peptide lca domain realm kingdom subkingdom superphylum phylum subphylum superclass class subclass superorder order suborder infraorder superfamily family subfamily tribe subtribe genus subgenus species group species subgroup species subspecies strain varietas forma EC EC - names GO (biological process) GO (cellular component) GO (molecular function) GO (biological process) - names GO (cellular component) - names GO (molecular function) - names InterPro InterPro - names TNQNMTLDLRPLCNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR015712 (8.3%) IPR007120 (8.1%) IPR007645 (8.1%)" "DNA-directed RNA polymerase, subunit 2 (8.3%) DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.1%) RNA polymerase Rpb2, domain 3 (8.1%)" SAELQFTDGVMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006271 (17.1%) "GO:0009360 (17.1%) GO:0005737 (14.6%)" "GO:0003677 (17.1%) GO:0003887 (17.1%) GO:0008408 (17.1%)" DNA strand elongation involved in DNA replication (17.1%) "DNA polymerase III complex (17.1%) cytoplasm (14.6%)" "DNA binding (17.1%) DNA-directed DNA polymerase activity (17.1%) 3'-5' exonuclease activity (17.1%)" "IPR001001 (20.6%) IPR022634 (20.6%) IPR022635 (20.6%)" "DNA polymerase III, beta sliding clamp (20.6%) DNA polymerase III, beta sliding clamp, N-terminal (20.6%) DNA polymerase III, beta sliding clamp, C-terminal (20.6%)" KGDLTSSLSALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YDATFMK root "3.5.4.33 (60%) 2.7.13.3 (20%) 5.2.1.8 (20%)" "tRNA(adenine(34)) deaminase (60%) histidine kinase (20%) peptidylprolyl isomerase (20%)" "GO:0006869 (5.9%) GO:0009636 (3.2%) GO:0002100 (2.7%)" "GO:0009279 (22.2%) GO:0016020 (7%) GO:0005783 (5.9%)" "GO:0032934 (5.9%) GO:0015562 (3.2%) GO:0042910 (3.2%)" "lipid transport (5.9%) response to toxic substance (3.2%) tRNA wobble adenosine to inosine editing (2.7%)" "cell outer membrane (22.2%) membrane (7%) endoplasmic reticulum (5.9%)" "sterol binding (5.9%) efflux transmembrane transporter activity (3.2%) xenobiotic transmembrane transporter activity (3.2%)" "IPR012944 (15.4%) IPR033985 (15.4%) IPR011990 (15%)" "RagB/SusD domain (15.4%) SusD-like, N-terminal (15.4%) Tetratricopeptide-like helical domain superfamily (15%)" VPLVLSSAEQLHSSLFQGQTDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" MNLDKDGYLNVSLENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (32.7%) IPR008978 (32.7%) IPR031107 (32.7%)" "Alpha crystallin/Hsp20 domain (32.7%) HSP20-like chaperone (32.7%) Small heat shock protein (32.7%)" YTQSNSVCYVK root "2.1.2.3 (94.2%) 3.5.4.10 (5.8%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (94.2%) IMP cyclohydrolase (5.8%)" "GO:0006189 (24.9%) GO:0006177 (0%) GO:0044208 (0%)" "GO:0005829 (24.9%) GO:0005840 (0%) GO:0005886 (0%)" "GO:0003937 (24.9%) GO:0004643 (24.9%) GO:0042803 (0%)" "'de novo' IMP biosynthetic process (24.9%) GMP biosynthetic process (0%) 'de novo' AMP biosynthetic process (0%)" "cytosol (24.9%) ribosome (0%) plasma membrane (0%)" "IMP cyclohydrolase activity (24.9%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (24.9%) protein homodimerization activity (0%)" "IPR002695 (24.9%) IPR016193 (24.8%) IPR024051 (24.8%)" "Bifunctional purine biosynthesis protein PurH-like (24.9%) Cytidine deaminase-like (24.8%) AICAR transformylase, duplicated domain superfamily (24.8%)" KNEPVEWGNGLYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (25%) GO:0071555 (25%)" "GO:0016758 (25%) GO:0016798 (25%)" "carbohydrate metabolic process (25%) cell wall organization (25%)" "hexosyltransferase activity (25%) hydrolase activity, acting on glycosyl bonds (25%)" "IPR007184 (34.3%) IPR028583 (34.3%) IPR023296 (31.3%)" "Mannoside phosphorylase (34.3%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (34.3%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (31.3%)" TSYTASYSSTGTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025366 (100%) Protein of unknown function DUF4270 (100%) KYANPTLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (16.5%) GO:0006096 (12.7%) GO:0030388 (12.7%)" "GO:0008270 (29.1%) GO:0016832 (15.2%) GO:0004332 (13.9%)" "carbohydrate metabolic process (16.5%) glycolytic process (12.7%) fructose 1,6-bisphosphate metabolic process (12.7%)" "zinc ion binding (29.1%) aldehyde-lyase activity (15.2%) fructose-bisphosphate aldolase activity (13.9%)" "IPR000771 (29.1%) IPR013785 (29.1%) IPR050246 (29.1%)" "Fructose-bisphosphate aldolase, class-II (29.1%) Aldolase-type TIM barrel (29.1%) Class II Fructose-bisphosphate Aldolase (29.1%)" AATVLVPDSYGYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NFGGVPLVMSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LVYDGHENQPTLEGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20%) IPR013320 (20%) IPR023296 (20%)" "Glycoside hydrolase, family 43 (20%) Concanavalin A-like lectin/glucanase domain superfamily (20%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (20%)" YAGTDGQNVYAGTYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GVTEAWTQHYAVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR033985 (36.4%) IPR011990 (27.3%)" "RagB/SusD domain (36.4%) SusD-like, N-terminal (36.4%) Tetratricopeptide-like helical domain superfamily (27.3%)" DLNLVYSAMHGTGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.9%) IPR016066 (14.9%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.9%) Alpha-D-phosphohexomutase, conserved site (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" LASYADVYVMDAFGTAHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" NLLDSETLYHNQEALKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.7%) GO:0005829 (16.7%) "GO:0003723 (16.7%) GO:0004831 (16.7%) GO:0005524 (16.7%)" tyrosyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "RNA binding (16.7%) tyrosine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (12.7%) IPR002305 (12.7%) IPR002307 (12.7%)" "Aminoacyl-tRNA synthetase, class I, conserved site (12.7%) Aminoacyl-tRNA synthetase, class Ic (12.7%) Tyrosine-tRNA ligase (12.7%)" LLATSNDPAEAYEAARK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005737 (20%) GO:0015935 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "cytoplasm (20%) small ribosomal subunit (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR001209 (33.3%) IPR018271 (33.3%) IPR023036 (33.3%)" "Small ribosomal subunit protein uS14 (33.3%) Small ribosomal subunit protein uS14, conserved site (33.3%) Small ribosomal subunit protein uS14, bacteria/plastid (33.3%)" KAEFFLPLMVNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016740 (100%) transferase activity (100%) "IPR029044 (86.4%) IPR005835 (13.6%)" "Nucleotide-diphospho-sugar transferases (86.4%) Nucleotidyl transferase domain (13.6%)" VFEFTNR root "4.1.2.14 (48.9%) 4.1.3.16 (45.4%) 4.1.3.42 (3.2%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (48.9%) 4-hydroxy-2-oxoglutarate aldolase (45.4%) (4S)-4-hydroxy-2-oxoglutarate aldolase (3.2%)" "GO:0006364 (1%) GO:0000272 (0.2%) GO:0006357 (0.2%)" "GO:0005737 (1%) GO:0016020 (0.7%) GO:0005576 (0.2%)" "GO:0016829 (61.7%) GO:0008675 (12.1%) GO:0008700 (11.2%)" "rRNA processing (1%) polysaccharide catabolic process (0.2%) regulation of transcription by RNA polymerase II (0.2%)" "cytoplasm (1%) membrane (0.7%) extracellular region (0.2%)" "lyase activity (61.7%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (12.1%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (11.2%)" "IPR000887 (41.8%) IPR013785 (41.8%) IPR000192 (1%)" "KDPG/KHG aldolase (41.8%) Aldolase-type TIM barrel (41.8%) Aminotransferase class V domain (1%)" NNELLTGLK root GO:0005886 (33.6%) "GO:0042910 (33.6%) GO:0008324 (32.8%)" plasma membrane (33.6%) "xenobiotic transmembrane transporter activity (33.6%) monoatomic cation transmembrane transporter activity (32.8%)" "IPR001036 (34.2%) IPR004763 (33.3%) IPR027463 (32.5%)" "Acriflavin resistance protein (34.2%) Cation efflux system CusA-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (32.5%)" WEVPGVAYPLYYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004674 (100%) protein serine/threonine kinase activity (100%) "IPR024361 (22.4%) IPR013783 (21.2%) IPR032675 (21.2%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (22.4%) Immunoglobulin-like fold (21.2%) Leucine-rich repeat domain superfamily (21.2%)" HVNPNDNEACAEALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AVFGLDHQLWSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20%) IPR012910 (20%) IPR036942 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" GNLVDGTGEPLLGATVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.7%) IPR023996 (15.7%) IPR023997 (15.7%)" "TonB-dependent receptor, plug domain (15.7%) TonB-dependent outer membrane protein, SusC/RagA (15.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.7%)" QTCDFSVFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.14.- (100%) Dipeptidyl-peptidases and tripeptidyl-peptidases (100%) "GO:0006508 (24.8%) GO:0043171 (24.8%)" GO:0016020 (0.6%) "GO:0008239 (25%) GO:0070009 (25%)" "proteolysis (24.8%) peptide catabolic process (24.8%)" membrane (0.6%) "dipeptidyl-peptidase activity (25%) serine-type aminopeptidase activity (25%)" "IPR019500 (33.9%) IPR009003 (33.2%) IPR043504 (32.9%)" "Peptidase S46 (33.9%) Peptidase S1, PA clan (33.2%) Peptidase S1, PA clan, chymotrypsin-like fold (32.9%)" ATAQVEAQLGEALGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20%) IPR008753 (20%) IPR018497 (20%)" "Peptidase M13 (20%) Peptidase M13, N-terminal domain (20%) Peptidase M13, C-terminal domain (20%)" WGELEVCSDEYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (15.1%) GO:0009098 (15.1%) GO:0009099 (15.1%)" "GO:0004084 (19%) GO:0052654 (5.6%) GO:0052655 (5.6%)" "isoleucine biosynthetic process (15.1%) L-leucine biosynthetic process (15.1%) L-valine biosynthetic process (15.1%)" "branched-chain-amino-acid transaminase activity (19%) L-leucine-2-oxoglutarate transaminase activity (5.6%) L-valine-2-oxoglutarate transaminase activity (5.6%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" SGETEDTTLADLAVATNSGQLK Bacteria Bacteria 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.6%) GO:0009986 (16.4%)" "GO:0000287 (16.7%) GO:0004634 (16.7%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.6%) cell surface (16.4%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%)" "IPR000941 (16.8%) IPR020810 (16.8%) IPR036849 (16.8%)" "Enolase (16.8%) Enolase, C-terminal TIM barrel domain (16.8%) Enolase-like, C-terminal domain superfamily (16.8%)" NFGDNLVEDQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.4%) GO:0022627 (20.4%) "GO:0003735 (20.4%) GO:0019843 (20.4%) GO:0003729 (18.5%)" translation (20.4%) cytosolic small ribosomal subunit (20.4%) "structural constituent of ribosome (20.4%) rRNA binding (20.4%) mRNA binding (18.5%)" "IPR001351 (11%) IPR004044 (11%) IPR004087 (11%)" "Small ribosomal subunit protein uS3, C-terminal (11%) K Homology domain, type 2 (11%) K Homology domain (11%)" AYLVNTGWNGTGKR root 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.5%) "GO:0005829 (17.5%) GO:0005737 (0%)" "GO:0004612 (17.5%) GO:0005524 (17.5%) GO:0046872 (16.8%)" gluconeogenesis (17.5%) "cytosol (17.5%) cytoplasm (0%)" "phosphoenolpyruvate carboxykinase (ATP) activity (17.5%) ATP binding (17.5%) metal ion binding (16.8%)" "IPR001272 (25.4%) IPR013035 (25.4%) IPR015994 (24.6%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.4%) Phosphoenolpyruvate carboxykinase, C-terminal (25.4%) Phosphoenolpyruvate carboxykinase (ATP), conserved site (24.6%)" LYNVFCYDYLYPNPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.8%) IPR015171 (14.8%) IPR019492 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Cyclomaltodextrinase, N-terminal (14.8%) Cyclo-malto-dextrinase, C-terminal (14.8%)" HQSQMESAPFLGNDER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0006044 (32.3%) GO:0005975 (32.2%)" "GO:0004342 (32.6%) GO:0016853 (2.3%) GO:0016787 (0.7%)" "N-acetylglucosamine metabolic process (32.3%) carbohydrate metabolic process (32.2%)" "glucosamine-6-phosphate deaminase activity (32.6%) isomerase activity (2.3%) hydrolase activity (0.7%)" "IPR052960 (16.5%) IPR024078 (16.3%) IPR003737 (15.8%)" "Glucosamine-6-phosphate deaminase-like (16.5%) Putative deacetylase LmbE-like domain superfamily (16.3%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (15.8%)" KSSFTGSAAVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (27.9%) GO:0009279 (44.2%) GO:0015344 (27.9%) siderophore transmembrane transport (27.9%) cell outer membrane (44.2%) siderophore uptake transmembrane transporter activity (27.9%) "IPR012910 (14.5%) IPR023996 (14.5%) IPR023997 (14.5%)" "TonB-dependent receptor, plug domain (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.5%)" AVEADLDANKGYLPVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016787 (50%) carbohydrate metabolic process (50%) hydrolase activity (50%) "IPR012878 (17%) IPR049046 (17%) IPR049049 (17%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17%)" MGVPLVFFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25%) IPR046335 (25%) IPR010982 (23.7%)" "LacI-type HTH domain (25%) Transcriptional regulator LacI/GalR-like, sensor domain (25%) Lambda repressor-like, DNA-binding domain superfamily (23.7%)" WMDYGKDHYATVTFDNAPEGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" KYMDECGAANFFGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (13.5%) GO:0009098 (13.5%) GO:0009099 (13.5%)" "GO:0004084 (20.5%) GO:0052654 (4.9%) GO:0052655 (4.9%)" "isoleucine biosynthetic process (13.5%) L-leucine biosynthetic process (13.5%) L-valine biosynthetic process (13.5%)" "branched-chain-amino-acid transaminase activity (20.5%) L-leucine-2-oxoglutarate transaminase activity (4.9%) L-valine-2-oxoglutarate transaminase activity (4.9%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" VQFGSVDEVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" MYSSYDVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.7%) IPR004134 (33.7%) IPR038765 (32.7%)" "Cysteine peptidase, cysteine active site (33.7%) Peptidase C1B, bleomycin hydrolase (33.7%) Papain-like cysteine peptidase superfamily (32.7%)" FEAFAPATLPNTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (80%) GO:0015344 (20%) cell outer membrane (80%) siderophore uptake transmembrane transporter activity (20%) "IPR036942 (80%) IPR039426 (20%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (80%) TonB-dependent receptor-like (20%)" ASSVAHLGALDLGGDNPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.17.7.3 (100%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (100%) "GO:0016114 (19.1%) GO:0019288 (19.1%)" "GO:0046429 (19.1%) GO:0051539 (19.1%) GO:0005506 (17.6%)" "terpenoid biosynthetic process (19.1%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (19.1%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (19.1%) 4 iron, 4 sulfur cluster binding (19.1%) iron ion binding (17.6%)" "IPR004588 (26.5%) IPR011005 (25%) IPR017178 (24.3%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (26.5%) Dihydropteroate synthase-like superfamily (25%) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, atypical (24.3%)" GGMSEFQQWVDAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) VYCSLDDFFTLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.4%) IPR036942 (14.4%) IPR008969 (13.9%)" "TonB-dependent outer membrane protein, SusC/RagA (14.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.4%) Carboxypeptidase-like, regulatory domain superfamily (13.9%)" VLLNGLGK root "4.2.3.4 (37.5%) 1.1.1.30 (25%) 2.3.1.286 (12.5%)" "3-dehydroquinate synthase (37.5%) 3-hydroxybutyrate dehydrogenase (25%) protein acetyllysine N-acetyltransferase (12.5%)" "GO:0005975 (3.4%) GO:0006629 (2.3%) GO:0032787 (2.3%)" "GO:0016020 (5.7%) GO:0005576 (2.3%) GO:0005737 (2.3%)" "GO:0003723 (3.4%) GO:0005524 (3.4%) GO:0003858 (2.3%)" "carbohydrate metabolic process (3.4%) lipid metabolic process (2.3%) monocarboxylic acid metabolic process (2.3%)" "membrane (5.7%) extracellular region (2.3%) cytoplasm (2.3%)" "RNA binding (3.4%) ATP binding (3.4%) 3-hydroxybutyrate dehydrogenase activity (2.3%)" "IPR025964 (84.7%) IPR009880 (0.9%) IPR011043 (0.9%)" "GGGtGRT protein (84.7%) Glyoxal oxidase, N-terminal (0.9%) Galactose oxidase/kelch, beta-propeller (0.9%)" NSSYHGYATTNYYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (15.3%) IPR015171 (14.7%) IPR019492 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (15.3%) Cyclomaltodextrinase, N-terminal (14.7%) Cyclo-malto-dextrinase, C-terminal (14.7%)" LVAFDLPK root "2.7.7.8 (75.6%) 1.2.7.4 (12.2%) 2.6.1.62 (4.9%)" "polyribonucleotide nucleotidyltransferase (75.6%) anaerobic carbon-monoxide dehydrogenase (12.2%) adenosylmethionine--8-amino-7-oxononanoate transaminase (4.9%)" "GO:0006396 (8.8%) GO:0006402 (8.8%) GO:0032259 (2.1%)" "GO:0005829 (8.8%) GO:0016020 (2.1%) GO:1990204 (1.8%)" "GO:0000175 (8.8%) GO:0000287 (8.8%) GO:0003723 (8.8%)" "RNA processing (8.8%) mRNA catabolic process (8.8%) methylation (2.1%)" "cytosol (8.8%) membrane (2.1%) oxidoreductase complex (1.8%)" "3'-5'-RNA exonuclease activity (8.8%) magnesium ion binding (8.8%) RNA binding (8.8%)" "IPR012340 (6%) IPR001247 (5.8%) IPR003029 (5.8%)" "Nucleic acid-binding, OB-fold (6%) Exoribonuclease, phosphorolytic domain 1 (5.8%) S1 domain (5.8%)" WSAFDNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VLDAPSLEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.2%) "GO:0005524 (25.2%) GO:0042802 (24.4%) GO:0004713 (17.9%)" plasma membrane (25.2%) "ATP binding (25.2%) identical protein binding (24.4%) protein tyrosine kinase activity (17.9%)" "IPR005702 (16.8%) IPR025669 (16.8%) IPR032807 (16.8%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%) Tyrosine-protein kinase, G-rich domain (16.8%)" QDYGLDLNFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (11.8%) IPR012910 (11.8%) IPR023996 (11.8%)" "Carboxypeptidase-like, regulatory domain superfamily (11.8%) TonB-dependent receptor, plug domain (11.8%) TonB-dependent outer membrane protein, SusC/RagA (11.8%)" KNAAVLADDLLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (16.9%) GO:0035999 (16.9%) GO:0032259 (7.8%)" GO:0005829 (16.9%) "GO:0004372 (16.9%) GO:0030170 (16.9%) GO:0008168 (7.8%)" "glycine biosynthetic process from serine (16.9%) tetrahydrofolate interconversion (16.9%) methylation (7.8%)" cytosol (16.9%) "glycine hydroxymethyltransferase activity (16.9%) pyridoxal phosphate binding (16.9%) methyltransferase activity (7.8%)" "IPR001085 (14.3%) IPR015421 (14.3%) IPR015422 (14.3%)" "Serine hydroxymethyltransferase (14.3%) Pyridoxal phosphate-dependent transferase, major domain (14.3%) Pyridoxal phosphate-dependent transferase, small domain (14.3%)" ETGRVDYDEMEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (17.1%) GO:0035999 (17.1%) GO:0032259 (7.3%)" GO:0005829 (17.1%) "GO:0004372 (17.1%) GO:0030170 (17.1%) GO:0008168 (7.3%)" "glycine biosynthetic process from serine (17.1%) tetrahydrofolate interconversion (17.1%) methylation (7.3%)" cytosol (17.1%) "glycine hydroxymethyltransferase activity (17.1%) pyridoxal phosphate binding (17.1%) methyltransferase activity (7.3%)" "IPR001085 (14.5%) IPR019798 (14.5%) IPR039429 (14.5%)" "Serine hydroxymethyltransferase (14.5%) Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.5%) Serine hydroxymethyltransferase-like domain (14.5%)" EDAEGLDLLVPAYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005146 (7.9%) IPR005147 (7.9%) IPR045060 (7.9%)" "B3/B4 tRNA-binding domain (7.9%) tRNA synthetase, B5-domain (7.9%) Phenylalanine-tRNA ligase, class IIc, beta subunit (7.9%)" EVSFDLTPDMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR026891 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Fibronectin type III-like domain (11.5%)" LSDEAWMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" YLELTEGYLTK Bacteria Bacteria GO:0016226 (33.3%) "GO:0005506 (33.3%) GO:0051536 (33.3%)" iron-sulfur cluster assembly (33.3%) "iron ion binding (33.3%) iron-sulfur cluster binding (33.3%)" IPR002871 (100%) NIF system FeS cluster assembly, NifU, N-terminal (100%) KLGFEGGQMPLQR root GO:0006412 (25.2%) "GO:0022625 (25.2%) GO:0005840 (0%)" "GO:0003735 (25.2%) GO:0019843 (24.3%)" translation (25.2%) "cytosolic large ribosomal subunit (25.2%) ribosome (0%)" "structural constituent of ribosome (25.2%) rRNA binding (24.3%)" "IPR005749 (20.4%) IPR030878 (20.3%) IPR021131 (20.3%)" "Large ribosomal subunit protein uL15, bacteria (20.4%) Large ribosomal subunit protein uL15 (20.3%) Large ribosomal subunit protein uL15/eL18 (20.3%)" NQYADLMER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "1.1.1.3 (50.8%) 2.7.2.4 (49.2%)" "homoserine dehydrogenase (50.8%) aspartate kinase (49.2%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" FKDLTYDELYTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.4.22 (100%) UMP kinase (100%) "GO:0006225 (20%) GO:0044210 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0033862 (20%)" "UDP biosynthetic process (20%) 'de novo' CTP biosynthetic process (20%)" cytoplasm (20%) "ATP binding (20%) UMP kinase activity (20%)" "IPR001048 (26.7%) IPR015963 (26.7%) IPR011817 (23.3%)" "Aspartate/glutamate/uridylate kinase (26.7%) Uridylate kinase, bacteria (26.7%) Uridylate kinase (23.3%)" LVAETAMAACGLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (83.3%) IPR011250 (16.7%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (83.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16.7%)" SMFNVVNPDMLVEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) "GO:0005829 (20%) GO:0005739 (0.1%)" "GO:0004823 (20%) GO:0005524 (20%) GO:0002161 (19.7%)" leucyl-tRNA aminoacylation (20%) "cytosol (20%) mitochondrion (0.1%)" "leucine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.7%)" "IPR002302 (12.6%) IPR013155 (12.6%) IPR009080 (12.5%)" "Leucine-tRNA ligase (12.6%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.6%) Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (12.5%)" TFENLDATR root "GO:0050660 (50%) GO:0016627 (46.5%) GO:0003995 (3.5%)" "flavin adenine dinucleotide binding (50%) oxidoreductase activity, acting on the CH-CH group of donors (46.5%) acyl-CoA dehydrogenase activity (3.5%)" "IPR006091 (10%) IPR009075 (10%) IPR013786 (10%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (10%) Acyl-CoA dehydrogenase/oxidase, C-terminal (10%) Acyl-CoA dehydrogenase/oxidase, N-terminal (10%)" VMSDLLDDKVLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004818 (16.7%) GO:0005524 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR000924 (10%) IPR001412 (10%) IPR004527 (10%)" "Glutamyl/glutaminyl-tRNA synthetase (10%) Aminoacyl-tRNA synthetase, class I, conserved site (10%) Glutamate-tRNA ligase, bacterial/mitochondrial (10%)" QLAQATFAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009228 (24.6%) "GO:0051539 (26.2%) GO:0003824 (24.6%) GO:0005506 (24.6%)" thiamine biosynthetic process (24.6%) "4 iron, 4 sulfur cluster binding (26.2%) catalytic activity (24.6%) iron ion binding (24.6%)" "IPR010722 (20.8%) IPR034428 (20.8%) IPR007197 (19.5%)" "Biotin and thiamin synthesis-associated domain (20.8%) ThiH/NocL/HydG-like (20.8%) Radical SAM (19.5%)" SVNLGLLK root "1.4.1.4 (91.8%) 4.1.2.4 (2.2%) 1.4.1.2 (1.6%)" "glutamate dehydrogenase (NADP(+)) (91.8%) deoxyribose-phosphate aldolase (2.2%) glutamate dehydrogenase (1.6%)" "GO:0006537 (23.4%) GO:0006018 (0.1%) GO:0006397 (0.1%)" "GO:0005829 (23.4%) GO:0016020 (0.3%) GO:0005737 (0.1%)" "GO:0004354 (23.4%) GO:0000166 (21.6%) GO:0004352 (5.7%)" "glutamate biosynthetic process (23.4%) 2-deoxyribose 1-phosphate catabolic process (0.1%) mRNA processing (0.1%)" "cytosol (23.4%) membrane (0.3%) cytoplasm (0.1%)" "glutamate dehydrogenase (NADP+) activity (23.4%) nucleotide binding (21.6%) glutamate dehydrogenase (NAD+) activity (5.7%)" "IPR006097 (11.1%) IPR050724 (11.1%) IPR046346 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%) Glutamate/Leucine/Phenylalanine/Valine dehydrogenases (11.1%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (11.1%)" WALEHCKDDLAFLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.8%) GO:0005737 (18.8%) "GO:0005524 (20.8%) GO:0003676 (18.8%) GO:0004816 (18.8%)" asparaginyl-tRNA aminoacylation (20.8%) cytoplasm (18.8%) "ATP binding (20.8%) nucleic acid binding (18.8%) asparagine-tRNA ligase activity (18.8%)" "IPR004364 (15.6%) IPR006195 (14.8%) IPR045864 (14.8%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (15.6%) Aminoacyl-tRNA synthetase, class II (14.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.8%)" AEGGYSFLDLGNDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010221 (100%) VCBS domain (100%) YVCDGGTFADDDLRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.3%) IPR023996 (15.3%) IPR023997 (15.3%)" "TonB-dependent receptor, plug domain (15.3%) TonB-dependent outer membrane protein, SusC/RagA (15.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.3%)" AKLEDTPLDER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0017038 (11.4%) GO:0006605 (11%) GO:0043952 (11%)" "GO:0005829 (11%) GO:0005886 (11%) GO:0031522 (11%)" "GO:0005524 (11.4%) GO:0046872 (10.7%)" "protein import (11.4%) protein targeting (11%) protein transport by the Sec complex (11%)" "cytosol (11%) plasma membrane (11%) cell envelope Sec protein transport complex (11%)" "ATP binding (11.4%) metal ion binding (10.7%)" "IPR011115 (8%) IPR014018 (8%) IPR000185 (7.8%)" "SecA DEAD-like, N-terminal (8%) SecA motor DEAD (8%) Protein translocase subunit SecA (7.8%)" LEELGASYALGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.4%) IPR018223 (14.4%) IPR023434 (14.4%)" "Argininosuccinate synthase (14.4%) Argininosuccinate synthase, conserved site (14.4%) Argininosuccinate synthase, type 1 subfamily (14.4%)" RSFLDYQDNLYSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.8%) IPR034982 (33.8%) IPR038352 (32.3%)" "Imelysin-like domain (33.8%) Iron-regulated protein A, imelysin-like domain (33.8%) Imelysin-like domain superfamily (32.3%)" GLLQLPLTELGLSHGLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" EFGVPLVNK Bacteria Bacteria IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) GFADCLSNGVLGGFPMTGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20.3%) GO:0005737 (19.5%) "GO:0003746 (20.3%) GO:0005525 (20.3%) GO:0003924 (19.5%)" ribosome disassembly (20.3%) cytoplasm (19.5%) "translation elongation factor activity (20.3%) GTP binding (20.3%) GTPase activity (19.5%)" "IPR000640 (6.5%) IPR004161 (6.5%) IPR005517 (6.5%)" "Elongation factor EFG, domain V-like (6.5%) Translation elongation factor EFTu-like, domain 2 (6.5%) Translation elongation factor EFG/EF2, domain IV (6.5%)" DVTLFDGNDQSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (16.8%) IPR019998 (16.8%) IPR028053 (16.8%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (16.8%) Membrane insertase YidC (16.8%) Membrane insertase YidC, N-terminal (16.8%)" GNYLTFLTADHGGVNNATFLQDQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.1 (100%) alkaline phosphatase (100%) GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.3%) IPR026263 (34.3%) IPR017850 (31.4%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.3%) Alkaline phosphatase, prokaryotic (34.3%) Alkaline-phosphatase-like, core domain superfamily (31.4%)" LPQEVLER root "2.1.1.137 (25.9%) 4.2.1.33 (17.2%) 2.6.1.52 (13.8%)" "arsenite methyltransferase (25.9%) 3-isopropylmalate dehydratase (17.2%) phosphoserine transaminase (13.8%)" "GO:0032259 (3.3%) GO:0051781 (1.6%) GO:0051897 (1.6%)" "GO:0005737 (4.9%) GO:0016020 (2.6%) GO:0005829 (1.9%)" "GO:0005524 (4.5%) GO:0008168 (3.5%) GO:0016747 (2.1%)" "methylation (3.3%) positive regulation of cell division (1.6%) positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (1.6%)" "cytoplasm (4.9%) membrane (2.6%) cytosol (1.9%)" "ATP binding (4.5%) methyltransferase activity (3.5%) acyltransferase activity, transferring groups other than amino-acyl groups (2.1%)" "IPR011989 (3.3%) IPR029063 (3.3%) IPR016024 (3.1%)" "Armadillo-like helical (3.3%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (3.3%) Armadillo-type fold (3.1%)" TGLVPDEDTGTLFACLSTAPGTSQER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009636 (24.2%) GO:0005886 (25.5%) "GO:0042910 (25.5%) GO:0015562 (24.8%)" response to toxic substance (24.2%) plasma membrane (25.5%) "xenobiotic transmembrane transporter activity (25.5%) efflux transmembrane transporter activity (24.8%)" "IPR001036 (33.9%) IPR004764 (33%) IPR027463 (33%)" "Acriflavin resistance protein (33.9%) Multidrug resistance protein MdtF-like (33%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33%)" NMETGEQTLVTAEELLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "6.1.1.21 (94.1%) 6.1.1.- (5.9%)" "histidine--tRNA ligase (94.1%) Ligases forming aminoacyl-tRNA and related compounds (5.9%)" GO:0006427 (24.2%) GO:0005737 (24.2%) "GO:0004821 (25.8%) GO:0005524 (24.2%) GO:0016874 (1.6%)" histidyl-tRNA aminoacylation (24.2%) cytoplasm (24.2%) "histidine-tRNA ligase activity (25.8%) ATP binding (24.2%) ligase activity (1.6%)" "IPR004154 (13.4%) IPR036621 (13.4%) IPR033656 (12.6%)" "Anticodon-binding (13.4%) Anticodon-binding domain superfamily (13.4%) Histidyl-anticodon-binding (12.6%)" LAGLTNMSNYTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.5%) "GO:0004556 (32.3%) GO:0043169 (32.3%)" carbohydrate metabolic process (35.5%) "alpha-amylase activity (32.3%) cation binding (32.3%)" "IPR006047 (35.5%) IPR006046 (32.3%) IPR017853 (32.3%)" "Glycosyl hydrolase family 13, catalytic domain (35.5%) Alpha amylase (32.3%) Glycoside hydrolase superfamily (32.3%)" LEDQVYQEMQTLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (32.3%) GO:0045259 (32.3%)" "GO:0046933 (32.3%) GO:0016787 (3.2%)" "plasma membrane (32.3%) proton-transporting ATP synthase complex (32.3%)" "proton-transporting ATP synthase activity, rotational mechanism (32.3%) hydrolase activity (3.2%)" "IPR000711 (50%) IPR026015 (50%)" "ATPase, OSCP/delta subunit (50%) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily (50%)" VKELYMEGFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR011990 (33%) IPR033985 (33%)" "RagB/SusD domain (34.1%) Tetratricopeptide-like helical domain superfamily (33%) SusD-like, N-terminal (33%)" VTLSPNGGDFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (59.1%) "GO:0016787 (31.8%) GO:0016829 (9.1%)" carbohydrate metabolic process (59.1%) "hydrolase activity (31.8%) lyase activity (9.1%)" "IPR013783 (25.4%) IPR031965 (25.4%) IPR006047 (22%)" "Immunoglobulin-like fold (25.4%) Starch-binding module 26 (25.4%) Glycosyl hydrolase family 13, catalytic domain (22%)" EAPKFDELSTHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (22%) GO:0045259 (22%)" "GO:0005524 (22%) GO:0046933 (22%) GO:0016787 (12.2%)" "plasma membrane (22%) proton-transporting ATP synthase complex (22%)" "ATP binding (22%) proton-transporting ATP synthase activity, rotational mechanism (22%) hydrolase activity (12.2%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" SVASLGLDLAGQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" SSFTGSAAVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (27.9%) GO:0009279 (44.2%) GO:0015344 (27.9%) siderophore transmembrane transport (27.9%) cell outer membrane (44.2%) siderophore uptake transmembrane transporter activity (27.9%) "IPR012910 (14.5%) IPR023996 (14.5%) IPR023997 (14.5%)" "TonB-dependent receptor, plug domain (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.5%)" LDPLKYDLLFER root 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006260 (24.4%) GO:0016539 (0.2%) GO:0006811 (0%)" "GO:0005737 (10.3%) GO:0016020 (0%)" "GO:0008408 (24.4%) GO:0003887 (23.9%) GO:0003676 (16.4%)" "DNA replication (24.4%) intein-mediated protein splicing (0.2%) monoatomic ion transport (0%)" "cytoplasm (10.3%) membrane (0%)" "3'-5' exonuclease activity (24.4%) DNA-directed DNA polymerase activity (23.9%) nucleic acid binding (16.4%)" "IPR004805 (10.9%) IPR011708 (10.9%) IPR004013 (10.7%)" "Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC (10.9%) Bacterial DNA polymerase III, alpha subunit, NTPase domain (10.9%) PHP domain (10.7%)" TGELELPEGYDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20%) IPR012910 (20%) IPR036942 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%)" ASYGEVGNDVYTVGGVAQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" GSYDGPWNLNSDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" ALQLTLAAK Pseudomonadati Bacteria Pseudomonadati 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0046373 (43%) GO:0000731 (1.2%) GO:0006261 (1.2%)" "GO:0046556 (44.2%) GO:0003677 (1.2%) GO:0005506 (1.2%)" "L-arabinose metabolic process (43%) DNA synthesis involved in DNA repair (1.2%) DNA-templated DNA replication (1.2%)" "alpha-L-arabinofuranosidase activity (44.2%) DNA binding (1.2%) iron ion binding (1.2%)" "IPR051563 (13.6%) IPR003305 (13.3%) IPR008979 (13.3%)" "Glycosyl Hydrolase Family 51 (13.6%) Carbohydrate-binding, CenC-like (13.3%) Galactose-binding-like domain superfamily (13.3%)" RGDLNSPVLVGGAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20.1%) "GO:0005840 (20.1%) GO:1990904 (20.1%)" "GO:0003735 (20.1%) GO:0019843 (18.4%) GO:0003723 (1.4%)" translation (20.1%) "ribosome (20.1%) ribonucleoprotein complex (20.1%)" "structural constituent of ribosome (20.1%) rRNA binding (18.4%) RNA binding (1.4%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" KGDHLLGDYYVAFDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%) GO:0016874 (0.2%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%) ligase activity (0.2%)" "IPR001278 (12.6%) IPR001412 (12.6%) IPR035684 (12.6%)" "Arginine-tRNA ligase (12.6%) Aminoacyl-tRNA synthetase, class I, conserved site (12.6%) Arginyl-tRNA synthetase, catalytic core domain (12.6%)" LGLDATYYNQNSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (6.1%) GO:0009279 (93.9%) iron ion transport (6.1%) cell outer membrane (93.9%) "IPR039426 (14.5%) IPR012910 (14%) IPR023996 (14%)" "TonB-dependent receptor-like (14.5%) TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%)" LYNTELGLSDNSVASLLEDYKGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (1.2%) "GO:0000155 (24.7%) GO:0003700 (24.7%) GO:0005524 (24.7%)" membrane (1.2%) "phosphorelay sensor kinase activity (24.7%) DNA-binding transcription factor activity (24.7%) ATP binding (24.7%)" "IPR001789 (7.5%) IPR003594 (7.5%) IPR003661 (7.5%)" "Signal transduction response regulator, receiver domain (7.5%) Histidine kinase/HSP90-like ATPase domain (7.5%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.5%)" LVLQTLQR root "3.1.-.- (91.3%) 2.7.13.3 (7.2%) 2.4.1.215 (0.6%)" "Acting on ester bonds (91.3%) histidine kinase (7.2%) cis-zeatin O-beta-D-glucosyltransferase (0.6%)" "GO:0006402 (18.4%) GO:0009736 (1.4%) GO:0000160 (0.2%)" "GO:0005886 (19.7%) GO:0016020 (0.3%) GO:0005737 (0.1%)" "GO:0003723 (18.8%) GO:0016787 (18.6%) GO:0004521 (18.3%)" "mRNA catabolic process (18.4%) cytokinin-activated signaling pathway (1.4%) phosphorelay signal transduction system (0.2%)" "plasma membrane (19.7%) membrane (0.3%) cytoplasm (0.1%)" "RNA binding (18.8%) hydrolase activity (18.6%) RNA endonuclease activity (18.3%)" "IPR004088 (11.3%) IPR004087 (11.3%) IPR022711 (11.3%)" "K Homology domain, type 1 (11.3%) K Homology domain (11.3%) Ribonuclease Y, N-terminal (11.3%)" SAGFPLLKDCMVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009060 (25%) GO:0022904 (25%)" "GO:0009055 (25%) GO:0051537 (25%)" "aerobic respiration (25%) respiratory electron transport chain (25%)" "electron transfer activity (25%) 2 iron, 2 sulfur cluster binding (25%)" "IPR006058 (14.1%) IPR009051 (14.1%) IPR012675 (14.1%)" "2Fe-2S ferredoxin, iron-sulphur binding site (14.1%) Alpha-helical ferredoxin (14.1%) Beta-grasp domain superfamily (14.1%)" FEPTTSFDVLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.-.-.- (50%) 1.11.1.- (50%)" "Oxidoreductases (50%) Peroxidases (50%)" GO:0034599 (50%) GO:0004601 (50%) cellular response to oxidative stress (50%) peroxidase activity (50%) "IPR000889 (35.5%) IPR036249 (35.5%) IPR029760 (29%)" "Glutathione peroxidase (35.5%) Thioredoxin-like superfamily (35.5%) Glutathione peroxidase conserved site (29%)" LDVVELPTNRPLQR Bacteria Bacteria 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.4%) GO:0017038 (11.4%) GO:0043952 (11.4%)" "GO:0005829 (11.4%) GO:0005886 (11.4%) GO:0031522 (11.4%)" "GO:0005524 (11.4%) GO:0046872 (8.4%) GO:0004386 (0.2%)" "protein targeting (11.4%) protein import (11.4%) protein transport by the Sec complex (11.4%)" "cytosol (11.4%) plasma membrane (11.4%) cell envelope Sec protein transport complex (11.4%)" "ATP binding (11.4%) metal ion binding (8.4%) helicase activity (0.2%)" "IPR000185 (8%) IPR011115 (8%) IPR014018 (8%)" "Protein translocase subunit SecA (8%) SecA DEAD-like, N-terminal (8%) SecA motor DEAD (8%)" LALVSPFK root "2.4.-.- (33.3%) 2.7.11.12 (33.3%) 6.3.1.2 (33.3%)" "Glycosyltransferases (33.3%) cGMP-dependent protein kinase (33.3%) glutamine synthetase (33.3%)" "GO:0030420 (2.9%) GO:0006542 (1.4%) GO:0006629 (1.4%)" "GO:0009279 (60.9%) GO:0005886 (4.3%) GO:0016020 (2.9%)" "GO:0000976 (1.4%) GO:0003700 (1.4%) GO:0004222 (1.4%)" "establishment of competence for transformation (2.9%) glutamine biosynthetic process (1.4%) lipid metabolic process (1.4%)" "cell outer membrane (60.9%) plasma membrane (4.3%) membrane (2.9%)" "transcription cis-regulatory region binding (1.4%) DNA-binding transcription factor activity (1.4%) metalloendopeptidase activity (1.4%)" "IPR000531 (16.5%) IPR012910 (16.5%) IPR008969 (15.7%)" "TonB-dependent receptor-like, beta-barrel (16.5%) TonB-dependent receptor, plug domain (16.5%) Carboxypeptidase-like, regulatory domain superfamily (15.7%)" EQVYDFDRQNVLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006508 (5.9%) "GO:0005886 (44.1%) GO:0098552 (44.1%)" GO:0008233 (5.9%) proteolysis (5.9%) "plasma membrane (44.1%) side of membrane (44.1%)" peptidase activity (5.9%) "IPR001107 (21.3%) IPR036013 (21.3%) IPR050710 (21.3%)" "Band 7 domain (21.3%) Band 7/SPFH domain superfamily (21.3%) Band 7/mec-2 domain-containing protein (21.3%)" DGDTVWNPGWKPCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.20 (100%) cellobiose phosphorylase (100%) GO:0005975 (32.9%) "GO:0030246 (32.9%) GO:0016757 (32.1%) GO:0016740 (1.4%)" carbohydrate metabolic process (32.9%) "carbohydrate binding (32.9%) glycosyltransferase activity (32.1%) transferase activity (1.4%)" "IPR010383 (12.8%) IPR033432 (12.8%) IPR037825 (12.8%)" "Glycosyl hydrolase 94, supersandwich domain (12.8%) Glycosyl hydrolase 94, catalytic domain (12.8%) Cellobiose phosphorylase, N-terminal (12.8%)" MLEAAMGGEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.37 (58.3%) 1.1.1.40 (41.7%)" "malate dehydrogenase (58.3%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (41.7%)" "GO:0006108 (34.1%) GO:0006089 (1.7%)" GO:0016020 (0.6%) "GO:0016615 (27.9%) GO:0016616 (27.9%) GO:0030060 (3.4%)" "malate metabolic process (34.1%) lactate metabolic process (1.7%)" membrane (0.6%) "malate dehydrogenase activity (27.9%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (27.9%) L-malate dehydrogenase (NAD+) activity (3.4%)" "IPR001236 (16.8%) IPR001557 (16.8%) IPR015955 (16.8%)" "Lactate/malate dehydrogenase, N-terminal (16.8%) L-lactate/malate dehydrogenase (16.8%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.8%)" VYGFTDFQVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.3%) GO:0006221 (13.7%) GO:0006526 (13.2%)" GO:0005737 (14.3%) "GO:0004088 (14.3%) GO:0005524 (14.3%) GO:0046872 (14.3%)" "glutamine metabolic process (14.3%) pyrimidine nucleotide biosynthetic process (13.7%) L-arginine biosynthetic process (13.2%)" cytoplasm (14.3%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.3%) ATP binding (14.3%) metal ion binding (14.3%)" "IPR005480 (10.9%) IPR005479 (10.5%) IPR011761 (10.5%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.9%) Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%)" LVDVALNELTALTGQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" ELAGSWEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" FDVEAPLLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) GO:0006221 (1.3%) "GO:0016491 (48.1%) GO:0051536 (45.5%) GO:0004355 (1.3%)" pyrimidine nucleotide biosynthetic process (1.3%) "oxidoreductase activity (48.1%) iron-sulfur cluster binding (45.5%) glutamate synthase (NADPH) activity (1.3%)" "IPR017927 (11.5%) IPR017938 (11.2%) IPR019480 (11.2%)" "FAD-binding domain, ferredoxin reductase-type (11.5%) Riboflavin synthase-like beta-barrel (11.2%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.2%)" ELFDKADELLGFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.39 (100%) [acyl-carrier-protein] S-malonyltransferase (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004314 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) [acyl-carrier-protein] S-malonyltransferase activity (33.3%) "IPR014043 (14.7%) IPR050858 (14.7%) IPR004410 (14.4%)" "Acyl transferase domain (14.7%) Malonyl CoA-ACP Transacylase/Polyketide Synthase FabD (14.7%) Malonyl CoA-acyl carrier protein transacylase, FabD-type (14.4%)" DLNPVREELEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006021 (26.1%) GO:0008654 (26.1%)" GO:0016020 (21.7%) GO:0004512 (26.1%) "inositol biosynthetic process (26.1%) phospholipid biosynthetic process (26.1%)" membrane (21.7%) inositol-3-phosphate synthase activity (26.1%) "IPR002587 (34%) IPR013021 (34%) IPR036291 (32.1%)" "Myo-inositol-1-phosphate synthase (34%) Myo-inositol-1-phosphate synthase, GAPDH-like (34%) NAD(P)-binding domain superfamily (32.1%)" GQLLLNPGSEQLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.7%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.7%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" EPMSALWAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.4%) IPR041542 (20.4%) IPR051795 (20.4%)" "Glycoside hydrolase, family 43 (20.4%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.4%) Glycosyl Hydrolase Family 43 (20.4%)" TPLEYENLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (23.6%) GO:0005886 (25.5%) "GO:0015562 (25.5%) GO:0042910 (25.5%)" response to toxic substance (23.6%) plasma membrane (25.5%) "efflux transmembrane transporter activity (25.5%) xenobiotic transmembrane transporter activity (25.5%)" "IPR001036 (34.1%) IPR004764 (34.1%) IPR027463 (31.7%)" "Acriflavin resistance protein (34.1%) Multidrug resistance protein MdtF-like (34.1%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.7%)" FGSVENPLLVSVR Bacteria Bacteria 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25.4%) GO:0016301 (25.4%) GO:0050242 (25.4%)" "ATP binding (25.4%) kinase activity (25.4%) pyruvate, phosphate dikinase activity (25.4%)" "IPR002192 (10.4%) IPR010121 (10.4%) IPR013815 (10.2%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (10.4%) Pyruvate, phosphate dikinase (10.4%) ATP-grasp fold, subdomain 1 (10.2%)" MTDPLADYLTR Bacteria Bacteria GO:0006412 (16.8%) "GO:0005840 (16.8%) GO:1990904 (16.8%) GO:0005737 (16.3%)" "GO:0003735 (16.8%) GO:0019843 (16.5%)" translation (16.8%) "ribosome (16.8%) ribonucleoprotein complex (16.8%) cytoplasm (16.3%)" "structural constituent of ribosome (16.8%) rRNA binding (16.5%)" "IPR000630 (35.1%) IPR035987 (35.1%) IPR047863 (29.8%)" "Small ribosomal subunit protein uS8 (35.1%) Small ribosomal subunit protein uS8 superfamily (35.1%) Small ribosomal subunit protein uS8, conserved site (29.8%)" YYNAALMEQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.4%) GO:0008360 (12.4%) GO:0009252 (12.4%)" GO:0005886 (12.4%) "GO:0050511 (12.4%) GO:0051991 (0.6%)" "carbohydrate metabolic process (12.4%) regulation of cell shape (12.4%) peptidoglycan biosynthetic process (12.4%)" plasma membrane (12.4%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.4%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (0.6%)" "IPR004276 (33.3%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.3%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" FQDYWANAYSENLPNNDESLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GGFSTNPYVLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (18.6%) GO:0009098 (18.6%) GO:0009099 (18.6%)" "GO:0004084 (18.8%) GO:0052654 (5%) GO:0052655 (5%)" "isoleucine biosynthetic process (18.6%) L-leucine biosynthetic process (18.6%) L-valine biosynthetic process (18.6%)" "branched-chain-amino-acid transaminase activity (18.8%) L-leucine-2-oxoglutarate transaminase activity (5%) L-valine-2-oxoglutarate transaminase activity (5%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" LAHYANAATDLEFK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.4%) GO:0044281 (0.2%)" "GO:0005737 (12.5%) GO:0070062 (12.4%) GO:1990742 (12.4%)" "GO:0004820 (12.5%) GO:0005524 (12.5%) GO:0004081 (12.4%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.4%) small molecule metabolic process (0.2%)" "cytoplasm (12.5%) extracellular exosome (12.4%) microvesicle (12.4%)" "glycine-tRNA ligase activity (12.5%) ATP binding (12.5%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.4%)" "IPR004154 (11.3%) IPR006195 (11.3%) IPR027031 (11.3%)" "Anticodon-binding (11.3%) Aminoacyl-tRNA synthetase, class II (11.3%) Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.3%)" ATTSSYVPTLYALHCFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VGSDVENLKGTATLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.8%) IPR002772 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase, family 3, N-terminal (12.8%) Glycoside hydrolase family 3 C-terminal domain (12.8%) Fibronectin type III-like domain (12.8%)" VDSLLDSDLELPAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.3.1 (100%) threonine synthase (100%) GO:0009088 (33.3%) "GO:0004795 (33.3%) GO:0030170 (33.3%)" threonine biosynthetic process (33.3%) "threonine synthase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000634 (14.5%) IPR001926 (14.5%) IPR004450 (14.5%)" "Serine/threonine dehydratase, pyridoxal-phosphate-binding site (14.5%) Tryptophan synthase beta chain-like, PALP domain (14.5%) Threonine synthase-like (14.5%)" VGMGYQGEENVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" AQYGFSELAQTNWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (3%) GO:0009279 (93.9%) GO:0015344 (3%) siderophore transmembrane transport (3%) cell outer membrane (93.9%) siderophore uptake transmembrane transporter activity (3%) "IPR012910 (12.9%) IPR023997 (12.9%) IPR039426 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%) TonB-dependent receptor-like (12.9%)" LAFTAGVR root "4.1.2.13 (73.2%) 2.7.13.3 (16.1%) 3.6.4.13 (10.7%)" "fructose-bisphosphate aldolase (73.2%) histidine kinase (16.1%) RNA helicase (10.7%)" "GO:0006096 (14.6%) GO:0030388 (14.6%) GO:0005975 (7.7%)" "GO:0005886 (2.3%) GO:0009279 (0.8%) GO:0005737 (0.3%)" "GO:0008270 (23.3%) GO:0004332 (16.1%) GO:0016832 (7.2%)" "glycolytic process (14.6%) fructose 1,6-bisphosphate metabolic process (14.6%) carbohydrate metabolic process (7.7%)" "plasma membrane (2.3%) cell outer membrane (0.8%) cytoplasm (0.3%)" "zinc ion binding (23.3%) fructose-bisphosphate aldolase activity (16.1%) aldehyde-lyase activity (7.2%)" "IPR000771 (17.6%) IPR013785 (17.6%) IPR050246 (17.6%)" "Fructose-bisphosphate aldolase, class-II (17.6%) Aldolase-type TIM barrel (17.6%) Class II Fructose-bisphosphate Aldolase (17.6%)" DCTWEQLEEVRAEVGEEDYSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (20%) GO:0005829 (20%) "GO:0004335 (20%) GO:0005524 (20%) GO:0046872 (20%)" galactose metabolic process (20%) cytosol (20%) "galactokinase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000705 (10%) IPR006203 (10%) IPR006204 (10%)" "Galactokinase (10%) GHMP kinase, ATP-binding, conserved site (10%) GHMP kinase N-terminal domain (10%)" LSGVGDVQSPSTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009636 (25%) GO:0005886 (25%) "GO:0015562 (25%) GO:0042910 (25%)" response to toxic substance (25%) plasma membrane (25%) "efflux transmembrane transporter activity (25%) xenobiotic transmembrane transporter activity (25%)" "IPR001036 (33.3%) IPR004764 (33.3%) IPR027463 (33.3%)" "Acriflavin resistance protein (33.3%) Multidrug resistance protein MdtF-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%)" EKVPGLTGLDTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006207 (15.5%) GO:0006541 (15.5%) GO:0006526 (15.3%)" "GO:0005737 (0.2%) GO:0005951 (0.2%)" "GO:0004088 (15.5%) GO:0005524 (15.3%) GO:0004359 (7%)" "'de novo' pyrimidine nucleobase biosynthetic process (15.5%) glutamine metabolic process (15.5%) L-arginine biosynthetic process (15.3%)" "cytoplasm (0.2%) carbamoyl-phosphate synthase complex (0.2%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (15.5%) ATP binding (15.3%) glutaminase activity (7%)" "IPR002474 (14.3%) IPR006274 (14.3%) IPR017926 (14.3%)" "Carbamoyl-phosphate synthase small subunit, N-terminal domain (14.3%) Carbamoyl-phosphate synthase, small subunit (14.3%) Glutamine amidotransferase (14.3%)" SLGPYSLLTQQPLGGK root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (19.9%) GO:0006508 (0.1%)" "GO:0000428 (19.9%) GO:0016020 (0%) GO:0031981 (0%)" "GO:0003677 (19.9%) GO:0003899 (19.9%) GO:0032549 (19.9%)" "DNA-templated transcription (19.9%) proteolysis (0.1%)" "DNA-directed RNA polymerase complex (19.9%) membrane (0%) nuclear lumen (0%)" "DNA binding (19.9%) DNA-directed RNA polymerase activity (19.9%) ribonucleoside binding (19.9%)" "IPR007120 (8%) IPR015712 (8%) IPR037033 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8%) DNA-directed RNA polymerase, subunit 2 (8%) DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily (7.9%)" LELSSTSHPFYTGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (24.7%) "GO:0005840 (25.1%) GO:1990904 (25.1%)" GO:0003735 (25.1%) translation (24.7%) "ribosome (25.1%) ribonucleoprotein complex (25.1%)" structural constituent of ribosome (25.1%) "IPR002150 (25%) IPR027493 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL31 type A/B (25%) Large ribosomal subunit protein bL31 type B (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" NEALQVLCTTLLTDEPVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" SPLKDELLK root 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) "GO:0009098 (16.8%) GO:0032259 (2.5%) GO:0006313 (1.9%)" "GO:0005829 (16.8%) GO:0009570 (2.5%)" "GO:0003862 (16.8%) GO:0000287 (16.1%) GO:0051287 (16.1%)" "L-leucine biosynthetic process (16.8%) methylation (2.5%) DNA transposition (1.9%)" "cytosol (16.8%) chloroplast stroma (2.5%)" "3-isopropylmalate dehydrogenase activity (16.8%) magnesium ion binding (16.1%) NAD binding (16.1%)" "IPR004429 (24.8%) IPR024084 (24.8%) IPR019818 (23.9%)" "Isopropylmalate dehydrogenase (24.8%) Isopropylmalate dehydrogenase-like domain (24.8%) Isocitrate/isopropylmalate dehydrogenase, conserved site (23.9%)" LGLLAVSR root "2.3.2.27 (59.2%) 3.1.2.6 (11.3%) 2.7.13.3 (8.5%)" "RING-type E3 ubiquitin transferase (59.2%) hydroxyacylglutathione hydrolase (11.3%) histidine kinase (8.5%)" "GO:0006004 (10.7%) GO:0006364 (0.9%) GO:0005996 (0.6%)" "GO:0016020 (12.2%) GO:0005737 (12%) GO:0005886 (3.2%)" "GO:0008736 (10.7%) GO:0008270 (7.9%) GO:0050218 (6.2%)" "fucose metabolic process (10.7%) rRNA processing (0.9%) monosaccharide metabolic process (0.6%)" "membrane (12.2%) cytoplasm (12%) plasma membrane (3.2%)" "L-fucose isomerase activity (10.7%) zinc ion binding (7.9%) propionate-CoA ligase activity (6.2%)" "IPR009015 (8.3%) IPR015888 (8%) IPR052788 (6.2%)" "L-fucose isomerase, N-terminal/central domain superfamily (8.3%) L-fucose isomerase, C-terminal (8%) RING-type E3 ubiquitin ligase ATL (6.2%)" GTAWVLDSYGYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VVVLGETGR root "1.4.1.13 (92.4%) 1.4.1.14 (4.7%) 1.4.7.1 (2.9%)" "glutamate synthase (NADPH) (92.4%) glutamate synthase (NADH) (4.7%) glutamate synthase (ferredoxin) (2.9%)" "GO:0006537 (18.8%) GO:0019676 (18.7%) GO:0048589 (0.4%)" "GO:0009536 (0.4%) GO:0005737 (0%)" "GO:0051538 (19.1%) GO:0046872 (18.7%) GO:0015930 (12.3%)" "glutamate biosynthetic process (18.8%) ammonia assimilation cycle (18.7%) developmental growth (0.4%)" "plastid (0.4%) cytoplasm (0%)" "3 iron, 4 sulfur cluster binding (19.1%) metal ion binding (18.7%) glutamate synthase activity (12.3%)" "IPR002489 (12.4%) IPR036485 (12.4%) IPR002932 (12.3%)" "Glutamate synthase, alpha subunit, C-terminal (12.4%) Glutamate synthase, alpha subunit, C-terminal domain superfamily (12.4%) Glutamate synthase domain (12.3%)" NLPCTVLEVGPCVVTQVK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000597 (25.2%) IPR009000 (25.2%) IPR019927 (25.2%)" "Large ribosomal subunit protein uL3 (25.2%) Translation protein, beta-barrel domain superfamily (25.2%) Large ribosomal subunit protein uL3, bacteria/organella (25.2%)" NGLWLSGGGALLR Pseudomonadati Bacteria Pseudomonadati "GO:0000902 (25%) GO:0008360 (25%)" GO:0005737 (25%) GO:0005524 (25%) "cell morphogenesis (25%) regulation of cell shape (25%)" cytoplasm (25%) ATP binding (25%) "IPR004753 (33.3%) IPR043129 (33.3%) IPR056546 (33.3%)" "Cell shape determining protein MreB (33.3%) ATPase, nucleotide binding domain (33.3%) MreB/MamK-like (33.3%)" TALPVCGYFLQSVFGDPAFQQYHGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.5%) GO:0016020 (0.8%)" "GO:0008658 (11.3%) GO:0008955 (11.3%) GO:0004180 (10.5%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.5%) membrane (0.8%)" "penicillin binding (11.3%) peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.5%)" "IPR001264 (17.3%) IPR001460 (17.3%) IPR050396 (17.3%)" "Glycosyl transferase, family 51 (17.3%) Penicillin-binding protein, transpeptidase (17.3%) Glycosyltransferase 51/Transpeptidase (17.3%)" AAAGNLLPSSTGAAK root "1.2.1.- (98%) 1.2.1.12 (2%)" "With NAD(+) or NADP(+) as acceptor (98%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (2%)" "GO:0006006 (22.4%) GO:0006096 (7.7%)" GO:0005829 (2.3%) "GO:0050661 (22.4%) GO:0051287 (22.4%) GO:0004365 (12.7%)" "glucose metabolic process (22.4%) glycolytic process (7.7%)" cytosol (2.3%) "NADP binding (22.4%) NAD binding (22.4%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (12.7%)" "IPR020829 (16.8%) IPR020830 (16.8%) IPR020831 (16.8%)" "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.8%) Glyceraldehyde 3-phosphate dehydrogenase, active site (16.8%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (16.8%)" CVGLLTWMHTFSPAK Bacteria Bacteria 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.2%) GO:0005829 (25.2%) "GO:0008733 (25.2%) GO:0030145 (24%) GO:0046872 (0.4%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.2%) cytosol (25.2%) "L-arabinose isomerase activity (25.2%) manganese ion binding (24%) metal ion binding (0.4%)" "IPR003762 (14.5%) IPR055389 (14.5%) IPR055390 (14.5%)" "L-arabinose isomerase (14.5%) L-arabinose isomerase, N-terminal domain (14.5%) L-arabinose isomerase, central domain (14.5%)" LLDKYNEYGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071709 (47.7%) "GO:0009279 (50%) GO:0019867 (2.3%)" membrane assembly (47.7%) "cell outer membrane (50%) outer membrane (2.3%)" "IPR010827 (25.8%) IPR034746 (25.8%) IPR039910 (24.7%)" "POTRA domain, BamA/TamA-like (25.8%) POTRA domain (25.8%) Surface antigen D15-like (24.7%)" FFLPYQLGYGER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" AYSQEAHMSLFLTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (8%) IPR002547 (7.8%) IPR004532 (7.8%)" "Phenylalanyl tRNA synthetase beta chain, core domain (8%) tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%)" RPLMSSLQGTDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000272 (31.7%) GO:0005576 (31.7%) "GO:0030570 (31.7%) GO:0004557 (4.9%)" polysaccharide catabolic process (31.7%) extracellular region (31.7%) "pectate lyase activity (31.7%) alpha-galactosidase activity (4.9%)" "IPR002022 (18.3%) IPR011050 (18.3%) IPR012334 (18.3%)" "Pectate lyase (18.3%) Pectin lyase fold/virulence factor (18.3%) Pectin lyase fold (18.3%)" FVDLEVQASNADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.5%) IPR046357 (25.5%) IPR027304 (24.5%)" "Periplasmic chaperone PpiD (26.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.5%) Trigger factor/SurA domain superfamily (24.5%)" ALLEQELEQQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" LPYLTDGEFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.14 (100%) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (100%) "GO:0009086 (25%) GO:0032259 (25%)" "GO:0003871 (25%) GO:0008270 (25%)" "methionine biosynthetic process (25%) methylation (25%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (25%) zinc ion binding (25%)" "IPR002629 (50.6%) IPR038071 (49.4%)" "Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (50.6%) UROD/MetE-like superfamily (49.4%)" VYGLNFK root "3.4.15.5 (37.5%) 3.4.-.- (12.5%) 3.4.24.- (12.5%)" "peptidyl-dipeptidase Dcp (37.5%) Acting on peptide bonds (peptidases) (12.5%) Metalloendopeptidases (12.5%)" "GO:0006508 (10.7%) GO:0006310 (0.9%) GO:0015074 (0.9%)" "GO:0043190 (14.1%) GO:0005829 (10.7%) GO:0016020 (2.2%)" "GO:0022857 (14.1%) GO:0046872 (11.2%) GO:0004180 (10.7%)" "proteolysis (10.7%) DNA recombination (0.9%) DNA integration (0.9%)" "ATP-binding cassette (ABC) transporter complex (14.1%) cytosol (10.7%) membrane (2.2%)" "transmembrane transporter activity (14.1%) metal ion binding (11.2%) carboxypeptidase activity (10.7%)" "IPR007210 (16.4%) IPR001567 (12.5%) IPR034005 (12.5%)" "ABC-type glycine betaine transport system, substrate-binding domain (16.4%) Peptidase M3A/M3B catalytic domain (12.5%) Peptidyl-dipeptidase DCP (12.5%)" QSELSNSPEVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.8.3.- (100%) CoA-transferases (100%) "GO:0006083 (31.4%) GO:0006084 (5.8%)" "GO:0003986 (31.4%) GO:0008775 (31.4%)" "acetate metabolic process (31.4%) acetyl-CoA metabolic process (5.8%)" "acetyl-CoA hydrolase activity (31.4%) acetate CoA-transferase activity (31.4%)" "IPR026888 (19.6%) IPR046433 (19.6%) IPR003702 (19.1%)" "Acetyl-CoA hydrolase/transferase, C-terminal domain (19.6%) Acetyl-CoA hydrolase/transferase (19.6%) Acetyl-CoA hydrolase/transferase, N-terminal (19.1%)" FLETYTDCQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MGDPETESVMLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20%) GO:0006189 (19.7%) GO:0006164 (0.4%)" "GO:0004637 (20%) GO:0005524 (20%) GO:0046872 (19.8%)" "purine nucleobase biosynthetic process (20%) 'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.4%)" "phosphoribosylamine-glycine ligase activity (20%) ATP binding (20%) metal ion binding (19.8%)" "IPR000115 (11.2%) IPR020560 (11.2%) IPR020561 (11.2%)" "Phosphoribosylglycinamide synthetase (11.2%) Phosphoribosylglycinamide synthetase, C-domain (11.2%) Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (11.2%)" MLQDFVPVAR Bacteria Bacteria "GO:0006004 (31.4%) GO:0005996 (2%)" GO:0005737 (33.3%) "GO:0008736 (31.4%) GO:0016861 (2%)" "fucose metabolic process (31.4%) monosaccharide metabolic process (2%)" cytoplasm (33.3%) "L-fucose isomerase activity (31.4%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (2%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" GWDGDTNMTYNPEER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" GPNHGPAPLPEEGK Bacteria Bacteria "GO:0016226 (29.4%) GO:0006879 (2.9%)" GO:0005737 (2.9%) "GO:0005506 (29.4%) GO:0051536 (29.4%) GO:0008198 (2.9%)" "iron-sulfur cluster assembly (29.4%) intracellular iron ion homeostasis (2.9%)" cytoplasm (2.9%) "iron ion binding (29.4%) iron-sulfur cluster binding (29.4%) ferrous iron binding (2.9%)" IPR002871 (100%) NIF system FeS cluster assembly, NifU, N-terminal (100%) ETLAPALQK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (19.3%) IPR020930 (19.3%) IPR022803 (19.3%)" "Large ribosomal subunit protein uL5 (19.3%) Large ribosomal subunit protein uL5, bacteria (19.3%) Large ribosomal subunit protein uL5 domain superfamily (19.3%)" EVNSYLPGEGHNLQEHSLVLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20.2%) "GO:0015935 (20.2%) GO:0005840 (0.2%)" "GO:0003735 (20.2%) GO:0019843 (20.2%) GO:0000049 (19.1%)" translation (20.2%) "small ribosomal subunit (20.2%) ribosome (0.2%)" "structural constituent of ribosome (20.2%) rRNA binding (20.2%) tRNA binding (19.1%)" "IPR005679 (33.3%) IPR006032 (33.3%) IPR012340 (33.3%)" "Ribosomal protein uS12, bacteria (33.3%) Small ribosomal subunit protein uS12 (33.3%) Nucleic acid-binding, OB-fold (33.3%)" FVFTDVAEGYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.133 (100%) dTDP-4-dehydrorhamnose reductase (100%) GO:0019305 (33.3%) GO:0005829 (33.3%) GO:0008831 (33.3%) dTDP-rhamnose biosynthetic process (33.3%) cytosol (33.3%) dTDP-4-dehydrorhamnose reductase activity (33.3%) "IPR005913 (33.8%) IPR029903 (33.8%) IPR036291 (32.3%)" "dTDP-4-dehydrorhamnose reductase family (33.8%) RmlD-like substrate binding domain (33.8%) NAD(P)-binding domain superfamily (32.3%)" TYMLSLK root "2.5.1.17 (50%) 3.1.4.52 (50%)" "corrinoid adenosyltransferase (50%) cyclic-guanylate-specific phosphodiesterase (50%)" "GO:0007156 (4%) GO:0016579 (4%) GO:0002224 (1%)" "GO:0009279 (9%) GO:0005886 (6%) GO:0005634 (5%)" "GO:0004843 (4%) GO:0005524 (4%) GO:0003676 (1%)" "homophilic cell-cell adhesion (4%) protein deubiquitination (4%) toll-like receptor signaling pathway (1%)" "cell outer membrane (9%) plasma membrane (6%) nucleus (5%)" "cysteine-type deubiquitinase activity (4%) ATP binding (4%) nucleic acid binding (1%)" "IPR008969 (3.3%) IPR012910 (3.3%) IPR013783 (3.3%)" "Carboxypeptidase-like, regulatory domain superfamily (3.3%) TonB-dependent receptor, plug domain (3.3%) Immunoglobulin-like fold (3.3%)" SMGMPEHLLTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (32.9%) "GO:0003921 (32.9%) GO:0005524 (32.9%) GO:0016740 (1.3%)" cytosol (32.9%) "GMP synthase activity (32.9%) ATP binding (32.9%) transferase activity (1.3%)" "IPR001674 (13%) IPR025777 (13%) IPR004739 (12.4%)" "GMP synthase, C-terminal (13%) GMP synthetase ATP pyrophosphatase domain (13%) GMP synthase, glutamine amidotransferase (12.4%)" EVGPNPGQACVVPGHQLAEMALCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (49.2%) GO:0016787 (50.8%) carbohydrate metabolic process (49.2%) hydrolase activity (50.8%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" FFESESLTEDELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (7.9%) IPR005225 (7.9%) IPR041095 (7.9%)" "Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%) Elongation Factor G, domain II (7.9%)" AAYALGGLGSGFADNEEELNKLAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (96.6%) 6.3.4.16 (3.4%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (96.6%) carbamoyl-phosphate synthase (ammonia) (3.4%)" "GO:0006541 (14.3%) GO:0006221 (13.4%) GO:0006526 (13.4%)" GO:0005737 (14.3%) "GO:0004088 (14.3%) GO:0005524 (14.3%) GO:0046872 (14.3%)" "glutamine metabolic process (14.3%) pyrimidine nucleotide biosynthetic process (13.4%) L-arginine biosynthetic process (13.4%)" cytoplasm (14.3%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.3%) ATP binding (14.3%) metal ion binding (14.3%)" "IPR005479 (10.7%) IPR011761 (10.7%) IPR005480 (10.4%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.7%) ATP-grasp fold (10.7%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.4%)" AYLFYSGYYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" TYDMSGFAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (43.5%) "GO:0015926 (43.5%) GO:0031218 (13%)" pectin catabolic process (43.5%) "glucosidase activity (43.5%) arabinogalactan endo-1,4-beta-galactosidase activity (13%)" "IPR011683 (51.3%) IPR017853 (48.7%)" "Glycosyl hydrolase family 53 (51.3%) Glycoside hydrolase superfamily (48.7%)" QDEGDEMFGSSSAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0035435 (33.3%) GO:0016020 (33.3%) GO:0005315 (33.3%) phosphate ion transmembrane transport (33.3%) membrane (33.3%) phosphate transmembrane transporter activity (33.3%) IPR001204 (100%) Phosphate transporter (100%) TLASHSLCLFGDHQDVMACR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.2.7.1 (88.9%) 1.2.7.- (11.1%)" "pyruvate synthase (88.9%) With an iron-sulfur protein as acceptor (11.1%)" "GO:0006979 (14.5%) GO:0022900 (14.5%) GO:0044281 (13%)" "GO:0005506 (14.5%) GO:0030976 (14.5%) GO:0051539 (14.5%)" "response to oxidative stress (14.5%) electron transport chain (14.5%) small molecule metabolic process (13%)" "iron ion binding (14.5%) thiamine pyrophosphate binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" KTGLDPLAFVSPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.3.1.191 (96.4%) 2.3.1.- (3.6%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (96.4%) Transferring groups other than amino-acyl groups (3.6%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20.1%) IPR007691 (20.1%) IPR011004 (20.1%)" "Hexapeptide repeat (20.1%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20.1%) Trimeric LpxA-like superfamily (20.1%)" SYGGSHLVMGCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.-.-.- (100%) Ligases (100%) "GO:0015977 (21.1%) GO:0006633 (4.1%)" GO:0009317 (21.1%) "GO:0004658 (22.2%) GO:0003989 (21.1%) GO:0016740 (8.9%)" "carbon fixation (21.1%) fatty acid biosynthetic process (4.1%)" acetyl-CoA carboxylase complex (21.1%) "propionyl-CoA carboxylase activity (22.2%) acetyl-CoA carboxylase activity (21.1%) transferase activity (8.9%)" "IPR011762 (19.4%) IPR011763 (19.4%) IPR034733 (19.4%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.4%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.4%)" SSLDKFYSPEELAELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20.2%) GO:0005737 (20.2%) "GO:0004815 (20.2%) GO:0005524 (20.2%) GO:0003676 (19.4%)" aspartyl-tRNA aminoacylation (20.2%) cytoplasm (20.2%) "aspartate-tRNA ligase activity (20.2%) ATP binding (20.2%) nucleic acid binding (19.4%)" "IPR004364 (9.5%) IPR002312 (9.1%) IPR004115 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.5%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%)" KGDVLLVAGK Bacteria Bacteria 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.4%) GO:0051301 (12.4%) GO:0009252 (12.3%)" GO:0005737 (12.4%) "GO:0005524 (12.5%) GO:0000287 (12.3%) GO:0008765 (12.3%)" "regulation of cell shape (12.4%) cell division (12.4%) peptidoglycan biosynthetic process (12.3%)" cytoplasm (12.4%) "ATP binding (12.5%) magnesium ion binding (12.3%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.3%)" "IPR036615 (14.3%) IPR004101 (14.2%) IPR013221 (14.1%)" "Mur ligase, C-terminal domain superfamily (14.3%) Mur ligase, C-terminal (14.2%) Mur ligase, central (14.1%)" SFDQLDNAPEEKER root 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (15.2%) GO:0032045 (12.2%)" "GO:0003746 (15.2%) GO:0003924 (15.2%) GO:0005525 (15.2%)" "cytosol (15.2%) guanyl-nucleotide exchange factor complex (12.2%)" "translation elongation factor activity (15.2%) GTPase activity (15.2%) GTP binding (15.2%)" "IPR000795 (8.4%) IPR031157 (8.4%) IPR050055 (8.4%)" "Translational (tr)-type GTP-binding domain (8.4%) Tr-type G domain, conserved site (8.4%) Elongation factor Tu GTPase (8.4%)" HSAMFSLGYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VYEGNDLKVDNAGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.6%) IPR019533 (25.6%) IPR019758 (25.6%)" "Peptidase S26A, signal peptidase I (25.6%) Peptidase S26 (25.6%) Peptidase S26A, signal peptidase I, conserved site (25.6%)" GLLPFCQDTGTALLHGEK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (22.7%) "GO:0046872 (23%) GO:0051539 (23%) GO:0004333 (21.8%)" tricarboxylic acid cycle (22.7%) "metal ion binding (23%) 4 iron, 4 sulfur cluster binding (23%) fumarate hydratase activity (21.8%)" "IPR004646 (18.6%) IPR051208 (18.6%) IPR004647 (18.3%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.6%) Class-I Fumarase/Tartrate Dehydratase (18.6%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.3%)" KELEGDMGDNVVGLQAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006281 (13%) GO:0006310 (13%) GO:0009432 (11.7%)" GO:0005829 (13%) "GO:0003697 (13%) GO:0005524 (13%) GO:0140664 (13%)" "DNA repair (13%) DNA recombination (13%) SOS response (11.7%)" cytosol (13%) "single-stranded DNA binding (13%) ATP binding (13%) ATP-dependent DNA damage sensor activity (13%)" "IPR013765 (11.8%) IPR020584 (11.8%) IPR020587 (11.8%)" "DNA recombination and repair protein RecA (11.8%) DNA recombination/repair protein RecA, conserved site (11.8%) DNA recombination and repair protein RecA, monomer-monomer interface (11.8%)" DGENGFPGNVTATAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.1.3.3 (96.8%) 5.1.3.- (3.2%)" "aldose 1-epimerase (96.8%) Acting on carbohydrates and derivatives (3.2%)" "GO:0006006 (20.3%) GO:0033499 (20.3%)" GO:0005737 (20.3%) "GO:0004034 (20.3%) GO:0030246 (19%)" "glucose metabolic process (20.3%) galactose catabolic process via UDP-galactose, Leloir pathway (20.3%)" cytoplasm (20.3%) "aldose 1-epimerase activity (20.3%) carbohydrate binding (19%)" "IPR008183 (17.2%) IPR018052 (17.2%) IPR047215 (17.2%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.2%) Aldose 1-epimerase, conserved site (17.2%) Galactose mutarotase-like (17.2%)" TFGAVPLLHNNTDLLGAGTYNDQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.9%) IPR033985 (33.9%) IPR012944 (32.1%)" "Tetratricopeptide-like helical domain superfamily (33.9%) SusD-like, N-terminal (33.9%) RagB/SusD domain (32.1%)" YNLYLVDVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.5%) GO:0008360 (14%) GO:0009252 (14%)" GO:0005737 (14%) "GO:0005524 (14.5%) GO:0008716 (14.5%) GO:0046872 (14.5%)" "cell wall organization (14.5%) regulation of cell shape (14%) peptidoglycan biosynthetic process (14%)" cytoplasm (14%) "ATP binding (14.5%) D-alanine-D-alanine ligase activity (14.5%) metal ion binding (14.5%)" "IPR000291 (14.4%) IPR005905 (14.4%) IPR011095 (14.4%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.4%) D-alanine--D-alanine ligase (14.4%) D-alanine--D-alanine ligase, C-terminal (14.4%)" VAGLVVQNTAGGASGSTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006826 (8.9%) GO:0044718 (7.1%)" GO:0009279 (76.8%) GO:0015344 (7.1%) "iron ion transport (8.9%) siderophore transmembrane transport (7.1%)" cell outer membrane (76.8%) siderophore uptake transmembrane transporter activity (7.1%) "IPR012910 (14%) IPR023997 (14%) IPR039426 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%) TonB-dependent receptor-like (14%)" EEGFEELAAK Bacteria Bacteria 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0016491 (46.2%) GO:0016692 (3.8%)" "iron ion binding (50%) oxidoreductase activity (46.2%) NADH peroxidase activity (3.8%)" "IPR003251 (14.6%) IPR009040 (14.6%) IPR024934 (14.6%)" "Rubrerythrin, diiron-binding domain (14.6%) Ferritin-like diiron domain (14.6%) Rubredoxin-like domain (14.6%)" LLGDLTPEK root "6.3.5.2 (99.9%) 3.1.3.89 (0.1%)" "GMP synthase (glutamine-hydrolyzing) (99.9%) 5'-deoxynucleotidase (0.1%)" "GO:0006285 (0.1%) GO:0007034 (0.1%)" "GO:0005829 (33%) GO:0005737 (0.1%)" "GO:0003921 (33%) GO:0005524 (33%) GO:0008483 (0.3%)" "base-excision repair, AP site formation (0.1%) vacuolar transport (0.1%)" "cytosol (33%) cytoplasm (0.1%)" "GMP synthase activity (33%) ATP binding (33%) transaminase activity (0.3%)" "IPR001674 (12.6%) IPR025777 (12.6%) IPR014729 (12.6%)" "GMP synthase, C-terminal (12.6%) GMP synthetase ATP pyrophosphatase domain (12.6%) Rossmann-like alpha/beta/alpha sandwich fold (12.6%)" EQGSDALHDTVHEMAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (40.6%) GO:0016491 (9.4%)" "iron ion binding (50%) peroxidase activity (40.6%) oxidoreductase activity (9.4%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" YTLPSDVK root 5.3.1.25 (100%) L-fucose isomerase (100%) "GO:0006915 (8.7%) GO:0019571 (8.7%) GO:0042355 (8.7%)" "GO:0016020 (13%) GO:0005737 (8.7%) GO:0005763 (8.7%)" "GO:0003735 (8.7%) GO:0008736 (8.7%) GO:0008790 (8.7%)" "apoptotic process (8.7%) D-arabinose catabolic process (8.7%) L-fucose catabolic process (8.7%)" "membrane (13%) cytoplasm (8.7%) mitochondrial small ribosomal subunit (8.7%)" "structural constituent of ribosome (8.7%) L-fucose isomerase activity (8.7%) arabinose isomerase activity (8.7%)" "IPR004216 (5%) IPR005763 (5%) IPR008092 (5%)" "L-fucose/L-arabinose isomerase, C-terminal (5%) L-fucose isomerase (5%) Small ribosomal subunit protein mS29, metazoa (5%)" LLLEHLADGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR028082 (25.3%) IPR000843 (24.1%) IPR001761 (24.1%)" "Periplasmic binding protein-like I (25.3%) LacI-type HTH domain (24.1%) Periplasmic binding protein/LacI sugar binding domain (24.1%)" MAQFELTLLDWAEAHK Bacteria Bacteria "GO:0006004 (32.3%) GO:0005996 (1%)" GO:0005737 (33.3%) "GO:0008736 (32.3%) GO:0016861 (1%)" "fucose metabolic process (32.3%) monosaccharide metabolic process (1%)" cytoplasm (33.3%) "L-fucose isomerase activity (32.3%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" SSDHLLEAVESSEYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.- (100%) Dipeptidases (100%) GO:0006508 (50%) GO:0070573 (50%) proteolysis (50%) metallodipeptidase activity (50%) "IPR008257 (25.4%) IPR011697 (25.4%) IPR029062 (24.6%)" "Peptidase M19 (25.4%) Peptidase C26 (25.4%) Class I glutamine amidotransferase-like (24.6%)" AALPALFNPEDLNALEQALR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.3.1.108 (100%) caffeoyl-CoA reductase (100%) "GO:0009055 (97.2%) GO:0016491 (2.3%) GO:0003677 (0.3%)" "electron transfer activity (97.2%) oxidoreductase activity (2.3%) DNA binding (0.3%)" "IPR014729 (20.8%) IPR012255 (20.6%) IPR014730 (20.6%)" "Rossmann-like alpha/beta/alpha sandwich fold (20.8%) Electron transfer flavoprotein, beta subunit (20.6%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (20.6%)" LLGMGDVVSLVER root 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (19.3%) "GO:0048500 (19.3%) GO:0005886 (3.2%) GO:0005786 (0.1%)" "GO:0003924 (19.3%) GO:0005525 (19.3%) GO:0008312 (19.3%)" SRP-dependent cotranslational protein targeting to membrane (19.3%) "signal recognition particle (19.3%) plasma membrane (3.2%) signal recognition particle, endoplasmic reticulum targeting (0.1%)" "GTPase activity (19.3%) GTP binding (19.3%) 7S RNA binding (19.3%)" "IPR022941 (11.1%) IPR000897 (11.1%) IPR027417 (11.1%)" "Signal recognition particle, SRP54 subunit (11.1%) Signal recognition particle, SRP54 subunit, GTPase domain (11.1%) P-loop containing nucleoside triphosphate hydrolase (11.1%)" LDDNDKQLYGCTDPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" VTEGPQAYLSHVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071709 (48.1%) "GO:0009279 (42.9%) GO:0019867 (9.1%)" membrane assembly (48.1%) "cell outer membrane (42.9%) outer membrane (9.1%)" "IPR010827 (26.3%) IPR034746 (26.3%) IPR023707 (24.3%)" "POTRA domain, BamA/TamA-like (26.3%) POTRA domain (26.3%) Outer membrane protein assembly factor BamA (24.3%)" FLGTLNATNLFLGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (25%) "GO:0009279 (25%) GO:0046930 (25%)" GO:0015288 (25%) monoatomic ion transport (25%) "cell outer membrane (25%) pore complex (25%)" porin activity (25%) "IPR006664 (19.7%) IPR006665 (19.7%) IPR011250 (19.7%)" "Outer membrane protein, bacterial (19.7%) OmpA-like domain (19.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (19.7%)" VRDCQDQFLDAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17.8%) GO:0045259 (17.8%)" "GO:0005524 (17.8%) GO:0043531 (17.8%) GO:0046933 (17.8%)" "plasma membrane (17.8%) proton-transporting ATP synthase complex (17.8%)" "ATP binding (17.8%) ADP binding (17.8%) proton-transporting ATP synthase activity, rotational mechanism (17.8%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" ASLMLDDSPALPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.21 (50%) 3.2.1.37 (50%)" "beta-glucosidase (50%) xylan 1,4-beta-xylosidase (50%)" "GO:0031222 (24.9%) GO:0045493 (24.9%)" "GO:0009044 (24.9%) GO:0046556 (24.9%) GO:0008422 (0.5%)" "arabinan catabolic process (24.9%) xylan catabolic process (24.9%)" "xylan 1,4-beta-xylosidase activity (24.9%) alpha-L-arabinofuranosidase activity (24.9%) beta-glucosidase activity (0.5%)" "IPR001764 (9.5%) IPR044993 (9.5%) IPR002772 (9.1%)" "Glycoside hydrolase, family 3, N-terminal (9.5%) Beta-D-xylosidase (9.5%) Glycoside hydrolase family 3 C-terminal domain (9.1%)" VGALLLPDLQSVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.5%) GO:0005886 (25.5%) "GO:0000286 (25.5%) GO:0000166 (23.6%)" L-alanine catabolic process (25.5%) plasma membrane (25.5%) "alanine dehydrogenase activity (25.5%) nucleotide binding (23.6%)" "IPR007698 (20%) IPR007886 (20%) IPR008141 (20%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20%) Alanine dehydrogenase (20%)" TEFTLYK root "2.4.2.- (66.7%) 2.7.8.6 (33.3%)" "Pentosyltransferases (66.7%) undecaprenyl-phosphate galactose phosphotransferase (33.3%)" "GO:0006886 (4.1%) GO:0006904 (4.1%) GO:0007032 (4.1%)" "GO:0016020 (9.5%) GO:0005768 (4.1%) GO:0030897 (4.1%)" "GO:0008270 (4.8%) GO:0030674 (4.1%) GO:2001070 (3.4%)" "intracellular protein transport (4.1%) vesicle docking involved in exocytosis (4.1%) endosome organization (4.1%)" "membrane (9.5%) endosome (4.1%) HOPS complex (4.1%)" "zinc ion binding (4.8%) protein-macromolecule adaptor activity (4.1%) starch binding (3.4%)" "IPR000547 (4.6%) IPR007810 (4.6%) IPR003362 (3.8%)" "Clathrin, heavy chain/VPS, 7-fold repeat (4.6%) Pep3/Vps18, beta-propeller domain (4.6%) Bacterial sugar transferase (3.8%)" GLSMFLYDKR Pseudomonadati Bacteria Pseudomonadati "1.3.99.- (50%) 1.3.8.1 (42.1%) 1.3.8.- (7.9%)" "With other acceptors (50%) short-chain acyl-CoA dehydrogenase (42.1%) With a flavin as acceptor (7.9%)" "GO:0050660 (50%) GO:0003995 (27.6%) GO:0016627 (19.7%)" "flavin adenine dinucleotide binding (50%) acyl-CoA dehydrogenase activity (27.6%) oxidoreductase activity, acting on the CH-CH group of donors (19.7%)" "IPR006091 (9.5%) IPR009075 (9.5%) IPR052166 (9.5%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (9.5%) Acyl-CoA dehydrogenase/oxidase, C-terminal (9.5%) Diverse substrate specificity acyl-CoA dehydrogenase (9.5%)" YEMEDLVLVDGHAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (17.1%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (17.1%)" "IPR003953 (14.3%) IPR011280 (14.3%) IPR015939 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%)" GLPFAAPPVGNLR root 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0006629 (1.8%) GO:0006590 (0.9%) GO:0042446 (0.9%)" "GO:0005576 (1.8%) GO:0005615 (0.9%)" "GO:0016787 (77%) GO:0052689 (8.8%) GO:0004104 (5.3%)" "lipid metabolic process (1.8%) thyroid hormone generation (0.9%) hormone biosynthetic process (0.9%)" "extracellular region (1.8%) extracellular space (0.9%)" "hydrolase activity (77%) carboxylic ester hydrolase activity (8.8%) cholinesterase activity (5.3%)" "IPR002018 (21.8%) IPR029058 (21.4%) IPR019826 (20%)" "Carboxylesterase, type B (21.8%) Alpha/Beta hydrolase fold (21.4%) Carboxylesterase type B, active site (20%)" LPGVVTTQVSGAPGADDATLNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" GTLEGDLAASDLTFYR Bacteria Bacteria GO:0006004 (33.3%) GO:0005737 (33.3%) GO:0008736 (33.3%) fucose metabolic process (33.3%) cytoplasm (33.3%) L-fucose isomerase activity (33.3%) "IPR015888 (51.4%) IPR009015 (48.6%)" "L-fucose isomerase, C-terminal (51.4%) L-fucose isomerase, N-terminal/central domain superfamily (48.6%)" STVPETLLGVPVAQDSYGKVESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" VEVVTPEENMGDVLGDLNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (20.2%) GO:0005737 (19.8%) "GO:0003746 (20.2%) GO:0005525 (20.2%) GO:0003924 (19.8%)" ribosome disassembly (20.2%) cytoplasm (19.8%) "translation elongation factor activity (20.2%) GTP binding (20.2%) GTPase activity (19.8%)" "IPR000640 (6.3%) IPR004161 (6.3%) IPR005517 (6.3%)" "Elongation factor EFG, domain V-like (6.3%) Translation elongation factor EFTu-like, domain 2 (6.3%) Translation elongation factor EFG/EF2, domain IV (6.3%)" LNHTPGWLFPVSYEVQNGETTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" VLSDYAVQGFPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0017004 (24%) GO:0030313 (22.1%) "GO:0016209 (26.9%) GO:0016491 (26.9%)" cytochrome complex assembly (24%) cell envelope (22.1%) "antioxidant activity (26.9%) oxidoreductase activity (26.9%)" "IPR000866 (20.3%) IPR013766 (20.3%) IPR025380 (20.3%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (20.3%) Thioredoxin domain (20.3%) Domain of unknown function DUF4369 (20.3%)" TFGVEVVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR032283 (35.9%) IPR038081 (33.3%) IPR032299 (30.8%)" "Domain of unknown function DUF4984 (35.9%) CalX-like domain superfamily (33.3%) Protein of unknown function DUF4843 (30.8%)" NTFYQFSPEFQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005524 (100%) ATP binding (100%) IPR029492 (100%) Domain of unknown function DUF4435 (100%) NTNTSLNFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.3%) IPR039426 (15.3%) IPR012910 (14.6%)" "TonB-dependent outer membrane protein, SusC/RagA (15.3%) TonB-dependent receptor-like (15.3%) TonB-dependent receptor, plug domain (14.6%)" VAGMTFEGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027385 (100%) Outer membrane protein, beta-barrel domain (100%) NFQGYVEELYNCLPDKEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" DMLTFGGSPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.2%) IPR027417 (25.2%) IPR050764 (25.2%)" "ATPase, AAA-3 (25.2%) P-loop containing nucleoside triphosphate hydrolase (25.2%) CbbQ/NirQ/NorQ/GpvN (25.2%)" AANSVSYYAQTAQVDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.9%) IPR033985 (33.9%) IPR011990 (32.1%)" "RagB/SusD domain (33.9%) SusD-like, N-terminal (33.9%) Tetratricopeptide-like helical domain superfamily (32.1%)" SGLLTAPLR root "3.6.4.- (81.1%) 3.6.4.12 (18.5%) 1.-.-.- (0.3%)" "Acting on ATP; involved in cellular and subcellular movement (81.1%) DNA helicase (18.5%) Oxidoreductases (0.3%)" "GO:0006281 (12.5%) GO:0006310 (12.5%) GO:0046168 (0.1%)" "GO:0005737 (12.4%) GO:0048476 (11.9%) GO:0016020 (0.1%)" "GO:0005524 (12.6%) GO:0009378 (12.5%) GO:0000400 (11.9%)" "DNA repair (12.5%) DNA recombination (12.5%) glycerol-3-phosphate catabolic process (0.1%)" "cytoplasm (12.4%) Holliday junction resolvase complex (11.9%) membrane (0.1%)" "ATP binding (12.6%) four-way junction helicase activity (12.5%) four-way junction DNA binding (11.9%)" "IPR027417 (12.5%) IPR004605 (12.5%) IPR008824 (12.5%)" "P-loop containing nucleoside triphosphate hydrolase (12.5%) Holliday junction branch migration complex subunit RuvB (12.5%) RuvB-like, AAA+ ATPase domain (12.5%)" STVSVLSPEVYAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001684 (53.3%) IPR018261 (46.7%)" "Large ribosomal subunit protein bL27 (53.3%) Large ribosomal subunit protein bL27, conserved site (46.7%)" TLNVPQGSSLMTTLNENGLFLPSACGGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16%) "GO:0005886 (16%) GO:0016020 (2.1%)" "GO:0009055 (16%) GO:0016655 (16%) GO:0046872 (16%)" sodium ion transport (16%) "plasma membrane (16%) membrane (2.1%)" "electron transfer activity (16%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16%) metal ion binding (16%)" "IPR001041 (10.9%) IPR012675 (10.9%) IPR036010 (10.9%)" "2Fe-2S ferredoxin-type iron-sulfur binding domain (10.9%) Beta-grasp domain superfamily (10.9%) 2Fe-2S ferredoxin-like superfamily (10.9%)" GTLASYSLDANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" GPAGSADLSGDEGESGFLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" QGGFTGGALNAVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" YEDVNGDGQLDTNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" SDEPSLLR root "2.7.1.2 (45.5%) 1.-.-.- (18.2%) 6.3.4.2 (18.2%)" "glucokinase (45.5%) Oxidoreductases (18.2%) CTP synthase (glutamine hydrolyzing) (18.2%)" "GO:0001503 (13.2%) GO:0045724 (13.2%) GO:0051216 (13.2%)" "GO:0005789 (13.9%) GO:0036064 (13.2%) GO:0005768 (1.4%)" "GO:0016301 (2.4%) GO:0004340 (1.7%) GO:0005085 (1.4%)" "ossification (13.2%) positive regulation of cilium assembly (13.2%) cartilage development (13.2%)" "endoplasmic reticulum membrane (13.9%) ciliary basal body (13.2%) endosome (1.4%)" "kinase activity (2.4%) glucokinase activity (1.7%) guanyl-nucleotide exchange factor activity (1.4%)" "IPR000600 (18.8%) IPR049874 (18.4%) IPR043129 (17.7%)" "ROK family (18.8%) ROK, conserved site (18.4%) ATPase, nucleotide binding domain (17.7%)" KLSTNVTDALVGSVPGLQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.3%) IPR023996 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" EVGNFTADEWYPGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0004130 (37%) GO:0009055 (31.5%) GO:0020037 (31.5%)" "cytochrome-c peroxidase activity (37%) electron transfer activity (31.5%) heme binding (31.5%)" "IPR010538 (35.1%) IPR051395 (35.1%) IPR036909 (29.8%)" "Di-haem oxidoreductase, putative peroxidase (35.1%) Cytochrome c-dependent Peroxidase and MauG (35.1%) Cytochrome c-like domain superfamily (29.8%)" LESGEADPSVYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR001387 (16.7%) IPR010982 (16.7%) IPR011051 (16.7%)" "Cro/C1-type, helix-turn-helix domain (16.7%) Lambda repressor-like, DNA-binding domain superfamily (16.7%) RmlC-like cupin domain superfamily (16.7%)" NLYPLSR root "2.7.13.3 (15.4%) 2.3.1.- (7.7%) 2.3.1.234 (7.7%)" "histidine kinase (15.4%) Transferring groups other than amino-acyl groups (7.7%) N(6)-L-threonylcarbamoyladenine synthase (7.7%)" "GO:0007032 (8.4%) GO:0032880 (8.4%) GO:0008610 (2.3%)" "GO:0005768 (8.4%) GO:0031083 (8.4%) GO:0016020 (4.2%)" "GO:0016746 (4%) GO:0016779 (3.8%) GO:0005524 (3.3%)" "endosome organization (8.4%) regulation of protein localization (8.4%) lipid biosynthetic process (2.3%)" "endosome (8.4%) BLOC-1 complex (8.4%) membrane (4.2%)" "acyltransferase activity (4%) nucleotidyltransferase activity (3.8%) ATP binding (3.3%)" "IPR051390 (5.6%) IPR019371 (5.5%) IPR008969 (2.5%)" "Biogenesis of lysosome-related organelles complex 1 subunit KXD1 (5.6%) KxDL domain (5.5%) Carboxypeptidase-like, regulatory domain superfamily (2.5%)" DGYLHGVDLPQLESFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25.2%) "GO:0004834 (25.2%) GO:0052684 (25.2%) GO:0030170 (24.3%)" cytoplasm (25.2%) "tryptophan synthase activity (25.2%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25.2%) pyridoxal phosphate binding (24.3%)" "IPR001926 (22%) IPR023026 (22%) IPR006316 (21.2%)" "Tryptophan synthase beta chain-like, PALP domain (22%) Tryptophan synthase beta chain/beta chain-like (22%) Tryptophan synthase, beta chain-like (21.2%)" LTSLAPLYTDKPNDQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.6%) IPR021120 (20.6%) IPR011051 (19.6%)" "5-keto 4-deoxyuronate isomerase (20.6%) KduI/IolB isomerase (20.6%) RmlC-like cupin domain superfamily (19.6%)" NLLGEMELDQTLTSR Bacteria Bacteria GO:0006508 (6.7%) "GO:0005886 (43.3%) GO:0098552 (43.3%)" GO:0008233 (6.7%) proteolysis (6.7%) "plasma membrane (43.3%) side of membrane (43.3%)" peptidase activity (6.7%) "IPR001107 (21.7%) IPR050710 (21.7%) IPR018080 (21.4%)" "Band 7 domain (21.7%) Band 7/mec-2 domain-containing protein (21.7%) Band 7/stomatin-like, conserved site (21.4%)" ELNEQLLADYLHSGAALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.3.2 (100%) UDP-glucose 4-epimerase (100%) GO:0006012 (33.3%) GO:0005829 (33.3%) GO:0003978 (33.3%) galactose metabolic process (33.3%) cytosol (33.3%) UDP-glucose 4-epimerase activity (33.3%) "IPR005886 (34.5%) IPR016040 (34.5%) IPR036291 (31%)" "UDP-glucose 4-epimerase (34.5%) NAD(P)-binding domain (34.5%) NAD(P)-binding domain superfamily (31%)" LPMTEKDVELVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0005975 (32%) GO:0006044 (32%)" "GO:0004342 (32%) GO:0016787 (1.9%) GO:0016853 (1.9%)" "carbohydrate metabolic process (32%) N-acetylglucosamine metabolic process (32%)" "glucosamine-6-phosphate deaminase activity (32%) hydrolase activity (1.9%) isomerase activity (1.9%)" "IPR052960 (18%) IPR024078 (17.5%) IPR003737 (17.1%)" "Glucosamine-6-phosphate deaminase-like (18%) Putative deacetylase LmbE-like domain superfamily (17.5%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (17.1%)" DVDAMLLR root "1.1.1.95 (45.5%) 2.5.1.17 (27.3%) 1.1.1.290 (18.2%)" "phosphoglycerate dehydrogenase (45.5%) corrinoid adenosyltransferase (27.3%) 4-phosphoerythronate dehydrogenase (18.2%)" "GO:0009236 (1.7%) GO:0006564 (1.2%) GO:0017000 (1.2%)" "GO:0005737 (2.9%) GO:0016020 (1.7%) GO:0005634 (0.6%)" "GO:0051287 (33.7%) GO:0016616 (29.7%) GO:0016757 (4.7%)" "cobalamin biosynthetic process (1.7%) L-serine biosynthetic process (1.2%) antibiotic biosynthetic process (1.2%)" "cytoplasm (2.9%) membrane (1.7%) nucleus (0.6%)" "NAD binding (33.