3%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.3%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (11.3%)" NLPMFLR root "2.4.-.- (39.1%) 2.6.1.52 (17.4%) 2.7.7.7 (17.4%)" "Glycosyltransferases (39.1%) phosphoserine transaminase (17.4%) DNA-directed DNA polymerase (17.4%)" "GO:0072659 (11.2%) GO:0006446 (6.6%) GO:0006564 (1.3%)" "GO:0016020 (11.9%) GO:0005886 (11.2%) GO:0005852 (6.6%)" "GO:0003743 (6.6%) GO:0043022 (6.6%) GO:0016757 (3%)" "protein localization to plasma membrane (11.2%) regulation of translational initiation (6.6%) L-serine biosynthetic process (1.3%)" "membrane (11.9%) plasma membrane (11.2%) eukaryotic translation initiation factor 3 complex (6.6%)" "translation initiation factor activity (6.6%) ribosome binding (6.6%) glycosyltransferase activity (3%)" "IPR016024 (12%) IPR051851 (7.7%) IPR049152 (7.4%)" "Armadillo-type fold (12%) EFR3 Homologs (7.7%) EFR3-like, armadillo repeat (7.4%)" HLFGLPLDVTVTGGDGSLYHHVTAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR022045 (18%) IPR006530 (14%) IPR022385 (14%)" "Insecticide toxin TcdB middle/N-terminal (18%) YD repeat (14%) Rhs repeat-associated core (14%)" LYDLAYFMTTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006813 (4.1%) GO:0005886 (45.2%) "GO:0015079 (45.2%) GO:0008324 (4.1%) GO:0016491 (1.4%)" potassium ion transport (4.1%) plasma membrane (45.2%) "potassium ion transmembrane transporter activity (45.2%) monoatomic cation transmembrane transporter activity (4.1%) oxidoreductase activity (1.4%)" "IPR003148 (17.4%) IPR006037 (17.4%) IPR050721 (17.4%)" "Regulator of K+ conductance, N-terminal lobe (17.4%) Regulator of K+ conductance, C-terminal (17.4%) Trk/Ktr/HKT Potassium Transport (17.4%)" YLAEASQQSTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FSYDGSSTYGSYSPTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ELNDEAGAGLSAGDEQNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" HFDHVLPGNAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR029058 (50%) IPR049492 (50%)" "Alpha/Beta hydrolase fold (50%) BD-FAE-like domain (50%)" EVQDYDKVLAYADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32%)" VLFPGQGQAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "4.3.2.10 (50.9%) 3.5.1.2 (49.1%)" "imidazole glycerol-phosphate synthase (50.9%) glutaminase (49.1%)" GO:0000105 (20%) GO:0005737 (20%) "GO:0000107 (20%) GO:0016829 (20%) GO:0016787 (14.3%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "imidazoleglycerol-phosphate synthase activity (20%) lyase activity (20%) hydrolase activity (14.3%)" "IPR010139 (33.7%) IPR017926 (33.7%) IPR029062 (32.5%)" "Imidazole glycerol phosphate synthase, subunit H (33.7%) Glutamine amidotransferase (33.7%) Class I glutamine amidotransferase-like (32.5%)" LNPGELTSNGYLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" MFLTGFK root "1.3.99.4 (33.3%) 2.5.1.157 (33.3%) 7.2.2.21 (33.3%)" "3-oxosteroid 1-dehydrogenase (33.3%) rRNA small subunit aminocarboxypropyltransferase (33.3%) Cd(2+)-exporting ATPase (33.3%)" "GO:0055085 (19.5%) GO:0015031 (5.7%) GO:0016192 (5.7%)" "GO:0005886 (20.3%) GO:0016020 (11.4%) GO:0005737 (7.3%)" "GO:0005524 (1.6%) GO:0043565 (1.6%) GO:0106388 (1.6%)" "transmembrane transport (19.5%) protein transport (5.7%) vesicle-mediated transport (5.7%)" "plasma membrane (20.3%) membrane (11.4%) cytoplasm (7.3%)" "ATP binding (1.6%) sequence-specific DNA binding (1.6%) rRNA small subunit aminocarboxypropyltransferase activity (1.6%)" "IPR025684 (23.5%) IPR026377 (23.5%) IPR000515 (9.9%)" "Gliding motility protein SprA N-terminal domain (23.5%) Cell surface SprA (23.5%) ABC transporter type 1, transmembrane domain MetI-like (9.9%)" ATMLHLVANAGDLSDTQCQSGLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (50%) IPR012640 (25%) IPR013783 (25%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%) Membrane lipoprotein, lipid attachment site (25%) Immunoglobulin-like fold (25%)" SLYDAFVK root 1.2.1.8 (100%) betaine-aldehyde dehydrogenase (100%) "GO:0032259 (11.1%) GO:0000372 (3.7%) GO:0046677 (3.7%)" "GO:0009279 (20.4%) GO:0005886 (3.7%) GO:1990904 (3.7%)" "GO:0003677 (13%) GO:0008170 (13%) GO:0005524 (3.7%)" "methylation (11.1%) Group I intron splicing (3.7%) response to antibiotic (3.7%)" "cell outer membrane (20.4%) plasma membrane (3.7%) ribonucleoprotein complex (3.7%)" "DNA binding (13%) N-methyltransferase activity (13%) ATP binding (3.7%)" "IPR012944 (10.6%) IPR033985 (10.6%) IPR011990 (9.6%)" "RagB/SusD domain (10.6%) SusD-like, N-terminal (10.6%) Tetratricopeptide-like helical domain superfamily (9.6%)" APDYDDWSTVAENGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.3%) GO:0006529 (1.7%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (23.3%) GO:0000166 (1.7%)" "L-asparagine biosynthetic process (23.3%) obsolete asparagine biosynthetic process (1.7%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (23.3%) nucleotide binding (1.7%)" "IPR004618 (34.1%) IPR006195 (34.1%) IPR045864 (31.8%)" "Aspartate--ammonia ligase (34.1%) Aminoacyl-tRNA synthetase, class II (34.1%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (31.8%)" SQLDNLFNETLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003677 (50%) GO:0003700 (50%)" "DNA binding (50%) DNA-binding transcription factor activity (50%)" "IPR000524 (20%) IPR008920 (20%) IPR011711 (20%)" "Transcription regulator HTH, GntR (20%) Transcription regulator FadR/GntR, C-terminal (20%) GntR, C-terminal (20%)" HQLETTGEAVALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006101 (8.3%) IPR006102 (8.3%) IPR006103 (8.3%)" "Glycoside hydrolase, family 2 (8.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8.3%) Glycoside hydrolase family 2, catalytic domain (8.3%)" LDVLNVTYLQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" LQLLQQHLAYYEQLKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016020 (49%) GO:0005783 (2%)" GO:0004467 (49%) "membrane (49%) endoplasmic reticulum (2%)" long-chain fatty acid-CoA ligase activity (49%) "IPR000873 (33.3%) IPR020845 (33.3%) IPR042099 (33.3%)" "AMP-dependent synthetase/ligase domain (33.3%) AMP-binding, conserved site (33.3%) ANL, N-terminal domain (33.3%)" GMSEAHYVLVGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (52.8%) IPR038377 (47.2%)" "Sodium/solute symporter (52.8%) Sodium/glucose symporter superfamily (47.2%)" YDDQFVTNYALLNVLPQLKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (24.1%) GO:0005886 (25.5%) "GO:0042910 (25.5%) GO:0015562 (24.8%)" response to toxic substance (24.1%) plasma membrane (25.5%) "xenobiotic transmembrane transporter activity (25.5%) efflux transmembrane transporter activity (24.8%)" "IPR001036 (34%) IPR004764 (33%) IPR027463 (33%)" "Acriflavin resistance protein (34%) Multidrug resistance protein MdtF-like (33%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33%)" VMDAETGHEMYLDTSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002035 (34.1%) IPR002881 (34.1%) IPR036465 (31.8%)" "von Willebrand factor, type A (34.1%) Domain of unknown function DUF58 (34.1%) von Willebrand factor A-like domain superfamily (31.8%)" AKVEAPLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001278 (13%) IPR001412 (13%) IPR005148 (13%)" "Arginine-tRNA ligase (13%) Aminoacyl-tRNA synthetase, class I, conserved site (13%) Arginyl tRNA synthetase N-terminal domain (13%)" LNETEDYLLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" VPVTLNYGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032293 (100%) Protein of unknown function DUF4840 (100%) LQSLLQVGAGAFDGALLAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FFSSDAAVFSGSYFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" VASLTWDQVKVLAEDK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000911 (14.3%) IPR006519 (14.3%) IPR020783 (14.3%)" "Ribosomal protein uL11 (14.3%) Large ribosomal subunit protein uL11, bacteria (14.3%) Large ribosomal subunit protein uL11, C-terminal (14.3%)" YSESVSYR root "GO:0003007 (0.9%) GO:0003183 (0.9%) GO:0007156 (0.9%)" "GO:0005737 (33%) GO:0016020 (26.1%) GO:0005886 (0.9%)" "GO:0016787 (33%) GO:0005509 (0.9%)" "heart morphogenesis (0.9%) mitral valve morphogenesis (0.9%) homophilic cell-cell adhesion (0.9%)" "cytoplasm (33%) membrane (26.1%) plasma membrane (0.9%)" "hydrolase activity (33%) calcium ion binding (0.9%)" "IPR004843 (19.8%) IPR032285 (19.8%) IPR032288 (19.8%)" "Calcineurin-like, phosphoesterase domain (19.8%) Calcineurin-like phosphoesterase, N-terminal (19.8%) Calcineurin-like phosphoesterase, C-terminal (19.8%)" LTDADMLEVVTMVYGGLVNK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.7.2.8 (100%) acetylglutamate kinase (100%) GO:0042450 (25%) GO:0005737 (25%) "GO:0003991 (25%) GO:0005524 (25%)" L-arginine biosynthetic process via ornithine (25%) cytoplasm (25%) "acetylglutamate kinase activity (25%) ATP binding (25%)" "IPR001048 (25%) IPR004662 (25%) IPR036393 (25%)" "Aspartate/glutamate/uridylate kinase (25%) Acetylglutamate kinase family (25%) Acetylglutamate kinase-like superfamily (25%)" LYEMASSLQGTELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.1%) GO:0016787 (48.9%) membrane (51.1%) hydrolase activity (48.9%) "IPR000560 (51.1%) IPR029033 (48.9%)" "Histidine phosphatase superfamily, clade-2 (51.1%) Histidine phosphatase superfamily (48.9%)" ANNPLYETTEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" MLNMPNFEWTQLGSTDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" AGLSQLLEASTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR021272 (100%) Protein of unknown function DUF2851 (100%) MPSAVGYQPTLASEMGAMQER Bacteria Bacteria "7.1.2.2 (98.7%) 3.6.3.14 (1.3%)" "H(+)-transporting two-sector ATPase (98.7%) Transferred entry: 7.1.2.2 (1.3%)" "GO:0045259 (23.6%) GO:0005886 (23.3%)" "GO:0005524 (23.6%) GO:0046933 (23.6%) GO:0016787 (6%)" "proton-transporting ATP synthase complex (23.6%) plasma membrane (23.3%)" "ATP binding (23.6%) proton-transporting ATP synthase activity, rotational mechanism (23.6%) hydrolase activity (6%)" "IPR000194 (10%) IPR005722 (10%) IPR050053 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, F1 complex, beta subunit (10%) ATPase alpha/beta chains (10%)" GDLDLDEDYWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.- (100%) Phosphoric monoester hydrolases (100%) GO:0005829 (33.3%) "GO:0008270 (33.3%) GO:0042578 (33.3%)" cytosol (33.3%) "zinc ion binding (33.3%) phosphoric ester hydrolase activity (33.3%)" "IPR003141 (25%) IPR004013 (25%) IPR016195 (25%)" "Polymerase/histidinol phosphatase, N-terminal (25%) PHP domain (25%) Polymerase/histidinol phosphatase-like (25%)" SLPLNRPAGGVTPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR013783 (20%) IPR028994 (20%) IPR034641 (20%)" "Immunoglobulin-like fold (20%) Integrin alpha, N-terminal (20%) Polysaccharide lyase family 11 (20%)" GDYLNLENLTLGYDLPLRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (15.1%) IPR039426 (15.1%) IPR012910 (14.4%)" "TonB-dependent receptor-like, beta-barrel (15.1%) TonB-dependent receptor-like (15.1%) TonB-dependent receptor, plug domain (14.4%)" NWLFDLGLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (50.9%) IPR027417 (49.1%)" "Tetraacyldisaccharide 4'-kinase (50.9%) P-loop containing nucleoside triphosphate hydrolase (49.1%)" SLSGYQTSSSATSFQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) MLNHEELSREETR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.18 (100%) anthranilate phosphoribosyltransferase (100%) GO:0000162 (25%) GO:0005829 (25%) "GO:0000287 (25%) GO:0004048 (25%)" L-tryptophan biosynthetic process (25%) cytosol (25%) "magnesium ion binding (25%) anthranilate phosphoribosyltransferase activity (25%)" "IPR000312 (20.6%) IPR005940 (20.6%) IPR017459 (20.6%)" "Glycosyl transferase, family 3 (20.6%) Anthranilate phosphoribosyl transferase (20.6%) Glycosyl transferase family 3, N-terminal domain (20.6%)" FVQNLTEMLSQSGRV Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" NHNLEAVVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (14.6%) IPR004602 (14.6%) IPR017871 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) UvrABC system subunit A (14.6%) ABC transporter-like, conserved site (14.6%)" TLGFAPQK root "GO:0010499 (13.8%) GO:0006281 (11.3%) GO:0005975 (2.5%)" "GO:0005829 (13.8%) GO:1990111 (13.8%) GO:0016607 (11.3%)" "GO:0016504 (13.8%) GO:0070628 (13.8%) GO:0004553 (2.5%)" "proteasomal ubiquitin-independent protein catabolic process (13.8%) DNA repair (11.3%) carbohydrate metabolic process (2.5%)" "cytosol (13.8%) spermatoproteasome complex (13.8%) nuclear speck (11.3%)" "peptidase activator activity (13.8%) proteasome binding (13.8%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.5%)" "IPR007139 (62.8%) IPR032430 (5.7%) IPR035309 (5.7%)" "Protein of unknown function DUF349 (62.8%) Proteasome activator Blm10, middle HEAT repeats region (5.7%) Proteasome activator complex subunit 4 (5.7%)" LHGWVSQQMFANLWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" EFAGYHSQLAAAADPTEVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.7%) IPR046357 (25.3%) IPR000297 (24%)" "Periplasmic chaperone PpiD (26.7%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.3%) Peptidyl-prolyl cis-trans isomerase, PpiC-type (24%)" SHGEELQALSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (33.3%) GO:0005886 (33.3%) GO:0020037 (33.3%) cytochrome complex assembly (33.3%) plasma membrane (33.3%) heme binding (33.3%) "IPR002541 (33.3%) IPR007816 (33.3%) IPR045062 (33.3%)" "Cytochrome c assembly protein (33.3%) ResB-like domain (33.3%) Cytochrome c-type biogenesis protein CcsA/CcmC (33.3%)" VALTMALPLGANLGGMGTPLGTPPNAFAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0005315 (50%) plasma membrane (50%) phosphate transmembrane transporter activity (50%) "IPR001898 (50%) IPR004680 (50%)" "Solute carrier family 13 (50%) Citrate transporter-like domain (50%)" VKQLSLADMFAETLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.2%) GO:0006164 (11.2%) GO:0009156 (10.7%)" "GO:0002189 (11.2%) GO:0005737 (11.2%)" "GO:0000287 (11.2%) GO:0004749 (11.2%) GO:0016301 (11.2%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.2%) purine nucleotide biosynthetic process (11.2%) ribonucleoside monophosphate biosynthetic process (10.7%)" "ribose phosphate diphosphokinase complex (11.2%) cytoplasm (11.2%)" "magnesium ion binding (11.2%) ribose phosphate diphosphokinase activity (11.2%) kinase activity (11.2%)" "IPR000836 (18.8%) IPR005946 (18.8%) IPR029057 (18.8%)" "Phosphoribosyltransferase domain (18.8%) Ribose-phosphate pyrophosphokinase (18.8%) Phosphoribosyltransferase-like (18.8%)" NGNNMYTWENWNNAVNYWQASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) YAGHLVLNDTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) "GO:0005886 (16.4%) GO:0016020 (0.4%)" "GO:0005524 (16.8%) GO:0015086 (16.8%) GO:0016887 (16.8%)" "plasma membrane (16.4%) membrane (0.4%)" "ATP binding (16.8%) cadmium ion transmembrane transporter activity (16.8%) ATP hydrolysis activity (16.8%)" "IPR001757 (10.4%) IPR051014 (10.4%) IPR018303 (10.2%)" "P-type ATPase (10.4%) Cation Transport ATPase Type IB (10.4%) P-type ATPase, phosphorylation site (10.2%)" VHETTLEVNLNAVVANLNYYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.8%) "GO:0005524 (20.3%) GO:0016881 (20.3%) GO:0008784 (19.8%)" D-alanine biosynthetic process (19.8%) "ATP binding (20.3%) acid-amino acid ligase activity (20.3%) alanine racemase activity (19.8%)" "IPR001608 (10.3%) IPR013221 (10.3%) IPR051046 (10.3%)" "Alanine racemase, N-terminal (10.3%) Mur ligase, central (10.3%) MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.3%)" ELNTYLDQLKDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0042910 (50%) plasma membrane (50%) xenobiotic transmembrane transporter activity (50%) "IPR001036 (53.8%) IPR027463 (46.2%)" "Acriflavin resistance protein (53.8%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (46.2%)" LKDLYLK root "2.7.7.7 (8%) 2.7.13.3 (7%) 6.3.5.4 (6.6%)" "DNA-directed DNA polymerase (8%) histidine kinase (7%) asparagine synthase (glutamine-hydrolyzing) (6.6%)" "GO:0007165 (1.7%) GO:0007018 (1.6%) GO:0010468 (1.6%)" "GO:0016020 (4.8%) GO:0005737 (2.6%) GO:0005886 (1.9%)" "GO:0005524 (5.5%) GO:0046872 (1.9%) GO:0003682 (1.6%)" "signal transduction (1.7%) microtubule-based movement (1.6%) regulation of gene expression (1.6%)" "membrane (4.8%) cytoplasm (2.6%) plasma membrane (1.9%)" "ATP binding (5.5%) metal ion binding (1.9%) chromatin binding (1.6%)" "IPR027417 (4.4%) IPR016024 (1.3%) IPR044986 (1.2%)" "P-loop containing nucleoside triphosphate hydrolase (4.4%) Armadillo-type fold (1.3%) Kinesin-like protein KIF15/KIN-12 (1.2%)" SLGEALTLR root 5.1.1.1 (100%) alanine racemase (100%) GO:0070508 (4.5%) "GO:0009279 (68.2%) GO:0016020 (4.5%)" "GO:0005524 (4.5%) GO:0015485 (4.5%) GO:0016887 (4.5%)" cholesterol import (4.5%) "cell outer membrane (68.2%) membrane (4.5%)" "ATP binding (4.5%) cholesterol binding (4.5%) ATP hydrolysis activity (4.5%)" "IPR011990 (25.4%) IPR012944 (25.4%) IPR033985 (25.4%)" "Tetratricopeptide-like helical domain superfamily (25.4%) RagB/SusD domain (25.4%) SusD-like, N-terminal (25.4%)" NLVEQVESRPYDVLNSEEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) QSDWFPVFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SDLLSEEELHYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0042274 (14.8%) GO:0042254 (1.6%)" GO:0005737 (16.4%) "GO:0003924 (16.4%) GO:0005525 (16.4%) GO:0019843 (16.4%)" "ribosomal small subunit biogenesis (14.8%) ribosome biogenesis (1.6%)" cytoplasm (16.4%) "GTPase activity (16.4%) GTP binding (16.4%) rRNA binding (16.4%)" "IPR004881 (16.7%) IPR010914 (16.7%) IPR012340 (16.7%)" "Ribosome biogenesis GTPase RsgA (16.7%) RsgA GTPase domain (16.7%) Nucleic acid-binding, OB-fold (16.7%)" NPAMLLSDGVLGQMMEK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "1.2.7.7 (76.3%) 1.2.7.1 (13.2%) 1.2.7.3 (5.3%)" "3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (76.3%) pyruvate synthase (13.2%) 2-oxoglutarate synthase (5.3%)" "GO:0016491 (76.2%) GO:0043807 (19.2%) GO:0019164 (3.1%)" "oxidoreductase activity (76.2%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity (19.2%) pyruvate synthase activity (3.1%)" "IPR002880 (20.1%) IPR052368 (20.1%) IPR029061 (20%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (20.1%) 2-oxoacid oxidoreductase subunit (20.1%) Thiamin diphosphate-binding fold (20%)" PSTGLTPVDYFGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016747 (49.2%) GO:0016788 (47.5%) GO:0016787 (3.3%)" "acyltransferase activity, transferring groups other than amino-acyl groups (49.2%) hydrolase activity, acting on ester bonds (47.5%) hydrolase activity (3.3%)" "IPR005181 (17.5%) IPR000801 (16.9%) IPR050583 (16.9%)" "Sialate O-acetylesterase domain (17.5%) Esterase-like (16.9%) Mycobacterial A85 antigen (16.9%)" NMVPFDSR root 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (15.5%) GO:0035999 (15.1%) GO:0032259 (11%)" "GO:0005829 (15.5%) GO:0005737 (0%) GO:0016020 (0%)" "GO:0004372 (15.5%) GO:0030170 (15.5%) GO:0008168 (11%)" "glycine biosynthetic process from serine (15.5%) tetrahydrofolate interconversion (15.1%) methylation (11%)" "cytosol (15.5%) cytoplasm (0%) membrane (0%)" "glycine hydroxymethyltransferase activity (15.5%) pyridoxal phosphate binding (15.5%) methyltransferase activity (11%)" "IPR039429 (14.4%) IPR049943 (14.4%) IPR015422 (14.3%)" "Serine hydroxymethyltransferase-like domain (14.4%) Serine hydroxymethyltransferase-like (14.4%) Pyridoxal phosphate-dependent transferase, small domain (14.3%)" QAGLVDPAKVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.2%) GO:0005737 (16.1%) "GO:0005524 (17.2%) GO:0140662 (17.2%) GO:0016853 (16.1%)" protein refolding (17.2%) cytoplasm (16.1%) "ATP binding (17.2%) ATP-dependent protein folding chaperone (17.2%) isomerase activity (16.1%)" "IPR001844 (17%) IPR002423 (17%) IPR018370 (17%)" "Chaperonin Cpn60/GroEL (17%) Chaperonin Cpn60/GroEL/TCP-1 family (17%) Chaperonin Cpn60, conserved site (17%)" ELASNPANDFVTLDGDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.7%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.7%)" "IPR000185 (7.9%) IPR011115 (7.9%) IPR011130 (7.9%)" "Protein translocase subunit SecA (7.9%) SecA DEAD-like, N-terminal (7.9%) SecA, preprotein cross-linking domain (7.9%)" VNVMKEDPLFLLNVAVSDNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella TNFAFLR root "3.1.22.- (50%) 6.1.1.20 (50%)" "Endodeoxyribonucleases producing other than 5'-phosphomonoesters (50%) phenylalanine--tRNA ligase (50%)" "GO:0009313 (10.6%) GO:0043039 (10.6%) GO:0006886 (4.5%)" "GO:0005829 (4.7%) GO:0000139 (4.5%) GO:0034066 (4.5%)" "GO:0005524 (11.1%) GO:0004556 (10.6%) GO:0004812 (10.6%)" "oligosaccharide catabolic process (10.6%) tRNA aminoacylation (10.6%) intracellular protein transport (4.5%)" "cytosol (4.7%) Golgi membrane (4.5%) Ric1-Rgp1 guanyl-nucleotide exchange factor complex (4.5%)" "ATP binding (11.1%) alpha-amylase activity (10.6%) aminoacyl-tRNA ligase activity (10.6%)" "IPR006047 (13.2%) IPR012947 (13.2%) IPR017853 (12.6%)" "Glycosyl hydrolase family 13, catalytic domain (13.2%) Threonyl/alanyl tRNA synthetase, SAD (13.2%) Glycoside hydrolase superfamily (12.6%)" PGLLYAPQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (47.1%) GO:0015159 (52.9%) membrane (47.1%) polysaccharide transmembrane transporter activity (52.9%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" FGWLDFLDDREVSK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.3.1.- (100%) Transferring groups other than amino-acyl groups (100%) "GO:0016740 (66.7%) GO:0016787 (25%) GO:0016747 (8.3%)" "transferase activity (66.7%) hydrolase activity (25%) acyltransferase activity, transferring groups other than amino-acyl groups (8.3%)" "IPR039968 (50%) IPR016181 (48.5%) IPR000182 (1.5%)" "Bacterial ceramide synthase-like (50%) Acyl-CoA N-acyltransferase (48.5%) GNAT domain (1.5%)" YSNYGFGDFGSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.6.- (100%) Sulfuric ester hydrolases (100%) "GO:0005886 (36.8%) GO:0016020 (3.4%)" "GO:0046872 (34.5%) GO:0016787 (23%) GO:0016740 (2.3%)" "plasma membrane (36.8%) membrane (3.4%)" "metal ion binding (34.5%) hydrolase activity (23%) transferase activity (2.3%)" "IPR000917 (25.8%) IPR050448 (25.8%) IPR012160 (24.2%)" "Sulfatase, N-terminal (25.8%) OpgB/LTA synthase bacterial cell wall biosynthesis (25.8%) Lipoteichoic acid synthase-like (24.2%)" NEDGSLLFR Pseudomonadati Bacteria Pseudomonadati GO:0015891 (17.6%) "GO:0009279 (17.6%) GO:0005737 (5.9%)" "GO:0015344 (17.6%) GO:0016301 (17.6%) GO:0038023 (17.6%)" siderophore transport (17.6%) "cell outer membrane (17.6%) cytoplasm (5.9%)" "siderophore uptake transmembrane transporter activity (17.6%) kinase activity (17.6%) signaling receptor activity (17.6%)" "IPR025393 (44%) IPR029044 (43%) IPR000531 (1.5%)" "Domain of unknown function DUF4301 (44%) Nucleotide-diphospho-sugar transferases (43%) TonB-dependent receptor-like, beta-barrel (1.5%)" AAFLLAGAEVTVGDKYPAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (34.2%) IPR002933 (34.2%) IPR011650 (31.6%)" "Peptidase M20C, Xaa-His dipeptidase (34.2%) Peptidase M20 (34.2%) Peptidase M20, dimerisation domain (31.6%)" YEGNPLLTSTVPDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" TALPTHNHPEGLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0046872 (77.3%) GO:0016787 (22.7%)" "metal ion binding (77.3%) hydrolase activity (22.7%)" "IPR005502 (34%) IPR050792 (34%) IPR036705 (32%)" "ADP-ribosylation/Crystallin J1 (34%) ADP-ribosylglycohydrolase (34%) ADP-ribosylation/Crystallin J1 superfamily (32%)" LNDNNLTSLDDLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.107 (100%) peptidase Do (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001478 (17.6%) IPR001940 (17.6%) IPR009003 (17.6%)" "PDZ domain (17.6%) Peptidase S1C (17.6%) Peptidase S1, PA clan (17.6%)" QEDPTWLVDQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.7%) IPR000795 (7.7%) IPR005225 (7.7%)" "Elongation factor EFG, domain V-like (7.7%) Translational (tr)-type GTP-binding domain (7.7%) Small GTP-binding domain (7.7%)" LKELSLAYDFPHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" LDAETLNMVAEEFGFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (25%) "GO:0003743 (25%) GO:0003924 (25%) GO:0005525 (25%)" cytoplasm (25%) "translation initiation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (8.6%) IPR005225 (8.6%) IPR006847 (8.6%)" "Translational (tr)-type GTP-binding domain (8.6%) Small GTP-binding domain (8.6%) Translation initiation factor IF-2, N-terminal (8.6%)" VPYTQSLQYFTALQTLNLPSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) "GO:0004252 (47.1%) GO:0008236 (2.9%)" proteolysis (50%) "serine-type endopeptidase activity (47.1%) serine-type peptidase activity (2.9%)" "IPR001375 (21%) IPR029058 (20.4%) IPR002469 (19.8%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (21%) Alpha/Beta hydrolase fold (20.4%) Dipeptidylpeptidase IV, N-terminal domain (19.8%)" LTAELVSLK root "GO:0006412 (6.3%) GO:0007018 (6.3%) GO:0008033 (6.3%)" "GO:0005737 (6.3%) GO:0005840 (6.3%) GO:0015630 (6.3%)" "GO:0003735 (6.3%) GO:0003777 (6.3%) GO:0005524 (6.3%)" "translation (6.3%) microtubule-based movement (6.3%) tRNA processing (6.3%)" "cytoplasm (6.3%) ribosome (6.3%) microtubule cytoskeleton (6.3%)" "structural constituent of ribosome (6.3%) microtubule motor activity (6.3%) ATP binding (6.3%)" "IPR001752 (8.3%) IPR004038 (8.3%) IPR011990 (8.3%)" "Kinesin motor domain (8.3%) Ribosomal protein eL8/eL30/eS12/Gadd45 (8.3%) Tetratricopeptide-like helical domain superfamily (8.3%)" YGDGVEDKNLHTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR000565 (7.7%) IPR001241 (7.7%) IPR002288 (7.7%)" "DNA topoisomerase, type IIA, subunit B (7.7%) DNA topoisomerase, type IIA (7.7%) DNA gyrase B subunit, C-terminal (7.7%)" QYQVNMGMEDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" VADGEMFTDTDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (49.2%) "GO:0022857 (49.2%) GO:0005524 (1.6%)" plasma membrane (49.2%) "transmembrane transporter activity (49.2%) ATP binding (1.6%)" "IPR025857 (34.4%) IPR050250 (33.3%) IPR003838 (32.2%)" "MacB-like periplasmic core domain (34.4%) Macrolide Exporter MacB (33.3%) ABC3 transporter permease, C-terminal (32.2%)" YVCDGGTFADDDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.3%) IPR023996 (15.3%) IPR023997 (15.3%)" "TonB-dependent receptor, plug domain (15.3%) TonB-dependent outer membrane protein, SusC/RagA (15.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.3%)" EAQEASTLSSVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR016047 (51%) IPR011055 (49%)" "M23ase, beta-sheet core domain (51%) Duplicated hybrid motif (49%)" APGTLGQDVDVVSGQVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" GLNLLNGDMDELKAHGETQLDGVSAFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.5%) IPR018165 (9.5%) IPR050058 (9.5%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.5%) Alanyl-tRNA synthetase, class IIc, core domain (9.5%) Alanine--tRNA ligase (9.5%)" LDSFPYADQVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (34.2%) IPR051612 (34.2%) IPR043148 (31.6%)" "CDP-glycerol glycerophosphotransferase (34.2%) Teichoic Acid Biosynthesis Enzymes (34.2%) CDP-glycerol glycerophosphotransferase, C-terminal domain (31.6%)" KLLDLGDFLGVK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004824 (16.7%) GO:0005524 (16.5%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) lysine-tRNA ligase activity (16.7%) ATP binding (16.5%)" "IPR004365 (12.4%) IPR044136 (12.4%) IPR002313 (12.3%)" "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.4%) Lysine-tRNA ligase, class II, N-terminal (12.4%) Lysine-tRNA ligase, class II (12.3%)" GSGCLCLNGAAAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.11 (100%) aspartate 1-decarboxylase (100%) "GO:0006523 (25%) GO:0015940 (25%)" GO:0005829 (25%) GO:0004068 (25%) "alanine biosynthetic process (25%) pantothenate biosynthetic process (25%)" cytosol (25%) aspartate 1-decarboxylase activity (25%) "IPR003190 (50%) IPR009010 (50%)" "Aspartate decarboxylase (50%) Aspartate decarboxylase-like domain superfamily (50%)" SGDHVGLWAHENSSWAGPGNPETLLSMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (34.8%) IPR011990 (30.4%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (30.4%)" LEDEVLER root "6.1.1.10 (75.8%) 2.7.9.3 (18.2%) 3.2.1.143 (3%)" "methionine--tRNA ligase (75.8%) selenide, water dikinase (18.2%) poly(ADP-ribose) glycohydrolase (3%)" "GO:0006431 (9.5%) GO:0016260 (2.8%) GO:0006355 (1.2%)" "GO:0005829 (9.5%) GO:0005737 (5.1%) GO:0005634 (2%)" "GO:0005524 (13%) GO:0004825 (9.5%) GO:0046872 (9.5%)" "methionyl-tRNA aminoacylation (9.5%) selenocysteine biosynthetic process (2.8%) regulation of DNA-templated transcription (1.2%)" "cytosol (9.5%) cytoplasm (5.1%) nucleus (2%)" "ATP binding (13%) methionine-tRNA ligase activity (9.5%) metal ion binding (9.5%)" "IPR009080 (5.5%) IPR012340 (5.5%) IPR014729 (5.5%)" "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (5.5%) Nucleic acid-binding, OB-fold (5.5%) Rossmann-like alpha/beta/alpha sandwich fold (5.5%)" LVLYPAAQNEQNAMLSLFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) SFTNLYAMYNTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" DAQHLLYAYDNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23.5%) "GO:0000155 (23.5%) GO:0003700 (23.5%) GO:0043565 (23.5%)" membrane (23.5%) "phosphorelay sensor kinase activity (23.5%) DNA-binding transcription factor activity (23.5%) sequence-specific DNA binding (23.5%)" "IPR011110 (6.6%) IPR001789 (6.4%) IPR003594 (6.4%)" "Two component regulator propeller (6.6%) Signal transduction response regulator, receiver domain (6.4%) Histidine kinase/HSP90-like ATPase domain (6.4%)" LDQLEDKFNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (57.1%) IPR012547 (35.7%) IPR027417 (7.1%)" "AAA-ATPase-like domain (57.1%) PD-(D/E)XK nuclease superfamily 9 (35.7%) P-loop containing nucleoside triphosphate hydrolase (7.1%)" TLGLMGLGNLGMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.2%) GO:0033711 (2.8%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.2%) 4-phosphoerythronate dehydrogenase activity (2.8%)" "IPR006139 (19.8%) IPR006140 (19.8%) IPR029753 (19.8%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (19.8%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (19.8%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site (19.8%)" NSYLPTVMDFAFFDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.8%) IPR015171 (14.8%) IPR019492 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Cyclomaltodextrinase, N-terminal (14.8%) Cyclo-malto-dextrinase, C-terminal (14.8%)" GSSFYGGTADLALLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.9%) GO:0004560 (51.1%) carbohydrate metabolic process (48.9%) alpha-L-fucosidase activity (51.1%) "IPR049053 (17.3%) IPR054363 (17.3%) IPR008928 (16.5%)" "Alpha fucosidase A-like, C-terminal domain (17.3%) Glycosyl hydrolase family 95, catalytic domain (17.3%) Six-hairpin glycosidase superfamily (16.5%)" GGNLLFVTPTQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR008979 (25%) IPR013830 (25%) IPR036514 (25%)" "Galactose-binding-like domain superfamily (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" LARDEFPDEDVTVR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006139 (20%) GO:0006412 (20%)" GO:0005737 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "nucleobase-containing compound metabolic process (20%) translation (20%)" cytoplasm (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR003029 (7.2%) IPR006641 (7.2%) IPR018974 (7.2%)" "S1 domain (7.2%) YqgF/RNase H-like domain (7.2%) Tex-like protein, N-terminal (7.2%)" GYGVYDANTLDLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (66.7%) IPR011047 (27.8%) IPR011044 (5.6%)" "WD40/YVTN repeat-like-containing domain superfamily (66.7%) Quinoprotein alcohol dehydrogenase-like superfamily (27.8%) Quinoprotein amine dehydrogenase, beta chain-like (5.6%)" LADVAPSLLHLMGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" MVLDFEK root "3.4.19.12 (53.3%) 2.7.7.80 (10%) 2.7.11.1 (6.7%)" "ubiquitinyl hydrolase 1 (53.3%) molybdopterin-synthase adenylyltransferase (10%) non-specific serine/threonine protein kinase (6.7%)" "GO:0016579 (6.2%) GO:0043161 (5.5%) GO:0061136 (5.5%)" "GO:0005886 (3.4%) GO:0016020 (3.1%) GO:0005634 (2.4%)" "GO:0005524 (9.9%) GO:0004843 (6.2%) GO:0070628 (5.5%)" "protein deubiquitination (6.2%) proteasome-mediated ubiquitin-dependent protein catabolic process (5.5%) regulation of proteasomal protein catabolic process (5.5%)" "plasma membrane (3.4%) membrane (3.1%) nucleus (2.4%)" "ATP binding (9.9%) cysteine-type deubiquitinase activity (6.2%) proteasome binding (5.5%)" "IPR011051 (4%) IPR013096 (4%) IPR014710 (4%)" "RmlC-like cupin domain superfamily (4%) Cupin 2, conserved barrel (4%) RmlC-like jelly roll fold (4%)" GTNTLNETNFLADYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" WYRPDNQALLLVGDVDVNHLEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.7%) "GO:0004222 (33.7%) GO:0046872 (32.7%)" proteolysis (33.7%) "metalloendopeptidase activity (33.7%) metal ion binding (32.7%)" "IPR001431 (20.1%) IPR007863 (20.1%) IPR011765 (20.1%)" "Peptidase M16, zinc-binding site (20.1%) Peptidase M16, C-terminal (20.1%) Peptidase M16, N-terminal (20.1%)" SLALHPASTLFGAFSESMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019346 (20%) GO:0005737 (20%) "GO:0016846 (20%) GO:0030170 (20%) GO:0016740 (14.3%)" transsulfuration (20%) cytoplasm (20%) "carbon-sulfur lyase activity (20%) pyridoxal phosphate binding (20%) transferase activity (14.3%)" "IPR000277 (25%) IPR015421 (25%) IPR015422 (25%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (25%) Pyridoxal phosphate-dependent transferase, major domain (25%) Pyridoxal phosphate-dependent transferase, small domain (25%)" SWTFDPK root "1.7.3.3 (33.3%) 2.3.1.85 (33.3%) 3.1.2.14 (33.3%)" "factor independent urate hydroxylase (33.3%) fatty-acid synthase system (33.3%) oleoyl-[acyl-carrier-protein] hydrolase (33.3%)" "GO:0006082 (3%) GO:0006145 (3%) GO:0006633 (3%)" "GO:0009279 (12.1%) GO:0005777 (3%) GO:0005789 (3%)" "GO:0005509 (18.2%) GO:0004312 (3%) GO:0004314 (3%)" "organic acid metabolic process (3%) purine nucleobase catabolic process (3%) fatty acid biosynthetic process (3%)" "cell outer membrane (12.1%) peroxisome (3%) endoplasmic reticulum membrane (3%)" "calcium ion binding (18.2%) fatty acid synthase activity (3%) [acyl-carrier-protein] S-malonyltransferase activity (3%)" "IPR001343 (6.1%) IPR002035 (6.1%) IPR011049 (6.1%)" "RTX calcium-binding nonapeptide repeat (6.1%) von Willebrand factor, type A (6.1%) Serralysin-like metalloprotease, C-terminal (6.1%)" STGQNVELYVGGTNAGTGPDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TLYALVVDPHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" GSFDYYYEHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.1%) IPR008969 (11.1%) IPR012910 (11.1%)" "TonB-dependent receptor-like, beta-barrel (11.1%) Carboxypeptidase-like, regulatory domain superfamily (11.1%) TonB-dependent receptor, plug domain (11.1%)" ASTVNVMVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR019554 (33.7%) IPR049712 (33.7%) IPR003715 (32.7%)" "Soluble ligand binding domain (33.7%) Polysaccharide export protein (33.7%) Polysaccharide export protein, N-terminal domain (32.7%)" RVLFCDDSLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (20.1%) GO:0006189 (13.1%) GO:0006164 (7%)" "GO:0004044 (20.1%) GO:0046872 (19.6%) GO:0051536 (19.6%)" "purine nucleobase biosynthetic process (20.1%) 'de novo' IMP biosynthetic process (13.1%) purine nucleotide biosynthetic process (7%)" "amidophosphoribosyltransferase activity (20.1%) metal ion binding (19.6%) iron-sulfur cluster binding (19.6%)" "IPR000836 (20.7%) IPR017932 (20.2%) IPR029057 (20.2%)" "Phosphoribosyltransferase domain (20.7%) Glutamine amidotransferase type 2 domain (20.2%) Phosphoribosyltransferase-like (20.2%)" SGASESNTLVVGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.4.2.10 (100%) phosphoglucosamine mutase (100%) "GO:0005975 (14.3%) GO:0006048 (14.3%) GO:0009252 (14.3%)" GO:0005829 (14.3%) "GO:0000287 (14.3%) GO:0004615 (14.3%) GO:0008966 (14.3%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.3%) peptidoglycan biosynthetic process (14.3%)" cytosol (14.3%) "magnesium ion binding (14.3%) phosphomannomutase activity (14.3%) phosphoglucosamine mutase activity (14.3%)" "IPR005844 (10.4%) IPR016066 (10.4%) IPR050060 (10.4%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10.4%) Alpha-D-phosphohexomutase, conserved site (10.4%) Phosphoglucosamine mutase (10.4%)" YYALLDLQYDNGFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" ATGDKEALDLALSLYHDLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.11 (100%) cellobiose epimerase (100%) GO:0005975 (48.3%) "GO:0047736 (50%) GO:0016853 (1.7%)" carbohydrate metabolic process (48.3%) "cellobiose epimerase activity (50%) isomerase activity (1.7%)" "IPR010819 (26.1%) IPR028584 (25.2%) IPR008928 (24.4%)" "N-acylglucosamine 2-epimerase/Cellobiose 2-epimerase (26.1%) Cellobiose 2-epimerase (25.2%) Six-hairpin glycosidase superfamily (24.4%)" SYAVNFLLQDEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0006432 (16.4%) GO:0006412 (0.3%)" "GO:0009328 (16.4%) GO:0005737 (0.3%)" "GO:0000049 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" "phenylalanyl-tRNA aminoacylation (16.4%) translation (0.3%)" "phenylalanine-tRNA ligase complex (16.4%) cytoplasm (0.3%)" "tRNA binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005121 (8%) IPR005147 (7.8%) IPR041616 (7.8%)" "Ferrodoxin-fold anticodon-binding domain (8%) tRNA synthetase, B5-domain (7.8%) Phenylalanyl tRNA synthetase beta chain, core domain (7.8%)" DKDFTEYLYPATMHQTMLFFTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.8%) IPR005743 (12.8%) IPR006691 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA gyrase, subunit A (12.8%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%)" EYQGLEPLNTSEFMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (32.4%) IPR010230 (32.4%) IPR027417 (32.4%)" "ABC transporter-like, ATP-binding domain (32.4%) FeS cluster assembly SUF system, ATPase SufC (32.4%) P-loop containing nucleoside triphosphate hydrolase (32.4%)" VDLTETVDGWFVPTMPDLNQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" VESWLDRDYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0001681 (50%) carbohydrate metabolic process (50%) sialate O-acetylesterase activity (50%) "IPR005181 (34%) IPR039329 (34%) IPR036514 (32%)" "Sialate O-acetylesterase domain (34%) Sialate O-acetylesterase (34%) SGNH hydrolase superfamily (32%)" LASMLTEYTLDVFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006353 (19.5%) GO:0031564 (19.5%)" GO:0005829 (19.5%) "GO:0003723 (19.5%) GO:0003700 (19.2%) GO:0003746 (2.3%)" "DNA-templated transcription termination (19.5%) transcription antitermination (19.5%)" cytosol (19.5%) "RNA binding (19.5%) DNA-binding transcription factor activity (19.2%) translation elongation factor activity (2.3%)" "IPR025249 (12.1%) IPR030842 (12.1%) IPR009019 (12%)" "Transcription factor NusA, first KH domain (12.1%) Transcription factor NusA, prokaryotes (12.1%) K homology domain superfamily, prokaryotic type (12%)" NSNLQYDMHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YKLGLFSDPYR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (31.7%) GO:0005975 (1.9%)" GO:0042597 (32.7%) GO:0008422 (33.7%) "glucan catabolic process (31.7%) carbohydrate metabolic process (1.9%)" periplasmic space (32.7%) beta-glucosidase activity (33.7%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" EAWEFLDHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.2%) IPR006235 (17.2%) IPR054542 (17.2%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.2%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.2%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (17.2%)" NYDQHLLFEGYNEMLDADNTWNAPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (25%) GO:0006080 (25%) GO:0030245 (6.3%)" "GO:0005576 (6.3%) GO:0009986 (6.3%)" "GO:0016985 (25%) GO:0008422 (6.3%)" "polysaccharide catabolic process (25%) substituted mannan metabolic process (25%) cellulose catabolic process (6.3%)" "extracellular region (6.3%) cell surface (6.3%)" "mannan endo-1,4-beta-mannosidase activity (25%) beta-glucosidase activity (6.3%)" "IPR001547 (26.3%) IPR017853 (23.7%) IPR022790 (23.7%)" "Glycoside hydrolase, family 5 (26.3%) Glycoside hydrolase superfamily (23.7%) Glycosyl hydrolase family 26 domain (23.7%)" VVLLDFHLFASK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (22.4%) GO:0030313 (20.9%) "GO:0016209 (26.9%) GO:0016491 (26.9%) GO:0004601 (3%)" cytochrome complex assembly (22.4%) cell envelope (20.9%) "antioxidant activity (26.9%) oxidoreductase activity (26.9%) peroxidase activity (3%)" "IPR000866 (24.7%) IPR025380 (23.5%) IPR036249 (23.5%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (24.7%) Domain of unknown function DUF4369 (23.5%) Thioredoxin-like superfamily (23.5%)" ESVLSSEALGDLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20%) GO:0019676 (20%)" "GO:0051538 (20%) GO:0046872 (19.5%) GO:0015930 (14.7%)" "glutamate biosynthetic process (20%) ammonia assimilation cycle (20%)" "3 iron, 4 sulfur cluster binding (20%) metal ion binding (19.5%) glutamate synthase activity (14.7%)" "IPR006982 (12.9%) IPR017932 (12.9%) IPR050711 (12.9%)" "Glutamate synthase, central-N (12.9%) Glutamine amidotransferase type 2 domain (12.9%) Electron transfer and nitrogen metabolism enzyme (12.9%)" QAFNYLK root "2.3.1.179 (60%) 2.7.7.101 (20%) 2.7.7.19 (20%)" "beta-ketoacyl-[acyl-carrier-protein] synthase II (60%) DNA primase DnaG (20%) polynucleotide adenylyltransferase (20%)" "GO:0006508 (3.4%) GO:0007018 (2.8%) GO:0032259 (1.7%)" "GO:0016020 (5.6%) GO:0005737 (5.1%) GO:0005829 (2.8%)" "GO:0005524 (3.4%) GO:0000981 (2.8%) GO:0045505 (2.8%)" "proteolysis (3.4%) microtubule-based movement (2.8%) methylation (1.7%)" "membrane (5.6%) cytoplasm (5.1%) cytosol (2.8%)" "ATP binding (3.4%) DNA-binding transcription factor activity, RNA polymerase II-specific (2.8%) dynein intermediate chain binding (2.8%)" "IPR025393 (4.1%) IPR029044 (4.1%) IPR024269 (2.5%)" "Domain of unknown function DUF4301 (4.1%) Nucleotide-diphospho-sugar transferases (4.1%) Protein of unknown function DUF3791 (2.5%)" SFDEPLSDYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (20%) GO:0009099 (20%)" GO:0005829 (20%) "GO:0003984 (20%) GO:1990610 (20%)" "isoleucine biosynthetic process (20%) L-valine biosynthetic process (20%)" cytosol (20%) "acetolactate synthase activity (20%) acetolactate synthase regulator activity (20%)" "IPR019455 (15.2%) IPR027271 (15.2%) IPR045865 (15.2%)" "Acetolactate synthase, small subunit, C-terminal (15.2%) Acetolactate synthase/Transcription factor NikR, C-terminal (15.2%) ACT-like domain (15.2%)" LACPPLVYGCPFLNFTSSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (20%) GO:0006164 (12%) GO:0006189 (8%)" "GO:0004044 (20%) GO:0046872 (20%) GO:0051536 (20%)" "purine nucleobase biosynthetic process (20%) purine nucleotide biosynthetic process (12%) 'de novo' IMP biosynthetic process (8%)" "amidophosphoribosyltransferase activity (20%) metal ion binding (20%) iron-sulfur cluster binding (20%)" "IPR000836 (21.2%) IPR017932 (20.5%) IPR029057 (19.9%)" "Phosphoribosyltransferase domain (21.2%) Glutamine amidotransferase type 2 domain (20.5%) Phosphoribosyltransferase-like (19.9%)" RNALLENVTVAADGK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.7%) GO:0005829 (17.7%) "GO:0004612 (17.7%) GO:0005524 (17.7%) GO:0046872 (17.7%)" gluconeogenesis (17.7%) cytosol (17.7%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.7%) ATP binding (17.7%) metal ion binding (17.7%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" FTPGHTLQATYCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" ANEEASYQAAPLKPEVSFDDFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" LMLVASEGGWEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR000757 (20%) IPR013320 (20%) IPR013783 (20%)" "Beta-glucanase-like, N-terminal domain (20%) Concanavalin A-like lectin/glucanase domain superfamily (20%) Immunoglobulin-like fold (20%)" LVLVNEEGKPMYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" MANLDKLEVLAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" VMSSELEASVEEESR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.8%) IPR005743 (12.8%) IPR006691 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA gyrase, subunit A (12.8%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%)" GGAGGDEAALFAGDLFNMYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006415 (2.1%) GO:0005737 (48.9%) GO:0016149 (48.9%) translational termination (2.1%) cytoplasm (48.9%) translation release factor activity, codon specific (48.9%) "IPR005139 (20.5%) IPR050057 (20.5%) IPR000352 (19.7%)" "Peptide chain release factor (20.5%) Prokaryotic/Mitochondrial Release Factor (20.5%) Peptide chain release factor class I (19.7%)" TGDDYNQLLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (45.2%) GO:0006811 (4.8%)" GO:0009279 (50%) "iron ion transport (45.2%) monoatomic ion transport (4.8%)" cell outer membrane (50%) "IPR000531 (25.6%) IPR012910 (25.6%) IPR039426 (25.6%)" "TonB-dependent receptor-like, beta-barrel (25.6%) TonB-dependent receptor, plug domain (25.6%) TonB-dependent receptor-like (25.6%)" ALENECYVALAGSVGNLPR Bacteria Bacteria "2.3.1.- (50%) 3.5.1.100 (35.7%) 3.5.-.- (7.1%)" "Transferring groups other than amino-acyl groups (50%) (R)-amidase (35.7%) Acting on carbon-nitrogen bonds, other than peptide bonds (7.1%)" "GO:0016747 (60%) GO:0016787 (39.2%) GO:0000257 (0.8%)" "acyltransferase activity, transferring groups other than amino-acyl groups (60%) hydrolase activity (39.2%) nitrilase activity (0.8%)" "IPR003010 (21.3%) IPR000182 (21%) IPR036526 (21%)" "Carbon-nitrogen hydrolase (21.3%) GNAT domain (21%) Carbon-nitrogen hydrolase superfamily (21%)" SVTLYALR root 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (16%) GO:0015949 (15.7%) GO:0006882 (1.6%)" "GO:0005829 (15.7%) GO:0016020 (2.2%) GO:0005737 (0.3%)" "GO:0005524 (16%) GO:0036431 (16%) GO:0036430 (7.2%)" "pyrimidine nucleotide metabolic process (16%) nucleobase-containing small molecule interconversion (15.7%) intracellular zinc ion homeostasis (1.6%)" "cytosol (15.7%) membrane (2.2%) cytoplasm (0.3%)" "ATP binding (16%) dCMP kinase activity (16%) CMP kinase activity (7.2%)" "IPR003136 (27%) IPR011994 (27%) IPR027417 (27%)" "Cytidylate kinase (27%) Cytidylate kinase domain (27%) P-loop containing nucleoside triphosphate hydrolase (27%)" GQLLAWR root "3.4.11.- (40%) 1.3.8.6 (14.3%) 3.4.11.7 (14.3%)" "Aminopeptidases (40%) glutaryl-CoA dehydrogenase (ETF) (14.3%) glutamyl aminopeptidase (14.3%)" "GO:0019646 (5.8%) GO:0006508 (3.7%) GO:0043171 (3.6%)" "GO:0005886 (14.8%) GO:0016020 (4.4%) GO:0005737 (3.8%)" "GO:0004129 (5.8%) GO:0008270 (3.8%) GO:0042277 (3.6%)" "aerobic electron transport chain (5.8%) proteolysis (3.7%) peptide catabolic process (3.6%)" "plasma membrane (14.8%) membrane (4.4%) cytoplasm (3.8%)" "cytochrome-c oxidase activity (5.8%) zinc ion binding (3.8%) peptide binding (3.6%)" "IPR000298 (4.5%) IPR013833 (4.5%) IPR024791 (4.5%)" "Cytochrome c oxidase subunit III-like (4.5%) Cytochrome c oxidase, subunit III, 4-helical bundle (4.5%) Cytochrome c oxidase subunit III (4.5%)" RDLLLSLLTLK Bacteria Bacteria "2.1.2.3 (90.8%) 3.5.4.10 (9.2%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (90.8%) IMP cyclohydrolase (9.2%)" "GO:0006189 (24.8%) GO:0006164 (0.2%)" "GO:0005829 (24.8%) GO:0005840 (0.2%)" "GO:0003937 (25%) GO:0004643 (25%)" "'de novo' IMP biosynthetic process (24.8%) purine nucleotide biosynthetic process (0.2%)" "cytosol (24.8%) ribosome (0.2%)" "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (25.3%) IPR016193 (25.1%) IPR024051 (25.1%)" "Bifunctional purine biosynthesis protein PurH-like (25.3%) Cytidine deaminase-like (25.1%) AICAR transformylase, duplicated domain superfamily (25.1%)" SYDHQLVDKSAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0000049 (20%) GO:0003735 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "tRNA binding (20%) structural constituent of ribosome (20%)" "IPR001848 (25%) IPR018268 (25%) IPR027486 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10, conserved site (25%) Small ribosomal subunit protein uS10 domain (25%)" ENVALQDLALFLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR045957 (78.3%) IPR011990 (21.7%)" "Domain of unknown function DUF6377 (78.3%) Tetratricopeptide-like helical domain superfamily (21.7%)" DAYTVAGER Bacteria Bacteria "3.5.1.2 (50%) 6.3.5.13 (50%)" "glutaminase (50%) lipid II isoglutaminyl synthase (glutamine-hydrolyzing) (50%)" "GO:0006412 (15.6%) GO:0042254 (15.1%) GO:0008360 (0.9%)" "GO:0005737 (15.6%) GO:0015935 (15.1%) GO:0005840 (0.5%)" "GO:0003735 (15.6%) GO:0019843 (15.1%) GO:0004359 (0.9%)" "translation (15.6%) ribosome biogenesis (15.1%) regulation of cell shape (0.9%)" "cytoplasm (15.6%) small ribosomal subunit (15.1%) ribosome (0.5%)" "structural constituent of ribosome (15.6%) rRNA binding (15.1%) glutaminase activity (0.9%)" "IPR000851 (14%) IPR005324 (14%) IPR013810 (14%)" "Small ribosomal subunit protein uS5 (14%) Small ribosomal subunit protein uS5, C-terminal (14%) Small ribosomal subunit protein uS5, N-terminal (14%)" FPVVVSDK root "GO:0005975 (43.6%) GO:0016485 (2.1%) GO:0031998 (2.1%)" GO:0005777 (2.1%) "GO:0004553 (45.7%) GO:0004252 (2.1%)" "carbohydrate metabolic process (43.6%) protein processing (2.1%) regulation of fatty acid beta-oxidation (2.1%)" peroxisome (2.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (45.7%) serine-type endopeptidase activity (2.1%)" "IPR008979 (9.6%) IPR013783 (9.6%) IPR006102 (7.5%)" "Galactose-binding-like domain superfamily (9.6%) Immunoglobulin-like fold (9.6%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.5%)" PTAEELEAFEPDFVVYNASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.6%) GO:0005829 (17.6%) "GO:0004612 (17.6%) GO:0005524 (17.6%) GO:0046872 (17.6%)" gluconeogenesis (17.6%) cytosol (17.6%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.6%) ATP binding (17.6%) metal ion binding (17.6%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" KHSFTAMLGQEAWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR039426 (14.8%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent receptor-like (14.8%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" WCTWWGNELVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.4%) IPR002469 (25.4%) IPR050278 (25.4%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.4%) Dipeptidylpeptidase IV, N-terminal domain (25.4%) Serine protease S9B/DPPIV (25.4%)" RNNQFWYQEAMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.4%) IPR003385 (20.4%) IPR013783 (19.7%)" "Carbohydrate binding module family 20 (20.4%) Glycoside hydrolase, family 77 (20.4%) Immunoglobulin-like fold (19.7%)" ALEYNQQYMDKNPNAAPTDFMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.8%) IPR011990 (47.2%)" "Tetratricopeptide repeat (52.8%) Tetratricopeptide-like helical domain superfamily (47.2%)" YNFGLFLSGPSK Bacteroidota Bacteria Pseudomonadati Bacteroidota "IPR003741 (33.3%) IPR024185 (33.3%) IPR037171 (33.3%)" "LUD domain (33.3%) 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily (33.3%) NagB/RpiA transferase-like (33.3%)" NMVDALDEMQLLNLGTYVLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) TASYTLAMGYDNMHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48%) GO:0005737 (48%)" "GO:0008237 (2%) GO:0016787 (2%)" "extracellular region (48%) cytoplasm (48%)" "metallopeptidase activity (2%) hydrolase activity (2%)" "IPR050708 (18.8%) IPR022385 (18.1%) IPR006530 (14.5%)" "Type VI secretion system VgrG/RHS (18.8%) Rhs repeat-associated core (18.1%) YD repeat (14.5%)" YVEHEDFNEDVLAGADLLYMTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (16.7%) GO:0006520 (16.7%) GO:0044205 (16.7%)" GO:0005829 (16.7%) "GO:0004070 (16.7%) GO:0016597 (16.7%)" "'de novo' pyrimidine nucleobase biosynthetic process (16.7%) amino acid metabolic process (16.7%) 'de novo' UMP biosynthetic process (16.7%)" cytosol (16.7%) "aspartate carbamoyltransferase activity (16.7%) amino acid binding (16.7%)" "IPR002082 (20%) IPR006130 (20%) IPR006131 (20%)" "Aspartate carbamoyltransferase (20%) Aspartate/ornithine carbamoyltransferase (20%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20%)" LTWSHYYELLK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0003676 (100%) nucleic acid binding (100%) "IPR009362 (25.9%) IPR041527 (25.9%) IPR053148 (25.9%)" "YhcG PDDEXK nuclease domain (25.9%) YhcG, N-terminal (25.9%) PD-(D/E)XK-like domain-containing protein (25.9%)" KMEDLLEQTYEACK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (83.3%) GO:0016740 (16.7%)" "glycosyltransferase activity (83.3%) transferase activity (16.7%)" "IPR000836 (26.2%) IPR017932 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (26.2%) Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%)" LKTELEDLSFR Bacteria Bacteria "2.7.6.5 (52.9%) 3.1.7.2 (47.1%)" "GTP diphosphokinase (52.9%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (47.1%)" "GO:0015969 (26.8%) GO:0042594 (8%) GO:0015949 (7.5%)" GO:0005886 (27%) "GO:0008893 (9.7%) GO:0008728 (8.8%) GO:0016301 (7.5%)" "guanosine tetraphosphate metabolic process (26.8%) response to starvation (8%) nucleobase-containing small molecule interconversion (7.5%)" plasma membrane (27%) "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (9.7%) GTP diphosphokinase activity (8.8%) kinase activity (7.5%)" "IPR007685 (9.1%) IPR003607 (8.9%) IPR004095 (8.9%)" "RelA/SpoT (9.1%) HD/PDEase domain (8.9%) TGS (8.9%)" QLLPNAGVGYR Pseudomonadati Bacteria Pseudomonadati GO:0019867 (100%) outer membrane (100%) "IPR000184 (77.1%) IPR036709 (22.9%)" "Bacterial surface antigen (D15) (77.1%) Autotransporter beta-domain superfamily (22.9%)" PSTSHSLDKVLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (25%) IPR011250 (25%) IPR036737 (25%)" "OmpA-like domain (25%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (25%) OmpA-like domain superfamily (25%)" FLAGAEAYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0042274 (16.2%) GO:0042254 (0.3%)" "GO:0005737 (16.5%) GO:0016020 (0.7%)" "GO:0003924 (16.5%) GO:0005525 (16.5%) GO:0019843 (16.5%)" "ribosomal small subunit biogenesis (16.2%) ribosome biogenesis (0.3%)" "cytoplasm (16.5%) membrane (0.7%)" "GTPase activity (16.5%) GTP binding (16.5%) rRNA binding (16.5%)" "IPR004881 (16.8%) IPR010914 (16.8%) IPR031944 (16.8%)" "Ribosome biogenesis GTPase RsgA (16.8%) RsgA GTPase domain (16.8%) Ribosome biogenesis GTPase RsgA, N-terminal (16.8%)" TTTYNAGLDFTALNGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" YVQSSGFEYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QPTLLSDTEAQQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) IPR008757 (100%) Peptidase M6-like, domain (100%) RWGLASETLNK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.9%) IPR033985 (33.9%) IPR011990 (32.2%)" "RagB/SusD domain (33.9%) SusD-like, N-terminal (33.9%) Tetratricopeptide-like helical domain superfamily (32.2%)" WALDYLGK Pseudomonadati Bacteria Pseudomonadati GO:0000271 (25%) GO:0016020 (25%) "GO:0005524 (25%) GO:0016747 (25%)" polysaccharide biosynthetic process (25%) membrane (25%) "ATP binding (25%) acyltransferase activity, transferring groups other than amino-acyl groups (25%)" "IPR029492 (92%) IPR002656 (4%) IPR050879 (4%)" "Domain of unknown function DUF4435 (92%) Acyltransferase 3 domain (4%) Acyltransferase 3 (4%)" EDVLTSVHVDEYSLDVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (8.8%) IPR007645 (8.8%) IPR010243 (8.8%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.8%) RNA polymerase Rpb2, domain 3 (8.8%) DNA-directed RNA polymerase beta subunit, bacterial-type (8.8%)" FDYATALK root "3.5.1.28 (81.8%) 3.1.-.- (9.1%) 3.2.1.4 (9.1%)" "N-acetylmuramoyl-L-alanine amidase (81.8%) Acting on ester bonds (9.1%) cellulase (9.1%)" "GO:0009253 (5.3%) GO:0009254 (5.3%) GO:0071555 (5.3%)" "GO:0005576 (23.2%) GO:0005737 (23.2%) GO:0005615 (5.3%)" "GO:0004867 (5.3%) GO:0008745 (5.3%) GO:0004197 (1.1%)" "peptidoglycan catabolic process (5.3%) peptidoglycan turnover (5.3%) cell wall organization (5.3%)" "extracellular region (23.2%) cytoplasm (23.2%) extracellular space (5.3%)" "serine-type endopeptidase inhibitor activity (5.3%) N-acetylmuramoyl-L-alanine amidase activity (5.3%) cysteine-type endopeptidase activity (1.1%)" "IPR022045 (10.3%) IPR006530 (10%) IPR050708 (9.6%)" "Insecticide toxin TcdB middle/N-terminal (10.3%) YD repeat (10%) Type VI secretion system VgrG/RHS (9.6%)" TPSFLPVYHNDLTTALTGYSGFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" FVMMDDSMWGMLLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.3.1 (50%) 6.4.1.1 (50%)" "methylmalonyl-CoA carboxytransferase (50%) pyruvate carboxylase (50%)" GO:0006094 (32.9%) GO:0005737 (32.9%) "GO:0004736 (32.9%) GO:0047154 (0.9%) GO:0016740 (0.4%)" gluconeogenesis (32.9%) cytoplasm (32.9%) "pyruvate carboxylase activity (32.9%) methylmalonyl-CoA carboxytransferase activity (0.9%) transferase activity (0.4%)" "IPR003379 (21.1%) IPR000891 (20.8%) IPR055268 (20.8%)" "Carboxylase, conserved domain (21.1%) Pyruvate carboxyltransferase (20.8%) Pyruvate carboxylase-like (20.8%)" RYVLNPWGPAACFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LGQVLTMK root 2.7.2.11 (100%) glutamate 5-kinase (100%) "GO:0055129 (21.5%) GO:0006561 (1.3%)" "GO:0005829 (22.8%) GO:0005886 (1.3%) GO:0016593 (1.3%)" "GO:0004349 (22.8%) GO:0005524 (22.8%) GO:0003723 (3.8%)" "L-proline biosynthetic process (21.5%) obsolete proline biosynthetic process (1.3%)" "cytosol (22.8%) plasma membrane (1.3%) Cdc73/Paf1 complex (1.3%)" "glutamate 5-kinase activity (22.8%) ATP binding (22.8%) RNA binding (3.8%)" "IPR001048 (15.7%) IPR005715 (15.7%) IPR041739 (14.8%)" "Aspartate/glutamate/uridylate kinase (15.7%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (15.7%) Glutamate-5-kinase domain (14.8%)" SLDFTGGR root "2.1.1.72 (66.7%) 2.7.7.7 (33.3%)" "site-specific DNA-methyltransferase (adenine-specific) (66.7%) DNA-directed DNA polymerase (33.3%)" "GO:0006605 (18.7%) GO:0043952 (18.7%) GO:0065002 (18.7%)" "GO:0005886 (19.9%) GO:0005739 (0.5%) GO:0009898 (0.1%)" "GO:0015450 (19.8%) GO:0050660 (0.5%) GO:0003995 (0.4%)" "protein targeting (18.7%) protein transport by the Sec complex (18.7%) intracellular protein transmembrane transport (18.7%)" "plasma membrane (19.9%) mitochondrion (0.5%) cytoplasmic side of plasma membrane (0.1%)" "protein-transporting ATPase activity (19.8%) flavin adenine dinucleotide binding (0.5%) acyl-CoA dehydrogenase activity (0.4%)" "IPR022646 (11%) IPR022813 (11%) IPR048634 (10.9%)" "Protein-export membrane protein SecD/SecF/SecDF, conserved site (11%) Protein-export membrane protein SecD/SecF, archaeal and bacterial (11%) Protein export membrane protein SecD/SecF, C-terminal (10.9%)" GLDCEASCPVVFDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" GRMEEPDLLVECLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.3%) GO:0015941 (14.3%)" GO:0071513 (14.3%) "GO:0004632 (14.3%) GO:0004633 (14.3%) GO:0010181 (14.3%)" "coenzyme A biosynthetic process (14.3%) pantothenate catabolic process (14.3%)" phosphopantothenoylcysteine decarboxylase complex (14.3%) "phosphopantothenate--cysteine ligase activity (14.3%) phosphopantothenoylcysteine decarboxylase activity (14.3%) FMN binding (14.3%)" "IPR003382 (20.7%) IPR005252 (20.7%) IPR007085 (20.7%)" "Flavoprotein (20.7%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.7%) DNA/pantothenate metabolism flavoprotein, C-terminal (20.7%)" FTGNLLWCTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (29.8%) GO:0009279 (40.4%) GO:0015344 (29.8%) siderophore transmembrane transport (29.8%) cell outer membrane (40.4%) siderophore uptake transmembrane transporter activity (29.8%) "IPR000531 (44.1%) IPR036942 (32.2%) IPR039426 (23.7%)" "TonB-dependent receptor-like, beta-barrel (44.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.2%) TonB-dependent receptor-like (23.7%)" AAGAMLSGMLAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.4%) GO:0019676 (19.4%)" "GO:0046872 (19.4%) GO:0051538 (19.4%) GO:0004355 (9.7%)" "glutamate biosynthetic process (19.4%) ammonia assimilation cycle (19.4%)" "metal ion binding (19.4%) 3 iron, 4 sulfur cluster binding (19.4%) glutamate synthase (NADPH) activity (9.7%)" "IPR002489 (13.3%) IPR002932 (13.3%) IPR006982 (13.3%)" "Glutamate synthase, alpha subunit, C-terminal (13.3%) Glutamate synthase domain (13.3%) Glutamate synthase, central-N (13.3%)" QFTLTNLR root 2.7.10.1 (100%) receptor protein-tyrosine kinase (100%) "GO:0045493 (36.2%) GO:0042593 (2.9%) GO:0043410 (2.9%)" "GO:0005899 (2.9%) GO:0030424 (2.9%)" "GO:0004553 (37.7%) GO:0005009 (2.9%) GO:0005524 (2.9%)" "xylan catabolic process (36.2%) glucose homeostasis (2.9%) positive regulation of MAPK cascade (2.9%)" "insulin receptor complex (2.9%) axon (2.9%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (37.7%) insulin receptor activity (2.9%) ATP binding (2.9%)" "IPR000421 (13.2%) IPR006710 (13.2%) IPR008979 (13.2%)" "Coagulation factor 5/8, C-terminal domain (13.2%) Glycoside hydrolase, family 43 (13.2%) Galactose-binding-like domain superfamily (13.2%)" QLDFTLAGDSAPVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (25%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (25%)" "IPR001900 (12.7%) IPR003029 (12.7%) IPR004476 (12.7%)" "Ribonuclease II/R (12.7%) S1 domain (12.7%) Ribonuclease II/ribonuclease R (12.7%)" LTTLSGSNNYQTSDFWMYSTDAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" YTPGEPVQLFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (2.2%) "GO:0000155 (24.4%) GO:0003700 (24.4%) GO:0005524 (24.4%)" membrane (2.2%) "phosphorelay sensor kinase activity (24.4%) DNA-binding transcription factor activity (24.4%) ATP binding (24.4%)" "IPR001789 (6.9%) IPR003594 (6.9%) IPR003661 (6.9%)" "Signal transduction response regulator, receiver domain (6.9%) Histidine kinase/HSP90-like ATPase domain (6.9%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.9%)" AFPGEENLSVVVGHDCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.8%) IPR016066 (14.8%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.8%) Alpha-D-phosphohexomutase, conserved site (14.8%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" KSQLTLTAGVLAQTDAENYTEYNDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) SLEEGQMVNAGTTLTYLLPTNNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0055085 (50%) GO:0016020 (50%) transmembrane transport (50%) membrane (50%) "IPR043602 (37.7%) IPR050739 (37.7%) IPR032317 (24.5%)" "Unknown (37.7%) Membrane Fusion Protein (37.7%) Unknown (24.5%)" VNLNLLGLFPQTADSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011250 (40%) IPR027385 (14.3%) IPR006664 (11.4%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (40%) Outer membrane protein, beta-barrel domain (14.3%) Outer membrane protein, bacterial (11.4%)" MWWDENLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25.3%) GO:0005737 (25.3%) "GO:0004134 (25.3%) GO:2001070 (24.1%)" carbohydrate metabolic process (25.3%) cytoplasm (25.3%) "4-alpha-glucanotransferase activity (25.3%) starch binding (24.1%)" "IPR003385 (21.3%) IPR002044 (20.2%) IPR017853 (20.2%)" "Glycoside hydrolase, family 77 (21.3%) Carbohydrate binding module family 20 (20.2%) Glycoside hydrolase superfamily (20.2%)" KGGLGGLSDGGLTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) SLYHLLKPELNFEPGTSEYDPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) LYLELGGK root 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) "GO:0006508 (5.3%) GO:0006302 (2.6%) GO:0006538 (2.6%)" "GO:0005886 (5.3%) GO:0005634 (2.6%) GO:0005737 (2.6%)" "GO:0004030 (13.2%) GO:0016887 (7.9%) GO:0005524 (5.3%)" "proteolysis (5.3%) double-strand break repair (2.6%) L-glutamate catabolic process (2.6%)" "plasma membrane (5.3%) nucleus (2.6%) cytoplasm (2.6%)" "aldehyde dehydrogenase [NAD(P)+] activity (13.2%) ATP hydrolysis activity (7.9%) ATP binding (5.3%)" "IPR048496 (31.8%) IPR048441 (26.1%) IPR014999 (3.3%)" "DUF1846, N-terminal domain (31.8%) DUF1846, C-terminal (26.1%) Family of unknown function DUF1846 (3.3%)" LPLGLQDFEEMRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (62.9%) IPR012547 (37.1%)" "AAA-ATPase-like domain (62.9%) PD-(D/E)XK nuclease superfamily 9 (37.1%)" AMVYGFQGEDPNNLDQYHLATSMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" LVVAPADGK Bacteria Bacteria "4.1.1.65 (99.4%) 2.7.1.199 (0.6%)" "phosphatidylserine decarboxylase (99.4%) protein-N(pi)-phosphohistidine--D-glucose phosphotransferase (0.6%)" "GO:0006646 (29.3%) GO:0008654 (4%)" GO:0005886 (33.3%) GO:0004609 (33.3%) "phosphatidylethanolamine biosynthetic process (29.3%) phospholipid biosynthetic process (4%)" plasma membrane (33.3%) phosphatidylserine decarboxylase activity (33.3%) "IPR003817 (50%) IPR033175 (50%)" "Phosphatidylserine decarboxylase-related (50%) Phosphatidylserine decarboxylase, prokaryotes (50%)" DLNDAVVK root 4.1.1.21 (100%) phosphoribosylaminoimidazole carboxylase (100%) "GO:0043113 (3.6%) GO:0045197 (3.6%) GO:0098609 (3.6%)" "GO:0005886 (20.9%) GO:0005912 (3.6%) GO:0014069 (3.6%)" "GO:0003755 (20%) GO:0019901 (3.6%) GO:0046872 (2.7%)" "receptor clustering (3.6%) establishment or maintenance of epithelial cell apical/basal polarity (3.6%) cell-cell adhesion (3.6%)" "plasma membrane (20.9%) adherens junction (3.6%) postsynaptic density (3.6%)" "peptidyl-prolyl cis-trans isomerase activity (20%) protein kinase binding (3.6%) metal ion binding (2.7%)" "IPR052029 (13.3%) IPR027304 (12.7%) IPR046357 (12.7%)" "Periplasmic chaperone PpiD (13.3%) Trigger factor/SurA domain superfamily (12.7%) Peptidyl-prolyl cis-trans isomerase domain superfamily (12.7%)" DMLTYEGQDVNELRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (100%) regulation of DNA-templated transcription (100%) "IPR008651 (33.3%) IPR010985 (33.3%) IPR035069 (33.3%)" "Uncharacterised protein family HicB (33.3%) Ribbon-helix-helix (33.3%) Antitoxin HicB/UPF0150 (33.3%)" GTFPLDKFQELQTPFYYYDTNVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.8%) "GO:0008836 (33.8%) GO:0030170 (32.4%)" lysine biosynthetic process via diaminopimelate (33.8%) "diaminopimelate decarboxylase activity (33.8%) pyridoxal phosphate binding (32.4%)" "IPR002986 (14.5%) IPR022643 (14.5%) IPR022644 (14.5%)" "Diaminopimelate decarboxylase, LysA (14.5%) Orn/DAP/Arg decarboxylase 2, C-terminal (14.5%) Orn/DAP/Arg decarboxylase 2, N-terminal (14.5%)" AVEAEGADSVSLLNTLMGMAVDLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.3.-.- (92.9%) 1.3.1.14 (7.1%)" "Acting on the CH-CH group of donors (92.9%) dihydroorotate dehydrogenase (NAD(+)) (7.1%)" "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" EAVEREPLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SLTNWNNLLLGLTNPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) GPLLVWK root "6.1.1.15 (62.5%) 2.7.11.1 (37.5%)" "proline--tRNA ligase (62.5%) non-specific serine/threonine protein kinase (37.5%)" "GO:0006433 (4.5%) GO:0032527 (2.7%) GO:0089718 (2.7%)" "GO:0005886 (15.3%) GO:0016020 (8.1%) GO:0005739 (4.5%)" "GO:0004827 (4.5%) GO:0005524 (4.5%) GO:0016787 (3.6%)" "prolyl-tRNA aminoacylation (4.5%) protein exit from endoplasmic reticulum (2.7%) amino acid import across plasma membrane (2.7%)" "plasma membrane (15.3%) membrane (8.1%) mitochondrion (4.5%)" "proline-tRNA ligase activity (4.5%) ATP binding (4.5%) hydrolase activity (3.6%)" "IPR003790 (9.4%) IPR052177 (9.4%) IPR013783 (9%)" "Glycosyl hydrolase-like 10 (9.4%) Divisome-localized Glycosyl Hydrolase (9.4%) Immunoglobulin-like fold (9%)" EASADGLNWTFSPMVDLALDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR026891 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Fibronectin type III-like domain (11.5%)" FSLDAAPDATLTLTYVGMEPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (5.6%) GO:0009279 (88.9%) GO:0015344 (5.6%) siderophore transmembrane transport (5.6%) cell outer membrane (88.9%) siderophore uptake transmembrane transporter activity (5.6%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023997 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" VGEALGNETLEYGCDLVLGPGMNLHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.5%) IPR002772 (12.5%) IPR013783 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (12.5%) Glycoside hydrolase family 3 C-terminal domain (12.5%) Immunoglobulin-like fold (12.5%)" NLTQMYR root "GO:0007264 (11.1%) GO:0015031 (11.1%) GO:0016192 (11.1%)" "GO:0016020 (14.8%) GO:0005737 (11.1%) GO:0016604 (3.7%)" "GO:0004222 (14.8%) GO:0005093 (11.1%) GO:0008146 (3.7%)" "small GTPase-mediated signal transduction (11.1%) protein transport (11.1%) vesicle-mediated transport (11.1%)" "membrane (14.8%) cytoplasm (11.1%) nuclear body (3.7%)" "metalloendopeptidase activity (14.8%) Rab GDP-dissociation inhibitor activity (11.1%) sulfotransferase activity (3.7%)" "IPR016047 (38.4%) IPR011055 (36.6%) IPR050570 (3.6%)" "M23ase, beta-sheet core domain (38.4%) Duplicated hybrid motif (36.6%) Bacterial cell wall metabolism enzyme (3.6%)" SYSSGFLMPTYGDETAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (50%) GO:1990351 (50%)" "cell outer membrane (50%) transporter complex (50%)" "IPR045659 (50%) IPR050218 (50%)" "LPS-assembly protein LptD, central domain (50%) Lipopolysaccharide Assembly Protein LptD (50%)" AFMLSADNAHAWHPNYSEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.6%) GO:0005737 (19.2%) "GO:0004177 (20.6%) GO:0008270 (20.6%) GO:0008237 (19.2%)" proteolysis (20.6%) cytoplasm (19.2%) "aminopeptidase activity (20.6%) zinc ion binding (20.6%) metallopeptidase activity (19.2%)" "IPR001948 (51.8%) IPR023358 (48.2%)" "Peptidase M18 (51.8%) Peptidase M18, domain 2 (48.2%)" LAYYLFK root "2.1.1.- (16.7%) 2.7.11.1 (16.7%) 3.4.23.36 (16.7%)" "Methyltransferases (16.7%) non-specific serine/threonine protein kinase (16.7%) signal peptidase II (16.7%)" "GO:0032259 (6.9%) GO:0006744 (1.1%) GO:0007155 (1.1%)" "GO:0016020 (29.4%) GO:0005886 (12.2%) GO:0005730 (0.9%)" "GO:0008168 (6.4%) GO:0005524 (6%) GO:0016887 (3%)" "methylation (6.9%) ubiquinone biosynthetic process (1.1%) cell adhesion (1.1%)" "membrane (29.4%) plasma membrane (12.2%) nucleolus (0.9%)" "methyltransferase activity (6.4%) ATP binding (6%) ATP hydrolysis activity (3%)" "IPR019185 (7.7%) IPR029063 (6%) IPR045957 (4.7%)" "Integral membrane protein SYS1-related (7.7%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (6%) Domain of unknown function DUF6377 (4.7%)" SYDHQLVDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0000049 (20%) GO:0003735 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "tRNA binding (20%) structural constituent of ribosome (20%)" "IPR001848 (25%) IPR018268 (25%) IPR027486 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10, conserved site (25%) Small ribosomal subunit protein uS10 domain (25%)" LNLDSDSR root "4.1.2.13 (97%) 3.1.-.- (0.9%) 4.1.2.- (0.9%)" "fructose-bisphosphate aldolase (97%) Acting on ester bonds (0.9%) Aldehyde-lyases (0.9%)" "GO:0006096 (20.9%) GO:0030388 (20.9%) GO:0005975 (3.4%)" "GO:0016020 (0.5%) GO:0005737 (0.4%) GO:0005829 (0.1%)" "GO:0008270 (24.7%) GO:0004332 (21.7%) GO:0016832 (2.5%)" "glycolytic process (20.9%) fructose 1,6-bisphosphate metabolic process (20.9%) carbohydrate metabolic process (3.4%)" "membrane (0.5%) cytoplasm (0.4%) cytosol (0.1%)" "zinc ion binding (24.7%) fructose-bisphosphate aldolase activity (21.7%) aldehyde-lyase activity (2.5%)" "IPR000771 (24.2%) IPR050246 (24.2%) IPR013785 (24.1%)" "Fructose-bisphosphate aldolase, class-II (24.2%) Class II Fructose-bisphosphate Aldolase (24.2%) Aldolase-type TIM barrel (24.1%)" MNFSMDYFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" LNASNLTVSDVFDALEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (33.3%) IPR004763 (33.3%) IPR027463 (33.3%)" "Acriflavin resistance protein (33.3%) Cation efflux system CusA-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%)" WSNLHADGSTQHDQNYSDTDFPMFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (53.8%) IPR011990 (46.2%)" "RagB/SusD domain (53.8%) Tetratricopeptide-like helical domain superfamily (46.2%)" ANGADVVLLDTAGR Bacteria Bacteria 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) "GO:0006614 (16.4%) GO:0051301 (1.6%)" "GO:0005737 (16.4%) GO:0005886 (16.4%)" "GO:0003924 (16.4%) GO:0005047 (16.4%) GO:0005525 (16.4%)" "SRP-dependent cotranslational protein targeting to membrane (16.4%) cell division (1.6%)" "cytoplasm (16.4%) plasma membrane (16.4%)" "GTPase activity (16.4%) signal recognition particle binding (16.4%) GTP binding (16.4%)" "IPR000897 (14.4%) IPR003593 (14.4%) IPR004390 (14.4%)" "Signal recognition particle, SRP54 subunit, GTPase domain (14.4%) AAA+ ATPase domain (14.4%) Signal-recognition particle receptor FtsY (14.4%)" KLVNEVYLDEK Pseudomonadati Bacteria Pseudomonadati "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.5%) IPR027417 (25.5%) IPR050764 (25.5%)" "ATPase, AAA-3 (25.5%) P-loop containing nucleoside triphosphate hydrolase (25.5%) CbbQ/NirQ/NorQ/GpvN (25.5%)" YFASADFVHEGDLFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023997 (15.1%) IPR039426 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%) TonB-dependent receptor-like (15.1%)" LEQLEWFNPYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" xylan catabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (17.2%) IPR006584 (17.2%) IPR006710 (17.2%)" "Carbohydrate binding module family 6 (17.2%) Cellulose binding, type IV (17.2%) Glycoside hydrolase, family 43 (17.2%)" ANNFQNEVCWER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (75%) IPR033985 (25%)" "Tetratricopeptide-like helical domain superfamily (75%) SusD-like, N-terminal (25%)" NAWLSANVSGYYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) DGHLLSTFR root 3.5.99.2 (100%) aminopyrimidine aminohydrolase (100%) GO:0009228 (50%) GO:0016787 (50%) thiamine biosynthetic process (50%) hydrolase activity (50%) "IPR001214 (25%) IPR044238 (25%) IPR046341 (25%)" "SET domain (25%) Histone-lysine N-methyltransferase ASHR2-like (25%) SET domain superfamily (25%)" LSNETPASGTVLTPSLVLKPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032339 (100%) Domain of unknown function DUF4859 (100%) HGAASTLFGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (100%) plasma membrane (100%) "IPR032816 (50%) IPR051311 (50%)" "VTT domain (50%) DedA domain-containing protein (50%)" VLNLTTNLGDEWRPTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006304 (17%) GO:0005829 (17%) "GO:0003677 (17%) GO:0005524 (17%) GO:0016787 (17%)" DNA modification (17%) cytosol (17%) "DNA binding (17%) ATP binding (17%) hydrolase activity (17%)" "IPR006935 (17%) IPR013670 (17%) IPR014001 (17%)" "Helicase/UvrB, N-terminal (17%) EcoEI R protein C-terminal domain (17%) Helicase superfamily 1/2, ATP-binding domain (17%)" STLLNLLGLLDNPTSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (16.7%) IPR003593 (16.7%) IPR015854 (16.7%)" "ABC transporter-like, ATP-binding domain (16.7%) AAA+ ATPase domain (16.7%) ABC transporter, lipoprotein release, LolD-like (16.7%)" MVNLGVDWNLWNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" DMESVLEEAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.3%) "GO:0008836 (33.3%) GO:0030170 (33.3%)" lysine biosynthetic process via diaminopimelate (33.3%) "diaminopimelate decarboxylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000183 (14.3%) IPR002986 (14.3%) IPR009006 (14.3%)" "Ornithine/DAP/Arg decarboxylase (14.3%) Diaminopimelate decarboxylase, LysA (14.3%) Alanine racemase/group IV decarboxylase, C-terminal (14.3%)" AQLLDAVK root "2.7.7.7 (45.2%) 1.1.1.95 (25%) 1.1.1.290 (6%)" "DNA-directed DNA polymerase (45.2%) phosphoglycerate dehydrogenase (25%) 4-phosphoerythronate dehydrogenase (6%)" "GO:0006261 (4.9%) GO:0006508 (1.7%) GO:0000902 (1.1%)" "GO:0009360 (4.9%) GO:0005737 (1.4%) GO:0005794 (1.1%)" "GO:0051287 (23.9%) GO:0016616 (19.3%) GO:0003677 (4.9%)" "DNA-templated DNA replication (4.9%) proteolysis (1.7%) cell morphogenesis (1.1%)" "DNA polymerase III complex (4.9%) cytoplasm (1.4%) Golgi apparatus (1.1%)" "NAD binding (23.9%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (19.3%) DNA binding (4.9%)" "IPR036291 (16.4%) IPR006140 (16.1%) IPR006139 (16%)" "NAD(P)-binding domain superfamily (16.4%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (16.1%) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (16%)" AFAWNADGTALGWLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.-.- (50%) 3.4.14.5 (50%)" "Acting on peptide bonds (peptidases) (50%) dipeptidyl-peptidase IV (50%)" GO:0006508 (34%) "GO:0008239 (34%) GO:0008236 (32%)" proteolysis (34%) "dipeptidyl-peptidase activity (34%) serine-type peptidase activity (32%)" "IPR002469 (26%) IPR050278 (26%) IPR001375 (24.4%)" "Dipeptidylpeptidase IV, N-terminal domain (26%) Serine protease S9B/DPPIV (26%) Peptidase S9, prolyl oligopeptidase, catalytic domain (24.4%)" LDYFSDAAYLEEQAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" YFATLKPGLNVLLPFLDHAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20%) IPR001972 (20%) IPR018080 (20%)" "Band 7 domain (20%) Stomatin/HflK family (20%) Band 7/stomatin-like, conserved site (20%)" LMVESDMAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (33.9%) "GO:0008446 (33.9%) GO:0070401 (32.2%)" 'de novo' GDP-L-fucose biosynthetic process (33.9%) "GDP-mannose 4,6-dehydratase activity (33.9%) NADP+ binding (32.2%)" "IPR006368 (33.9%) IPR016040 (33.9%) IPR036291 (32.2%)" "GDP-mannose 4,6-dehydratase (33.9%) NAD(P)-binding domain (33.9%) NAD(P)-binding domain superfamily (32.2%)" VLNLPSWDFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (9.5%) IPR006103 (9.5%) IPR006104 (9.5%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.5%) Glycoside hydrolase family 2, catalytic domain (9.5%) Glycosyl hydrolases family 2, sugar binding domain (9.5%)" SSALYSGNLTLLPDLQADFVYCVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.5%) IPR012944 (33.3%) IPR011990 (32.1%)" "SusD-like, N-terminal (34.5%) RagB/SusD domain (33.3%) Tetratricopeptide-like helical domain superfamily (32.1%)" LQLCSLR root "6.1.1.12 (56.3%) 1.8.4.9 (29.6%) 2.7.11.1 (4.2%)" "aspartate--tRNA ligase (56.3%) adenylyl-sulfate reductase (glutathione) (29.6%) non-specific serine/threonine protein kinase (4.2%)" "GO:0006422 (5.7%) GO:0019344 (2.8%) GO:0019379 (2.8%)" "GO:0005737 (15.3%) GO:0009507 (2.4%) GO:0016020 (1.8%)" "GO:0005524 (6.6%) GO:0004815 (5.7%) GO:0003676 (5.4%)" "aspartyl-tRNA aminoacylation (5.7%) cysteine biosynthetic process (2.8%) sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (2.8%)" "cytoplasm (15.3%) chloroplast (2.4%) membrane (1.8%)" "ATP binding (6.6%) aspartate-tRNA ligase activity (5.7%) nucleic acid binding (5.4%)" "IPR032675 (4.1%) IPR001611 (3.4%) IPR004364 (3%)" "Leucine-rich repeat domain superfamily (4.1%) Leucine-rich repeat (3.4%) Aminoacyl-tRNA synthetase, class II (D/K/N) (3%)" LLENQMAQQQLEASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (24.4%) GO:0030313 (24.4%) "GO:0016209 (24.4%) GO:0016491 (24.4%) GO:0004601 (2.2%)" cytochrome complex assembly (24.4%) cell envelope (24.4%) "antioxidant activity (24.4%) oxidoreductase activity (24.4%) peroxidase activity (2.2%)" "IPR000866 (26.1%) IPR036249 (26.1%) IPR025380 (23.9%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (26.1%) Thioredoxin-like superfamily (26.1%) Domain of unknown function DUF4369 (23.9%)" KYLDEHDALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.3%) IPR003156 (9.3%) IPR012947 (9.3%)" "Alanine-tRNA ligase, class IIc (9.3%) DHHA1 domain (9.3%) Threonyl/alanyl tRNA synthetase, SAD (9.3%)" LALGDPAGNSSVLSDRYVEDGSYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LVGLYYNLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.11 (100%) glutamate 5-kinase (100%) "GO:0055129 (23.2%) GO:0006561 (1.8%)" GO:0005829 (25%) "GO:0004349 (25%) GO:0005524 (25%)" "L-proline biosynthetic process (23.2%) obsolete proline biosynthetic process (1.8%)" cytosol (25%) "glutamate 5-kinase activity (25%) ATP binding (25%)" "IPR001048 (18.4%) IPR005715 (18.4%) IPR041739 (17.1%)" "Aspartate/glutamate/uridylate kinase (18.4%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (18.4%) Glutamate-5-kinase domain (17.1%)" GQYLHVDNTSDAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR002035 (25.3%) IPR024163 (25.3%) IPR050768 (25.3%)" "von Willebrand factor, type A (25.3%) Aerotolerance regulator, N-terminal (25.3%) UPF0353/GerABKA protein families (25.3%)" TGNLQNHYLAFSGGTPQSNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023997 (14.7%) IPR039426 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%) TonB-dependent receptor-like (14.7%)" MVECGHDVVLFLDSLTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.4.- (98.9%) 3.6.1.- (1.1%)" "Acting on ATP; involved in cellular and subcellular movement (98.9%) In phosphorus-containing anhydrides (1.1%)" GO:0006353 (14.4%) GO:0005829 (13.9%) "GO:0003723 (14.4%) GO:0005524 (14.4%) GO:0008186 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.9%) "RNA binding (14.4%) ATP binding (14.4%) ATP-dependent activity, acting on RNA (14.4%)" "IPR004665 (11.3%) IPR000194 (11.2%) IPR003593 (11.1%)" "Transcription termination factor Rho (11.3%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (11.2%) AAA+ ATPase domain (11.1%)" KGLLSLTANYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.3%) IPR019819 (20.3%) IPR050309 (20.3%)" "Carboxylesterase, type B (20.3%) Carboxylesterase type B, conserved site (20.3%) Type-B Carboxylesterase/Lipase (20.3%)" FTTAFPLR root "GO:0015679 (14.2%) GO:0060003 (14.2%) GO:0008610 (3.3%)" "GO:0016020 (16.4%) GO:0030313 (14.2%) GO:0005794 (1.6%)" "GO:0022857 (14.2%) GO:0003824 (3.3%) GO:0031177 (3.3%)" "plasma membrane copper ion transport (14.2%) copper ion export (14.2%) lipid biosynthetic process (3.3%)" "membrane (16.4%) cell envelope (14.2%) Golgi apparatus (1.6%)" "transmembrane transporter activity (14.2%) catalytic activity (3.3%) phosphopantetheine binding (3.3%)" "IPR032317 (15.9%) IPR006143 (14.8%) IPR051909 (14.8%)" "Unknown (15.9%) RND efflux pump, membrane fusion protein (14.8%) Membrane Fusion Protein Cation Efflux System (14.8%)" LDMPATSNVLQWFCDDNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.6%) IPR005845 (14.6%) IPR005846 (14.6%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.6%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.6%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (14.6%)" NSEQLPDFKDYSMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (24.7%) GO:0045493 (24.7%) GO:0005975 (0.7%)" "GO:0009044 (24.7%) GO:0046556 (24.7%) GO:0004553 (0.7%)" "arabinan catabolic process (24.7%) xylan catabolic process (24.7%) carbohydrate metabolic process (0.7%)" "xylan 1,4-beta-xylosidase activity (24.7%) alpha-L-arabinofuranosidase activity (24.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (0.7%)" "IPR002772 (9.5%) IPR026891 (9.5%) IPR011658 (9.3%)" "Glycoside hydrolase family 3 C-terminal domain (9.5%) Fibronectin type III-like domain (9.5%) PA14 domain (9.3%)" GSAGQSFGAFLVK root "1.4.1.13 (56.8%) 1.4.1.14 (40%) 1.4.7.1 (3.2%)" "glutamate synthase (NADPH) (56.8%) glutamate synthase (NADH) (40%) glutamate synthase (ferredoxin) (3.2%)" "GO:0019676 (15.9%) GO:0006537 (11.2%) GO:0097054 (5.6%)" GO:0009570 (0.4%) "GO:0051538 (16.7%) GO:0046872 (11.8%) GO:0015930 (9.1%)" "ammonia assimilation cycle (15.9%) glutamate biosynthetic process (11.2%) L-glutamate biosynthetic process (5.6%)" chloroplast stroma (0.4%) "3 iron, 4 sulfur cluster binding (16.7%) metal ion binding (11.8%) glutamate synthase activity (9.1%)" "IPR002489 (9.9%) IPR002932 (9.9%) IPR013785 (9.7%)" "Glutamate synthase, alpha subunit, C-terminal (9.9%) Glutamate synthase domain (9.9%) Aldolase-type TIM barrel (9.7%)" KVTPSDELCVSSVGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" TAADAAEALGLGLQAFCLPGSVADDRK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR025964 (100%) GGGtGRT protein (100%) LWNQPSR root "GO:0005975 (38.3%) GO:0010411 (2.1%) GO:0080120 (2.1%)" "GO:0016020 (4.3%) GO:0009536 (2.1%)" "GO:0004650 (38.3%) GO:0004557 (4.3%) GO:0003676 (2.1%)" "carbohydrate metabolic process (38.3%) xyloglucan metabolic process (2.1%) CAAX-box protein maturation (2.1%)" "membrane (4.3%) plastid (2.1%)" "polygalacturonase activity (38.3%) alpha-galactosidase activity (4.3%) nucleic acid binding (2.1%)" "IPR000743 (11.5%) IPR006626 (11.5%) IPR010905 (11.5%)" "Glycoside hydrolase, family 28 (11.5%) Parallel beta-helix repeat (11.5%) Glycosyl hydrolase, family 88 (11.5%)" KLDYPGLQWFNGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" AVLESVGLK root "GO:0006412 (16.1%) GO:0042254 (14.5%)" "GO:0005737 (16.7%) GO:0015935 (15.1%) GO:0005840 (1.1%)" "GO:0003735 (16.1%) GO:0019843 (15.1%) GO:0003723 (1.1%)" "translation (16.1%) ribosome biogenesis (14.5%)" "cytoplasm (16.7%) small ribosomal subunit (15.1%) ribosome (1.1%)" "structural constituent of ribosome (16.1%) rRNA binding (15.1%) RNA binding (1.1%)" "IPR000851 (14.2%) IPR005324 (14.2%) IPR013810 (14.2%)" "Small ribosomal subunit protein uS5 (14.2%) Small ribosomal subunit protein uS5, C-terminal (14.2%) Small ribosomal subunit protein uS5, N-terminal (14.2%)" VGGALVEDSEQLAQLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.8 (100%) acetylglutamate kinase (100%) GO:0042450 (25%) GO:0005737 (25%) "GO:0003991 (25%) GO:0005524 (25%)" L-arginine biosynthetic process via ornithine (25%) cytoplasm (25%) "acetylglutamate kinase activity (25%) ATP binding (25%)" "IPR001048 (25%) IPR004662 (25%) IPR036393 (25%)" "Aspartate/glutamate/uridylate kinase (25%) Acetylglutamate kinase family (25%) Acetylglutamate kinase-like superfamily (25%)" MLLSQLLHMPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.- (100%) Methyltransferases (100%) GO:0032259 (25.3%) "GO:0005840 (25.3%) GO:0005737 (24.1%)" "GO:0008276 (24.1%) GO:0016279 (1.1%)" methylation (25.3%) "ribosome (25.3%) cytoplasm (24.1%)" "protein methyltransferase activity (24.1%) protein-lysine N-methyltransferase activity (1.1%)" "IPR029063 (33.8%) IPR050078 (33.8%) IPR004498 (32.3%)" "S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.8%) Ribosomal protein L11 methyltransferase PrmA (33.8%) Ribosomal protein L11 methyltransferase (32.3%)" EWAPNATDLYLLGDFNNWQETEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (18.8%) GO:0005975 (1.3%)" GO:0005737 (20%) "GO:0003844 (20%) GO:0004553 (20%) GO:0043169 (20%)" "glycogen biosynthetic process (18.8%) carbohydrate metabolic process (1.3%)" cytoplasm (20%) "1,4-alpha-glucan branching enzyme activity (20%) hydrolase activity, hydrolyzing O-glycosyl compounds (20%) cation binding (20%)" "IPR004193 (13%) IPR006047 (13%) IPR006048 (13%)" "Glycoside hydrolase, family 13, N-terminal (13%) Glycosyl hydrolase family 13, catalytic domain (13%) Alpha-amylase/branching enzyme, C-terminal all beta (13%)" LHGVSQSTYFLHNVNAYNEGALTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016491 (50%) GO:0051536 (50%)" "oxidoreductase activity (50%) iron-sulfur cluster binding (50%)" "IPR009051 (25%) IPR023753 (25%) IPR028261 (25%)" "Alpha-helical ferredoxin (25%) FAD/NAD(P)-binding domain (25%) Dihydroprymidine dehydrogenase domain II (25%)" VGFNWDVLGNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (32%) GO:0009279 (36%) GO:0015344 (32%) siderophore transmembrane transport (32%) cell outer membrane (36%) siderophore uptake transmembrane transporter activity (32%) "IPR057601 (24.3%) IPR036942 (21.6%) IPR039426 (21.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (24.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (21.6%) TonB-dependent receptor-like (21.6%)" GAQEAHEALRPTYMNEPTLEGTAQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.6%) "GO:0003677 (25.6%) GO:0003917 (25.6%) GO:0046872 (23.1%)" DNA topological change (25.6%) "DNA binding (25.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.6%) metal ion binding (23.1%)" "IPR000380 (7.5%) IPR003602 (7.5%) IPR013497 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, DNA-binding domain (7.5%) DNA topoisomerase, type IA, central (7.5%)" GEPVQYVLGEADFAGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.1.1.297 (97%) 2.1.1.- (3%)" "peptide chain release factor N(5)-glutamine methyltransferase (97%) Methyltransferases (3%)" GO:0032259 (23.9%) "GO:0003676 (23.9%) GO:0008276 (18.1%) GO:0008170 (14.5%)" methylation (23.9%) "nucleic acid binding (23.9%) protein methyltransferase activity (18.1%) N-methyltransferase activity (14.5%)" "IPR002052 (14.4%) IPR004556 (14.4%) IPR019874 (14.4%)" "DNA methylase, N-6 adenine-specific, conserved site (14.4%) Methyltransferase HemK-like (14.4%) Release factor glutamine methyltransferase (14.4%)" ADHNLHLGCDFDVMAYGNYTQLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" RVDELLAK root "2.1.1.360 (31.8%) 3.5.1.5 (9.1%) 6.3.1.2 (9.1%)" "[histone H3]-lysine(79) N-trimethyltransferase (31.8%) urease (9.1%) glutamine synthetase (9.1%)" "GO:0006542 (5.5%) GO:0032259 (2.2%) GO:0000077 (1.9%)" "GO:0042597 (17.2%) GO:0016020 (6.6%) GO:0005634 (3.6%)" "GO:0004356 (5.7%) GO:0005524 (4.1%) GO:0016887 (2.2%)" "glutamine biosynthetic process (5.5%) methylation (2.2%) DNA damage checkpoint signaling (1.9%)" "periplasmic space (17.2%) membrane (6.6%) nucleus (3.6%)" "glutamine synthetase activity (5.7%) ATP binding (4.1%) ATP hydrolysis activity (2.2%)" "IPR006059 (9.5%) IPR050490 (9.5%) IPR008146 (3.2%)" "Bacterial-type extracellular solute-binding protein (9.5%) Bacterial solute-binding protein 1 (9.5%) Glutamine synthetase, catalytic domain (3.2%)" EYLYSLLEK root 2.7.7.48 (100%) RNA-directed RNA polymerase (100%) "GO:0019062 (6.6%) GO:0039654 (6.6%) GO:0075512 (6.6%)" "GO:0016020 (9.8%) GO:0019031 (6.6%) GO:0020002 (6.6%)" "GO:0005198 (6.6%) GO:0016757 (6.6%) GO:0046872 (3.3%)" "virion attachment to host cell (6.6%) fusion of virus membrane with host endosome membrane (6.6%) clathrin-dependent endocytosis of virus by host cell (6.6%)" "membrane (9.8%) viral envelope (6.6%) host cell plasma membrane (6.6%)" "structural molecule activity (6.6%) glycosyltransferase activity (6.6%) metal ion binding (3.3%)" "IPR001173 (22.9%) IPR029044 (22.9%) IPR000328 (11.4%)" "Glycosyltransferase 2-like (22.9%) Nucleotide-diphospho-sugar transferases (22.9%) Retroviral envelope protein GP41-like (11.4%)" LPDDASETLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0043039 (17.2%) GO:0009313 (13.4%)" "GO:0004812 (17.2%) GO:0005524 (17.2%) GO:0046872 (16.2%)" "tRNA aminoacylation (17.2%) oligosaccharide catabolic process (13.4%)" "aminoacyl-tRNA ligase activity (17.2%) ATP binding (17.2%) metal ion binding (16.2%)" "IPR012947 (26.7%) IPR018163 (25.7%) IPR006047 (20.8%)" "Threonyl/alanyl tRNA synthetase, SAD (26.7%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (25.7%) Glycosyl hydrolase family 13, catalytic domain (20.8%)" SNSSTTVFSDTGVQTSLQMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (50.6%) GO:0016787 (49.4%)" "carbohydrate binding (50.6%) hydrolase activity (49.4%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" GDNLDYVVNSSSSLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.2 (100%) acid phosphatase (100%) "GO:0003993 (48.8%) GO:0046872 (48.8%) GO:0016787 (2.3%)" "acid phosphatase activity (48.8%) metal ion binding (48.8%) hydrolase activity (2.3%)" "IPR004843 (25.6%) IPR051558 (25.6%) IPR024927 (24.4%)" "Calcineurin-like, phosphoesterase domain (25.6%) Metallophosphoesterase Purple Acid Phosphatase (25.6%) Purple acid phosphatase (24.4%)" HALDTSLETLYLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella DLDYFMFGHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.1.54 (100%) UDP-2,3-diacylglucosamine diphosphatase (100%) GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0008758 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) UDP-2,3-diacylglucosamine hydrolase activity (33.3%) "IPR043461 (51.1%) IPR029052 (48.9%)" "UDP-2,3-diacylglucosamine hydrolase LpxH-like (51.1%) Metallo-dependent phosphatase-like (48.9%)" FLNNLHLALSVNNLCTLTGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SPCLLFLDELDAVGR root "3.4.24.- (99.6%) 2.7.7.8 (0.1%) 3.5.4.16 (0.1%)" "Metalloendopeptidases (99.6%) polyribonucleotide nucleotidyltransferase (0.1%) GTP cyclohydrolase I (0.1%)" "GO:0006508 (11.3%) GO:0030163 (10.7%) GO:0051301 (3%)" "GO:0005886 (10.4%) GO:0005745 (0.8%) GO:0009535 (0.4%)" "GO:0005524 (12.1%) GO:0016887 (12.1%) GO:0004176 (12.1%)" "proteolysis (11.3%) protein catabolic process (10.7%) cell division (3%)" "plasma membrane (10.4%) m-AAA complex (0.8%) chloroplast thylakoid membrane (0.4%)" "ATP binding (12.1%) ATP hydrolysis activity (12.1%) ATP-dependent peptidase activity (12.1%)" "IPR003959 (11.1%) IPR027417 (11%) IPR003593 (11%)" "ATPase, AAA-type, core (11.1%) P-loop containing nucleoside triphosphate hydrolase (11%) AAA+ ATPase domain (11%)" VQELTEVLPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" RGQLHEVLR root 2.4.1.21 (100%) starch synthase (100%) "GO:0016757 (90.5%) GO:0009011 (6.3%) GO:0004373 (3.2%)" "glycosyltransferase activity (90.5%) alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity (6.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (3.2%)" "IPR013534 (98.4%) IPR011029 (0.8%) IPR027417 (0.8%)" "Starch synthase, catalytic domain (98.4%) Death-like domain superfamily (0.8%) P-loop containing nucleoside triphosphate hydrolase (0.8%)" HATQTNYSSYGLPTQHAEVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009313 (16.5%) GO:0043039 (16.5%)" "GO:0004556 (16.5%) GO:0004812 (16.5%) GO:0005524 (16.5%)" "oligosaccharide catabolic process (16.5%) tRNA aminoacylation (16.5%)" "alpha-amylase activity (16.5%) aminoacyl-tRNA ligase activity (16.5%) ATP binding (16.5%)" "IPR006047 (25.6%) IPR012947 (25.6%) IPR017853 (24.4%)" "Glycosyl hydrolase family 13, catalytic domain (25.6%) Threonyl/alanyl tRNA synthetase, SAD (25.6%) Glycoside hydrolase superfamily (24.4%)" SPNLYPNNYEYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VMNYLNLSMSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" AQNSSLESKDEWQELTLPFTYDNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" AGFDCDYLSDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0004553 (85.7%) GO:0016787 (14.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (85.7%) hydrolase activity (14.3%)" "IPR053161 (35%) IPR008979 (32.5%) IPR054593 (32.5%)" "Ulvan-degrading glycoside hydrolase (35%) Galactose-binding-like domain superfamily (32.5%) Beta-mannosidase-like, galactose-binding domain-like (32.5%)" LKATSVDEQTLLDEWCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" LFNFDWWK root "GO:0005975 (20.4%) GO:0045493 (12.9%)" "GO:0004553 (33.3%) GO:0030246 (33.3%)" "carbohydrate metabolic process (20.4%) xylan catabolic process (12.9%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (13.6%) IPR006584 (13.6%) IPR006710 (13.6%)" "Carbohydrate binding module family 6 (13.6%) Cellulose binding, type IV (13.6%) Glycoside hydrolase, family 43 (13.6%)" GNFDSLVAGFVETGENLEEAVHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.1.22 (100%) NAD(+) diphosphatase (100%) "GO:0006734 (16.5%) GO:0006742 (16.5%) GO:0019677 (16.5%)" GO:0005829 (16.5%) "GO:0035529 (16.5%) GO:0046872 (16.5%) GO:0110153 (0.9%)" "obsolete NADH metabolic process (16.5%) NADP+ catabolic process (16.5%) NAD+ catabolic process (16.5%)" cytosol (16.5%) "NADH pyrophosphatase activity (16.5%) metal ion binding (16.5%) RNA NAD-cap (NMN-forming) hydrolase activity (0.9%)" "IPR000086 (14.5%) IPR015375 (14.5%) IPR015376 (14.5%)" "NUDIX hydrolase domain (14.5%) NADH pyrophosphatase-like, N-terminal (14.5%) Zinc ribbon, NADH pyrophosphatase (14.5%)" NVLPLVQK root 3.2.1.14 (100%) chitinase (100%) "GO:0005975 (15.4%) GO:0000272 (6.7%) GO:0006032 (6.7%)" "GO:0005576 (4.8%) GO:0005737 (1.9%) GO:0005874 (1.9%)" "GO:0008422 (14.4%) GO:0004568 (4.8%) GO:0004553 (2.9%)" "carbohydrate metabolic process (15.4%) polysaccharide catabolic process (6.7%) chitin catabolic process (6.7%)" "extracellular region (4.8%) cytoplasm (1.9%) microtubule (1.9%)" "beta-glucosidase activity (14.4%) chitinase activity (4.8%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.9%)" "IPR017853 (10.3%) IPR001764 (7.1%) IPR002772 (7.1%)" "Glycoside hydrolase superfamily (10.3%) Glycoside hydrolase, family 3, N-terminal (7.1%) Glycoside hydrolase family 3 C-terminal domain (7.1%)" SETFGYNELSPEYTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (30%) GO:0009279 (36.7%) GO:0015344 (33.3%) siderophore transmembrane transport (30%) cell outer membrane (36.7%) siderophore uptake transmembrane transporter activity (33.3%) "IPR036942 (50.8%) IPR039426 (47.6%) IPR057601 (1.6%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50.8%) TonB-dependent receptor-like (47.6%) TonB-dependent transporter Oar-like, beta-barrel domain (1.6%)" YLLFSDLHGCLPALEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.4.- (100%) Phosphoric diester hydrolases (100%) GO:0005737 (21.1%) "GO:0046872 (39.5%) GO:0016791 (21.1%) GO:0016787 (18.4%)" cytoplasm (21.1%) "metal ion binding (39.5%) phosphatase activity (21.1%) hydrolase activity (18.4%)" "IPR000979 (28.3%) IPR024654 (28.3%) IPR029052 (28.3%)" "Phosphodiesterase MJ0936/Vps29 (28.3%) Calcineurin-like phosphoesterase domain, lpxH-type (28.3%) Metallo-dependent phosphatase-like (28.3%)" LVGVPYNMFVWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.6%) IPR012910 (20.6%) IPR039426 (20.6%)" "TonB-dependent receptor-like, beta-barrel (20.6%) TonB-dependent receptor, plug domain (20.6%) TonB-dependent receptor-like (20.6%)" QALDGDTAQVGPQVAQK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009055 (100%) electron transfer activity (100%) "IPR012255 (20.1%) IPR014729 (20.1%) IPR014730 (20.1%)" "Electron transfer flavoprotein, beta subunit (20.1%) Rossmann-like alpha/beta/alpha sandwich fold (20.1%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (20.1%)" AATFTLGADMMEGESK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (74%) "GO:0016787 (24%) GO:0016829 (2%)" carbohydrate metabolic process (74%) "hydrolase activity (24%) lyase activity (2%)" "IPR013783 (25.3%) IPR031965 (24.1%) IPR017853 (23.5%)" "Immunoglobulin-like fold (25.3%) Starch-binding module 26 (24.1%) Glycoside hydrolase superfamily (23.5%)" VYASALTTLLLDNHNYLPTTDNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (33.6%) IPR027417 (32.8%) IPR018163 (31%)" "Phosphoribulokinase/uridine kinase (33.6%) P-loop containing nucleoside triphosphate hydrolase (32.8%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (31%)" ELQAEMAAELAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.23 (100%) orotidine-5'-phosphate decarboxylase (100%) "GO:0006207 (33.3%) GO:0044205 (33.3%)" GO:0004590 (33.3%) "'de novo' pyrimidine nucleobase biosynthetic process (33.3%) 'de novo' UMP biosynthetic process (33.3%)" orotidine-5'-phosphate decarboxylase activity (33.3%) "IPR001754 (26.3%) IPR011995 (26.3%) IPR011060 (23.7%)" "Orotidine 5'-phosphate decarboxylase domain (26.3%) Orotidine 5'-phosphate decarboxylase, type 2 (26.3%) Ribulose-phosphate binding barrel (23.7%)" NTDAPEVLEQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.7.4.8 (95.5%) 2.7.-.- (4.5%)" "guanylate kinase (95.5%) Transferring phosphorus-containing groups (4.5%)" GO:0005829 (33.9%) "GO:0004385 (33.9%) GO:0005524 (32.3%)" cytosol (33.9%) "GMP kinase activity (33.9%) ATP binding (32.3%)" "IPR008144 (20.6%) IPR008145 (20.6%) IPR017665 (19.6%)" "Guanylate kinase-like domain (20.6%) Guanylate kinase/L-type calcium channel beta subunit (20.6%) Guanylate kinase (19.6%)" KLTGAPLYLDDTPGLSVFELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.3 (100%) DNA 5'-3' helicase (100%) "GO:0006269 (12%) GO:0006260 (1.1%)" "GO:0005829 (13%) GO:1990077 (12%)" "GO:0003678 (13%) GO:0005524 (13%) GO:0003677 (12%)" "DNA replication, synthesis of primer (12%) DNA replication (1.1%)" "cytosol (13%) primosome complex (12%)" "DNA helicase activity (13%) ATP binding (13%) DNA binding (12%)" "IPR007694 (15.8%) IPR007692 (14.5%) IPR007693 (14.5%)" "DNA helicase, DnaB-like, C-terminal (15.8%) DNA helicase, DnaB type (14.5%) DNA helicase, DnaB-like, N-terminal (14.5%)" TEHLNKFPHQLAYNVLPQLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (10.6%) GO:0009089 (10.6%) GO:0009097 (10.6%)" "GO:0046983 (11.8%) GO:0051287 (11.8%) GO:0004073 (10.6%)" "threonine biosynthetic process (10.6%) lysine biosynthetic process via diaminopimelate (10.6%) isoleucine biosynthetic process (10.6%)" "protein dimerization activity (11.8%) NAD binding (11.8%) aspartate-semialdehyde dehydrogenase activity (10.6%)" "IPR000534 (21.3%) IPR012280 (21.3%) IPR036291 (21.3%)" "Semialdehyde dehydrogenase, NAD-binding (21.3%) Semialdehyde dehydrogenase, dimerisation domain (21.3%) NAD(P)-binding domain superfamily (21.3%)" AEELLAFMGLSDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0044874 (16%) GO:0089705 (16%)" GO:0005886 (17%) "GO:0005524 (17%) GO:0016887 (17%) GO:0022857 (17%)" "lipoprotein localization to outer membrane (16%) protein localization to outer membrane (16%)" plasma membrane (17%) "ATP binding (17%) ATP hydrolysis activity (17%) transmembrane transporter activity (17%)" "IPR003439 (17.1%) IPR015854 (17.1%) IPR017871 (16.6%)" "ABC transporter-like, ATP-binding domain (17.1%) ABC transporter, lipoprotein release, LolD-like (17.1%) ABC transporter-like, conserved site (16.6%)" EPYTVLDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.21.53 (96.8%) 3.4.21.- (3.2%)" "endopeptidase La (96.8%) Serine endopeptidases (3.2%)" "GO:0006515 (12.4%) GO:0034605 (12.4%)" GO:0005737 (12.4%) "GO:0004176 (12.4%) GO:0004252 (12.4%) GO:0005524 (12.4%)" "protein quality control for misfolded or incompletely synthesized proteins (12.4%) cellular response to heat (12.4%)" cytoplasm (12.4%) "ATP-dependent peptidase activity (12.4%) serine-type endopeptidase activity (12.4%) ATP binding (12.4%)" "IPR003111 (7.5%) IPR003593 (7.3%) IPR003959 (7.3%)" "Lon protease, N-terminal domain (7.5%) AAA+ ATPase domain (7.3%) ATPase, AAA-type, core (7.3%)" LPLEAELADFLDLFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0008299 (50%) "GO:0004659 (46.4%) GO:0106350 (3.6%)" isoprenoid biosynthetic process (50%) "prenyltransferase activity (46.4%) all-trans-octaprenyl-diphosphate synthase activity (3.6%)" "IPR000092 (34.1%) IPR033749 (34.1%) IPR008949 (31.7%)" "Polyprenyl synthetase-like (34.1%) Polyprenyl synthetase, conserved site (34.1%) Isoprenoid synthase domain superfamily (31.7%)" NMVVTFR root 1.14.16.5 (100%) alkylglycerol monooxygenase (100%) "GO:0007165 (18.2%) GO:0006643 (9.1%) GO:0008610 (9.1%)" "GO:0005789 (9.1%) GO:0016020 (9.1%)" "GO:0016747 (18.2%) GO:0005506 (9.1%) GO:0050479 (9.1%)" "signal transduction (18.2%) membrane lipid metabolic process (9.1%) lipid biosynthetic process (9.1%)" "endoplasmic reticulum membrane (9.1%) membrane (9.1%)" "acyltransferase activity, transferring groups other than amino-acyl groups (18.2%) iron ion binding (9.1%) glyceryl-ether monooxygenase activity (9.1%)" "IPR000182 (6.5%) IPR001194 (6.5%) IPR005112 (6.5%)" "GNAT domain (6.5%) cDENN domain (6.5%) dDENN domain (6.5%)" ALLNDMGFLENELRLPLVPTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25.4%) IPR005263 (25.4%) IPR020625 (25.4%)" "DapA-like (25.4%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25.4%) Schiff base-forming aldolase, active site (25.4%)" LLMQNFYSPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (37.9%) IPR012547 (32.6%) IPR027417 (29.5%)" "AAA-ATPase-like domain (37.9%) PD-(D/E)XK nuclease superfamily 9 (32.6%) P-loop containing nucleoside triphosphate hydrolase (29.5%)" DPVSSAGHADLVEDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.6%) IPR051795 (20.6%) IPR041542 (20.1%)" "Glycoside hydrolase, family 43 (20.6%) Glycosyl Hydrolase Family 43 (20.6%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.1%)" TVLNDFMNAYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.7%) IPR012944 (32.1%) IPR033985 (32.1%)" "Tetratricopeptide-like helical domain superfamily (35.7%) RagB/SusD domain (32.1%) SusD-like, N-terminal (32.1%)" ADGMEQLRPANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (19.8%) GO:0006164 (14%) GO:0006189 (5.8%)" "GO:0004044 (19.8%) GO:0046872 (19.8%) GO:0051536 (19.8%)" "purine nucleobase biosynthetic process (19.8%) purine nucleotide biosynthetic process (14%) 'de novo' IMP biosynthetic process (5.8%)" "amidophosphoribosyltransferase activity (19.8%) metal ion binding (19.8%) iron-sulfur cluster binding (19.8%)" "IPR000836 (20.6%) IPR017932 (20.6%) IPR029055 (19.8%)" "Phosphoribosyltransferase domain (20.6%) Glutamine amidotransferase type 2 domain (20.6%) Nucleophile aminohydrolases, N-terminal (19.8%)" VTMDGEDLTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" ELQVDPSQKVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (43.8%) GO:0000272 (6.3%)" "GO:0004553 (43.8%) GO:0031176 (6.3%)" "xylan catabolic process (43.8%) polysaccharide catabolic process (6.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (43.8%) endo-1,4-beta-xylanase activity (6.3%)" "IPR001000 (36.4%) IPR017853 (31.8%) IPR044846 (31.8%)" "Glycoside hydrolase family 10 domain (36.4%) Glycoside hydrolase superfamily (31.8%) Glycoside hydrolase family 10 (31.8%)" EQSDNLTEVFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0051082 (24.7%)" "ATP binding (24.7%) ATP hydrolysis activity (24.7%) unfolded protein binding (24.7%)" "IPR001404 (19.8%) IPR019805 (19.8%) IPR020568 (19.8%)" "Heat shock protein Hsp90 family (19.8%) Heat shock protein Hsp90, conserved site (19.8%) Ribosomal protein uS5 domain 2-type superfamily (19.8%)" QLLPYGLGHFSQYASQELVDANFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13.1%) IPR002772 (13.1%) IPR026891 (13.1%)" "Glycoside hydrolase, family 3, N-terminal (13.1%) Glycoside hydrolase family 3 C-terminal domain (13.1%) Fibronectin type III-like domain (13.1%)" ALWGNADFAENVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25%) IPR020845 (25%) IPR042099 (25%)" "AMP-dependent synthetase/ligase domain (25%) AMP-binding, conserved site (25%) ANL, N-terminal domain (25%)" VLEVSEATLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (51.5%) IPR042278 (48.5%)" "Fimbrillin-like 1 (51.5%) Fimbrillin-like 1, N-terminal (48.5%)" QYGGVPLKLEPSNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLFTCTYDTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VEELHGDYLEYVYDLVDEDVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.5%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.5%) "IPR003284 (18.6%) IPR028994 (16.3%) IPR022045 (13.4%)" "Salmonella virulence plasmid 65kDa B protein (18.6%) Integrin alpha, N-terminal (16.3%) Insecticide toxin TcdB middle/N-terminal (13.4%)" YKEFVDGYNQPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AAELSGDFK root "2.7.9.1 (98.4%) 2.7.-.- (1.6%)" "pyruvate, phosphate dikinase (98.4%) Transferring phosphorus-containing groups (1.6%)" GO:0035435 (0.4%) GO:0043190 (0.4%) "GO:0050242 (25.1%) GO:0016301 (24.7%) GO:0046872 (24.7%)" phosphate ion transmembrane transport (0.4%) ATP-binding cassette (ABC) transporter complex (0.4%) "pyruvate, phosphate dikinase activity (25.1%) kinase activity (24.7%) metal ion binding (24.7%)" "IPR000121 (10.1%) IPR010121 (10.1%) IPR015813 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate, phosphate dikinase (10.1%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.1%)" GLTFTPTSLSTYVNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (43.1%) "GO:0052689 (43.1%) GO:0004557 (13.7%)" cell outer membrane (43.1%) "carboxylic ester hydrolase activity (43.1%) alpha-galactosidase activity (13.7%)" "IPR032812 (25.6%) IPR044060 (25.6%) IPR011050 (24.4%)" "SbsA, Ig-like domain (25.6%) Bacterial repeat domain (25.6%) Pectin lyase fold/virulence factor (24.4%)" MLTMLMGVVDNGTAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.8%) GO:0016020 (0.4%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.8%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.8%) membrane (0.4%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.8%)" "IPR001264 (17%) IPR001460 (17%) IPR050396 (17%)" "Glycosyl transferase, family 51 (17%) Penicillin-binding protein, transpeptidase (17%) Glycosyltransferase 51/Transpeptidase (17%)" KASGMDLAAWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (10%) GO:0009279 (90%) iron ion transport (10%) cell outer membrane (90%) "IPR012910 (14.5%) IPR023996 (14.5%) IPR023997 (14.5%)" "TonB-dependent receptor, plug domain (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.5%)" NSFYELVLDNTPFYGEMGGQVGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" QADQNSLMLYSQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (46.6%) GO:0016020 (3.4%)" GO:0008381 (50%) "plasma membrane (46.6%) membrane (3.4%)" mechanosensitive monoatomic ion channel activity (50%) "IPR006685 (17.2%) IPR045275 (17.2%) IPR049278 (17.2%)" "Mechanosensitive ion channel MscS (17.2%) Mechanosensitive ion channel MscS, archaea/bacteria type (17.2%) Mechanosensitive ion channel MscS, C-terminal domain (17.2%)" FVSLLAGLDSLRDCLAFPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20.1%) GO:0005737 (20.1%) "GO:0004815 (20.1%) GO:0005524 (20.1%) GO:0003676 (19.5%)" aspartyl-tRNA aminoacylation (20.1%) cytoplasm (20.1%) "aspartate-tRNA ligase activity (20.1%) ATP binding (20.1%) nucleic acid binding (19.5%)" "IPR004364 (9.2%) IPR004524 (9.2%) IPR006195 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) Aspartate-tRNA ligase, type 1 (9.2%) Aminoacyl-tRNA synthetase, class II (9.2%)" LGGLDAYK Bacteria Bacteria "4.3.2.2 (96.6%) 1.2.4.2 (1.7%) 2.6.1.16 (1.7%)" "adenylosuccinate lyase (96.6%) oxoglutarate dehydrogenase (succinyl-transferring) (1.7%) glutamine--fructose-6-phosphate transaminase (isomerizing) (1.7%)" "GO:0006189 (20%) GO:0044208 (20%) GO:0006188 (10%)" "GO:0005829 (0.6%) GO:0045252 (0.6%)" "GO:0004018 (30%) GO:0070626 (13.3%) GO:0004360 (0.6%)" "'de novo' IMP biosynthetic process (20%) 'de novo' AMP biosynthetic process (20%) IMP biosynthetic process (10%)" "cytosol (0.6%) oxoglutarate dehydrogenase complex (0.6%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (30%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (13.3%) glutamine-fructose-6-phosphate transaminase (isomerizing) activity (0.6%)" "IPR022761 (12.2%) IPR047136 (12.2%) IPR004769 (12%)" "Fumarate lyase, N-terminal (12.2%) Adenylosuccinate lyase PurB, bacteria (12.2%) Adenylosuccinate lyase (12%)" ENVMEGVQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0006412 (12.5%) GO:0045900 (12.5%)" GO:0005737 (12.5%) "GO:0000049 (12.5%) GO:0005524 (12.5%) GO:0016887 (12.5%)" "translation (12.5%) negative regulation of translational elongation (12.5%)" cytoplasm (12.5%) "tRNA binding (12.5%) ATP binding (12.5%) ATP hydrolysis activity (12.5%)" "IPR003439 (16.7%) IPR003593 (16.7%) IPR017871 (16.7%)" "ABC transporter-like, ATP-binding domain (16.7%) AAA+ ATPase domain (16.7%) ABC transporter-like, conserved site (16.7%)" KLPELDADFEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.1.1.3 (50.9%) 2.7.2.4 (49.1%)" "homoserine dehydrogenase (50.9%) aspartate kinase (49.1%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" MGYFVDLDHPYLTYDNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" DVLSLADHALQQAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20%) GO:0048500 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0008312 (20%)" SRP-dependent cotranslational protein targeting to membrane (20%) signal recognition particle (20%) "GTPase activity (20%) GTP binding (20%) 7S RNA binding (20%)" "IPR000897 (11.1%) IPR003593 (11.1%) IPR004125 (11.1%)" "Signal recognition particle, SRP54 subunit, GTPase domain (11.1%) AAA+ ATPase domain (11.1%) Signal recognition particle, SRP54 subunit, M-domain (11.1%)" AQQSNADNMTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR019847 (100%) Gliding motility associated protein GldN (100%) LDLYLLYNGCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.7%) IPR011990 (33.3%) IPR033985 (30%)" "RagB/SusD domain (36.7%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (30%)" ANVLLNGVEQLKENGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LDFAEENDRLWGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (16.8%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.2%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (16.8%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.2%)" "IPR007081 (9.2%) IPR045867 (9.2%) IPR000722 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.2%) DNA-directed RNA polymerase, subunit beta-prime (9.2%) RNA polymerase, alpha subunit (9.1%)" YYLYDTNWQTADGYGWYDGSAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" KGNSLVEEMNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR007139 (100%) Protein of unknown function DUF349 (100%) RVMNELQDMDESHYYMLTQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) VGYDPEFGAR Pseudomonadati Bacteria Pseudomonadati "GO:0034605 (19.2%) GO:0042026 (17.2%) GO:0006508 (2.6%)" "GO:0005737 (19.2%) GO:0016020 (0.7%)" "GO:0005524 (19.2%) GO:0016887 (19.2%) GO:0008233 (2.6%)" "cellular response to heat (19.2%) protein refolding (17.2%) proteolysis (2.6%)" "cytoplasm (19.2%) membrane (0.7%)" "ATP binding (19.2%) ATP hydrolysis activity (19.2%) peptidase activity (2.6%)" "IPR003959 (8.6%) IPR019489 (8.6%) IPR050130 (8.6%)" "ATPase, AAA-type, core (8.6%) Clp ATPase, C-terminal (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%)" YVEPCHPLQFLPWDSSSFLMQSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" LPSLKNPDVLGEMTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (34.5%) IPR018163 (32.8%) IPR027417 (32.8%)" "Phosphoribulokinase/uridine kinase (34.5%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (32.8%) P-loop containing nucleoside triphosphate hydrolase (32.8%)" VLVADLGCVLYDGDQSFTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002547 (7.8%) IPR004532 (7.8%) IPR005121 (7.8%)" "tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%) Ferrodoxin-fold anticodon-binding domain (7.8%)" MMPAVLMALFTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (33.3%) "GO:0015184 (33.3%) GO:0015293 (33.3%)" plasma membrane (33.3%) "L-cystine transmembrane transporter activity (33.3%) symporter activity (33.3%)" "IPR001991 (51%) IPR036458 (49%)" "Sodium:dicarboxylate symporter (51%) Sodium:dicarboxylate symporter superfamily (49%)" EYLDELEFLADTAGAVTVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0043022 (20%)" cytoplasm (20%) "GTPase activity (20%) GTP binding (20%) ribosome binding (20%)" "IPR006073 (13.2%) IPR016496 (13.2%) IPR025121 (13.2%)" "GTP binding domain (13.2%) GTPase HflX (13.2%) GTPase HflX, N-terminal (13.2%)" QLAPFENLLLVTGENPAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009228 (25%) "GO:0005506 (25%) GO:0051539 (25%) GO:0003824 (23.8%)" thiamine biosynthetic process (25%) "iron ion binding (25%) 4 iron, 4 sulfur cluster binding (25%) catalytic activity (23.8%)" "IPR007197 (20.2%) IPR010722 (20.2%) IPR012726 (20.2%)" "Radical SAM (20.2%) Biotin and thiamin synthesis-associated domain (20.2%) Thiazole biosynthesis ThiH (20.2%)" LLAPFMTEYLTPLLPPLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002731 (25.4%) IPR018709 (25.4%) IPR051805 (25.4%)" "ATPase, BadF/BadG/BcrA/BcrD type (25.4%) CoA enzyme activase, domain of unknown function DUF2229 (25.4%) Dehydratase Activator and Reductase Protein (25.4%)" CCLNYEVDSYVEASR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" AQEQFDLEEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20%) GO:0048500 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0008312 (20%)" SRP-dependent cotranslational protein targeting to membrane (20%) signal recognition particle (20%) "GTPase activity (20%) GTP binding (20%) 7S RNA binding (20%)" "IPR000897 (11.1%) IPR003593 (11.1%) IPR004125 (11.1%)" "Signal recognition particle, SRP54 subunit, GTPase domain (11.1%) AAA+ ATPase domain (11.1%) Signal recognition particle, SRP54 subunit, M-domain (11.1%)" NLSLMNLLTMEQGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR003379 (22.9%) IPR000891 (21.9%) IPR055268 (21.9%)" "Carboxylase, conserved domain (22.9%) Pyruvate carboxyltransferase (21.9%) Pyruvate carboxylase-like (21.9%)" GQTTVGNLNFQER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EGSYVVQNPMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LTGEVPNALDSDLVQTYLTGEPGSELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (26.2%) IPR053227 (26.2%) IPR027417 (23.8%)" "NadR/Ttd14, AAA domain (26.2%) TRPL channel trafficking regulator (26.2%) P-loop containing nucleoside triphosphate hydrolase (23.8%)" DLLGANPLALQLPLGAEENFKGVVDLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0032790 (20.1%) GO:0006412 (0.4%)" GO:0005737 (19.4%) "GO:0003924 (20.1%) GO:0005525 (20.1%) GO:0003746 (19.8%)" "ribosome disassembly (20.1%) translation (0.4%)" cytoplasm (19.4%) "GTPase activity (20.1%) GTP binding (20.1%) translation elongation factor activity (19.8%)" "IPR000795 (6.5%) IPR005225 (6.5%) IPR031157 (6.5%)" "Translational (tr)-type GTP-binding domain (6.5%) Small GTP-binding domain (6.5%) Tr-type G domain, conserved site (6.5%)" RALLMGMDSEAGYQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25.2%) "GO:0003746 (25.2%) GO:0005525 (25.2%) GO:0003924 (24.4%)" ribosome disassembly (25.2%) "translation elongation factor activity (25.2%) GTP binding (25.2%) GTPase activity (24.4%)" "IPR000640 (7.9%) IPR005517 (7.9%) IPR035649 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translation elongation factor EFG/EF2, domain IV (7.9%) EFG, domain V (7.9%)" ETDAQLAENLGCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.15 (50%) 4.2.1.19 (50%)" "histidinol-phosphatase (50%) imidazoleglycerol-phosphate dehydratase (50%)" "GO:0000105 (20%) GO:0005975 (0.6%)" GO:0005737 (20%) "GO:0004401 (20%) GO:0004424 (20%) GO:0046872 (19.4%)" "L-histidine biosynthetic process (20%) carbohydrate metabolic process (0.6%)" cytoplasm (20%) "histidinol-phosphatase activity (20%) imidazoleglycerol-phosphate dehydratase activity (20%) metal ion binding (19.4%)" "IPR005954 (10.1%) IPR006543 (10.1%) IPR006549 (10.1%)" "Histidine biosynthesis bifunctional protein, N-terminal histidinol-phosphatase domain (10.1%) Histidinol-phosphate phosphatase (10.1%) HAD-superfamily hydrolase,subfamily IIIA (10.1%)" EMGLDPYPAAEFPTNAFSTDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004824 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) lysine-tRNA ligase activity (16.7%)" "IPR002313 (12.8%) IPR004364 (12.8%) IPR004365 (12.8%)" "Lysine-tRNA ligase, class II (12.8%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.8%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.8%)" YTLLFYR root "GO:1904294 (3.7%) GO:0032870 (1.5%) GO:0006897 (0.7%)" "GO:0016020 (8.9%) GO:0005886 (5.9%) GO:0000139 (0.7%)" "GO:0003700 (23.7%) GO:0043565 (23.7%) GO:0008270 (3.7%)" "positive regulation of ERAD pathway (3.7%) cellular response to hormone stimulus (1.5%) endocytosis (0.7%)" "membrane (8.9%) plasma membrane (5.9%) Golgi membrane (0.7%)" "DNA-binding transcription factor activity (23.7%) sequence-specific DNA binding (23.7%) zinc ion binding (3.7%)" "IPR018060 (19.2%) IPR009057 (18.6%) IPR037923 (16.2%)" "AraC-like, DNA binding HTH domain (19.2%) Homedomain-like superfamily (18.6%) Transcription regulator HTH-like (16.2%)" QHQNFGPSQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (32%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (32%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" VSGQNVHSTEFWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.7.8.- (87.5%) 3.1.-.- (12.5%)" "Transferases for other substituted phosphate groups (87.5%) Acting on ester bonds (12.5%)" GO:0032049 (38.2%) GO:0005886 (20.6%) "GO:0008808 (20.6%) GO:0030572 (17.6%) GO:0016787 (2.9%)" cardiolipin biosynthetic process (38.2%) plasma membrane (20.6%) "cardiolipin synthase activity (20.6%) phosphatidyltransferase activity (17.6%) hydrolase activity (2.9%)" "IPR001736 (39.4%) IPR025202 (39.4%) IPR022924 (21.2%)" "Phospholipase D/Transphosphatidylase (39.4%) Phospholipase D-like domain (39.4%) Cardiolipin synthase (21.2%)" KVLADLAVNNPEAFK Bacteria Bacteria "GO:0006412 (16.7%) GO:0000027 (16.4%)" "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" "translation (16.7%) ribosomal large subunit assembly (16.4%)" "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR005813 (33.3%) IPR035566 (33.3%) IPR049946 (33.3%)" "Large ribosomal subunit protein bL20 (33.3%) Ribosomal protein bL20, C-terminal (33.3%) Large ribosomal subunit protein bL20, conserved site (33.3%)" LDPNDYEGSLQQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR005496 (100%) Integral membrane protein TerC (100%) GFHLDPCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.4%) IPR015883 (17.4%) IPR025705 (17.4%)" "PA14 domain (17.4%) Glycoside hydrolase family 20, catalytic domain (17.4%) Beta-hexosaminidase (17.4%)" LLETLCLAVNGKPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004824 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) lysine-tRNA ligase activity (16.7%)" "IPR002313 (12.7%) IPR004364 (12.7%) IPR004365 (12.7%)" "Lysine-tRNA ligase, class II (12.7%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.7%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.7%)" VQHNNALGPYK root "1.4.1.