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (29.7%) glycosyltransferase activity (4.7%)" "IPR006139 (22.5%) IPR006140 (22.5%) IPR036291 (22.5%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (22.5%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (22.5%) NAD(P)-binding domain superfamily (22.5%)" TFGGLDVALLGLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0005975 (33.3%) GO:0006044 (33.3%)" GO:0004342 (33.3%) "carbohydrate metabolic process (33.3%) N-acetylglucosamine metabolic process (33.3%)" glucosamine-6-phosphate deaminase activity (33.3%) "IPR004547 (17.3%) IPR006148 (17.3%) IPR052960 (17.3%)" "Glucosamine-6-phosphate isomerase (17.3%) Glucosamine/galactosamine-6-phosphate isomerase (17.3%) Glucosamine-6-phosphate deaminase-like (17.3%)" LNTLSQSPTATTAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (34%) IPR014358 (34%) IPR036291 (32.1%)" "Short-chain dehydrogenase/reductase SDR (34%) Enoyl-[acyl-carrier-protein] reductase (NADH) (34%) NAD(P)-binding domain superfamily (32.1%)" MLANNPALATR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009636 (23.5%) GO:0005886 (25.9%) "GO:0042910 (25.9%) GO:0015562 (24.7%)" response to toxic substance (23.5%) plasma membrane (25.9%) "xenobiotic transmembrane transporter activity (25.9%) efflux transmembrane transporter activity (24.7%)" "IPR001036 (34.4%) IPR004764 (32.8%) IPR027463 (32.8%)" "Acriflavin resistance protein (34.4%) Multidrug resistance protein MdtF-like (32.8%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (32.8%)" DLLGANPLALQLPLGAEENFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0032790 (20.1%) GO:0006412 (0.3%)" GO:0005737 (19.5%) "GO:0003924 (20.1%) GO:0005525 (20.1%) GO:0003746 (19.8%)" "ribosome disassembly (20.1%) translation (0.3%)" cytoplasm (19.5%) "GTPase activity (20.1%) GTP binding (20.1%) translation elongation factor activity (19.8%)" "IPR000795 (6.5%) IPR005225 (6.5%) IPR031157 (6.5%)" "Translational (tr)-type GTP-binding domain (6.5%) Small GTP-binding domain (6.5%) Tr-type G domain, conserved site (6.5%)" APTDNDFGAGLQK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.2%) GO:0009341 (25.2%) "GO:0004565 (25.2%) GO:0030246 (24.3%)" lactose catabolic process (25.2%) beta-galactosidase complex (25.2%) "beta-galactosidase activity (25.2%) carbohydrate binding (24.3%)" "IPR004199 (7.3%) IPR006102 (7.3%) IPR006103 (7.3%)" "Beta galactosidase small chain/ domain 5 (7.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.3%) Glycoside hydrolase family 2, catalytic domain (7.3%)" YGEAGLPDKTVNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (13.8%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (13.8%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" EMGLGLYPTGGETADVGDLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.4%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.4%)" "IPR004733 (20.1%) IPR016188 (20.1%) IPR036921 (20.1%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20.1%) PurM-like, N-terminal domain (20.1%) PurM-like, N-terminal domain superfamily (20.1%)" EGEALGTFYGFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (16%) GO:0009279 (84%) iron ion transport (16%) cell outer membrane (84%) "IPR000531 (13.1%) IPR039426 (13.1%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor-like (13.1%) TonB-dependent receptor, plug domain (12.5%)" QVLDLCTR root "GO:0005980 (27.7%) GO:0051301 (1.7%) GO:0051315 (0.8%)" "GO:0005634 (5%) GO:0016020 (1.7%) GO:0031262 (0.8%)" "GO:0004134 (27.7%) GO:0004135 (27.7%) GO:0003677 (2.5%)" "glycogen catabolic process (27.7%) cell division (1.7%) attachment of mitotic spindle microtubules to kinetochore (0.8%)" "nucleus (5%) membrane (1.7%) Ndc80 complex (0.8%)" "4-alpha-glucanotransferase activity (27.7%) amylo-alpha-1,6-glucosidase activity (27.7%) DNA binding (2.5%)" "IPR010401 (18.2%) IPR032790 (18.2%) IPR008928 (17.1%)" "Glycogen debranching enzyme (18.2%) Glycogen debranching enzyme, C-terminal (18.2%) Six-hairpin glycosidase superfamily (17.1%)" LTFPGNVDVTDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (28.9%) IPR014756 (28.9%) IPR040475 (28.9%)" "Immunoglobulin-like fold (28.9%) Immunoglobulin E-set (28.9%) Surface glycan-binding protein B, xyloglucan binding domain (28.9%)" DFVVAETAEEALK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.2%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.2%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" ATLLYAQGSNLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" SDFVYQAVLPSSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" LDGTDYVHAKPSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" LLHNFGSFEESNPVQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011467 (50%) IPR013783 (50%)" "Protein of unknown function DUF1573 (50%) Immunoglobulin-like fold (50%)" VGLLSNGTVTGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (34.7%) "GO:0004556 (32.7%) GO:0043169 (32.7%)" carbohydrate metabolic process (34.7%) "alpha-amylase activity (32.7%) cation binding (32.7%)" "IPR006047 (34.7%) IPR006046 (32.7%) IPR017853 (32.7%)" "Glycosyl hydrolase family 13, catalytic domain (34.7%) Alpha amylase (32.7%) Glycoside hydrolase superfamily (32.7%)" TATVQSLASGLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (33.3%) IPR027417 (33.3%) IPR050678 (33.3%)" "AAA domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) DNA Partitioning ATPase (33.3%)" FAGFFQSEEELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" WSVVESLPVVETLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.8 (100%) mannonate dehydratase (100%) GO:0042840 (25%) "GO:0008198 (25%) GO:0008927 (25%) GO:0030145 (25%)" D-glucuronate catabolic process (25%) "ferrous iron binding (25%) mannonate dehydratase activity (25%) manganese ion binding (25%)" "IPR004628 (50.8%) IPR036237 (49.2%)" "Mannonate dehydratase (50.8%) Xylose isomerase-like superfamily (49.2%)" NGETTSAPTDEDKQDLGSGLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (15.1%) IPR023996 (14.3%) IPR039426 (14.3%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (15.1%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent receptor-like (14.3%)" YTMWASYLGDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) ATLLNCDTYQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (25%) GO:0031564 (24.1%) GO:0006355 (0.9%)" GO:0005829 (25%) GO:0003723 (25%) "DNA-templated transcription termination (25%) transcription antitermination (24.1%) regulation of DNA-templated transcription (0.9%)" cytosol (25%) RNA binding (25%) "IPR006027 (33.7%) IPR011605 (33.7%) IPR035926 (32.5%)" "NusB/RsmB/TIM44 (33.7%) NusB antitermination factor (33.7%) NusB-like superfamily (32.5%)" NFEFVLK root "2.4.1.- (26.7%) 1.15.1.1 (13.3%) 2.3.2.23 (13.3%)" "Hexosyltransferases (26.7%) superoxide dismutase (13.3%) E2 ubiquitin-conjugating enzyme (13.3%)" "GO:0006164 (3.6%) GO:0055085 (2.8%) GO:0006024 (2.4%)" "GO:0005886 (8.5%) GO:0016020 (6.1%) GO:0005737 (4%)" "GO:0005524 (11.7%) GO:0016887 (10.1%) GO:0022857 (6.9%)" "purine nucleotide biosynthetic process (3.6%) transmembrane transport (2.8%) glycosaminoglycan biosynthetic process (2.4%)" "plasma membrane (8.5%) membrane (6.1%) cytoplasm (4%)" "ATP binding (11.7%) ATP hydrolysis activity (10.1%) transmembrane transporter activity (6.9%)" "IPR027417 (8.7%) IPR003439 (8%) IPR003593 (7.7%)" "P-loop containing nucleoside triphosphate hydrolase (8.7%) ABC transporter-like, ATP-binding domain (8%) AAA+ ATPase domain (7.7%)" NHYNEMEVNLNQAASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (51.4%) GO:0030246 (48.6%)" "hydrolase activity (51.4%) carbohydrate binding (48.6%)" "IPR019563 (15%) IPR029483 (15%) IPR029486 (15%)" "Glycosyl-hydrolase 97, catalytic domain (15%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (15%) Glycosyl-hydrolase 97, N-terminal domain (15%)" LDAWLEDLKPAL Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0010181 (52%) GO:0009055 (48%)" "FMN binding (52%) electron transfer activity (48%)" "IPR008254 (20.3%) IPR010086 (20.3%) IPR029039 (20.3%)" "Flavodoxin/nitric oxide synthase (20.3%) Flavodoxin, long chain (20.3%) Flavoprotein-like superfamily (20.3%)" KLNLDTDLDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.3%) IPR007644 (8.3%) IPR015712 (8.3%)" "RNA polymerase Rpb2, domain 2 (8.3%) RNA polymerase, beta subunit, protrusion (8.3%) DNA-directed RNA polymerase, subunit 2 (8.3%)" TCQLQMGVTELK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.3%) IPR021120 (20.3%) IPR011051 (19.8%)" "5-keto 4-deoxyuronate isomerase (20.3%) KduI/IolB isomerase (20.3%) RmlC-like cupin domain superfamily (19.8%)" EELAALAEVLK Bacteria Bacteria "2.6.1.- (96.4%) 2.6.1.1 (3.6%)" "Transaminases (96.4%) aspartate transaminase (3.6%)" GO:0006520 (28%) GO:0005737 (8.4%) "GO:0030170 (28%) GO:0008483 (20.6%) GO:0004069 (7.5%)" amino acid metabolic process (28%) cytoplasm (8.4%) "pyridoxal phosphate binding (28%) transaminase activity (20.6%) L-aspartate:2-oxoglutarate aminotransferase activity (7.5%)" "IPR004839 (17%) IPR015421 (17%) IPR015424 (17%)" "Aminotransferase, class I/classII, large domain (17%) Pyridoxal phosphate-dependent transferase, major domain (17%) Pyridoxal phosphate-dependent transferase (17%)" AGNLSDADLTDACEAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (34.8%) IPR034982 (34.8%) IPR038352 (30.4%)" "Imelysin-like domain (34.8%) Iron-regulated protein A, imelysin-like domain (34.8%) Imelysin-like domain superfamily (30.4%)" WNLNSLEFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.4.1.13 (50%) 1.4.1.14 (50%)" "glutamate synthase (NADPH) (50%) glutamate synthase (NADH) (50%)" GO:0006537 (32.7%) "GO:0016639 (32.7%) GO:0051536 (32.7%) GO:0004355 (0.9%)" glutamate biosynthetic process (32.7%) "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (32.7%) iron-sulfur cluster binding (32.7%) glutamate synthase (NADPH) activity (0.9%)" "IPR006005 (16.7%) IPR009051 (16.7%) IPR023753 (16.7%)" "Glutamate synthase, NADH/NADPH, small subunit 1 (16.7%) Alpha-helical ferredoxin (16.7%) FAD/NAD(P)-binding domain (16.7%)" DPSNSEKEAVNYLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.3%) IPR015712 (8.3%) IPR007644 (8.1%)" "RNA polymerase Rpb2, domain 2 (8.3%) DNA-directed RNA polymerase, subunit 2 (8.3%) RNA polymerase, beta subunit, protrusion (8.1%)" NNELYYMLNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" ANTLPGLFSTATLDEQTGEVLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.6%) IPR010720 (14.6%) IPR051563 (14.6%)" "Carbohydrate-binding, CenC-like (14.6%) Alpha-L-arabinofuranosidase, C-terminal (14.6%) Glycosyl Hydrolase Family 51 (14.6%)" EDLSAVAFTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (23.7%) GO:0006508 (3.2%)" GO:0005737 (22.6%) "GO:0005506 (22.6%) GO:0061711 (15.1%) GO:0016747 (8.6%)" "tRNA threonylcarbamoyladenosine modification (23.7%) proteolysis (3.2%)" cytoplasm (22.6%) "iron ion binding (22.6%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (15.1%) acyltransferase activity, transferring groups other than amino-acyl groups (8.6%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" FYTTNTPETNFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (31.6%) IPR012944 (31.6%) IPR033985 (29.1%)" "Tetratricopeptide-like helical domain superfamily (31.6%) RagB/SusD domain (31.6%) SusD-like, N-terminal (29.1%)" LDFSSVTWYGLPDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NGNDNLGDFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR039426 (13.3%) IPR012910 (12.7%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor-like (13.3%) TonB-dependent receptor, plug domain (12.7%)" TNTELVCQVPATAEVGTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" SDWELNLGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.20 (100%) diaminopimelate decarboxylase (100%) GO:0009089 (33.8%) "GO:0008836 (33.8%) GO:0030170 (32.4%)" lysine biosynthetic process via diaminopimelate (33.8%) "diaminopimelate decarboxylase activity (33.8%) pyridoxal phosphate binding (32.4%)" "IPR002986 (14.5%) IPR022643 (14.5%) IPR022644 (14.5%)" "Diaminopimelate decarboxylase, LysA (14.5%) Orn/DAP/Arg decarboxylase 2, C-terminal (14.5%) Orn/DAP/Arg decarboxylase 2, N-terminal (14.5%)" NVATANMPQVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.-.-.- (100%) Hydrolases (100%) "GO:0003676 (25%) GO:0004519 (25%) GO:0016787 (25%)" "nucleic acid binding (25%) endonuclease activity (25%) hydrolase activity (25%)" "IPR001604 (20.5%) IPR040255 (20.5%) IPR020821 (19.7%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (20.5%) Non-specific endonuclease (20.5%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (19.7%)" LPLDEFESR Bacteria Bacteria "GO:0006281 (14.3%) GO:0006310 (14.3%) GO:0051301 (14.3%)" "GO:0003677 (14.3%) GO:0003910 (14.3%) GO:0005524 (14.3%)" "DNA repair (14.3%) DNA recombination (14.3%) cell division (14.3%)" "DNA binding (14.3%) DNA ligase (ATP) activity (14.3%) ATP binding (14.3%)" "IPR025684 (42.1%) IPR026377 (42.1%) IPR000073 (1.3%)" "Gliding motility protein SprA N-terminal domain (42.1%) Cell surface SprA (42.1%) Alpha/beta hydrolase fold-1 (1.3%)" TKPHVNLGTLGHVDHGK root "3.6.5.3 (99.9%) 2.7.1.25 (0.1%) 1.10.2.2 (0%)" "protein-synthesizing GTPase (99.9%) adenylyl-sulfate kinase (0.1%) Transferred entry: 7.1.1.8 (0%)" "GO:0070125 (2.4%) GO:0006414 (0%) GO:0032790 (0%)" "GO:0005829 (14.9%) GO:0032045 (2.6%) GO:0005739 (2.4%)" "GO:0003746 (19.1%) GO:0003924 (19.1%) GO:0005525 (19.1%)" "mitochondrial translational elongation (2.4%) translational elongation (0%) ribosome disassembly (0%)" "cytosol (14.9%) guanyl-nucleotide exchange factor complex (2.6%) mitochondrion (2.4%)" "translation elongation factor activity (19.1%) GTPase activity (19.1%) GTP binding (19.1%)" "IPR027417 (8.7%) IPR000795 (8.7%) IPR050055 (8.5%)" "P-loop containing nucleoside triphosphate hydrolase (8.7%) Translational (tr)-type GTP-binding domain (8.7%) Elongation factor Tu GTPase (8.5%)" HNLDVLGGMEFSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YNLGFSHNDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (32.1%) GO:0009279 (67.9%) iron ion transport (32.1%) cell outer membrane (67.9%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FVDTKEEGVVLQYVTCEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" VREGEGDFGYNAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (16.9%) GO:0005737 (16.4%) "GO:0005524 (16.9%) GO:0140662 (16.9%) GO:0016853 (16.4%)" protein refolding (16.9%) cytoplasm (16.4%) "ATP binding (16.9%) ATP-dependent protein folding chaperone (16.9%) isomerase activity (16.4%)" "IPR001844 (17.1%) IPR002423 (17.1%) IPR018370 (17.1%)" "Chaperonin Cpn60/GroEL (17.1%) Chaperonin Cpn60/GroEL/TCP-1 family (17.1%) Chaperonin Cpn60, conserved site (17.1%)" FGTNTDLVTLVNEAHKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (26.5%) IPR017853 (25.2%) IPR045857 (25.2%)" "Glycosyl hydrolase family 13, catalytic domain (26.5%) Glycoside hydrolase superfamily (25.2%) Oligo-1,6-glucosidase, domain 2 (25.2%)" VEDLNWEVFR root 4.1.99.17 (100%) phosphomethylpyrimidine synthase (100%) "GO:0009228 (17%) GO:0009229 (16%)" GO:0005829 (16%) "GO:0051539 (17%) GO:0008270 (16%) GO:0016830 (8.5%)" "thiamine biosynthetic process (17%) thiamine diphosphate biosynthetic process (16%)" cytosol (16%) "4 iron, 4 sulfur cluster binding (17%) zinc ion binding (16%) carbon-carbon lyase activity (8.5%)" "IPR002817 (25%) IPR025747 (25%) IPR037509 (25%)" "Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B (25%) ThiC-associated domain (25%) Phosphomethylpyrimidine synthase (25%)" FASYELVPSDLQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25.4%) "GO:0003746 (25.4%) GO:0005525 (25.4%) GO:0003924 (23.9%)" ribosome disassembly (25.4%) "translation elongation factor activity (25.4%) GTP binding (25.4%) GTPase activity (23.9%)" "IPR000640 (8.1%) IPR005517 (8.1%) IPR035649 (8.1%)" "Elongation factor EFG, domain V-like (8.1%) Translation elongation factor EFG/EF2, domain IV (8.1%) EFG, domain V (8.1%)" VLVGADKMNDEESLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (20%) GO:0005886 (20%) "GO:0003723 (20%) GO:0004521 (20%) GO:0016787 (20%)" mRNA catabolic process (20%) plasma membrane (20%) "RNA binding (20%) RNA endonuclease activity (20%) hydrolase activity (20%)" "IPR003607 (12.7%) IPR004087 (12.7%) IPR004088 (12.7%)" "HD/PDEase domain (12.7%) K Homology domain (12.7%) K Homology domain, type 1 (12.7%)" ACEFLDGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (16.8%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.1%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (16.8%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.1%)" "IPR000722 (9.1%) IPR006592 (9.1%) IPR007066 (9.1%)" "RNA polymerase, alpha subunit (9.1%) RNA polymerase, N-terminal (9.1%) RNA polymerase Rpb1, domain 3 (9.1%)" FLPNVLGFLGGLDEPTPVPQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006354 (20.9%) GO:0031564 (20.9%) GO:0006353 (18.6%)" GO:0005829 (20.9%) "DNA-templated transcription elongation (20.9%) transcription antitermination (20.9%) DNA-templated transcription termination (18.6%)" cytosol (20.9%) "IPR006645 (13.2%) IPR036735 (13.2%) IPR043425 (13.2%)" "NusG-like, N-terminal (13.2%) NusG, N-terminal domain superfamily (13.2%) NusG-like (13.2%)" ENSEPWTANVNTR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" WDPFNAVLVSQYAGTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" AKLEVEANAFSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25.2%) GO:0022625 (25.2%) "GO:0003735 (25.2%) GO:0019843 (24.3%)" translation (25.2%) cytosolic large ribosomal subunit (25.2%) "structural constituent of ribosome (25.2%) rRNA binding (24.3%)" "IPR001196 (20.1%) IPR005749 (20.1%) IPR021131 (20.1%)" "Large ribosomal subunit protein uL15, conserved site (20.1%) Large ribosomal subunit protein uL15, bacteria (20.1%) Large ribosomal subunit protein uL15/eL18 (20.1%)" VPDVDALNALHQSELDALNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (3.7%) GO:0016020 (92.6%) GO:0008233 (3.7%) proteolysis (3.7%) membrane (92.6%) peptidase activity (3.7%) "IPR006665 (27.2%) IPR050330 (27.2%) IPR036737 (25%)" "OmpA-like domain (27.2%) Bacterial Outer Membrane Structural/Functional (27.2%) OmpA-like domain superfamily (25%)" FLSFFLK root "5.5.1.4 (12.9%) 6.1.1.19 (9.7%) 2.4.1.144 (8.1%)" "inositol-3-phosphate synthase (12.9%) arginine--tRNA ligase (9.7%) beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase (8.1%)" "GO:0008654 (5.6%) GO:0006021 (5.6%) GO:0006629 (0.5%)" "GO:0016020 (24%) GO:0005886 (5.3%) GO:0005634 (1.5%)" "GO:0004512 (5.6%) GO:0022857 (2.9%) GO:0005524 (2.5%)" "phospholipid biosynthetic process (5.6%) inositol biosynthetic process (5.6%) lipid metabolic process (0.5%)" "membrane (24%) plasma membrane (5.3%) nucleus (1.5%)" "inositol-3-phosphate synthase activity (5.6%) transmembrane transporter activity (2.9%) ATP binding (2.5%)" "IPR036291 (6.3%) IPR002587 (6.1%) IPR013021 (6.1%)" "NAD(P)-binding domain superfamily (6.3%) Myo-inositol-1-phosphate synthase (6.1%) Myo-inositol-1-phosphate synthase, GAPDH-like (6.1%)" NLDTENGNSVYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.3%) GO:0005737 (48.3%)" GO:0016787 (3.4%) "extracellular region (48.3%) cytoplasm (48.3%)" hydrolase activity (3.4%) "IPR006530 (14.9%) IPR022045 (14.9%) IPR050708 (14.9%)" "YD repeat (14.9%) Insecticide toxin TcdB middle/N-terminal (14.9%) Type VI secretion system VgrG/RHS (14.9%)" VSLSENTTGHLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR024361 (50%)" "Immunoglobulin-like fold (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" YLYGVCQEMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (20.3%) GO:0005829 (20.3%) "GO:0004335 (20.3%) GO:0005524 (20.3%) GO:0046872 (18.7%)" galactose metabolic process (20.3%) cytosol (20.3%) "galactokinase activity (20.3%) ATP binding (20.3%) metal ion binding (18.7%)" "IPR000705 (10.8%) IPR006203 (10.3%) IPR006204 (10.3%)" "Galactokinase (10.8%) GHMP kinase, ATP-binding, conserved site (10.3%) GHMP kinase N-terminal domain (10.3%)" VAPNHFLLVPGVGAQGGSLQEVCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.23 (100%) orotidine-5'-phosphate decarboxylase (100%) "GO:0006207 (33.3%) GO:0044205 (31.6%) GO:0009220 (1.8%)" GO:0004590 (33.3%) "'de novo' pyrimidine nucleobase biosynthetic process (33.3%) 'de novo' UMP biosynthetic process (31.6%) pyrimidine ribonucleotide biosynthetic process (1.8%)" orotidine-5'-phosphate decarboxylase activity (33.3%) "IPR001754 (25.7%) IPR011995 (25.7%) IPR011060 (24.3%)" "Orotidine 5'-phosphate decarboxylase domain (25.7%) Orotidine 5'-phosphate decarboxylase, type 2 (25.7%) Ribulose-phosphate binding barrel (24.3%)" NLGVATTPQLTELYQNYVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.7%) IPR002772 (12.7%) IPR026891 (12.7%)" "Glycoside hydrolase, family 3, N-terminal (12.7%) Glycoside hydrolase family 3 C-terminal domain (12.7%) Fibronectin type III-like domain (12.7%)" LPDNAVCAHANQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0016805 (33.3%) GO:0070004 (33.3%)" proteolysis (33.3%) "dipeptidase activity (33.3%) cysteine-type exopeptidase activity (33.3%)" IPR005322 (100%) Peptidase C69 (100%) VLGQVPGESNVEVMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (52.9%) IPR038377 (47.1%)" "Sodium/solute symporter (52.9%) Sodium/glucose symporter superfamily (47.1%)" SKNEVLAELVALLQSPAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (0.9%) "GO:0005840 (49.5%) GO:1990904 (48.6%)" GO:0070180 (0.9%) translation (0.9%) "ribosome (49.5%) ribonucleoprotein complex (48.6%)" large ribosomal subunit rRNA binding (0.9%) "IPR001790 (33.3%) IPR047865 (33.3%) IPR043141 (32.7%)" "Large ribosomal subunit protein uL10 (33.3%) Large ribosomal subunit protein uL10, bacteria/organella (33.3%) Large ribosomal subunit protein uL10-like domain superfamily (32.7%)" VGSNLASELGTMR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0015914 (0.1%) "GO:0043190 (49.9%) GO:0005886 (0.1%)" GO:0005548 (49.9%) phospholipid transport (0.1%) "ATP-binding cassette (ABC) transporter complex (49.9%) plasma membrane (0.1%)" phospholipid transporter activity (49.9%) IPR030802 (100%) ABC transporter permease MalE (100%) DLDWNVTAR Pseudomonadati Bacteria Pseudomonadati "IPR002881 (45.2%) IPR036465 (42.4%) IPR002035 (12.4%)" "Domain of unknown function DUF58 (45.2%) von Willebrand factor A-like domain superfamily (42.4%) von Willebrand factor, type A (12.4%)" LVAMNSVPLAWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001296 (34.3%) IPR028098 (34.3%) IPR050194 (31.4%)" "Glycosyl transferase, family 1 (34.3%) Glycosyltransferase subfamily 4-like, N-terminal domain (34.3%) Glycosyltransferase group 1 (31.4%)" GNSELTTEMDHQEALKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (92.3%) GO:0016740 (7.7%)" "glycosyltransferase activity (92.3%) transferase activity (7.7%)" "IPR000836 (51.5%) IPR029057 (48.5%)" "Phosphoribosyltransferase domain (51.5%) Phosphoribosyltransferase-like (48.5%)" LAETYNLGGFNEWK Pseudomonadati Bacteria Pseudomonadati 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (50%) GO:0008460 (50%) nucleotide-sugar metabolic process (50%) dTDP-glucose 4,6-dehydratase activity (50%) "IPR036291 (33.9%) IPR005888 (31.9%) IPR001509 (22.6%)" "NAD(P)-binding domain superfamily (33.9%) dTDP-glucose 4,6-dehydratase (31.9%) NAD-dependent epimerase/dehydratase (22.6%)" SFLVSTPNVDHPLQLEHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0042777 (19.8%) "GO:0005886 (19.8%) GO:0045259 (19.8%)" "GO:0005524 (19.8%) GO:0046933 (19.8%) GO:0016787 (0.9%)" proton motive force-driven plasma membrane ATP synthesis (19.8%) "plasma membrane (19.8%) proton-transporting ATP synthase complex (19.8%)" "ATP binding (19.8%) proton-transporting ATP synthase activity, rotational mechanism (19.8%) hydrolase activity (0.9%)" "IPR000131 (51.1%) IPR035968 (48.9%)" "ATP synthase, F1 complex, gamma subunit (51.1%) ATP synthase, F1 complex, gamma subunit superfamily (48.9%)" LELSVPLGK root 3.1.1.4 (100%) phospholipase A2 (100%) "GO:0008643 (26.4%) GO:0046475 (0.8%)" "GO:0016020 (26.4%) GO:0009279 (3.9%) GO:1990281 (3.9%)" "GO:0015288 (30.2%) GO:0015562 (3.9%) GO:0005509 (0.8%)" "carbohydrate transport (26.4%) glycerophospholipid catabolic process (0.8%)" "membrane (26.4%) cell outer membrane (3.9%) efflux pump complex (3.9%)" "porin activity (30.2%) efflux transmembrane transporter activity (3.9%) calcium ion binding (0.8%)" "IPR007049 (41%) IPR038673 (39.8%) IPR003423 (6%)" "Carbohydrate-selective porin OprB (41%) Carbohydrate-selective porin OprB superfamily (39.8%) Outer membrane efflux protein (6%)" FVFGSSTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" RLEMAMENGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.9%) IPR011990 (33.1%) IPR033985 (33.1%)" "RagB/SusD domain (33.9%) Tetratricopeptide-like helical domain superfamily (33.1%) SusD-like, N-terminal (33.1%)" LTGQLNQLSVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LLGEYELSTAANSYATAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" LDQFMDLLDKAPEEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.97.1.12 (100%) photosystem I (100%) GO:0016020 (95.2%) GO:0016491 (4.8%) membrane (95.2%) oxidoreductase activity (4.8%) "IPR006665 (33.9%) IPR050330 (33.9%) IPR036737 (32.2%)" "OmpA-like domain (33.9%) Bacterial Outer Membrane Structural/Functional (33.9%) OmpA-like domain superfamily (32.2%)" TFSVDSVVYSEEFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.- (40%) 2.1.1.173 (40%) 2.1.1.72 (20%)" "Methyltransferases (40%) 23S rRNA (guanine(2445)-N(2))-methyltransferase (40%) site-specific DNA-methyltransferase (adenine-specific) (20%)" "GO:0003723 (33.2%) GO:0070043 (33.2%) GO:0008990 (32.8%)" "RNA binding (33.2%) rRNA (guanine-N7-)-methyltransferase activity (33.2%) rRNA (guanine-N2-)-methyltransferase activity (32.8%)" "IPR000241 (17.5%) IPR004114 (17.5%) IPR054170 (17.5%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.5%) THUMP domain (17.5%) RlmL, ferredoxin-like domain (17.5%)" NGQDLLYYVQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) ESTFGKDLEFQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.1%) IPR028053 (17.1%) IPR028055 (17.1%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.1%) Membrane insertase YidC, N-terminal (17.1%) Membrane insertase YidC/Oxa/ALB, C-terminal (17.1%)" YLLQNSEWWLESAGLDGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" DKYVSTSELNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (16.7%) "GO:0005737 (16.7%) GO:0005886 (16.7%)" "GO:0003924 (16.7%) GO:0005047 (16.7%) GO:0005525 (16.7%)" SRP-dependent cotranslational protein targeting to membrane (16.7%) "cytoplasm (16.7%) plasma membrane (16.7%)" "GTPase activity (16.7%) signal recognition particle binding (16.7%) GTP binding (16.7%)" "IPR000897 (14.3%) IPR003593 (14.3%) IPR004390 (14.3%)" "Signal recognition particle, SRP54 subunit, GTPase domain (14.3%) AAA+ ATPase domain (14.3%) Signal-recognition particle receptor FtsY (14.3%)" LTYTLSR root "5.6.2.4 (63.6%) 3.6.4.- (7.6%) 3.2.1.- (4.5%)" "DNA 3'-5' helicase (63.6%) Acting on ATP; involved in cellular and subcellular movement (7.6%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (4.5%)" "GO:0000725 (5.4%) GO:0030497 (2.6%) GO:0007156 (0.9%)" "GO:0016020 (7.4%) GO:0005829 (5.8%) GO:0033202 (5.4%)" "GO:0003677 (6.8%) GO:0005524 (6.1%) GO:0043138 (5.4%)" "recombinational repair (5.4%) fatty acid elongation (2.6%) homophilic cell-cell adhesion (0.9%)" "membrane (7.4%) cytosol (5.8%) DNA helicase complex (5.4%)" "DNA binding (6.8%) ATP binding (6.1%) 3'-5' DNA helicase activity (5.4%)" "IPR027417 (5%) IPR000212 (4.4%) IPR013986 (4.4%)" "P-loop containing nucleoside triphosphate hydrolase (5%) DNA helicase, UvrD/REP type (4.4%) DExx box DNA helicase domain superfamily (4.4%)" YGNVPFLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (50.3%) IPR042278 (49.7%)" "Fimbrillin-like 1 (50.3%) Fimbrillin-like 1, N-terminal (49.7%)" AYHLQADYTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" DVVLESAYFHPTWLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002547 (7.9%) IPR004532 (7.9%) IPR005121 (7.9%)" "tRNA-binding domain (7.9%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.9%) Ferrodoxin-fold anticodon-binding domain (7.9%)" KADTELPAYNVTLDYMSGGLDMAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" VYHLNLGQPDLPTPQCGLDALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.6.1.- (50%) 2.6.1.1 (50%)" "Transaminases (50%) aspartate transaminase (50%)" GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (28.9%) GO:0004069 (4.4%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (28.9%) L-aspartate:2-oxoglutarate aminotransferase activity (4.4%)" "IPR004839 (20.5%) IPR050596 (20.5%) IPR015421 (19.6%)" "Aminotransferase, class I/classII, large domain (20.5%) Aspartate/prephenate aminotransferase-like (20.5%) Pyridoxal phosphate-dependent transferase, major domain (19.6%)" DHGMQNLLEGQLDPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.10 (100%) orotate phosphoribosyltransferase (100%) "GO:0019856 (25%) GO:0044205 (25%)" "GO:0000287 (25%) GO:0004588 (25%)" "pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" "magnesium ion binding (25%) orotate phosphoribosyltransferase activity (25%)" "IPR000836 (25%) IPR004467 (25%) IPR023031 (25%)" "Phosphoribosyltransferase domain (25%) Orotate phosphoribosyl transferase domain (25%) Orotate phosphoribosyltransferase (25%)" SFFAVAESPNGVDNFR Pseudomonadati Bacteria Pseudomonadati 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (26.6%) GO:0071555 (26.6%)" "GO:0016758 (26.6%) GO:0016798 (16.2%) GO:0016787 (2.6%)" "carbohydrate metabolic process (26.6%) cell wall organization (26.6%)" "hexosyltransferase activity (26.6%) hydrolase activity, acting on glycosyl bonds (16.2%) hydrolase activity (2.6%)" "IPR007184 (33.3%) IPR028583 (33.3%) IPR023296 (32.9%)" "Mannoside phosphorylase (33.3%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (33.3%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.9%)" VLSVLAGR root "1.5.1.2 (37%) 1.4.1.13 (31.5%) 2.7.13.3 (4.1%)" "pyrroline-5-carboxylate reductase (37%) glutamate synthase (NADPH) (31.5%) histidine kinase (4.1%)" "GO:0055129 (3.8%) GO:0006511 (0.8%) GO:0006355 (0.7%)" "GO:0005737 (4.7%) GO:0016020 (4.7%) GO:0005886 (3.6%)" "GO:0051536 (20.3%) GO:0016491 (17.2%) GO:0004355 (3.8%)" "L-proline biosynthetic process (3.8%) ubiquitin-dependent protein catabolic process (0.8%) regulation of DNA-templated transcription (0.7%)" "cytoplasm (4.7%) membrane (4.7%) plasma membrane (3.6%)" "iron-sulfur cluster binding (20.3%) oxidoreductase activity (17.2%) glutamate synthase (NADPH) activity (3.8%)" "IPR036188 (7.6%) IPR017927 (7.4%) IPR019480 (7.4%)" "FAD/NAD(P)-binding domain superfamily (7.6%) FAD-binding domain, ferredoxin reductase-type (7.4%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (7.4%)" WLDTDLLSYDNNSTSYGSGTTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" LVVFLNK root "3.6.5.3 (96.8%) 2.3.2.26 (1.9%) 2.7.1.25 (0.7%)" "protein-synthesizing GTPase (96.8%) HECT-type E3 ubiquitin transferase (1.9%) adenylyl-sulfate kinase (0.7%)" "GO:0070125 (5.1%) GO:0016567 (0.2%) GO:0006511 (0.2%)" "GO:0005829 (11.3%) GO:0005739 (5.2%) GO:0032045 (4.9%)" "GO:0003746 (17.2%) GO:0005525 (17.2%) GO:0003924 (17.2%)" "mitochondrial translational elongation (5.1%) protein ubiquitination (0.2%) ubiquitin-dependent protein catabolic process (0.2%)" "cytosol (11.3%) mitochondrion (5.2%) guanyl-nucleotide exchange factor complex (4.9%)" "translation elongation factor activity (17.2%) GTP binding (17.2%) GTPase activity (17.2%)" "IPR000795 (9.5%) IPR050055 (9.5%) IPR027417 (9.4%)" "Translational (tr)-type GTP-binding domain (9.5%) Elongation factor Tu GTPase (9.5%) P-loop containing nucleoside triphosphate hydrolase (9.4%)" NKYTYFASK Bacteria Bacteria "1.11.1.1 (76.9%) 1.14.13.81 (23.1%)" "NADH peroxidase (76.9%) magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (23.1%)" GO:0006418 (0.3%) "GO:0016491 (47%) GO:0005506 (43.8%) GO:0046872 (5.4%)" tRNA aminoacylation for protein translation (0.3%) "oxidoreductase activity (47%) iron ion binding (43.8%) metal ion binding (5.4%)" "IPR003251 (14.5%) IPR009040 (14.5%) IPR052364 (14.5%)" "Rubrerythrin, diiron-binding domain (14.5%) Ferritin-like diiron domain (14.5%) Rubrerythrin (14.5%)" QEGMWNTEGTEMNDGYSTQHVLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" FSDLGGLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005765 (45.6%) GO:0012505 (2.9%) GO:0016020 (2.9%)" GO:0022857 (48.5%) "lysosomal membrane (45.6%) endomembrane system (2.9%) membrane (2.9%)" transmembrane transporter activity (48.5%) "IPR011701 (25.4%) IPR020846 (25.4%) IPR052187 (25.4%)" "Major facilitator superfamily (25.4%) Major facilitator superfamily domain (25.4%) Lysosomal dipeptide transporter MFSD1 (25.4%)" RLELAFEGER root GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR011990 (33.3%) IPR033985 (32.7%)" "RagB/SusD domain (34%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (32.7%)" SYTNEHGESLQPNAKPGDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VLNADVVVLTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" YGLPEFR root "1.4.1.13 (85.6%) 1.4.1.14 (5%) 1.8.1.19 (1.9%)" "glutamate synthase (NADPH) (85.6%) glutamate synthase (NADH) (5%) sulfide dehydrogenase (1.9%)" "GO:0006261 (0.1%) GO:0006383 (0.1%) GO:0019290 (0%)" "GO:0016020 (0.2%) GO:0005737 (0.2%) GO:0000127 (0.1%)" "GO:0051536 (47.9%) GO:0016491 (34.3%) GO:0004355 (13.7%)" "DNA-templated DNA replication (0.1%) transcription by RNA polymerase III (0.1%) siderophore biosynthetic process (0%)" "membrane (0.2%) cytoplasm (0.2%) transcription factor TFIIIC complex (0.1%)" "iron-sulfur cluster binding (47.9%) oxidoreductase activity (34.3%) glutamate synthase (NADPH) activity (13.7%)" "IPR036188 (17.1%) IPR023753 (16.9%) IPR028261 (16.8%)" "FAD/NAD(P)-binding domain superfamily (17.1%) FAD/NAD(P)-binding domain (16.9%) Dihydroprymidine dehydrogenase domain II (16.8%)" SQTQDDFLMER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "5.6.2.4 (92.6%) 3.6.4.12 (7.4%)" "DNA 3'-5' helicase (92.6%) DNA helicase (7.4%)" "GO:0006260 (8.3%) GO:0006281 (8.3%) GO:0006310 (8.3%)" "GO:0005737 (8.3%) GO:0030894 (8.3%) GO:0043590 (8.3%)" "GO:0005524 (8.3%) GO:0009378 (8.3%) GO:0016787 (8.3%)" "DNA replication (8.3%) DNA repair (8.3%) DNA recombination (8.3%)" "cytoplasm (8.3%) replisome (8.3%) bacterial nucleoid (8.3%)" "ATP binding (8.3%) four-way junction helicase activity (8.3%) hydrolase activity (8.3%)" "IPR001650 (7.2%) IPR002121 (7.2%) IPR004589 (7.2%)" "Helicase, C-terminal domain-like (7.2%) HRDC domain (7.2%) DNA helicase, ATP-dependent, RecQ type (7.2%)" LFLETFVK root "GO:0000028 (14%) GO:0000160 (0.1%) GO:0006355 (0.1%)" "GO:0005829 (13.9%) GO:0005886 (13.7%) GO:0005737 (0.3%)" "GO:0005525 (14%) GO:0043024 (14%) GO:0003924 (13.6%)" "ribosomal small subunit assembly (14%) phosphorelay signal transduction system (0.1%) regulation of DNA-templated transcription (0.1%)" "cytosol (13.9%) plasma membrane (13.7%) cytoplasm (0.3%)" "GTP binding (14%) ribosomal small subunit binding (14%) GTPase activity (13.6%)" "IPR004044 (12.1%) IPR005662 (12.1%) IPR005225 (12%)" "K Homology domain, type 2 (12.1%) GTPase Era-like (12.1%) Small GTP-binding domain (12%)" LSWDTFR root "2.4.99.16 (50%) 2.7.7.12 (50%)" "starch synthase (maltosyl-transferring) (50%) UDP-glucose--hexose-1-phosphate uridylyltransferase (50%)" "GO:0006884 (0.9%) GO:0034486 (0.9%) GO:0055064 (0.9%)" "GO:0005737 (45.8%) GO:0005774 (0.9%) GO:0005634 (0.1%)" "GO:0016149 (45.2%) GO:0015379 (0.9%) GO:0016787 (0.9%)" "cell volume homeostasis (0.9%) vacuolar transmembrane transport (0.9%) chloride ion homeostasis (0.9%)" "cytoplasm (45.8%) vacuolar membrane (0.9%) nucleus (0.1%)" "translation release factor activity, codon specific (45.2%) potassium:chloride symporter activity (0.9%) hydrolase activity (0.9%)" "IPR000352 (24.1%) IPR005139 (24%) IPR045853 (24%)" "Peptide chain release factor class I (24.1%) Peptide chain release factor (24%) Peptide chain release factor class I superfamily (24%)" VLLNEDEATLPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.7%) GO:0016787 (48.3%) membrane (51.7%) hydrolase activity (48.3%) "IPR000560 (51.7%) IPR029033 (48.3%)" "Histidine phosphatase superfamily, clade-2 (51.7%) Histidine phosphatase superfamily (48.3%)" KQLNELTDFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0004815 (20%) GO:0005524 (20%) GO:0003676 (19.8%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "aspartate-tRNA ligase activity (20%) ATP binding (20%) nucleic acid binding (19.8%)" "IPR004364 (9.1%) IPR004524 (9.1%) IPR006195 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.1%) Aspartate-tRNA ligase, type 1 (9.1%) Aminoacyl-tRNA synthetase, class II (9.1%)" EMYGNTWTPDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (15.7%) IPR039426 (15.7%) IPR012910 (14.2%)" "TonB-dependent outer membrane protein, SusC/RagA (15.7%) TonB-dependent receptor-like (15.7%) TonB-dependent receptor, plug domain (14.2%)" VVSWYDNELGYSHK Pseudomonadati Bacteria Pseudomonadati 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0004365 (13.9%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (13.9%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" NGVDLLATPDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006813 (33.3%) "GO:0005886 (31.4%) GO:0016020 (2%)" GO:0008324 (33.3%) potassium ion transport (33.3%) "plasma membrane (31.4%) membrane (2%)" monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.8%) IPR050144 (25.8%) IPR006512 (24.2%)" "Regulator of K+ conductance, C-terminal (25.8%) AAE Transporter (25.8%) YidE/YbjL duplication (24.2%)" LLPVVGMK root GO:0009451 (1.3%) "GO:0016020 (96.2%) GO:0005739 (0.6%) GO:0005886 (0.6%)" GO:0003723 (1.3%) RNA modification (1.3%) "membrane (96.2%) mitochondrion (0.6%) plasma membrane (0.6%)" RNA binding (1.3%) "IPR002549 (86.9%) IPR007841 (7.3%) IPR002885 (1%)" "Transmembrane protein TqsA-like (86.9%) Uncharacterised protein family UPF0210 (7.3%) Pentatricopeptide repeat (1%)" LPHPLLTNTQLDLLQNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.4.1.13 (97.5%) 1.4.-.- (2.5%)" "glutamate synthase (NADPH) (97.5%) Acting on the CH-NH2 group of donors (2.5%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.1%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.1%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" TDLFVLR root "2.1.3.2 (71.3%) 5.1.3.3 (22.8%) 3.1.2.- (2%)" "aspartate carbamoyltransferase (71.3%) aldose 1-epimerase (22.8%) Thiolester hydrolases (2%)" "GO:0006207 (5.6%) GO:0006520 (5.6%) GO:0044205 (5.6%)" "GO:0005886 (38%) GO:0005829 (6%) GO:0016020 (2.9%)" "GO:0004070 (5.6%) GO:0016597 (5.6%) GO:0030246 (2.2%)" "'de novo' pyrimidine nucleobase biosynthetic process (5.6%) amino acid metabolic process (5.6%) 'de novo' UMP biosynthetic process (5.6%)" "plasma membrane (38%) cytosol (6%) membrane (2.9%)" "aspartate carbamoyltransferase activity (5.6%) amino acid binding (5.6%) carbohydrate binding (2.2%)" "IPR028994 (18.1%) IPR024881 (17.8%) IPR013517 (17.2%)" "Integrin alpha, N-terminal (18.1%) T-cell immunomodulatory protein (17.8%) FG-GAP repeat (17.2%)" LANYPFTTLEPSLGLVDYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (16.7%) GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" ribosome biogenesis (16.7%) cytoplasm (16.7%) "magnesium ion binding (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR006073 (12.5%) IPR006074 (12.5%) IPR006169 (12.5%)" "GTP binding domain (12.5%) GTP1/OBG, conserved site (12.5%) GTP1/OBG domain (12.5%)" YNFGEKPGPLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0008652 (13.4%) GO:0009082 (13.4%) GO:0009097 (11.9%)" "GO:0004084 (19.4%) GO:0052654 (6%) GO:0052655 (6%)" "amino acid biosynthetic process (13.4%) branched-chain amino acid biosynthetic process (13.4%) isoleucine biosynthetic process (11.9%)" "branched-chain-amino-acid transaminase activity (19.4%) L-leucine-2-oxoglutarate transaminase activity (6%) L-valine-2-oxoglutarate transaminase activity (6%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" LDLTPSTDVDALLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.10 (100%) phosphoglucosamine mutase (100%) "GO:0005975 (14.3%) GO:0006048 (14.3%) GO:0009252 (14.3%)" GO:0005829 (14.3%) "GO:0000287 (14.3%) GO:0004615 (14.3%) GO:0008966 (14.3%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.3%) peptidoglycan biosynthetic process (14.3%)" cytosol (14.3%) "magnesium ion binding (14.3%) phosphomannomutase activity (14.3%) phosphoglucosamine mutase activity (14.3%)" "IPR005843 (10.2%) IPR005844 (10.2%) IPR005845 (10.2%)" "Alpha-D-phosphohexomutase, C-terminal (10.2%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10.2%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (10.2%)" YLGSATATSADLPMSADEAVDKLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (37.1%) IPR012944 (37.1%) IPR033985 (25.7%)" "Tetratricopeptide-like helical domain superfamily (37.1%) RagB/SusD domain (37.1%) SusD-like, N-terminal (25.7%)" YLADGLTGSAYER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR012944 (34.4%) IPR033985 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) RagB/SusD domain (34.4%) SusD-like, N-terminal (31.3%)" VFDATYR root "1.-.-.- (33.3%) 2.4.-.- (33.3%) 3.1.21.3 (33.3%)" "Oxidoreductases (33.3%) Glycosyltransferases (33.3%) type I site-specific deoxyribonuclease (33.3%)" "GO:0006508 (12.4%) GO:0006355 (2%) GO:0008202 (1.2%)" "GO:0009279 (11.6%) GO:0005576 (10%) GO:0005634 (6.8%)" "GO:0004252 (12.4%) GO:0008270 (7.2%) GO:0046872 (6%)" "proteolysis (12.4%) regulation of DNA-templated transcription (2%) steroid metabolic process (1.2%)" "cell outer membrane (11.6%) extracellular region (10%) nucleus (6.8%)" "serine-type endopeptidase activity (12.4%) zinc ion binding (7.2%) metal ion binding (6%)" "IPR000209 (4.5%) IPR023828 (4.5%) IPR036852 (4.5%)" "Peptidase S8/S53 domain (4.5%) Peptidase S8, subtilisin, Ser-active site (4.5%) Peptidase S8/S53 domain superfamily (4.5%)" GGEVLTVCGAGGNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.2.13 (100%) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase (100%) "GO:0008360 (12.4%) GO:0009252 (12.4%) GO:0051301 (12.4%)" GO:0005737 (12.4%) "GO:0005524 (12.9%) GO:0000287 (12.4%) GO:0008765 (12.4%)" "regulation of cell shape (12.4%) peptidoglycan biosynthetic process (12.4%) cell division (12.4%)" cytoplasm (12.4%) "ATP binding (12.9%) magnesium ion binding (12.4%) UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity (12.4%)" "IPR004101 (14.6%) IPR013221 (14.6%) IPR036565 (14.6%)" "Mur ligase, C-terminal (14.6%) Mur ligase, central (14.6%) Mur-like, catalytic domain superfamily (14.6%)" YANPTLLR root "4.1.2.13 (52.2%) 2.7.13.3 (30.4%) 3.1.4.52 (17.4%)" "fructose-bisphosphate aldolase (52.2%) histidine kinase (30.4%) cyclic-guanylate-specific phosphodiesterase (17.4%)" "GO:0005975 (12.3%) GO:0006096 (8.9%) GO:0030388 (8.9%)" "GO:0005886 (5.6%) GO:0005576 (0.6%)" "GO:0008270 (21.2%) GO:0004332 (11.2%) GO:0016832 (10.1%)" "carbohydrate metabolic process (12.3%) glycolytic process (8.9%) fructose 1,6-bisphosphate metabolic process (8.9%)" "plasma membrane (5.6%) extracellular region (0.6%)" "zinc ion binding (21.2%) fructose-bisphosphate aldolase activity (11.2%) aldehyde-lyase activity (10.1%)" "IPR000771 (13.8%) IPR050246 (13.8%) IPR013785 (13.4%)" "Fructose-bisphosphate aldolase, class-II (13.8%) Class II Fructose-bisphosphate Aldolase (13.8%) Aldolase-type TIM barrel (13.4%)" MVDTTDEWLTTR Bacteria Bacteria 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (18.6%)" "GO:0005737 (20%) GO:0016020 (1.4%)" "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (18.6%)" "cytoplasm (20%) membrane (1.4%)" "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" FDVDPEFSMDFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri MLDGVFR root "2.1.1.228 (33.3%) 2.7.13.3 (33.3%) 1.1.1.169 (11.1%)" "tRNA (guanine(37)-N(1))-methyltransferase (33.3%) histidine kinase (33.3%) 2-dehydropantoate 2-reductase (11.1%)" "GO:0005977 (24%) GO:0015808 (0.2%) GO:0042941 (0.2%)" "GO:0005886 (24.2%) GO:0005964 (22.5%) GO:0009279 (0.2%)" "GO:0005516 (24%) GO:0016301 (1.1%) GO:0005304 (0.2%)" "glycogen metabolic process (24%) L-alanine transport (0.2%) D-alanine transmembrane transport (0.2%)" "plasma membrane (24.2%) phosphorylase kinase complex (22.5%) cell outer membrane (0.2%)" "calmodulin binding (24%) kinase activity (1.1%) L-valine transmembrane transporter activity (0.2%)" "IPR008734 (24.1%) IPR011613 (24%) IPR008928 (23.9%)" "Phosphorylase kinase alpha/beta subunit (24.1%) GH15-like domain (24%) Six-hairpin glycosidase superfamily (23.9%)" TEEETYFAQSDLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0016787 (97%) GO:0052689 (3%)" "hydrolase activity (97%) carboxylic ester hydrolase activity (3%)" "IPR002018 (20.5%) IPR019826 (19.9%) IPR029058 (19.9%)" "Carboxylesterase, type B (20.5%) Carboxylesterase type B, active site (19.9%) Alpha/Beta hydrolase fold (19.9%)" KADNPDWYFNALAGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (34.5%) IPR050330 (33.6%) IPR036737 (31.8%)" "OmpA-like domain (34.5%) Bacterial Outer Membrane Structural/Functional (33.6%) OmpA-like domain superfamily (31.8%)" GLVETDWLGKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (12.9%) IPR050288 (12.9%) IPR002772 (12.6%)" "Glycoside hydrolase, family 3, N-terminal (12.9%) Cellulose-degrading glycosyl hydrolase 3 (12.9%) Glycoside hydrolase family 3 C-terminal domain (12.6%)" KATYTPVLQDDGTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" TFGATVEGSPSMSTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (22.3%) IPR006316 (22.3%) IPR023026 (22.3%)" "Tryptophan synthase beta chain-like, PALP domain (22.3%) Tryptophan synthase, beta chain-like (22.3%) Tryptophan synthase beta chain/beta chain-like (22.3%)" NQELLNAYSYAQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" EAESSFKDANFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025665 (89.3%) IPR036709 (10.7%)" "Outer membrane protein, beta-barrel domain 2 (89.3%) Autotransporter beta-domain superfamily (10.7%)" ELADLKDFLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (47.6%) GO:0016887 (47.6%) GO:0016740 (2.9%)" "ATP binding (47.6%) ATP hydrolysis activity (47.6%) transferase activity (2.9%)" "IPR003439 (16.4%) IPR032781 (16.4%) IPR003593 (16.1%)" "ABC transporter-like, ATP-binding domain (16.4%) ABC-transporter extension domain (16.4%) AAA+ ATPase domain (16.1%)" FSTSTFR root "3.4.11.7 (44.4%) 2.7.7.7 (22.2%) 1.3.8.6 (11.1%)" "glutamyl aminopeptidase (44.4%) DNA-directed DNA polymerase (22.2%) glutaryl-CoA dehydrogenase (ETF) (11.1%)" "GO:0006508 (4.1%) GO:0006396 (2.9%) GO:0000226 (2.2%)" "GO:0016020 (9.8%) GO:0009279 (9.5%) GO:0005737 (4.1%)" "GO:0004525 (2.9%) GO:0008239 (2.5%) GO:0070008 (2.5%)" "proteolysis (4.1%) RNA processing (2.9%) microtubule cytoskeleton organization (2.2%)" "membrane (9.8%) cell outer membrane (9.5%) cytoplasm (4.1%)" "ribonuclease III activity (2.9%) dipeptidyl-peptidase activity (2.5%) serine-type exopeptidase activity (2.5%)" "IPR036942 (8.7%) IPR011042 (3.2%) IPR015920 (3.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (8.7%) Six-bladed beta-propeller, TolB-like (3.2%) Cellobiose dehydrogenase-like, cytochrome domain (3.2%)" ALPWSFANYLSGPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (52%) IPR050811 (48%)" "PBP domain (52%) Phosphate-binding ABC transporter substrate-binding (48%)" AQFAQYGMNNLPEEYLENYAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.9%) GO:0043335 (15.9%) GO:0051083 (15.9%)" GO:0005737 (4.4%) "GO:0003755 (15.9%) GO:0043022 (15.9%) GO:0044183 (15.9%)" "protein transport (15.9%) protein unfolding (15.9%) 'de novo' cotranslational protein folding (15.9%)" cytoplasm (4.4%) "peptidyl-prolyl cis-trans isomerase activity (15.9%) ribosome binding (15.9%) protein folding chaperone (15.9%)" "IPR005215 (19.6%) IPR008881 (19.6%) IPR027304 (18.5%)" "Trigger factor (19.6%) Trigger factor, ribosome-binding, bacterial (19.6%) Trigger factor/SurA domain superfamily (18.5%)" GENVRDWLYVVDHAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (49.8%) GO:0016020 (0.3%) GO:0008460 (49.8%) nucleotide-sugar metabolic process (49.8%) membrane (0.3%) dTDP-glucose 4,6-dehydratase activity (49.8%) "IPR036291 (33.8%) IPR005888 (32.3%) IPR016040 (19.3%)" "NAD(P)-binding domain superfamily (33.8%) dTDP-glucose 4,6-dehydratase (32.3%) NAD(P)-binding domain (19.3%)" WVEVQLR root "2.7.6.5 (89.3%) 3.1.7.2 (8%) 3.4.-.- (1.5%)" "GTP diphosphokinase (89.3%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (8%) Acting on peptide bonds (peptidases) (1.5%)" "GO:0015969 (35.7%) GO:0015949 (0.1%) GO:0006388 (0.1%)" "GO:0005886 (35.7%) GO:0016020 (1.5%) GO:0005634 (0.1%)" "GO:0016301 (10.7%) GO:0016787 (8.9%) GO:0008728 (3.2%)" "guanosine tetraphosphate metabolic process (35.7%) nucleobase-containing small molecule interconversion (0.1%) tRNA splicing, via endonucleolytic cleavage and ligation (0.1%)" "plasma membrane (35.7%) membrane (1.5%) nucleus (0.1%)" "kinase activity (10.7%) hydrolase activity (8.9%) GTP diphosphokinase activity (3.2%)" "IPR007685 (9.4%) IPR043519 (9.4%) IPR004095 (9.4%)" "RelA/SpoT (9.4%) Nucleotidyltransferase superfamily (9.4%) TGS (9.4%)" NAAVNWTTVSTKPLGETYWQTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (42.9%) "GO:0052689 (42.9%) GO:0004557 (14.3%)" cell outer membrane (42.9%) "carboxylic ester hydrolase activity (42.9%) alpha-galactosidase activity (14.3%)" "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" ALDESPLESVELR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR007066 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 3 (9.3%)" SKVSEYCYTEQQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR001241 (8%) IPR002288 (8%) IPR003594 (8%)" "DNA topoisomerase, type IIA (8%) DNA gyrase B subunit, C-terminal (8%) Histidine kinase/HSP90-like ATPase domain (8%)" WGYFPAAAFAWK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.5%) IPR023996 (13.5%) IPR039426 (13.5%)" "TonB-dependent receptor-like, beta-barrel (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent receptor-like (13.5%)" VSAENVETTMTQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011250 (50%) IPR027385 (50%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (50%) Outer membrane protein, beta-barrel domain (50%)" LFGESHEQELAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030170 (100%) pyridoxal phosphate binding (100%) "IPR001608 (33.7%) IPR011078 (33.7%) IPR029066 (32.6%)" "Alanine racemase, N-terminal (33.7%) Pyridoxal phosphate homeostasis protein (33.7%) PLP-binding barrel (32.6%)" YGNHGGVWECPDLMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.65 (100%) levanase (100%) GO:0005987 (33.1%) GO:0005737 (33.1%) "GO:0004575 (33.1%) GO:0031219 (0.7%)" sucrose catabolic process (33.1%) cytoplasm (33.1%) "sucrose alpha-glucosidase activity (33.1%) levanase activity (0.7%)" "IPR001362 (14.5%) IPR013148 (14.5%) IPR013189 (14.5%)" "Glycoside hydrolase, family 32 (14.5%) Glycosyl hydrolase family 32, N-terminal (14.5%) Glycosyl hydrolase family 32, C-terminal (14.5%)" LAGVEHEFSSVPGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR011773 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) DNA-directed RNA polymerase, alpha subunit (16.7%)" LDGFDPGMDSYVQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.2%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.2%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" ATPQVDLTFFHK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "IPR025049 (57.1%) IPR042278 (42.9%)" "Fimbrillin-like 1 (57.1%) Fimbrillin-like 1, N-terminal (42.9%)" LYMEGQLNYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" MPSLVPVYEEDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" KGADFANPSYVQLHPTCLPVHGTNQSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (18%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (18%)" "IPR003953 (14.3%) IPR011280 (14.3%) IPR015939 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%)" GWLTPEQAEEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (47.5%) GO:0003746 (52.5%) cytoplasm (47.5%) translation elongation factor activity (52.5%) "IPR014039 (20.6%) IPR036402 (20.6%) IPR001816 (19.6%)" "Translation elongation factor EFTs/EF1B, dimerisation (20.6%) Elongation factor Ts, dimerisation domain superfamily (20.6%) Translation elongation factor EFTs/EF1B (19.6%)" YNNTEQVWGSNATTNSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (39.1%) GO:0009279 (60.9%) iron ion transport (39.1%) cell outer membrane (60.9%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YSTATWSGDLATR Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.2.1.177 (58.8%) 3.2.1.- (41.2%)" "alpha-D-xyloside xylohydrolase (58.8%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (41.2%)" GO:0005975 (33.7%) "GO:0030246 (32.4%) GO:0004553 (31.4%) GO:0061634 (2.2%)" carbohydrate metabolic process (33.7%) "carbohydrate binding (32.4%) hydrolase activity, hydrolyzing O-glycosyl compounds (31.4%) alpha-D-xyloside xylohydrolase (2.2%)" "IPR000322 (10.9%) IPR048395 (10.9%) IPR051816 (10.9%)" "Glycoside hydrolase family 31, TIM barrel domain (10.9%) Glycosyl hydrolase family 31, C-terminal domain (10.9%) Glycosyl Hydrolase Family 31 (10.9%)" ATGSQLLNVFDKDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" KDLVNVQALAQYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (3.7%) GO:0016020 (92.6%) GO:0008233 (3.7%) proteolysis (3.7%) membrane (92.6%) peptidase activity (3.7%) "IPR006665 (27.2%) IPR050330 (27.2%) IPR036737 (25%)" "OmpA-like domain (27.2%) Bacterial Outer Membrane Structural/Functional (27.2%) OmpA-like domain superfamily (25%)" TDNGEVVYGEPVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.6%) GO:0005737 (48.6%)" GO:0016787 (2.7%) "extracellular region (48.6%) cytoplasm (48.6%)" hydrolase activity (2.7%) "IPR028994 (22.3%) IPR003284 (14.9%) IPR022045 (13.2%)" "Integrin alpha, N-terminal (22.3%) Salmonella virulence plasmid 65kDa B protein (14.9%) Insecticide toxin TcdB middle/N-terminal (13.2%)" GLEELGSEFNLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR000943 (10%) IPR007624 (10%) IPR007627 (10%)" "RNA polymerase sigma-70 (10%) RNA polymerase sigma-70 region 3 (10%) RNA polymerase sigma-70 region 2 (10%)" EVDNMCVVAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae NSKGELLQPNAQPGDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" EREVELAFEGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" TPNVYGYYTSLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR011990 (32.9%) IPR033985 (32.9%)" "RagB/SusD domain (34.1%) Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (32.9%)" ELAGYDPTR Bacteria Bacteria 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) "GO:0006428 (14.2%) GO:0006633 (0.4%)" GO:0005737 (14.2%) "GO:0000049 (14.2%) GO:0004822 (14.2%) GO:0005524 (14.2%)" "isoleucyl-tRNA aminoacylation (14.2%) fatty acid biosynthetic process (0.4%)" cytoplasm (14.2%) "tRNA binding (14.2%) isoleucine-tRNA ligase activity (14.2%) ATP binding (14.2%)" "IPR002300 (11.9%) IPR002301 (11.9%) IPR013155 (11.9%)" "Aminoacyl-tRNA synthetase, class Ia (11.9%) Isoleucine-tRNA ligase (11.9%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (11.9%)" LPQLGGVNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) ESEPDLYNALK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.8%) GO:0005829 (17.7%) "GO:0004612 (17.8%) GO:0005524 (17.8%) GO:0046872 (16.9%)" gluconeogenesis (17.8%) cytosol (17.7%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.8%) ATP binding (17.8%) metal ion binding (16.9%)" "IPR001272 (25.5%) IPR013035 (25.4%) IPR008210 (24.6%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.5%) Phosphoenolpyruvate carboxykinase, C-terminal (25.4%) Phosphoenolpyruvate carboxykinase, N-terminal (24.6%)" SPAPDVLMGLTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.4%) IPR023996 (13.4%) IPR036942 (13.4%)" "TonB-dependent receptor-like, beta-barrel (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.4%)" QGLFYATGLNEGNDVGSTYYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" GNMNYNMDPGWSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LVLAANVAK Bacteria Bacteria 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (24.4%) "GO:0005737 (24.4%) GO:0005886 (1.3%)" "GO:0004814 (24.4%) GO:0005524 (24.4%) GO:0022857 (1.3%)" arginyl-tRNA aminoacylation (24.4%) "cytoplasm (24.4%) plasma membrane (1.3%)" "arginine-tRNA ligase activity (24.4%) ATP binding (24.4%) transmembrane transporter activity (1.3%)" "IPR001278 (12.5%) IPR001412 (12.5%) IPR005148 (12.5%)" "Arginine-tRNA ligase (12.5%) Aminoacyl-tRNA synthetase, class I, conserved site (12.5%) Arginyl tRNA synthetase N-terminal domain (12.5%)" VGDLSFEGLELATSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" YFTNLAWSPDSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" CGACMNTCPVYR Bacteria Bacteria "GO:0006089 (33.3%) GO:1903457 (0.1%)" "GO:0046872 (33.2%) GO:0051539 (33.2%) GO:0051536 (0.2%)" "lactate metabolic process (33.3%) lactate catabolic process (0.1%)" "metal ion binding (33.2%) 4 iron, 4 sulfur cluster binding (33.2%) iron-sulfur cluster binding (0.2%)" "IPR004452 (13.5%) IPR017896 (13.5%) IPR017900 (13.5%)" "L-lactate oxidation iron-sulfur protein LutB/LldF (13.5%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (13.5%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (13.5%)" SGWYQLQGQDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (69.4%) "GO:0016787 (22.2%) GO:0016829 (8.3%)" carbohydrate metabolic process (69.4%) "hydrolase activity (22.2%) lyase activity (8.3%)" "IPR013783 (24.3%) IPR017853 (24.3%) IPR031965 (24.3%)" "Immunoglobulin-like fold (24.3%) Glycoside hydrolase superfamily (24.3%) Starch-binding module 26 (24.3%)" DGPTLFCPPLGHVQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.1.21 (95.2%) 2.1.2.- (4.8%)" "phosphoribosylglycinamide formyltransferase 2 (95.2%) Hydroxymethyl-, formyl- and related transferases (4.8%)" "GO:0006189 (15.9%) GO:0006164 (0.4%) GO:0009152 (0.4%)" GO:0005829 (16.7%) "GO:0005524 (16.7%) GO:0000287 (16.3%) GO:0004644 (16.3%)" "'de novo' IMP biosynthetic process (15.9%) purine nucleotide biosynthetic process (0.4%) purine ribonucleotide biosynthetic process (0.4%)" cytosol (16.7%) "ATP binding (16.7%) magnesium ion binding (16.3%) phosphoribosylglycinamide formyltransferase activity (16.3%)" "IPR003135 (12.7%) IPR011761 (12.7%) IPR048740 (12.7%)" "ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type (12.7%) ATP-grasp fold (12.7%) PurT, C-terminal (12.7%)" FFDLGTDHYYYDDYENDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) "GO:0003824 (35.3%) GO:0016787 (14.7%)" carbohydrate metabolic process (50%) "catalytic activity (35.3%) hydrolase activity (14.7%)" "IPR004300 (34%) IPR052046 (34%) IPR011330 (32%)" "Glycoside hydrolase family 57, N-terminal domain (34%) Glycosyl hydrolase family 57 (34%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32%)" VDWTWDNQFDYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" MDLGVLSVR root "GO:0005886 (31%) GO:0045259 (31%) GO:0016020 (0.9%)" "GO:0046933 (31%) GO:0016787 (6.2%)" "plasma membrane (31%) proton-transporting ATP synthase complex (31%) membrane (0.9%)" "proton-transporting ATP synthase activity, rotational mechanism (31%) hydrolase activity (6.2%)" "IPR000711 (49.3%) IPR026015 (49.3%) IPR046623 (1.4%)" "ATPase, OSCP/delta subunit (49.3%) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily (49.3%) Domain of unknown function DUF6536 (1.4%)" YLLAGYPWFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) "GO:0005980 (33.1%) GO:0005975 (0.2%)" GO:0016020 (0.3%) "GO:0004134 (33.1%) GO:0004135 (33.1%) GO:0003677 (0.1%)" "glycogen catabolic process (33.1%) carbohydrate metabolic process (0.2%)" membrane (0.3%) "4-alpha-glucanotransferase activity (33.1%) amylo-alpha-1,6-glucosidase activity (33.1%) DNA binding (0.1%)" "IPR032790 (20.1%) IPR008928 (20%) IPR010401 (20%)" "Glycogen debranching enzyme, C-terminal (20.1%) Six-hairpin glycosidase superfamily (20%) Glycogen debranching enzyme (20%)" YWGEPFPVYYK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (19.8%) "GO:0005829 (19.8%) GO:0005739 (0.8%)" "GO:0004823 (19.9%) GO:0005524 (19.9%) GO:0002161 (19.7%)" leucyl-tRNA aminoacylation (19.8%) "cytosol (19.8%) mitochondrion (0.8%)" "leucine-tRNA ligase activity (19.9%) ATP binding (19.9%) aminoacyl-tRNA deacylase activity (19.7%)" "IPR002302 (12.4%) IPR025709 (12.3%) IPR014729 (12.3%)" "Leucine-tRNA ligase (12.4%) Leucyl-tRNA synthetase, editing domain (12.3%) Rossmann-like alpha/beta/alpha sandwich fold (12.3%)" GNAGVYLFQVTNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR027304 (26.6%) IPR046357 (26.6%) IPR052029 (26.6%)" "Trigger factor/SurA domain superfamily (26.6%) Peptidyl-prolyl cis-trans isomerase domain superfamily (26.6%) Periplasmic chaperone PpiD (26.6%)" DLNDAVVKETVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.6%) IPR027304 (25.3%) IPR046357 (25.3%)" "Periplasmic chaperone PpiD (26.6%) Trigger factor/SurA domain superfamily (25.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.3%)" LMDLGCYR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006412 (16.7%) GO:0015031 (0%) GO:0006351 (0%)" "GO:0015935 (16.7%) GO:0005829 (16.7%) GO:0016020 (0.1%)" "GO:0003735 (16.7%) GO:0019843 (16.7%) GO:0000049 (16.2%)" "translation (16.7%) protein transport (0%) DNA-templated transcription (0%)" "small ribosomal subunit (16.7%) cytosol (16.7%) membrane (0.1%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%) tRNA binding (16.2%)" "IPR001892 (20.1%) IPR010979 (20%) IPR027437 (20%)" "Small ribosomal subunit protein uS13 (20.1%) Small ribosomal subunit protein uS13-like, H2TH (20%) Small ribosomal subunit protein uS13, C-terminal (20%)" GQTSDLLTNVSSGTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" FADYCLGATAADGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) LTGNLFADLTPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" QVVYQVGYYSVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.9%) IPR001375 (21.4%) IPR011042 (21.4%)" "WD40-like beta-propeller (21.9%) Peptidase S9, prolyl oligopeptidase, catalytic domain (21.4%) Six-bladed beta-propeller, TolB-like (21.4%)" VVDHLLVFK Bacteria Bacteria 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0006412 (11.4%) GO:0006417 (11.4%)" GO:0005737 (11.4%) "GO:0003677 (14.3%) GO:0005524 (14.3%) GO:0016887 (14.3%)" "translation (11.4%) regulation of translation (11.4%)" cytoplasm (11.4%) "DNA binding (14.3%) ATP binding (14.3%) ATP hydrolysis activity (14.3%)" "IPR032524 (12.7%) IPR051309 (12.7%) IPR003439 (12.6%)" "ABC transporter Uup, C-terminal (12.7%) ABC transporter ABCF subfamily ATPase (12.7%) ABC transporter-like, ATP-binding domain (12.6%)" FCTGTDTSDWEKFEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.3%) IPR032466 (47.7%)" "Uronate isomerase (52.3%) Metal-dependent hydrolase (47.7%)" EQGCNALVVFLGNFGPETPETLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006004 (31.9%) GO:0005996 (1.4%)" GO:0005737 (33.3%) "GO:0008736 (31.9%) GO:0016861 (1.4%)" "fucose metabolic process (31.9%) monosaccharide metabolic process (1.4%)" cytoplasm (33.3%) "L-fucose isomerase activity (31.9%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1.4%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" FETFPVWNLPLK root 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (33.3%) GO:0051301 (6.7%)" "GO:0008233 (33.3%) GO:0003824 (20%) GO:0016787 (6.7%)" "proteolysis (33.3%) cell division (6.7%)" "peptidase activity (33.3%) catalytic activity (20%) hydrolase activity (6.7%)" "IPR048441 (44.7%) IPR048496 (44.7%) IPR014999 (9.8%)" "DUF1846, C-terminal (44.7%) DUF1846, N-terminal domain (44.7%) Family of unknown function DUF1846 (9.8%)" GLGVDAMFQGTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" DGEQVPGCQLNTVEK Pseudomonadati Bacteria Pseudomonadati 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.8%) GO:0005737 (19.1%) "GO:0003852 (20.8%) GO:0003985 (19.1%) GO:0030145 (19.1%)" L-leucine biosynthetic process (20.8%) cytoplasm (19.1%) "2-isopropylmalate synthase activity (20.8%) acetyl-CoA C-acetyltransferase activity (19.1%) manganese ion binding (19.1%)" "IPR000891 (12.7%) IPR002034 (12.7%) IPR013785 (12.7%)" "Pyruvate carboxyltransferase (12.7%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.7%) Aldolase-type TIM barrel (12.7%)" MQEAGFELR root 2.4.1.21 (100%) starch synthase (100%) "GO:0016757 (82.4%) GO:0051536 (5.9%) GO:0016829 (3.9%)" "glycosyltransferase activity (82.4%) iron-sulfur cluster binding (5.9%) lyase activity (3.9%)" "IPR013534 (84.3%) IPR007197 (5.9%) IPR040087 (5.9%)" "Starch synthase, catalytic domain (84.3%) Radical SAM (5.9%) Protein MJ0021-like (5.9%)" EATSDLTGER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.86 (92.1%) 1.1.1.- (7.9%)" "ketol-acid reductoisomerase (NADP(+)) (92.1%) With NAD(+) or NADP(+) as acceptor (7.9%)" "GO:0009097 (21%) GO:0009099 (21%)" GO:0070013 (0.2%) "GO:0004455 (21%) GO:0046872 (20.8%) GO:0016853 (15.9%)" "isoleucine biosynthetic process (21%) L-valine biosynthetic process (21%)" intracellular organelle lumen (0.2%) "ketol-acid reductoisomerase activity (21%) metal ion binding (20.8%) isomerase activity (15.9%)" "IPR000506 (16.7%) IPR013023 (16.7%) IPR013116 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) Ketol-acid reductoisomerase (16.7%) Ketol-acid reductoisomerase, N-terminal (16.7%)" HVLDSELTNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.3 (50%) 2.7.2.4 (50%)" "homoserine dehydrogenase (50%) aspartate kinase (50%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" GFGSFNLK root "GO:0030261 (20.9%) GO:0019478 (2.3%)" "GO:0005829 (23.3%) GO:0005737 (2.3%)" "GO:0003677 (23.3%) GO:0030527 (23.3%) GO:0003884 (2.3%)" "chromosome condensation (20.9%) D-amino acid catabolic process (2.3%)" "cytosol (23.3%) cytoplasm (2.3%)" "DNA binding (23.3%) structural constituent of chromatin (23.3%) D-amino-acid oxidase activity (2.3%)" "IPR000119 (41.7%) IPR010992 (37.5%) IPR001509 (4.2%)" "Histone-like DNA-binding protein (41.7%) Integration host factor (IHF)-like DNA-binding domain superfamily (37.5%) NAD-dependent epimerase/dehydratase (4.2%)" VGGGDSFSGGLLHGLLTK Bacteria Bacteria "2.7.1.92 (58.3%) 2.7.1.45 (41.7%)" "5-dehydro-2-deoxygluconokinase (58.3%) 2-dehydro-3-deoxygluconokinase (41.7%)" "GO:0016301 (91.5%) GO:0047590 (4.7%) GO:0008673 (3.9%)" "kinase activity (91.5%) 5-dehydro-2-deoxygluconokinase activity (4.7%) 2-dehydro-3-deoxygluconokinase activity (3.9%)" "IPR029056 (33.5%) IPR011611 (33%) IPR052700 (33%)" "Ribokinase-like (33.5%) Carbohydrate kinase PfkB (33%) Carbohydrate kinase PfkB-like (33%)" TAYPVALGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004826 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%)" "IPR002319 (14.3%) IPR004188 (14.3%) IPR004529 (14.3%)" "Phenylalanyl-tRNA synthetase (14.3%) Phenylalanine-tRNA ligase, class II, N-terminal (14.3%) Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (14.3%)" YAALGVDTDKALETLEK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.8%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.8%)" AGTQLGEPELLFEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" LYFDELTFER root "6.3.5.5 (92.2%) 6.3.4.16 (7.8%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (92.2%) carbamoyl-phosphate synthase (ammonia) (7.8%)" "GO:0006541 (14%) GO:0006221 (11%) GO:0006526 (11%)" "GO:0005737 (14%) GO:0005951 (0%)" "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (14%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (11%) L-arginine biosynthetic process (11%)" "cytoplasm (14%) carbamoyl-phosphate synthase complex (0%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (14%)" "IPR016185 (10.1%) IPR005479 (10.1%) IPR011761 (10.1%)" "Pre-ATP-grasp domain superfamily (10.1%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%)" LNMKPQEMADFLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (17.4%) GO:0006085 (15.9%)" GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0008776 (17.4%) GO:0000287 (15.9%)" "acetate metabolic process (17.4%) acetyl-CoA biosynthetic process (15.9%)" cytoplasm (15.9%) "ATP binding (17.4%) acetate kinase activity (17.4%) magnesium ion binding (15.9%)" "IPR000890 (25.3%) IPR004372 (25.3%) IPR023865 (25.3%)" "Aliphatic acid kinase, short-chain (25.3%) Acetate/propionate kinase (25.3%) Aliphatic acid kinase, short-chain, conserved site (25.3%)" SPLLLVDNVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.6%) IPR023996 (13.6%) IPR023997 (13.6%)" "TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.6%)" YLTGDSHVFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (62.5%) IPR008160 (37.5%)" "Domain of unknown function DUF4988 (62.5%) Collagen triple helix repeat (37.5%)" DAFMTSLPQEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.1%) IPR028053 (17.1%) IPR028055 (17.1%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.1%) Membrane insertase YidC, N-terminal (17.1%) Membrane insertase YidC/Oxa/ALB, C-terminal (17.1%)" QWQDLMFGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.7%) IPR012000 (12.7%) IPR012001 (12.7%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.7%) Thiamine pyrophosphate enzyme, central domain (12.7%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.7%)" KLDLLLR root "2.7.4.1 (51.5%) 6.1.1.3 (8.2%) 2.1.1.107 (3.1%)" "ATP-polyphosphate phosphotransferase (51.5%) threonine--tRNA ligase (8.2%) uroporphyrinogen-III C-methyltransferase (3.1%)" "GO:0006799 (5.4%) GO:0015744 (1.6%) GO:0071897 (1.2%)" "GO:0009358 (5.4%) GO:0016020 (3.4%) GO:0005886 (3%)" "GO:0005524 (9.1%) GO:0046872 (5.9%) GO:0008976 (5.4%)" "polyphosphate biosynthetic process (5.4%) succinate transport (1.6%) DNA biosynthetic process (1.2%)" "polyphosphate kinase complex (5.4%) membrane (3.4%) plasma membrane (3%)" "ATP binding (9.1%) metal ion binding (5.9%) polyphosphate kinase activity (5.4%)" "IPR003414 (3.5%) IPR025200 (3.5%) IPR041108 (3.5%)" "Polyphosphate kinase (3.5%) Polyphosphate kinase C-terminal domain 2 (3.5%) Polyphosphate kinase, C-terminal domain 1 (3.5%)" LYVNFDTNKAEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR025970 (50%) IPR032187 (50%)" "SusE outer membrane protein (50%) Outer membrane protein SusF/SusE-like, C-terminal (50%)" LLAVLQSGEPDAAFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003593 (25.3%) IPR003959 (25.3%) IPR051396 (25.3%)" "AAA+ ATPase domain (25.3%) ATPase, AAA-type, core (25.3%) Bacterial Antiviral Defense Nuclease (25.3%)" FAELLGEVLGDTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (40%) GO:0016491 (10%)" "iron ion binding (50%) peroxidase activity (40%) oxidoreductase activity (10%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" FYHDLVFDGFK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (33.8%) IPR011990 (31.7%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (31.7%)" SRDTNLGVVEGMQFDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (21.4%) GO:0005737 (10.9%) "GO:0005524 (21.4%) GO:0140662 (21.4%) GO:0016853 (13.9%)" protein refolding (21.4%) cytoplasm (10.9%) "ATP binding (21.4%) ATP-dependent protein folding chaperone (21.4%) isomerase activity (13.9%)" "IPR001844 (18.4%) IPR002423 (18.4%) IPR027409 (18.1%)" "Chaperonin Cpn60/GroEL (18.4%) Chaperonin Cpn60/GroEL/TCP-1 family (18.4%) GroEL-like apical domain superfamily (18.1%)" NQYYGLPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.4%) IPR033985 (34.4%) IPR012944 (31.3%)" "Tetratricopeptide-like helical domain superfamily (34.4%) SusD-like, N-terminal (34.4%) RagB/SusD domain (31.3%)" LLLLGGGGR root "6.3.4.13 (95.5%) 6.3.3.1 (2.1%) 2.1.2.2 (1.4%)" "phosphoribosylamine--glycine ligase (95.5%) phosphoribosylformylglycinamidine cyclo-ligase (2.1%) phosphoribosylglycinamide formyltransferase 1 (1.4%)" "GO:0006189 (19.1%) GO:0009113 (18.6%) GO:0046084 (0.8%)" "GO:0005829 (0.8%) GO:0016020 (0.5%) GO:0005886 (0.1%)" "GO:0004637 (19.3%) GO:0046872 (19.2%) GO:0005524 (19.2%)" "'de novo' IMP biosynthetic process (19.1%) purine nucleobase biosynthetic process (18.6%) adenine biosynthetic process (0.8%)" "cytosol (0.8%) membrane (0.5%) plasma membrane (0.1%)" "phosphoribosylamine-glycine ligase activity (19.3%) metal ion binding (19.2%) ATP binding (19.2%)" "IPR020562 (9.8%) IPR000115 (9.8%) IPR016185 (9.8%)" "Phosphoribosylglycinamide synthetase, N-terminal (9.8%) Phosphoribosylglycinamide synthetase (9.8%) Pre-ATP-grasp domain superfamily (9.8%)" LCVAYEGMER Bacteria Bacteria "2.4.1.227 (99.5%) 6.3.4.4 (0.5%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (99.5%) adenylosuccinate synthase (0.5%)" "GO:0005975 (11.7%) GO:0030259 (11.7%) GO:0008360 (11.7%)" GO:0005886 (11.7%) "GO:0050511 (11.7%) GO:0051991 (6.5%) GO:0016758 (0.1%)" "carbohydrate metabolic process (11.7%) obsolete lipid glycosylation (11.7%) regulation of cell shape (11.7%)" plasma membrane (11.7%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.7%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (6.5%) hexosyltransferase activity (0.1%)" "IPR004276 (33.5%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.5%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" LDFFLQGNQWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) LKVPESVMGVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.8%) "GO:0005886 (16.5%) GO:0016020 (0.6%)" "GO:0016655 (16.8%) GO:0051537 (16.8%) GO:0046872 (16.5%)" sodium ion transport (16.8%) "plasma membrane (16.5%) membrane (0.6%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.8%) 2 iron, 2 sulfur cluster binding (16.8%) metal ion binding (16.5%)" "IPR001041 (10.1%) IPR001433 (10.1%) IPR008333 (10.1%)" "2Fe-2S ferredoxin-type iron-sulfur binding domain (10.1%) Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" GYSNAYGDLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.4%) IPR012944 (33.3%) IPR011990 (32.3%)" "SusD-like, N-terminal (34.4%) RagB/SusD domain (33.3%) Tetratricopeptide-like helical domain superfamily (32.3%)" NLLLFAR root "2.7.13.3 (17.7%) 4.6.1.1 (10.1%) 5.6.2.4 (8.9%)" "histidine kinase (17.7%) adenylate cyclase (10.1%) DNA 3'-5' helicase (8.9%)" "GO:0006412 (7.2%) GO:0006605 (3.3%) GO:0043952 (3.3%)" "GO:0005886 (7.2%) GO:0015935 (7.1%) GO:0016020 (2.2%)" "GO:0003735 (7.2%) GO:0019843 (7.2%) GO:0000049 (6.2%)" "translation (7.2%) protein targeting (3.3%) protein transport by the Sec complex (3.3%)" "plasma membrane (7.2%) small ribosomal subunit (7.1%) membrane (2.2%)" "structural constituent of ribosome (7.2%) rRNA binding (7.2%) tRNA binding (6.2%)" "IPR023798 (5.5%) IPR036823 (5.5%) IPR000235 (5.5%)" "Small ribosomal subunit protein uS7 domain (5.5%) Small ribosomal subunit protein uS7 domain superfamily (5.5%) Small ribosomal subunit protein uS7 (5.5%)" QLNVTQMDVFSR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.21.92 (100%) endopeptidase Clp (100%) GO:0006515 (16.7%) "GO:0009368 (16.7%) GO:0005737 (16.4%) GO:0016020 (0.3%)" "GO:0004176 (16.7%) GO:0004252 (16.7%) GO:0051117 (16.7%)" protein quality control for misfolded or incompletely synthesized proteins (16.7%) "endopeptidase Clp complex (16.7%) cytoplasm (16.4%) membrane (0.3%)" "ATP-dependent peptidase activity (16.7%) serine-type endopeptidase activity (16.7%) ATPase binding (16.7%)" "IPR001907 (28.7%) IPR023562 (28.7%) IPR029045 (28.7%)" "ATP-dependent Clp protease proteolytic subunit (28.7%) Clp protease proteolytic subunit /Translocation-enhancing protein TepA (28.7%) ClpP/crotonase-like domain superfamily (28.7%)" SPLQDEYLEK Bacteria Bacteria 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (25.3%) GO:0006065 (18.2%) GO:0006072 (1.1%)" "GO:0051287 (26.3%) GO:0003979 (25.3%) GO:0003677 (2.6%)" "polysaccharide biosynthetic process (25.3%) UDP-glucuronate biosynthetic process (18.2%) glycerol-3-phosphate metabolic process (1.1%)" "NAD binding (26.3%) UDP-glucose 6-dehydrogenase activity (25.3%) DNA binding (2.6%)" "IPR001732 (11.2%) IPR036291 (11.2%) IPR017476 (10.9%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.2%) NAD(P)-binding domain superfamily (11.2%) UDP-glucose/GDP-mannose dehydrogenase (10.9%)" LGLANAADGLNGDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" GLAKPVGSMTQYDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (29.2%) GO:0008654 (29.2%)" GO:0016020 (12.5%) GO:0004512 (29.2%) "inositol biosynthetic process (29.2%) phospholipid biosynthetic process (29.2%)" membrane (12.5%) inositol-3-phosphate synthase activity (29.2%) "IPR002587 (33.6%) IPR013021 (33.2%) IPR036291 (33.2%)" "Myo-inositol-1-phosphate synthase (33.6%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.2%) NAD(P)-binding domain superfamily (33.2%)" TQVCNLLDQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" QALDNLTPQVEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.1%) GO:0015935 (20.1%) "GO:0003735 (20.1%) GO:0019843 (20.1%) GO:0000049 (19.8%)" translation (20.1%) small ribosomal subunit (20.1%) "structural constituent of ribosome (20.1%) rRNA binding (20.1%) tRNA binding (19.8%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" EQVLLNTWYGGEMKK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.6%) GO:0005829 (17.6%) "GO:0004612 (17.6%) GO:0005524 (17.6%) GO:0046872 (17.3%)" gluconeogenesis (17.6%) cytosol (17.6%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.6%) ATP binding (17.6%) metal ion binding (17.3%)" "IPR001272 (25.2%) IPR008210 (25.2%) IPR013035 (24.9%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.2%) Phosphoenolpyruvate carboxykinase, N-terminal (25.2%) Phosphoenolpyruvate carboxykinase, C-terminal (24.9%)" ESATAYTMEVAAPGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (32.5%) IPR008978 (32.5%) IPR031107 (32.5%)" "Alpha crystallin/Hsp20 domain (32.5%) HSP20-like chaperone (32.5%) Small heat shock protein (32.5%)" DCFMVLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016740 (100%) transferase activity (100%) IPR029044 (100%) Nucleotide-diphospho-sugar transferases (100%) DGYETASYSDATYPTQRPGAADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" WGLVNNALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (23.1%) IPR057601 (23.1%) IPR008969 (17.9%)" "TonB-dependent receptor-like (23.1%) TonB-dependent transporter Oar-like, beta-barrel domain (23.1%) Carboxypeptidase-like, regulatory domain superfamily (17.9%)" LPLLDALK root "6.1.1.6 (39.1%) 2.7.7.49 (27.6%) 3.6.4.13 (9.8%)" "lysine--tRNA ligase (39.1%) RNA-directed DNA polymerase (27.6%) RNA helicase (9.8%)" "GO:0050852 (3.8%) GO:0045087 (3.3%) GO:0043123 (3.3%)" "GO:0005829 (5.8%) GO:0048471 (2.8%) GO:0005634 (2.3%)" "GO:0004197 (3.9%) GO:0005524 (3.7%) GO:0003676 (3.3%)" "T cell receptor signaling pathway (3.8%) innate immune response (3.3%) positive regulation of canonical NF-kappaB signal transduction (3.3%)" "cytosol (5.8%) perinuclear region of cytoplasm (2.8%) nucleus (2.3%)" "cysteine-type endopeptidase activity (3.9%) ATP binding (3.7%) nucleic acid binding (3.3%)" "IPR021109 (8.5%) IPR043502 (3.5%) IPR005162 (2.9%)" "Aspartic peptidase domain superfamily (8.5%) DNA/RNA polymerase superfamily (3.5%) Retrotransposon gag domain (2.9%)" VVVVGGDNYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.9%) GO:0006164 (0.2%)" GO:0005737 (20.1%) "GO:0004642 (20.1%) GO:0005524 (19.9%) GO:0046872 (19.9%)" "'de novo' IMP biosynthetic process (19.9%) purine nucleotide biosynthetic process (0.2%)" cytoplasm (20.1%) "phosphoribosylformylglycinamidine synthase activity (20.1%) ATP binding (19.9%) metal ion binding (19.9%)" "IPR010918 (11.3%) IPR055181 (11.3%) IPR010073 (11.2%)" "PurM-like, C-terminal domain (11.3%) FGAR-AT, PurM N-terminal-like domain (11.3%) Phosphoribosylformylglycinamidine synthase PurL (11.2%)" MQLLPLLSAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" KSGLAFVDNPAHAQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" SLYLEAEPMEYLTAAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0030246 (51.4%) GO:0016787 (48.6%)" "carbohydrate binding (51.4%) hydrolase activity (48.6%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" FTLQSLGK root "2.3.2.27 (50%) 4.1.2.27 (50%)" "RING-type E3 ubiquitin transferase (50%) sphinganine-1-phosphate aldolase (50%)" "GO:0016567 (5.2%) GO:0019752 (5.2%) GO:0030149 (5.2%)" "GO:0009279 (28.6%) GO:0005829 (6.5%) GO:0000151 (5.2%)" "GO:0008117 (5.2%) GO:0008270 (5.2%) GO:0030170 (5.2%)" "protein ubiquitination (5.2%) carboxylic acid metabolic process (5.2%) sphingolipid catabolic process (5.2%)" "cell outer membrane (28.6%) cytosol (6.5%) ubiquitin ligase complex (5.2%)" "sphinganine-1-phosphate aldolase activity (5.2%) zinc ion binding (5.2%) pyridoxal phosphate binding (5.2%)" "IPR008969 (10.2%) IPR012910 (10.2%) IPR023996 (10.2%)" "Carboxypeptidase-like, regulatory domain superfamily (10.2%) TonB-dependent receptor, plug domain (10.2%) TonB-dependent outer membrane protein, SusC/RagA (10.2%)" LMLDNFSVPDTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.19 (100%) nicotinate-nucleotide diphosphorylase (carboxylating) (100%) "GO:0009435 (25%) GO:0034213 (25%)" GO:0005737 (25%) GO:0004514 (25%) "NAD+ biosynthetic process (25%) quinolinate catabolic process (25%)" cytoplasm (25%) nicotinate-nucleotide diphosphorylase (carboxylating) activity (25%) "IPR002638 (14.5%) IPR004393 (14.5%) IPR022412 (14.5%)" "Quinolinate phosphoribosyl transferase, C-terminal (14.5%) Nicotinate-nucleotide pyrophosphorylase (14.5%) Quinolinate phosphoribosyl transferase, N-terminal (14.5%)" EGYPELAEAYK Bacteria Bacteria 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (23.2%) GO:0016491 (19.3%)" "iron ion binding (50%) peroxidase activity (23.2%) oxidoreductase activity (19.3%)" "IPR003251 (12.8%) IPR009040 (12.8%) IPR009078 (12.8%)" "Rubrerythrin, diiron-binding domain (12.8%) Ferritin-like diiron domain (12.8%) Ferritin-like superfamily (12.8%)" LPLVSTSAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (26.9%) IPR013780 (24.7%) IPR017853 (24.7%)" "Alpha-L-arabinofuranosidase, C-terminal (26.9%) Glycosyl hydrolase, all-beta (24.7%) Glycoside hydrolase superfamily (24.7%)" MSMLLNSAVFPGQQGGPLEHVLAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (16.7%) GO:0035999 (16.7%) GO:0032259 (8.3%)" GO:0005829 (16.7%) "GO:0004372 (16.7%) GO:0030170 (16.7%) GO:0008168 (8.3%)" "glycine biosynthetic process from serine (16.7%) tetrahydrofolate interconversion (16.7%) methylation (8.3%)" cytosol (16.7%) "glycine hydroxymethyltransferase activity (16.7%) pyridoxal phosphate binding (16.7%) methyltransferase activity (8.3%)" "IPR001085 (14.6%) IPR019798 (14.6%) IPR039429 (14.6%)" "Serine hydroxymethyltransferase (14.6%) Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.6%) Serine hydroxymethyltransferase-like domain (14.6%)" KHELQAPLYDPNEEPLMDNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.1.108 (53.2%) 4.2.1.59 (46.8%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (53.2%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (46.8%)" "GO:0009245 (14.3%) GO:0006633 (13.9%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (10.4%)" "lipid A biosynthetic process (14.3%) fatty acid biosynthetic process (13.9%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (10.4%)" "IPR004463 (14.9%) IPR013114 (14.9%) IPR010084 (14.4%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.9%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.9%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.4%)" TFLSWLLK root "2.6.1.- (93.5%) 2.3.1.12 (4.3%) 4.3.3.2 (2.2%)" "Transaminases (93.5%) dihydrolipoyllysine-residue acetyltransferase (4.3%) Transferred entry: 3.5.99.13 (2.2%)" "GO:0002224 (0.6%) GO:0006281 (0.6%) GO:0006508 (0.6%)" "GO:0016020 (5.5%) GO:0005737 (4.8%) GO:0005615 (0.6%)" "GO:0008483 (29.1%) GO:0030170 (29.1%) GO:0031405 (4.2%)" "toll-like receptor signaling pathway (0.6%) DNA repair (0.6%) proteolysis (0.6%)" "membrane (5.5%) cytoplasm (4.8%) extracellular space (0.6%)" "transaminase activity (29.1%) pyridoxal phosphate binding (29.1%) lipoic acid binding (4.2%)" "IPR004838 (13.4%) IPR004839 (13.4%) IPR050881 (13.4%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (13.4%) Aminotransferase, class I/classII, large domain (13.4%) LL-diaminopimelate aminotransferase (13.4%)" GVEETKFLLDTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (25%) GO:0005737 (25%) "GO:0004821 (25%) GO:0005524 (25%)" histidyl-tRNA aminoacylation (25%) cytoplasm (25%) "histidine-tRNA ligase activity (25%) ATP binding (25%)" "IPR004154 (12.7%) IPR006195 (12.7%) IPR015807 (12.7%)" "Anticodon-binding (12.7%) Aminoacyl-tRNA synthetase, class II (12.7%) Histidine-tRNA ligase (12.7%)" LYGYNNVELPTQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005146 (7.8%) IPR005147 (7.8%) IPR045060 (7.8%)" "B3/B4 tRNA-binding domain (7.8%) tRNA synthetase, B5-domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit (7.8%)" VQDSALEELVFTDSLPYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.5%) GO:0006164 (11.5%) GO:0009156 (7.7%)" "GO:0002189 (11.5%) GO:0005737 (11.5%)" "GO:0000287 (11.5%) GO:0004749 (11.5%) GO:0005524 (11.5%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.5%) purine nucleotide biosynthetic process (11.5%) ribonucleoside monophosphate biosynthetic process (7.7%)" "ribose phosphate diphosphokinase complex (11.5%) cytoplasm (11.5%)" "magnesium ion binding (11.5%) ribose phosphate diphosphokinase activity (11.5%) ATP binding (11.5%)" "IPR000836 (18.8%) IPR005946 (18.8%) IPR029057 (18.8%)" "Phosphoribosyltransferase domain (18.8%) Ribose-phosphate pyrophosphokinase (18.8%) Phosphoribosyltransferase-like (18.8%)" VGFLGYR root "3.6.1.1 (16.7%) 1.-.-.- (8.3%) 1.2.1.11 (8.3%)" "inorganic diphosphatase (16.7%) Oxidoreductases (8.3%) aspartate-semialdehyde dehydrogenase (8.3%)" "GO:0055085 (1.7%) GO:0006623 (1.5%) GO:0034058 (1.5%)" "GO:0005886 (28.7%) GO:0016020 (9.4%) GO:0005770 (1.5%)" "GO:0022857 (30%) GO:0003677 (1.5%) GO:0003700 (1.5%)" "transmembrane transport (1.7%) protein targeting to vacuole (1.5%) endosomal vesicle fusion (1.5%)" "plasma membrane (28.7%) membrane (9.4%) late endosome (1.5%)" "transmembrane transporter activity (30%) DNA binding (1.5%) DNA-binding transcription factor activity (1.5%)" "IPR011701 (19.4%) IPR036259 (19.4%) IPR020846 (16.3%)" "Major facilitator superfamily (19.4%) MFS transporter superfamily (19.4%) Major facilitator superfamily domain (16.3%)" LLDPLLVGK root 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0006364 (0.3%) GO:0042274 (0.3%) GO:0010038 (0.2%)" "GO:0005886 (21.5%) GO:0045259 (20.7%) GO:0009506 (0.8%)" "GO:0005524 (22.4%) GO:0046933 (20.7%) GO:0016787 (7.7%)" "rRNA processing (0.3%) ribosomal small subunit biogenesis (0.3%) response to metal ion (0.2%)" "plasma membrane (21.5%) proton-transporting ATP synthase complex (20.7%) plasmodesma (0.8%)" "ATP binding (22.4%) proton-transporting ATP synthase activity, rotational mechanism (20.7%) hydrolase activity (7.7%)" "IPR000194 (9.4%) IPR020003 (9.4%) IPR024034 (9.4%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (9.4%) ATPase, alpha/beta subunit, nucleotide-binding domain, active site (9.4%) ATPase, F1/V1 complex, beta/alpha subunit, C-terminal (9.4%)" TEVVEGEENTVLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR032283 (36.2%) IPR038081 (33.3%) IPR032299 (30.4%)" "Domain of unknown function DUF4984 (36.2%) CalX-like domain superfamily (33.3%) Protein of unknown function DUF4843 (30.4%)" ELHVDLPGLNER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" MNLKPLADR Bacteria Bacteria GO:0051085 (1%) GO:0005737 (16%) "GO:0005524 (16.6%) GO:0044183 (16.6%) GO:0046872 (16.6%)" obsolete chaperone cofactor-dependent protein refolding (1%) cytoplasm (16%) "ATP binding (16.6%) protein folding chaperone (16.6%) metal ion binding (16.6%)" "IPR011032 (29.8%) IPR020818 (29.8%) IPR037124 (29.8%)" "GroES-like superfamily (29.8%) GroES chaperonin family (29.8%) GroES chaperonin superfamily (29.8%)" AFPELFAPTTLDGMSWTEDAVAQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) TLWLDDNYFNAR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006355 (20%) GO:0000160 (0.2%)" "GO:0005829 (19.9%) GO:0032993 (19.9%)" "GO:0000156 (19.9%) GO:0000976 (19.9%) GO:0003677 (0.1%)" "regulation of DNA-templated transcription (20%) phosphorelay signal transduction system (0.2%)" "cytosol (19.9%) protein-DNA complex (19.9%)" "phosphorelay response regulator activity (19.9%) transcription cis-regulatory region binding (19.9%) DNA binding (0.1%)" "IPR001867 (17.5%) IPR036388 (17.4%) IPR001789 (17.3%)" "OmpR/PhoB-type DNA-binding domain (17.5%) Winged helix-like DNA-binding domain superfamily (17.4%) Signal transduction response regulator, receiver domain (17.3%)" TQLLLTPK root "1.97.1.12 (50%) 2.5.1.47 (50%)" "photosystem I (50%) cysteine synthase (50%)" "GO:0006605 (6%) GO:0043952 (6%) GO:0065002 (6%)" "GO:0016020 (57.5%) GO:0005886 (6.8%) GO:0005576 (0.4%)" "GO:0015450 (6.4%) GO:0016491 (1%) GO:0003677 (0.8%)" "protein targeting (6%) protein transport by the Sec complex (6%) intracellular protein transmembrane transport (6%)" "membrane (57.5%) plasma membrane (6.8%) extracellular region (0.4%)" "protein-transporting ATPase activity (6.4%) oxidoreductase activity (1%) DNA binding (0.8%)" "IPR006665 (25.6%) IPR050330 (25.5%) IPR036737 (25.3%)" "OmpA-like domain (25.6%) Bacterial Outer Membrane Structural/Functional (25.5%) OmpA-like domain superfamily (25.3%)" VAVLAAGSFYQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.7 (100%) 1-deoxy-D-xylulose-5-phosphate synthase (100%) "GO:0016114 (16%) GO:0019288 (16%) GO:0009228 (15.2%)" GO:0005829 (16%) "GO:0008661 (16%) GO:0046872 (15.2%)" "terpenoid biosynthetic process (16%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (16%) thiamine biosynthetic process (15.2%)" cytosol (16%) "1-deoxy-D-xylulose-5-phosphate synthase activity (16%) metal ion binding (15.2%)" "IPR005475 (17%) IPR005477 (17%) IPR033248 (17%)" "Transketolase-like, pyrimidine-binding domain (17%) Deoxyxylulose-5-phosphate synthase (17%) Transketolase, C-terminal domain (17%)" GVCGVAGGDGTPNSGVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0016485 (32%) GO:0006508 (2%)" GO:0016020 (32%) GO:0004252 (34%) "protein processing (32%) proteolysis (2%)" membrane (32%) serine-type endopeptidase activity (34%) "IPR000209 (16.2%) IPR022398 (16.2%) IPR023828 (16.2%)" "Peptidase S8/S53 domain (16.2%) Peptidase S8, subtilisin, His-active site (16.2%) Peptidase S8, subtilisin, Ser-active site (16.2%)" LEQFLADFDTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (48.9%) GO:0051536 (48.9%) GO:0004355 (2.3%)" "oxidoreductase activity (48.9%) iron-sulfur cluster binding (48.9%) glutamate synthase (NADPH) activity (2.3%)" "IPR023753 (25.6%) IPR028261 (25.6%) IPR009051 (24.4%)" "FAD/NAD(P)-binding domain (25.6%) Dihydroprymidine dehydrogenase domain II (25.6%) Alpha-helical ferredoxin (24.4%)" FASPVSGEVTALER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" ELGHLLWEHVGMGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (18.3%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (18.3%)" "IPR015939 (14.6%) IPR030664 (14.6%) IPR037099 (14.6%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.6%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.6%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (14.6%)" NNELNNLVLPVVVSEEFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" LKPHYAGLGASNTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (63.6%) IPR008160 (36.4%)" "Domain of unknown function DUF4988 (63.6%) Collagen triple helix repeat (36.4%)" NNPVLLGEPGVGK root "3.4.21.92 (83.3%) 3.4.