- (75%) 1.4.1.3 (17.3%) 1.4.1.4 (5.8%)" "With NAD(+) or NADP(+) as acceptor (75%) glutamate dehydrogenase [NAD(P)(+)] (17.3%) glutamate dehydrogenase (NADP(+)) (5.8%)" "GO:0006538 (16.8%) GO:0006537 (12.6%) GO:0006103 (0.3%)" "GO:0005829 (12.6%) GO:0005737 (0.1%) GO:0009986 (0.1%)" "GO:0000166 (27.4%) GO:0004352 (16.9%) GO:0004354 (12.6%)" "L-glutamate catabolic process (16.8%) glutamate biosynthetic process (12.6%) 2-oxoglutarate metabolic process (0.3%)" "cytosol (12.6%) cytoplasm (0.1%) cell surface (0.1%)" "nucleotide binding (27.4%) glutamate dehydrogenase (NAD+) activity (16.9%) glutamate dehydrogenase (NADP+) activity (12.6%)" "IPR006097 (12%) IPR046346 (11.9%) IPR006096 (11.9%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (12%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (11.9%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.9%)" DEKYPFSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.6%) "GO:0016746 (17.1%) GO:0046872 (17.1%) GO:0051287 (17.1%)" malate metabolic process (16.6%) "acyltransferase activity (17.1%) metal ion binding (17.1%) NAD binding (17.1%)" "IPR002505 (9.2%) IPR012301 (9.2%) IPR012302 (9.2%)" "Phosphate acetyl/butaryl transferase (9.2%) Malic enzyme, N-terminal domain (9.2%) Malic enzyme, NAD-binding (9.2%)" LGQMMELVTDLFGANDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13.1%) IPR051915 (13.1%) IPR002772 (12.7%)" "Glycoside hydrolase, family 3, N-terminal (13.1%) Cellulose Degradation Glycosyl Hydrolase 3 (13.1%) Glycoside hydrolase family 3 C-terminal domain (12.7%)" LTDNFGFTGDFTYLVQHPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (92.1%) GO:0015344 (7.9%) cell outer membrane (92.1%) siderophore uptake transmembrane transporter activity (7.9%) "IPR036942 (92.1%) IPR039426 (7.9%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (92.1%) TonB-dependent receptor-like (7.9%)" DDDLPQSVASGVADLGLVGENEFVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20.1%) GO:0005737 (20.1%) "GO:0003879 (20.1%) GO:0005524 (20.1%) GO:0000287 (19.4%)" L-histidine biosynthetic process (20.1%) cytoplasm (20.1%) "ATP phosphoribosyltransferase activity (20.1%) ATP binding (20.1%) magnesium ion binding (19.4%)" "IPR001348 (14.7%) IPR013820 (14.7%) IPR011322 (14.1%)" "ATP phosphoribosyltransferase HisG (14.7%) ATP phosphoribosyltransferase, catalytic domain (14.7%) Nitrogen regulatory PII-like, alpha/beta (14.1%)" EFSLTDADYDEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (20.5%) GO:0007165 (19.6%)" GO:0030288 (19.6%) "GO:0004175 (19.6%) GO:0008236 (19.6%) GO:0008233 (0.9%)" "proteolysis (20.5%) signal transduction (19.6%)" outer membrane-bounded periplasmic space (19.6%) "endopeptidase activity (19.6%) serine-type peptidase activity (19.6%) peptidase activity (0.9%)" "IPR001478 (16.9%) IPR004447 (16.9%) IPR005151 (16.9%)" "PDZ domain (16.9%) C-terminal-processing peptidase S41A (16.9%) Tail specific protease (16.9%)" WGSSDHYLGVPVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.2 (100%) pyruvate, water dikinase (100%) "GO:0005524 (50%) GO:0016301 (48.9%) GO:0008986 (1.1%)" "ATP binding (50%) kinase activity (48.9%) pyruvate, water dikinase activity (1.1%)" "IPR002192 (31.3%) IPR051549 (31.3%) IPR013815 (29.3%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (31.3%) Phosphoenolpyruvate Utilizing Enzyme (31.3%) ATP-grasp fold, subdomain 1 (29.3%)" TALVTGAAR root "1.1.1.100 (81.3%) 1.1.1.- (5.6%) 1.1.1.47 (2.8%)" "3-oxoacyl-[acyl-carrier-protein] reductase (81.3%) With NAD(+) or NADP(+) as acceptor (5.6%) glucose 1-dehydrogenase [NAD(P)(+)] (2.8%)" "GO:0006629 (13.2%) GO:0032787 (13.2%) GO:0006633 (9.9%)" "GO:0016020 (0.3%) GO:0005737 (0.2%) GO:0005829 (0%)" "GO:0016491 (15.1%) GO:0016616 (15.1%) GO:0004316 (12.4%)" "lipid metabolic process (13.2%) monocarboxylic acid metabolic process (13.2%) fatty acid biosynthetic process (9.9%)" "membrane (0.3%) cytoplasm (0.2%) cytosol (0%)" "oxidoreductase activity (15.1%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (15.1%) 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (12.4%)" "IPR036291 (23.7%) IPR002347 (23.7%) IPR020904 (19.8%)" "NAD(P)-binding domain superfamily (23.7%) Short-chain dehydrogenase/reductase SDR (23.7%) Short-chain dehydrogenase/reductase, conserved site (19.8%)" YLTATAQHDVLAKPEFTGEDAQLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49%) "GO:0004553 (49%) GO:0016787 (2%)" carbohydrate metabolic process (49%) "hydrolase activity, hydrolyzing O-glycosyl compounds (49%) hydrolase activity (2%)" "IPR000772 (20.5%) IPR006710 (20.5%) IPR050727 (20.5%)" "Ricin B, lectin domain (20.5%) Glycoside hydrolase, family 43 (20.5%) Glycosyl hydrolase 43 family arabinanases (20.5%)" LVTFFGEYLGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR001509 (34.4%) IPR036291 (32.8%) IPR050177 (32.8%)" "NAD-dependent epimerase/dehydratase (34.4%) NAD(P)-binding domain superfamily (32.8%) Bifunctional lipid A modification and metabolic enzymes (32.8%)" APSPYWDPLQWMLEQCHNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR003790 (25.6%) IPR052177 (25.6%) IPR013783 (24.4%)" "Glycosyl hydrolase-like 10 (25.6%) Divisome-localized Glycosyl Hydrolase (25.6%) Immunoglobulin-like fold (24.4%)" TDGVKLENLK root "GO:0005975 (39.5%) GO:0031507 (1.3%) GO:0045892 (1.3%)" "GO:0000791 (1.3%) GO:0031213 (1.3%)" "GO:0004650 (39.5%) GO:0004557 (11.8%) GO:0008270 (1.3%)" "carbohydrate metabolic process (39.5%) heterochromatin formation (1.3%) negative regulation of DNA-templated transcription (1.3%)" "euchromatin (1.3%) RSF complex (1.3%)" "polygalacturonase activity (39.5%) alpha-galactosidase activity (11.8%) zinc ion binding (1.3%)" "IPR000743 (19.6%) IPR006626 (19.6%) IPR051801 (19.6%)" "Glycoside hydrolase, family 28 (19.6%) Parallel beta-helix repeat (19.6%) Glycosyl_Hydrolase_28_Enzymes (19.6%)" FKDAVLAK root "3.2.1.55 (97.6%) 1.14.13.- (2.4%)" "non-reducing end alpha-L-arabinofuranosidase (97.6%) With NADH or NADPH as one donor, and incorporation of one atom of oxygen (2.4%)" "GO:0046373 (43.3%) GO:0006508 (1%) GO:0055085 (1%)" "GO:0005886 (2.1%) GO:0005829 (1%) GO:0016020 (1%)" "GO:0046556 (43.3%) GO:0004497 (1%) GO:0008237 (1%)" "L-arabinose metabolic process (43.3%) proteolysis (1%) transmembrane transport (1%)" "plasma membrane (2.1%) cytosol (1%) membrane (1%)" "alpha-L-arabinofuranosidase activity (43.3%) monooxygenase activity (1%) metallopeptidase activity (1%)" "IPR010720 (13.8%) IPR051563 (13.8%) IPR055235 (13.8%)" "Alpha-L-arabinofuranosidase, C-terminal (13.8%) Glycosyl Hydrolase Family 51 (13.8%) Alpha-L-arabinofuranosidase 1, catalytic domain (13.8%)" EVLDYVDQNPGSLGVLGSNWLNDRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (52%) IPR050811 (48%)" "PBP domain (52%) Phosphate-binding ABC transporter substrate-binding (48%)" HELGQMAVNALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" LTLAADANK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" SGGVQLVLKPGHYDYYSSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.1%) IPR026263 (34.1%) IPR017850 (31.9%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.1%) Alkaline phosphatase, prokaryotic (34.1%) Alkaline-phosphatase-like, core domain superfamily (31.9%)" NDSSLYAFQLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.4%) GO:0005737 (19.4%) "GO:0004177 (20.4%) GO:0008270 (20.4%) GO:0008237 (19.4%)" proteolysis (20.4%) cytoplasm (19.4%) "aminopeptidase activity (20.4%) zinc ion binding (20.4%) metallopeptidase activity (19.4%)" "IPR001948 (51.3%) IPR023358 (48.7%)" "Peptidase M18 (51.3%) Peptidase M18, domain 2 (48.7%)" LTNGHNELLLANR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.2%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.2%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.2%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.2%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.2%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.2%)" "IPR006691 (12.8%) IPR050220 (12.8%) IPR002205 (12.6%)" "DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%) Type II DNA Topoisomerases (12.8%) DNA topoisomerase, type IIA, domain A (12.6%)" YGTYLPFYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) TTYLVNEEGVLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.24 (100%) thioredoxin-dependent peroxiredoxin (100%) "GO:0034599 (25%) GO:0045454 (25%)" GO:0005737 (25%) GO:0008379 (25%) "cellular response to oxidative stress (25%) cell redox homeostasis (25%)" cytoplasm (25%) thioredoxin peroxidase activity (25%) "IPR000866 (21%) IPR013766 (21%) IPR050924 (21%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (21%) Thioredoxin domain (21%) Thiol-specific peroxidase BCP/PrxQ (21%)" DPLGVLPLYLGYDKDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" FAFLTGVTK Pseudomonadati Bacteria Pseudomonadati "GO:0005524 (97.6%) GO:0016787 (2.4%)" "ATP binding (97.6%) hydrolase activity (2.4%)" "IPR018631 (42.8%) IPR012547 (39.2%) IPR027417 (18%)" "AAA-ATPase-like domain (42.8%) PD-(D/E)XK nuclease superfamily 9 (39.2%) P-loop containing nucleoside triphosphate hydrolase (18%)" KDEVGGEVLTTFDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.4.1.21 (100%) S-ribosylhomocysteine lyase (100%) GO:0009372 (33.3%) "GO:0005506 (33.3%) GO:0043768 (33.3%)" quorum sensing (33.3%) "iron ion binding (33.3%) S-ribosylhomocysteine lyase activity (33.3%)" "IPR003815 (33.3%) IPR011249 (33.3%) IPR037005 (33.3%)" "S-ribosylhomocysteinase (LuxS) (33.3%) Metalloenzyme, LuxS/M16 peptidase-like (33.3%) S-ribosylhomocysteinase (LuxS) superfamily (33.3%)" HLEEAGAATVMPLAAPLGTNK Pseudomonadati Bacteria Pseudomonadati 2.8.1.10 (100%) thiazole synthase (100%) "GO:0009229 (30.3%) GO:0009228 (10.1%)" GO:0005737 (29.2%) "GO:1990107 (20.2%) GO:0016783 (10.1%)" "thiamine diphosphate biosynthetic process (30.3%) thiamine biosynthetic process (10.1%)" cytoplasm (29.2%) "thiazole synthase activity (20.2%) sulfurtransferase activity (10.1%)" "IPR008867 (33.8%) IPR033983 (33.8%) IPR013785 (32.5%)" "Thiazole synthase (33.8%) Thiazole synthase ThiG (33.8%) Aldolase-type TIM barrel (32.5%)" EVFTDVDLYDDYVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.9%) IPR008969 (48.1%)" "Family of unknown function DUF5686 (51.9%) Carboxypeptidase-like, regulatory domain superfamily (48.1%)" LNWNPNTTSFEDLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (34%) "GO:0008446 (34%) GO:0070401 (31.9%)" 'de novo' GDP-L-fucose biosynthetic process (34%) "GDP-mannose 4,6-dehydratase activity (34%) NADP+ binding (31.9%)" "IPR006368 (34%) IPR016040 (34%) IPR036291 (31.9%)" "GDP-mannose 4,6-dehydratase (34%) NAD(P)-binding domain (34%) NAD(P)-binding domain superfamily (31.9%)" QLGLGDDELQLLEQLVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025272 (100%) Antitoxin SocA-like, Panacea domain (100%) GTVVDNMGEPVLGASVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (75%) GO:0004180 (25%) cell outer membrane (75%) carboxypeptidase activity (25%) "IPR008969 (16%) IPR000531 (12%) IPR012910 (12%)" "Carboxypeptidase-like, regulatory domain superfamily (16%) TonB-dependent receptor-like, beta-barrel (12%) TonB-dependent receptor, plug domain (12%)" YELYDYTAAAQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0120147 (100%) formylglycine-generating oxidase activity (100%) "IPR005532 (26.3%) IPR051043 (26.3%) IPR016187 (23.7%)" "Sulfatase-modifying factor enzyme-like domain (26.3%) Sulfatase Modifying Factor and Kinase (26.3%) C-type lectin fold (23.7%)" TEQLANYFSEYALLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (20.7%) GO:0044208 (20.7%) GO:0006188 (13.8%)" "GO:0004018 (34.5%) GO:0070626 (8.6%) GO:0016829 (1.7%)" "'de novo' IMP biosynthetic process (20.7%) 'de novo' AMP biosynthetic process (20.7%) IMP biosynthetic process (13.8%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (34.5%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (8.6%) lyase activity (1.7%)" "IPR008948 (12.8%) IPR022761 (12.8%) IPR024083 (12.8%)" "L-Aspartase-like (12.8%) Fumarate lyase, N-terminal (12.8%) Fumarase/histidase, N-terminal (12.8%)" VNPVQGNAYNMFTFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR000600 (20.7%) IPR049874 (20.7%) IPR036388 (19.5%)" "ROK family (20.7%) ROK, conserved site (20.7%) Winged helix-like DNA-binding domain superfamily (19.5%)" QNSSAFPLSHNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.4%) "GO:0000155 (26%) GO:0003700 (24.4%) GO:0043565 (24.4%)" membrane (24.4%) "phosphorelay sensor kinase activity (26%) DNA-binding transcription factor activity (24.4%) sequence-specific DNA binding (24.4%)" "IPR011110 (16.1%) IPR015943 (15.2%) IPR011123 (14.3%)" "Two component regulator propeller (16.1%) WD40/YVTN repeat-like-containing domain superfamily (15.2%) Two component regulator three Y (14.3%)" DVSYLNPEHVGDVYTDRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) TLPGLEAELSQPLQMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (34.2%) IPR004763 (34.2%) IPR027463 (31.5%)" "Acriflavin resistance protein (34.2%) Cation efflux system CusA-like (34.2%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.5%)" LYETVSVNGQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR012944 (34.4%) IPR033985 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) RagB/SusD domain (34.4%) SusD-like, N-terminal (31.3%)" LQVYLAR root "6.1.1.6 (52%) 5.4.99.- (12%) 2.3.3.10 (8%)" "lysine--tRNA ligase (52%) Transferring other groups (12%) hydroxymethylglutaryl-CoA synthase (8%)" "GO:0006430 (7.2%) GO:0000455 (2.7%) GO:0006084 (1.2%)" "GO:0005829 (7.8%) GO:0016020 (4.5%) GO:0005886 (3.5%)" "GO:0005524 (8.9%) GO:0000049 (7.2%) GO:0000287 (7.2%)" "lysyl-tRNA aminoacylation (7.2%) enzyme-directed rRNA pseudouridine synthesis (2.7%) acetyl-CoA metabolic process (1.2%)" "cytosol (7.8%) membrane (4.5%) plasma membrane (3.5%)" "ATP binding (8.9%) tRNA binding (7.2%) magnesium ion binding (7.2%)" "IPR002313 (4.7%) IPR004364 (4.7%) IPR004365 (4.7%)" "Lysine-tRNA ligase, class II (4.7%) Aminoacyl-tRNA synthetase, class II (D/K/N) (4.7%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (4.7%)" MYLPYLEALNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) LDYLLSK root "2.3.1.- (52.1%) 4.2.1.33 (6.7%) 6.3.2.4 (6%)" "Transferring groups other than amino-acyl groups (52.1%) 3-isopropylmalate dehydratase (6.7%) D-alanine--D-alanine ligase (6%)" "GO:0006071 (4.4%) GO:0019432 (4.1%) GO:0046339 (3.6%)" "GO:0005811 (4.4%) GO:0005789 (4%) GO:0005737 (4%)" "GO:0004144 (4.2%) GO:0005085 (2.5%) GO:0005524 (1.5%)" "glycerol metabolic process (4.4%) triglyceride biosynthetic process (4.1%) diacylglycerol metabolic process (3.6%)" "lipid droplet (4.4%) endoplasmic reticulum membrane (4%) cytoplasm (4%)" "diacylglycerol O-acyltransferase activity (4.2%) guanyl-nucleotide exchange factor activity (2.5%) ATP binding (1.5%)" "IPR007130 (5.3%) IPR008937 (3%) IPR023578 (3%)" "Diacylglycerol acyltransferase (5.3%) Ras-like guanine nucleotide exchange factor (3%) Ras guanine nucleotide exchange factor domain superfamily (3%)" VKDLPGVR root "4.1.1.20 (80%) 2.8.1.7 (20%)" "diaminopimelate decarboxylase (80%) cysteine desulfurase (20%)" "GO:0006412 (20.2%) GO:0009089 (0%) GO:0046677 (0%)" "GO:0015935 (20.2%) GO:0009507 (10.2%) GO:0009536 (1.6%)" "GO:0003735 (20.2%) GO:0019843 (19.3%) GO:0000049 (8%)" "translation (20.2%) lysine biosynthetic process via diaminopimelate (0%) response to antibiotic (0%)" "small ribosomal subunit (20.2%) chloroplast (10.2%) plastid (1.6%)" "structural constituent of ribosome (20.2%) rRNA binding (19.3%) tRNA binding (8%)" "IPR005679 (33.1%) IPR006032 (33.1%) IPR012340 (33.1%)" "Ribosomal protein uS12, bacteria (33.1%) Small ribosomal subunit protein uS12 (33.1%) Nucleic acid-binding, OB-fold (33.1%)" TKDFTYNTMLSLSSNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.7%) IPR039426 (15.7%) IPR036942 (14.7%)" "TonB-dependent outer membrane protein, SusC/RagA (15.7%) TonB-dependent receptor-like (15.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.7%)" YVLDGEAR root "2.3.2.27 (60%) 2.5.1.19 (20%) 2.7.13.3 (20%)" "RING-type E3 ubiquitin transferase (60%) 3-phosphoshikimate 1-carboxyvinyltransferase (20%) histidine kinase (20%)" "GO:0016226 (38.3%) GO:0006302 (3.2%) GO:0046394 (2.1%)" "GO:0005576 (5.3%) GO:0016020 (4.3%) GO:0005634 (3.2%)" "GO:0008270 (5.3%) GO:0004842 (3.2%) GO:0031491 (3.2%)" "iron-sulfur cluster assembly (38.3%) double-strand break repair (3.2%) carboxylic acid biosynthetic process (2.1%)" "extracellular region (5.3%) membrane (4.3%) nucleus (3.2%)" "zinc ion binding (5.3%) ubiquitin-protein transferase activity (3.2%) nucleosome binding (3.2%)" "IPR000825 (13.3%) IPR011542 (13.3%) IPR045595 (13.3%)" "SUF system FeS cluster assembly, SufBD core domain (13.3%) SUF system FeS cluster assembly, SufD (13.3%) SUF system FeS cluster assembly, SufBD, N-terminal (13.3%)" LESFPLQLLFDLVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0007234 (20%) GO:0016020 (20%) "GO:0000156 (20%) GO:0016301 (20%) GO:0030295 (20%)" osmosensory signaling via phosphorelay pathway (20%) membrane (20%) "phosphorelay response regulator activity (20%) kinase activity (20%) protein kinase activator activity (20%)" "IPR003594 (12.5%) IPR004358 (12.5%) IPR005467 (12.5%)" "Histidine kinase/HSP90-like ATPase domain (12.5%) Signal transduction histidine kinase-related protein, C-terminal (12.5%) Histidine kinase domain (12.5%)" QAEEQQAYMEAMELAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015031 (16.7%) GO:0015891 (16.7%) GO:0055085 (16.7%)" "GO:0030288 (16.7%) GO:0098797 (16.7%)" GO:0031992 (16.7%) "protein transport (16.7%) siderophore transport (16.7%) transmembrane transport (16.7%)" "outer membrane-bounded periplasmic space (16.7%) plasma membrane protein complex (16.7%)" energy transducer activity (16.7%) "IPR003538 (25%) IPR006260 (25%) IPR037682 (25%)" "Gram-negative bacterial TonB protein (25%) TonB/TolA, C-terminal (25%) TonB, C-terminal (25%)" SGYQWGLGCYVSPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR041246 (20.7%) IPR001599 (18.7%) IPR002890 (18.7%)" "Bacterial alpha-2-macroglobulin MG10 domain (20.7%) Alpha-2-macroglobulin (18.7%) Macroglobulin domain (18.7%)" SWLAELR root "2.7.7.65 (32%) 1.1.3.20 (30.7%) 2.5.1.60 (16%)" "diguanylate cyclase (32%) long-chain-alcohol oxidase (30.7%) protein geranylgeranyltransferase type II (16%)" "GO:0043709 (3.2%) GO:1902201 (3.2%) GO:0035556 (2.1%)" "GO:0005886 (6.1%) GO:0016020 (5.3%) GO:0005737 (3.6%)" "GO:0050660 (3.3%) GO:0046577 (3.2%) GO:0052621 (3.2%)" "cell adhesion involved in single-species biofilm formation (3.2%) negative regulation of bacterial-type flagellum-dependent cell motility (3.2%) intracellular signal transduction (2.1%)" "plasma membrane (6.1%) membrane (5.3%) cytoplasm (3.6%)" "flavin adenine dinucleotide binding (3.3%) long-chain-alcohol oxidase activity (3.2%) diguanylate cyclase activity (3.2%)" "IPR036188 (2.7%) IPR043128 (2.4%) IPR000160 (2.3%)" "FAD/NAD(P)-binding domain superfamily (2.7%) Reverse transcriptase/Diguanylate cyclase domain (2.4%) GGDEF domain (2.3%)" WQNTLFAWFAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.4.-.- (63.6%) 3.4.14.12 (27.3%) 3.4.14.- (9.1%)" "Acting on peptide bonds (peptidases) (63.6%) Xaa-Xaa-Pro tripeptidyl-peptidase (27.3%) Dipeptidyl-peptidases and tripeptidyl-peptidases (9.1%)" GO:0006508 (41.9%) "GO:0004252 (26.1%) GO:0008236 (15.8%) GO:0008239 (15.8%)" proteolysis (41.9%) "serine-type endopeptidase activity (26.1%) serine-type peptidase activity (15.8%) dipeptidyl-peptidase activity (15.8%)" "IPR001375 (29.5%) IPR011042 (28.6%) IPR029058 (28.6%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (29.5%) Six-bladed beta-propeller, TolB-like (28.6%) Alpha/Beta hydrolase fold (28.6%)" QLEGTPQLLLTSLDYSSYTGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0000027 (10%) GO:0009409 (10%) GO:0010467 (10%)" "GO:0005829 (10%) GO:1990904 (10%)" "GO:0000049 (10%) GO:0003924 (10%) GO:0005525 (10%)" "ribosomal large subunit assembly (10%) response to cold (10%) gene expression (10%)" "cytosol (10%) ribonucleoprotein complex (10%)" "tRNA binding (10%) GTPase activity (10%) GTP binding (10%)" "IPR000640 (6.7%) IPR000795 (6.7%) IPR004161 (6.7%)" "Elongation factor EFG, domain V-like (6.7%) Translational (tr)-type GTP-binding domain (6.7%) Translation elongation factor EFTu-like, domain 2 (6.7%)" SLFVSTLQAYYEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.3%) IPR027417 (35%) IPR012547 (26.7%)" "AAA-ATPase-like domain (38.3%) P-loop containing nucleoside triphosphate hydrolase (35%) PD-(D/E)XK nuclease superfamily 9 (26.7%)" LALDYSDGVVEGEEEATQLLFDYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.21 (100%) starch synthase (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR013534 (100%) Starch synthase, catalytic domain (100%) EGVSLSNNNDEGQDWDGCRDLDHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (50%) "GO:0004556 (25%) GO:0043169 (25%)" carbohydrate metabolic process (50%) "alpha-amylase activity (25%) cation binding (25%)" "IPR006047 (50%) IPR006046 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (50%) Alpha amylase (25%) Glycoside hydrolase superfamily (25%)" GLTSGLDENGNAVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) LNVNLDWYKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" FQPQFDVLGPVTLPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) "IPR003961 (23.1%) IPR008757 (23.1%) IPR013783 (19.2%)" "Fibronectin type III (23.1%) Peptidase M6-like, domain (23.1%) Immunoglobulin-like fold (19.2%)" GWDSYLNPFAGHLEDYKDDDQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR041700 (90%) IPR008969 (10%)" "Outer membrane protein beta-barrel domain 3 (90%) Carboxypeptidase-like, regulatory domain superfamily (10%)" SSSTSLPYYGNQTQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GNDLKNDYLTNNLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri WNSFNNYQHNTNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FNTSVNLAPSFLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (14.5%) IPR023996 (14.5%) IPR039426 (14.5%)" "TonB-dependent receptor-like, beta-barrel (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like (14.5%)" QTAYDLASQSLVLLENNGVLPLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009251 (43.3%) GO:0031222 (3.3%) GO:0045493 (3.3%)" "GO:0008422 (43.3%) GO:0009044 (3.3%) GO:0046556 (3.3%)" "glucan catabolic process (43.3%) arabinan catabolic process (3.3%) xylan catabolic process (3.3%)" "beta-glucosidase activity (43.3%) xylan 1,4-beta-xylosidase activity (3.3%) alpha-L-arabinofuranosidase activity (3.3%)" "IPR002772 (14.1%) IPR001764 (13.1%) IPR026891 (13.1%)" "Glycoside hydrolase family 3 C-terminal domain (14.1%) Glycoside hydrolase, family 3, N-terminal (13.1%) Fibronectin type III-like domain (13.1%)" GAVGQAVQNMNLMFGLDQTAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.38 (100%) N-acetyl-gamma-glutamyl-phosphate reductase (100%) GO:0006526 (20%) GO:0005737 (20%) "GO:0003942 (20%) GO:0051287 (20%) GO:0070401 (20%)" L-arginine biosynthetic process (20%) cytoplasm (20%) "N-acetyl-gamma-glutamyl-phosphate reductase activity (20%) NAD binding (20%) NADP+ binding (20%)" "IPR000534 (20.2%) IPR000706 (20.2%) IPR023013 (20.2%)" "Semialdehyde dehydrogenase, NAD-binding (20.2%) N-acetyl-gamma-glutamyl-phosphate reductase, type 1 (20.2%) N-acetyl-gamma-glutamyl-phosphate reductase, active site (20.2%)" KYGYLFK root "3.1.1.11 (87.5%) 2.1.1.56 (12.5%)" "pectinesterase (87.5%) mRNA (guanine-N(7))-methyltransferase (12.5%)" "GO:0042545 (5.2%) GO:0045490 (4.5%) GO:0005975 (0.6%)" "GO:0009279 (20.8%) GO:0016020 (4.5%) GO:0005739 (3.9%)" "GO:0052689 (14.3%) GO:0004557 (9.1%) GO:0030599 (5.2%)" "cell wall modification (5.2%) pectin catabolic process (4.5%) carbohydrate metabolic process (0.6%)" "cell outer membrane (20.8%) membrane (4.5%) mitochondrion (3.9%)" "carboxylic ester hydrolase activity (14.3%) alpha-galactosidase activity (9.1%) pectinesterase activity (5.2%)" "IPR011050 (12.1%) IPR012334 (12.1%) IPR032812 (11.7%)" "Pectin lyase fold/virulence factor (12.1%) Pectin lyase fold (12.1%) SbsA, Ig-like domain (11.7%)" LYLPALENLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (1.9%) GO:0005829 (32.1%) "GO:0003677 (34%) GO:0003700 (32.1%)" regulation of DNA-templated transcription (1.9%) cytosol (32.1%) "DNA binding (34%) DNA-binding transcription factor activity (32.1%)" "IPR012318 (15.1%) IPR000595 (14.3%) IPR014710 (14.3%)" "Crp-type HTH domain (15.1%) Cyclic nucleotide-binding domain (14.3%) RmlC-like jelly roll fold (14.3%)" LHMLFETAKGEEGLHEALDELCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.4.1.13 (97.4%) 1.4.-.- (2.6%)" "glutamate synthase (NADPH) (97.4%) Acting on the CH-NH2 group of donors (2.6%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.4%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.4%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" SVNQAPSLGNLPANLSNQMTGLLTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) TGNQYQVTGSYYLPVDAFSYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0004713 (25%) GO:0005524 (25%) GO:0042802 (25%)" plasma membrane (25%) "protein tyrosine kinase activity (25%) ATP binding (25%) identical protein binding (25%)" "IPR003856 (16.7%) IPR005702 (16.7%) IPR025669 (16.7%)" "Polysaccharide chain length determinant, N-terminal domain (16.7%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.7%) AAA domain (16.7%)" YTWLFGELKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (42.9%) "GO:0015926 (42.9%) GO:0031218 (14.3%)" pectin catabolic process (42.9%) "glucosidase activity (42.9%) arabinogalactan endo-1,4-beta-galactosidase activity (14.3%)" "IPR011683 (50%) IPR017853 (50%)" "Glycosyl hydrolase family 53 (50%) Glycoside hydrolase superfamily (50%)" MSGVQVMSSGVPGGAMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (15.8%) GO:0009279 (84.2%) iron ion transport (15.8%) cell outer membrane (84.2%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" SLDDLVDEYQLLDNLHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR004680 (25.2%) IPR006037 (25.2%) IPR051679 (25.2%)" "Citrate transporter-like domain (25.2%) Regulator of K+ conductance, C-terminal (25.2%) Divalent Anion Sodium Symporter-Related Transporters (25.2%)" KTNFFSMVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" HWQDLTGAEYPFYVTDETTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.4%) GO:0006096 (12.4%) GO:0019563 (12.4%)" "GO:0016020 (12.8%) GO:0005829 (12.4%)" "GO:0004807 (12.4%) GO:0016853 (0.4%)" "gluconeogenesis (12.4%) glycolytic process (12.4%) glycerol catabolic process (12.4%)" "membrane (12.8%) cytosol (12.4%)" "triose-phosphate isomerase activity (12.4%) isomerase activity (0.4%)" "IPR000652 (17%) IPR009908 (17%) IPR020861 (17%)" "Triosephosphate isomerase (17%) Methylamine utilisation protein, MauE (17%) Triosephosphate isomerase, active site (17%)" SYFATGFPLGTCLASTWNTDLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (13.1%) IPR050288 (13.1%) IPR002772 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (13.1%) Cellulose-degrading glycosyl hydrolase 3 (13.1%) Glycoside hydrolase family 3 C-terminal domain (12.5%)" TNLLGLATTSLNAGLELGTGRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) ALGVSTTALSDLLHGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003677 (100%) DNA binding (100%) "IPR001387 (52.9%) IPR010982 (47.1%)" "Cro/C1-type, helix-turn-helix domain (52.9%) Lambda repressor-like, DNA-binding domain superfamily (47.1%)" YNCFTLPENELLLGTDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TLGDEKYVVVVNPGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (25.9%) IPR013780 (24.7%) IPR017853 (24.7%)" "Glycosyl hydrolase family 13, catalytic domain (25.9%) Glycosyl hydrolase, all-beta (24.7%) Glycoside hydrolase superfamily (24.7%)" LVFMGTPEFAVESLKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.1.2.9 (100%) methionyl-tRNA formyltransferase (100%) GO:0005829 (50%) GO:0004479 (50%) cytosol (50%) methionyl-tRNA formyltransferase activity (50%) "IPR002376 (13.7%) IPR041711 (13.7%) IPR005793 (12.9%)" "Formyl transferase, N-terminal (13.7%) Methionyl-tRNA formyltransferase, N-terminal domain (13.7%) Formyl transferase, C-terminal (12.9%)" AVFDEYTDGEGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.9%) GO:0006811 (3.1%)" GO:0009279 (50%) "iron ion transport (46.9%) monoatomic ion transport (3.1%)" cell outer membrane (50%) "IPR000531 (25.6%) IPR039426 (25.6%) IPR012910 (24.8%)" "TonB-dependent receptor-like, beta-barrel (25.6%) TonB-dependent receptor-like (25.6%) TonB-dependent receptor, plug domain (24.8%)" DLVDQLFNATVANW Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0043165 (50%) GO:0019867 (50%) Gram-negative-bacterium-type cell outer membrane assembly (50%) outer membrane (50%) IPR007485 (100%) LPS-assembly lipoprotein LptE (100%) ARAEGLDLECK Bacteria Bacteria 2.7.8.- (100%) Transferases for other substituted phosphate groups (100%) GO:0008654 (33.3%) GO:0016020 (33.3%) GO:0016780 (33.3%) phospholipid biosynthetic process (33.3%) membrane (33.3%) phosphotransferase activity, for other substituted phosphate groups (33.3%) "IPR000462 (33.3%) IPR048254 (33.3%) IPR043130 (32.1%)" "CDP-alcohol phosphatidyltransferase (33.3%) CDP-alcohol phosphatidyltransferase, conserved site (33.3%) CDP-alcohol phosphatidyltransferase, transmembrane domain (32.1%)" EDGTVDEAWMNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (20.4%) GO:0006080 (18.4%) GO:0030245 (10.2%)" "GO:0005576 (10.2%) GO:0009986 (10.2%)" "GO:0016985 (18.4%) GO:0008422 (10.2%) GO:0004553 (2%)" "polysaccharide catabolic process (20.4%) substituted mannan metabolic process (18.4%) cellulose catabolic process (10.2%)" "extracellular region (10.2%) cell surface (10.2%)" "mannan endo-1,4-beta-mannosidase activity (18.4%) beta-glucosidase activity (10.2%) hydrolase activity, hydrolyzing O-glycosyl compounds (2%)" "IPR001547 (26.3%) IPR017853 (26.3%) IPR022790 (22.8%)" "Glycoside hydrolase, family 5 (26.3%) Glycoside hydrolase superfamily (26.3%) Glycosyl hydrolase family 26 domain (22.8%)" LQYAGGETDGLSVDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR003284 (14.3%) IPR006530 (14.3%) IPR022045 (14.3%)" "Salmonella virulence plasmid 65kDa B protein (14.3%) YD repeat (14.3%) Insecticide toxin TcdB middle/N-terminal (14.3%)" FLGVELTGPLDVSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004386 (100%) helicase activity (100%) "IPR007936 (39.4%) IPR024450 (39.4%) IPR014907 (21.2%)" "Virulence-associated protein E-like domain (39.4%) Domain of unknown function DUF3874 (39.4%) BT4734-like, N-terminal (21.2%)" NVPLVVDSTVLPFTQFSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019346 (20.4%) GO:0005737 (20.4%) "GO:0016846 (20.4%) GO:0030170 (20.4%) GO:0016740 (12%)" transsulfuration (20.4%) cytoplasm (20.4%) "carbon-sulfur lyase activity (20.4%) pyridoxal phosphate binding (20.4%) transferase activity (12%)" "IPR000277 (25.3%) IPR015421 (25.3%) IPR015424 (25.3%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (25.3%) Pyridoxal phosphate-dependent transferase, major domain (25.3%) Pyridoxal phosphate-dependent transferase (25.3%)" TDRGDALFPNALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR045724 (100%) Protein of unknown function DUF6078 (100%) GSHFNNLETPTGEVDEEGNPLTER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" ARNEVEALMWHCYSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0009055 (33.3%) GO:0020037 (33.3%) GO:0004130 (29.3%)" "electron transfer activity (33.3%) heme binding (33.3%) cytochrome-c peroxidase activity (29.3%)" "IPR010538 (36.7%) IPR036909 (31.6%) IPR051395 (27.8%)" "Di-haem oxidoreductase, putative peroxidase (36.7%) Cytochrome c-like domain superfamily (31.6%) Cytochrome c-dependent Peroxidase and MauG (27.8%)" AEENLLSYFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (36%) GO:0009279 (64%) iron ion transport (36%) cell outer membrane (64%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DVYPMSR root 3.1.26.4 (100%) ribonuclease H (100%) "GO:0006508 (4%) GO:0006915 (4%)" GO:0009279 (80%) "GO:0004197 (4%) GO:0004672 (4%) GO:0005524 (4%)" "proteolysis (4%) apoptotic process (4%)" cell outer membrane (80%) "cysteine-type endopeptidase activity (4%) protein kinase activity (4%) ATP binding (4%)" "IPR023996 (14%) IPR039426 (14%) IPR012910 (12.6%)" "TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent receptor-like (14%) TonB-dependent receptor, plug domain (12.6%)" SQYELEAFGDSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0016787 (50%) membrane (50%) hydrolase activity (50%) "IPR023214 (33.3%) IPR036412 (33.3%) IPR050582 (33.3%)" "HAD superfamily (33.3%) HAD-like superfamily (33.3%) HAD-like hydrolase superfamily, SerB (33.3%)" LPNTQGYR Pseudomonadati Bacteria Pseudomonadati 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.7%) GO:0046373 (33%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.7%) L-arabinose metabolic process (33%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (28.3%) IPR017853 (27.9%) IPR013780 (27.3%)" "Alpha-L-arabinofuranosidase, C-terminal (28.3%) Glycoside hydrolase superfamily (27.9%) Glycosyl hydrolase, all-beta (27.3%)" LDAAVAEDGTVADVDLTRPLLSFGSDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) MDLSQAEAVADLLASTNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.-.- (100%) Acting on acid anhydrides (100%) "GO:0002098 (14.4%) GO:0030488 (14.4%)" GO:0005829 (14.4%) "GO:0005525 (14.4%) GO:0046872 (14.4%) GO:0003924 (13.7%)" "tRNA wobble uridine modification (14.4%) tRNA methylation (14.4%)" cytosol (14.4%) "GTP binding (14.4%) metal ion binding (14.4%) GTPase activity (13.7%)" "IPR005225 (11.5%) IPR006073 (11.5%) IPR025867 (11.5%)" "Small GTP-binding domain (11.5%) GTP binding domain (11.5%) MnmE, helical domain (11.5%)" HNAQYAPLDVETFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR018873 (100%) KilA-N, DNA-binding domain (100%) VALNEGLR root "3.6.5.3 (98.8%) 2.4.-.- (1.3%)" "protein-synthesizing GTPase (98.8%) Glycosyltransferases (1.3%)" "GO:0001916 (0.2%) GO:0002476 (0.2%) GO:0002486 (0.2%)" "GO:0005829 (13.5%) GO:0032045 (12.1%) GO:0016020 (0.5%)" "GO:0003746 (13.7%) GO:0005525 (13.7%) GO:0003924 (13.2%)" "positive regulation of T cell mediated cytotoxicity (0.2%) antigen processing and presentation of endogenous peptide antigen via MHC class Ib (0.2%) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (0.2%)" "cytosol (13.5%) guanyl-nucleotide exchange factor complex (12.1%) membrane (0.5%)" "translation elongation factor activity (13.7%) GTP binding (13.7%) GTPase activity (13.2%)" "IPR004160 (8.1%) IPR009000 (8.1%) IPR009001 (8.1%)" "Translation elongation factor EFTu/EF1A, C-terminal (8.1%) Translation protein, beta-barrel domain superfamily (8.1%) Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal (8.1%)" PAYNSPSVPLTWPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" PFEERPGGFFHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (24.2%) GO:0005886 (25.5%) "GO:0042910 (25.5%) GO:0015562 (24.8%)" response to toxic substance (24.2%) plasma membrane (25.5%) "xenobiotic transmembrane transporter activity (25.5%) efflux transmembrane transporter activity (24.8%)" "IPR001036 (33.9%) IPR004764 (33%) IPR027463 (33%)" "Acriflavin resistance protein (33.9%) Multidrug resistance protein MdtF-like (33%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33%)" VAFSLSGVGMEQLELHAPQVLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) "GO:0003824 (35.7%) GO:0016787 (14.3%)" carbohydrate metabolic process (50%) "catalytic activity (35.7%) hydrolase activity (14.3%)" "IPR004300 (34%) IPR052046 (34%) IPR011330 (32%)" "Glycoside hydrolase family 57, N-terminal domain (34%) Glycosyl hydrolase family 57 (34%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32%)" YHPHGDFSVYGALVR Pseudomonadati Bacteria Pseudomonadati 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.7%) GO:0006261 (11.8%)" "GO:0005737 (12.7%) GO:0009330 (12.7%) GO:0005694 (11.8%)" "GO:0003677 (12.7%) GO:0005524 (12.7%) GO:0034335 (11.8%)" "DNA topological change (12.7%) DNA-templated DNA replication (11.8%)" "cytoplasm (12.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.7%) chromosome (11.8%)" "DNA binding (12.7%) ATP binding (12.7%) DNA negative supercoiling activity (11.8%)" "IPR002205 (12.8%) IPR013758 (12.8%) IPR013760 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA topoisomerase, type IIA, domain A, alpha-beta (12.8%) DNA topoisomerase, type IIA-like domain superfamily (12.8%)" YLSSYGLQTMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.14.- (100%) Dipeptidyl-peptidases and tripeptidyl-peptidases (100%) "GO:0043171 (25.2%) GO:0006508 (24.5%)" "GO:0008239 (25.2%) GO:0070009 (25.2%)" "peptide catabolic process (25.2%) proteolysis (24.5%)" "dipeptidyl-peptidase activity (25.2%) serine-type aminopeptidase activity (25.2%)" "IPR019500 (34.6%) IPR009003 (32.7%) IPR043504 (32.7%)" "Peptidase S46 (34.6%) Peptidase S1, PA clan (32.7%) Peptidase S1, PA clan, chymotrypsin-like fold (32.7%)" DLGTTVFPNAELK Bacteria Bacteria "2.7.4.25 (96.9%) 6.3.2.1 (3.1%)" "(d)CMP kinase (96.9%) pantoate--beta-alanine ligase (AMP-forming) (3.1%)" "GO:0015949 (17.3%) GO:0006220 (17%) GO:0015940 (0.6%)" "GO:0005829 (17.3%) GO:0005737 (1%) GO:0016020 (1%)" "GO:0005524 (18.6%) GO:0036431 (18.6%) GO:0036430 (8%)" "nucleobase-containing small molecule interconversion (17.3%) pyrimidine nucleotide metabolic process (17%) pantothenate biosynthetic process (0.6%)" "cytosol (17.3%) cytoplasm (1%) membrane (1%)" "ATP binding (18.6%) dCMP kinase activity (18.6%) CMP kinase activity (8%)" "IPR003136 (31.9%) IPR011994 (31.9%) IPR027417 (31.9%)" "Cytidylate kinase (31.9%) Cytidylate kinase domain (31.9%) P-loop containing nucleoside triphosphate hydrolase (31.9%)" YGKGETHLTDLTVNGTPVTSFTTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) QYLSDYYVENASFLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0009279 (100%) cell outer membrane (100%) "IPR039426 (11.6%) IPR000531 (11.4%) IPR012910 (11.4%)" "TonB-dependent receptor-like (11.6%) TonB-dependent receptor-like, beta-barrel (11.4%) TonB-dependent receptor, plug domain (11.4%)" LFQMVGNDEATAQKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" ATDPLTSLYGAFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.33 (100%) pantothenate kinase (100%) GO:0015937 (25%) GO:0005829 (25%) "GO:0004594 (25%) GO:0005524 (25%)" coenzyme A biosynthetic process (25%) cytosol (25%) "pantothenate kinase activity (25%) ATP binding (25%)" "IPR004567 (50%) IPR043129 (50%)" "Type II pantothenate kinase (50%) ATPase, nucleotide binding domain (50%)" WADFFSVSGAWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" GGGLVTGVTETSDGLTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (68.4%) IPR008160 (31.6%)" "Domain of unknown function DUF4988 (68.4%) Collagen triple helix repeat (31.6%)" LYYSLDYAGKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030246 (50%) GO:0016798 (47.1%) GO:0016787 (2.9%)" "carbohydrate binding (50%) hydrolase activity, acting on glycosyl bonds (47.1%) hydrolase activity (2.9%)" "IPR029486 (13%) IPR014718 (12.7%) IPR019563 (12.7%)" "Glycosyl-hydrolase 97, N-terminal domain (13%) Glycoside hydrolase-type carbohydrate-binding (12.7%) Glycosyl-hydrolase 97, catalytic domain (12.7%)" LMNADQGQFSLEDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006974 (52.6%) GO:0016020 (47.4%) DNA damage response (52.6%) membrane (47.4%) "IPR007497 (33.9%) IPR052022 (33.9%) IPR016907 (32.2%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.9%) 26 kDa periplasmic antigen-related (33.9%) Uncharacterised conserved protein UCP029033, periplasmic protein (32.2%)" KSYAFYSLVLADVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (24.9%) "GO:0005737 (24.9%) GO:0015935 (24.9%) GO:0005840 (0.4%)" GO:0003735 (24.9%) translation (24.9%) "cytoplasm (24.9%) small ribosomal subunit (24.9%) ribosome (0.4%)" structural constituent of ribosome (24.9%) "IPR000307 (50%) IPR023803 (50%)" "Small ribosomal subunit protein bS16 (50%) Small ribosomal subunit protein bS16 domain superfamily (50%)" RMEVYAEVLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) GO:0002949 (42.9%) GO:0005829 (42.9%) "GO:0016746 (10.7%) GO:0016740 (3.6%)" tRNA threonylcarbamoyladenosine modification (42.9%) cytosol (42.9%) "acyltransferase activity (10.7%) transferase activity (3.6%)" "IPR000905 (33.3%) IPR022496 (33.3%) IPR043129 (33.3%)" "Gcp-like domain (33.3%) tRNA threonylcarbamoyl adenosine modification protein TsaB (33.3%) ATPase, nucleotide binding domain (33.3%)" STEDGKEVEVDPNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.5%) IPR004154 (11.5%) IPR004499 (11.5%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.5%) Anticodon-binding (11.5%) Proline-tRNA ligase, class IIa, archaeal-type (11.5%)" VDTYLSK root "1.4.3.16 (63.4%) 2.1.1.72 (5.4%) 1.3.1.- (3.2%)" "L-aspartate oxidase (63.4%) site-specific DNA-methyltransferase (adenine-specific) (5.4%) With NAD(+) or NADP(+) as acceptor (3.2%)" "GO:0034628 (9.1%) GO:0051301 (1.8%) GO:0000272 (1.5%)" "GO:0016020 (11.7%) GO:0005737 (8.6%) GO:0005829 (1.3%)" "GO:0008734 (9.1%) GO:0016787 (3%) GO:0046872 (2.9%)" "'de novo' NAD+ biosynthetic process from L-aspartate (9.1%) cell division (1.8%) polysaccharide catabolic process (1.5%)" "membrane (11.7%) cytoplasm (8.6%) cytosol (1.3%)" "L-aspartate oxidase activity (9.1%) hydrolase activity (3%) metal ion binding (2.9%)" "IPR027628 (7.2%) IPR036188 (5.8%) IPR003953 (5.7%)" "Conjugal transfer/type IV secretion protein DotA/TraY (7.2%) FAD/NAD(P)-binding domain superfamily (5.8%) FAD-dependent oxidoreductase 2, FAD-binding domain (5.7%)" NLLVTGSNGSFSLPESTFDQTLESGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) QSGCGELLSNCLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001296 (34.4%) IPR028098 (34.4%) IPR050194 (31.3%)" "Glycosyl transferase, family 1 (34.4%) Glycosyltransferase subfamily 4-like, N-terminal domain (34.4%) Glycosyltransferase group 1 (31.3%)" KQGDYHTWVTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (36.7%) IPR012944 (36.7%) IPR033985 (26.7%)" "Tetratricopeptide-like helical domain superfamily (36.7%) RagB/SusD domain (36.7%) SusD-like, N-terminal (26.7%)" SDLTFENDHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.1%) GO:0006221 (13.6%) GO:0006526 (13.6%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (13.6%) L-arginine biosynthetic process (13.6%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005480 (10.9%) IPR005479 (10.5%) IPR011761 (10.5%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.9%) Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%)" VSWVDDK root "1.4.1.4 (75.7%) 2.7.11.1 (8.1%) 2.1.1.- (5.4%)" "glutamate dehydrogenase (NADP(+)) (75.7%) non-specific serine/threonine protein kinase (8.1%) Methyltransferases (5.4%)" "GO:0006537 (24%) GO:0035556 (0.3%) GO:0000724 (0.2%)" "GO:0005829 (24.3%) GO:0005737 (0.6%) GO:0016020 (0.6%)" "GO:0004354 (24%) GO:0000166 (22%) GO:0004352 (1.4%)" "glutamate biosynthetic process (24%) intracellular signal transduction (0.3%) double-strand break repair via homologous recombination (0.2%)" "cytosol (24.3%) cytoplasm (0.6%) membrane (0.6%)" "glutamate dehydrogenase (NADP+) activity (24%) nucleotide binding (22%) glutamate dehydrogenase (NAD+) activity (1.4%)" "IPR006097 (11%) IPR046346 (11%) IPR050724 (11%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (11%) Glutamate/Leucine/Phenylalanine/Valine dehydrogenases (11%)" EVAESGNNFFSFTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.7%) IPR013486 (12.7%) IPR013693 (12.7%)" "Glycosyltransferase 2-like (12.7%) Sporulation stage II protein D, amidase enhancer LytB (12.7%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.7%)" AQALADYLAQPDREEYQFAALYDLR Pseudomonadati Bacteria Pseudomonadati GO:0030435 (100%) sporulation resulting in formation of a cellular spore (100%) "IPR001173 (12.5%) IPR013486 (12.5%) IPR013693 (12.5%)" "Glycosyltransferase 2-like (12.5%) Sporulation stage II protein D, amidase enhancer LytB (12.5%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (12.5%)" LHDYGASWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR011630 (100%) Nucleotide modification associated domain 1 (100%) LPDFYYNLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005615 (62.5%) GO:0005737 (12.5%) GO:0005886 (12.5%)" "extracellular space (62.5%) cytoplasm (12.5%) plasma membrane (12.5%)" "IPR001611 (17.7%) IPR032675 (15.9%) IPR027899 (15%)" "Leucine-rich repeat (17.7%) Leucine-rich repeat domain superfamily (15.9%) Domain of unknown function DUF4458 (15%)" SDLLADFR root "2.3.1.12 (28.6%) 2.7.11.1 (14.3%) 2.7.13.3 (14.3%)" "dihydrolipoyllysine-residue acetyltransferase (28.6%) non-specific serine/threonine protein kinase (14.3%) histidine kinase (14.3%)" "GO:0000160 (6.6%) GO:0006086 (3.3%) GO:0000245 (1.6%)" "GO:0005737 (14.8%) GO:0016020 (6.6%) GO:0045254 (3.3%)" "GO:0004672 (6.6%) GO:0008081 (6.6%) GO:0004742 (3.3%)" "phosphorelay signal transduction system (6.6%) pyruvate decarboxylation to acetyl-CoA (3.3%) spliceosomal complex assembly (1.6%)" "cytoplasm (14.8%) membrane (6.6%) pyruvate dehydrogenase complex (3.3%)" "protein kinase activity (6.6%) phosphoric diester hydrolase activity (6.6%) dihydrolipoyllysine-residue acetyltransferase activity (3.3%)" "IPR024480 (11.5%) IPR036737 (11.5%) IPR006076 (5.2%)" "Domain of unknown function DUF3868 (11.5%) OmpA-like domain superfamily (11.5%) FAD dependent oxidoreductase (5.2%)" YYDLALR root "2.3.2.31 (30.8%) 3.4.16.4 (15.4%) 2.7.13.3 (11.5%)" "RBR-type E3 ubiquitin transferase (30.8%) serine-type D-Ala-D-Ala carboxypeptidase (15.4%) histidine kinase (11.5%)" "GO:0015979 (1.7%) GO:0016567 (1.7%) GO:0008360 (1.3%)" "GO:0016020 (14.2%) GO:0005737 (2.7%) GO:0005886 (1.9%)" "GO:0005524 (15.7%) GO:0005525 (14%) GO:0005509 (2.7%)" "photosynthesis (1.7%) protein ubiquitination (1.7%) regulation of cell shape (1.3%)" "membrane (14.2%) cytoplasm (2.7%) plasma membrane (1.9%)" "ATP binding (15.7%) GTP binding (14%) calcium ion binding (2.7%)" "IPR027417 (8%) IPR032533 (7.8%) IPR049208 (7.8%)" "P-loop containing nucleoside triphosphate hydrolase (8%) Domain of unknown function DUF4954 (7.8%) Domain of unknown function DUF6819 (7.8%)" QEAPAYDFSNLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.9%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.9%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.7%) IPR003593 (10.7%) IPR004665 (10.7%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.7%) AAA+ ATPase domain (10.7%) Transcription termination factor Rho (10.7%)" YLFQFTFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.5%) IPR012910 (13.5%) IPR023996 (13.5%)" "Carboxypeptidase-like, regulatory domain superfamily (13.5%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%)" QPVSGLLATHDLELSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006298 (17%) "GO:0005829 (16.6%) GO:0016020 (15.8%)" "GO:0005524 (17%) GO:0030983 (17%) GO:0140664 (16.6%)" mismatch repair (17%) "cytosol (16.6%) membrane (15.8%)" "ATP binding (17%) mismatched DNA binding (17%) ATP-dependent DNA damage sensor activity (16.6%)" "IPR000432 (34.2%) IPR045076 (33.3%) IPR027417 (32.5%)" "DNA mismatch repair protein MutS, C-terminal (34.2%) DNA mismatch repair MutS (33.3%) P-loop containing nucleoside triphosphate hydrolase (32.5%)" SDLSNHDYVQYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (50.8%) IPR008969 (49.2%)" "Family of unknown function DUF5686 (50.8%) Carboxypeptidase-like, regulatory domain superfamily (49.2%)" TKFNGAWGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR006665 (26.8%) IPR050330 (26.8%) IPR011250 (23.2%)" "OmpA-like domain (26.8%) Bacterial Outer Membrane Structural/Functional (26.8%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (23.2%)" VTDVPWAFLFVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.5.1.145 (79.3%) 2.4.99.- (20.7%)" "phosphatidylglycerol--prolipoprotein diacylglyceryl transferase (79.3%) Transferring other glycosyl groups (20.7%)" GO:0042158 (33.3%) GO:0005886 (33.3%) GO:0008961 (33.3%) lipoprotein biosynthetic process (33.3%) plasma membrane (33.3%) phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity (33.3%) IPR001640 (100%) Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase Lgt (100%) ELYYADFSLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" RFFQMLEETLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) QHGGLTGGFSMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025665 (67.7%) IPR011250 (32.3%)" "Outer membrane protein, beta-barrel domain 2 (67.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (32.3%)" ALSGGVETLLTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" GLNEDVVR root "2.7.9.1 (52.6%) 3.5.1.88 (26.3%) 4.4.1.11 (5.3%)" "pyruvate, phosphate dikinase (52.6%) peptide deformylase (26.3%) methionine gamma-lyase (5.3%)" "GO:0016226 (92.3%) GO:0006412 (0.5%) GO:0043686 (0.5%)" "GO:1990229 (0.3%) GO:0005737 (0.2%) GO:0009507 (0.2%)" "GO:0046872 (1.4%) GO:0005524 (1%) GO:0016301 (0.9%)" "iron-sulfur cluster assembly (92.3%) translation (0.5%) obsolete co-translational protein modification (0.5%)" "iron-sulfur cluster assembly complex (0.3%) cytoplasm (0.2%) chloroplast (0.2%)" "metal ion binding (1.4%) ATP binding (1%) kinase activity (0.9%)" "IPR055346 (19.5%) IPR000825 (19.5%) IPR037284 (19.5%)" "SUF system FeS cluster assembly, SufBD (19.5%) SUF system FeS cluster assembly, SufBD core domain (19.5%) SUF system FeS cluster assembly, SufBD superfamily (19.5%)" SFGEAHQLETLVDETGNVLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.7%) IPR002933 (33.7%) IPR011650 (32.5%)" "Peptidase M20C, Xaa-His dipeptidase (33.7%) Peptidase M20 (33.7%) Peptidase M20, dimerisation domain (32.5%)" NPVSSLVK root "GO:0005886 (38.5%) GO:0005634 (7.7%) GO:0016020 (7.7%)" "GO:0004930 (15.4%) GO:0016627 (15.4%) GO:0050660 (15.4%)" "plasma membrane (38.5%) nucleus (7.7%) membrane (7.7%)" "G protein-coupled receptor activity (15.4%) oxidoreductase activity, acting on the CH-CH group of donors (15.4%) flavin adenine dinucleotide binding (15.4%)" "IPR021457 (38.9%) IPR000276 (5.6%) IPR006091 (5.6%)" "Protein of unknown function DUF3108 (38.9%) G protein-coupled receptor, rhodopsin-like (5.6%) Acyl-CoA oxidase/dehydrogenase, middle domain (5.6%)" RDEYLSMEVYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.3%) GO:0016020 (1%)" "GO:0008658 (11.3%) GO:0008955 (11.3%) GO:0004180 (10.3%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.3%) membrane (1%)" "penicillin binding (11.3%) peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.3%)" "IPR001460 (17.4%) IPR050396 (17.4%) IPR001264 (16.9%)" "Penicillin-binding protein, transpeptidase (17.4%) Glycosyltransferase 51/Transpeptidase (17.4%) Glycosyl transferase, family 51 (16.9%)" VYAEFAENYMGVPVLQGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.1%) IPR004154 (11.1%) IPR004499 (11.1%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Anticodon-binding (11.1%) Proline-tRNA ligase, class IIa, archaeal-type (11.1%)" DFSWSANVNFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LVFVRDENEAYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0016020 (15.4%) GO:0005886 (4.6%)" "GO:0048038 (20%) GO:0051539 (20%) GO:0016651 (15.4%)" "membrane (15.4%) plasma membrane (4.6%)" "quinone binding (20%) 4 iron, 4 sulfur cluster binding (20%) oxidoreductase activity, acting on NAD(P)H (15.4%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" QYSGDYLMK Pseudomonadati Bacteria Pseudomonadati 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR031705 (13.1%) IPR013780 (12.8%) IPR002252 (12.5%)" "Glycosyl hydrolase family 36, C-terminal (13.1%) Glycosyl hydrolase, all-beta (12.8%) Glycoside hydrolase family 36 (12.5%)" SYWTAEER Bacteria Bacteria "GO:0005840 (50%) GO:0016020 (50%)" "ribosome (50%) membrane (50%)" IPR015032 (100%) Thoeris protein ThsB, TIR-like domain (100%) MCSYGDFVALSDVCDEATALLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.2.3 (100%) phosphoribosylaminoimidazolecarboxamide formyltransferase (100%) GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (26%) IPR016193 (24.7%) IPR024050 (24.7%)" "Bifunctional purine biosynthesis protein PurH-like (26%) Cytidine deaminase-like (24.7%) AICAR transformylase, insert domain superfamily (24.7%)" NTYVLPLLLKDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" MFENLSDRLER Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20%) "GO:0048500 (19.5%) GO:0005786 (0.5%)" "GO:0003924 (20%) GO:0005525 (20%) GO:0008312 (19.9%)" SRP-dependent cotranslational protein targeting to membrane (20%) "signal recognition particle (19.5%) signal recognition particle, endoplasmic reticulum targeting (0.5%)" "GTPase activity (20%) GTP binding (20%) 7S RNA binding (19.9%)" "IPR013822 (11.2%) IPR022941 (11.2%) IPR042101 (11.2%)" "Signal recognition particle SRP54, helical bundle (11.2%) Signal recognition particle, SRP54 subunit (11.2%) Signal recognition particle SRP54, N-terminal domain superfamily (11.2%)" ASLPNTTFPGLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (50%) GO:0009279 (50%) iron ion transport (50%) cell outer membrane (50%) "IPR000531 (25%) IPR012910 (25%) IPR036942 (25%)" "TonB-dependent receptor-like, beta-barrel (25%) TonB-dependent receptor, plug domain (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%)" HFATEDSFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071470 (33.3%) GO:0005886 (33.3%) GO:0008381 (33.3%) cellular response to osmotic stress (33.3%) plasma membrane (33.3%) mechanosensitive monoatomic ion channel activity (33.3%) "IPR006685 (25.8%) IPR030192 (25.8%) IPR010920 (24.2%)" "Mechanosensitive ion channel MscS (25.8%) Miniconductance mechanosensitive channel YbdG (25.8%) LSM domain superfamily (24.2%)" QVQPNAYLSSSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033985 (55.6%) IPR011990 (44.4%)" "SusD-like, N-terminal (55.6%) Tetratricopeptide-like helical domain superfamily (44.4%)" TDLTRDEFLK Pseudomonadati Bacteria Pseudomonadati 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20%) GO:0005829 (20%) "GO:0004832 (20%) GO:0005524 (20%) GO:0002161 (19.8%)" valyl-tRNA aminoacylation (20%) cytosol (20%) "valine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.8%)" "IPR002300 (9.2%) IPR002303 (9.2%) IPR014729 (9.2%)" "Aminoacyl-tRNA synthetase, class Ia (9.2%) Valine-tRNA ligase (9.2%) Rossmann-like alpha/beta/alpha sandwich fold (9.2%)" VVLELDNVRR Pseudomonadati Bacteria Pseudomonadati "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (19.2%) IPR003593 (19.2%) IPR017871 (19.2%)" "ABC transporter-like, ATP-binding domain (19.2%) AAA+ ATPase domain (19.2%) ABC transporter-like, conserved site (19.2%)" YNVSLTK root "6.3.5.3 (21.4%) 3.1.3.1 (14.3%) 1.1.1.136 (7.1%)" "phosphoribosylformylglycinamidine synthase (21.4%) alkaline phosphatase (14.3%) UDP-N-acetylglucosamine 6-dehydrogenase (7.1%)" "GO:0045892 (6.4%) GO:0015833 (2%) GO:0006189 (1.6%)" "GO:0005886 (6.8%) GO:0016020 (6%) GO:0005737 (2%)" "GO:0008080 (12.4%) GO:0003677 (7.6%) GO:0003700 (6.4%)" "negative regulation of DNA-templated transcription (6.4%) peptide transport (2%) 'de novo' IMP biosynthetic process (1.6%)" "plasma membrane (6.8%) membrane (6%) cytoplasm (2%)" "N-acetyltransferase activity (12.4%) DNA binding (7.6%) DNA-binding transcription factor activity (6.4%)" "IPR016181 (6.6%) IPR000182 (6.4%) IPR050769 (6.4%)" "Acyl-CoA N-acyltransferase (6.6%) GNAT domain (6.4%) N-acetyltransferase, camello-type (6.4%)" LAELQQGLDDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SVQLPDGR root "2.7.7.8 (69.6%) 2.7.13.3 (8.7%) 3.1.26.11 (8.7%)" "polyribonucleotide nucleotidyltransferase (69.6%) histidine kinase (8.7%) ribonuclease Z (8.7%)" "GO:0006396 (8.2%) GO:0006402 (8.2%) GO:0008360 (0.5%)" "GO:0005829 (8.4%) GO:0005615 (7.4%) GO:0031012 (7.4%)" "GO:0000175 (8.2%) GO:0000287 (8.2%) GO:0003723 (8.2%)" "RNA processing (8.2%) mRNA catabolic process (8.2%) regulation of cell shape (0.5%)" "cytosol (8.4%) extracellular space (7.4%) extracellular matrix (7.4%)" "3'-5'-RNA exonuclease activity (8.2%) magnesium ion binding (8.2%) RNA binding (8.2%)" "IPR001247 (4.6%) IPR003029 (4.6%) IPR004087 (4.6%)" "Exoribonuclease, phosphorolytic domain 1 (4.6%) S1 domain (4.6%) K Homology domain (4.6%)" ENNFFPNFLGEALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25%) IPR010982 (25%) IPR028082 (25%)" "LacI-type HTH domain (25%) Lambda repressor-like, DNA-binding domain superfamily (25%) Periplasmic binding protein-like I (25%)" GKDSFEAATLHVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0008643 (33.3%) GO:0016020 (33.3%) GO:0015288 (33.3%) carbohydrate transport (33.3%) membrane (33.3%) porin activity (33.3%) "IPR007049 (50.7%) IPR038673 (49.3%)" "Carbohydrate-selective porin OprB (50.7%) Carbohydrate-selective porin OprB superfamily (49.3%)" NAQVATCEWEPVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.7%) IPR012000 (12.7%) IPR012001 (12.7%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.7%) Thiamine pyrophosphate enzyme, central domain (12.7%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.7%)" QQLVLTGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" ATSAETYAQLEQDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DLFMVPEEFELPNVSLATYVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (25.6%) IPR003593 (25.6%) IPR051782 (24.8%)" "ABC transporter-like, ATP-binding domain (25.6%) AAA+ ATPase domain (25.6%) ABC Transporter Superfamily, Various Functions (24.8%)" SVYDLVLEQGLMSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.1.1 (100%) aspartate ammonia-lyase (100%) "GO:0006099 (25%) GO:0006531 (25%)" GO:0005829 (25%) GO:0008797 (25%) "tricarboxylic acid cycle (25%) aspartate metabolic process (25%)" cytosol (25%) aspartate ammonia-lyase activity (25%) "IPR018951 (14.3%) IPR020557 (14.3%) IPR022761 (14.3%)" "Fumarase C, C-terminal (14.3%) Fumarate lyase, conserved site (14.3%) Fumarate lyase, N-terminal (14.3%)" LNEAFEQMPEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (50%) IPR027417 (50%)" "Tetraacyldisaccharide 4'-kinase (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" KYVEPLLTR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006412 (33.1%) GO:0006281 (0.3%)" GO:0022625 (33.1%) "GO:0003735 (33.1%) GO:0000166 (0.3%) GO:0003677 (0.3%)" "translation (33.1%) DNA repair (0.3%)" cytosolic large ribosomal subunit (33.1%) "structural constituent of ribosome (33.1%) nucleotide binding (0.3%) DNA binding (0.3%)" "IPR000456 (33.4%) IPR036373 (33.2%) IPR047859 (32.9%)" "Large ribosomal subunit protein bL17 (33.4%) Large ribosomal subunit protein bL17 superfamily (33.2%) Large ribosomal subunit protein bL17, conserved site (32.9%)" AQVAQAEAALVSAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" GSVMLSELAEDGQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ALGAEQVPYFR Bacteria Bacteria "1.12.-.- (66.7%) 2.6.1.37 (33.3%)" "Acting on hydrogen as donors (66.7%) 2-aminoethylphosphonate--pyruvate transaminase (33.3%)" "GO:0008483 (91.9%) GO:0016491 (5.4%) GO:0047304 (2.7%)" "transaminase activity (91.9%) oxidoreductase activity (5.4%) 2-aminoethylphosphonate-pyruvate transaminase activity (2.7%)" "IPR000192 (19.8%) IPR015421 (19.8%) IPR015424 (19.8%)" "Aminotransferase class V domain (19.8%) Pyridoxal phosphate-dependent transferase, major domain (19.8%) Pyridoxal phosphate-dependent transferase (19.8%)" MLDMVTR root "3.6.5.- (92.9%) 4.6.1.2 (5.3%) 1.1.1.262 (0.6%)" "Acting on GTP; involved in cellular and subcellular movement (92.9%) guanylate cyclase (5.3%) 4-hydroxythreonine-4-phosphate dehydrogenase (0.6%)" "GO:0009409 (8.6%) GO:0000027 (8.3%) GO:0010467 (8.1%)" "GO:0005829 (8.7%) GO:1990904 (8.6%) GO:0005886 (0.6%)" "GO:0005525 (9.2%) GO:0003924 (8.6%) GO:0000049 (8.3%)" "response to cold (8.6%) ribosomal large subunit assembly (8.3%) gene expression (8.1%)" "cytosol (8.7%) ribonucleoprotein complex (8.6%) plasma membrane (0.6%)" "GTP binding (9.2%) GTPase activity (8.6%) tRNA binding (8.3%)" "IPR000640 (6%) IPR027417 (6%) IPR035647 (6%)" "Elongation factor EFG, domain V-like (6%) P-loop containing nucleoside triphosphate hydrolase (6%) EF-G domain III/V-like (6%)" FNNADGQLSFELDENSPVNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" LHSFAVGLK root 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) "GO:0006529 (25.7%) GO:0035556 (0.1%)" GO:0005829 (22.5%) "GO:0004066 (25.7%) GO:0005524 (25.6%) GO:0016874 (0.3%)" "obsolete asparagine biosynthetic process (25.7%) intracellular signal transduction (0.1%)" cytosol (22.5%) "asparagine synthase (glutamine-hydrolyzing) activity (25.7%) ATP binding (25.6%) ligase activity (0.3%)" "IPR001962 (14.4%) IPR050795 (14.4%) IPR014729 (14.4%)" "Asparagine synthase (14.4%) Asparagine Synthetase (14.4%) Rossmann-like alpha/beta/alpha sandwich fold (14.4%)" LSEDQLFYCNQR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0016226 (99.6%) GO:1990229 (0.4%) iron-sulfur cluster assembly (99.6%) iron-sulfur cluster assembly complex (0.4%) "IPR000825 (20.2%) IPR055346 (20.2%) IPR037284 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.2%) SUF system FeS cluster assembly, SufBD (20.2%) SUF system FeS cluster assembly, SufBD superfamily (20.1%)" LTQDGWDVYAACANTGGFSAEQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.5%) IPR018223 (14.5%) IPR023434 (14.5%)" "Argininosuccinate synthase (14.5%) Argininosuccinate synthase, conserved site (14.5%) Argininosuccinate synthase, type 1 subfamily (14.5%)" KYQQLQNQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025380 (100%) Domain of unknown function DUF4369 (100%) ESLLLDLK root "3.6.4.13 (66.7%) 6.1.1.17 (4.3%) 2.4.1.