-.- (16.7%)" "endopeptidase Clp (83.3%) Acting on peptide bonds (peptidases) (16.7%)" "GO:0034605 (18%) GO:0042026 (12.6%) GO:0006508 (5.2%)" "GO:0005737 (14.3%) GO:0005829 (3.5%) GO:0009507 (0.4%)" "GO:0005524 (18.2%) GO:0016887 (18.2%) GO:0008233 (5.2%)" "cellular response to heat (18%) protein refolding (12.6%) proteolysis (5.2%)" "cytoplasm (14.3%) cytosol (3.5%) chloroplast (0.4%)" "ATP binding (18.2%) ATP hydrolysis activity (18.2%) peptidase activity (5.2%)" "IPR050130 (8.6%) IPR027417 (8.6%) IPR003959 (8.6%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) P-loop containing nucleoside triphosphate hydrolase (8.6%) ATPase, AAA-type, core (8.6%)" ALYNALFPFAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.9%) "GO:0008236 (33%) GO:0008239 (33%)" proteolysis (33.9%) "serine-type peptidase activity (33%) dipeptidyl-peptidase activity (33%)" "IPR002469 (25.9%) IPR001375 (25.2%) IPR050278 (25.2%)" "Dipeptidylpeptidase IV, N-terminal domain (25.9%) Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Serine protease S9B/DPPIV (25.2%)" LSYLGMK root "7.1.1.2 (67.3%) 3.5.4.16 (16.3%) 3.1.4.- (6.1%)" "NADH:ubiquinone reductase (H(+)-translocating) (67.3%) GTP cyclohydrolase I (16.3%) Phosphoric diester hydrolases (6.1%)" "GO:0044718 (10%) GO:0015990 (3.3%) GO:0042773 (3.3%)" "GO:0009279 (31.7%) GO:0016020 (4.4%) GO:0031966 (3.3%)" "GO:0015344 (10.1%) GO:0008137 (3.5%) GO:0048039 (3.3%)" "siderophore transmembrane transport (10%) electron transport coupled proton transport (3.3%) ATP synthesis coupled electron transport (3.3%)" "cell outer membrane (31.7%) membrane (4.4%) mitochondrial membrane (3.3%)" "siderophore uptake transmembrane transporter activity (10.1%) NADH dehydrogenase (ubiquinone) activity (3.5%) ubiquinone binding (3.3%)" "IPR012910 (11.4%) IPR039426 (11.4%) IPR037066 (11.3%)" "TonB-dependent receptor, plug domain (11.4%) TonB-dependent receptor-like (11.4%) TonB-dependent receptor, plug domain superfamily (11.3%)" LYADSDVFWTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (62.5%) GO:0016787 (37.5%)" "acyltransferase activity, transferring groups other than amino-acyl groups (62.5%) hydrolase activity (37.5%)" "IPR000182 (20.5%) IPR001110 (20.5%) IPR003010 (20.5%)" "GNAT domain (20.5%) Uncharacterised protein family UPF0012, conserved site (20.5%) Carbon-nitrogen hydrolase (20.5%)" GQHVSGGLFAPALSYNKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20%) IPR013320 (20%) IPR023296 (20%)" "Glycoside hydrolase, family 43 (20%) Concanavalin A-like lectin/glucanase domain superfamily (20%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (20%)" SGQTVQGTDVLFPQLGELLGGSVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.3%) GO:0005737 (19.5%) "GO:0005524 (20.3%) GO:0003676 (19.5%) GO:0004816 (19.5%)" asparaginyl-tRNA aminoacylation (20.3%) cytoplasm (19.5%) "ATP binding (20.3%) nucleic acid binding (19.5%) asparagine-tRNA ligase activity (19.5%)" "IPR004364 (15%) IPR004365 (14.4%) IPR004522 (14.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (15%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (14.4%) Asparagine-tRNA ligase (14.4%)" MAQYTEELRDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016747 (55.6%) GO:0016787 (44.4%)" "acyltransferase activity, transferring groups other than amino-acyl groups (55.6%) hydrolase activity (44.4%)" "IPR003010 (22%) IPR000182 (20%) IPR001110 (20%)" "Carbon-nitrogen hydrolase (22%) GNAT domain (20%) Uncharacterised protein family UPF0012, conserved site (20%)" LDLSDLELVDMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.7%) "GO:0016746 (17.4%) GO:0051287 (17.4%) GO:0046872 (16.7%)" malate metabolic process (16.7%) "acyltransferase activity (17.4%) NAD binding (17.4%) metal ion binding (16.7%)" "IPR002505 (9.3%) IPR012302 (9.3%) IPR036291 (9.3%)" "Phosphate acetyl/butaryl transferase (9.3%) Malic enzyme, NAD-binding (9.3%) NAD(P)-binding domain superfamily (9.3%)" NYNLVDDFNVGNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (36%) GO:0009279 (64%) iron ion transport (36%) cell outer membrane (64%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" GELSQWLDPSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20%) IPR002358 (20%) IPR019906 (20%)" "Large ribosomal subunit protein uL6-like (20%) Large ribosomal subunit protein uL6, conserved site (20%) Large ribosomal subunit protein uL6, bacteria (20%)" NLNDGADATWQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016829 (75%) GO:0004557 (25%)" "lyase activity (75%) alpha-galactosidase activity (25%)" "IPR052063 (36.4%) IPR011050 (31.8%) IPR012334 (31.8%)" "Polysaccharide Lyase 1 (36.4%) Pectin lyase fold/virulence factor (31.8%) Pectin lyase fold (31.8%)" SFLDYQDNLYSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.8%) IPR034982 (33.8%) IPR038352 (32.3%)" "Imelysin-like domain (33.8%) Iron-regulated protein A, imelysin-like domain (33.8%) Imelysin-like domain superfamily (32.3%)" DFDEQYTLDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (66.7%) IPR008160 (33.3%)" "Domain of unknown function DUF4988 (66.7%) Collagen triple helix repeat (33.3%)" SLYACYDGWQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" QLAEEGLVLLQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" NATGYDHNWCLNTYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.1.3.3 (94.9%) 5.1.3.- (5.1%)" "aldose 1-epimerase (94.9%) Acting on carbohydrates and derivatives (5.1%)" "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19.2%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19.2%)" "IPR008183 (17.1%) IPR018052 (17.1%) IPR047215 (17.1%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.1%) Aldose 1-epimerase, conserved site (17.1%) Galactose mutarotase-like (17.1%)" FATSDLNDLYR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (16.5%) GO:0006281 (0%) GO:0006412 (0%)" "GO:0000428 (16.6%) GO:0005829 (3.3%) GO:0009507 (0%)" "GO:0003677 (16.5%) GO:0003899 (16.5%) GO:0000287 (14.7%)" "DNA-templated transcription (16.5%) DNA repair (0%) translation (0%)" "DNA-directed RNA polymerase complex (16.6%) cytosol (3.3%) chloroplast (0%)" "DNA binding (16.5%) DNA-directed RNA polymerase activity (16.5%) magnesium ion binding (14.7%)" "IPR007080 (9.6%) IPR045867 (9.6%) IPR006592 (9.4%)" "RNA polymerase Rpb1, domain 1 (9.6%) DNA-directed RNA polymerase, subunit beta-prime (9.6%) RNA polymerase, N-terminal (9.4%)" VLPMDLYGEYLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "7.2.1.1 (98.9%) 1.6.5.- (1.1%)" "NADH:ubiquinone reductase (Na(+)-transporting) (98.9%) With a quinone or similar compound as acceptor (1.1%)" GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (22.5%) IPR022615 (22.3%) IPR056148 (22.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (22.5%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (22.3%) NqrA, second alpha/beta domain (22.3%)" GLAPLELEFLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR011990 (100%) Tetratricopeptide-like helical domain superfamily (100%) SLPPDVLLEQTPVFGEVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR005543 (100%) PASTA domain (100%) GYSALVVYDDLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (18.4%) GO:0005886 (18.1%)" "GO:0005524 (18.4%) GO:0043531 (18.4%) GO:0046933 (18.4%)" "proton-transporting ATP synthase complex (18.4%) plasma membrane (18.1%)" "ATP binding (18.4%) ADP binding (18.4%) proton-transporting ATP synthase activity, rotational mechanism (18.4%)" "IPR000194 (10.1%) IPR005294 (10.1%) IPR027417 (10.1%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.1%) ATP synthase, F1 complex, alpha subunit (10.1%) P-loop containing nucleoside triphosphate hydrolase (10.1%)" GFSNETLQNLHEAYR Pseudomonadati Bacteria Pseudomonadati 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (31.4%) GO:0008610 (2.9%)" GO:0016020 (31.4%) GO:0008780 (34.3%) "lipid A biosynthetic process (31.4%) lipid biosynthetic process (2.9%)" membrane (31.4%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.3%) "IPR010137 (20.7%) IPR011004 (20.7%) IPR029098 (20.7%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.7%) Trimeric LpxA-like superfamily (20.7%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.7%)" ASLKESYDFVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR033985 (36.4%) IPR011990 (27.3%)" "RagB/SusD domain (36.4%) SusD-like, N-terminal (36.4%) Tetratricopeptide-like helical domain superfamily (27.3%)" TYQVVNLLQLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (20.5%) GO:0006221 (20.5%)" GO:0009347 (20.5%) "GO:0046872 (20.5%) GO:0016740 (17.9%)" "'de novo' pyrimidine nucleobase biosynthetic process (20.5%) pyrimidine nucleotide biosynthetic process (20.5%)" aspartate carbamoyltransferase complex (20.5%) "metal ion binding (20.5%) transferase activity (17.9%)" "IPR002801 (21.1%) IPR020542 (21.1%) IPR020545 (21.1%)" "Aspartate transcarbamylase regulatory subunit (21.1%) Aspartate carbamoyltransferase regulatory subunit, C-terminal (21.1%) Aspartate carbamoyltransferase regulatory subunit, N-terminal (21.1%)" LLNNTVTLK root GO:0005975 (100%) carbohydrate metabolic process (100%) "IPR032283 (33.3%) IPR038081 (30.9%) IPR032299 (29.6%)" "Domain of unknown function DUF4984 (33.3%) CalX-like domain superfamily (30.9%) Protein of unknown function DUF4843 (29.6%)" FLQAGLMK root "3.1.-.- (50%) 3.6.4.- (50%)" "Acting on ester bonds (50%) Acting on ATP; involved in cellular and subcellular movement (50%)" "GO:0044341 (28.2%) GO:0006298 (1.5%) GO:0045910 (1.5%)" GO:0005886 (28.2%) "GO:0005436 (28.2%) GO:0004519 (1.5%) GO:0005524 (1.5%)" "sodium-dependent phosphate transport (28.2%) mismatch repair (1.5%) negative regulation of DNA recombination (1.5%)" plasma membrane (28.2%) "sodium:phosphate symporter activity (28.2%) endonuclease activity (1.5%) ATP binding (1.5%)" "IPR003841 (24.7%) IPR038078 (24%) IPR026022 (21.3%)" "Sodium-dependent phosphate transport protein (24.7%) PhoU-like domain superfamily (24%) PhoU domain (21.3%)" SVTGFDLYSALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006281 (25%) GO:0006310 (25%)" "GO:0003676 (25%) GO:0008409 (25%)" "DNA repair (25%) DNA recombination (25%)" "nucleic acid binding (25%) 5'-3' exonuclease activity (25%)" "IPR001667 (17.1%) IPR003156 (17.1%) IPR004610 (17.1%)" "DDH domain (17.1%) DHHA1 domain (17.1%) Bacterial RecJ exonuclease (17.1%)" EFAAQTMDEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" EGEECFLDEHLGFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.65 (100%) phosphatidylserine decarboxylase (100%) "GO:0006646 (31.4%) GO:0008654 (2%)" GO:0005886 (33.3%) GO:0004609 (33.3%) "phosphatidylethanolamine biosynthetic process (31.4%) phospholipid biosynthetic process (2%)" plasma membrane (33.3%) phosphatidylserine decarboxylase activity (33.3%) "IPR003817 (50%) IPR033175 (50%)" "Phosphatidylserine decarboxylase-related (50%) Phosphatidylserine decarboxylase, prokaryotes (50%)" SYTYYYSVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.9%) IPR003385 (20.9%) IPR013783 (19.4%)" "Carbohydrate binding module family 20 (20.9%) Glycoside hydrolase, family 77 (20.9%) Immunoglobulin-like fold (19.4%)" FNLGAQYCYGER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DGECTEYNFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (29.6%) IPR014756 (29.6%) IPR040475 (29.6%)" "Immunoglobulin-like fold (29.6%) Immunoglobulin E-set (29.6%) Surface glycan-binding protein B, xyloglucan binding domain (29.6%)" LVVNGYADSATGSAALNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (27.3%) IPR050330 (27.3%) IPR011250 (22.7%)" "OmpA-like domain (27.3%) Bacterial Outer Membrane Structural/Functional (27.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (22.7%)" LDGHLVQGHVDETAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.9 (100%) riboflavin synthase (100%) GO:0009231 (50%) GO:0004746 (50%) riboflavin biosynthetic process (50%) riboflavin synthase activity (50%) "IPR001783 (25.8%) IPR026017 (25.8%) IPR017938 (24.2%)" "Lumazine-binding protein (25.8%) Lumazine-binding domain (25.8%) Riboflavin synthase-like beta-barrel (24.2%)" AGLAELVQAMCYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.4 (100%) tripeptide aminopeptidase (100%) "GO:0006508 (16.7%) GO:0043171 (16.5%) GO:0006518 (0.2%)" GO:0005829 (16.7%) "GO:0008237 (16.7%) GO:0008270 (16.7%) GO:0045148 (16.7%)" "proteolysis (16.7%) peptide catabolic process (16.5%) peptide metabolic process (0.2%)" cytosol (16.7%) "metallopeptidase activity (16.7%) zinc ion binding (16.7%) tripeptide aminopeptidase activity (16.7%)" "IPR001261 (20.2%) IPR002933 (20.2%) IPR010161 (20.2%)" "ArgE/DapE/ACY1/CPG2/YscS, conserved site (20.2%) Peptidase M20 (20.2%) Peptidase M20B, tripeptide aminopeptidase (20.2%)" VPAAWQGYTAEQMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (44%) "GO:0015926 (44%) GO:0031218 (12%)" pectin catabolic process (44%) "glucosidase activity (44%) arabinogalactan endo-1,4-beta-galactosidase activity (12%)" "IPR011683 (50%) IPR017853 (50%)" "Glycosyl hydrolase family 53 (50%) Glycoside hydrolase superfamily (50%)" ADAEVLDAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.8%) GO:0033711 (2.2%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.8%) 4-phosphoerythronate dehydrogenase activity (2.2%)" "IPR006139 (31.1%) IPR006140 (31.1%) IPR036291 (31.1%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (31.1%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (31.1%) NAD(P)-binding domain superfamily (31.1%)" VVVPDAFFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.1.30.- (97.6%) 3.-.-.- (2.4%)" "Endoribonucleases active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters (97.6%) Hydrolases (2.4%)" "GO:0003676 (25%) GO:0004519 (25%) GO:0016787 (25%)" "nucleic acid binding (25%) endonuclease activity (25%) hydrolase activity (25%)" "IPR001604 (16.8%) IPR018524 (16.8%) IPR020821 (16.8%)" "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase domain (16.8%) DNA/RNA non-specific endonuclease, active site (16.8%) ENPP1-3/EXOG-like, endonuclease/phosphodiesterase domain (16.8%)" NLTDNALAYAGEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0016036 (20.4%) GO:0005886 (20.4%) "GO:0000155 (20.4%) GO:0004721 (20.4%) GO:0005524 (18.5%)" cellular response to phosphate starvation (20.4%) plasma membrane (20.4%) "phosphorelay sensor kinase activity (20.4%) phosphoprotein phosphatase activity (20.4%) ATP binding (18.5%)" "IPR003594 (14.7%) IPR003661 (14.7%) IPR005467 (14.7%)" "Histidine kinase/HSP90-like ATPase domain (14.7%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (14.7%) Histidine kinase domain (14.7%)" NFASQYNGNPYAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016747 (50%) GO:0016788 (46.8%) GO:0016787 (3.2%)" "acyltransferase activity, transferring groups other than amino-acyl groups (50%) hydrolase activity, acting on ester bonds (46.8%) hydrolase activity (3.2%)" "IPR000801 (17.2%) IPR005181 (17.2%) IPR050583 (17.2%)" "Esterase-like (17.2%) Sialate O-acetylesterase domain (17.2%) Mycobacterial A85 antigen (17.2%)" LANAYEFLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (22.9%) GO:0016020 (2.1%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (22.9%) membrane (2.1%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.6%) IPR003593 (14.6%) IPR011527 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) AAA+ ATPase domain (14.6%) ABC transporter type 1, transmembrane domain (14.6%)" EVVFQHYENR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.4%) IPR024742 (20.4%) IPR032790 (20.4%)" "Glycogen debranching enzyme (20.4%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.4%) Glycogen debranching enzyme, C-terminal (20.4%)" TNPQAYVLTKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030246 (50.8%) GO:0016787 (49.2%)" "carbohydrate binding (50.8%) hydrolase activity (49.2%)" "IPR019563 (14.5%) IPR029483 (14.5%) IPR029486 (14.5%)" "Glycosyl-hydrolase 97, catalytic domain (14.5%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.5%) Glycosyl-hydrolase 97, N-terminal domain (14.5%)" YLLSSGGAPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.37 (44.4%) 1.1.1.40 (38.9%) 1.1.1.- (16.7%)" "malate dehydrogenase (44.4%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (38.9%) With NAD(+) or NADP(+) as acceptor (16.7%)" "GO:0006108 (32.3%) GO:0006089 (3.4%)" GO:0016020 (0.3%) "GO:0016615 (28.3%) GO:0016616 (28.3%) GO:0004459 (3.4%)" "malate metabolic process (32.3%) lactate metabolic process (3.4%)" membrane (0.3%) "malate dehydrogenase activity (28.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (28.3%) L-lactate dehydrogenase (NAD+) activity (3.4%)" "IPR001236 (16.9%) IPR001557 (16.9%) IPR015955 (16.9%)" "Lactate/malate dehydrogenase, N-terminal (16.9%) L-lactate/malate dehydrogenase (16.9%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.9%)" SAGYDVGLAGNLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.2.9 (100%) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase (100%) "GO:0008360 (14.4%) GO:0009252 (14.4%) GO:0051301 (14.4%)" GO:0005737 (14.4%) "GO:0005524 (14.4%) GO:0008764 (14.4%)" "regulation of cell shape (14.4%) peptidoglycan biosynthetic process (14.4%) cell division (14.4%)" cytoplasm (14.4%) "ATP binding (14.4%) UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (14.4%)" "IPR005762 (20.6%) IPR013221 (20.6%) IPR036565 (20%)" "UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD (20.6%) Mur ligase, central (20.6%) Mur-like, catalytic domain superfamily (20%)" DGHDEASGLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR007298 (100%) Copper resistance lipoprotein NlpE (100%) GEFLNSAQFSPDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (34.2%) IPR011042 (33.3%) IPR029058 (32.4%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.2%) Six-bladed beta-propeller, TolB-like (33.3%) Alpha/Beta hydrolase fold (32.4%)" LNDAFFADPASVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" ALLEQELEQQRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" LVNDPEHPVLFFFSGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (90.9%) 2.4.1.8 (9.1%)" "glycogen phosphorylase (90.9%) maltose phosphorylase (9.1%)" GO:0005975 (33.1%) "GO:0030170 (33.1%) GO:0008184 (32.6%) GO:0004645 (0.6%)" carbohydrate metabolic process (33.1%) "pyridoxal phosphate binding (33.1%) glycogen phosphorylase activity (32.6%) 1,4-alpha-oligoglucan phosphorylase activity (0.6%)" "IPR011834 (25.2%) IPR052182 (25.2%) IPR000811 (24.8%)" "Alpha-glucan phosphorylase (25.2%) Glycogen_Maltodextrin_Phosphorylase (25.2%) Glycosyl transferase, family 35 (24.8%)" ALYWVETGAQPTDTVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005737 (25%) GO:0015935 (25%)" GO:0003735 (25%) translation (25%) "cytoplasm (25%) small ribosomal subunit (25%)" structural constituent of ribosome (25%) "IPR000307 (50%) IPR023803 (50%)" "Small ribosomal subunit protein bS16 (50%) Small ribosomal subunit protein bS16 domain superfamily (50%)" GKTEQLANYFSEYALLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (19.6%) GO:0044208 (19.6%) GO:0006188 (17.4%)" "GO:0004018 (37%) GO:0070626 (4.3%) GO:0016829 (2.2%)" "'de novo' IMP biosynthetic process (19.6%) 'de novo' AMP biosynthetic process (19.6%) IMP biosynthetic process (17.4%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (37%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (4.3%) lyase activity (2.2%)" "IPR008948 (12.9%) IPR022761 (12.9%) IPR024083 (12.9%)" "L-Aspartase-like (12.9%) Fumarate lyase, N-terminal (12.9%) Fumarase/histidase, N-terminal (12.9%)" EAEAMPYTVVNEGGYPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (33.9%) GO:0140662 (33.9%) GO:0051082 (32.3%)" "ATP binding (33.9%) ATP-dependent protein folding chaperone (33.9%) unfolded protein binding (32.3%)" "IPR013126 (17.1%) IPR018181 (17.1%) IPR043129 (17.1%)" "Heat shock protein 70 family (17.1%) Heat shock protein 70, conserved site (17.1%) ATPase, nucleotide binding domain (17.1%)" KLEGFDFK root 4.1.3.36 (100%) 1,4-dihydroxy-2-naphthoyl-CoA synthase (100%) "GO:0009234 (29.6%) GO:0036444 (1.4%) GO:0051560 (1.4%)" "GO:0005829 (29.6%) GO:1990246 (1.4%)" "GO:0008935 (29.6%) GO:0003723 (1.4%) GO:0005262 (1.4%)" "menaquinone biosynthetic process (29.6%) calcium import into the mitochondrion (1.4%) mitochondrial calcium ion homeostasis (1.4%)" "cytosol (29.6%) uniplex complex (1.4%)" "1,4-dihydroxy-2-naphthoyl-CoA synthase activity (29.6%) RNA binding (1.4%) calcium channel activity (1.4%)" "IPR001753 (16.7%) IPR010198 (16.7%) IPR014748 (16.7%)" "Enoyl-CoA hydratase/isomerase (16.7%) 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB (16.7%) Enoyl-CoA hydratase, C-terminal (16.7%)" LTDLMFAGTDDQLKETK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.39 (100%) [acyl-carrier-protein] S-malonyltransferase (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004314 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) [acyl-carrier-protein] S-malonyltransferase activity (33.3%) "IPR014043 (15.4%) IPR050858 (15.4%) IPR004410 (14.7%)" "Acyl transferase domain (15.4%) Malonyl CoA-ACP Transacylase/Polyketide Synthase FabD (15.4%) Malonyl CoA-acyl carrier protein transacylase, FabD-type (14.7%)" NPHYVTLESAGAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.3%) GO:0046556 (50.7%) L-arabinose metabolic process (49.3%) alpha-L-arabinofuranosidase activity (50.7%) "IPR003305 (17.4%) IPR051563 (17.4%) IPR010720 (16.9%)" "Carbohydrate-binding, CenC-like (17.4%) Glycosyl Hydrolase Family 51 (17.4%) Alpha-L-arabinofuranosidase, C-terminal (16.9%)" VTLTDGSFHPVDSDQLSFELVAHQAFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20.1%) GO:0005737 (19.8%) "GO:0003746 (20.1%) GO:0005525 (20.1%) GO:0003924 (19.8%)" ribosome disassembly (20.1%) cytoplasm (19.8%) "translation elongation factor activity (20.1%) GTP binding (20.1%) GTPase activity (19.8%)" "IPR000640 (6.3%) IPR004161 (6.3%) IPR005517 (6.3%)" "Elongation factor EFG, domain V-like (6.3%) Translation elongation factor EFTu-like, domain 2 (6.3%) Translation elongation factor EFG/EF2, domain IV (6.3%)" LATPDPMVTVGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) GO:0005737 (25%) "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) cytoplasm (25%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR028923 (50.2%) IPR018236 (49.8%)" "SAICAR synthetase/ADE2, N-terminal (50.2%) SAICAR synthetase, conserved site (49.8%)" VNLVRDETGFPLSFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" LPAFATDR root "1.3.1.76 (33.3%) 2.7.13.3 (33.3%) 3.4.19.12 (33.3%)" "precorrin-2 dehydrogenase (33.3%) histidine kinase (33.3%) ubiquitinyl hydrolase 1 (33.3%)" "GO:0017038 (18.2%) GO:0051301 (18.2%) GO:0006508 (2%)" "GO:0042597 (18.2%) GO:0005829 (4%) GO:0005886 (2%)" "GO:0004601 (4%) GO:0020037 (4%) GO:0046872 (4%)" "protein import (18.2%) cell division (18.2%) proteolysis (2%)" "periplasmic space (18.2%) cytosol (4%) plasma membrane (2%)" "peroxidase activity (4%) heme binding (4%) metal ion binding (4%)" "IPR007195 (8.7%) IPR011042 (8.7%) IPR011659 (8.7%)" "TolB, N-terminal (8.7%) Six-bladed beta-propeller, TolB-like (8.7%) WD40-like beta-propeller (8.7%)" AHLVGDFLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (26%) IPR025997 (26%) IPR010982 (24%)" "LacI-type HTH domain (26%) Periplasmic binding protein (26%) Lambda repressor-like, DNA-binding domain superfamily (24%)" FLCTVCGYLYEGTEAPEKCPLCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005506 (50%) GO:0004601 (42.3%) GO:0016491 (7.7%)" "iron ion binding (50%) peroxidase activity (42.3%) oxidoreductase activity (7.7%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" NPFAQFLK root GO:0009279 (100%) cell outer membrane (100%) "IPR000184 (50%) IPR039910 (50%)" "Bacterial surface antigen (D15) (50%) Surface antigen D15-like (50%)" MAQTSCFANETTGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (33.3%) "GO:0004556 (33.3%) GO:0043169 (33.3%)" carbohydrate metabolic process (33.3%) "alpha-amylase activity (33.3%) cation binding (33.3%)" "IPR006046 (33.3%) IPR006047 (33.3%) IPR017853 (33.3%)" "Alpha amylase (33.3%) Glycosyl hydrolase family 13, catalytic domain (33.3%) Glycoside hydrolase superfamily (33.3%)" LLLTSHNPDMVSALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005524 (100%) ATP binding (100%) "IPR041685 (33.9%) IPR051396 (33.9%) IPR027417 (32.1%)" "Endonuclease GajA/Old nuclease/RecF-like, AAA domain (33.9%) Bacterial Antiviral Defense Nuclease (33.9%) P-loop containing nucleoside triphosphate hydrolase (32.1%)" FNEWAAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" ATWNKVPDVDALNALHQSELDALNAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (3.7%) GO:0016020 (92.6%) GO:0008233 (3.7%) proteolysis (3.7%) membrane (92.6%) peptidase activity (3.7%) "IPR006665 (27.2%) IPR050330 (27.2%) IPR036737 (25%)" "OmpA-like domain (27.2%) Bacterial Outer Membrane Structural/Functional (27.2%) OmpA-like domain superfamily (25%)" TMFLLNAPTAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50%) "GO:0016798 (35.9%) GO:0051060 (14.1%)" carbohydrate metabolic process (50%) "hydrolase activity, acting on glycosyl bonds (35.9%) pullulanase activity (14.1%)" "IPR006047 (14.7%) IPR011840 (14.7%) IPR049117 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (14.7%) Pullulanase, type I (14.7%) Pullulanase, all-beta domain (14.7%)" LGNVYGLMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0004019 (16.7%) GO:0005525 (16.7%) GO:0000287 (16.4%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "adenylosuccinate synthase activity (16.7%) GTP binding (16.7%) magnesium ion binding (16.4%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" YNLSFSEQKPSTDTLAANPDNTPFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016301 (100%) kinase activity (100%) "IPR025393 (51.6%) IPR029044 (48.4%)" "Domain of unknown function DUF4301 (51.6%) Nucleotide-diphospho-sugar transferases (48.4%)" LFVYTEAMNQGLTPCDKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.-.- (20%) 2.4.1.- (20%) 2.4.1.129 (20%)" "Glycosyltransferases (20%) Hexosyltransferases (20%) Transferred entry: 2.4.99.28 (20%)" "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.7%) GO:0016020 (0.5%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.7%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.7%) membrane (0.5%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.7%)" "IPR001460 (17.1%) IPR050396 (17.1%) IPR001264 (16.9%)" "Penicillin-binding protein, transpeptidase (17.1%) Glycosyltransferase 51/Transpeptidase (17.1%) Glycosyl transferase, family 51 (16.9%)" MFQLYGFSADEAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" ETVAAGDWAALTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (63.6%) GO:0008675 (18.2%) GO:0008700 (18.2%)" "lyase activity (63.6%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (18.2%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (18.2%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" VLDAALEASK root 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.3%) GO:0046040 (16.3%) GO:0006417 (0.6%)" "GO:0005737 (16.3%) GO:0005829 (0.6%)" "GO:0000287 (16.3%) GO:0004019 (16.3%) GO:0005525 (16.3%)" "'de novo' AMP biosynthetic process (16.3%) IMP metabolic process (16.3%) regulation of translation (0.6%)" "cytoplasm (16.3%) cytosol (0.6%)" "magnesium ion binding (16.3%) adenylosuccinate synthase activity (16.3%) GTP binding (16.3%)" "IPR001114 (13.9%) IPR018220 (13.9%) IPR027417 (13.9%)" "Adenylosuccinate synthetase (13.9%) Adenylosuccinate synthase, GTP-binding site (13.9%) P-loop containing nucleoside triphosphate hydrolase (13.9%)" VNSLAENNPMLGHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" KMTYDLNYLELPAVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025665 (88%) IPR036709 (12%)" "Outer membrane protein, beta-barrel domain 2 (88%) Autotransporter beta-domain superfamily (12%)" SLMQLAEDLGMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (17.1%) GO:0009098 (17.1%) GO:0009099 (17.1%)" "GO:0004084 (17.4%) GO:0052654 (6.1%) GO:0052655 (6.1%)" "isoleucine biosynthetic process (17.1%) L-leucine biosynthetic process (17.1%) L-valine biosynthetic process (17.1%)" "branched-chain-amino-acid transaminase activity (17.4%) L-leucine-2-oxoglutarate transaminase activity (6.1%) L-valine-2-oxoglutarate transaminase activity (6.1%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" YGTEPDGYVNYVK Bacteroidota Bacteria Pseudomonadati Bacteroidota "1.4.1.4 (90.9%) 1.4.1.3 (9.1%)" "glutamate dehydrogenase (NADP(+)) (90.9%) glutamate dehydrogenase [NAD(P)(+)] (9.1%)" GO:0006537 (26.6%) GO:0005829 (26.6%) "GO:0004354 (26.6%) GO:0000166 (20.2%)" glutamate biosynthetic process (26.6%) cytosol (26.6%) "glutamate dehydrogenase (NADP+) activity (26.6%) nucleotide binding (20.2%)" "IPR006096 (11.5%) IPR036291 (11.5%) IPR050724 (11.5%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.5%) NAD(P)-binding domain superfamily (11.5%) Glutamate/Leucine/Phenylalanine/Valine dehydrogenases (11.5%)" LPALTETGCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.78 (100%) mannan endo-1,4-beta-mannosidase (100%) GO:0006080 (37.6%) GO:0005576 (24.8%) GO:0016985 (37.6%) substituted mannan metabolic process (37.6%) extracellular region (24.8%) mannan endo-1,4-beta-mannosidase activity (37.6%) "IPR000805 (25.9%) IPR022790 (25.9%) IPR017853 (24.5%)" "Glycoside hydrolase family 26 (25.9%) Glycosyl hydrolase family 26 domain (25.9%) Glycoside hydrolase superfamily (24.5%)" KLTLTQFGYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (22.3%) IPR052595 (22.3%) IPR013783 (21.3%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (22.3%) Leucine-rich repeat-containing protein 69/Receptor-like (22.3%) Immunoglobulin-like fold (21.3%)" TSYLLDR root "6.3.5.3 (77.8%) 6.1.1.3 (12.6%) 2.7.1.150 (1.1%)" "phosphoribosylformylglycinamidine synthase (77.8%) threonine--tRNA ligase (12.6%) 1-phosphatidylinositol-3-phosphate 5-kinase (1.1%)" "GO:0006189 (12.6%) GO:0006435 (1.7%) GO:0051301 (0.4%)" "GO:0005737 (13.7%) GO:0016020 (2.1%) GO:0005829 (1.9%)" "GO:0005524 (15.2%) GO:0046872 (14.8%) GO:0004642 (13%)" "'de novo' IMP biosynthetic process (12.6%) threonyl-tRNA aminoacylation (1.7%) cell division (0.4%)" "cytoplasm (13.7%) membrane (2.1%) cytosol (1.9%)" "ATP binding (15.2%) metal ion binding (14.8%) phosphoribosylformylglycinamidine synthase activity (13%)" "IPR010918 (7.2%) IPR055181 (7.2%) IPR029062 (7.1%)" "PurM-like, C-terminal domain (7.2%) FGAR-AT, PurM N-terminal-like domain (7.2%) Class I glutamine amidotransferase-like (7.1%)" FNNEDYYWTMGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (27.3%) IPR013780 (26.3%) IPR017853 (26.3%)" "Alpha-L-arabinofuranosidase, C-terminal (27.3%) Glycosyl hydrolase, all-beta (26.3%) Glycoside hydrolase superfamily (26.3%)" HVSVCFESQKYPDSPTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.1.3.3 (93.9%) 5.1.3.- (6.1%)" "aldose 1-epimerase (93.9%) Acting on carbohydrates and derivatives (6.1%)" "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19%)" "IPR008183 (17.2%) IPR018052 (17.2%) IPR047215 (17.2%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.2%) Aldose 1-epimerase, conserved site (17.2%) Galactose mutarotase-like (17.2%)" NFMAGFLTGTTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" LSLLPPLR root "1.4.1.13 (23%) 1.14.14.1 (20.7%) 1.6.2.4 (20.7%)" "glutamate synthase (NADPH) (23%) unspecific monooxygenase (20.7%) NADPH--hemoprotein reductase (20.7%)" "GO:0007189 (2.8%) GO:0038035 (2.3%) GO:0050850 (2.3%)" "GO:0005886 (6.9%) GO:0043235 (5.6%) GO:0010008 (5%)" "GO:0004930 (6%) GO:0005524 (2.7%) GO:0008270 (2.4%)" "adenylate cyclase-activating G protein-coupled receptor signaling pathway (2.8%) ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway (2.3%) positive regulation of calcium-mediated signaling (2.3%)" "plasma membrane (6.9%) receptor complex (5.6%) endosome membrane (5%)" "G protein-coupled receptor activity (6%) ATP binding (2.7%) zinc ion binding (2.4%)" "IPR000276 (5.9%) IPR017452 (5.7%) IPR003796 (2.1%)" "G protein-coupled receptor, rhodopsin-like (5.9%) GPCR, rhodopsin-like, 7TM (5.7%) Ribonucleotide reductase regulator NrdR-like (2.1%)" NLAQMLK root "4.3.3.6 (89.7%) 1.5.1.2 (3.1%) 1.8.1.4 (2.4%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (89.7%) pyrroline-5-carboxylate reductase (3.1%) dihydrolipoyl dehydrogenase (2.4%)" "GO:0006520 (20.2%) GO:0042823 (20.2%) GO:0008615 (20.1%)" "GO:0005737 (1.5%) GO:0005886 (0.5%) GO:0045252 (0.5%)" "GO:0036381 (19.9%) GO:0004735 (0.7%) GO:0004148 (0.5%)" "amino acid metabolic process (20.2%) pyridoxal phosphate biosynthetic process (20.2%) pyridoxine biosynthetic process (20.1%)" "cytoplasm (1.5%) plasma membrane (0.5%) oxoglutarate dehydrogenase complex (0.5%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (19.9%) pyrroline-5-carboxylate reductase activity (0.7%) dihydrolipoyl dehydrogenase (NADH) activity (0.5%)" "IPR013785 (19.4%) IPR001852 (19.2%) IPR033755 (19.2%)" "Aldolase-type TIM barrel (19.4%) Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (19.2%) PdxS/SNZ N-terminal domain (19.2%)" YDLKPVETAQQGWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0008233 (50%) proteolysis (50%) peptidase activity (50%) "IPR001539 (48.6%) IPR051454 (48.6%) IPR036237 (2.9%)" "Peptidase U32 (48.6%) RNA and ubiquinone modification enzymes (48.6%) Xylose isomerase-like superfamily (2.9%)" VLAVLPER root "2.7.13.3 (40%) 2.1.1.132 (20%) 2.8.4.5 (20%)" "histidine kinase (40%) precorrin-6B C(5,15)-methyltransferase (decarboxylating) (20%) tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase (20%)" "GO:0006508 (2.7%) GO:0009609 (2.7%) GO:0009610 (2.7%)" "GO:0016020 (8.8%) GO:0005886 (8.2%) GO:0005737 (4.1%)" "GO:0015171 (3.4%) GO:0046872 (3.4%) GO:0004252 (2.7%)" "proteolysis (2.7%) response to symbiotic bacterium (2.7%) response to symbiotic fungus (2.7%)" "membrane (8.8%) plasma membrane (8.2%) cytoplasm (4.1%)" "amino acid transmembrane transporter activity (3.4%) metal ion binding (3.4%) serine-type endopeptidase activity (2.7%)" "IPR021474 (11.5%) IPR001123 (1.9%) IPR000209 (1.5%)" "Protein of unknown function DUF3127 (11.5%) Amino acid exporter protein, LeuE-type (1.9%) Peptidase S8/S53 domain (1.5%)" VNPEYSEVGTLLYNPCAPGTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.96 (100%) carboxynorspermidine decarboxylase (100%) "GO:0009089 (25.2%) GO:0008295 (24.3%) GO:0045312 (24.3%)" GO:0016020 (1%) GO:0008836 (25.2%) "lysine biosynthetic process via diaminopimelate (25.2%) spermidine biosynthetic process (24.3%) nor-spermidine biosynthetic process (24.3%)" membrane (1%) diaminopimelate decarboxylase activity (25.2%) "IPR005730 (25.5%) IPR022643 (25.5%) IPR029066 (24.5%)" "Carboxynorspermidine decarboxylase (25.5%) Orn/DAP/Arg decarboxylase 2, C-terminal (25.5%) PLP-binding barrel (24.5%)" VLFFSDGYLTEDGTPEQLFNHPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25.4%) "GO:0005524 (25.4%) GO:0016887 (25.4%) GO:0015424 (23.9%)" plasma membrane (25.4%) "ATP binding (25.4%) ATP hydrolysis activity (25.4%) ABC-type amino acid transporter activity (23.9%)" "IPR003439 (17%) IPR003593 (17%) IPR017871 (17%)" "ABC transporter-like, ATP-binding domain (17%) AAA+ ATPase domain (17%) ABC transporter-like, conserved site (17%)" LLLFDSSVR root GO:0032259 (1.2%) GO:0016020 (49.4%) "GO:0004467 (48.2%) GO:0008168 (1.2%)" methylation (1.2%) membrane (49.4%) "long-chain fatty acid-CoA ligase activity (48.2%) methyltransferase activity (1.2%)" "IPR000873 (32.8%) IPR020845 (32.8%) IPR042099 (31.1%)" "AMP-dependent synthetase/ligase domain (32.8%) AMP-binding, conserved site (32.8%) ANL, N-terminal domain (31.1%)" DLVDGAPSTLK Bacteria Bacteria GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20.1%) IPR013823 (20.1%) IPR014719 (20.1%)" "Large ribosomal subunit protein bL12 (20.1%) Large ribosomal subunit protein bL12, C-terminal (20.1%) Ribosomal protein bL12, C-terminal/adaptor protein ClpS-like (20.1%)" WTMLSGVAR root GO:0006826 (16.1%) "GO:0009279 (64.5%) GO:0005576 (9.7%) GO:0045202 (9.7%)" iron ion transport (16.1%) "cell outer membrane (64.5%) extracellular region (9.7%) synapse (9.7%)" "IPR012910 (12.2%) IPR023996 (12.2%) IPR023997 (12.2%)" "TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.2%)" EMLLAGLQPNFWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.2%) GO:0009341 (25.2%) "GO:0004565 (25.2%) GO:0030246 (24.3%)" lactose catabolic process (25.2%) beta-galactosidase complex (25.2%) "beta-galactosidase activity (25.2%) carbohydrate binding (24.3%)" "IPR004199 (6.9%) IPR006102 (6.9%) IPR006103 (6.9%)" "Beta galactosidase small chain/ domain 5 (6.9%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.9%) Glycoside hydrolase family 2, catalytic domain (6.9%)" GYVFADAASQTPNA Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015031 (50%) GO:0005886 (50%) protein transport (50%) plasma membrane (50%) IPR003849 (100%) Preprotein translocase YajC (100%) EEGLDKLVEAAGFELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.4%) IPR004430 (14.4%) IPR018136 (14.4%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.4%) 3-isopropylmalate dehydratase, large subunit (14.4%) Aconitase family, 4Fe-4S cluster binding site (14.4%)" TANYAMTLGYMNQEGLVGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" LYLNSEVYTGVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VAGVTGMGGAGFPTFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.-.-.- (100%) Translocases (100%) GO:0022900 (19.4%) "GO:0005886 (19.4%) GO:0016020 (0.6%)" "GO:0009055 (20%) GO:0046872 (20%) GO:0051539 (20%)" electron transport chain (19.4%) "plasma membrane (19.4%) membrane (0.6%)" "electron transfer activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR010208 (14.7%) IPR011538 (14.7%) IPR017896 (14.2%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.7%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.7%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.2%)" VSDPHEVVSLDQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (25%) IPR050437 (25%) IPR012340 (24.1%)" "S1 domain (25%) Small ribosomal subunit protein bS1-like (25%) Nucleic acid-binding, OB-fold (24.1%)" VTLPLLR root "3.5.3.11 (76.4%) 2.7.13.3 (6.8%) 3.5.1.94 (3.2%)" "agmatinase (76.4%) histidine kinase (6.8%) gamma-glutamyl-gamma-aminobutyrate hydrolase (3.2%)" "GO:0055085 (12.7%) GO:0033389 (8.7%) GO:0008295 (7.6%)" "GO:0005886 (16.9%) GO:0016020 (2.1%) GO:0005737 (0.8%)" "GO:0008783 (8.7%) GO:0030145 (6.2%) GO:0046872 (2.8%)" "transmembrane transport (12.7%) putrescine biosynthetic process from arginine, via agmatine (8.7%) spermidine biosynthetic process (7.6%)" "plasma membrane (16.9%) membrane (2.1%) cytoplasm (0.8%)" "agmatinase activity (8.7%) manganese ion binding (6.2%) metal ion binding (2.8%)" "IPR000515 (10.1%) IPR035906 (10.1%) IPR006035 (6.8%)" "ABC transporter type 1, transmembrane domain MetI-like (10.1%) MetI-like superfamily (10.1%) Ureohydrolase (6.8%)" VLVHVDEGNNLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (41.7%) "GO:0015926 (41.7%) GO:0031218 (16.7%)" pectin catabolic process (41.7%) "glucosidase activity (41.7%) arabinogalactan endo-1,4-beta-galactosidase activity (16.7%)" "IPR011683 (50%) IPR017853 (50%)" "Glycosyl hydrolase family 53 (50%) Glycoside hydrolase superfamily (50%)" NEDGSYNTSASFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" HLLEYDDVMNR Pseudomonadati Bacteria Pseudomonadati 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.9%) GO:0017038 (11.9%) GO:0043952 (11.9%)" "GO:0005886 (11.9%) GO:0031522 (11.9%) GO:0005829 (11.8%)" "GO:0005524 (11.9%) GO:0046872 (4.6%) GO:0008564 (0.5%)" "protein targeting (11.9%) protein import (11.9%) protein transport by the Sec complex (11.9%)" "plasma membrane (11.9%) cell envelope Sec protein transport complex (11.9%) cytosol (11.8%)" "ATP binding (11.9%) metal ion binding (4.6%) protein-exporting ATPase activity (0.5%)" "IPR000185 (8.7%) IPR011116 (8.7%) IPR014018 (8.7%)" "Protein translocase subunit SecA (8.7%) SecA Wing/Scaffold (8.7%) SecA motor DEAD (8.7%)" KGLMTVEQAAQLAQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" LLTLTEGMTSEGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007121 (7.9%) IPR007641 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase, beta subunit, conserved site (7.9%) RNA polymerase Rpb2, domain 7 (7.9%)" DLEDLKNPAALAPTNLQLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071470 (33.3%) GO:0005886 (33.3%) GO:0008381 (33.3%) cellular response to osmotic stress (33.3%) plasma membrane (33.3%) mechanosensitive monoatomic ion channel activity (33.3%) "IPR006685 (25.8%) IPR030192 (25.8%) IPR010920 (24.2%)" "Mechanosensitive ion channel MscS (25.8%) Miniconductance mechanosensitive channel YbdG (25.8%) LSM domain superfamily (24.2%)" LEQMTWHDAMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004815 (20%) GO:0005524 (20%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) aspartate-tRNA ligase activity (20%) ATP binding (20%)" "IPR002312 (9.1%) IPR004115 (9.1%) IPR004364 (9.1%)" "Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%) Aminoacyl-tRNA synthetase, class II (D/K/N) (9.1%)" AGVSVGTVDR Bacteria Bacteria GO:0006355 (0.5%) "GO:0000976 (49.6%) GO:0003700 (49.6%) GO:0003677 (0.2%)" regulation of DNA-templated transcription (0.5%) "transcription cis-regulatory region binding (49.6%) DNA-binding transcription factor activity (49.6%) DNA binding (0.2%)" "IPR000843 (25.2%) IPR010982 (24.8%) IPR025997 (24.8%)" "LacI-type HTH domain (25.2%) Lambda repressor-like, DNA-binding domain superfamily (24.8%) Periplasmic binding protein (24.8%)" SAAFGLFGNNDLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) QDLWFATK root 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.2%) GO:0006102 (20.2%)" "GO:0004450 (20.2%) GO:0000287 (19.2%) GO:0051287 (19.2%)" "tricarboxylic acid cycle (20.2%) isocitrate metabolic process (20.2%)" "isocitrate dehydrogenase (NADP+) activity (20.2%) magnesium ion binding (19.2%) NAD binding (19.2%)" "IPR004790 (33.9%) IPR024084 (33.9%) IPR019818 (32.2%)" "Isocitrate dehydrogenase NADP-dependent (33.9%) Isopropylmalate dehydrogenase-like domain (33.9%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.2%)" LLTMPDFLK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (50.8%) IPR038377 (49.2%)" "Sodium/solute symporter (50.8%) Sodium/glucose symporter superfamily (49.2%)" FEMVAELEK Bacteria Bacteria 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0016491 (47.6%) GO:0016692 (2.4%)" "iron ion binding (50%) oxidoreductase activity (47.6%) NADH peroxidase activity (2.4%)" "IPR003251 (14%) IPR009040 (14%) IPR009078 (14%)" "Rubrerythrin, diiron-binding domain (14%) Ferritin-like diiron domain (14%) Ferritin-like superfamily (14%)" WSALTSMEDVQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.7%) 6.3.4.16 (49.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.7%) carbamoyl-phosphate synthase (ammonia) (49.3%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" YLEVTGLFTPR Pseudomonadati Bacteria Pseudomonadati "1.7.1.13 (99.3%) 1.7.1.- (0.4%) 3.5.4.16 (0.4%)" "preQ1 synthase (99.3%) With NAD(+) or NADP(+) as acceptor (0.4%) GTP cyclohydrolase I (0.4%)" "GO:0008616 (24.9%) GO:0006400 (23.9%)" "GO:0005737 (24.8%) GO:0005829 (0.1%)" "GO:0033739 (24.9%) GO:0016787 (1.1%) GO:0003934 (0.1%)" "tRNA queuosine(34) biosynthetic process (24.9%) tRNA modification (23.9%)" "cytoplasm (24.8%) cytosol (0.1%)" "preQ1 synthase activity (24.9%) hydrolase activity (1.1%) GTP cyclohydrolase I activity (0.1%)" "IPR016856 (25%) IPR029500 (25%) IPR043133 (25%)" "NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 (25%) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF (25%) GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase (25%)" FDFTDGDKLADWAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0000272 (36.7%) GO:0045493 (13.3%)" "GO:0004553 (33.3%) GO:0031176 (16.7%)" "polysaccharide catabolic process (36.7%) xylan catabolic process (13.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) endo-1,4-beta-xylanase activity (16.7%)" "IPR001000 (33.7%) IPR044846 (33.7%) IPR017853 (31.5%)" "Glycoside hydrolase family 10 domain (33.7%) Glycoside hydrolase family 10 (33.7%) Glycoside hydrolase superfamily (31.5%)" NFLYLGR root "2.6.1.16 (98.5%) 2.1.1.43 (0.2%) 2.4.-.- (0.1%)" "glutamine--fructose-6-phosphate transaminase (isomerizing) (98.5%) Transferred entry: 2.1.1.354 (0.2%) Glycosyltransferases (0.1%)" "GO:0006002 (12.7%) GO:0006047 (12.7%) GO:0006487 (12.7%)" "GO:0005829 (12.7%) GO:0016020 (0.2%) GO:0005737 (0.1%)" "GO:0004360 (12.7%) GO:0097367 (12.7%) GO:0016757 (0.1%)" "fructose 6-phosphate metabolic process (12.7%) UDP-N-acetylglucosamine metabolic process (12.7%) protein N-linked glycosylation (12.7%)" "cytosol (12.7%) membrane (0.2%) cytoplasm (0.1%)" "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.7%) carbohydrate derivative binding (12.7%) glycosyltransferase activity (0.1%)" "IPR001347 (12.2%) IPR046348 (12.2%) IPR035490 (12.1%)" "SIS domain (12.2%) SIS domain superfamily (12.2%) GlmS/FrlB, SIS domain 2 (12.1%)" LFALQDLLVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (33.3%) IPR039565 (33.3%) IPR011990 (31.5%)" "Outer membrane protein assembly factor BamD (33.3%) Outer membrane lipoprotein BamD-like (33.3%) Tetratricopeptide-like helical domain superfamily (31.5%)" EMASAGLLPGVK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006412 (20%) "GO:0005737 (20%) GO:0015935 (20%)" "GO:0003735 (20%) GO:0019843 (19.8%)" translation (20%) "cytoplasm (20%) small ribosomal subunit (20%)" "structural constituent of ribosome (20%) rRNA binding (19.8%)" "IPR001209 (28.6%) IPR018271 (28.3%) IPR023036 (28.3%)" "Small ribosomal subunit protein uS14 (28.6%) Small ribosomal subunit protein uS14, conserved site (28.3%) Small ribosomal subunit protein uS14, bacteria/plastid (28.3%)" TAYFTAENPWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.3%) IPR002469 (25.3%) IPR050278 (25.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.3%) Dipeptidylpeptidase IV, N-terminal domain (25.3%) Serine protease S9B/DPPIV (25.3%)" NVTLDNVQLSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (30%) GO:0005576 (30%) "GO:0004650 (30%) GO:0004557 (10%)" carbohydrate metabolic process (30%) extracellular region (30%) "polygalacturonase activity (30%) alpha-galactosidase activity (10%)" "IPR000743 (27.5%) IPR011050 (26.7%) IPR012334 (26.7%)" "Glycoside hydrolase, family 28 (27.5%) Pectin lyase fold/virulence factor (26.7%) Pectin lyase fold (26.7%)" LMEETGVSYASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ANLDGGGFTGQSQALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20.1%) IPR020574 (20.1%) IPR023035 (20.1%)" "Small ribosomal subunit protein uS9 (20.1%) Small ribosomal subunit protein uS9, conserved site (20.1%) Small ribosomal subunit protein uS9, bacteria/plastid (20.1%)" AGSALNFAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.6%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.6%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" DRVDDALCATR root 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.4%) "GO:0005737 (15.8%) GO:0005739 (0.1%)" "GO:0005524 (17.4%) GO:0140662 (17.4%) GO:0016853 (16.2%)" protein refolding (17.4%) "cytoplasm (15.8%) mitochondrion (0.1%)" "ATP binding (17.4%) ATP-dependent protein folding chaperone (17.4%) isomerase activity (16.2%)" "IPR001844 (17%) IPR002423 (17%) IPR027413 (16.7%)" "Chaperonin Cpn60/GroEL (17%) Chaperonin Cpn60/GroEL/TCP-1 family (17%) GroEL-like equatorial domain superfamily (16.7%)" NVGLTQNHNLSFSSGTDTSSLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FTTTFSPNYSHK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" LAELSALK root "2.3.2.27 (24.5%) 2.3.1.41 (12.2%) 1.8.1.2 (6.1%)" "RING-type E3 ubiquitin transferase (24.5%) beta-ketoacyl-[acyl-carrier-protein] synthase I (12.2%) assimilatory sulfite reductase (NADPH) (6.1%)" "GO:0007155 (9.8%) GO:0043107 (2.1%) GO:0033539 (1.8%)" "GO:0016020 (10.1%) GO:0009289 (7.7%) GO:0005737 (3.1%)" "GO:0005524 (2.6%) GO:0003995 (1.8%) GO:0050660 (1.8%)" "cell adhesion (9.8%) type IV pilus-dependent motility (2.1%) fatty acid beta-oxidation using acyl-CoA dehydrogenase (1.8%)" "membrane (10.1%) pilus (7.7%) cytoplasm (3.1%)" "ATP binding (2.6%) acyl-CoA dehydrogenase activity (1.8%) flavin adenine dinucleotide binding (1.8%)" "IPR001082 (7.5%) IPR045584 (7.5%) IPR012902 (7.4%)" "Fimbrial protein pilin (7.5%) Pilin-like (7.5%) Prokaryotic N-terminal methylation site (7.4%)" LCPLDLMPVFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.3%) "GO:0004553 (34.3%) GO:0030246 (31.5%)" carbohydrate metabolic process (34.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.3%) carbohydrate binding (31.5%)" "IPR000322 (12.9%) IPR048395 (12.9%) IPR051816 (12.9%)" "Glycoside hydrolase family 31, TIM barrel domain (12.9%) Glycosyl hydrolase family 31, C-terminal domain (12.9%) Glycosyl Hydrolase Family 31 (12.9%)" LAESQDNAHAFATAMGGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" KLLFVATK root "GO:0006412 (32.1%) GO:0006281 (1.5%) GO:0003341 (0%)" "GO:0022627 (32%) GO:0015935 (0.1%) GO:0005739 (0%)" "GO:0003735 (32.1%) GO:0003677 (1.5%) GO:0000166 (0.3%)" "translation (32.1%) DNA repair (1.5%) cilium movement (0%)" "cytosolic small ribosomal subunit (32%) small ribosomal subunit (0.1%) mitochondrion (0%)" "structural constituent of ribosome (32.1%) DNA binding (1.5%) nucleotide binding (0.3%)" "IPR001865 (24.5%) IPR005706 (24.5%) IPR023591 (24.5%)" "Small ribosomal subunit protein uS2 (24.5%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (24.5%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (24.5%)" YLDQVSDAHLSDDTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044341 (33.3%) GO:0005886 (33.3%) GO:0005436 (33.3%) sodium-dependent phosphate transport (33.3%) plasma membrane (33.3%) sodium:phosphate symporter activity (33.3%) "IPR003841 (26%) IPR004633 (26%) IPR038078 (24.4%)" "Sodium-dependent phosphate transport protein (26%) Na/Pi-cotransporter II-related/YqeW-like protein (26%) PhoU-like domain superfamily (24.4%)" VGGMEDYMTLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae VFVHEGQTVSAGQALFSLDSETYQAAVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" YLGSDELWEESENALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.6%) GO:0005737 (16.6%) "GO:0000049 (16.6%) GO:0004829 (16.6%) GO:0005524 (16.6%)" threonyl-tRNA aminoacylation (16.6%) cytoplasm (16.6%) "tRNA binding (16.6%) threonine-tRNA ligase activity (16.6%) ATP binding (16.6%)" "IPR002314 (7.8%) IPR002320 (7.8%) IPR004095 (7.8%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.8%) Threonine-tRNA ligase, class IIa (7.8%) TGS (7.8%)" QEAPLHLSNLSLLDPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR003256 (15%) IPR005824 (15%) IPR008991 (15%)" "Large ribosomal subunit protein uL24 (15%) KOW (15%) Translation protein SH3-like domain superfamily (15%)" NPMTPGLDYAAYPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006826 (25.7%) GO:0009279 (74.3%) iron ion transport (25.7%) cell outer membrane (74.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" HTEFLAAEPESCPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25.2%) "GO:0004834 (25.2%) GO:0052684 (25.2%) GO:0030170 (24.3%)" cytoplasm (25.2%) "tryptophan synthase activity (25.2%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25.2%) pyridoxal phosphate binding (24.3%)" "IPR001926 (22%) IPR023026 (22%) IPR006316 (21.2%)" "Tryptophan synthase beta chain-like, PALP domain (22%) Tryptophan synthase beta chain/beta chain-like (22%) Tryptophan synthase, beta chain-like (21.2%)" VAAEFDLTPYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.7%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.7%)" "IPR006104 (7.5%) IPR050347 (7.5%) IPR004199 (7.3%)" "Glycosyl hydrolases family 2, sugar binding domain (7.5%) Bacterial Beta-galactosidase (7.5%) Beta galactosidase small chain/ domain 5 (7.3%)" YLEDGGSADQEVYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VPAAGYELK Bacteria Bacteria 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (11.8%) GO:0030259 (11.8%) GO:0008360 (11.7%)" GO:0005886 (11.7%) "GO:0050511 (11.7%) GO:0051991 (6.1%) GO:0016758 (0.1%)" "carbohydrate metabolic process (11.8%) obsolete lipid glycosylation (11.8%) regulation of cell shape (11.7%)" plasma membrane (11.7%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.7%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (6.1%) hexosyltransferase activity (0.1%)" "IPR004276 (33.5%) IPR006009 (33.2%) IPR007235 (33.2%)" "Glycosyltransferase family 28, N-terminal domain (33.5%) N-acetylglucosaminyltransferase, MurG (33.2%) Glycosyl transferase, family 28, C-terminal (33.2%)" YGNEEQLKYEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.1%) IPR012910 (12.1%) IPR023996 (12.1%)" "Carboxypeptidase-like, regulatory domain superfamily (12.1%) TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein, SusC/RagA (12.1%)" LAGELLPCVFNVSAR Bacteria Bacteria "1.2.7.1 (93.8%) 1.2.1.51 (6.3%)" "pyruvate synthase (93.8%) pyruvate dehydrogenase (NADP(+)) (6.3%)" "GO:0006979 (14.7%) GO:0022900 (14.7%) GO:0044281 (11.7%)" "GO:0005506 (14.7%) GO:0030976 (14.7%) GO:0051539 (14.7%)" "response to oxidative stress (14.7%) electron transport chain (14.7%) small molecule metabolic process (11.7%)" "iron ion binding (14.7%) thiamine pyrophosphate binding (14.7%) 4 iron, 4 sulfur cluster binding (14.7%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" FTLFSMK root "2.7.11.1 (50%) 3.6.1.66 (50%)" "non-specific serine/threonine protein kinase (50%) XTP/dITP diphosphatase (50%)" "GO:0006357 (4.5%) GO:0043122 (2.5%) GO:0016567 (1.9%)" "GO:0005886 (5.1%) GO:0016020 (5.1%) GO:0009898 (2.5%)" "GO:0004866 (25.5%) GO:0016538 (4.5%) GO:0005164 (2.5%)" "regulation of transcription by RNA polymerase II (4.5%) regulation of canonical NF-kappaB signal transduction (2.5%) protein ubiquitination (1.9%)" "plasma membrane (5.1%) membrane (5.1%) cytoplasmic side of plasma membrane (2.5%)" "endopeptidase inhibitor activity (25.5%) cyclin-dependent protein serine/threonine kinase regulator activity (4.5%) tumor necrosis factor receptor binding (2.5%)" "IPR002890 (12.7%) IPR051802 (12.7%) IPR001599 (12.4%)" "Macroglobulin domain (12.7%) Alpha-2-macroglobulin-like (12.7%) Alpha-2-macroglobulin (12.4%)" MLTPTFLNTYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR038726 (34.3%) IPR027417 (33.3%) IPR011604 (32.4%)" "PD-(D/E)XK endonuclease-like domain, AddAB-type (34.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) PD-(D/E)XK endonuclease-like domain superfamily (32.4%)" NYFDTSHVEEVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (28.9%) GO:0006065 (11.3%)" "GO:0051287 (29.9%) GO:0003979 (28.9%) GO:0016616 (1%)" "polysaccharide biosynthetic process (28.9%) UDP-glucuronate biosynthetic process (11.3%)" "NAD binding (29.9%) UDP-glucose 6-dehydrogenase activity (28.9%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (1%)" "IPR001732 (11.3%) IPR014026 (11.3%) IPR014027 (11.3%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.3%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.3%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (11.3%)" VTSTVPEDAQEGDLTLSLDNGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" VNNSWMDAATDLAESSLGTSGTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" LLAQTALQLLAEGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" DLLLDPGFGFGK root 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (19.9%) GO:0042558 (0%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (19.9%) GO:0016740 (0.1%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (19.9%) pteridine-containing compound metabolic process (0%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (19.9%) transferase activity (0.1%)" "IPR000489 (25.1%) IPR045031 (25.1%) IPR011005 (25%)" "Pterin-binding domain (25.1%) Dihydropteroate synthase-like (25.1%) Dihydropteroate synthase-like superfamily (25%)" REFDDEALHELAESLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0007059 (25%) GO:0045881 (25%)" GO:0005694 (25%) GO:0003677 (25%) "chromosome segregation (25%) positive regulation of sporulation resulting in formation of a cellular spore (25%)" chromosome (25%) DNA binding (25%) "IPR003115 (16.7%) IPR004437 (16.7%) IPR036086 (16.7%)" "ParB-like, N-terminal domain (16.7%) ParB/RepB/Spo0J partition protein (16.7%) ParB/Sulfiredoxin superfamily (16.7%)" SNDPLYVVDGLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006826 (6.9%) GO:0044718 (3.4%)" GO:0009279 (86.2%) GO:0015344 (3.4%) "iron ion transport (6.9%) siderophore transmembrane transport (3.4%)" cell outer membrane (86.2%) siderophore uptake transmembrane transporter activity (3.4%) "IPR012910 (13.1%) IPR023997 (13.1%) IPR039426 (13.1%)" "TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.1%) TonB-dependent receptor-like (13.1%)" LPAVQTLVK root "6.3.4.16 (50%) 6.3.5.5 (50%)" "carbamoyl-phosphate synthase (ammonia) (50%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50%)" "GO:0006526 (0.3%) GO:0006541 (0.3%) GO:0044205 (0.3%)" GO:0005737 (0.5%) "GO:0005524 (33.2%) GO:0140662 (32.9%) GO:0051082 (31.9%)" "L-arginine biosynthetic process (0.3%) glutamine metabolic process (0.3%) 'de novo' UMP biosynthetic process (0.3%)" cytoplasm (0.5%) "ATP binding (33.2%) ATP-dependent protein folding chaperone (32.9%) unfolded protein binding (31.9%)" "IPR013126 (16.8%) IPR018181 (16.6%) IPR043129 (16.6%)" "Heat shock protein 70 family (16.8%) Heat shock protein 70, conserved site (16.6%) ATPase, nucleotide binding domain (16.6%)" FTVEALEAAPDFELAGLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25%) IPR010190 (25%) IPR032094 (25%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25%) Diaminopimelate dehydrogenase, Ddh (25%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25%)" LSTNVTDALVGSVPGLQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.3%) IPR023996 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" AADEGNCVFVGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) NSLATLAPHYTMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (85.7%) 2.4.1.8 (14.3%)" "glycogen phosphorylase (85.7%) maltose phosphorylase (14.3%)" GO:0005975 (33%) "GO:0008184 (33%) GO:0030170 (33%) GO:0050082 (0.9%)" carbohydrate metabolic process (33%) "glycogen phosphorylase activity (33%) pyridoxal phosphate binding (33%) maltose phosphorylase activity (0.9%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" VQVLEGGGELLDSEKPHFTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.7%) "GO:0005886 (16%) GO:0016020 (1.4%)" "GO:0016655 (16.7%) GO:0051537 (16.7%) GO:0009055 (16%)" sodium ion transport (16.7%) "plasma membrane (16%) membrane (1.4%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.7%) 2 iron, 2 sulfur cluster binding (16.7%) electron transfer activity (16%)" "IPR012675 (10.4%) IPR001041 (10%) IPR001433 (10%)" "Beta-grasp domain superfamily (10.4%) 2Fe-2S ferredoxin-type iron-sulfur binding domain (10%) Oxidoreductase FAD/NAD(P)-binding (10%)" AEVLKYDDYLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005737 (20.5%) GO:0016020 (0.3%)" "GO:0005524 (20.5%) GO:0016887 (20.5%) GO:0005525 (19.7%)" "cytoplasm (20.5%) membrane (0.3%)" "ATP binding (20.5%) ATP hydrolysis activity (20.5%) GTP binding (19.7%)" "IPR004095 (10.3%) IPR013029 (10.3%) IPR012675 (10.1%)" "TGS (10.3%) YchF, C-terminal domain (10.3%) Beta-grasp domain superfamily (10.1%)" VMLHQPLGGVQGQASDLELEAR Pseudomonadati Bacteria Pseudomonadati 3.4.21.92 (100%) endopeptidase Clp (100%) GO:0006515 (16.7%) "GO:0005737 (16.7%) GO:0009368 (16.7%)" "GO:0004176 (16.7%) GO:0004252 (16.7%) GO:0051117 (16.7%)" protein quality control for misfolded or incompletely synthesized proteins (16.7%) "cytoplasm (16.7%) endopeptidase Clp complex (16.7%)" "ATP-dependent peptidase activity (16.7%) serine-type endopeptidase activity (16.7%) ATPase binding (16.7%)" "IPR001907 (28%) IPR023562 (28%) IPR029045 (28%)" "ATP-dependent Clp protease proteolytic subunit (28%) Clp protease proteolytic subunit /Translocation-enhancing protein TepA (28%) ClpP/crotonase-like domain superfamily (28%)" LLDFSEVEQTLNSNDRR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (33%) "GO:0051536 (34.1%) GO:0016639 (33%)" glutamate biosynthetic process (33%) "iron-sulfur cluster binding (34.1%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (33%)" "IPR009051 (16.9%) IPR028261 (16.9%) IPR051394 (16.9%)" "Alpha-helical ferredoxin (16.9%) Dihydroprymidine dehydrogenase domain II (16.9%) Glutamate Synthase (16.9%)" ASSLYTVHTPVPAGHDYFDEALFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (92.9%) 2.4.1.8 (7.1%)" "glycogen phosphorylase (92.9%) maltose phosphorylase (7.1%)" GO:0005975 (33.2%) "GO:0008184 (33.2%) GO:0030170 (33.2%) GO:0050082 (0.5%)" carbohydrate metabolic process (33.2%) "glycogen phosphorylase activity (33.2%) pyridoxal phosphate binding (33.2%) maltose phosphorylase activity (0.5%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" YNLLASLR root "3.5.1.1 (50%) 3.6.3.- (16.7%) 4.4.1.1 (16.7%)" "asparaginase (50%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (16.7%) cystathionine gamma-lyase (16.7%)" "GO:0006508 (12.3%) GO:0006528 (4.1%) GO:0006826 (1.4%)" "GO:0009279 (20.5%) GO:0016020 (4.1%) GO:0005737 (1.4%)" "GO:0004252 (12.3%) GO:0003964 (8.2%) GO:0004067 (4.1%)" "proteolysis (12.3%) asparagine metabolic process (4.1%) iron ion transport (1.4%)" "cell outer membrane (20.5%) membrane (4.1%) cytoplasm (1.4%)" "serine-type endopeptidase activity (12.3%) RNA-directed DNA polymerase activity (8.2%) asparaginase activity (4.1%)" "IPR000531 (7.1%) IPR008969 (7.1%) IPR012910 (7.1%)" "TonB-dependent receptor-like, beta-barrel (7.1%) Carboxypeptidase-like, regulatory domain superfamily (7.1%) TonB-dependent receptor, plug domain (7.1%)" FPGGCLVEGTDLDTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (16%) IPR010720 (16%) IPR051563 (16%)" "Carbohydrate-binding, CenC-like (16%) Alpha-L-arabinofuranosidase, C-terminal (16%) Glycosyl Hydrolase Family 51 (16%)" QVNLESLNVSASSLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (20%) GO:0009099 (20%)" GO:0005829 (20%) "GO:0003984 (20%) GO:1990610 (20%)" "isoleucine biosynthetic process (20%) L-valine biosynthetic process (20%)" cytosol (20%) "acetolactate synthase activity (20%) acetolactate synthase regulator activity (20%)" "IPR002912 (14.3%) IPR004789 (14.3%) IPR019455 (14.3%)" "ACT domain (14.3%) Acetolactate synthase, small subunit (14.3%) Acetolactate synthase, small subunit, C-terminal (14.3%)" SETDAAWLQGGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011042 (21%) IPR011659 (21%) IPR001375 (20.3%)" "Six-bladed beta-propeller, TolB-like (21%) WD40-like beta-propeller (21%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20.3%)" EAGDYVQAGEVLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" GPTLTPGYYHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (34.3%) IPR042099 (33.1%) IPR020845 (32.5%)" "AMP-dependent synthetase/ligase domain (34.3%) ANL, N-terminal domain (33.1%) AMP-binding, conserved site (32.5%)" SLNVLHDSFFLSEYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.3 (54.1%) 2.7.2.4 (45.9%)" "homoserine dehydrogenase (54.1%) aspartate kinase (45.9%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.1%) IPR001341 (7.1%) IPR001342 (7.1%)" "Aspartate/glutamate/uridylate kinase (7.1%) Aspartate kinase (7.1%) Homoserine dehydrogenase, catalytic (7.1%)" FVNHLMYDGKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (20.1%) GO:0000028 (0.1%)" "GO:0015935 (20.1%) GO:0005840 (0.2%) GO:0022627 (0.1%)" "GO:0003735 (20.1%) GO:0019843 (20.1%) GO:0000049 (19.1%)" "translation (20.1%) ribosomal small subunit assembly (0.1%)" "small ribosomal subunit (20.1%) ribosome (0.2%) cytosolic small ribosomal subunit (0.1%)" "structural constituent of ribosome (20.1%) rRNA binding (20.1%) tRNA binding (19.1%)" "IPR023798 (24.9%) IPR036823 (24.9%) IPR000235 (24.8%)" "Small ribosomal subunit protein uS7 domain (24.9%) Small ribosomal subunit protein uS7 domain superfamily (24.9%) Small ribosomal subunit protein uS7 (24.8%)" ELLAEADACKDELSVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0035435 (33.3%) GO:0016020 (33.3%) GO:0005315 (33.3%) phosphate ion transmembrane transport (33.3%) membrane (33.3%) phosphate transmembrane transporter activity (33.3%) IPR001204 (100%) Phosphate transporter (100%) YEYVAFR root "GO:0006974 (36.7%) GO:0006508 (5%) GO:0006352 (1.7%)" "GO:0016020 (33.3%) GO:0042651 (1.7%) GO:0098826 (1.7%)" "GO:0008234 (5%) GO:0003677 (1.7%) GO:0008270 (1.7%)" "DNA damage response (36.7%) proteolysis (5%) DNA-templated transcription initiation (1.7%)" "membrane (33.3%) thylakoid membrane (1.7%) endoplasmic reticulum tubular network membrane (1.7%)" "cysteine-type peptidase activity (5%) DNA binding (1.7%) zinc ion binding (1.7%)" "IPR007497 (23.7%) IPR052022 (23.7%) IPR016907 (22.6%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (23.7%) 26 kDa periplasmic antigen-related (23.7%) Uncharacterised conserved protein UCP029033, periplasmic protein (22.6%)" HTETGAAMPADLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR034005 (20.5%) IPR045090 (20.5%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidyl-dipeptidase DCP (20.5%) Peptidase M3A/M3B (20.5%)" NYYWSSAMTTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" LALMDWLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0045892 (19.7%) GO:1900376 (19.7%)" "GO:0003700 (21.3%) GO:0000976 (19.7%) GO:0008270 (19.7%)" "negative regulation of DNA-templated transcription (19.7%) regulation of secondary metabolite biosynthetic process (19.7%)" "DNA-binding transcription factor activity (21.3%) transcription cis-regulatory region binding (19.7%) zinc ion binding (19.7%)" "IPR002481 (25.5%) IPR036388 (25.5%) IPR036390 (25.5%)" "Ferric-uptake regulator (25.5%) Winged helix-like DNA-binding domain superfamily (25.5%) Winged helix DNA-binding domain superfamily (25.5%)" LAATLLYNGCEWGQATSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.3%) IPR033985 (35.3%) IPR011990 (29.4%)" "RagB/SusD domain (35.3%) SusD-like, N-terminal (35.3%) Tetratricopeptide-like helical domain superfamily (29.4%)" YKPTFTPHVDCGDNVLLLNAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (20%) GO:0017148 (20%)" GO:0022625 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" cytosolic large ribosomal subunit (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (29.3%) IPR005823 (29.3%) IPR036899 (29.3%)" "Large ribosomal subunit protein uL13 (29.3%) Large ribosomal subunit protein uL13, bacteria (29.3%) Large ribosomal subunit protein uL13 superfamily (29.3%)" LFVLPVEDTVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (25.6%) IPR011322 (25.6%) IPR015867 (25.6%)" "Nitrogen regulatory protein PII (25.6%) Nitrogen regulatory PII-like, alpha/beta (25.6%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25.6%)" SADANSCFSDLFYTKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.8%) IPR011990 (32.6%) IPR012944 (32.6%)" "SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (32.6%) RagB/SusD domain (32.6%)" EKADETLLEFMQTDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DGLNEWLDAHGCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.-.- (100%) Acting on the CH-CH group of donors (100%) "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) GO:0004152 (25%) "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) dihydroorotate dehydrogenase activity (25%) "IPR001295 (12.5%) IPR005720 (12.5%) IPR012135 (12.5%)" "Dihydroorotate dehydrogenase, conserved site (12.5%) Dihydroorotate dehydrogenase, catalytic (12.5%) Dihydroorotate dehydrogenase, class 1/ 2 (12.5%)" QEFGTGYDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" DNEQLMDLLNNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0043200 (31.8%) GO:0005829 (31.8%) GO:0043565 (36.4%) response to amino acid (31.8%) cytosol (31.8%) sequence-specific DNA binding (36.4%) "IPR000485 (16.3%) IPR011008 (16.3%) IPR019887 (16.3%)" "AsnC-type HTH domain (16.3%) Dimeric alpha-beta barrel (16.3%) Transcription regulator AsnC/Lrp, ligand binding domain (16.3%)" YDFQFVNKR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.17.4.1 (100%) ribonucleoside-diphosphate reductase (100%) "GO:0071897 (21.1%) GO:0009263 (15.8%)" "GO:0004748 (21.1%) GO:0031419 (21.1%) GO:0005524 (15.8%)" "DNA biosynthetic process (21.1%) deoxyribonucleotide biosynthetic process (15.8%)" "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (21.1%) cobalamin binding (21.1%) ATP binding (15.8%)" "IPR000788 (26.7%) IPR013344 (26.7%) IPR050862 (26.7%)" "Ribonucleotide reductase large subunit, C-terminal (26.7%) Ribonucleotide reductase, adenosylcobalamin-dependent (26.7%) Ribonucleoside diphosphate reductase class-2 (26.7%)" AMELHTALVEAAAENDEGLMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" YWVNAGEVNNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006826 (26.7%) GO:0009279 (73.3%) iron ion transport (26.7%) cell outer membrane (73.3%) "IPR000531 (13.8%) IPR039426 (13.8%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor-like (13.8%) TonB-dependent receptor, plug domain (12.5%)" LLDGTVFDATSK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (49.2%) GO:0003755 (50.8%) protein folding (49.2%) peptidyl-prolyl cis-trans isomerase activity (50.8%) "IPR001179 (31.7%) IPR000774 (30.7%) IPR046357 (30.7%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (31.7%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (30.7%) Peptidyl-prolyl cis-trans isomerase domain superfamily (30.7%)" SGFAPLLGTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (28.6%) GO:0008654 (28.6%)" GO:0016020 (14.1%) GO:0004512 (28.6%) "inositol biosynthetic process (28.6%) phospholipid biosynthetic process (28.6%)" membrane (14.1%) inositol-3-phosphate synthase activity (28.6%) "IPR002587 (33.5%) IPR013021 (33.5%) IPR036291 (33.1%)" "Myo-inositol-1-phosphate synthase (33.5%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.5%) NAD(P)-binding domain superfamily (33.1%)" EHLLNCMMETLSEPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" LELCHTLNGSALALPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.11 (100%) serine--tRNA ligase (100%) "GO:0006434 (24.9%) GO:0006412 (0.2%)" GO:0005737 (24.9%) "GO:0004828 (24.9%) GO:0005524 (24.9%) GO:0016874 (0.2%)" "seryl-tRNA aminoacylation (24.9%) translation (0.2%)" cytoplasm (24.9%) "serine-tRNA ligase activity (24.9%) ATP binding (24.9%) ligase activity (0.2%)" "IPR045864 (14.5%) IPR002314 (14.3%) IPR002317 (14.3%)" "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.5%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (14.3%) Serine-tRNA ligase, type1 (14.3%)" YYLYGTHLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20%) IPR023296 (20%) IPR032291 (20%)" "Glycoside hydrolase, family 43 (20%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (20%) Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (20%)" WGLFGDTYGGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" LAELYLTR root "2.3.2.27 (81.3%) 1.2.1.41 (6.3%) 2.7.13.3 (6.3%)" "RING-type E3 ubiquitin transferase (81.3%) glutamate-5-semialdehyde dehydrogenase (6.3%) histidine kinase (6.3%)" "GO:0030334 (8.7%) GO:0007162 (8.2%) GO:0008360 (8.2%)" "GO:0005886 (10.4%) GO:0002116 (8.7%) GO:0009279 (8.7%)" "GO:0017154 (8.7%) GO:0008270 (2.3%) GO:0061630 (2.1%)" "regulation of cell migration (8.7%) negative regulation of cell adhesion (8.2%) regulation of cell shape (8.2%)" "plasma membrane (10.4%) semaphorin receptor complex (8.7%) cell outer membrane (8.7%)" "semaphorin receptor activity (8.7%) zinc ion binding (2.3%) ubiquitin protein ligase activity (2.1%)" "IPR011990 (5.9%) IPR012944 (5.6%) IPR013548 (5.6%)" "Tetratricopeptide-like helical domain superfamily (5.9%) RagB/SusD domain (5.6%) Plexin, cytoplasmic RasGAP domain (5.6%)" AELEGSVFHLSADAWK Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.6%) GO:0006096 (12.6%) GO:0019563 (12.6%)" "GO:0005829 (12.6%) GO:0016020 (12.2%)" GO:0004807 (12.6%) "gluconeogenesis (12.6%) glycolytic process (12.6%) glycerol catabolic process (12.6%)" "cytosol (12.6%) membrane (12.2%)" triose-phosphate isomerase activity (12.6%) "IPR000652 (17%) IPR020861 (17%) IPR009908 (16.5%)" "Triosephosphate isomerase (17%) Triosephosphate isomerase, active site (17%) Methylamine utilisation protein, MauE (16.5%)" YGFVVRPEANK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.3%) "GO:0005840 (20.3%) GO:1990904 (20.3%)" "GO:0003735 (20.3%) GO:0019843 (18.6%)" translation (20.3%) "ribosome (20.3%) ribonucleoprotein complex (20.3%)" "structural constituent of ribosome (20.3%) rRNA binding (18.6%)" "IPR012677 (33.3%) IPR012678 (33.3%) IPR013025 (33.3%)" "Nucleotide-binding alpha-beta plait domain superfamily (33.3%) Ribosomal protein uL23/eL15/eS24 core domain superfamily (33.3%) Large ribosomal subunit protein uL23-like (33.3%)" NLAVLAHVDHGK root 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0009409 (8.5%) GO:0000027 (8.5%) GO:0010467 (8.3%)" "GO:0005829 (10.3%) GO:1990904 (10.3%) GO:0005737 (1.3%)" "GO:0003924 (11.8%) GO:0005525 (11.8%) GO:0043022 (8.8%)" "response to cold (8.5%) ribosomal large subunit assembly (8.5%) gene expression (8.3%)" "cytosol (10.3%) ribonucleoprotein complex (10.3%) cytoplasm (1.3%)" "GTPase activity (11.8%) GTP binding (11.8%) ribosome binding (8.8%)" "IPR000795 (7.1%) IPR005225 (7.1%) IPR027417 (7.1%)" "Translational (tr)-type GTP-binding domain (7.1%) Small GTP-binding domain (7.1%) P-loop containing nucleoside triphosphate hydrolase (7.1%)" LNPGDTVHTLENLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000271 (25%) "GO:0016616 (25%) GO:0016628 (25%) GO:0051287 (25%)" polysaccharide biosynthetic process (25%) "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (25%) oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor (25%) NAD binding (25%)" "IPR001732 (12.6%) IPR014026 (12.6%) IPR014027 (12.6%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (12.6%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (12.6%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (12.6%)" FHAGFNYQFDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009636 (23.7%) GO:0005886 (25.8%) "GO:0042910 (25.8%) GO:0015562 (24.7%)" response to toxic substance (23.7%) plasma membrane (25.8%) "xenobiotic transmembrane transporter activity (25.8%) efflux transmembrane transporter activity (24.7%)" "IPR001036 (34.2%) IPR004764 (32.9%) IPR027463 (32.9%)" "Acriflavin resistance protein (34.2%) Multidrug resistance protein MdtF-like (32.9%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (32.9%)" WGLFPSAALAWR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (23.7%) GO:0009279 (76.3%) iron ion transport (23.7%) cell outer membrane (76.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" MMQEALENAEQTATQFAENSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006974 (50%) GO:0016020 (50%) DNA damage response (50%) membrane (50%) "IPR007497 (33.3%) IPR016907 (33.3%) IPR052022 (33.3%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.3%) Uncharacterised conserved protein UCP029033, periplasmic protein (33.3%) 26 kDa periplasmic antigen-related (33.3%)" EETQCFAFLAGHESFAAAEGALK Bacteria Bacteria IPR025964 (100%) GGGtGRT protein (100%) VGDTFLNMEAFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005975 (50%) "GO:0004553 (28.6%) GO:0004565 (21.4%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (28.6%) beta-galactosidase activity (21.4%)" "IPR001944 (14.2%) IPR008979 (14.2%) IPR017853 (14.2%)" "Glycoside hydrolase, family 35 (14.2%) Galactose-binding-like domain superfamily (14.2%) Glycoside hydrolase superfamily (14.2%)" FRDLWPASADDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" FQLALPQQGDNLTALHAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) TNTLLQSAFFR Bacteria Bacteria "1.2.7.1 (78.7%) 1.2.7.- (16.9%) 1.2.1.51 (4.5%)" "pyruvate synthase (78.7%) With an iron-sulfur protein as acceptor (16.9%) pyruvate dehydrogenase (NADP(+)) (4.5%)" "GO:0006979 (14.7%) GO:0022900 (14.6%) GO:0044281 (12%)" "GO:0051539 (14.7%) GO:0005506 (14.6%) GO:0030976 (14.5%)" "response to oxidative stress (14.7%) electron transport chain (14.6%) small molecule metabolic process (12%)" "4 iron, 4 sulfur cluster binding (14.7%) iron ion binding (14.6%) thiamine pyrophosphate binding (14.5%)" "IPR050722 (7.8%) IPR002869 (7.7%) IPR011895 (7.7%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.8%) Pyruvate-flavodoxin oxidoreductase, central domain (7.7%) Pyruvate-flavodoxin oxidoreductase (7.7%)" SLTEALYPLTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" GTVSWDNVFVETSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.6%) IPR023997 (15.6%) IPR039426 (15.6%)" "TonB-dependent receptor, plug domain (15.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.6%) TonB-dependent receptor-like (15.6%)" AENGMLYDPVTLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20.1%) GO:0006183 (20.1%)" "GO:0003938 (20.1%) GO:0046872 (20.1%) GO:0000166 (19.6%)" "GMP biosynthetic process (20.1%) GTP biosynthetic process (20.1%)" "IMP dehydrogenase activity (20.1%) metal ion binding (20.1%) nucleotide binding (19.6%)" "IPR000644 (16.8%) IPR001093 (16.8%) IPR005990 (16.8%)" "CBS domain (16.8%) IMP dehydrogenase/GMP reductase (16.8%) Inosine-5'-monophosphate dehydrogenase (16.8%)" VPVFDGFEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" QWGSVTPGHPELDLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.2.1.1 (96.3%) 1.2.4.4 (3.7%)" "transketolase (96.3%) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (3.7%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (24.1%) GO:0003863 (0.9%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (24.1%) branched-chain 2-oxo acid dehydrogenase activity (0.9%)" "IPR005474 (12.8%) IPR029061 (12.8%) IPR033247 (12.8%)" "Transketolase, N-terminal (12.8%) Thiamin diphosphate-binding fold (12.8%) Transketolase family (12.8%)" TVAVLGAGPAGLVAANQLNHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (33.3%) "GO:0016639 (33.3%) GO:0051536 (33.3%)" glutamate biosynthetic process (33.3%) "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (33.3%) iron-sulfur cluster binding (33.3%)" "IPR006005 (16.7%) IPR009051 (16.7%) IPR023753 (16.7%)" "Glutamate synthase, NADH/NADPH, small subunit 1 (16.7%) Alpha-helical ferredoxin (16.7%) FAD/NAD(P)-binding domain (16.7%)" DYSAPVLSLTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (31.6%) GO:0046677 (31.6%)" GO:0016020 (5.1%) GO:0008800 (31.6%) "beta-lactam antibiotic catabolic process (31.6%) response to antibiotic (31.6%)" membrane (5.1%) beta-lactamase activity (31.6%) "IPR000871 (25.5%) IPR023650 (25.5%) IPR045155 (25.5%)" "Beta-lactamase, class-A (25.5%) Beta-lactamase, class-A active site (25.5%) Beta-lactamase class A, catalytic domain (25.5%)" LSYLGFVSQTVVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" DQCDLALYPESYFQDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.9%) IPR033985 (33.9%) IPR011990 (32.1%)" "RagB/SusD domain (33.9%) SusD-like, N-terminal (33.9%) Tetratricopeptide-like helical domain superfamily (32.1%)" VVATLFFEPSTR root 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006520 (16.8%) GO:0006207 (16.5%) GO:0044205 (16.5%)" "GO:0005829 (16.5%) GO:0016020 (0.1%)" "GO:0016597 (16.8%) GO:0004070 (16.5%) GO:0016743 (0.3%)" "amino acid metabolic process (16.8%) 'de novo' pyrimidine nucleobase biosynthetic process (16.5%) 'de novo' UMP biosynthetic process (16.5%)" "cytosol (16.5%) membrane (0.1%)" "amino acid binding (16.8%) aspartate carbamoyltransferase activity (16.5%) carboxyl- or carbamoyltransferase activity (0.3%)" "IPR006130 (20.2%) IPR006132 (20.2%) IPR036901 (20.1%)" "Aspartate/ornithine carbamoyltransferase (20.2%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20.2%) Aspartate/ornithine carbamoyltransferase superfamily (20.1%)" YYRNEEAGSDYSTQQSASSNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" DFMAAVEPLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.199 (100%) 16S rRNA (cytosine(1402)-N(4))-methyltransferase (100%) GO:0070475 (33.3%) GO:0005737 (33.3%) GO:0071424 (33.3%) rRNA base methylation (33.3%) cytoplasm (33.3%) rRNA (cytosine-N4-)-methyltransferase activity (33.3%) "IPR002903 (34.9%) IPR023397 (32.6%) IPR029063 (32.6%)" "Ribosomal RNA small subunit methyltransferase H (34.9%) S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily (32.6%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (32.6%)" NSDYGYMADFGDLFLPDNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" MTAEQLENALTEK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.6.1.- (100%) Transaminases (100%) GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (31.7%) GO:0004069 (1.6%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (31.7%) L-aspartate:2-oxoglutarate aminotransferase activity (1.6%)" "IPR004838 (16.9%) IPR004839 (16.9%) IPR015421 (16.9%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.9%) Aminotransferase, class I/classII, large domain (16.9%) Pyridoxal phosphate-dependent transferase, major domain (16.9%)" HVPVLEPLEGGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.15.1.2 (100%) superoxide reductase (100%) GO:0019430 (32.4%) "GO:0005506 (33.8%) GO:0016491 (17.6%) GO:0050605 (16.2%)" removal of superoxide radicals (32.4%) "iron ion binding (33.8%) oxidoreductase activity (17.6%) superoxide reductase activity (16.2%)" "IPR002742 (17.3%) IPR051233 (17.3%) IPR004462 (16.5%)" "Desulfoferrodoxin, ferrous iron-binding domain (17.3%) Desulfoferrodoxin superoxide reductase (17.3%) Desulfoferrodoxin, N-terminal domain (16.5%)" GMGTVSGSDPLYLLDGVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" YAGPNTLLMEAAELTEK Pseudomonadati Bacteria Pseudomonadati 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (29%) GO:0008610 (6.5%)" GO:0016020 (29%) GO:0008780 (35.5%) "lipid A biosynthetic process (29%) lipid biosynthetic process (6.5%)" membrane (29%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (35.5%) "IPR010137 (20.6%) IPR011004 (20.6%) IPR029098 (20.6%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.6%) Trimeric LpxA-like superfamily (20.6%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.6%)" NVGNAPSDATELSYFGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" LVANPDDEEALKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.4 (100%) DNA 3'-5' helicase (100%) GO:0000725 (14.3%) "GO:0005829 (14.3%) GO:0033202 (14.3%)" "GO:0003677 (14.3%) GO:0005524 (14.3%) GO:0043138 (14.3%)" recombinational repair (14.3%) "cytosol (14.3%) DNA helicase complex (14.3%)" "DNA binding (14.3%) ATP binding (14.3%) 3'-5' DNA helicase activity (14.3%)" "IPR000212 (20.5%) IPR014016 (20.5%) IPR014017 (20.5%)" "DNA helicase, UvrD/REP type (20.5%) UvrD-like helicase, ATP-binding domain (20.5%) UvrD-like DNA helicase, C-terminal (20.5%)" NYLSSMPGEYGDLLSRPTDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.2%) IPR019533 (25.2%) IPR019758 (25.2%)" "Peptidase S26A, signal peptidase I (25.2%) Peptidase S26 (25.2%) Peptidase S26A, signal peptidase I, conserved site (25.2%)" MKLEDFNFAGHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" LNYSFDGK root 3.1.3.16 (100%) protein-serine/threonine phosphatase (100%) "GO:0000028 (2.9%) GO:0000447 (2.9%) GO:0000472 (2.9%)" "GO:0009279 (39.1%) GO:0005829 (10.1%) GO:0005737 (4.3%)" "GO:0004252 (10.1%) GO:0070012 (10.1%) GO:0004722 (1.4%)" "ribosomal small subunit assembly (2.9%) endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (2.9%) endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (2.9%)" "cell outer membrane (39.1%) cytosol (10.1%) cytoplasm (4.3%)" "serine-type endopeptidase activity (10.1%) oligopeptidase activity (10.1%) protein serine/threonine phosphatase activity (1.4%)" "IPR012910 (10.2%) IPR023996 (10.2%) IPR039426 (10.2%)" "TonB-dependent receptor, plug domain (10.2%) TonB-dependent outer membrane protein, SusC/RagA (10.2%) TonB-dependent receptor-like (10.2%)" VEVVTPEENMGDVLGDLNKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (20.2%) GO:0005737 (19.8%) "GO:0003746 (20.2%) GO:0005525 (20.2%) GO:0003924 (19.8%)" ribosome disassembly (20.2%) cytoplasm (19.8%) "translation elongation factor activity (20.2%) GTP binding (20.2%) GTPase activity (19.8%)" "IPR000640 (6.3%) IPR004161 (6.3%) IPR005517 (6.3%)" "Elongation factor EFG, domain V-like (6.3%) Translation elongation factor EFTu-like, domain 2 (6.3%) Translation elongation factor EFG/EF2, domain IV (6.3%)" GLNWQVENTLTYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" LLTTTNLTEPFFLSEQTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) EDVSAYLDFLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (23.2%) GO:0016020 (1.8%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (23.2%) membrane (1.8%)" protein-disulfide reductase activity (25%) "IPR003834 (25.2%) IPR013766 (25.2%) IPR028250 (25.2%)" "Cytochrome C biogenesis protein, transmembrane domain (25.2%) Thioredoxin domain (25.2%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.2%)" FELMVNGK root 6.1.1.6 (100%) lysine--tRNA ligase (100%) "GO:0006430 (16.1%) GO:0006351 (1%) GO:0006614 (0%)" "GO:0005829 (16.1%) GO:0005737 (0%) GO:0005786 (0%)" "GO:0000049 (16.1%) GO:0004824 (16.1%) GO:0005524 (16.1%)" "lysyl-tRNA aminoacylation (16.1%) DNA-templated transcription (1%) SRP-dependent cotranslational protein targeting to membrane (0%)" "cytosol (16.1%) cytoplasm (0%) signal recognition particle, endoplasmic reticulum targeting (0%)" "tRNA binding (16.1%) lysine-tRNA ligase activity (16.1%) ATP binding (16.1%)" "IPR004364 (11.7%) IPR006195 (11.7%) IPR045864 (11.7%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (11.7%) Aminoacyl-tRNA synthetase, class II (11.