- (3.2%)" "RNA helicase (66.7%) glutamate--tRNA ligase (4.3%) Hexosyltransferases (3.2%)" "GO:0007517 (6.6%) GO:0030154 (6.6%) GO:0010468 (3.9%)" "GO:0005901 (6.6%) GO:0005737 (4.3%) GO:0030017 (4.1%)" "GO:0005524 (3.6%) GO:0008270 (3.1%) GO:0003724 (2.7%)" "muscle organ development (6.6%) cell differentiation (6.6%) regulation of gene expression (3.9%)" "caveola (6.6%) cytoplasm (4.3%) sarcomere (4.1%)" "ATP binding (3.6%) zinc ion binding (3.1%) RNA helicase activity (2.7%)" "IPR026752 (10%) IPR027417 (5.3%) IPR001650 (4.3%)" "Cavin family (10%) P-loop containing nucleoside triphosphate hydrolase (5.3%) Helicase, C-terminal domain-like (4.3%)" KLLANLTSK root "6.1.1.20 (93.8%) 7.6.2.2 (6.3%)" "phenylalanine--tRNA ligase (93.8%) ABC-type xenobiotic transporter (6.3%)" "GO:0006432 (14.2%) GO:0000463 (1.9%) GO:0000466 (1.9%)" "GO:0009328 (14.2%) GO:0005730 (1.9%) GO:0005886 (1.9%)" "GO:0005524 (15.1%) GO:0000049 (14.2%) GO:0000287 (14.2%)" "phenylalanyl-tRNA aminoacylation (14.2%) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (1.9%) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (1.9%)" "phenylalanine-tRNA ligase complex (14.2%) nucleolus (1.9%) plasma membrane (1.9%)" "ATP binding (15.1%) tRNA binding (14.2%) magnesium ion binding (14.2%)" "IPR002547 (6.9%) IPR004532 (6.9%) IPR005121 (6.9%)" "tRNA-binding domain (6.9%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (6.9%) Ferrodoxin-fold anticodon-binding domain (6.9%)" NDNKEGWDNLDLFGWMGYPMQLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (27.6%) GO:0008654 (27.6%)" GO:0016020 (17.2%) GO:0004512 (27.6%) "inositol biosynthetic process (27.6%) phospholipid biosynthetic process (27.6%)" membrane (17.2%) inositol-3-phosphate synthase activity (27.6%) "IPR002587 (33.5%) IPR013021 (33.5%) IPR036291 (33.1%)" "Myo-inositol-1-phosphate synthase (33.5%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.5%) NAD(P)-binding domain superfamily (33.1%)" DELTQLLAELK root 4.3.2.1 (100%) argininosuccinate lyase (100%) GO:0042450 (32.4%) GO:0005829 (32.4%) "GO:0004056 (32.4%) GO:0008270 (1.5%) GO:0061630 (1.5%)" L-arginine biosynthetic process via ornithine (32.4%) cytosol (32.4%) "argininosuccinate lyase activity (32.4%) zinc ion binding (1.5%) ubiquitin protein ligase activity (1.5%)" "IPR009049 (16.7%) IPR022761 (16.7%) IPR000362 (15.9%)" "Argininosuccinate lyase (16.7%) Fumarate lyase, N-terminal (16.7%) Fumarate lyase family (15.9%)" VYADPSLGLSPALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (11.1%) GO:0008360 (11.1%) GO:0009252 (11.1%)" "GO:0005886 (11.1%) GO:0030288 (11.1%)" "GO:0004180 (11.1%) GO:0008658 (11.1%) GO:0008955 (11.1%)" "proteolysis (11.1%) regulation of cell shape (11.1%) peptidoglycan biosynthetic process (11.1%)" "plasma membrane (11.1%) outer membrane-bounded periplasmic space (11.1%)" "carboxypeptidase activity (11.1%) penicillin binding (11.1%) peptidoglycan glycosyltransferase activity (11.1%)" "IPR001264 (16.7%) IPR001460 (16.7%) IPR012338 (16.7%)" "Glycosyl transferase, family 51 (16.7%) Penicillin-binding protein, transpeptidase (16.7%) Beta-lactamase/transpeptidase-like (16.7%)" ALFQLALGR root "3.1.-.- (49.5%) 3.6.4.- (49.5%) 3.6.4.13 (1%)" "Acting on ester bonds (49.5%) Acting on ATP; involved in cellular and subcellular movement (49.5%) RNA helicase (1%)" "GO:0006298 (9.8%) GO:0045910 (9.8%) GO:0072344 (9.8%)" "GO:0005737 (0.6%) GO:0005681 (0.2%) GO:0016020 (0.2%)" "GO:0005524 (10%) GO:0004519 (9.8%) GO:0016887 (9.8%)" "mismatch repair (9.8%) negative regulation of DNA recombination (9.8%) rescue of stalled ribosome (9.8%)" "cytoplasm (0.6%) spliceosomal complex (0.2%) membrane (0.2%)" "ATP binding (10%) endonuclease activity (9.8%) ATP hydrolysis activity (9.8%)" "IPR000432 (10.8%) IPR002625 (10.8%) IPR005747 (10.8%)" "DNA mismatch repair protein MutS, C-terminal (10.8%) Smr domain (10.8%) Endonuclease MutS2 (10.8%)" LQEMQSEHLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) LDNVKDGAVLVFSYLGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.6%) IPR012910 (13.6%) IPR037066 (13.6%)" "Carboxypeptidase-like, regulatory domain superfamily (13.6%) TonB-dependent receptor, plug domain (13.6%) TonB-dependent receptor, plug domain superfamily (13.6%)" GGEQLEGMFTGNVLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) SCPFDLHNFSGWCMVTSTFYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032283 (34.8%) IPR038081 (34.8%) IPR032299 (30.4%)" "Domain of unknown function DUF4984 (34.8%) CalX-like domain superfamily (34.8%) Protein of unknown function DUF4843 (30.4%)" TDKQVDHESMAQDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006352 (36.4%) "GO:0003677 (27.3%) GO:0016987 (27.3%) GO:0003700 (9.1%)" DNA-templated transcription initiation (36.4%) "DNA binding (27.3%) sigma factor activity (27.3%) DNA-binding transcription factor activity (9.1%)" "IPR007630 (12.9%) IPR050239 (12.9%) IPR000943 (9.7%)" "RNA polymerase sigma-70 region 4 (12.9%) Sigma-70 factor family, RNA polymerase initiation factors (12.9%) RNA polymerase sigma-70 (9.7%)" TFRPDLDYGNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.3.1.98 (100%) UDP-N-acetylmuramate dehydrogenase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0051301 (14.3%)" GO:0005829 (14.3%) "GO:0008762 (14.3%) GO:0071949 (13.7%) GO:0050660 (0.5%)" "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) cell division (14.3%)" cytosol (14.3%) "UDP-N-acetylmuramate dehydrogenase activity (14.3%) FAD binding (13.7%) flavin adenine dinucleotide binding (0.5%)" "IPR003170 (12.6%) IPR006094 (12.6%) IPR011601 (12.6%)" "UDP-N-acetylenolpyruvoylglucosamine reductase (12.6%) FAD linked oxidase, N-terminal (12.6%) UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal (12.6%)" LNYTYTR root "2.4.2.9 (50%) 3.2.2.31 (50%)" "uracil phosphoribosyltransferase (50%) adenine glycosylase (50%)" "GO:0006412 (6.1%) GO:0044718 (4.9%) GO:0006298 (2.4%)" "GO:0016020 (20.7%) GO:0009279 (15.9%) GO:0022627 (6.1%)" "GO:0003735 (6.1%) GO:0019843 (6.1%) GO:0015344 (4.9%)" "translation (6.1%) siderophore transmembrane transport (4.9%) mismatch repair (2.4%)" "membrane (20.7%) cell outer membrane (15.9%) cytosolic small ribosomal subunit (6.1%)" "structural constituent of ribosome (6.1%) rRNA binding (6.1%) siderophore uptake transmembrane transporter activity (4.9%)" "IPR021840 (7%) IPR002035 (5.8%) IPR036465 (5.8%)" "Protein of unknown function DUF3433 (7%) von Willebrand factor, type A (5.8%) von Willebrand factor A-like domain superfamily (5.8%)" AASMADSKADEGTNNSLSPTFLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR011990 (33.3%) IPR018704 (33.3%) IPR019734 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) Ancillary SecYEG translocon subunit/Cell division coordinator CpoB, TPR domain (33.3%) Tetratricopeptide repeat (33.3%)" VLFCDDSLVR Bacteria Bacteria 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (20.1%) GO:0006189 (13.3%) GO:0006164 (6.8%)" "GO:0004044 (20.1%) GO:0046872 (19.6%) GO:0051536 (19.6%)" "purine nucleobase biosynthetic process (20.1%) 'de novo' IMP biosynthetic process (13.3%) purine nucleotide biosynthetic process (6.8%)" "amidophosphoribosyltransferase activity (20.1%) metal ion binding (19.6%) iron-sulfur cluster binding (19.6%)" "IPR000836 (20.7%) IPR017932 (20.2%) IPR029057 (20.2%)" "Phosphoribosyltransferase domain (20.7%) Glutamine amidotransferase type 2 domain (20.2%) Phosphoribosyltransferase-like (20.2%)" MRQEDPTWLVDQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.7%) IPR000795 (7.7%) IPR005225 (7.7%)" "Elongation factor EFG, domain V-like (7.7%) Translational (tr)-type GTP-binding domain (7.7%) Small GTP-binding domain (7.7%)" ALPQLLAELDPHSVYLSAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.21.- (71.4%) 3.4.21.102 (28.6%)" "Serine endopeptidases (71.4%) C-terminal processing peptidase (28.6%)" "GO:0006508 (17.8%) GO:0007165 (17.8%)" "GO:0030288 (17.8%) GO:0016020 (11.4%)" "GO:0004175 (17.5%) GO:0008236 (17.5%) GO:0004252 (0.3%)" "proteolysis (17.8%) signal transduction (17.8%)" "outer membrane-bounded periplasmic space (17.8%) membrane (11.4%)" "endopeptidase activity (17.5%) serine-type peptidase activity (17.5%) serine-type endopeptidase activity (0.3%)" "IPR001478 (19.8%) IPR004447 (19.8%) IPR005151 (19.8%)" "PDZ domain (19.8%) C-terminal-processing peptidase S41A (19.8%) Tail specific protease (19.8%)" LDASNQQPPVDQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012640 (50%) IPR024361 (50%)" "Membrane lipoprotein, lipid attachment site (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" PAFGGNLVATLVNPDHRPQMATVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.8.1 (100%) short-chain acyl-CoA dehydrogenase (100%) GO:0033539 (33.2%) "GO:0009055 (33.2%) GO:0050660 (33.2%) GO:0016937 (0.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.2%) "electron transfer activity (33.2%) flavin adenine dinucleotide binding (33.2%) short-chain fatty acyl-CoA dehydrogenase activity (0.3%)" "IPR001308 (16.7%) IPR014730 (16.7%) IPR014731 (16.7%)" "Electron transfer flavoprotein alpha subunit/FixB (16.7%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (16.7%) Electron transfer flavoprotein, alpha subunit, C-terminal (16.7%)" RLPSQAGLGGGSADAAFMLR Pseudomonadati Bacteria Pseudomonadati 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (23.8%) GO:0019288 (23.8%)" "GO:0005524 (26.2%) GO:0050515 (26.2%)" "terpenoid biosynthetic process (23.8%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (23.8%)" "ATP binding (26.2%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (26.2%)" "IPR006204 (17.5%) IPR014721 (17.5%) IPR020568 (17.5%)" "GHMP kinase N-terminal domain (17.5%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17.5%) Ribosomal protein uS5 domain 2-type superfamily (17.5%)" VPENGVLTLLVSPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) ESGFELK root "5.3.1.12 (78.9%) 3.2.1.21 (5.4%) 5.4.99.2 (5%)" "glucuronate isomerase (78.9%) beta-glucosidase (5.4%) methylmalonyl-CoA mutase (5%)" "GO:0019698 (15.8%) GO:0042840 (15.8%) GO:0009073 (0.8%)" "GO:0005737 (2.1%) GO:0016020 (2%) GO:0005886 (1.3%)" "GO:0008880 (15.8%) GO:0003676 (1.4%) GO:0046872 (1.3%)" "D-galacturonate catabolic process (15.8%) D-glucuronate catabolic process (15.8%) aromatic amino acid family biosynthetic process (0.8%)" "cytoplasm (2.1%) membrane (2%) plasma membrane (1.3%)" "glucuronate isomerase activity (15.8%) nucleic acid binding (1.4%) metal ion binding (1.3%)" "IPR003766 (15.8%) IPR032466 (15.6%) IPR013783 (1.2%)" "Uronate isomerase (15.8%) Metal-dependent hydrolase (15.6%) Immunoglobulin-like fold (1.2%)" ELVNKDNPQVLELWNLVFMQYNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14.1%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14.1%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.3%) IPR018165 (9.3%) IPR050058 (9.3%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.3%) Alanyl-tRNA synthetase, class IIc, core domain (9.3%) Alanine--tRNA ligase (9.3%)" SPLTETVH root 2.7.7.43 (100%) N-acylneuraminate cytidylyltransferase (100%) "GO:0045892 (14.4%) GO:1900376 (14.4%) GO:0007165 (5.6%)" "GO:0005856 (5.6%) GO:0005634 (4.4%) GO:0005737 (1.1%)" "GO:0000976 (14.4%) GO:0003700 (14.4%) GO:0008270 (14.4%)" "negative regulation of DNA-templated transcription (14.4%) regulation of secondary metabolite biosynthetic process (14.4%) signal transduction (5.6%)" "cytoskeleton (5.6%) nucleus (4.4%) cytoplasm (1.1%)" "transcription cis-regulatory region binding (14.4%) DNA-binding transcription factor activity (14.4%) zinc ion binding (14.4%)" "IPR002481 (13.1%) IPR036388 (13.1%) IPR036390 (13.1%)" "Ferric-uptake regulator (13.1%) Winged helix-like DNA-binding domain superfamily (13.1%) Winged helix DNA-binding domain superfamily (13.1%)" VGHFLAEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025665 (70.3%) IPR011250 (29.7%)" "Outer membrane protein, beta-barrel domain 2 (70.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (29.7%)" LENYGDLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0033388 (42.1%) "GO:0050126 (42.1%) GO:0016746 (15.8%)" putrescine biosynthetic process from arginine (42.1%) "N-carbamoylputrescine amidase activity (42.1%) acyltransferase activity (15.8%)" "IPR003010 (33.3%) IPR036526 (33.3%) IPR050345 (33.3%)" "Carbon-nitrogen hydrolase (33.3%) Carbon-nitrogen hydrolase superfamily (33.3%) Aliphatic Amidase/Beta-Ureidopropionase (33.3%)" RGEAYDEEELAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (15.5%) GO:0008360 (12.7%) GO:0009252 (12.7%)" GO:0005737 (12.7%) "GO:0005524 (15.5%) GO:0008716 (15.5%) GO:0046872 (15.5%)" "cell wall organization (15.5%) regulation of cell shape (12.7%) peptidoglycan biosynthetic process (12.7%)" cytoplasm (12.7%) "ATP binding (15.5%) D-alanine-D-alanine ligase activity (15.5%) metal ion binding (15.5%)" "IPR000291 (14.7%) IPR005905 (14.7%) IPR011095 (14.7%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.7%) D-alanine--D-alanine ligase (14.7%) D-alanine--D-alanine ligase, C-terminal (14.7%)" LFDDTMNLLAEADLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" LALFYFK root "2.3.2.27 (47.6%) 2.7.13.3 (9.5%) 3.4.23.- (9.5%)" "RING-type E3 ubiquitin transferase (47.6%) histidine kinase (9.5%) Aspartic endopeptidases (9.5%)" "GO:0080120 (3.1%) GO:0006508 (2.8%) GO:0016562 (2%)" "GO:0016020 (22.6%) GO:0005886 (5.5%) GO:0005778 (2%)" "GO:0004175 (3.1%) GO:0015109 (2.4%) GO:0008270 (2.2%)" "CAAX-box protein maturation (3.1%) proteolysis (2.8%) protein import into peroxisome matrix, receptor recycling (2%)" "membrane (22.6%) plasma membrane (5.5%) peroxisomal membrane (2%)" "endopeptidase activity (3.1%) chromate transmembrane transporter activity (2.4%) zinc ion binding (2.2%)" "IPR003672 (9.4%) IPR000620 (5.8%) IPR003675 (3.6%)" "CobN/magnesium chelatase (9.4%) EamA domain (5.8%) CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain (3.6%)" DGNPTTTESSTALDREPLVQVLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (66.7%) IPR008160 (33.3%)" "Domain of unknown function DUF4988 (66.7%) Collagen triple helix repeat (33.3%)" LTLLNNWENTGFDFNQQSLAELMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" FSLAYAAK root "3.1.3.18 (94.7%) 4.1.1.37 (5.3%)" "phosphoglycolate phosphatase (94.7%) uroporphyrinogen decarboxylase (5.3%)" "GO:0006281 (15.6%) GO:0009247 (1.6%) GO:0006886 (0.8%)" "GO:0005829 (16.4%) GO:0005886 (3.3%) GO:0005741 (2.5%)" "GO:0008967 (15.6%) GO:2001070 (15.6%) GO:0008308 (2.5%)" "DNA repair (15.6%) glycolipid biosynthetic process (1.6%) intracellular protein transport (0.8%)" "cytosol (16.4%) plasma membrane (3.3%) mitochondrial outer membrane (2.5%)" "phosphoglycolate phosphatase activity (15.6%) starch binding (15.6%) voltage-gated monoatomic anion channel activity (2.5%)" "IPR002044 (7.9%) IPR006439 (7.9%) IPR006549 (7.9%)" "Carbohydrate binding module family 20 (7.9%) HAD hydrolase, subfamily IA (7.9%) HAD-superfamily hydrolase,subfamily IIIA (7.9%)" LTFGSKPSGLANPDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" NETANTVALQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (66.7%) IPR008160 (33.3%)" "Domain of unknown function DUF4988 (66.7%) Collagen triple helix repeat (33.3%)" ELYNLAQTLDLDTDKFFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) TLAYVGDGLNDAPVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) "GO:0005886 (16.1%) GO:0016020 (0.8%)" "GO:0005524 (16.9%) GO:0015086 (16.9%) GO:0016887 (16.9%)" "plasma membrane (16.1%) membrane (0.8%)" "ATP binding (16.9%) cadmium ion transmembrane transporter activity (16.9%) ATP hydrolysis activity (16.9%)" "IPR001757 (10.5%) IPR051014 (10.5%) IPR018303 (10.2%)" "P-type ATPase (10.5%) Cation Transport ATPase Type IB (10.5%) P-type ATPase, phosphorylation site (10.2%)" LQQLLADK root "2.7.13.3 (29.2%) 2.7.7.6 (6.3%) 2.7.9.3 (6.3%)" "histidine kinase (29.2%) DNA-directed RNA polymerase (6.3%) selenide, water dikinase (6.3%)" "GO:0030435 (5.7%) GO:0009086 (3.1%) GO:0032259 (3.1%)" "GO:0016020 (2.8%) GO:0005737 (2.5%) GO:0005886 (2.5%)" "GO:0005524 (4.5%) GO:0046872 (3.7%) GO:0008270 (3.1%)" "sporulation resulting in formation of a cellular spore (5.7%) methionine biosynthetic process (3.1%) methylation (3.1%)" "membrane (2.8%) cytoplasm (2.5%) plasma membrane (2.5%)" "ATP binding (4.5%) metal ion binding (3.7%) zinc ion binding (3.1%)" "IPR001173 (3.1%) IPR013486 (3.1%) IPR013693 (3.1%)" "Glycosyltransferase 2-like (3.1%) Sporulation stage II protein D, amidase enhancer LytB (3.1%) Sporulation stage II protein D, amidase enhancer LytB N-terminal (3.1%)" ELLFPLRQDGVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" HNLVLFTWGNVSGLDR Bacteria Bacteria 5.1.3.4 (100%) L-ribulose-5-phosphate 4-epimerase (100%) GO:0019323 (20.2%) GO:0005829 (20.2%) "GO:0008742 (20.2%) GO:0016832 (20.2%) GO:0046872 (19.1%)" pentose catabolic process (20.2%) cytosol (20.2%) "L-ribulose-phosphate 4-epimerase activity (20.2%) aldehyde-lyase activity (20.2%) metal ion binding (19.1%)" "IPR001303 (33.3%) IPR036409 (33.3%) IPR050197 (33.3%)" "Class II aldolase/adducin N-terminal (33.3%) Class II aldolase/adducin N-terminal domain superfamily (33.3%) Aldolase class II family, sugar metabolism enzymes (33.3%)" DGVNEDVLK Bacteria Bacteria "GO:0006428 (5.9%) GO:0008299 (5.9%)" GO:0005737 (5.9%) "GO:0005506 (29.4%) GO:0004601 (23.5%) GO:0002161 (5.9%)" "isoleucyl-tRNA aminoacylation (5.9%) isoprenoid biosynthetic process (5.9%)" cytoplasm (5.9%) "iron ion binding (29.4%) peroxidase activity (23.5%) aminoacyl-tRNA deacylase activity (5.9%)" "IPR003251 (10%) IPR009040 (10%) IPR009078 (10%)" "Rubrerythrin, diiron-binding domain (10%) Ferritin-like diiron domain (10%) Ferritin-like superfamily (10%)" LLGNDDLGLVSNLTNLLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.7.2 (100%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (100%) GO:0015969 (42%) GO:0005886 (42%) "GO:0016787 (12.3%) GO:0008893 (2.5%) GO:0016301 (1.2%)" guanosine tetraphosphate metabolic process (42%) plasma membrane (42%) "hydrolase activity (12.3%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (2.5%) kinase activity (1.2%)" "IPR002912 (10.1%) IPR004095 (10.1%) IPR004811 (10.1%)" "ACT domain (10.1%) TGS (10.1%) RelA/SpoT family (10.1%)" MHLEFAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) DLMQYLLPQDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0051301 (10.3%) GO:0051603 (10.3%)" GO:0009376 (10.3%) "GO:0005524 (10.3%) GO:0016887 (10.3%) GO:0008233 (9.7%)" "cell division (10.3%) proteolysis involved in protein catabolic process (10.3%)" HslUV protease complex (10.3%) "ATP binding (10.3%) ATP hydrolysis activity (10.3%) peptidase activity (9.7%)" "IPR019489 (11.7%) IPR050052 (11.7%) IPR003593 (11%)" "Clp ATPase, C-terminal (11.7%) ATP-dependent Clp protease ATP-binding subunit ClpX (11.7%) AAA+ ATPase domain (11%)" HNNWSLCTDTGVLLHAAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" YEFNNEFQQEFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (12.6%) GO:0044210 (12.6%)" "GO:0005829 (12.6%) GO:0097268 (11.7%)" "GO:0003883 (12.6%) GO:0005524 (12.6%) GO:0042802 (12.6%)" "pyrimidine nucleobase biosynthetic process (12.6%) 'de novo' CTP biosynthetic process (12.6%)" "cytosol (12.6%) cytoophidium (11.7%)" "CTP synthase activity (12.6%) ATP binding (12.6%) identical protein binding (12.6%)" "IPR004468 (17.8%) IPR017926 (17.8%) IPR017456 (16.4%)" "CTP synthase (17.8%) Glutamine amidotransferase (17.8%) CTP synthase, N-terminal (16.4%)" HSVTSYEQVSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR003790 (25.6%) IPR052177 (25.6%) IPR013783 (24.4%)" "Glycosyl hydrolase-like 10 (25.6%) Divisome-localized Glycosyl Hydrolase (25.6%) Immunoglobulin-like fold (24.4%)" ADNPFFTPEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (37.5%) GO:0009341 (12.5%) "GO:0004565 (37.5%) GO:0016787 (12.5%)" carbohydrate metabolic process (37.5%) beta-galactosidase complex (12.5%) "beta-galactosidase activity (37.5%) hydrolase activity (12.5%)" "IPR040719 (33.7%) IPR031330 (31.3%) IPR017853 (30.1%)" "Domain of unknown function DUF5597 (33.7%) Glycoside hydrolase 35, catalytic domain (31.3%) Glycoside hydrolase superfamily (30.1%)" LDEATWMSAATK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" LFEEDKLYLNPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (29.4%) "GO:0003700 (35.3%) GO:0043565 (35.3%)" membrane (29.4%) "DNA-binding transcription factor activity (35.3%) sequence-specific DNA binding (35.3%)" "IPR018060 (46.2%) IPR009057 (43.6%) IPR020449 (10.3%)" "AraC-like, DNA binding HTH domain (46.2%) Homedomain-like superfamily (43.6%) Transcription regulator HTH, AraC- type, HTH domain (10.3%)" LFSAQVWNPEPYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (19.3%) GO:0005975 (0.7%)" GO:0005737 (20%) "GO:0003844 (20%) GO:0004553 (20%) GO:0043169 (20%)" "glycogen biosynthetic process (19.3%) carbohydrate metabolic process (0.7%)" cytoplasm (20%) "1,4-alpha-glucan branching enzyme activity (20%) hydrolase activity, hydrolyzing O-glycosyl compounds (20%) cation binding (20%)" "IPR004193 (12.8%) IPR006047 (12.8%) IPR006048 (12.8%)" "Glycoside hydrolase, family 13, N-terminal (12.8%) Glycosyl hydrolase family 13, catalytic domain (12.8%) Alpha-amylase/branching enzyme, C-terminal all beta (12.8%)" AQNLKVDDNDLMETAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.2%) GO:0043335 (15.2%) GO:0051083 (15.2%)" GO:0005737 (9.1%) "GO:0003755 (15.2%) GO:0043022 (15.2%) GO:0044183 (15.2%)" "protein transport (15.2%) protein unfolding (15.2%) 'de novo' cotranslational protein folding (15.2%)" cytoplasm (9.1%) "peptidyl-prolyl cis-trans isomerase activity (15.2%) ribosome binding (15.2%) protein folding chaperone (15.2%)" "IPR005215 (17.9%) IPR008881 (17.9%) IPR027304 (17.9%)" "Trigger factor (17.9%) Trigger factor, ribosome-binding, bacterial (17.9%) Trigger factor/SurA domain superfamily (17.9%)" VLTHELMNTLTPVTSLSETLLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0000160 (30.7%) GO:0016020 (29.9%) "GO:0016301 (31.4%) GO:0005524 (8%)" phosphorelay signal transduction system (30.7%) membrane (29.9%) "kinase activity (31.4%) ATP binding (8%)" "IPR000014 (17.3%) IPR003594 (16.9%) IPR005467 (16.9%)" "PAS domain (17.3%) Histidine kinase/HSP90-like ATPase domain (16.9%) Histidine kinase domain (16.9%)" LVGLDESGVVVSPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.33 (100%) pantothenate kinase (100%) GO:0015937 (25%) GO:0005829 (25%) "GO:0004594 (25%) GO:0005524 (25%)" coenzyme A biosynthetic process (25%) cytosol (25%) "pantothenate kinase activity (25%) ATP binding (25%)" "IPR004567 (50%) IPR043129 (50%)" "Type II pantothenate kinase (50%) ATPase, nucleotide binding domain (50%)" GYDGTLLK root "3.4.-.- (80%) 3.4.11.6 (20%)" "Acting on peptide bonds (peptidases) (80%) aminopeptidase B (20%)" "GO:0015979 (0.9%) GO:2000001 (0.9%)" "GO:0016020 (3.6%) GO:0005634 (0.9%) GO:0005829 (0.9%)" "GO:0008270 (40%) GO:0016603 (40%) GO:0016787 (3.6%)" "photosynthesis (0.9%) regulation of DNA damage checkpoint (0.9%)" "membrane (3.6%) nucleus (0.9%) cytosol (0.9%)" "zinc ion binding (40%) glutaminyl-peptide cyclotransferase activity (40%) hydrolase activity (3.6%)" "IPR007484 (40.4%) IPR040234 (40.4%) IPR015943 (1.8%)" "Peptidase M28 (40.4%) Glutaminyl-peptide cyclotransferase-like (40.4%) WD40/YVTN repeat-like-containing domain superfamily (1.8%)" MALALHPVSMQQLMDLADSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) LVLGFRPVASVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0030261 (25%) GO:0005829 (25%) "GO:0003677 (25%) GO:0030527 (25%)" chromosome condensation (25%) cytosol (25%) "DNA binding (25%) structural constituent of chromatin (25%)" "IPR000119 (53.8%) IPR010992 (46.2%)" "Histone-like DNA-binding protein (53.8%) Integration host factor (IHF)-like DNA-binding domain superfamily (46.2%)" LAYLLLDREYETAPENER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) LACLNETGELGSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045692 (100%) Protein of unknown function DUF6057 (100%) GDYDQMTWLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.1%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.1%)" "IPR004199 (6.8%) IPR006102 (6.8%) IPR006103 (6.8%)" "Beta galactosidase small chain/ domain 5 (6.8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.8%) Glycoside hydrolase family 2, catalytic domain (6.8%)" ANNQLEAFFNTSNSSTYLGDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" AEAQALLGHYPEALNDLNTELAAFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" NNFYWQDYLGDLDYVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (38.2%) GO:0000272 (11.8%)" "GO:0004553 (38.2%) GO:0031176 (11.8%)" "xylan catabolic process (38.2%) polysaccharide catabolic process (11.8%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (38.2%) endo-1,4-beta-xylanase activity (11.8%)" "IPR001000 (29.3%) IPR017853 (25.9%) IPR044846 (25.9%)" "Glycoside hydrolase family 10 domain (29.3%) Glycoside hydrolase superfamily (25.9%) Glycoside hydrolase family 10 (25.9%)" GTSLDQLASLELNGATVEAADFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" WLLSGWDNPVTCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004674 (100%) protein serine/threonine kinase activity (100%) "IPR024361 (22%) IPR013783 (20.7%) IPR032675 (20.7%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (22%) Immunoglobulin-like fold (20.7%) Leucine-rich repeat domain superfamily (20.7%)" LEGVGPMNYEDCLNYAVTGPAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (55.6%) 1.6.5.9 (44.4%)" "Transferred entry: 1.6.5.9 (55.6%) NADH:ubiquinone reductase (non-electrogenic) (44.4%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" YYDLTVEQLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016787 (100%) hydrolase activity (100%) "IPR001466 (34.2%) IPR050491 (34.2%) IPR012338 (31.6%)" "Beta-lactamase-related (34.2%) Beta-lactamase AmpC-like (34.2%) Beta-lactamase/transpeptidase-like (31.6%)" GLVVLKPSGVDYDTMK Bacteria Bacteria 5.1.3.4 (100%) L-ribulose-5-phosphate 4-epimerase (100%) "GO:0019568 (11%) GO:0019323 (8.5%) GO:0019572 (0.6%)" GO:0005829 (20.1%) "GO:0008742 (20.1%) GO:0016832 (20.1%) GO:0046872 (18.9%)" "arabinose catabolic process (11%) pentose catabolic process (8.5%) L-arabinose catabolic process (0.6%)" cytosol (20.1%) "L-ribulose-phosphate 4-epimerase activity (20.1%) aldehyde-lyase activity (20.1%) metal ion binding (18.9%)" "IPR001303 (33%) IPR036409 (33%) IPR050197 (33%)" "Class II aldolase/adducin N-terminal (33%) Class II aldolase/adducin N-terminal domain superfamily (33%) Aldolase class II family, sugar metabolism enzymes (33%)" LADLLTTGAALDFVLPDLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (57.1%) 1.6.5.9 (42.9%)" "Transferred entry: 1.6.5.9 (57.1%) NADH:ubiquinone reductase (non-electrogenic) (42.9%)" GO:0005886 (25%) "GO:0048038 (25%) GO:0051287 (25%) GO:0008137 (24.2%)" plasma membrane (25%) "quinone binding (25%) NAD binding (25%) NADH dehydrogenase (ubiquinone) activity (24.2%)" "IPR001135 (20.1%) IPR022885 (20.1%) IPR029014 (20.1%)" "NADH-quinone oxidoreductase, subunit D (20.1%) NAD(P)H-quinone oxidoreductase subunit D/H (20.1%) [NiFe]-hydrogenase, large subunit (20.1%)" TLEGMVLSQPLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000723 (25%) GO:0006281 (25%)" GO:0016020 (25%) GO:0003678 (25%) "telomere maintenance (25%) DNA repair (25%)" membrane (25%) DNA helicase activity (25%) "IPR003593 (20.1%) IPR010285 (20.1%) IPR029491 (20.1%)" "AAA+ ATPase domain (20.1%) DNA helicase Pif1-like, DEAD-box helicase domain (20.1%) Helicase Helix-turn-helix domain (20.1%)" KAAFEAALTR Bacteria Bacteria "1.8.4.11 (50%) 6.6.1.2 (50%)" "peptide-methionine (S)-S-oxide reductase (50%) cobaltochelatase (50%)" GO:0016020 (95.2%) "GO:0008113 (2.4%) GO:0051116 (2.4%)" membrane (95.2%) "peptide-methionine (S)-S-oxide reductase activity (2.4%) cobaltochelatase activity (2.4%)" "IPR003672 (95.6%) IPR002569 (2.2%) IPR036509 (2.2%)" "CobN/magnesium chelatase (95.6%) Peptide methionine sulphoxide reductase MsrA domain (2.2%) Peptide methionine sulphoxide reductase MsrA superfamily (2.2%)" ELKDVELGECK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) "GO:0004252 (48.3%) GO:0008239 (1.7%)" proteolysis (50%) "serine-type endopeptidase activity (48.3%) dipeptidyl-peptidase activity (1.7%)" "IPR001375 (34.1%) IPR029058 (32.9%) IPR011042 (31.7%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.1%) Alpha/Beta hydrolase fold (32.9%) Six-bladed beta-propeller, TolB-like (31.7%)" LDFCSTGNSGMATAGSGDVLTGLLTGLLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.2.1.136 (50%) 5.1.99.6 (50%)" "ADP-dependent NAD(P)H-hydrate dehydratase (50%) NAD(P)H-hydrate epimerase (50%)" "GO:0046496 (16.7%) GO:0110051 (16.7%)" "GO:0005524 (16.7%) GO:0046872 (16.7%) GO:0052855 (16.7%)" "nicotinamide nucleotide metabolic process (16.7%) metabolite repair (16.7%)" "ATP binding (16.7%) metal ion binding (16.7%) ADP-dependent NAD(P)H-hydrate dehydratase activity (16.7%)" "IPR000631 (16.7%) IPR004443 (16.7%) IPR017953 (16.7%)" "ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase (16.7%) YjeF N-terminal domain (16.7%) Carbohydrate kinase, predicted, conserved site (16.7%)" PATLETGAEVR root GO:0043043 (33.3%) GO:0005829 (33.3%) GO:0003746 (33.3%) peptide biosynthetic process (33.3%) cytosol (33.3%) translation elongation factor activity (33.3%) "IPR012340 (11.3%) IPR013852 (11.3%) IPR015365 (11.3%)" "Nucleic acid-binding, OB-fold (11.3%) Translation elongation factor P/YeiP, conserved site (11.3%) Elongation factor P, C-terminal (11.3%)" TDALMLSGETASGKYPVEAVQTMAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (4.5%) "GO:0000287 (19.1%) GO:0004743 (19.1%) GO:0005524 (19.1%)" response to stress (4.5%) "magnesium ion binding (19.1%) pyruvate kinase activity (19.1%) ATP binding (19.1%)" "IPR001697 (11.3%) IPR015793 (11.3%) IPR015795 (11.3%)" "Pyruvate kinase (11.3%) Pyruvate kinase, barrel (11.3%) Pyruvate kinase, C-terminal (11.3%)" YKPETYTLEDETGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0008654 (19.5%) GO:0005886 (20.3%) "GO:0005524 (20.3%) GO:0016301 (20.3%) GO:0046872 (19.5%)" phospholipid biosynthetic process (19.5%) plasma membrane (20.3%) "ATP binding (20.3%) kinase activity (20.3%) metal ion binding (19.5%)" "IPR001206 (17.2%) IPR045540 (17.2%) IPR050187 (17.2%)" "Diacylglycerol kinase, catalytic domain (17.2%) YegS/DAGK, C-terminal domain (17.2%) Lipid Phosphate Formation and Regulation (17.2%)" LLLLQNNSGDTNESK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) KLELDHLK root "3.6.5.- (71.4%) 4.1.1.32 (14.3%) 6.1.1.7 (14.3%)" "Acting on GTP; involved in cellular and subcellular movement (71.4%) phosphoenolpyruvate carboxykinase (GTP) (14.3%) alanine--tRNA ligase (14.3%)" "GO:0000027 (4.4%) GO:0009409 (4.4%) GO:0010467 (4.4%)" "GO:0005829 (5.3%) GO:1990904 (4.4%) GO:0005737 (2.6%)" "GO:0003677 (17.5%) GO:0000049 (5.3%) GO:0005525 (5.3%)" "ribosomal large subunit assembly (4.4%) response to cold (4.4%) gene expression (4.4%)" "cytosol (5.3%) ribonucleoprotein complex (4.4%) cytoplasm (2.6%)" "DNA binding (17.5%) tRNA binding (5.3%) GTP binding (5.3%)" "IPR001387 (8.1%) IPR010057 (8.1%) IPR010982 (8.1%)" "Cro/C1-type, helix-turn-helix domain (8.1%) HTH-type transcriptional regulator Rgg, C-terminal domain (8.1%) Lambda repressor-like, DNA-binding domain superfamily (8.1%)" AYAPSLDTWVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025396 (100%) Protein of unknown function DUF4302 (100%) VSNQMVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006813 (30%) GO:0006508 (2%) GO:0008360 (2%)" GO:0005886 (30%) "GO:0008324 (30%) GO:0009002 (2%)" "potassium ion transport (30%) proteolysis (2%) regulation of cell shape (2%)" plasma membrane (30%) "monoatomic cation transmembrane transporter activity (30%) serine-type D-Ala-D-Ala carboxypeptidase activity (2%)" "IPR006037 (24.2%) IPR006512 (24.2%) IPR050144 (24.2%)" "Regulator of K+ conductance, C-terminal (24.2%) YidE/YbjL duplication (24.2%) AAE Transporter (24.2%)" SVFYLPVNEVQCLTESLDKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23.6%) "GO:0000155 (23.6%) GO:0003700 (23.6%) GO:0043565 (23.6%)" membrane (23.6%) "phosphorelay sensor kinase activity (23.6%) DNA-binding transcription factor activity (23.6%) sequence-specific DNA binding (23.6%)" "IPR001789 (6.5%) IPR003594 (6.5%) IPR003661 (6.5%)" "Signal transduction response regulator, receiver domain (6.5%) Histidine kinase/HSP90-like ATPase domain (6.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.5%)" NYTGCEVFFPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006364 (20%) GO:0042274 (20%)" "GO:0005737 (20%) GO:0005840 (20%)" GO:0043022 (20%) "rRNA processing (20%) ribosomal small subunit biogenesis (20%)" "cytoplasm (20%) ribosome (20%)" ribosome binding (20%) "IPR002676 (17.2%) IPR011961 (17.2%) IPR056792 (17.2%)" "RimM, N-terminal (17.2%) Ribosome maturation factor RimM (17.2%) Ribosome maturation factor RimM, PRC barrel domain (17.2%)" SKSPALDSCPQR root "GO:0006412 (20.1%) GO:0032790 (0%)" "GO:0015935 (20.1%) GO:0005840 (0.1%) GO:1990904 (0%)" "GO:0003735 (20.1%) GO:0019843 (20.1%) GO:0000049 (19.4%)" "translation (20.1%) ribosome disassembly (0%)" "small ribosomal subunit (20.1%) ribosome (0.1%) ribonucleoprotein complex (0%)" "structural constituent of ribosome (20.1%) rRNA binding (20.1%) tRNA binding (19.4%)" "IPR006032 (33.2%) IPR012340 (33.2%) IPR005679 (33.1%)" "Small ribosomal subunit protein uS12 (33.2%) Nucleic acid-binding, OB-fold (33.2%) Ribosomal protein uS12, bacteria (33.1%)" LVMTEEGFGSPDVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.6%) "GO:0004553 (33.6%) GO:0030246 (32.8%)" carbohydrate metabolic process (33.6%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.6%) carbohydrate binding (32.8%)" "IPR006710 (12.9%) IPR005084 (12.6%) IPR006584 (12.6%)" "Glycoside hydrolase, family 43 (12.9%) Carbohydrate binding module family 6 (12.6%) Cellulose binding, type IV (12.6%)" LMGYDNYADYSLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR034005 (20.5%) IPR045090 (20.5%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidyl-dipeptidase DCP (20.5%) Peptidase M3A/M3B (20.5%)" FRDNVLLQSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045493 (25.1%) GO:0005576 (25.1%) "GO:0046559 (25.1%) GO:0033939 (24.6%)" xylan catabolic process (25.1%) extracellular region (25.1%) "alpha-glucuronidase activity (25.1%) xylan alpha-1,2-glucuronosidase activity (24.6%)" "IPR011099 (20.6%) IPR011100 (20.6%) IPR017853 (19.7%)" "Glycosyl hydrolase family 67, C-terminal (20.6%) Glycosyl hydrolase family 67, catalytic domain (20.6%) Glycoside hydrolase superfamily (19.7%)" DGLTLNGLTVTLANSGVTAGESLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TLLVQSSNFPLEVLYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20.1%) GO:0005737 (20.1%) "GO:0003879 (20.1%) GO:0005524 (20.1%) GO:0000287 (19.6%)" L-histidine biosynthetic process (20.1%) cytoplasm (20.1%) "ATP phosphoribosyltransferase activity (20.1%) ATP binding (20.1%) magnesium ion binding (19.6%)" "IPR001348 (14.6%) IPR013820 (14.6%) IPR011322 (14.2%)" "ATP phosphoribosyltransferase HisG (14.6%) ATP phosphoribosyltransferase, catalytic domain (14.6%) Nitrogen regulatory PII-like, alpha/beta (14.2%)" YASYEGTSSTGSMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.8 (100%) hypoxanthine phosphoribosyltransferase (100%) "GO:0006166 (10%) GO:0006178 (10%) GO:0032263 (10%)" "GO:0005829 (10%) GO:0016020 (8.7%)" "GO:0000166 (10%) GO:0000287 (10%) GO:0004422 (10%)" "purine ribonucleoside salvage (10%) guanine salvage (10%) GMP salvage (10%)" "cytosol (10%) membrane (8.7%)" "nucleotide binding (10%) magnesium ion binding (10%) hypoxanthine phosphoribosyltransferase activity (10%)" "IPR000836 (25%) IPR005904 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (25%) Hypoxanthine phosphoribosyl transferase (25%) Phosphoribosyltransferase-like (25%)" LEQLANLDHVPSKEELYELLGDFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (80%) GO:0016740 (20%)" "glycosyltransferase activity (80%) transferase activity (20%)" "IPR000836 (26.6%) IPR017932 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (26.6%) Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%)" TAYELVVLPLTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) IPR003744 (100%) Queuosine precursor transporter (100%) EELDALVAGVK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.8.1.7 (100%) cysteine desulfurase (100%) GO:0006534 (32.8%) "GO:0030170 (32.8%) GO:0031071 (32.8%) GO:0016829 (1.6%)" cysteine metabolic process (32.8%) "pyridoxal phosphate binding (32.8%) cysteine desulfurase activity (32.8%) lyase activity (1.6%)" "IPR000192 (14.4%) IPR010970 (14.4%) IPR015421 (14.4%)" "Aminotransferase class V domain (14.4%) Cysteine desulfurase, SufS (14.4%) Pyridoxal phosphate-dependent transferase, major domain (14.4%)" LCLPDRLLQFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006537 (25.8%) GO:0005829 (25.8%) "GO:0004354 (25.8%) GO:0000166 (22.6%)" glutamate biosynthetic process (25.8%) cytosol (25.8%) "glutamate dehydrogenase (NADP+) activity (25.8%) nucleotide binding (22.6%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" AATLNPTMLQNLANGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (45.8%) GO:0003746 (54.2%) cytoplasm (45.8%) translation elongation factor activity (54.2%) "IPR014039 (21%) IPR036402 (21%) IPR001816 (19.4%)" "Translation elongation factor EFTs/EF1B, dimerisation (21%) Elongation factor Ts, dimerisation domain superfamily (21%) Translation elongation factor EFTs/EF1B (19.4%)" LVMHLDKEVYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0016020 (15.4%) GO:0005886 (4.6%)" "GO:0048038 (20%) GO:0051539 (20%) GO:0016651 (15.4%)" "membrane (15.4%) plasma membrane (4.6%)" "quinone binding (20%) 4 iron, 4 sulfur cluster binding (20%) oxidoreductase activity, acting on NAD(P)H (15.4%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" SASSVVEQLLSMMGQNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016042 (50%) GO:0016787 (50%) lipid catabolic process (50%) hydrolase activity (50%) "IPR043864 (27%) IPR016035 (25.4%) IPR002641 (23.8%)" "OMP85-like, membrane spanning beta-barrel domain (27%) Acyl transferase/acyl hydrolase/lysophospholipase (25.4%) Patatin-like phospholipase domain (23.8%)" VLVEENR root "1.8.1.4 (23.2%) 6.3.2.13 (14.3%) 3.4.24.- (12.5%)" "dihydrolipoyl dehydrogenase (23.2%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (14.3%) Metalloendopeptidases (12.5%)" "GO:0009395 (6.8%) GO:0006508 (1.7%) GO:0006103 (1.4%)" "GO:0005737 (4.5%) GO:0016020 (3.9%) GO:0005886 (2.2%)" "GO:0042578 (6.6%) GO:0005524 (4.2%) GO:0046872 (1.7%)" "phospholipid catabolic process (6.8%) proteolysis (1.7%) 2-oxoglutarate metabolic process (1.4%)" "cytoplasm (4.5%) membrane (3.9%) plasma membrane (2.2%)" "phosphoric ester hydrolase activity (6.6%) ATP binding (4.2%) metal ion binding (1.7%)" "IPR007312 (5.2%) IPR017850 (5.2%) IPR027417 (2.1%)" "Phosphoesterase (5.2%) Alkaline-phosphatase-like, core domain superfamily (5.2%) P-loop containing nucleoside triphosphate hydrolase (2.1%)" MLNPFSHLQDLLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (16.7%) GO:0034605 (16.7%)" GO:0005737 (16.7%) "GO:0005524 (16.7%) GO:0008233 (16.7%) GO:0016887 (16.7%)" "proteolysis (16.7%) cellular response to heat (16.7%)" cytoplasm (16.7%) "ATP binding (16.7%) peptidase activity (16.7%) ATP hydrolysis activity (16.7%)" "IPR004176 (9.5%) IPR001943 (9.2%) IPR003593 (9.2%)" "Clp, repeat (R) N-terminal domain (9.5%) UVR domain (9.2%) AAA+ ATPase domain (9.2%)" VLPGGGEANVAVSVANYGHEAYFVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" EFLKELEFELPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) NLLLPSDR root "1.1.99.2 (25%) 2.7.13.3 (25%) 3.4.-.- (25%)" "L-2-hydroxyglutarate dehydrogenase (25%) histidine kinase (25%) Acting on peptide bonds (peptidases) (25%)" "GO:0006508 (22.5%) GO:0010468 (1.5%) GO:0006383 (1%)" "GO:0005634 (2.5%) GO:0005886 (2%) GO:0000127 (1%)" "GO:0008239 (22.5%) GO:0008236 (22%) GO:0005524 (2%)" "proteolysis (22.5%) regulation of gene expression (1.5%) transcription by RNA polymerase III (1%)" "nucleus (2.5%) plasma membrane (2%) transcription factor TFIIIC complex (1%)" "dipeptidyl-peptidase activity (22.5%) serine-type peptidase activity (22%) ATP binding (2%)" "IPR002469 (16.5%) IPR050278 (16.5%) IPR001375 (16.1%)" "Dipeptidylpeptidase IV, N-terminal domain (16.5%) Serine protease S9B/DPPIV (16.5%) Peptidase S9, prolyl oligopeptidase, catalytic domain (16.1%)" NWNLDALTDYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.8%) IPR020845 (25.8%) IPR042099 (24.2%)" "AMP-dependent synthetase/ligase domain (25.8%) AMP-binding, conserved site (25.8%) ANL, N-terminal domain (24.2%)" LNLPTVFCSGGPMEAGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.7%) GO:0009099 (16.7%)" GO:0005829 (16.7%) "GO:0000287 (16.7%) GO:0004160 (16.7%) GO:0051537 (16.7%)" "isoleucine biosynthetic process (16.7%) L-valine biosynthetic process (16.7%)" cytosol (16.7%) "magnesium ion binding (16.7%) dihydroxy-acid dehydratase activity (16.7%) 2 iron, 2 sulfur cluster binding (16.7%)" "IPR000581 (16.8%) IPR004404 (16.8%) IPR020558 (16.8%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.8%) Dihydroxy-acid dehydratase (16.8%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.8%)" LALDEAPLLLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (66.7%) GO:0016787 (33.3%) carbohydrate metabolic process (66.7%) hydrolase activity (33.3%) "IPR008928 (20%) IPR012878 (20%) IPR032275 (20%)" "Six-hairpin glycosidase superfamily (20%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (20%) Domain of unknown function DUF4986 (20%)" MKPTLLLLAAGMGSR Pseudomonadati Bacteria Pseudomonadati 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016740 (91.7%) GO:0016779 (6.9%) GO:0004355 (1.4%)" "transferase activity (91.7%) nucleotidyltransferase activity (6.9%) glutamate synthase (NADPH) activity (1.4%)" "IPR029044 (65.5%) IPR005835 (33.2%) IPR050065 (0.9%)" "Nucleotide-diphospho-sugar transferases (65.5%) Nucleotidyl transferase domain (33.2%) Bifunctional protein GlmU-like (0.9%)" GVLANAYTYLPDAFAGYTDGQFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" NTNVLAGEAGGLTQHLGAYSVTLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (25%) "GO:0003743 (25%) GO:0003924 (25%) GO:0005525 (25%)" cytoplasm (25%) "translation initiation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000178 (9%) IPR000795 (9%) IPR005225 (9%)" "Translation initiation factor IF-2, bacterial-like (9%) Translational (tr)-type GTP-binding domain (9%) Small GTP-binding domain (9%)" WGYFPSFSGAWR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (3.9%) GO:0044718 (2.6%)" GO:0009279 (88.2%) "GO:0015344 (3.9%) GO:0015288 (1.3%)" "iron ion transport (3.9%) siderophore transmembrane transport (2.6%)" cell outer membrane (88.2%) "siderophore uptake transmembrane transporter activity (3.9%) porin activity (1.3%)" "IPR023996 (13.1%) IPR039426 (13.1%) IPR012910 (12.9%)" "TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent receptor-like (13.1%) TonB-dependent receptor, plug domain (12.9%)" NYLTYNGSLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR039426 (14.8%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent receptor-like (14.8%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" FAELGLEYFYTLLDDAVAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20%) GO:0006102 (20%)" "GO:0000287 (20%) GO:0004450 (20%) GO:0051287 (20%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "magnesium ion binding (20%) isocitrate dehydrogenase (NADP+) activity (20%) NAD binding (20%)" "IPR004790 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" QLSSLYASASLGYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (11.4%) GO:0009279 (88.6%) iron ion transport (11.4%) cell outer membrane (88.6%) "IPR012910 (14.2%) IPR023996 (14.2%) IPR023997 (14.2%)" "TonB-dependent receptor, plug domain (14.2%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.2%)" VGATGLWQFMLPTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000270 (33.3%) GO:0016020 (33.3%) GO:0008933 (33.3%) peptidoglycan metabolic process (33.3%) membrane (33.3%) peptidoglycan lytic transglycosylase activity (33.3%) "IPR000189 (20.9%) IPR008258 (20.9%) IPR018392 (20.2%)" "Prokaryotic transglycosylase, active site (20.9%) Transglycosylase SLT domain 1 (20.9%) LysM domain (20.2%)" YSVNANNDKELGFANYVAPNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.6%) GO:0009279 (36.8%) GO:0015344 (31.6%) siderophore transmembrane transport (31.6%) cell outer membrane (36.8%) siderophore uptake transmembrane transporter activity (31.6%) "IPR036942 (21.9%) IPR057601 (21.9%) IPR008969 (18.8%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (21.9%) TonB-dependent transporter Oar-like, beta-barrel domain (21.9%) Carboxypeptidase-like, regulatory domain superfamily (18.8%)" DHGPLTMVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) EYGVDVLGTSVEALMNTEDRDLFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.4.16 (50.7%) 6.3.5.5 (49.3%)" "carbamoyl-phosphate synthase (ammonia) (50.7%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (49.3%)" "GO:0006541 (14.1%) GO:0006221 (13.4%) GO:0006526 (13.4%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (13.4%) L-arginine biosynthetic process (13.4%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.5%) IPR011761 (10.5%) IPR005483 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%) Carbamoyl phosphate synthase, CPSase domain (10.2%)" LMPFDEVMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR019554 (33.7%) IPR049712 (33.7%) IPR003715 (32.7%)" "Soluble ligand binding domain (33.7%) Polysaccharide export protein (33.7%) Polysaccharide export protein, N-terminal domain (32.7%)" AFLDLYPNFVEEFNQLLLPEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) GETRPMVDLQGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.3%) "GO:0004822 (14.4%) GO:0000049 (14.3%) GO:0005524 (14.3%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.3%) "isoleucine-tRNA ligase activity (14.4%) tRNA binding (14.3%) ATP binding (14.3%)" "IPR023586 (12.7%) IPR002300 (12.6%) IPR002301 (12.6%)" "Isoleucine-tRNA ligase, type 2 (12.7%) Aminoacyl-tRNA synthetase, class Ia (12.6%) Isoleucine-tRNA ligase (12.6%)" SKVSEDLEFYSVMR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (32.7%) "GO:0005525 (32.7%) GO:0043022 (32.7%) GO:0016787 (2%)" ribosome biogenesis (32.7%) "GTP binding (32.7%) ribosome binding (32.7%) hydrolase activity (2%)" "IPR005225 (14.3%) IPR006073 (14.3%) IPR015946 (14.3%)" "Small GTP-binding domain (14.3%) GTP binding domain (14.3%) K homology domain-like, alpha/beta (14.3%)" FLSQPFTVAEQFTGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (22.8%) GO:0005886 (22.2%)" "GO:0005524 (22.8%) GO:0046933 (22.8%) GO:0016787 (9.3%)" "proton-transporting ATP synthase complex (22.8%) plasma membrane (22.2%)" "ATP binding (22.8%) proton-transporting ATP synthase activity, rotational mechanism (22.8%) hydrolase activity (9.3%)" "IPR000194 (10.1%) IPR020003 (10.1%) IPR024034 (10.1%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.1%) ATPase, alpha/beta subunit, nucleotide-binding domain, active site (10.1%) ATPase, F1/V1 complex, beta/alpha subunit, C-terminal (10.1%)" WGYFPSVSAGWLVTNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.4%) IPR012910 (13.4%) IPR023996 (13.4%)" "TonB-dependent receptor-like, beta-barrel (13.4%) TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%)" ATWNLSFLPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051607 (33.3%) "GO:0003723 (33.3%) GO:0016788 (33.3%)" defense response to virus (33.3%) "RNA binding (33.3%) hydrolase activity, acting on ester bonds (33.3%)" "IPR010156 (33.3%) IPR045747 (33.3%) IPR049435 (33.3%)" "CRISPR-associated endoribonuclease Cas6 (33.3%) CRISPR-associated protein Cas6, N-terminal domain superfamily (33.3%) CRISPR associated protein Cas6, C-terminal domain (33.3%)" AELEKEVQQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.8%) "GO:0005886 (19.8%) GO:0016020 (1.2%)" "GO:0003723 (19.8%) GO:0004521 (19.8%) GO:0016787 (19.8%)" mRNA catabolic process (19.8%) "plasma membrane (19.8%) membrane (1.2%)" "RNA binding (19.8%) RNA endonuclease activity (19.8%) hydrolase activity (19.8%)" "IPR022711 (13.3%) IPR003607 (12.5%) IPR004087 (12.5%)" "Ribonuclease Y, N-terminal (13.3%) HD/PDEase domain (12.5%) K Homology domain (12.5%)" SLQTLLMGLNQALDMDNLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032276 (100%) Protein of unknown function DUF4836 (100%) VCAVGDDSQSLYSFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (14.3%) "GO:0005829 (14.3%) GO:0033202 (14.3%)" "GO:0003677 (14.3%) GO:0005524 (14.3%) GO:0043138 (14.3%)" recombinational repair (14.3%) "cytosol (14.3%) DNA helicase complex (14.3%)" "DNA binding (14.3%) ATP binding (14.3%) 3'-5' DNA helicase activity (14.3%)" "IPR000212 (20.5%) IPR014016 (20.5%) IPR014017 (20.5%)" "DNA helicase, UvrD/REP type (20.5%) UvrD-like helicase, ATP-binding domain (20.5%) UvrD-like DNA helicase, C-terminal (20.5%)" NSLESNLLLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR011204 (100%) Virulence protein RhuM-like (100%) RTTTNPAEALQGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (1.5%) GO:0009279 (97.1%) GO:0015344 (1.5%) siderophore transmembrane transport (1.5%) cell outer membrane (97.1%) siderophore uptake transmembrane transporter activity (1.5%) "IPR008969 (13%) IPR037066 (13%) IPR012910 (12.8%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain superfamily (13%) TonB-dependent receptor, plug domain (12.8%)" LDGTDYVHAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" ELGLELVR root "4.1.3.27 (60.6%) 5.3.1.14 (11.6%) 3.1.13.4 (7.4%)" "anthranilate synthase (60.6%) L-rhamnose isomerase (11.6%) poly(A)-specific ribonuclease (7.4%)" "GO:0000162 (12.3%) GO:2000142 (3.9%) GO:0034605 (3%)" "GO:0005737 (8.5%) GO:0005829 (3%) GO:0005634 (1.6%)" "GO:0016829 (11.5%) GO:0003700 (4.7%) GO:0005524 (4.4%)" "L-tryptophan biosynthetic process (12.3%) regulation of DNA-templated transcription initiation (3.9%) cellular response to heat (3%)" "cytoplasm (8.5%) cytosol (3%) nucleus (1.6%)" "lyase activity (11.5%) DNA-binding transcription factor activity (4.7%) ATP binding (4.4%)" "IPR029062 (7.2%) IPR017926 (6.6%) IPR006221 (6.5%)" "Class I glutamine amidotransferase-like (7.2%) Glutamine amidotransferase (6.6%) Anthranilate synthase/para-aminobenzoate synthase like domain (6.5%)" VYGAADNVYLWSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FYSDAVTAYYTPEKPTPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011990 (50%) IPR033985 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) SusD-like, N-terminal (50%)" FEGLWPLPNGVSYNSYLLDDEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.6.3.- (100%) With oxygen as acceptor (100%) "GO:0010181 (26.1%) GO:0009055 (24.6%) GO:0016491 (24.6%)" "FMN binding (26.1%) electron transfer activity (24.6%) oxidoreductase activity (24.6%)" "IPR045761 (17.6%) IPR001279 (17.2%) IPR008254 (16.7%)" "ODP domain (17.6%) Metallo-beta-lactamase (17.2%) Flavodoxin/nitric oxide synthase (16.7%)" PGDQTEFPRPLYGNPFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VLEGSEVGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (25%) GO:0005737 (25%) "GO:0004821 (25%) GO:0005524 (25%)" histidyl-tRNA aminoacylation (25%) cytoplasm (25%) "histidine-tRNA ligase activity (25%) ATP binding (25%)" "IPR004154 (12.8%) IPR006195 (12.8%) IPR015807 (12.8%)" "Anticodon-binding (12.8%) Aminoacyl-tRNA synthetase, class II (12.8%) Histidine-tRNA ligase (12.8%)" MEQLSPLQALLQQR Bacteria Bacteria GO:0005694 (24.8%) "GO:0005524 (24.8%) GO:0016787 (24.8%) GO:0043139 (24.8%)" chromosome (24.8%) "ATP binding (24.8%) hydrolase activity (24.8%) 5'-3' DNA helicase activity (24.8%)" "IPR003593 (16.7%) IPR041677 (16.7%) IPR041679 (16.7%)" "AAA+ ATPase domain (16.7%) DNA2/NAM7 helicase, helicase domain (16.7%) DNA2/NAM7 helicase-like, C-terminal (16.7%)" LYNLMVSADRPLLNGLDTYWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" LNLDNVGR root 6.3.2.2 (100%) glutamate--cysteine ligase (100%) "GO:0044718 (26.6%) GO:0006508 (0.6%) GO:0006750 (0.6%)" "GO:0009279 (26.6%) GO:0016020 (9.5%) GO:0009507 (0.6%)" "GO:0015344 (26.6%) GO:0004177 (4.1%) GO:0000166 (0.6%)" "siderophore transmembrane transport (26.6%) proteolysis (0.6%) glutathione biosynthetic process (0.6%)" "cell outer membrane (26.6%) membrane (9.5%) chloroplast (0.6%)" "siderophore uptake transmembrane transporter activity (26.6%) aminopeptidase activity (4.1%) nucleotide binding (0.6%)" "IPR000531 (15%) IPR012910 (15%) IPR039426 (15%)" "TonB-dependent receptor-like, beta-barrel (15%) TonB-dependent receptor, plug domain (15%) TonB-dependent receptor-like (15%)" FFGQANWGLEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033430 (34.9%) IPR032184 (32.6%) IPR033429 (32.6%)" "Domain of unknown function DUF5121 (34.9%) Domain of unknown function DUF5016 (32.6%) Domain of unknown function DUF5125 (32.6%)" KLHHSFTELYSLLFVDGNPAGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25.4%) IPR005263 (25.4%) IPR020625 (25.4%)" "DapA-like (25.4%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25.4%) Schiff base-forming aldolase, active site (25.4%)" GFLEEVQACCDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" SLPFSLQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006355 (52.6%) GO:0006351 (47.4%)" "regulation of DNA-templated transcription (52.6%) DNA-templated transcription (47.4%)" "IPR013321 (51.3%) IPR007337 (48.7%)" "Arc-type ribbon-helix-helix (51.3%) RelB antitoxin/Antitoxin DinJ (48.7%)" TTLATLLYNMFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.5%) GO:0009252 (12.5%) GO:0051301 (12.5%)" GO:0005737 (12.5%) "GO:0005524 (12.6%) GO:0000287 (12.5%) GO:0008765 (12.5%)" "regulation of cell shape (12.5%) peptidoglycan biosynthetic process (12.5%) cell division (12.5%)" cytoplasm (12.5%) "ATP binding (12.6%) magnesium ion binding (12.5%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.5%)" "IPR000713 (14.4%) IPR013221 (14.4%) IPR004101 (14.3%)" "Mur ligase, N-terminal catalytic domain (14.4%) Mur ligase, central (14.4%) Mur ligase, C-terminal (14.3%)" WEVMEVLGFNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" RTDSFNVNFFLDNLEQNQNNNATR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" AATGCEMDCTSLDNTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) TYGQYVDDVGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR050250 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Macrolide Exporter MacB (33.3%)" LTFLNSEYLTEENVAEQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (12.6%) GO:0044210 (12.6%)" "GO:0005829 (12.6%) GO:0097268 (11.9%)" "GO:0003883 (12.6%) GO:0005524 (12.6%) GO:0042802 (12.6%)" "pyrimidine nucleobase biosynthetic process (12.6%) 'de novo' CTP biosynthetic process (12.6%)" "cytosol (12.6%) cytoophidium (11.9%)" "CTP synthase activity (12.6%) ATP binding (12.6%) identical protein binding (12.6%)" "IPR004468 (17.4%) IPR017926 (17.4%) IPR017456 (16.5%)" "CTP synthase (17.4%) Glutamine amidotransferase (17.4%) CTP synthase, N-terminal (16.5%)" AVAFSLADGQLPSNAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.2%) IPR003156 (9.2%) IPR012947 (9.2%)" "Alanine-tRNA ligase, class IIc (9.2%) DHHA1 domain (9.2%) Threonyl/alanyl tRNA synthetase, SAD (9.2%)" LVGVVECNLPEEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.8.3.- (100%) CoA-transferases (100%) GO:0006083 (33.3%) "GO:0003986 (33.3%) GO:0008775 (33.3%)" acetate metabolic process (33.3%) "acetyl-CoA hydrolase activity (33.3%) acetate CoA-transferase activity (33.3%)" "IPR003702 (20.4%) IPR026888 (20.4%) IPR046433 (20.4%)" "Acetyl-CoA hydrolase/transferase, N-terminal (20.4%) Acetyl-CoA hydrolase/transferase, C-terminal domain (20.4%) Acetyl-CoA hydrolase/transferase (20.4%)" FPALSSTSNANNYNTNTLWMFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" YREDAFYELEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (12.3%) GO:0006417 (12.3%)" GO:0005737 (12.3%) "GO:0005524 (13%) GO:0016887 (12.7%) GO:0003677 (12.6%)" "translation (12.3%) regulation of translation (12.3%)" cytoplasm (12.3%) "ATP binding (13%) ATP hydrolysis activity (12.7%) DNA binding (12.6%)" "IPR051309 (12.7%) IPR003439 (12.6%) IPR003593 (12.6%)" "ABC transporter ABCF subfamily ATPase (12.7%) ABC transporter-like, ATP-binding domain (12.6%) AAA+ ATPase domain (12.6%)" NNDSDWLSNFFDDTLFNTEVMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (33.3%) IPR008978 (33.3%) IPR031107 (33.3%)" "Alpha crystallin/Hsp20 domain (33.3%) HSP20-like chaperone (33.3%) Small heat shock protein (33.3%)" LLHAFNALLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (17%) IPR004602 (17%) IPR041102 (17%)" "ABC transporter-like, ATP-binding domain (17%) UvrABC system subunit A (17%) UvrA, interaction domain (17%)" ADAGLAGLTVTPER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006865 (33.3%) GO:0043190 (33.3%) GO:0022857 (33.3%) amino acid transport (33.3%) ATP-binding cassette (ABC) transporter complex (33.3%) transmembrane transporter activity (33.3%) "IPR000515 (16.8%) IPR001638 (16.8%) IPR010065 (16.8%)" "ABC transporter type 1, transmembrane domain MetI-like (16.8%) Solute-binding protein family 3/N-terminal domain of MltF (16.8%) Amino acid ABC transporter, permease protein, 3-TM domain (16.8%)" NYYMLYAAGGVPEHLAYSMSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0005975 (31.2%) GO:0045493 (2.2%)" "GO:0030246 (33.3%) GO:0004553 (32.6%) GO:0031176 (0.7%)" "carbohydrate metabolic process (31.2%) xylan catabolic process (2.2%)" "carbohydrate binding (33.3%) hydrolase activity, hydrolyzing O-glycosyl compounds (32.6%) endo-1,4-beta-xylanase activity (0.7%)" "IPR005084 (12.9%) IPR006584 (12.9%) IPR006710 (12.9%)" "Carbohydrate binding module family 6 (12.9%) Cellulose binding, type IV (12.9%) Glycoside hydrolase, family 43 (12.9%)" VEESVAQPFGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.5%) GO:0009341 (25.5%) "GO:0004565 (25.5%) GO:0030246 (23.5%)" lactose catabolic process (25.5%) beta-galactosidase complex (25.5%) "beta-galactosidase activity (25.5%) carbohydrate binding (23.5%)" "IPR006102 (6.9%) IPR006103 (6.9%) IPR023230 (6.9%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.9%) Glycoside hydrolase family 2, catalytic domain (6.9%) Glycoside hydrolase, family 2, conserved site (6.9%)" VEFSGSYMGWNPNPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.3%) IPR002933 (33.3%) IPR011650 (33.3%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (33.3%) Peptidase M20, dimerisation domain (33.3%)" AMQLLSELEPHNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0000162 (47.7%) "GO:0046872 (47.2%) GO:0004049 (5.1%)" L-tryptophan biosynthetic process (47.7%) "metal ion binding (47.2%) anthranilate synthase activity (5.1%)" "IPR015890 (25.2%) IPR019999 (25.2%) IPR005801 (24.9%)" "Chorismate-utilising enzyme, C-terminal (25.2%) Anthranilate synthase component I-like (25.2%) ADC synthase (24.9%)" DLLPMVDK Pseudomonadati Bacteria Pseudomonadati 1.8.1.4 (100%) dihydrolipoyl dehydrogenase (100%) "GO:0006103 (1.1%) GO:0006979 (1.1%)" "GO:0016747 (47.7%) GO:0016788 (45.5%) GO:0016787 (2.3%)" "2-oxoglutarate metabolic process (1.1%) response to oxidative stress (1.1%)" "acyltransferase activity, transferring groups other than amino-acyl groups (47.7%) hydrolase activity, acting on ester bonds (45.5%) hydrolase activity (2.3%)" "IPR000801 (16.2%) IPR005181 (16.2%) IPR050583 (16.2%)" "Esterase-like (16.2%) Sialate O-acetylesterase domain (16.2%) Mycobacterial A85 antigen (16.2%)" STDQFEAFPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (2.3%) "GO:0000155 (24%) GO:0003700 (24%) GO:0005524 (24%)" membrane (2.3%) "phosphorelay sensor kinase activity (24%) DNA-binding transcription factor activity (24%) ATP binding (24%)" "IPR011110 (6.9%) IPR015943 (6.9%) IPR001789 (6.7%)" "Two component regulator propeller (6.9%) WD40/YVTN repeat-like-containing domain superfamily (6.9%) Signal transduction response regulator, receiver domain (6.7%)" LMFLFSAK Pseudomonadati Bacteria Pseudomonadati "GO:0005886 (0.8%) GO:0016020 (0.8%)" "GO:0004222 (96.1%) GO:0016787 (1.6%) GO:0022857 (0.8%)" "plasma membrane (0.8%) membrane (0.8%)" "metalloendopeptidase activity (96.1%) hydrolase activity (1.6%) transmembrane transporter activity (0.8%)" "IPR016047 (38%) IPR011055 (37.5%) IPR050570 (23.6%)" "M23ase, beta-sheet core domain (38%) Duplicated hybrid motif (37.5%) Bacterial cell wall metabolism enzyme (23.6%)" LAYNSSQLDANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (29%) GO:0044718 (6.5%)" GO:0009279 (58.1%) GO:0015344 (6.5%) "iron ion transport (29%) siderophore transmembrane transport (6.5%)" cell outer membrane (58.1%) siderophore uptake transmembrane transporter activity (6.5%) "IPR011662 (12.6%) IPR012910 (11.9%) IPR023996 (11.9%)" "Secretin/TonB, short N-terminal domain (12.6%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" EEKLELFLPNGPR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0045900 (12.6%) GO:0006412 (12.5%)" GO:0005737 (12.5%) "GO:0005524 (12.7%) GO:0016887 (12.6%) GO:0000049 (12.6%)" "negative regulation of translational elongation (12.6%) translation (12.5%)" cytoplasm (12.5%) "ATP binding (12.7%) ATP hydrolysis activity (12.6%) tRNA binding (12.6%)" "IPR003439 (16.7%) IPR022374 (16.7%) IPR027417 (16.7%)" "ABC transporter-like, ATP-binding domain (16.7%) Energy-dependent translational throttle protein EttA (16.7%) P-loop containing nucleoside triphosphate hydrolase (16.7%)" FADPVNPR Bacteria Bacteria 2.3.