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (11.7%)" LTNSTQGVFEDR Bacteria Bacteria "2.5.1.49 (76.7%) 4.4.1.11 (20.9%) 2.5.1.48 (2.3%)" "O-acetylhomoserine aminocarboxypropyltransferase (76.7%) methionine gamma-lyase (20.9%) cystathionine gamma-synthase (2.3%)" "GO:0006535 (13.9%) GO:0019346 (13.9%) GO:0071269 (13.9%)" GO:0005737 (13.9%) "GO:0003961 (13.9%) GO:0004124 (13.9%) GO:0030170 (13.9%)" "cysteine biosynthetic process from serine (13.9%) transsulfuration (13.9%) L-homocysteine biosynthetic process (13.9%)" cytoplasm (13.9%) "O-acetylhomoserine aminocarboxypropyltransferase activity (13.9%) cysteine synthase activity (13.9%) pyridoxal phosphate binding (13.9%)" "IPR000277 (17%) IPR006235 (17%) IPR015421 (16.9%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17%) Pyridoxal phosphate-dependent transferase, major domain (16.9%)" TQEYYNTMLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25.1%) GO:0005737 (25.1%) "GO:0004134 (25.1%) GO:2001070 (24.6%)" carbohydrate metabolic process (25.1%) cytoplasm (25.1%) "4-alpha-glucanotransferase activity (25.1%) starch binding (24.6%)" "IPR003385 (20.9%) IPR002044 (20.4%) IPR017853 (19.9%)" "Glycoside hydrolase, family 77 (20.9%) Carbohydrate binding module family 20 (20.4%) Glycoside hydrolase superfamily (19.9%)" LSSNGETVLGATVTATHQPSGTVYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR012910 (17.1%) IPR039426 (17.1%) IPR057601 (17.1%)" "TonB-dependent receptor, plug domain (17.1%) TonB-dependent receptor-like (17.1%) TonB-dependent transporter Oar-like, beta-barrel domain (17.1%)" NQLLDLFAR Bacteroidota Bacteria Pseudomonadati Bacteroidota "6.1.1.20 (87.5%) 5.1.3.4 (12.5%)" "phenylalanine--tRNA ligase (87.5%) L-ribulose-5-phosphate 4-epimerase (12.5%)" "GO:0006432 (14.9%) GO:0019323 (2.1%)" "GO:0005737 (14.9%) GO:0005829 (2.1%)" "GO:0000049 (14.9%) GO:0000287 (14.9%) GO:0004826 (14.9%)" "phenylalanyl-tRNA aminoacylation (14.9%) pentose catabolic process (2.1%)" "cytoplasm (14.9%) cytosol (2.1%)" "tRNA binding (14.9%) magnesium ion binding (14.9%) phenylalanine-tRNA ligase activity (14.9%)" "IPR002319 (13.5%) IPR004188 (13.5%) IPR004529 (13.5%)" "Phenylalanyl-tRNA synthetase (13.5%) Phenylalanine-tRNA ligase, class II, N-terminal (13.5%) Phenylalanyl-tRNA synthetase, class IIc, alpha subunit (13.5%)" SMAGTDADHWFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (23.1%) GO:0009636 (17.9%) GO:0043418 (17.9%)" GO:0005737 (17.9%) GO:0070005 (23.1%) "proteolysis (23.1%) response to toxic substance (17.9%) homocysteine catabolic process (17.9%)" cytoplasm (17.9%) cysteine-type aminopeptidase activity (23.1%) "IPR004134 (32.1%) IPR000169 (30.4%) IPR038765 (30.4%)" "Peptidase C1B, bleomycin hydrolase (32.1%) Cysteine peptidase, cysteine active site (30.4%) Papain-like cysteine peptidase superfamily (30.4%)" GGFLWGPYAEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GCMLLKPYGYALWEK root 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (19.8%) "GO:0005737 (19.8%) GO:0017101 (19.8%)" "GO:0004827 (19.8%) GO:0005524 (19.8%) GO:0003995 (0.5%)" prolyl-tRNA aminoacylation (19.8%) "cytoplasm (19.8%) aminoacyl-tRNA synthetase multienzyme complex (19.8%)" "proline-tRNA ligase activity (19.8%) ATP binding (19.8%) acyl-CoA dehydrogenase activity (0.5%)" "IPR004499 (11.1%) IPR002314 (10.9%) IPR004154 (10.9%)" "Proline-tRNA ligase, class IIa, archaeal-type (11.1%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (10.9%) Anticodon-binding (10.9%)" SAEEVYDQLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003723 (33.3%) GO:0008990 (33.3%) GO:0070043 (33.3%)" "RNA binding (33.3%) rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%)" "IPR000241 (16.8%) IPR002052 (16.8%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (16.8%) DNA methylase, N-6 adenine-specific, conserved site (16.8%) THUMP domain (16.8%)" PYFSVASGGGTGR Bacteria Bacteria IPR025964 (100%) GGGtGRT protein (100%) DCPLLLFQDR Pseudomonadati Bacteria Pseudomonadati GO:0051596 (50%) GO:0016491 (50%) methylglyoxal catabolic process (50%) oxidoreductase activity (50%) "IPR005399 (33.7%) IPR023210 (33.7%) IPR036812 (32.6%)" "Potassium channel, voltage-dependent, beta subunit, KCNAB-related (33.7%) NADP-dependent oxidoreductase domain (33.7%) NAD(P)-dependent oxidoreductase domain superfamily (32.6%)" VLLTTLTK root "3.1.25.- (98.6%) 2.1.1.228 (0.7%) 4.1.1.81 (0.4%)" "Site-specific endodeoxyribonucleases specific for altered bases (98.6%) tRNA (guanine(37)-N(1))-methyltransferase (0.7%) threonine-phosphate decarboxylase (0.4%)" "GO:0006289 (12.5%) GO:0009432 (12.1%) GO:0000715 (0%)" "GO:0009380 (12.6%) GO:0005737 (12.2%) GO:0005886 (0%)" "GO:0005524 (12.6%) GO:0003677 (12.6%) GO:0016887 (12.6%)" "nucleotide-excision repair (12.5%) SOS response (12.1%) nucleotide-excision repair, DNA damage recognition (0%)" "excinuclease repair complex (12.6%) cytoplasm (12.2%) plasma membrane (0%)" "ATP binding (12.6%) DNA binding (12.6%) ATP hydrolysis activity (12.6%)" "IPR004807 (11.2%) IPR027417 (11.2%) IPR001650 (11.2%)" "UvrABC system, subunit B (11.2%) P-loop containing nucleoside triphosphate hydrolase (11.2%) Helicase, C-terminal domain-like (11.2%)" VAGVTSVATSGAPGSSTSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.4%) IPR012910 (14.4%) IPR023996 (14.4%)" "Carboxypeptidase-like, regulatory domain superfamily (14.4%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" YNEAVQNYNQTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" DVTSATDYALLQNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.1%) IPR023996 (13.1%) IPR023997 (13.1%)" "TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.1%)" LFDEVEYVWPR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006094 (31.2%) GO:0005737 (31.2%) "GO:0004736 (31.2%) GO:0003824 (6.5%)" gluconeogenesis (31.2%) cytoplasm (31.2%) "pyruvate carboxylase activity (31.2%) catalytic activity (6.5%)" "IPR000891 (21.8%) IPR003379 (21.8%) IPR013785 (20.3%)" "Pyruvate carboxyltransferase (21.8%) Carboxylase, conserved domain (21.8%) Aldolase-type TIM barrel (20.3%)" AEYVLFEEALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015012 (25%) GO:0050650 (25%)" GO:0016020 (25%) GO:0030158 (25%) "heparan sulfate proteoglycan biosynthetic process (25%) chondroitin sulfate proteoglycan biosynthetic process (25%)" membrane (25%) protein xylosyltransferase activity (25%) "IPR003406 (50%) IPR043538 (50%)" "Glycosyl transferase, family 14 (50%) Xylosyltransferase (50%)" LGWGQTGNANLGAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.7%) IPR039426 (14.7%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.7%) TonB-dependent receptor-like (14.7%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" NLNNVNAVYMLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) VADGELTAVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" LFALAQALEEGYTLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (57.5%) 6.3.4.16 (42.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (57.5%) carbamoyl-phosphate synthase (ammonia) (42.5%)" "GO:0006221 (13.7%) GO:0006541 (13.7%) GO:0006526 (13.5%)" GO:0005737 (13.7%) "GO:0004088 (13.7%) GO:0005524 (13.7%) GO:0046872 (13.7%)" "pyrimidine nucleotide biosynthetic process (13.7%) glutamine metabolic process (13.7%) L-arginine biosynthetic process (13.5%)" cytoplasm (13.7%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.7%) ATP binding (13.7%) metal ion binding (13.7%)" "IPR005480 (10.3%) IPR005479 (10.1%) IPR011761 (10.1%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.3%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%)" YAPMFQLGEDKTEYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.3%) "GO:0046872 (25.2%) GO:0051539 (25.2%) GO:0004333 (22.3%)" tricarboxylic acid cycle (24.3%) "metal ion binding (25.2%) 4 iron, 4 sulfur cluster binding (25.2%) fumarate hydratase activity (22.3%)" "IPR004646 (21.1%) IPR051208 (21.1%) IPR004647 (20.3%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (21.1%) Class-I Fumarase/Tartrate Dehydratase (21.1%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (20.3%)" QYLGDGVVAGSATLAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.-.-.- (100%) Ligases (100%) "GO:0015977 (22.1%) GO:0006633 (9.1%)" GO:0009317 (22.1%) "GO:0004658 (23.4%) GO:0003989 (22.1%) GO:0016740 (1.3%)" "carbon fixation (22.1%) fatty acid biosynthetic process (9.1%)" acetyl-CoA carboxylase complex (22.1%) "propionyl-CoA carboxylase activity (23.4%) acetyl-CoA carboxylase activity (22.1%) transferase activity (1.3%)" "IPR011762 (18.8%) IPR011763 (18.8%) IPR034733 (18.8%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.8%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.8%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.8%)" FDKAAEEGDLAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) GO:0005737 (25%) "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) cytoplasm (25%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR018236 (50%) IPR028923 (50%)" "SAICAR synthetase, conserved site (50%) SAICAR synthetase/ADE2, N-terminal (50%)" SVDFDDTLLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NESCGGHFREEYQTEEGEAK Pseudomonadati Bacteria Pseudomonadati "1.3.5.1 (99.4%) 1.-.-.- (0.6%)" "succinate dehydrogenase (99.4%) Oxidoreductases (0.6%)" GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (17.2%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (17.2%)" "IPR015939 (14.5%) IPR037099 (14.5%) IPR030664 (14.4%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.5%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (14.5%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%)" FLPSLPGYVYAVK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.185 (100%) non-reducing end beta-L-arabinofuranosidase (100%) "GO:0005975 (55.6%) GO:0006508 (0.4%)" "GO:0016787 (39.8%) GO:0102478 (2.7%) GO:0016798 (0.8%)" "carbohydrate metabolic process (55.6%) proteolysis (0.4%)" "hydrolase activity (39.8%) beta-L-arabinofuranosidase activity (2.7%) hydrolase activity, acting on glycosyl bonds (0.8%)" "IPR012878 (17.4%) IPR049046 (17.4%) IPR049174 (17.4%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like (17.4%)" MTTPLVEMDGDEMTR Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.2%) GO:0006102 (20.2%) GO:0006739 (0.1%)" "GO:0004450 (20.2%) GO:0000287 (19%) GO:0051287 (19%)" "tricarboxylic acid cycle (20.2%) isocitrate metabolic process (20.2%) NADP+ metabolic process (0.1%)" "isocitrate dehydrogenase (NADP+) activity (20.2%) magnesium ion binding (19%) NAD binding (19%)" "IPR004790 (34%) IPR024084 (34%) IPR019818 (32%)" "Isocitrate dehydrogenase NADP-dependent (34%) Isopropylmalate dehydrogenase-like domain (34%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32%)" WLSLDFNGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006826 (34.6%) GO:0009279 (65.4%) iron ion transport (34.6%) cell outer membrane (65.4%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VSFFLLDEADR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.4.13 (56.3%) 3.6.4.- (43.8%)" "RNA helicase (56.3%) Acting on ATP; involved in cellular and subcellular movement (43.8%)" GO:0005829 (20%) "GO:0003676 (20%) GO:0003724 (20%) GO:0005524 (20%)" cytosol (20%) "nucleic acid binding (20%) RNA helicase activity (20%) ATP binding (20%)" "IPR000629 (14.4%) IPR001650 (14.4%) IPR011545 (14.4%)" "ATP-dependent RNA helicase DEAD-box, conserved site (14.4%) Helicase, C-terminal domain-like (14.4%) DEAD/DEAH-box helicase domain (14.4%)" NLASNLETLSLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (100%) cytoplasm (100%) "IPR007557 (50%) IPR047767 (50%)" "PSP1, C-terminal (50%) PSP1-like (50%)" HLDMNLVNAQQAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.2%) "GO:0003677 (25.2%) GO:0003917 (25.2%) GO:0046872 (24.4%)" DNA topological change (25.2%) "DNA binding (25.2%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.2%) metal ion binding (24.4%)" "IPR000380 (7.3%) IPR003601 (7.3%) IPR006171 (7.3%)" "DNA topoisomerase, type IA (7.3%) DNA topoisomerase, type IA, domain 2 (7.3%) TOPRIM domain (7.3%)" SNQAEMQNLVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0004521 (50%) GO:0016787 (50%)" "RNA endonuclease activity (50%) hydrolase activity (50%)" "IPR005229 (33.3%) IPR013527 (33.3%) IPR013551 (33.3%)" "Endoribonuclease YicC/YloC-like (33.3%) Endoribonuclease YicC-like, N-terminal (33.3%) Endoribonuclease YicC-like, C-terminal (33.3%)" LGFLAGPEWLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.- (100%) Transaminases (100%) GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004838 (16.7%) IPR004839 (16.7%) IPR015421 (16.7%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.7%) Aminotransferase, class I/classII, large domain (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" FLGHPDMR Bacteria Bacteria "7.1.1.- (71.3%) 1.6.5.11 (17.2%) 1.6.5.9 (5.7%)" "Hydron translocation or charge separation linked to oxidoreductase reactions (71.3%) Transferred entry: 1.6.5.9 (17.2%) NADH:ubiquinone reductase (non-electrogenic) (5.7%)" "GO:0005886 (18.8%) GO:0030964 (8%) GO:0005737 (7.7%)" "GO:0008137 (18.9%) GO:0048038 (18.9%) GO:0051287 (18.3%)" "plasma membrane (18.8%) NADH dehydrogenase complex (8%) cytoplasm (7.7%)" "NADH dehydrogenase (ubiquinone) activity (18.9%) quinone binding (18.9%) NAD binding (18.3%)" "IPR001268 (17.1%) IPR037232 (17%) IPR001135 (16.5%)" "NADH:ubiquinone oxidoreductase, 30kDa subunit (17.1%) NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily (17%) NADH-quinone oxidoreductase, subunit D (16.5%)" FMTTKPSNVGLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (49.6%) "GO:0003824 (34.8%) GO:0016787 (14.2%) GO:0004556 (1.4%)" carbohydrate metabolic process (49.6%) "catalytic activity (34.8%) hydrolase activity (14.2%) alpha-amylase activity (1.4%)" "IPR004300 (33.7%) IPR052046 (33.7%) IPR011330 (32.7%)" "Glycoside hydrolase family 57, N-terminal domain (33.7%) Glycosyl hydrolase family 57 (33.7%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.7%)" EAGQLAGLNVQR Bacteria Bacteria GO:0005737 (0.4%) "GO:0005524 (33.5%) GO:0140662 (33.5%) GO:0051082 (32.6%)" cytoplasm (0.4%) "ATP binding (33.5%) ATP-dependent protein folding chaperone (33.5%) unfolded protein binding (32.6%)" "IPR013126 (16.9%) IPR018181 (16.9%) IPR043129 (16.9%)" "Heat shock protein 70 family (16.9%) Heat shock protein 70, conserved site (16.9%) ATPase, nucleotide binding domain (16.9%)" ASVVGSLAQTTGEVLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (9.1%) GO:0009279 (81.8%) GO:0015344 (9.1%) siderophore transmembrane transport (9.1%) cell outer membrane (81.8%) siderophore uptake transmembrane transporter activity (9.1%) "IPR012910 (15.8%) IPR023997 (15.8%) IPR039426 (15.8%)" "TonB-dependent receptor, plug domain (15.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.8%) TonB-dependent receptor-like (15.8%)" DQNELDGLNGQLNNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.6%) "GO:0009279 (26.3%) GO:0046930 (24.6%)" GO:0015288 (24.6%) monoatomic ion transport (24.6%) "cell outer membrane (26.3%) pore complex (24.6%)" porin activity (24.6%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" GDFAHELFGELVK Bacteroidota Bacteria Pseudomonadati Bacteroidota "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (77.1%) GO:0008675 (11.4%) GO:0008700 (11.4%)" "lyase activity (77.1%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (11.4%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (11.4%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" AEFFLPLMVNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016740 (100%) transferase activity (100%) "IPR029044 (86.4%) IPR005835 (13.6%)" "Nucleotide-diphospho-sugar transferases (86.4%) Nucleotidyl transferase domain (13.6%)" TGERGDLALYNAEQEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (25.1%) IPR011322 (25.1%) IPR015867 (25.1%)" "Nitrogen regulatory protein PII (25.1%) Nitrogen regulatory PII-like, alpha/beta (25.1%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25.1%)" VNVDAGALMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri QSSTEGMVLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.21 (66.7%) 3.2.1.74 (33.3%)" "beta-glucosidase (66.7%) glucan 1,4-beta-glucosidase (33.3%)" GO:0005975 (50%) "GO:0004553 (48%) GO:0008422 (1%) GO:0031217 (1%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48%) beta-glucosidase activity (1%) glucan 1,4-beta-glucosidase activity (1%)" "IPR001764 (12.7%) IPR050288 (12.7%) IPR002772 (12.4%)" "Glycoside hydrolase, family 3, N-terminal (12.7%) Cellulose-degrading glycosyl hydrolase 3 (12.7%) Glycoside hydrolase family 3 C-terminal domain (12.4%)" SANYYVQQLYGENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17.1%) IPR010720 (17.1%) IPR051563 (17.1%)" "Carbohydrate-binding, CenC-like (17.1%) Alpha-L-arabinofuranosidase, C-terminal (17.1%) Glycosyl Hydrolase Family 51 (17.1%)" LSDGSLGLGKLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) KVNLTYTDLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0006432 (16.3%) GO:0006412 (0.4%)" "GO:0009328 (16.3%) GO:0005737 (0.4%)" "GO:0000049 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" "phenylalanyl-tRNA aminoacylation (16.3%) translation (0.4%)" "phenylalanine-tRNA ligase complex (16.3%) cytoplasm (0.4%)" "tRNA binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005121 (8%) IPR002547 (7.8%) IPR004532 (7.8%)" "Ferrodoxin-fold anticodon-binding domain (8%) tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%)" LSVNDSNMNYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" MLLLNNNYLGNVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (13.9%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (13.9%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.3%) IPR012000 (12.3%) IPR012001 (12.3%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.3%) Thiamine pyrophosphate enzyme, central domain (12.3%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.3%)" LLGQGNAPLTVDGSFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007645 (8.3%) IPR015712 (8.3%) IPR019462 (8.3%)" "RNA polymerase Rpb2, domain 3 (8.3%) DNA-directed RNA polymerase, subunit 2 (8.3%) DNA-directed RNA polymerase, beta subunit, external 1 domain (8.3%)" GVFEDQQLAKEELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (50%) IPR027417 (50%)" "Tetraacyldisaccharide 4'-kinase (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" YMNPWAGFYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" DYMGNVMVNFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TGNPHFVYDSYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" VNDLYPADVDNDQLEGLLTTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) "GO:0003824 (36.8%) GO:0016787 (13.2%)" carbohydrate metabolic process (50%) "catalytic activity (36.8%) hydrolase activity (13.2%)" "IPR004300 (33.9%) IPR052046 (33.9%) IPR011330 (32.1%)" "Glycoside hydrolase family 57, N-terminal domain (33.9%) Glycosyl hydrolase family 57 (33.9%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.1%)" KADLTGSVAVVSTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (5.6%) GO:0009279 (88.9%) GO:0015344 (5.6%) siderophore transmembrane transport (5.6%) cell outer membrane (88.9%) siderophore uptake transmembrane transporter activity (5.6%) "IPR012910 (12.8%) IPR023997 (12.8%) IPR037066 (12.8%)" "TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.8%) TonB-dependent receptor, plug domain superfamily (12.8%)" VSATLVNLNHWDSSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri HNANGDPQNYWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25.6%) IPR035376 (25.6%) IPR038143 (24.4%)" "NigD-like N-terminal OB domain (25.6%) NigD-like, C-terminal domain (25.6%) NigD-like, C-terminal domain superfamily (24.4%)" YYDDVMR root "2.7.7.8 (97.6%) 5.4.3.8 (2.4%)" "polyribonucleotide nucleotidyltransferase (97.6%) glutamate-1-semialdehyde 2,1-aminomutase (2.4%)" "GO:0006396 (11.9%) GO:0006402 (11.9%) GO:0007018 (1.6%)" "GO:0005829 (11.9%) GO:0000922 (1.6%) GO:0005828 (1.6%)" "GO:0000175 (11.9%) GO:0000287 (11.9%) GO:0003723 (11.9%)" "RNA processing (11.9%) mRNA catabolic process (11.9%) microtubule-based movement (1.6%)" "cytosol (11.9%) spindle pole (1.6%) kinetochore microtubule (1.6%)" "3'-5'-RNA exonuclease activity (11.9%) magnesium ion binding (11.9%) RNA binding (11.9%)" "IPR001247 (7.3%) IPR003029 (7.3%) IPR004087 (7.3%)" "Exoribonuclease, phosphorolytic domain 1 (7.3%) S1 domain (7.3%) K Homology domain (7.3%)" QYNVNVSGGTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006826 (34.6%) GO:0009279 (65.4%) iron ion transport (34.6%) cell outer membrane (65.4%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DQVPDGPELQNLLQFLESSEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (30.6%) GO:0008610 (4.1%)" GO:0016020 (30.6%) GO:0008780 (34.7%) "lipid A biosynthetic process (30.6%) lipid biosynthetic process (4.1%)" membrane (30.6%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.7%) "IPR010137 (20.2%) IPR011004 (20.2%) IPR029098 (20.2%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.2%) Trimeric LpxA-like superfamily (20.2%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.2%)" YADGLMVFDDTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.9%) IPR004634 (16.9%) IPR004635 (16.9%)" "Peptidase S49 (16.9%) Peptidase S49, protease IV (16.9%) Peptidase S49, SppA (16.9%)" LVQNQDVFTEFMLASR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.5.1.7 (100%) saccharopine dehydrogenase (NAD(+), L-lysine-forming) (100%) GO:0004754 (100%) saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (100%) "IPR005097 (33.3%) IPR032095 (33.3%) IPR036291 (33.3%)" "Saccharopine dehydrogenase, NADP binding domain (33.3%) Saccharopine dehydrogenase-like, C-terminal (33.3%) NAD(P)-binding domain superfamily (33.3%)" VAFEFAMK root 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) GO:0009098 (19.7%) "GO:0005829 (19.7%) GO:0016020 (1.5%)" "GO:0000287 (19.7%) GO:0003862 (19.7%) GO:0051287 (19.7%)" L-leucine biosynthetic process (19.7%) "cytosol (19.7%) membrane (1.5%)" "magnesium ion binding (19.7%) 3-isopropylmalate dehydrogenase activity (19.7%) NAD binding (19.7%)" "IPR004429 (31.7%) IPR019818 (31.7%) IPR024084 (31.7%)" "Isopropylmalate dehydrogenase (31.7%) Isocitrate/isopropylmalate dehydrogenase, conserved site (31.7%) Isopropylmalate dehydrogenase-like domain (31.7%)" LGFEGGQMPLQR root GO:0006412 (25.2%) "GO:0022625 (25.2%) GO:0005840 (0%)" "GO:0003735 (25.2%) GO:0019843 (24.3%)" translation (25.2%) "cytosolic large ribosomal subunit (25.2%) ribosome (0%)" "structural constituent of ribosome (25.2%) rRNA binding (24.3%)" "IPR005749 (20.4%) IPR030878 (20.4%) IPR021131 (20.3%)" "Large ribosomal subunit protein uL15, bacteria (20.4%) Large ribosomal subunit protein uL15 (20.4%) Large ribosomal subunit protein uL15/eL18 (20.3%)" VNFNTTNSLQTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (7.4%) GO:0009279 (85.2%) GO:0015344 (7.4%) siderophore transmembrane transport (7.4%) cell outer membrane (85.2%) siderophore uptake transmembrane transporter activity (7.4%) "IPR012910 (12.1%) IPR023997 (12.1%) IPR039426 (12.1%)" "TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.1%) TonB-dependent receptor-like (12.1%)" HGSNTNESSTNYDLFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" EALKPVMEWLYYSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (20.9%) GO:0009099 (20.9%)" "GO:0004455 (20.9%) GO:0046872 (20.9%) GO:0016853 (16.3%)" "isoleucine biosynthetic process (20.9%) L-valine biosynthetic process (20.9%)" "ketol-acid reductoisomerase activity (20.9%) metal ion binding (20.9%) isomerase activity (16.3%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" LVDMNLSVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011260 (16.7%) IPR011262 (16.7%) IPR011263 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (16.7%) DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%)" VLADFLEK root "2.7.7.8 (80.6%) 2.1.1.- (2.8%) 2.7.1.180 (2.8%)" "polyribonucleotide nucleotidyltransferase (80.6%) Methyltransferases (2.8%) FAD:protein FMN transferase (2.8%)" "GO:0006402 (8.6%) GO:0006396 (8.3%) GO:0090251 (2.4%)" "GO:0005829 (9.4%) GO:0005737 (3.2%) GO:0005634 (2.7%)" "GO:0000287 (8.8%) GO:0003723 (8.8%) GO:0000175 (8.6%)" "mRNA catabolic process (8.6%) RNA processing (8.3%) protein localization involved in establishment of planar polarity (2.4%)" "cytosol (9.4%) cytoplasm (3.2%) nucleus (2.7%)" "magnesium ion binding (8.8%) RNA binding (8.8%) 3'-5'-RNA exonuclease activity (8.6%)" "IPR053351 (14.1%) IPR001247 (4.4%) IPR012162 (4.4%)" "Chloroplast NDH Complex Assembly Protein (14.1%) Exoribonuclease, phosphorolytic domain 1 (4.4%) Polyribonucleotide nucleotidyltransferase (4.4%)" VLDGAVATYSAADGVQPQSETVWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0032790 (20.1%) GO:0006412 (0.2%)" GO:0005737 (19.7%) "GO:0003924 (20.1%) GO:0005525 (20.1%) GO:0003746 (19.9%)" "ribosome disassembly (20.1%) translation (0.2%)" cytoplasm (19.7%) "GTPase activity (20.1%) GTP binding (20.1%) translation elongation factor activity (19.9%)" "IPR000795 (6.4%) IPR005225 (6.4%) IPR031157 (6.4%)" "Translational (tr)-type GTP-binding domain (6.4%) Small GTP-binding domain (6.4%) Tr-type G domain, conserved site (6.4%)" TFFNVEDLGDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.3.11 (100%) N-succinylornithine carbamoyltransferase (100%) "GO:0019240 (23.8%) GO:0042450 (23.8%) GO:0006520 (1.6%)" "GO:0016597 (25.4%) GO:0004585 (23.8%) GO:0016743 (1.6%)" "citrulline biosynthetic process (23.8%) L-arginine biosynthetic process via ornithine (23.8%) amino acid metabolic process (1.6%)" "amino acid binding (25.4%) ornithine carbamoyltransferase activity (23.8%) carboxyl- or carbamoyltransferase activity (1.6%)" "IPR006131 (20.3%) IPR006132 (20.3%) IPR036901 (20.3%)" "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.3%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20.3%) Aspartate/ornithine carbamoyltransferase superfamily (20.3%)" GSVMPTYREDWAFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" GPLENYSDREDCMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" LNPQQFVQMLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.8%) GO:0016020 (0.4%)" "GO:0008658 (11.2%) GO:0008955 (11.2%) GO:0004180 (10.8%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.8%) membrane (0.4%)" "penicillin binding (11.2%) peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.8%)" "IPR001264 (17%) IPR001460 (17%) IPR050396 (17%)" "Glycosyl transferase, family 51 (17%) Penicillin-binding protein, transpeptidase (17%) Glycosyltransferase 51/Transpeptidase (17%)" AGAETVQLYLHDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" YNLYPLPNTELTANPNLHNDNY Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" MPLGVMVTLR root GO:0006412 (17%) "GO:0005840 (17%) GO:1990904 (16.9%) GO:0009536 (0.1%)" "GO:0003735 (17%) GO:0019843 (16%) GO:0000049 (15.9%)" translation (17%) "ribosome (17%) ribonucleoprotein complex (16.9%) plastid (0.1%)" "structural constituent of ribosome (17%) rRNA binding (16%) tRNA binding (15.9%)" "IPR002132 (19.6%) IPR031309 (19.6%) IPR031310 (19.6%)" "Large ribosomal subunit protein uL5 (19.6%) Large ribosomal subunit protein uL5, C-terminal (19.6%) Large ribosomal subunit protein uL5, N-terminal (19.6%)" DDSFTLFGFATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006281 (12%) GO:0006310 (12%)" "GO:0005737 (12%) GO:0009379 (12%) GO:0048476 (11.3%)" "GO:0005524 (12%) GO:0009378 (12%) GO:0000400 (11.3%)" "DNA repair (12%) DNA recombination (12%)" "cytoplasm (12%) Holliday junction helicase complex (12%) Holliday junction resolvase complex (11.3%)" "ATP binding (12%) four-way junction helicase activity (12%) four-way junction DNA binding (11.3%)" "IPR000085 (14.3%) IPR003583 (14.3%) IPR010994 (14.3%)" "Holliday junction branch migration complex subunit RuvA (14.3%) Helix-hairpin-helix DNA-binding motif, class 1 (14.3%) RuvA domain 2-like (14.3%)" VELALALGK Bacteria Bacteria "2.5.1.75 (50%) 1.-.-.- (25%) 6.1.1.17 (25%)" "tRNA dimethylallyltransferase (50%) Oxidoreductases (25%) glutamate--tRNA ligase (25%)" "GO:0006400 (3.3%) GO:0006424 (3.3%)" GO:0005829 (10%) "GO:0016757 (36.7%) GO:0003677 (6.7%) GO:0003700 (6.7%)" "tRNA modification (3.3%) glutamyl-tRNA aminoacylation (3.3%)" cytosol (10%) "glycosyltransferase activity (36.7%) DNA binding (6.7%) DNA-binding transcription factor activity (6.7%)" "IPR000836 (28.3%) IPR029057 (26.7%) IPR000415 (3.3%)" "Phosphoribosyltransferase domain (28.3%) Phosphoribosyltransferase-like (26.7%) Nitroreductase-like (3.3%)" TLASQMADAQLEK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.3%) "GO:0003677 (25.3%) GO:0003917 (25.3%) GO:0046872 (24.1%)" DNA topological change (25.3%) "DNA binding (25.3%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.3%) metal ion binding (24.1%)" "IPR000380 (7.4%) IPR003602 (7.4%) IPR013497 (7.4%)" "DNA topoisomerase, type IA (7.4%) DNA topoisomerase, type IA, DNA-binding domain (7.4%) DNA topoisomerase, type IA, central (7.4%)" DHANDDGTVVPVELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR035986 (100%) PKD domain superfamily (100%) DAQLKDLEAALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (25.9%) GO:0030313 (24.1%) "GO:0016209 (24.1%) GO:0016491 (24.1%) GO:0004601 (1.7%)" cytochrome complex assembly (25.9%) cell envelope (24.1%) "antioxidant activity (24.1%) oxidoreductase activity (24.1%) peroxidase activity (1.7%)" "IPR000866 (25.4%) IPR025380 (25.4%) IPR050553 (25.4%)" "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant (25.4%) Domain of unknown function DUF4369 (25.4%) Thioredoxin family ResA/DsbE subfamily (25.4%)" LEDVTAELK root 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (23.9%) GO:0019877 (23.9%)" GO:0016020 (4.4%) "GO:0000166 (23.9%) GO:0047850 (23.9%)" "lysine biosynthetic process via diaminopimelate (23.9%) diaminopimelate biosynthetic process (23.9%)" membrane (4.4%) "nucleotide binding (23.9%) diaminopimelate dehydrogenase activity (23.9%)" "IPR000683 (23.3%) IPR010190 (23.3%) IPR032094 (23.3%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (23.3%) Diaminopimelate dehydrogenase, Ddh (23.3%) Meso-diaminopimelate D-dehydrogenase, C-terminal (23.3%)" DWEADGVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0045493 (38.2%) GO:0000272 (11.8%)" "GO:0004553 (38.2%) GO:0031176 (11.8%)" "xylan catabolic process (38.2%) polysaccharide catabolic process (11.8%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (38.2%) endo-1,4-beta-xylanase activity (11.8%)" "IPR001000 (29.3%) IPR017853 (27.6%) IPR044846 (27.6%)" "Glycoside hydrolase family 10 domain (29.3%) Glycoside hydrolase superfamily (27.6%) Glycoside hydrolase family 10 (27.6%)" EMLATGLK root "7.1.2.2 (98.6%) 6.3.2.10 (1.4%)" "H(+)-transporting two-sector ATPase (98.6%) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (1.4%)" "GO:0009166 (0.6%) GO:0000398 (0.3%) GO:0006396 (0.3%)" "GO:0005886 (20.9%) GO:0045259 (20.9%) GO:0005737 (0.6%)" "GO:0005524 (21.2%) GO:0046933 (20.9%) GO:0016787 (8.2%)" "nucleotide catabolic process (0.6%) mRNA splicing, via spliceosome (0.3%) RNA processing (0.3%)" "plasma membrane (20.9%) proton-transporting ATP synthase complex (20.9%) cytoplasm (0.6%)" "ATP binding (21.2%) proton-transporting ATP synthase activity, rotational mechanism (20.9%) hydrolase activity (8.2%)" "IPR027417 (9.6%) IPR004100 (9.5%) IPR036121 (9.5%)" "P-loop containing nucleoside triphosphate hydrolase (9.6%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (9.5%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily (9.5%)" AGCDVNALEAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0016485 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) protein processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000209 (16.1%) IPR022398 (16.1%) IPR023828 (16.1%)" "Peptidase S8/S53 domain (16.1%) Peptidase S8, subtilisin, His-active site (16.1%) Peptidase S8, subtilisin, Ser-active site (16.1%)" LPEGNDYEQAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.2.1.1 (96.6%) 2.2.1.- (3.4%)" "transketolase (96.6%) Transketolases and transaldolases (3.4%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005474 (12.7%) IPR005475 (12.7%) IPR009014 (12.7%)" "Transketolase, N-terminal (12.7%) Transketolase-like, pyrimidine-binding domain (12.7%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.7%)" RLLCNLLGNDVEK Pseudomonadati Bacteria Pseudomonadati 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (51.2%) IPR032466 (48.8%)" "Uronate isomerase (51.2%) Metal-dependent hydrolase (48.8%)" SLVDGMDYFELAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (11.1%) GO:0009279 (88.9%) iron ion transport (11.1%) cell outer membrane (88.9%) "IPR036942 (14%) IPR039426 (14%) IPR008969 (13.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14%) TonB-dependent receptor-like (14%) Carboxypeptidase-like, regulatory domain superfamily (13.2%)" TVPGLTELVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.4%) GO:0005829 (32.4%) "GO:0008926 (32.4%) GO:0009026 (2.9%)" mannitol catabolic process (32.4%) cytosol (32.4%) "mannitol-1-phosphate 5-dehydrogenase activity (32.4%) tagaturonate reductase activity (2.9%)" "IPR013118 (21.8%) IPR013131 (21.8%) IPR008927 (18.8%)" "Mannitol dehydrogenase, C-terminal (21.8%) Mannitol dehydrogenase, N-terminal (21.8%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.8%)" TAYTLMPELGYEFNNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027385 (52.9%) IPR011250 (47.1%)" "Outer membrane protein, beta-barrel domain (52.9%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (47.1%)" SNNLYNVLDASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YFADDDAFCER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0030170 (100%) pyridoxal phosphate binding (100%) "IPR001608 (33.6%) IPR011078 (33.6%) IPR029066 (32.8%)" "Alanine racemase, N-terminal (33.6%) Pyridoxal phosphate homeostasis protein (33.6%) PLP-binding barrel (32.8%)" ASNAPELFAKPNLDGGLLGGASLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.6%) GO:0006096 (12.6%) GO:0019563 (12.6%)" "GO:0005829 (12.6%) GO:0016020 (12.1%)" GO:0004807 (12.6%) "gluconeogenesis (12.6%) glycolytic process (12.6%) glycerol catabolic process (12.6%)" "cytosol (12.6%) membrane (12.1%)" triose-phosphate isomerase activity (12.6%) "IPR000652 (17.1%) IPR020861 (17.1%) IPR022896 (17.1%)" "Triosephosphate isomerase (17.1%) Triosephosphate isomerase, active site (17.1%) Triosephosphate isomerase, bacterial/eukaryotic (17.1%)" HNLNLMGGYTMER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" HGASCPLGMGVSCSADR root 4.2.1.2 (100%) fumarate hydratase (100%) "GO:0006099 (21.1%) GO:0006091 (0.1%) GO:0006106 (0.1%)" GO:0016020 (0.1%) "GO:0046872 (21.4%) GO:0051539 (21.4%) GO:0004333 (21.1%)" "tricarboxylic acid cycle (21.1%) generation of precursor metabolites and energy (0.1%) fumarate metabolic process (0.1%)" membrane (0.1%) "metal ion binding (21.4%) 4 iron, 4 sulfur cluster binding (21.4%) fumarate hydratase activity (21.1%)" "IPR004646 (19%) IPR051208 (19%) IPR004647 (18.9%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (19%) Class-I Fumarase/Tartrate Dehydratase (19%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.9%)" LFQALALAR root 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.4%) GO:0000053 (16.4%) GO:0006526 (16.4%)" "GO:0005737 (16.4%) GO:0005680 (0.1%)" "GO:0005524 (16.7%) GO:0004055 (16.4%) GO:0016740 (0.6%)" "urea cycle (16.4%) argininosuccinate metabolic process (16.4%) L-arginine biosynthetic process (16.4%)" "cytoplasm (16.4%) anaphase-promoting complex (0.1%)" "ATP binding (16.7%) argininosuccinate synthase activity (16.4%) transferase activity (0.6%)" "IPR001518 (14.1%) IPR048267 (14.1%) IPR014729 (14.1%)" "Argininosuccinate synthase (14.1%) Arginosuccinate synthase-like, N-terminal domain (14.1%) Rossmann-like alpha/beta/alpha sandwich fold (14.1%)" LEVFLLR root "2.4.99.17 (97.9%) 5.-.-.- (1%) 2.1.1.72 (0.2%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase (97.9%) Isomerases (1%) site-specific DNA-methyltransferase (adenine-specific) (0.2%)" "GO:0002099 (27.9%) GO:0000463 (0.6%) GO:0000466 (0.6%)" "GO:0005737 (28%) GO:0016020 (0.9%) GO:0005886 (0.7%)" "GO:0051075 (27.9%) GO:0046872 (0.8%) GO:0016818 (0.7%)" "tRNA wobble guanine modification (27.9%) maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.6%) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.6%)" "cytoplasm (28%) membrane (0.9%) plasma membrane (0.7%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (27.9%) metal ion binding (0.8%) hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (0.7%)" "IPR003699 (21.4%) IPR036100 (21.3%) IPR042118 (21.2%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA (21.4%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily (21.3%) QueA, domain 1 (21.2%)" VAQLVDGLTK Bacteria Bacteria "2.7.6.5 (93.8%) 3.1.7.2 (6.3%)" "GTP diphosphokinase (93.8%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (6.3%)" "GO:0015969 (29.8%) GO:0015970 (4.3%) GO:0015949 (2.4%)" GO:0005886 (33.7%) "GO:0016301 (8.7%) GO:0008728 (6.7%) GO:0016787 (6.3%)" "guanosine tetraphosphate metabolic process (29.8%) guanosine tetraphosphate biosynthetic process (4.3%) nucleobase-containing small molecule interconversion (2.4%)" plasma membrane (33.7%) "kinase activity (8.7%) GTP diphosphokinase activity (6.7%) hydrolase activity (6.3%)" "IPR003607 (9.4%) IPR004095 (9.4%) IPR007685 (9.4%)" "HD/PDEase domain (9.4%) TGS (9.4%) RelA/SpoT (9.4%)" KNTPYAAQMAAEDCAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (19.9%) "GO:0005840 (20.3%) GO:1990904 (19.9%)" "GO:0003735 (19.9%) GO:0019843 (19.9%)" translation (19.9%) "ribosome (20.3%) ribonucleoprotein complex (19.9%)" "structural constituent of ribosome (19.9%) rRNA binding (19.9%)" "IPR001971 (25%) IPR018102 (25%) IPR019981 (25%)" "Small ribosomal subunit protein uS11 (25%) Small ribosomal subunit protein uS11, conserved site (25%) Small ribosomal subunit protein uS11, bacteria (25%)" HCLENGLDDVDFLVQNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" NSSLYHLDFSFDEQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.2%) GO:0006164 (1.4%)" GO:0005737 (20.5%) "GO:0004642 (20.5%) GO:0005524 (19.2%) GO:0046872 (19.2%)" "'de novo' IMP biosynthetic process (19.2%) purine nucleotide biosynthetic process (1.4%)" cytoplasm (20.5%) "phosphoribosylformylglycinamidine synthase activity (20.5%) ATP binding (19.2%) metal ion binding (19.2%)" "IPR010918 (11.4%) IPR036676 (11.4%) IPR036921 (11.4%)" "PurM-like, C-terminal domain (11.4%) PurM-like, C-terminal domain superfamily (11.4%) PurM-like, N-terminal domain superfamily (11.4%)" MHPVDSNELSFMLAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25.3%) "GO:0005525 (25.3%) GO:0003746 (24.9%) GO:0003924 (24.5%)" ribosome disassembly (25.3%) "GTP binding (25.3%) translation elongation factor activity (24.9%) GTPase activity (24.5%)" "IPR000640 (7.9%) IPR005517 (7.9%) IPR035649 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translation elongation factor EFG/EF2, domain IV (7.9%) EFG, domain V (7.9%)" EGTVVDADDLMAEMLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25.4%) GO:0005737 (23.9%) "GO:0004814 (25.4%) GO:0005524 (25.4%)" arginyl-tRNA aminoacylation (25.4%) cytoplasm (23.9%) "arginine-tRNA ligase activity (25.4%) ATP binding (25.4%)" "IPR001278 (13.1%) IPR035684 (13.1%) IPR008909 (12.8%)" "Arginine-tRNA ligase (13.1%) Arginyl-tRNA synthetase, catalytic core domain (13.1%) DALR anticodon binding (12.8%)" SLGLTYTDMGGDTNFLEELER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" APTDNDYGASLQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.9%) IPR006102 (7.9%) IPR006103 (7.9%)" "Beta galactosidase small chain/ domain 5 (7.9%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.9%) Glycoside hydrolase family 2, catalytic domain (7.9%)" FGELHLLYNDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0017004 (33.3%) GO:0005886 (33.3%) GO:0020037 (33.3%) cytochrome complex assembly (33.3%) plasma membrane (33.3%) heme binding (33.3%) "IPR002541 (32.7%) IPR007816 (32.7%) IPR045062 (32.7%)" "Cytochrome c assembly protein (32.7%) ResB-like domain (32.7%) Cytochrome c-type biogenesis protein CcsA/CcmC (32.7%)" VGSFDAGFGSSYLAR Bacteria Bacteria 4.1.3.36 (100%) 1,4-dihydroxy-2-naphthoyl-CoA synthase (100%) "GO:0009234 (32.4%) GO:0042372 (2.9%)" GO:0005829 (32.4%) GO:0008935 (32.4%) "menaquinone biosynthetic process (32.4%) phylloquinone biosynthetic process (2.9%)" cytosol (32.4%) 1,4-dihydroxy-2-naphthoyl-CoA synthase activity (32.4%) "IPR001753 (20.4%) IPR029045 (20.4%) IPR014748 (20.3%)" "Enoyl-CoA hydratase/isomerase (20.4%) ClpP/crotonase-like domain superfamily (20.4%) Enoyl-CoA hydratase, C-terminal (20.3%)" MSEAMNNYLTAYYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" ADLPENLKEQLLVELYSK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0042274 (19.9%) GO:0006412 (19.7%)" "GO:0015935 (19.7%) GO:0005840 (0.4%) GO:1990904 (0.1%)" "GO:0003735 (19.9%) GO:0019843 (19.9%) GO:0003723 (0.4%)" "ribosomal small subunit biogenesis (19.9%) translation (19.7%)" "small ribosomal subunit (19.7%) ribosome (0.4%) ribonucleoprotein complex (0.1%)" "structural constituent of ribosome (19.9%) rRNA binding (19.9%) RNA binding (0.4%)" "IPR036986 (17%) IPR001912 (16.6%) IPR002942 (16.6%)" "RNA-binding S4 domain superfamily (17%) Small ribosomal subunit protein uS4, N-terminal (16.6%) RNA-binding S4 domain (16.6%)" AWGYYTDDPSDPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" LTLETQDQESNQEFDEEVLHMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011260 (16.7%) IPR011262 (16.7%) IPR011263 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (16.7%) DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%)" VSAVLDPVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.18 (100%) glutamine--tRNA ligase (100%) "GO:0006425 (24.6%) GO:0006424 (1.7%)" GO:0005829 (24.6%) "GO:0004819 (24.6%) GO:0005524 (24.6%)" "glutaminyl-tRNA aminoacylation (24.6%) glutamyl-tRNA aminoacylation (1.7%)" cytosol (24.6%) "glutamine-tRNA ligase activity (24.6%) ATP binding (24.6%)" "IPR004514 (10.5%) IPR020058 (10.5%) IPR020059 (10.5%)" "Glutamine-tRNA synthetase (10.5%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.5%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain (10.5%)" FQSVPYYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.6%) "GO:0003677 (25.6%) GO:0003917 (25.6%) GO:0046872 (23.1%)" DNA topological change (25.6%) "DNA binding (25.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.6%) metal ion binding (23.1%)" "IPR000380 (7.5%) IPR003601 (7.5%) IPR006171 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, domain 2 (7.5%) TOPRIM domain (7.5%)" AGEMTLNFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR015171 (15%) IPR006047 (14.6%) IPR019492 (14.6%)" "Cyclomaltodextrinase, N-terminal (15%) Glycosyl hydrolase family 13, catalytic domain (14.6%) Cyclo-malto-dextrinase, C-terminal (14.6%)" NGATVELPASSLNLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" LDVTVNMAYTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "Carboxypeptidase-like, regulatory domain superfamily (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" EQTSYMFLTGPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.-.-.- (100%) Ligases (100%) "GO:0015977 (22.1%) GO:0006633 (4.7%)" GO:0009317 (22.1%) "GO:0004658 (23.2%) GO:0003989 (22.1%) GO:0016740 (5.3%)" "carbon fixation (22.1%) fatty acid biosynthetic process (4.7%)" acetyl-CoA carboxylase complex (22.1%) "propionyl-CoA carboxylase activity (23.2%) acetyl-CoA carboxylase activity (22.1%) transferase activity (5.3%)" "IPR011762 (19.4%) IPR011763 (19.4%) IPR034733 (19.4%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.4%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.4%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.4%)" KASETPQVWALYK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005975 (43.8%) GO:0045493 (5.5%)" "GO:0016787 (45.2%) GO:0046559 (5.5%)" "carbohydrate metabolic process (43.8%) xylan catabolic process (5.5%)" "hydrolase activity (45.2%) alpha-glucuronidase activity (5.5%)" "IPR031924 (25%) IPR041437 (25%) IPR029018 (23.7%)" "Glycosyl hydrolase family 115 (25%) Gylcosyl hydrolase 115 C-terminal domain (25%) Beta-hexosaminidase-like, domain 2 (23.7%)" LLVPGMVER Bacteria Bacteria "1.1.1.276 (78.6%) 1.-.-.- (7.1%) 1.1.1.- (7.1%)" "serine 3-dehydrogenase (NADP(+)) (78.6%) Oxidoreductases (7.1%) With NAD(+) or NADP(+) as acceptor (7.1%)" "GO:0005576 (1.5%) GO:0016020 (1.5%)" "GO:0016616 (93.8%) GO:0016491 (3.1%)" "extracellular region (1.5%) membrane (1.5%)" "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (93.8%) oxidoreductase activity (3.1%)" "IPR002347 (35.8%) IPR036291 (35.8%) IPR020904 (24.4%)" "Short-chain dehydrogenase/reductase SDR (35.8%) NAD(P)-binding domain superfamily (35.8%) Short-chain dehydrogenase/reductase, conserved site (24.4%)" EAGVAPDLLR Bacteria Bacteria "2.5.1.49 (47.4%) 4.4.1.11 (36.8%) 2.5.1.47 (5.3%)" "O-acetylhomoserine aminocarboxypropyltransferase (47.4%) methionine gamma-lyase (36.8%) cysteine synthase (5.3%)" "GO:0006535 (13.9%) GO:0019346 (13.9%) GO:0071269 (13.9%)" GO:0005737 (13.8%) "GO:0003961 (13.9%) GO:0004124 (13.9%) GO:0030170 (13.9%)" "cysteine biosynthetic process from serine (13.9%) transsulfuration (13.9%) L-homocysteine biosynthetic process (13.9%)" cytoplasm (13.8%) "O-acetylhomoserine aminocarboxypropyltransferase activity (13.9%) cysteine synthase activity (13.9%) pyridoxal phosphate binding (13.9%)" "IPR000277 (19.9%) IPR006235 (19.9%) IPR015422 (19.9%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (19.9%) O-acetylhomoserine/O-acetylserine sulfhydrylase (19.9%) Pyridoxal phosphate-dependent transferase, small domain (19.9%)" NAEEAVFAAQMAR Pseudomonadati Bacteria Pseudomonadati 2.8.1.10 (100%) thiazole synthase (100%) "GO:0009229 (30.5%) GO:0009228 (8%)" GO:0005737 (30.2%) "GO:1990107 (23.3%) GO:0016783 (8%)" "thiamine diphosphate biosynthetic process (30.5%) thiamine biosynthetic process (8%)" cytoplasm (30.2%) "thiazole synthase activity (23.3%) sulfurtransferase activity (8%)" "IPR008867 (33.5%) IPR033983 (33.5%) IPR013785 (33.1%)" "Thiazole synthase (33.5%) Thiazole synthase ThiG (33.5%) Aldolase-type TIM barrel (33.1%)" ALLANGVLAVSEGANMPSTPEALK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006537 (26.9%) GO:0005829 (26.9%) "GO:0004354 (26.9%) GO:0000166 (19.2%)" glutamate biosynthetic process (26.9%) cytosol (26.9%) "glutamate dehydrogenase (NADP+) activity (26.9%) nucleotide binding (19.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" GWGGFVYNSAEGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.4%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.4%) "IPR028994 (15.3%) IPR022045 (14.6%) IPR006530 (14%)" "Integrin alpha, N-terminal (15.3%) Insecticide toxin TcdB middle/N-terminal (14.6%) YD repeat (14%)" LGGQAMDAMAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005886 (18.9%) GO:0033177 (18.9%) GO:0045259 (18.9%)" "GO:0008289 (18.9%) GO:0046933 (18.9%) GO:0016787 (5.5%)" "plasma membrane (18.9%) proton-transporting two-sector ATPase complex, proton-transporting domain (18.9%) proton-transporting ATP synthase complex (18.9%)" "lipid binding (18.9%) proton-transporting ATP synthase activity, rotational mechanism (18.9%) hydrolase activity (5.5%)" "IPR000454 (16.7%) IPR002379 (16.7%) IPR005953 (16.7%)" "ATP synthase, F0 complex, subunit C (16.7%) V-ATPase proteolipid subunit C-like domain (16.7%) ATP synthase, F0 complex, subunit C, bacterial/chloroplast (16.7%)" LSYGQVGGFDLGGKPSGYYTTAESLVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.14.- (100%) Dipeptidyl-peptidases and tripeptidyl-peptidases (100%) "GO:0043171 (25.2%) GO:0006508 (24.5%)" "GO:0008239 (25.2%) GO:0070009 (25.2%)" "peptide catabolic process (25.2%) proteolysis (24.5%)" "dipeptidyl-peptidase activity (25.2%) serine-type aminopeptidase activity (25.2%)" "IPR019500 (34.6%) IPR009003 (32.7%) IPR043504 (32.7%)" "Peptidase S46 (34.6%) Peptidase S1, PA clan (32.7%) Peptidase S1, PA clan, chymotrypsin-like fold (32.7%)" GFTTVLCPDGEVGYKEFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (20%) IPR001867 (20%) IPR011006 (20%)" "Signal transduction response regulator, receiver domain (20%) OmpR/PhoB-type DNA-binding domain (20%) CheY-like superfamily (20%)" GNDHLFELMEDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.190 (75%) 2.1.1.- (12.5%) 2.1.1.189 (12.5%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (75%) Methyltransferases (12.5%) 23S rRNA (uracil(747)-C(5))-methyltransferase (12.5%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR002792 (16.7%) IPR010280 (16.7%) IPR012340 (16.7%)" "TRAM domain (16.7%) (Uracil-5)-methyltransferase family (16.7%) Nucleic acid-binding, OB-fold (16.7%)" YGLDLLWVGAR Pseudomonadati Bacteria Pseudomonadati 5.4.99.5 (100%) chorismate mutase (100%) GO:0046417 (48.6%) "GO:0004106 (48.6%) GO:0003849 (2.7%)" chorismate metabolic process (48.6%) "chorismate mutase activity (48.6%) 3-deoxy-7-phosphoheptulonate synthase activity (2.7%)" "IPR006218 (18.6%) IPR052899 (18.6%) IPR002701 (17.6%)" "DAHP synthetase I/KDSA (18.6%) Class-I DAHP synthase (18.6%) Chorismate mutase II, prokaryotic-type (17.6%)" ETFSFTTSEGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (80%) 3.4.14.12 (20%)" "Acting on peptide bonds (peptidases) (80%) Xaa-Xaa-Pro tripeptidyl-peptidase (20%)" GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" YVNNANEELDGVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) VLLVEDVPLELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0000160 (49.3%) "GO:0003677 (49.3%) GO:0016301 (1.3%)" phosphorelay signal transduction system (49.3%) "DNA binding (49.3%) kinase activity (1.3%)" "IPR001789 (25.1%) IPR039420 (25.1%) IPR045976 (25.1%)" "Signal transduction response regulator, receiver domain (25.1%) Transcriptional regulatory protein WalR-like (25.1%) Domain of unknown function DUF5932 (25.1%)" LLVPVKDGENLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001911 (48.7%) IPR038380 (48.7%) IPR018278 (2.5%)" "Small ribosomal subunit protein bS21 (48.7%) Small ribosomal subunit protein bS21 superfamily (48.7%) Small ribosomal subunit protein bS21, conserved site (2.5%)" LGSLATFDSSDNMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024361 (21.7%) IPR052595 (21.7%) IPR013783 (20.9%)" "Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.7%) Leucine-rich repeat-containing protein 69/Receptor-like (21.7%) Immunoglobulin-like fold (20.9%)" FDLMGVHDLETMQALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (51.2%) "GO:0016798 (33.8%) GO:0051060 (15%)" carbohydrate metabolic process (51.2%) "hydrolase activity, acting on glycosyl bonds (33.8%) pullulanase activity (15%)" "IPR006047 (15%) IPR011840 (14.6%) IPR049117 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (15%) Pullulanase, type I (14.6%) Pullulanase, all-beta domain (14.6%)" MKDLNCFTVESAMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000911 (14.3%) IPR006519 (14.3%) IPR020783 (14.3%)" "Ribosomal protein uL11 (14.3%) Large ribosomal subunit protein uL11, bacteria (14.3%) Large ribosomal subunit protein uL11, C-terminal (14.3%)" LSASFDVK Pseudomonadati Bacteria Pseudomonadati GO:0006826 (10%) GO:0009279 (90%) iron ion transport (10%) cell outer membrane (90%) "IPR008969 (13.5%) IPR012910 (13.5%) IPR023996 (13.5%)" "Carboxypeptidase-like, regulatory domain superfamily (13.5%) TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%)" VSLGFEDNNGLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" VLGGDAVGMSTVPEVLVAR root "2.4.2.1 (94.5%) 3.5.4.5 (3.6%) 3.2.2.9 (1.8%)" "purine-nucleoside phosphorylase (94.5%) cytidine deaminase (3.6%) adenosylhomocysteine nucleosidase (1.8%)" "GO:0009116 (24.9%) GO:0006206 (1.2%) GO:0006213 (1.2%)" "GO:0005737 (26.6%) GO:0005886 (1.2%)" "GO:0004731 (26.6%) GO:0004126 (1.2%) GO:0004139 (1.2%)" "nucleoside metabolic process (24.9%) pyrimidine nucleobase metabolic process (1.2%) pyrimidine nucleoside metabolic process (1.2%)" "cytoplasm (26.6%) plasma membrane (1.2%)" "purine-nucleoside phosphorylase activity (26.6%) cytidine deaminase activity (1.2%) deoxyribose-phosphate aldolase activity (1.2%)" "IPR000845 (16.5%) IPR011268 (16.5%) IPR035994 (16.1%)" "Nucleoside phosphorylase domain (16.5%) Purine nucleoside phosphorylase (16.5%) Nucleoside phosphorylase superfamily (16.1%)" FFEPLRDVVASLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" ADAETLPATDRDGLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR039448 (35%) IPR011050 (32.5%) IPR012334 (32.5%)" "Right handed beta helix domain (35%) Pectin lyase fold/virulence factor (32.5%) Pectin lyase fold (32.5%)" EAHYLLGVAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) LVFHGQTSLFDALNQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (30.3%) GO:0008610 (4.5%)" GO:0016020 (30.3%) GO:0008780 (34.8%) "lipid A biosynthetic process (30.3%) lipid biosynthetic process (4.5%)" membrane (30.3%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.8%) "IPR010137 (20.4%) IPR029098 (20.4%) IPR001451 (19.7%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.4%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.4%) Hexapeptide repeat (19.7%)" DLDWSNLSFGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (12.6%) GO:0009098 (12.6%) GO:0009099 (12.6%)" "GO:0004084 (17.1%) GO:0052654 (7.2%) GO:0052655 (7.2%)" "isoleucine biosynthetic process (12.6%) L-leucine biosynthetic process (12.6%) L-valine biosynthetic process (12.6%)" "branched-chain-amino-acid transaminase activity (17.1%) L-leucine-2-oxoglutarate transaminase activity (7.2%) L-valine-2-oxoglutarate transaminase activity (7.2%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" ATLNYYMENAHFMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (32.2%) "GO:0030170 (33.9%) GO:0010285 (32.2%) GO:0008483 (1.7%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (32.2%) "pyridoxal phosphate binding (33.9%) L,L-diaminopimelate aminotransferase activity (32.2%) transaminase activity (1.7%)" "IPR004839 (21.5%) IPR019942 (21.5%) IPR015422 (19.4%)" "Aminotransferase, class I/classII, large domain (21.5%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21.5%) Pyridoxal phosphate-dependent transferase, small domain (19.4%)" DAHVYECDNYEEFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR004499 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Proline-tRNA ligase, class IIa, archaeal-type (11.3%)" EVQVVALNDLCPVDYMAYMLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (19.4%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (19.4%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" LQQPKDEDGVELEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0051301 (10%) GO:0051603 (10%)" GO:0009376 (10%) "GO:0005524 (10%) GO:0008233 (10%) GO:0008270 (10%)" "cell division (10%) proteolysis involved in protein catabolic process (10%)" HslUV protease complex (10%) "ATP binding (10%) peptidase activity (10%) zinc ion binding (10%)" "IPR003593 (11.3%) IPR003959 (11.3%) IPR004487 (11.3%)" "AAA+ ATPase domain (11.3%) ATPase, AAA-type, core (11.3%) Clp protease, ATP-binding subunit ClpX (11.3%)" TLVTTEVLAELAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.4.2.- (50%) 5.4.2.2 (50%)" "Phosphotransferases (phosphomutases) (50%) phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (50%)" "GO:0005975 (25%) GO:0006166 (25%)" "GO:0008973 (25%) GO:0000287 (24.5%) GO:0004614 (0.5%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "phosphopentomutase activity (25%) magnesium ion binding (24.5%) phosphoglucomutase activity (0.5%)" "IPR005846 (13.8%) IPR005844 (13.6%) IPR005845 (13.6%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (13.8%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (13.6%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (13.6%)" KLFVVGTK root "2.7.1.159 (33.3%) 3.1.3.- (33.3%) 2.7.1.134 (16.7%)" "inositol-1,3,4-trisphosphate 5/6-kinase (33.3%) Phosphoric monoester hydrolases (33.3%) inositol-tetrakisphosphate 1-kinase (16.7%)" "GO:0005975 (27.5%) GO:0032957 (1.9%)" GO:0005737 (3.1%) "GO:0004553 (27.5%) GO:0030246 (27.5%) GO:0000287 (1.9%)" "carbohydrate metabolic process (27.5%) inositol trisphosphate metabolic process (1.9%)" cytoplasm (3.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (27.5%) carbohydrate binding (27.5%) magnesium ion binding (1.9%)" "IPR041542 (12.5%) IPR005084 (12.2%) IPR006584 (12.2%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (12.5%) Carbohydrate binding module family 6 (12.2%) Cellulose binding, type IV (12.2%)" ENELLALLCAHSNELLQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006355 (20.2%) GO:0000160 (0.6%)" "GO:0005829 (19.6%) GO:0032993 (19.6%)" "GO:0000156 (19.6%) GO:0000976 (19.6%) GO:0003677 (0.6%)" "regulation of DNA-templated transcription (20.2%) phosphorelay signal transduction system (0.6%)" "cytosol (19.6%) protein-DNA complex (19.6%)" "phosphorelay response regulator activity (19.6%) transcription cis-regulatory region binding (19.6%) DNA binding (0.6%)" "IPR001867 (17.6%) IPR001789 (17%) IPR036388 (17%)" "OmpR/PhoB-type DNA-binding domain (17.6%) Signal transduction response regulator, receiver domain (17%) Winged helix-like DNA-binding domain superfamily (17%)" EEMKEVDVQVLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR006665 (33.9%) IPR050330 (33.9%) IPR036737 (32.2%)" "OmpA-like domain (33.9%) Bacterial Outer Membrane Structural/Functional (33.9%) OmpA-like domain superfamily (32.2%)" LEELSGLSAEEAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.8%) "GO:0005886 (19.3%) GO:0016020 (0.5%)" "GO:0003723 (20.4%) GO:0016787 (20.1%) GO:0004521 (19.3%)" mRNA catabolic process (19.8%) "plasma membrane (19.3%) membrane (0.5%)" "RNA binding (20.4%) hydrolase activity (20.1%) RNA endonuclease activity (19.3%)" "IPR004087 (12.6%) IPR004088 (12.6%) IPR022711 (12.6%)" "K Homology domain (12.6%) K Homology domain, type 1 (12.6%) Ribonuclease Y, N-terminal (12.6%)" NLEGLDAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50%) "GO:0016798 (34.7%) GO:0051060 (15.3%)" carbohydrate metabolic process (50%) "hydrolase activity, acting on glycosyl bonds (34.7%) pullulanase activity (15.3%)" "IPR006047 (14.8%) IPR011840 (14.8%) IPR049117 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Pullulanase, type I (14.8%) Pullulanase, all-beta domain (14.8%)" TTGLLSEYTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.3%) IPR006102 (7.3%) IPR006103 (7.3%)" "Beta galactosidase small chain/ domain 5 (7.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.3%) Glycoside hydrolase family 2, catalytic domain (7.3%)" AGFTAVQTSPVHER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35%) "GO:0004556 (32.5%) GO:0043169 (32.5%)" carbohydrate metabolic process (35%) "alpha-amylase activity (32.5%) cation binding (32.5%)" "IPR006047 (17.5%) IPR031965 (17.5%) IPR006046 (16.3%)" "Glycosyl hydrolase family 13, catalytic domain (17.5%) Starch-binding module 26 (17.5%) Alpha amylase (16.3%)" LMDKLTELWATGDTQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.1%) GO:0005829 (32.1%) "GO:0008926 (32.1%) GO:0009026 (3.8%)" mannitol catabolic process (32.1%) cytosol (32.1%) "mannitol-1-phosphate 5-dehydrogenase activity (32.1%) tagaturonate reductase activity (3.8%)" "IPR013118 (21.5%) IPR013131 (21.5%) IPR008927 (19%)" "Mannitol dehydrogenase, C-terminal (21.5%) Mannitol dehydrogenase, N-terminal (21.5%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (19%)" LDNEGVGSVNLGMFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) LQEDYHTAEQNYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.4.1.13 (97.5%) 1.4.-.- (2.5%)" "glutamate synthase (NADPH) (97.5%) Acting on the CH-NH2 group of donors (2.5%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.2%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.2%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" KGAALNAVQLAEYLLK Bacteria Bacteria 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0019877 (11.1%) GO:0009088 (11%) GO:0009089 (11%)" "GO:0046983 (11.2%) GO:0004073 (11.1%) GO:0050661 (11.1%)" "diaminopimelate biosynthetic process (11.1%) threonine biosynthetic process (11%) lysine biosynthetic process via diaminopimelate (11%)" "protein dimerization activity (11.2%) aspartate-semialdehyde dehydrogenase activity (11.1%) NADP binding (11.1%)" "IPR012280 (19.1%) IPR000534 (18.8%) IPR005986 (18.8%)" "Semialdehyde dehydrogenase, dimerisation domain (19.1%) Semialdehyde dehydrogenase, NAD-binding (18.8%) Aspartate-semialdehyde dehydrogenase, beta-type (18.8%)" QYYPDLTNNYFTSGLALVHSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (13.6%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (13.6%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" MYYMAQNTSEQLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" NTYNALVAASK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (35%) IPR050678 (35%) IPR027417 (30%)" "AAA domain (35%) DNA Partitioning ATPase (35%) P-loop containing nucleoside triphosphate hydrolase (30%)" TSSLQYENDDVMR root 2.3.1.54 (100%) formate C-acetyltransferase (100%) "GO:0006006 (32.5%) GO:0005975 (0.4%)" GO:0005829 (33.4%) "GO:0008861 (33.4%) GO:0016829 (0.4%)" "glucose metabolic process (32.5%) carbohydrate metabolic process (0.4%)" cytosol (33.4%) "formate C-acetyltransferase activity (33.4%) lyase activity (0.4%)" "IPR004184 (20.2%) IPR050244 (20.2%) IPR001150 (20%)" "Pyruvate formate lyase domain (20.2%) Autonomous Glycyl Radical Cofactor (20.2%) Glycine radical domain (20%)" YSLLFSK root "1.14.11.33 (16.7%) 7.1.1.2 (14.3%) 2.7.7.6 (7.1%)" "DNA oxidative demethylase (16.7%) NADH:ubiquinone reductase (H(+)-translocating) (14.3%) DNA-directed RNA polymerase (7.1%)" "GO:0050821 (2%) GO:0003333 (1.1%) GO:0006307 (1.1%)" "GO:0016020 (9.9%) GO:0005886 (5.9%) GO:0005829 (3.1%)" "GO:0046872 (4.7%) GO:0008270 (3.3%) GO:0016491 (3.1%)" "protein stabilization (2%) amino acid transmembrane transport (1.1%) DNA alkylation repair (1.1%)" "membrane (9.9%) plasma membrane (5.9%) cytosol (3.1%)" "metal ion binding (4.7%) zinc ion binding (3.3%) oxidoreductase activity (3.1%)" "IPR005123 (3.4%) IPR027443 (2.9%) IPR044861 (2.7%)" "Oxoglutarate/iron-dependent dioxygenase domain (3.4%) Isopenicillin N synthase-like superfamily (2.9%) Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain (2.7%)" QLVANAGGEGSVVVNK Pseudomonadati Bacteria Pseudomonadati 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.1%) GO:0005737 (16.3%) "GO:0005524 (17.1%) GO:0140662 (17.1%) GO:0016853 (16.3%)" protein refolding (17.1%) cytoplasm (16.3%) "ATP binding (17.1%) ATP-dependent protein folding chaperone (17.1%) isomerase activity (16.3%)" "IPR001844 (17.2%) IPR002423 (17.2%) IPR027413 (16.8%)" "Chaperonin Cpn60/GroEL (17.2%) Chaperonin Cpn60/GroEL/TCP-1 family (17.2%) GroEL-like equatorial domain superfamily (16.8%)" EAYNMFCCSGLLFNHESER root 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (33.6%) "GO:0008446 (33.6%) GO:0070401 (32.2%) GO:0016829 (0.7%)" 'de novo' GDP-L-fucose biosynthetic process (33.6%) "GDP-mannose 4,6-dehydratase activity (33.6%) NADP+ binding (32.2%) lyase activity (0.7%)" "IPR006368 (33.4%) IPR016040 (33.4%) IPR036291 (33.1%)" "GDP-mannose 4,6-dehydratase (33.4%) NAD(P)-binding domain (33.4%) NAD(P)-binding domain superfamily (33.1%)" SAFNFLHACSPLMLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (30.6%) GO:0030497 (2.8%)" "GO:0004316 (30.6%) GO:0051287 (30.6%) GO:0016616 (2.8%)" "fatty acid biosynthetic process (30.6%) fatty acid elongation (2.8%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (30.6%) NAD binding (30.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (2.8%)" "IPR002347 (18.3%) IPR036291 (18.3%) IPR020904 (16.9%)" "Short-chain dehydrogenase/reductase SDR (18.3%) NAD(P)-binding domain superfamily (18.3%) Short-chain dehydrogenase/reductase, conserved site (16.9%)" EGNDLLRDMLESGVLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (22.5%) GO:0045259 (22.5%)" "GO:0005524 (22.5%) GO:0046933 (22.5%) GO:0016787 (9.9%)" "plasma membrane (22.5%) proton-transporting ATP synthase complex (22.5%)" "ATP binding (22.5%) proton-transporting ATP synthase activity, rotational mechanism (22.5%) hydrolase activity (9.9%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" VFLYYASSDTR Bacteria Bacteria 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (27.1%) GO:0071555 (27.1%)" "GO:0016758 (27.1%) GO:0016798 (16.7%) GO:0016757 (1.1%)" "carbohydrate metabolic process (27.1%) cell wall organization (27.1%)" "hexosyltransferase activity (27.1%) hydrolase activity, acting on glycosyl bonds (16.7%) glycosyltransferase activity (1.1%)" "IPR007184 (33.5%) IPR023296 (33.2%) IPR028583 (32.9%)" "Mannoside phosphorylase (33.5%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (33.2%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (32.9%)" EGMSLVVFPEGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.51 (100%) 1-acylglycerol-3-phosphate O-acyltransferase (100%) GO:0006654 (34.8%) GO:0016020 (30.5%) GO:0003841 (34.8%) phosphatidic acid biosynthetic process (34.8%) membrane (30.5%) 1-acylglycerol-3-phosphate O-acyltransferase activity (34.8%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) SVFTDPQLQSLLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" NLVDQNVSDYWLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (14.7%) IPR039426 (14.7%) IPR012910 (14.3%)" "TonB-dependent receptor-like, beta-barrel (14.7%) TonB-dependent receptor-like (14.7%) TonB-dependent receptor, plug domain (14.3%)" AYAMTGWR root "2.6.1.- (94.7%) 2.6.1.1 (5%) 2.6.1.79 (0.1%)" "Transaminases (94.7%) aspartate transaminase (5%) glutamate--prephenate aminotransferase (0.1%)" "GO:0006520 (32.7%) GO:0009095 (0.1%) GO:0035556 (0%)" "GO:0005737 (0.4%) GO:0016020 (0%)" "GO:0030170 (32.8%) GO:0008483 (22.4%) GO:0004069 (10.4%)" "amino acid metabolic process (32.7%) aromatic amino acid family biosynthetic process, prephenate pathway (0.1%) intracellular signal transduction (0%)" "cytoplasm (0.4%) membrane (0%)" "pyridoxal phosphate binding (32.8%) transaminase activity (22.4%) L-aspartate:2-oxoglutarate aminotransferase activity (10.4%)" "IPR004839 (16.7%) IPR050596 (16.7%) IPR015421 (16.7%)" "Aminotransferase, class I/classII, large domain (16.7%) Aspartate/prephenate aminotransferase-like (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" LSGVTTEYGYGNSSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VSGFVSLMR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.8.4.3 (100%) tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase (100%) GO:0005829 (24.8%) "GO:0035597 (24.8%) GO:0046872 (24.8%) GO:0051539 (24.8%)" cytosol (24.8%) "tRNA-2-methylthio-N(6)-dimethylallyladenosine(37) synthase activity (24.8%) metal ion binding (24.8%) 4 iron, 4 sulfur cluster binding (24.8%)" "IPR002792 (12.2%) IPR005839 (12.2%) IPR006463 (12.2%)" "TRAM domain (12.2%) Methylthiotransferase (12.2%) tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB (12.2%)" LKSYDHQLVDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0000049 (20%) GO:0003735 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "tRNA binding (20%) structural constituent of ribosome (20%)" "IPR001848 (25%) IPR018268 (25%) IPR027486 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10, conserved site (25%) Small ribosomal subunit protein uS10 domain (25%)" AVEGAATQSVGNQDELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0006002 (14.5%) GO:0009749 (14.5%)" GO:0005829 (14.5%) "GO:0003872 (14.5%) GO:0046872 (14.5%) GO:0005524 (13.7%)" "fructose 6-phosphate metabolic process (14.5%) response to glucose (14.5%)" cytosol (14.5%) "6-phosphofructokinase activity (14.5%) metal ion binding (14.5%) ATP binding (13.7%)" "IPR000023 (25.4%) IPR022953 (25.4%) IPR035966 (25.4%)" "Phosphofructokinase domain (25.4%) ATP-dependent 6-phosphofructokinase (25.4%) Phosphofructokinase superfamily (25.4%)" NLTTVGLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016740 (100%) transferase activity (100%) "IPR032533 (33.6%) IPR049208 (33.6%) IPR011004 (32.8%)" "Domain of unknown function DUF4954 (33.6%) Domain of unknown function DUF6819 (33.6%) Trimeric LpxA-like superfamily (32.8%)" ASAVFLHETTLATFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" NYAELVNDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (55.6%) IPR009057 (44.4%)" "AraC-like, DNA binding HTH domain (55.6%) Homedomain-like superfamily (44.4%)" KGLGLAYDVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (22.9%) GO:0009636 (18.1%) GO:0043418 (18.1%)" GO:0005737 (18.1%) GO:0070005 (22.9%) "proteolysis (22.9%) response to toxic substance (18.1%) homocysteine catabolic process (18.1%)" cytoplasm (18.1%) cysteine-type aminopeptidase activity (22.9%) "IPR004134 (32.2%) IPR000169 (30.5%) IPR038765 (30.5%)" "Peptidase C1B, bleomycin hydrolase (32.2%) Cysteine peptidase, cysteine active site (30.5%) Papain-like cysteine peptidase superfamily (30.5%)" SMEMLNAAEYLAAAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023997 (14.7%) IPR039426 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%) TonB-dependent receptor-like (14.7%)" NLYDLPNLLLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.3%) IPR041542 (20.3%) IPR051795 (20.3%)" "Glycoside hydrolase, family 43 (20.3%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.3%) Glycosyl Hydrolase Family 43 (20.3%)" YLGVGNESWGCGGNMRPEYYSDLFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (27%) IPR013780 (25.4%) IPR017853 (25.4%)" "Alpha-L-arabinofuranosidase, C-terminal (27%) Glycosyl hydrolase, all-beta (25.4%) Glycoside hydrolase superfamily (25.4%)" AQNDMTNQLLELPNLPCEQVPEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.11 (100%) serine--tRNA ligase (100%) "GO:0006434 (23.8%) GO:0006412 (1.6%)" GO:0005737 (23.8%) "GO:0004828 (23.8%) GO:0005524 (23.8%) GO:0000166 (1.6%)" "seryl-tRNA aminoacylation (23.8%) translation (1.6%)" cytoplasm (23.8%) "serine-tRNA ligase activity (23.8%) ATP binding (23.8%) nucleotide binding (1.6%)" "IPR010978 (14.7%) IPR015866 (14.7%) IPR042103 (14.7%)" "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm (14.7%) Serine-tRNA synthetase, type1, N-terminal (14.7%) Serine-tRNA synthetase, type1, N-terminal domain superfamily (14.7%)" LSTPNLLNTYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.6%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.6%)" "IPR000241 (17.2%) IPR002052 (17.2%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.2%) DNA methylase, N-6 adenine-specific, conserved site (17.2%) THUMP domain (16.8%)" AASNLAQMNLDDTREK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.3%) "GO:0009279 (20.3%) GO:1990281 (20.3%)" "GO:0015288 (20.3%) GO:0015562 (20.3%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.3%) efflux pump complex (20.3%)" "porin activity (20.3%) efflux transmembrane transporter activity (20.3%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LNYYLSMGYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13%) IPR023996 (13%) IPR023997 (13%)" "TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13%)" KGDSPANYYWEVTDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.6%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.6%) "IPR003284 (18.3%) IPR028994 (16%) IPR006530 (13%)" "Salmonella virulence plasmid 65kDa B protein (18.3%) Integrin alpha, N-terminal (16%) YD repeat (13%)" LAEVFATQQLQGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006605 (19.8%) GO:0043952 (19.8%) GO:0065002 (19.8%)" GO:0005886 (20.3%) GO:0015450 (19.8%) "protein targeting (19.8%) protein transport by the Sec complex (19.8%) intracellular protein transmembrane transport (19.8%)" plasma membrane (20.3%) protein-transporting ATPase activity (19.8%) "IPR022813 (11.4%) IPR048631 (11.4%) IPR005665 (11.1%)" "Protein-export membrane protein SecD/SecF, archaeal and bacterial (11.4%) Protein translocase subunit SecDF, P1 domain, N-terminal (11.4%) Protein-export membrane protein SecF, bacterial (11.1%)" TADGYVPGVNDLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019646 (14.3%) "GO:0005886 (14.3%) GO:0070069 (14.3%)" "GO:0009055 (14.3%) GO:0016682 (14.3%) GO:0020037 (14.3%)" aerobic electron transport chain (14.3%) "plasma membrane (14.3%) cytochrome complex (14.3%)" "electron transfer activity (14.3%) oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor (14.3%) heme binding (14.3%)" IPR002585 (100%) Cytochrome ubiquinol oxidase subunit 1 (100%) LLTHDDQLNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025324 (100%) Protein of unknown function DUF4230 (100%) LDEALFTTELSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (92.5%) GO:0015344 (7.5%) cell outer membrane (92.5%) siderophore uptake transmembrane transporter activity (7.5%) "IPR036942 (92.5%) IPR039426 (7.5%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (92.5%) TonB-dependent receptor-like (7.5%)" YVDDATGNPLYQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LEQATLDMLGSADK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.4%) GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0140662 (17.4%) GO:0016853 (15.9%)" protein refolding (17.4%) cytoplasm (15.9%) "ATP binding (17.4%) ATP-dependent protein folding chaperone (17.4%) isomerase activity (15.9%)" "IPR001844 (17.1%) IPR002423 (17.1%) IPR027409 (17.1%)" "Chaperonin Cpn60/GroEL (17.1%) Chaperonin Cpn60/GroEL/TCP-1 family (17.1%) GroEL-like apical domain superfamily (17.1%)" TAEDALNTLR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34%) IPR033985 (34%) IPR011990 (32.1%)" "RagB/SusD domain (34%) SusD-like, N-terminal (34%) Tetratricopeptide-like helical domain superfamily (32.1%)" DQGSYATWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR032317 (50%) IPR011053 (48.4%) IPR039562 (1.6%)" "Unknown (50%) Single hybrid motif (48.4%) Unknown (1.6%)" VVTAVLPMEPAAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.3%) IPR003156 (9.3%) IPR012947 (9.3%)" "Alanine-tRNA ligase, class IIc (9.3%) DHHA1 domain (9.3%) Threonyl/alanyl tRNA synthetase, SAD (9.3%)" EAEAYPGPSLLLAYAPCLNHGLKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.8%) GO:0022900 (14.1%) GO:0044281 (13.7%)" "GO:0030976 (14.4%) GO:0005506 (14.1%) GO:0051539 (14.1%)" "response to oxidative stress (14.8%) electron transport chain (14.1%) small molecule metabolic process (13.7%)" "thiamine pyrophosphate binding (14.4%) iron ion binding (14.1%) 4 iron, 4 sulfur cluster binding (14.1%)" "IPR050722 (8.1%) IPR011766 (7.9%) IPR029061 (7.9%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Thiamin diphosphate-binding fold (7.9%)" FDQWASDPNLLATSQQDALDHPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" DWEDLMPVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.2%) IPR010918 (11.2%) IPR040707 (11.2%)" "Phosphoribosylformylglycinamidine synthase PurL (11.2%) PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.2%)" VQLQNAGDFDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" SLEVSDQHLETLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LETSVLDCLGCGNCADVCPGKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" LHAGQLVSGEWFVDSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.2.9 (100%) adenosylhomocysteine nucleosidase (100%) "GO:0009164 (16.7%) GO:0019284 (16.7%) GO:0019509 (16.7%)" GO:0005829 (16.7%) "GO:0008782 (16.7%) GO:0008930 (16.7%)" "nucleoside catabolic process (16.7%) L-methionine salvage from S-adenosylmethionine (16.7%) L-methionine salvage from methylthioadenosine (16.7%)" cytosol (16.7%) "adenosylhomocysteine nucleosidase activity (16.7%) methylthioadenosine nucleosidase activity (16.7%)" "IPR000845 (34.4%) IPR010049 (34.4%) IPR035994 (31.3%)" "Nucleoside phosphorylase domain (34.4%) MTA/SAH nucleosidase (34.4%) Nucleoside phosphorylase superfamily (31.3%)" YYEGFAVNCLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.9%) "GO:0005886 (16.2%) GO:0016020 (0.7%)" "GO:0016655 (16.9%) GO:0051537 (16.9%) GO:0009055 (16.2%)" sodium ion transport (16.9%) "plasma membrane (16.2%) membrane (0.7%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.9%) 2 iron, 2 sulfur cluster binding (16.9%) electron transfer activity (16.2%)" "IPR001433 (10.1%) IPR008333 (10.1%) IPR010205 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%) Na(+)-translocating NADH-quinone reductase subunit F (10.1%)" AWGWNVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.2.1.1 (100%) transketolase (100%) GO:0006098 (25.2%) GO:0005829 (25.2%) "GO:0004802 (25.2%) GO:0046872 (24.5%)" pentose-phosphate shunt (25.2%) cytosol (25.2%) "transketolase activity (25.2%) metal ion binding (24.5%)" "IPR005474 (12.9%) IPR029061 (12.9%) IPR033247 (12.9%)" "Transketolase, N-terminal (12.9%) Thiamin diphosphate-binding fold (12.9%) Transketolase family (12.9%)" VWGMESFGFSAPYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.2.1.1 (96.8%) 2.2.1.- (3.2%)" "transketolase (96.8%) Transketolases and transaldolases (3.2%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005475 (12.6%) IPR009014 (12.6%) IPR020826 (12.6%)" "Transketolase-like, pyrimidine-binding domain (12.6%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.6%) Transketolase binding site (12.6%)" NEDGSGVLVGLTNLGNVVGYER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (15.3%) GO:0046912 (9.7%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (15.3%) acyltransferase activity, acyl groups converted into alkyl on transfer (9.7%)" "IPR002020 (20.9%) IPR016142 (19.8%) IPR016143 (19.8%)" "Citrate synthase (20.9%) Citrate synthase-like, large alpha subdomain (19.8%) Citrate synthase-like, small alpha subdomain (19.8%)" WTQAYSVSGGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" SREQFQLSDFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0000049 (20%) GO:0003735 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "tRNA binding (20%) structural constituent of ribosome (20%)" "IPR001848 (25%) IPR018268 (25%) IPR027486 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10, conserved site (25%) Small ribosomal subunit protein uS10 domain (25%)" VLANNVVELTRPSSGETSYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007298 (100%) Copper resistance lipoprotein NlpE (100%) MLEQENFDVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) ELSMSDLVFK root "GO:0006281 (25%) GO:0006310 (25%)" "GO:0003676 (25%) GO:0008409 (25%)" "DNA repair (25%) DNA recombination (25%)" "nucleic acid binding (25%) 5'-3' exonuclease activity (25%)" "IPR001667 (16.5%) IPR003156 (16.5%) IPR004610 (16.5%)" "DDH domain (16.5%) DHHA1 domain (16.5%) Bacterial RecJ exonuclease (16.5%)" LGLQAFQPK root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) "GO:0000428 (16.8%) GO:0009507 (0.7%) GO:0009536 (0.1%)" "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (15.5%)" DNA-templated transcription (16.8%) "DNA-directed RNA polymerase complex (16.8%) chloroplast (0.7%) plastid (0.1%)" "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (15.5%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR045867 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) DNA-directed RNA polymerase, subunit beta-prime (9.3%)" VNFASVHNPYPYPDFLDVQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.8%) IPR007121 (7.8%) IPR007641 (7.8%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.8%) RNA polymerase, beta subunit, conserved site (7.8%) RNA polymerase Rpb2, domain 7 (7.8%)" YNLEYNGAYNGSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.8%) IPR023996 (14.8%) IPR023997 (14.8%)" "TonB-dependent receptor, plug domain (14.8%) TonB-dependent outer membrane protein, SusC/RagA (14.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.8%)" ENVMNTLGEYLSAQGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" KAPEVCPVCNHPQSYFQLEAQNY Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005506 (50%) GO:0016491 (45%) GO:0016692 (5%)" "iron ion binding (50%) oxidoreductase activity (45%) NADH peroxidase activity (5%)" "IPR003251 (14.7%) IPR009040 (14.7%) IPR024934 (14.7%)" "Rubrerythrin, diiron-binding domain (14.7%) Ferritin-like diiron domain (14.7%) Rubredoxin-like domain (14.7%)" TLEGASYLLQTYPDKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.185 (100%) non-reducing end beta-L-arabinofuranosidase (100%) GO:0005975 (59.1%) "GO:0016787 (37.6%) GO:0102478 (2.7%) GO:0016798 (0.7%)" carbohydrate metabolic process (59.1%) "hydrolase activity (37.6%) beta-L-arabinofuranosidase activity (2.7%) hydrolase activity, acting on glycosyl bonds (0.7%)" "IPR012878 (15%) IPR049174 (15%) IPR008928 (14.9%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (15%) Non-reducing end beta-L-arabinofuranosidase-like (15%) Six-hairpin glycosidase superfamily (14.9%)" SLEDPQVQFFFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (20%) GO:0009636 (20%) GO:0043418 (20%)" GO:0005737 (20%) GO:0070005 (20%) "proteolysis (20%) response to toxic substance (20%) homocysteine catabolic process (20%)" cytoplasm (20%) cysteine-type aminopeptidase activity (20%) "IPR000169 (33.9%) IPR004134 (33.9%) IPR038765 (32.1%)" "Cysteine peptidase, cysteine active site (33.9%) Peptidase C1B, bleomycin hydrolase (33.9%) Papain-like cysteine peptidase superfamily (32.1%)" EVSDGVLAPGYTPEALEVLKEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "2.1.2.3 (92.3%) 3.5.4.10 (7.7%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (92.3%) IMP cyclohydrolase (7.7%)" GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (26.9%) IPR016193 (25%) IPR024051 (25%)" "Bifunctional purine biosynthesis protein PurH-like (26.9%) Cytidine deaminase-like (25%) AICAR transformylase, duplicated domain superfamily (25%)" LELYNEYGNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EALGYGLLVWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (50%) GO:0008237 (50%) proteolysis (50%) metallopeptidase activity (50%) IPR008757 (100%) Peptidase M6-like, domain (100%) DMGHGVNLVR Bacteria Bacteria 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25.1%) IPR010190 (25.1%) IPR032094 (25.1%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.1%) Diaminopimelate dehydrogenase, Ddh (25.1%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25.1%)" LSTYLTK root "1.1.1.205 (38.2%) 2.7.13.3 (28.1%) 3.4.21.102 (3.5%)" "IMP dehydrogenase (38.2%) histidine kinase (28.1%) C-terminal processing peptidase (3.5%)" "GO:0006177 (2%) GO:0006183 (2%) GO:0006508 (0.9%)" "GO:0016020 (3.6%) GO:0005737 (3%) GO:0005886 (1.6%)" "GO:0005524 (10.3%) GO:0016887 (8.2%) GO:0051082 (8.1%)" "GMP biosynthetic process (2%) GTP biosynthetic process (2%) proteolysis (0.9%)" "membrane (3.6%) cytoplasm (3%) plasma membrane (1.6%)" "ATP binding (10.3%) ATP hydrolysis activity (8.2%) unfolded protein binding (8.1%)" "IPR036890 (7.2%) IPR001404 (6%) IPR020568 (6%)" "Histidine kinase/HSP90-like ATPase superfamily (7.2%) Heat shock protein Hsp90 family (6%) Ribosomal protein uS5 domain 2-type superfamily (6%)" MSQADLAQLTAQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" AAALFTTR root 4.2.1.20 (100%) tryptophan synthase (100%) "GO:0006355 (2.3%) GO:0006680 (2.3%) GO:0008299 (2.3%)" "GO:0009279 (34.5%) GO:0016020 (8%) GO:0030313 (4.6%)" "GO:0003677 (6.9%) GO:0030246 (4.6%) GO:0004348 (2.3%)" "regulation of DNA-templated transcription (2.3%) glucosylceramide catabolic process (2.3%) isoprenoid biosynthetic process (2.3%)" "cell outer membrane (34.5%) membrane (8%) cell envelope (4.6%)" "DNA binding (6.9%) carbohydrate binding (4.6%) glucosylceramidase activity (2.3%)" "IPR011990 (17.3%) IPR012944 (16.2%) IPR033985 (16.2%)" "Tetratricopeptide-like helical domain superfamily (17.3%) RagB/SusD domain (16.2%) SusD-like, N-terminal (16.2%)" YGAPPHAGLAFGLDR root "6.1.1.12 (85.1%) 6.1.1.23 (14.2%) 6.1.1.- (0.7%)" "aspartate--tRNA ligase (85.1%) aspartate--tRNA(Asn) ligase (14.2%) Ligases forming aminoacyl-tRNA and related compounds (0.7%)" "GO:0006422 (19.4%) GO:0000278 (0.1%) GO:0006418 (0.1%)" "GO:0005737 (19.3%) GO:0000922 (0.1%) GO:0000930 (0.1%)" "GO:0005524 (19.5%) GO:0004815 (19.4%) GO:0003676 (19.1%)" "aspartyl-tRNA aminoacylation (19.4%) mitotic cell cycle (0.1%) tRNA aminoacylation for protein translation (0.1%)" "cytoplasm (19.3%) spindle pole (0.1%) gamma-tubulin complex (0.1%)" "ATP binding (19.5%) aspartate-tRNA ligase activity (19.4%) nucleic acid binding (19.1%)" "IPR004364 (9.2%) IPR045864 (9.2%) IPR002312 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (9.2%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%)" LFEEETKAGLEGYEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (19%) GO:0005829 (19%) "GO:0004612 (19%) GO:0005524 (19%) GO:0046872 (19%)" gluconeogenesis (19%) cytosol (19%) "phosphoenolpyruvate carboxykinase (ATP) activity (19%) ATP binding (19%) metal ion binding (19%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" FLHTLENMGPSPEPNLTVLYSSR root 2.3.1.54 (100%) formate C-acetyltransferase (100%) "GO:0006006 (32.8%) GO:0005975 (0.3%)" "GO:0005829 (33.3%) GO:0016020 (0.3%)" GO:0008861 (33.3%) "glucose metabolic process (32.8%) carbohydrate metabolic process (0.3%)" "cytosol (33.3%) membrane (0.3%)" formate C-acetyltransferase activity (33.3%) "IPR001150 (20.1%) IPR004184 (20.1%) IPR050244 (20.1%)" "Glycine radical domain (20.1%) Pyruvate formate lyase domain (20.1%) Autonomous Glycyl Radical Cofactor (20.1%)" SFGGLGLFALNEMGR Bacteria Bacteria GO:0006004 (33.3%) GO:0005737 (33.3%) GO:0008736 (33.3%) fucose metabolic process (33.3%) cytoplasm (33.3%) L-fucose isomerase activity (33.3%) "IPR015888 (51.2%) IPR009015 (48.8%)" "L-fucose isomerase, C-terminal (51.2%) L-fucose isomerase, N-terminal/central domain superfamily (48.8%)" LALGCTVVNFLNQTGAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (95%) GO:0015344 (5%) cell outer membrane (95%) siderophore uptake transmembrane transporter activity (5%) "IPR036942 (95%) IPR039426 (5%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (95%) TonB-dependent receptor-like (5%)" AGVDFTPR root GO:0010468 (5.6%) "GO:0009279 (61.1%) GO:0005634 (5.6%)" "GO:0003677 (5.6%) GO:0003955 (5.6%) GO:0008270 (5.6%)" regulation of gene expression (5.6%) "cell outer membrane (61.1%) nucleus (5.6%)" "DNA binding (5.6%) NAD(P)H dehydrogenase (quinone) activity (5.6%) zinc ion binding (5.6%)" "IPR008969 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "Carboxypeptidase-like, regulatory domain superfamily (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" DRDYDYAETLVNQFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.11 (100%) N-succinylornithine carbamoyltransferase (100%) "GO:0019240 (25%) GO:0042450 (25%)" "GO:0004585 (25%) GO:0016597 (25%)" "citrulline biosynthetic process (25%) L-arginine biosynthetic process via ornithine (25%)" "ornithine carbamoyltransferase activity (25%) amino acid binding (25%)" "IPR006130 (20%) IPR006131 (20%) IPR006132 (20%)" "Aspartate/ornithine carbamoyltransferase (20%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20%)" LTHQFQGVLTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.4 (100%) glutamate dehydrogenase (NADP(+)) (100%) GO:0006537 (25.5%) GO:0005829 (25.5%) "GO:0004354 (25.5%) GO:0000166 (23.6%)" glutamate biosynthetic process (25.5%) cytosol (25.5%) "glutamate dehydrogenase (NADP+) activity (25.5%) nucleotide binding (23.6%)" "IPR006095 (11.2%) IPR006096 (11.2%) IPR006097 (11.2%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.2%)" ATALKDGDEVVGNLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006281 (12.5%) GO:0006310 (12.5%) GO:0009432 (12.5%)" GO:0005829 (12.5%) "GO:0003684 (12.5%) GO:0003697 (12.5%) GO:0005524 (12.5%)" "DNA repair (12.5%) DNA recombination (12.5%) SOS response (12.5%)" cytosol (12.5%) "damaged DNA binding (12.5%) single-stranded DNA binding (12.5%) ATP binding (12.5%)" "IPR003593 (11.1%) IPR013765 (11.1%) IPR020584 (11.1%)" "AAA+ ATPase domain (11.1%) DNA recombination and repair protein RecA (11.1%) DNA recombination/repair protein RecA, conserved site (11.1%)" QVFGVTFEQGR root "2.1.2.3 (93.9%) 3.5.4.10 (5.1%) 1.1.1.205 (1%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (93.9%) IMP cyclohydrolase (5.1%) IMP dehydrogenase (1%)" "GO:0006189 (24.9%) GO:0006177 (0.2%)" GO:0005829 (24.9%) "GO:0003937 (24.9%) GO:0004643 (24.9%) GO:0003938 (0.2%)" "'de novo' IMP biosynthetic process (24.9%) GMP biosynthetic process (0.2%)" cytosol (24.9%) "IMP cyclohydrolase activity (24.9%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (24.9%) IMP dehydrogenase activity (0.2%)" "IPR002695 (25.1%) IPR016193 (24.9%) IPR024051 (24.9%)" "Bifunctional purine biosynthesis protein PurH-like (25.1%) Cytidine deaminase-like (24.9%) AICAR transformylase, duplicated domain superfamily (24.9%)" DYLLQQEGQYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0004519 (80%) GO:0004527 (20%)" "endonuclease activity (80%) exonuclease activity (20%)" "IPR005135 (51.6%) IPR036691 (48.4%)" "Endonuclease/exonuclease/phosphatase (51.6%) Endonuclease/exonuclease/phosphatase superfamily (48.4%)" VGDTLTHLARPCDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.5.0 (100%) Unknown (100%) GO:0045727 (16.8%) GO:0005886 (16.4%) "GO:0003924 (16.8%) GO:0005525 (16.8%) GO:0043022 (16.8%)" positive regulation of translation (16.8%) plasma membrane (16.4%) "GTPase activity (16.8%) GTP binding (16.8%) ribosome binding (16.8%)" "IPR000795 (10.1%) IPR004161 (10.1%) IPR006297 (10.1%)" "Translational (tr)-type GTP-binding domain (10.1%) Translation elongation factor EFTu-like, domain 2 (10.1%) Elongation factor 4 (10.1%)" EGWAPLKPTLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" AGVECEVSLENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044205 (16.7%) "GO:0009055 (16.7%) GO:0016491 (16.7%) GO:0046872 (16.7%)" 'de novo' UMP biosynthetic process (16.7%) "electron transfer activity (16.7%) oxidoreductase activity (16.7%) metal ion binding (16.7%)" "IPR019480 (11.2%) IPR037117 (11.2%) IPR039261 (11.2%)" "Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.2%) Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily (11.2%) Ferredoxin-NADP reductase (FNR), nucleotide-binding domain (11.2%)" NPFTLDSK root "1.2.7.1 (89.9%) 1.2.7.- (8.6%) 1.2.1.51 (1.1%)" "pyruvate synthase (89.9%) With an iron-sulfur protein as acceptor (8.6%) pyruvate dehydrogenase (NADP(+)) (1.1%)" "GO:0006979 (16.2%) GO:0022900 (15.2%) GO:0044281 (6.1%)" "GO:0005789 (0%) GO:0005829 (0%) GO:0014069 (0%)" "GO:0005506 (15.2%) GO:0051539 (15.2%) GO:0030976 (14.7%)" "response to oxidative stress (16.2%) electron transport chain (15.2%) small molecule metabolic process (6.1%)" "endoplasmic reticulum membrane (0%) cytosol (0%) postsynaptic density (0%)" "iron ion binding (15.2%) 4 iron, 4 sulfur cluster binding (15.2%) thiamine pyrophosphate binding (14.7%)" "IPR029061 (8.1%) IPR050722 (8.1%) IPR017896 (7.7%)" "Thiamin diphosphate-binding fold (8.1%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (7.7%)" VLYPPTLYPVCVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.3 (51.1%) 2.7.2.4 (48.9%)" "homoserine dehydrogenase (51.1%) aspartate kinase (48.9%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.1%) IPR001341 (7.1%) IPR001342 (7.1%)" "Aspartate/glutamate/uridylate kinase (7.1%) Aspartate kinase (7.1%) Homoserine dehydrogenase, catalytic (7.1%)" LQQDKQELENLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0034605 (19.7%) GO:0042026 (17.9%) GO:0006508 (1.7%)" GO:0005737 (19.7%) "GO:0005524 (19.7%) GO:0016887 (19.7%) GO:0008233 (1.7%)" "cellular response to heat (19.7%) protein refolding (17.9%) proteolysis (1.7%)" cytoplasm (19.7%) "ATP binding (19.7%) ATP hydrolysis activity (19.7%) peptidase activity (1.7%)" "IPR018368 (8.8%) IPR041546 (8.8%) IPR050130 (8.8%)" "ClpA/B, conserved site 1 (8.8%) ClpA/ClpB, AAA lid domain (8.8%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.8%)" EALTLLAQQGFHDVEFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (23.9%) "GO:0046872 (25.4%) GO:0051539 (25.4%) GO:0004333 (21.1%)" tricarboxylic acid cycle (23.9%) "metal ion binding (25.4%) 4 iron, 4 sulfur cluster binding (25.4%) fumarate hydratase activity (21.1%)" "IPR004646 (21.7%) IPR051208 (21.7%) IPR004647 (20.5%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (21.7%) Class-I Fumarase/Tartrate Dehydratase (21.7%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (20.5%)" VAMQDATAQMALLQFMNAGK Pseudomonadati Bacteria Pseudomonadati 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20%) "GO:0005829 (20%) GO:0005739 (0.1%)" "GO:0003994 (20%) GO:0051539 (20%) GO:0046872 (19.9%)" tricarboxylic acid cycle (20%) "cytosol (20%) mitochondrion (0.1%)" "aconitate hydratase activity (20%) 4 iron, 4 sulfur cluster binding (20%) metal ion binding (19.9%)" "IPR001030 (11.2%) IPR050926 (11.2%) IPR015931 (11.2%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.2%) Aconitase/IPM Isomerase (11.2%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (11.2%)" FYLYPLPEAEVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" VGNTLSENGTVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016740 (100%) transferase activity (100%) "IPR029044 (84.9%) IPR005835 (15.1%)" "Nucleotide-diphospho-sugar transferases (84.9%) Nucleotidyl transferase domain (15.1%)" GLVQRPLTFDDGSELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (20%) GO:0007165 (20%)" GO:0030288 (20%) "GO:0004175 (20%) GO:0008236 (20%)" "proteolysis (20%) signal transduction (20%)" outer membrane-bounded periplasmic space (20%) "endopeptidase activity (20%) serine-type peptidase activity (20%)" "IPR001478 (17%) IPR004447 (17%) IPR005151 (17%)" "PDZ domain (17%) C-terminal-processing peptidase S41A (17%) Tail specific protease (17%)" QADREGYPELAEAYK Bacteria Bacteria 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (23.9%) GO:0016491 (19%)" "iron ion binding (50%) peroxidase activity (23.9%) oxidoreductase activity (19%)" "IPR003251 (12.6%) IPR009040 (12.6%) IPR009078 (12.6%)" "Rubrerythrin, diiron-binding domain (12.6%) Ferritin-like diiron domain (12.6%) Ferritin-like superfamily (12.6%)" KWNPAMAPYLFMER Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (33.3%) "GO:0022627 (33.3%) GO:0005840 (0.2%)" GO:0003735 (33.3%) translation (33.3%) "cytosolic small ribosomal subunit (33.3%) ribosome (0.2%)" structural constituent of ribosome (33.3%) "IPR001865 (25.2%) IPR005706 (25.2%) IPR023591 (25.2%)" "Small ribosomal subunit protein uS2 (25.2%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25.2%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (25.2%)" EGLHLGPVQNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0016787 (97%) GO:0052689 (3%)" "hydrolase activity (97%) carboxylic ester hydrolase activity (3%)" "IPR002018 (21%) IPR019826 (19.8%) IPR029058 (19.8%)" "Carboxylesterase, type B (21%) Carboxylesterase type B, active site (19.8%) Alpha/Beta hydrolase fold (19.8%)" NQVLLTDNYTGDPATTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NMLNVGYLLTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.9%) "GO:0005737 (31.8%) GO:0016020 (0.4%)" GO:0008734 (33.9%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.9%) "cytoplasm (31.8%) membrane (0.4%)" L-aspartate oxidase activity (33.9%) "IPR005288 (16.9%) IPR015939 (16.9%) IPR037099 (16.8%)" "L-aspartate oxidase (16.9%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.9%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (16.8%)" GNLSFSTLNLVK Bacteria Bacteria 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.9%) GO:0009265 (16.9%)" GO:0031250 (16.9%) "GO:0004748 (16.9%) GO:0008998 (16.9%) GO:0005524 (15.5%)" "DNA replication (16.9%) 2'-deoxyribonucleotide biosynthetic process (16.9%)" anaerobic ribonucleoside-triphosphate reductase complex (16.9%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.9%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.9%) ATP binding (15.5%)" "IPR012833 (52%) IPR005144 (48%)" "Ribonucleoside-triphosphate reductase, anaerobic (52%) ATP-cone domain (48%)" QFAPEFLNR root "GO:0034605 (18.7%) GO:0006508 (12.4%) GO:0042026 (0.5%)" "GO:0005737 (18.6%) GO:0016020 (0.1%)" "GO:0005524 (18.7%) GO:0016887 (18.7%) GO:0008233 (12.4%)" "cellular response to heat (18.7%) proteolysis (12.4%) protein refolding (0.5%)" "cytoplasm (18.6%) membrane (0.1%)" "ATP binding (18.7%) ATP hydrolysis activity (18.7%) peptidase activity (12.4%)" "IPR050130 (9.6%) IPR019489 (9.6%) IPR003959 (9.5%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (9.6%) Clp ATPase, C-terminal (9.6%) ATPase, AAA-type, core (9.5%)" ETAYCLPLVSAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.6%) GO:0005737 (24.6%) "GO:0004821 (26.2%) GO:0005524 (24.6%)" histidyl-tRNA aminoacylation (24.6%) cytoplasm (24.6%) "histidine-tRNA ligase activity (26.2%) ATP binding (24.6%)" "IPR004154 (13.1%) IPR033656 (13.1%) IPR041715 (13.1%)" "Anticodon-binding (13.1%) Histidyl-anticodon-binding (13.1%) Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (13.1%)" LADAFTPLAK Bacteria Bacteria "1.3.8.1 (57.1%) 1.3.99.- (35.7%) 1.1.1.42 (7.1%)" "short-chain acyl-CoA dehydrogenase (57.1%) With other acceptors (35.7%) isocitrate dehydrogenase (NADP(+)) (7.1%)" "GO:0050660 (49.9%) GO:0016627 (32.1%) GO:0003995 (16.1%)" "flavin adenine dinucleotide binding (49.9%) oxidoreductase activity, acting on the CH-CH group of donors (32.1%) acyl-CoA dehydrogenase activity (16.1%)" "IPR020964 (9.7%) IPR052166 (9.7%) IPR006091 (9.7%)" "Acyl-CoA dehydrogenase, C-terminal (9.7%) Diverse substrate specificity acyl-CoA dehydrogenase (9.7%) Acyl-CoA oxidase/dehydrogenase, middle domain (9.7%)" GAETLGGMYAMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.5%) IPR023996 (13.5%) IPR023997 (13.5%)" "TonB-dependent receptor, plug domain (13.5%) TonB-dependent outer membrane protein, SusC/RagA (13.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.5%)" FADVSVLAR Pseudomonadati Bacteria Pseudomonadati 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (49.4%) GO:0016020 (1.2%) GO:0008233 (49.4%) proteolysis (49.4%) membrane (1.2%) peptidase activity (49.4%) "IPR001539 (49.4%) IPR051454 (49.4%) IPR036237 (1.2%)" "Peptidase U32 (49.4%) RNA and ubiquinone modification enzymes (49.4%) Xylose isomerase-like superfamily (1.2%)" ELVDLFNK root "2.6.1.9 (36.4%) 2.7.10.2 (25.5%) 3.1.21.3 (9.1%)" "histidinol-phosphate transaminase (36.4%) non-specific protein-tyrosine kinase (25.5%) type I site-specific deoxyribonuclease (9.1%)" "GO:0000105 (5.1%) GO:0006606 (2%) GO:0007165 (1.5%)" "GO:0005886 (6.1%) GO:0005829 (4.6%) GO:0005737 (3.6%)" "GO:0005524 (8.7%) GO:0004400 (5.1%) GO:0030170 (5.1%)" "L-histidine biosynthetic process (5.1%) protein import into nucleus (2%) signal transduction (1.5%)" "plasma membrane (6.1%) cytosol (4.6%) cytoplasm (3.6%)" "ATP binding (8.7%) histidinol-phosphate transaminase activity (5.1%) pyridoxal phosphate binding (5.1%)" "IPR027417 (5.1%) IPR001917 (4%) IPR004839 (4%)" "P-loop containing nucleoside triphosphate hydrolase (5.1%) Aminotransferase, class-II, pyridoxal-phosphate binding site (4%) Aminotransferase, class I/classII, large domain (4%)" LLELNAR root "6.3.5.5 (15.4%) 3.4.19.12 (14.1%) 6.3.4.16 (13.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (15.4%) ubiquitinyl hydrolase 1 (14.1%) carbamoyl-phosphate synthase (ammonia) (13.9%)" "GO:0009432 (9.6%) GO:0006541 (0.9%) GO:0006508 (0.8%)" "GO:0005737 (11.1%) GO:0005829 (1.4%) GO:0005634 (0.9%)" "GO:0005524 (15.5%) GO:0046872 (14.9%) GO:0018169 (9.6%)" "SOS response (9.6%) glutamine metabolic process (0.9%) proteolysis (0.8%)" "cytoplasm (11.1%) cytosol (1.4%) nucleus (0.9%)" "ATP binding (15.5%) metal ion binding (14.9%) ribosomal S6-glutamic acid ligase activity (9.6%)" "IPR011761 (14.4%) IPR039523 (9.6%) IPR011758 (9.2%)" "ATP-grasp fold (14.4%) Alpha-L-glutamate ligase-related protein, ATP-grasp domain (9.6%) Alpha-L-glutamate ligase-related protein (9.2%)" NSLLLFMVPGDTDDLKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (16.7%) GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" ribosome biogenesis (16.7%) cytoplasm (16.7%) "magnesium ion binding (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR006073 (12.5%) IPR006074 (12.5%) IPR006169 (12.5%)" "GTP binding domain (12.5%) GTP1/OBG, conserved site (12.5%) GTP1/OBG domain (12.5%)" GNALVTTVVNSQLSHAGTANDVLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (26.2%) IPR037066 (26.2%) IPR041700 (26.2%)" "Carboxypeptidase-like, regulatory domain superfamily (26.2%) TonB-dependent receptor, plug domain superfamily (26.2%) Outer membrane protein beta-barrel domain 3 (26.2%)" LFSPSLR root "2.7.11.1 (22.3%) 2.3.2.27 (19.1%) 2.7.6.1 (8.5%)" "non-specific serine/threonine protein kinase (22.3%) RING-type E3 ubiquitin transferase (19.1%) ribose-phosphate diphosphokinase (8.5%)" "GO:0000902 (7.6%) GO:0008360 (7.6%) GO:0006397 (1%)" "GO:0005737 (9.9%) GO:0016020 (7.1%) GO:0005634 (1.9%)" "GO:0005524 (9.4%) GO:0008270 (1.8%) GO:0016787 (1.2%)" "cell morphogenesis (7.6%) regulation of cell shape (7.6%) mRNA processing (1%)" "cytoplasm (9.9%) membrane (7.1%) nucleus (1.9%)" "ATP binding (9.4%) zinc ion binding (1.8%) hydrolase activity (1.2%)" "IPR043129 (6.5%) IPR004753 (6.4%) IPR056546 (6.4%)" "ATPase, nucleotide binding domain (6.5%) Cell shape determining protein MreB (6.4%) MreB/MamK-like (6.4%)" TWPNLVGNESAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.- (33.3%) 3.2.1.20 (33.3%) 3.2.1.22 (33.3%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (33.3%) alpha-glucosidase (33.3%) alpha-galactosidase (33.3%)" "GO:0030246 (56.1%) GO:0016787 (42.1%) GO:0004557 (0.9%)" "carbohydrate binding (56.1%) hydrolase activity (42.1%) alpha-galactosidase activity (0.9%)" "IPR019563 (14.5%) IPR029483 (14.5%) IPR029486 (14.5%)" "Glycosyl-hydrolase 97, catalytic domain (14.5%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.5%) Glycosyl-hydrolase 97, N-terminal domain (14.5%)" LVATLHDLQNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002539 (33.3%) IPR029069 (33.3%) IPR039375 (33.3%)" "MaoC-like dehydratase domain (33.3%) HotDog domain superfamily (33.3%) Nodulation protein N-like (33.3%)" FLNSQFATLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (10.7%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (10.7%)" "IPR004463 (14.7%) IPR010084 (14.7%) IPR013114 (14.7%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.7%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.7%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.7%)" TGLDLSTLSR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006352 (16.5%) GO:0006950 (0.1%) GO:0006355 (0.1%)" "GO:0000428 (16.5%) GO:0005739 (0.1%) GO:0032993 (0.1%)" "GO:0001216 (16.7%) GO:0016987 (16.7%) GO:0003677 (16.6%)" "DNA-templated transcription initiation (16.5%) response to stress (0.1%) regulation of DNA-templated transcription (0.1%)" "DNA-directed RNA polymerase complex (16.5%) mitochondrion (0.1%) protein-DNA complex (0.1%)" "DNA-binding transcription activator activity (16.7%) sigma factor activity (16.7%) DNA binding (16.6%)" "IPR000394 (24.9%) IPR007634 (24.9%) IPR007046 (24.6%)" "RNA polymerase sigma factor 54 (24.9%) RNA polymerase sigma factor 54, DNA-binding (24.9%) RNA polymerase sigma factor 54, core-binding domain (24.6%)" KLNVTAPYQVLPEHLDLDVTELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" KGELEEQLFFSSLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.6%) IPR050220 (20.6%) IPR013757 (19.6%)" "DNA topoisomerase, type IIA, domain A (20.6%) Type II DNA Topoisomerases (20.6%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.6%)" LDSWGSHEFEAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (33.9%) "GO:0004553 (33.9%) GO:0030246 (32.1%)" carbohydrate metabolic process (33.9%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.9%) carbohydrate binding (32.1%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" YNFNAGPSMLPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20%) GO:0008615 (20%)" GO:0005737 (20%) "GO:0004648 (20%) GO:0030170 (20%)" "L-serine biosynthetic process (20%) pyridoxine biosynthetic process (20%)" cytoplasm (20%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20%) pyridoxal phosphate binding (20%)" "IPR000192 (19.2%) IPR022278 (19.2%) IPR015421 (18.6%)" "Aminotransferase class V domain (19.2%) Phosphoserine aminotransferase (19.2%) Pyridoxal phosphate-dependent transferase, major domain (18.6%)" LYFPVDTENGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (26.4%) IPR017853 (25%) IPR045857 (25%)" "Glycosyl hydrolase family 13, catalytic domain (26.4%) Glycoside hydrolase superfamily (25%) Oligo-1,6-glucosidase, domain 2 (25%)" VVDVLTPK root "6.3.4.4 (82.1%) 7.1.3.1 (12.7%) 1.11.1.6 (5.2%)" "adenylosuccinate synthase (82.1%) H(+)-exporting diphosphatase (12.7%) catalase (5.2%)" "GO:0044208 (13.9%) GO:0046040 (13.9%) GO:0006979 (0.9%)" "GO:0005737 (13.9%) GO:0012505 (2.3%) GO:0016020 (2.3%)" "GO:0004019 (13.9%) GO:0005525 (13.9%) GO:0000287 (13.5%)" "'de novo' AMP biosynthetic process (13.9%) IMP metabolic process (13.9%) response to oxidative stress (0.9%)" "cytoplasm (13.9%) endomembrane system (2.3%) membrane (2.3%)" "adenylosuccinate synthase activity (13.9%) GTP binding (13.9%) magnesium ion binding (13.5%)" "IPR001114 (12.8%) IPR027417 (12.8%) IPR033128 (12.8%)" "Adenylosuccinate synthetase (12.8%) P-loop containing nucleoside triphosphate hydrolase (12.8%) Adenylosuccinate synthase, active site (12.8%)" TGSLLMESAADTSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015744 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) succinate transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) "IPR010619 (33.3%) IPR024528 (33.3%) IPR050539 (33.3%)" "Threonine/serine exporter-like, N-terminal domain (33.3%) Threonine/Serine exporter, ThrE (33.3%) ThrE Dicarboxylate/Amino Acid Exporter (33.3%)" LLHGDLDLTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (36.4%) IPR012944 (36.4%) IPR033985 (27.3%)" "Tetratricopeptide-like helical domain superfamily (36.4%) RagB/SusD domain (36.4%) SusD-like, N-terminal (27.3%)" ANAWSTYTAEFYNMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) NKLDELNMENPWQSSNWSGSTLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (36%) GO:0009279 (64%) iron ion transport (36%) cell outer membrane (64%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MRDELVELGLVPPVAEWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006108 (33.3%) "GO:0016615 (33.3%) GO:0016616 (33.3%)" malate metabolic process (33.3%) "malate dehydrogenase activity (33.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (33.3%)" "IPR001236 (16.7%) IPR001557 (16.7%) IPR010945 (16.7%)" "Lactate/malate dehydrogenase, N-terminal (16.7%) L-lactate/malate dehydrogenase (16.7%) Malate dehydrogenase, type 2 (16.7%)" NVFTANVPLGLGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR045743 (50.7%) IPR011250 (49.3%)" "Domain of unknown function DUF6089 (50.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (49.3%)" SGGSVYYRPQVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (47.8%) GO:0005737 (47.8%)" GO:0016787 (4.3%) "extracellular region (47.8%) cytoplasm (47.8%)" hydrolase activity (4.3%) "IPR028994 (19.7%) IPR003284 (14.5%) IPR006530 (13.2%)" "Integrin alpha, N-terminal (19.7%) Salmonella virulence plasmid 65kDa B protein (14.5%) YD repeat (13.2%)" NAEGESLSQFWGYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VPTTLYR root "3.1.3.27 (19.2%) 2.4.1.25 (11.5%) 3.1.1.3 (11.5%)" "phosphatidylglycerophosphatase (19.2%) 4-alpha-glucanotransferase (11.5%) triacylglycerol lipase (11.5%)" "GO:0005980 (21%) GO:0006508 (1.3%) GO:0048364 (0.7%)" "GO:0016020 (2.2%) GO:0005634 (1.3%) GO:0005886 (1.1%)" "GO:0004134 (21%) GO:0004135 (21%) GO:0005524 (1.5%)" "glycogen catabolic process (21%) proteolysis (1.3%) root development (0.7%)" "membrane (2.2%) nucleus (1.3%) plasma membrane (1.1%)" "4-alpha-glucanotransferase activity (21%) amylo-alpha-1,6-glucosidase activity (21%) ATP binding (1.5%)" "IPR024742 (13.1%) IPR010401 (13.1%) IPR032790 (13.1%)" "Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (13.1%) Glycogen debranching enzyme (13.1%) Glycogen debranching enzyme, C-terminal (13.1%)" DGFVQLANLFEETAANEKEHAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005506 (46.4%) GO:0016491 (46.4%) GO:0016692 (3.6%)" "iron ion binding (46.4%) oxidoreductase activity (46.4%) NADH peroxidase activity (3.6%)" "IPR003251 (14.7%) IPR009040 (14.7%) IPR048574 (14.7%)" "Rubrerythrin, diiron-binding domain (14.7%) Ferritin-like diiron domain (14.7%) Rubrerythrin, rubredoxin-like domain (14.7%)" NKEMWQAGVTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21.2%) GO:0009099 (21.2%)" "GO:0004455 (21.2%) GO:0046872 (21.2%) GO:0016853 (15.4%)" "isoleucine biosynthetic process (21.2%) L-valine biosynthetic process (21.2%)" "ketol-acid reductoisomerase activity (21.2%) metal ion binding (21.2%) isomerase activity (15.4%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" NLNAYTAVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (34.2%) "GO:0004222 (34.2%) GO:0046872 (31.5%)" proteolysis (34.2%) "metalloendopeptidase activity (34.2%) metal ion binding (31.5%)" "IPR001431 (20.3%) IPR007863 (20.3%) IPR011765 (20.3%)" "Peptidase M16, zinc-binding site (20.3%) Peptidase M16, C-terminal (20.3%) Peptidase M16, N-terminal (20.3%)" ADNYSQWYNDLVVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR004499 (11.5%) IPR002314 (11.1%) IPR004154 (11.1%)" "Proline-tRNA ligase, class IIa, archaeal-type (11.5%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Anticodon-binding (11.1%)" LEDMPFMADGRPVDMVLNPLGVPSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.8%) IPR007121 (7.8%) IPR007641 (7.8%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.8%) RNA polymerase, beta subunit, conserved site (7.8%) RNA polymerase Rpb2, domain 7 (7.8%)" KDLQLNLFEVK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (20.3%) "GO:0022627 (20.3%) GO:0005840 (0.1%)" "GO:0003735 (20.3%) GO:0019843 (20.1%) GO:0003729 (18.9%)" translation (20.3%) "cytosolic small ribosomal subunit (20.3%) ribosome (0.1%)" "structural constituent of ribosome (20.3%) rRNA binding (20.1%) mRNA binding (18.9%)" "IPR001351 (11.2%) IPR004044 (11.2%) IPR009019 (11.2%)" "Small ribosomal subunit protein uS3, C-terminal (11.2%) K Homology domain, type 2 (11.2%) K homology domain superfamily, prokaryotic type (11.2%)" TEGADGQLSGALSTTGDTLRPALQLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (65.9%) GO:0008959 (32.9%) GO:0016746 (1.2%)" "acetyltransferase activity (65.9%) phosphate acetyltransferase activity (32.9%) acyltransferase activity (1.2%)" "IPR002505 (16.8%) IPR050500 (16.8%) IPR004614 (16.6%)" "Phosphate acetyl/butaryl transferase (16.8%) Phosphate Acetyltransferase/Butyryltransferase (16.8%) Phosphate acetyltransferase (16.6%)" DKYLVMDENSK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.4%) GO:0005829 (17.4%) "GO:0004612 (17.4%) GO:0005524 (17.4%) GO:0046872 (17.3%)" gluconeogenesis (17.4%) cytosol (17.4%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.4%) ATP binding (17.4%) metal ion binding (17.3%)" "IPR001272 (25.1%) IPR008210 (25.1%) IPR013035 (24.9%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.1%) Phosphoenolpyruvate carboxykinase, N-terminal (25.1%) Phosphoenolpyruvate carboxykinase, C-terminal (24.9%)" MELPSFNALLQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (49.1%) "GO:0004467 (49.1%) GO:0016874 (1.8%)" membrane (49.1%) "long-chain fatty acid-CoA ligase activity (49.1%) ligase activity (1.8%)" "IPR000873 (26.1%) IPR020845 (25.2%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (26.1%) AMP-binding, conserved site (25.2%) ANL, N-terminal domain (24.3%)" LGPLQQQGNALGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.6%) "GO:0009279 (20.2%) GO:1990281 (20.2%)" "GO:0015288 (20.2%) GO:0015562 (20.2%) GO:0008233 (9.6%)" proteolysis (9.6%) "cell outer membrane (20.2%) efflux pump complex (20.2%)" "porin activity (20.2%) efflux transmembrane transporter activity (20.2%) peptidase activity (9.6%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" AREGYSFEEAYDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (15.9%) "GO:0004470 (16.8%) GO:0016616 (16.8%) GO:0016746 (16.8%)" malate metabolic process (15.9%) "malic enzyme activity (16.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.8%) acyltransferase activity (16.8%)" "IPR002505 (9.4%) IPR012301 (9.4%) IPR012302 (9.4%)" "Phosphate acetyl/butaryl transferase (9.4%) Malic enzyme, N-terminal domain (9.4%) Malic enzyme, NAD-binding (9.4%)" TVTVAYTLVKPTVASCTPAALTAGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" YASTLALNQSFYQYNPSLGDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" FFVQNEESKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.99.12 (100%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (100%) "GO:0009245 (25.3%) GO:0009244 (24.1%)" GO:0005886 (25.3%) "GO:0016740 (16.7%) GO:0043842 (8.6%)" "lipid A biosynthetic process (25.3%) lipopolysaccharide core region biosynthetic process (24.1%)" plasma membrane (25.3%) "transferase activity (16.7%) Kdo transferase activity (8.6%)" "IPR007507 (33.9%) IPR039901 (33.9%) IPR038107 (32.2%)" "3-deoxy-D-manno-octulosonic-acid transferase, N-terminal (33.9%) 3-deoxy-D-manno-octulosonic acid transferase (33.9%) 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily (32.2%)" HTDVNLPLMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NYDQANAVADAVLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (53.1%) IPR011990 (46.9%)" "Tetratricopeptide repeat (53.1%) Tetratricopeptide-like helical domain superfamily (46.9%)" YNFFYDNCTTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) "IPR025178 (50.8%) IPR057436 (49.2%)" "Lnb, N-terminal periplasmic domain (50.8%) Lnb-like, transmembrane domain (49.2%)" TTGVKEPLHYNVGDVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.40 (100%) pyruvate kinase (100%) "GO:0000287 (20%) GO:0004743 (20%) GO:0005524 (20%)" "magnesium ion binding (20%) pyruvate kinase activity (20%) ATP binding (20%)" "IPR001697 (11.6%) IPR015793 (11.6%) IPR015795 (11.6%)" "Pyruvate kinase (11.6%) Pyruvate kinase, barrel (11.6%) Pyruvate kinase, C-terminal (11.6%)" AGFNLLSDLREEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004824 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) lysine-tRNA ligase activity (16.7%)" "IPR002313 (12.7%) IPR004364 (12.7%) IPR004365 (12.7%)" "Lysine-tRNA ligase, class II (12.7%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.7%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.7%)" SNNLYNVLDASKDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LTTSVFGK root "GO:0006357 (4.5%) GO:0044718 (2.3%)" "GO:0009279 (72.7%) GO:0016592 (4.5%) GO:0016020 (2.3%)" "GO:0003712 (4.5%) GO:0005524 (2.3%) GO:0015344 (2.3%)" "regulation of transcription by RNA polymerase II (4.5%) siderophore transmembrane transport (2.3%)" "cell outer membrane (72.7%) mediator complex (4.5%) membrane (2.3%)" "transcription coregulator activity (4.5%) ATP binding (2.3%) siderophore uptake transmembrane transporter activity (2.3%)" "IPR036942 (68.1%) IPR014801 (4.3%) IPR002347 (2.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (68.1%) Mediator complex, subunit Med5, fungi (4.3%) Short-chain dehydrogenase/reductase SDR (2.1%)" EMLWLGGGAGMAPLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.7%) "GO:0005886 (16.5%) GO:0016020 (0.2%)" "GO:0016655 (16.7%) GO:0051537 (16.7%) GO:0009055 (16.5%)" sodium ion transport (16.7%) "plasma membrane (16.5%) membrane (0.2%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.7%) 2 iron, 2 sulfur cluster binding (16.7%) electron transfer activity (16.5%)" "IPR001433 (10.1%) IPR008333 (10.1%) IPR010205 (10.1%)" "Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%) Na(+)-translocating NADH-quinone reductase subunit F (10.1%)" QLNLNAVR root "3.2.1.23 (66.7%) 3.2.2.9 (27.1%) 3.2.2.16 (5.7%)" "beta-galactosidase (66.7%) adenosylhomocysteine nucleosidase (27.1%) methylthioadenosine nucleosidase (5.7%)" "GO:0005990 (15.1%) GO:0019284 (4.9%) GO:0019509 (4.9%)" "GO:0009341 (15.1%) GO:0005829 (4.9%) GO:0035869 (1.4%)" "GO:0004565 (15.1%) GO:0030246 (14.3%) GO:0008782 (4.9%)" "lactose catabolic process (15.1%) L-methionine salvage from S-adenosylmethionine (4.9%) L-methionine salvage from methylthioadenosine (4.9%)" "beta-galactosidase complex (15.1%) cytosol (4.9%) ciliary transition zone (1.4%)" "beta-galactosidase activity (15.1%) carbohydrate binding (14.3%) adenosylhomocysteine nucleosidase activity (4.9%)" "IPR006103 (6.7%) IPR050347 (6.7%) IPR006101 (6.6%)" "Glycoside hydrolase family 2, catalytic domain (6.7%) Bacterial Beta-galactosidase (6.7%) Glycoside hydrolase, family 2 (6.6%)" LTLPDVLDNSSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) IPR005543 (100%) PASTA domain (100%) YLVSLSK root "2.7.7.6 (74.3%) 1.5.5.1 (8.3%) 3.6.1.11 (1.7%)" "DNA-directed RNA polymerase (74.3%) electron-transferring-flavoprotein dehydrogenase (8.3%) exopolyphosphatase (1.7%)" "GO:0006351 (6%) GO:0016042 (4.8%) GO:0006886 (1.1%)" "GO:0000428 (6%) GO:0005576 (5%) GO:0016020 (2.6%)" "GO:0003677 (7.6%) GO:0008270 (6.3%) GO:0003899 (6%)" "DNA-templated transcription (6%) lipid catabolic process (4.8%) intracellular protein transport (1.1%)" "DNA-directed RNA polymerase complex (6%) extracellular region (5%) membrane (2.6%)" "DNA binding (7.6%) zinc ion binding (6.3%) DNA-directed RNA polymerase activity (6%)" "IPR007081 (3.8%) IPR045867 (3.8%) IPR007083 (3.7%)" "RNA polymerase Rpb1, domain 5 (3.8%) DNA-directed RNA polymerase, subunit beta-prime (3.8%) RNA polymerase Rpb1, domain 4 (3.7%)" FNTPAELR Bacteria Bacteria "GO:0006412 (18.9%) GO:0017148 (18.9%)" "GO:0022625 (18.9%) GO:0005886 (0.4%) GO:0031514 (0.4%)" "GO:0003729 (18.9%) GO:0003735 (18.9%) GO:0003700 (2.2%)" "translation (18.9%) negative regulation of translation (18.9%)" "cytosolic large ribosomal subunit (18.9%) plasma membrane (0.4%) motile cilium (0.4%)" "mRNA binding (18.9%) structural constituent of ribosome (18.9%) DNA-binding transcription factor activity (2.2%)" "IPR005822 (21.1%) IPR005823 (21.1%) IPR036899 (21.1%)" "Large ribosomal subunit protein uL13 (21.1%) Large ribosomal subunit protein uL13, bacteria (21.1%) Large ribosomal subunit protein uL13 superfamily (21.1%)" YNGQVQELTPAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.5%) GO:0008360 (14%) GO:0009252 (14%)" GO:0005737 (14%) "GO:0005524 (14.5%) GO:0008716 (14.5%) GO:0046872 (14.5%)" "cell wall organization (14.5%) regulation of cell shape (14%) peptidoglycan biosynthetic process (14%)" cytoplasm (14%) "ATP binding (14.5%) D-alanine-D-alanine ligase activity (14.5%) metal ion binding (14.5%)" "IPR000291 (14.4%) IPR005905 (14.4%) IPR011095 (14.4%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.4%) D-alanine--D-alanine ligase (14.4%) D-alanine--D-alanine ligase, C-terminal (14.4%)" MVSYFGR root "1.3.5.2 (50%) 2.5.1.18 (50%)" "dihydroorotate dehydrogenase (quinone) (50%) glutathione transferase (50%)" "GO:0044718 (25.3%) GO:0009306 (2%) GO:0044780 (2%)" "GO:0009279 (37.4%) GO:0005886 (2%) GO:0005737 (0.5%)" "GO:0015344 (25.3%) GO:0003676 (0.5%) GO:0004152 (0.5%)" "siderophore transmembrane transport (25.3%) protein secretion (2%) bacterial-type flagellum assembly (2%)" "cell outer membrane (37.4%) plasma membrane (2%) cytoplasm (0.5%)" "siderophore uptake transmembrane transporter activity (25.3%) nucleic acid binding (0.5%) dihydroorotate dehydrogenase activity (0.5%)" "IPR023996 (13.4%) IPR039426 (13.4%) IPR012910 (13.2%)" "TonB-dependent outer membrane protein, SusC/RagA (13.4%) TonB-dependent receptor-like (13.4%) TonB-dependent receptor, plug domain (13.2%)" NLSELAPGTFQHSLTVGNLAAELANR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (94.6%) GO:0016787 (5.4%) membrane (94.6%) hydrolase activity (5.4%) "IPR003607 (16.7%) IPR006674 (16.7%) IPR006675 (16.7%)" "HD/PDEase domain (16.7%) HD domain (16.7%) HDIG domain (16.7%)" VTEHQVVEGTVLSVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" EGSLLKPLDDLQLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016798 (48.9%) GO:0030246 (48.9%) GO:0016787 (2.1%)" "hydrolase activity, acting on glycosyl bonds (48.9%) carbohydrate binding (48.9%) hydrolase activity (2.1%)" "IPR019563 (12.8%) IPR029483 (12.8%) IPR029486 (12.8%)" "Glycosyl-hydrolase 97, catalytic domain (12.8%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (12.8%) Glycosyl-hydrolase 97, N-terminal domain (12.8%)" TFATGLAGFSHVVDSLSALK Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.6%) "GO:0005829 (33.5%) GO:0016020 (0.1%)" "GO:0008861 (33.5%) GO:0016829 (0.4%)" glucose metabolic process (32.6%) "cytosol (33.5%) membrane (0.1%)" "formate C-acetyltransferase activity (33.5%) lyase activity (0.4%)" "IPR004184 (20.2%) IPR050244 (20.2%) IPR001150 (20.1%)" "Pyruvate formate lyase domain (20.2%) Autonomous Glycyl Radical Cofactor (20.2%) Glycine radical domain (20.1%)" RAELQNFQYDAHTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004818 (16.7%) GO:0005524 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR000924 (10%) IPR001412 (10%) IPR004527 (10%)" "Glutamyl/glutaminyl-tRNA synthetase (10%) Aminoacyl-tRNA synthetase, class I, conserved site (10%) Glutamate-tRNA ligase, bacterial/mitochondrial (10%)" EAGADYVGLDEYVEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (17%) GO:0006417 (16%)" GO:0015934 (17%) "GO:0003735 (17%) GO:0019843 (17%) GO:0000049 (16%)" "translation (17%) regulation of translation (16%)" large ribosomal subunit (17%) "structural constituent of ribosome (17%) rRNA binding (17%) tRNA binding (16%)" "IPR005878 (17.2%) IPR023673 (17.2%) IPR028364 (17.2%)" "Large ribosomal subunit protein uL1, bacteria (17.2%) Large ribosomal subunit protein uL1, conserved site (17.2%) Ribosomal protein uL1/ribosomal biogenesis protein (17.2%)" VMNLPFK root "2.1.2.3 (87.3%) 3.5.4.10 (6.3%) 2.5.1.19 (3.8%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (87.3%) IMP cyclohydrolase (6.3%) 3-phosphoshikimate 1-carboxyvinyltransferase (3.8%)" "GO:0006189 (20.3%) GO:0008652 (0.6%) GO:0009073 (0.6%)" "GO:0005829 (20.3%) GO:0000785 (1.1%) GO:0005634 (1.1%)" "GO:0003937 (20.3%) GO:0004643 (20.3%) GO:0003677 (1.3%)" "'de novo' IMP biosynthetic process (20.3%) amino acid biosynthetic process (0.6%) aromatic amino acid family biosynthetic process (0.6%)" "cytosol (20.3%) chromatin (1.1%) nucleus (1.1%)" "IMP cyclohydrolase activity (20.3%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (20.3%) DNA binding (1.3%)" "IPR002695 (18.7%) IPR016193 (18.3%) IPR024051 (18.3%)" "Bifunctional purine biosynthesis protein PurH-like (18.7%) Cytidine deaminase-like (18.3%) AICAR transformylase, duplicated domain superfamily (18.3%)" DVLFLDKGENVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (34.5%) IPR043148 (32.8%) IPR051612 (32.8%)" "CDP-glycerol glycerophosphotransferase (34.5%) CDP-glycerol glycerophosphotransferase, C-terminal domain (32.8%) Teichoic Acid Biosynthesis Enzymes (32.8%)" QLLGLVCAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0002181 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" cytoplasmic translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000702 (20.2%) IPR002358 (20.2%) IPR020040 (20.2%)" "Large ribosomal subunit protein uL6-like (20.2%) Large ribosomal subunit protein uL6, conserved site (20.2%) Large ribosomal subunit protein uL6, alpha-beta domain (20.2%)" VLQVAANSVAEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.4%) IPR046357 (25.5%) IPR027304 (24.5%)" "Periplasmic chaperone PpiD (26.4%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.5%) Trigger factor/SurA domain superfamily (24.5%)" TLDGDLKNEQLETSFGFDTACK Pseudomonadati Bacteria Pseudomonadati 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.4%) GO:0006002 (13.6%)" GO:0005829 (14.4%) "GO:0003872 (14.4%) GO:0005524 (14.4%) GO:0046872 (14.4%)" "response to glucose (14.4%) fructose 6-phosphate metabolic process (13.6%)" cytosol (14.4%) "6-phosphofructokinase activity (14.4%) ATP binding (14.4%) metal ion binding (14.4%)" "IPR000023 (25.6%) IPR011183 (25.6%) IPR035966 (24.7%)" "Phosphofructokinase domain (25.6%) Pyrophosphate-dependent phosphofructokinase PfpB (25.6%) Phosphofructokinase superfamily (24.7%)" QLGEQLTQPLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (25.5%) IPR017932 (25.5%) IPR029055 (24.5%)" "Phosphoribosyltransferase domain (25.5%) Glutamine amidotransferase type 2 domain (25.5%) Nucleophile aminohydrolases, N-terminal (24.5%)" MLKDELLLPFVDLK Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.1%) GO:0006102 (20.1%)" "GO:0004450 (20.1%) GO:0000287 (19.5%) GO:0051287 (19.5%)" "tricarboxylic acid cycle (20.1%) isocitrate metabolic process (20.1%)" "isocitrate dehydrogenase (NADP+) activity (20.1%) magnesium ion binding (19.5%) NAD binding (19.5%)" "IPR004790 (33.7%) IPR024084 (33.7%) IPR019818 (32.6%)" "Isocitrate dehydrogenase NADP-dependent (33.7%) Isopropylmalate dehydrogenase-like domain (33.7%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.6%)" DVACDWDDSKYLEAEPAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (50.6%) GO:0016787 (49.4%)" "carbohydrate binding (50.6%) hydrolase activity (49.4%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" HVQNLTPYGPVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) CSNGEPLGYFWGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" QMWDNDVVEKDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.37 (66.7%) 3.2.1.55 (33.3%)" "xylan 1,4-beta-xylosidase (66.7%) non-reducing end alpha-L-arabinofuranosidase (33.3%)" "GO:0045493 (48.3%) GO:0005975 (1.7%)" "GO:0004553 (46.7%) GO:0009044 (3.3%)" "xylan catabolic process (48.3%) carbohydrate metabolic process (1.7%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (46.7%) xylan 1,4-beta-xylosidase activity (3.3%)" "IPR006710 (33.7%) IPR052176 (33.7%) IPR023296 (32.6%)" "Glycoside hydrolase, family 43 (33.7%) Glycosyl Hydrolase Family 43 Enzymes (33.7%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.6%)" AKPGLFNEWLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (50%) GO:0016881 (50%) cytoplasm (50%) acid-amino acid ligase activity (50%) "IPR004993 (33.3%) IPR055377 (33.3%) IPR055378 (33.3%)" "GH3 family (33.3%) GH3, middle domain (33.3%) GH3, C-terminal domain (33.3%)" NVSNPNLMFGQEGGEHAETLDSELMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QNPLTSLKDQNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (20.7%) GO:0009636 (19.6%) GO:0043418 (19.6%)" GO:0005737 (19.6%) GO:0070005 (20.7%) "proteolysis (20.7%) response to toxic substance (19.6%) homocysteine catabolic process (19.6%)" cytoplasm (19.6%) cysteine-type aminopeptidase activity (20.7%) "IPR004134 (32.8%) IPR038765 (31%) IPR000169 (25.9%)" "Peptidase C1B, bleomycin hydrolase (32.8%) Papain-like cysteine peptidase superfamily (31%) Cysteine peptidase, cysteine active site (25.9%)" LAPQLTMADGWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (28.9%) GO:0009279 (42.2%) GO:0015344 (28.9%) siderophore transmembrane transport (28.9%) cell outer membrane (42.2%) siderophore uptake transmembrane transporter activity (28.9%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" RFNTSVNLAPSFLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (14.5%) IPR023996 (14.5%) IPR039426 (14.5%)" "TonB-dependent receptor-like, beta-barrel (14.5%) TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like (14.5%)" DLDPDVDLNGYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" LAAPQLTGTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) SVTLEPALYYDQSFKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR036709 (42.9%) IPR011250 (28.6%) IPR027385 (28.6%)" "Autotransporter beta-domain superfamily (42.9%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (28.6%) Outer membrane protein, beta-barrel domain (28.6%)" SSLLNMLCNHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0000917 (33.3%) "GO:0005525 (33.3%) GO:0046872 (33.3%)" division septum assembly (33.3%) "GTP binding (33.3%) metal ion binding (33.3%)" "IPR006073 (25.2%) IPR019987 (25.2%) IPR030393 (25.2%)" "GTP binding domain (25.2%) GTP-binding protein, ribosome biogenesis, YsxC (25.2%) EngB-type guanine nucleotide-binding (G) domain (25.2%)" MHVATSTLDR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (26.3%) GO:0071555 (26.3%)" "GO:0016758 (26.3%) GO:0016798 (21%)" "carbohydrate metabolic process (26.3%) cell wall organization (26.3%)" "hexosyltransferase activity (26.3%) hydrolase activity, acting on glycosyl bonds (21%)" "IPR007184 (34%) IPR028583 (34%) IPR023296 (32.1%)" "Mannoside phosphorylase (34%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (34%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.1%)" VLAMGPNSLVGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (9.2%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (9.2%)" "IPR004463 (14.8%) IPR010084 (14.8%) IPR013114 (14.8%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.8%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.8%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%)" FLKEDMGYTGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (38.5%) "GO:0004556 (30.8%) GO:0043169 (30.8%)" carbohydrate metabolic process (38.5%) "alpha-amylase activity (30.8%) cation binding (30.8%)" "IPR006047 (38.5%) IPR006046 (30.8%) IPR017853 (30.8%)" "Glycosyl hydrolase family 13, catalytic domain (38.5%) Alpha amylase (30.8%) Glycoside hydrolase superfamily (30.8%)" APLVTVMGHVDHGK root GO:0006413 (0%) "GO:0005737 (23.4%) GO:0005829 (1.5%)" "GO:0003743 (24.9%) GO:0005525 (24.9%) GO:0003924 (24.9%)" translational initiation (0%) "cytoplasm (23.4%) cytosol (1.5%)" "translation initiation factor activity (24.9%) GTP binding (24.9%) GTPase activity (24.9%)" "IPR015760 (8.9%) IPR000795 (8.9%) IPR005225 (8.9%)" "Translation initiation factor IF- 2 (8.9%) Translational (tr)-type GTP-binding domain (8.9%) Small GTP-binding domain (8.9%)" DLGMTPGEGAPLYFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025970 (33.3%) IPR033404 (33.3%) IPR033407 (33.3%)" "SusE outer membrane protein (33.3%) Domain of unknown function DUF5111 (33.3%) Domain of unknown function DUF5114 (33.3%)" ELGNDLPELYQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006974 (51.6%) GO:0016020 (48.4%) DNA damage response (51.6%) membrane (48.4%) "IPR007497 (33.3%) IPR016907 (33.3%) IPR052022 (33.3%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.3%) Uncharacterised conserved protein UCP029033, periplasmic protein (33.3%) 26 kDa periplasmic antigen-related (33.3%)" TGCGALEALMQGQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" GO:0005945 (9.1%) "GO:0003872 (9.1%) GO:0005524 (9.1%) GO:0016208 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" 6-phosphofructokinase complex (9.1%) "6-phosphofructokinase activity (9.1%) ATP binding (9.1%) AMP binding (9.1%)" "IPR000023 (17.2%) IPR015912 (17.2%) IPR022953 (17.2%)" "Phosphofructokinase domain (17.2%) Phosphofructokinase, conserved site (17.2%) ATP-dependent 6-phosphofructokinase (17.2%)" EVEVLDAQHALLGLDGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR001206 (20.5%) IPR045540 (20.5%) IPR050187 (20.5%)" "Diacylglycerol kinase, catalytic domain (20.5%) YegS/DAGK, C-terminal domain (20.5%) Lipid Phosphate Formation and Regulation (20.5%)" SVEAFKNPDVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" LADWLLDMGPEGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) GO:0006289 (12.5%) "GO:0005737 (12.5%) GO:0009380 (12.5%)" "GO:0003677 (12.5%) GO:0004518 (12.5%) GO:0005524 (12.5%)" nucleotide-excision repair (12.5%) "cytoplasm (12.5%) excinuclease repair complex (12.5%)" "DNA binding (12.5%) nuclease activity (12.5%) ATP binding (12.5%)" "IPR003439 (14.6%) IPR004602 (14.6%) IPR017871 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) UvrABC system subunit A (14.6%) ABC transporter-like, conserved site (14.6%)" LCSVLSGGER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0006412 (12.6%) GO:0045900 (12.6%)" GO:0005737 (12.6%) "GO:0000049 (12.6%) GO:0005524 (12.6%) GO:0016887 (12.6%)" "translation (12.6%) negative regulation of translational elongation (12.6%)" cytoplasm (12.6%) "tRNA binding (12.6%) ATP binding (12.6%) ATP hydrolysis activity (12.6%)" "IPR003439 (16.7%) IPR003593 (16.7%) IPR017871 (16.7%)" "ABC transporter-like, ATP-binding domain (16.7%) AAA+ ATPase domain (16.7%) ABC transporter-like, conserved site (16.7%)" SGAAPLTHFDTTLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.5%) IPR014030 (14.5%) IPR014031 (14.5%)" "Beta-ketoacyl synthase (14.5%) Beta-ketoacyl synthase-like, N-terminal (14.5%) Beta-ketoacyl synthase, C-terminal (14.5%)" FQNDPCLMNLWVHDGSK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (33.9%) IPR050337 (33.9%) IPR036237 (32.1%)" "Rhamnose isomerase (33.9%) L-rhamnose isomerase (33.9%) Xylose isomerase-like superfamily (32.1%)" YSVLVGSR root "GO:0000226 (11.8%) GO:0035556 (11.8%) GO:0015677 (2.9%)" "GO:0005737 (11.8%) GO:0009279 (10.3%) GO:0005886 (2.9%)" "GO:0004674 (11.8%) GO:0005524 (11.8%) GO:0008823 (2.9%)" "microtubule cytoskeleton organization (11.8%) intracellular signal transduction (11.8%) copper ion import (2.9%)" "cytoplasm (11.8%) cell outer membrane (10.3%) plasma membrane (2.9%)" "protein serine/threonine kinase activity (11.8%) ATP binding (11.8%) cupric reductase (NADH) activity (2.9%)" "IPR000719 (10.7%) IPR008271 (10.7%) IPR011009 (10.7%)" "Protein kinase domain (10.7%) Serine/threonine-protein kinase, active site (10.7%) Protein kinase-like domain superfamily (10.7%)" GWETADLEQPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" VAGTNTGTVTDVDGNFSLNVPAGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33%) GO:0009279 (34%) GO:0015344 (33%) siderophore transmembrane transport (33%) cell outer membrane (34%) siderophore uptake transmembrane transporter activity (33%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" VRPEQGLLAMR root 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) "GO:0009098 (19.9%) GO:0006097 (0.1%) GO:0006099 (0.1%)" GO:0005829 (19.9%) "GO:0000287 (19.9%) GO:0003862 (19.9%) GO:0051287 (19.9%)" "L-leucine biosynthetic process (19.9%) glyoxylate cycle (0.1%) tricarboxylic acid cycle (0.1%)" cytosol (19.9%) "magnesium ion binding (19.9%) 3-isopropylmalate dehydrogenase activity (19.9%) NAD binding (19.9%)" "IPR004429 (32.9%) IPR019818 (32.9%) IPR024084 (32.9%)" "Isopropylmalate dehydrogenase (32.9%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.9%) Isopropylmalate dehydrogenase-like domain (32.9%)" VSATGQLYGSVNAATVAEELAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.3%) IPR009027 (14.3%) IPR020069 (14.3%)" "Large ribosomal subunit protein bL9 (14.3%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.3%) Large ribosomal subunit protein bL9, C-terminal (14.3%)" LAAAGYLAK Bacteria Bacteria "GO:0009279 (86.7%) GO:0016020 (6.7%)" "GO:0016491 (3.3%) GO:0016787 (3.3%)" "cell outer membrane (86.7%) membrane (6.7%)" "oxidoreductase activity (3.3%) hydrolase activity (3.3%)" "IPR012944 (31.3%) IPR033985 (31.3%) IPR011990 (30.1%)" "RagB/SusD domain (31.3%) SusD-like, N-terminal (31.3%) Tetratricopeptide-like helical domain superfamily (30.1%)" YANVLLMK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" LAGVEHEFSSVPGVKEDVTNLLLNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR011773 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) DNA-directed RNA polymerase, alpha subunit (16.7%)" YSVLGGQFNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.1 (97.2%) 6.3.1.5 (2.8%)" "NAD(+) synthase (glutamine-hydrolyzing) (97.2%) NAD(+) synthase (2.8%)" GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.8%) IPR003694 (14.8%) IPR014445 (14.8%)" "Carbon-nitrogen hydrolase (14.8%) NAD(+) synthetase (14.8%) Glutamine-dependent NAD(+) synthetase (14.8%)" GDWNQSYLVTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024311 (100%) Lipocalin-like domain (100%) FATSDLNDLYRR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (16.5%) GO:0006281 (0%) GO:0006412 (0%)" "GO:0000428 (16.6%) GO:0005829 (3.3%) GO:0009507 (0%)" "GO:0003677 (16.5%) GO:0003899 (16.5%) GO:0000287 (14.8%)" "DNA-templated transcription (16.5%) DNA repair (0%) translation (0%)" "DNA-directed RNA polymerase complex (16.6%) cytosol (3.3%) chloroplast (0%)" "DNA binding (16.5%) DNA-directed RNA polymerase activity (16.5%) magnesium ion binding (14.8%)" "IPR007080 (9.6%) IPR045867 (9.6%) IPR006592 (9.4%)" "RNA polymerase Rpb1, domain 1 (9.6%) DNA-directed RNA polymerase, subunit beta-prime (9.6%) RNA polymerase, N-terminal (9.4%)" ADGLDTGLYELQLLEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" VVYQDLVK root "5.4.2.12 (99.8%) 5.4.2.1 (0.2%)" "phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (99.8%) Transferred entry: 5.4.2.11 and 5.4.2.12 (0.2%)" "GO:0006007 (19.7%) GO:0006096 (19.6%) GO:0070897 (0.1%)" "GO:0005829 (19.7%) GO:0016460 (0.2%) GO:0005634 (0.1%)" "GO:0004619 (19.7%) GO:0030145 (19.7%) GO:0005509 (0.2%)" "glucose catabolic process (19.7%) glycolytic process (19.6%) transcription preinitiation complex assembly (0.1%)" "cytosol (19.7%) myosin II complex (0.2%) nucleus (0.1%)" "phosphoglycerate mutase activity (19.7%) manganese ion binding (19.7%) calcium ion binding (0.2%)" "IPR005995 (19.8%) IPR006124 (19.8%) IPR011258 (19.8%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (19.8%) Metalloenzyme (19.8%) BPG-independent PGAM, N-terminal (19.8%)" MDVDWSDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (16.9%) IPR019998 (16.9%) IPR028053 (16.9%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (16.9%) Membrane insertase YidC (16.9%) Membrane insertase YidC, N-terminal (16.9%)" VDPFQVLDQEGVGQLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (98.4%) 2.7.-.- (1.6%)" "pyruvate, phosphate dikinase (98.4%) Transferring phosphorus-containing groups (1.6%)" "GO:0050242 (25.3%) GO:0005524 (24.9%) GO:0016301 (24.9%)" "pyruvate, phosphate dikinase activity (25.3%) ATP binding (24.9%) kinase activity (24.9%)" "IPR000121 (10.1%) IPR010121 (10.1%) IPR015813 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate, phosphate dikinase (10.1%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.1%)" QLTPHPWDALDENLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.4%) IPR012340 (24.4%) IPR035104 (24.4%)" "S1 domain (24.4%) Nucleic acid-binding, OB-fold (24.4%) Ribosomal protein S1-like (24.4%)" EQLAQEVAQLVAAGGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.5.1.5 (50%) 3.5.4.9 (50%)" "methylenetetrahydrofolate dehydrogenase (NADP(+)) (50%) methenyltetrahydrofolate cyclohydrolase (50%)" "GO:0035999 (14.6%) GO:0000105 (13.8%) GO:0006164 (13.8%)" GO:0005829 (14.6%) "GO:0004477 (14.6%) GO:0004488 (14.6%)" "tetrahydrofolate interconversion (14.6%) L-histidine biosynthetic process (13.8%) purine nucleotide biosynthetic process (13.8%)" cytosol (14.6%) "methenyltetrahydrofolate cyclohydrolase activity (14.6%) methylenetetrahydrofolate dehydrogenase (NADP+) activity (14.6%)" "IPR000672 (16.7%) IPR020630 (16.7%) IPR020631 (16.7%)" "Tetrahydrofolate dehydrogenase/cyclohydrolase (16.7%) Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain (16.7%) Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain (16.7%)" RLEFVGEGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.6%) IPR012944 (33.6%) IPR033985 (32.8%)" "Tetratricopeptide-like helical domain superfamily (33.6%) RagB/SusD domain (33.6%) SusD-like, N-terminal (32.8%)" ALFYYLADER Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0005737 (99.8%) GO:0003729 (0.2%) cytoplasm (99.8%) mRNA binding (0.2%) "IPR007557 (49.9%) IPR047767 (49.9%) IPR020018 (0.1%)" "PSP1, C-terminal (49.9%) PSP1-like (49.9%) Gliding motility-associated lipoprotein, GldH (0.1%)" MEDLDQLSR Pseudomonadati Bacteria Pseudomonadati 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.1%) GO:0009099 (16.1%)" GO:0005829 (17.2%) "GO:0000287 (16.1%) GO:0004160 (16.1%) GO:0051537 (16.1%)" "isoleucine biosynthetic process (16.1%) L-valine biosynthetic process (16.1%)" cytosol (17.2%) "magnesium ion binding (16.1%) dihydroxy-acid dehydratase activity (16.1%) 2 iron, 2 sulfur cluster binding (16.1%)" "IPR000581 (17.2%) IPR056740 (17.2%) IPR020558 (16.7%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.2%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.2%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.7%)" LGAYLLGVR Bacteria Bacteria 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (17.5%) GO:0019324 (17.5%) GO:0005975 (4.1%)" "GO:0005737 (17.5%) GO:0005886 (1%)" "GO:0008740 (17.5%) GO:0030145 (17.5%) GO:0030596 (3.1%)" "rhamnose catabolic process (17.5%) L-lyxose metabolic process (17.5%) carbohydrate metabolic process (4.1%)" "cytoplasm (17.5%) plasma membrane (1%)" "L-rhamnose isomerase activity (17.5%) manganese ion binding (17.5%) alpha-L-rhamnosidase activity (3.1%)" "IPR009308 (20%) IPR050337 (20%) IPR036237 (18.8%)" "Rhamnose isomerase (20%) L-rhamnose isomerase (20%) Xylose isomerase-like superfamily (18.8%)" TPEQLEGLR root "3.4.11.18 (98.3%) 2.3.1.89 (0.9%) 1.13.11.11 (0.3%)" "methionyl aminopeptidase (98.3%) tetrahydrodipicolinate N-acetyltransferase (0.9%) tryptophan 2,3-dioxygenase (0.3%)" "GO:0006508 (22.6%) GO:0031640 (0.2%) GO:0042742 (0.2%)" "GO:0005829 (0.5%) GO:0016020 (0.4%) GO:0022626 (0.2%)" "GO:0070006 (22.6%) GO:0004239 (22.4%) GO:0046914 (22%)" "proteolysis (22.6%) killing of cells of another organism (0.2%) defense response to bacterium (0.2%)" "cytosol (0.5%) membrane (0.4%) cytosolic ribosome (0.2%)" "metalloaminopeptidase activity (22.6%) initiator methionyl aminopeptidase activity (22.4%) transition metal ion binding (22%)" "IPR000994 (16.4%) IPR002467 (16.4%) IPR036005 (16.4%)" "Peptidase M24 (16.4%) Peptidase M24A, methionine aminopeptidase, subfamily 1 (16.4%) Creatinase/aminopeptidase-like (16.4%)" GQLDLDEQGFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.8.1.9 (100%) thioredoxin-disulfide reductase (NADPH) (100%) GO:0019430 (33.3%) GO:0005737 (33.3%) GO:0004791 (33.3%) removal of superoxide radicals (33.3%) cytoplasm (33.3%) thioredoxin-disulfide reductase (NADPH) activity (33.3%) "IPR005982 (20.3%) IPR008255 (20.3%) IPR023753 (20.3%)" "Thioredoxin reductase (20.3%) Pyridine nucleotide-disulphide oxidoreductase, class-II, active site (20.3%) FAD/NAD(P)-binding domain (20.3%)" ELMDELGLVK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (12.8%) IPR023996 (12.8%) IPR023997 (12.8%)" "TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.8%)" LVDVLDNGAR Bacteria Bacteria 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.8%) IPR022147 (14.8%) IPR052725 (14.8%)" "Glutamine synthetase, N-terminal domain (14.8%) Glutamine synthetase type III N-terminal (14.8%) Glutamine Synthetase Type-3 (14.8%)" FVDPSTGFLSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025393 (51.5%) IPR029044 (48.5%)" "Domain of unknown function DUF4301 (51.5%) Nucleotide-diphospho-sugar transferases (48.5%)" SASTSKDPVLYLQGLWPTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.4.21.107 (80%) 3.4.21.- (20%)" "peptidase Do (80%) Serine endopeptidases (20%)" GO:0006508 (49.1%) GO:0016020 (1.9%) GO:0004252 (49.1%) proteolysis (49.1%) membrane (1.9%) serine-type endopeptidase activity (49.1%) "IPR001478 (17.8%) IPR025926 (17.8%) IPR001940 (17.1%)" "PDZ domain (17.8%) PDZ-like domain (17.8%) Peptidase S1C (17.1%)" QQLGAAYAVTQLFYDNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009086 (20%) GO:0035999 (20%)" GO:0005829 (20%) "GO:0071949 (20%) GO:0004489 (17.8%) GO:0106312 (2.2%)" "methionine biosynthetic process (20%) tetrahydrofolate interconversion (20%)" cytosol (20%) "FAD binding (20%) methylenetetrahydrofolate reductase [NAD(P)H] activity (17.8%) methylenetetrahydrofolate reductase (NADH) activity (2.2%)" "IPR003171 (52.9%) IPR029041 (47.1%)" "Methylenetetrahydrofolate reductase-like, catalytic domain (52.9%) FAD-linked oxidoreductase-like (47.1%)" QTDQDWTNAVVSGSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (90.9%) "GO:0009055 (3%) GO:0020037 (3%) GO:0046872 (3%)" membrane (90.9%) "electron transfer activity (3%) heme binding (3%) metal ion binding (3%)" "IPR025874 (87.9%) IPR011990 (9.1%) IPR009056 (3%)" "Double zinc ribbon (87.9%) Tetratricopeptide-like helical domain superfamily (9.1%) Cytochrome c-like domain (3%)" QTPGFSGADLANVCNEAALLAAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (11.3%) GO:0030163 (10.7%) GO:0010467 (7.2%)" "GO:0005886 (10.7%) GO:0016020 (0.4%) GO:0031966 (0.1%)" "GO:0005524 (11.3%) GO:0004176 (11.3%) GO:0004222 (11.3%)" "proteolysis (11.3%) protein catabolic process (10.7%) gene expression (7.2%)" "plasma membrane (10.7%) membrane (0.4%) mitochondrial membrane (0.1%)" "ATP binding (11.3%) ATP-dependent peptidase activity (11.3%) metalloendopeptidase activity (11.3%)" "IPR041569 (10.2%) IPR050928 (10.2%) IPR000642 (10.2%)" "AAA ATPase, AAA+ lid domain (10.2%) ATP-dependent Zinc Metalloprotease (10.2%) Peptidase M41 (10.2%)" YDGYLNAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (93.3%) GO:0015483 (6.7%) cell outer membrane (93.3%) long-chain fatty acid transporting porin activity (6.7%) "IPR000531 (12.4%) IPR008969 (12.4%) IPR012910 (12.4%)" "TonB-dependent receptor-like, beta-barrel (12.4%) Carboxypeptidase-like, regulatory domain superfamily (12.4%) TonB-dependent receptor, plug domain (12.4%)" TVYEVLSQGNETLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0006412 (12.5%) GO:0045900 (12.5%)" GO:0005737 (12.5%) "GO:0000049 (12.5%) GO:0005524 (12.5%) GO:0016887 (12.5%)" "translation (12.5%) negative regulation of translational elongation (12.5%)" cytoplasm (12.5%) "tRNA binding (12.5%) ATP binding (12.5%) ATP hydrolysis activity (12.5%)" "IPR003439 (16.7%) IPR003593 (16.7%) IPR017871 (16.7%)" "ABC transporter-like, ATP-binding domain (16.7%) AAA+ ATPase domain (16.7%) ABC transporter-like, conserved site (16.7%)" MGNTVLLATVCAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.2%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.2%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR001247 (8%) IPR012162 (8%) IPR015847 (8%)" "Exoribonuclease, phosphorolytic domain 1 (8%) Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 2 (8%)" AVHAVDNCVKDVLEAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" NVEEGQTPSMLDTQLYLMTLSDKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (34.5%) IPR011042 (33.3%) IPR029058 (32.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.5%) Six-bladed beta-propeller, TolB-like (33.3%) Alpha/Beta hydrolase fold (32.2%)" DVDYWLK root "1.1.1.169 (25%) 2.3.1.165 (25%) 2.3.1.41 (25%)" "2-dehydropantoate 2-reductase (25%) 6-methylsalicylic acid synthase (25%) beta-ketoacyl-[acyl-carrier-protein] synthase I (25%)" "GO:0006633 (11.5%) GO:0071770 (10.6%) GO:0005975 (1.9%)" "GO:0005737 (11.5%) GO:0005886 (11.5%) GO:0009279 (4.8%)" "GO:0004312 (11.5%) GO:0031177 (11.5%) GO:0004315 (10.6%)" "fatty acid biosynthetic process (11.5%) DIM/DIP cell wall layer assembly (10.6%) carbohydrate metabolic process (1.9%)" "cytoplasm (11.5%) plasma membrane (11.5%) cell outer membrane (4.8%)" "fatty acid synthase activity (11.5%) phosphopantetheine binding (11.5%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (10.6%)" "IPR001227 (4.4%) IPR009081 (4.4%) IPR014030 (4.4%)" "Acyl transferase domain superfamily (4.4%) Phosphopantetheine binding ACP domain (4.4%) Beta-ketoacyl synthase-like, N-terminal (4.4%)" MLELAWEGVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.6%) IPR012944 (33.6%) IPR033985 (32.7%)" "Tetratricopeptide-like helical domain superfamily (33.6%) RagB/SusD domain (33.6%) SusD-like, N-terminal (32.7%)" LMGELVKDTAEATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) ELEGDMGDNVVGLQAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006281 (13%) GO:0006310 (13%) GO:0009432 (11.7%)" GO:0005829 (13%) "GO:0003697 (13%) GO:0005524 (13%) GO:0140664 (13%)" "DNA repair (13%) DNA recombination (13%) SOS response (11.7%)" cytosol (13%) "single-stranded DNA binding (13%) ATP binding (13%) ATP-dependent DNA damage sensor activity (13%)" "IPR013765 (11.8%) IPR020584 (11.8%) IPR020587 (11.8%)" "DNA recombination and repair protein RecA (11.8%) DNA recombination/repair protein RecA, conserved site (11.8%) DNA recombination and repair protein RecA, monomer-monomer interface (11.8%)" LYSTLENYWLQANTNQSQFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" YPEYHLLNLDK Bacteria Bacteria 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (49.8%) GO:0016020 (0.5%) GO:0008460 (49.8%) nucleotide-sugar metabolic process (49.8%) membrane (0.5%) dTDP-glucose 4,6-dehydratase activity (49.8%) "IPR036291 (34%) IPR005888 (31.8%) IPR001509 (20.1%)" "NAD(P)-binding domain superfamily (34%) dTDP-glucose 4,6-dehydratase (31.8%) NAD-dependent epimerase/dehydratase (20.1%)" LSLVDPESGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.4%) IPR006426 (14.4%) IPR017932 (14.4%)" "Asparagine synthase (14.4%) Asparagine synthase, glutamine-hydrolyzing (14.4%) Glutamine amidotransferase type 2 domain (14.4%)" SVCTLSSHDMPTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25.1%) GO:0005737 (25.1%) "GO:0004134 (25.1%) GO:2001070 (24.7%)" carbohydrate metabolic process (25.1%) cytoplasm (25.1%) "4-alpha-glucanotransferase activity (25.1%) starch binding (24.7%)" "IPR003385 (20.8%) IPR002044 (20.5%) IPR017853 (19.8%)" "Glycoside hydrolase, family 77 (20.8%) Carbohydrate binding module family 20 (20.5%) Glycoside hydrolase superfamily (19.8%)" TPLFMPVGTVGSVK Pseudomonadati Bacteria Pseudomonadati "2.4.2.29 (99.7%) 2.4.2.- (0.3%)" "tRNA-guanosine(34) preQ1 transglycosylase (99.7%) Pentosyltransferases (0.3%)" "GO:0002099 (28.2%) GO:0008616 (2%) GO:0006400 (1.7%)" "GO:0005829 (29.4%) GO:0005737 (0.5%)" "GO:0008479 (29.7%) GO:0046872 (8.1%) GO:0016757 (0.1%)" "tRNA wobble guanine modification (28.2%) tRNA queuosine(34) biosynthetic process (2%) tRNA modification (1.7%)" "cytosol (29.4%) cytoplasm (0.5%)" "tRNA-guanosine(34) queuine transglycosylase activity (29.7%) metal ion binding (8.1%) glycosyltransferase activity (0.1%)" "IPR002616 (25.5%) IPR036511 (25.3%) IPR004803 (25.1%)" "tRNA-guanine(15) transglycosylase-like (25.5%) Queuine tRNA-ribosyltransferase-like (25.3%) tRNA-guanine transglycosylase (25.1%)" VNLEANTVDVELAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015031 (50%) GO:0005886 (50%) protein transport (50%) plasma membrane (50%) IPR003849 (100%) Preprotein translocase YajC (100%) VVASTFADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0051301 (9.5%) GO:0032506 (4.8%)" "GO:0030428 (4.8%) GO:0032153 (4.8%)" GO:0042834 (76.2%) "cell division (9.5%) cytokinetic process (4.8%)" "cell septum (4.8%) cell division site (4.8%)" peptidoglycan binding (76.2%) "IPR007730 (48.5%) IPR036680 (48.5%) IPR052521 (3%)" "Sporulation-like domain (48.5%) Sporulation-like domain superfamily (48.5%) Bacterial cell division SPOR domain-containing protein (3%)" MDEVLFEEFK root "3.6.4.- (99.9%) 3.6.1.- (0.1%) 2.7.1.24 (0%)" "Acting on ATP; involved in cellular and subcellular movement (99.9%) In phosphorus-containing anhydrides (0.1%) dephospho-CoA kinase (0%)" "GO:0006353 (15%) GO:0055085 (0%) GO:0015937 (0%)" "GO:0005829 (10%) GO:0016020 (0%) GO:0005737 (0%)" "GO:0003723 (15%) GO:0005524 (15%) GO:0008186 (15%)" "DNA-templated transcription termination (15%) transmembrane transport (0%) coenzyme A biosynthetic process (0%)" "cytosol (10%) membrane (0%) cytoplasm (0%)" "RNA binding (15%) ATP binding (15%) ATP-dependent activity, acting on RNA (15%)" "IPR004665 (10.5%) IPR027417 (10.4%) IPR000194 (10.4%)" "Transcription termination factor Rho (10.5%) P-loop containing nucleoside triphosphate hydrolase (10.4%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.4%)" GLVTAMGHAPQAGLADPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.7%) GO:0006164 (0.6%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.6%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR055181 (11.5%) IPR010073 (11.1%) IPR010918 (11.1%)" "FGAR-AT, PurM N-terminal-like domain (11.5%) Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%)" KLLTGLAEVLGEAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.8%) GO:0005737 (24.8%) "GO:0004821 (24.8%) GO:0005524 (24.8%) GO:0004812 (1%)" histidyl-tRNA aminoacylation (24.8%) cytoplasm (24.8%) "histidine-tRNA ligase activity (24.8%) ATP binding (24.8%) aminoacyl-tRNA ligase activity (1%)" "IPR041715 (13%) IPR004154 (12.6%) IPR006195 (12.6%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (13%) Anticodon-binding (12.6%) Aminoacyl-tRNA synthetase, class II (12.6%)" NLLDSETLYHNQEALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.7%) GO:0005829 (16.7%) "GO:0003723 (16.7%) GO:0004831 (16.7%) GO:0005524 (16.7%)" tyrosyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "RNA binding (16.7%) tyrosine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (12.6%) IPR002305 (12.6%) IPR002307 (12.6%)" "Aminoacyl-tRNA synthetase, class I, conserved site (12.6%) Aminoacyl-tRNA synthetase, class Ic (12.6%) Tyrosine-tRNA ligase (12.6%)" TQLDFGFVLPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EAYGQGLWAPALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (17.3%) IPR051795 (17.3%) IPR041542 (16.9%)" "Glycoside hydrolase, family 43 (17.3%) Glycosyl Hydrolase Family 43 (17.3%) Beta-xylosidase, C-terminal Concanavalin A-like domain (16.9%)" NAYGEVDNLQR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.3%) GO:0009090 (17.3%) GO:0009088 (13.5%)" GO:0005829 (17.3%) "GO:0004072 (17.3%) GO:0005524 (17.3%)" "lysine biosynthetic process via diaminopimelate (17.3%) homoserine biosynthetic process (17.3%) threonine biosynthetic process (13.5%)" cytosol (17.3%) "aspartate kinase activity (17.3%) ATP binding (17.3%)" "IPR001048 (14%) IPR001341 (14%) IPR036393 (14%)" "Aspartate/glutamate/uridylate kinase (14%) Aspartate kinase (14%) Acetylglutamate kinase-like superfamily (14%)" MVDLFAEWQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR010870 (51.3%) IPR023614 (48.7%)" "Phosphate-selective porin O/P (51.3%) Porin domain superfamily (48.7%)" SAGFPLLK root "1.3.5.1 (25%) 1.3.99.1 (25%) 2.3.1.- (25%)" "succinate dehydrogenase (25%) Deleted entry (25%) Transferring groups other than amino-acyl groups (25%)" "GO:0009060 (20.5%) GO:0022904 (20.5%) GO:0006260 (2.6%)" GO:0016020 (1.3%) "GO:0009055 (20.5%) GO:0051537 (20.5%) GO:0046872 (5.1%)" "aerobic respiration (20.5%) respiratory electron transport chain (20.5%) DNA replication (2.6%)" membrane (1.3%) "electron transfer activity (20.5%) 2 iron, 2 sulfur cluster binding (20.5%) metal ion binding (5.1%)" "IPR006058 (10.7%) IPR009051 (10.7%) IPR012675 (10.7%)" "2Fe-2S ferredoxin, iron-sulphur binding site (10.7%) Alpha-helical ferredoxin (10.7%) Beta-grasp domain superfamily (10.7%)" GELLQPNAQPGDVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.9%) IPR012910 (13.9%) IPR023996 (13.9%)" "Carboxypeptidase-like, regulatory domain superfamily (13.9%) TonB-dependent receptor, plug domain (13.9%) TonB-dependent outer membrane protein, SusC/RagA (13.9%)" AVLPLDLPTLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.6%) IPR026263 (33.6%) IPR017850 (31.8%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.6%) Alkaline phosphatase, prokaryotic (33.6%) Alkaline-phosphatase-like, core domain superfamily (31.8%)" KLATSYPNLLR Pseudomonadati Bacteria Pseudomonadati 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20.1%) GO:0005737 (20.1%) "GO:0003879 (20.1%) GO:0005524 (20.1%) GO:0000287 (19.5%)" L-histidine biosynthetic process (20.1%) cytoplasm (20.1%) "ATP phosphoribosyltransferase activity (20.1%) ATP binding (20.1%) magnesium ion binding (19.5%)" "IPR001348 (14.6%) IPR013820 (14.6%) IPR011322 (14.1%)" "ATP phosphoribosyltransferase HisG (14.6%) ATP phosphoribosyltransferase, catalytic domain (14.6%) Nitrogen regulatory PII-like, alpha/beta (14.1%)" SQSADDNYQSLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0034605 (18.6%) GO:0042026 (17.4%) GO:0006508 (4.2%)" GO:0005737 (18.6%) "GO:0005524 (18.6%) GO:0016887 (18.6%) GO:0008233 (4.2%)" "cellular response to heat (18.6%) protein refolding (17.4%) proteolysis (4.2%)" cytoplasm (18.6%) "ATP binding (18.6%) ATP hydrolysis activity (18.6%) peptidase activity (4.2%)" "IPR003593 (8.5%) IPR003959 (8.5%) IPR004176 (8.5%)" "AAA+ ATPase domain (8.5%) ATPase, AAA-type, core (8.5%) Clp, repeat (R) N-terminal domain (8.5%)" EKLNAELEAMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21%) GO:0009099 (21%)" "GO:0004455 (21%) GO:0046872 (21%) GO:0016853 (16.1%)" "isoleucine biosynthetic process (21%) L-valine biosynthetic process (21%)" "ketol-acid reductoisomerase activity (21%) metal ion binding (21%) isomerase activity (16.1%)" "IPR000506 (17.3%) IPR013023 (17.3%) IPR013116 (17.3%)" "Ketol-acid reductoisomerase, C-terminal (17.3%) Ketol-acid reductoisomerase (17.3%) Ketol-acid reductoisomerase, N-terminal (17.3%)" WSNLMVTGAVEPTEENLTPWLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (66.7%) GO:0008675 (16.7%) GO:0008700 (16.7%)" "lyase activity (66.7%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (16.7%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (16.7%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" GSNNLLYVPASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (20%) IPR036942 (20%) IPR037066 (20%)" "Carboxypeptidase-like, regulatory domain superfamily (20%) TonB-dependent receptor-like, beta-barrel domain superfamily (20%) TonB-dependent receptor, plug domain superfamily (20%)" SDKLETLEAHTELTPEELVNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.-.-.- (100%) Translocases (100%) GO:0022900 (19%) "GO:0005886 (19%) GO:0016020 (1.2%)" "GO:0009055 (20.2%) GO:0046872 (20.2%) GO:0051539 (20.2%)" electron transport chain (19%) "plasma membrane (19%) membrane (1.2%)" "electron transfer activity (20.2%) metal ion binding (20.2%) 4 iron, 4 sulfur cluster binding (20.2%)" "IPR010208 (14.8%) IPR011538 (14.8%) IPR037225 (14.8%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.8%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.8%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily (14.8%)" DVLELDAMQTYTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (44.8%) IPR036942 (32.8%) IPR039426 (22.4%)" "TonB-dependent receptor-like, beta-barrel (44.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.8%) TonB-dependent receptor-like (22.4%)" VLGVGGGGGNAVNHMYR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0000917 (14.3%) GO:0043093 (14%) GO:0051258 (14%)" "GO:0005737 (14.4%) GO:0032153 (14.4%)" "GO:0003924 (14.4%) GO:0005525 (14.4%)" "division septum assembly (14.3%) FtsZ-dependent cytokinesis (14%) protein polymerization (14%)" "cytoplasm (14.4%) cell division site (14.4%)" "GTPase activity (14.4%) GTP binding (14.4%)" "IPR003008 (11.3%) IPR045061 (11.3%) IPR000158 (11.2%)" "Tubulin/FtsZ, GTPase domain (11.3%) Tubulin-like protein FtsZ/CetZ (11.3%) Cell division protein FtsZ (11.2%)" LYSTTEGYGVSYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006680 (33.3%) GO:0016020 (33.3%) GO:0004348 (33.3%) glucosylceramide catabolic process (33.3%) membrane (33.3%) glucosylceramidase activity (33.3%) "IPR001139 (20.4%) IPR033452 (20.4%) IPR033453 (20.4%)" "Glycoside hydrolase family 30 (20.4%) Glycosyl hydrolase family 30, beta sandwich domain (20.4%) Glycosyl hydrolase family 30, TIM-barrel domain (20.4%)" VYLLDELHTPDSSR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) GO:0005737 (25%) "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) cytoplasm (25%) "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR018236 (50%) IPR028923 (50%)" "SAICAR synthetase, conserved site (50%) SAICAR synthetase/ADE2, N-terminal (50%)" NGAVSDLDGNYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR037066 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent receptor, plug domain superfamily (13%)" DLTPASYNR root GO:0006508 (0.9%) "GO:0005762 (38.6%) GO:0016020 (21.1%)" "GO:0003735 (38.6%) GO:0008233 (0.9%)" proteolysis (0.9%) "mitochondrial large ribosomal subunit (38.6%) membrane (21.1%)" "structural constituent of ribosome (38.6%) peptidase activity (0.9%)" "IPR013870 (33.3%) IPR006665 (18.2%) IPR050330 (18.2%)" "Large ribosomal subunit protein mL54 (33.3%) OmpA-like domain (18.2%) Bacterial Outer Membrane Structural/Functional (18.2%)" LDGLNGGADTNESSAANSVVANTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (36%) GO:0009279 (64%) iron ion transport (36%) cell outer membrane (64%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" DLETYFPSALLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20%) IPR014721 (20%) IPR020568 (20%)" "Small ribosomal subunit protein uS9 (20%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (20%) Ribosomal protein uS5 domain 2-type superfamily (20%)" VYPTDANFFLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.9 (100%) histidinol-phosphate transaminase (100%) GO:0000105 (33.3%) "GO:0004400 (33.3%) GO:0030170 (33.3%)" L-histidine biosynthetic process (33.3%) "histidinol-phosphate transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (17.2%) IPR005861 (17.2%) IPR015421 (16.7%)" "Aminotransferase, class I/classII, large domain (17.2%) Histidinol-phosphate aminotransferase family (17.2%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" SQHADVLETLGDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (16.9%) GO:0045259 (16.9%)" "GO:0005524 (16.9%) GO:0043531 (16.9%) GO:0046933 (16.9%)" "plasma membrane (16.9%) proton-transporting ATP synthase complex (16.9%)" "ATP binding (16.9%) ADP binding (16.9%) proton-transporting ATP synthase activity, rotational mechanism (16.9%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" LPNPFMPDAPQR Bacteria Bacteria "1.1.1.- (85.7%) 1.1.1.57 (14.3%)" "With NAD(+) or NADP(+) as acceptor (85.7%) fructuronate reductase (14.3%)" "GO:0016616 (94.6%) GO:0008926 (3.6%) GO:0008866 (1.8%)" "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (94.6%) mannitol-1-phosphate 5-dehydrogenase activity (3.6%) fructuronate reductase activity (1.8%)" "IPR013118 (16.9%) IPR050988 (16.9%) IPR008927 (16.6%)" "Mannitol dehydrogenase, C-terminal (16.9%) Mannitol Dehydrogenase/Oxidoreductase (16.9%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.6%)" KLQEFASYNDSLEEVFENR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006351 (25%) GO:0000428 (25%) "GO:0003677 (25%) GO:0003899 (25%)" DNA-templated transcription (25%) DNA-directed RNA polymerase complex (25%) "DNA binding (25%) DNA-directed RNA polymerase activity (25%)" IPR006110 (100%) RNA polymerase, subunit omega/Rpo6/RPB6 (100%) QFEALDALYR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.1.1.- (100%) Methyltransferases (100%) GO:0005829 (50%) GO:0070043 (50%) cytosol (50%) rRNA (guanine-N7-)-methyltransferase activity (50%) "IPR003682 (50%) IPR029063 (50%)" "rRNA small subunit methyltransferase G (50%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (50%)" MPSQFDNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" LDPNMHVLDLVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.4 (100%) tripeptide aminopeptidase (100%) "GO:0006508 (16.5%) GO:0043171 (16.5%)" GO:0005829 (17%) "GO:0045148 (17%) GO:0008237 (16.5%) GO:0008270 (16.5%)" "proteolysis (16.5%) peptide catabolic process (16.5%)" cytosol (17%) "tripeptide aminopeptidase activity (17%) metallopeptidase activity (16.5%) zinc ion binding (16.5%)" "IPR002933 (20.7%) IPR001261 (20.1%) IPR010161 (20.1%)" "Peptidase M20 (20.7%) ArgE/DapE/ACY1/CPG2/YscS, conserved site (20.1%) Peptidase M20B, tripeptide aminopeptidase (20.1%)" GLVTDPSGEPVLGATVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (4%) GO:0009279 (92%) GO:0015344 (4%) siderophore transmembrane transport (4%) cell outer membrane (92%) siderophore uptake transmembrane transporter activity (4%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023997 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" TKDFTWTTDFNLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" EEVSLPWGGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0032790 (25.3%) "GO:0003746 (25.3%) GO:0005525 (25.3%) GO:0003924 (24.1%)" ribosome disassembly (25.3%) "translation elongation factor activity (25.3%) GTP binding (25.3%) GTPase activity (24.1%)" "IPR000640 (8%) IPR005517 (8%) IPR035649 (8%)" "Elongation factor EFG, domain V-like (8%) Translation elongation factor EFG/EF2, domain IV (8%) EFG, domain V (8%)" FSSAGVPR root 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0005975 (48.4%) GO:0019301 (0.5%) GO:0019324 (0.5%)" GO:0032993 (0.2%) "GO:0008422 (46.3%) GO:0004553 (2.1%) GO:0008740 (0.5%)" "carbohydrate metabolic process (48.4%) rhamnose catabolic process (0.5%) L-lyxose metabolic process (0.5%)" protein-DNA complex (0.2%) "beta-glucosidase activity (46.3%) hydrolase activity, hydrolyzing O-glycosyl compounds (2.1%) L-rhamnose isomerase activity (0.5%)" "IPR001764 (11.2%) IPR050288 (11.2%) IPR017853 (11.2%)" "Glycoside hydrolase, family 3, N-terminal (11.2%) Cellulose-degrading glycosyl hydrolase 3 (11.2%) Glycoside hydrolase superfamily (11.2%)" VLTTSADNTPLSLVATGAEYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025970 (33.3%) IPR033404 (33.3%) IPR033407 (33.3%)" "SusE outer membrane protein (33.3%) Domain of unknown function DUF5111 (33.3%) Domain of unknown function DUF5114 (33.3%)" LNVTAPYQVLPEHLDLDVTELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" SDELLLR root "7.2.2.6 (18.3%) 6.1.1.20 (14.3%) 6.5.1.1 (9%)" "P-type K(+) transporter (18.3%) phenylalanine--tRNA ligase (14.3%) DNA ligase (ATP) (9%)" "GO:0031146 (2.6%) GO:0006281 (2.2%) GO:0006310 (2.2%)" "GO:0005737 (3.4%) GO:0019005 (2.9%) GO:0005886 (2.7%)" "GO:0005524 (7.5%) GO:0000287 (2.4%) GO:0016887 (2%)" "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (2.6%) DNA repair (2.2%) DNA recombination (2.2%)" "cytoplasm (3.4%) SCF ubiquitin ligase complex (2.9%) plasma membrane (2.7%)" "ATP binding (7.5%) magnesium ion binding (2.4%) ATP hydrolysis activity (2%)" "IPR036047 (4.1%) IPR001810 (3.1%) IPR027417 (2.9%)" "F-box-like domain superfamily (4.1%) F-box domain (3.1%) P-loop containing nucleoside triphosphate hydrolase (2.9%)" TAADAAEALGLGLQAFCLPGSVADDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR025964 (100%) GGGtGRT protein (100%) VPESYTVTGEGYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" KNPEGANEVLNNLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.6%) GO:0009090 (17.6%) GO:0009088 (12%)" GO:0005829 (17.6%) "GO:0004072 (17.6%) GO:0005524 (17.6%)" "lysine biosynthetic process via diaminopimelate (17.6%) homoserine biosynthetic process (17.6%) threonine biosynthetic process (12%)" cytosol (17.6%) "aspartate kinase activity (17.6%) ATP binding (17.6%)" "IPR001048 (14.4%) IPR001341 (14.4%) IPR005260 (14.4%)" "Aspartate/glutamate/uridylate kinase (14.4%) Aspartate kinase (14.4%) Aspartate kinase, monofunctional class (14.4%)" LEFDELSTVPFVEEDEEGNDLKCEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR007066 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 3 (9.3%)" SAFQTSGLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (15.4%) GO:0035999 (15.3%) GO:0032259 (11.3%)" "GO:0005829 (15.4%) GO:0005737 (0%)" "GO:0004372 (15.4%) GO:0030170 (15.4%) GO:0008168 (11.3%)" "glycine biosynthetic process from serine (15.4%) tetrahydrofolate interconversion (15.3%) methylation (11.3%)" "cytosol (15.4%) cytoplasm (0%)" "glycine hydroxymethyltransferase activity (15.4%) pyridoxal phosphate binding (15.4%) methyltransferase activity (11.3%)" "IPR019798 (14.3%) IPR039429 (14.3%) IPR049943 (14.3%)" "Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.3%) Serine hydroxymethyltransferase-like domain (14.3%) Serine hydroxymethyltransferase-like (14.3%)" FVWSEDNPCFFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (54.1%) GO:0016787 (45.9%) carbohydrate metabolic process (54.1%) hydrolase activity (45.9%) "IPR008313 (33.3%) IPR008928 (33.3%) IPR012341 (33.3%)" "Metal-independent alpha-mannosidase (33.3%) Six-hairpin glycosidase superfamily (33.3%) Six-hairpin glycosidase-like superfamily (33.3%)" MGPMHWGLLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR032533 (33.9%) IPR049208 (33.9%) IPR011004 (32.2%)" "Domain of unknown function DUF4954 (33.9%) Domain of unknown function DUF6819 (33.9%) Trimeric LpxA-like superfamily (32.2%)" LAEQLNAPLLAADATSVEDLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (34.1%) IPR014358 (34.1%) IPR036291 (31.8%)" "Short-chain dehydrogenase/reductase SDR (34.1%) Enoyl-[acyl-carrier-protein] reductase (NADH) (34.1%) NAD(P)-binding domain superfamily (31.8%)" ALGYEQDKDLLQLFDLAEEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.1%) IPR007644 (8.1%) IPR015712 (8.1%)" "RNA polymerase Rpb2, domain 2 (8.1%) RNA polymerase, beta subunit, protrusion (8.1%) DNA-directed RNA polymerase, subunit 2 (8.1%)" LFVLPVLDTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (30%) IPR017918 (30%) IPR011322 (20%)" "Nitrogen regulatory protein PII (30%) Nitrogen regulatory protein PII, conserved site (30%) Nitrogen regulatory PII-like, alpha/beta (20%)" NATLQDLTCDSDGK Pseudomonadati Bacteria Pseudomonadati 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.3%) GO:0008295 (19.3%) GO:0033388 (19.1%)" "GO:0008792 (19.3%) GO:0046872 (19.3%) GO:0004497 (3.8%)" "L-arginine catabolic process (19.3%) spermidine biosynthetic process (19.3%) putrescine biosynthetic process from arginine (19.1%)" "arginine decarboxylase activity (19.3%) metal ion binding (19.3%) monooxygenase activity (3.8%)" "IPR002985 (11.2%) IPR022644 (11.2%) IPR022653 (11.2%)" "Arginine decarboxylase (11.2%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.2%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.2%)" GEGLTFYGPEEALLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" LFESLGYR root "5.4.99.- (97.7%) 2.1.1.37 (0.8%) 2.7.11.1 (0.8%)" "Transferring other groups (97.7%) DNA (cytosine-5-)-methyltransferase (0.8%) non-specific serine/threonine protein kinase (0.8%)" "GO:0000455 (27.6%) GO:0015871 (1.1%) GO:0009307 (0.4%)" "GO:0042597 (1.1%) GO:0043190 (1.1%) GO:0016020 (0.9%)" "GO:0003723 (27.9%) GO:0120159 (27.6%) GO:0003677 (1.1%)" "enzyme-directed rRNA pseudouridine synthesis (27.6%) choline transport (1.1%) DNA restriction-modification system (0.4%)" "periplasmic space (1.1%) ATP-binding cassette (ABC) transporter complex (1.1%) membrane (0.9%)" "RNA binding (27.9%) rRNA pseudouridine synthase activity (27.6%) DNA binding (1.1%)" "IPR000748 (10.6%) IPR006145 (10.6%) IPR018496 (10.6%)" "Pseudouridine synthase, RsuA/RluB/E/F (10.6%) Pseudouridine synthase, RsuA/RluA-like (10.6%) Pseudouridine synthase, RsuA/RluB/E/F, conserved site (10.6%)" YSDLMLMR root 2.7.13.3 (100%) histidine kinase (100%) "GO:0006886 (3.2%) GO:0016192 (3.2%)" "GO:0009279 (83.9%) GO:0012505 (3.2%) GO:0030123 (3.2%)" GO:0000155 (3.2%) "intracellular protein transport (3.2%) vesicle-mediated transport (3.2%)" "cell outer membrane (83.9%) endomembrane system (3.2%) AP-3 adaptor complex (3.2%)" phosphorelay sensor kinase activity (3.2%) "IPR012944 (31.3%) IPR011990 (30.1%) IPR033985 (30.1%)" "RagB/SusD domain (31.3%) Tetratricopeptide-like helical domain superfamily (30.1%) SusD-like, N-terminal (30.1%)" AYAGNAADFEETQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (29.2%) GO:0030497 (4.2%)" "GO:0004316 (33.3%) GO:0051287 (33.3%)" "fatty acid biosynthetic process (29.2%) fatty acid elongation (4.2%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (33.3%) NAD binding (33.3%)" "IPR002347 (18.9%) IPR036291 (17%) IPR050259 (17%)" "Short-chain dehydrogenase/reductase SDR (18.9%) NAD(P)-binding domain superfamily (17%) Short-chain dehydrogenases/reductases (17%)" FNGAWGR root "3.2.1.3 (98.9%) 3.2.1.22 (1.1%)" "glucan 1,4-alpha-glucosidase (98.9%) alpha-galactosidase (1.1%)" "GO:0000272 (22.9%) GO:0015031 (0.5%) GO:0016052 (0.2%)" "GO:0000324 (23.1%) GO:0016020 (3.9%) GO:0005737 (0.5%)" "GO:0004339 (22.9%) GO:2001070 (21.9%) GO:0004553 (0.7%)" "polysaccharide catabolic process (22.9%) protein transport (0.5%) carbohydrate catabolic process (0.2%)" "fungal-type vacuole (23.1%) membrane (3.9%) cytoplasm (0.5%)" "glucan 1,4-alpha-glucosidase activity (22.9%) starch binding (21.9%) hydrolase activity, hydrolyzing O-glycosyl compounds (0.7%)" "IPR011613 (10.4%) IPR000165 (10.2%) IPR008928 (10.2%)" "GH15-like domain (10.4%) Glucoamylase (10.2%) Six-hairpin glycosidase superfamily (10.2%)" LTALPMEVPVCYQELAHCLDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000902 (24.9%) GO:0008360 (24.9%)" GO:0005737 (24.9%) "GO:0005524 (24.6%) GO:0016787 (0.8%)" "cell morphogenesis (24.9%) regulation of cell shape (24.9%)" cytoplasm (24.9%) "ATP binding (24.6%) hydrolase activity (0.8%)" "IPR004753 (31.5%) IPR043129 (31.5%) IPR056546 (31.5%)" "Cell shape determining protein MreB (31.5%) ATPase, nucleotide binding domain (31.5%) MreB/MamK-like (31.5%)" LQHAAEAGMDEFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025402 (100%) DNA mimic protein DMP19, C-terminal (100%) ANLVQNLNELGLELTPEQTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.5%) IPR002034 (14.5%) IPR013709 (14.5%)" "Pyruvate carboxyltransferase (14.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.5%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.5%)" FDGVGVSASNATLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" YLVDCYGQFLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (71.9%) "GO:0016787 (18.8%) GO:0016829 (9.4%)" carbohydrate metabolic process (71.9%) "hydrolase activity (18.8%) lyase activity (9.4%)" "IPR006047 (24.7%) IPR017853 (24.7%) IPR013783 (23.7%)" "Glycosyl hydrolase family 13, catalytic domain (24.7%) Glycoside hydrolase superfamily (24.7%) Immunoglobulin-like fold (23.7%)" VNLLGNGVVLAPDLFMGEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" QNLLLTGVK root 1.7.7.1 (100%) ferredoxin--nitrite reductase (100%) "GO:0043161 (8.6%) GO:0045721 (8.6%)" "GO:0005634 (8.6%) GO:0005737 (8.6%) GO:0034657 (8.6%)" "GO:0008270 (8.6%) GO:0020037 (8.6%) GO:0046872 (8.6%)" "proteasome-mediated ubiquitin-dependent protein catabolic process (8.6%) negative regulation of gluconeogenesis (8.6%)" "nucleus (8.6%) cytoplasm (8.6%) GID complex (8.6%)" "zinc ion binding (8.6%) heme binding (8.6%) metal ion binding (8.6%)" "IPR032149 (26.3%) IPR008160 (10.5%) IPR005117 (5.3%)" "Domain of unknown function DUF4988 (26.3%) Collagen triple helix repeat (10.5%) Nitrite/Sulfite reductase ferredoxin-like domain (5.3%)" SSFNRPNLYYEVR root "5.6.2.4 (93.8%) 3.6.4.12 (5.5%) 3.6.1.- (0.3%)" "DNA 3'-5' helicase (93.8%) DNA helicase (5.5%) In phosphorus-containing anhydrides (0.3%)" "GO:0006260 (5.7%) GO:0006310 (5.7%) GO:0006281 (5.5%)" "GO:0005737 (8.9%) GO:0030894 (5.5%) GO:0043590 (5.5%)" "GO:0005524 (9%) GO:0009378 (8.9%) GO:0043138 (8.9%)" "DNA replication (5.7%) DNA recombination (5.7%) DNA repair (5.5%)" "cytoplasm (8.9%) replisome (5.5%) bacterial nucleoid (5.5%)" "ATP binding (9%) four-way junction helicase activity (8.9%) 3'-5' DNA helicase activity (8.9%)" "IPR014001 (9.4%) IPR004589 (9.4%) IPR027417 (9.4%)" "Helicase superfamily 1/2, ATP-binding domain (9.4%) DNA helicase, ATP-dependent, RecQ type (9.4%) P-loop containing nucleoside triphosphate hydrolase (9.4%)" SVLFVAPMSPDGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" LVATLLENNQTPEGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.11 (100%) serine--tRNA ligase (100%) GO:0006434 (25%) GO:0005737 (25%) "GO:0004828 (25%) GO:0005524 (25%)" seryl-tRNA aminoacylation (25%) cytoplasm (25%) "serine-tRNA ligase activity (25%) ATP binding (25%)" "IPR002314 (14.6%) IPR002317 (14.6%) IPR006195 (14.6%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (14.6%) Serine-tRNA ligase, type1 (14.6%) Aminoacyl-tRNA synthetase, class II (14.6%)" LNANQGMGAFNAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (80%) 3.4.14.12 (20%)" "Acting on peptide bonds (peptidases) (80%) Xaa-Xaa-Pro tripeptidyl-peptidase (20%)" "GO:0006508 (48.1%) GO:0043171 (0.5%)" GO:0042597 (0.5%) "GO:0004252 (48.1%) GO:0004177 (1.6%) GO:0008239 (0.5%)" "proteolysis (48.1%) peptide catabolic process (0.5%)" periplasmic space (0.5%) "serine-type endopeptidase activity (48.1%) aminopeptidase activity (1.6%) dipeptidyl-peptidase activity (0.5%)" "IPR001375 (22.3%) IPR011659 (22.3%) IPR029058 (21.5%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (22.3%) WD40-like beta-propeller (22.3%) Alpha/Beta hydrolase fold (21.5%)" ENFLPWR root 2.7.13.3 (100%) histidine kinase (100%) GO:0006952 (2.4%) "GO:0005886 (21.4%) GO:0016020 (14.3%) GO:0005634 (2.4%)" "GO:0005524 (26.2%) GO:0004674 (19%) GO:0000155 (7.1%)" defense response (2.4%) "plasma membrane (21.4%) membrane (14.3%) nucleus (2.4%)" "ATP binding (26.2%) protein serine/threonine kinase activity (19%) phosphorelay sensor kinase activity (7.1%)" "IPR032675 (7.5%) IPR024788 (6.8%) IPR000719 (6%)" "Leucine-rich repeat domain superfamily (7.5%) Malectin-like domain (6.8%) Protein kinase domain (6%)" LLLASDRPPVELK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006270 (14.3%) GO:0006275 (14.3%)" "GO:0005737 (14.3%) GO:0005886 (14.3%)" "GO:0003688 (14.3%) GO:0005524 (14.3%) GO:0008289 (14.3%)" "DNA replication initiation (14.3%) regulation of DNA replication (14.3%)" "cytoplasm (14.3%) plasma membrane (14.3%)" "DNA replication origin binding (14.3%) ATP binding (14.3%) lipid binding (14.3%)" "IPR001957 (10.3%) IPR003593 (10.3%) IPR013159 (10.3%)" "Chromosomal replication control, initiator DnaA (10.3%) AAA+ ATPase domain (10.3%) Chromosomal replication initiator, DnaA C-terminal (10.3%)" LLSDPEASENDKYVALQFLR root 4.2.1.2 (100%) fumarate hydratase (100%) "GO:0006099 (20.2%) GO:0006106 (0.4%) GO:0006091 (0.2%)" GO:0016020 (0.2%) "GO:0046872 (21.6%) GO:0051539 (21.6%) GO:0004333 (20.7%)" "tricarboxylic acid cycle (20.2%) fumarate metabolic process (0.4%) generation of precursor metabolites and energy (0.2%)" membrane (0.2%) "metal ion binding (21.6%) 4 iron, 4 sulfur cluster binding (21.6%) fumarate hydratase activity (20.7%)" "IPR004646 (18.5%) IPR051208 (18.5%) IPR004647 (17.4%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.5%) Class-I Fumarase/Tartrate Dehydratase (18.5%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (17.4%)" LGLAAQSVGVEQEAYNEGLAYAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.3.8.1 (50%) 1.3.99.- (50%)" "short-chain acyl-CoA dehydrogenase (50%) With other acceptors (50%)" "GO:0050660 (50%) GO:0016627 (49.2%) GO:0016937 (0.8%)" "flavin adenine dinucleotide binding (50%) oxidoreductase activity, acting on the CH-CH group of donors (49.2%) short-chain fatty acyl-CoA dehydrogenase activity (0.8%)" "IPR006091 (10.2%) IPR009075 (10.2%) IPR013786 (10.2%)" "Acyl-CoA oxidase/dehydrogenase, middle domain (10.2%) Acyl-CoA dehydrogenase/oxidase, C-terminal (10.2%) Acyl-CoA dehydrogenase/oxidase, N-terminal (10.2%)" DLMPLLQANLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.1.108 (59.8%) 4.2.1.59 (40.2%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (59.8%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (40.2%)" "GO:0009245 (14.5%) GO:0006633 (12.9%)" "GO:0016020 (14.5%) GO:0005737 (14.3%)" "GO:0046872 (14.5%) GO:0103117 (14.5%) GO:0016836 (7.9%)" "lipid A biosynthetic process (14.5%) fatty acid biosynthetic process (12.9%)" "membrane (14.5%) cytoplasm (14.3%)" "metal ion binding (14.5%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.5%) hydro-lyase activity (7.9%)" "IPR004463 (14.8%) IPR013114 (14.8%) IPR011334 (14.3%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.8%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%) UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal (14.3%)" VLDRFEQQEDTFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" TVDGPSMKDWR root "1.2.1.