-.- (100%) Acyltransferases (100%) "GO:0005975 (14.3%) GO:0006826 (14.3%)" GO:0005737 (14.3%) "GO:0016787 (28.6%) GO:0005506 (14.3%) GO:0008849 (14.3%)" "carbohydrate metabolic process (14.3%) iron ion transport (14.3%)" cytoplasm (14.3%) "hydrolase activity (28.6%) iron ion binding (14.3%) enterochelin esterase activity (14.3%)" "IPR013783 (24.4%) IPR003790 (23.2%) IPR017853 (23.2%)" "Immunoglobulin-like fold (24.4%) Glycosyl hydrolase-like 10 (23.2%) Glycoside hydrolase superfamily (23.2%)" VVSLSVPDK root "5.1.3.3 (92.3%) 2.7.7.- (3.8%) 5.1.3.- (3.8%)" "aldose 1-epimerase (92.3%) Nucleotidyltransferases (3.8%) Acting on carbohydrates and derivatives (3.8%)" "GO:0006006 (17.9%) GO:0033499 (17.9%) GO:0002376 (1.4%)" "GO:0005737 (17.9%) GO:0005576 (1.4%) GO:0016020 (1.4%)" "GO:0004034 (17.9%) GO:0030246 (16.6%) GO:0004252 (1.4%)" "glucose metabolic process (17.9%) galactose catabolic process via UDP-galactose, Leloir pathway (17.9%) immune system process (1.4%)" "cytoplasm (17.9%) extracellular region (1.4%) membrane (1.4%)" "aldose 1-epimerase activity (17.9%) carbohydrate binding (16.6%) serine-type endopeptidase activity (1.4%)" "IPR008183 (14.1%) IPR047215 (14.1%) IPR011013 (13%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (14.1%) Galactose mutarotase-like (14.1%) Galactose mutarotase-like domain superfamily (13%)" MFDVVTDPLMGTLADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008643 (25.3%) GO:0006814 (24.1%)" GO:0005886 (25.3%) GO:0015293 (25.3%) "carbohydrate transport (25.3%) sodium ion transport (24.1%)" plasma membrane (25.3%) symporter activity (25.3%) "IPR039672 (34.9%) IPR001927 (33.3%) IPR036259 (31.7%)" "Lactose permease-like (34.9%) Sodium:galactoside symporter (33.3%) MFS transporter superfamily (31.7%)" LLHVFNSADGLSYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0008360 (50%) GO:0005886 (50%) regulation of cell shape (50%) plasma membrane (50%) "IPR007221 (26.4%) IPR055342 (26.4%) IPR042175 (23.6%)" "Rod shape-determining protein MreC (26.4%) Rod shape-determining protein MreC, beta-barrel core (26.4%) Cell/Rod shape-determining protein MreC, domain 2 (23.6%)" LSGSVDYYHNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" CGFLGLLHMELVQER root "3.6.5.0 (98.1%) 3.6.5.- (1.5%) 3.6.5.3 (0.1%)" "Unknown (98.1%) Acting on GTP; involved in cellular and subcellular movement (1.5%) protein-synthesizing GTPase (0.1%)" "GO:0045727 (15.8%) GO:0006412 (4%) GO:0009401 (0%)" "GO:0005886 (11.5%) GO:0009507 (2%) GO:0005743 (1.3%)" "GO:0005525 (15.8%) GO:0043022 (15.6%) GO:0003924 (14.6%)" "positive regulation of translation (15.8%) translation (4%) phosphoenolpyruvate-dependent sugar phosphotransferase system (0%)" "plasma membrane (11.5%) chloroplast (2%) mitochondrial inner membrane (1.3%)" "GTP binding (15.8%) ribosome binding (15.6%) GTPase activity (14.6%)" "IPR006297 (8.9%) IPR035647 (8.9%) IPR000640 (8.7%)" "Elongation factor 4 (8.9%) EF-G domain III/V-like (8.9%) Elongation factor EFG, domain V-like (8.7%)" HFNPTFHFLAPK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (16.7%) GO:0006520 (16.7%) GO:0044205 (16.7%)" GO:0005829 (16.7%) "GO:0004070 (16.7%) GO:0016597 (16.7%)" "'de novo' pyrimidine nucleobase biosynthetic process (16.7%) amino acid metabolic process (16.7%) 'de novo' UMP biosynthetic process (16.7%)" cytosol (16.7%) "aspartate carbamoyltransferase activity (16.7%) amino acid binding (16.7%)" "IPR002082 (20.1%) IPR006130 (20.1%) IPR006131 (20.1%)" "Aspartate carbamoyltransferase (20.1%) Aspartate/ornithine carbamoyltransferase (20.1%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.1%)" EYNTVDMSR root 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (33.5%) GO:0005975 (1%)" GO:0042597 (30.5%) GO:0008422 (35%) "glucan catabolic process (33.5%) carbohydrate metabolic process (1%)" periplasmic space (30.5%) beta-glucosidase activity (35%) "IPR001764 (11.6%) IPR017853 (11.3%) IPR036962 (11.3%)" "Glycoside hydrolase, family 3, N-terminal (11.6%) Glycoside hydrolase superfamily (11.3%) Glycoside hydrolase, family 3, N-terminal domain superfamily (11.3%)" NLVGLLQPTSGEVLYDDRDFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (29.2%) IPR017871 (25%) IPR027417 (25%)" "ABC transporter-like, ATP-binding domain (29.2%) ABC transporter-like, conserved site (25%) P-loop containing nucleoside triphosphate hydrolase (25%)" ENGHSPSEAFNETVEELTQSLGPLFGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21.2%) GO:0009099 (21.2%)" "GO:0004455 (21.2%) GO:0046872 (21.2%) GO:0016853 (15.2%)" "isoleucine biosynthetic process (21.2%) L-valine biosynthetic process (21.2%)" "ketol-acid reductoisomerase activity (21.2%) metal ion binding (21.2%) isomerase activity (15.2%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" KLLGDDEHGWDDNGVFNFEGGCYAK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.6%) GO:0005829 (17.6%) "GO:0004612 (17.6%) GO:0005524 (17.6%) GO:0046872 (17.6%)" gluconeogenesis (17.6%) cytosol (17.6%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.6%) ATP binding (17.6%) metal ion binding (17.6%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" TVVLHGVMDTPNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000272 (50%) GO:0004553 (50%) polysaccharide catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001547 (49.2%) IPR017853 (47.6%) IPR016130 (3.2%)" "Glycoside hydrolase, family 5 (49.2%) Glycoside hydrolase superfamily (47.6%) Protein-tyrosine phosphatase, active site (3.2%)" VLMLPSVR root 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006270 (11.1%) GO:0009306 (11.1%) GO:0006260 (3.7%)" "GO:0005658 (11.1%) GO:0005886 (11.1%) GO:0016020 (7.4%)" "GO:0003677 (11.1%) GO:0003887 (3.7%) GO:0005524 (3.7%)" "DNA replication initiation (11.1%) protein secretion (11.1%) DNA replication (3.7%)" "alpha DNA polymerase:primase complex (11.1%) plasma membrane (11.1%) membrane (7.4%)" "DNA binding (11.1%) DNA-directed DNA polymerase activity (3.7%) ATP binding (3.7%)" "IPR029492 (39.7%) IPR001992 (5.2%) IPR003004 (5.2%)" "Domain of unknown function DUF4435 (39.7%) T2SS_GspF/T4SS_PilC conserved site (5.2%) GspF/PilC family (5.2%)" VYGGEELYLTPLCR YASNPMDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.5%) IPR021120 (20.5%) IPR011051 (19.7%)" "5-keto 4-deoxyuronate isomerase (20.5%) KduI/IolB isomerase (20.5%) RmlC-like cupin domain superfamily (19.7%)" EGDLLPFDKEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" KPEDVLVVMSTLHSVSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.3%) GO:0009252 (12.3%) GO:0051301 (12.3%)" GO:0005737 (12.3%) "GO:0005524 (13%) GO:0000287 (12.3%) GO:0008765 (12.3%)" "regulation of cell shape (12.3%) peptidoglycan biosynthetic process (12.3%) cell division (12.3%)" cytoplasm (12.3%) "ATP binding (13%) magnesium ion binding (12.3%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.3%)" "IPR004101 (14.6%) IPR013221 (14.6%) IPR036565 (14.6%)" "Mur ligase, C-terminal (14.6%) Mur ligase, central (14.6%) Mur-like, catalytic domain superfamily (14.6%)" EELESYGLHFLDDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" STLPVGYTESLR Bacteria Bacteria 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (28%) GO:0006065 (13.7%)" "GO:0051287 (29.1%) GO:0003979 (28%) GO:0016616 (1.1%)" "polysaccharide biosynthetic process (28%) UDP-glucuronate biosynthetic process (13.7%)" "NAD binding (29.1%) UDP-glucose 6-dehydrogenase activity (28%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (1.1%)" "IPR001732 (11.3%) IPR014026 (11.3%) IPR008927 (11.1%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.3%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.3%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (11.1%)" SKYEYQTEEGEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (50.6%) IPR023614 (49.4%)" "Phosphate-selective porin O/P (50.6%) Porin domain superfamily (49.4%)" DALQTYVDGEWLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) "GO:0005829 (25%) GO:0016020 (0.4%)" "GO:0070573 (25%) GO:0046872 (24.6%)" proteolysis (25%) "cytosol (25%) membrane (0.4%)" "metallodipeptidase activity (25%) metal ion binding (24.6%)" "IPR001160 (35.1%) IPR002933 (34.5%) IPR011650 (30.4%)" "Peptidase M20C, Xaa-His dipeptidase (35.1%) Peptidase M20 (34.5%) Peptidase M20, dimerisation domain (30.4%)" DDKVTDPSWTSLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" HGWTTVVLE Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (16.4%) GO:0009098 (16.4%) GO:0009099 (16.4%)" "GO:0004084 (17.3%) GO:0052654 (6.4%) GO:0052655 (6.4%)" "isoleucine biosynthetic process (16.4%) L-leucine biosynthetic process (16.4%) L-valine biosynthetic process (16.4%)" "branched-chain-amino-acid transaminase activity (17.3%) L-leucine-2-oxoglutarate transaminase activity (6.4%) L-valine-2-oxoglutarate transaminase activity (6.4%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" LLLFVTGMQNLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.22 (100%) asparagine--tRNA ligase (100%) "GO:0006421 (20%) GO:0006418 (0.2%)" GO:0005737 (19.7%) "GO:0005524 (20.2%) GO:0003676 (19.8%) GO:0004816 (19.8%)" "asparaginyl-tRNA aminoacylation (20%) tRNA aminoacylation for protein translation (0.2%)" cytoplasm (19.7%) "ATP binding (20.2%) nucleic acid binding (19.8%) asparagine-tRNA ligase activity (19.8%)" "IPR004364 (14.5%) IPR006195 (14.3%) IPR045864 (14.3%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (14.5%) Aminoacyl-tRNA synthetase, class II (14.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.3%)" DLVHWEHLDPALAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.80 (100%) fructan beta-fructosidase (100%) GO:0005987 (32.8%) "GO:0005737 (32.8%) GO:0016020 (0.4%)" "GO:0004575 (32.8%) GO:0051669 (1.3%)" sucrose catabolic process (32.8%) "cytoplasm (32.8%) membrane (0.4%)" "sucrose alpha-glucosidase activity (32.8%) fructan beta-fructosidase activity (1.3%)" "IPR001362 (15.6%) IPR013148 (15.6%) IPR032313 (15.6%)" "Glycoside hydrolase, family 32 (15.6%) Glycosyl hydrolase family 32, N-terminal (15.6%) Domain of unknown function DUF4980 (15.6%)" TSEFLWQEGHTAHATKEEAEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.4%) IPR004154 (11.4%) IPR004499 (11.4%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.4%) Anticodon-binding (11.4%) Proline-tRNA ligase, class IIa, archaeal-type (11.4%)" FLLSDTQTLLNSLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (16.5%) GO:0005829 (16.5%) "GO:0003677 (16.5%) GO:0005524 (16.5%) GO:0043138 (16.5%)" recombinational repair (16.5%) cytosol (16.5%) "DNA binding (16.5%) ATP binding (16.5%) 3'-5' DNA helicase activity (16.5%)" "IPR000212 (20.3%) IPR014016 (20.3%) IPR014017 (20.3%)" "DNA helicase, UvrD/REP type (20.3%) UvrD-like helicase, ATP-binding domain (20.3%) UvrD-like DNA helicase, C-terminal (20.3%)" FWDEPLTMPEDVVPATNLYDMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (25%) GO:0071555 (25%)" "GO:0016758 (25%) GO:0016798 (25%)" "carbohydrate metabolic process (25%) cell wall organization (25%)" "hexosyltransferase activity (25%) hydrolase activity, acting on glycosyl bonds (25%)" "IPR007184 (33.9%) IPR028583 (33.9%) IPR023296 (32.2%)" "Mannoside phosphorylase (33.9%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (33.9%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.2%)" GHLLELCR root "2.7.9.3 (86.6%) 4.2.1.8 (13.4%)" "selenide, water dikinase (86.6%) mannonate dehydratase (13.4%)" "GO:0016260 (16.6%) GO:0042840 (3.7%) GO:0000902 (0.4%)" "GO:0005737 (16.6%) GO:0005938 (0.4%) GO:0030427 (0.4%)" "GO:0004756 (16.6%) GO:0005524 (16.6%) GO:0000287 (16.1%)" "selenocysteine biosynthetic process (16.6%) D-glucuronate catabolic process (3.7%) cell morphogenesis (0.4%)" "cytoplasm (16.6%) cell cortex (0.4%) site of polarized growth (0.4%)" "selenide, water dikinase activity (16.6%) ATP binding (16.6%) magnesium ion binding (16.1%)" "IPR004536 (14.6%) IPR010918 (14.6%) IPR016188 (14.4%)" "Selenophosphate synthetase (14.6%) PurM-like, C-terminal domain (14.6%) PurM-like, N-terminal domain (14.4%)" ELLYAYR root "3.1.3.11 (83.5%) 4.2.3.1 (6.8%) 2.3.2.27 (2.3%)" "fructose-bisphosphatase (83.5%) threonine synthase (6.8%) RING-type E3 ubiquitin transferase (2.3%)" "GO:0006094 (23%) GO:0006565 (1.4%) GO:0006567 (1.4%)" "GO:0016020 (1.4%) GO:0005634 (1.2%) GO:0005737 (0.8%)" "GO:0042132 (23%) GO:0008270 (1.6%) GO:0030170 (1.6%)" "gluconeogenesis (23%) L-serine catabolic process (1.4%) L-threonine catabolic process (1.4%)" "membrane (1.4%) nucleus (1.2%) cytoplasm (0.8%)" "fructose 1,6-bisphosphate 1-phosphatase activity (23%) zinc ion binding (1.6%) pyridoxal phosphate binding (1.6%)" "IPR009164 (18.8%) IPR029052 (18.3%) IPR000634 (1.5%)" "Fructose-1,6-bisphosphatase class 3 (18.8%) Metallo-dependent phosphatase-like (18.3%) Serine/threonine dehydratase, pyridoxal-phosphate-binding site (1.5%)" GKNEDLFQYNTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.- (66.7%) 3.2.1.177 (33.3%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (66.7%) alpha-D-xyloside xylohydrolase (33.3%)" GO:0005975 (33.7%) "GO:0004553 (33.1%) GO:0030246 (32.6%) GO:0061634 (0.6%)" carbohydrate metabolic process (33.7%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.1%) carbohydrate binding (32.6%) alpha-D-xyloside xylohydrolase (0.6%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" LTQANLQFLADYYLMGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR024214 (100%) Protein of unknown function DUF3843 (100%) ADKEELFALAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" SLLYSVFR root "2.7.13.3 (95.7%) 1.1.1.49 (2.1%) 7.-.-.- (2.1%)" "histidine kinase (95.7%) glucose-6-phosphate dehydrogenase (NADP(+)) (2.1%) Translocases (2.1%)" "GO:0016036 (11.3%) GO:0006874 (8.1%) GO:0000076 (0.5%)" "GO:0005886 (12.3%) GO:0016020 (5%) GO:0005789 (3.8%)" "GO:0000155 (11.3%) GO:0004721 (11.3%) GO:0005524 (10.6%)" "cellular response to phosphate starvation (11.3%) intracellular calcium ion homeostasis (8.1%) DNA replication checkpoint signaling (0.5%)" "plasma membrane (12.3%) membrane (5%) endoplasmic reticulum membrane (3.8%)" "phosphorelay sensor kinase activity (11.3%) phosphoprotein phosphatase activity (11.3%) ATP binding (10.6%)" "IPR003594 (8.6%) IPR003661 (8.6%) IPR005467 (8.6%)" "Histidine kinase/HSP90-like ATPase domain (8.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (8.6%) Histidine kinase domain (8.6%)" ALSLFVQPPSVEELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.7.4.8 (95%) 2.7.-.- (5%)" "guanylate kinase (95%) Transferring phosphorus-containing groups (5%)" GO:0005829 (33.9%) "GO:0004385 (33.9%) GO:0005524 (32.1%)" cytosol (33.9%) "GMP kinase activity (33.9%) ATP binding (32.1%)" "IPR008144 (20.7%) IPR008145 (20.7%) IPR017665 (19.6%)" "Guanylate kinase-like domain (20.7%) Guanylate kinase/L-type calcium channel beta subunit (20.7%) Guanylate kinase (19.6%)" LNYGVDYCDAGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.1 (80%) 3.2.1.135 (20%)" "alpha-amylase (80%) neopullulanase (20%)" "GO:0009313 (17.7%) GO:0043039 (15.8%)" "GO:0004556 (17.7%) GO:0004812 (15.8%) GO:0005524 (15.8%)" "oligosaccharide catabolic process (17.7%) tRNA aminoacylation (15.8%)" "alpha-amylase activity (17.7%) aminoacyl-tRNA ligase activity (15.8%) ATP binding (15.8%)" "IPR006047 (24.8%) IPR017853 (24.1%) IPR012947 (22.2%)" "Glycosyl hydrolase family 13, catalytic domain (24.8%) Glycoside hydrolase superfamily (24.1%) Threonyl/alanyl tRNA synthetase, SAD (22.2%)" FPLYNAEYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR032574 (100%) Protein of unknown function DUF4924 (100%) VQDTFYGLVLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LQYAENLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (28.8%) "GO:0003700 (35.6%) GO:0043565 (35.6%)" membrane (28.8%) "DNA-binding transcription factor activity (35.6%) sequence-specific DNA binding (35.6%)" "IPR018060 (47.7%) IPR009057 (43.2%) IPR020449 (9.1%)" "AraC-like, DNA binding HTH domain (47.7%) Homedomain-like superfamily (43.2%) Transcription regulator HTH, AraC- type, HTH domain (9.1%)" MLQDLAVK root "6.3.4.16 (50.6%) 6.3.5.5 (49.4%)" "carbamoyl-phosphate synthase (ammonia) (50.6%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (49.4%)" "GO:0006541 (13.5%) GO:0006221 (12.8%) GO:0006526 (12.8%)" GO:0005737 (13.5%) "GO:0004088 (13.5%) GO:0005524 (13.5%) GO:0046872 (13.5%)" "glutamine metabolic process (13.5%) pyrimidine nucleotide biosynthetic process (12.8%) L-arginine biosynthetic process (12.8%)" cytoplasm (13.5%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.5%) ATP binding (13.5%) metal ion binding (13.5%)" "IPR005479 (9.9%) IPR011761 (9.9%) IPR005483 (9.6%)" "Carbamoyl phosphate synthase, ATP-binding domain (9.9%) ATP-grasp fold (9.9%) Carbamoyl phosphate synthase, CPSase domain (9.6%)" QHGWDGEWFLR root 2.4.1.20 (100%) cellobiose phosphorylase (100%) GO:0005975 (33.1%) "GO:0016757 (32.4%) GO:0030246 (32.4%) GO:0016740 (1.4%)" carbohydrate metabolic process (33.1%) "glycosyltransferase activity (32.4%) carbohydrate binding (32.4%) transferase activity (1.4%)" "IPR033432 (12.8%) IPR052047 (12.8%) IPR010383 (12.6%)" "Glycosyl hydrolase 94, catalytic domain (12.8%) Glycosyl Hydrolase 94 Enzymes (12.8%) Glycosyl hydrolase 94, supersandwich domain (12.6%)" SEDVSLLSGSGLSSYSVVVGSFSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (11.1%) GO:0042834 (88.9%) cell division (11.1%) peptidoglycan binding (88.9%) "IPR007730 (50%) IPR036680 (50%)" "Sporulation-like domain (50%) Sporulation-like domain superfamily (50%)" MLVADTDLGCELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (51.1%) IPR029052 (48.9%)" "Fructose-1,6-bisphosphatase class 3 (51.1%) Metallo-dependent phosphatase-like (48.9%)" GLWALALANTGER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006857 (33.3%) GO:0005886 (33.3%) GO:1904680 (33.3%) oligopeptide transport (33.3%) plasma membrane (33.3%) peptide transmembrane transporter activity (33.3%) "IPR000109 (16.7%) IPR005279 (16.7%) IPR018456 (16.7%)" "Proton-dependent oligopeptide transporter family (16.7%) Dipeptide/tripeptide permease (16.7%) PTR2 family proton/oligopeptide symporter, conserved site (16.7%)" NPNAAPTDFMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.8%) IPR011990 (47.2%)" "Tetratricopeptide repeat (52.8%) Tetratricopeptide-like helical domain superfamily (47.2%)" PLEHGADLVVHSATK root "2.5.1.49 (59.3%) 2.5.1.47 (16.4%) 4.4.1.11 (11.5%)" "O-acetylhomoserine aminocarboxypropyltransferase (59.3%) cysteine synthase (16.4%) methionine gamma-lyase (11.5%)" "GO:0019346 (14%) GO:0071269 (13.4%) GO:0006535 (13.4%)" "GO:0005737 (13.9%) GO:0016020 (0.1%) GO:0005886 (0%)" "GO:0030170 (14%) GO:0004124 (13.4%) GO:0003961 (13.3%)" "transsulfuration (14%) L-homocysteine biosynthetic process (13.4%) cysteine biosynthetic process from serine (13.4%)" "cytoplasm (13.9%) membrane (0.1%) plasma membrane (0%)" "pyridoxal phosphate binding (14%) cysteine synthase activity (13.4%) O-acetylhomoserine aminocarboxypropyltransferase activity (13.3%)" "IPR000277 (16.8%) IPR015421 (16.7%) IPR015424 (16.7%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (16.8%) Pyridoxal phosphate-dependent transferase, major domain (16.7%) Pyridoxal phosphate-dependent transferase (16.7%)" FYLDKTEYVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (36.7%) IPR012547 (33.3%) IPR027417 (30%)" "AAA-ATPase-like domain (36.7%) PD-(D/E)XK nuclease superfamily 9 (33.3%) P-loop containing nucleoside triphosphate hydrolase (30%)" KNEDLSLQDLLDALAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR000600 (21.2%) IPR043129 (20.2%) IPR049874 (20.2%)" "ROK family (21.2%) ATPase, nucleotide binding domain (20.2%) ROK, conserved site (20.2%)" GALTEQYVLQQLLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR025420 (33.3%) IPR027417 (33.3%) IPR041682 (33.3%)" "Domain of unknown function DUF4143 (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) AAA domain, group 14 (33.3%)" LAFYGSPMNLELSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR046335 (25.9%) IPR000843 (25%) IPR028082 (25%)" "Transcriptional regulator LacI/GalR-like, sensor domain (25.9%) LacI-type HTH domain (25%) Periplasmic binding protein-like I (25%)" HQVPELDVLTPLLFGGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR050250 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Macrolide Exporter MacB (33.3%)" LMLMENEPLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) LMLPSMLLQLPVENALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0000155 (50%) membrane (50%) phosphorelay sensor kinase activity (50%) "IPR010559 (24.2%) IPR050640 (24.2%) IPR036890 (22%)" "Signal transduction histidine kinase, internal region (24.2%) Bacterial two-component sensor kinase systems (24.2%) Histidine kinase/HSP90-like ATPase superfamily (22%)" LQATNLMLLYADK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" WVAADPDFVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (24%) GO:0006508 (2%)" GO:0005737 (24%) "GO:0005506 (24%) GO:0016747 (14%) GO:0061711 (10%)" "tRNA threonylcarbamoyladenosine modification (24%) proteolysis (2%)" cytoplasm (24%) "iron ion binding (24%) acyltransferase activity, transferring groups other than amino-acyl groups (14%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (10%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" MQLDEETEYNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR031965 (50%)" "Immunoglobulin-like fold (50%) Starch-binding module 26 (50%)" ADGVTAWLVPGSWLVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.3%) IPR004430 (14.3%) IPR015931 (14.3%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.3%) 3-isopropylmalate dehydratase, large subunit (14.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (14.3%)" KAPGVLYR root "7.1.2.2 (99.3%) 3.6.3.14 (0.7%)" "H(+)-transporting two-sector ATPase (99.3%) Transferred entry: 7.1.2.2 (0.7%)" GO:0015986 (0%) "GO:0045259 (19.2%) GO:0005886 (18.8%) GO:0005739 (0%)" "GO:0005524 (19.2%) GO:0043531 (19.2%) GO:0046933 (19.2%)" proton motive force-driven ATP synthesis (0%) "proton-transporting ATP synthase complex (19.2%) plasma membrane (18.8%) mitochondrion (0%)" "ATP binding (19.2%) ADP binding (19.2%) proton-transporting ATP synthase activity, rotational mechanism (19.2%)" "IPR000194 (10%) IPR004100 (10%) IPR005294 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%) ATP synthase, F1 complex, alpha subunit (10%)" PSEYWWLHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.-.-.- (100%) Hydrolases (100%) GO:0005975 (33.3%) GO:0016020 (33.3%) GO:0016810 (33.3%) carbohydrate metabolic process (33.3%) membrane (33.3%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (33.3%) "IPR002509 (33.3%) IPR011330 (33.3%) IPR050248 (33.3%)" "NodB homology domain (33.3%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (33.3%) Polysaccharide deacetylase, ArnD subfamily (33.3%)" DPGYFTWVLGSDFTNNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045004 (25%) GO:0005829 (23.8%) "GO:0003676 (25%) GO:0008408 (25%) GO:0004527 (1.2%)" DNA replication proofreading (25%) cytosol (23.8%) "nucleic acid binding (25%) 3'-5' exonuclease activity (25%) exonuclease activity (1.2%)" "IPR046768 (25.9%) IPR012337 (24.7%) IPR013520 (24.7%)" "Exodeoxyribonuclease X-like, C-terminal (25.9%) Ribonuclease H-like superfamily (24.7%) Ribonuclease H-like domain (24.7%)" FAADYER root "1.4.1.13 (81.5%) 1.4.1.14 (7.4%) 7.-.-.- (2.5%)" "glutamate synthase (NADPH) (81.5%) glutamate synthase (NADH) (7.4%) Translocases (2.5%)" "GO:0022900 (0.4%) GO:0005975 (0.2%) GO:0006629 (0.2%)" "GO:0016020 (1.5%) GO:0005886 (0.5%) GO:0005829 (0.3%)" "GO:0051536 (44%) GO:0016491 (34.4%) GO:0004355 (9.6%)" "electron transport chain (0.4%) carbohydrate metabolic process (0.2%) lipid metabolic process (0.2%)" "membrane (1.5%) plasma membrane (0.5%) cytosol (0.3%)" "iron-sulfur cluster binding (44%) oxidoreductase activity (34.4%) glutamate synthase (NADPH) activity (9.6%)" "IPR009051 (11.5%) IPR028261 (11.5%) IPR036188 (11.5%)" "Alpha-helical ferredoxin (11.5%) Dihydroprymidine dehydrogenase domain II (11.5%) FAD/NAD(P)-binding domain superfamily (11.5%)" KHPDLCAYLLYADEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.180 (100%) FAD:protein FMN transferase (100%) GO:0016020 (33.3%) "GO:0016740 (34.9%) GO:0046872 (31.7%)" membrane (33.3%) "transferase activity (34.9%) metal ion binding (31.7%)" "IPR024932 (52.4%) IPR003374 (47.6%)" "Flavin transferase ApbE (52.4%) ApbE-like superfamily (47.6%)" VLQDGEELNAPATVHQLAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) ANLEDVYDYLLMTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR033985 (33.8%) IPR012944 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) SusD-like, N-terminal (33.8%) RagB/SusD domain (32.4%)" DVNHDYVQQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001296 (34.1%) IPR028098 (34.1%) IPR050194 (31.7%)" "Glycosyl transferase, family 1 (34.1%) Glycosyltransferase subfamily 4-like, N-terminal domain (34.1%) Glycosyltransferase group 1 (31.7%)" NAYYYQSADGTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.8%) IPR012910 (13.8%) IPR037066 (13.8%)" "Carboxypeptidase-like, regulatory domain superfamily (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent receptor, plug domain superfamily (13.8%)" VVLWGTGKPLR root 1.1.1.271 (100%) GDP-L-fucose synthase (100%) GO:0042351 (24.7%) GO:0016020 (0.6%) "GO:0050577 (25.3%) GO:0016853 (24.7%) GO:0070401 (24.7%)" 'de novo' GDP-L-fucose biosynthetic process (24.7%) membrane (0.6%) "GDP-L-fucose synthase activity (25.3%) isomerase activity (24.7%) NADP+ binding (24.7%)" "IPR001509 (33.6%) IPR036291 (33.6%) IPR028614 (32.8%)" "NAD-dependent epimerase/dehydratase (33.6%) NAD(P)-binding domain superfamily (33.6%) GDP-L-fucose synthase/GDP-L-colitose synthase (32.8%)" LRGVLSGTLNQTLGETYSNVLTLPSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" TLLAGSQGFSPTSTEYGFWYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR024361 (50%)" "Immunoglobulin-like fold (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" ELDLYLAK root "4.3.2.1 (91.8%) 1.4.4.2 (4.1%) 3.5.4.5 (2%)" "argininosuccinate lyase (91.8%) glycine dehydrogenase (aminomethyl-transferring) (4.1%) cytidine deaminase (2%)" "GO:0042450 (17.4%) GO:0006890 (3%) GO:0015031 (3%)" "GO:0005829 (17.4%) GO:0005794 (2.5%) GO:0005886 (2.5%)" "GO:0004056 (17.4%) GO:0000149 (2.5%) GO:0003677 (2.5%)" "L-arginine biosynthetic process via ornithine (17.4%) retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (3%) protein transport (3%)" "cytosol (17.4%) Golgi apparatus (2.5%) plasma membrane (2.5%)" "argininosuccinate lyase activity (17.4%) SNARE binding (2.5%) DNA binding (2.5%)" "IPR009049 (11%) IPR022761 (11%) IPR000362 (10.7%)" "Argininosuccinate lyase (11%) Fumarate lyase, N-terminal (11%) Fumarate lyase family (10.7%)" FLVVVPSLALR root "3.1.21.5 (93.8%) 3.-.-.- (6.3%)" "type III site-specific deoxyribonuclease (93.8%) Hydrolases (6.3%)" "GO:0005829 (9.2%) GO:0005737 (1.2%)" "GO:0003677 (27.4%) GO:0005524 (27.4%) GO:0015668 (26%)" "cytosol (9.2%) cytoplasm (1.2%)" "DNA binding (27.4%) ATP binding (27.4%) type III site-specific deoxyribonuclease activity (26%)" "IPR006935 (29.2%) IPR027417 (29.2%) IPR045572 (27.6%)" "Helicase/UvrB, N-terminal (29.2%) P-loop containing nucleoside triphosphate hydrolase (29.2%) Type III restriction enzyme, C-terminal endonuclease domain (27.6%)" ELLQVSR root "4.3.1.3 (15.2%) 1.17.4.1 (9.8%) 3.1.4.52 (9.8%)" "histidine ammonia-lyase (15.2%) ribonucleoside-diphosphate reductase (9.8%) cyclic-guanylate-specific phosphodiesterase (9.8%)" "GO:0006260 (13.8%) GO:0045893 (12.1%) GO:0000122 (1.2%)" "GO:0005634 (13.7%) GO:0005654 (1.2%) GO:0001650 (1.1%)" "GO:0000978 (12.7%) GO:0000981 (11.6%) GO:0003677 (3.1%)" "DNA replication (13.8%) positive regulation of DNA-templated transcription (12.1%) negative regulation of transcription by RNA polymerase II (1.2%)" "nucleus (13.7%) nucleoplasm (1.2%) fibrillar center (1.1%)" "RNA polymerase II cis-regulatory region sequence-specific DNA binding (12.7%) DNA-binding transcription factor activity, RNA polymerase II-specific (11.6%) DNA binding (3.1%)" "IPR000647 (13.2%) IPR020604 (12.7%) IPR003619 (12.6%)" "CTF transcription factor/nuclear factor 1 (13.2%) CTF transcription factor/nuclear factor 1, DNA-binding domain (12.7%) MAD homology 1, Dwarfin-type (12.6%)" TFLPLDLSTEALGVDNDRDLTSNVATAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0042777 (20%) "GO:0005886 (20%) GO:0045259 (20%)" "GO:0005524 (20%) GO:0046933 (20%)" proton motive force-driven plasma membrane ATP synthesis (20%) "plasma membrane (20%) proton-transporting ATP synthase complex (20%)" "ATP binding (20%) proton-transporting ATP synthase activity, rotational mechanism (20%)" "IPR000131 (52.4%) IPR035968 (47.6%)" "ATP synthase, F1 complex, gamma subunit (52.4%) ATP synthase, F1 complex, gamma subunit superfamily (47.6%)" KLLADVTGR Bacteria Bacteria "GO:0005975 (46%) GO:0045493 (2%)" GO:0005886 (2%) "GO:0016787 (48%) GO:0046559 (2%)" "carbohydrate metabolic process (46%) xylan catabolic process (2%)" plasma membrane (2%) "hydrolase activity (48%) alpha-glucuronidase activity (2%)" "IPR029018 (23.1%) IPR031924 (23.1%) IPR041437 (23.1%)" "Beta-hexosaminidase-like, domain 2 (23.1%) Glycosyl hydrolase family 115 (23.1%) Gylcosyl hydrolase 115 C-terminal domain (23.1%)" NDVLALAQTGTGK Pseudomonadati Bacteria Pseudomonadati "3.6.4.13 (92.1%) 3.6.4.- (7.9%)" "RNA helicase (92.1%) Acting on ATP; involved in cellular and subcellular movement (7.9%)" "GO:0009266 (1.3%) GO:0042255 (1.3%) GO:0009409 (0.4%)" "GO:0005829 (15.5%) GO:0005840 (0.4%)" "GO:0003724 (20.3%) GO:0005524 (20.3%) GO:0016787 (20.2%)" "response to temperature stimulus (1.3%) ribosome assembly (1.3%) response to cold (0.4%)" "cytosol (15.5%) ribosome (0.4%)" "RNA helicase activity (20.3%) ATP binding (20.3%) hydrolase activity (20.2%)" "IPR011545 (10.9%) IPR014001 (10.9%) IPR001650 (10.8%)" "DEAD/DEAH-box helicase domain (10.9%) Helicase superfamily 1/2, ATP-binding domain (10.9%) Helicase, C-terminal domain-like (10.8%)" TMGSHVTNWNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" YLFEFDYALLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR013783 (100%) Immunoglobulin-like fold (100%) FANPYQAAQYGYLDDVLEPR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.-.-.- (100%) Ligases (100%) "GO:0015977 (20.5%) GO:0006633 (5.9%)" GO:0009317 (20.5%) "GO:0004658 (22.2%) GO:0003989 (20.5%) GO:0016740 (9.4%)" "carbon fixation (20.5%) fatty acid biosynthetic process (5.9%)" acetyl-CoA carboxylase complex (20.5%) "propionyl-CoA carboxylase activity (22.2%) acetyl-CoA carboxylase activity (20.5%) transferase activity (9.4%)" "IPR034733 (19.3%) IPR051047 (19.3%) IPR011763 (19%)" "Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.3%) Acyl-CoA Carboxylase Beta Subunit (19.3%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19%)" TYWNLDK root "GO:0006401 (27.3%) GO:0006857 (2.3%) GO:0051999 (2.3%)" "GO:0032299 (27.3%) GO:0016020 (20.5%) GO:0030313 (2.3%)" "GO:0046873 (11.4%) GO:0000030 (2.3%) GO:0016788 (2.3%)" "RNA catabolic process (27.3%) oligopeptide transport (2.3%) mannosyl-inositol phosphorylceramide biosynthetic process (2.3%)" "ribonuclease H2 complex (27.3%) membrane (20.5%) cell envelope (2.3%)" "metal ion transmembrane transporter activity (11.4%) mannosyltransferase activity (2.3%) hydrolase activity, acting on ester bonds (2.3%)" "IPR013924 (24%) IPR002523 (10%) IPR045861 (10%)" "Ribonuclease H2, subunit C (24%) Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (10%) CorA, cytoplasmic domain (10%)" NVLMLGFMNQEAYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.4.19 (50%) 3.6.1.31 (50%)" "phosphoribosyl-AMP cyclohydrolase (50%) phosphoribosyl-ATP diphosphatase (50%)" GO:0000105 (20%) GO:0005737 (20%) "GO:0004635 (20%) GO:0004636 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "phosphoribosyl-AMP cyclohydrolase activity (20%) phosphoribosyl-ATP diphosphatase activity (20%) ATP binding (20%)" "IPR002496 (20%) IPR008179 (20%) IPR021130 (20%)" "Phosphoribosyl-AMP cyclohydrolase domain (20%) Phosphoribosyl-ATP pyrophosphohydrolase (20%) Phosphoribosyl-ATP pyrophosphohydrolase-like (20%)" CLNVASAPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.6.- (100%) Sulfuric ester hydrolases (100%) GO:0009244 (32.1%) "GO:0005886 (32.1%) GO:0016020 (2.5%)" "GO:0016776 (32.1%) GO:0016787 (1.2%)" lipopolysaccharide core region biosynthetic process (32.1%) "plasma membrane (32.1%) membrane (2.5%)" "phosphotransferase activity, phosphate group as acceptor (32.1%) hydrolase activity (1.2%)" "IPR000917 (25.5%) IPR012549 (25.5%) IPR040423 (25.5%)" "Sulfatase, N-terminal (25.5%) Phosphoethanolamine transferase, N-terminal (25.5%) Phosphoethanolamine transferase (25.5%)" LANLCVYVCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.2%) "GO:0005524 (25.2%) GO:0042802 (24.4%) GO:0004713 (18.9%)" plasma membrane (25.2%) "ATP binding (25.2%) identical protein binding (24.4%) protein tyrosine kinase activity (18.9%)" "IPR005702 (16.9%) IPR025669 (16.9%) IPR032807 (16.9%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (16.9%) AAA domain (16.9%) Tyrosine-protein kinase, G-rich domain (16.9%)" YPNLDMYSSDYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" EFSYSSYSQSYALPEDADQEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (33.3%) IPR008978 (33.3%) IPR031107 (33.3%)" "Alpha crystallin/Hsp20 domain (33.3%) HSP20-like chaperone (33.3%) Small heat shock protein (33.3%)" NFLETATR root "6.3.5.5 (76.9%) 6.3.4.16 (23.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (76.9%) carbamoyl-phosphate synthase (ammonia) (23.1%)" "GO:0006541 (14.1%) GO:0006526 (11.5%) GO:0006221 (11.4%)" "GO:0005737 (14.1%) GO:0005951 (0.1%) GO:0016602 (0.1%)" "GO:0004088 (14.2%) GO:0005524 (14.2%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) L-arginine biosynthetic process (11.5%) pyrimidine nucleotide biosynthetic process (11.4%)" "cytoplasm (14.1%) carbamoyl-phosphate synthase complex (0.1%) CCAAT-binding factor complex (0.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.2%) ATP binding (14.2%) metal ion binding (14.1%)" "IPR011607 (10.1%) IPR005479 (10.1%) IPR011761 (10.1%)" "Methylglyoxal synthase-like domain (10.1%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%)" YHLYVQVNPTSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR031762 (100%) Protein of unknown function DUF4738 (100%) EGYFDGTLFHR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (49.4%) GO:0003755 (50.6%) protein folding (49.4%) peptidyl-prolyl cis-trans isomerase activity (50.6%) "IPR002130 (25.5%) IPR044666 (25.5%) IPR020892 (24.8%)" "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain (25.5%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like (25.5%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (24.8%)" PVTCSDSDGYLYDPDGLDREK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.2%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" EMVNVAYR Pseudomonadati Bacteria Pseudomonadati 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (17.9%) GO:0044208 (17.9%) GO:0006188 (4.5%)" GO:0005829 (22.4%) "GO:0004018 (22.4%) GO:0070626 (14.9%)" "'de novo' IMP biosynthetic process (17.9%) 'de novo' AMP biosynthetic process (17.9%) IMP biosynthetic process (4.5%)" cytosol (22.4%) "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (22.4%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (14.9%)" "IPR000362 (9.6%) IPR004769 (9.6%) IPR008948 (9.6%)" "Fumarate lyase family (9.6%) Adenylosuccinate lyase (9.6%) L-Aspartase-like (9.6%)" HEFFPYPQTVMDKNPNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.8%) IPR012944 (34.8%) IPR033985 (30.4%)" "Tetratricopeptide-like helical domain superfamily (34.8%) RagB/SusD domain (34.8%) SusD-like, N-terminal (30.4%)" ASSYYVENGSYLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" ENNFLAAVHFGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006298 (16.9%) GO:0005829 (16.8%) "GO:0005524 (16.9%) GO:0030983 (16.9%) GO:0140664 (16.8%)" mismatch repair (16.9%) cytosol (16.8%) "ATP binding (16.9%) mismatched DNA binding (16.9%) ATP-dependent DNA damage sensor activity (16.8%)" "IPR007860 (8.5%) IPR007696 (8.4%) IPR045076 (8.4%)" "DNA mismatch repair protein MutS, connector domain (8.5%) DNA mismatch repair protein MutS, core (8.4%) DNA mismatch repair MutS (8.4%)" LDELLKEVSTLTAQNAEEVEQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002319 (14.3%) IPR004188 (14.3%) IPR004529 (14.3%)" "Phenylalanyl-tRNA synthetase (14.3%) Phenylalanine-tRNA ligase, class II, N-terminal (14.3%) Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (14.3%)" LPLDDSEK root "1.14.99.3 (40%) 2.6.1.- (40%) 1.14.14.18 (20%)" "Transferred entry: 1.14.14.18 (40%) Transaminases (40%) heme oxygenase (biliverdin-producing) (20%)" "GO:0006520 (11.6%) GO:0006788 (5.8%) GO:0006979 (5.8%)" "GO:0016020 (4.3%) GO:0005783 (2.9%)" "GO:0008483 (11.6%) GO:0030170 (11.6%) GO:0004392 (5.8%)" "amino acid metabolic process (11.6%) heme oxidation (5.8%) response to oxidative stress (5.8%)" "membrane (4.3%) endoplasmic reticulum (2.9%)" "transaminase activity (11.6%) pyridoxal phosphate binding (11.6%) heme oxygenase (decyclizing) activity (5.8%)" "IPR004839 (8%) IPR015421 (8%) IPR015422 (8%)" "Aminotransferase, class I/classII, large domain (8%) Pyridoxal phosphate-dependent transferase, major domain (8%) Pyridoxal phosphate-dependent transferase, small domain (8%)" MVKPLDLDEEMEYLLLNEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030153 (17.6%) GO:0016020 (82.4%) bacteriocin immunity (17.6%) membrane (82.4%) IPR009589 (100%) Uncharacterized protein YyaB-like, PH domain (100%) DMVWNTYLQNQLLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) "GO:0003755 (48%) GO:0016853 (2%)" plasma membrane (50%) "peptidyl-prolyl cis-trans isomerase activity (48%) isomerase activity (2%)" "IPR052029 (27.2%) IPR027304 (25%) IPR046357 (25%)" "Periplasmic chaperone PpiD (27.2%) Trigger factor/SurA domain superfamily (25%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25%)" ALMENYVEVAHTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.7%) IPR008969 (48.3%)" "Family of unknown function DUF5686 (51.7%) Carboxypeptidase-like, regulatory domain superfamily (48.3%)" NMGFELDLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (22.7%) IPR012910 (22.7%) IPR008969 (18.2%)" "TonB-dependent receptor-like, beta-barrel (22.7%) TonB-dependent receptor, plug domain (22.7%) Carboxypeptidase-like, regulatory domain superfamily (18.2%)" APAVATGLK root "1.2.7.3 (45.1%) 1.2.-.- (26.5%) 1.2.7.11 (16.8%)" "2-oxoglutarate synthase (45.1%) Acting on the aldehyde or oxo group of donors (26.5%) 2-oxoacid oxidoreductase (ferredoxin) (16.8%)" "GO:0044281 (10.4%) GO:0006082 (0.2%) GO:0044272 (0.2%)" "GO:0030976 (44.3%) GO:0016625 (41.2%) GO:0047553 (2.6%)" "small molecule metabolic process (10.4%) organic acid metabolic process (0.2%) sulfur compound biosynthetic process (0.2%)" "thiamine pyrophosphate binding (44.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (41.2%) 2-oxoglutarate synthase activity (2.6%)" "IPR029061 (32.7%) IPR011766 (32.6%) IPR051457 (32.6%)" "Thiamin diphosphate-binding fold (32.7%) Thiamine pyrophosphate enzyme, TPP-binding (32.6%) 2-oxoacid:ferredoxin oxidoreductase (32.6%)" MGFALAEECCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "4.1.1.36 (50%) 6.3.2.5 (50%)" "phosphopantothenoylcysteine decarboxylase (50%) phosphopantothenate--cysteine ligase (CTP) (50%)" "GO:0015937 (14.3%) GO:0015941 (14.3%)" GO:0071513 (14.3%) "GO:0004632 (14.3%) GO:0004633 (14.3%) GO:0010181 (14.3%)" "coenzyme A biosynthetic process (14.3%) pantothenate catabolic process (14.3%)" phosphopantothenoylcysteine decarboxylase complex (14.3%) "phosphopantothenate--cysteine ligase activity (14.3%) phosphopantothenoylcysteine decarboxylase activity (14.3%) FMN binding (14.3%)" "IPR003382 (20.6%) IPR005252 (20.6%) IPR007085 (20.6%)" "Flavoprotein (20.6%) Coenzyme A biosynthesis bifunctional protein CoaBC (20.6%) DNA/pantothenate metabolism flavoprotein, C-terminal (20.6%)" GMQSLDGNTPLFVVDGLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" LETYGVVETRPQSGTLVTEFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003677 (50%) GO:0003700 (50%)" "DNA binding (50%) DNA-binding transcription factor activity (50%)" "IPR000524 (20%) IPR008920 (20%) IPR011711 (20%)" "Transcription regulator HTH, GntR (20%) Transcription regulator FadR/GntR, C-terminal (20%) GntR, C-terminal (20%)" DNFFHCLVNAAHQFHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.4%) IPR024742 (20.4%) IPR032790 (20.4%)" "Glycogen debranching enzyme (20.4%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.4%) Glycogen debranching enzyme, C-terminal (20.4%)" GVCDHFGLTDEVDLLMGTFSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.3.1.47 (71.4%) 2.3.1.50 (28.6%)" "8-amino-7-oxononanoate synthase (71.4%) serine C-palmitoyltransferase (28.6%)" GO:0030148 (1.4%) GO:0016020 (1.4%) "GO:0030170 (47.1%) GO:0008483 (24.3%) GO:0016740 (19.3%)" sphingolipid biosynthetic process (1.4%) membrane (1.4%) "pyridoxal phosphate binding (47.1%) transaminase activity (24.3%) transferase activity (19.3%)" "IPR001917 (16.8%) IPR004839 (16.8%) IPR050087 (16.8%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.8%) Aminotransferase, class I/classII, large domain (16.8%) 8-amino-7-oxononanoate synthase class-II (16.8%)" GSQTYDMVSDPGQYYETHYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SLVGVYNPFSVCNALANLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR018631 (52%) IPR012547 (48%)" "AAA-ATPase-like domain (52%) PD-(D/E)XK nuclease superfamily 9 (48%)" EASGSLEQVDELLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25.1%) IPR005263 (25.1%) IPR020625 (25.1%)" "DapA-like (25.1%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25.1%) Schiff base-forming aldolase, active site (25.1%)" PELSLSQLVK Pseudomonadati Bacteria Pseudomonadati 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.1%) IPR015824 (33.1%) IPR036043 (33.1%)" "Phosphoglycerate kinase (33.1%) Phosphoglycerate kinase, N-terminal (33.1%) Phosphoglycerate kinase superfamily (33.1%)" WNFLQHLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006355 (50%) GO:0003677 (50%) regulation of DNA-templated transcription (50%) DNA binding (50%) "IPR012318 (26%) IPR014710 (26%) IPR018490 (24.7%)" "Crp-type HTH domain (26%) RmlC-like jelly roll fold (26%) Cyclic nucleotide-binding domain superfamily (24.7%)" ADMVLDLDQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KFNLFSLK root "7.2.1.1 (92.5%) 2.3.2.27 (2.5%) 2.7.8.- (2.5%)" "NADH:ubiquinone reductase (Na(+)-transporting) (92.5%) RING-type E3 ubiquitin transferase (2.5%) Transferases for other substituted phosphate groups (2.5%)" "GO:0006814 (14.1%) GO:0045944 (0.8%) GO:0002376 (0.4%)" "GO:0005886 (14.9%) GO:0016020 (1.5%) GO:0031011 (0.8%)" "GO:0009055 (14.1%) GO:0016655 (14.1%) GO:0046872 (14.1%)" "sodium ion transport (14.1%) positive regulation of transcription by RNA polymerase II (0.8%) immune system process (0.4%)" "plasma membrane (14.9%) membrane (1.5%) Ino80 complex (0.8%)" "electron transfer activity (14.1%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (14.1%) metal ion binding (14.1%)" "IPR001041 (9%) IPR001433 (9%) IPR008333 (9%)" "2Fe-2S ferredoxin-type iron-sulfur binding domain (9%) Oxidoreductase FAD/NAD(P)-binding (9%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (9%)" TLNYLLK root "3.2.1.21 (28.4%) 2.7.2.3 (11.4%) 3.6.1.5 (10.7%)" "beta-glucosidase (28.4%) phosphoglycerate kinase (11.4%) apyrase (10.7%)" "GO:0030245 (2.2%) GO:0009134 (2%) GO:0006096 (1.4%)" "GO:0016020 (4.4%) GO:0005886 (3.4%) GO:0005829 (2.5%)" "GO:0005524 (6.3%) GO:0008422 (3.3%) GO:0003677 (2.5%)" "cellulose catabolic process (2.2%) nucleoside diphosphate catabolic process (2%) glycolytic process (1.4%)" "membrane (4.4%) plasma membrane (3.4%) cytosol (2.5%)" "ATP binding (6.3%) beta-glucosidase activity (3.3%) DNA binding (2.5%)" "IPR013783 (2.7%) IPR017853 (2.5%) IPR001764 (2.3%)" "Immunoglobulin-like fold (2.7%) Glycoside hydrolase superfamily (2.5%) Glycoside hydrolase, family 3, N-terminal (2.3%)" EPNAAPQTPTLLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.3%) GO:0009279 (37.5%) GO:0015344 (31.3%) siderophore transmembrane transport (31.3%) cell outer membrane (37.5%) siderophore uptake transmembrane transporter activity (31.3%) "IPR057601 (25%) IPR036942 (20.8%) IPR039426 (20.8%)" "TonB-dependent transporter Oar-like, beta-barrel domain (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.8%) TonB-dependent receptor-like (20.8%)" LWWDKADVNLQPDFNPPFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (39.6%) IPR011990 (35.8%) IPR024302 (24.5%)" "SusD-like 2 (39.6%) Tetratricopeptide-like helical domain superfamily (35.8%) SusD-like (24.5%)" DKGAQQMFCESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.5%) IPR011990 (32.3%) IPR012944 (32.3%)" "SusD-like, N-terminal (35.5%) Tetratricopeptide-like helical domain superfamily (32.3%) RagB/SusD domain (32.3%)" VSLSYLGYKDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (17.2%) IPR057601 (17.2%) IPR008969 (16.4%)" "TonB-dependent receptor-like (17.2%) TonB-dependent transporter Oar-like, beta-barrel domain (17.2%) Carboxypeptidase-like, regulatory domain superfamily (16.4%)" KLFPDVPVALGGLEASLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0051539 (33.7%) GO:0003824 (32.6%) GO:0005506 (32.6%)" "4 iron, 4 sulfur cluster binding (33.7%) catalytic activity (32.6%) iron ion binding (32.6%)" "IPR013704 (14.8%) IPR022946 (14.8%) IPR006638 (14.3%)" "UPF0313, N-terminal (14.8%) Uncharacterised protein family UPF0313 (14.8%) Elp3/MiaA/NifB-like, radical SAM core domain (14.3%)" LHGVDWEGYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR012393 (14.3%) IPR028204 (14.3%) IPR005151 (14.1%)" "Tricorn protease (14.3%) Tricorn protease C1 domain (14.3%) Tail specific protease (14.1%)" YQAGFMGGADVEYR Pseudomonadati Bacteria Pseudomonadati IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) LNLTLDGETR root "GO:0001503 (12.8%) GO:0030509 (12.8%) GO:0051216 (12.8%)" "GO:0009279 (16.3%) GO:0005615 (12.8%) GO:0016020 (2.3%)" "GO:0005125 (12.8%) GO:0008083 (12.8%)" "ossification (12.8%) BMP signaling pathway (12.8%) cartilage development (12.8%)" "cell outer membrane (16.3%) extracellular space (12.8%) membrane (2.3%)" "cytokine activity (12.8%) growth factor activity (12.8%)" "IPR011990 (12.2%) IPR012944 (12.2%) IPR033985 (12.2%)" "Tetratricopeptide-like helical domain superfamily (12.2%) RagB/SusD domain (12.2%) SusD-like, N-terminal (12.2%)" GNKHFPGENVAQGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001684 (51.3%) IPR018261 (48.7%)" "Large ribosomal subunit protein bL27 (51.3%) Large ribosomal subunit protein bL27, conserved site (48.7%)" TCLEAYSR Bacteria Bacteria 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR006691 (12.8%) IPR050220 (12.8%) IPR002205 (12.6%)" "DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%) Type II DNA Topoisomerases (12.8%) DNA topoisomerase, type IIA, domain A (12.6%)" TFDAGFDLSMFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LNSLSLGFFSEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005886 (21.7%) GO:0016020 (3.1%)" "GO:0005524 (24.8%) GO:0016887 (24%) GO:0015421 (22.5%)" "plasma membrane (21.7%) membrane (3.1%)" "ATP binding (24.8%) ATP hydrolysis activity (24%) ABC-type oligopeptide transporter activity (22.5%)" "IPR011527 (15%) IPR003439 (14.6%) IPR003593 (14.6%)" "ABC transporter type 1, transmembrane domain (15%) ABC transporter-like, ATP-binding domain (14.6%) AAA+ ATPase domain (14.6%)" ATAAALKEQLAQEVAQLVAAGGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.5.1.5 (50%) 3.5.4.9 (50%)" "methylenetetrahydrofolate dehydrogenase (NADP(+)) (50%) methenyltetrahydrofolate cyclohydrolase (50%)" "GO:0035999 (14.7%) GO:0000105 (13.8%) GO:0006164 (13.8%)" GO:0005829 (14.7%) "GO:0004477 (14.7%) GO:0004488 (14.7%)" "tetrahydrofolate interconversion (14.7%) L-histidine biosynthetic process (13.8%) purine nucleotide biosynthetic process (13.8%)" cytosol (14.7%) "methenyltetrahydrofolate cyclohydrolase activity (14.7%) methylenetetrahydrofolate dehydrogenase (NADP+) activity (14.7%)" "IPR000672 (16.7%) IPR020630 (16.7%) IPR020631 (16.7%)" "Tetrahydrofolate dehydrogenase/cyclohydrolase (16.7%) Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (16.7%) Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (16.7%)" CLMFGMNMNNVAVTDGDRVEFEQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (24.1%) GO:0046872 (0.9%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (24.1%) metal ion binding (0.9%)" "IPR003762 (14.5%) IPR024664 (14.5%) IPR055389 (14.5%)" "L-arabinose isomerase (14.5%) L-arabinose isomerase, C-terminal (14.5%) L-arabinose isomerase, N-terminal domain (14.5%)" LTYPWSMLDK Bacteria Bacteria GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013131 (17.6%) IPR050988 (17.6%) IPR013118 (17%)" "Mannitol dehydrogenase, N-terminal (17.6%) Mannitol Dehydrogenase/Oxidoreductase (17.6%) Mannitol dehydrogenase, C-terminal (17%)" EYSSLLEK root "3.4.24.- (82.1%) 2.7.7.7 (7.4%) 5.6.2.2 (4.2%)" "Metalloendopeptidases (82.1%) DNA-directed DNA polymerase (7.4%) DNA topoisomerase (ATP-hydrolyzing) (4.2%)" "GO:0006508 (14.2%) GO:0006518 (13.4%) GO:0032259 (2.8%)" "GO:0005829 (2%) GO:0005737 (1.5%) GO:0005886 (1.3%)" "GO:0004222 (13.8%) GO:0046872 (13.8%) GO:0008168 (2.4%)" "proteolysis (14.2%) peptide metabolic process (13.4%) methylation (2.8%)" "cytosol (2%) cytoplasm (1.5%) plasma membrane (1.3%)" "metalloendopeptidase activity (13.8%) metal ion binding (13.8%) methyltransferase activity (2.4%)" "IPR001567 (9.8%) IPR042088 (9.8%) IPR004438 (9.7%)" "Peptidase M3A/M3B catalytic domain (9.8%) Oligoendopeptidase F, C-terminal domain (9.8%) Peptidase M3B, oligoendopeptidase F (9.7%)" TTVEYSELSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.99.6 (95%) 3.1.1.31 (5%)" "glucosamine-6-phosphate deaminase (95%) 6-phosphogluconolactonase (5%)" "GO:0005975 (31.6%) GO:0006044 (31.6%)" "GO:0004342 (34.2%) GO:0016787 (2.6%)" "carbohydrate metabolic process (31.6%) N-acetylglucosamine metabolic process (31.6%)" "glucosamine-6-phosphate deaminase activity (34.2%) hydrolase activity (2.6%)" "IPR037171 (17.4%) IPR052960 (17.4%) IPR003737 (16.5%)" "NagB/RpiA transferase-like (17.4%) Glucosamine-6-phosphate deaminase-like (17.4%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (16.5%)" DATDTTEADEDDFNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (47.2%) "GO:0022857 (47.2%) GO:0005524 (5.6%)" plasma membrane (47.2%) "transmembrane transporter activity (47.2%) ATP binding (5.6%)" "IPR003838 (34.7%) IPR050250 (34.7%) IPR025857 (30.6%)" "ABC3 transporter permease, C-terminal (34.7%) Macrolide Exporter MacB (34.7%) MacB-like periplasmic core domain (30.6%)" KEVESLYNVTVVDVNTLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20.8%) "GO:0005840 (20.8%) GO:1990904 (20.8%)" "GO:0003735 (20.8%) GO:0019843 (16.7%)" translation (20.8%) "ribosome (20.8%) ribonucleoprotein complex (20.8%)" "structural constituent of ribosome (20.8%) rRNA binding (16.7%)" "IPR012677 (33.3%) IPR012678 (33.3%) IPR013025 (33.3%)" "Nucleotide-binding alpha-beta plait domain superfamily (33.3%) Ribosomal protein uL23/eL15/eS24 core domain superfamily (33.3%) Large ribosomal subunit protein uL23-like (33.3%)" VGEVSAPFTMVNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (27.1%) IPR046357 (25%) IPR050280 (25%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (27.1%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25%) Outer Membrane Protein Chaperone SurA (25%)" WALSPTVSAAWVLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" VVNLPSFAVKPGMVVGVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (19%) GO:0042274 (19%)" "GO:0015935 (19%) GO:0005840 (2.4%)" "GO:0003735 (19%) GO:0019843 (19%) GO:0003723 (2.4%)" "translation (19%) ribosomal small subunit biogenesis (19%)" "small ribosomal subunit (19%) ribosome (2.4%)" "structural constituent of ribosome (19%) rRNA binding (19%) RNA binding (2.4%)" "IPR036986 (18.4%) IPR001912 (16.3%) IPR002942 (16.3%)" "RNA-binding S4 domain superfamily (18.4%) Small ribosomal subunit protein uS4, N-terminal (16.3%) RNA-binding S4 domain (16.3%)" DTFPALALAASYLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.7.7.13 (66.7%) 5.3.1.8 (33.3%)" "mannose-1-phosphate guanylyltransferase (66.7%) mannose-6-phosphate isomerase (33.3%)" "GO:0009298 (25.8%) GO:0005976 (24.2%)" "GO:0004475 (25.8%) GO:0000166 (22%) GO:0016853 (1.5%)" "GDP-mannose biosynthetic process (25.8%) polysaccharide metabolic process (24.2%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (25.8%) nucleotide binding (22%) isomerase activity (1.5%)" "IPR005835 (16.9%) IPR051161 (16.9%) IPR001538 (15.9%)" "Nucleotidyl transferase domain (16.9%) Mannose-6-phosphate isomerase type 2 (16.9%) Mannose-6-phosphate isomerase, type II, C-terminal (15.9%)" KNSAEVLNAVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" SSFTGSAGVVDADKLAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" AFCPLGLGLVPYQLPGSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.19 (100%) rhamnulose-1-phosphate aldolase (100%) GO:0019323 (33.3%) GO:0005829 (33.3%) "GO:0016832 (20%) GO:0008994 (13.3%)" pentose catabolic process (33.3%) cytosol (33.3%) "aldehyde-lyase activity (20%) rhamnulose-1-phosphate aldolase activity (13.3%)" "IPR001303 (33.3%) IPR036409 (33.3%) IPR050197 (33.3%)" "Class II aldolase/adducin N-terminal (33.3%) Class II aldolase/adducin N-terminal domain superfamily (33.3%) Aldolase class II family, sugar metabolism enzymes (33.3%)" LLDELDPTAFVSQSAVLGVYGEGFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) "IPR003740 (25%) IPR015867 (25%) IPR019264 (25%)" "Uncharacterised membrane protein YitT (25%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25%) Domain of unknown function DUF2179 (25%)" HTLCTMVQLNENNEEAGHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (47.1%) GO:0003746 (52.9%) cytoplasm (47.1%) translation elongation factor activity (52.9%) "IPR014039 (20.7%) IPR036402 (20.7%) IPR001816 (19.5%)" "Translation elongation factor EFTs/EF1B, dimerisation (20.7%) Elongation factor Ts, dimerisation domain superfamily (20.7%) Translation elongation factor EFTs/EF1B (19.5%)" ACASHCVMSGPASER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (10.9%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (10.9%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (17.4%) IPR005946 (17.4%) IPR029057 (17.4%)" "Phosphoribosyltransferase domain (17.4%) Ribose-phosphate pyrophosphokinase (17.4%) Phosphoribosyltransferase-like (17.4%)" YDYGTPACYGMTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" KSVVTAALAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR039426 (13.3%) IPR023996 (12.8%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent receptor-like (13.3%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" TKEYLDELEFLADTAGAVTVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0043022 (20%)" cytoplasm (20%) "GTPase activity (20%) GTP binding (20%) ribosome binding (20%)" "IPR006073 (13.3%) IPR016496 (13.3%) IPR025121 (13.3%)" "GTP binding domain (13.3%) GTPase HflX (13.3%) GTPase HflX, N-terminal (13.3%)" AYMDVKPNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" LNATAALANSDTYAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (18%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (18%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" EQVEQAVQLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030170 (50%) GO:0008483 (46.2%) GO:0016740 (3.8%)" "pyridoxal phosphate binding (50%) transaminase activity (46.2%) transferase activity (3.8%)" "IPR015422 (17.5%) IPR015424 (17.5%) IPR001917 (16.3%)" "Pyridoxal phosphate-dependent transferase, small domain (17.5%) Pyridoxal phosphate-dependent transferase (17.5%) Aminotransferase, class-II, pyridoxal-phosphate binding site (16.3%)" AEAPHLAEPLAVGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (100%) plasma membrane (100%) "IPR002810 (34.6%) IPR052165 (34.6%) IPR012340 (30.8%)" "NfeD-like, C-terminal domain (34.6%) Membrane-associated protease and related proteins (34.6%) Nucleic acid-binding, OB-fold (30.8%)" NAQVETVTDANGLSAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (92.9%) GO:0016020 (7.1%)" "cell outer membrane (92.9%) membrane (7.1%)" "IPR006665 (20.6%) IPR027367 (20.6%) IPR050330 (20.6%)" "OmpA-like domain (20.6%) YMGG-like Gly-zipper (20.6%) Bacterial Outer Membrane Structural/Functional (20.6%)" NGKGDYTLTPYTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.8%) IPR012910 (20.8%) IPR039426 (20.8%)" "TonB-dependent receptor-like, beta-barrel (20.8%) TonB-dependent receptor, plug domain (20.8%) TonB-dependent receptor-like (20.8%)" CFEFDVK root "2.5.1.- (33.3%) 3.2.1.- (33.3%) 7.1.1.2 (33.3%)" "Transferring alkyl or aryl groups, other than methyl groups (33.3%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (33.3%) NADH:ubiquinone reductase (H(+)-translocating) (33.3%)" "GO:0005975 (41%) GO:0007165 (2.9%) GO:0015990 (1%)" "GO:0005743 (1%) GO:0005783 (1%)" "GO:0004553 (41%) GO:0004672 (2.9%) GO:0005524 (2.9%)" "carbohydrate metabolic process (41%) signal transduction (2.9%) electron transport coupled proton transport (1%)" "mitochondrial inner membrane (1%) endoplasmic reticulum (1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (41%) protein kinase activity (2.9%) ATP binding (2.9%)" "IPR006710 (18.6%) IPR041542 (18.6%) IPR051795 (18.6%)" "Glycoside hydrolase, family 43 (18.6%) Beta-xylosidase, C-terminal Concanavalin A-like domain (18.6%) Glycosyl Hydrolase Family 43 (18.6%)" LTRPGLTYLNPYVDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (25%) IPR036942 (25%) IPR037066 (25%)" "TonB-dependent receptor, plug domain (25%) TonB-dependent receptor-like, beta-barrel domain superfamily (25%) TonB-dependent receptor, plug domain superfamily (25%)" VTTLLGAR root "5.1.1.1 (95.7%) 1.18.1.2 (1.1%) 1.8.1.- (1.1%)" "alanine racemase (95.7%) ferredoxin--NADP(+) reductase (1.1%) With NAD(+) or NADP(+) as acceptor (1.1%)" "GO:0030632 (13.8%) GO:0044205 (1.4%) GO:0006221 (1.1%)" "GO:0005886 (0.8%) GO:0016020 (0.8%) GO:0005634 (0.5%)" "GO:0005524 (14.1%) GO:0008784 (13.8%) GO:0030170 (13.8%)" "D-alanine biosynthetic process (13.8%) 'de novo' UMP biosynthetic process (1.4%) pyrimidine nucleotide biosynthetic process (1.1%)" "plasma membrane (0.8%) membrane (0.8%) nucleus (0.5%)" "ATP binding (14.1%) alanine racemase activity (13.8%) pyridoxal phosphate binding (13.8%)" "IPR000821 (7.6%) IPR001608 (7.6%) IPR011079 (7.6%)" "Alanine racemase (7.6%) Alanine racemase, N-terminal (7.6%) Alanine racemase, C-terminal (7.6%)" AEGQGGFDNGTLVNTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR003961 (26.2%) IPR033803 (26.2%) IPR013783 (23.8%)" "Fibronectin type III (26.2%) Golvesin/Xly, CBD-like (26.2%) Immunoglobulin-like fold (23.8%)" FLVEMQNAYQTYFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071973 (33.3%) GO:0009288 (33.3%) GO:0003774 (33.3%) bacterial-type flagellum-dependent cell motility (33.3%) bacterial-type flagellum (33.3%) cytoskeletal motor activity (33.3%) "IPR010106 (99.2%) IPR000563 (0.8%)" "Recombination-promoting nuclease RpnA (99.2%) Flagellar assembly protein FliH (0.8%)" GLRNEDGSGVLVGLTNLGNVVGYER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (15.3%) GO:0046912 (9.7%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (15.3%) acyltransferase activity, acyl groups converted into alkyl on transfer (9.7%)" "IPR002020 (20.9%) IPR016142 (19.8%) IPR016143 (19.8%)" "Citrate synthase (20.9%) Citrate synthase-like, large alpha subdomain (19.8%) Citrate synthase-like, small alpha subdomain (19.8%)" LNNFSMANLFNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0071709 (48.6%) "GO:0009279 (48.6%) GO:0019867 (2.8%)" membrane assembly (48.6%) "cell outer membrane (48.6%) outer membrane (2.8%)" "IPR010827 (25.2%) IPR034746 (24.5%) IPR023707 (23.8%)" "POTRA domain, BamA/TamA-like (25.2%) POTRA domain (24.5%) Outer membrane protein assembly factor BamA (23.8%)" TVQVFVPYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) QGGGEQATMSMEEFAQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" QDDLLSHLVQNPNLQLLPNTSGVR Pseudomonadati Bacteria Pseudomonadati 2.8.1.10 (100%) thiazole synthase (100%) "GO:0009229 (31%) GO:0009228 (9.5%)" GO:0005737 (28.6%) "GO:1990107 (21.4%) GO:0016783 (9.5%)" "thiamine diphosphate biosynthetic process (31%) thiamine biosynthetic process (9.5%)" cytoplasm (28.6%) "thiazole synthase activity (21.4%) sulfurtransferase activity (9.5%)" "IPR008867 (33.3%) IPR013785 (33.3%) IPR033983 (33.3%)" "Thiazole synthase (33.3%) Aldolase-type TIM barrel (33.3%) Thiazole synthase ThiG (33.3%)" VYLTEGTGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20.3%) IPR014721 (20.3%) IPR020568 (20.3%)" "Small ribosomal subunit protein uS9 (20.3%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (20.3%) Ribosomal protein uS5 domain 2-type superfamily (20.3%)" DLHLLTLPEMYLVAAEAYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.7%) IPR033985 (33.7%) IPR011990 (32.6%)" "RagB/SusD domain (33.7%) SusD-like, N-terminal (33.7%) Tetratricopeptide-like helical domain superfamily (32.6%)" FFAHNEELDLCWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001173 (50.7%) IPR029044 (49.3%)" "Glycosyltransferase 2-like (50.7%) Nucleotide-diphospho-sugar transferases (49.3%)" YEPEMNMYVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.1%) GO:0005737 (49.1%)" GO:0016787 (1.8%) "extracellular region (49.1%) cytoplasm (49.1%)" hydrolase activity (1.8%) "IPR006530 (15.8%) IPR050708 (15.4%) IPR031325 (14.9%)" "YD repeat (15.8%) Type VI secretion system VgrG/RHS (15.4%) RHS repeat (14.9%)" LLGSAYLSPDGKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR013780 (25%) IPR017853 (25%) IPR039514 (25%)" "Glycosyl hydrolase, all-beta (25%) Glycoside hydrolase superfamily (25%) Endo-beta-1,6-galactanase-like (25%)" YHGAGMLLSQLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25.2%) "GO:0004834 (25.2%) GO:0052684 (25.2%) GO:0030170 (24.4%)" cytoplasm (25.2%) "tryptophan synthase activity (25.2%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25.2%) pyridoxal phosphate binding (24.4%)" "IPR001926 (22.2%) IPR023026 (22.2%) IPR006316 (21.6%)" "Tryptophan synthase beta chain-like, PALP domain (22.2%) Tryptophan synthase beta chain/beta chain-like (22.2%) Tryptophan synthase, beta chain-like (21.6%)" KWETLYPLDSYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.1 (100%) alkaline phosphatase (100%) GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.6%) IPR026263 (33.6%) IPR017850 (31.8%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.6%) Alkaline phosphatase, prokaryotic (33.6%) Alkaline-phosphatase-like, core domain superfamily (31.8%)" MEAPLYPELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (24%) IPR057601 (24%) IPR036942 (20%)" "TonB-dependent receptor-like (24%) TonB-dependent transporter Oar-like, beta-barrel domain (24%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" LAGVELDYLCSTHGPVWHEHLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0010181 (26.7%) GO:0009055 (24.4%) GO:0016491 (24.4%)" "FMN binding (26.7%) electron transfer activity (24.4%) oxidoreductase activity (24.4%)" "IPR001279 (17.4%) IPR008254 (17.4%) IPR045761 (17.4%)" "Metallo-beta-lactamase (17.4%) Flavodoxin/nitric oxide synthase (17.4%) ODP domain (17.4%)" GVLTSDRENLTEQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.6%) "GO:0016746 (16.9%) GO:0046872 (16.9%) GO:0051287 (16.9%)" malate metabolic process (16.6%) "acyltransferase activity (16.9%) metal ion binding (16.9%) NAD binding (16.9%)" "IPR002505 (9.2%) IPR012301 (9.2%) IPR012302 (9.2%)" "Phosphate acetyl/butaryl transferase (9.2%) Malic enzyme, N-terminal domain (9.2%) Malic enzyme, NAD-binding (9.2%)" LFLNGLFK root "2.7.4.9 (50%) 3.1.