- (63.7%) 1.2.1.12 (36.1%) 1.2.1.13 (0.1%)" "With NAD(+) or NADP(+) as acceptor (63.7%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (36.1%) glyceraldehyde-3-phosphate dehydrogenase (NADP(+)) (phosphorylating) (0.1%)" "GO:0006096 (17.5%) GO:0006006 (12.4%) GO:0072524 (0.1%)" "GO:0005829 (15.4%) GO:0032991 (1.2%) GO:0005737 (1%)" "GO:0004365 (18.3%) GO:0051287 (14.1%) GO:0050661 (12.5%)" "glycolytic process (17.5%) glucose metabolic process (12.4%) pyridine-containing compound metabolic process (0.1%)" "cytosol (15.4%) protein-containing complex (1.2%) cytoplasm (1%)" "glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (18.3%) NAD binding (14.1%) NADP binding (12.5%)" "IPR020829 (20.1%) IPR020831 (20.1%) IPR036291 (15.7%)" "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (20.1%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (20.1%) NAD(P)-binding domain superfamily (15.7%)" FPSTASLVLGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (20%)" GO:0005737 (20%) "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (20%)" cytoplasm (20%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" AADFVALMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0016485 (30.3%) GO:0006508 (4.5%)" GO:0016020 (30.3%) GO:0004252 (34.8%) "protein processing (30.3%) proteolysis (4.5%)" membrane (30.3%) serine-type endopeptidase activity (34.8%) "IPR000209 (17.1%) IPR023828 (17.1%) IPR036852 (16%)" "Peptidase S8/S53 domain (17.1%) Peptidase S8, subtilisin, Ser-active site (17.1%) Peptidase S8/S53 domain superfamily (16%)" NMLNTAQTDSFLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (31.6%) GO:0046677 (31.6%)" GO:0016020 (5.1%) GO:0008800 (31.6%) "beta-lactam antibiotic catabolic process (31.6%) response to antibiotic (31.6%)" membrane (5.1%) beta-lactamase activity (31.6%) "IPR000871 (25.5%) IPR045155 (25.5%) IPR012338 (24.5%)" "Beta-lactamase, class-A (25.5%) Beta-lactamase class A, catalytic domain (25.5%) Beta-lactamase/transpeptidase-like (24.5%)" VEGDENATVNTFAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.3.1.191 (96.6%) 2.3.1.- (3.4%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (96.6%) Transferring groups other than amino-acyl groups (3.4%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20.4%) IPR007691 (20.4%) IPR011004 (20.4%)" "Hexapeptide repeat (20.4%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20.4%) Trimeric LpxA-like superfamily (20.4%)" GYAPELLVFSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) VLFTQEWLALHPYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) ANMDFFLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" TYEHPVALR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (33.2%) "GO:0003921 (33.2%) GO:0005524 (33.2%) GO:0016740 (0.3%)" cytosol (33.2%) "GMP synthase activity (33.2%) ATP binding (33.2%) transferase activity (0.3%)" "IPR001674 (12.7%) IPR025777 (12.6%) IPR004739 (12.5%)" "GMP synthase, C-terminal (12.7%) GMP synthetase ATP pyrophosphatase domain (12.6%) GMP synthase, glutamine amidotransferase (12.5%)" LSVLEQDHFK Bacteria Bacteria "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (19.9%) IPR003593 (19.9%) IPR032781 (19.9%)" "ABC transporter-like, ATP-binding domain (19.9%) AAA+ ATPase domain (19.9%) ABC-transporter extension domain (19.9%)" DYYLNNDAATVALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25.2%) GO:0005886 (25.2%) "GO:0004222 (25.2%) GO:0046872 (24.5%)" protein processing (25.2%) plasma membrane (25.2%) "metalloendopeptidase activity (25.2%) metal ion binding (24.5%)" "IPR000718 (20.6%) IPR008753 (20.6%) IPR018497 (20.1%)" "Peptidase M13 (20.6%) Peptidase M13, N-terminal domain (20.6%) Peptidase M13, C-terminal domain (20.1%)" VLADDLADLLLLGNPANLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (57.1%) GO:0008959 (42.9%)" "acetyltransferase activity (57.1%) phosphate acetyltransferase activity (42.9%)" "IPR002505 (17%) IPR004614 (17%) IPR050500 (17%)" "Phosphate acetyl/butaryl transferase (17%) Phosphate acetyltransferase (17%) Phosphate Acetyltransferase/Butyryltransferase (17%)" NGLSLFFK root 2.7.13.3 (100%) histidine kinase (100%) "GO:0006457 (1.7%) GO:0050821 (1.7%) GO:0072344 (1.7%)" "GO:0009279 (54.2%) GO:0016020 (20.3%) GO:0005737 (3.4%)" "GO:0000155 (3.4%) GO:0000049 (1.7%) GO:0019901 (1.7%)" "protein folding (1.7%) protein stabilization (1.7%) rescue of stalled ribosome (1.7%)" "cell outer membrane (54.2%) membrane (20.3%) cytoplasm (3.4%)" "phosphorelay sensor kinase activity (3.4%) tRNA binding (1.7%) protein kinase binding (1.7%)" "IPR000531 (17.1%) IPR012910 (17.1%) IPR008969 (16%)" "TonB-dependent receptor-like, beta-barrel (17.1%) TonB-dependent receptor, plug domain (17.1%) Carboxypeptidase-like, regulatory domain superfamily (16%)" DFVVPSR root "6.1.1.12 (94.3%) 6.1.1.23 (2.8%) 3.6.5.- (2.5%)" "aspartate--tRNA ligase (94.3%) aspartate--tRNA(Asn) ligase (2.8%) Acting on GTP; involved in cellular and subcellular movement (2.5%)" "GO:0006422 (18.6%) GO:0000027 (0.6%) GO:0009409 (0.1%)" "GO:0005737 (18.3%) GO:0005829 (0.7%) GO:1990904 (0.7%)" "GO:0005524 (18.7%) GO:0004815 (18.6%) GO:0003676 (18.5%)" "aspartyl-tRNA aminoacylation (18.6%) ribosomal large subunit assembly (0.6%) response to cold (0.1%)" "cytoplasm (18.3%) cytosol (0.7%) ribonucleoprotein complex (0.7%)" "ATP binding (18.7%) aspartate-tRNA ligase activity (18.6%) nucleic acid binding (18.5%)" "IPR004364 (8.7%) IPR045864 (8.7%) IPR006195 (8.7%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (8.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (8.7%) Aminoacyl-tRNA synthetase, class II (8.7%)" EWECEVLSNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "7.2.1.1 (98.9%) 1.6.5.- (1.1%)" "NADH:ubiquinone reductase (Na(+)-transporting) (98.9%) With a quinone or similar compound as acceptor (1.1%)" GO:0006814 (16.7%) "GO:0005886 (16.5%) GO:0016020 (0.4%)" "GO:0016655 (16.7%) GO:0051537 (16.7%) GO:0046872 (16.5%)" sodium ion transport (16.7%) "plasma membrane (16.5%) membrane (0.4%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.7%) 2 iron, 2 sulfur cluster binding (16.7%) metal ion binding (16.5%)" "IPR008333 (10.2%) IPR010205 (10.2%) IPR017927 (10.2%)" "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.2%) Na(+)-translocating NADH-quinone reductase subunit F (10.2%) FAD-binding domain, ferredoxin reductase-type (10.2%)" QYGFWLVK Bacteria Bacteria 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (33.8%) "GO:0008446 (33.8%) GO:0070401 (32.4%)" 'de novo' GDP-L-fucose biosynthetic process (33.8%) "GDP-mannose 4,6-dehydratase activity (33.8%) NADP+ binding (32.4%)" "IPR006368 (33.5%) IPR016040 (33.5%) IPR036291 (33%)" "GDP-mannose 4,6-dehydratase (33.5%) NAD(P)-binding domain (33.5%) NAD(P)-binding domain superfamily (33%)" NLPFAYLLADGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR032533 (33.8%) IPR049208 (33.8%) IPR011004 (32.4%)" "Domain of unknown function DUF4954 (33.8%) Domain of unknown function DUF6819 (33.8%) Trimeric LpxA-like superfamily (32.4%)" GMPDFTEQESFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0009279 (50%) GO:1990351 (50%)" "cell outer membrane (50%) transporter complex (50%)" "IPR045659 (50%) IPR050218 (50%)" "LPS-assembly protein LptD, central domain (50%) Lipopolysaccharide Assembly Protein LptD (50%)" NFDLSGSHAYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (33.3%) IPR012334 (33.3%) IPR033427 (33.3%)" "Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%) Domain of unknown function DUF5123 (33.3%)" GDDLKDLLVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007121 (7.9%) IPR007641 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase, beta subunit, conserved site (7.9%) RNA polymerase Rpb2, domain 7 (7.9%)" MVAMQTATDNADELLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0042777 (19%) "GO:0045259 (19.6%) GO:0005886 (19%)" "GO:0046933 (19.6%) GO:0005524 (19%) GO:0016787 (3.8%)" proton motive force-driven plasma membrane ATP synthesis (19%) "proton-transporting ATP synthase complex (19.6%) plasma membrane (19%)" "proton-transporting ATP synthase activity, rotational mechanism (19.6%) ATP binding (19%) hydrolase activity (3.8%)" "IPR000131 (50.3%) IPR035968 (49.7%)" "ATP synthase, F1 complex, gamma subunit (50.3%) ATP synthase, F1 complex, gamma subunit superfamily (49.7%)" SLNNASQNNVSLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (34.5%) IPR050330 (34.5%) IPR036737 (31%)" "OmpA-like domain (34.5%) Bacterial Outer Membrane Structural/Functional (34.5%) OmpA-like domain superfamily (31%)" FVATGEVVSFDGFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.3%) "GO:0003677 (25.3%) GO:0003917 (25.3%) GO:0046872 (24.1%)" DNA topological change (25.3%) "DNA binding (25.3%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.3%) metal ion binding (24.1%)" "IPR000380 (7.6%) IPR003602 (7.6%) IPR013497 (7.6%)" "DNA topoisomerase, type IA (7.6%) DNA topoisomerase, type IA, DNA-binding domain (7.6%) DNA topoisomerase, type IA, central (7.6%)" EACNPYYDALPEVVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002869 (7.7%) IPR002880 (7.7%) IPR009014 (7.7%)" "Pyruvate-flavodoxin oxidoreductase, central domain (7.7%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.7%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (7.7%)" VGSGLLNPDESNCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.4.1.13 (97.8%) 1.4.-.- (2.2%)" "glutamate synthase (NADPH) (97.8%) Acting on the CH-NH2 group of donors (2.2%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" LDPVLGRDEELR root "3.4.21.92 (28.6%) 5.1.3.15 (21.4%) 3.6.1.3 (14.3%)" "endopeptidase Clp (28.6%) glucose-6-phosphate 1-epimerase (21.4%) Deleted entry (14.3%)" "GO:0034605 (18.4%) GO:0042026 (15.3%) GO:0006508 (2.7%)" "GO:0005737 (14.3%) GO:0005829 (3.9%) GO:0005759 (0.3%)" "GO:0005524 (18.5%) GO:0016887 (18.5%) GO:0042802 (3.9%)" "cellular response to heat (18.4%) protein refolding (15.3%) proteolysis (2.7%)" "cytoplasm (14.3%) cytosol (3.9%) mitochondrial matrix (0.3%)" "ATP binding (18.5%) ATP hydrolysis activity (18.5%) identical protein binding (3.9%)" "IPR050130 (8.6%) IPR027417 (8.6%) IPR003959 (8.6%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) P-loop containing nucleoside triphosphate hydrolase (8.6%) ATPase, AAA-type, core (8.6%)" KLVVVSSAPQLR root "2.4.2.14 (91.7%) 6.3.4.13 (5.6%) 6.3.3.1 (2.8%)" "amidophosphoribosyltransferase (91.7%) phosphoribosylamine--glycine ligase (5.6%) phosphoribosylformylglycinamidine cyclo-ligase (2.8%)" "GO:0006189 (1.4%) GO:0009113 (0.9%) GO:0046084 (0.5%)" GO:0005829 (0.5%) "GO:0016757 (77.3%) GO:0004044 (11.8%) GO:0016740 (3.8%)" "'de novo' IMP biosynthetic process (1.4%) purine nucleobase biosynthetic process (0.9%) adenine biosynthetic process (0.5%)" cytosol (0.5%) "glycosyltransferase activity (77.3%) amidophosphoribosyltransferase activity (11.8%) transferase activity (3.8%)" "IPR029057 (24.4%) IPR017932 (24.3%) IPR029055 (24.2%)" "Phosphoribosyltransferase-like (24.4%) Glutamine amidotransferase type 2 domain (24.3%) Nucleophile aminohydrolases, N-terminal (24.2%)" VGGDEAVSALNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR030890 (100%) Substrate import-associated zinc metallohydrolase lipoprotein (100%) CLTYAVSGGVDSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" NLPTLPLADSDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.21.107 (80%) 3.4.21.- (20%)" "peptidase Do (80%) Serine endopeptidases (20%)" GO:0006508 (49.1%) GO:0016020 (1.8%) GO:0004252 (49.1%) proteolysis (49.1%) membrane (1.8%) serine-type endopeptidase activity (49.1%) "IPR001478 (17.9%) IPR025926 (17.9%) IPR001940 (17.2%)" "PDZ domain (17.9%) PDZ-like domain (17.9%) Peptidase S1C (17.2%)" ALELLPEKDPTGLGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR033985 (33.8%) IPR012944 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) SusD-like, N-terminal (33.8%) RagB/SusD domain (32.4%)" NPGNFANAAPFLYSGDGSLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.1%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.1%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" MTPNDYTKEEMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (10.7%) GO:0009089 (10.7%) GO:0009097 (10.7%)" "GO:0046983 (11.8%) GO:0051287 (11.2%) GO:0004073 (10.7%)" "threonine biosynthetic process (10.7%) lysine biosynthetic process via diaminopimelate (10.7%) isoleucine biosynthetic process (10.7%)" "protein dimerization activity (11.8%) NAD binding (11.2%) aspartate-semialdehyde dehydrogenase activity (10.7%)" "IPR012280 (21.2%) IPR000534 (20.2%) IPR036291 (20.2%)" "Semialdehyde dehydrogenase, dimerisation domain (21.2%) Semialdehyde dehydrogenase, NAD-binding (20.2%) NAD(P)-binding domain superfamily (20.2%)" NVLGGVWVMPVSGMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.8%) IPR023614 (48.2%)" "Phosphate-selective porin O/P (51.8%) Porin domain superfamily (48.2%)" VLVFSGSK root "3.6.4.- (50%) 3.1.1.61 (25%) 3.5.1.44 (25%)" "Acting on ATP; involved in cellular and subcellular movement (50%) protein-glutamate methylesterase (25%) protein-glutamine glutaminase (25%)" "GO:0001525 (0.4%) GO:0006281 (0.4%) GO:0006325 (0.4%)" "GO:0005829 (17.5%) GO:0005576 (0.4%) GO:0005634 (0.4%)" "GO:0003676 (17.5%) GO:0003724 (17.5%) GO:0005524 (17.5%)" "angiogenesis (0.4%) DNA repair (0.4%) chromatin organization (0.4%)" "cytosol (17.5%) extracellular region (0.4%) nucleus (0.4%)" "nucleic acid binding (17.5%) RNA helicase activity (17.5%) ATP binding (17.5%)" "IPR001650 (13.4%) IPR011545 (13.4%) IPR014001 (13.4%)" "Helicase, C-terminal domain-like (13.4%) DEAD/DEAH-box helicase domain (13.4%) Helicase superfamily 1/2, ATP-binding domain (13.4%)" SSFQSPAYNAVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.37 (58.3%) 1.1.1.40 (41.7%)" "malate dehydrogenase (58.3%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (41.7%)" "GO:0006108 (34.2%) GO:0006089 (1.9%)" GO:0016020 (0.6%) "GO:0016615 (27.3%) GO:0016616 (27.3%) GO:0030060 (3.7%)" "malate metabolic process (34.2%) lactate metabolic process (1.9%)" membrane (0.6%) "malate dehydrogenase activity (27.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (27.3%) L-malate dehydrogenase (NAD+) activity (3.7%)" "IPR001236 (16.8%) IPR001557 (16.8%) IPR015955 (16.8%)" "Lactate/malate dehydrogenase, N-terminal (16.8%) L-lactate/malate dehydrogenase (16.8%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.8%)" NQFFSALLVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.1%) IPR028053 (17.1%) IPR028055 (17.1%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.1%) Membrane insertase YidC, N-terminal (17.1%) Membrane insertase YidC/Oxa/ALB, C-terminal (17.1%)" ASVQDALDNSFNVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" SDMTGALSSVNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "Carboxypeptidase-like, regulatory domain superfamily (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" AGGPEPENNPSLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006355 (31.6%) GO:0005829 (34.2%) GO:0003677 (34.2%) regulation of DNA-templated transcription (31.6%) cytosol (34.2%) DNA binding (34.2%) "IPR002876 (16.7%) IPR017856 (16.7%) IPR026564 (16.7%)" "Transcriptional regulator TACO1-like (16.7%) Integrase-like, N-terminal (16.7%) Transcriptional regulator TACO1-like, domain 3 (16.7%)" LLELGKEYGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" EADLHGYPLNLTELASHLQGTCYVTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044281 (33.3%) "GO:0016625 (33.3%) GO:0030976 (33.3%)" small molecule metabolic process (33.3%) "oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (33.3%) thiamine pyrophosphate binding (33.3%)" "IPR011766 (33.3%) IPR029061 (33.3%) IPR051457 (33.3%)" "Thiamine pyrophosphate enzyme, TPP-binding (33.3%) Thiamin diphosphate-binding fold (33.3%) 2-oxoacid:ferredoxin oxidoreductase (33.3%)" YLSMMQEVAQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20%) IPR001972 (20%) IPR018080 (20%)" "Band 7 domain (20%) Stomatin/HflK family (20%) Band 7/stomatin-like, conserved site (20%)" NNLYLGCMLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (60.2%) GO:0008959 (38.7%) GO:0016746 (1.1%)" "acetyltransferase activity (60.2%) phosphate acetyltransferase activity (38.7%) acyltransferase activity (1.1%)" "IPR002505 (16.9%) IPR050500 (16.9%) IPR004614 (16.7%)" "Phosphate acetyl/butaryl transferase (16.9%) Phosphate Acetyltransferase/Butyryltransferase (16.9%) Phosphate acetyltransferase (16.7%)" DGQDNSGEVLDSNDLERER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0000027 (9.8%) GO:0009409 (9.8%) GO:0010467 (9.8%)" "GO:0005829 (10.1%) GO:1990904 (10.1%)" "GO:0003924 (10.1%) GO:0005525 (10.1%) GO:0000049 (9.8%)" "ribosomal large subunit assembly (9.8%) response to cold (9.8%) gene expression (9.8%)" "cytosol (10.1%) ribonucleoprotein complex (10.1%)" "GTPase activity (10.1%) GTP binding (10.1%) tRNA binding (9.8%)" "IPR000795 (6.8%) IPR005225 (6.8%) IPR031157 (6.8%)" "Translational (tr)-type GTP-binding domain (6.8%) Small GTP-binding domain (6.8%) Tr-type G domain, conserved site (6.8%)" DCNVGDTLLGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.4%) IPR018223 (14.4%) IPR023434 (14.4%)" "Argininosuccinate synthase (14.4%) Argininosuccinate synthase, conserved site (14.4%) Argininosuccinate synthase, type 1 subfamily (14.4%)" HYAHVDCPGHADYVK root "3.6.5.3 (99.9%) 1.97.1.4 (0%) 2.7.11.1 (0%)" "protein-synthesizing GTPase (99.9%) [formate-C-acetyltransferase]-activating enzyme (0%) non-specific serine/threonine protein kinase (0%)" "GO:0070125 (1.9%) GO:0006414 (0%) GO:0009658 (0%)" "GO:0005829 (13.7%) GO:0032045 (7.7%) GO:0005739 (1.9%)" "GO:0003746 (17.3%) GO:0005525 (17.2%) GO:0003924 (17.2%)" "mitochondrial translational elongation (1.9%) translational elongation (0%) chloroplast organization (0%)" "cytosol (13.7%) guanyl-nucleotide exchange factor complex (7.7%) mitochondrion (1.9%)" "translation elongation factor activity (17.3%) GTP binding (17.2%) GTPase activity (17.2%)" "IPR000795 (9.2%) IPR050055 (9.1%) IPR027417 (9.1%)" "Translational (tr)-type GTP-binding domain (9.2%) Elongation factor Tu GTPase (9.1%) P-loop containing nucleoside triphosphate hydrolase (9.1%)" LQGMNLTFVTTAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" YCSLNLLGLR Pseudomonadati Bacteria Pseudomonadati 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (31.7%) GO:0008610 (2.4%)" GO:0016020 (31.7%) GO:0008780 (34.1%) "lipid A biosynthetic process (31.7%) lipid biosynthetic process (2.4%)" membrane (31.7%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.1%) "IPR010137 (20.6%) IPR011004 (20.6%) IPR029098 (20.6%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.6%) Trimeric LpxA-like superfamily (20.6%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.6%)" RTEVNHPASGLTSFTYDALGNVLTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.6%) GO:0005737 (48.6%)" GO:0016787 (2.7%) "extracellular region (48.6%) cytoplasm (48.6%)" hydrolase activity (2.7%) "IPR006530 (17.8%) IPR031325 (17.3%) IPR050708 (17.3%)" "YD repeat (17.8%) RHS repeat (17.3%) Type VI secretion system VgrG/RHS (17.3%)" LGNKGDECALDALK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.78 (100%) 6,7-dimethyl-8-ribityllumazine synthase (100%) GO:0009231 (24%) "GO:0005829 (24%) GO:0009349 (24%)" "GO:0000906 (24%) GO:0016874 (4.1%)" riboflavin biosynthetic process (24%) "cytosol (24%) riboflavin synthase complex (24%)" "6,7-dimethyl-8-ribityllumazine synthase activity (24%) ligase activity (4.1%)" "IPR002180 (33.3%) IPR034964 (33.3%) IPR036467 (33.3%)" "Lumazine/riboflavin synthase (33.3%) Lumazine synthase (33.3%) Lumazine/riboflavin synthase superfamily (33.3%)" FFYPNPLSSDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50.7%) "GO:0016787 (48%) GO:0016798 (1.3%)" carbohydrate metabolic process (50.7%) "hydrolase activity (48%) hydrolase activity, acting on glycosyl bonds (1.3%)" "IPR012878 (17.4%) IPR049046 (17.4%) IPR049049 (17.4%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.4%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17.4%)" FQPTAERPFVLGLPTGSSPQGMYANLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.5.99.6 (100%) glucosamine-6-phosphate deaminase (100%) "GO:0005975 (14.3%) GO:0006043 (14.3%) GO:0006046 (14.3%)" "GO:0005829 (13.6%) GO:0005737 (0.7%)" "GO:0004342 (14.3%) GO:0042802 (14.3%)" "carbohydrate metabolic process (14.3%) glucosamine catabolic process (14.3%) N-acetylglucosamine catabolic process (14.3%)" "cytosol (13.6%) cytoplasm (0.7%)" "glucosamine-6-phosphate deaminase activity (14.3%) identical protein binding (14.3%)" "IPR004547 (25.3%) IPR006148 (25.3%) IPR018321 (25.3%)" "Glucosamine-6-phosphate isomerase (25.3%) Glucosamine/galactosamine-6-phosphate isomerase (25.3%) Glucosamine-6-phosphate isomerase, conserved site (25.3%)" ALVEAGADALVLDTAHGHSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20.1%) GO:0006183 (20.1%)" "GO:0003938 (20.1%) GO:0046872 (20.1%) GO:0000166 (19.7%)" "GMP biosynthetic process (20.1%) GTP biosynthetic process (20.1%)" "IMP dehydrogenase activity (20.1%) metal ion binding (20.1%) nucleotide binding (19.7%)" "IPR000644 (16.9%) IPR001093 (16.9%) IPR005990 (16.9%)" "CBS domain (16.9%) IMP dehydrogenase/GMP reductase (16.9%) Inosine-5'-monophosphate dehydrogenase (16.9%)" EAGVEAFQDPAGNLVMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.3%) IPR002933 (33.3%) IPR011650 (33.3%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (33.3%) Peptidase M20, dimerisation domain (33.3%)" DADETGLLEGSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (33.8%) "GO:0004553 (33.8%) GO:0030246 (32.4%)" carbohydrate metabolic process (33.8%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.8%) carbohydrate binding (32.4%)" "IPR006710 (13%) IPR051795 (13%) IPR041542 (12.7%)" "Glycoside hydrolase, family 43 (13%) Glycosyl Hydrolase Family 43 (13%) Beta-xylosidase, C-terminal Concanavalin A-like domain (12.7%)" GLLHFAASK root 5.1.3.2 (100%) UDP-glucose 4-epimerase (100%) "GO:0006012 (33.2%) GO:0005996 (0.1%)" "GO:0005829 (33.3%) GO:1902495 (0.1%)" "GO:0003978 (33.3%) GO:0005216 (0.1%)" "galactose metabolic process (33.2%) monosaccharide metabolic process (0.1%)" "cytosol (33.3%) transmembrane transporter complex (0.1%)" "UDP-glucose 4-epimerase activity (33.3%) monoatomic ion channel activity (0.1%)" "IPR036291 (33.2%) IPR005886 (33%) IPR016040 (27.1%)" "NAD(P)-binding domain superfamily (33.2%) UDP-glucose 4-epimerase (33%) NAD(P)-binding domain (27.1%)" YLVVLVK root "3.5.1.99 (22.7%) 3.1.26.3 (18.2%) 2.7.13.3 (13.6%)" "fatty acid amide hydrolase (22.7%) ribonuclease III (18.2%) histidine kinase (13.6%)" "GO:0006397 (2.3%) GO:0009062 (2.3%) GO:0006364 (1.8%)" "GO:0016020 (8.3%) GO:0005737 (6%) GO:0005886 (5.5%)" "GO:0003725 (2.8%) GO:0005524 (2.8%) GO:0046872 (2.8%)" "mRNA processing (2.3%) fatty acid catabolic process (2.3%) rRNA processing (1.8%)" "membrane (8.3%) cytoplasm (6%) plasma membrane (5.5%)" "double-stranded RNA binding (2.8%) ATP binding (2.8%) metal ion binding (2.8%)" "IPR018683 (2.7%) IPR000999 (2%) IPR020556 (2%)" "Domain of unknown function DUF2169 (2.7%) Ribonuclease III domain (2%) Amidase, conserved site (2%)" ASYYDYYTGKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) IPR027417 (100%) P-loop containing nucleoside triphosphate hydrolase (100%) LSLALLPANHENTTLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (28.4%) IPR008969 (26.7%) IPR037066 (26.7%)" "TonB-dependent receptor, plug domain (28.4%) Carboxypeptidase-like, regulatory domain superfamily (26.7%) TonB-dependent receptor, plug domain superfamily (26.7%)" FAAFAFQK root 2.1.1.56 (100%) mRNA (guanine-N(7))-methyltransferase (100%) "GO:0005634 (28.6%) GO:0009279 (14.3%)" "GO:0003723 (28.6%) GO:0004482 (28.6%)" "nucleus (28.6%) cell outer membrane (14.3%)" "RNA binding (28.6%) mRNA 5'-cap (guanine-N7-)-methyltransferase activity (28.6%)" "IPR004971 (28.6%) IPR029063 (28.6%) IPR039753 (28.6%)" "mRNA (guanine-N(7))-methyltransferase domain (28.6%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (28.6%) mRNA cap guanine-N7 methyltransferase (28.6%)" GLTFSTPTELCKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0003824 (50%) carbohydrate metabolic process (50%) catalytic activity (50%) "IPR004300 (33.3%) IPR011330 (33.3%) IPR052046 (33.3%)" "Glycoside hydrolase family 57, N-terminal domain (33.3%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (33.3%) Glycosyl hydrolase family 57 (33.3%)" AAEAALHYHLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016226 (17%) "GO:0005524 (17%) GO:0051539 (17%) GO:0140663 (17%)" iron-sulfur cluster assembly (17%) "ATP binding (17%) 4 iron, 4 sulfur cluster binding (17%) ATP-dependent FeS chaperone activity (17%)" "IPR019591 (19.8%) IPR033756 (19.8%) IPR044304 (19.8%)" "Mrp/NBP35 ATP-binding protein (19.8%) Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 (19.8%) Iron-sulfur protein NUBPL-like (19.8%)" YVVSTLR root "2.7.1.92 (38.1%) 2.7.1.45 (19%) 1.17.7.4 (9.5%)" "5-dehydro-2-deoxygluconokinase (38.1%) 2-dehydro-3-deoxygluconokinase (19%) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase (9.5%)" "GO:0007155 (6.4%) GO:0030855 (3.3%) GO:0007156 (1.1%)" "GO:0005576 (6.1%) GO:0016020 (3.3%) GO:0009279 (1.7%)" "GO:0016301 (14.2%) GO:0005509 (7.1%) GO:0008201 (3%)" "cell adhesion (6.4%) epithelial cell differentiation (3.3%) homophilic cell-cell adhesion (1.1%)" "extracellular region (6.1%) membrane (3.3%) cell outer membrane (1.7%)" "kinase activity (14.2%) calcium ion binding (7.1%) heparin binding (3%)" "IPR011611 (8.1%) IPR029056 (8.1%) IPR052700 (8.1%)" "Carbohydrate kinase PfkB (8.1%) Ribokinase-like (8.1%) Carbohydrate kinase PfkB-like (8.1%)" VFSENFPLTDTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) "GO:0000428 (20%) GO:0016020 (0.4%)" "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (19.6%)" DNA-templated transcription (20%) "DNA-directed RNA polymerase complex (20%) membrane (0.4%)" "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (19.6%)" "IPR007642 (8.2%) IPR007644 (8.2%) IPR015712 (8%)" "RNA polymerase Rpb2, domain 2 (8.2%) RNA polymerase, beta subunit, protrusion (8.2%) DNA-directed RNA polymerase, subunit 2 (8%)" AWTAETPYLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.9%) IPR006102 (7.9%) IPR006103 (7.9%)" "Beta galactosidase small chain/ domain 5 (7.9%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.9%) Glycoside hydrolase family 2, catalytic domain (7.9%)" AQDEFNLVQAESNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" VAAGVGVTVDTLDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006183 (20.4%) GO:0006177 (19.9%)" "GO:0003938 (20.4%) GO:0046872 (19.9%) GO:0000166 (19.4%)" "GTP biosynthetic process (20.4%) GMP biosynthetic process (19.9%)" "IMP dehydrogenase activity (20.4%) metal ion binding (19.9%) nucleotide binding (19.4%)" "IPR000644 (17.1%) IPR001093 (17.1%) IPR005990 (17.1%)" "CBS domain (17.1%) IMP dehydrogenase/GMP reductase (17.1%) Inosine-5'-monophosphate dehydrogenase (17.1%)" WLLSSLNTLLK Pseudomonadati Bacteria Pseudomonadati 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.2%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.2%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" FHDMASQHFGNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (29.4%) GO:0009279 (41.2%) GO:0015344 (29.4%) siderophore transmembrane transport (29.4%) cell outer membrane (41.2%) siderophore uptake transmembrane transporter activity (29.4%) "IPR000531 (44.6%) IPR036942 (32.3%) IPR039426 (23.1%)" "TonB-dependent receptor-like, beta-barrel (44.6%) TonB-dependent receptor-like, beta-barrel domain superfamily (32.3%) TonB-dependent receptor-like (23.1%)" GLLDALLSGDLDKAPTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.1%) GO:0005829 (17.1%) "GO:0004612 (17.1%) GO:0005524 (17.1%) GO:0046872 (17.1%)" gluconeogenesis (17.1%) cytosol (17.1%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.1%) ATP binding (17.1%) metal ion binding (17.1%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" EQPDAAVSVDTYRPTLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.15 (100%) dihydropteroate synthase (100%) "GO:0046654 (20%) GO:0046656 (20%)" GO:0005829 (20%) "GO:0004156 (20%) GO:0046872 (20%)" "tetrahydrofolate biosynthetic process (20%) folic acid biosynthetic process (20%)" cytosol (20%) "dihydropteroate synthase activity (20%) metal ion binding (20%)" "IPR000489 (25.2%) IPR006390 (25.2%) IPR045031 (25.2%)" "Pterin-binding domain (25.2%) Dihydropteroate synthase domain (25.2%) Dihydropteroate synthase-like (25.2%)" NLLNSPGNFTASK Pseudomonadati Bacteria Pseudomonadati "2.7.1.17 (71.4%) 2.7.1.- (28.6%)" "xylulokinase (71.4%) Phosphotransferases with an alcohol group as acceptor (28.6%)" GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (20.9%) IPR050406 (20.9%) IPR000577 (20.3%)" "Carbohydrate kinase FGGY, N-terminal (20.9%) FGGY Carbohydrate Kinase (20.9%) Carbohydrate kinase, FGGY (20.3%)" SPLLDELLNYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006261 (16.7%) GO:0006302 (16.7%)" "GO:0003677 (16.7%) GO:0003887 (16.7%) GO:0008408 (16.7%)" "DNA-templated DNA replication (16.7%) double-strand break repair (16.7%)" "DNA binding (16.7%) DNA-directed DNA polymerase activity (16.7%) 3'-5' exonuclease activity (16.7%)" "IPR001098 (7.8%) IPR002298 (7.8%) IPR002421 (7.8%)" "DNA-directed DNA polymerase, family A, palm domain (7.8%) DNA polymerase A (7.8%) 5'-3' exonuclease (7.8%)" GKDVLVLGGGDTGSDCLGTAHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.4.1.- (33.3%) 1.4.1.13 (33.3%) 1.4.1.14 (33.3%)" "With NAD(+) or NADP(+) as acceptor (33.3%) glutamate synthase (NADPH) (33.3%) glutamate synthase (NADH) (33.3%)" GO:0006537 (32.5%) "GO:0051536 (33.1%) GO:0016639 (32.5%) GO:0004355 (0.6%)" glutamate biosynthetic process (32.5%) "iron-sulfur cluster binding (33.1%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (32.5%) glutamate synthase (NADPH) activity (0.6%)" "IPR009051 (16.2%) IPR023753 (16.2%) IPR028261 (16.2%)" "Alpha-helical ferredoxin (16.2%) FAD/NAD(P)-binding domain (16.2%) Dihydroprymidine dehydrogenase domain II (16.2%)" GELLNQEYVSGNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.0 (100%) Unknown (100%) GO:0045727 (16.7%) GO:0005886 (16.7%) "GO:0003746 (16.7%) GO:0003924 (16.7%) GO:0005525 (16.7%)" positive regulation of translation (16.7%) plasma membrane (16.7%) "translation elongation factor activity (16.7%) GTPase activity (16.7%) GTP binding (16.7%)" "IPR000640 (9.7%) IPR000795 (9.7%) IPR004161 (9.7%)" "Elongation factor EFG, domain V-like (9.7%) Translational (tr)-type GTP-binding domain (9.7%) Translation elongation factor EFTu-like, domain 2 (9.7%)" NVWTVAK root "1.8.1.2 (33.3%) 2.3.1.- (33.3%) 3.4.16.- (33.3%)" "assimilatory sulfite reductase (NADPH) (33.3%) Transferring groups other than amino-acyl groups (33.3%) Serine-type carboxypeptidases (33.3%)" "GO:0006412 (16.8%) GO:0000027 (15.8%) GO:0000103 (0%)" "GO:0005840 (16.8%) GO:1990904 (16.8%) GO:0005576 (0%)" "GO:0003735 (16.8%) GO:0019843 (16.8%) GO:0016810 (0.1%)" "translation (16.8%) ribosomal large subunit assembly (15.8%) sulfate assimilation (0%)" "ribosome (16.8%) ribonucleoprotein complex (16.8%) extracellular region (0%)" "structural constituent of ribosome (16.8%) rRNA binding (16.8%) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (0.1%)" "IPR005813 (33%) IPR035566 (33%) IPR049946 (32.9%)" "Large ribosomal subunit protein bL20 (33%) Ribosomal protein bL20, C-terminal (33%) Large ribosomal subunit protein bL20, conserved site (32.9%)" YLASLPVVFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016798 (49%) GO:0030246 (49%) GO:0016787 (2%)" "hydrolase activity, acting on glycosyl bonds (49%) carbohydrate binding (49%) hydrolase activity (2%)" "IPR013785 (12.9%) IPR019563 (12.9%) IPR029483 (12.9%)" "Aldolase-type TIM barrel (12.9%) Glycosyl-hydrolase 97, catalytic domain (12.9%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (12.9%)" FFDALLK root "6.1.1.9 (44%) 2.7.13.3 (17.4%) 3.2.1.21 (5.5%)" "valine--tRNA ligase (44%) histidine kinase (17.4%) beta-glucosidase (5.5%)" "GO:0000447 (5.6%) GO:0007264 (4.8%) GO:0006438 (2.7%)" "GO:0005886 (7%) GO:0005737 (6.7%) GO:0005730 (5.7%)" "GO:0005085 (5.3%) GO:0031267 (4.6%) GO:0005524 (4.2%)" "endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (5.6%) small GTPase-mediated signal transduction (4.8%) valyl-tRNA aminoacylation (2.7%)" "plasma membrane (7%) cytoplasm (6.7%) nucleolus (5.7%)" "guanyl-nucleotide exchange factor activity (5.3%) small GTPase binding (4.6%) ATP binding (4.2%)" "IPR018034 (4%) IPR024626 (3.5%) IPR016024 (3.1%)" "KRR1 interacting protein 1 (4%) Kri1-like, C-terminal (3.5%) Armadillo-type fold (3.1%)" LAMTNLVFPVAPYENVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR013189 (15.6%) IPR013320 (14.6%) IPR001362 (14.1%)" "Glycosyl hydrolase family 32, C-terminal (15.6%) Concanavalin A-like lectin/glucanase domain superfamily (14.6%) Glycoside hydrolase, family 32 (14.1%)" NGSAMLFVSSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.3.99.1 (76.9%) 1.3.5.1 (15.4%) 1.3.5.4 (7.7%)" "Deleted entry (76.9%) succinate dehydrogenase (15.4%) Transferred entry: 1.3.5.1 (7.7%)" "GO:0009060 (24.1%) GO:0022904 (24.1%)" "GO:0009055 (24.1%) GO:0051537 (24.1%) GO:0016491 (2.7%)" "aerobic respiration (24.1%) respiratory electron transport chain (24.1%)" "electron transfer activity (24.1%) 2 iron, 2 sulfur cluster binding (24.1%) oxidoreductase activity (2.7%)" "IPR009051 (13.8%) IPR017896 (13.8%) IPR006058 (13.6%)" "Alpha-helical ferredoxin (13.8%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (13.8%) 2Fe-2S ferredoxin, iron-sulphur binding site (13.6%)" QNLGQMANDAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (42.3%) IPR011990 (38.5%) IPR050498 (19.2%)" "Tetratricopeptide repeat (42.3%) Tetratricopeptide-like helical domain superfamily (38.5%) Photosystem I assembly protein Ycf3 (19.2%)" AYWSDGAQVLAPHDTGLLEEVNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.9%) IPR016066 (14.9%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.9%) Alpha-D-phosphohexomutase, conserved site (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" LVNLFKPLYENPELLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) "GO:0006261 (16.7%) GO:0006302 (16.7%)" "GO:0003677 (16.7%) GO:0003887 (16.7%) GO:0008408 (16.7%)" "DNA-templated DNA replication (16.7%) double-strand break repair (16.7%)" "DNA binding (16.7%) DNA-directed DNA polymerase activity (16.7%) 3'-5' exonuclease activity (16.7%)" "IPR001098 (7.9%) IPR002298 (7.9%) IPR002421 (7.9%)" "DNA-directed DNA polymerase, family A, palm domain (7.9%) DNA polymerase A (7.9%) 5'-3' exonuclease (7.9%)" AYASVAYSNREPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" YVGLTPAELQMAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) NLKDSELAYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" EVTWMPAYGPEQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.2.7.1 (53.8%) 1.2.7.3 (42.3%) 1.2.7.7 (3.8%)" "pyruvate synthase (53.8%) 2-oxoglutarate synthase (42.3%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (3.8%)" "GO:0016903 (84.6%) GO:0019164 (7%) GO:0047553 (5.5%)" "oxidoreductase activity, acting on the aldehyde or oxo group of donors (84.6%) pyruvate synthase activity (7%) 2-oxoglutarate synthase activity (5.5%)" "IPR019752 (33.1%) IPR052554 (33.1%) IPR002869 (32.9%)" "Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (33.1%) 2-oxoglutarate synthase subunit KorC (33.1%) Pyruvate-flavodoxin oxidoreductase, central domain (32.9%)" YLATVNVR root GO:0006826 (6.1%) GO:0009279 (93.9%) iron ion transport (6.1%) cell outer membrane (93.9%) "IPR008969 (12.4%) IPR012910 (12.4%) IPR023996 (12.4%)" "Carboxypeptidase-like, regulatory domain superfamily (12.4%) TonB-dependent receptor, plug domain (12.4%) TonB-dependent outer membrane protein, SusC/RagA (12.4%)" DMLAALQALR Bacteria Bacteria 3.5.4.2 (100%) adenine deaminase (100%) "GO:0034605 (19.5%) GO:0042026 (19.5%) GO:0006146 (1.1%)" GO:0005737 (19.5%) "GO:0005524 (19.5%) GO:0016887 (19.5%) GO:0000034 (1.1%)" "cellular response to heat (19.5%) protein refolding (19.5%) adenine catabolic process (1.1%)" cytoplasm (19.5%) "ATP binding (19.5%) ATP hydrolysis activity (19.5%) adenine deaminase activity (1.1%)" "IPR003593 (8.3%) IPR003959 (8.3%) IPR004176 (8.3%)" "AAA+ ATPase domain (8.3%) ATPase, AAA-type, core (8.3%) Clp, repeat (R) N-terminal domain (8.3%)" LPVSVLCSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.2%) IPR002772 (9.2%) IPR011658 (9.2%)" "Glycoside hydrolase, family 3, N-terminal (9.2%) Glycoside hydrolase family 3 C-terminal domain (9.2%) PA14 domain (9.2%)" TAPLNSDLQGYYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) TWMEGLEYLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" QDLLGLGYKNDLVNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.3%) IPR009027 (14.3%) IPR020069 (14.3%)" "Large ribosomal subunit protein bL9 (14.3%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.3%) Large ribosomal subunit protein bL9, C-terminal (14.3%)" VTEDGYYTLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (51.5%) GO:0016787 (48.5%) carbohydrate metabolic process (51.5%) hydrolase activity (48.5%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" LVDQLNESNQYLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.97.1.12 (100%) photosystem I (100%) GO:0016020 (97.4%) GO:0016491 (2.6%) membrane (97.4%) oxidoreductase activity (2.6%) "IPR006665 (33.5%) IPR050330 (33.5%) IPR036737 (32.9%)" "OmpA-like domain (33.5%) Bacterial Outer Membrane Structural/Functional (33.5%) OmpA-like domain superfamily (32.9%)" LEGETNDYFAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (13.7%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (13.7%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" QVASQLYGSTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR012505 (50%) IPR053154 (50%)" "YbbR-like (50%) Cyclic di-AMP regulator (50%)" DLYGYDAAK root "GO:0000272 (30.6%) GO:0006080 (30.6%) GO:0030245 (2%)" "GO:0005576 (2%) GO:0009986 (2%)" "GO:0016985 (30.6%) GO:0008422 (2%)" "polysaccharide catabolic process (30.6%) substituted mannan metabolic process (30.6%) cellulose catabolic process (2%)" "extracellular region (2%) cell surface (2%)" "mannan endo-1,4-beta-mannosidase activity (30.6%) beta-glucosidase activity (2%)" "IPR001547 (25.4%) IPR022790 (25.4%) IPR000805 (23.8%)" "Glycoside hydrolase, family 5 (25.4%) Glycosyl hydrolase family 26 domain (25.4%) Glycoside hydrolase family 26 (23.8%)" VQLTYDLPSTLFQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.5%) IPR023996 (34.5%) IPR037066 (31%)" "TonB-dependent receptor, plug domain (34.5%) TonB-dependent outer membrane protein, SusC/RagA (34.5%) TonB-dependent receptor, plug domain superfamily (31%)" YGLTGATVLAHNPSYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.2%) GO:0005829 (17.2%) "GO:0004612 (17.2%) GO:0005524 (17.2%) GO:0046872 (17.2%)" gluconeogenesis (17.2%) cytosol (17.2%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.2%) ATP binding (17.2%) metal ion binding (17.2%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" LTGLAQGVRDGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" NNSAVQLLMDPNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" LEASSGLSEDELNR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005524 (33.9%) GO:0140662 (33.9%) GO:0051082 (32.2%)" "ATP binding (33.9%) ATP-dependent protein folding chaperone (33.9%) unfolded protein binding (32.2%)" "IPR013126 (16.9%) IPR029047 (16.9%) IPR029048 (16.9%)" "Heat shock protein 70 family (16.9%) Heat shock protein 70kD, peptide-binding domain superfamily (16.9%) Heat shock protein 70kD, C-terminal domain superfamily (16.9%)" YVMALMNGAR Pseudomonadati Bacteria Pseudomonadati "1.3.99.- (50.9%) 1.3.8.1 (36.8%) 1.3.8.- (8.8%)" "With other acceptors (50.9%) short-chain acyl-CoA dehydrogenase (36.8%) With a flavin as acceptor (8.8%)" "GO:0050660 (49.7%) GO:0003995 (34.1%) GO:0016627 (13.6%)" "flavin adenine dinucleotide binding (49.7%) acyl-CoA dehydrogenase activity (34.1%) oxidoreductase activity, acting on the CH-CH group of donors (13.6%)" "IPR052166 (9.4%) IPR036250 (9.4%) IPR009100 (9.3%)" "Diverse substrate specificity acyl-CoA dehydrogenase (9.4%) Acyl-CoA dehydrogenase-like, C-terminal (9.4%) Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily (9.3%)" LPVLLVANK root "3.6.5.- (75%) 3.6.5.2 (23.1%) 2.7.4.25 (1.9%)" "Acting on GTP; involved in cellular and subcellular movement (75%) small monomeric GTPase (23.1%) (d)CMP kinase (1.9%)" "GO:0042254 (12.8%) GO:0007005 (3%) GO:0002098 (2.5%)" "GO:0005741 (3.3%) GO:0005737 (2.6%) GO:0005886 (1.8%)" "GO:0005525 (25.3%) GO:0043022 (11.9%) GO:0003924 (8.6%)" "ribosome biogenesis (12.8%) mitochondrion organization (3%) tRNA wobble uridine modification (2.5%)" "mitochondrial outer membrane (3.3%) cytoplasm (2.6%) plasma membrane (1.8%)" "GTP binding (25.3%) ribosome binding (11.9%) GTPase activity (8.6%)" "IPR027417 (16.1%) IPR005225 (11.5%) IPR006073 (10.3%)" "P-loop containing nucleoside triphosphate hydrolase (16.1%) Small GTP-binding domain (11.5%) GTP binding domain (10.3%)" YFSDATLKAEVEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SLETLNLVSNNFNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR001611 (21.2%) IPR024361 (21.2%) IPR052595 (21.2%)" "Leucine-rich repeat (21.2%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (21.2%) Leucine-rich repeat-containing protein 69/Receptor-like (21.2%)" SLPYDEFKDNDTLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "7.1.1.- (94.7%) 1.6.5.9 (5.3%)" "Hydron translocation or charge separation linked to oxidoreductase reactions (94.7%) NADH:ubiquinone reductase (non-electrogenic) (5.3%)" "GO:0009060 (11.1%) GO:0015990 (11.1%)" "GO:0005886 (11.1%) GO:0045271 (11.1%)" "GO:0005506 (11.1%) GO:0008137 (11.1%) GO:0048038 (11.1%)" "aerobic respiration (11.1%) electron transport coupled proton transport (11.1%)" "plasma membrane (11.1%) respiratory chain complex I (11.1%)" "iron ion binding (11.1%) NADH dehydrogenase (ubiquinone) activity (11.1%) quinone binding (11.1%)" "IPR006137 (50%) IPR006138 (50%)" "NADH:ubiquinone oxidoreductase-like, 20kDa subunit (50%) NADH-ubiquinone oxidoreductase, 20 Kd subunit (50%)" YMQSENFEDTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009298 (27.1%) GO:0005976 (25%)" "GO:0004475 (27.1%) GO:0000166 (20.8%)" "GDP-mannose biosynthetic process (27.1%) polysaccharide metabolic process (25%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (27.1%) nucleotide binding (20.8%)" "IPR005835 (18.8%) IPR051161 (18.8%) IPR001538 (17.4%)" "Nucleotidyl transferase domain (18.8%) Mannose-6-phosphate isomerase type 2 (18.8%) Mannose-6-phosphate isomerase, type II, C-terminal (17.4%)" KPELDATLVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.5%) GO:0022627 (20.5%) "GO:0003735 (20.5%) GO:0019843 (20.5%) GO:0003729 (18.2%)" translation (20.5%) cytosolic small ribosomal subunit (20.5%) "structural constituent of ribosome (20.5%) rRNA binding (20.5%) mRNA binding (18.2%)" "IPR001351 (11%) IPR004044 (11%) IPR004087 (11%)" "Small ribosomal subunit protein uS3, C-terminal (11%) K Homology domain, type 2 (11%) K Homology domain (11%)" SFDNVSPTVTVYDVLDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.3%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.3%) "IPR006530 (16.3%) IPR050708 (16.3%) IPR031325 (15.9%)" "YD repeat (16.3%) Type VI secretion system VgrG/RHS (16.3%) RHS repeat (15.9%)" DLYAWLK root "6.1.1.20 (48.9%) 2.7.7.15 (33.6%) 2.7.7.19 (6.6%)" "phenylalanine--tRNA ligase (48.9%) choline-phosphate cytidylyltransferase (33.6%) polynucleotide adenylyltransferase (6.6%)" "GO:0006432 (10%) GO:0031123 (1.4%) GO:0043634 (1.4%)" "GO:0009328 (10%) GO:0016020 (1.7%) GO:0005730 (1.4%)" "GO:0005524 (10.5%) GO:0000049 (10.1%) GO:0000287 (10%)" "phenylalanyl-tRNA aminoacylation (10%) RNA 3'-end processing (1.4%) polyadenylation-dependent ncRNA catabolic process (1.4%)" "phenylalanine-tRNA ligase complex (10%) membrane (1.7%) nucleolus (1.4%)" "ATP binding (10.5%) tRNA binding (10.1%) magnesium ion binding (10%)" "IPR002547 (5.3%) IPR004532 (5.3%) IPR005121 (5.3%)" "tRNA-binding domain (5.3%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (5.3%) Ferrodoxin-fold anticodon-binding domain (5.3%)" TSVLLGLLK root "2.7.1.11 (60%) 2.3.1.108 (40%)" "6-phosphofructokinase (60%) alpha-tubulin N-acetyltransferase (40%)" "GO:0006002 (4.3%) GO:0030388 (4.3%) GO:0061621 (4.3%)" "GO:0005945 (4.3%) GO:0005874 (2.9%) GO:0009328 (2.9%)" "GO:0016829 (31.4%) GO:0003872 (4.3%) GO:0005524 (4.3%)" "fructose 6-phosphate metabolic process (4.3%) fructose 1,6-bisphosphate metabolic process (4.3%) canonical glycolysis (4.3%)" "6-phosphofructokinase complex (4.3%) microtubule (2.9%) phenylalanine-tRNA ligase complex (2.9%)" "lyase activity (31.4%) 6-phosphofructokinase activity (4.3%) ATP binding (4.3%)" "IPR003961 (22.1%) IPR033803 (22.1%) IPR013783 (20.1%)" "Fibronectin type III (22.1%) Golvesin/Xly, CBD-like (22.1%) Immunoglobulin-like fold (20.1%)" LVPYSPGCGSVTELNNAQAAGCDVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (64.7%) GO:0008675 (17.6%) GO:0008700 (17.6%)" "lyase activity (64.7%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (17.6%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (17.6%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" AFFDENGLGYAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.6%) GO:0006164 (0.6%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.6%) GO:0046872 (19.6%)" "'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.6%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.6%) metal ion binding (19.6%)" "IPR010918 (11.5%) IPR010073 (11.1%) IPR036676 (11.1%)" "PurM-like, C-terminal domain (11.5%) Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain superfamily (11.1%)" SADFGQLLNAAGALKDVSLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) GADFVVLR root "1.1.1.85 (85.7%) 2.1.3.2 (12.2%) 2.8.1.6 (2%)" "3-isopropylmalate dehydrogenase (85.7%) aspartate carbamoyltransferase (12.2%) biotin synthase (2%)" "GO:0009098 (16.3%) GO:0006207 (0.9%) GO:0006520 (0.9%)" "GO:0005829 (17.2%) GO:0009705 (0.4%)" "GO:0000287 (16.3%) GO:0003862 (16.3%) GO:0051287 (16.3%)" "L-leucine biosynthetic process (16.3%) 'de novo' pyrimidine nucleobase biosynthetic process (0.9%) amino acid metabolic process (0.9%)" "cytosol (17.2%) plant-type vacuole membrane (0.4%)" "magnesium ion binding (16.3%) 3-isopropylmalate dehydrogenase activity (16.3%) NAD binding (16.3%)" "IPR004429 (18%) IPR019818 (18%) IPR024084 (18%)" "Isopropylmalate dehydrogenase (18%) Isocitrate/isopropylmalate dehydrogenase, conserved site (18%) Isopropylmalate dehydrogenase-like domain (18%)" TYLSAAWDLNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.7%) IPR033985 (33.7%) IPR011990 (32.6%)" "RagB/SusD domain (33.7%) SusD-like, N-terminal (33.7%) Tetratricopeptide-like helical domain superfamily (32.6%)" TTLNAWTPTNTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GELFNCQTTVENEKDMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006004 (31.8%) GO:0005996 (1.5%)" GO:0005737 (33.3%) "GO:0008736 (31.8%) GO:0016861 (1.5%)" "fucose metabolic process (31.8%) monosaccharide metabolic process (1.5%)" cytoplasm (33.3%) "L-fucose isomerase activity (31.8%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1.5%)" "IPR009015 (50%) IPR015888 (50%)" "L-fucose isomerase, N-terminal/central domain superfamily (50%) L-fucose isomerase, C-terminal (50%)" EFTLQALDKGSDDVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" NLTFTLAR root "1.5.5.2 (50%) 7.4.2.10 (50%)" "proline dehydrogenase (50%) ABC-type glutathione transporter (50%)" "GO:0006898 (2.9%) GO:0010133 (2.9%) GO:0015833 (2.9%)" "GO:0016020 (8.8%) GO:0005739 (2.9%) GO:0005886 (2.9%)" "GO:0016747 (38.2%) GO:0005509 (8.8%) GO:0004657 (2.9%)" "receptor-mediated endocytosis (2.9%) L-proline catabolic process to L-glutamate (2.9%) peptide transport (2.9%)" "membrane (8.8%) mitochondrion (2.9%) plasma membrane (2.9%)" "acyltransferase activity, transferring groups other than amino-acyl groups (38.2%) calcium ion binding (8.8%) proline dehydrogenase activity (2.9%)" "IPR016181 (26.7%) IPR000182 (21.7%) IPR000033 (1.7%)" "Acyl-CoA N-acyltransferase (26.7%) GNAT domain (21.7%) LDLR class B repeat (1.7%)" YRYEPEMNMYVER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.1%) GO:0005737 (49.1%)" GO:0016787 (1.8%) "extracellular region (49.1%) cytoplasm (49.1%)" hydrolase activity (1.8%) "IPR006530 (15.8%) IPR050708 (15.4%) IPR031325 (14.9%)" "YD repeat (15.8%) Type VI secretion system VgrG/RHS (15.4%) RHS repeat (14.9%)" LQQAYQDGQQELQKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (50%) IPR024930 (50%)" "Chaperone protein Skp (50%) Skp domain superfamily (50%)" YCQAYFSYDSK Bacteria Bacteria "1.2.7.1 (85.2%) 1.2.7.- (11.1%) 1.2.1.51 (3.7%)" "pyruvate synthase (85.2%) With an iron-sulfur protein as acceptor (11.1%) pyruvate dehydrogenase (NADP(+)) (3.7%)" "GO:0006979 (15.1%) GO:0022900 (15%) GO:0044281 (11.2%)" "GO:0005506 (15%) GO:0051539 (15%) GO:0030976 (13.5%)" "response to oxidative stress (15.1%) electron transport chain (15%) small molecule metabolic process (11.2%)" "iron ion binding (15%) 4 iron, 4 sulfur cluster binding (15%) thiamine pyrophosphate binding (13.5%)" "IPR019752 (7.9%) IPR050722 (7.9%) IPR011895 (7.8%)" "Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (7.9%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.9%) Pyruvate-flavodoxin oxidoreductase (7.8%)" AENMTVEQMQEEFPAHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.8%) GO:0005829 (32.8%) "GO:0008926 (32.8%) GO:0009026 (1.6%)" mannitol catabolic process (32.8%) cytosol (32.8%) "mannitol-1-phosphate 5-dehydrogenase activity (32.8%) tagaturonate reductase activity (1.6%)" "IPR013118 (22%) IPR013131 (22%) IPR008927 (18.7%)" "Mannitol dehydrogenase, C-terminal (22%) Mannitol dehydrogenase, N-terminal (22%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.7%)" YAYEEADHASR Bacteria Bacteria 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (26%) GO:0016491 (16%)" "iron ion binding (50%) peroxidase activity (26%) oxidoreductase activity (16%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" NLPMWQLPLELHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.5 (100%) chorismate mutase (100%) GO:0046417 (48.8%) "GO:0004106 (48.8%) GO:0003849 (2.3%)" chorismate metabolic process (48.8%) "chorismate mutase activity (48.8%) 3-deoxy-7-phosphoheptulonate synthase activity (2.3%)" "IPR002701 (17.1%) IPR006218 (17.1%) IPR052899 (17.1%)" "Chorismate mutase II, prokaryotic-type (17.1%) DAHP synthetase I/KDSA (17.1%) Class-I DAHP synthase (17.1%)" FGDSFDEAQFR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (13.4%) GO:0015966 (11.3%) GO:0044281 (1.8%)" "GO:0005737 (13.4%) GO:0070062 (11.3%) GO:1990742 (11.3%)" "GO:0004820 (13.4%) GO:0005524 (13%) GO:0004081 (11.3%)" "glycyl-tRNA aminoacylation (13.4%) diadenosine tetraphosphate biosynthetic process (11.3%) small molecule metabolic process (1.8%)" "cytoplasm (13.4%) extracellular exosome (11.3%) microvesicle (11.3%)" "glycine-tRNA ligase activity (13.4%) ATP binding (13%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (11.3%)" "IPR027031 (11.4%) IPR002314 (11.1%) IPR002315 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.4%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Glycyl-tRNA synthetase (11.1%)" SDMELLTR root "2.4.2.14 (78.5%) 2.1.3.2 (20.7%) 4.2.1.10 (0.8%)" "amidophosphoribosyltransferase (78.5%) aspartate carbamoyltransferase (20.7%) 3-dehydroquinate dehydratase (0.8%)" "GO:0009113 (14.8%) GO:0006189 (9.1%) GO:0006164 (5.7%)" "GO:0005829 (3.8%) GO:0005643 (0.2%) GO:0005737 (0.2%)" "GO:0004044 (14.8%) GO:0046872 (14.4%) GO:0051536 (14.4%)" "purine nucleobase biosynthetic process (14.8%) 'de novo' IMP biosynthetic process (9.1%) purine nucleotide biosynthetic process (5.7%)" "cytosol (3.8%) nuclear pore (0.2%) cytoplasm (0.2%)" "amidophosphoribosyltransferase activity (14.8%) metal ion binding (14.4%) iron-sulfur cluster binding (14.4%)" "IPR000836 (15.6%) IPR017932 (15.5%) IPR029057 (15.3%)" "Phosphoribosyltransferase domain (15.6%) Glutamine amidotransferase type 2 domain (15.5%) Phosphoribosyltransferase-like (15.3%)" YLLLSSSQPGGQAANLQGVWNDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (49.2%) GO:0004560 (50.8%) carbohydrate metabolic process (49.2%) alpha-L-fucosidase activity (50.8%) "IPR027414 (16.9%) IPR049053 (16.9%) IPR054363 (16.9%)" "Glycosyl hydrolase family 95, N-terminal domain (16.9%) Alpha fucosidase A-like, C-terminal domain (16.9%) Glycosyl hydrolase family 95, catalytic domain (16.9%)" VVVGYWK root "5.3.1.4 (98.5%) 2.4.1.14 (0.8%) 3.4.16.- (0.8%)" "L-arabinose isomerase (98.5%) sucrose-phosphate synthase (0.8%) Serine-type carboxypeptidases (0.8%)" "GO:0019569 (24.5%) GO:0005986 (0.2%) GO:0006508 (0.2%)" "GO:0005829 (24.5%) GO:0016020 (0.6%) GO:0005886 (0.2%)" "GO:0008733 (24.5%) GO:0030145 (23.9%) GO:0046872 (0.6%)" "L-arabinose catabolic process to D-xylulose 5-phosphate (24.5%) sucrose biosynthetic process (0.2%) proteolysis (0.2%)" "cytosol (24.5%) membrane (0.6%) plasma membrane (0.2%)" "L-arabinose isomerase activity (24.5%) manganese ion binding (23.9%) metal ion binding (0.6%)" "IPR003762 (13.9%) IPR024664 (13.9%) IPR055389 (13.9%)" "L-arabinose isomerase (13.9%) L-arabinose isomerase, C-terminal (13.9%) L-arabinose isomerase, N-terminal domain (13.9%)" LAMDLLHEGMLDEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10.1%) IPR002192 (10.1%) IPR008279 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate phosphate dikinase, AMP/ATP-binding (10.1%) PEP-utilising enzyme, mobile domain (10.1%)" TDNFLPSADEAAKPESLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.4 (100%) leucine--tRNA ligase (100%) GO:0006429 (20%) "GO:0005829 (20%) GO:0005739 (0.6%)" "GO:0004823 (20%) GO:0005524 (20%) GO:0002161 (19.4%)" leucyl-tRNA aminoacylation (20%) "cytosol (20%) mitochondrion (0.6%)" "leucine-tRNA ligase activity (20%) ATP binding (20%) aminoacyl-tRNA deacylase activity (19.4%)" "IPR002300 (12.8%) IPR002302 (12.8%) IPR013155 (12.8%)" "Aminoacyl-tRNA synthetase, class Ia (12.8%) Leucine-tRNA ligase (12.8%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.8%)" FNPFSMK root 3.6.5.2 (100%) small monomeric GTPase (100%) "GO:0071709 (34.1%) GO:0015833 (3.4%) GO:0042884 (3.4%)" "GO:0009279 (34.1%) GO:0030288 (3.4%) GO:0043190 (3.4%)" "GO:1904680 (3.4%) GO:0043565 (2.3%) GO:0003924 (1.1%)" "membrane assembly (34.1%) peptide transport (3.4%) microcin transport (3.4%)" "cell outer membrane (34.1%) outer membrane-bounded periplasmic space (3.4%) ATP-binding cassette (ABC) transporter complex (3.4%)" "peptide transmembrane transporter activity (3.4%) sequence-specific DNA binding (2.3%) GTPase activity (1.1%)" "IPR010827 (14.7%) IPR034746 (14.7%) IPR023707 (14.2%)" "POTRA domain, BamA/TamA-like (14.7%) POTRA domain (14.7%) Outer membrane protein assembly factor BamA (14.2%)" EWEFLPDNLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025178 (50%) IPR057436 (50%)" "Lnb, N-terminal periplasmic domain (50%) Lnb-like, transmembrane domain (50%)" EVNFLEGQGLLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" GFSGSHVADYNDATGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (36.4%) "GO:0004556 (31.8%) GO:0043169 (31.8%)" carbohydrate metabolic process (36.4%) "alpha-amylase activity (31.8%) cation binding (31.8%)" "IPR006047 (36.4%) IPR006046 (31.8%) IPR017853 (31.8%)" "Glycosyl hydrolase family 13, catalytic domain (36.4%) Alpha amylase (31.8%) Glycoside hydrolase superfamily (31.8%)" ATTQDQMYQYHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.7%) IPR008969 (48.3%)" "Family of unknown function DUF5686 (51.7%) Carboxypeptidase-like, regulatory domain superfamily (48.3%)" LAALMQVPVK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.2.1.1 (98.2%) 2.2.1.- (1.8%)" "transketolase (98.2%) Transketolases and transaldolases (1.8%)" GO:0006098 (24.9%) GO:0005829 (24.9%) "GO:0004802 (24.9%) GO:0046872 (24.9%) GO:0003863 (0.4%)" pentose-phosphate shunt (24.9%) cytosol (24.9%) "transketolase activity (24.9%) metal ion binding (24.9%) branched-chain 2-oxo acid dehydrogenase activity (0.4%)" "IPR005475 (12.8%) IPR020826 (12.8%) IPR029061 (12.8%)" "Transketolase-like, pyrimidine-binding domain (12.8%) Transketolase binding site (12.8%) Thiamin diphosphate-binding fold (12.8%)" MEFTAQQLAQFVQGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.191 (100%) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (100%) GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20.2%) IPR007691 (20.2%) IPR011004 (20.2%)" "Hexapeptide repeat (20.2%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20.2%) Trimeric LpxA-like superfamily (20.2%)" VDNLQYLDPSMLESMEVLK Pseudomonadati Bacteria Pseudomonadati GO:0044718 (5.1%) GO:0009279 (89.7%) GO:0015344 (5.1%) siderophore transmembrane transport (5.1%) cell outer membrane (89.7%) siderophore uptake transmembrane transporter activity (5.1%) "IPR012910 (13.9%) IPR037066 (13.9%) IPR039426 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent receptor, plug domain superfamily (13.9%) TonB-dependent receptor-like (13.9%)" LMEFLGNVVPFVSEMPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (25.1%) "GO:0003746 (25.1%) GO:0005525 (25.1%) GO:0003924 (24.8%)" ribosome disassembly (25.1%) "translation elongation factor activity (25.1%) GTP binding (25.1%) GTPase activity (24.8%)" "IPR041095 (7.8%) IPR000795 (7.7%) IPR005517 (7.7%)" "Elongation Factor G, domain II (7.8%) Translational (tr)-type GTP-binding domain (7.7%) Translation elongation factor EFG/EF2, domain IV (7.7%)" YLATYTFR root "GO:0006886 (7.4%) GO:0016197 (7.4%) GO:0042144 (7.4%)" "GO:0009279 (48.1%) GO:0005765 (7.4%) GO:0005768 (7.4%)" GO:0003779 (7.4%) "intracellular protein transport (7.4%) endosomal transport (7.4%) vacuole fusion, non-autophagic (7.4%)" "cell outer membrane (48.1%) lysosomal membrane (7.4%) endosome (7.4%)" actin binding (7.4%) "IPR036942 (13.3%) IPR039426 (13.3%) IPR008969 (12.8%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (13.3%) TonB-dependent receptor-like (13.3%) Carboxypeptidase-like, regulatory domain superfamily (12.8%)" YDSYDALMFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (4.2%) GO:0009279 (91.7%) GO:0015344 (4.2%) siderophore transmembrane transport (4.2%) cell outer membrane (91.7%) siderophore uptake transmembrane transporter activity (4.2%) "IPR012910 (15.9%) IPR023997 (15.9%) IPR039426 (15.9%)" "TonB-dependent receptor, plug domain (15.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.9%) TonB-dependent receptor-like (15.9%)" LNLPFHLAEDPLHSVAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000902 (24.7%) GO:0008360 (24.7%)" GO:0005737 (25.1%) "GO:0005524 (24.2%) GO:0016787 (1.3%)" "cell morphogenesis (24.7%) regulation of cell shape (24.7%)" cytoplasm (25.1%) "ATP binding (24.2%) hydrolase activity (1.3%)" "IPR043129 (31.8%) IPR056546 (31.8%) IPR004753 (31.3%)" "ATPase, nucleotide binding domain (31.8%) MreB/MamK-like (31.8%) Cell shape determining protein MreB (31.3%)" EEWYTSEEAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (15%) GO:0009279 (85%) iron ion transport (15%) cell outer membrane (85%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" GLELDLDKGLDAVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (25%) "GO:0046872 (25%) GO:0051539 (25%) GO:0004333 (24.1%)" tricarboxylic acid cycle (25%) "metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%) fumarate hydratase activity (24.1%)" "IPR004646 (18.6%) IPR004647 (18.6%) IPR051208 (18.6%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.6%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.6%) Class-I Fumarase/Tartrate Dehydratase (18.6%)" LCFDVFGADR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR021474 (100%) Protein of unknown function DUF3127 (100%) EAREEGFEELAAK Bacteria Bacteria "GO:0005506 (50%) GO:0016491 (42.9%) GO:0016692 (7.1%)" "iron ion binding (50%) oxidoreductase activity (42.9%) NADH peroxidase activity (7.1%)" "IPR003251 (14.3%) IPR009040 (14.3%) IPR009078 (14.3%)" "Rubrerythrin, diiron-binding domain (14.3%) Ferritin-like diiron domain (14.3%) Ferritin-like superfamily (14.3%)" ATQFGVPVSFKPTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0045493 (50%) GO:0016798 (50%) xylan catabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR025112 (50%) IPR038653 (50%)" "Putative carbohydrate metabolism domain (50%) Putative carbohydrate metabolism domain superfamily (50%)" NVVLLDDMVDTAGTLTK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (10.9%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (10.9%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (17.9%) IPR005946 (17.9%) IPR029057 (17.9%)" "Phosphoribosyltransferase domain (17.9%) Ribose-phosphate pyrophosphokinase (17.9%) Phosphoribosyltransferase-like (17.9%)" MELYVRPEVAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.7%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.7%)" "IPR004733 (20%) IPR010918 (20%) IPR016188 (20%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, C-terminal domain (20%) PurM-like, N-terminal domain (20%)" MLGEGFSVENCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.1 (100%) alkaline phosphatase (100%) GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (35%) IPR026263 (33%) IPR017850 (32%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (35%) Alkaline phosphatase, prokaryotic (33%) Alkaline-phosphatase-like, core domain superfamily (32%)" GAMVYQSPMSLLDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (95%) GO:0015344 (5%) cell outer membrane (95%) siderophore uptake transmembrane transporter activity (5%) "IPR036942 (95%) IPR039426 (5%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (95%) TonB-dependent receptor-like (5%)" LAEGATMLR root 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (24.5%) GO:0008615 (24.5%) GO:0042823 (24.5%)" "GO:0036381 (22.9%) GO:0016843 (1.6%) GO:0030170 (0.7%)" "amino acid metabolic process (24.5%) pyridoxine biosynthetic process (24.5%) pyridoxal phosphate biosynthetic process (24.5%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (22.9%) amine-lyase activity (1.6%) pyridoxal phosphate binding (0.7%)" "IPR001852 (24.1%) IPR011060 (24.1%) IPR013785 (24.1%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (24.1%) Ribulose-phosphate binding barrel (24.1%) Aldolase-type TIM barrel (24.1%)" ANLDEALVLHPMER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.1.23 (100%) dUTP diphosphatase (100%) "GO:0006226 (25%) GO:0046081 (25%)" "GO:0000287 (25%) GO:0004170 (25%)" "dUMP biosynthetic process (25%) dUTP catabolic process (25%)" "magnesium ion binding (25%) dUTP diphosphatase activity (25%)" "IPR008181 (25%) IPR029054 (25%) IPR033704 (25%)" "Deoxyuridine triphosphate nucleotidohydrolase (25%) dUTPase-like (25%) dUTPase, trimeric (25%)" GTTSQPSLSQLLDLTDNSDPLNLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR041700 (87.1%) IPR008969 (12.9%)" "Outer membrane protein beta-barrel domain 3 (87.1%) Carboxypeptidase-like, regulatory domain superfamily (12.9%)" SVMAFLENHDTDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.2.1.1 (37.5%) 3.2.1.135 (25%) 3.2.1.54 (25%)" "alpha-amylase (37.5%) neopullulanase (25%) cyclomaltodextrinase (25%)" GO:0005975 (49.7%) "GO:0016798 (45.9%) GO:0004556 (1.6%) GO:0031216 (1.1%)" carbohydrate metabolic process (49.7%) "hydrolase activity, acting on glycosyl bonds (45.9%) alpha-amylase activity (1.6%) neopullulanase activity (1.1%)" "IPR006047 (14.6%) IPR015171 (14.6%) IPR019492 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (14.6%) Cyclomaltodextrinase, N-terminal (14.6%) Cyclo-malto-dextrinase, C-terminal (14.6%)" GLTPMLNSATLSGDNLGVDDKNLYPLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LLADVGLVGFPNAGK root "3.6.5.- (99.9%) 3.6.1.15 (0.1%)" "Acting on GTP; involved in cellular and subcellular movement (99.9%) nucleoside-triphosphate phosphatase (0.1%)" "GO:0042254 (16.9%) GO:0042048 (0.1%) GO:1902093 (0.1%)" "GO:0005737 (10.3%) GO:0005739 (6.5%) GO:0005730 (5.3%)" "GO:0005525 (17.5%) GO:0003924 (17.3%) GO:0000287 (16%)" "ribosome biogenesis (16.9%) olfactory behavior (0.1%) positive regulation of flagellated sperm motility (0.1%)" "cytoplasm (10.3%) mitochondrion (6.5%) nucleolus (5.3%)" "GTP binding (17.5%) GTPase activity (17.3%) magnesium ion binding (16%)" "IPR006073 (12.9%) IPR031167 (12.9%) IPR027417 (12.9%)" "GTP binding domain (12.9%) OBG-type guanine nucleotide-binding (G) domain (12.9%) P-loop containing nucleoside triphosphate hydrolase (12.9%)" LLNKVEVP root "3.6.3.- (90.6%) 4.4.1.5 (6.3%) 3.6.5.0 (3.1%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (90.6%) lactoylglutathione lyase (6.3%) Unknown (3.1%)" "GO:0006412 (0.2%) GO:0045727 (0.2%) GO:0080188 (0.2%)" "GO:0016020 (0.4%) GO:0005634 (0.2%) GO:0005743 (0.2%)" "GO:0005524 (48.2%) GO:0016887 (48%) GO:0004462 (0.4%)" "translation (0.2%) positive regulation of translation (0.2%) gene silencing by siRNA-directed DNA methylation (0.2%)" "membrane (0.4%) nucleus (0.2%) mitochondrial inner membrane (0.2%)" "ATP binding (48.2%) ATP hydrolysis activity (48%) lactoylglutathione lyase activity (0.4%)" "IPR027417 (23.9%) IPR041628 (23.8%) IPR011703 (23.7%)" "P-loop containing nucleoside triphosphate hydrolase (23.9%) ChlI/MoxR, AAA lid domain (23.8%) ATPase, AAA-3 (23.7%)" NLYVVDGFCGANK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.3%) GO:0005829 (17.3%) "GO:0004612 (17.3%) GO:0005524 (17.3%) GO:0046872 (17.3%)" gluconeogenesis (17.3%) cytosol (17.3%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.3%) ATP binding (17.3%) metal ion binding (17.3%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" LDANNLTEASLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" LFQMVGNDEATAQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" KAVDASLDANVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) GO:0009098 (19.9%) GO:0005829 (19.9%) "GO:0000287 (19.9%) GO:0003862 (19.9%) GO:0051287 (19.9%)" L-leucine biosynthetic process (19.9%) cytosol (19.9%) "magnesium ion binding (19.9%) 3-isopropylmalate dehydrogenase activity (19.9%) NAD binding (19.9%)" "IPR004429 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isopropylmalate dehydrogenase (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" LSGSTSWGLLTPTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" ALGFQDKDLLVSTDLGEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (25.2%) GO:0016020 (25.2%) "GO:0004222 (25.2%) GO:0046872 (24.3%)" proteolysis (25.2%) membrane (25.2%) "metalloendopeptidase activity (25.2%) metal ion binding (24.3%)" "IPR004387 (25.2%) IPR008915 (25.2%) IPR041489 (25.2%)" "Peptidase M50, putative membrane-associated zinc metallopeptidase (25.2%) Peptidase M50 (25.2%) PDZ domain 6 (25.2%)" YDLSPVLK root "2.7.11.1 (75%) 2.3.2.30 (25%)" "non-specific serine/threonine protein kinase (75%) L-ornithine N(alpha)-acyltransferase (25%)" "GO:0006629 (1.5%) GO:0015031 (1.5%) GO:0030639 (1.5%)" "GO:0009279 (30.3%) GO:0005737 (4.5%) GO:0016020 (4.5%)" "GO:0003677 (13.6%) GO:0016787 (9.1%) GO:0004065 (6.1%)" "lipid metabolic process (1.5%) protein transport (1.5%) polyketide biosynthetic process (1.5%)" "cell outer membrane (30.3%) cytoplasm (4.5%) membrane (4.5%)" "DNA binding (13.6%) hydrolase activity (9.1%) arylsulfatase activity (6.1%)" "IPR012910 (8.4%) IPR023996 (8.4%) IPR023997 (8.4%)" "TonB-dependent receptor, plug domain (8.4%) TonB-dependent outer membrane protein, SusC/RagA (8.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (8.4%)" LSDDKAQMDMLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (18.5%) GO:0012505 (18.5%) GO:0045259 (18.5%)" "GO:0046933 (18.5%) GO:0046961 (18.5%) GO:0016787 (7.4%)" "plasma membrane (18.5%) endomembrane system (18.5%) proton-transporting ATP synthase complex (18.5%)" "proton-transporting ATP synthase activity, rotational mechanism (18.5%) proton-transporting ATPase activity, rotational mechanism (18.5%) hydrolase activity (7.4%)" "IPR002146 (25.6%) IPR005864 (25.6%) IPR050059 (25.6%)" "ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast (25.6%) ATP synthase, F0 complex, subunit b, bacterial (25.6%) ATP synthase B chain (25.6%)" LLQWYNLLAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "IPR041218 (26.2%) IPR049280 (26.2%) IPR049281 (23.8%)" "Domain of unknown function DUF5606 (26.2%) Domain of unknown function DUF6852 (26.2%) BVU_3817-like, C-terminal domain superfamily (23.8%)" AEKYEENDLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.1%) GO:0043335 (16.1%) GO:0051083 (16.1%)" GO:0005737 (3.4%) "GO:0003755 (16.1%) GO:0043022 (16.1%) GO:0044183 (16.1%)" "protein transport (16.1%) protein unfolding (16.1%) 'de novo' cotranslational protein folding (16.1%)" cytoplasm (3.4%) "peptidyl-prolyl cis-trans isomerase activity (16.1%) ribosome binding (16.1%) protein folding chaperone (16.1%)" "IPR005215 (20%) IPR008881 (20%) IPR027304 (18.6%)" "Trigger factor (20%) Trigger factor, ribosome-binding, bacterial (20%) Trigger factor/SurA domain superfamily (18.6%)" GNLGVTTENLFPVLKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (1.2%) "GO:0005524 (24%) GO:0016887 (24%) GO:0051082 (24%)" cytoplasm (1.2%) "ATP binding (24%) ATP hydrolysis activity (24%) unfolded protein binding (24%)" "IPR001404 (17.7%) IPR020575 (17.7%) IPR036890 (17.5%)" "Heat shock protein Hsp90 family (17.7%) Heat shock protein Hsp90, N-terminal (17.7%) Histidine kinase/HSP90-like ATPase superfamily (17.5%)" LQELNSDYEAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005737 (50%) GO:0016881 (50%) cytoplasm (50%) acid-amino acid ligase activity (50%) "IPR004993 (30.3%) IPR055377 (30.3%) IPR055378 (30.3%)" "GH3 family (30.3%) GH3, middle domain (30.3%) GH3, C-terminal domain (30.3%)" KTDLFVLR root "5.1.3.3 (65.7%) 2.1.3.2 (28.6%) 5.1.3.- (2.9%)" "aldose 1-epimerase (65.7%) aspartate carbamoyltransferase (28.6%) Acting on carbohydrates and derivatives (2.9%)" "GO:0006006 (11.8%) GO:0033499 (11.8%) GO:0006207 (4.4%)" "GO:0005737 (12.7%) GO:0005829 (4.4%) GO:0005634 (0.5%)" "GO:0004034 (11.8%) GO:0030246 (11.8%) GO:0004070 (4.4%)" "glucose metabolic process (11.8%) galactose catabolic process via UDP-galactose, Leloir pathway (11.8%) 'de novo' pyrimidine nucleobase biosynthetic process (4.4%)" "cytoplasm (12.7%) cytosol (4.4%) nucleus (0.5%)" "aldose 1-epimerase activity (11.8%) carbohydrate binding (11.8%) aspartate carbamoyltransferase activity (4.4%)" "IPR008183 (12.1%) IPR011013 (12.1%) IPR014718 (12.1%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (12.1%) Galactose mutarotase-like domain superfamily (12.1%) Glycoside hydrolase-type carbohydrate-binding (12.1%)" LGGLQADLDPNFVQNVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (50%) 1.6.5.9 (50%)" "Transferred entry: 1.6.5.9 (50%) NADH:ubiquinone reductase (non-electrogenic) (50%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" LSVVAPNLGLSLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (20.5%) GO:0006221 (20.5%)" GO:0009347 (20.5%) "GO:0046872 (20.5%) GO:0016740 (17.9%)" "'de novo' pyrimidine nucleobase biosynthetic process (20.5%) pyrimidine nucleotide biosynthetic process (20.5%)" aspartate carbamoyltransferase complex (20.5%) "metal ion binding (20.5%) transferase activity (17.9%)" "IPR002801 (21.1%) IPR020542 (21.1%) IPR020545 (21.1%)" "Aspartate transcarbamylase regulatory subunit (21.1%) Aspartate carbamoyltransferase regulatory subunit, C-terminal (21.1%) Aspartate carbamoyltransferase regulatory subunit, N-terminal (21.1%)" LHATVGADYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.9%) IPR012910 (11.9%) IPR023996 (11.9%)" "TonB-dependent receptor-like, beta-barrel (11.9%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" SLNLPVNVR Bacteria Bacteria "GO:0003677 (33.3%) GO:0016757 (33.3%) GO:0016779 (33.3%)" "DNA binding (33.3%) glycosyltransferase activity (33.3%) nucleotidyltransferase activity (33.3%)" "IPR027385 (52.2%) IPR011250 (44.9%) IPR029494 (2.9%)" "Outer membrane protein, beta-barrel domain (52.2%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (44.9%) ssDNA thymidine ADP-ribosyltransferase, DarT (2.9%)" VEMDDQLAGETGEAFGTLYGDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR032283 (36.4%) IPR038081 (33.8%) IPR032299 (29.9%)" "Domain of unknown function DUF4984 (36.4%) CalX-like domain superfamily (33.8%) Protein of unknown function DUF4843 (29.9%)" YGVNTEFLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" AVVANLLKPEGLNYGQLPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025393 (52.5%) IPR029044 (47.5%)" "Domain of unknown function DUF4301 (52.5%) Nucleotide-diphospho-sugar transferases (47.5%)" NGQGYDHNYVLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20%) GO:0033499 (20%)" GO:0005737 (20%) "GO:0004034 (20%) GO:0030246 (20%)" "glucose metabolic process (20%) galactose catabolic process via UDP-galactose, Leloir pathway (20%)" cytoplasm (20%) "aldose 1-epimerase activity (20%) carbohydrate binding (20%)" "IPR008183 (20%) IPR011013 (20%) IPR014718 (20%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (20%) Galactose mutarotase-like domain superfamily (20%) Glycoside hydrolase-type carbohydrate-binding (20%)" YLYDDMFVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) LGNSEDYDKAFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0047617 (100%) fatty acyl-CoA hydrolase activity (100%) "IPR006684 (34%) IPR050563 (34%) IPR029069 (32.1%)" "Acyl-CoA thioester hydrolase YbgC/YbaW family (34%) 4-hydroxybenzoyl-CoA thioesterase (34%) HotDog domain superfamily (32.1%)" GLTLNSAHLEYETAKR Bacteria Bacteria 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (15%) GO:0032045 (12%)" "GO:0000287 (15%) GO:0003746 (15%) GO:0003924 (15%)" "cytosol (15%) guanyl-nucleotide exchange factor complex (12%)" "magnesium ion binding (15%) translation elongation factor activity (15%) GTPase activity (15%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" LGFEDGERLESPMLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" LVDEPELLTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) LLELEHDSLYNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006353 (19.3%) GO:0031564 (19.3%)" GO:0005829 (19.3%) "GO:0003700 (19.3%) GO:0003723 (19.3%) GO:0003746 (2.4%)" "DNA-templated transcription termination (19.3%) transcription antitermination (19.3%)" cytosol (19.3%) "DNA-binding transcription factor activity (19.3%) RNA binding (19.3%) translation elongation factor activity (2.4%)" "IPR003029 (11.1%) IPR010213 (11.1%) IPR013735 (11.1%)" "S1 domain (11.1%) Transcription factor NusA (11.1%) Transcription factor NusA, N-terminal (11.1%)" GLTEPTPTFSACFGQAFLELHPTK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.6%) GO:0005829 (17.6%) "GO:0004612 (17.6%) GO:0005524 (17.6%) GO:0046872 (17%)" gluconeogenesis (17.6%) cytosol (17.6%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.6%) ATP binding (17.6%) metal ion binding (17%)" "IPR001272 (25.3%) IPR013035 (25.3%) IPR015994 (24.8%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.3%) Phosphoenolpyruvate carboxykinase, C-terminal (25.3%) Phosphoenolpyruvate carboxykinase (ATP), conserved site (24.8%)" LSDHGLEEFYDEPYTDSQLETLFAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.8%) IPR032466 (47.2%)" "Uronate isomerase (52.8%) Metal-dependent hydrolase (47.2%)" DLQNALNECQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.5%) "GO:0009279 (26.4%) GO:0046930 (24.5%)" GO:0015288 (24.5%) monoatomic ion transport (24.5%) "cell outer membrane (26.4%) pore complex (24.5%)" porin activity (24.5%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" SELYKPAYDLNHQALEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (13.9%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (13.9%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (7.9%) IPR012162 (7.9%) IPR015847 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) Polyribonucleotide nucleotidyltransferase (7.9%) Exoribonuclease, phosphorolytic domain 2 (7.9%)" DSWTDGHLNPDYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.45 (100%) glucosylceramidase (100%) GO:0006680 (33.3%) GO:0016020 (33.3%) GO:0004348 (33.3%) glucosylceramide catabolic process (33.3%) membrane (33.3%) glucosylceramidase activity (33.3%) "IPR001139 (20.3%) IPR033452 (20.3%) IPR033453 (20.3%)" "Glycoside hydrolase family 30 (20.3%) Glycosyl hydrolase family 30, beta sandwich domain (20.3%) Glycosyl hydrolase family 30, TIM-barrel domain (20.3%)" VSWVDDKGNVQTNMGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.4%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.4%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" AASFLAEGAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.8%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.8%)" "IPR001672 (20.2%) IPR018189 (20.2%) IPR035476 (20.2%)" "Phosphoglucose isomerase (PGI) (20.2%) Phosphoglucose isomerase, conserved site (20.2%) Phosphoglucose isomerase, SIS domain 1 (20.2%)" VLPELNGK root "1.2.1.- (55.3%) 1.2.1.12 (43.9%) 2.6.99.- (0.2%)" "With NAD(+) or NADP(+) as acceptor (55.3%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (43.9%) Transferring other nitrogenous groups (0.2%)" "GO:0006006 (12.7%) GO:0006096 (9.8%) GO:0006915 (3.3%)" "GO:0005829 (9.1%) GO:0005856 (3.3%) GO:0005634 (3.3%)" "GO:0051287 (15.7%) GO:0050661 (12.9%) GO:0004365 (11.8%)" "glucose metabolic process (12.7%) glycolytic process (9.8%) apoptotic process (3.3%)" "cytosol (9.1%) cytoskeleton (3.3%) nucleus (3.3%)" "NAD binding (15.7%) NADP binding (12.9%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (11.8%)" "IPR020829 (18.6%) IPR020831 (18.6%) IPR036291 (16.7%)" "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (18.6%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (18.6%) NAD(P)-binding domain superfamily (16.7%)" QALLAQLMQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) WYYMDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.4%) "GO:0004556 (32.3%) GO:0043169 (32.3%)" carbohydrate metabolic process (35.4%) "alpha-amylase activity (32.3%) cation binding (32.3%)" "IPR006047 (35.4%) IPR006046 (32.3%) IPR017853 (32.3%)" "Glycosyl hydrolase family 13, catalytic domain (35.4%) Alpha amylase (32.3%) Glycoside hydrolase superfamily (32.3%)" AEYAFLGR root "GO:0000917 (30.2%) GO:0030026 (0.5%) GO:0051301 (0.5%)" "GO:0016020 (2.4%) GO:0012505 (0.5%)" "GO:0005525 (31.1%) GO:0046872 (30.7%) GO:0004672 (1.9%)" "division septum assembly (30.2%) intracellular manganese ion homeostasis (0.5%) cell division (0.5%)" "membrane (2.4%) endomembrane system (0.5%)" "GTP binding (31.1%) metal ion binding (30.7%) protein kinase activity (1.9%)" "IPR006073 (23.6%) IPR019987 (23.2%) IPR030393 (23.2%)" "GTP binding domain (23.6%) GTP-binding protein, ribosome biogenesis, YsxC (23.2%) EngB-type guanine nucleotide-binding (G) domain (23.2%)" EFASAEEQLAFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.4%) GO:0006002 (13.6%)" GO:0005829 (14.4%) "GO:0003872 (14.4%) GO:0005524 (14.4%) GO:0046872 (14.4%)" "response to glucose (14.4%) fructose 6-phosphate metabolic process (13.6%)" cytosol (14.4%) "6-phosphofructokinase activity (14.4%) ATP binding (14.4%) metal ion binding (14.4%)" "IPR000023 (25.7%) IPR011183 (25.7%) IPR022953 (24.3%)" "Phosphofructokinase domain (25.7%) Pyrophosphate-dependent phosphofructokinase PfpB (25.7%) ATP-dependent 6-phosphofructokinase (24.3%)" RFNDGDVLTVEPWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.99.1 (100%) Deleted entry (100%) "GO:0009060 (24.3%) GO:0022904 (24.3%)" "GO:0009055 (24.3%) GO:0051537 (24.3%) GO:0016491 (2.9%)" "aerobic respiration (24.3%) respiratory electron transport chain (24.3%)" "electron transfer activity (24.3%) 2 iron, 2 sulfur cluster binding (24.3%) oxidoreductase activity (2.9%)" "IPR006058 (13.7%) IPR009051 (13.7%) IPR012675 (13.7%)" "2Fe-2S ferredoxin, iron-sulphur binding site (13.7%) Alpha-helical ferredoxin (13.7%) Beta-grasp domain superfamily (13.7%)" LAAGELPSYK Bacteria Bacteria 2.1.1.- (100%) Methyltransferases (100%) "GO:0009117 (49.8%) GO:0032259 (0.4%)" "GO:0003824 (44.1%) GO:0016787 (5.2%) GO:0008168 (0.4%)" "nucleotide metabolic process (49.8%) methylation (0.4%)" "catalytic activity (44.1%) hydrolase activity (5.2%) methyltransferase activity (0.4%)" "IPR001310 (33%) IPR011146 (33%) IPR036265 (32.8%)" "Histidine triad (HIT) protein (33%) HIT-like domain (33%) HIT-like superfamily (32.8%)" FASDVLER root "1.1.1.58 (63.6%) 2.6.1.9 (18.2%) 5.4.2.8 (18.2%)" "tagaturonate reductase (63.6%) histidinol-phosphate transaminase (18.2%) phosphomannomutase (18.2%)" "GO:0019592 (26.3%) GO:0000105 (1.8%) GO:0005975 (1.8%)" "GO:0005829 (26.3%) GO:0016020 (1.8%)" "GO:0008926 (26.3%) GO:0009026 (5.3%) GO:0016868 (1.8%)" "mannitol catabolic process (26.3%) L-histidine biosynthetic process (1.8%) carbohydrate metabolic process (1.8%)" "cytosol (26.3%) membrane (1.8%)" "mannitol-1-phosphate 5-dehydrogenase activity (26.3%) tagaturonate reductase activity (5.3%) intramolecular phosphotransferase activity (1.8%)" "IPR013118 (16.9%) IPR013131 (16.9%) IPR008927 (15.3%)" "Mannitol dehydrogenase, C-terminal (16.9%) Mannitol dehydrogenase, N-terminal (16.9%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (15.3%)" NFEQVEAALQDNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.3%) IPR006235 (17.3%) IPR054542 (17.3%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.3%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.3%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (17.3%)" VSEEDVNLACR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.3%) GO:0042597 (33.3%) GO:0008422 (33.3%) glucan catabolic process (33.3%) periplasmic space (33.3%) beta-glucosidase activity (33.3%) "IPR001764 (11.3%) IPR002772 (11.3%) IPR019800 (11.3%)" "Glycoside hydrolase, family 3, N-terminal (11.3%) Glycoside hydrolase family 3 C-terminal domain (11.3%) Glycoside hydrolase, family 3, active site (11.3%)" FMGETYAQSQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (33.8%) GO:0140662 (33.8%) GO:0051082 (32.4%)" "ATP binding (33.8%) ATP-dependent protein folding chaperone (33.8%) unfolded protein binding (32.4%)" "IPR013126 (17%) IPR018181 (17%) IPR043129 (17%)" "Heat shock protein 70 family (17%) Heat shock protein 70, conserved site (17%) ATPase, nucleotide binding domain (17%)" FCFEGFLPQK Bacteria Bacteria 2.1.1.198 (100%) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (100%) "GO:0032259 (1.2%) GO:0006364 (1%)" "GO:0005737 (48.4%) GO:0016020 (0.8%)" "GO:0070677 (47.4%) GO:0008168 (1.2%)" "methylation (1.2%) rRNA processing (1%)" "cytoplasm (48.4%) membrane (0.8%)" "rRNA (cytosine-2'-O-)-methyltransferase activity (47.4%) methyltransferase activity (1.2%)" "IPR000878 (16.8%) IPR008189 (16.8%) IPR014776 (16.7%)" "Tetrapyrrole methylase (16.8%) rRNA small subunit methyltransferase I (16.8%) Tetrapyrrole methylase, subdomain 2 (16.7%)" VQYDLNTAGPNNTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) EMESSLFSMLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.1%) IPR010918 (11.1%) IPR029062 (11.1%)" "Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain (11.1%) Class I glutamine amidotransferase-like (11.1%)" QLEMELPLNVHTLYSNEHNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.4%) GO:0005886 (25.4%) "GO:0000286 (25.4%) GO:0000166 (23.9%)" L-alanine catabolic process (25.4%) plasma membrane (25.4%) "alanine dehydrogenase activity (25.4%) nucleotide binding (23.9%)" "IPR007698 (20%) IPR007886 (20%) IPR008141 (20%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20%) Alanine dehydrogenase (20%)" FVPGAAGTTVALPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR001764 (13.2%) IPR050288 (13.2%) IPR002772 (12.5%)" "Glycoside hydrolase, family 3, N-terminal (13.2%) Cellulose-degrading glycosyl hydrolase 3 (13.2%) Glycoside hydrolase family 3 C-terminal domain (12.5%)" LEQTLFHQGSLWGDKSQDEER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" DVMLDAPSELDPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004815 (20%) GO:0005524 (20%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) aspartate-tRNA ligase activity (20%) ATP binding (20%)" "IPR004364 (9.2%) IPR004365 (9.2%) IPR004524 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (9.2%) Aspartate-tRNA ligase, type 1 (9.2%)" TDFQGYPLRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" EFEYFPFEPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (19.9%) GO:0005829 (19.9%) "GO:0004335 (19.9%) GO:0005524 (19.9%) GO:0046872 (19.9%)" galactose metabolic process (19.9%) cytosol (19.9%) "galactokinase activity (19.9%) ATP binding (19.9%) metal ion binding (19.9%)" "IPR000705 (10.2%) IPR006203 (10.2%) IPR006204 (10.2%)" "Galactokinase (10.2%) GHMP kinase, ATP-binding, conserved site (10.2%) GHMP kinase N-terminal domain (10.2%)" LLDLASTQFPDGGCYHQYQPLTK Bacteria Bacteria 2.4.1.20 (100%) cellobiose phosphorylase (100%) GO:0005975 (33.1%) "GO:0030246 (32.8%) GO:0016757 (31.6%) GO:0047738 (1.5%)" carbohydrate metabolic process (33.1%) "carbohydrate binding (32.8%) glycosyltransferase activity (31.6%) cellobiose phosphorylase activity (1.5%)" "IPR033432 (12.6%) IPR052047 (12.6%) IPR010383 (12.5%)" "Glycosyl hydrolase 94, catalytic domain (12.6%) Glycosyl Hydrolase 94 Enzymes (12.6%) Glycosyl hydrolase 94, supersandwich domain (12.5%)" VWVNPEGGWCGKDDVLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (42.3%) "GO:0015926 (42.3%) GO:0031218 (15.4%)" pectin catabolic process (42.3%) "glucosidase activity (42.3%) arabinogalactan endo-1,4-beta-galactosidase activity (15.4%)" "IPR011683 (51.2%) IPR017853 (48.8%)" "Glycosyl hydrolase family 53 (51.2%) Glycoside hydrolase superfamily (48.8%)" YANVDWQDALFKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.4%) IPR023997 (15.4%) IPR039426 (15.4%)" "TonB-dependent receptor, plug domain (15.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.4%) TonB-dependent receptor-like (15.4%)" EFLPQFEALGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (58.8%) "GO:0016787 (23.5%) GO:0016829 (17.6%)" carbohydrate metabolic process (58.8%) "hydrolase activity (23.5%) lyase activity (17.6%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" DKNETANTVALQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (66.7%) IPR008160 (33.3%)" "Domain of unknown function DUF4988 (66.7%) Collagen triple helix repeat (33.3%)" LALGLAGNSSNTTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0032259 (20.4%) GO:0006364 (18.5%)" GO:0005737 (20.4%) "GO:0003723 (20.4%) GO:0008168 (20.4%)" "methylation (20.4%) rRNA processing (18.5%)" cytoplasm (20.4%) "RNA binding (20.4%) methyltransferase activity (20.4%)" "IPR002478 (17.5%) IPR019614 (17.5%) IPR041532 (17.5%)" "PUA domain (17.5%) S-adenosylmethionine-dependent methyltransferase (17.5%) RlmI-like, PUA domain (17.5%)" EMELFMFSER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.6%) GO:0005737 (16.6%) "GO:0000049 (16.6%) GO:0004829 (16.6%) GO:0005524 (16.6%)" threonyl-tRNA aminoacylation (16.6%) cytoplasm (16.6%) "tRNA binding (16.6%) threonine-tRNA ligase activity (16.6%) ATP binding (16.6%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004154 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) Anticodon-binding (7.7%)" KFLDLALR root "2.7.11.1 (80%) 3.2.1.8 (10%) 2.1.1.72 (3.3%)" "non-specific serine/threonine protein kinase (80%) endo-1,4-beta-xylanase (10%) site-specific DNA-methyltransferase (adenine-specific) (3.3%)" "GO:0045893 (13.1%) GO:0005975 (3.8%) GO:0050832 (0.8%)" "GO:0005829 (13.4%) GO:0032993 (13.1%) GO:0016020 (2.2%)" "GO:0042802 (13.2%) GO:0000156 (13.1%) GO:0000987 (13%)" "positive regulation of DNA-templated transcription (13.1%) carbohydrate metabolic process (3.8%) defense response to fungus (0.8%)" "cytosol (13.4%) protein-DNA complex (13.1%) membrane (2.2%)" "identical protein binding (13.2%) phosphorelay response regulator activity (13.1%) cis-regulatory region sequence-specific DNA binding (13%)" "IPR001789 (11.8%) IPR011006 (11.8%) IPR036388 (11.8%)" "Signal transduction response regulator, receiver domain (11.8%) CheY-like superfamily (11.8%) Winged helix-like DNA-binding domain superfamily (11.8%)" GGEVELEQFWLQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) IPR023614 (100%) Porin domain superfamily (100%) YSEVLLWYAESAAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR011990 (32.6%) IPR033985 (32.6%)" "RagB/SusD domain (34.8%) Tetratricopeptide-like helical domain superfamily (32.6%) SusD-like, N-terminal (32.6%)" TGKLEQTSLYDACLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (78.6%) GO:0015344 (21.4%) cell outer membrane (78.6%) siderophore uptake transmembrane transporter activity (21.4%) "IPR036942 (78.6%) IPR039426 (21.4%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (78.6%) TonB-dependent receptor-like (21.4%)" FPSTLWAEYLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" LYTFVSNHPLGGQDGVCLGSLLGK Pseudomonadati Bacteria Pseudomonadati GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) ESVVGALSQVSSDDLLNTPTANVTQALAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" ENPSDLPLATGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.7%) IPR001375 (21%) IPR011042 (19.6%)" "WD40-like beta-propeller (21.7%) Peptidase S9, prolyl oligopeptidase, catalytic domain (21%) Six-bladed beta-propeller, TolB-like (19.6%)" AGGQMAHAYTYDALYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (47.1%) GO:0005737 (47.1%) GO:0016020 (5.9%)" "extracellular region (47.1%) cytoplasm (47.1%) membrane (5.9%)" "IPR050708 (18.4%) IPR022385 (17.3%) IPR006530 (16.3%)" "Type VI secretion system VgrG/RHS (18.4%) Rhs repeat-associated core (17.3%) YD repeat (16.3%)" FYNADDPVYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005615 (57.1%) GO:0005737 (14.3%) GO:0005886 (14.3%)" "extracellular space (57.1%) cytoplasm (14.3%) plasma membrane (14.3%)" "IPR001611 (17.2%) IPR027899 (15.2%) IPR032675 (15.2%)" "Leucine-rich repeat (17.2%) Domain of unknown function DUF4458 (15.2%) Leucine-rich repeat domain superfamily (15.2%)" YAVTDMSNDVMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20.5%) GO:0044550 (20.5%)" GO:0005737 (19.2%) "GO:0004315 (20.5%) GO:0033818 (19.2%)" "fatty acid biosynthetic process (20.5%) secondary metabolite biosynthetic process (20.5%)" cytoplasm (19.2%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20.5%) beta-ketoacyl-acyl-carrier-protein synthase III activity (19.2%)" "IPR013747 (25.4%) IPR013751 (25.4%) IPR016039 (25.4%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25.4%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25.4%) Thiolase-like (25.4%)" ADLFDAPEYLEYHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.7%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.7%)" MFEDMGVMK root 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.6%) GO:0004356 (51.4%) glutamine biosynthetic process (48.6%) glutamine synthetase activity (51.4%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" DQELFDLLER Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (17.4%) GO:0035999 (16.8%) GO:0032259 (6.6%)" GO:0005829 (17.4%) "GO:0004372 (17.4%) GO:0030170 (17.4%) GO:0008168 (6.6%)" "glycine biosynthetic process from serine (17.4%) tetrahydrofolate interconversion (16.8%) methylation (6.6%)" cytosol (17.4%) "glycine hydroxymethyltransferase activity (17.4%) pyridoxal phosphate binding (17.4%) methyltransferase activity (6.6%)" "IPR039429 (14.6%) IPR049943 (14.6%) IPR001085 (14.1%)" "Serine hydroxymethyltransferase-like domain (14.6%) Serine hydroxymethyltransferase-like (14.6%) Serine hydroxymethyltransferase (14.1%)" AGLAPVKPLMDELEAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" SVMGTEELQVAEPEEVKQEFGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.-.-.- (100%) Translocases (100%) GO:0022900 (25%) GO:0005886 (25%) "GO:0009055 (25%) GO:0010181 (25%)" electron transport chain (25%) plasma membrane (25%) "electron transfer activity (25%) FMN binding (25%)" "IPR007329 (50%) IPR010209 (50%)" "FMN-binding (50%) Ion-translocating oxidoreductase complex, subunit RnfG/RsxG (50%)" LNLHDLADADLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.7%) GO:0006164 (0.6%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.6%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR010918 (11.5%) IPR010073 (11.1%) IPR036676 (11.1%)" "PurM-like, C-terminal domain (11.5%) Phosphoribosylformylglycinamidine synthase PurL (11.1%) PurM-like, C-terminal domain superfamily (11.1%)" EALDNNPGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella VLLNGLGKDAAQLLSR Bacteria Bacteria IPR025964 (100%) GGGtGRT protein (100%) NLSQDTYGNSSSPGYNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" DELAQVLMNNPQLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016787 (100%) hydrolase activity (100%) "IPR003495 (23.8%) IPR011629 (23.8%) IPR051927 (23.8%)" "CobW/HypB/UreG, nucleotide-binding domain (23.8%) Zinc chaperone CobW-like, C-terminal (23.8%) Zinc Chaperone and cDPG Synthetase (23.8%)" NYTSPYNLDFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR030890 (100%) Substrate import-associated zinc metallohydrolase lipoprotein (100%) VACLEELAFK root 2.7.7.24 (100%) glucose-1-phosphate thymidylyltransferase (100%) "GO:0008879 (49.5%) GO:0046872 (49%) GO:0016779 (1.5%)" "glucose-1-phosphate thymidylyltransferase activity (49.5%) metal ion binding (49%) nucleotidyltransferase activity (1.5%)" "IPR005835 (33.6%) IPR005907 (33.6%) IPR029044 (32.9%)" "Nucleotidyl transferase domain (33.6%) Glucose-1-phosphate thymidylyltransferase, short form (33.6%) Nucleotide-diphospho-sugar transferases (32.9%)" LTSDLLDAALAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (48.9%) GO:0003746 (51.1%) cytoplasm (48.9%) translation elongation factor activity (51.1%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" APLQSYELSLNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (2.8%) GO:0009279 (94.4%) GO:0015344 (2.8%) siderophore transmembrane transport (2.8%) cell outer membrane (94.4%) siderophore uptake transmembrane transporter activity (2.8%) "IPR012910 (12.9%) IPR023997 (12.9%) IPR039426 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%) TonB-dependent receptor-like (12.9%)" TNTFGAVMR root 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.2%) "GO:0005737 (18.7%) GO:0005739 (0.7%)" "GO:0005524 (20.2%) GO:0003676 (19.9%) GO:0004816 (19.9%)" asparaginyl-tRNA aminoacylation (20.2%) "cytoplasm (18.7%) mitochondrion (0.7%)" "ATP binding (20.2%) nucleic acid binding (19.9%) asparagine-tRNA ligase activity (19.9%)" "IPR004364 (14.5%) IPR006195 (14.4%) IPR045864 (14.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (14.5%) Aminoacyl-tRNA synthetase, class II (14.4%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.4%)" NAGLGSETLWQSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (20%) IPR013783 (20%) IPR017853 (20%)" "Glycoside hydrolase, family 5 (20%) Immunoglobulin-like fold (20%) Glycoside hydrolase superfamily (20%)" TLSQLLSSDYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25%) IPR027417 (25%) IPR041628 (25%)" "ATPase, AAA-3 (25%) P-loop containing nucleoside triphosphate hydrolase (25%) ChlI/MoxR, AAA lid domain (25%)" AVEKDLDCAAEALQYAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" KDFVADPGLHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0042907 (50%) plasma membrane (50%) xanthine transmembrane transporter activity (50%) "IPR006042 (50%) IPR006043 (50%)" "Xanthine/uracil permease (50%) Nucleobase cation symporter 2 family (50%)" MTDAATAGSVNLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025970 (33.3%) IPR033404 (33.3%) IPR033407 (33.3%)" "SusE outer membrane protein (33.3%) Domain of unknown function DUF5111 (33.3%) Domain of unknown function DUF5114 (33.3%)" MKASEVLANLQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.4%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.4%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" LPAYYFDNAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" LLTEEGLGTSYLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (20%)" GO:0005737 (20%) "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (20%)" cytoplasm (20%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" LGYNYVSPMYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) AVAFNENLQPSWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (17.1%) GO:0035999 (17.1%) GO:0032259 (7.3%)" GO:0005829 (17.1%) "GO:0004372 (17.1%) GO:0030170 (17.1%) GO:0008168 (7.3%)" "glycine biosynthetic process from serine (17.1%) tetrahydrofolate interconversion (17.1%) methylation (7.3%)" cytosol (17.1%) "glycine hydroxymethyltransferase activity (17.1%) pyridoxal phosphate binding (17.1%) methyltransferase activity (7.3%)" "IPR001085 (14.6%) IPR019798 (14.6%) IPR039429 (14.6%)" "Serine hydroxymethyltransferase (14.6%) Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.6%) Serine hydroxymethyltransferase-like domain (14.6%)" YAQELVK root "4.1.1.49 (32.6%) 1.2.4.2 (7.6%) 6.1.1.3 (6.5%)" "phosphoenolpyruvate carboxykinase (ATP) (32.6%) oxoglutarate dehydrogenase (succinyl-transferring) (7.6%) threonine--tRNA ligase (6.5%)" "GO:0006094 (5.4%) GO:0006435 (1.1%) GO:0006099 (0.9%)" "GO:0005829 (9.6%) GO:0005737 (3.7%) GO:0005634 (2%)" "GO:0005524 (9.3%) GO:0046872 (7.1%) GO:0004612 (5.4%)" "gluconeogenesis (5.4%) threonyl-tRNA aminoacylation (1.1%) tricarboxylic acid cycle (0.9%)" "cytosol (9.6%) cytoplasm (3.7%) nucleus (2%)" "ATP binding (9.3%) metal ion binding (7.1%) phosphoenolpyruvate carboxykinase (ATP) activity (5.4%)" "IPR001272 (4.5%) IPR013035 (4.5%) IPR008210 (4.3%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (4.5%) Phosphoenolpyruvate carboxykinase, C-terminal (4.5%) Phosphoenolpyruvate carboxykinase, N-terminal (4.3%)" LVVADGEVEDENKELTLSEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006353 (19.2%) GO:0031564 (19.2%)" GO:0005829 (19.2%) "GO:0003700 (19.2%) GO:0003723 (19.2%) GO:0003746 (3.8%)" "DNA-templated transcription termination (19.2%) transcription antitermination (19.2%)" cytosol (19.2%) "DNA-binding transcription factor activity (19.2%) RNA binding (19.2%) translation elongation factor activity (3.8%)" "IPR003029 (11.1%) IPR009019 (11.1%) IPR010213 (11.1%)" "S1 domain (11.1%) K homology domain superfamily, prokaryotic type (11.1%) Transcription factor NusA (11.1%)" TQFDTELEEALGEYEDGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (69.2%) IPR011250 (30.8%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (69.2%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (30.8%)" KAGWDTHGLPVELGVEK root 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.2%) "GO:0004822 (14.4%) GO:0005524 (14.4%) GO:0002161 (14.2%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.2%) "isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%) aminoacyl-tRNA deacylase activity (14.2%)" "IPR002300 (12.1%) IPR023586 (12.1%) IPR014729 (12%)" "Aminoacyl-tRNA synthetase, class Ia (12.1%) Isoleucine-tRNA ligase, type 2 (12.1%) Rossmann-like alpha/beta/alpha sandwich fold (12%)" LFELSQRPEFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (90%) 2.4.1.8 (10%)" "glycogen phosphorylase (90%) maltose phosphorylase (10%)" GO:0005975 (33.2%) "GO:0030170 (33.2%) GO:0008184 (32.6%) GO:0004645 (0.5%)" carbohydrate metabolic process (33.2%) "pyridoxal phosphate binding (33.2%) glycogen phosphorylase activity (32.6%) 1,4-alpha-oligoglucan phosphorylase activity (0.5%)" "IPR011834 (25.2%) IPR052182 (25.2%) IPR000811 (24.8%)" "Alpha-glucan phosphorylase (25.2%) Glycogen_Maltodextrin_Phosphorylase (25.2%) Glycosyl transferase, family 35 (24.8%)" FNTHEEVEAFLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.1 (100%) DNA topoisomerase (100%) GO:0006265 (25.6%) "GO:0003677 (25.6%) GO:0003917 (25.6%) GO:0046872 (23.2%)" DNA topological change (25.6%) "DNA binding (25.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (25.6%) metal ion binding (23.2%)" "IPR000380 (7.5%) IPR003601 (7.5%) IPR006171 (7.5%)" "DNA topoisomerase, type IA (7.5%) DNA topoisomerase, type IA, domain 2 (7.5%) TOPRIM domain (7.5%)" LNQDWDYLQASNNFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (49.7%) "GO:0003824 (32.6%) GO:0016787 (15.5%) GO:0004556 (2.1%)" carbohydrate metabolic process (49.7%) "catalytic activity (32.6%) hydrolase activity (15.5%) alpha-amylase activity (2.1%)" "IPR004300 (33.6%) IPR052046 (33.6%) IPR011330 (32.9%)" "Glycoside hydrolase family 57, N-terminal domain (33.6%) Glycosyl hydrolase family 57 (33.6%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.9%)" ENADEAMDCATCLGCGACVAACK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.3.99.1 (100%) Deleted entry (100%) "GO:0009060 (23.5%) GO:0022904 (23.5%)" "GO:0009055 (23.5%) GO:0051537 (23.5%) GO:0016491 (6.2%)" "aerobic respiration (23.5%) respiratory electron transport chain (23.5%)" "electron transfer activity (23.5%) 2 iron, 2 sulfur cluster binding (23.5%) oxidoreductase activity (6.2%)" "IPR006058 (13.8%) IPR009051 (13.8%) IPR012675 (13.8%)" "2Fe-2S ferredoxin, iron-sulphur binding site (13.8%) Alpha-helical ferredoxin (13.8%) Beta-grasp domain superfamily (13.8%)" VCALGTSVMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.99.17 (100%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (100%) GO:0002099 (34.5%) GO:0005737 (30.9%) GO:0051075 (34.5%) tRNA wobble guanine modification (34.5%) cytoplasm (30.9%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (34.5%) "IPR003699 (27.1%) IPR036100 (24.3%) IPR042118 (24.3%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA (27.1%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily (24.3%) QueA, domain 1 (24.3%)" YYFVPEPVVVGGYTLTPQSSAADTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (62.5%) IPR008160 (37.5%)" "Domain of unknown function DUF4988 (62.5%) Collagen triple helix repeat (37.5%)" ELVRPLNGQAGDLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" YQYFNTSWADQLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" FTNLFLDAEHSGVAGENSWGAWPLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) "GO:0005990 (24.7%) GO:0005975 (0.7%)" GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24%)" "lactose catabolic process (24.7%) carbohydrate metabolic process (0.7%)" beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24%)" "IPR004199 (7.5%) IPR006102 (7.3%) IPR006103 (7.3%)" "Beta galactosidase small chain/ domain 5 (7.5%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.3%) Glycoside hydrolase family 2, catalytic domain (7.3%)" LLQGGGGGQPHYAQAGGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004813 (14.3%)" alanyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) alanine-tRNA ligase activity (14.3%)" "IPR002318 (9.2%) IPR003156 (9.2%) IPR012947 (9.2%)" "Alanine-tRNA ligase, class IIc (9.2%) DHHA1 domain (9.2%) Threonyl/alanyl tRNA synthetase, SAD (9.2%)" VVEVPASNLK Bacteria Bacteria GO:0006412 (16.8%) "GO:0005840 (16.8%) GO:1990904 (16.8%) GO:0005737 (16.2%)" "GO:0003735 (16.8%) GO:0019843 (16.5%)" translation (16.8%) "ribosome (16.8%) ribonucleoprotein complex (16.8%) cytoplasm (16.2%)" "structural constituent of ribosome (16.8%) rRNA binding (16.5%)" "IPR000630 (35.3%) IPR035987 (35.3%) IPR047863 (29.5%)" "Small ribosomal subunit protein uS8 (35.3%) Small ribosomal subunit protein uS8 superfamily (35.3%) Small ribosomal subunit protein uS8, conserved site (29.5%)" DFLAGWDFYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (43.1%) "GO:0052689 (43.1%) GO:0004557 (13.7%)" cell outer membrane (43.1%) "carboxylic ester hydrolase activity (43.1%) alpha-galactosidase activity (13.7%)" "IPR032812 (25.6%) IPR044060 (25.6%) IPR011050 (24.4%)" "SbsA, Ig-like domain (25.6%) Bacterial repeat domain (25.6%) Pectin lyase fold/virulence factor (24.4%)" LFGDLPFK root "4.2.3.1 (42.9%) 5.3.1.- (28.6%) 5.-.-.- (14.3%)" "threonine synthase (42.9%) Interconverting aldoses and ketoses (28.6%) Isomerases (14.3%)" "GO:0009401 (4.6%) GO:1901135 (4.6%) GO:0009088 (3.1%)" "GO:0009279 (44.6%) GO:0005886 (4.6%) GO:0005829 (1.5%)" "GO:0016787 (6.2%) GO:0016853 (4.6%) GO:0097367 (4.6%)" "phosphoenolpyruvate-dependent sugar phosphotransferase system (4.6%) carbohydrate derivative metabolic process (4.6%) threonine biosynthetic process (3.1%)" "cell outer membrane (44.6%) plasma membrane (4.6%) cytosol (1.5%)" "hydrolase activity (6.2%) isomerase activity (4.6%) carbohydrate derivative binding (4.6%)" "IPR011990 (21.5%) IPR033985 (20.1%) IPR012944 (19.5%)" "Tetratricopeptide-like helical domain superfamily (21.5%) SusD-like, N-terminal (20.1%) RagB/SusD domain (19.5%)" AQESALVMLEDFTFEAPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20.5%) "GO:0005840 (20.5%) GO:1990904 (20.5%)" "GO:0003735 (20.5%) GO:0019843 (18.2%)" translation (20.5%) "ribosome (20.5%) ribonucleoprotein complex (20.5%)" "structural constituent of ribosome (20.5%) rRNA binding (18.2%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" LAGDLPAYLALGVGYSPVNAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (84%) IPR011250 (16%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (84%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16%)" LFDHDVDLSYSTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.99.19 (100%) 2-iminoacetate synthase (100%) "GO:0009228 (23.1%) GO:0009229 (0.1%)" GO:1902508 (0.1%) "GO:0051539 (25.9%) GO:0005506 (25.4%) GO:0003824 (21.6%)" "thiamine biosynthetic process (23.1%) thiamine diphosphate biosynthetic process (0.1%)" 2-iminoacetate synthase complex (0.1%) "4 iron, 4 sulfur cluster binding (25.9%) iron ion binding (25.4%) catalytic activity (21.6%)" "IPR034428 (20.2%) IPR010722 (20.1%) IPR013785 (20%)" "ThiH/NocL/HydG-like (20.2%) Biotin and thiamin synthesis-associated domain (20.1%) Aldolase-type TIM barrel (20%)" NALVTSFNR root "4.2.1.3 (96.4%) 4.2.1.- (3.6%)" "aconitate hydratase (96.4%) Hydro-lyases (3.6%)" GO:0006099 (19.7%) "GO:0005829 (19.7%) GO:0005739 (1.8%)" "GO:0003994 (19.7%) GO:0051539 (19.7%) GO:0046872 (19.4%)" tricarboxylic acid cycle (19.7%) "cytosol (19.7%) mitochondrion (1.8%)" "aconitate hydratase activity (19.7%) 4 iron, 4 sulfur cluster binding (19.7%) metal ion binding (19.4%)" "IPR000573 (11.3%) IPR001030 (11.3%) IPR018136 (11.3%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.3%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.3%) Aconitase family, 4Fe-4S cluster binding site (11.3%)" NMFAFLDAPYDVPTTDFEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR025393 (50.7%) IPR029044 (49.3%)" "Domain of unknown function DUF4301 (50.7%) Nucleotide-diphospho-sugar transferases (49.3%)" QVELVNNMEGLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (49.1%) GO:0015562 (50.9%) plasma membrane (49.1%) efflux transmembrane transporter activity (50.9%) "IPR003423 (33.7%) IPR050737 (33.7%) IPR010131 (32.6%)" "Outer membrane efflux protein (33.7%) Unknown (33.7%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (32.6%)" VLDDVKNEVEVQLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (25.9%) IPR012131 (25.9%) IPR016161 (24.1%)" "Histidinol dehydrogenase, conserved site (25.9%) Histidinol dehydrogenase (25.9%) Aldehyde/histidinol dehydrogenase (24.1%)" MGAANSLLLK root 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.6%) GO:0009986 (16.4%)" "GO:0000287 (16.7%) GO:0004634 (16.7%) GO:0016787 (0.1%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.6%) cell surface (16.4%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%) hydrolase activity (0.1%)" "IPR000941 (16.7%) IPR020809 (16.7%) IPR020810 (16.7%)" "Enolase (16.7%) Enolase, conserved site (16.7%) Enolase, C-terminal TIM barrel domain (16.7%)" LPFGELTTVVPSQLVATPSPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" ELLEQYGYEEDTPLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.4%) GO:0032045 (14.4%)" "GO:0003746 (14.4%) GO:0003924 (14.4%) GO:0005525 (14.4%)" "cytosol (14.4%) guanyl-nucleotide exchange factor complex (14.4%)" "translation elongation factor activity (14.4%) GTPase activity (14.4%) GTP binding (14.4%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" LATELYLK root "6.1.1.6 (98.3%) 2.3.2.3 (0.7%) 2.3.1.15 (0.3%)" "lysine--tRNA ligase (98.3%) lysyltransferase (0.7%) glycerol-3-phosphate 1-O-acyltransferase (0.3%)" "GO:0006430 (14.8%) GO:0006431 (0.2%) GO:0006631 (0.1%)" "GO:0005829 (14.8%) GO:0005737 (0.1%) GO:0005886 (0.1%)" "GO:0005524 (14.9%) GO:0004824 (14.9%) GO:0000049 (14.8%)" "lysyl-tRNA aminoacylation (14.8%) methionyl-tRNA aminoacylation (0.2%) fatty acid metabolic process (0.1%)" "cytosol (14.8%) cytoplasm (0.1%) plasma membrane (0.1%)" "ATP binding (14.9%) lysine-tRNA ligase activity (14.9%) tRNA binding (14.8%)" "IPR004364 (11.8%) IPR018149 (11.8%) IPR006195 (11.8%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (11.8%) Lysyl-tRNA synthetase, class II, C-terminal (11.8%) Aminoacyl-tRNA synthetase, class II (11.8%)" VVYLPYEATNLLGSLGGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20.2%) IPR018080 (20.2%) IPR036013 (20.2%)" "Band 7 domain (20.2%) Band 7/stomatin-like, conserved site (20.2%) Band 7/SPFH domain superfamily (20.2%)" GGGGTGDTGYHDVELWSTLTSTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" MEVLNALGR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20.1%) IPR020574 (20.1%) IPR023035 (20.1%)" "Small ribosomal subunit protein uS9 (20.1%) Small ribosomal subunit protein uS9, conserved site (20.1%) Small ribosomal subunit protein uS9, bacteria/plastid (20.1%)" QEGDTNVTTETGAGQWGAALSYAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (22.1%) IPR006316 (22.1%) IPR023026 (22.1%)" "Tryptophan synthase beta chain-like, PALP domain (22.1%) Tryptophan synthase, beta chain-like (22.1%) Tryptophan synthase beta chain/beta chain-like (22.1%)" VGLLGAAGYTGGELLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.2.1.38 (100%) N-acetyl-gamma-glutamyl-phosphate reductase (100%) GO:0006526 (20%) GO:0005737 (20%) "GO:0003942 (20%) GO:0051287 (20%) GO:0070401 (20%)" L-arginine biosynthetic process (20%) cytoplasm (20%) "N-acetyl-gamma-glutamyl-phosphate reductase activity (20%) NAD binding (20%) NADP+ binding (20%)" "IPR000534 (20.1%) IPR000706 (20.1%) IPR023013 (20.1%)" "Semialdehyde dehydrogenase, NAD-binding (20.1%) N-acetyl-gamma-glutamyl-phosphate reductase, type 1 (20.1%) N-acetyl-gamma-glutamyl-phosphate reductase, active site (20.1%)" TTDLALLK root "3.4.21.107 (35.6%) 4.2.2.29 (33.6%) 3.4.21.- (14.8%)" "peptidase Do (35.6%) peptidoglycan lytic transglycosylase (33.6%) Serine endopeptidases (14.8%)" "GO:0006508 (24.2%) GO:0071555 (4.6%) GO:0009252 (4.3%)" "GO:0005886 (5.5%) GO:0016020 (4.2%) GO:0005829 (2.9%)" "GO:0004252 (25%) GO:0008932 (4.3%) GO:0017168 (1.6%)" "proteolysis (24.2%) cell wall organization (4.6%) peptidoglycan biosynthetic process (4.3%)" "plasma membrane (5.5%) membrane (4.2%) cytosol (2.9%)" "serine-type endopeptidase activity (25%) lytic endotransglycosylase activity (4.3%) 5-oxoprolinase (ATP-hydrolyzing) activity (1.6%)" "IPR009003 (15.5%) IPR001478 (15.3%) IPR001940 (15.2%)" "Peptidase S1, PA clan (15.5%) PDZ domain (15.3%) Peptidase S1C (15.2%)" NNQFWYQEAMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.4%) IPR003385 (20.4%) IPR013783 (19.7%)" "Carbohydrate binding module family 20 (20.4%) Glycoside hydrolase, family 77 (20.4%) Immunoglobulin-like fold (19.7%)" LFTESLLSNEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.5.2.6 (100%) beta-lactamase (100%) "GO:0030655 (31.7%) GO:0046677 (31.7%)" GO:0016020 (4.9%) GO:0008800 (31.7%) "beta-lactam antibiotic catabolic process (31.7%) response to antibiotic (31.7%)" membrane (4.9%) beta-lactamase activity (31.7%) "IPR000871 (26%) IPR045155 (26%) IPR012338 (24%)" "Beta-lactamase, class-A (26%) Beta-lactamase class A, catalytic domain (26%) Beta-lactamase/transpeptidase-like (24%)" TFFGYNDMADAK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "1.3.1.9 (99.1%) 1.3.1.10 (0.9%)" "enoyl-[acyl-carrier-protein] reductase (NADH) (99.1%) enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific) (0.9%)" GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (33.5%) IPR014358 (33.5%) IPR036291 (32.9%)" "Short-chain dehydrogenase/reductase SDR (33.5%) Enoyl-[acyl-carrier-protein] reductase (NADH) (33.5%) NAD(P)-binding domain superfamily (32.9%)" TTPSVVGFVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (33.6%) GO:0140662 (33.6%) GO:0051082 (32.8%)" "ATP binding (33.6%) ATP-dependent protein folding chaperone (33.6%) unfolded protein binding (32.8%)" "IPR013126 (16.9%) IPR018181 (16.9%) IPR043129 (16.9%)" "Heat shock protein 70 family (16.9%) Heat shock protein 70, conserved site (16.9%) ATPase, nucleotide binding domain (16.9%)" QVYENQGAMYER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (10.8%) GO:0004386 (0.3%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (10.8%) helicase activity (0.3%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR011115 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SecA DEAD-like, N-terminal (7.8%)" LAGETLYLYAPLANR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.1.7.2 (61.7%) 2.7.6.5 (38.3%)" "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (61.7%) GTP diphosphokinase (38.3%)" GO:0015969 (37.3%) GO:0005886 (37.2%) "GO:0016787 (10.8%) GO:0016301 (8.8%) GO:0008893 (3.8%)" guanosine tetraphosphate metabolic process (37.3%) plasma membrane (37.2%) "hydrolase activity (10.8%) kinase activity (8.8%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (3.8%)" "IPR007685 (9.1%) IPR004095 (9%) IPR033655 (9%)" "RelA/SpoT (9.1%) TGS (9%) RelA/SpoT, TGS domain (9%)" MNQQDLNQLSAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025393 (51.2%) IPR029044 (48.8%)" "Domain of unknown function DUF4301 (51.2%) Nucleotide-diphospho-sugar transferases (48.8%)" RGVEAFVPVWNVENCLQCNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" ALLMLFK root "2.7.8.- (12%) 1.10.3.- (8%) 3.4.11.9 (8%)" "Transferases for other substituted phosphate groups (12%) With oxygen as acceptor (8%) Xaa-Pro aminopeptidase (8%)" "GO:0000462 (1.3%) GO:0006508 (1.3%) GO:0045943 (1.3%)" "GO:0016020 (18.1%) GO:0005886 (16.6%) GO:0005829 (1.5%)" "GO:0008381 (3%) GO:0046872 (3%) GO:0051539 (2.6%)" "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (1.3%) proteolysis (1.3%) positive regulation of transcription by RNA polymerase I (1.3%)" "membrane (18.1%) plasma membrane (16.6%) cytosol (1.5%)" "mechanosensitive monoatomic ion channel activity (3%) metal ion binding (3%) 4 iron, 4 sulfur cluster binding (2.6%)" "IPR018580 (4.1%) IPR006685 (2.2%) IPR010920 (2.2%)" "Uncharacterised protein family YfhO (4.1%) Mechanosensitive ion channel MscS (2.2%) LSM domain superfamily (2.2%)" YLDQVSDSHLSDETK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044341 (33.3%) GO:0005886 (33.3%) GO:0005436 (33.3%) sodium-dependent phosphate transport (33.3%) plasma membrane (33.3%) sodium:phosphate symporter activity (33.3%) "IPR003841 (48.3%) IPR038078 (48.3%) IPR004633 (1.7%)" "Sodium-dependent phosphate transport protein (48.3%) PhoU-like domain superfamily (48.3%) Na/Pi-cotransporter II-related/YqeW-like protein (1.7%)" YTSNMPDGRPAGAPLAPGANPSYGAEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33.3%) GO:0005829 (33.3%) GO:0008861 (33.3%) glucose metabolic process (33.3%) cytosol (33.3%) formate C-acetyltransferase activity (33.3%) "IPR001150 (20%) IPR004184 (20%) IPR005949 (20%)" "Glycine radical domain (20%) Pyruvate formate lyase domain (20%) Formate acetyltransferase (20%)" NFTSFAAEWNSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (22.4%) IPR057601 (22.4%) IPR008969 (18.4%)" "TonB-dependent receptor-like (22.4%) TonB-dependent transporter Oar-like, beta-barrel domain (22.4%) Carboxypeptidase-like, regulatory domain superfamily (18.4%)" ELCNENLDVLNYSSNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006353 (20%) GO:0031564 (20%)" GO:0005829 (20%) "GO:0003723 (20%) GO:0003700 (17.8%) GO:0003746 (2.2%)" "DNA-templated transcription termination (20%) transcription antitermination (20%)" cytosol (20%) "RNA binding (20%) DNA-binding transcription factor activity (17.8%) translation elongation factor activity (2.2%)" "IPR025249 (12.5%) IPR030842 (12.5%) IPR003029 (11.1%)" "Transcription factor NusA, first KH domain (12.5%) Transcription factor NusA, prokaryotes (12.5%) S1 domain (11.1%)" FNKPLEELDTLYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) YTLQGMR root "GO:0044718 (30.4%) GO:0015074 (0.5%) GO:0031647 (0.5%)" "GO:0009279 (30.4%) GO:0016020 (1.1%) GO:0019005 (0.8%)" "GO:0015344 (30.4%) GO:0004180 (1.9%) GO:0003677 (0.5%)" "siderophore transmembrane transport (30.4%) DNA integration (0.5%) regulation of protein stability (0.5%)" "cell outer membrane (30.4%) membrane (1.1%) SCF ubiquitin ligase complex (0.8%)" "siderophore uptake transmembrane transporter activity (30.4%) carboxypeptidase activity (1.9%) DNA binding (0.5%)" "IPR039426 (18.9%) IPR057601 (18.9%) IPR008969 (18.6%)" "TonB-dependent receptor-like (18.9%) TonB-dependent transporter Oar-like, beta-barrel domain (18.9%) Carboxypeptidase-like, regulatory domain superfamily (18.6%)" SHSCGLEAALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.8%) GO:0006811 (3.2%)" GO:0009279 (50%) "iron ion transport (46.8%) monoatomic ion transport (3.2%)" cell outer membrane (50%) "IPR000531 (25.6%) IPR039426 (25.6%) IPR012910 (24.8%)" "TonB-dependent receptor-like, beta-barrel (25.6%) TonB-dependent receptor-like (25.6%) TonB-dependent receptor, plug domain (24.8%)" VMGEALENLYYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006364 (20%) GO:0032259 (20%)" GO:0005737 (20%) "GO:0003723 (20%) GO:0008168 (20%)" "rRNA processing (20%) methylation (20%)" cytoplasm (20%) "RNA binding (20%) methyltransferase activity (20%)" "IPR002478 (16.7%) IPR015947 (16.7%) IPR019614 (16.7%)" "PUA domain (16.7%) PUA-like superfamily (16.7%) S-adenosylmethionine-dependent methyltransferase (16.7%)" SVVTAALAK root "GO:0009279 (86.2%) GO:0005886 (6.9%)" GO:0022857 (6.9%) "cell outer membrane (86.2%) plasma membrane (6.9%)" transmembrane transporter activity (6.9%) "IPR012910 (12.9%) IPR039426 (12.9%) IPR023996 (12.4%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent receptor-like (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.4%)" GGEKEAWEFLDHLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.2%) IPR006235 (17.2%) IPR054542 (17.2%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.2%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.2%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (17.2%)" GLNCSYAVYQDASGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.86 (93.5%) 1.1.1.- (6.5%)" "ketol-acid reductoisomerase (NADP(+)) (93.5%) With NAD(+) or NADP(+) as acceptor (6.5%)" "GO:0009097 (22%) GO:0009099 (22%)" "GO:0004455 (22%) GO:0046872 (21.3%) GO:0016853 (12.6%)" "isoleucine biosynthetic process (22%) L-valine biosynthetic process (22%)" "ketol-acid reductoisomerase activity (22%) metal ion binding (21.3%) isomerase activity (12.6%)" "IPR013116 (17.1%) IPR036291 (17.1%) IPR000506 (16.5%)" "Ketol-acid reductoisomerase, N-terminal (17.1%) NAD(P)-binding domain superfamily (17.1%) Ketol-acid reductoisomerase, C-terminal (16.5%)" SMLNLSGQWVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LVSATGTYTGADNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.7%) GO:0005737 (48.7%)" GO:0016787 (2.6%) "extracellular region (48.7%) cytoplasm (48.7%)" hydrolase activity (2.6%) "IPR050708 (17.2%) IPR022385 (16.3%) IPR006530 (15.8%)" "Type VI secretion system VgrG/RHS (17.2%) Rhs repeat-associated core (16.3%) YD repeat (15.8%)" VTCDLNHPLAGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0042026 (33.3%) GO:0005737 (33.3%) GO:0003755 (33.3%) protein refolding (33.3%) cytoplasm (33.3%) peptidyl-prolyl cis-trans isomerase activity (33.3%) "IPR001179 (33.3%) IPR046357 (33.3%) IPR048261 (33.3%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (33.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (33.3%) PPIase chaperone SlpA/SlyD-like, insertion domain superfamily (33.3%)" YGDDMVDLVR root GO:0016020 (50%) GO:0016301 (50%) membrane (50%) kinase activity (50%) "IPR024299 (23.8%) IPR035376 (23.8%) IPR038143 (23.8%)" "NigD-like N-terminal OB domain (23.8%) NigD-like, C-terminal domain (23.8%) NigD-like, C-terminal domain superfamily (23.8%)" LMSYDEYLYDEALKEQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.2%) IPR003593 (20.2%) IPR032781 (20.2%)" "ABC transporter-like, ATP-binding domain (20.2%) AAA+ ATPase domain (20.2%) ABC-transporter extension domain (20.2%)" TLWVMNQGLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.7%) GO:0005829 (25.7%) "GO:0008733 (25.7%) GO:0030145 (23%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.7%) cytosol (25.7%) "L-arabinose isomerase activity (25.7%) manganese ion binding (23%)" "IPR003762 (15.1%) IPR024664 (15.1%) IPR055390 (15.1%)" "L-arabinose isomerase (15.1%) L-arabinose isomerase, C-terminal (15.1%) L-arabinose isomerase, central domain (15.1%)" VKPELSLSQLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" YFLSGGYTGENGVLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" GLNNNVNLLNAALNVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0015562 (50%) plasma membrane (50%) efflux transmembrane transporter activity (50%) "IPR003423 (33.3%) IPR010131 (33.3%) IPR050737 (33.3%)" "Outer membrane efflux protein (33.3%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (33.3%) Unknown (33.3%)" DNLMMVEGEMK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (13.9%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (13.9%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR012162 (8.1%) IPR015847 (8.1%) IPR001247 (8%)" "Polyribonucleotide nucleotidyltransferase (8.1%) Exoribonuclease, phosphorolytic domain 2 (8.1%) Exoribonuclease, phosphorolytic domain 1 (8%)" FGLSQLHQLR root "5.6.2.4 (66.6%) 3.6.4.- (16.9%) 3.6.4.12 (16.1%)" "DNA 3'-5' helicase (66.6%) Acting on ATP; involved in cellular and subcellular movement (16.9%) DNA helicase (16.1%)" "GO:0006281 (13.8%) GO:0006310 (11%) GO:0000716 (2.7%)" "GO:0005737 (3.6%) GO:0016020 (0%) GO:0005739 (0%)" "GO:0003678 (16.5%) GO:0005524 (16.3%) GO:0003677 (12.6%)" "DNA repair (13.8%) DNA recombination (11%) transcription-coupled nucleotide-excision repair, DNA damage recognition (2.7%)" "cytoplasm (3.6%) membrane (0%) mitochondrion (0%)" "DNA helicase activity (16.5%) ATP binding (16.3%) DNA binding (12.6%)" "IPR001650 (11%) IPR047112 (11%) IPR027417 (11%)" "Helicase, C-terminal domain-like (11%) ATP-dependent DNA helicase RecG/Transcription-repair-coupling factor (11%) P-loop containing nucleoside triphosphate hydrolase (11%)" LTALFQPHLYTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.2.8 (100%) UDP-N-acetylmuramate--L-alanine ligase (100%) "GO:0009252 (13.2%) GO:0008360 (13%) GO:0051301 (13%)" "GO:0005737 (12.8%) GO:0016020 (7.7%)" "GO:0005524 (13.5%) GO:0008763 (13%) GO:0016881 (0.6%)" "peptidoglycan biosynthetic process (13.2%) regulation of cell shape (13%) cell division (13%)" "cytoplasm (12.8%) membrane (7.7%)" "ATP binding (13.5%) UDP-N-acetylmuramate-L-alanine ligase activity (13%) acid-amino acid ligase activity (0.6%)" "IPR036615 (14.6%) IPR050061 (14.6%) IPR004101 (14.5%)" "Mur ligase, C-terminal domain superfamily (14.6%) Peptidoglycan biosynthesis MurCDEF (14.6%) Mur ligase, C-terminal (14.5%)" KFGAPQLTK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.2%) GO:0005737 (16.1%) "GO:0005524 (17.2%) GO:0140662 (17.2%) GO:0016853 (16.2%)" protein refolding (17.2%) cytoplasm (16.1%) "ATP binding (17.2%) ATP-dependent protein folding chaperone (17.2%) isomerase activity (16.2%)" "IPR001844 (16.9%) IPR002423 (16.9%) IPR027413 (16.7%)" "Chaperonin Cpn60/GroEL (16.9%) Chaperonin Cpn60/GroEL/TCP-1 family (16.9%) GroEL-like equatorial domain superfamily (16.7%)" ALTCCMVLANR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (32.2%) GO:0005829 (32.2%) "GO:0004731 (32.2%) GO:0004850 (3.3%)" purine nucleoside catabolic process (32.2%) cytosol (32.2%) "purine-nucleoside phosphorylase activity (32.2%) uridine phosphorylase activity (3.3%)" "IPR000845 (51%) IPR035994 (49%)" "Nucleoside phosphorylase domain (51%) Nucleoside phosphorylase superfamily (49%)" DNVLLNEVAQGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" NAVTELFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (83.3%) GO:0016740 (16.7%)" "glycosyltransferase activity (83.3%) transferase activity (16.7%)" "IPR000836 (25.6%) IPR017932 (25.6%) IPR029055 (24.4%)" "Phosphoribosyltransferase domain (25.6%) Glutamine amidotransferase type 2 domain (25.6%) Nucleophile aminohydrolases, N-terminal (24.4%)" DHVDYYVPLYMNEFAGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.6%) IPR013148 (14.6%) IPR013189 (14.6%)" "Glycoside hydrolase, family 32 (14.6%) Glycosyl hydrolase family 32, N-terminal (14.6%) Glycosyl hydrolase family 32, C-terminal (14.6%)" WGLALDPELGSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000917 (14%) GO:0043093 (14%) GO:0051258 (14%)" "GO:0005737 (14%) GO:0032153 (14%)" "GO:0005525 (15.1%) GO:0003924 (14%)" "division septum assembly (14%) FtsZ-dependent cytokinesis (14%) protein polymerization (14%)" "cytoplasm (14%) cell division site (14%)" "GTP binding (15.1%) GTPase activity (14%)" "IPR024757 (12.3%) IPR000158 (11.4%) IPR003008 (11.4%)" "Cell division protein FtsZ, C-terminal (12.3%) Cell division protein FtsZ (11.4%) Tubulin/FtsZ, GTPase domain (11.4%)" FTLFTTR root "6.1.1.4 (99.4%) 2.3.2.26 (0.2%) 2.7.13.3 (0.2%)" "leucine--tRNA ligase (99.4%) HECT-type E3 ubiquitin transferase (0.2%) histidine kinase (0.2%)" "GO:0006429 (18.2%) GO:0045333 (0.4%) GO:0045492 (0.2%)" "GO:0005829 (18.3%) GO:0016020 (0.9%) GO:0005739 (0.5%)" "GO:0005524 (18.6%) GO:0002161 (18.3%) GO:0004823 (18.3%)" "leucyl-tRNA aminoacylation (18.2%) cellular respiration (0.4%) xylan biosynthetic process (0.2%)" "cytosol (18.3%) membrane (0.9%) mitochondrion (0.5%)" "ATP binding (18.6%) aminoacyl-tRNA deacylase activity (18.3%) leucine-tRNA ligase activity (18.3%)" "IPR002302 (11.6%) IPR025709 (11.6%) IPR009008 (11.6%)" "Leucine-tRNA ligase (11.6%) Leucyl-tRNA synthetase, editing domain (11.6%) Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain (11.6%)" KYSQFLSQQQLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EYMVDLYSHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (18.3%) GO:0006096 (11.3%) GO:0030388 (11.3%)" "GO:0008270 (29.6%) GO:0016832 (16.9%) GO:0004332 (12.7%)" "carbohydrate metabolic process (18.3%) glycolytic process (11.3%) fructose 1,6-bisphosphate metabolic process (11.3%)" "zinc ion binding (29.6%) aldehyde-lyase activity (16.9%) fructose-bisphosphate aldolase activity (12.7%)" "IPR000771 (29.6%) IPR013785 (29.6%) IPR050246 (29.6%)" "Fructose-bisphosphate aldolase, class-II (29.6%) Aldolase-type TIM barrel (29.6%) Class II Fructose-bisphosphate Aldolase (29.6%)" TFGTMHLLNTQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.1%) "GO:0004470 (16.8%) GO:0016616 (16.8%) GO:0016746 (16.8%)" malate metabolic process (16.1%) "malic enzyme activity (16.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.8%) acyltransferase activity (16.8%)" "IPR002505 (9.3%) IPR012301 (9.3%) IPR012302 (9.3%)" "Phosphate acetyl/butaryl transferase (9.3%) Malic enzyme, N-terminal domain (9.3%) Malic enzyme, NAD-binding (9.3%)" DMAGLGQPAFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.4.1.1 (60%) 2.1.3.1 (40%)" "pyruvate carboxylase (60%) methylmalonyl-CoA carboxytransferase (40%)" GO:0006094 (32.9%) GO:0005737 (32.9%) "GO:0004736 (32.9%) GO:0047154 (1.3%)" gluconeogenesis (32.9%) cytoplasm (32.9%) "pyruvate carboxylase activity (32.9%) methylmalonyl-CoA carboxytransferase activity (1.3%)" "IPR000891 (21.2%) IPR003379 (21.2%) IPR055268 (21.2%)" "Pyruvate carboxyltransferase (21.2%) Carboxylase, conserved domain (21.2%) Pyruvate carboxylase-like (21.2%)" NNFTDNFNYPFPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" LGEDNEVLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (34%) IPR020845 (34%) IPR042099 (31.9%)" "AMP-dependent synthetase/ligase domain (34%) AMP-binding, conserved site (34%) ANL, N-terminal domain (31.9%)" LNYLSAMMHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" TYDLSEMFVANK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (24.1%) GO:0009636 (17.2%) GO:0043418 (17.2%)" GO:0005737 (17.2%) GO:0070005 (24.1%) "proteolysis (24.1%) response to toxic substance (17.2%) homocysteine catabolic process (17.2%)" cytoplasm (17.2%) cysteine-type aminopeptidase activity (24.1%) "IPR000169 (32.6%) IPR004134 (32.6%) IPR038765 (31.4%)" "Cysteine peptidase, cysteine active site (32.6%) Peptidase C1B, bleomycin hydrolase (32.6%) Papain-like cysteine peptidase superfamily (31.4%)" AVEGNDFTVGVEEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000028 (33.3%) GO:0006412 (33.3%)" GO:0005829 (33.3%) "ribosomal small subunit assembly (33.3%) translation (33.3%)" cytosol (33.3%) "IPR003728 (34.8%) IPR028989 (34.8%) IPR035956 (30.4%)" "Ribosome maturation factor RimP (34.8%) Ribosome maturation factor RimP, N-terminal (34.8%) RimP, N-terminal domain superfamily (30.4%)" LDLTPFLQFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (9.3%) IPR006103 (9.3%) IPR006104 (9.3%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.3%) Glycoside hydrolase family 2, catalytic domain (9.3%) Glycosyl hydrolases family 2, sugar binding domain (9.3%)" LQFTPDLLPADVVGTQLYSQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.2%) IPR041628 (25.2%) IPR050764 (25.2%)" "ATPase, AAA-3 (25.2%) ChlI/MoxR, AAA lid domain (25.2%) CbbQ/NirQ/NorQ/GpvN (25.2%)" LVATLLENNQTPEGLRVPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.11 (100%) serine--tRNA ligase (100%) GO:0006434 (25%) GO:0005737 (25%) "GO:0004828 (25%) GO:0005524 (25%)" seryl-tRNA aminoacylation (25%) cytoplasm (25%) "serine-tRNA ligase activity (25%) ATP binding (25%)" "IPR002314 (14.6%) IPR002317 (14.6%) IPR006195 (14.6%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (14.6%) Serine-tRNA ligase, type1 (14.6%) Aminoacyl-tRNA synthetase, class II (14.6%)" VGDLLDNFEEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" FASDFFR root "6.1.1.10 (94.8%) 1.13.12.19 (1.3%) 1.14.20.7 (1.3%)" "methionine--tRNA ligase (94.8%) 2-oxoglutarate dioxygenase (ethylene-forming) (1.3%) 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinateforming) (1.3%)" "GO:0006431 (14.5%) GO:0015031 (1.4%) GO:0006303 (0.2%)" "GO:0005829 (14.7%) GO:0016020 (1.4%) GO:0005634 (0.4%)" "GO:0005524 (16.5%) GO:0004825 (14.5%) GO:0046872 (14.5%)" "methionyl-tRNA aminoacylation (14.5%) protein transport (1.4%) double-strand break repair via nonhomologous end joining (0.2%)" "cytosol (14.7%) membrane (1.4%) nucleus (0.4%)" "ATP binding (16.5%) methionine-tRNA ligase activity (14.5%) metal ion binding (14.5%)" "IPR001412 (7.6%) IPR014729 (7.6%) IPR015413 (7.6%)" "Aminoacyl-tRNA synthetase, class I, conserved site (7.6%) Rossmann-like alpha/beta/alpha sandwich fold (7.6%) Methionyl/Leucyl tRNA synthetase (7.6%)" HVGNVTNPFEMLDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.8%) IPR002301 (12.8%) IPR013155 (12.8%)" "Aminoacyl-tRNA synthetase, class Ia (12.8%) Isoleucine-tRNA ligase (12.8%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.8%)" NFCLLGR root "3.1.13.1 (91.8%) 2.7.13.3 (2%) 2.7.7.7 (2%)" "exoribonuclease II (91.8%) histidine kinase (2%) DNA-directed DNA polymerase (2%)" "GO:0006402 (18.9%) GO:0042254 (1.3%) GO:0006897 (0.9%)" "GO:0005829 (18.9%) GO:0016020 (2.1%) GO:0005576 (0.9%)" "GO:0003723 (18.9%) GO:0008859 (18.9%) GO:0005525 (1.3%)" "mRNA catabolic process (18.9%) ribosome biogenesis (1.3%) endocytosis (0.9%)" "cytosol (18.9%) membrane (2.1%) extracellular region (0.9%)" "RNA binding (18.9%) exoribonuclease II activity (18.9%) GTP binding (1.3%)" "IPR001900 (9.7%) IPR003029 (9.7%) IPR004476 (9.7%)" "Ribonuclease II/R (9.7%) S1 domain (9.7%) Ribonuclease II/ribonuclease R (9.7%)" MPGSLEALFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.1%) IPR011990 (32.4%) IPR012944 (32.4%)" "SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (32.4%) RagB/SusD domain (32.4%)" YEDFNLDNVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (43.4%) "GO:0004650 (43.4%) GO:0004557 (13.3%)" carbohydrate metabolic process (43.4%) "polygalacturonase activity (43.4%) alpha-galactosidase activity (13.3%)" "IPR000743 (12.9%) IPR006626 (12.9%) IPR010905 (12.9%)" "Glycoside hydrolase, family 28 (12.9%) Parallel beta-helix repeat (12.9%) Glycosyl hydrolase, family 88 (12.9%)" LQSGDQVELLTSK Pseudomonadati Bacteria Pseudomonadati "3.1.7.2 (52.6%) 2.7.6.5 (47.4%)" "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (52.6%) GTP diphosphokinase (47.4%)" "GO:0015969 (36.7%) GO:0015949 (0.1%) GO:0042594 (0.1%)" GO:0005886 (36.5%) "GO:0016787 (10.8%) GO:0016301 (9.4%) GO:0008893 (3.4%)" "guanosine tetraphosphate metabolic process (36.7%) nucleobase-containing small molecule interconversion (0.1%) response to starvation (0.1%)" plasma membrane (36.5%) "hydrolase activity (10.8%) kinase activity (9.4%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (3.4%)" "IPR004095 (9.1%) IPR033655 (9.1%) IPR007685 (9.1%)" "TGS (9.1%) RelA/SpoT, TGS domain (9.1%) RelA/SpoT (9.1%)" LVVEFMTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (50.7%) IPR023614 (49.3%)" "Phosphate-selective porin O/P (50.7%) Porin domain superfamily (49.3%)" QGLAFFVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (2.8%) "GO:0016787 (80.6%) GO:0046555 (13.9%) GO:0016798 (2.8%)" xylan catabolic process (2.8%) "hydrolase activity (80.6%) acetylxylan esterase activity (13.9%) hydrolase activity, acting on glycosyl bonds (2.8%)" "IPR013094 (29.3%) IPR050300 (29.3%) IPR029058 (28.4%)" "Alpha/beta hydrolase fold-3 (29.3%) GDXG lipolytic enzyme (29.3%) Alpha/Beta hydrolase fold (28.4%)" QNSTDSYMNVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" KMELDQYQQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (20%) GO:0005886 (20%) "GO:0003723 (20%) GO:0004521 (20%) GO:0016787 (20%)" mRNA catabolic process (20%) plasma membrane (20%) "RNA binding (20%) RNA endonuclease activity (20%) hydrolase activity (20%)" "IPR003607 (12.8%) IPR004087 (12.8%) IPR004088 (12.8%)" "HD/PDEase domain (12.8%) K Homology domain (12.8%) K Homology domain, type 1 (12.8%)" NPTTYLTACPLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TLSQMYVNPLDPTQTAHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (27.6%) GO:0009279 (37.9%) GO:0015344 (34.5%) siderophore transmembrane transport (27.6%) cell outer membrane (37.9%) siderophore uptake transmembrane transporter activity (34.5%) "IPR036942 (52.4%) IPR039426 (47.6%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (52.4%) TonB-dependent receptor-like (47.6%)" YYYGLGNLYGASK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR025665 (73%) IPR011250 (27%)" "Outer membrane protein, beta-barrel domain 2 (73%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (27%)" LPDAVGLPEEQLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.13 (100%) fructose-bisphosphate aldolase (100%) "GO:0005975 (18.3%) GO:0006096 (11.3%) GO:0030388 (11.3%)" "GO:0008270 (29.6%) GO:0016832 (16.9%) GO:0004332 (12.7%)" "carbohydrate metabolic process (18.3%) glycolytic process (11.3%) fructose 1,6-bisphosphate metabolic process (11.3%)" "zinc ion binding (29.6%) aldehyde-lyase activity (16.9%) fructose-bisphosphate aldolase activity (12.7%)" "IPR000771 (29.6%) IPR013785 (29.6%) IPR050246 (29.6%)" "Fructose-bisphosphate aldolase, class-II (29.6%) Aldolase-type TIM barrel (29.6%) Class II Fructose-bisphosphate Aldolase (29.6%)" LNPNALMLGFCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (88%) 2.4.1.8 (12%)" "glycogen phosphorylase (88%) maltose phosphorylase (12%)" GO:0005975 (33.1%) "GO:0030170 (33.1%) GO:0008184 (32.8%) GO:0050082 (0.8%)" carbohydrate metabolic process (33.1%) "pyridoxal phosphate binding (33.1%) glycogen phosphorylase activity (32.8%) maltose phosphorylase activity (0.8%)" "IPR011834 (25.1%) IPR052182 (25.1%) IPR000811 (24.9%)" "Alpha-glucan phosphorylase (25.1%) Glycogen_Maltodextrin_Phosphorylase (25.1%) Glycosyl transferase, family 35 (24.9%)" ALFDVYCEGENGEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071973 (33.3%) GO:0009288 (33.3%) GO:0003774 (33.3%) bacterial-type flagellum-dependent cell motility (33.3%) bacterial-type flagellum (33.3%) cytoskeletal motor activity (33.3%) "IPR010106 (99.3%) IPR000563 (0.7%)" "Recombination-promoting nuclease RpnA (99.3%) Flagellar assembly protein FliH (0.7%)" AQFEQLAHNLLQACLVPCQNAVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (33.9%) GO:0140662 (33.9%) GO:0051082 (32.3%)" "ATP binding (33.9%) ATP-dependent protein folding chaperone (33.9%) unfolded protein binding (32.3%)" "IPR013126 (17.1%) IPR018181 (17.1%) IPR043129 (17.1%)" "Heat shock protein 70 family (17.1%) Heat shock protein 70, conserved site (17.1%) ATPase, nucleotide binding domain (17.1%)" VLLDYPTLEEEKLLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.3%) IPR027417 (25.3%) IPR050764 (25.3%)" "ATPase, AAA-3 (25.3%) P-loop containing nucleoside triphosphate hydrolase (25.3%) CbbQ/NirQ/NorQ/GpvN (25.3%)" MNEPAVALGYLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) GO:0016020 (0.5%) "GO:0051536 (49.5%) GO:0016491 (45.4%) GO:0004355 (4.6%)" membrane (0.5%) "iron-sulfur cluster binding (49.5%) oxidoreductase activity (45.4%) glutamate synthase (NADPH) activity (4.6%)" "IPR017927 (10.7%) IPR019480 (10.7%) IPR023753 (10.7%)" "FAD-binding domain, ferredoxin reductase-type (10.7%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (10.7%) FAD/NAD(P)-binding domain (10.7%)" TFALLSHPDAGK root "GO:0006449 (15.5%) GO:0006415 (0%) GO:0000160 (0%)" "GO:0005829 (16%) GO:0016020 (0%) GO:0000428 (0%)" "GO:0003924 (16%) GO:0016150 (16%) GO:0005525 (16%)" "regulation of translational termination (15.5%) translational termination (0%) phosphorelay signal transduction system (0%)" "cytosol (16%) membrane (0%) DNA-directed RNA polymerase complex (0%)" "GTPase activity (16%) translation release factor activity, codon nonspecific (16%) GTP binding (16%)" "IPR004548 (9.2%) IPR000795 (9.2%) IPR027417 (9.2%)" "Peptide chain release factor 3 (9.2%) Translational (tr)-type GTP-binding domain (9.2%) P-loop containing nucleoside triphosphate hydrolase (9.2%)" LMVEMPGLSQPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" RVLPSDLR root "5.4.99.45 (40%) 5.4.99.12 (20%) 2.3.2.31 (10%)" "tRNA pseudouridine(38/39) synthase (40%) tRNA pseudouridine(38-40) synthase (20%) RBR-type E3 ubiquitin transferase (10%)" "GO:0031119 (9.6%) GO:1990481 (9.5%) GO:0006605 (5.7%)" "GO:0005634 (9.5%) GO:0005737 (9.5%) GO:0005886 (5.9%)" "GO:0003723 (9.6%) GO:0009982 (9.5%) GO:0015450 (5.9%)" "tRNA pseudouridine synthesis (9.6%) mRNA pseudouridine synthesis (9.5%) protein targeting (5.7%)" "nucleus (9.5%) cytoplasm (9.5%) plasma membrane (5.9%)" "RNA binding (9.6%) pseudouridine synthase activity (9.5%) protein-transporting ATPase activity (5.9%)" "IPR001406 (7.6%) IPR020094 (7.6%) IPR020095 (7.6%)" "Pseudouridine synthase I, TruA (7.6%) Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal (7.6%) Pseudouridine synthase I, TruA, C-terminal (7.6%)" FSVTDMR root "1.-.-.- (25%) 2.7.1.130 (25%) 2.7.13.3 (25%)" "Oxidoreductases (25%) tetraacyldisaccharide 4'-kinase (25%) histidine kinase (25%)" "GO:0000462 (4.1%) GO:0006826 (4.1%) GO:0045943 (4.1%)" "GO:0009279 (33.3%) GO:0030686 (4.1%) GO:0032040 (4.1%)" "GO:0030515 (4.1%) GO:0015344 (2.4%) GO:0000166 (1.6%)" "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (4.1%) iron ion transport (4.1%) positive regulation of transcription by RNA polymerase I (4.1%)" "cell outer membrane (33.3%) 90S preribosome (4.1%) small-subunit processome (4.1%)" "snoRNA binding (4.1%) siderophore uptake transmembrane transporter activity (2.4%) nucleotide binding (1.6%)" "IPR012910 (10.4%) IPR023997 (10.4%) IPR039426 (10.4%)" "TonB-dependent receptor, plug domain (10.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (10.4%) TonB-dependent receptor-like (10.4%)" FGPQTDEHDYQFK root GO:0032790 (20.1%) "GO:0016020 (20.1%) GO:0005829 (19.9%)" "GO:0043022 (20.1%) GO:0003743 (19.9%)" ribosome disassembly (20.1%) "membrane (20.1%) cytosol (19.9%)" "ribosome binding (20.1%) translation initiation factor activity (19.9%)" "IPR001288 (16.9%) IPR019815 (16.9%) IPR019814 (16.7%)" "Translation initiation factor 3 (16.9%) Translation initiation factor 3, C-terminal (16.9%) Translation initiation factor 3, N-terminal (16.7%)" YANSHNVYNYATQSAPFLYVGDGSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (85.7%) GO:0015344 (14.3%) cell outer membrane (85.7%) siderophore uptake transmembrane transporter activity (14.3%) "IPR036942 (85.7%) IPR039426 (14.3%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (85.7%) TonB-dependent receptor-like (14.3%)" VEFTFLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (25%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (25%)" "IPR001900 (12.4%) IPR003029 (12.4%) IPR004476 (12.4%)" "Ribonuclease II/R (12.4%) S1 domain (12.4%) Ribonuclease II/ribonuclease R (12.4%)" SAFGLNAR root "1.11.1.7 (50%) 3.2.1.2 (33.3%) 3.2.1.- (16.7%)" "peroxidase (50%) beta-amylase (33.3%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (16.7%)" "GO:0006979 (6.8%) GO:0042744 (6.8%) GO:0000272 (4.5%)" "GO:0009279 (27.3%) GO:0005576 (6.8%) GO:0016020 (6.8%)" "GO:0020037 (6.8%) GO:0046872 (6.8%) GO:0140825 (6.8%)" "response to oxidative stress (6.8%) hydrogen peroxide catabolic process (6.8%) polysaccharide catabolic process (4.5%)" "cell outer membrane (27.3%) extracellular region (6.8%) membrane (6.8%)" "heme binding (6.8%) metal ion binding (6.8%) lactoperoxidase activity (6.8%)" "IPR008969 (10%) IPR012910 (10%) IPR023996 (10%)" "Carboxypeptidase-like, regulatory domain superfamily (10%) TonB-dependent receptor, plug domain (10%) TonB-dependent outer membrane protein, SusC/RagA (10%)" CFNLDGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) EDGTGALEYFYGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49%) GO:0005737 (49%)" GO:0016787 (2%) "extracellular region (49%) cytoplasm (49%)" hydrolase activity (2%) "IPR050708 (17.2%) IPR006530 (16.4%) IPR031325 (16%)" "Type VI secretion system VgrG/RHS (17.2%) YD repeat (16.4%) RHS repeat (16%)" KLNHNVTPLENPSELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001854 (33.3%) IPR018254 (33.3%) IPR036049 (33.3%)" "Large ribosomal subunit protein uL29 (33.3%) Large ribosomal subunit protein uL29, conserved site (33.3%) Large ribosomal subunit protein uL29 superfamily (33.3%)" YEATAELSGGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.5%) IPR023996 (34.5%) IPR037066 (30.9%)" "TonB-dependent receptor, plug domain (34.5%) TonB-dependent outer membrane protein, SusC/RagA (34.5%) TonB-dependent receptor, plug domain superfamily (30.9%)" KLGVDMVDEHYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" GDAYCGMLNCSYNLGMR Bacteria Bacteria "GO:0006004 (28.7%) GO:0005996 (4.6%)" GO:0005737 (33.3%) "GO:0008736 (28.7%) GO:0016861 (4.6%)" "fucose metabolic process (28.7%) monosaccharide metabolic process (4.6%)" cytoplasm (33.3%) "L-fucose isomerase activity (28.7%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (4.6%)" "IPR009015 (52.8%) IPR015888 (47.2%)" "L-fucose isomerase, N-terminal/central domain superfamily (52.8%) L-fucose isomerase, C-terminal (47.2%)" LDSYDQVFLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" LGDVMNAFR Pseudomonadati Bacteria Pseudomonadati 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) "GO:0005829 (16.7%) GO:0016020 (0.2%)" "GO:0004818 (16.7%) GO:0005524 (16.7%) GO:0008270 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) "cytosol (16.7%) membrane (0.2%)" "glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%) zinc ion binding (16.7%)" "IPR004527 (10%) IPR020058 (10%) IPR033910 (10%)" "Glutamate-tRNA ligase, bacterial/mitochondrial (10%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10%) Glutamyl-tRNA synthetase (10%)" AAAELGYPVLLR root "6.3.5.5 (85.4%) 6.3.4.16 (6.3%) 2.1.3.2 (2.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (85.4%) carbamoyl-phosphate synthase (ammonia) (6.3%) aspartate carbamoyltransferase (2.1%)" "GO:0006541 (13.6%) GO:0006526 (13%) GO:0006221 (12.3%)" "GO:0005737 (13.3%) GO:0005951 (0.3%)" "GO:0004088 (13.6%) GO:0005524 (13.6%) GO:0046872 (13.6%)" "glutamine metabolic process (13.6%) L-arginine biosynthetic process (13%) pyrimidine nucleotide biosynthetic process (12.3%)" "cytoplasm (13.3%) carbamoyl-phosphate synthase complex (0.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.6%) ATP binding (13.6%) metal ion binding (13.6%)" "IPR005479 (10%) IPR005480 (10%) IPR011761 (10%)" "Carbamoyl phosphate synthase, ATP-binding domain (10%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%) ATP-grasp fold (10%)" EYGAYQLR root "GO:0055085 (27.5%) GO:0015031 (9%) GO:0015891 (6.6%)" "GO:0098797 (20.1%) GO:0016020 (9%) GO:0030288 (6.6%)" "GO:0031992 (20.1%) GO:0000175 (0.2%) GO:0003723 (0.2%)" "transmembrane transport (27.5%) protein transport (9%) siderophore transport (6.6%)" "plasma membrane protein complex (20.1%) membrane (9%) outer membrane-bounded periplasmic space (6.6%)" "energy transducer activity (20.1%) 3'-5'-RNA exonuclease activity (0.2%) RNA binding (0.2%)" "IPR037682 (42.9%) IPR051045 (31.3%) IPR006260 (14%)" "TonB, C-terminal (42.9%) TonB-dependent transporter energy transducer (31.3%) TonB/TolA, C-terminal (14%)" CVGLPGQTLQLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.2%) IPR019533 (25.2%) IPR019758 (25%)" "Peptidase S26A, signal peptidase I (25.2%) Peptidase S26 (25.2%) Peptidase S26A, signal peptidase I, conserved site (25%)" DYGYDAVK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005975 (1.1%) "GO:0005737 (1.1%) GO:0042995 (1.1%)" "GO:0030246 (48.9%) GO:0016787 (46.8%) GO:0004553 (1.1%)" carbohydrate metabolic process (1.1%) "cytoplasm (1.1%) cell projection (1.1%)" "carbohydrate binding (48.9%) hydrolase activity (46.8%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.1%)" "IPR019563 (14.3%) IPR029483 (14.3%) IPR029486 (14.3%)" "Glycosyl-hydrolase 97, catalytic domain (14.3%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.3%) Glycosyl-hydrolase 97, N-terminal domain (14.3%)" MYGLLSVPVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005976 (50%) GO:0052689 (50%) polysaccharide metabolic process (50%) carboxylic ester hydrolase activity (50%) "IPR008391 (33.9%) IPR039069 (33.9%) IPR029058 (32.1%)" "Acetyl xylan esterase domain (33.9%) Carbohydrate esterase 7 family (33.9%) Alpha/Beta hydrolase fold (32.1%)" FLTYDYDYQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.3%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.3%) "IPR006530 (16.8%) IPR031325 (16.3%) IPR050708 (16.3%)" "YD repeat (16.8%) RHS repeat (16.3%) Type VI secretion system VgrG/RHS (16.3%)" VGGNYAASLR root 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (17.5%) GO:0009098 (17.5%) GO:0009099 (17.5%)" "GO:0004084 (17.7%) GO:0052654 (5.9%) GO:0052655 (5.9%)" "isoleucine biosynthetic process (17.5%) L-leucine biosynthetic process (17.5%) L-valine biosynthetic process (17.5%)" "branched-chain-amino-acid transaminase activity (17.7%) L-leucine-2-oxoglutarate transaminase activity (5.9%) L-valine-2-oxoglutarate transaminase activity (5.9%)" "IPR001544 (16.6%) IPR005786 (16.6%) IPR033939 (16.6%)" "Aminotransferase class IV (16.6%) Branched-chain amino acid aminotransferase II (16.6%) Branched-chain aminotransferase (16.6%)" SEYSQYAAEPLTLNFHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0005886 (11.3%) GO:0030288 (11.3%)" "GO:0008955 (11.3%) GO:0004180 (10.7%) GO:0008658 (10.7%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "plasma membrane (11.3%) outer membrane-bounded periplasmic space (11.3%)" "peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.7%) penicillin binding (10.7%)" "IPR001264 (17%) IPR023346 (17%) IPR036950 (17%)" "Glycosyl transferase, family 51 (17%) Lysozyme-like domain superfamily (17%) Penicillin binding protein transglycosylase domain (17%)" TLVEVSPDFYRPTDVVNLWGDPTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.47 (100%) GDP-mannose 4,6-dehydratase (100%) GO:0042351 (33.8%) "GO:0008446 (33.8%) GO:0070401 (32.5%)" 'de novo' GDP-L-fucose biosynthetic process (33.8%) "GDP-mannose 4,6-dehydratase activity (33.8%) NADP+ binding (32.5%)" "IPR006368 (33.8%) IPR016040 (33.8%) IPR036291 (32.5%)" "GDP-mannose 4,6-dehydratase (33.8%) NAD(P)-binding domain (33.8%) NAD(P)-binding domain superfamily (32.5%)" LLVLGADK root "2.3.1.180 (94.1%) 1.8.1.2 (2%) 2.7.1.180 (2%)" "beta-ketoacyl-[acyl-carrier-protein] synthase III (94.1%) assimilatory sulfite reductase (NADPH) (2%) FAD:protein FMN transferase (2%)" "GO:0006633 (12.5%) GO:0044550 (12.4%) GO:0006813 (10.6%)" "GO:0005737 (12.8%) GO:0005886 (4%) GO:0016020 (0.7%)" "GO:0004315 (12.5%) GO:0033818 (12.4%) GO:0008324 (10.6%)" "fatty acid biosynthetic process (12.5%) secondary metabolite biosynthetic process (12.4%) potassium ion transport (10.6%)" "cytoplasm (12.8%) plasma membrane (4%) membrane (0.7%)" "3-oxoacyl-[acyl-carrier-protein] synthase activity (12.5%) beta-ketoacyl-acyl-carrier-protein synthase III activity (12.4%) monoatomic cation transmembrane transporter activity (10.6%)" "IPR013747 (9.5%) IPR013751 (9.5%) IPR016039 (9.5%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (9.5%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (9.5%) Thiolase-like (9.5%)" LALQLPQDVLTAGVTPNPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR033985 (54.5%) IPR011990 (45.5%)" "SusD-like, N-terminal (54.5%) Tetratricopeptide-like helical domain superfamily (45.5%)" VSDEDLHSLGSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.7%) GO:0005737 (24.7%) "GO:0004821 (24.7%) GO:0005524 (24.7%) GO:0004812 (1.1%)" histidyl-tRNA aminoacylation (24.7%) cytoplasm (24.7%) "histidine-tRNA ligase activity (24.7%) ATP binding (24.7%) aminoacyl-tRNA ligase activity (1.1%)" "IPR041715 (12.9%) IPR045864 (12.9%) IPR004154 (12.4%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (12.9%) Anticodon-binding (12.4%)" VAEEAFATGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (33.2%) "GO:0022625 (32.8%) GO:0005840 (0.4%) GO:1990904 (0.4%)" GO:0003735 (33.2%) translation (33.2%) "cytosolic large ribosomal subunit (32.8%) ribosome (0.4%) ribonucleoprotein complex (0.4%)" structural constituent of ribosome (33.2%) "IPR001857 (25.2%) IPR008991 (25.2%) IPR038657 (24.9%)" "Large ribosomal subunit protein bL19 (25.2%) Translation protein SH3-like domain superfamily (25.2%) Large ribosomal subunit protein bL19 superfamily (24.9%)" YMLQATLR root "GO:0019432 (1.8%) GO:0044718 (1.8%)" "GO:0009279 (91.1%) GO:0005886 (1.8%)" "GO:0004144 (1.8%) GO:0015344 (1.8%)" "triglyceride biosynthetic process (1.8%) siderophore transmembrane transport (1.8%)" "cell outer membrane (91.1%) plasma membrane (1.8%)" "diacylglycerol O-acyltransferase activity (1.8%) siderophore uptake transmembrane transporter activity (1.8%)" "IPR023996 (12.9%) IPR036942 (12.9%) IPR039426 (12.6%)" "TonB-dependent outer membrane protein, SusC/RagA (12.9%) TonB-dependent receptor-like, beta-barrel domain superfamily (12.9%) TonB-dependent receptor-like (12.6%)" LMNADQGQFSLEDRDSNTPYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006974 (52.6%) GO:0016020 (47.4%) DNA damage response (52.6%) membrane (47.4%) "IPR007497 (33.9%) IPR052022 (33.9%) IPR016907 (32.2%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.9%) 26 kDa periplasmic antigen-related (33.9%) Uncharacterised conserved protein UCP029033, periplasmic protein (32.2%)" MPLAAGNLFLGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0045493 (50%) GO:0016798 (50%) xylan catabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR025112 (50%) IPR038653 (50%)" "Putative carbohydrate metabolism domain (50%) Putative carbohydrate metabolism domain superfamily (50%)" VSVGYYNQSGLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (6.7%) GO:0009279 (86.7%) GO:0015344 (6.7%) siderophore transmembrane transport (6.7%) cell outer membrane (86.7%) siderophore uptake transmembrane transporter activity (6.7%) "IPR012910 (12.3%) IPR023997 (12.3%) IPR039426 (12.3%)" "TonB-dependent receptor, plug domain (12.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.3%) TonB-dependent receptor-like (12.3%)" DTFDNNLPTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" VTRPQFPANEVNLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (43.2%) "GO:0004650 (43.2%) GO:0004557 (13.5%)" carbohydrate metabolic process (43.2%) "polygalacturonase activity (43.2%) alpha-galactosidase activity (13.5%)" "IPR051801 (20.8%) IPR000743 (20.1%) IPR006626 (20.1%)" "Glycosyl_Hydrolase_28_Enzymes (20.8%) Glycoside hydrolase, family 28 (20.1%) Parallel beta-helix repeat (20.1%)" WQLGTLQVDYNLPER root 6.1.1.3 (100%) threonine--tRNA ligase (100%) "GO:0006435 (16.6%) GO:0006413 (0%) GO:0043039 (0%)" GO:0005737 (16.5%) "GO:0004829 (16.6%) GO:0005524 (16.6%) GO:0046872 (16.5%)" "threonyl-tRNA aminoacylation (16.6%) translational initiation (0%) tRNA aminoacylation (0%)" cytoplasm (16.5%) "threonine-tRNA ligase activity (16.6%) ATP binding (16.6%) metal ion binding (16.5%)" "IPR002314 (7.8%) IPR002320 (7.8%) IPR006195 (7.8%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.8%) Threonine-tRNA ligase, class IIa (7.8%) Aminoacyl-tRNA synthetase, class II (7.8%)" LADLLLMK root "3.2.1.23 (64.3%) 3.2.1.169 (21.4%) 1.-.-.- (3.6%)" "beta-galactosidase (64.3%) protein O-GlcNAcase (21.4%) Oxidoreductases (3.6%)" "GO:0005990 (4.1%) GO:0050982 (3.1%) GO:0016477 (2.8%)" "GO:0016020 (9.8%) GO:0009279 (6.2%) GO:0009341 (4.1%)" "GO:0030246 (7%) GO:0016747 (6.2%) GO:0004565 (4.1%)" "lactose catabolic process (4.1%) detection of mechanical stimulus (3.1%) cell migration (2.8%)" "membrane (9.8%) cell outer membrane (6.2%) beta-galactosidase complex (4.1%)" "carbohydrate binding (7%) acyltransferase activity, transferring groups other than amino-acyl groups (6.2%) beta-galactosidase activity (4.1%)" "IPR012944 (3%) IPR023213 (3%) IPR050317 (3%)" "RagB/SusD domain (3%) Chloramphenicol acetyltransferase-like domain superfamily (3%) Plant and Fungal Acyltransferase (3%)" YGAEALLAR root "2.7.7.7 (62.5%) 3.6.4.- (25%) 2.4.1.80 (12.5%)" "DNA-directed DNA polymerase (62.5%) Acting on ATP; involved in cellular and subcellular movement (25%) ceramide glucosyltransferase (12.5%)" "GO:0006260 (7.5%) GO:0006679 (4.5%) GO:0071897 (1.5%)" "GO:0009279 (14.9%) GO:0016020 (4.5%) GO:0042575 (4.5%)" "GO:0003677 (16.4%) GO:0004386 (9%) GO:0005524 (9%)" "DNA replication (7.5%) glucosylceramide biosynthetic process (4.5%) DNA biosynthetic process (1.5%)" "cell outer membrane (14.9%) membrane (4.5%) DNA polymerase complex (4.5%)" "DNA binding (16.4%) helicase activity (9%) ATP binding (9%)" "IPR012944 (8.3%) IPR033985 (8.3%) IPR011990 (7.5%)" "RagB/SusD domain (8.3%) SusD-like, N-terminal (8.3%) Tetratricopeptide-like helical domain superfamily (7.5%)" LWGGNWLR root "3.4.13.- (72.7%) 2.6.-.- (12.1%) 3.5.1.94 (9.1%)" "Dipeptidases (72.7%) Transferring nitrogenous groups (12.1%) gamma-glutamyl-gamma-aminobutyrate hydrolase (9.1%)" GO:0006508 (46.5%) "GO:0070573 (46.5%) GO:0016740 (5.7%) GO:0016757 (0.7%)" proteolysis (46.5%) "metallodipeptidase activity (46.5%) transferase activity (5.7%) glycosyltransferase activity (0.7%)" "IPR008257 (25.2%) IPR011697 (25%) IPR032466 (24.8%)" "Peptidase M19 (25.2%) Peptidase C26 (25%) Metal-dependent hydrolase (24.8%)" GNVYVGAFDFTYNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR023614 (100%) Porin domain superfamily (100%) VPASPWGNNSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) LSSSNLVVR root "GO:0005975 (28.6%) GO:0006865 (14.3%)" GO:0043190 (14.3%) "GO:0004553 (28.6%) GO:0022857 (14.3%)" "carbohydrate metabolic process (28.6%) amino acid transport (14.3%)" ATP-binding cassette (ABC) transporter complex (14.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (28.6%) transmembrane transporter activity (14.3%)" "IPR043744 (66.7%) IPR000490 (6.7%) IPR017853 (6.7%)" "Domain of unknown function DUF5689 (66.7%) Glycoside hydrolase family 17 (6.7%) Glycoside hydrolase superfamily (6.7%)" EQGAGVLVTSLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (31.7%) IPR015854 (31.7%) IPR027417 (30%)" "ABC transporter-like, ATP-binding domain (31.7%) ABC transporter, lipoprotein release, LolD-like (31.7%) P-loop containing nucleoside triphosphate hydrolase (30%)" YYDLTAVK Bacteria Bacteria "4.2.1.3 (66.7%) 4.2.1.99 (33.3%)" "aconitate hydratase (66.7%) 2-methylisocitrate dehydratase (33.3%)" "GO:0044718 (31.7%) GO:0006099 (0.8%) GO:0019679 (0.8%)" GO:0009279 (31.7%) "GO:0015344 (31.7%) GO:0003723 (0.8%) GO:0003994 (0.8%)" "siderophore transmembrane transport (31.7%) tricarboxylic acid cycle (0.8%) propionate metabolic process, methylcitrate cycle (0.8%)" cell outer membrane (31.7%) "siderophore uptake transmembrane transporter activity (31.7%) RNA binding (0.8%) aconitate hydratase activity (0.8%)" "IPR000531 (19.6%) IPR012910 (19.6%) IPR039426 (19.6%)" "TonB-dependent receptor-like, beta-barrel (19.6%) TonB-dependent receptor, plug domain (19.6%) TonB-dependent receptor-like (19.6%)" GSMFNTPPVVPLYTLMENLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20.2%) GO:0008615 (19.3%)" GO:0005737 (20.2%) "GO:0004648 (20.2%) GO:0030170 (20.2%)" "L-serine biosynthetic process (20.2%) pyridoxine biosynthetic process (19.3%)" cytoplasm (20.2%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20.2%) pyridoxal phosphate binding (20.2%)" "IPR000192 (20.8%) IPR022278 (20.8%) IPR015421 (19.8%)" "Aminotransferase class V domain (20.8%) Phosphoserine aminotransferase (20.8%) Pyridoxal phosphate-dependent transferase, major domain (19.8%)" DGVLADFTACEQMMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000902 (24.7%) GO:0008360 (24.7%)" GO:0005737 (24.7%) "GO:0005524 (24.4%) GO:0016787 (1.4%)" "cell morphogenesis (24.7%) regulation of cell shape (24.7%)" cytoplasm (24.7%) "ATP binding (24.4%) hydrolase activity (1.4%)" "IPR004753 (31.7%) IPR043129 (31.7%) IPR056546 (31.7%)" "Cell shape determining protein MreB (31.7%) ATPase, nucleotide binding domain (31.7%) MreB/MamK-like (31.7%)" LPNALVDVELENLQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (49.2%) GO:0051536 (49.2%) GO:0004355 (1.6%)" "oxidoreductase activity (49.2%) iron-sulfur cluster binding (49.2%) glutamate synthase (NADPH) activity (1.6%)" "IPR017927 (11.3%) IPR019480 (11.3%) IPR023753 (11.3%)" "FAD-binding domain, ferredoxin reductase-type (11.3%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.3%) FAD/NAD(P)-binding domain (11.3%)" QTLTLLDGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.2%) IPR002772 (9.2%) IPR011658 (9.2%)" "Glycoside hydrolase, family 3, N-terminal (9.2%) Glycoside hydrolase family 3 C-terminal domain (9.2%) PA14 domain (9.2%)" LPVEVEYASEFR root 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (13%) GO:0006487 (13%) GO:0006047 (13%)" "GO:0005829 (13%) GO:0005737 (0%) GO:0016020 (0%)" "GO:0004360 (13%) GO:0097367 (13%) GO:0008483 (0%)" "fructose 6-phosphate metabolic process (13%) protein N-linked glycosylation (13%) UDP-N-acetylglucosamine metabolic process (13%)" "cytosol (13%) cytoplasm (0%) membrane (0%)" "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (13%) carbohydrate derivative binding (13%) transaminase activity (0%)" "IPR001347 (12.6%) IPR035466 (12.6%) IPR046348 (12.5%)" "SIS domain (12.6%) GlmS/AgaS, SIS domain 1 (12.6%) SIS domain superfamily (12.5%)" AGMDYFPLLDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR012393 (14.3%) IPR028204 (14.3%) IPR005151 (13.9%)" "Tricorn protease (14.3%) Tricorn protease C1 domain (14.3%) Tail specific protease (13.9%)" DYVMALPLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.3.43 (100%) Transferred entry: 7.4.2.5 (100%) "GO:0006508 (15.6%) GO:0090374 (0.7%)" GO:0005886 (16.7%) "GO:0005524 (17.1%) GO:0016887 (17.1%) GO:0015421 (16.7%)" "proteolysis (15.6%) oligopeptide export from mitochondrion (0.7%)" plasma membrane (16.7%) "ATP binding (17.1%) ATP hydrolysis activity (17.1%) ABC-type oligopeptide transporter activity (16.7%)" "IPR003439 (13.1%) IPR003593 (13.1%) IPR017871 (13.1%)" "ABC transporter-like, ATP-binding domain (13.1%) AAA+ ATPase domain (13.1%) ABC transporter-like, conserved site (13.1%)" KPGVVTLPSGVQYK Pseudomonadati Bacteria Pseudomonadati 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" TVLVSGSGNVAQYTMEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006537 (25.8%) GO:0005829 (25.8%) "GO:0004354 (25.8%) GO:0000166 (22.7%)" glutamate biosynthetic process (25.8%) cytosol (25.8%) "glutamate dehydrogenase (NADP+) activity (25.8%) nucleotide binding (22.7%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" LLGAPPGYVGYDEGGQLTEAVRR root 3.4.21.92 (100%) endopeptidase Clp (100%) "GO:0034605 (19.1%) GO:0042026 (16.6%) GO:0006508 (3.2%)" "GO:0005737 (19.1%) GO:0005829 (0%)" "GO:0005524 (19.2%) GO:0016887 (19.2%) GO:0008233 (3.2%)" "cellular response to heat (19.1%) protein refolding (16.6%) proteolysis (3.2%)" "cytoplasm (19.1%) cytosol (0%)" "ATP binding (19.2%) ATP hydrolysis activity (19.2%) peptidase activity (3.2%)" "IPR003959 (8.6%) IPR050130 (8.6%) IPR001270 (8.6%)" "ATPase, AAA-type, core (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) ClpA/B family (8.6%)" LGGYKGESEQVAADLVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" FELSPLACAYAR Bacteria Bacteria "2.1.2.3 (96%) 3.5.4.10 (4%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (96%) IMP cyclohydrolase (4%)" GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (25.7%) IPR016193 (24.8%) IPR024050 (24.8%)" "Bifunctional purine biosynthesis protein PurH-like (25.7%) Cytidine deaminase-like (24.8%) AICAR transformylase, insert domain superfamily (24.8%)" DMVSSLFR root 3.1.3.16 (100%) protein-serine/threonine phosphatase (100%) GO:0097720 (3.4%) GO:0016020 (93.1%) GO:0033192 (3.4%) calcineurin-mediated signaling (3.4%) membrane (93.1%) calmodulin-dependent protein phosphatase activity (3.4%) "IPR025874 (78.8%) IPR011990 (9.1%) IPR004843 (3%)" "Double zinc ribbon (78.8%) Tetratricopeptide-like helical domain superfamily (9.1%) Calcineurin-like, phosphoesterase domain (3%)" FVQNLTEMLSQSGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20%) IPR003385 (20%) IPR013783 (20%)" "Carbohydrate binding module family 20 (20%) Glycoside hydrolase, family 77 (20%) Immunoglobulin-like fold (20%)" VLALCTPDQEAAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (16.8%) GO:0006417 (16.3%)" GO:0015934 (16.8%) "GO:0003735 (16.8%) GO:0019843 (16.8%) GO:0000049 (16.3%)" "translation (16.8%) regulation of translation (16.3%)" large ribosomal subunit (16.8%) "structural constituent of ribosome (16.8%) rRNA binding (16.8%) tRNA binding (16.3%)" "IPR005878 (17.2%) IPR023673 (17.2%) IPR028364 (17.2%)" "Large ribosomal subunit protein uL1, bacteria (17.2%) Large ribosomal subunit protein uL1, conserved site (17.2%) Ribosomal protein uL1/ribosomal biogenesis protein (17.2%)" DLDLLDAEGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TYTLTPFTLGLLGNATPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR032187 (50%) IPR033408 (50%)" "Outer membrane protein SusF/SusE-like, C-terminal (50%) Outer membrane protein SusF, N-terminal domain (50%)" NLELPQPK root "1.2.3.3 (25%) 1.2.7.1 (25%) 2.7.11.1 (25%)" "pyruvate oxidase (25%) pyruvate synthase (25%) non-specific serine/threonine protein kinase (25%)" "GO:0006979 (13.5%) GO:0022900 (13.5%) GO:0044281 (13.2%)" "GO:0005634 (0.7%) GO:0000139 (0.4%) GO:0005886 (0.4%)" "GO:0005506 (13.5%) GO:0030976 (13.5%) GO:0051539 (13.5%)" "response to oxidative stress (13.5%) electron transport chain (13.5%) small molecule metabolic process (13.2%)" "nucleus (0.7%) Golgi membrane (0.4%) plasma membrane (0.4%)" "iron ion binding (13.5%) thiamine pyrophosphate binding (13.5%) 4 iron, 4 sulfur cluster binding (13.5%)" "IPR002880 (7.1%) IPR011766 (7.1%) IPR011895 (7.1%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.1%) Pyruvate-flavodoxin oxidoreductase (7.1%)" YAELLLNAAEALNEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" DLENNTLELMR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR004154 (11.4%) IPR004499 (11.4%) IPR002314 (11.2%)" "Anticodon-binding (11.4%) Proline-tRNA ligase, class IIa, archaeal-type (11.4%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.2%)" EVESLYNVTVVDVNTLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.8%) "GO:0005840 (20.8%) GO:1990904 (20.8%)" "GO:0003735 (20.8%) GO:0019843 (16.7%)" translation (20.8%) "ribosome (20.8%) ribonucleoprotein complex (20.8%)" "structural constituent of ribosome (20.8%) rRNA binding (16.7%)" "IPR012677 (33.3%) IPR012678 (33.3%) IPR013025 (33.3%)" "Nucleotide-binding alpha-beta plait domain superfamily (33.3%) Ribosomal protein uL23/eL15/eS24 core domain superfamily (33.3%) Large ribosomal subunit protein uL23-like (33.3%)" VPQQYLNFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000028 (33.3%) GO:0006412 (33.3%)" GO:0005829 (33.3%) "ribosomal small subunit assembly (33.3%) translation (33.3%)" cytosol (33.3%) "IPR003728 (28.3%) IPR028989 (28.3%) IPR035956 (27.7%)" "Ribosome maturation factor RimP (28.3%) Ribosome maturation factor RimP, N-terminal (28.3%) RimP, N-terminal domain superfamily (27.7%)" QNVLLLNTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR018392 (34.7%) IPR028082 (32.6%) IPR036779 (32.6%)" "LysM domain (34.7%) Periplasmic binding protein-like I (32.6%) LysM domain superfamily (32.6%)" LTQPVVNFLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.6%) IPR012944 (33.5%) IPR011990 (31.9%)" "SusD-like, N-terminal (34.6%) RagB/SusD domain (33.5%) Tetratricopeptide-like helical domain superfamily (31.9%)" TLTTSNTLNYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" AYGLPYDVVLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR011766 (12.7%) IPR012000 (12.7%) IPR012001 (12.7%)" "Thiamine pyrophosphate enzyme, TPP-binding (12.7%) Thiamine pyrophosphate enzyme, central domain (12.7%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.7%)" AMAGVLVVTTK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (3.5%) GO:0006826 (0.8%)" GO:0009279 (92.1%) GO:0015344 (3.5%) "siderophore transmembrane transport (3.5%) iron ion transport (0.8%)" cell outer membrane (92.1%) siderophore uptake transmembrane transporter activity (3.5%) "IPR023997 (14.4%) IPR012910 (14.4%) IPR037066 (14.4%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (14.4%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent receptor, plug domain superfamily (14.4%)" GYVGDVTGNYNGVTTGQNLEDKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" FTNFTMTK root GO:0005975 (30.3%) GO:0005576 (30.3%) "GO:0004650 (30.3%) GO:0004557 (9.2%)" carbohydrate metabolic process (30.3%) extracellular region (30.3%) "polygalacturonase activity (30.3%) alpha-galactosidase activity (9.2%)" "IPR000743 (28%) IPR011050 (27.1%) IPR012334 (27.1%)" "Glycoside hydrolase, family 28 (28%) Pectin lyase fold/virulence factor (27.1%) Pectin lyase fold (27.1%)" VNWAYQR Bacteria Bacteria GO:0009279 (87.5%) "GO:0003824 (4.2%) GO:0046872 (4.2%) GO:0051539 (4.2%)" cell outer membrane (87.5%) "catalytic activity (4.2%) metal ion binding (4.2%) 4 iron, 4 sulfur cluster binding (4.2%)" "IPR012944 (46.7%) IPR011990 (44.4%) IPR007197 (2.2%)" "RagB/SusD domain (46.7%) Tetratricopeptide-like helical domain superfamily (44.4%) Radical SAM (2.2%)" GSFYDAYSDGAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.2.1.- (80%) 3.2.1.177 (20%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (80%) alpha-D-xyloside xylohydrolase (20%)" GO:0005975 (34.3%) "GO:0004553 (33.3%) GO:0030246 (31.4%) GO:0061634 (1%)" carbohydrate metabolic process (34.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (31.4%) alpha-D-xyloside xylohydrolase (1%)" "IPR000322 (11.4%) IPR025887 (11.4%) IPR033403 (11.4%)" "Glycoside hydrolase family 31, TIM barrel domain (11.4%) Glycoside hydrolase family 31, N-terminal domain (11.4%) Domain of unknown function DUF5110 (11.4%)" NPNLGQNAGWELSDAPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" NVAYPFGYGLSYTTFEFGKPSVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (50%) "GO:0004553 (48.8%) GO:0008422 (1.3%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.8%) beta-glucosidase activity (1.3%)" "IPR002772 (13%) IPR050288 (13%) IPR001764 (12.7%)" "Glycoside hydrolase family 3 C-terminal domain (13%) Cellulose-degrading glycosyl hydrolase 3 (13%) Glycoside hydrolase, family 3, N-terminal (12.7%)" ANAVAPGFLETAMTAQLPEELRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) GO:0006633 (33.3%) "GO:0004316 (30%) GO:0051287 (30%) GO:0016616 (3.3%)" fatty acid biosynthetic process (33.3%) "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (30%) NAD binding (30%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (3.3%)" "IPR002347 (17.9%) IPR020904 (17.9%) IPR011284 (16.1%)" "Short-chain dehydrogenase/reductase SDR (17.9%) Short-chain dehydrogenase/reductase, conserved site (17.9%) 3-oxoacyl-(acyl-carrier-protein) reductase (16.1%)" FEFPCEWGDDLASEHER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.6%) GO:0005737 (19%) "GO:0005524 (20.6%) GO:0003676 (19%) GO:0004816 (19%)" asparaginyl-tRNA aminoacylation (20.6%) cytoplasm (19%) "ATP binding (20.6%) nucleic acid binding (19%) asparagine-tRNA ligase activity (19%)" "IPR004364 (15.3%) IPR006195 (14.7%) IPR045864 (14.7%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (15.3%) Aminoacyl-tRNA synthetase, class II (14.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.7%)" FMAPEPER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) GTANSSAEVEAVMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" YFSDATLK Bacteria Bacteria 4.2.1.51 (100%) prephenate dehydratase (100%) AHLEAVAGLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" NFGLDYGFFNGR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (28.1%) GO:0009279 (71.9%) iron ion transport (28.1%) cell outer membrane (71.9%) "IPR008969 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "Carboxypeptidase-like, regulatory domain superfamily (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" GGDLDNALVLYER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.1.108 (52.7%) 4.2.1.59 (47%) 4.2.1.- (0.3%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (52.7%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (47%) Hydro-lyases (0.3%)" "GO:0009245 (14.5%) GO:0006633 (13.8%)" "GO:0016020 (14.5%) GO:0005737 (14.2%)" "GO:0103117 (14.5%) GO:0046872 (14.3%) GO:0019171 (10.1%)" "lipid A biosynthetic process (14.5%) fatty acid biosynthetic process (13.8%)" "membrane (14.5%) cytoplasm (14.2%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.5%) metal ion binding (14.3%) (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity (10.1%)" "IPR004463 (14.6%) IPR011334 (14.4%) IPR020568 (14.4%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.6%) UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal (14.4%) Ribosomal protein uS5 domain 2-type superfamily (14.4%)" KPGLEQALQQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (34.2%) GO:0140662 (34.2%) GO:0051082 (31.6%)" "ATP binding (34.2%) ATP-dependent protein folding chaperone (34.2%) unfolded protein binding (31.6%)" "IPR013126 (17.1%) IPR029047 (17.1%) IPR029048 (17.1%)" "Heat shock protein 70 family (17.1%) Heat shock protein 70kD, peptide-binding domain superfamily (17.1%) Heat shock protein 70kD, C-terminal domain superfamily (17.1%)" LVAFDLPKEFLGAVLGPGGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" LFGNAFVELKPVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EQLVMALADLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (13%) IPR050220 (13%) IPR005743 (12.7%)" "DNA topoisomerase, type IIA, domain A (13%) Type II DNA Topoisomerases (13%) DNA gyrase, subunit A (12.7%)" SYELWLEGCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (31.8%) IPR012944 (31.8%) IPR033985 (29.4%)" "Tetratricopeptide-like helical domain superfamily (31.8%) RagB/SusD domain (31.8%) SusD-like, N-terminal (29.4%)" YLLFGVR root "2.3.2.26 (25%) 7.1.1.9 (18.8%) 2.7.7.49 (12.5%)" "HECT-type E3 ubiquitin transferase (25%) cytochrome-c oxidase (18.8%) RNA-directed DNA polymerase (12.5%)" "GO:0000209 (2.1%) GO:0006123 (1.6%) GO:0006511 (1.6%)" "GO:0016020 (10.9%) GO:0005886 (3.1%) GO:0005743 (2.1%)" "GO:0004180 (15.6%) GO:0003676 (2.6%) GO:0003677 (2.6%)" "protein polyubiquitination (2.1%) mitochondrial electron transport, cytochrome c to oxygen (1.6%) ubiquitin-dependent protein catabolic process (1.6%)" "membrane (10.9%) plasma membrane (3.1%) mitochondrial inner membrane (2.1%)" "carboxypeptidase activity (15.6%) nucleic acid binding (2.6%) DNA binding (2.6%)" "IPR008969 (11.8%) IPR043741 (11.8%) IPR012337 (2.2%)" "Carboxypeptidase-like, regulatory domain superfamily (11.8%) Family of unknown function DUF5686 (11.8%) Ribonuclease H-like superfamily (2.2%)" LEAAVDALNK Bacteria Bacteria 4.99.1.9 (100%) coproporphyrin ferrochelatase (100%) "GO:0006412 (21.1%) GO:0006783 (5.3%)" "GO:0005840 (21.1%) GO:1990904 (15.8%) GO:0005737 (5.3%)" "GO:0003735 (21.1%) GO:0004325 (5.3%) GO:0046872 (5.3%)" "translation (21.1%) heme biosynthetic process (5.3%)" "ribosome (21.1%) ribonucleoprotein complex (15.8%) cytoplasm (5.3%)" "structural constituent of ribosome (21.1%) ferrochelatase activity (5.3%) metal ion binding (5.3%)" "IPR036049 (28.6%) IPR001854 (21.4%) IPR018254 (21.4%)" "Large ribosomal subunit protein uL29 superfamily (28.6%) Large ribosomal subunit protein uL29 (21.4%) Large ribosomal subunit protein uL29, conserved site (21.4%)" VNQTLESAHQFTEK Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) "IPR003399 (50%) IPR052336 (50%)" "Mce/MlaD (50%) MlaD Inter-membrane Phospholipid Transporter (50%)" AKETNVLNSLSGK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (8.5%) GO:0044718 (6.8%)" GO:0009279 (76.3%) GO:0015344 (8.5%) "iron ion transport (8.5%) siderophore transmembrane transport (6.8%)" cell outer membrane (76.3%) siderophore uptake transmembrane transporter activity (8.5%) "IPR012910 (13.9%) IPR023997 (13.9%) IPR039426 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.9%) TonB-dependent receptor-like (13.9%)" NKEYGAYQLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0055085 (27.9%) GO:0015031 (8.3%) GO:0015891 (7%)" "GO:0098797 (20.1%) GO:0016020 (9.6%) GO:0030288 (7%)" GO:0031992 (20.1%) "transmembrane transport (27.9%) protein transport (8.3%) siderophore transport (7%)" "plasma membrane protein complex (20.1%) membrane (9.6%) outer membrane-bounded periplasmic space (7%)" energy transducer activity (20.1%) "IPR037682 (44.1%) IPR051045 (31.7%) IPR006260 (13.1%)" "TonB, C-terminal (44.1%) TonB-dependent transporter energy transducer (31.7%) TonB/TolA, C-terminal (13.1%)" LRPEFVDK Pseudomonadati Bacteria Pseudomonadati "GO:0009279 (96.2%) GO:0016020 (3.8%)" "cell outer membrane (96.2%) membrane (3.8%)" "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (31.1%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (31.1%)" LGPSAFEQCAGFLR Bacteria Bacteria "GO:0006139 (19.9%) GO:0006412 (19.9%)" "GO:0005737 (19.9%) GO:0005840 (0.6%)" "GO:0003729 (19.9%) GO:0003735 (19.9%)" "nucleobase-containing compound metabolic process (19.9%) translation (19.9%)" "cytoplasm (19.9%) ribosome (0.6%)" "mRNA binding (19.9%) structural constituent of ribosome (19.9%)" "IPR003029 (7.2%) IPR006641 (7.2%) IPR018974 (7.2%)" "S1 domain (7.2%) YqgF/RNase H-like domain (7.2%) Tex-like protein, N-terminal (7.2%)" AGNASMSLVQTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021457 (100%) Protein of unknown function DUF3108 (100%) LAETAMALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (24.1%) GO:0016052 (24.1%) GO:0007165 (1.2%)" "GO:0005737 (24.1%) GO:0016020 (1.2%)" "GO:0004139 (24.1%) GO:0003824 (1.2%)" "deoxyribonucleotide catabolic process (24.1%) carbohydrate catabolic process (24.1%) signal transduction (1.2%)" "cytoplasm (24.1%) membrane (1.2%)" "deoxyribose-phosphate aldolase activity (24.1%) catalytic activity (1.2%)" "IPR002915 (29.9%) IPR011343 (29.9%) IPR013785 (29.9%)" "DeoC/FbaB/LacD aldolase (29.9%) Deoxyribose-phosphate aldolase (29.9%) Aldolase-type TIM barrel (29.9%)" LYGEALGEEALYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" ASHGVLLLTTK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (13.8%) GO:0006826 (3%) GO:0015889 (1%)" GO:0009279 (67.5%) GO:0015344 (14.3%) "siderophore transmembrane transport (13.8%) iron ion transport (3%) cobalamin transport (1%)" cell outer membrane (67.5%) siderophore uptake transmembrane transporter activity (14.3%) "IPR012910 (13.4%) IPR023997 (13.4%) IPR039426 (13.4%)" "TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.4%) TonB-dependent receptor-like (13.4%)" STVATLTGLGAMAGGLGSFLLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (50%) GO:0015134 (50%) membrane (50%) hexuronate transmembrane transporter activity (50%) "IPR011701 (25.4%) IPR020846 (25.4%) IPR050382 (25.4%)" "Major facilitator superfamily (25.4%) Major facilitator superfamily domain (25.4%) Major Facilitator Superfamily Sodium/Anion Cotransporter (25.4%)" VVSPNQTTYVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (20%) "GO:0003924 (20%) GO:0005525 (20%) GO:0043022 (20%)" cytoplasm (20%) "GTPase activity (20%) GTP binding (20%) ribosome binding (20%)" "IPR005225 (12.8%) IPR006073 (12.8%) IPR016496 (12.8%)" "Small GTP-binding domain (12.8%) GTP binding domain (12.8%) GTPase HflX (12.8%)" NLPTYSVSSLFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.99.12 (100%) lipid IVA 3-deoxy-D-manno-octulosonic acid transferase (100%) "GO:0009245 (25.3%) GO:0009244 (24.1%)" GO:0005886 (25.3%) "GO:0016740 (16.5%) GO:0043842 (8.8%)" "lipid A biosynthetic process (25.3%) lipopolysaccharide core region biosynthetic process (24.1%)" plasma membrane (25.3%) "transferase activity (16.5%) Kdo transferase activity (8.8%)" "IPR007507 (33.9%) IPR039901 (33.9%) IPR038107 (32.3%)" "3-deoxy-D-manno-octulosonic-acid transferase, N-terminal (33.9%) 3-deoxy-D-manno-octulosonic acid transferase (33.9%) 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily (32.3%)" KNPMTPGLDYAAYPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (33.3%) GO:0009279 (66.7%) iron ion transport (33.3%) cell outer membrane (66.7%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VTELQEYYFSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.