-.- (50%)" "dTMP kinase (50%) Acting on ester bonds (50%)" "GO:0005975 (9.4%) GO:0006869 (3.1%) GO:0007018 (3.1%)" "GO:0016020 (18.8%) GO:0005886 (6.3%) GO:0005576 (3.1%)" "GO:0016757 (6.3%) GO:0022857 (6.3%) GO:0030246 (6.3%)" "carbohydrate metabolic process (9.4%) lipid transport (3.1%) microtubule-based movement (3.1%)" "membrane (18.8%) plasma membrane (6.3%) extracellular region (3.1%)" "glycosyltransferase activity (6.3%) transmembrane transporter activity (6.3%) carbohydrate binding (6.3%)" "IPR052519 (28%) IPR043129 (27.3%) IPR008928 (2%)" "Eukaryotic-type N-acetylglucosamine Kinase (28%) ATPase, nucleotide binding domain (27.3%) Six-hairpin glycosidase superfamily (2%)" SLENDYALFTNNVNNPLTPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (88.9%) IPR011250 (11.1%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (88.9%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (11.1%)" AQTNLSYATLTSPLDGTVLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR006143 (33.3%) IPR032317 (33.3%)" "Outer membrane efflux protein (33.3%) RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%)" RGELLTLLNK root 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0005975 (32.9%) GO:0016192 (20.5%) GO:0007173 (1.4%)" GO:0016020 (1.4%) "GO:0004650 (32.9%) GO:0004557 (8.2%) GO:0005154 (1.4%)" "carbohydrate metabolic process (32.9%) vesicle-mediated transport (20.5%) epidermal growth factor receptor signaling pathway (1.4%)" membrane (1.4%) "polygalacturonase activity (32.9%) alpha-galactosidase activity (8.2%) epidermal growth factor receptor binding (1.4%)" "IPR000743 (9.1%) IPR006626 (9.1%) IPR010905 (9.1%)" "Glycoside hydrolase, family 28 (9.1%) Parallel beta-helix repeat (9.1%) Glycosyl hydrolase, family 88 (9.1%)" TKELEETVEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000723 (25.2%) GO:0006281 (25.2%)" GO:0016020 (24.5%) GO:0003678 (25.2%) "telomere maintenance (25.2%) DNA repair (25.2%)" membrane (24.5%) DNA helicase activity (25.2%) "IPR003593 (20.2%) IPR010285 (20.2%) IPR029491 (20.2%)" "AAA+ ATPase domain (20.2%) DNA helicase Pif1-like, DEAD-box helicase domain (20.2%) Helicase Helix-turn-helix domain (20.2%)" TMVTVLEAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (20%) "GO:0005524 (20%) GO:0005525 (20%) GO:0016887 (20%)" cytoplasm (20%) "ATP binding (20%) GTP binding (20%) ATP hydrolysis activity (20%)" "IPR004095 (10.7%) IPR004396 (10.7%) IPR006073 (10.7%)" "TGS (10.7%) Ribosome-binding ATPase YchF/Obg-like ATPase 1 (10.7%) GTP binding domain (10.7%)" LFPELTALENVELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (24.7%) "GO:0005524 (25.9%) GO:0016887 (24.7%) GO:0022857 (24.7%)" plasma membrane (24.7%) "ATP binding (25.9%) ATP hydrolysis activity (24.7%) transmembrane transporter activity (24.7%)" "IPR003439 (30.4%) IPR015854 (30.4%) IPR027417 (30.4%)" "ABC transporter-like, ATP-binding domain (30.4%) ABC transporter, lipoprotein release, LolD-like (30.4%) P-loop containing nucleoside triphosphate hydrolase (30.4%)" TTVEAFLK root "6.1.1.15 (44.4%) 6.1.1.17 (44.4%) 3.4.11.2 (11.1%)" "proline--tRNA ligase (44.4%) glutamate--tRNA ligase (44.4%) membrane alanyl aminopeptidase (11.1%)" "GO:0006424 (3.3%) GO:0006433 (3.3%) GO:0006412 (0.8%)" "GO:0005737 (4.1%) GO:0017101 (3.3%) GO:0005840 (0.8%)" "GO:0016491 (30.6%) GO:0051536 (28.1%) GO:0003723 (3.3%)" "glutamyl-tRNA aminoacylation (3.3%) prolyl-tRNA aminoacylation (3.3%) translation (0.8%)" "cytoplasm (4.1%) aminoacyl-tRNA synthetase multienzyme complex (3.3%) ribosome (0.8%)" "oxidoreductase activity (30.6%) iron-sulfur cluster binding (28.1%) RNA binding (3.3%)" "IPR023753 (13.3%) IPR028261 (13.3%) IPR009051 (12.9%)" "FAD/NAD(P)-binding domain (13.3%) Dihydroprymidine dehydrogenase domain II (13.3%) Alpha-helical ferredoxin (12.9%)" ENGRPLTDSELFGFAQLNSEHCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.2%) IPR010918 (11.2%) IPR040707 (11.2%)" "Phosphoribosylformylglycinamidine synthase PurL (11.2%) PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.2%)" TNQHMTEETLHEFLQGLNVSDSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (22.2%) GO:0044208 (22.2%) GO:0006188 (14.8%)" "GO:0004018 (37%) GO:0070626 (3.7%)" "'de novo' IMP biosynthetic process (22.2%) 'de novo' AMP biosynthetic process (22.2%) IMP biosynthetic process (14.8%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (37%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (3.7%)" "IPR000362 (12.5%) IPR004769 (12.5%) IPR008948 (12.5%)" "Fumarate lyase family (12.5%) Adenylosuccinate lyase (12.5%) L-Aspartase-like (12.5%)" DAYDENDKLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR013830 (25.5%) IPR036514 (25.5%) IPR037459 (25.5%)" "SGNH hydrolase-type esterase domain (25.5%) SGNH hydrolase superfamily (25.5%) Rhamnogalacturonan acetylesterase RhgT-like (25.5%)" PLAWFDR root "2.3.2.27 (14.5%) 1.6.99.5 (12%) 3.1.3.27 (11.1%)" "RING-type E3 ubiquitin transferase (14.5%) Transferred entry: 1.6.5.11 (12%) phosphatidylglycerophosphatase (11.1%)" "GO:0015990 (16.6%) GO:0042773 (16.6%) GO:0016567 (0.8%)" "GO:0016020 (18.1%) GO:0012505 (15.8%) GO:0005886 (2.2%)" "GO:0008137 (16.6%) GO:0005524 (1.4%) GO:0004672 (0.8%)" "electron transport coupled proton transport (16.6%) ATP synthesis coupled electron transport (16.6%) protein ubiquitination (0.8%)" "membrane (18.1%) endomembrane system (15.8%) plasma membrane (2.2%)" "NADH dehydrogenase (ubiquinone) activity (16.6%) ATP binding (1.4%) protein kinase activity (0.8%)" "IPR003945 (18.1%) IPR001750 (17.9%) IPR001516 (17.5%)" "NADH-quinone oxidoreductase, chain 5-like (18.1%) NADH:quinone oxidoreductase/Mrp antiporter, transmembrane domain (17.9%) NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal (17.5%)" VEFLNVPGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) YGDDMVDLVRDWVTVAEDGYLTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25%) IPR035376 (25%) IPR038143 (25%)" "NigD-like N-terminal OB domain (25%) NigD-like, C-terminal domain (25%) NigD-like, C-terminal domain superfamily (25%)" SLLGTANTDWNDEVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (8%) GO:0009279 (84%) GO:0015344 (8%) siderophore transmembrane transport (8%) cell outer membrane (84%) siderophore uptake transmembrane transporter activity (8%) "IPR012910 (12.4%) IPR023997 (12.4%) IPR039426 (12.4%)" "TonB-dependent receptor, plug domain (12.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.4%) TonB-dependent receptor-like (12.4%)" LTGELSFAGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.1.26.- (88.9%) 3.1.4.- (11.1%)" "Endoribonucleases producing 5'-phosphomonoesters (88.9%) Phosphoric diester hydrolases (11.1%)" GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR004659 (25.1%) IPR019307 (25.1%) IPR003029 (24.9%)" "Ribonuclease E/G (25.1%) RNA-binding protein AU-1/Ribonuclease E/G (25.1%) S1 domain (24.9%)" ATESTSNTQFTYEELWQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DVAAECGVSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0043200 (32.1%) GO:0006355 (0.4%)" "GO:0005829 (32.1%) GO:0016020 (0.2%)" "GO:0043565 (35%) GO:0003700 (0.2%)" "response to amino acid (32.1%) regulation of DNA-templated transcription (0.4%)" "cytosol (32.1%) membrane (0.2%)" "sequence-specific DNA binding (35%) DNA-binding transcription factor activity (0.2%)" "IPR000485 (16.5%) IPR036388 (16.5%) IPR036390 (16.5%)" "AsnC-type HTH domain (16.5%) Winged helix-like DNA-binding domain superfamily (16.5%) Winged helix DNA-binding domain superfamily (16.5%)" LFLAQEEEKQDNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) FPNDELGELAER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016036 (19.8%) "GO:0005886 (19.8%) GO:0016020 (0.6%)" "GO:0000155 (19.8%) GO:0004721 (19.8%) GO:0005524 (19.8%)" cellular response to phosphate starvation (19.8%) "plasma membrane (19.8%) membrane (0.6%)" "phosphorelay sensor kinase activity (19.8%) phosphoprotein phosphatase activity (19.8%) ATP binding (19.8%)" "IPR003594 (14.6%) IPR003661 (14.6%) IPR005467 (14.6%)" "Histidine kinase/HSP90-like ATPase domain (14.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (14.6%) Histidine kinase domain (14.6%)" QVLGEDTDVKDETAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (14.3%) GO:0043335 (14.3%) GO:0051083 (14.3%)" GO:0005737 (14.3%) "GO:0003755 (14.3%) GO:0043022 (14.3%) GO:0044183 (14.3%)" "protein transport (14.3%) protein unfolding (14.3%) 'de novo' cotranslational protein folding (14.3%)" cytoplasm (14.3%) "peptidyl-prolyl cis-trans isomerase activity (14.3%) ribosome binding (14.3%) protein folding chaperone (14.3%)" "IPR005215 (16.7%) IPR008880 (16.7%) IPR008881 (16.7%)" "Trigger factor (16.7%) Trigger factor, C-terminal (16.7%) Trigger factor, ribosome-binding, bacterial (16.7%)" TYWDNANTYSQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006826 (47.4%) GO:0006811 (2.6%)" GO:0009279 (50%) "iron ion transport (47.4%) monoatomic ion transport (2.6%)" cell outer membrane (50%) "IPR000531 (25.5%) IPR039426 (25.5%) IPR012910 (24.8%)" "TonB-dependent receptor-like, beta-barrel (25.5%) TonB-dependent receptor-like (25.5%) TonB-dependent receptor, plug domain (24.8%)" LCDYLEEDGLNFNQALELVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" NVVVFNAYEYYPLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.99.6 (91.7%) 3.1.1.31 (8.3%)" "glucosamine-6-phosphate deaminase (91.7%) 6-phosphogluconolactonase (8.3%)" "GO:0005975 (33.3%) GO:0006044 (33.3%)" GO:0004342 (33.3%) "carbohydrate metabolic process (33.3%) N-acetylglucosamine metabolic process (33.3%)" glucosamine-6-phosphate deaminase activity (33.3%) "IPR004547 (17.2%) IPR006148 (17.2%) IPR052960 (17.2%)" "Glucosamine-6-phosphate isomerase (17.2%) Glucosamine/galactosamine-6-phosphate isomerase (17.2%) Glucosamine-6-phosphate deaminase-like (17.2%)" TLPMLPER root "3.1.13.1 (71.8%) 5.6.2.1 (25.7%) 2.1.1.207 (1.7%)" "exoribonuclease II (71.8%) DNA topoisomerase (25.7%) tRNA (cytidine(34)-2'-O)-methyltransferase (1.7%)" "GO:0006402 (15.4%) GO:0006265 (5.8%) GO:0006281 (5.8%)" "GO:0005829 (15.4%) GO:0043597 (5.8%) GO:0005737 (0.4%)" "GO:0003723 (15.9%) GO:0008859 (15.4%) GO:0003917 (5.8%)" "mRNA catabolic process (15.4%) DNA topological change (5.8%) DNA repair (5.8%)" "cytosol (15.4%) cytoplasmic replication fork (5.8%) cytoplasm (0.4%)" "RNA binding (15.9%) exoribonuclease II activity (15.4%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (5.8%)" "IPR001900 (7.3%) IPR050180 (7.3%) IPR022966 (7.3%)" "Ribonuclease II/R (7.3%) RNR Ribonuclease (7.3%) Ribonuclease II/R, conserved site (7.3%)" EFLSDPK root "4.98.1.1 (21.3%) 3.1.3.16 (17%) 2.7.1.137 (14.9%)" "protoporphyrin ferrochelatase (21.3%) protein-serine/threonine phosphatase (17%) phosphatidylinositol 3-kinase (14.9%)" "GO:0042956 (1.5%) GO:0006869 (1.3%) GO:0051017 (1.2%)" "GO:0005737 (3.4%) GO:0016020 (2.3%) GO:0005886 (2.1%)" "GO:0008239 (5.5%) GO:0005524 (4.1%) GO:0016740 (3.2%)" "maltodextrin transmembrane transport (1.5%) lipid transport (1.3%) actin filament bundle assembly (1.2%)" "cytoplasm (3.4%) membrane (2.3%) plasma membrane (2.1%)" "dipeptidyl-peptidase activity (5.5%) ATP binding (4.1%) transferase activity (3.2%)" "IPR029044 (5%) IPR029058 (4.4%) IPR000383 (3.9%)" "Nucleotide-diphospho-sugar transferases (5%) Alpha/Beta hydrolase fold (4.4%) Xaa-Pro dipeptidyl-peptidase-like domain (3.9%)" RFGEPLFGADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (19.9%) GO:0042274 (19.9%)" "GO:0015935 (19.9%) GO:0005840 (0.2%)" "GO:0019843 (20.1%) GO:0003735 (19.9%)" "translation (19.9%) ribosomal small subunit biogenesis (19.9%)" "small ribosomal subunit (19.9%) ribosome (0.2%)" "rRNA binding (20.1%) structural constituent of ribosome (19.9%)" "IPR001912 (16.8%) IPR036986 (16.8%) IPR002942 (16.6%)" "Small ribosomal subunit protein uS4, N-terminal (16.8%) RNA-binding S4 domain superfamily (16.8%) RNA-binding S4 domain (16.6%)" VLFCCGETLEEREAEK Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.7%) GO:0006096 (12.7%) GO:0019563 (12.7%)" "GO:0005829 (12.7%) GO:0016020 (12%)" GO:0004807 (12.7%) "gluconeogenesis (12.7%) glycolytic process (12.7%) glycerol catabolic process (12.7%)" "cytosol (12.7%) membrane (12%)" triose-phosphate isomerase activity (12.7%) "IPR000652 (17.1%) IPR020861 (17.1%) IPR022896 (16.8%)" "Triosephosphate isomerase (17.1%) Triosephosphate isomerase, active site (17.1%) Triosephosphate isomerase, bacterial/eukaryotic (16.8%)" SFGLHNMTLLLGHENYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SLDTNPELDLSYKDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19%) "GO:0000155 (20.2%) GO:0003700 (20.2%) GO:0005524 (20.2%)" membrane (19%) "phosphorelay sensor kinase activity (20.2%) DNA-binding transcription factor activity (20.2%) ATP binding (20.2%)" "IPR001789 (6.6%) IPR003594 (6.6%) IPR003661 (6.6%)" "Signal transduction response regulator, receiver domain (6.6%) Histidine kinase/HSP90-like ATPase domain (6.6%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.6%)" LGMHLHGLAGDLAAK Pseudomonadati Bacteria Pseudomonadati "4.2.1.136 (50.8%) 5.1.99.6 (49.2%)" "ADP-dependent NAD(P)H-hydrate dehydratase (50.8%) NAD(P)H-hydrate epimerase (49.2%)" "GO:0046496 (16.6%) GO:0110051 (16.6%)" "GO:0005524 (17.1%) GO:0052855 (16.6%) GO:0052856 (16.6%)" "nicotinamide nucleotide metabolic process (16.6%) metabolite repair (16.6%)" "ATP binding (17.1%) ADP-dependent NAD(P)H-hydrate dehydratase activity (16.6%) NAD(P)HX epimerase activity (16.6%)" "IPR000631 (17.3%) IPR029056 (17.3%) IPR017953 (16.8%)" "ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase (17.3%) Ribokinase-like (17.3%) Carbohydrate kinase, predicted, conserved site (16.8%)" LDLPELPELMLDNTDRNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (49.6%) GO:0004356 (50.4%) glutamine biosynthetic process (49.6%) glutamine synthetase activity (50.4%) "IPR008146 (14.5%) IPR027303 (14.5%) IPR040577 (14.5%)" "Glutamine synthetase, catalytic domain (14.5%) Glutamine synthetase, glycine-rich site (14.5%) Glutamine synthetase, C-terminal (14.5%)" TSLAVEVTNNPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.6.1.- (76.5%) 2.6.1.11 (23.5%)" "Transaminases (76.5%) acetylornithine transaminase (23.5%)" "GO:0030170 (33.1%) GO:0042802 (33.1%) GO:0008483 (32.6%)" "pyridoxal phosphate binding (33.1%) identical protein binding (33.1%) transaminase activity (32.6%)" "IPR005814 (16.8%) IPR050103 (16.8%) IPR015421 (16.6%)" "Aminotransferase class-III (16.8%) Class-III Pyridoxal-phosphate-dependent Aminotransferase (16.8%) Pyridoxal phosphate-dependent transferase, major domain (16.6%)" KQFDNYTMAQDVYNVTADQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" ECPLTFR root GO:0016020 (87.1%) GO:0016787 (12.9%) membrane (87.1%) hydrolase activity (12.9%) "IPR052722 (16.9%) IPR003607 (16.7%) IPR006674 (16.7%)" "Cyclic-di-AMP phosphodiesterase PgpH (16.9%) HD/PDEase domain (16.7%) HD domain (16.7%)" ELHELLR root "1.4.1.13 (37.5%) 4.3.2.2 (17.3%) 1.1.5.3 (11%)" "glutamate synthase (NADPH) (37.5%) adenylosuccinate lyase (17.3%) glycerol-3-phosphate dehydrogenase (11%)" "GO:0006351 (3.7%) GO:0019079 (3.6%) GO:0006537 (2.9%)" "GO:0005737 (3.2%) GO:0005829 (2.5%) GO:0005912 (1.8%)" "GO:0003723 (3.9%) GO:0046872 (3.8%) GO:0003968 (3.6%)" "DNA-templated transcription (3.7%) viral genome replication (3.6%) glutamate biosynthetic process (2.9%)" "cytoplasm (3.2%) cytosol (2.5%) adherens junction (1.8%)" "RNA binding (3.9%) metal ion binding (3.8%) RNA-directed RNA polymerase activity (3.6%)" "IPR028243 (3.4%) IPR004897 (2.8%) IPR016075 (2.8%)" "Paramyxovirus structural protein P/V, N-terminal domain (3.4%) P/V phosphoprotein, paramyxoviral (2.8%) RNA polymerase, phosphoprotein P, C-terminal XD, paramyxovirinae (2.8%)" DSVPEELDELTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0034605 (19%) GO:0042026 (18.1%) GO:0006508 (3%)" GO:0005737 (19%) "GO:0005524 (19%) GO:0016887 (19%) GO:0008233 (3%)" "cellular response to heat (19%) protein refolding (18.1%) proteolysis (3%)" cytoplasm (19%) "ATP binding (19%) ATP hydrolysis activity (19%) peptidase activity (3%)" "IPR018368 (8.5%) IPR041546 (8.5%) IPR050130 (8.5%)" "ClpA/B, conserved site 1 (8.5%) ClpA/ClpB, AAA lid domain (8.5%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.5%)" NVNDVPAGEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SFVSLEYQNVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006629 (50%) GO:0016746 (50%) lipid metabolic process (50%) acyltransferase activity (50%) "IPR052351 (51.6%) IPR016181 (48.4%)" "L-ornithine N(alpha)-acyltransferase (51.6%) Acyl-CoA N-acyltransferase (48.4%)" KLNLTLDGETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GHGGWMVDLSLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) TLLNDLR root "2.7.11.25 (78.5%) 2.3.2.31 (1.7%) 4.2.2.29 (1.5%)" "mitogen-activated protein kinase kinase kinase (78.5%) RBR-type E3 ubiquitin transferase (1.7%) peptidoglycan lytic transglycosylase (1.5%)" "GO:0033554 (12.2%) GO:0006508 (1%) GO:0007015 (0.4%)" "GO:0016020 (2.5%) GO:0005737 (2.5%) GO:0005886 (1.2%)" "GO:0005524 (15.2%) GO:0046872 (14%) GO:0004709 (12.7%)" "cellular response to stress (12.2%) proteolysis (1%) actin filament organization (0.4%)" "membrane (2.5%) cytoplasm (2.5%) plasma membrane (1.2%)" "ATP binding (15.2%) metal ion binding (14%) MAP kinase kinase kinase activity (12.7%)" "IPR000719 (7.1%) IPR025136 (7.1%) IPR011009 (7.1%)" "Protein kinase domain (7.1%) MAP3K, TRAFs-binding domain (7.1%) Protein kinase-like domain superfamily (7.1%)" KWGYFPAAAFAWK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.5%) IPR023996 (13.5%) IPR039426 (13.5%)" "TonB-dependent receptor-like, beta-barrel (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent receptor-like (13.5%)" LYLFDTTLRDGEQVPGCQLNTVEK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.2%) GO:0005737 (19.7%) "GO:0003852 (20.2%) GO:0003985 (19.7%) GO:0030145 (19.7%)" L-leucine biosynthetic process (20.2%) cytoplasm (19.7%) "2-isopropylmalate synthase activity (20.2%) acetyl-CoA C-acetyltransferase activity (19.7%) manganese ion binding (19.7%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" MADGSEVSYTTDQLPDAPVTVSPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (32%) GO:0009279 (36%) GO:0015344 (32%) siderophore transmembrane transport (32%) cell outer membrane (36%) siderophore uptake transmembrane transporter activity (32%) "IPR057601 (24.3%) IPR036942 (21.6%) IPR039426 (21.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (24.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (21.6%) TonB-dependent receptor-like (21.6%)" ADKDWATSDQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.16 (100%) cysteine--tRNA ligase (100%) GO:0006423 (20.3%) GO:0005829 (20.3%) "GO:0004817 (20.3%) GO:0005524 (20.3%) GO:0008270 (17.6%)" cysteinyl-tRNA aminoacylation (20.3%) cytosol (20.3%) "cysteine-tRNA ligase activity (20.3%) ATP binding (20.3%) zinc ion binding (17.6%)" "IPR009080 (15%) IPR015273 (15%) IPR024909 (15%)" "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (15%) Cysteinyl-tRNA synthetase, class Ia, DALR (15%) Cysteinyl-tRNA synthetase/mycothiol ligase (15%)" NELLWENSMNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (21.9%) IPR003385 (21.9%) IPR013783 (18.8%)" "Carbohydrate binding module family 20 (21.9%) Glycoside hydrolase, family 77 (21.9%) Immunoglobulin-like fold (18.8%)" DLTDCYLASGNGPGLSYHHGGFFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006281 (25.6%) GO:0016020 (23.3%) "GO:0004519 (25.6%) GO:0016787 (23.3%) GO:0004527 (2.3%)" DNA repair (25.6%) membrane (23.3%) "endonuclease activity (25.6%) hydrolase activity (23.3%) exonuclease activity (2.3%)" "IPR005135 (33.8%) IPR051547 (33.8%) IPR036691 (32.3%)" "Endonuclease/exonuclease/phosphatase (33.8%) Tyrosyl-DNA phosphodiesterase 2-like (33.8%) Endonuclease/exonuclease/phosphatase superfamily (32.3%)" SVDPSLDR root "2.7.11.1 (33.3%) 2.7.13.3 (33.3%) 6.1.1.19 (33.3%)" "non-specific serine/threonine protein kinase (33.3%) histidine kinase (33.3%) arginine--tRNA ligase (33.3%)" "GO:0015031 (17.1%) GO:0055085 (17.1%) GO:0015891 (12.3%)" "GO:0098797 (16.8%) GO:0030288 (12.3%) GO:0005737 (0.7%)" "GO:0031992 (16.8%) GO:0005524 (1.4%) GO:0003824 (0.7%)" "protein transport (17.1%) transmembrane transport (17.1%) siderophore transport (12.3%)" "plasma membrane protein complex (16.8%) outer membrane-bounded periplasmic space (12.3%) cytoplasm (0.7%)" "energy transducer activity (16.8%) ATP binding (1.4%) catalytic activity (0.7%)" "IPR006260 (21.7%) IPR037682 (21.7%) IPR051045 (21.3%)" "TonB/TolA, C-terminal (21.7%) TonB, C-terminal (21.7%) TonB-dependent transporter energy transducer (21.3%)" LLFSLSSK root "2.7.7.18 (38.5%) 2.7.11.1 (24.6%) 2.7.13.3 (16.9%)" "nicotinate-nucleotide adenylyltransferase (38.5%) non-specific serine/threonine protein kinase (24.6%) histidine kinase (16.9%)" "GO:0009435 (4.4%) GO:0019236 (1.4%) GO:0006281 (1.2%)" "GO:0005737 (13.5%) GO:0005886 (7.9%) GO:0016020 (3.4%)" "GO:0005524 (7.3%) GO:0070566 (4.4%) GO:0004674 (3.4%)" "NAD+ biosynthetic process (4.4%) response to pheromone (1.4%) DNA repair (1.2%)" "cytoplasm (13.5%) plasma membrane (7.9%) membrane (3.4%)" "ATP binding (7.3%) adenylyltransferase activity (4.4%) protein serine/threonine kinase activity (3.4%)" "IPR001680 (7.1%) IPR049916 (7%) IPR015943 (6.8%)" "WD40 repeat (7.1%) WD repeat-containing protein 72-like (7%) WD40/YVTN repeat-like-containing domain superfamily (6.8%)" LLSDSDFPLEDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.6.- (100%) Sulfuric ester hydrolases (100%) "GO:0005886 (36.3%) GO:0016020 (2.5%)" "GO:0046872 (33.8%) GO:0016787 (25%) GO:0016740 (2.5%)" "plasma membrane (36.3%) membrane (2.5%)" "metal ion binding (33.8%) hydrolase activity (25%) transferase activity (2.5%)" "IPR000917 (25.8%) IPR050448 (25.8%) IPR012160 (24.2%)" "Sulfatase, N-terminal (25.8%) OpgB/LTA synthase bacterial cell wall biosynthesis (25.8%) Lipoteichoic acid synthase-like (24.2%)" WNLVNVNKPSLDYATGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LDHMFDYLPYDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR039448 (34.3%) IPR011050 (32.4%) IPR012334 (32.4%)" "Right handed beta helix domain (34.3%) Pectin lyase fold/virulence factor (32.4%) Pectin lyase fold (32.4%)" FLEGNNLFSDLKLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" LAGLMLNLEDLLHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016740 (100%) transferase activity (100%) "IPR041633 (33.3%) IPR043519 (33.3%) IPR052038 (33.3%)" "Polymerase beta, nucleotidyltransferase (33.3%) Nucleotidyltransferase superfamily (33.3%) Type VII TA system antitoxin (33.3%)" GLLDLDANVDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TLGNGYPFTQVPFTSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.2%) "GO:0016787 (49.2%) GO:0016798 (1.6%)" carbohydrate metabolic process (49.2%) "hydrolase activity (49.2%) hydrolase activity, acting on glycosyl bonds (1.6%)" "IPR012878 (17%) IPR049046 (17%) IPR049049 (17%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17%)" VENPTVTNLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019346 (20.4%) GO:0005737 (20.4%) "GO:0016846 (20.4%) GO:0030170 (20.4%) GO:0016740 (12.7%)" transsulfuration (20.4%) cytoplasm (20.4%) "carbon-sulfur lyase activity (20.4%) pyridoxal phosphate binding (20.4%) transferase activity (12.7%)" "IPR000277 (25.4%) IPR015421 (25.4%) IPR015424 (25.4%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (25.4%) Pyridoxal phosphate-dependent transferase, major domain (25.4%) Pyridoxal phosphate-dependent transferase (25.4%)" YLVDFLR root "2.3.1.129 (28.7%) 3.5.1.1 (13.8%) 4.3.2.1 (6.4%)" "acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (28.7%) asparaginase (13.8%) argininosuccinate lyase (6.4%)" "GO:0009245 (2.5%) GO:0007018 (2%) GO:0006520 (1.3%)" "GO:0016020 (6.9%) GO:0005737 (4%) GO:0005886 (3.5%)" "GO:0005524 (5.7%) GO:0016787 (4.6%) GO:0004518 (3%)" "lipid A biosynthetic process (2.5%) microtubule-based movement (2%) amino acid metabolic process (1.3%)" "membrane (6.9%) cytoplasm (4%) plasma membrane (3.5%)" "ATP binding (5.7%) hydrolase activity (4.6%) nuclease activity (3%)" "IPR027417 (3.6%) IPR029058 (3.4%) IPR009656 (2.9%)" "P-loop containing nucleoside triphosphate hydrolase (3.6%) Alpha/Beta hydrolase fold (3.4%) PHB de-polymerase, C-terminal (2.9%)" TLGNVTLDCQTLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) AMFTAAVR root 2.7.1.40 (100%) pyruvate kinase (100%) "GO:0016020 (2%) GO:0005576 (1%) GO:0005783 (1%)" "GO:0004743 (19.4%) GO:0016301 (19.4%) GO:0000287 (18.4%)" "membrane (2%) extracellular region (1%) endoplasmic reticulum (1%)" "pyruvate kinase activity (19.4%) kinase activity (19.4%) magnesium ion binding (18.4%)" "IPR015795 (11.3%) IPR036918 (11.3%) IPR001697 (10.7%)" "Pyruvate kinase, C-terminal (11.3%) Pyruvate kinase, C-terminal domain superfamily (11.3%) Pyruvate kinase (10.7%)" GEAYDEEELAKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (15.5%) GO:0008360 (12.7%) GO:0009252 (12.7%)" GO:0005737 (12.7%) "GO:0005524 (15.5%) GO:0008716 (15.5%) GO:0046872 (15.5%)" "cell wall organization (15.5%) regulation of cell shape (12.7%) peptidoglycan biosynthetic process (12.7%)" cytoplasm (12.7%) "ATP binding (15.5%) D-alanine-D-alanine ligase activity (15.5%) metal ion binding (15.5%)" "IPR000291 (14.7%) IPR005905 (14.7%) IPR011095 (14.7%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.7%) D-alanine--D-alanine ligase (14.7%) D-alanine--D-alanine ligase, C-terminal (14.7%)" NWGMEFTVGYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EVWALGPR Bacteria Bacteria GO:0005886 (100%) plasma membrane (100%) "IPR003688 (33.3%) IPR027417 (33.3%) IPR051539 (33.3%)" "Type IV secretion system protein TraG/VirD4 (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) Type IV secretion system-coupling protein (33.3%)" AQVSLLAASPAFAAGTNVDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LDVAMSGR root "3.2.1.22 (99.4%) 7.6.2.2 (0.6%)" "alpha-galactosidase (99.4%) ABC-type xenobiotic transporter (0.6%)" "GO:0016052 (45.7%) GO:0090374 (0.6%) GO:0000272 (0.3%)" "GO:0005737 (0.6%) GO:0005743 (0.6%)" "GO:0004557 (46%) GO:0016788 (3.6%) GO:0005524 (0.6%)" "carbohydrate catabolic process (45.7%) oligopeptide export from mitochondrion (0.6%) polysaccharide catabolic process (0.3%)" "cytoplasm (0.6%) mitochondrial inner membrane (0.6%)" "alpha-galactosidase activity (46%) hydrolase activity, acting on ester bonds (3.6%) ATP binding (0.6%)" "IPR031705 (12.4%) IPR013780 (12.2%) IPR017853 (12.2%)" "Glycosyl hydrolase family 36, C-terminal (12.4%) Glycosyl hydrolase, all-beta (12.2%) Glycoside hydrolase superfamily (12.2%)" EELLDYATR root IPR021527 (100%) Protein of unknown function DUF2795 (100%) KGGNLLFVTPTQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR008979 (25%) IPR013830 (25%) IPR036514 (25%)" "Galactose-binding-like domain superfamily (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" SGHTEAALDLCK Pseudomonadati Bacteria Pseudomonadati "4.1.99.12 (50.7%) 3.5.4.25 (49.3%)" "3,4-dihydroxy-2-butanone-4-phosphate synthase (50.7%) GTP cyclohydrolase II (49.3%)" GO:0009231 (12.6%) GO:0005829 (12.6%) "GO:0003935 (12.6%) GO:0008686 (12.6%) GO:0000287 (12.3%)" riboflavin biosynthetic process (12.6%) cytosol (12.6%) "GTP cyclohydrolase II activity (12.6%) 3,4-dihydroxy-2-butanone-4-phosphate synthase activity (12.6%) magnesium ion binding (12.3%)" "IPR000422 (16.8%) IPR017945 (16.8%) IPR032677 (16.8%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.8%) DHBP synthase RibB-like alpha/beta domain superfamily (16.8%) GTP cyclohydrolase II (16.8%)" LQFDLQLK root "3.1.4.52 (50%) 3.5.1.28 (50%)" "cyclic-guanylate-specific phosphodiesterase (50%) N-acetylmuramoyl-L-alanine amidase (50%)" "GO:0006526 (7.1%) GO:0006508 (3.6%) GO:0009253 (3.6%)" "GO:0009279 (32.1%) GO:0016020 (10.7%) GO:0030288 (3.6%)" "GO:0071111 (10.7%) GO:0008777 (7.1%) GO:0046872 (7.1%)" "L-arginine biosynthetic process (7.1%) proteolysis (3.6%) peptidoglycan catabolic process (3.6%)" "cell outer membrane (32.1%) membrane (10.7%) outer membrane-bounded periplasmic space (3.6%)" "cyclic-guanylate-specific phosphodiesterase activity (10.7%) acetylornithine deacetylase activity (7.1%) metal ion binding (7.1%)" "IPR008969 (8.4%) IPR012910 (8.4%) IPR023996 (8.4%)" "Carboxypeptidase-like, regulatory domain superfamily (8.4%) TonB-dependent receptor, plug domain (8.4%) TonB-dependent outer membrane protein, SusC/RagA (8.4%)" TQECDVLLALGMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR012000 (13.1%) IPR045229 (13.1%) IPR011766 (12.7%)" "Thiamine pyrophosphate enzyme, central domain (13.1%) Thiamine pyrophosphate enzyme (13.1%) Thiamine pyrophosphate enzyme, TPP-binding (12.7%)" KAGNFVLLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) GO:0006221 (2.2%) "GO:0016491 (46.7%) GO:0051536 (43.3%) GO:0046872 (2.2%)" pyrimidine nucleotide biosynthetic process (2.2%) "oxidoreductase activity (46.7%) iron-sulfur cluster binding (43.3%) metal ion binding (2.2%)" "IPR017927 (11.4%) IPR017938 (11.1%) IPR019480 (11.1%)" "FAD-binding domain, ferredoxin reductase-type (11.4%) Riboflavin synthase-like beta-barrel (11.1%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.1%)" FDTPVSHNLMQGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (19.6%) GO:0043952 (19.6%) GO:0065002 (19.6%)" GO:0005886 (20.2%) GO:0015450 (20.2%) "protein targeting (19.6%) protein transport by the Sec complex (19.6%) intracellular protein transmembrane transport (19.6%)" plasma membrane (20.2%) protein-transporting ATPase activity (20.2%) "IPR005791 (11.3%) IPR022646 (11.3%) IPR022813 (11.3%)" "Protein translocase subunit SecD (11.3%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.3%) Protein-export membrane protein SecD/SecF, archaeal and bacterial (11.3%)" SEACENLEQAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (96.3%) 6.3.4.16 (3.7%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (96.3%) carbamoyl-phosphate synthase (ammonia) (3.7%)" "GO:0006541 (13.8%) GO:0006221 (12.4%) GO:0006526 (12.4%)" GO:0005737 (13.8%) "GO:0004088 (13.8%) GO:0005524 (13.8%) GO:0046872 (13.8%)" "glutamine metabolic process (13.8%) pyrimidine nucleotide biosynthetic process (12.4%) L-arginine biosynthetic process (12.4%)" cytoplasm (13.8%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.8%) ATP binding (13.8%) metal ion binding (13.8%)" "IPR005479 (10.5%) IPR005480 (10.5%) IPR011761 (10.5%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.5%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.5%) ATP-grasp fold (10.5%)" NYLVTSGLHVGDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" VETEWLAMPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006814 (33.3%) GO:0016020 (33.3%) GO:0015297 (33.3%) sodium ion transport (33.3%) membrane (33.3%) antiporter activity (33.3%) "IPR004680 (50%) IPR045016 (50%)" "Citrate transporter-like domain (50%) Na(+)/H(+) antiporter NhaD-like (50%)" GQLLATLNPTTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" VKNQLDGAYVEVSTAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.2%) GO:0005829 (20.2%) "GO:0003994 (20.2%) GO:0051539 (20.2%) GO:0046872 (19%)" tricarboxylic acid cycle (20.2%) cytosol (20.2%) "aconitate hydratase activity (20.2%) 4 iron, 4 sulfur cluster binding (20.2%) metal ion binding (19%)" "IPR000573 (11.6%) IPR050926 (11.6%) IPR001030 (11.2%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.6%) Aconitase/IPM Isomerase (11.6%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.2%)" YETESSGGLTYDTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.19 (100%) nicotinate-nucleotide diphosphorylase (carboxylating) (100%) "GO:0009435 (25%) GO:0034213 (25%)" GO:0005737 (25%) GO:0004514 (25%) "NAD+ biosynthetic process (25%) quinolinate catabolic process (25%)" cytoplasm (25%) nicotinate-nucleotide diphosphorylase (carboxylating) activity (25%) "IPR002638 (14.6%) IPR004393 (14.6%) IPR022412 (14.6%)" "Quinolinate phosphoribosyl transferase, C-terminal (14.6%) Nicotinate-nucleotide pyrophosphorylase (14.6%) Quinolinate phosphoribosyl transferase, N-terminal (14.6%)" MGEDKGLVMDGR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (19%) GO:0015949 (19%)" GO:0005829 (19%) "GO:0005524 (19%) GO:0036431 (19%) GO:0036430 (4.9%)" "pyrimidine nucleotide metabolic process (19%) nucleobase-containing small molecule interconversion (19%)" cytosol (19%) "ATP binding (19%) dCMP kinase activity (19%) CMP kinase activity (4.9%)" "IPR003136 (33.3%) IPR011994 (33.3%) IPR027417 (33.3%)" "Cytidylate kinase (33.3%) Cytidylate kinase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" GQDGLVLCPGFGQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (11.9%) GO:0044210 (11.9%)" "GO:0005829 (11.9%) GO:0097268 (11.7%)" "GO:0003883 (11.9%) GO:0005524 (11.9%) GO:0042802 (11.9%)" "pyrimidine nucleobase biosynthetic process (11.9%) 'de novo' CTP biosynthetic process (11.9%)" "cytosol (11.9%) cytoophidium (11.7%)" "CTP synthase activity (11.9%) ATP binding (11.9%) identical protein binding (11.9%)" "IPR004468 (16.9%) IPR017926 (16.9%) IPR017456 (16.6%)" "CTP synthase (16.9%) Glutamine amidotransferase (16.9%) CTP synthase, N-terminal (16.6%)" LSLLNASHTLLSYPSFLGGYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.57 (100%) fructuronate reductase (100%) GO:0019594 (49%) "GO:0016616 (49%) GO:0008866 (2%)" mannitol metabolic process (49%) "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (49%) fructuronate reductase activity (2%)" "IPR013118 (13.3%) IPR050988 (13.3%) IPR013131 (12.8%)" "Mannitol dehydrogenase, C-terminal (13.3%) Mannitol Dehydrogenase/Oxidoreductase (13.3%) Mannitol dehydrogenase, N-terminal (12.8%)" DGEWLETDPLSLHKPLTYPNLGPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.5.1.7 (100%) saccharopine dehydrogenase (NAD(+), L-lysine-forming) (100%) GO:0004754 (100%) saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (100%) "IPR005097 (33.3%) IPR032095 (33.3%) IPR036291 (33.3%)" "Saccharopine dehydrogenase, NADP binding domain (33.3%) Saccharopine dehydrogenase-like, C-terminal (33.3%) NAD(P)-binding domain superfamily (33.3%)" APTCPSCGVELAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR025874 (94.4%) IPR011990 (5.6%)" "Double zinc ribbon (94.4%) Tetratricopeptide-like helical domain superfamily (5.6%)" KVQTFTVTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (16.7%) GO:0007165 (16.7%)" "GO:0016020 (16.7%) GO:0030288 (16.7%)" "GO:0004175 (16.7%) GO:0008236 (16.7%)" "proteolysis (16.7%) signal transduction (16.7%)" "membrane (16.7%) outer membrane-bounded periplasmic space (16.7%)" "endopeptidase activity (16.7%) serine-type peptidase activity (16.7%)" "IPR001478 (20%) IPR004447 (20%) IPR005151 (20%)" "PDZ domain (20%) C-terminal-processing peptidase S41A (20%) Tail specific protease (20%)" AYSMANYPDEGDLLTLTVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.9%) "GO:0005886 (16.2%) GO:0016020 (0.7%)" "GO:0016655 (16.9%) GO:0051537 (16.9%) GO:0009055 (16.2%)" sodium ion transport (16.9%) "plasma membrane (16.2%) membrane (0.7%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.9%) 2 iron, 2 sulfur cluster binding (16.9%) electron transfer activity (16.2%)" "IPR001433 (10.1%) IPR001709 (10.1%) IPR008333 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" EYWDLLR root "3.2.1.23 (98%) 2.4.3.3 (0.6%) 2.3.1.137 (0.3%)" "beta-galactosidase (98%) alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (0.6%) carnitine O-octanoyltransferase (0.3%)" "GO:0005990 (21.7%) GO:0006633 (1.4%) GO:0071770 (0.8%)" "GO:0009341 (21.7%) GO:0005737 (0.9%) GO:0005886 (0.7%)" "GO:0004565 (21.7%) GO:0030246 (21.2%) GO:0004312 (1.3%)" "lactose catabolic process (21.7%) fatty acid biosynthetic process (1.4%) DIM/DIP cell wall layer assembly (0.8%)" "beta-galactosidase complex (21.7%) cytoplasm (0.9%) plasma membrane (0.7%)" "beta-galactosidase activity (21.7%) carbohydrate binding (21.2%) fatty acid synthase activity (1.3%)" "IPR006103 (6.5%) IPR050347 (6.5%) IPR017853 (6.4%)" "Glycoside hydrolase family 2, catalytic domain (6.5%) Bacterial Beta-galactosidase (6.5%) Glycoside hydrolase superfamily (6.4%)" ETDKNYLMEVAAPGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (35.7%) IPR031107 (35.7%) IPR008978 (28.6%)" "Alpha crystallin/Hsp20 domain (35.7%) Small heat shock protein (35.7%) HSP20-like chaperone (28.6%)" LWVSTYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.6%) "GO:0000155 (26.2%) GO:0003700 (24.6%) GO:0043565 (24.6%)" membrane (24.6%) "phosphorelay sensor kinase activity (26.2%) DNA-binding transcription factor activity (24.6%) sequence-specific DNA binding (24.6%)" "IPR011110 (15.5%) IPR015943 (15.1%) IPR011123 (14.2%)" "Two component regulator propeller (15.5%) WD40/YVTN repeat-like-containing domain superfamily (15.1%) Two component regulator three Y (14.2%)" EHQELCNQLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009279 (94.6%) GO:0016020 (5.4%)" "cell outer membrane (94.6%) membrane (5.4%)" "IPR006665 (14.3%) IPR011659 (14.3%) IPR050330 (14.3%)" "OmpA-like domain (14.3%) WD40-like beta-propeller (14.3%) Bacterial Outer Membrane Structural/Functional (14.3%)" YDFTVYGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.2%) GO:0046556 (50.8%) L-arabinose metabolic process (49.2%) alpha-L-arabinofuranosidase activity (50.8%) "IPR003305 (17.1%) IPR051563 (17.1%) IPR010720 (16.6%)" "Carbohydrate-binding, CenC-like (17.1%) Glycosyl Hydrolase Family 51 (17.1%) Alpha-L-arabinofuranosidase, C-terminal (16.6%)" LLYLFGK root "2.7.7.7 (26.3%) 5.6.2.4 (22.5%) 3.6.4.12 (11.3%)" "DNA-directed DNA polymerase (26.3%) DNA 3'-5' helicase (22.5%) DNA helicase (11.3%)" "GO:0006281 (1.8%) GO:0000289 (1.6%) GO:0017148 (1.6%)" "GO:0005886 (10.6%) GO:0016020 (10.5%) GO:0005634 (2%)" "GO:0003677 (3.5%) GO:0005524 (3.2%) GO:0022857 (2.8%)" "DNA repair (1.8%) nuclear-transcribed mRNA poly(A) tail shortening (1.6%) negative regulation of translation (1.6%)" "plasma membrane (10.6%) membrane (10.5%) nucleus (2%)" "DNA binding (3.5%) ATP binding (3.2%) transmembrane transporter activity (2.8%)" "IPR027417 (2.3%) IPR000515 (1.6%) IPR035906 (1.6%)" "P-loop containing nucleoside triphosphate hydrolase (2.3%) ABC transporter type 1, transmembrane domain MetI-like (1.6%) MetI-like superfamily (1.6%)" GANALLFADLLEQYRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR016181 (50%) IPR039968 (50%)" "Acyl-CoA N-acyltransferase (50%) Bacterial ceramide synthase-like (50%)" NYFFAPHYPMNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) KQGVQLAHLAAGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.1.3.- (50%) 5.1.3.14 (50%)" "Acting on carbohydrates and derivatives (50%) UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) (50%)" "GO:0016853 (96.2%) GO:0008761 (3.8%)" "isomerase activity (96.2%) UDP-N-acetylglucosamine 2-epimerase activity (3.8%)" "IPR003331 (50%) IPR029767 (50%)" "UDP-N-acetylglucosamine 2-epimerase domain (50%) UDP-N-acetylglucosamine 2-epimerase WecB-like (50%)" LAELLCLGR root 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (16%) "GO:0000155 (26%) GO:0003700 (26%) GO:0043565 (26%)" membrane (16%) "phosphorelay sensor kinase activity (26%) DNA-binding transcription factor activity (26%) sequence-specific DNA binding (26%)" "IPR009057 (6.5%) IPR001789 (6%) IPR003594 (6%)" "Homedomain-like superfamily (6.5%) Signal transduction response regulator, receiver domain (6%) Histidine kinase/HSP90-like ATPase domain (6%)" ELKELGVEK Bacteria Bacteria "7.2.2.12 (90.2%) 2.4.2.3 (2.4%) 4.1.1.20 (2.4%)" "P-type Zn(2+) transporter (90.2%) uridine phosphorylase (2.4%) diaminopimelate decarboxylase (2.4%)" "GO:0009089 (0.8%) GO:0006428 (0.4%) GO:0009116 (0.4%)" "GO:0005886 (15.5%) GO:0005737 (0.4%) GO:0005829 (0.4%)" "GO:0005524 (15.5%) GO:0015086 (15.1%) GO:0016887 (15.1%)" "lysine biosynthetic process via diaminopimelate (0.8%) isoleucyl-tRNA aminoacylation (0.4%) nucleoside metabolic process (0.4%)" "plasma membrane (15.5%) cytoplasm (0.4%) cytosol (0.4%)" "ATP binding (15.5%) cadmium ion transmembrane transporter activity (15.1%) ATP hydrolysis activity (15.1%)" "IPR001757 (9.1%) IPR018303 (9.1%) IPR027256 (9.1%)" "P-type ATPase (9.1%) P-type ATPase, phosphorylation site (9.1%) P-type ATPase, subfamily IB (9.1%)" SLNLLEEPTEGK Bacteria Bacteria GO:0005886 (25.2%) "GO:0005524 (25.2%) GO:0016887 (25.2%) GO:0015424 (24.3%)" plasma membrane (25.2%) "ATP binding (25.2%) ATP hydrolysis activity (25.2%) ABC-type amino acid transporter activity (24.3%)" "IPR003439 (16.9%) IPR003593 (16.9%) IPR017871 (16.9%)" "ABC transporter-like, ATP-binding domain (16.9%) AAA+ ATPase domain (16.9%) ABC transporter-like, conserved site (16.9%)" TFYYSLTDDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20%) "GO:0000155 (20%) GO:0003700 (20%) GO:0005524 (20%)" membrane (20%) "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR011110 (8.5%) IPR015943 (8.5%) IPR001789 (6.4%)" "Two component regulator propeller (8.5%) WD40/YVTN repeat-like-containing domain superfamily (8.5%) Signal transduction response regulator, receiver domain (6.4%)" CWLMDDLCNELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.190 (96.4%) 2.1.1.- (3.6%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (96.4%) Methyltransferases (3.6%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR002792 (17%) IPR010280 (17%) IPR012340 (16.5%)" "TRAM domain (17%) (Uracil-5)-methyltransferase family (17%) Nucleic acid-binding, OB-fold (16.5%)" HNLSLQGGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.7%) IPR023996 (13.7%) IPR039426 (13.7%)" "TonB-dependent receptor-like, beta-barrel (13.7%) TonB-dependent outer membrane protein, SusC/RagA (13.7%) TonB-dependent receptor-like (13.7%)" MVEQANSYEYATFHNMMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.1%) IPR012910 (12.1%) IPR023996 (12.1%)" "Carboxypeptidase-like, regulatory domain superfamily (12.1%) TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein, SusC/RagA (12.1%)" ATLTEDFQVMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0003755 (96.9%) GO:0016853 (3.1%)" "peptidyl-prolyl cis-trans isomerase activity (96.9%) isomerase activity (3.1%)" "IPR000297 (25.4%) IPR050280 (25.4%) IPR027304 (23.8%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (25.4%) Outer Membrane Protein Chaperone SurA (25.4%) Trigger factor/SurA domain superfamily (23.8%)" FDKPQDSDLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (11.1%) GO:0008360 (11.1%) GO:0009252 (11.1%)" "GO:0005886 (11.1%) GO:0030288 (11.1%)" "GO:0004180 (11.1%) GO:0008658 (11.1%) GO:0008955 (11.1%)" "proteolysis (11.1%) regulation of cell shape (11.1%) peptidoglycan biosynthetic process (11.1%)" "plasma membrane (11.1%) outer membrane-bounded periplasmic space (11.1%)" "carboxypeptidase activity (11.1%) penicillin binding (11.1%) peptidoglycan glycosyltransferase activity (11.1%)" "IPR001264 (16.7%) IPR001460 (16.7%) IPR012338 (16.7%)" "Glycosyl transferase, family 51 (16.7%) Penicillin-binding protein, transpeptidase (16.7%) Beta-lactamase/transpeptidase-like (16.7%)" SLTTLLDNLESCGFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR027417 (34.1%) IPR036390 (34.1%) IPR011579 (31.8%)" "P-loop containing nucleoside triphosphate hydrolase (34.1%) Winged helix DNA-binding domain superfamily (34.1%) ATPase domain (31.8%)" NRPALGDSQSNVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006826 (10.9%) GO:0015889 (2.2%)" GO:0009279 (87%) "iron ion transport (10.9%) cobalamin transport (2.2%)" cell outer membrane (87%) "IPR012910 (13.8%) IPR023996 (13.8%) IPR023997 (13.8%)" "TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.8%)" LGDEVNPER root 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR002130 (25.5%) IPR020892 (25.5%) IPR044666 (25.5%)" "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain (25.5%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site (25.5%) Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like (25.5%)" LKELHTFEGMGHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0009409 (10%) GO:0010467 (10%) GO:0000027 (9.7%)" "GO:0005829 (10%) GO:1990904 (10%)" "GO:0005525 (10.3%) GO:0003924 (10%) GO:0000049 (9.7%)" "response to cold (10%) gene expression (10%) ribosomal large subunit assembly (9.7%)" "cytosol (10%) ribonucleoprotein complex (10%)" "GTP binding (10.3%) GTPase activity (10%) tRNA binding (9.7%)" "IPR004161 (7%) IPR000640 (6.8%) IPR009000 (6.8%)" "Translation elongation factor EFTu-like, domain 2 (7%) Elongation factor EFG, domain V-like (6.8%) Translation protein, beta-barrel domain superfamily (6.8%)" LTLEFTGAAPAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR008979 (25%) IPR013830 (25%) IPR036514 (25%)" "Galactose-binding-like domain superfamily (25%) SGNH hydrolase-type esterase domain (25%) SGNH hydrolase superfamily (25%)" SLLQAFLEPLDTLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.7%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.7%)" DENLLVPFR Bacteria Bacteria 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (25.4%) IPR043129 (25.4%) IPR050406 (25.4%)" "Carbohydrate kinase FGGY, N-terminal (25.4%) ATPase, nucleotide binding domain (25.4%) FGGY Carbohydrate Kinase (25.4%)" TAVENVELPLFYQGVSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.1%) IPR003593 (20.1%) IPR017871 (20.1%)" "ABC transporter-like, ATP-binding domain (20.1%) AAA+ ATPase domain (20.1%) ABC transporter-like, conserved site (20.1%)" LTDLDETAPDVEWQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" MSGVLDATSGSLSLLAHFANPEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" DDSLYNVGFLCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (56.5%) GO:0016787 (43.5%)" "acyltransferase activity, transferring groups other than amino-acyl groups (56.5%) hydrolase activity (43.5%)" "IPR003010 (21.5%) IPR000182 (20%) IPR001110 (20%)" "Carbon-nitrogen hydrolase (21.5%) GNAT domain (20%) Uncharacterised protein family UPF0012, conserved site (20%)" LLLYLEK root "4.4.1.13 (12.5%) 3.1.3.48 (8.7%) 2.3.2.27 (8.3%)" "cysteine-S-conjugate beta-lyase (12.5%) protein-tyrosine-phosphatase (8.7%) RING-type E3 ubiquitin transferase (8.3%)" "GO:0006957 (0.8%) GO:0006958 (0.8%) GO:0006904 (0.8%)" "GO:0016020 (5%) GO:0005615 (2.5%) GO:0005737 (2.2%)" "GO:0008270 (2.6%) GO:0003677 (2.6%) GO:0005524 (1.9%)" "complement activation, alternative pathway (0.8%) complement activation, classical pathway (0.8%) vesicle docking involved in exocytosis (0.8%)" "membrane (5%) extracellular space (2.5%) cytoplasm (2.2%)" "zinc ion binding (2.6%) DNA binding (2.6%) ATP binding (1.9%)" "IPR013783 (1.5%) IPR050473 (1.4%) IPR011626 (1.4%)" "Immunoglobulin-like fold (1.5%) Alpha-2-macroglobulin/Complement system (1.4%) Alpha-macroglobulin-like, TED domain (1.4%)" CTDAVLAALDEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0005975 (31.8%) GO:0006044 (31.8%)" "GO:0004342 (31.8%) GO:0016787 (3%) GO:0016853 (1.5%)" "carbohydrate metabolic process (31.8%) N-acetylglucosamine metabolic process (31.8%)" "glucosamine-6-phosphate deaminase activity (31.8%) hydrolase activity (3%) isomerase activity (1.5%)" "IPR052960 (18.5%) IPR024078 (18.1%) IPR003737 (17.4%)" "Glucosamine-6-phosphate deaminase-like (18.5%) Putative deacetylase LmbE-like domain superfamily (18.1%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (17.4%)" QFTLTLK root "5.2.1.8 (39.5%) 1.17.4.1 (28.9%) 2.7.11.1 (11.8%)" "peptidylprolyl isomerase (39.5%) ribonucleoside-diphosphate reductase (28.9%) non-specific serine/threonine protein kinase (11.8%)" "GO:0015031 (3.2%) GO:0051301 (3.2%) GO:0043335 (2.9%)" "GO:0005737 (6.5%) GO:0009279 (4.2%) GO:0016020 (4.2%)" "GO:0005524 (3.3%) GO:0003755 (3.1%) GO:0043022 (2.9%)" "protein transport (3.2%) cell division (3.2%) protein unfolding (2.9%)" "cytoplasm (6.5%) cell outer membrane (4.2%) membrane (4.2%)" "ATP binding (3.3%) peptidyl-prolyl cis-trans isomerase activity (3.1%) ribosome binding (2.9%)" "IPR023996 (2.5%) IPR012910 (2.5%) IPR023997 (2.5%)" "TonB-dependent outer membrane protein, SusC/RagA (2.5%) TonB-dependent receptor, plug domain (2.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (2.5%)" YLATLTVR root "GO:0006826 (6.3%) GO:0097696 (5.6%) GO:0070102 (3.5%)" "GO:0009279 (12.5%) GO:0005886 (4.9%) GO:0009897 (2.8%)" "GO:0004896 (4.2%) GO:0004915 (2.1%) GO:0019981 (2.1%)" "iron ion transport (6.3%) cell surface receptor signaling pathway via STAT (5.6%) interleukin-6-mediated signaling pathway (3.5%)" "cell outer membrane (12.5%) plasma membrane (4.9%) external side of plasma membrane (2.8%)" "cytokine receptor activity (4.2%) interleukin-6 receptor activity (2.1%) interleukin-6 binding (2.1%)" "IPR008969 (7.5%) IPR012910 (7.5%) IPR023996 (7.5%)" "Carboxypeptidase-like, regulatory domain superfamily (7.5%) TonB-dependent receptor, plug domain (7.5%) TonB-dependent outer membrane protein, SusC/RagA (7.5%)" GYKPFYLSHYGR Pseudomonadati Bacteria Pseudomonadati "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.1%) GO:0016787 (48.9%) membrane (51.1%) hydrolase activity (48.9%) "IPR000560 (50.7%) IPR029033 (49.3%)" "Histidine phosphatase superfamily, clade-2 (50.7%) Histidine phosphatase superfamily (49.3%)" ALQELALK root "3.2.1.21 (60.8%) 2.7.7.6 (5.9%) 1.2.1.3 (3.9%)" "beta-glucosidase (60.8%) DNA-directed RNA polymerase (5.9%) aldehyde dehydrogenase (NAD(+)) (3.9%)" "GO:0009251 (7.6%) GO:0006351 (0.7%) GO:0006508 (0.7%)" "GO:0042597 (7.6%) GO:0016020 (6.6%) GO:0005794 (2%)" "GO:0008422 (7.6%) GO:0005524 (2.9%) GO:0046872 (2.2%)" "glucan catabolic process (7.6%) DNA-templated transcription (0.7%) proteolysis (0.7%)" "periplasmic space (7.6%) membrane (6.6%) Golgi apparatus (2%)" "beta-glucosidase activity (7.6%) ATP binding (2.9%) metal ion binding (2.2%)" "IPR001764 (4.5%) IPR002772 (4.5%) IPR026891 (4.5%)" "Glycoside hydrolase, family 3, N-terminal (4.5%) Glycoside hydrolase family 3 C-terminal domain (4.5%) Fibronectin type III-like domain (4.5%)" FFDEEKPDAVVLAAAFVGGLMANSLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.271 (100%) GDP-L-fucose synthase (100%) GO:0042351 (23.1%) GO:0016020 (5.8%) "GO:0016853 (24%) GO:0050577 (24%) GO:0070401 (23.1%)" 'de novo' GDP-L-fucose biosynthetic process (23.1%) membrane (5.8%) "isomerase activity (24%) GDP-L-fucose synthase activity (24%) NADP+ binding (23.1%)" "IPR001509 (33.3%) IPR028614 (33.3%) IPR036291 (33.3%)" "NAD-dependent epimerase/dehydratase (33.3%) GDP-L-fucose synthase/GDP-L-colitose synthase (33.3%) NAD(P)-binding domain superfamily (33.3%)" SGGANEYLYDNFDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (75%) GO:0016787 (25%)" "acyltransferase activity, transferring groups other than amino-acyl groups (75%) hydrolase activity (25%)" "IPR000801 (20%) IPR013783 (20%) IPR014756 (20%)" "Esterase-like (20%) Immunoglobulin-like fold (20%) Immunoglobulin E-set (20%)" QLFSALGQVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.2.11 (100%) glutamate 5-kinase (100%) "GO:0055129 (22%) GO:0006561 (1%)" GO:0005829 (23%) "GO:0004349 (23%) GO:0005524 (23%) GO:0003723 (8%)" "L-proline biosynthetic process (22%) obsolete proline biosynthetic process (1%)" cytosol (23%) "glutamate 5-kinase activity (23%) ATP binding (23%) RNA binding (8%)" "IPR001048 (14.5%) IPR005715 (14.5%) IPR041739 (13.8%)" "Aspartate/glutamate/uridylate kinase (14.5%) Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase (14.5%) Glutamate-5-kinase domain (13.8%)" TPLTLLLTPLFTLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (0.7%) "GO:0000155 (24.8%) GO:0003700 (24.8%) GO:0005524 (24.8%)" membrane (0.7%) "phosphorelay sensor kinase activity (24.8%) DNA-binding transcription factor activity (24.8%) ATP binding (24.8%)" "IPR001789 (7.3%) IPR003594 (7.3%) IPR003661 (7.3%)" "Signal transduction response regulator, receiver domain (7.3%) Histidine kinase/HSP90-like ATPase domain (7.3%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.3%)" YYLSASYR root 3.1.4.11 (100%) phosphoinositide phospholipase C (100%) "GO:0007214 (10.1%) GO:0016042 (10.1%) GO:0032228 (10.1%)" "GO:0005737 (10.1%) GO:0009279 (7.7%) GO:0005765 (0.3%)" "GO:0004435 (10.1%) GO:0015344 (3%) GO:0003779 (0.3%)" "gamma-aminobutyric acid signaling pathway (10.1%) lipid catabolic process (10.1%) regulation of synaptic transmission, GABAergic (10.1%)" "cytoplasm (10.1%) cell outer membrane (7.7%) lysosomal membrane (0.3%)" "phosphatidylinositol-4,5-bisphosphate phospholipase C activity (10.1%) siderophore uptake transmembrane transporter activity (3%) actin binding (0.3%)" "IPR000008 (6.4%) IPR000909 (6.4%) IPR001192 (6.4%)" "C2 domain (6.4%) Phosphatidylinositol-specific phospholipase C, X domain (6.4%) Phosphoinositide phospholipase C family (6.4%)" LDSHLLYLGCTAQDLGALTAFLYCMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" AFASYDLR Bacteria Bacteria "IPR025631 (88.1%) IPR007963 (2.4%) IPR024191 (2.4%)" "Putative porin-10 (88.1%) Peptidase M61, catalytic domain (2.4%) Peptidase M61 (2.4%)" GQYNVCEHLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.14 (100%) L-iditol 2-dehydrogenase (100%) "GO:0016491 (47.6%) GO:0008270 (45.2%) GO:0046872 (4.8%)" "oxidoreductase activity (47.6%) zinc ion binding (45.2%) metal ion binding (4.8%)" "IPR011032 (17.2%) IPR013149 (17.2%) IPR013154 (17.2%)" "GroES-like superfamily (17.2%) Alcohol dehydrogenase-like, C-terminal (17.2%) Alcohol dehydrogenase-like, N-terminal (17.2%)" ALFNALANNSLDDLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (34.4%) IPR004134 (34.4%) IPR038765 (31.3%)" "Cysteine peptidase, cysteine active site (34.4%) Peptidase C1B, bleomycin hydrolase (34.4%) Papain-like cysteine peptidase superfamily (31.3%)" EMLNFQPQSQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002035 (34.4%) IPR002881 (34.4%) IPR036465 (31.3%)" "von Willebrand factor, type A (34.4%) Domain of unknown function DUF58 (34.4%) von Willebrand factor A-like domain superfamily (31.3%)" MLTDLELAK Bacteria Bacteria 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) GO:0035999 (31.4%) GO:0005737 (2.9%) "GO:0004329 (31.4%) GO:0005524 (31.4%) GO:0005507 (2.9%)" tetrahydrofolate interconversion (31.4%) cytoplasm (2.9%) "formate-tetrahydrofolate ligase activity (31.4%) ATP binding (31.4%) copper ion binding (2.9%)" "IPR000559 (32%) IPR020628 (32%) IPR027417 (30%)" "Formate-tetrahydrofolate ligase, FTHFS (32%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (32%) P-loop containing nucleoside triphosphate hydrolase (30%)" LNTLLVPQAFMDWSNQEFAPNQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) SLLVSTMQSYFEGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR018631 (35.1%) IPR012547 (33.3%) IPR027417 (31.6%)" "AAA-ATPase-like domain (35.1%) PD-(D/E)XK nuclease superfamily 9 (33.3%) P-loop containing nucleoside triphosphate hydrolase (31.6%)" AAEGNNFGTVLLPEGLLEFLPALKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.4%) GO:0006002 (13.7%)" GO:0005829 (14.4%) "GO:0003872 (14.4%) GO:0005524 (14.4%) GO:0046872 (14.4%)" "response to glucose (14.4%) fructose 6-phosphate metabolic process (13.7%)" cytosol (14.4%) "6-phosphofructokinase activity (14.4%) ATP binding (14.4%) metal ion binding (14.4%)" "IPR000023 (25.6%) IPR011183 (25.6%) IPR022953 (24.4%)" "Phosphofructokinase domain (25.6%) Pyrophosphate-dependent phosphofructokinase PfpB (25.6%) ATP-dependent 6-phosphofructokinase (24.4%)" YNNSVNTEYLGADSYTQDDEVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.7%) IPR012910 (20.7%) IPR008969 (19.6%)" "TonB-dependent receptor-like, beta-barrel (20.7%) TonB-dependent receptor, plug domain (20.7%) Carboxypeptidase-like, regulatory domain superfamily (19.6%)" EHLGGLYDYLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (46.1%) GO:0016887 (45.2%) GO:0016740 (7.8%)" "ATP binding (46.1%) ATP hydrolysis activity (45.2%) transferase activity (7.8%)" "IPR051309 (16.5%) IPR003439 (16.3%) IPR003593 (16.3%)" "ABC transporter ABCF subfamily ATPase (16.5%) ABC transporter-like, ATP-binding domain (16.3%) AAA+ ATPase domain (16.3%)" QDLVDLK root "4.1.1.33 (34.8%) 4.2.1.126 (12.9%) 1.2.7.1 (4.5%)" "diphosphomevalonate decarboxylase (34.8%) N-acetylmuramic acid 6-phosphate etherase (12.9%) pyruvate synthase (4.5%)" "GO:0035721 (2.2%) GO:0006979 (2%) GO:0015031 (2%)" "GO:0005737 (3%) GO:0005829 (2.6%) GO:0030991 (2%)" "GO:0005524 (2.5%) GO:0051539 (2.4%) GO:0005506 (2.3%)" "intraciliary retrograde transport (2.2%) response to oxidative stress (2%) protein transport (2%)" "cytoplasm (3%) cytosol (2.6%) intraciliary transport particle A (2%)" "ATP binding (2.5%) 4 iron, 4 sulfur cluster binding (2.4%) iron ion binding (2.3%)" "IPR015943 (2.2%) IPR001680 (2.1%) IPR017896 (2%)" "WD40/YVTN repeat-like-containing domain superfamily (2.2%) WD40 repeat (2.1%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (2%)" LHSVEVEGVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23.4%) "GO:0000155 (23.4%) GO:0003700 (23.4%) GO:0043565 (23.4%)" membrane (23.4%) "phosphorelay sensor kinase activity (23.4%) DNA-binding transcription factor activity (23.4%) sequence-specific DNA binding (23.4%)" "IPR001789 (6.5%) IPR003594 (6.5%) IPR003661 (6.5%)" "Signal transduction response regulator, receiver domain (6.5%) Histidine kinase/HSP90-like ATPase domain (6.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.5%)" LDVLKDASSTALYGSR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (1.6%) GO:0006826 (0.5%)" GO:0009279 (96.3%) GO:0015344 (1.6%) "siderophore transmembrane transport (1.6%) iron ion transport (0.5%)" cell outer membrane (96.3%) siderophore uptake transmembrane transporter activity (1.6%) "IPR023997 (13.1%) IPR039426 (13.1%) IPR012910 (13%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (13.1%) TonB-dependent receptor-like (13.1%) TonB-dependent receptor, plug domain (13%)" HDFFTENGCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (50%) IPR032466 (50%)" "Uronate isomerase (50%) Metal-dependent hydrolase (50%)" AQVSLLAASPAFAAGTNVDYKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NWSKPSSNQLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (23.6%) "GO:0000155 (23.6%) GO:0003700 (23.6%) GO:0043565 (23.6%)" membrane (23.6%) "phosphorelay sensor kinase activity (23.6%) DNA-binding transcription factor activity (23.6%) sequence-specific DNA binding (23.6%)" "IPR001789 (6.5%) IPR003594 (6.5%) IPR003661 (6.5%)" "Signal transduction response regulator, receiver domain (6.5%) Histidine kinase/HSP90-like ATPase domain (6.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.5%)" AFSTALFNSGASVGALAAPATLPLLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0015134 (50%) membrane (50%) hexuronate transmembrane transporter activity (50%) "IPR011701 (25.4%) IPR020846 (25.4%) IPR050382 (25.4%)" "Major facilitator superfamily (25.4%) Major facilitator superfamily domain (25.4%) Major Facilitator Superfamily Sodium/Anion Cotransporter (25.4%)" VLWYNSFLANHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (20%) "GO:0000155 (20%) GO:0003700 (20%) GO:0005524 (20%)" membrane (20%) "phosphorelay sensor kinase activity (20%) DNA-binding transcription factor activity (20%) ATP binding (20%)" "IPR011110 (7.3%) IPR001789 (6.7%) IPR003594 (6.7%)" "Two component regulator propeller (7.3%) Signal transduction response regulator, receiver domain (6.7%) Histidine kinase/HSP90-like ATPase domain (6.7%)" YTVDEVFYSYSGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021457 (100%) Protein of unknown function DUF3108 (100%) DLNAPVLLR root "4.1.1.19 (95%) 3.5.4.25 (5%)" "arginine decarboxylase (95%) GTP cyclohydrolase II (5%)" "GO:0006527 (19%) GO:0008295 (19%) GO:0033388 (17.1%)" "GO:0005737 (1%) GO:0005829 (1%)" "GO:0008792 (19%) GO:0046872 (17.1%) GO:0003935 (1%)" "L-arginine catabolic process (19%) spermidine biosynthetic process (19%) putrescine biosynthetic process from arginine (17.1%)" "cytoplasm (1%) cytosol (1%)" "arginine decarboxylase activity (19%) metal ion binding (17.1%) GTP cyclohydrolase II activity (1%)" "IPR002985 (11.4%) IPR022644 (11.4%) IPR022653 (11.4%)" "Arginine decarboxylase (11.4%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.4%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.4%)" LGTGYYRDEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR027890 (100%) Protein of unknown function DUF4491 (100%) LLAPLNDNGHVTYLPLNDLEAWEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030170 (33.3%) GO:0042802 (33.3%) GO:0008483 (32.2%)" "pyridoxal phosphate binding (33.3%) identical protein binding (33.3%) transaminase activity (32.2%)" "IPR005814 (16.9%) IPR049704 (16.9%) IPR050103 (16.9%)" "Aminotransferase class-III (16.9%) Aminotransferases class-III pyridoxal-phosphate attachment site (16.9%) Class-III Pyridoxal-phosphate-dependent Aminotransferase (16.9%)" GDYTLTPYTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" FSYTFAGNVVNDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.8%) GO:0009279 (36.4%) GO:0015344 (31.8%) siderophore transmembrane transport (31.8%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (31.8%) "IPR057601 (23.5%) IPR036942 (20.6%) IPR039426 (20.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (23.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.6%) TonB-dependent receptor-like (20.6%)" WGFMAGDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" SVLLDENYQLSAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.9 (100%) histidinol-phosphate transaminase (100%) GO:0000105 (33.3%) "GO:0004400 (33.3%) GO:0030170 (33.3%)" L-histidine biosynthetic process (33.3%) "histidinol-phosphate transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR001917 (16.7%) IPR004839 (16.7%) IPR005861 (16.7%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.7%) Aminotransferase, class I/classII, large domain (16.7%) Histidinol-phosphate aminotransferase family (16.7%)" VFNYTVFNSGSLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033985 (54.5%) IPR011990 (45.5%)" "SusD-like, N-terminal (54.5%) Tetratricopeptide-like helical domain superfamily (45.5%)" HNLTAMVGYEAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" APGSSLMPGK root "4.3.1.1 (92.8%) 4.2.1.2 (6%) 5.2.1.8 (1.2%)" "aspartate ammonia-lyase (92.8%) fumarate hydratase (6%) peptidylprolyl isomerase (1.2%)" "GO:0006531 (25%) GO:0006099 (23%) GO:0006106 (0.2%)" "GO:0005829 (25%) GO:0005737 (0.2%) GO:0016020 (0.2%)" "GO:0008797 (25%) GO:0003755 (0.2%) GO:0004175 (0.2%)" "aspartate metabolic process (25%) tricarboxylic acid cycle (23%) fumarate metabolic process (0.2%)" "cytosol (25%) cytoplasm (0.2%) membrane (0.2%)" "aspartate ammonia-lyase activity (25%) peptidyl-prolyl cis-trans isomerase activity (0.2%) endopeptidase activity (0.2%)" "IPR020557 (13.8%) IPR022761 (13.8%) IPR008948 (13.7%)" "Fumarate lyase, conserved site (13.8%) Fumarate lyase, N-terminal (13.8%) L-Aspartase-like (13.7%)" TTLNLNLGNTSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.4%) "GO:0003677 (25.4%) GO:0003917 (25.4%) GO:0046872 (23.9%)" DNA topological change (25.4%) "DNA binding (25.4%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.4%) metal ion binding (23.9%)" "IPR000380 (7.5%) IPR003602 (7.5%) IPR013497 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, DNA-binding domain (7.5%) DNA topoisomerase, type IA, central (7.5%)" YEELKDMLSDEPDLK Pseudomonadati Bacteria Pseudomonadati 1.1.1.267 (100%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (100%) GO:0051484 (23%) "GO:0030145 (23%) GO:0030604 (23%) GO:0070402 (23%)" isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process (23%) "manganese ion binding (23%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity (23%) NADPH binding (23%)" "IPR003821 (17.2%) IPR013512 (17.2%) IPR036291 (17.2%)" "1-deoxy-D-xylulose 5-phosphate reductoisomerase (17.2%) 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal (17.2%) NAD(P)-binding domain superfamily (17.2%)" YMGELMPLEDTGSFTNHCGVSDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.5%) IPR006584 (12.5%) IPR006710 (12.5%)" "Carbohydrate binding module family 6 (12.5%) Cellulose binding, type IV (12.5%) Glycoside hydrolase, family 43 (12.5%)" ETSWLPVLLLTAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (21.1%) "GO:0000155 (24.1%) GO:0003700 (24.1%) GO:0043565 (24.1%)" membrane (21.1%) "phosphorelay sensor kinase activity (24.1%) DNA-binding transcription factor activity (24.1%) sequence-specific DNA binding (24.1%)" "IPR001789 (6.5%) IPR003594 (6.5%) IPR003661 (6.5%)" "Signal transduction response regulator, receiver domain (6.5%) Histidine kinase/HSP90-like ATPase domain (6.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.5%)" LWDKHVVQLVPDGPTQLYLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.8%) IPR050067 (14.8%) IPR004430 (14.1%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.8%) Isopropylmalate dehydratase and related enzymes (14.8%) 3-isopropylmalate dehydratase, large subunit (14.1%)" DLETLMQLLYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (33.9%) "GO:0004222 (33.9%) GO:0046872 (32.2%)" proteolysis (33.9%) "metalloendopeptidase activity (33.9%) metal ion binding (32.2%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" DKFVEMDSEAFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.8%) IPR002301 (12.8%) IPR013155 (12.8%)" "Aminoacyl-tRNA synthetase, class Ia (12.8%) Isoleucine-tRNA ligase (12.8%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.8%)" SEYQFDGDSCGVLTALHEQSDDLNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004478 (16.7%) GO:0005524 (16.7%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) methionine adenosyltransferase activity (16.7%) ATP binding (16.7%)" "IPR002133 (16.8%) IPR022628 (16.8%) IPR022629 (16.8%)" "S-adenosylmethionine synthetase (16.8%) S-adenosylmethionine synthetase, N-terminal (16.8%) S-adenosylmethionine synthetase, central domain (16.8%)" RVEELHGDYLEYVYDLVDEDVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.5%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.5%) "IPR003284 (18.6%) IPR028994 (16.3%) IPR022045 (13.4%)" "Salmonella virulence plasmid 65kDa B protein (18.6%) Integrin alpha, N-terminal (16.3%) Insecticide toxin TcdB middle/N-terminal (13.4%)" EGDVLPNAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.26.11 (100%) ribonuclease Z (100%) "GO:0042781 (50%) GO:0008270 (48.4%) GO:0046872 (1.6%)" "3'-tRNA processing endoribonuclease activity (50%) zinc ion binding (48.4%) metal ion binding (1.6%)" "IPR001279 (34%) IPR013471 (34%) IPR036866 (31.9%)" "Metallo-beta-lactamase (34%) Ribonuclease Z/BN (34%) Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (31.9%)" FLYNPDLK root "2.7.11.1 (98%) 6.1.1.5 (2%)" "non-specific serine/threonine protein kinase (98%) isoleucine--tRNA ligase (2%)" "GO:0044773 (19.4%) GO:0006826 (3.6%) GO:0000082 (0.4%)" "GO:0005634 (19.4%) GO:0009279 (4.5%) GO:0000775 (0.4%)" "GO:0005524 (20.6%) GO:0004674 (19.8%) GO:0000049 (0.4%)" "mitotic DNA damage checkpoint signaling (19.4%) iron ion transport (3.6%) G1/S transition of mitotic cell cycle (0.4%)" "nucleus (19.4%) cell outer membrane (4.5%) chromosome, centromeric region (0.4%)" "ATP binding (20.6%) protein serine/threonine kinase activity (19.8%) tRNA binding (0.4%)" "IPR000719 (19%) IPR008271 (19%) IPR011009 (19%)" "Protein kinase domain (19%) Serine/threonine-protein kinase, active site (19%) Protein kinase-like domain superfamily (19%)" HLAALSGGQLQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.3%) IPR003593 (20.3%) IPR017871 (20.3%)" "ABC transporter-like, ATP-binding domain (20.3%) AAA+ ATPase domain (20.3%) ABC transporter-like, conserved site (20.3%)" AASLGCNALVGLDLDYETVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002765 (57.1%) IPR035439 (42.9%)" "Uncharacterised protein family UPF0145, YbjQ-like (57.1%) UPF0145 domain superfamily (42.9%)" ADHLVLNPLTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR045691 (100%) Protein of unknown function DUF6056 (100%) LFDERPEVENVTYTVYSPYELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) LHAEQLLDYLHQ Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.24 (100%) thioredoxin-dependent peroxiredoxin (100%) "GO:0034599 (25%) GO:0045454 (25%)" GO:0005737 (25%) GO:0008379 (25%) "cellular response to oxidative stress (25%) cell redox homeostasis (25%)" cytoplasm (25%) thioredoxin peroxidase activity (25%) "IPR000866 (20.7%) IPR013766 (20.7%) IPR050924 (20.7%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.7%) Thioredoxin domain (20.7%) Thiol-specific peroxidase BCP/PrxQ (20.7%)" DGSNPTSTDKFNHSLWPHAWYCLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.3%) IPR011990 (32.4%) IPR012944 (32.4%)" "SusD-like, N-terminal (35.3%) Tetratricopeptide-like helical domain superfamily (32.4%) RagB/SusD domain (32.4%)" VPVEQLNAGDLGCTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" TGGLELFTNLNYYGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (10%) GO:0009279 (80%) GO:0015344 (10%) siderophore transmembrane transport (10%) cell outer membrane (80%) siderophore uptake transmembrane transporter activity (10%) "IPR008969 (24.2%) IPR037066 (24.2%) IPR041700 (24.2%)" "Carboxypeptidase-like, regulatory domain superfamily (24.2%) TonB-dependent receptor, plug domain superfamily (24.2%) Outer membrane protein beta-barrel domain 3 (24.2%)" VLPDVGLLK root "GO:0046657 (11.1%) GO:0046949 (11.1%)" "GO:0005737 (11.1%) GO:0005777 (11.1%)" "GO:0004467 (11.1%) GO:0008840 (11.1%) GO:0016805 (11.1%)" "folic acid catabolic process (11.1%) fatty-acyl-CoA biosynthetic process (11.1%)" "cytoplasm (11.1%) peroxisome (11.1%)" "long-chain fatty acid-CoA ligase activity (11.1%) 4-hydroxy-tetrahydrodipicolinate synthase activity (11.1%) dipeptidase activity (11.1%)" "IPR002035 (25.6%) IPR002881 (25.6%) IPR036465 (23.3%)" "von Willebrand factor, type A (25.6%) Domain of unknown function DUF58 (25.6%) von Willebrand factor A-like domain superfamily (23.3%)" LASSNDDNVLQNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19.2%) "GO:0000155 (20.3%) GO:0003700 (20.3%) GO:0043565 (20.3%)" membrane (19.2%) "phosphorelay sensor kinase activity (20.3%) DNA-binding transcription factor activity (20.3%) sequence-specific DNA binding (20.3%)" "IPR001789 (7.8%) IPR003594 (7.8%) IPR003661 (7.8%)" "Signal transduction response regulator, receiver domain (7.8%) Histidine kinase/HSP90-like ATPase domain (7.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.8%)" VFFDNTLENLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR031965 (50%)" "Immunoglobulin-like fold (50%) Starch-binding module 26 (50%)" ADEDEGLTASPMFER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032276 (100%) Protein of unknown function DUF4836 (100%) LLFTLNPALPYTAYSDKER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) AKVNCYGADDVR Bacteria Bacteria IPR025964 (100%) GGGtGRT protein (100%) FAQNFYMNVAGQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (31.8%) GO:0009279 (36.4%) GO:0015344 (31.8%) siderophore transmembrane transport (31.8%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (31.8%) "IPR057601 (23.5%) IPR036942 (20.6%) IPR039426 (20.6%)" "TonB-dependent transporter Oar-like, beta-barrel domain (23.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.6%) TonB-dependent receptor-like (20.6%)" EGLDTLR root "1.1.2.4 (37.7%) 3.6.-.- (12.2%) 1.2.1.11 (6.7%)" "D-lactate dehydrogenase (cytochrome) (37.7%) Acting on acid anhydrides (12.2%) aspartate-semialdehyde dehydrogenase (6.7%)" "GO:1903457 (4.2%) GO:0006506 (1.3%) GO:0002098 (1.2%)" "GO:0005739 (4.3%) GO:0005737 (2.8%) GO:0005829 (2.6%)" "GO:0004458 (4.2%) GO:0008720 (4.2%) GO:0071949 (4%)" "lactate catabolic process (4.2%) GPI anchor biosynthetic process (1.3%) tRNA wobble uridine modification (1.2%)" "mitochondrion (4.3%) cytoplasm (2.8%) cytosol (2.6%)" "D-lactate dehydrogenase (cytochrome) activity (4.2%) D-lactate dehydrogenase (NAD+) activity (4.2%) FAD binding (4%)" "IPR016164 (3%) IPR027417 (3%) IPR004113 (3%)" "FAD-linked oxidase-like, C-terminal (3%) P-loop containing nucleoside triphosphate hydrolase (3%) FAD-binding oxidoreductase/transferase, type 4, C-terminal (3%)" NVEFAQLEQLAHQTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002547 (7.7%) IPR004532 (7.7%) IPR005121 (7.7%)" "tRNA-binding domain (7.7%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.7%) Ferrodoxin-fold anticodon-binding domain (7.7%)" FLDTTTDLCPNWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) GO:0005737 (25%) "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) cytoplasm (25%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR028923 (51.4%) IPR018236 (48.6%)" "SAICAR synthetase/ADE2, N-terminal (51.4%) SAICAR synthetase, conserved site (48.6%)" GLTLHADANLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" ADDFMFK root "2.4.1.- (50%) 2.7.13.3 (50%)" "Hexosyltransferases (50%) histidine kinase (50%)" "GO:0006826 (8.8%) GO:0008299 (2.9%)" "GO:0009279 (76.5%) GO:0016020 (2.9%)" "GO:0016301 (2.9%) GO:0080043 (2.9%) GO:0080044 (2.9%)" "iron ion transport (8.8%) isoprenoid biosynthetic process (2.9%)" "cell outer membrane (76.5%) membrane (2.9%)" "kinase activity (2.9%) quercetin 3-O-glucosyltransferase activity (2.9%) quercetin 7-O-glucosyltransferase activity (2.9%)" "IPR012910 (13.7%) IPR023996 (13.7%) IPR023997 (13.7%)" "TonB-dependent receptor, plug domain (13.7%) TonB-dependent outer membrane protein, SusC/RagA (13.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.7%)" HMDLNYEHLFRL Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (33.3%) IPR015854 (33.3%) IPR027417 (33.3%)" "ABC transporter-like, ATP-binding domain (33.3%) ABC transporter, lipoprotein release, LolD-like (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" SPAVDAPAAGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (22.9%) GO:0016020 (2.1%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (22.9%) membrane (2.1%)" protein-disulfide reductase activity (25%) "IPR003834 (25.3%) IPR013766 (25.3%) IPR028250 (25.3%)" "Cytochrome C biogenesis protein, transmembrane domain (25.3%) Thioredoxin domain (25.3%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.3%)" YHLTSFCAPPTLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.1 (100%) acetate--CoA ligase (100%) "GO:0006633 (16.7%) GO:0006637 (16.7%)" "GO:0004321 (16.7%) GO:0005524 (16.7%) GO:0015645 (16.7%)" "fatty acid biosynthetic process (16.7%) acyl-CoA metabolic process (16.7%)" "fatty-acyl-CoA synthase activity (16.7%) ATP binding (16.7%) fatty acid ligase activity (16.7%)" "IPR000873 (16.9%) IPR020845 (16.9%) IPR025110 (16.9%)" "AMP-dependent synthetase/ligase domain (16.9%) AMP-binding, conserved site (16.9%) AMP-binding enzyme, C-terminal domain (16.9%)" LTYKPYFTWDTDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) KNESVNSLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015159 (100%) polysaccharide transmembrane transporter activity (100%) "IPR003715 (33.3%) IPR019554 (33.3%) IPR049712 (33.3%)" "Polysaccharide export protein, N-terminal domain (33.3%) Soluble ligand binding domain (33.3%) Polysaccharide export protein (33.3%)" LTANLASLDVQGTLNK Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) "IPR003399 (50%) IPR052336 (50%)" "Mce/MlaD (50%) MlaD Inter-membrane Phospholipid Transporter (50%)" EAEHQLLYEPYTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR024213 (100%) Protein of unknown function DUF3822 (100%) QFTPGTPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (71.4%) IPR008160 (28.6%)" "Domain of unknown function DUF4988 (71.4%) Collagen triple helix repeat (28.6%)" GAGELLFTSMDHDGVK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "4.3.2.10 (91.4%) 4.1.3.- (7.4%) 5.3.1.16 (1.2%)" "imidazole glycerol-phosphate synthase (91.4%) Oxo-acid-lyases (7.4%) 1-(5-phosphoribosyl)-5[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamidisomerase (1.2%)" GO:0000105 (24.9%) GO:0005737 (24.5%) "GO:0000107 (24.9%) GO:0016829 (24.9%) GO:0003949 (0.4%)" L-histidine biosynthetic process (24.9%) cytoplasm (24.5%) "imidazoleglycerol-phosphate synthase activity (24.9%) lyase activity (24.9%) 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity (0.4%)" "IPR004651 (20%) IPR006062 (20%) IPR050064 (20%)" "Histidine biosynthesis, HisF (20%) Histidine biosynthesis protein (20%) Imidazole glycerol phosphate synthase HisA/HisF (20%)" KNDAAFFDVDWLHFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (21%) IPR006710 (20.3%) IPR051795 (20.3%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (21%) Glycoside hydrolase, family 43 (20.3%) Glycosyl Hydrolase Family 43 (20.3%)" MNNQLLLDNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.7 (100%) adenine phosphoribosyltransferase (100%) "GO:0006166 (14.3%) GO:0006168 (14.3%) GO:0044209 (14.3%)" GO:0005737 (14.3%) "GO:0002055 (14.3%) GO:0003999 (14.3%) GO:0016208 (14.3%)" "purine ribonucleoside salvage (14.3%) adenine salvage (14.3%) AMP salvage (14.3%)" cytoplasm (14.3%) "adenine binding (14.3%) adenine phosphoribosyltransferase activity (14.3%) AMP binding (14.3%)" "IPR000836 (25.4%) IPR005764 (25.4%) IPR050054 (25.4%)" "Phosphoribosyltransferase domain (25.4%) Adenine phosphoribosyl transferase (25.4%) Uracil phosphoribosyltransferase/Adenine phosphoribosyltransferase (25.4%)" TGYPVQHNLLSATVLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.1.180 (100%) FAD:protein FMN transferase (100%) GO:0016020 (25.5%) "GO:0016740 (38.2%) GO:0046872 (36.3%)" membrane (25.5%) "transferase activity (38.2%) metal ion binding (36.3%)" "IPR024932 (51.3%) IPR003374 (48.7%)" "Flavin transferase ApbE (51.3%) ApbE-like superfamily (48.7%)" VELENGVDLTAHLSGK Pseudomonadati Bacteria Pseudomonadati GO:0005829 (25%) "GO:0003743 (25%) GO:0043022 (25%) GO:0019843 (23.5%)" cytosol (25%) "translation initiation factor activity (25%) ribosome binding (25%) rRNA binding (23.5%)" "IPR003029 (25%) IPR004368 (25%) IPR006196 (25%)" "S1 domain (25%) Translation initiation factor IF-1 (25%) RNA-binding domain, S1, IF1 type (25%)" DLFNPSYENLYVNNEDVMNEVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25%) IPR004659 (25%) IPR012340 (25%)" "S1 domain (25%) Ribonuclease E/G (25%) Nucleic acid-binding, OB-fold (25%)" VTDDELGSQADGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LDGQVLDK root "3.4.11.2 (50%) 3.6.1.- (50%)" "membrane alanyl aminopeptidase (50%) In phosphorus-containing anhydrides (50%)" "GO:0007076 (2.4%) GO:0051301 (2.4%) GO:0006107 (0.8%)" "GO:0033644 (67.7%) GO:0005634 (3.2%) GO:0000796 (2.4%)" "GO:0005524 (2.4%) GO:0016887 (2.4%) GO:0000287 (0.8%)" "mitotic chromosome condensation (2.4%) cell division (2.4%) oxaloacetate metabolic process (0.8%)" "host cell membrane (67.7%) nucleus (3.2%) condensin complex (2.4%)" "ATP binding (2.4%) ATP hydrolysis activity (2.4%) magnesium ion binding (0.8%)" "IPR022747 (62.2%) IPR003395 (2.2%) IPR010935 (2.2%)" "Salmonella outer protein D (62.2%) RecF/RecN/SMC, N-terminal (2.2%) SMCs flexible hinge (2.2%)" NPEYFVDCFNAVQELLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.4%) GO:0006164 (1.1%)" GO:0005737 (20.4%) "GO:0004642 (20.4%) GO:0005524 (19.4%) GO:0046872 (19.4%)" "'de novo' IMP biosynthetic process (19.4%) purine nucleotide biosynthetic process (1.1%)" cytoplasm (20.4%) "phosphoribosylformylglycinamidine synthase activity (20.4%) ATP binding (19.4%) metal ion binding (19.4%)" "IPR010918 (11.3%) IPR036676 (11.3%) IPR036921 (11.3%)" "PurM-like, C-terminal domain (11.3%) PurM-like, C-terminal domain superfamily (11.3%) PurM-like, N-terminal domain superfamily (11.3%)" TLNVSSLAPNDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (66.7%) IPR011047 (27.8%) IPR011044 (5.6%)" "WD40/YVTN repeat-like-containing domain superfamily (66.7%) Quinoprotein alcohol dehydrogenase-like superfamily (27.8%) Quinoprotein amine dehydrogenase, beta chain-like (5.6%)" VMATFEENVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (35.7%) IPR011042 (32.1%) IPR029058 (32.1%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (35.7%) Six-bladed beta-propeller, TolB-like (32.1%) Alpha/Beta hydrolase fold (32.1%)" DHAVLYLPLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009244 (33.3%) GO:0005886 (33.3%) GO:0016776 (33.3%) lipopolysaccharide core region biosynthetic process (33.3%) plasma membrane (33.3%) phosphotransferase activity, phosphate group as acceptor (33.3%) "IPR000917 (26%) IPR040423 (26%) IPR017850 (24.7%)" "Sulfatase, N-terminal (26%) Phosphoethanolamine transferase (26%) Alkaline-phosphatase-like, core domain superfamily (24.7%)" TTFHPDSDYASFVGTYKPLTEEVDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR027417 (35.8%) IPR052934 (35.8%) IPR011704 (28.3%)" "P-loop containing nucleoside triphosphate hydrolase (35.8%) Methylated DNA Recognition and Restriction Enzymes (35.8%) ATPase, dynein-related, AAA domain (28.3%)" QQGQGQLQLPLSDCGVVALDYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.7%) GO:0006164 (0.5%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.5%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR055181 (11.4%) IPR010073 (11.1%) IPR010918 (11.1%)" "FGAR-AT, PurM N-terminal-like domain (11.4%) Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%)" AVSVLSTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (26.3%) IPR017853 (24.8%) IPR045857 (24.8%)" "Glycosyl hydrolase family 13, catalytic domain (26.3%) Glycoside hydrolase superfamily (24.8%) Oligo-1,6-glucosidase, domain 2 (24.8%)" HQFWVVSDDQDLATLTAEFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR008323 (100%) Uncharacterised conserved protein UCP033563 (100%) AAGLGALADVVVNHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (50%) "GO:0004556 (25%) GO:0043169 (25%)" carbohydrate metabolic process (50%) "alpha-amylase activity (25%) cation binding (25%)" "IPR006047 (50%) IPR006046 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (50%) Alpha amylase (25%) Glycoside hydrolase superfamily (25%)" EGDYLSLNGTTGQVYAGQLETK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (97.4%) 2.7.-.- (2.6%)" "pyruvate, phosphate dikinase (97.4%) Transferring phosphorus-containing groups (2.6%)" "GO:0050242 (25.5%) GO:0005524 (24.8%) GO:0016301 (24.8%)" "pyruvate, phosphate dikinase activity (25.5%) ATP binding (24.8%) kinase activity (24.8%)" "IPR000121 (10.2%) IPR010121 (10.2%) IPR015813 (10.2%)" "PEP-utilising enzyme, C-terminal (10.2%) Pyruvate, phosphate dikinase (10.2%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.2%)" YLDSLGNNFPYLLLRPTGVYGPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR001509 (34.5%) IPR036291 (32.7%) IPR050177 (32.7%)" "NAD-dependent epimerase/dehydratase (34.5%) NAD(P)-binding domain superfamily (32.7%) Bifunctional lipid A modification and metabolic enzymes (32.7%)" NYLSSMPGEYGDLLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.5%) IPR019533 (25.5%) IPR019758 (25.5%)" "Peptidase S26A, signal peptidase I (25.5%) Peptidase S26 (25.5%) Peptidase S26A, signal peptidase I, conserved site (25.5%)" FLCTVCGYLYEGTEAPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005506 (50%) GO:0004601 (42.3%) GO:0016491 (7.7%)" "iron ion binding (50%) peroxidase activity (42.3%) oxidoreductase activity (7.7%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" NFLVYDK root "6.2.1.45 (33.3%) 1.7.99.4 (16.7%) 3.1.-.- (16.7%)" "E1 ubiquitin-activating enzyme (33.3%) Transferred entry: 1.7.1.1, 1.7.1.2, 1.7.1.3, 1.7.5.1, 1.7.7.2 an1.9.6.1 (16.7%) Acting on ester bonds (16.7%)" "GO:0016925 (0.9%) GO:0031640 (0.9%) GO:0000209 (0.4%)" "GO:0016020 (20.6%) GO:0005576 (2.2%) GO:0005737 (0.9%)" "GO:0003700 (16.6%) GO:0043565 (16.6%) GO:0000155 (14.8%)" "protein sumoylation (0.9%) killing of cells of another organism (0.9%) protein polyubiquitination (0.4%)" "membrane (20.6%) extracellular region (2.2%) cytoplasm (0.9%)" "DNA-binding transcription factor activity (16.6%) sequence-specific DNA binding (16.6%) phosphorelay sensor kinase activity (14.8%)" "IPR011110 (9.5%) IPR015943 (9%) IPR011123 (8.6%)" "Two component regulator propeller (9.5%) WD40/YVTN repeat-like-containing domain superfamily (9%) Two component regulator three Y (8.6%)" ENVQFLATR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LNQEPFLESVRDLDDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (16%) IPR039426 (16%) IPR012910 (14.2%)" "TonB-dependent outer membrane protein, SusC/RagA (16%) TonB-dependent receptor-like (16%) TonB-dependent receptor, plug domain (14.2%)" LSYLGMVAQNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" ELVWEYYQSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (72.2%) GO:0016740 (27.8%)" "ATP binding (72.2%) transferase activity (27.8%)" "IPR002575 (26%) IPR005337 (25%) IPR053931 (25%)" "Aminoglycoside phosphotransferase (26%) RapZ-like family (25%) RapZ, C-terminal domain (25%)" QFLDVMGVGR Pseudomonadati Bacteria Pseudomonadati 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (34.1%) "GO:0004475 (34.1%) GO:0005525 (30.8%) GO:0016853 (1.1%)" GDP-mannose biosynthetic process (34.1%) "mannose-1-phosphate guanylyltransferase (GTP) activity (34.1%) GTP binding (30.8%) isomerase activity (1.1%)" "IPR005835 (25.8%) IPR051161 (25.8%) IPR029044 (25%)" "Nucleotidyl transferase domain (25.8%) Mannose-6-phosphate isomerase type 2 (25.8%) Nucleotide-diphospho-sugar transferases (25%)" DADELVQLYLR Pseudomonadati Bacteria Pseudomonadati 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (32.7%) "GO:0008422 (33.3%) GO:0016787 (0.7%)" glucan catabolic process (33.3%) periplasmic space (32.7%) "beta-glucosidase activity (33.3%) hydrolase activity (0.7%)" "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" GTLLCMLLSDAGQLACWPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21.4%) GO:0009099 (21.4%)" "GO:0004455 (21.4%) GO:0046872 (19%) GO:0016853 (16.7%)" "isoleucine biosynthetic process (21.4%) L-valine biosynthetic process (21.4%)" "ketol-acid reductoisomerase activity (21.4%) metal ion binding (19%) isomerase activity (16.7%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" ACEDFFNENANNGNPYHLVEPTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GLVCTALK root "2.7.7.6 (99.3%) 2.7.9.3 (0.7%)" "DNA-directed RNA polymerase (99.3%) selenide, water dikinase (0.7%)" "GO:0006351 (15%) GO:0030003 (1%) GO:0071578 (1%)" "GO:0000428 (15.2%) GO:0055038 (1%) GO:0016324 (0.9%)" "GO:0003677 (15%) GO:0003899 (15%) GO:0000287 (14.5%)" "DNA-templated transcription (15%) intracellular monoatomic cation homeostasis (1%) zinc ion import across plasma membrane (1%)" "DNA-directed RNA polymerase complex (15.2%) recycling endosome membrane (1%) apical plasma membrane (0.9%)" "DNA binding (15%) DNA-directed RNA polymerase activity (15%) magnesium ion binding (14.5%)" "IPR007081 (8.8%) IPR007083 (8.8%) IPR000722 (8.7%)" "RNA polymerase Rpb1, domain 5 (8.8%) RNA polymerase Rpb1, domain 4 (8.8%) RNA polymerase, alpha subunit (8.7%)" YSVMVNGVTELLMMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" EVCRLALHQLVADGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.7%) GO:0005886 (19.7%) "GO:0003723 (20.4%) GO:0016787 (20.4%) GO:0004521 (19.7%)" mRNA catabolic process (19.7%) plasma membrane (19.7%) "RNA binding (20.4%) hydrolase activity (20.4%) RNA endonuclease activity (19.7%)" "IPR003607 (12.6%) IPR004087 (12.6%) IPR004088 (12.6%)" "HD/PDEase domain (12.6%) K Homology domain (12.6%) K Homology domain, type 1 (12.6%)" DQTFDSNGVYLASSADYTNWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) ELRAPLADPELNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (51.6%) IPR035994 (48.4%)" "Nucleoside phosphorylase domain (51.6%) Nucleoside phosphorylase superfamily (48.4%)" AAPYHAGLDSATR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.6.2.4 (92.3%) 3.6.4.12 (7.7%)" "DNA 3'-5' helicase (92.3%) DNA helicase (7.7%)" "GO:0006260 (8.3%) GO:0006281 (8.3%) GO:0006310 (8.3%)" "GO:0005737 (8.3%) GO:0030894 (8.3%) GO:0043590 (8.3%)" "GO:0005524 (8.3%) GO:0009378 (8.3%) GO:0016787 (8.3%)" "DNA replication (8.3%) DNA repair (8.3%) DNA recombination (8.3%)" "cytoplasm (8.3%) replisome (8.3%) bacterial nucleoid (8.3%)" "ATP binding (8.3%) four-way junction helicase activity (8.3%) hydrolase activity (8.3%)" "IPR001650 (7.3%) IPR002121 (7.3%) IPR004589 (7.3%)" "Helicase, C-terminal domain-like (7.3%) HRDC domain (7.3%) DNA helicase, ATP-dependent, RecQ type (7.3%)" LFGLSGNEQAGGQGTPQGELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.18 (100%) phosphoglycolate phosphatase (100%) GO:0006281 (25%) GO:0005829 (25%) "GO:0008967 (25%) GO:2001070 (25%)" DNA repair (25%) cytosol (25%) "phosphoglycolate phosphatase activity (25%) starch binding (25%)" "IPR002044 (10%) IPR006439 (10%) IPR006549 (10%)" "Carbohydrate binding module family 20 (10%) HAD hydrolase, subfamily IA (10%) HAD-superfamily hydrolase,subfamily IIIA (10%)" NPPYYLWTHNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) LDSPDPENVPGELLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.7%) IPR020845 (25.7%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.7%) ANL, N-terminal domain (24.3%)" ALHDFFQPVVDELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0000272 (50%) GO:0004553 (50%) polysaccharide catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001547 (52.2%) IPR017853 (47.8%)" "Glycoside hydrolase, family 5 (52.2%) Glycoside hydrolase superfamily (47.8%)" TDVTVALCDKDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24%)" "IPR004199 (7.9%) IPR006102 (7.9%) IPR006103 (7.9%)" "Beta galactosidase small chain/ domain 5 (7.9%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.9%) Glycoside hydrolase family 2, catalytic domain (7.9%)" WTGEGTSNKYPR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (19.6%) GO:0009279 (60.7%) GO:0015344 (19.6%) siderophore transmembrane transport (19.6%) cell outer membrane (60.7%) siderophore uptake transmembrane transporter activity (19.6%) "IPR023996 (13%) IPR039426 (13%) IPR000531 (12.6%)" "TonB-dependent outer membrane protein, SusC/RagA (13%) TonB-dependent receptor-like (13%) TonB-dependent receptor-like, beta-barrel (12.6%)" NFPMDDLVLFGSER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (10.6%) GO:0009089 (10.6%) GO:0009097 (10.6%)" "GO:0046983 (11.7%) GO:0051287 (11.7%) GO:0004073 (10.6%)" "threonine biosynthetic process (10.6%) lysine biosynthetic process via diaminopimelate (10.6%) isoleucine biosynthetic process (10.6%)" "protein dimerization activity (11.7%) NAD binding (11.7%) aspartate-semialdehyde dehydrogenase activity (10.6%)" "IPR000534 (20.8%) IPR012280 (20.8%) IPR036291 (20.8%)" "Semialdehyde dehydrogenase, NAD-binding (20.8%) Semialdehyde dehydrogenase, dimerisation domain (20.8%) NAD(P)-binding domain superfamily (20.8%)" ADDSSHNLAEPFLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0046872 (48.3%) GO:0051536 (48.3%) GO:0009055 (1.7%)" "metal ion binding (48.3%) iron-sulfur cluster binding (48.3%) electron transfer activity (1.7%)" "IPR029039 (25.2%) IPR047964 (25.2%) IPR017896 (24.4%)" "Flavoprotein-like superfamily (25.2%) Polyferredoxin EFR1-like (25.2%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (24.4%)" AQAANFPFCTLEPNLGVLTVPDER Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005737 (20.2%) "GO:0005525 (20.2%) GO:0016887 (20.2%) GO:0005524 (19.8%)" cytoplasm (20.2%) "GTP binding (20.2%) ATP hydrolysis activity (20.2%) ATP binding (19.8%)" "IPR006073 (10.2%) IPR031167 (10.2%) IPR027417 (10.1%)" "GTP binding domain (10.2%) OBG-type guanine nucleotide-binding (G) domain (10.2%) P-loop containing nucleoside triphosphate hydrolase (10.1%)" FKLEYTAEDNSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.6%) GO:0005737 (16.6%) "GO:0000049 (16.6%) GO:0004829 (16.6%) GO:0005524 (16.6%)" threonyl-tRNA aminoacylation (16.6%) cytoplasm (16.6%) "tRNA binding (16.6%) threonine-tRNA ligase activity (16.6%) ATP binding (16.6%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004154 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) Anticodon-binding (7.7%)" VTDNCALGDWVVDTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR031704 (12.9%) IPR031705 (12.9%)" "Glycoside hydrolase family 36 (12.9%) Glycosyl hydrolase family 36, N-terminal (12.9%) Glycosyl hydrolase family 36, C-terminal (12.9%)" FPDCELTENAEK Pseudomonadati Bacteria Pseudomonadati IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) ECYEQLLADLTDAEQYAPDNDNSDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32%)" GQLHEVLR root "2.4.1.21 (96.9%) 1.1.1.179 (0.8%) 2.7.11.1 (0.8%)" "starch synthase (96.9%) D-xylose 1-dehydrogenase (NADP(+), D-xylono-1,5-lactone-forming) (0.8%) non-specific serine/threonine protein kinase (0.8%)" "GO:0051016 (6.3%) GO:0030036 (6%) GO:0006974 (1.9%)" "GO:0008290 (6.3%) GO:0030863 (6%) GO:0005654 (1.9%)" "GO:0016757 (36.3%) GO:0051015 (6%) GO:0009011 (2.5%)" "barbed-end actin filament capping (6.3%) actin cytoskeleton organization (6%) DNA damage response (1.9%)" "F-actin capping protein complex (6.3%) cortical cytoskeleton (6%) nucleoplasm (1.9%)" "glycosyltransferase activity (36.3%) actin filament binding (6%) alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity (2.5%)" "IPR013534 (37.1%) IPR002189 (6%) IPR037282 (5.7%)" "Starch synthase, catalytic domain (37.1%) F-actin-capping protein subunit alpha (6%) F-actin-capping protein subunit alpha/beta (5.7%)" LYFHQQLLNDKLPLSLGGGLGQSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.8%) GO:0006529 (1.3%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (23.8%) GO:0000166 (1.3%)" "L-asparagine biosynthetic process (23.8%) obsolete asparagine biosynthetic process (1.3%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (23.8%) nucleotide binding (1.3%)" "IPR004618 (33.9%) IPR006195 (33.9%) IPR045864 (32.2%)" "Aspartate--ammonia ligase (33.9%) Aminoacyl-tRNA synthetase, class II (33.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (32.2%)" YLNMLQK root "3.1.26.4 (36.4%) 3.5.1.89 (27.3%) 1.1.1.271 (5.5%)" "ribonuclease H (36.4%) N-acetylglucosaminylphosphatidylinositol deacetylase (27.3%) GDP-L-fucose synthase (5.5%)" "GO:0015074 (16.2%) GO:0006313 (16%) GO:0006355 (7.3%)" "GO:0016020 (2.8%) GO:0005737 (0.9%) GO:0005634 (0.8%)" "GO:0003677 (19%) GO:0003676 (8.1%) GO:0003824 (0.7%)" "DNA integration (16.2%) DNA transposition (16%) regulation of DNA-templated transcription (7.3%)" "membrane (2.8%) cytoplasm (0.9%) nucleus (0.8%)" "DNA binding (19%) nucleic acid binding (8.1%) catalytic activity (0.7%)" "IPR036397 (15.8%) IPR009057 (14.1%) IPR036388 (13.2%)" "Ribonuclease H superfamily (15.8%) Homedomain-like superfamily (14.1%) Winged helix-like DNA-binding domain superfamily (13.2%)" LLEDGAFLYETAAQHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (56.3%) "GO:0016787 (25%) GO:0016829 (18.8%)" carbohydrate metabolic process (56.3%) "hydrolase activity (25%) lyase activity (18.8%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" TTLLQMHNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (20%) "GO:0005524 (20%) GO:0008784 (20%) GO:0016881 (20%)" D-alanine biosynthetic process (20%) "ATP binding (20%) alanine racemase activity (20%) acid-amino acid ligase activity (20%)" "IPR000821 (10.3%) IPR001608 (10.3%) IPR011079 (10.3%)" "Alanine racemase (10.3%) Alanine racemase, N-terminal (10.3%) Alanine racemase, C-terminal (10.3%)" DTGATLSPFNAWLLLQGLETLSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.4%) IPR006235 (17.4%) IPR015421 (16.3%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.4%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.4%) Pyridoxal phosphate-dependent transferase, major domain (16.3%)" LGTGGHGHVFLGANVPFGYVQLGPTEPSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) "GO:0005975 (19.4%) GO:0006516 (19.4%)" GO:0005829 (19.4%) "GO:0000224 (19.4%) GO:0030246 (19.4%) GO:0016798 (3.2%)" "carbohydrate metabolic process (19.4%) glycoprotein catabolic process (19.4%)" cytosol (19.4%) "peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity (19.4%) carbohydrate binding (19.4%) hydrolase activity, acting on glycosyl bonds (3.2%)" "IPR005887 (16.7%) IPR008928 (16.7%) IPR012939 (16.7%)" "Glycosyl hydrolase family 92, alpha-1,2-mannosidase, putative (16.7%) Six-hairpin glycosidase superfamily (16.7%) Glycosyl hydrolase family 92 (16.7%)" LENPQLR root "2.7.7.7 (11.8%) 2.7.11.1 (10.3%) 1.13.11.4 (8.8%)" "DNA-directed DNA polymerase (11.8%) non-specific serine/threonine protein kinase (10.3%) gentisate 1,2-dioxygenase (8.8%)" "GO:0006281 (1.9%) GO:0006355 (1.8%) GO:0006559 (1.5%)" "GO:0016020 (9.9%) GO:0005634 (3.6%) GO:0005886 (2.1%)" "GO:0008270 (2.9%) GO:0005524 (2.4%) GO:0003677 (1.8%)" "DNA repair (1.9%) regulation of DNA-templated transcription (1.8%) L-phenylalanine catabolic process (1.5%)" "membrane (9.9%) nucleus (3.6%) plasma membrane (2.1%)" "zinc ion binding (2.9%) ATP binding (2.4%) DNA binding (1.8%)" "IPR036322 (4.8%) IPR046851 (4.5%) IPR001680 (4.4%)" "WD40-repeat-containing domain superfamily (4.8%) Neurobeachin, beta-propeller domain (4.5%) WD40 repeat (4.4%)" AGLPADKHLLLFVSQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR028098 (100%) Glycosyltransferase subfamily 4-like, N-terminal domain (100%) NAGPDFFNAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0016020 (100%) membrane (100%) IPR021272 (100%) Protein of unknown function DUF2851 (100%) FLNPFSDWGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) APSTFWK root "GO:0044718 (2.4%) GO:0006629 (0.8%)" "GO:0016020 (50.4%) GO:0009279 (3.2%)" "GO:0022857 (38.4%) GO:0015344 (2.4%) GO:0005524 (0.8%)" "siderophore transmembrane transport (2.4%) lipid metabolic process (0.8%)" "membrane (50.4%) cell outer membrane (3.2%)" "transmembrane transporter activity (38.4%) siderophore uptake transmembrane transporter activity (2.4%) ATP binding (0.8%)" "IPR036259 (41.3%) IPR011701 (28%) IPR020846 (5.6%)" "MFS transporter superfamily (41.3%) Major facilitator superfamily (28%) Major facilitator superfamily domain (5.6%)" DLDAVNGAFK Bacteria Bacteria "3.2.1.23 (95.7%) 5.4.3.8 (4.3%)" "beta-galactosidase (95.7%) glutamate-1-semialdehyde 2,1-aminomutase (4.3%)" "GO:0005990 (24.4%) GO:0006782 (1.1%)" "GO:0009341 (24.4%) GO:0005737 (1.1%)" "GO:0004565 (24.4%) GO:0030246 (21.1%) GO:0008483 (1.1%)" "lactose catabolic process (24.4%) protoporphyrinogen IX biosynthetic process (1.1%)" "beta-galactosidase complex (24.4%) cytoplasm (1.1%)" "beta-galactosidase activity (24.4%) carbohydrate binding (21.1%) transaminase activity (1.1%)" "IPR006103 (8.1%) IPR032312 (8.1%) IPR050347 (8.1%)" "Glycoside hydrolase family 2, catalytic domain (8.1%) Beta-galactosidase, domain 4 (8.1%) Bacterial Beta-galactosidase (8.1%)" HAMEFLNEGNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (20%) "GO:0005829 (20%) GO:0016020 (20%)" "GO:0003743 (20%) GO:0043022 (20%)" ribosome disassembly (20%) "cytosol (20%) membrane (20%)" "translation initiation factor activity (20%) ribosome binding (20%)" "IPR001288 (17%) IPR019813 (17%) IPR019814 (17%)" "Translation initiation factor 3 (17%) Translation initiation factor 3, conserved site (17%) Translation initiation factor 3, N-terminal (17%)" KNPTLLFAGNNLGEDYLFELTSFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.8%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.8%)" "IPR001672 (20.2%) IPR018189 (20.2%) IPR035476 (20.2%)" "Phosphoglucose isomerase (PGI) (20.2%) Phosphoglucose isomerase, conserved site (20.2%) Phosphoglucose isomerase, SIS domain 1 (20.2%)" VAPEHTSPEVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0003824 (33.3%) GO:0005506 (33.3%) GO:0051539 (33.3%)" "catalytic activity (33.3%) iron ion binding (33.3%) 4 iron, 4 sulfur cluster binding (33.3%)" "IPR006638 (14.4%) IPR007197 (14.4%) IPR013704 (14.4%)" "Elp3/MiaA/NifB-like, radical SAM core domain (14.4%) Radical SAM (14.4%) UPF0313, N-terminal (14.4%)" LHVEYGSEFKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR009387 (100%) Toxin HigB-2 (100%) FRVYDDGVGLR Pseudomonadati Bacteria Pseudomonadati 3.2.1.20 (100%) alpha-glucosidase (100%) "GO:0030246 (50.7%) GO:0016787 (49.3%)" "carbohydrate binding (50.7%) hydrolase activity (49.3%)" "IPR019563 (14.4%) IPR029483 (14.4%) IPR029486 (14.4%)" "Glycosyl-hydrolase 97, catalytic domain (14.4%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.4%) Glycosyl-hydrolase 97, N-terminal domain (14.4%)" VNHNVLTLHNGLTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" ELQQMVDHCLTLTDREER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025632 (100%) Protein of unknown function DUF4290 (100%) AENQNNANNYSASNLQVLEGLEAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (13.1%) GO:0006261 (11.9%)" "GO:0005694 (11.9%) GO:0005737 (11.9%)" "GO:0003677 (13.1%) GO:0005524 (13.1%) GO:0034335 (11.9%)" "DNA topological change (13.1%) DNA-templated DNA replication (11.9%)" "chromosome (11.9%) cytoplasm (11.9%)" "DNA binding (13.1%) ATP binding (13.1%) DNA negative supercoiling activity (11.9%)" "IPR001241 (8.6%) IPR003594 (8.6%) IPR000565 (7.8%)" "DNA topoisomerase, type IIA (8.6%) Histidine kinase/HSP90-like ATPase domain (8.6%) DNA topoisomerase, type IIA, subunit B (7.8%)" FLTLQFGTPAEEYLACLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.9%) GO:0019288 (18.9%)" "GO:0046429 (18.9%) GO:0051539 (18.9%) GO:0005506 (17.1%)" "terpenoid biosynthetic process (18.9%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.9%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.9%) 4 iron, 4 sulfur cluster binding (18.9%) iron ion binding (17.1%)" "IPR004588 (26.6%) IPR011005 (25%) IPR017178 (24.2%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26.6%) Dihydropteroate synthase-like superfamily (25%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.2%)" NNNLVHQLLDLALLQNGMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (24.7%) GO:0016887 (24.7%) GO:0051082 (24.7%)" "ATP binding (24.7%) ATP hydrolysis activity (24.7%) unfolded protein binding (24.7%)" "IPR001404 (20%) IPR020568 (20%) IPR020575 (20%)" "Heat shock protein Hsp90 family (20%) Ribosomal protein uS5 domain 2-type superfamily (20%) Heat shock protein Hsp90, N-terminal (20%)" LAHSGGYNDFMPGVEVGYAFFLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR036709 (50%) IPR027385 (40%) IPR011250 (10%)" "Autotransporter beta-domain superfamily (50%) Outer membrane protein, beta-barrel domain (40%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (10%)" PVALDESSVSEETK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (47.2%) GO:0003746 (52.8%) cytoplasm (47.2%) translation elongation factor activity (52.8%) "IPR014039 (20.7%) IPR036402 (20.7%) IPR001816 (19.6%)" "Translation elongation factor EFTs/EF1B, dimerisation (20.7%) Elongation factor Ts, dimerisation domain superfamily (20.7%) Translation elongation factor EFTs/EF1B (19.6%)" SDYYAEGVLNPDMSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (26%) IPR041700 (26%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (26%) Outer membrane protein beta-barrel domain 3 (26%) TonB-dependent receptor, plug domain superfamily (25%)" EAALSYHETGRPGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006108 (16.7%) "GO:0004470 (16.7%) GO:0016616 (16.7%) GO:0016746 (16.7%)" malate metabolic process (16.7%) "malic enzyme activity (16.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.7%) acyltransferase activity (16.7%)" "IPR002505 (9.1%) IPR012188 (9.1%) IPR012301 (9.1%)" "Phosphate acetyl/butaryl transferase (9.1%) NAD(P)-dependent malic enzyme (9.1%) Malic enzyme, N-terminal domain (9.1%)" SYDSGYQSLMGVPYDSWTGFNFHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TGTLTLPNQNLDFTKQEDLDLETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.3.4 (100%) Transferred entry: 7.2.2.9 (100%) "GO:0055070 (14.3%) GO:0060003 (14.3%)" GO:0005886 (14.3%) "GO:0005507 (14.3%) GO:0005524 (14.3%) GO:0016887 (14.3%)" "copper ion homeostasis (14.3%) copper ion export (14.3%)" plasma membrane (14.3%) "copper ion binding (14.3%) ATP binding (14.3%) ATP hydrolysis activity (14.3%)" "IPR001757 (12.9%) IPR006121 (12.9%) IPR018303 (12.9%)" "P-type ATPase (12.9%) Heavy metal-associated domain, HMA (12.9%) P-type ATPase, phosphorylation site (12.9%)" VDVKDEEFSSELLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) "GO:0005886 (31.4%) GO:0016020 (2%)" GO:0008324 (33.3%) potassium ion transport (33.3%) "plasma membrane (31.4%) membrane (2%)" monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.8%) IPR050144 (25.8%) IPR006512 (24.2%)" "Regulator of K+ conductance, C-terminal (25.8%) AAE Transporter (25.8%) YidE/YbjL duplication (24.2%)" WTDVLATFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006261 (50%) GO:0016740 (50%) DNA-templated DNA replication (50%) transferase activity (50%) "IPR027417 (50%) IPR050238 (50%)" "P-loop containing nucleoside triphosphate hydrolase (50%) DNA Replication and Repair Clamp Loader Complex (50%)" MAYAKPDFSGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (97.6%) 3.4.13.- (2.4%)" "Acting on peptide bonds (peptidases) (97.6%) Dipeptidases (2.4%)" GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) SKELYTLPAEFGWSDLGSWGSLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (33.7%) "GO:0004475 (33.7%) GO:0005525 (32.5%)" GDP-mannose biosynthetic process (33.7%) "mannose-1-phosphate guanylyltransferase (GTP) activity (33.7%) GTP binding (32.5%)" "IPR051161 (25.7%) IPR005835 (24.8%) IPR029044 (24.8%)" "Mannose-6-phosphate isomerase type 2 (25.7%) Nucleotidyl transferase domain (24.8%) Nucleotide-diphospho-sugar transferases (24.8%)" VLYLGQDLEDFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SWHNAHLYLQASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016020 (65.5%) "GO:0016757 (20.7%) GO:0016740 (13.8%)" membrane (65.5%) "glycosyltransferase activity (20.7%) transferase activity (13.8%)" "IPR050834 (51.3%) IPR029044 (48.7%)" "Glycosyltransferase 2 family enzymes (51.3%) Nucleotide-diphospho-sugar transferases (48.7%)" FDGDVDVATYTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009289 (100%) pilus (100%) IPR029141 (100%) Major fimbrial subunit protein, N-terminal (100%) EVFAESYLTQEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.26.11 (100%) ribonuclease Z (100%) "GO:0008270 (50%) GO:0042781 (50%)" "zinc ion binding (50%) 3'-tRNA processing endoribonuclease activity (50%)" "IPR001279 (34.6%) IPR013471 (34.6%) IPR036866 (30.8%)" "Metallo-beta-lactamase (34.6%) Ribonuclease Z/BN (34.6%) Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (30.8%)" YLAYNFQGTYDYANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" LLDGLETLQWSDSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) GO:0005829 (20%) "GO:0002161 (20%) GO:0004823 (20%) GO:0005524 (20%)" leucyl-tRNA aminoacylation (20%) cytosol (20%) "aminoacyl-tRNA deacylase activity (20%) leucine-tRNA ligase activity (20%) ATP binding (20%)" "IPR002302 (12.9%) IPR025709 (12.9%) IPR001412 (12.6%)" "Leucine-tRNA ligase (12.9%) Leucyl-tRNA synthetase, editing domain (12.9%) Aminoacyl-tRNA synthetase, class I, conserved site (12.6%)" LVEMEDSQYSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016747 (100%) acyltransferase activity, transferring groups other than amino-acyl groups (100%) "IPR000182 (34.6%) IPR050680 (34.6%) IPR016181 (30.8%)" "GNAT domain (34.6%) YpeA/RimI acetyltransferase (34.6%) Acyl-CoA N-acyltransferase (30.8%)" LNYSYLSR root 3.5.1.44 (100%) protein-glutamine glutaminase (100%) "GO:0000160 (10.6%) GO:0000731 (6.4%) GO:0006302 (6.4%)" "GO:0009279 (19.1%) GO:0005737 (2.1%) GO:0009425 (2.1%)" "GO:0003700 (12.8%) GO:0043565 (12.8%) GO:0003676 (6.4%)" "phosphorelay signal transduction system (10.6%) DNA synthesis involved in DNA repair (6.4%) double-strand break repair (6.4%)" "cell outer membrane (19.1%) cytoplasm (2.1%) bacterial-type flagellum basal body (2.1%)" "DNA-binding transcription factor activity (12.8%) sequence-specific DNA binding (12.8%) nucleic acid binding (6.4%)" "IPR008969 (8%) IPR012910 (8%) IPR023996 (8%)" "Carboxypeptidase-like, regulatory domain superfamily (8%) TonB-dependent receptor, plug domain (8%) TonB-dependent outer membrane protein, SusC/RagA (8%)" GNYDVTSLYGMDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.7%) "GO:0008239 (33.7%) GO:0008236 (32.6%)" proteolysis (33.7%) "dipeptidyl-peptidase activity (33.7%) serine-type peptidase activity (32.6%)" "IPR002469 (25.6%) IPR050278 (25.6%) IPR001375 (24.8%)" "Dipeptidylpeptidase IV, N-terminal domain (25.6%) Serine protease S9B/DPPIV (25.6%) Peptidase S9, prolyl oligopeptidase, catalytic domain (24.8%)" LWLFNASDGSLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LASFLATSNMTDLLSDPSGNRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004386 (100%) helicase activity (100%) "IPR007936 (40%) IPR024450 (40%) IPR014907 (20%)" "Virulence-associated protein E-like domain (40%) Domain of unknown function DUF3874 (40%) BT4734-like, N-terminal (20%)" FTSEDQFPQEFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" NPWAYNVNVLNPLDELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" TVDEVETMK Bacteria Bacteria 1.1.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR013118 (17.1%) IPR013131 (17.1%) IPR050988 (17.1%)" "Mannitol dehydrogenase, C-terminal (17.1%) Mannitol dehydrogenase, N-terminal (17.1%) Mannitol Dehydrogenase/Oxidoreductase (17.1%)" TAQDLFHNHAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.3%) IPR032466 (47.7%)" "Uronate isomerase (52.3%) Metal-dependent hydrolase (47.7%)" VYTQVDLTQLEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR019734 (25.4%) IPR025738 (25.4%) IPR011990 (23.9%)" "Tetratricopeptide repeat (25.4%) Aerotolerance-related protein BatD (25.4%) Tetratricopeptide-like helical domain superfamily (23.9%)" NVGKDAMTAEGTVNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009055 (100%) electron transfer activity (100%) "IPR000049 (20%) IPR012255 (20%) IPR014729 (20%)" "Electron transfer flavoprotein, beta-subunit, conserved site (20%) Electron transfer flavoprotein, beta subunit (20%) Rossmann-like alpha/beta/alpha sandwich fold (20%)" LELTYLGMNPQTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (32.9%) GO:0009279 (34.1%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.1%) siderophore uptake transmembrane transporter activity (32.9%) "IPR012910 (14.3%) IPR039426 (14.3%) IPR023996 (13.8%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent receptor-like (14.3%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" AGEYLQSVNEYAVYREEMGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.2%) IPR051802 (19.2%) IPR002890 (18.7%)" "Alpha-2-macroglobulin (19.2%) Alpha-2-macroglobulin-like (19.2%) Macroglobulin domain (18.7%)" NTDEAVESFLDLNGDGLPDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.3%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.3%) "IPR028994 (18.8%) IPR022045 (17.3%) IPR006530 (13.1%)" "Integrin alpha, N-terminal (18.8%) Insecticide toxin TcdB middle/N-terminal (17.3%) YD repeat (13.1%)" VTSAEDGEPLLGASLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (27.3%) GO:0009279 (45.5%) GO:0015344 (27.3%) siderophore transmembrane transport (27.3%) cell outer membrane (45.5%) siderophore uptake transmembrane transporter activity (27.3%) "IPR012910 (13.4%) IPR023996 (13.4%) IPR023997 (13.4%)" "TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.4%)" LYAATHDEGYDVAVGSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.-.- (80%) 2.4.2.53 (20%)" "Glycosyltransferases (80%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (20%)" GO:0009247 (32.9%) GO:0016020 (32.9%) "GO:0004582 (32.9%) GO:0099621 (1.4%)" glycolipid biosynthetic process (32.9%) membrane (32.9%) "dolichyl-phosphate beta-D-mannosyltransferase activity (32.9%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (1.4%)" "IPR001173 (33.8%) IPR039528 (33.8%) IPR029044 (32.4%)" "Glycosyltransferase 2-like (33.8%) DPM1-like (33.8%) Nucleotide-diphospho-sugar transferases (32.4%)" YLTAPSLDTKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003735 (25%) GO:0070181 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "structural constituent of ribosome (25%) small ribosomal subunit rRNA binding (25%)" "IPR001648 (40.2%) IPR036870 (40.2%) IPR018275 (19.7%)" "Small ribosomal subunit protein bS18 (40.2%) Small ribosomal subunit protein bS18 superfamily (40.2%) Small ribosomal subunit protein bS18, conserved site (19.7%)" ADEELDNLHSLYVDQWDWEAVLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (22.3%) GO:0006529 (2.7%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (22.3%) GO:0000166 (2.7%)" "L-asparagine biosynthetic process (22.3%) obsolete asparagine biosynthetic process (2.7%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (22.3%) nucleotide binding (2.7%)" "IPR004618 (34.6%) IPR006195 (33.3%) IPR045864 (32.1%)" "Aspartate--ammonia ligase (34.6%) Aminoacyl-tRNA synthetase, class II (33.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (32.1%)" MNNTWLQNNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EGWVSENNEHWSSNYNLSNTSDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) LELFNQYGSTGSNPGLNQAQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AAGGGFAGSTMMLAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0005283 (50%) plasma membrane (50%) amino acid:sodium symporter activity (50%) IPR001463 (100%) Sodium:alanine symporter (100%) LTTETDLVR root "2.3.1.31 (93.4%) 2.3.1.46 (6.6%)" "homoserine O-acetyltransferase (93.4%) homoserine O-succinyltransferase (6.6%)" "GO:0019281 (26.4%) GO:0008652 (0.3%)" GO:0005737 (26.6%) "GO:0008899 (26.7%) GO:0004414 (19.9%) GO:0016746 (0.1%)" "L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine (26.4%) amino acid biosynthetic process (0.3%)" cytoplasm (26.6%) "homoserine O-succinyltransferase activity (26.7%) homoserine O-acetyltransferase activity (19.9%) acyltransferase activity (0.1%)" "IPR033752 (33.4%) IPR005697 (33.3%) IPR029062 (33.3%)" "MetA family (33.4%) Homoserine O-succinyltransferase MetA (33.3%) Class I glutamine amidotransferase-like (33.3%)" YTPGTQEVPLLLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) MTQYKPNNLTYEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) STFQLFGALNPWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) HFVTGAMSFGALSK Bacteria Bacteria 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.5%)" "GO:0051538 (19.7%) GO:0046872 (19.3%) GO:0015930 (11.6%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.5%)" "3 iron, 4 sulfur cluster binding (19.7%) metal ion binding (19.3%) glutamate synthase activity (11.6%)" "IPR002932 (12.9%) IPR050711 (12.6%) IPR002489 (12.5%)" "Glutamate synthase domain (12.9%) Electron transfer and nitrogen metabolism enzyme (12.6%) Glutamate synthase, alpha subunit, C-terminal (12.5%)" CWMFSGFNVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.22.40 (100%) bleomycin hydrolase (100%) "GO:0006508 (19.9%) GO:0009636 (19.9%) GO:0043418 (19.9%)" GO:0005737 (19.9%) "GO:0070005 (19.9%) GO:0004197 (0.3%)" "proteolysis (19.9%) response to toxic substance (19.9%) homocysteine catabolic process (19.9%)" cytoplasm (19.9%) "cysteine-type aminopeptidase activity (19.9%) cysteine-type endopeptidase activity (0.3%)" "IPR000169 (33.7%) IPR004134 (33.7%) IPR038765 (32.6%)" "Cysteine peptidase, cysteine active site (33.7%) Peptidase C1B, bleomycin hydrolase (33.7%) Papain-like cysteine peptidase superfamily (32.6%)" EQMLDEMCSLMGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.4%) GO:0030163 (12.4%) GO:0051301 (0.5%)" GO:0005886 (12.4%) "GO:0004176 (12.4%) GO:0004222 (12.4%) GO:0005524 (12.4%)" "proteolysis (12.4%) protein catabolic process (12.4%) cell division (0.5%)" plasma membrane (12.4%) "ATP-dependent peptidase activity (12.4%) metalloendopeptidase activity (12.4%) ATP binding (12.4%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" LSEYAGTGPTEEQYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (29.5%) GO:0009279 (36.4%) GO:0015344 (34.1%) siderophore transmembrane transport (29.5%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (34.1%) "IPR036942 (50.8%) IPR039426 (49.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50.8%) TonB-dependent receptor-like (49.2%)" VWDAMLNDMYDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" VVSFNEFQLELGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (25.2%) GO:0016020 (25.2%) "GO:0004222 (25.2%) GO:0046872 (24.3%)" proteolysis (25.2%) membrane (25.2%) "metalloendopeptidase activity (25.2%) metal ion binding (24.3%)" "IPR004387 (25.2%) IPR008915 (25.2%) IPR041489 (25.2%)" "Peptidase M50, putative membrane-associated zinc metallopeptidase (25.2%) Peptidase M50 (25.2%) PDZ domain 6 (25.2%)" VYLVCGPLFLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.30.- (97.4%) 3.-.-.- (2.6%)" "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (97.4%) Hydrolases (2.6%)" "GO:0003676 (25%) GO:0004519 (25%) GO:0016787 (25%)" "nucleic acid binding (25%) endonuclease activity (25%) hydrolase activity (25%)" "IPR001604 (16.8%) IPR018524 (16.8%) IPR020821 (16.8%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (16.8%) DNA/RNA non-specific endonuclease, active site (16.8%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (16.8%)" SSMDGFSLNGLTVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) "GO:0005829 (20%) GO:0005739 (0.6%)" "GO:0004823 (20%) GO:0005524 (20%) GO:0002161 (19.4%)" leucyl-tRNA aminoacylation (20%) "cytosol (20%) mitochondrion (0.6%)" "leucine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.4%)" "IPR002300 (12.9%) IPR002302 (12.9%) IPR013155 (12.9%)" "Aminoacyl-tRNA synthetase, class Ia (12.9%) Leucine-tRNA ligase (12.9%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.9%)" EVTGDNVSQYLYHEYLLPASSLHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032533 (33.9%) IPR049208 (33.9%) IPR011004 (32.1%)" "Domain of unknown function DUF4954 (33.9%) Domain of unknown function DUF6819 (33.9%) Trimeric LpxA-like superfamily (32.1%)" VKELDYLVQFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) "IPR011579 (50%) IPR027417 (50%)" "ATPase domain (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" KLTGNVSDAMGPLLGATVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.4%) IPR012910 (14.4%) IPR023996 (14.4%)" "Carboxypeptidase-like, regulatory domain superfamily (14.4%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" SAFNTSPLSPVYSDNNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" NLYYQLQLNWAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" NRELYDPVLTFQLSNDFHVR Pseudomonadati Bacteria Pseudomonadati 3.5.-.- (100%) Acting on carbon-nitrogen bonds, other than peptide bonds (100%) "GO:0016747 (60.7%) GO:0016787 (39.3%)" "acyltransferase activity, transferring groups other than amino-acyl groups (60.7%) hydrolase activity (39.3%)" "IPR000182 (20%) IPR001110 (20%) IPR003010 (20%)" "GNAT domain (20%) Uncharacterised protein family UPF0012, conserved site (20%) Carbon-nitrogen hydrolase (20%)" AYAQSVSSADKGGVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.5%) GO:0009099 (16.5%)" GO:0005829 (16.8%) "GO:0000287 (16.5%) GO:0004160 (16.5%) GO:0051537 (16.5%)" "isoleucine biosynthetic process (16.5%) L-valine biosynthetic process (16.5%)" cytosol (16.8%) "magnesium ion binding (16.5%) dihydroxy-acid dehydratase activity (16.5%) 2 iron, 2 sulfur cluster binding (16.5%)" "IPR000581 (16.8%) IPR020558 (16.8%) IPR056740 (16.8%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.8%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.8%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (16.8%)" FLLEDLDK root "5.6.2.2 (77.2%) 2.7.13.3 (5.3%) 2.1.2.5 (3.5%)" "DNA topoisomerase (ATP-hydrolyzing) (77.2%) histidine kinase (5.3%) glutamate formimidoyltransferase (3.5%)" "GO:0006265 (7.4%) GO:0006261 (4%) GO:0006270 (2.3%)" "GO:0009279 (14.8%) GO:0005737 (8.1%) GO:0009330 (7.4%)" "GO:0003677 (8.1%) GO:0005524 (7.8%) GO:0034335 (5.8%)" "DNA topological change (7.4%) DNA-templated DNA replication (4%) DNA replication initiation (2.3%)" "cell outer membrane (14.8%) cytoplasm (8.1%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (7.4%)" "DNA binding (8.1%) ATP binding (7.8%) DNA negative supercoiling activity (5.8%)" "IPR011990 (11.4%) IPR012944 (10.7%) IPR033985 (10.7%)" "Tetratricopeptide-like helical domain superfamily (11.4%) RagB/SusD domain (10.7%) SusD-like, N-terminal (10.7%)" KVDVALPLGLSYEYMNVLLDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025665 (100%) Outer membrane protein, beta-barrel domain 2 (100%) TALVYGLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0034605 (24.4%) GO:0006508 (1.2%)" GO:0005737 (24.4%) "GO:0005524 (24.4%) GO:0016887 (24.4%) GO:0008233 (1.2%)" "cellular response to heat (24.4%) proteolysis (1.2%)" cytoplasm (24.4%) "ATP binding (24.4%) ATP hydrolysis activity (24.4%) peptidase activity (1.2%)" "IPR003959 (10.5%) IPR050130 (10.5%) IPR003593 (10.2%)" "ATPase, AAA-type, core (10.5%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (10.5%) AAA+ ATPase domain (10.2%)" TLNYLQVPLFAHLAWGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR025665 (72.4%) IPR011250 (27.6%)" "Outer membrane protein, beta-barrel domain 2 (72.4%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (27.6%)" YFFVAVLK root 3.-.-.- (100%) Hydrolases (100%) "GO:0005886 (5.7%) GO:0016020 (1%)" "GO:0003676 (21.9%) GO:0004519 (21.9%) GO:0016787 (21.9%)" "plasma membrane (5.7%) membrane (1%)" "nucleic acid binding (21.9%) endonuclease activity (21.9%) hydrolase activity (21.9%)" "IPR001604 (16%) IPR020821 (16%) IPR040255 (16%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (16%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (16%) Non-specific endonuclease (16%)" TETYALFADNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FRPFLAFR root 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) "GO:0005980 (33%) GO:0005975 (0.1%) GO:0009103 (0.1%)" GO:0005886 (0.1%) "GO:0004134 (33%) GO:0004135 (33%) GO:0016740 (0.2%)" "glycogen catabolic process (33%) carbohydrate metabolic process (0.1%) lipopolysaccharide biosynthetic process (0.1%)" plasma membrane (0.1%) "4-alpha-glucanotransferase activity (33%) amylo-alpha-1,6-glucosidase activity (33%) transferase activity (0.2%)" "IPR024742 (20.1%) IPR010401 (19.9%) IPR032790 (19.9%)" "Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.1%) Glycogen debranching enzyme (19.9%) Glycogen debranching enzyme, C-terminal (19.9%)" LMFEALDR root "3.6.4.12 (33.3%) 4.3.1.24 (33.3%) 6.1.1.21 (33.3%)" "DNA helicase (33.3%) phenylalanine ammonia-lyase (33.3%) histidine--tRNA ligase (33.3%)" "GO:0006427 (0.4%) GO:0006559 (0.4%) GO:0032543 (0.4%)" "GO:0005694 (23%) GO:0005773 (0.9%) GO:0005886 (0.9%)" "GO:0005524 (23.5%) GO:0016787 (23%) GO:0043139 (23%)" "histidyl-tRNA aminoacylation (0.4%) L-phenylalanine catabolic process (0.4%) mitochondrial translation (0.4%)" "chromosome (23%) vacuole (0.9%) plasma membrane (0.9%)" "ATP binding (23.5%) hydrolase activity (23%) 5'-3' DNA helicase activity (23%)" "IPR041677 (15.7%) IPR041679 (15.7%) IPR047187 (15.7%)" "DNA2/NAM7 helicase, helicase domain (15.7%) DNA2/NAM7 helicase-like, C-terminal (15.7%) Upf1-like, C-terminal helicase domain (15.7%)" MDEYTGLLESMER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) IPR003423 (100%) Outer membrane efflux protein (100%) QQLLMNYR Bacteria Bacteria "6.1.1.4 (98.1%) 2.7.13.3 (1.9%)" "leucine--tRNA ligase (98.1%) histidine kinase (1.9%)" "GO:0006429 (19.5%) GO:0006351 (0.4%) GO:0007234 (0.4%)" "GO:0005829 (19.5%) GO:0016020 (0.4%)" "GO:0004823 (19.5%) GO:0005524 (19.5%) GO:0002161 (19.1%)" "leucyl-tRNA aminoacylation (19.5%) DNA-templated transcription (0.4%) osmosensory signaling via phosphorelay pathway (0.4%)" "cytosol (19.5%) membrane (0.4%)" "leucine-tRNA ligase activity (19.5%) ATP binding (19.5%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR002302 (12.5%) IPR001412 (12.3%) IPR002300 (12.3%)" "Leucine-tRNA ligase (12.5%) Aminoacyl-tRNA synthetase, class I, conserved site (12.3%) Aminoacyl-tRNA synthetase, class Ia (12.3%)" LTALQSSFSVNCLALVNGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (13%) IPR050220 (13%) IPR005743 (12.7%)" "DNA topoisomerase, type IIA, domain A (13%) Type II DNA Topoisomerases (13%) DNA gyrase, subunit A (12.7%)" TNNNSTLNLQHGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (80%) GO:0015344 (20%) cell outer membrane (80%) siderophore uptake transmembrane transporter activity (20%) "IPR036942 (80%) IPR039426 (20%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (80%) TonB-dependent receptor-like (20%)" LDLVEYFFKEPEFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006298 (17%) GO:0005829 (17%) "GO:0005524 (17%) GO:0030983 (17%) GO:0140664 (17%)" mismatch repair (17%) cytosol (17%) "ATP binding (17%) mismatched DNA binding (17%) ATP-dependent DNA damage sensor activity (17%)" "IPR007696 (9%) IPR045076 (9%) IPR007695 (8.5%)" "DNA mismatch repair protein MutS, core (9%) DNA mismatch repair MutS (9%) DNA mismatch repair protein MutS-like, N-terminal (8.5%)" YSAEGLLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR033985 (33.8%) IPR012944 (32.5%)" "Tetratricopeptide-like helical domain superfamily (33.8%) SusD-like, N-terminal (33.8%) RagB/SusD domain (32.5%)" YYASNSALTTANLGVFFDPQYQGDGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR012393 (14.4%) IPR028204 (14.4%) IPR005151 (13.8%)" "Tricorn protease (14.4%) Tricorn protease C1 domain (14.4%) Tail specific protease (13.8%)" MEEYLVSAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006261 (17%) GO:0009360 (16.7%) "GO:0003887 (16.7%) GO:0005524 (16.7%) GO:0046872 (16.7%)" DNA-templated DNA replication (17%) DNA polymerase III complex (16.7%) "DNA-directed DNA polymerase activity (16.7%) ATP binding (16.7%) metal ion binding (16.7%)" "IPR050238 (12.5%) IPR003593 (12.2%) IPR012763 (12.2%)" "DNA Replication and Repair Clamp Loader Complex (12.5%) AAA+ ATPase domain (12.2%) DNA polymerase III, subunit gamma/ tau, N-terminal (12.2%)" GYELDDLVTPLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (18.3%) GO:0046912 (6.7%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (18.3%) acyltransferase activity, acyl groups converted into alkyl on transfer (6.7%)" "IPR002020 (21.1%) IPR016142 (19.7%) IPR016143 (19.7%)" "Citrate synthase (21.1%) Citrate synthase-like, large alpha subdomain (19.7%) Citrate synthase-like, small alpha subdomain (19.7%)" YNENFVASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.1 (100%) carbonic anhydrase (100%) "GO:0004089 (50%) GO:0008270 (50%)" "carbonate dehydratase activity (50%) zinc ion binding (50%)" "IPR001765 (52%) IPR036874 (48%)" "Carbonic anhydrase (52%) Carbonic anhydrase superfamily (48%)" SYRPSVYFYGLHTFSNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AFDKVELQPGETK Bacteria Bacteria 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.5%) GO:0005975 (1.5%)" GO:0008422 (50%) "glucan catabolic process (48.5%) carbohydrate metabolic process (1.5%)" beta-glucosidase activity (50%) "IPR001764 (12.9%) IPR002772 (12.9%) IPR026891 (12.9%)" "Glycoside hydrolase, family 3, N-terminal (12.9%) Glycoside hydrolase family 3 C-terminal domain (12.9%) Fibronectin type III-like domain (12.9%)" TLLVDSTVTCR root 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%) GO:0006164 (0%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.5%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%) purine nucleotide biosynthetic process (0%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.5%)" "IPR004733 (20%) IPR036921 (20%) IPR016188 (20%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, N-terminal domain superfamily (20%) PurM-like, N-terminal domain (20%)" RNDLLLFGDNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" AEALNDLGR root "GO:0000160 (5%) GO:0006355 (5%)" GO:0009279 (80%) "GO:0003677 (5%) GO:0043531 (5%)" "phosphorelay signal transduction system (5%) regulation of DNA-templated transcription (5%)" cell outer membrane (80%) "DNA binding (5%) ADP binding (5%)" "IPR011990 (26.6%) IPR012944 (25%) IPR033985 (23.4%)" "Tetratricopeptide-like helical domain superfamily (26.6%) RagB/SusD domain (25%) SusD-like, N-terminal (23.4%)" MMEESQLGLLANVGDFSQGLTYQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030246 (50%) GO:0016798 (47.9%) GO:0016787 (2.1%)" "carbohydrate binding (50%) hydrolase activity, acting on glycosyl bonds (47.9%) hydrolase activity (2.1%)" "IPR013785 (12.6%) IPR014718 (12.6%) IPR017853 (12.6%)" "Aldolase-type TIM barrel (12.6%) Glycoside hydrolase-type carbohydrate-binding (12.6%) Glycoside hydrolase superfamily (12.6%)" SWLYVVDAAHALLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0042732 (24.5%) "GO:0005737 (24.5%) GO:0016020 (0.9%)" "GO:0048040 (24.5%) GO:0070403 (24.5%) GO:0008460 (0.9%)" D-xylose metabolic process (24.5%) "cytoplasm (24.5%) membrane (0.9%)" "UDP-glucuronate decarboxylase activity (24.5%) NAD+ binding (24.5%) dTDP-glucose 4,6-dehydratase activity (0.9%)" "IPR001509 (33.3%) IPR036291 (33.3%) IPR044516 (32.1%)" "NAD-dependent epimerase/dehydratase (33.3%) NAD(P)-binding domain superfamily (33.3%) UDP-glucuronic acid decarboxylase-like (32.1%)" EYLDEHLEVCGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (11.4%) GO:0009341 (11.4%) "GO:0016985 (65.7%) GO:0004565 (11.4%)" carbohydrate metabolic process (11.4%) beta-galactosidase complex (11.4%) "mannan endo-1,4-beta-mannosidase activity (65.7%) beta-galactosidase activity (11.4%)" "IPR045053 (47.9%) IPR017853 (43.8%) IPR013529 (8.3%)" "Mannan endo-1,4-beta-mannosidase-like (47.9%) Glycoside hydrolase superfamily (43.8%) Glycoside hydrolase, family 42, N-terminal (8.3%)" GAALYDHQTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LGLLVAMDKEFAQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.2.9 (100%) adenosylhomocysteine nucleosidase (100%) "GO:0009164 (16.3%) GO:0019284 (16.3%) GO:0019509 (16.3%)" GO:0005829 (16.3%) "GO:0008782 (16.3%) GO:0008930 (16.3%) GO:0003824 (1%)" "nucleoside catabolic process (16.3%) L-methionine salvage from S-adenosylmethionine (16.3%) L-methionine salvage from methylthioadenosine (16.3%)" cytosol (16.3%) "adenosylhomocysteine nucleosidase activity (16.3%) methylthioadenosine nucleosidase activity (16.3%) catalytic activity (1%)" "IPR000845 (35.3%) IPR010049 (33.3%) IPR035994 (31.4%)" "Nucleoside phosphorylase domain (35.3%) MTA/SAH nucleosidase (33.3%) Nucleoside phosphorylase superfamily (31.4%)" MNCLFCQTGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.1.1.192 (94.4%) 2.1.1.- (5.6%)" "23S rRNA (adenine(2503)-C(2))-methyltransferase (94.4%) Methyltransferases (5.6%)" "GO:0030488 (12.4%) GO:0070475 (12.4%)" GO:0005737 (12.3%) "GO:0051539 (12.4%) GO:0046872 (12.3%) GO:0000049 (8.5%)" "tRNA methylation (12.4%) rRNA base methylation (12.4%)" cytoplasm (12.3%) "4 iron, 4 sulfur cluster binding (12.4%) metal ion binding (12.3%) tRNA binding (8.5%)" "IPR040072 (16.8%) IPR048641 (16.8%) IPR007197 (16.7%)" "Methyltransferase (Class A) (16.8%) Dual-specificity RNA methyltransferase RlmN, N-terminal domain (16.8%) Radical SAM (16.7%)" EAFADLLPEEVAWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" DFSDLLLK root "5.6.2.4 (26.7%) 2.5.1.18 (16.7%) 3.4.16.4 (6.7%)" "DNA 3'-5' helicase (26.7%) glutathione transferase (16.7%) serine-type D-Ala-D-Ala carboxypeptidase (6.7%)" "GO:0006265 (8%) GO:0000725 (1.9%) GO:0006749 (1.2%)" "GO:0005737 (10.7%) GO:0009330 (8%) GO:0005829 (2.3%)" "GO:0003677 (12.4%) GO:0005524 (10.1%) GO:0003918 (8%)" "DNA topological change (8%) recombinational repair (1.9%) glutathione metabolic process (1.2%)" "cytoplasm (10.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (8%) cytosol (2.3%)" "DNA binding (12.4%) ATP binding (10.1%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (8%)" "IPR002205 (8.6%) IPR050220 (8.6%) IPR013757 (8.5%)" "DNA topoisomerase, type IIA, domain A (8.6%) Type II DNA Topoisomerases (8.6%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (8.5%)" LMDLSTPQVMGLLNVTPDSFYSGSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (20%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (20%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (20%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (20%)" "IPR000489 (25.2%) IPR006390 (25.2%) IPR045031 (25.2%)" "Pterin-binding domain (25.2%) Dihydropteroate synthase domain (25.2%) Dihydropteroate synthase-like (25.2%)" SLDPQSSPSYTVDGLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" VSEEDVNLACRR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.3%) IPR002772 (11.3%) IPR019800 (11.3%)" "Glycoside hydrolase, family 3, N-terminal (11.3%) Glycoside hydrolase family 3 C-terminal domain (11.3%) Glycoside hydrolase, family 3, active site (11.3%)" LNYSVAELR root GO:0009279 (66.7%) GO:0120147 (33.3%) cell outer membrane (66.7%) formylglycine-generating oxidase activity (33.3%) "IPR036942 (14.3%) IPR000531 (7.1%) IPR005532 (7.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.3%) TonB-dependent receptor-like, beta-barrel (7.1%) Sulfatase-modifying factor enzyme-like domain (7.1%)" DKVYPLTVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" SLTFPGDAEMTVDDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" FHFNTHYGDPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0005737 (12.5%) GO:0070062 (12.5%) GO:1990742 (12.5%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "cytoplasm (12.5%) extracellular exosome (12.5%) microvesicle (12.5%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR006195 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Aminoacyl-tRNA synthetase, class II (11.3%)" GDYLNLENLTLGYDLPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (15.1%) IPR039426 (15.1%) IPR012910 (14.4%)" "TonB-dependent receptor-like, beta-barrel (15.1%) TonB-dependent receptor-like (15.1%) TonB-dependent receptor, plug domain (14.4%)" RLLQALQSNLYNYEQSFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021857 (100%) Protein of unknown function DUF3467 (100%) ENFRQEYLLDFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.6.2.4 (91.7%) 3.6.1.- (4.2%) 3.6.4.12 (4.2%)" "DNA 3'-5' helicase (91.7%) In phosphorus-containing anhydrides (4.2%) DNA helicase (4.2%)" "GO:0006260 (8.6%) GO:0006281 (8.6%) GO:0006310 (8.2%)" "GO:0005737 (8.2%) GO:0030894 (8.2%) GO:0043590 (8.2%)" "GO:0016787 (8.6%) GO:0043138 (8.6%) GO:0005524 (8.2%)" "DNA replication (8.6%) DNA repair (8.6%) DNA recombination (8.2%)" "cytoplasm (8.2%) replisome (8.2%) bacterial nucleoid (8.2%)" "hydrolase activity (8.6%) 3'-5' DNA helicase activity (8.6%) ATP binding (8.2%)" "IPR018982 (7.5%) IPR001650 (7.2%) IPR002121 (7.2%)" "RQC domain (7.5%) Helicase, C-terminal domain-like (7.2%) HRDC domain (7.2%)" LYVYTGHDEDK Bacteria Bacteria "3.2.1.55 (50%) 3.2.1.8 (50%)" "non-reducing end alpha-L-arabinofuranosidase (50%) endo-1,4-beta-xylanase (50%)" "GO:0045493 (18.7%) GO:0005975 (14.7%)" "GO:0030246 (33.1%) GO:0004553 (32.7%) GO:0031176 (0.4%)" "xylan catabolic process (18.7%) carbohydrate metabolic process (14.7%)" "carbohydrate binding (33.1%) hydrolase activity, hydrolyzing O-glycosyl compounds (32.7%) endo-1,4-beta-xylanase activity (0.4%)" "IPR006710 (14.3%) IPR005084 (14.1%) IPR006584 (14.1%)" "Glycoside hydrolase, family 43 (14.3%) Carbohydrate binding module family 6 (14.1%) Cellulose binding, type IV (14.1%)" DGFVLDGTPGFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (2.7%) GO:0015159 (97.3%) membrane (2.7%) polysaccharide transmembrane transporter activity (97.3%) "IPR019554 (33.6%) IPR049712 (33.6%) IPR003715 (32.7%)" "Soluble ligand binding domain (33.6%) Polysaccharide export protein (33.6%) Polysaccharide export protein, N-terminal domain (32.7%)" FLPDKALDLMDEAAAK root "GO:0034605 (18.8%) GO:0042026 (15%) GO:0006508 (4.9%)" GO:0005737 (18.8%) "GO:0005524 (18.8%) GO:0016887 (18.8%) GO:0008233 (4.9%)" "cellular response to heat (18.8%) protein refolding (15%) proteolysis (4.9%)" cytoplasm (18.8%) "ATP binding (18.8%) ATP hydrolysis activity (18.8%) peptidase activity (4.9%)" "IPR041546 (8.4%) IPR050130 (8.4%) IPR003959 (8.4%)" "ClpA/ClpB, AAA lid domain (8.4%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.4%) ATPase, AAA-type, core (8.4%)" FKDFPLDK root 6.1.1.19 (100%) arginine--tRNA ligase (100%) "GO:0006420 (24.2%) GO:0006355 (1.1%) GO:0006826 (0.5%)" "GO:0005737 (23.7%) GO:0016020 (1.1%) GO:0009279 (0.5%)" "GO:0004814 (24.2%) GO:0005524 (24.2%) GO:0016853 (0.5%)" "arginyl-tRNA aminoacylation (24.2%) regulation of DNA-templated transcription (1.1%) iron ion transport (0.5%)" "cytoplasm (23.7%) membrane (1.1%) cell outer membrane (0.5%)" "arginine-tRNA ligase activity (24.2%) ATP binding (24.2%) isomerase activity (0.5%)" "IPR001278 (11.4%) IPR035684 (11.4%) IPR001412 (11.1%)" "Arginine-tRNA ligase (11.4%) Arginyl-tRNA synthetase, catalytic core domain (11.4%) Aminoacyl-tRNA synthetase, class I, conserved site (11.1%)" ESMLEAVLHER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.7%) IPR011990 (32.7%) IPR033985 (32.7%)" "RagB/SusD domain (34.7%) Tetratricopeptide-like helical domain superfamily (32.7%) SusD-like, N-terminal (32.7%)" TLDLLTQDAQFDLCNDLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (63.6%) IPR008160 (36.4%)" "Domain of unknown function DUF4988 (63.6%) Collagen triple helix repeat (36.4%)" EGTQHAPLYFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006260 (20.8%) GO:0005829 (22.1%) "GO:0003677 (35.1%) GO:0030527 (22.1%)" DNA replication (20.8%) cytosol (22.1%) "DNA binding (35.1%) structural constituent of chromatin (22.1%)" "IPR041607 (31.8%) IPR010992 (30.6%) IPR000119 (20%)" "HU domain fused to wHTH, Ig, or Glycine-rich motif (31.8%) Integration host factor (IHF)-like DNA-binding domain superfamily (30.6%) Histone-like DNA-binding protein (20%)" QLVEYQNEPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.26.- (100%) Endoribonucleases producing 5'-phosphomonoesters (100%) GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.4%) IPR004659 (25.4%) IPR019307 (25.4%)" "S1 domain (25.4%) Ribonuclease E/G (25.4%) RNA-binding protein AU-1/Ribonuclease E/G (25.4%)" LSELDMGYVDAAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (40%) GO:0000272 (10%)" "GO:0004553 (45%) GO:0031176 (5%)" "xylan catabolic process (40%) polysaccharide catabolic process (10%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (45%) endo-1,4-beta-xylanase activity (5%)" "IPR001000 (33.3%) IPR017853 (30%) IPR044846 (30%)" "Glycoside hydrolase family 10 domain (33.3%) Glycoside hydrolase superfamily (30%) Glycoside hydrolase family 10 (30%)" GALDHNLPLLTNAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (78.2%) 6.3.4.16 (21.8%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (78.2%) carbamoyl-phosphate synthase (ammonia) (21.8%)" "GO:0006541 (14.4%) GO:0006221 (11.2%) GO:0006526 (11.2%)" GO:0005737 (14.4%) "GO:0004088 (14.4%) GO:0005524 (14.4%) GO:0046872 (14.2%)" "glutamine metabolic process (14.4%) pyrimidine nucleotide biosynthetic process (11.2%) L-arginine biosynthetic process (11.2%)" cytoplasm (14.4%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.4%) ATP binding (14.4%) metal ion binding (14.2%)" "IPR011607 (10.2%) IPR036914 (10.2%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (10.2%) Methylglyoxal synthase-like domain superfamily (10.2%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" NAPDHGRFDLPHAVLYLGYDFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR023614 (100%) Porin domain superfamily (100%) STLLSLVCADNPQSYACDLTLFDNPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.21.10 (100%) crossover junction endodeoxyribonuclease (100%) "GO:0006281 (1.6%) GO:0006310 (1.6%)" "GO:0005737 (1.6%) GO:0048476 (1.6%)" "GO:0005524 (44.4%) GO:0016887 (44.4%) GO:0000287 (1.6%)" "DNA repair (1.6%) DNA recombination (1.6%)" "cytoplasm (1.6%) Holliday junction resolvase complex (1.6%)" "ATP binding (44.4%) ATP hydrolysis activity (44.4%) magnesium ion binding (1.6%)" "IPR003439 (19.7%) IPR003593 (19.7%) IPR017871 (19.7%)" "ABC transporter-like, ATP-binding domain (19.7%) AAA+ ATPase domain (19.7%) ABC transporter-like, conserved site (19.7%)" LGTPEYLPGEEDWVYGLLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR005543 (100%) PASTA domain (100%) LSLPFANEEELEHLMNVFDQLKQE Pseudomonadati Bacteria Pseudomonadati "GO:0007059 (25.6%) GO:0045881 (25.6%)" GO:0005694 (25.6%) GO:0003677 (23.3%) "chromosome segregation (25.6%) positive regulation of sporulation resulting in formation of a cellular spore (25.6%)" chromosome (25.6%) DNA binding (23.3%) "IPR041468 (17.7%) IPR050336 (17.7%) IPR057240 (17.7%)" "ParB/Spo0J, HTH domain (17.7%) Chromosome-partitioning and nucleoid occlusion protein (17.7%) ParB, C-terminal dimerisation domain (17.7%)" QTTVNLANFLALNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005615 (50%) GO:0004867 (50%) extracellular space (50%) serine-type endopeptidase inhibitor activity (50%) "IPR000215 (17.2%) IPR023795 (17.2%) IPR023796 (17.2%)" "Serpin family (17.2%) Serpin, conserved site (17.2%) Serpin domain (17.2%)" WEAGLELGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027385 (52.2%) IPR011250 (47.8%)" "Outer membrane protein, beta-barrel domain (52.2%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (47.8%)" VANLSLLK root "2.1.1.- (33.3%) 2.1.1.348 (33.3%) 2.7.13.3 (33.3%)" "Methyltransferases (33.3%) mRNA m(6)A methyltransferase (33.3%) histidine kinase (33.3%)" "GO:0006629 (5%) GO:0140042 (5%) GO:0043041 (2%)" "GO:0005789 (5.2%) GO:0009279 (5.2%) GO:1990281 (4.2%)" "GO:0003677 (11.4%) GO:0015288 (4.2%) GO:0015562 (4.2%)" "lipid metabolic process (5%) lipid droplet formation (5%) amino acid activation for nonribosomal peptide biosynthetic process (2%)" "endoplasmic reticulum membrane (5.2%) cell outer membrane (5.2%) efflux pump complex (4.2%)" "DNA binding (11.4%) porin activity (4.2%) efflux transmembrane transporter activity (4.2%)" "IPR001387 (10.1%) IPR010982 (10.1%) IPR009617 (4.6%)" "Cro/C1-type, helix-turn-helix domain (10.1%) Lambda repressor-like, DNA-binding domain superfamily (10.1%) Seipin family (4.6%)" RNLYSTLNAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" NPNQLLAAR Bacteria Bacteria 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (12.4%) GO:0006047 (12.4%) GO:0006487 (12.4%)" "GO:0005829 (12.4%) GO:0016020 (0.6%)" "GO:0004360 (12.4%) GO:0097367 (11.8%) GO:0015288 (0.6%)" "fructose 6-phosphate metabolic process (12.4%) UDP-N-acetylglucosamine metabolic process (12.4%) protein N-linked glycosylation (12.4%)" "cytosol (12.4%) membrane (0.6%)" "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.4%) carbohydrate derivative binding (11.8%) porin activity (0.6%)" "IPR017932 (12.7%) IPR001347 (12%) IPR005855 (12%)" "Glutamine amidotransferase type 2 domain (12.7%) SIS domain (12%) Glucosamine-fructose-6-phosphate aminotransferase, isomerising (12%)" KNLDWSLTVYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" ATSNMMLTLVDDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR039426 (13.2%) IPR000531 (12.4%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent receptor-like (13.2%) TonB-dependent receptor-like, beta-barrel (12.4%)" NGEFVDLHEVELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015744 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) succinate transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) "IPR010619 (33.3%) IPR024528 (33.3%) IPR050539 (33.3%)" "Threonine/serine exporter-like, N-terminal domain (33.3%) Threonine/Serine exporter, ThrE (33.3%) ThrE Dicarboxylate/Amino Acid Exporter (33.3%)" DLTNLEAVR root "1.1.1.133 (80%) 1.1.1.271 (20%)" "dTDP-4-dehydrorhamnose reductase (80%) GDP-L-fucose synthase (20%)" "GO:0060255 (13.3%) GO:0006281 (12%) GO:0006310 (12%)" "GO:0005634 (11%) GO:0005737 (6.8%) GO:0031011 (2.6%)" "GO:0016846 (6.5%) GO:0030170 (6.5%) GO:0016740 (3.9%)" "regulation of macromolecule metabolic process (13.3%) DNA repair (12%) DNA recombination (12%)" "nucleus (11%) cytoplasm (6.8%) Ino80 complex (2.6%)" "carbon-sulfur lyase activity (6.5%) pyridoxal phosphate binding (6.5%) transferase activity (3.9%)" "IPR043129 (29.1%) IPR004000 (28.6%) IPR000277 (9.9%)" "ATPase, nucleotide binding domain (29.1%) Actin family (28.6%) Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (9.9%)" FNLDGWSK root "GO:0006508 (12.5%) GO:0016926 (12.5%) GO:0060255 (12.5%)" "GO:0016020 (25%) GO:0005634 (12.5%)" GO:0016929 (12.5%) "proteolysis (12.5%) protein desumoylation (12.5%) regulation of macromolecule metabolic process (12.5%)" "membrane (25%) nucleus (12.5%)" deSUMOylase activity (12.5%) "IPR046209 (50%) IPR015943 (38.9%) IPR010432 (5.6%)" "Domain of unknown function DUF6242, N-terminal domain (50%) WD40/YVTN repeat-like-containing domain superfamily (38.9%) RDD (5.6%)" LDANTNGNVLYALDLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (72.7%) IPR008160 (27.3%)" "Domain of unknown function DUF4988 (72.7%) Collagen triple helix repeat (27.3%)" LLLVACGTSWHAGLLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0005975 (12.7%) GO:0006002 (12.7%) GO:0006047 (12.7%)" GO:0005829 (12.7%) "GO:0004360 (12.7%) GO:0097367 (12.7%)" "carbohydrate metabolic process (12.7%) fructose 6-phosphate metabolic process (12.7%) UDP-N-acetylglucosamine metabolic process (12.7%)" cytosol (12.7%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.7%) carbohydrate derivative binding (12.7%)" "IPR001347 (12.6%) IPR005855 (12.6%) IPR017932 (12.6%)" "SIS domain (12.6%) Glucosamine-fructose-6-phosphate aminotransferase, isomerising (12.6%) Glutamine amidotransferase type 2 domain (12.6%)" VLEFDLKNGYDAPFVWTMPVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (56.7%) IPR042278 (43.3%)" "Fimbrillin-like 1 (56.7%) Fimbrillin-like 1, N-terminal (43.3%)" LEPFPTVK root GO:0030639 (30%) "GO:0016747 (30%) GO:0016829 (20%) GO:0016874 (20%)" polyketide biosynthetic process (30%) "acyltransferase activity, transferring groups other than amino-acyl groups (30%) lyase activity (20%) ligase activity (20%)" "IPR032149 (28.3%) IPR042099 (18.9%) IPR053158 (18.9%)" "Domain of unknown function DUF4988 (28.3%) ANL, N-terminal domain (18.9%) Type 1 Capsular Polysaccharide Biosynthesis Protein CapK (18.9%)" GHLYLLEAESGSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (34.1%) IPR015854 (34.1%) IPR027417 (31.7%)" "ABC transporter-like, ATP-binding domain (34.1%) ABC transporter, lipoprotein release, LolD-like (34.1%) P-loop containing nucleoside triphosphate hydrolase (31.7%)" RWSDGLHQALEAK root "7.4.2.8 (97.2%) 7.4.2.4 (2.8%)" "protein-secreting ATPase (97.2%) chloroplast protein-transporting ATPase (2.8%)" "GO:0006605 (12.2%) GO:0017038 (12.2%) GO:0065002 (10.2%)" "GO:0005829 (9.7%) GO:0031522 (9.2%) GO:0005886 (8.1%)" "GO:0005524 (12.2%) GO:0046872 (6.2%) GO:0016464 (0.8%)" "protein targeting (12.2%) protein import (12.2%) intracellular protein transmembrane transport (10.2%)" "cytosol (9.7%) cell envelope Sec protein transport complex (9.2%) plasma membrane (8.1%)" "ATP binding (12.2%) metal ion binding (6.2%) chloroplast protein-transporting ATPase activity (0.8%)" "IPR000185 (8.5%) IPR011115 (8.5%) IPR014018 (8.4%)" "Protein translocase subunit SecA (8.5%) SecA DEAD-like, N-terminal (8.5%) SecA motor DEAD (8.4%)" VSGFVGKPESAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006298 (14.4%) GO:0032300 (14.4%) "GO:0005524 (14.4%) GO:0016887 (14.4%) GO:0030983 (14.4%)" mismatch repair (14.4%) mismatch repair complex (14.4%) "ATP binding (14.4%) ATP hydrolysis activity (14.4%) mismatched DNA binding (14.4%)" "IPR002099 (8.6%) IPR013507 (8.6%) IPR014762 (8.6%)" "DNA mismatch repair protein MutL/Mlh/PMS (8.6%) DNA mismatch repair protein, S5 domain 2-like (8.6%) DNA mismatch repair, conserved site (8.6%)" HVNTYGWPTEAEALKDPYPENR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (46.7%) IPR012640 (40%) IPR013783 (13.3%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (46.7%) Membrane lipoprotein, lipid attachment site (40%) Immunoglobulin-like fold (13.3%)" MSGFTGGALNAVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (20.6%) IPR037066 (20.6%) IPR039426 (20.6%)" "Carboxypeptidase-like, regulatory domain superfamily (20.6%) TonB-dependent receptor, plug domain superfamily (20.6%) TonB-dependent receptor-like (20.6%)" GVDSNGNPYLLTDEYGHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FLLPDTLGLLNPLQCVEYMR Pseudomonadati Bacteria Pseudomonadati GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.9%) IPR002034 (14.4%) IPR013709 (14.4%)" "Pyruvate carboxyltransferase (14.9%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.4%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.4%)" DADGLQASCEDLLSSLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025874 (90%) IPR011990 (10%)" "Double zinc ribbon (90%) Tetratricopeptide-like helical domain superfamily (10%)" KLLPCEYCGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" ELTFLSSMGAALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0061504 (34.2%) "GO:0061503 (34.2%) GO:0008641 (31.5%)" cyclic threonylcarbamoyladenosine biosynthetic process (34.2%) "tRNA threonylcarbamoyladenosine dehydratase (34.2%) ubiquitin-like modifier activating enzyme activity (31.5%)" "IPR045886 (34.7%) IPR000594 (33.3%) IPR035985 (31.9%)" "ThiF/MoeB/HesA family (34.7%) THIF-type NAD/FAD binding fold (33.3%) Ubiquitin-activating enzyme-like (31.9%)" GTLLGQMYGTLSGLGWNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" EELVNDFEAPLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.3%) GO:0019288 (24.3%)" "GO:0005524 (25.7%) GO:0050515 (25.7%)" "terpenoid biosynthetic process (24.3%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.3%)" "ATP binding (25.7%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.7%)" "IPR006204 (17.1%) IPR014721 (17.1%) IPR020568 (17.1%)" "GHMP kinase N-terminal domain (17.1%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17.1%) Ribosomal protein uS5 domain 2-type superfamily (17.1%)" LGLFTGTFDPFTLGHQNLAER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.3 (100%) pantetheine-phosphate adenylyltransferase (100%) GO:0015937 (25.2%) GO:0005737 (25.2%) "GO:0004595 (25.2%) GO:0005524 (24.4%)" coenzyme A biosynthetic process (25.2%) cytoplasm (25.2%) "pantetheine-phosphate adenylyltransferase activity (25.2%) ATP binding (24.4%)" "IPR001980 (34.1%) IPR004821 (34.1%) IPR014729 (31.8%)" "Phosphopantetheine adenylyltransferase (34.1%) Cytidyltransferase-like domain (34.1%) Rossmann-like alpha/beta/alpha sandwich fold (31.8%)" SEEVGTMEGAYDYNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.4%) GO:0005975 (1.6%)" "GO:0008422 (48.4%) GO:0004553 (1.6%)" "glucan catabolic process (48.4%) carbohydrate metabolic process (1.6%)" "beta-glucosidase activity (48.4%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.6%)" "IPR002772 (13%) IPR001764 (12.6%) IPR026891 (12.6%)" "Glycoside hydrolase family 3 C-terminal domain (13%) Glycoside hydrolase, family 3, N-terminal (12.6%) Fibronectin type III-like domain (12.6%)" TLGEVEHLLTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.6.- (100%) Sulfuric ester hydrolases (100%) GO:0009244 (32.9%) GO:0005886 (32.9%) "GO:0016776 (32.9%) GO:0016787 (1.3%)" lipopolysaccharide core region biosynthetic process (32.9%) plasma membrane (32.9%) "phosphotransferase activity, phosphate group as acceptor (32.9%) hydrolase activity (1.3%)" "IPR000917 (26%) IPR040423 (26%) IPR012549 (24%)" "Sulfatase, N-terminal (26%) Phosphoethanolamine transferase (26%) Phosphoethanolamine transferase, N-terminal (24%)" VLNLFLCGVGTVGGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.3 (51.5%) 2.7.2.4 (48.5%)" "homoserine dehydrogenase (51.5%) aspartate kinase (48.5%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7%) IPR001341 (7%) IPR001342 (7%)" "Aspartate/glutamate/uridylate kinase (7%) Aspartate kinase (7%) Homoserine dehydrogenase, catalytic (7%)" AEAYAMKEDYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DFAWDLGVNFSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (6.5%) GO:0009279 (93.5%) iron ion transport (6.5%) cell outer membrane (93.5%) "IPR039426 (14.6%) IPR012910 (14.1%) IPR023996 (14.1%)" "TonB-dependent receptor-like (14.6%) TonB-dependent receptor, plug domain (14.1%) TonB-dependent outer membrane protein, SusC/RagA (14.1%)" KFSGYVEADNGNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ESDDDQSAPPFPFLCLLVSGGNSQLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (23.5%) GO:0006508 (3.9%)" GO:0005737 (21.6%) "GO:0005506 (21.6%) GO:0016747 (11.8%) GO:0061711 (11.8%)" "tRNA threonylcarbamoyladenosine modification (23.5%) proteolysis (3.9%)" cytoplasm (21.6%) "iron ion binding (21.6%) acyltransferase activity, transferring groups other than amino-acyl groups (11.8%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (11.8%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" QLYAQVLNDLTGTTLASASSLGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR005484 (33.7%) IPR057268 (33.7%) IPR004389 (32.6%)" "Large ribosomal subunit protein uL18, bacterial/plantae/animalia (33.7%) Large ribosomal subunit protein uL18 (33.7%) Large ribosomal subunit protein uL18, bacteria (32.6%)" LSVNDSNMNYKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LTGNAVDCDEQNNLVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.4%) GO:0019288 (24.4%)" "GO:0005524 (25.6%) GO:0050515 (25.6%)" "terpenoid biosynthetic process (24.4%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.4%)" "ATP binding (25.6%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.6%)" "IPR006204 (17.1%) IPR014721 (17.1%) IPR020568 (17.1%)" "GHMP kinase N-terminal domain (17.1%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17.1%) Ribosomal protein uS5 domain 2-type superfamily (17.1%)" SLEFDER root "6.3.4.13 (34.3%) 6.3.4.2 (24.3%) 3.1.3.48 (14.3%)" "phosphoribosylamine--glycine ligase (34.3%) CTP synthase (glutamine hydrolyzing) (24.3%) protein-tyrosine-phosphatase (14.3%)" "GO:0009113 (3.8%) GO:0006189 (3.6%) GO:0019856 (2.1%)" "GO:0005886 (6%) GO:0016020 (3.6%) GO:0009986 (3.5%)" "GO:0005524 (10.4%) GO:0046872 (6.1%) GO:0004637 (3.8%)" "purine nucleobase biosynthetic process (3.8%) 'de novo' IMP biosynthetic process (3.6%) pyrimidine nucleobase biosynthetic process (2.1%)" "plasma membrane (6%) membrane (3.6%) cell surface (3.5%)" "ATP binding (10.4%) metal ion binding (6.1%) phosphoribosylamine-glycine ligase activity (3.8%)" "IPR027417 (3%) IPR008042 (2.9%) IPR000115 (2.3%)" "P-loop containing nucleoside triphosphate hydrolase (3%) Retrotransposon, Pao (2.9%) Phosphoribosylglycinamide synthetase (2.3%)" WTDLTGTMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FALTLGDELPSGLLQMAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (8.1%) IPR007121 (8.1%) IPR007645 (8.1%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.1%) RNA polymerase, beta subunit, conserved site (8.1%) RNA polymerase Rpb2, domain 3 (8.1%)" TMQAVAAAGGDMTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) ELLSTDNLR root "4.2.1.7 (66.7%) 4.2.1.42 (33.3%)" "altronate dehydratase (66.7%) galactarate dehydratase (33.3%)" "GO:0044718 (21.8%) GO:0019698 (5.5%) GO:0030003 (3.6%)" "GO:0009279 (21.8%) GO:0005743 (3.6%) GO:0000127 (1.8%)" "GO:0015344 (21.8%) GO:0008789 (3.6%) GO:0043022 (3.6%)" "siderophore transmembrane transport (21.8%) D-galacturonate catabolic process (5.5%) intracellular monoatomic cation homeostasis (3.6%)" "cell outer membrane (21.8%) mitochondrial inner membrane (3.6%) transcription factor TFIIIC complex (1.8%)" "siderophore uptake transmembrane transporter activity (21.8%) altronate dehydratase activity (3.6%) ribosome binding (3.6%)" "IPR000531 (9.8%) IPR012910 (9.8%) IPR023996 (9.8%)" "TonB-dependent receptor-like, beta-barrel (9.8%) TonB-dependent receptor, plug domain (9.8%) TonB-dependent outer membrane protein, SusC/RagA (9.8%)" YLNSEHVGDVFAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) GGASLNASNDPLYVLDGLALDNNTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" HHLDALALMEGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DAAELMLTR Pseudomonadati Bacteria Pseudomonadati 3.4.13.- (100%) Dipeptidases (100%) GO:0006508 (47.1%) "GO:0005829 (1.4%) GO:0016020 (1.4%)" "GO:0070573 (47.1%) GO:0016740 (1.4%) GO:0016811 (1.4%)" proteolysis (47.1%) "cytosol (1.4%) membrane (1.4%)" "metallodipeptidase activity (47.1%) transferase activity (1.4%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (1.4%)" "IPR011697 (25.4%) IPR008257 (24.6%) IPR029062 (24.6%)" "Peptidase C26 (25.4%) Peptidase M19 (24.6%) Class I glutamine amidotransferase-like (24.6%)" EQGEVLLLR root GO:0032790 (20%) "GO:0005829 (20%) GO:0016020 (20%)" "GO:0003743 (20%) GO:0043022 (20%)" ribosome disassembly (20%) "cytosol (20%) membrane (20%)" "translation initiation factor activity (20%) ribosome binding (20%)" "IPR001288 (17.5%) IPR019815 (17.5%) IPR019814 (17.4%)" "Translation initiation factor 3 (17.5%) Translation initiation factor 3, C-terminal (17.5%) Translation initiation factor 3, N-terminal (17.4%)" LELPEFR root "2.1.1.190 (36.8%) 2.3.1.39 (17.1%) 2.7.1.17 (9.2%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (36.8%) [acyl-carrier-protein] S-malonyltransferase (17.1%) xylulokinase (9.2%)" "GO:0070475 (4.3%) GO:0032259 (2.1%) GO:0006633 (1.8%)" "GO:0005737 (4.1%) GO:0005829 (3.6%) GO:0016020 (2.9%)" "GO:0008168 (9.3%) GO:0070041 (4.3%) GO:0005524 (3.2%)" "rRNA base methylation (4.3%) methylation (2.1%) fatty acid biosynthetic process (1.8%)" "cytoplasm (4.1%) cytosol (3.6%) membrane (2.9%)" "methyltransferase activity (9.3%) rRNA (uridine-C5-)-methyltransferase activity (4.3%) ATP binding (3.2%)" "IPR029063 (8.5%) IPR010280 (2.7%) IPR030390 (2.6%)" "S-adenosyl-L-methionine-dependent methyltransferase superfamily (8.5%) (Uracil-5)-methyltransferase family (2.7%) RNA methyltransferase TrmA, active site (2.6%)" LDDKVAVGTENK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (16.7%) GO:0015891 (16.7%) GO:0055085 (16.7%)" "GO:0030288 (16.7%) GO:0098797 (16.7%)" GO:0031992 (16.7%) "protein transport (16.7%) siderophore transport (16.7%) transmembrane transport (16.7%)" "outer membrane-bounded periplasmic space (16.7%) plasma membrane protein complex (16.7%)" energy transducer activity (16.7%) "IPR003538 (25%) IPR006260 (25%) IPR037682 (25%)" "Gram-negative bacterial TonB protein (25%) TonB/TolA, C-terminal (25%) TonB, C-terminal (25%)" LVEMLRPEGMTTPLQLVFQSLEGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (26.1%) IPR017932 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (26.1%) Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%)" VLLNNMYETLDSSNGLGLAAPQLGLPLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.1.88 (100%) peptide deformylase (100%) "GO:0006412 (25%) GO:0043686 (25%)" "GO:0042586 (25%) GO:0046872 (25%)" "translation (25%) obsolete co-translational protein modification (25%)" "peptide deformylase activity (25%) metal ion binding (25%)" "IPR023635 (50%) IPR036821 (50%)" "Peptide deformylase (50%) Peptide deformylase superfamily (50%)" KNDQLLVQPQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17.9%) GO:0045259 (17.9%)" "GO:0005524 (17.9%) GO:0043531 (17.9%) GO:0046933 (17.9%)" "plasma membrane (17.9%) proton-transporting ATP synthase complex (17.9%)" "ATP binding (17.9%) ADP binding (17.9%) proton-transporting ATP synthase activity, rotational mechanism (17.9%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" TMVTAEGEGVLEYVDATTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (8.2%) IPR015712 (8.2%) IPR007121 (7.7%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.2%) DNA-directed RNA polymerase, subunit 2 (8.2%) RNA polymerase, beta subunit, conserved site (7.7%)" LDFTQEVGFQTLANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" LSNNADVGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) IPR003423 (100%) Outer membrane efflux protein (100%) ALAVLQFK root 3.1.3.11 (100%) fructose-bisphosphatase (100%) "GO:0006094 (47.9%) GO:0000272 (0.6%) GO:0000271 (0.3%)" "GO:0016020 (1.7%) GO:0000145 (0.3%)" "GO:0042132 (47.9%) GO:0030246 (0.6%) GO:0008483 (0.3%)" "gluconeogenesis (47.9%) polysaccharide catabolic process (0.6%) polysaccharide biosynthetic process (0.3%)" "membrane (1.7%) exocyst (0.3%)" "fructose 1,6-bisphosphate 1-phosphatase activity (47.9%) carbohydrate binding (0.6%) transaminase activity (0.3%)" "IPR009164 (48.7%) IPR029052 (48.2%) IPR002102 (0.6%)" "Fructose-1,6-bisphosphatase class 3 (48.7%) Metallo-dependent phosphatase-like (48.2%) Cellulosome anchoring protein, cohesin domain (0.6%)" YLGGLWLQMLGDVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (17.4%) IPR004634 (17.4%) IPR004635 (17.4%)" "Peptidase S49 (17.4%) Peptidase S49, protease IV (17.4%) Peptidase S49, SppA (17.4%)" LAPVLLEMGCFSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (21.8%) IPR003379 (21.8%) IPR055268 (21.8%)" "Pyruvate carboxyltransferase (21.8%) Carboxylase, conserved domain (21.8%) Pyruvate carboxylase-like (21.8%)" LFFFANYENSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" LMGYEVSLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005886 (25%) "GO:0046914 (25.1%) GO:0005525 (25%) GO:0015093 (25%)" plasma membrane (25%) "transition metal ion binding (25.1%) GTP binding (25%) ferrous iron transmembrane transporter activity (25%)" "IPR007167 (9.2%) IPR003373 (9.1%) IPR011640 (9.1%)" "Ferrous iron transporter FeoA-like domain (9.2%) Ferrous iron transport protein B (9.1%) Ferrous iron transport protein B, C-terminal (9.1%)" TLQQLHAAGMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.3.1 (100%) ribulose-phosphate 3-epimerase (100%) "GO:0006098 (24.8%) GO:0019323 (24.8%)" GO:0005737 (0.8%) "GO:0004750 (24.8%) GO:0046872 (24.8%)" "pentose-phosphate shunt (24.8%) pentose catabolic process (24.8%)" cytoplasm (0.8%) "D-ribulose-phosphate 3-epimerase activity (24.8%) metal ion binding (24.8%)" "IPR000056 (25.4%) IPR026019 (25.4%) IPR011060 (24.6%)" "Ribulose-phosphate 3-epimerase-like (25.4%) Ribulose-phosphate 3-epimerase (25.4%) Ribulose-phosphate binding barrel (24.6%)" FHVENVEELLATR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006281 (20%) GO:0006310 (20%) GO:0009432 (20%)" GO:0043590 (20%) GO:0005524 (20%) "DNA repair (20%) DNA recombination (20%) SOS response (20%)" bacterial nucleoid (20%) ATP binding (20%) "IPR003395 (34.1%) IPR004604 (34.1%) IPR027417 (31.8%)" "RecF/RecN/SMC, N-terminal (34.1%) DNA recombination/repair protein RecN (34.1%) P-loop containing nucleoside triphosphate hydrolase (31.8%)" LKMEGTPTLAEWLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (24.1%) GO:0005737 (24.1%) "GO:0046872 (25.9%) GO:0070006 (24.1%) GO:0016787 (1.7%)" proteolysis (24.1%) cytoplasm (24.1%) "metal ion binding (25.9%) metalloaminopeptidase activity (24.1%) hydrolase activity (1.7%)" "IPR000587 (13.2%) IPR050422 (13.2%) IPR029149 (12.7%)" "Creatinase, N-terminal (13.2%) Xaa-Pro aminopeptidase P (13.2%) Creatinase/Aminopeptidase P/Spt16, N-terminal (12.7%)" FNEVLNGLPDWVYEEEFSFNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.-.- (50%) 3.4.14.5 (50%)" "Acting on peptide bonds (peptidases) (50%) dipeptidyl-peptidase IV (50%)" GO:0006508 (34%) "GO:0008239 (34%) GO:0008236 (32%)" proteolysis (34%) "dipeptidyl-peptidase activity (34%) serine-type peptidase activity (32%)" "IPR002469 (26%) IPR050278 (26%) IPR001375 (24.4%)" "Dipeptidylpeptidase IV, N-terminal domain (26%) Serine protease S9B/DPPIV (26%) Peptidase S9, prolyl oligopeptidase, catalytic domain (24.4%)" LGGKPGHEYMFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (25.5%) IPR017932 (25.5%) IPR029055 (24.5%)" "Phosphoribosyltransferase domain (25.5%) Glutamine amidotransferase type 2 domain (25.5%) Nucleophile aminohydrolases, N-terminal (24.5%)" SVLQDSCHQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR001623 (20.5%) IPR007791 (20.5%) IPR050817 (20.5%)" "DnaJ domain (20.5%) Co-chaperone DjlA, N-terminal (20.5%) DjlA DnaK co-chaperone (20.5%)" TGFAPSLSLSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) "IPR003423 (50%) IPR050737 (50%)" "Outer membrane efflux protein (50%) Unknown (50%)" ADASDEATQLTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR046111 (100%) Protein of unknown function DUF6048 (100%) LLETTFAGATAGAVYEGDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0008324 (33.3%) GO:0042910 (33.3%)" plasma membrane (33.3%) "monoatomic cation transmembrane transporter activity (33.3%) xenobiotic transmembrane transporter activity (33.3%)" "IPR001036 (34.4%) IPR004763 (34.4%) IPR027463 (31.1%)" "Acriflavin resistance protein (34.4%) Cation efflux system CusA-like (34.4%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.1%)" KLSTYLTK root 3.1.2.2 (100%) palmitoyl-CoA hydrolase (100%) "GO:0000278 (0.2%) GO:0007020 (0.2%) GO:0016117 (0.2%)" "GO:0005737 (2.6%) GO:0016020 (0.3%) GO:0000922 (0.2%)" "GO:0005524 (22.7%) GO:0016887 (22.6%) GO:0051082 (22.6%)" "mitotic cell cycle (0.2%) microtubule nucleation (0.2%) carotenoid biosynthetic process (0.2%)" "cytoplasm (2.6%) membrane (0.3%) spindle pole (0.2%)" "ATP binding (22.7%) ATP hydrolysis activity (22.6%) unfolded protein binding (22.6%)" "IPR001404 (17.2%) IPR020568 (17.1%) IPR020575 (17%)" "Heat shock protein Hsp90 family (17.2%) Ribosomal protein uS5 domain 2-type superfamily (17.1%) Heat shock protein Hsp90, N-terminal (17%)" LLLNSTGR root "2.5.1.6 (40%) 1.10.3.- (20%) 3.1.21.3 (20%)" "methionine adenosyltransferase (40%) With oxygen as acceptor (20%) type I site-specific deoxyribonuclease (20%)" "GO:0019646 (9.7%) GO:0007156 (2.2%) GO:0007605 (2.2%)" "GO:0005886 (12.4%) GO:0070069 (9.7%) GO:0032420 (2.2%)" "GO:0046872 (11.2%) GO:0009055 (9.9%) GO:0016682 (9.7%)" "aerobic electron transport chain (9.7%) homophilic cell-cell adhesion (2.2%) sensory perception of sound (2.2%)" "plasma membrane (12.4%) cytochrome complex (9.7%) stereocilium (2.2%)" "metal ion binding (11.2%) electron transfer activity (9.9%) oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (9.7%)" "IPR003317 (18.6%) IPR002126 (4.1%) IPR015919 (4.1%)" "Cytochrome ubiquinol oxidase subunit 2 (18.6%) Cadherin-like (4.1%) Cadherin-like superfamily (4.1%)" MNFPFFLAR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (34.8%) IPR051447 (34.8%) IPR025857 (30.3%)" "ABC3 transporter permease, C-terminal (34.8%) Lipoprotein-releasing system transmembrane protein (34.8%) MacB-like periplasmic core domain (30.3%)" ALVHEMMNAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (18.9%) GO:0019288 (18.9%)" "GO:0046429 (18.9%) GO:0051539 (18.9%) GO:0005506 (17.5%)" "terpenoid biosynthetic process (18.9%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (18.9%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (18.9%) 4 iron, 4 sulfur cluster binding (18.9%) iron ion binding (17.5%)" "IPR004588 (26.2%) IPR011005 (25%) IPR017178 (24.4%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26.2%) Dihydropteroate synthase-like superfamily (25%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.4%)" GMEETSLMDGFTETGSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" EAGGLEVPEGAEGNYYRPQQGVAHGQVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (50%) GO:0016788 (46%) GO:0016787 (4%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (46%) hydrolase activity (4%)" "IPR000801 (17.4%) IPR005181 (17.4%) IPR050583 (17.4%)" "Esterase-like (17.4%) Sialate O-acetylesterase domain (17.4%) Mycobacterial A85 antigen (17.4%)" MAVCLSQLYNENKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR048441 (50%) IPR048496 (50%)" "DUF1846, C-terminal (50%) DUF1846, N-terminal domain (50%)" NTSAENVQLQVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015920 (50%) GO:0043190 (50%) lipopolysaccharide transport (50%) ATP-binding cassette (ABC) transporter complex (50%) IPR005495 (100%) Permease LptG/LptF-related (100%) SNYDDHYKDYSAGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.7%) IPR008969 (16.7%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (16.7%) Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%)" NYDNSEFGVQELADALGLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.4%) "GO:0000155 (25.2%) GO:0003700 (25.2%) GO:0043565 (25.2%)" membrane (24.4%) "phosphorelay sensor kinase activity (25.2%) DNA-binding transcription factor activity (25.2%) sequence-specific DNA binding (25.2%)" "IPR011110 (12.7%) IPR011123 (12.7%) IPR018060 (12.7%)" "Two component regulator propeller (12.7%) Two component regulator three Y (12.7%) AraC-like, DNA binding HTH domain (12.7%)" SHVNMTDGELAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.8%) GO:0006730 (16.8%)" GO:0005737 (15.8%) "GO:0004478 (16.8%) GO:0005524 (16.8%) GO:0000287 (15.8%)" "S-adenosylmethionine biosynthetic process (16.8%) one-carbon metabolic process (16.8%)" cytoplasm (15.8%) "methionine adenosyltransferase activity (16.8%) ATP binding (16.8%) magnesium ion binding (15.8%)" "IPR002133 (17.4%) IPR022630 (17.4%) IPR022628 (16.3%)" "S-adenosylmethionine synthetase (17.4%) S-adenosylmethionine synthetase, C-terminal (17.4%) S-adenosylmethionine synthetase, N-terminal (16.3%)" TWPTGLTTCPSLLQFQLGSNDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (70%) GO:0005737 (10%) GO:0005886 (10%)" "extracellular space (70%) cytoplasm (10%) plasma membrane (10%)" "IPR001611 (16.7%) IPR027899 (16%) IPR041403 (16%)" "Leucine-rich repeat (16.7%) Domain of unknown function DUF4458 (16%) DUF4458 domain-containing protein, leucine-rich repeat (16%)" DGSSYFAK root GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (11.8%) IPR012910 (11.8%) IPR023996 (11.8%)" "Carboxypeptidase-like, regulatory domain superfamily (11.8%) TonB-dependent receptor, plug domain (11.8%) TonB-dependent outer membrane protein, SusC/RagA (11.8%)" MNFLTNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006108 (33.3%) "GO:0016615 (33.3%) GO:0016616 (33.3%)" malate metabolic process (33.3%) "malate dehydrogenase activity (33.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (33.3%)" "IPR001236 (16.7%) IPR001557 (16.7%) IPR010945 (16.7%)" "Lactate/malate dehydrogenase, N-terminal (16.7%) L-lactate/malate dehydrogenase (16.7%) Malate dehydrogenase, type 2 (16.7%)" LLYNMLDEQAWTQYLNLDDPVLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (16.8%) GO:0007165 (16.8%)" "GO:0030288 (16.8%) GO:0016020 (16.2%)" "GO:0004175 (16.8%) GO:0008236 (16.8%)" "proteolysis (16.8%) signal transduction (16.8%)" "outer membrane-bounded periplasmic space (16.8%) membrane (16.2%)" "endopeptidase activity (16.8%) serine-type peptidase activity (16.8%)" "IPR001478 (20.5%) IPR004447 (20.5%) IPR005151 (20.5%)" "PDZ domain (20.5%) C-terminal-processing peptidase S41A (20.5%) Tail specific protease (20.5%)" VSTANLTLK Bacteria Bacteria GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR000322 (14.3%) IPR011013 (14.3%) IPR013780 (14.3%)" "Glycoside hydrolase family 31, TIM barrel domain (14.3%) Galactose mutarotase-like domain superfamily (14.3%) Glycosyl hydrolase, all-beta (14.3%)" YAYVLPNDTLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006526 (14.3%) GO:0051259 (14.3%) GO:1900079 (14.3%)" GO:0005737 (14.3%) "GO:0003677 (14.3%) GO:0003700 (14.3%) GO:0034618 (14.3%)" "L-arginine biosynthetic process (14.3%) protein complex oligomerization (14.3%) regulation of arginine biosynthetic process (14.3%)" cytoplasm (14.3%) "DNA binding (14.3%) DNA-binding transcription factor activity (14.3%) arginine binding (14.3%)" "IPR001669 (16.7%) IPR020899 (16.7%) IPR020900 (16.7%)" "Arginine repressor (16.7%) Arginine repressor, C-terminal (16.7%) Arginine repressor, DNA-binding domain (16.7%)" LYEALLLPTEEASR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (52.5%) IPR042278 (47.5%)" "Fimbrillin-like 1 (52.5%) Fimbrillin-like 1, N-terminal (47.5%)" TGELEHWNTATAVNPLSSNFLNSLFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (24.1%) "GO:0000155 (25%) GO:0003700 (25%) GO:0043565 (25%)" membrane (24.1%) "phosphorelay sensor kinase activity (25%) DNA-binding transcription factor activity (25%) sequence-specific DNA binding (25%)" "IPR011110 (12.9%) IPR011123 (12.5%) IPR018060 (12.5%)" "Two component regulator propeller (12.9%) Two component regulator three Y (12.5%) AraC-like, DNA binding HTH domain (12.5%)" ATNFSKTAEDALNTLR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" NNLVDELSASYYSFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae SWSPENTSSNLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTVEAQQGDQNSLLSYTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (26.6%) IPR017853 (25%) IPR045857 (25%)" "Glycosyl hydrolase family 13, catalytic domain (26.6%) Glycoside hydrolase superfamily (25%) Oligo-1,6-glucosidase, domain 2 (25%)" VGDEVEAVLLTLDR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006412 (24.7%) GO:0008033 (0.1%)" "GO:0022627 (24.6%) GO:1990904 (0.3%) GO:0005737 (0.1%)" "GO:0003729 (24.9%) GO:0003735 (24.9%) GO:0004654 (0.1%)" "translation (24.7%) tRNA processing (0.1%)" "cytosolic small ribosomal subunit (24.6%) ribonucleoprotein complex (0.3%) cytoplasm (0.1%)" "mRNA binding (24.9%) structural constituent of ribosome (24.9%) polyribonucleotide nucleotidyltransferase activity (0.1%)" "IPR003029 (23.2%) IPR050437 (23.2%) IPR012340 (23.1%)" "S1 domain (23.2%) Small ribosomal subunit protein bS1-like (23.2%) Nucleic acid-binding, OB-fold (23.1%)" YLSLLTDFGFK Bacteria Bacteria GO:0071973 (25%) "GO:0009288 (25%) GO:0016020 (25%)" GO:0003774 (25%) bacterial-type flagellum-dependent cell motility (25%) "bacterial-type flagellum (25%) membrane (25%)" cytoskeletal motor activity (25%) "IPR010106 (97.6%) IPR025587 (1.8%) IPR000563 (0.6%)" "Recombination-promoting nuclease RpnA (97.6%) Domain of unknown function DUF4351 (1.8%) Flagellar assembly protein FliH (0.6%)" GGVYTHLATLDPATSELTLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008160 (50%) IPR032149 (50%)" "Collagen triple helix repeat (50%) Domain of unknown function DUF4988 (50%)" PLGQDLNADNEQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20%) GO:0033499 (20%)" GO:0005737 (20%) "GO:0004034 (20%) GO:0030246 (20%)" "glucose metabolic process (20%) galactose catabolic process via UDP-galactose, Leloir pathway (20%)" cytoplasm (20%) "aldose 1-epimerase activity (20%) carbohydrate binding (20%)" "IPR008183 (20%) IPR011013 (20%) IPR014718 (20%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (20%) Galactose mutarotase-like domain superfamily (20%) Glycoside hydrolase-type carbohydrate-binding (20%)" DGETVTLK root "1.1.1.3 (47.8%) 1.6.5.9 (21.7%) 2.5.1.19 (8.7%)" "homoserine dehydrogenase (47.8%) NADH:ubiquinone reductase (non-electrogenic) (21.7%) 3-phosphoshikimate 1-carboxyvinyltransferase (8.7%)" "GO:0007169 (5.7%) GO:0009086 (3.6%) GO:0009088 (3.6%)" "GO:0005886 (6.8%) GO:0043235 (5.7%) GO:0016020 (2.9%)" "GO:0005524 (8.2%) GO:0046872 (7.5%) GO:0004714 (5.7%)" "cell surface receptor protein tyrosine kinase signaling pathway (5.7%) methionine biosynthetic process (3.6%) threonine biosynthetic process (3.6%)" "plasma membrane (6.8%) receptor complex (5.7%) membrane (2.9%)" "ATP binding (8.2%) metal ion binding (7.5%) transmembrane receptor protein tyrosine kinase activity (5.7%)" "IPR013783 (7.8%) IPR003599 (4.4%) IPR007110 (4.4%)" "Immunoglobulin-like fold (7.8%) Immunoglobulin domain subtype (4.4%) Immunoglobulin-like domain (4.4%)" MVLSGEGADEVFGGYLYFHK root 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) "GO:0006529 (25.1%) GO:0006950 (0%) GO:0070981 (0%)" GO:0005829 (24.8%) "GO:0004066 (25.1%) GO:0005524 (24.6%) GO:0016874 (0.2%)" "obsolete asparagine biosynthetic process (25.1%) response to stress (0%) L-asparagine biosynthetic process (0%)" cytosol (24.8%) "asparagine synthase (glutamine-hydrolyzing) activity (25.1%) ATP binding (24.6%) ligase activity (0.2%)" "IPR001962 (14.5%) IPR050795 (14.5%) IPR014729 (14.4%)" "Asparagine synthase (14.5%) Asparagine Synthetase (14.5%) Rossmann-like alpha/beta/alpha sandwich fold (14.4%)" AEALANNPSTDFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (23.5%) GO:0009279 (76.5%) iron ion transport (23.5%) cell outer membrane (76.5%) "IPR012910 (12.4%) IPR023996 (12.4%) IPR023997 (12.4%)" "TonB-dependent receptor, plug domain (12.4%) TonB-dependent outer membrane protein, SusC/RagA (12.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.4%)" VFDFLTPYPDFDLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.2.1.22 (52.2%) 3.2.1.3 (26.1%) 3.2.1.- (21.7%)" "alpha-galactosidase (52.2%) glucan 1,4-alpha-glucosidase (26.1%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (21.7%)" "GO:0030246 (57.3%) GO:0016787 (37.1%) GO:0004557 (3.4%)" "carbohydrate binding (57.3%) hydrolase activity (37.1%) alpha-galactosidase activity (3.4%)" "IPR019563 (14.4%) IPR029486 (14.4%) IPR052720 (14.4%)" "Glycosyl-hydrolase 97, catalytic domain (14.4%) Glycosyl-hydrolase 97, N-terminal domain (14.4%) Glycosyl Hydrolase Family 97 (14.4%)" NDNHPMSEEVWGTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.2%) GO:0005829 (17.2%) "GO:0004612 (17.2%) GO:0005524 (17.2%) GO:0046872 (17.2%)" gluconeogenesis (17.2%) cytosol (17.2%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.2%) ATP binding (17.2%) metal ion binding (17.2%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" EMSLDDVVTYLATAVANR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.5%) GO:0006002 (13%)" GO:0005829 (14.5%) "GO:0003872 (14.5%) GO:0005524 (14.5%) GO:0046872 (14.5%)" "response to glucose (14.5%) fructose 6-phosphate metabolic process (13%)" cytosol (14.5%) "6-phosphofructokinase activity (14.5%) ATP binding (14.5%) metal ion binding (14.5%)" "IPR000023 (26.4%) IPR011183 (26.4%) IPR022953 (23.6%)" "Phosphofructokinase domain (26.4%) Pyrophosphate-dependent phosphofructokinase PfpB (26.4%) ATP-dependent 6-phosphofructokinase (23.6%)" KLFEEVYESDYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20%) GO:0006102 (20%)" "GO:0000287 (20%) GO:0004450 (20%) GO:0051287 (20%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "magnesium ion binding (20%) isocitrate dehydrogenase (NADP+) activity (20%) NAD binding (20%)" "IPR004790 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" VPFLDKEFLDVAMGMNPVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.3%) IPR006426 (14.3%) IPR014729 (14.3%)" "Asparagine synthase (14.3%) Asparagine synthase, glutamine-hydrolyzing (14.3%) Rossmann-like alpha/beta/alpha sandwich fold (14.3%)" MNTQLGYLPVTFADLTDDESFWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016747 (100%) acyltransferase activity, transferring groups other than amino-acyl groups (100%) "IPR000182 (50%) IPR016181 (50%)" "GNAT domain (50%) Acyl-CoA N-acyltransferase (50%)" HHFDDKEVLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.6%) GO:0051301 (12.6%) GO:0009252 (12.4%)" GO:0005737 (12.6%) "GO:0005524 (12.6%) GO:0000287 (12.2%) GO:0008765 (12.2%)" "regulation of cell shape (12.6%) cell division (12.6%) peptidoglycan biosynthetic process (12.4%)" cytoplasm (12.6%) "ATP binding (12.6%) magnesium ion binding (12.2%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.2%)" "IPR004101 (14.3%) IPR005761 (14.3%) IPR013221 (14.3%)" "Mur ligase, C-terminal (14.3%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase (14.3%) Mur ligase, central (14.3%)" SQDAGLTWK Pseudomonadati Bacteria Pseudomonadati GO:0016787 (100%) hydrolase activity (100%) "IPR046209 (55.6%) IPR015943 (44.4%)" "Domain of unknown function DUF6242, N-terminal domain (55.6%) WD40/YVTN repeat-like-containing domain superfamily (44.4%)" VFNMLVLGGLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.2.7.1 (62.5%) 1.2.7.7 (25%) 1.2.7.3 (12.5%)" "pyruvate synthase (62.5%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (25%) 2-oxoglutarate synthase (12.5%)" "GO:0016903 (89.3%) GO:0019164 (4.8%) GO:0016625 (2.4%)" "oxidoreductase activity, acting on the aldehyde or oxo group of donors (89.3%) pyruvate synthase activity (4.8%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (2.4%)" "IPR019752 (32.9%) IPR052554 (32.9%) IPR002869 (32.5%)" "Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (32.9%) 2-oxoglutarate synthase subunit KorC (32.9%) Pyruvate-flavodoxin oxidoreductase, central domain (32.5%)" CGHKPYLLVGGATGMLGDPSGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.7%) GO:0005829 (16.7%) "GO:0003723 (16.7%) GO:0004831 (16.7%) GO:0005524 (16.7%)" tyrosyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "RNA binding (16.7%) tyrosine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (12.6%) IPR002305 (12.6%) IPR002307 (12.6%)" "Aminoacyl-tRNA synthetase, class I, conserved site (12.6%) Aminoacyl-tRNA synthetase, class Ic (12.6%) Tyrosine-tRNA ligase (12.6%)" STAAEGEPNDPGFASQWHYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016485 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) protein processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000209 (16.7%) IPR015500 (16.7%) IPR022398 (16.7%)" "Peptidase S8/S53 domain (16.7%) Peptidase S8, subtilisin-related (16.7%) Peptidase S8, subtilisin, His-active site (16.7%)" LLDLLNMVEGLTLHEPERK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (50%) GO:0016491 (50%) cytosol (50%) oxidoreductase activity (50%) IPR004017 (100%) Cysteine-rich domain (100%)