- (100%) Transaminases (100%) "GO:0008483 (50%) GO:0030170 (50%)" "transaminase activity (50%) pyridoxal phosphate binding (50%)" "IPR004838 (17.6%) IPR004839 (17.6%) IPR050881 (17.6%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (17.6%) Aminotransferase, class I/classII, large domain (17.6%) LL-diaminopimelate aminotransferase (17.6%)" TLYFNYLDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NFQNLQNLYLGSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" YLGDLTDDLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VAFDLGLR root "4.1.3.4 (66.7%) 4.1.1.48 (33.3%)" "hydroxymethylglutaryl-CoA lyase (66.7%) indole-3-glycerol-phosphate synthase (33.3%)" "GO:0006412 (19.6%) GO:0006552 (0.2%) GO:0046951 (0.2%)" "GO:0005840 (19.6%) GO:1990904 (19.6%) GO:0005737 (0.1%)" "GO:0003735 (19.6%) GO:0019843 (19.5%) GO:0004419 (0.2%)" "translation (19.6%) L-leucine catabolic process (0.2%) ketone body biosynthetic process (0.2%)" "ribosome (19.6%) ribonucleoprotein complex (19.6%) cytoplasm (0.1%)" "structural constituent of ribosome (19.6%) rRNA binding (19.5%) hydroxymethylglutaryl-CoA lyase activity (0.2%)" "IPR001971 (24%) IPR036967 (24%) IPR018102 (23.9%)" "Small ribosomal subunit protein uS11 (24%) Small ribosomal subunit protein uS11 superfamily (24%) Small ribosomal subunit protein uS11, conserved site (23.9%)" SFYQTNTEQAYHLYCVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.190 (96.4%) 2.1.1.- (3.6%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (96.4%) Methyltransferases (3.6%)" GO:0070475 (50%) GO:0070041 (50%) rRNA base methylation (50%) rRNA (uridine-C5-)-methyltransferase activity (50%) "IPR010280 (17.3%) IPR030390 (17.3%) IPR002792 (16.8%)" "(Uracil-5)-methyltransferase family (17.3%) RNA methyltransferase TrmA, active site (17.3%) TRAM domain (16.8%)" YSDYYLWMNDLPESEKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (50%) GO:0004556 (50%) oligosaccharide catabolic process (50%) alpha-amylase activity (50%) "IPR006047 (26.4%) IPR017853 (25%) IPR045857 (25%)" "Glycosyl hydrolase family 13, catalytic domain (26.4%) Glycoside hydrolase superfamily (25%) Oligo-1,6-glucosidase, domain 2 (25%)" EAEAYPGPSLLLAYAPCLNHGLK Bacteria Bacteria "1.2.7.1 (94.6%) 1.2.7.- (5.1%) 1.2.1.51 (0.3%)" "pyruvate synthase (94.6%) With an iron-sulfur protein as acceptor (5.1%) pyruvate dehydrogenase (NADP(+)) (0.3%)" "GO:0006979 (16.2%) GO:0022900 (15.5%) GO:0044281 (5.6%)" "GO:0005506 (15.5%) GO:0051539 (15.5%) GO:0030976 (15.4%)" "response to oxidative stress (16.2%) electron transport chain (15.5%) small molecule metabolic process (5.6%)" "iron ion binding (15.5%) 4 iron, 4 sulfur cluster binding (15.5%) thiamine pyrophosphate binding (15.4%)" "IPR050722 (8%) IPR029061 (8%) IPR017896 (7.7%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (8%) Thiamin diphosphate-binding fold (8%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (7.7%)" DGFLMGEGAGCLLLEELEHAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.6%) IPR014030 (14.6%) IPR020841 (14.6%)" "Beta-ketoacyl synthase (14.6%) Beta-ketoacyl synthase-like, N-terminal (14.6%) Polyketide synthase, beta-ketoacyl synthase domain (14.6%)" NELLSGYAK root 3.5.1.98 (100%) histone deacetylase (100%) "GO:0032958 (3.4%) GO:0040029 (3.4%)" GO:0000118 (3.4%) "GO:0005524 (20.5%) GO:0016887 (20.5%) GO:0051082 (20.5%)" "inositol phosphate biosynthetic process (3.4%) epigenetic regulation of gene expression (3.4%)" histone deacetylase complex (3.4%) "ATP binding (20.5%) ATP hydrolysis activity (20.5%) unfolded protein binding (20.5%)" "IPR001404 (16.5%) IPR019805 (16.5%) IPR020568 (16.5%)" "Heat shock protein Hsp90 family (16.5%) Heat shock protein Hsp90, conserved site (16.5%) Ribosomal protein uS5 domain 2-type superfamily (16.5%)" FSQAEMDEEVHDSASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.7%) "GO:0042910 (33.7%) GO:0008324 (32.6%)" plasma membrane (33.7%) "xenobiotic transmembrane transporter activity (33.7%) monoatomic cation transmembrane transporter activity (32.6%)" "IPR001036 (34.5%) IPR004763 (33.3%) IPR027463 (32.2%)" "Acriflavin resistance protein (34.5%) Cation efflux system CusA-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (32.2%)" MNLLELSEQELVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004824 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) lysine-tRNA ligase activity (16.7%)" "IPR002313 (12.5%) IPR004364 (12.5%) IPR004365 (12.5%)" "Lysine-tRNA ligase, class II (12.5%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.5%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.5%)" VGDADAQAAVTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (50%) GO:0003746 (50%) cytoplasm (50%) translation elongation factor activity (50%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" LVSNASCTTNCLAPLAK root "1.2.1.- (52.9%) 1.2.1.12 (46.7%) 2.6.99.- (0.2%)" "With NAD(+) or NADP(+) as acceptor (52.9%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (46.7%) Transferring other nitrogenous groups (0.2%)" "GO:0006006 (12.3%) GO:0006096 (10.9%) GO:0006915 (2.6%)" "GO:0005829 (9.8%) GO:0005856 (2.9%) GO:0005634 (2.9%)" "GO:0051287 (15.3%) GO:0004365 (13.7%) GO:0050661 (12.6%)" "glucose metabolic process (12.3%) glycolytic process (10.9%) apoptotic process (2.6%)" "cytosol (9.8%) cytoskeleton (2.9%) nucleus (2.9%)" "NAD binding (15.3%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (13.7%) NADP binding (12.6%)" "IPR020830 (17.6%) IPR020831 (17.6%) IPR020829 (17.5%)" "Glyceraldehyde 3-phosphate dehydrogenase, active site (17.6%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (17.6%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (17.5%)" EGDHVNAGDALFVNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" QGSDPDMAAVNVQNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009636 (23.9%) GO:0005886 (25.8%) "GO:0042910 (25.8%) GO:0015562 (24.5%)" response to toxic substance (23.9%) plasma membrane (25.8%) "xenobiotic transmembrane transporter activity (25.8%) efflux transmembrane transporter activity (24.5%)" "IPR001036 (34.1%) IPR027463 (33.3%) IPR004764 (32.5%)" "Acriflavin resistance protein (34.1%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%) Multidrug resistance protein MdtF-like (32.5%)" NVTAGANPMDLKR root 5.6.1.7 (100%) chaperonin ATPase (100%) "GO:0042026 (20.1%) GO:0009408 (0.1%) GO:0051085 (0%)" "GO:0005737 (11.7%) GO:0009986 (0.1%) GO:0042603 (0.1%)" "GO:0005524 (20.1%) GO:0140662 (20.1%) GO:0016853 (15.8%)" "protein refolding (20.1%) response to heat (0.1%) obsolete chaperone cofactor-dependent protein refolding (0%)" "cytoplasm (11.7%) cell surface (0.1%) capsule (0.1%)" "ATP binding (20.1%) ATP-dependent protein folding chaperone (20.1%) isomerase activity (15.8%)" "IPR001844 (17.9%) IPR002423 (17.9%) IPR027413 (17.8%)" "Chaperonin Cpn60/GroEL (17.9%) Chaperonin Cpn60/GroEL/TCP-1 family (17.9%) GroEL-like equatorial domain superfamily (17.8%)" AAAVEQLCLWGER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (16.7%) "GO:0005737 (16.7%) GO:0005886 (16.7%)" "GO:0003924 (16.7%) GO:0005047 (16.7%) GO:0005525 (16.7%)" SRP-dependent cotranslational protein targeting to membrane (16.7%) "cytoplasm (16.7%) plasma membrane (16.7%)" "GTPase activity (16.7%) signal recognition particle binding (16.7%) GTP binding (16.7%)" "IPR000897 (14.4%) IPR003593 (14.4%) IPR004390 (14.4%)" "Signal recognition particle, SRP54 subunit, GTPase domain (14.4%) AAA+ ATPase domain (14.4%) Signal-recognition particle receptor FtsY (14.4%)" KSDLSGASVSMGEDQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.9%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.9%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YADVLLMK root 3.1.21.3 (100%) type I site-specific deoxyribonuclease (100%) "GO:0006508 (0.2%) GO:0007156 (0.2%) GO:0009307 (0.2%)" "GO:0009279 (97.8%) GO:0030425 (0.2%) GO:0042734 (0.2%)" "GO:0003677 (0.2%) GO:0004252 (0.2%) GO:0004386 (0.2%)" "proteolysis (0.2%) homophilic cell-cell adhesion (0.2%) DNA restriction-modification system (0.2%)" "cell outer membrane (97.8%) dendrite (0.2%) presynaptic membrane (0.2%)" "DNA binding (0.2%) serine-type endopeptidase activity (0.2%) helicase activity (0.2%)" "IPR012944 (33.8%) IPR011990 (33.6%) IPR033985 (31.4%)" "RagB/SusD domain (33.8%) Tetratricopeptide-like helical domain superfamily (33.6%) SusD-like, N-terminal (31.4%)" FYLPEPEDHYNLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.7%) GO:0006164 (0.5%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.5%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR010073 (11.2%) IPR010918 (11.2%) IPR029062 (11.2%)" "Phosphoribosylformylglycinamidine synthase PurL (11.2%) PurM-like, C-terminal domain (11.2%) Class I glutamine amidotransferase-like (11.2%)" DLLAGQLYFFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (33.9%) IPR011990 (33%) IPR012944 (33%)" "SusD-like, N-terminal (33.9%) Tetratricopeptide-like helical domain superfamily (33%) RagB/SusD domain (33%)" KVLSSNLLLNLNEPCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" FNDGDVLTVEPWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.99.1 (100%) Deleted entry (100%) "GO:0009060 (24.3%) GO:0022904 (24.3%)" "GO:0009055 (24.3%) GO:0051537 (24.3%) GO:0016491 (2.7%)" "aerobic respiration (24.3%) respiratory electron transport chain (24.3%)" "electron transfer activity (24.3%) 2 iron, 2 sulfur cluster binding (24.3%) oxidoreductase activity (2.7%)" "IPR006058 (13.8%) IPR009051 (13.8%) IPR012675 (13.8%)" "2Fe-2S ferredoxin, iron-sulphur binding site (13.8%) Alpha-helical ferredoxin (13.8%) Beta-grasp domain superfamily (13.8%)" MVGTNNCYLTSQNHGYAVDAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006207 (16%) GO:0006526 (16%) GO:0006541 (16%)" "GO:0004088 (16%) GO:0005524 (16%) GO:0004359 (4%)" "'de novo' pyrimidine nucleobase biosynthetic process (16%) L-arginine biosynthetic process (16%) glutamine metabolic process (16%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (16%) ATP binding (16%) glutaminase activity (4%)" "IPR002474 (14.3%) IPR006274 (14.3%) IPR017926 (14.3%)" "Carbamoyl-phosphate synthase small subunit, N-terminal domain (14.3%) Carbamoyl-phosphate synthase, small subunit (14.3%) Glutamine amidotransferase (14.3%)" LSNEFAAEQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (50%) IPR024930 (50%)" "Chaperone protein Skp (50%) Skp domain superfamily (50%)" TALLFTTR root "GO:0006952 (17.9%) GO:0051707 (15.4%) GO:0000272 (10.3%)" GO:0005886 (2.6%) "GO:0043531 (20.5%) GO:0004553 (7.7%) GO:0004197 (5.1%)" "defense response (17.9%) response to other organism (15.4%) polysaccharide catabolic process (10.3%)" plasma membrane (2.6%) "ADP binding (20.5%) hydrolase activity, hydrolyzing O-glycosyl compounds (7.7%) cysteine-type endopeptidase activity (5.1%)" "IPR024370 (11.8%) IPR050811 (11.8%) IPR002182 (6.7%)" "PBP domain (11.8%) Phosphate-binding ABC transporter substrate-binding (11.8%) NB-ARC (6.7%)" DAEANAPVSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.4%) IPR002890 (19.4%) IPR051802 (19.4%)" "Alpha-2-macroglobulin (19.4%) Macroglobulin domain (19.4%) Alpha-2-macroglobulin-like (19.4%)" NPLSLDKVEPVEELVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20.2%) GO:0019676 (19.7%)" "GO:0046872 (19.7%) GO:0051538 (19.7%) GO:0015930 (14.6%)" "glutamate biosynthetic process (20.2%) ammonia assimilation cycle (19.7%)" "metal ion binding (19.7%) 3 iron, 4 sulfur cluster binding (19.7%) glutamate synthase activity (14.6%)" "IPR002932 (12.9%) IPR002489 (12.5%) IPR006982 (12.5%)" "Glutamate synthase domain (12.9%) Glutamate synthase, alpha subunit, C-terminal (12.5%) Glutamate synthase, central-N (12.5%)" DNALAMLEQQYTMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" VFLPALDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (25%) "GO:0016788 (25.7%) GO:0046872 (25.7%) GO:0004536 (23.7%)" cytosol (25%) "hydrolase activity, acting on ester bonds (25.7%) metal ion binding (25.7%) DNA nuclease activity (23.7%)" "IPR001130 (25%) IPR018228 (25%) IPR032466 (24.4%)" "3'-5' ssDNA/RNA exonuclease TatD-like (25%) Deoxyribonuclease, TatD-related, conserved site (25%) Metal-dependent hydrolase (24.4%)" YPDLAYLK root "3.2.1.22 (90.2%) 3.5.1.1 (5.9%) 2.3.2.27 (3.9%)" "alpha-galactosidase (90.2%) asparaginase (5.9%) RING-type E3 ubiquitin transferase (3.9%)" "GO:0016052 (20.6%) GO:0006520 (1.4%) GO:0006508 (0.9%)" "GO:0016020 (45%) GO:0030288 (0.9%) GO:0005654 (0.5%)" "GO:0004557 (20.6%) GO:0004067 (1.4%) GO:0004175 (0.9%)" "carbohydrate catabolic process (20.6%) amino acid metabolic process (1.4%) proteolysis (0.9%)" "membrane (45%) outer membrane-bounded periplasmic space (0.9%) nucleoplasm (0.5%)" "alpha-galactosidase activity (20.6%) asparaginase activity (1.4%) endopeptidase activity (0.9%)" "IPR021354 (21.2%) IPR002252 (8.7%) IPR031704 (8.7%)" "Protein of unknown function DUF2975 (21.2%) Glycoside hydrolase family 36 (8.7%) Glycosyl hydrolase family 36, N-terminal (8.7%)" NSQFAQPLFEFSGACSGCGETPYVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.5%) GO:0022900 (14.5%) GO:0044281 (12.8%)" "GO:0005506 (14.5%) GO:0030976 (14.5%) GO:0051539 (14.5%)" "response to oxidative stress (14.5%) electron transport chain (14.5%) small molecule metabolic process (12.8%)" "iron ion binding (14.5%) thiamine pyrophosphate binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR011766 (7.8%) IPR011895 (7.8%) IPR017896 (7.8%)" "Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (7.8%)" QLVSADEFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" DADENLTTCVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016740 (100%) transferase activity (100%) IPR029044 (100%) Nucleotide-diphospho-sugar transferases (100%) YFSLFNPTTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.2%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.2%)" "IPR004199 (8.1%) IPR050347 (8.1%) IPR006102 (7.8%)" "Beta galactosidase small chain/ domain 5 (8.1%) Bacterial Beta-galactosidase (8.1%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.8%)" GDLYSVSVNGGEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.2%) IPR011659 (14.2%) IPR012393 (14.2%)" "Tail specific protease (14.2%) WD40-like beta-propeller (14.2%) Tricorn protease (14.2%)" YAMLDFK root "4.2.2.29 (80%) 3.2.1.- (20%)" "peptidoglycan lytic transglycosylase (80%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (20%)" "GO:0005975 (16.7%) GO:1904679 (5.6%) GO:0071555 (2.5%)" "GO:0016020 (8.6%) GO:0005886 (4%) GO:0000139 (1.5%)" "GO:0004553 (16.7%) GO:0030246 (15.7%) GO:0005366 (5.6%)" "carbohydrate metabolic process (16.7%) myo-inositol import across plasma membrane (5.6%) cell wall organization (2.5%)" "membrane (8.6%) plasma membrane (4%) Golgi membrane (1.5%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (16.7%) carbohydrate binding (15.7%) myo-inositol:proton symporter activity (5.6%)" "IPR033403 (7.7%) IPR000322 (7.5%) IPR025887 (7.5%)" "Domain of unknown function DUF5110 (7.7%) Glycoside hydrolase family 31, TIM barrel domain (7.5%) Glycoside hydrolase family 31, N-terminal domain (7.5%)" EYCNLHGLWK root "1.15.1.2 (99.3%) 1.-.-.- (0.3%) 1.15.-.- (0.3%)" "superoxide reductase (99.3%) Oxidoreductases (0.3%) Acting on superoxide as acceptor (0.3%)" GO:0019430 (21.8%) GO:0016020 (0.1%) "GO:0005506 (38.9%) GO:0050605 (25.6%) GO:0016491 (13.2%)" removal of superoxide radicals (21.8%) membrane (0.1%) "iron ion binding (38.9%) superoxide reductase activity (25.6%) oxidoreductase activity (13.2%)" "IPR002742 (19.8%) IPR036073 (19.8%) IPR051233 (19.7%)" "Desulfoferrodoxin, ferrous iron-binding domain (19.8%) Desulfoferrodoxin, ferrous iron-binding domain superfamily (19.8%) Desulfoferrodoxin superoxide reductase (19.7%)" LAALVNENHPLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR000847 (20%) IPR005119 (20%) IPR036388 (20%)" "LysR, HTH, N-terminal domain (20%) LysR, substrate-binding (20%) Winged helix-like DNA-binding domain superfamily (20%)" YALDLLNPLQEHVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0047355 (50%) membrane (50%) CDP-glycerol glycerophosphotransferase activity (50%) "IPR007554 (33.9%) IPR051612 (33.9%) IPR043148 (32.1%)" "CDP-glycerol glycerophosphotransferase (33.9%) Teichoic Acid Biosynthesis Enzymes (33.9%) CDP-glycerol glycerophosphotransferase, C-terminal domain (32.1%)" SSLLNAFLGEDR Bacteria Bacteria 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (31.8%) "GO:0005525 (32%) GO:0043022 (32%) GO:0016787 (4.2%)" ribosome biogenesis (31.8%) "GTP binding (32%) ribosome binding (32%) hydrolase activity (4.2%)" "IPR005225 (14.4%) IPR006073 (14.4%) IPR031166 (14.4%)" "Small GTP-binding domain (14.4%) GTP binding domain (14.4%) EngA-type guanine nucleotide-binding (G) domain (14.4%)" YSTVQNWYPGDEHGK Pseudomonadati Bacteria Pseudomonadati GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR010231 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufB (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" AQKGEDSSAYLFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (53.2%) IPR038377 (46.8%)" "Sodium/solute symporter (53.2%) Sodium/glucose symporter superfamily (46.8%)" ALFVSALR root "7.2.1.1 (98.1%) 2.4.1.109 (0.9%) 2.7.11.1 (0.9%)" "NADH:ubiquinone reductase (Na(+)-transporting) (98.1%) dolichyl-phosphate-mannose--protein mannosyltransferase (0.9%) non-specific serine/threonine protein kinase (0.9%)" "GO:0006814 (34.3%) GO:0006887 (1.6%) GO:0051601 (1.3%)" "GO:0005886 (2.6%) GO:0016020 (1.9%) GO:0000145 (1.6%)" "GO:0016655 (34.3%) GO:0016620 (2.6%) GO:0000149 (1.3%)" "sodium ion transport (34.3%) exocytosis (1.6%) exocyst localization (1.3%)" "plasma membrane (2.6%) membrane (1.9%) exocyst (1.6%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (34.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (2.6%) SNARE binding (1.3%)" "IPR008703 (17.4%) IPR022615 (17.4%) IPR056148 (17.4%)" "Na(+)-translocating NADH-quinone reductase subunit A (17.4%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (17.4%) NqrA, second alpha/beta domain (17.4%)" QGEGGLDEWLANLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (43.3%) GO:0005886 (43.3%) GO:0016787 (13.3%) guanosine tetraphosphate metabolic process (43.3%) plasma membrane (43.3%) hydrolase activity (13.3%) "IPR002912 (10%) IPR004095 (10%) IPR004811 (10%)" "ACT domain (10%) TGS (10%) RelA/SpoT family (10%)" MQVPAELQDNLVDALYACHDGVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33.3%) IPR002933 (33.3%) IPR011650 (33.3%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (33.3%) Peptidase M20, dimerisation domain (33.3%)" FLLGGAEPTTAPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.4%) IPR021120 (20.4%) IPR011051 (19.7%)" "5-keto 4-deoxyuronate isomerase (20.4%) KduI/IolB isomerase (20.4%) RmlC-like cupin domain superfamily (19.7%)" KYEDDGVSLDEEEQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0007059 (20%) GO:0051301 (20%)" GO:0005886 (20%) "GO:0003677 (20%) GO:0005524 (20%)" "chromosome segregation (20%) cell division (20%)" plasma membrane (20%) "DNA binding (20%) ATP binding (20%)" "IPR002543 (12.7%) IPR018541 (12.7%) IPR025199 (12.7%)" "FtsK domain (12.7%) FtsK gamma domain (12.7%) DNA translocase FtsK, 4TM region (12.7%)" ALEEGLEAFAGCAVVLSHDR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0045900 (12.6%) GO:0006412 (12.4%)" GO:0005737 (12.4%) "GO:0005524 (12.9%) GO:0016887 (12.9%) GO:0000049 (12.6%)" "negative regulation of translational elongation (12.6%) translation (12.4%)" cytoplasm (12.4%) "ATP binding (12.9%) ATP hydrolysis activity (12.9%) tRNA binding (12.6%)" "IPR003439 (16.9%) IPR022374 (16.9%) IPR027417 (16.9%)" "ABC transporter-like, ATP-binding domain (16.9%) Energy-dependent translational throttle protein EttA (16.9%) P-loop containing nucleoside triphosphate hydrolase (16.9%)" GMDWMYANCSTTAQR root "1.1.1.86 (89.4%) 1.1.1.- (10.1%) 1.1.1.382 (0.3%)" "ketol-acid reductoisomerase (NADP(+)) (89.4%) With NAD(+) or NADP(+) as acceptor (10.1%) ketol-acid reductoisomerase (NAD(+)) (0.3%)" "GO:0009097 (20.6%) GO:0009099 (20.6%) GO:0000002 (0.1%)" "GO:0005759 (0.9%) GO:0005739 (0.1%) GO:0042645 (0.1%)" "GO:0004455 (20.6%) GO:0046872 (20.6%) GO:0016853 (15.8%)" "isoleucine biosynthetic process (20.6%) L-valine biosynthetic process (20.6%) obsolete mitochondrial genome maintenance (0.1%)" "mitochondrial matrix (0.9%) mitochondrion (0.1%) mitochondrial nucleoid (0.1%)" "ketol-acid reductoisomerase activity (20.6%) metal ion binding (20.6%) isomerase activity (15.8%)" "IPR000506 (16.7%) IPR013023 (16.7%) IPR008927 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) Ketol-acid reductoisomerase (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%)" DYVTTSDDPQQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.- (100%) Transferring other groups (100%) "GO:0000455 (32.8%) GO:0001522 (0.3%) GO:0006364 (0.3%)" "GO:0003723 (33.1%) GO:0120159 (32.8%) GO:0009982 (0.3%)" "enzyme-directed rRNA pseudouridine synthesis (32.8%) pseudouridine synthesis (0.3%) rRNA processing (0.3%)" "RNA binding (33.1%) rRNA pseudouridine synthase activity (32.8%) pseudouridine synthase activity (0.3%)" "IPR000748 (11.2%) IPR006145 (11.2%) IPR050343 (11.2%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.2%) Pseudouridine synthase, RsuA/RluA-like (11.2%) Ribosomal RNA Pseudouridine Synthase RsuA (11.2%)" KSDLTGSVATVK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (2.2%) GO:0009279 (95.6%) GO:0015344 (2.2%) siderophore transmembrane transport (2.2%) cell outer membrane (95.6%) siderophore uptake transmembrane transporter activity (2.2%) "IPR012910 (12.5%) IPR023996 (12.5%) IPR023997 (12.5%)" "TonB-dependent receptor, plug domain (12.5%) TonB-dependent outer membrane protein, SusC/RagA (12.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.5%)" SAFDLDR root "6.3.5.5 (41.8%) 6.3.4.16 (28.8%) 5.6.2.4 (4.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (41.8%) carbamoyl-phosphate synthase (ammonia) (28.8%) DNA 3'-5' helicase (4.1%)" "GO:0006541 (5.7%) GO:0006526 (5.2%) GO:0006221 (5.1%)" "GO:0005737 (9%) GO:0005634 (2.6%) GO:0016020 (2.4%)" "GO:0005524 (7.5%) GO:0046872 (6.1%) GO:0004088 (5.7%)" "glutamine metabolic process (5.7%) L-arginine biosynthetic process (5.2%) pyrimidine nucleotide biosynthetic process (5.1%)" "cytoplasm (9%) nucleus (2.6%) membrane (2.4%)" "ATP binding (7.5%) metal ion binding (6.1%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (5.7%)" "IPR011607 (4.2%) IPR005479 (4.2%) IPR011761 (4.2%)" "Methylglyoxal synthase-like domain (4.2%) Carbamoyl phosphate synthase, ATP-binding domain (4.2%) ATP-grasp fold (4.2%)" WMANMNDSEGSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.4%) GO:0022900 (14.4%) GO:0044281 (13.8%)" "GO:0005506 (14.4%) GO:0030976 (14.4%) GO:0051539 (14.4%)" "response to oxidative stress (14.4%) electron transport chain (14.4%) small molecule metabolic process (13.8%)" "iron ion binding (14.4%) thiamine pyrophosphate binding (14.4%) 4 iron, 4 sulfur cluster binding (14.4%)" "IPR002869 (7.8%) IPR002880 (7.8%) IPR009014 (7.8%)" "Pyruvate-flavodoxin oxidoreductase, central domain (7.8%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (7.8%)" LTSVGSLR root "3.2.1.52 (86.2%) 4.1.2.10 (6.9%) 1.6.5.- (3.4%)" "beta-N-acetylhexosaminidase (86.2%) (R)-mandelonitrile lyase (6.9%) With a quinone or similar compound as acceptor (3.4%)" "GO:0005975 (10.5%) GO:0030203 (10.5%) GO:0001654 (2.9%)" "GO:0016020 (12.2%) GO:0005886 (5.9%) GO:0098552 (4.2%)" "GO:0004563 (10.5%) GO:0015562 (1.7%) GO:0016301 (1.7%)" "carbohydrate metabolic process (10.5%) glycosaminoglycan metabolic process (10.5%) eye development (2.9%)" "membrane (12.2%) plasma membrane (5.9%) side of membrane (4.2%)" "beta-N-acetylhexosaminidase activity (10.5%) efflux transmembrane transporter activity (1.7%) kinase activity (1.7%)" "IPR015883 (6.6%) IPR025705 (6.6%) IPR011658 (6.4%)" "Glycoside hydrolase family 20, catalytic domain (6.6%) Beta-hexosaminidase (6.6%) PA14 domain (6.4%)" ALWDNSLLLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006270 (14.3%) GO:0006275 (14.3%)" "GO:0005737 (14.3%) GO:0005886 (14.3%)" "GO:0003688 (14.3%) GO:0005524 (14.3%) GO:0008289 (14.3%)" "DNA replication initiation (14.3%) regulation of DNA replication (14.3%)" "cytoplasm (14.3%) plasma membrane (14.3%)" "DNA replication origin binding (14.3%) ATP binding (14.3%) lipid binding (14.3%)" "IPR024633 (10.6%) IPR001957 (10.3%) IPR003593 (10.3%)" "DnaA N-terminal domain (10.6%) Chromosomal replication control, initiator DnaA (10.3%) AAA+ ATPase domain (10.3%)" VDNLLLCGGMTYTFSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" LTANSSHMGDAVLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.2%) IPR011659 (14.2%) IPR012393 (14.2%)" "Tail specific protease (14.2%) WD40-like beta-propeller (14.2%) Tricorn protease (14.2%)" WHNVDLNQQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (26.1%) GO:0009341 (26.1%) "GO:0004565 (26.1%) GO:0030246 (21.6%)" lactose catabolic process (26.1%) beta-galactosidase complex (26.1%) "beta-galactosidase activity (26.1%) carbohydrate binding (21.6%)" "IPR050347 (8.7%) IPR004199 (8%) IPR006102 (8%)" "Bacterial Beta-galactosidase (8.7%) Beta galactosidase small chain/ domain 5 (8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8%)" LLCNLLGNDVEK Pseudomonadati Bacteria Pseudomonadati 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (51.2%) IPR032466 (48.8%)" "Uronate isomerase (51.2%) Metal-dependent hydrolase (48.8%)" GFDGGNMLQGLAQHVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006261 (16.9%) GO:0009360 (16.4%) "GO:0003887 (16.9%) GO:0005524 (16.9%) GO:0046872 (16.9%)" DNA-templated DNA replication (16.9%) DNA polymerase III complex (16.4%) "DNA-directed DNA polymerase activity (16.9%) ATP binding (16.9%) metal ion binding (16.9%)" "IPR022754 (12.6%) IPR045085 (12.6%) IPR050238 (12.6%)" "DNA polymerase III, gamma subunit, domain III (12.6%) DNA polymerase III, subunit gamma/tau, helical lid domain (12.6%) DNA Replication and Repair Clamp Loader Complex (12.6%)" SDGGMLTDDHLPVNEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0008270 (47.8%) GO:0016603 (47.8%) GO:0016740 (2.2%)" "zinc ion binding (47.8%) glutaminyl-peptide cyclotransferase activity (47.8%) transferase activity (2.2%)" "IPR007484 (52.2%) IPR040234 (47.8%)" "Peptidase M28 (52.2%) Glutaminyl-peptide cyclotransferase-like (47.8%)" YPMQLVDK Bacteria Bacteria "3.5.1.108 (56.1%) 4.2.1.59 (43.9%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (56.1%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (43.9%)" "GO:0009245 (14.6%) GO:0006633 (12.8%)" "GO:0016020 (14.6%) GO:0005737 (14.5%)" "GO:0103117 (14.4%) GO:0046872 (14.3%) GO:0019171 (7.1%)" "lipid A biosynthetic process (14.6%) fatty acid biosynthetic process (12.8%)" "membrane (14.6%) cytoplasm (14.5%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.4%) metal ion binding (14.3%) (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity (7.1%)" "IPR013114 (14.8%) IPR004463 (14.6%) IPR029069 (14.6%)" "Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%) UDP-3-O-acyl N-acetylglucosamine deacetylase (14.6%) HotDog domain superfamily (14.6%)" DNPNCDLTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DSGNLLPGHGGMLDR Bacteria Bacteria "2.7.7.41 (99.7%) 2.7.-.- (0.3%)" "phosphatidate cytidylyltransferase (99.7%) Transferring phosphorus-containing groups (0.3%)" GO:0016024 (33.3%) GO:0005886 (33.3%) "GO:0004605 (33.3%) GO:0016779 (0.1%)" CDP-diacylglycerol biosynthetic process (33.3%) plasma membrane (33.3%) "phosphatidate cytidylyltransferase activity (33.3%) nucleotidyltransferase activity (0.1%)" IPR000374 (100%) Phosphatidate cytidylyltransferase (100%) GFEYGEGFAGVTAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.3.5 (100%) chorismate synthase (100%) "GO:0008652 (16.7%) GO:0009073 (16.7%) GO:0009423 (16.7%)" GO:0005829 (16.7%) "GO:0004107 (16.7%) GO:0010181 (16.7%)" "amino acid biosynthetic process (16.7%) aromatic amino acid family biosynthetic process (16.7%) chorismate biosynthetic process (16.7%)" cytosol (16.7%) "chorismate synthase activity (16.7%) FMN binding (16.7%)" "IPR000453 (34%) IPR020541 (34%) IPR035904 (32%)" "Chorismate synthase (34%) Chorismate synthase, conserved site (34%) Chorismate synthase AroC superfamily (32%)" LHQQEAQLVAEAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.2%) GO:0017038 (11.2%) GO:0043952 (11.2%)" "GO:0005829 (11.2%) GO:0005886 (11.2%) GO:0031522 (11.2%)" "GO:0005524 (11.2%) GO:0046872 (10.8%)" "protein targeting (11.2%) protein import (11.2%) protein transport by the Sec complex (11.2%)" "cytosol (11.2%) plasma membrane (11.2%) cell envelope Sec protein transport complex (11.2%)" "ATP binding (11.2%) metal ion binding (10.8%)" "IPR000185 (8%) IPR001650 (8%) IPR011115 (8%)" "Protein translocase subunit SecA (8%) Helicase, C-terminal domain-like (8%) SecA DEAD-like, N-terminal (8%)" GEWAYTHDYPTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" WVSGYTTR root GO:0043190 (50%) GO:0005548 (50%) ATP-binding cassette (ABC) transporter complex (50%) phospholipid transporter activity (50%) "IPR030802 (90.7%) IPR001360 (2.3%) IPR017853 (2.3%)" "ABC transporter permease MalE (90.7%) Glycoside hydrolase family 1 (2.3%) Glycoside hydrolase superfamily (2.3%)" NNFTSADAYTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" LLSLELQSMPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25.1%) GO:0005737 (25.1%) "GO:0004134 (25.1%) GO:2001070 (24.7%)" carbohydrate metabolic process (25.1%) cytoplasm (25.1%) "4-alpha-glucanotransferase activity (25.1%) starch binding (24.7%)" "IPR003385 (20.4%) IPR002044 (20.1%) IPR017853 (20.1%)" "Glycoside hydrolase, family 77 (20.4%) Carbohydrate binding module family 20 (20.1%) Glycoside hydrolase superfamily (20.1%)" LGQAGEFDYSGSQALK root "6.3.4.16 (45.1%) 6.3.5.5 (22.9%) 2.1.3.2 (13%)" "carbamoyl-phosphate synthase (ammonia) (45.1%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (22.9%) aspartate carbamoyltransferase (13%)" "GO:0006541 (9.1%) GO:0006207 (8.9%) GO:0006228 (5.7%)" "GO:0005829 (5.7%) GO:0005951 (3.2%) GO:0005739 (1.1%)" "GO:0005524 (10.4%) GO:0004088 (10.4%) GO:0046872 (10%)" "glutamine metabolic process (9.1%) 'de novo' pyrimidine nucleobase biosynthetic process (8.9%) UTP biosynthetic process (5.7%)" "cytosol (5.7%) carbamoyl-phosphate synthase complex (3.2%) mitochondrion (1.1%)" "ATP binding (10.4%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (10.4%) metal ion binding (10%)" "IPR016185 (8.7%) IPR005483 (8.7%) IPR005479 (8%)" "Pre-ATP-grasp domain superfamily (8.7%) Carbamoyl phosphate synthase, CPSase domain (8.7%) Carbamoyl phosphate synthase, ATP-binding domain (8%)" AYGPTEGFELHVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (32%) GO:0006730 (1.3%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (32%) one-carbon metabolic process (1.3%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.7%) IPR020628 (33.3%) IPR027417 (31.9%)" "Formate-tetrahydrofolate ligase, FTHFS (34.7%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33.3%) P-loop containing nucleoside triphosphate hydrolase (31.9%)" NVKPLDDFNWDEFENGTSANVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.6%) IPR012340 (24.6%) IPR035104 (24.6%)" "S1 domain (24.6%) Nucleic acid-binding, OB-fold (24.6%) Ribosomal protein S1-like (24.6%)" LVVDEPSVVALDR root "GO:0000902 (25.4%) GO:0008360 (25.4%) GO:0043093 (0.1%)" "GO:0005737 (25.4%) GO:0005856 (0.1%) GO:0005886 (0.1%)" "GO:0005524 (23.1%) GO:0016787 (0.5%)" "cell morphogenesis (25.4%) regulation of cell shape (25.4%) FtsZ-dependent cytokinesis (0.1%)" "cytoplasm (25.4%) cytoskeleton (0.1%) plasma membrane (0.1%)" "ATP binding (23.1%) hydrolase activity (0.5%)" "IPR056546 (32.6%) IPR004753 (32.5%) IPR043129 (32.5%)" "MreB/MamK-like (32.6%) Cell shape determining protein MreB (32.5%) ATPase, nucleotide binding domain (32.5%)" GYHLSPVPQNPELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.75 (100%) tRNA dimethylallyltransferase (100%) GO:0006400 (33.8%) "GO:0052381 (33.8%) GO:0005524 (32.5%)" tRNA modification (33.8%) "tRNA dimethylallyltransferase activity (33.8%) ATP binding (32.5%)" "IPR039657 (34.2%) IPR018022 (32.9%) IPR027417 (32.9%)" "Dimethylallyltransferase (34.2%) IPP transferase (32.9%) P-loop containing nucleoside triphosphate hydrolase (32.9%)" LTELWATGDTQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (31.9%) GO:0005829 (31.9%) "GO:0008926 (31.9%) GO:0009026 (4.3%)" mannitol catabolic process (31.9%) cytosol (31.9%) "mannitol-1-phosphate 5-dehydrogenase activity (31.9%) tagaturonate reductase activity (4.3%)" "IPR013118 (21.8%) IPR013131 (21.8%) IPR008927 (18.8%)" "Mannitol dehydrogenase, C-terminal (21.8%) Mannitol dehydrogenase, N-terminal (21.8%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.8%)" TGLLTTDHGQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.29 (100%) tRNA-guanosine(34) preQ1 transglycosylase (100%) GO:0002099 (33.3%) GO:0005829 (33.3%) "GO:0008479 (32.7%) GO:0016757 (0.6%)" tRNA wobble guanine modification (33.3%) cytosol (33.3%) "tRNA-guanosine(34) queuine transglycosylase activity (32.7%) glycosyltransferase activity (0.6%)" "IPR002616 (25.1%) IPR036511 (25.1%) IPR050076 (25.1%)" "tRNA-guanine(15) transglycosylase-like (25.1%) Queuine tRNA-ribosyltransferase-like (25.1%) Archaeosine Synthase Type 1/Queuine TRNA-Ribosyltransferase (25.1%)" LLQLGAKPVTCSDSDGYLYDPDGLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.2%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" RGLVQGMEEGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0032790 (20.4%) GO:0005737 (19.4%) "GO:0003746 (20.4%) GO:0005525 (20.4%) GO:0003924 (19.4%)" ribosome disassembly (20.4%) cytoplasm (19.4%) "translation elongation factor activity (20.4%) GTP binding (20.4%) GTPase activity (19.4%)" "IPR000640 (6.4%) IPR004161 (6.4%) IPR005517 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%) Translation elongation factor EFG/EF2, domain IV (6.4%)" TNVLTASQGEALMAHR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0009409 (10%) GO:0000027 (9.8%) GO:0010467 (9.8%)" "GO:0005829 (10%) GO:1990904 (10%)" "GO:0005525 (10.1%) GO:0003924 (10%) GO:0000049 (9.8%)" "response to cold (10%) ribosomal large subunit assembly (9.8%) gene expression (9.8%)" "cytosol (10%) ribonucleoprotein complex (10%)" "GTP binding (10.1%) GTPase activity (10%) tRNA binding (9.8%)" "IPR000640 (6.7%) IPR035651 (6.7%) IPR048876 (6.7%)" "Elongation factor EFG, domain V-like (6.7%) BipA, domain V (6.7%) TypA/BipA, C-terminal domain (6.7%)" TMDFMVNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006508 (21.6%) GO:0009636 (18.9%) GO:0043418 (18.9%)" GO:0005737 (18.9%) GO:0070005 (21.6%) "proteolysis (21.6%) response to toxic substance (18.9%) homocysteine catabolic process (18.9%)" cytoplasm (18.9%) cysteine-type aminopeptidase activity (21.6%) "IPR004134 (36.1%) IPR038765 (36.1%) IPR000169 (18.1%)" "Peptidase C1B, bleomycin hydrolase (36.1%) Papain-like cysteine peptidase superfamily (36.1%) Cysteine peptidase, cysteine active site (18.1%)" VAQLKNELENTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.1%) GO:0005737 (16.2%) "GO:0005524 (17.1%) GO:0140662 (17.1%) GO:0016853 (16.2%)" protein refolding (17.1%) cytoplasm (16.2%) "ATP binding (17.1%) ATP-dependent protein folding chaperone (17.1%) isomerase activity (16.2%)" "IPR001844 (17.4%) IPR002423 (17.4%) IPR018370 (16.5%)" "Chaperonin Cpn60/GroEL (17.4%) Chaperonin Cpn60/GroEL/TCP-1 family (17.4%) Chaperonin Cpn60, conserved site (16.5%)" AKDFQPVVDEAVSLFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20.2%) GO:0008615 (19.4%)" GO:0005737 (20.2%) "GO:0004648 (20.2%) GO:0030170 (20.2%)" "L-serine biosynthetic process (20.2%) pyridoxine biosynthetic process (19.4%)" cytoplasm (20.2%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20.2%) pyridoxal phosphate binding (20.2%)" "IPR000192 (20.8%) IPR022278 (20.8%) IPR015421 (20%)" "Aminotransferase class V domain (20.8%) Phosphoserine aminotransferase (20.8%) Pyridoxal phosphate-dependent transferase, major domain (20%)" KEWVVLDATDQVVGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (20%) GO:0017148 (20%)" GO:0022625 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" cytosolic large ribosomal subunit (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (25%) IPR005823 (25%) IPR023563 (25%)" "Large ribosomal subunit protein uL13 (25%) Large ribosomal subunit protein uL13, bacteria (25%) Large ribosomal subunit protein uL13, conserved site (25%)" NAEYNHFAVFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (28.6%) GO:0009279 (42.9%) GO:0015344 (28.6%) siderophore transmembrane transport (28.6%) cell outer membrane (42.9%) siderophore uptake transmembrane transporter activity (28.6%) "IPR000531 (44.4%) IPR036942 (33.3%) IPR039426 (22.2%)" "TonB-dependent receptor-like, beta-barrel (44.4%) TonB-dependent receptor-like, beta-barrel domain superfamily (33.3%) TonB-dependent receptor-like (22.2%)" TGDDAGDGTTTATLLTQALVTEGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17%) GO:0005737 (16.4%) "GO:0005524 (17%) GO:0140662 (17%) GO:0016853 (16.4%)" protein refolding (17%) cytoplasm (16.4%) "ATP binding (17%) ATP-dependent protein folding chaperone (17%) isomerase activity (16.4%)" "IPR001844 (17%) IPR002423 (17%) IPR027413 (16.7%)" "Chaperonin Cpn60/GroEL (17%) Chaperonin Cpn60/GroEL/TCP-1 family (17%) GroEL-like equatorial domain superfamily (16.7%)" ALDGLDLK root "3.4.11.14 (21.4%) 3.1.21.3 (14.3%) 7.2.2.11 (14.3%)" "cytosol alanyl aminopeptidase (21.4%) type I site-specific deoxyribonuclease (14.3%) ABC-type Ni(2+) transporter (14.3%)" "GO:0055085 (2.3%) GO:0015833 (2.1%) GO:0046677 (1.9%)" "GO:0005886 (16%) GO:0016020 (2.4%) GO:0005634 (0.4%)" "GO:0005524 (21.2%) GO:0016887 (20.1%) GO:0015614 (5.6%)" "transmembrane transport (2.3%) peptide transport (2.1%) response to antibiotic (1.9%)" "plasma membrane (16%) membrane (2.4%) nucleus (0.4%)" "ATP binding (21.2%) ATP hydrolysis activity (20.1%) ABC-type D-xylose transporter activity (5.6%)" "IPR027417 (13.3%) IPR003593 (12.6%) IPR003439 (12.5%)" "P-loop containing nucleoside triphosphate hydrolase (13.3%) AAA+ ATPase domain (12.6%) ABC transporter-like, ATP-binding domain (12.5%)" NLDNVVPDR Pseudomonadati Bacteria Pseudomonadati 2.7.1.22 (100%) ribosylnicotinamide kinase (100%) "GO:0016301 (84.6%) GO:0050262 (15.4%)" "kinase activity (84.6%) ribosylnicotinamide kinase activity (15.4%)" "IPR025393 (50.6%) IPR029044 (49.4%)" "Domain of unknown function DUF4301 (50.6%) Nucleotide-diphospho-sugar transferases (49.4%)" LSGMNLLLDDTDHPLLLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.4.1.21 (100%) starch synthase (100%) GO:0016020 (0.3%) "GO:0016757 (85.2%) GO:0009011 (13.5%) GO:0004373 (0.9%)" membrane (0.3%) "glycosyltransferase activity (85.2%) alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity (13.5%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (0.9%)" IPR013534 (100%) Starch synthase, catalytic domain (100%) KGEEELSMDDLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (22.3%) IPR003379 (22.3%) IPR055268 (22.3%)" "Pyruvate carboxyltransferase (22.3%) Carboxylase, conserved domain (22.3%) Pyruvate carboxylase-like (22.3%)" NLPTLLFFK Pseudomonadati Bacteria Pseudomonadati GO:0045454 (29.9%) "GO:0005829 (29.9%) GO:0005737 (5.1%)" GO:0015035 (35%) cell redox homeostasis (29.9%) "cytosol (29.9%) cytoplasm (5.1%)" protein-disulfide reductase activity (35%) "IPR005746 (25.2%) IPR013766 (25.2%) IPR036249 (24.9%)" "Thioredoxin (25.2%) Thioredoxin domain (25.2%) Thioredoxin-like superfamily (24.9%)" LLFQGKPEELAENK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0055085 (23.3%) "GO:0043190 (23.3%) GO:0005886 (2.3%)" "GO:0005524 (25.6%) GO:0016887 (25.6%)" transmembrane transport (23.3%) "ATP-binding cassette (ABC) transporter complex (23.3%) plasma membrane (2.3%)" "ATP binding (25.6%) ATP hydrolysis activity (25.6%)" "IPR003439 (21.2%) IPR051120 (21.2%) IPR003593 (19.2%)" "ABC transporter-like, ATP-binding domain (21.2%) ABC Transporter, Amino Acid and LPS Transport (21.2%) AAA+ ATPase domain (19.2%)" APFFDENR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006826 (30%) GO:0005993 (3.3%)" GO:0009279 (63.3%) GO:0004555 (3.3%) "iron ion transport (30%) trehalose catabolic process (3.3%)" cell outer membrane (63.3%) alpha,alpha-trehalase activity (3.3%) "IPR000531 (12.2%) IPR008969 (12.2%) IPR012910 (12.2%)" "TonB-dependent receptor-like, beta-barrel (12.2%) Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%)" LLVSLSPHAHGNESVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) "GO:0022900 (33.3%) GO:0055085 (33.3%)" GO:0005886 (33.3%) "electron transport chain (33.3%) transmembrane transport (33.3%)" plasma membrane (33.3%) "IPR004338 (50%) IPR011303 (50%)" "Ion-translocating oxidoreductase NqrB/RnfD (50%) Ion-translocating oxidoreductase complex subunit RnfD, bacterial (50%)" LDESGEEVYWEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.3%) GO:0005829 (25.3%) "GO:0008733 (25.3%) GO:0030145 (24.2%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.3%) cytosol (25.3%) "L-arabinose isomerase activity (25.3%) manganese ion binding (24.2%)" "IPR003762 (14.7%) IPR024664 (14.7%) IPR055390 (14.7%)" "L-arabinose isomerase (14.7%) L-arabinose isomerase, C-terminal (14.7%) L-arabinose isomerase, central domain (14.7%)" GLENSSGPLGQGHALAAGAAVAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.2.1.1 (95%) 1.2.4.4 (2.5%) 2.2.1.- (2.5%)" "transketolase (95%) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (2.5%) Transketolases and transaldolases (2.5%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (24.4%) GO:0003863 (0.6%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (24.4%) branched-chain 2-oxo acid dehydrogenase activity (0.6%)" "IPR005474 (12.7%) IPR029061 (12.7%) IPR033247 (12.7%)" "Transketolase, N-terminal (12.7%) Thiamin diphosphate-binding fold (12.7%) Transketolase family (12.7%)" YDGVGAYNNDGTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0000272 (29%) GO:0005576 (29%) "GO:0030570 (29%) GO:0004557 (12.9%)" polysaccharide catabolic process (29%) extracellular region (29%) "pectate lyase activity (29%) alpha-galactosidase activity (12.9%)" "IPR002022 (18.8%) IPR011050 (18.8%) IPR012334 (18.8%)" "Pectate lyase (18.8%) Pectin lyase fold/virulence factor (18.8%) Pectin lyase fold (18.8%)" LQLFDLLGLHPNQQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.11.9 (96.6%) 3.4.-.- (3.4%)" "Xaa-Pro aminopeptidase (96.6%) Acting on peptide bonds (peptidases) (3.4%)" GO:0006508 (25%) GO:0005829 (25%) "GO:0030145 (25%) GO:0070006 (25%)" proteolysis (25%) cytosol (25%) "manganese ion binding (25%) metalloaminopeptidase activity (25%)" "IPR000994 (20%) IPR007865 (20%) IPR029149 (20%)" "Peptidase M24 (20%) Aminopeptidase P, N-terminal (20%) Creatinase/Aminopeptidase P/Spt16, N-terminal (20%)" YFVNPTGK Bacteria Bacteria 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%)" GO:0005737 (16.6%) "GO:0004478 (16.7%) GO:0005524 (16.7%) GO:0000287 (16.4%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%)" cytoplasm (16.6%) "methionine adenosyltransferase activity (16.7%) ATP binding (16.7%) magnesium ion binding (16.4%)" "IPR002133 (16.7%) IPR022628 (16.7%) IPR022629 (16.7%)" "S-adenosylmethionine synthetase (16.7%) S-adenosylmethionine synthetase, N-terminal (16.7%) S-adenosylmethionine synthetase, central domain (16.7%)" GNAAGTGYWTWYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.3%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.3%)" ATALHNLSEYDFTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.78 (100%) 6,7-dimethyl-8-ribityllumazine synthase (100%) GO:0009231 (24%) "GO:0005829 (24%) GO:0009349 (24%)" "GO:0000906 (24%) GO:0016874 (4%)" riboflavin biosynthetic process (24%) "cytosol (24%) riboflavin synthase complex (24%)" "6,7-dimethyl-8-ribityllumazine synthase activity (24%) ligase activity (4%)" "IPR002180 (33.3%) IPR034964 (33.3%) IPR036467 (33.3%)" "Lumazine/riboflavin synthase (33.3%) Lumazine synthase (33.3%) Lumazine/riboflavin synthase superfamily (33.3%)" LGGATFQVPTELRPDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) GO:0015935 (20%) "GO:0003735 (20%) GO:0019843 (20%) GO:0000049 (19.8%)" translation (20%) small ribosomal subunit (20%) "structural constituent of ribosome (20%) rRNA binding (20%) tRNA binding (19.8%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" NPLLESENFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.1.7.2 (66.7%) 2.7.6.5 (33.3%)" "guanosine-3',5'-bis(diphosphate) 3'-diphosphatase (66.7%) GTP diphosphokinase (33.3%)" GO:0015969 (43%) GO:0005886 (44.4%) "GO:0016787 (7.3%) GO:0016301 (3.3%) GO:0008893 (1.3%)" guanosine tetraphosphate metabolic process (43%) plasma membrane (44.4%) "hydrolase activity (7.3%) kinase activity (3.3%) guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity (1.3%)" "IPR043519 (10.3%) IPR004095 (10.2%) IPR007685 (10.2%)" "Nucleotidyltransferase superfamily (10.3%) TGS (10.2%) RelA/SpoT (10.2%)" VGGQEVRPLDLSLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (31.6%) GO:0045259 (31.6%)" "GO:0046933 (31.6%) GO:0016787 (5.3%)" "plasma membrane (31.6%) proton-transporting ATP synthase complex (31.6%)" "proton-transporting ATP synthase activity, rotational mechanism (31.6%) hydrolase activity (5.3%)" "IPR000568 (33.3%) IPR035908 (33.3%) IPR045083 (33.3%)" "ATP synthase, F0 complex, subunit A (33.3%) ATP synthase, F0 complex, subunit A superfamily (33.3%) ATP synthase, F0 complex, subunit A, bacterial/mitochondria (33.3%)" LLGTDKTTDLALLK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.4.21.- (50%) 3.4.21.107 (50%)" "Serine endopeptidases (50%) peptidase Do (50%)" GO:0006508 (48.7%) "GO:0016020 (1.3%) GO:0042597 (1.3%)" GO:0004252 (48.7%) proteolysis (48.7%) "membrane (1.3%) periplasmic space (1.3%)" serine-type endopeptidase activity (48.7%) "IPR001478 (18.3%) IPR001940 (17.8%) IPR009003 (17.8%)" "PDZ domain (18.3%) Peptidase S1C (17.8%) Peptidase S1, PA clan (17.8%)" VSLTVENSTEFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR011773 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) DNA-directed RNA polymerase, alpha subunit (16.7%)" LLNAGELQNQGVELALNAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.8%) IPR023996 (14.8%) IPR023997 (14.8%)" "TonB-dependent receptor, plug domain (14.8%) TonB-dependent outer membrane protein, SusC/RagA (14.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.8%)" TFGAAFATYELNDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR012910 (13.1%) IPR023996 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%)" SENNTTVNSAKPFVDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.148 (100%) thymidylate synthase (FAD) (100%) "GO:0006231 (18%) GO:0032259 (9.8%)" "GO:0004799 (18%) GO:0050660 (18%) GO:0050797 (18%)" "dTMP biosynthetic process (18%) methylation (9.8%)" "thymidylate synthase activity (18%) flavin adenine dinucleotide binding (18%) thymidylate synthase (FAD) activity (18%)" "IPR003669 (52.4%) IPR036098 (47.6%)" "Thymidylate synthase ThyX (52.4%) Thymidylate synthase ThyX superfamily (47.6%)" SGTTTETALAFR Bacteria Bacteria 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.2%) GO:0006096 (14.2%) GO:0051156 (14.2%)" "GO:0005829 (14.2%) GO:0016020 (0.2%)" "GO:0004347 (14.2%) GO:0048029 (14.2%) GO:0097367 (14.2%)" "gluconeogenesis (14.2%) glycolytic process (14.2%) glucose 6-phosphate metabolic process (14.2%)" "cytosol (14.2%) membrane (0.2%)" "glucose-6-phosphate isomerase activity (14.2%) monosaccharide binding (14.2%) carbohydrate derivative binding (14.2%)" "IPR001672 (19.6%) IPR046348 (19.5%) IPR018189 (19.5%)" "Phosphoglucose isomerase (PGI) (19.6%) SIS domain superfamily (19.5%) Phosphoglucose isomerase, conserved site (19.5%)" FMAVPVAFGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (24.6%) GO:0016887 (24.6%) GO:0051082 (24.6%)" "ATP binding (24.6%) ATP hydrolysis activity (24.6%) unfolded protein binding (24.6%)" "IPR001404 (18.7%) IPR020575 (18.7%) IPR036890 (18.7%)" "Heat shock protein Hsp90 family (18.7%) Heat shock protein Hsp90, N-terminal (18.7%) Histidine kinase/HSP90-like ATPase superfamily (18.7%)" HCAGFAGLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (40%) GO:0016491 (10%)" "iron ion binding (50%) peroxidase activity (40%) oxidoreductase activity (10%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" LGTFNPNTNPATVDLNFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005737 (25%) GO:0015935 (25%)" GO:0003735 (25%) translation (25%) "cytoplasm (25%) small ribosomal subunit (25%)" structural constituent of ribosome (25%) "IPR000307 (50%) IPR023803 (50%)" "Small ribosomal subunit protein bS16 (50%) Small ribosomal subunit protein bS16 domain superfamily (50%)" SLLSYLPSNNTEEAPRVECTDPLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.-.-.- (100%) Ligases (100%) "GO:0015977 (21.4%) GO:0006633 (10%)" GO:0009317 (21.4%) "GO:0004658 (24.3%) GO:0003989 (21.4%) GO:0016740 (1.4%)" "carbon fixation (21.4%) fatty acid biosynthetic process (10%)" acetyl-CoA carboxylase complex (21.4%) "propionyl-CoA carboxylase activity (24.3%) acetyl-CoA carboxylase activity (21.4%) transferase activity (1.4%)" "IPR011762 (18.9%) IPR011763 (18.9%) IPR034733 (18.9%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.9%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.9%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.9%)" EQAEALQAGLQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (50%) IPR024930 (50%)" "Chaperone protein Skp (50%) Skp domain superfamily (50%)" LHQFDKVELVR root 6.1.1.11 (100%) serine--tRNA ligase (100%) "GO:0006434 (24.7%) GO:0016260 (0.7%)" GO:0005737 (24.7%) "GO:0004828 (24.7%) GO:0005524 (24.7%) GO:0016740 (0.2%)" "seryl-tRNA aminoacylation (24.7%) selenocysteine biosynthetic process (0.7%)" cytoplasm (24.7%) "serine-tRNA ligase activity (24.7%) ATP binding (24.7%) transferase activity (0.2%)" "IPR002314 (13.4%) IPR002317 (13.4%) IPR006195 (13.4%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (13.4%) Serine-tRNA ligase, type1 (13.4%) Aminoacyl-tRNA synthetase, class II (13.4%)" GGWGQTGNQSGLGDYSYLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" ELDLTDQYAVEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.271 (100%) GDP-L-fucose synthase (100%) GO:0042351 (24.3%) "GO:0016853 (25.7%) GO:0050577 (25.7%) GO:0070401 (24.3%)" 'de novo' GDP-L-fucose biosynthetic process (24.3%) "isomerase activity (25.7%) GDP-L-fucose synthase activity (25.7%) NADP+ binding (24.3%)" "IPR001509 (33.3%) IPR028614 (33.3%) IPR036291 (33.3%)" "NAD-dependent epimerase/dehydratase (33.3%) GDP-L-fucose synthase/GDP-L-colitose synthase (33.3%) NAD(P)-binding domain superfamily (33.3%)" KDGFTLAQELR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (17.8%) IPR039420 (17.8%) IPR001867 (17.7%)" "Signal transduction response regulator, receiver domain (17.8%) Transcriptional regulatory protein WalR-like (17.8%) OmpR/PhoB-type DNA-binding domain (17.7%)" GLHAGLECGLFSER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25.1%) GO:0005829 (25.1%) "GO:0070573 (25.1%) GO:0046872 (24.7%)" proteolysis (25.1%) cytosol (25.1%) "metallodipeptidase activity (25.1%) metal ion binding (24.7%)" "IPR001160 (35.6%) IPR002933 (35%) IPR011650 (29.4%)" "Peptidase M20C, Xaa-His dipeptidase (35.6%) Peptidase M20 (35%) Peptidase M20, dimerisation domain (29.4%)" LYACSFEVTDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR015943 (66.7%) IPR011047 (22.2%) IPR011044 (11.1%)" "WD40/YVTN repeat-like-containing domain superfamily (66.7%) Quinoprotein alcohol dehydrogenase-like superfamily (22.2%) Quinoprotein amine dehydrogenase, beta chain-like (11.1%)" LGADVTVLYR Bacteria Bacteria "1.4.1.13 (62.5%) 1.8.1.7 (37.5%)" "glutamate synthase (NADPH) (62.5%) glutathione-disulfide reductase (37.5%)" "GO:0006749 (2.3%) GO:0034599 (2.3%) GO:0045454 (2.3%)" GO:0005829 (2.3%) "GO:0051536 (40%) GO:0016491 (38.5%) GO:0004355 (3.1%)" "glutathione metabolic process (2.3%) cellular response to oxidative stress (2.3%) cell redox homeostasis (2.3%)" cytosol (2.3%) "iron-sulfur cluster binding (40%) oxidoreductase activity (38.5%) glutamate synthase (NADPH) activity (3.1%)" "IPR023753 (22.6%) IPR036188 (21.8%) IPR028261 (21.4%)" "FAD/NAD(P)-binding domain (22.6%) FAD/NAD(P)-binding domain superfamily (21.8%) Dihydroprymidine dehydrogenase domain II (21.4%)" YVVGHSVSEFFLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" QLPVYLDQTKPVEQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" GDGVFQFANPSDMPLKYPSSYYSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" AYGDAEHNVWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" ESYDFVLR root "GO:0051782 (12.5%) GO:0007265 (5.8%)" "GO:0009279 (18.3%) GO:0005829 (12.5%) GO:0009898 (12.5%)" "GO:0005524 (12.5%) GO:0016887 (12.5%) GO:0005085 (5.8%)" "negative regulation of cell division (12.5%) Ras protein signal transduction (5.8%)" "cell outer membrane (18.3%) cytosol (12.5%) cytoplasmic side of plasma membrane (12.5%)" "ATP binding (12.5%) ATP hydrolysis activity (12.5%) guanyl-nucleotide exchange factor activity (5.8%)" "IPR012944 (12.7%) IPR033985 (12.7%) IPR011990 (11.6%)" "RagB/SusD domain (12.7%) SusD-like, N-terminal (12.7%) Tetratricopeptide-like helical domain superfamily (11.6%)" LGQSSTTLSGGESQR Bacteria Bacteria 3.1.25.- (100%) Site-specific endodeoxyribonucleases specific for altered bases (100%) "GO:0006289 (12.1%) GO:0006281 (0.5%) GO:0006974 (0%)" "GO:0005737 (12.6%) GO:0009380 (12.1%) GO:0005829 (0%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0016887 (12.5%)" "nucleotide-excision repair (12.1%) DNA repair (0.5%) DNA damage response (0%)" "cytoplasm (12.6%) excinuclease repair complex (12.1%) cytosol (0%)" "DNA binding (12.6%) ATP binding (12.6%) ATP hydrolysis activity (12.5%)" "IPR027417 (14.5%) IPR003439 (14.5%) IPR017871 (14.2%)" "P-loop containing nucleoside triphosphate hydrolase (14.5%) ABC transporter-like, ATP-binding domain (14.5%) ABC transporter-like, conserved site (14.2%)" LALNSAVYTDGQVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" GLAAGVNVTSSSGQPGASPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LNLLELATR root "6.3.5.5 (92.5%) 4.1.1.35 (7.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (92.5%) UDP-glucuronate decarboxylase (7.5%)" "GO:0006541 (13.3%) GO:0006526 (12.4%) GO:0006221 (12.1%)" "GO:0005737 (13.9%) GO:1990904 (0.6%) GO:0016020 (0.3%)" "GO:0004088 (13.3%) GO:0005524 (13.3%) GO:0046872 (12.7%)" "glutamine metabolic process (13.3%) L-arginine biosynthetic process (12.4%) pyrimidine nucleotide biosynthetic process (12.1%)" "cytoplasm (13.9%) ribonucleoprotein complex (0.6%) membrane (0.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.3%) ATP binding (13.3%) metal ion binding (12.7%)" "IPR005479 (9.9%) IPR011607 (9.9%) IPR011761 (9.9%)" "Carbamoyl phosphate synthase, ATP-binding domain (9.9%) Methylglyoxal synthase-like domain (9.9%) ATP-grasp fold (9.9%)" GMFSMMNYFLPLK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.3%) GO:0005829 (17.3%) "GO:0004612 (17.3%) GO:0005524 (17.3%) GO:0046872 (17.3%)" gluconeogenesis (17.3%) cytosol (17.3%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.3%) ATP binding (17.3%) metal ion binding (17.3%)" "IPR001272 (25.1%) IPR008210 (25.1%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.1%) Phosphoenolpyruvate carboxykinase, N-terminal (25.1%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" GSDLPEEDRDYYLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (16.4%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (16.4%)" "IPR003953 (14.3%) IPR015939 (14.3%) IPR030664 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.3%)" SSNPSLLTDEGVVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (48.1%) "GO:0004553 (48.1%) GO:0016787 (3.7%)" carbohydrate metabolic process (48.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.1%) hydrolase activity (3.7%)" "IPR046780 (23.2%) IPR032291 (20.3%) IPR050727 (20.3%)" "Atrophied bacterial Ig domain (23.2%) Extracellular endo-alpha-(1->5)-L-arabinanase, C-terminal (20.3%) Glycosyl hydrolase 43 family arabinanases (20.3%)" DFLQLDTPPEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.2%) IPR007644 (8.2%) IPR015712 (8.2%)" "RNA polymerase Rpb2, domain 2 (8.2%) RNA polymerase, beta subunit, protrusion (8.2%) DNA-directed RNA polymerase, subunit 2 (8.2%)" NQNEFPWDNADVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0120147 (100%) formylglycine-generating oxidase activity (100%) "IPR005532 (26.1%) IPR051043 (26.1%) IPR016187 (23.9%)" "Sulfatase-modifying factor enzyme-like domain (26.1%) Sulfatase Modifying Factor and Kinase (26.1%) C-type lectin fold (23.9%)" GQEYPMVYER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (49.3%) "GO:0004556 (49.3%) GO:0016301 (1.4%)" oligosaccharide catabolic process (49.3%) "alpha-amylase activity (49.3%) kinase activity (1.4%)" "IPR006047 (26.4%) IPR017853 (24.8%) IPR045857 (24.8%)" "Glycosyl hydrolase family 13, catalytic domain (26.4%) Glycoside hydrolase superfamily (24.8%) Oligo-1,6-glucosidase, domain 2 (24.8%)" FGLTSAELLTALKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.7%) GO:0008295 (19.7%) GO:0033388 (19.7%)" "GO:0008792 (19.7%) GO:0046872 (19.7%) GO:0004497 (1.6%)" "L-arginine catabolic process (19.7%) spermidine biosynthetic process (19.7%) putrescine biosynthetic process from arginine (19.7%)" "arginine decarboxylase activity (19.7%) metal ion binding (19.7%) monooxygenase activity (1.6%)" "IPR002985 (11.4%) IPR022644 (11.4%) IPR022653 (11.4%)" "Arginine decarboxylase (11.4%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.4%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.4%)" VSLNAPEGTPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) NANGMEVCLTNYGGR Bacteroidota Bacteria Pseudomonadati Bacteroidota "5.1.3.3 (93.5%) 5.1.3.- (6.5%)" "aldose 1-epimerase (93.5%) Acting on carbohydrates and derivatives (6.5%)" "GO:0006006 (20.3%) GO:0033499 (20.3%)" GO:0005737 (20.3%) "GO:0004034 (20.3%) GO:0030246 (19%)" "glucose metabolic process (20.3%) galactose catabolic process via UDP-galactose, Leloir pathway (20.3%)" cytoplasm (20.3%) "aldose 1-epimerase activity (20.3%) carbohydrate binding (19%)" "IPR008183 (17.3%) IPR047215 (17.3%) IPR018052 (16.8%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.3%) Galactose mutarotase-like (17.3%) Aldose 1-epimerase, conserved site (16.8%)" NQGLEFSLSSQNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" VNDKYLQTSYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.8%) IPR015171 (14.8%) IPR019492 (14.8%)" "Glycosyl hydrolase family 13, catalytic domain (14.8%) Cyclomaltodextrinase, N-terminal (14.8%) Cyclo-malto-dextrinase, C-terminal (14.8%)" KYLVSLSK root "2.7.7.6 (99.3%) 2.7.11.1 (0.7%)" "DNA-directed RNA polymerase (99.3%) non-specific serine/threonine protein kinase (0.7%)" "GO:0006351 (15.1%) GO:0000462 (0.6%) GO:0015031 (0.6%)" "GO:0000428 (15.1%) GO:0030686 (0.6%) GO:0032040 (0.6%)" "GO:0003677 (15.2%) GO:0003899 (15.1%) GO:0000287 (14.3%)" "DNA-templated transcription (15.1%) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (0.6%) protein transport (0.6%)" "DNA-directed RNA polymerase complex (15.1%) 90S preribosome (0.6%) small-subunit processome (0.6%)" "DNA binding (15.2%) DNA-directed RNA polymerase activity (15.1%) magnesium ion binding (14.3%)" "IPR007081 (8.6%) IPR045867 (8.6%) IPR007083 (8.6%)" "RNA polymerase Rpb1, domain 5 (8.6%) DNA-directed RNA polymerase, subunit beta-prime (8.6%) RNA polymerase Rpb1, domain 4 (8.6%)" VGDLAMLQAGTTFSK Pseudomonadati Bacteria Pseudomonadati 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (31.1%) GO:0008610 (3.3%)" GO:0016020 (31.1%) GO:0008780 (34.4%) "lipid A biosynthetic process (31.1%) lipid biosynthetic process (3.3%)" membrane (31.1%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.4%) "IPR010137 (20.7%) IPR029098 (20.7%) IPR011004 (20%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.7%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.7%) Trimeric LpxA-like superfamily (20%)" MQLPVLLLLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0000028 (14.3%) "GO:0005829 (14.3%) GO:0005886 (14.3%)" "GO:0003924 (14.3%) GO:0005525 (14.3%) GO:0043024 (14.3%)" ribosomal small subunit assembly (14.3%) "cytosol (14.3%) plasma membrane (14.3%)" "GTPase activity (14.3%) GTP binding (14.3%) ribosomal small subunit binding (14.3%)" "IPR004044 (12.7%) IPR005225 (12.7%) IPR005662 (12.7%)" "K Homology domain, type 2 (12.7%) Small GTP-binding domain (12.7%) GTPase Era-like (12.7%)" NLPNLDPDSSYNTSGLGLEYGSLPSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (12.8%) GO:0009279 (87.2%) iron ion transport (12.8%) cell outer membrane (87.2%) "IPR012910 (14%) IPR023996 (14%) IPR023997 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%)" YLYAQNMLFPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR021280 (47.8%) IPR052724 (47.8%) IPR011990 (4.3%)" "Protein O-mannosyl-transferase TMEM260-like (47.8%) Glycosyltransferase 117 domain-containing protein (47.8%) Tetratricopeptide-like helical domain superfamily (4.3%)" LQEFPHFYLVDVTGLNAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005840 (52.4%) GO:1990904 (47.6%)" "ribosome (52.4%) ribonucleoprotein complex (47.6%)" "IPR001790 (34.4%) IPR047865 (34.4%) IPR043141 (31.3%)" "Large ribosomal subunit protein uL10 (34.4%) Large ribosomal subunit protein uL10, bacteria/organella (34.4%) Large ribosomal subunit protein uL10-like domain superfamily (31.3%)" QAALEQDGTLVEALSNAMFR Pseudomonadati Bacteria Pseudomonadati GO:0005829 (25%) "GO:0003743 (25%) GO:0043022 (25%) GO:0019843 (22%)" cytosol (25%) "translation initiation factor activity (25%) ribosome binding (25%) rRNA binding (22%)" "IPR004368 (29.1%) IPR006196 (29.1%) IPR012340 (29.1%)" "Translation initiation factor IF-1 (29.1%) RNA-binding domain, S1, IF1 type (29.1%) Nucleic acid-binding, OB-fold (29.1%)" STVPETLLGVPVAQDSYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023996 (14.7%) IPR023997 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein, SusC/RagA (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%)" SGRPGPVVLDFTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR012000 (12.8%) IPR012001 (12.8%) IPR045229 (12.8%)" "Thiamine pyrophosphate enzyme, central domain (12.8%) Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (12.8%) Thiamine pyrophosphate enzyme (12.8%)" GQGYGNLSFSYDQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" LGGATFQVPTELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) GO:0015935 (20%) "GO:0003735 (20%) GO:0019843 (20%) GO:0000049 (19.9%)" translation (20%) small ribosomal subunit (20%) "structural constituent of ribosome (20%) rRNA binding (20%) tRNA binding (19.9%)" "IPR000235 (24.9%) IPR005717 (24.9%) IPR023798 (24.9%)" "Small ribosomal subunit protein uS7 (24.9%) Small ribosomal subunit protein uS7, bacteria/organella (24.9%) Small ribosomal subunit protein uS7 domain (24.9%)" FFEVGNTYLYNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (8%) IPR004532 (7.8%) IPR005121 (7.8%)" "Phenylalanyl tRNA synthetase beta chain, core domain (8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%) Ferrodoxin-fold anticodon-binding domain (7.8%)" FAFEEYDDAYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016491 (50%) GO:0008270 (47.5%) GO:0046872 (2.5%)" "oxidoreductase activity (50%) zinc ion binding (47.5%) metal ion binding (2.5%)" "IPR011032 (16.9%) IPR013149 (16.9%) IPR013154 (16.9%)" "GroES-like superfamily (16.9%) Alcohol dehydrogenase-like, C-terminal (16.9%) Alcohol dehydrogenase-like, N-terminal (16.9%)" TDKNAEPDPQYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.8%) GO:0009090 (17.8%) GO:0009088 (10.9%)" GO:0005829 (17.8%) "GO:0004072 (17.8%) GO:0005524 (17.8%)" "lysine biosynthetic process via diaminopimelate (17.8%) homoserine biosynthetic process (17.8%) threonine biosynthetic process (10.9%)" cytosol (17.8%) "aspartate kinase activity (17.8%) ATP binding (17.8%)" "IPR001048 (14.3%) IPR001341 (14.3%) IPR005260 (14.3%)" "Aspartate/glutamate/uridylate kinase (14.3%) Aspartate kinase (14.3%) Aspartate kinase, monofunctional class (14.3%)" YVAAQQEFDKTGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (32.1%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (32.1%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" TVGLACDHAGFPLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.6 (100%) ribose-5-phosphate isomerase (100%) "GO:0009052 (33.3%) GO:0019316 (33.3%)" GO:0004751 (33.3%) "pentose-phosphate shunt, non-oxidative branch (33.3%) D-allose catabolic process (33.3%)" ribose-5-phosphate isomerase activity (33.3%) "IPR003500 (36.6%) IPR036569 (36.6%) IPR004785 (26.8%)" "Sugar-phosphate isomerase, RpiB/LacA/LacB family (36.6%) Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily (36.6%) Ribose 5-phosphate isomerase B (26.8%)" TKNNPLLLGEPGTGK root "GO:0034605 (20%) GO:0042026 (15.4%) GO:0006508 (2.1%)" "GO:0005737 (20%) GO:0005829 (0%)" "GO:0005524 (20%) GO:0016887 (20%) GO:0008233 (2.1%)" "cellular response to heat (20%) protein refolding (15.4%) proteolysis (2.1%)" "cytoplasm (20%) cytosol (0%)" "ATP binding (20%) ATP hydrolysis activity (20%) peptidase activity (2.1%)" "IPR050130 (8.5%) IPR003593 (8.5%) IPR003959 (8.5%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.5%) AAA+ ATPase domain (8.5%) ATPase, AAA-type, core (8.5%)" LNPTQNLVDAFPAANGYPLTDER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.7%) IPR011990 (32.1%) IPR033985 (32.1%)" "RagB/SusD domain (35.7%) Tetratricopeptide-like helical domain superfamily (32.1%) SusD-like, N-terminal (32.1%)" LLLCEDDENLGMLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006355 (19.9%) GO:0000160 (0.2%)" "GO:0005829 (19.9%) GO:0032993 (19.9%)" "GO:0000156 (19.9%) GO:0000976 (19.9%) GO:0003677 (0.1%)" "regulation of DNA-templated transcription (19.9%) phosphorelay signal transduction system (0.2%)" "cytosol (19.9%) protein-DNA complex (19.9%)" "phosphorelay response regulator activity (19.9%) transcription cis-regulatory region binding (19.9%) DNA binding (0.1%)" "IPR001789 (17.6%) IPR001867 (17.5%) IPR011006 (17.5%)" "Signal transduction response regulator, receiver domain (17.6%) OmpR/PhoB-type DNA-binding domain (17.5%) CheY-like superfamily (17.5%)" ETYVHCFMDGR Bacteria Bacteria 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20%) IPR006124 (20%) IPR011258 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20%) Metalloenzyme (20%) BPG-independent PGAM, N-terminal (20%)" DNFEKDAFMTSLPQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0015031 (25%) GO:0051205 (25%)" GO:0005886 (25%) GO:0032977 (25%) "protein transport (25%) protein insertion into membrane (25%)" plasma membrane (25%) membrane insertase activity (25%) "IPR001708 (17.2%) IPR028053 (17.2%) IPR028055 (17.2%)" "Membrane insertase YidC/ALB3/OXA1/COX18 (17.2%) Membrane insertase YidC, N-terminal (17.2%) Membrane insertase YidC/Oxa/ALB, C-terminal (17.2%)" LGTELPFATETLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR016769 (33.3%) IPR023214 (33.3%) IPR036412 (33.3%)" "Bacteriophage SP01, Orf1 (33.3%) HAD superfamily (33.3%) HAD-like superfamily (33.3%)" QLELESLWSGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003593 (25.2%) IPR003959 (25.2%) IPR051396 (25.2%)" "AAA+ ATPase domain (25.2%) ATPase, AAA-type, core (25.2%) Bacterial Antiviral Defense Nuclease (25.2%)" NNWDLSALR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.97.1.12 (100%) photosystem I (100%) "GO:0016020 (99.1%) GO:0031514 (0.5%)" GO:0016491 (0.5%) "membrane (99.1%) motile cilium (0.5%)" oxidoreductase activity (0.5%) "IPR006665 (33.4%) IPR050330 (33.4%) IPR036737 (33.2%)" "OmpA-like domain (33.4%) Bacterial Outer Membrane Structural/Functional (33.4%) OmpA-like domain superfamily (33.2%)" QLQEVVVSGK root GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (17.1%) IPR057601 (17.1%) IPR008969 (16.4%)" "TonB-dependent receptor-like (17.1%) TonB-dependent transporter Oar-like, beta-barrel domain (17.1%) Carboxypeptidase-like, regulatory domain superfamily (16.4%)" NLVDALHNSADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (37.3%) IPR011990 (33.9%) IPR024302 (28.8%)" "SusD-like 2 (37.3%) Tetratricopeptide-like helical domain superfamily (33.9%) SusD-like (28.8%)" GTPTSPGTASPYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (10.6%) IPR004514 (10.6%) IPR020058 (10.6%)" "Aminoacyl-tRNA synthetase, class I, conserved site (10.6%) Glutamine-tRNA synthetase (10.6%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.6%)" EWVVLDATDQVVGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (20%) GO:0017148 (20%)" GO:0022625 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" cytosolic large ribosomal subunit (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (25%) IPR005823 (25%) IPR023563 (25%)" "Large ribosomal subunit protein uL13 (25%) Large ribosomal subunit protein uL13, bacteria (25%) Large ribosomal subunit protein uL13, conserved site (25%)" TSVEVMDLLK Bacteria Bacteria GO:0005886 (8.3%) "GO:0005524 (45.8%) GO:0016887 (45.8%)" plasma membrane (8.3%) "ATP binding (45.8%) ATP hydrolysis activity (45.8%)" "IPR003439 (19.6%) IPR003593 (19.6%) IPR017871 (19.6%)" "ABC transporter-like, ATP-binding domain (19.6%) AAA+ ATPase domain (19.6%) ABC transporter-like, conserved site (19.6%)" NLLHVQVFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.99.1.3 (100%) Transferred entry: 5.6.2.2 (100%) GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.5%) IPR050220 (20.5%) IPR013757 (19.7%)" "DNA topoisomerase, type IIA, domain A (20.5%) Type II DNA Topoisomerases (20.5%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.7%)" LKELGAQGLLVTPLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" AFVDNYHLYYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR019847 (100%) Gliding motility associated protein GldN (100%) NAFAHSSGLHQDGVLK root 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) "GO:0009098 (25.5%) GO:0006099 (0%) GO:0006260 (0%)" "GO:0005737 (9.1%) GO:0005829 (7.1%)" "GO:0003852 (25.5%) GO:0003985 (16%) GO:0030145 (16%)" "L-leucine biosynthetic process (25.5%) tricarboxylic acid cycle (0%) DNA replication (0%)" "cytoplasm (9.1%) cytosol (7.1%)" "2-isopropylmalate synthase activity (25.5%) acetyl-CoA C-acetyltransferase activity (16%) manganese ion binding (16%)" "IPR050073 (14.4%) IPR054691 (14.4%) IPR000891 (14.3%)" "2-IPM synthase/homocitrate synthase-like (14.4%) 2-isopropylmalate synthase/homocitrate synthase, post-catalytic domain (14.4%) Pyruvate carboxyltransferase (14.3%)" LALDQLHLLGDLYDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (50.8%) IPR029052 (49.2%)" "Fructose-1,6-bisphosphatase class 3 (50.8%) Metallo-dependent phosphatase-like (49.2%)" LYFDELSFER root "6.3.5.5 (79.7%) 6.3.4.16 (20.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (79.7%) carbamoyl-phosphate synthase (ammonia) (20.3%)" "GO:0006541 (13.8%) GO:0006526 (11.7%) GO:0006221 (11.6%)" "GO:0005737 (13.8%) GO:0005951 (0.2%) GO:0005739 (0%)" "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (13.9%)" "glutamine metabolic process (13.8%) L-arginine biosynthetic process (11.7%) pyrimidine nucleotide biosynthetic process (11.6%)" "cytoplasm (13.8%) carbamoyl-phosphate synthase complex (0.2%) mitochondrion (0%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (13.9%)" "IPR005480 (10%) IPR016185 (10%) IPR005479 (10%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%) Pre-ATP-grasp domain superfamily (10%) Carbamoyl phosphate synthase, ATP-binding domain (10%)" AGGTEYLFSNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005615 (80%) GO:0005737 (10%) GO:0005886 (10%)" "extracellular space (80%) cytoplasm (10%) plasma membrane (10%)" "IPR001611 (16.3%) IPR027899 (16.3%) IPR041403 (16.3%)" "Leucine-rich repeat (16.3%) Domain of unknown function DUF4458 (16.3%) DUF4458 domain-containing protein, leucine-rich repeat (16.3%)" YTDEVTGLQMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" NTSYELFYNALDLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (20%) GO:0015935 (20%) "GO:0000049 (20%) GO:0003735 (20%) GO:0019843 (20%)" translation (20%) small ribosomal subunit (20%) "tRNA binding (20%) structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" YAGTELEFDGTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005737 (16.7%) "GO:0005524 (16.7%) GO:0044183 (16.7%) GO:0046872 (16.7%)" cytoplasm (16.7%) "ATP binding (16.7%) protein folding chaperone (16.7%) metal ion binding (16.7%)" "IPR011032 (33.3%) IPR020818 (33.3%) IPR037124 (33.3%)" "GroES-like superfamily (33.3%) GroES chaperonin family (33.3%) GroES chaperonin superfamily (33.3%)" HFLSVENVK Bacteria Bacteria 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (24.5%) GO:0030203 (24.5%)" GO:0016020 (24.5%) "GO:0004563 (24.5%) GO:0003676 (1.1%) GO:0004523 (1.1%)" "carbohydrate metabolic process (24.5%) glycosaminoglycan metabolic process (24.5%)" membrane (24.5%) "beta-N-acetylhexosaminidase activity (24.5%) nucleic acid binding (1.1%) RNA-DNA hybrid ribonuclease activity (1.1%)" "IPR011658 (17.2%) IPR015883 (17.2%) IPR025705 (17.2%)" "PA14 domain (17.2%) Glycoside hydrolase family 20, catalytic domain (17.2%) Beta-hexosaminidase (17.2%)" YALALADK root "1.4.1.1 (62.6%) 2.3.1.180 (13%) 3.5.4.33 (9.2%)" "alanine dehydrogenase (62.6%) beta-ketoacyl-[acyl-carrier-protein] synthase III (13%) tRNA(adenine(34)) deaminase (9.2%)" "GO:0042853 (14.3%) GO:0006633 (3.2%) GO:0006420 (2.6%)" "GO:0005886 (14.7%) GO:0005737 (5.3%) GO:0005829 (1.4%)" "GO:0000286 (14.5%) GO:0000166 (12.3%) GO:0004315 (3.2%)" "L-alanine catabolic process (14.3%) fatty acid biosynthetic process (3.2%) arginyl-tRNA aminoacylation (2.6%)" "plasma membrane (14.7%) cytoplasm (5.3%) cytosol (1.4%)" "alanine dehydrogenase activity (14.5%) nucleotide binding (12.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (3.2%)" "IPR007698 (11.6%) IPR007886 (11.4%) IPR008141 (11.4%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (11.6%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (11.4%) Alanine dehydrogenase (11.4%)" MEVSVLDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" AAYAEESFYVGADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005840 (51.4%) GO:1990904 (48.6%)" "ribosome (51.4%) ribonucleoprotein complex (48.6%)" "IPR001790 (34%) IPR047865 (34%) IPR043141 (32.1%)" "Large ribosomal subunit protein uL10 (34%) Large ribosomal subunit protein uL10, bacteria/organella (34%) Large ribosomal subunit protein uL10-like domain superfamily (32.1%)" QVQQNFNNHWSLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.2%) GO:0009252 (11.2%) GO:0071555 (11.2%)" "GO:0030288 (11.2%) GO:0005886 (10.9%) GO:0016020 (0.4%)" "GO:0008955 (11.2%) GO:0004180 (10.9%) GO:0008658 (10.9%)" "regulation of cell shape (11.2%) peptidoglycan biosynthetic process (11.2%) cell wall organization (11.2%)" "outer membrane-bounded periplasmic space (11.2%) plasma membrane (10.9%) membrane (0.4%)" "peptidoglycan glycosyltransferase activity (11.2%) carboxypeptidase activity (10.9%) penicillin binding (10.9%)" "IPR001264 (17%) IPR050396 (17%) IPR001460 (16.5%)" "Glycosyl transferase, family 51 (17%) Glycosyltransferase 51/Transpeptidase (17%) Penicillin-binding protein, transpeptidase (16.5%)" GYTVDQLHDLTK root "6.3.5.5 (79.5%) 6.3.4.16 (20.5%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (79.5%) carbamoyl-phosphate synthase (ammonia) (20.5%)" "GO:0006526 (13%) GO:0006541 (11.6%) GO:0006221 (10.3%)" "GO:0005737 (12.5%) GO:0005739 (2.3%) GO:0005951 (0.5%)" "GO:0005524 (15%) GO:0046872 (15%) GO:0004088 (14.8%)" "L-arginine biosynthetic process (13%) glutamine metabolic process (11.6%) pyrimidine nucleotide biosynthetic process (10.3%)" "cytoplasm (12.5%) mitochondrion (2.3%) carbamoyl-phosphate synthase complex (0.5%)" "ATP binding (15%) metal ion binding (15%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.8%)" "IPR005480 (10.4%) IPR005479 (10.2%) IPR011761 (10.2%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.4%) Carbamoyl phosphate synthase, ATP-binding domain (10.2%) ATP-grasp fold (10.2%)" YESEYTMTTANSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" HVDYSTVGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR036709 (50%) IPR027385 (33.3%) IPR011250 (16.7%)" "Autotransporter beta-domain superfamily (50%) Outer membrane protein, beta-barrel domain (33.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16.7%)" DYGQLLAAELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.7%) IPR002890 (19.7%) IPR051802 (19.7%)" "Alpha-2-macroglobulin (19.7%) Macroglobulin domain (19.7%) Alpha-2-macroglobulin-like (19.7%)" TAAYLLPVLSK root "3.6.4.13 (87.5%) 3.6.4.- (12.5%)" "RNA helicase (87.5%) Acting on ATP; involved in cellular and subcellular movement (12.5%)" GO:0005829 (19%) "GO:0003676 (20.2%) GO:0003724 (20.2%) GO:0005524 (20.2%)" cytosol (19%) "nucleic acid binding (20.2%) RNA helicase activity (20.2%) ATP binding (20.2%)" "IPR001650 (14.5%) IPR011545 (14.5%) IPR014001 (14.5%)" "Helicase, C-terminal domain-like (14.5%) DEAD/DEAH-box helicase domain (14.5%) Helicase superfamily 1/2, ATP-binding domain (14.5%)" AATGMPAAASFK Bacteria Bacteria "2.1.2.3 (95.7%) 3.5.4.10 (4.3%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (95.7%) IMP cyclohydrolase (4.3%)" GO:0006189 (25%) GO:0005829 (25%) "GO:0003937 (25%) GO:0004643 (25%)" 'de novo' IMP biosynthetic process (25%) cytosol (25%) "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%)" "IPR002695 (26.3%) IPR016193 (24.6%) IPR024050 (24.6%)" "Bifunctional purine biosynthesis protein PurH-like (26.3%) Cytidine deaminase-like (24.6%) AICAR transformylase, insert domain superfamily (24.6%)" LDFVLHSVAMSPNVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (34.1%) IPR014358 (34.1%) IPR036291 (31.8%)" "Short-chain dehydrogenase/reductase SDR (34.1%) Enoyl-[acyl-carrier-protein] reductase (NADH) (34.1%) NAD(P)-binding domain superfamily (31.8%)" FAPSPTGALHLGGVR Bacteria Bacteria 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) "GO:0005829 (16.7%) GO:0005737 (0%)" "GO:0004818 (16.7%) GO:0005524 (16.7%) GO:0008270 (16.6%)" glutamyl-tRNA aminoacylation (16.7%) "cytosol (16.7%) cytoplasm (0%)" "glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%) zinc ion binding (16.6%)" "IPR001412 (9.7%) IPR020058 (9.7%) IPR049940 (9.7%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.7%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (9.7%) Glutamyl-Q tRNA(Asp) synthetase/Glutamate--tRNA ligase (9.7%)" VLGTFEDLTASVPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0002181 (19.9%) "GO:0015934 (19.9%) GO:0005840 (0.4%)" "GO:0003735 (19.9%) GO:0016740 (19.9%) GO:0019843 (19.9%)" cytoplasmic translation (19.9%) "large ribosomal subunit (19.9%) ribosome (0.4%)" "structural constituent of ribosome (19.9%) transferase activity (19.9%) rRNA binding (19.9%)" "IPR012340 (11.3%) IPR002171 (11.1%) IPR005880 (11.1%)" "Nucleic acid-binding, OB-fold (11.3%) Large ribosomal subunit protein uL2 (11.1%) Large ribosomal subunit protein uL2, bacteria/organella (11.1%)" NYGLLWDSYSYCR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.- (75%) 3.2.1.177 (25%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (75%) alpha-D-xyloside xylohydrolase (25%)" GO:0005975 (33.8%) "GO:0004553 (33.8%) GO:0030246 (32.4%)" carbohydrate metabolic process (33.8%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.8%) carbohydrate binding (32.4%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" YLDEVMGK root 2.7.7.65 (100%) diguanylate cyclase (100%) "GO:0043709 (20%) GO:1902201 (20%)" GO:0005886 (20%) "GO:0003824 (20%) GO:0052621 (20%)" "cell adhesion involved in single-species biofilm formation (20%) negative regulation of bacterial-type flagellum-dependent cell motility (20%)" plasma membrane (20%) "catalytic activity (20%) diguanylate cyclase activity (20%)" "IPR027848 (67.7%) IPR000160 (3.2%) IPR000477 (3.2%)" "Protein of unknown function DUF4494 (67.7%) GGDEF domain (3.2%) Reverse transcriptase domain (3.2%)" EVTYEGYGPHGVAVFVDTLTDNTTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006355 (32.2%) GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0016779 (1.1%)" regulation of DNA-templated transcription (32.2%) cytosol (33.3%) "DNA binding (33.3%) nucleotidyltransferase activity (1.1%)" "IPR002876 (16.9%) IPR048300 (16.9%) IPR049083 (16.9%)" "Transcriptional regulator TACO1-like (16.9%) TACO1/YebC-like, second and third domains (16.9%) TACO1/YebC-like, N-terminal domain (16.9%)" FEDGGYGFDYR Bacteria Bacteria 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (19.2%) GO:0005975 (1.1%)" GO:0005737 (20.3%) "GO:0003844 (20.3%) GO:0004553 (19.6%) GO:0043169 (19.6%)" "glycogen biosynthetic process (19.2%) carbohydrate metabolic process (1.1%)" cytoplasm (20.3%) "1,4-alpha-glucan branching enzyme activity (20.3%) hydrolase activity, hydrolyzing O-glycosyl compounds (19.6%) cation binding (19.6%)" "IPR017853 (12.8%) IPR004193 (12.6%) IPR006047 (12.6%)" "Glycoside hydrolase superfamily (12.8%) Glycoside hydrolase, family 13, N-terminal (12.6%) Glycosyl hydrolase family 13, catalytic domain (12.6%)" LVVLEEVENAPYFGDRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.65 (100%) phosphatidylserine decarboxylase (100%) GO:0006646 (33.3%) GO:0005886 (33.3%) GO:0004609 (33.3%) phosphatidylethanolamine biosynthetic process (33.3%) plasma membrane (33.3%) phosphatidylserine decarboxylase activity (33.3%) "IPR003817 (50%) IPR033175 (50%)" "Phosphatidylserine decarboxylase-related (50%) Phosphatidylserine decarboxylase, prokaryotes (50%)" NQQMDDHYFGALPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (49.2%) GO:0004356 (50.8%) glutamine biosynthetic process (49.2%) glutamine synthetase activity (50.8%) "IPR008146 (14.5%) IPR027303 (14.5%) IPR040577 (14.5%)" "Glutamine synthetase, catalytic domain (14.5%) Glutamine synthetase, glycine-rich site (14.5%) Glutamine synthetase, C-terminal (14.5%)" TPVEYDEVTPDFFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.4%) GO:0016020 (0.9%)" "GO:0008658 (11.3%) GO:0008955 (11.3%) GO:0004180 (10.4%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.4%) membrane (0.9%)" "penicillin binding (11.3%) peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.4%)" "IPR001264 (17.3%) IPR001460 (17.3%) IPR050396 (17.3%)" "Glycosyl transferase, family 51 (17.3%) Penicillin-binding protein, transpeptidase (17.3%) Glycosyltransferase 51/Transpeptidase (17.3%)" VTVNFQGETLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.7%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.7%) "IPR028994 (18%) IPR003284 (16.3%) IPR022045 (13.5%)" "Integrin alpha, N-terminal (18%) Salmonella virulence plasmid 65kDa B protein (16.3%) Insecticide toxin TcdB middle/N-terminal (13.5%)" WSPSSYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.1.1.144 (66.7%) 3.4.-.- (33.3%)" "trans-aconitate 2-methyltransferase (66.7%) Acting on peptide bonds (peptidases) (33.3%)" "GO:0006508 (45.7%) GO:0032259 (2.9%)" GO:0005737 (2.9%) "GO:0004252 (45.7%) GO:0030798 (2.9%)" "proteolysis (45.7%) methylation (2.9%)" cytoplasm (2.9%) "serine-type endopeptidase activity (45.7%) trans-aconitate 2-methyltransferase activity (2.9%)" "IPR001375 (19.3%) IPR002469 (19.3%) IPR011659 (19.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (19.3%) Dipeptidylpeptidase IV, N-terminal domain (19.3%) WD40-like beta-propeller (19.3%)" TFLQEVLFFPQMKPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.8%) GO:0005829 (16.8%) "GO:0000049 (16.8%) GO:0004824 (16.8%) GO:0005524 (16.8%)" lysyl-tRNA aminoacylation (16.8%) cytosol (16.8%) "tRNA binding (16.8%) lysine-tRNA ligase activity (16.8%) ATP binding (16.8%)" "IPR004364 (13%) IPR006195 (13%) IPR002313 (12.6%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (13%) Aminoacyl-tRNA synthetase, class II (13%) Lysine-tRNA ligase, class II (12.6%)" AGLGYLPQEASVFR root "3.6.3.- (92.3%) 3.6.3.25 (7.7%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (92.3%) Transferred entry: 7.3.2.3 (7.7%)" "GO:0055085 (22.2%) GO:0006352 (0.4%) GO:0006417 (0.2%)" "GO:0043190 (22.6%) GO:0005737 (4.8%) GO:0000428 (0.4%)" "GO:0005524 (22.8%) GO:0016887 (22.8%) GO:0001216 (0.4%)" "transmembrane transport (22.2%) DNA-templated transcription initiation (0.4%) regulation of translation (0.2%)" "ATP-binding cassette (ABC) transporter complex (22.6%) cytoplasm (4.8%) DNA-directed RNA polymerase complex (0.4%)" "ATP binding (22.8%) ATP hydrolysis activity (22.8%) DNA-binding transcription activator activity (0.4%)" "IPR003439 (17%) IPR003593 (16.8%) IPR027417 (16.8%)" "ABC transporter-like, ATP-binding domain (17%) AAA+ ATPase domain (16.8%) P-loop containing nucleoside triphosphate hydrolase (16.8%)" ELQSVGLQPDLLLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (11.8%) GO:0044210 (11.8%)" "GO:0005829 (11.8%) GO:0097268 (11.8%)" "GO:0003883 (11.8%) GO:0005524 (11.8%) GO:0042802 (11.8%)" "pyrimidine nucleobase biosynthetic process (11.8%) 'de novo' CTP biosynthetic process (11.8%)" "cytosol (11.8%) cytoophidium (11.8%)" "CTP synthase activity (11.8%) ATP binding (11.8%) identical protein binding (11.8%)" "IPR004468 (16.9%) IPR017456 (16.9%) IPR017926 (16.9%)" "CTP synthase (16.9%) CTP synthase, N-terminal (16.9%) Glutamine amidotransferase (16.9%)" NVQGFGSANPVVNTTAACAQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (91.7%) GO:0016020 (8.3%)" "cell outer membrane (91.7%) membrane (8.3%)" "IPR006665 (20.7%) IPR027367 (20.7%) IPR050330 (20.7%)" "OmpA-like domain (20.7%) YMGG-like Gly-zipper (20.7%) Bacterial Outer Membrane Structural/Functional (20.7%)" SKHELTADQLAAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR033427 (43.5%) IPR011050 (39.1%) IPR012334 (17.4%)" "Domain of unknown function DUF5123 (43.5%) Pectin lyase fold/virulence factor (39.1%) Pectin lyase fold (17.4%)" AASLNMPYVNER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" TSSSDKDAYQGLSGTTVNHYSHEGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (27.8%) GO:0009279 (44.4%) GO:0015344 (27.8%) siderophore transmembrane transport (27.8%) cell outer membrane (44.4%) siderophore uptake transmembrane transporter activity (27.8%) "IPR000531 (45.8%) IPR036942 (33.3%) IPR039426 (20.8%)" "TonB-dependent receptor-like, beta-barrel (45.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (33.3%) TonB-dependent receptor-like (20.8%)" LHELYGSWADQVLSLYPAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.3%) IPR019826 (20.3%) IPR050309 (20.3%)" "Carboxylesterase, type B (20.3%) Carboxylesterase type B, active site (20.3%) Type-B Carboxylesterase/Lipase (20.3%)" NGAVSDLDGNYKLDNVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13%) IPR012910 (13%) IPR037066 (13%)" "Carboxypeptidase-like, regulatory domain superfamily (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent receptor, plug domain superfamily (13%)" NEDLFQYNTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.- (66.7%) 3.2.1.177 (33.3%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (66.7%) alpha-D-xyloside xylohydrolase (33.3%)" GO:0005975 (33.7%) "GO:0004553 (33.2%) GO:0030246 (32.6%) GO:0061634 (0.5%)" carbohydrate metabolic process (33.7%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.2%) carbohydrate binding (32.6%) alpha-D-xyloside xylohydrolase (0.5%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" HSFTAMLGQEAWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR039426 (14.8%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent receptor-like (14.8%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" AVPLYQTTSYVFR root "2.5.1.49 (65.3%) 4.4.1.11 (24.5%) 2.5.1.47 (5.1%)" "O-acetylhomoserine aminocarboxypropyltransferase (65.3%) methionine gamma-lyase (24.5%) cysteine synthase (5.1%)" "GO:0019346 (13.8%) GO:0071269 (13.8%) GO:0006535 (13.7%)" GO:0005737 (13.7%) "GO:0004124 (13.8%) GO:0030170 (13.8%) GO:0003961 (13.7%)" "transsulfuration (13.8%) L-homocysteine biosynthetic process (13.8%) cysteine biosynthetic process from serine (13.7%)" cytoplasm (13.7%) "cysteine synthase activity (13.8%) pyridoxal phosphate binding (13.8%) O-acetylhomoserine aminocarboxypropyltransferase activity (13.7%)" "IPR000277 (16.8%) IPR006235 (16.8%) IPR015421 (16.8%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (16.8%) O-acetylhomoserine/O-acetylserine sulfhydrylase (16.8%) Pyridoxal phosphate-dependent transferase, major domain (16.8%)" VNVGFHWFDDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (90.9%) IPR011250 (9.1%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (90.9%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (9.1%)" LLHLDLDKAELDK Bacteria Bacteria 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR012000 (13.3%) IPR045229 (13.3%) IPR011766 (12.6%)" "Thiamine pyrophosphate enzyme, central domain (13.3%) Thiamine pyrophosphate enzyme (13.3%) Thiamine pyrophosphate enzyme, TPP-binding (12.6%)" EMVSNAVDATQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (0.2%) "GO:0005524 (24.5%) GO:0016887 (24.5%) GO:0051082 (24.5%)" cytoplasm (0.2%) "ATP binding (24.5%) ATP hydrolysis activity (24.5%) unfolded protein binding (24.5%)" "IPR001404 (18.5%) IPR020575 (18.5%) IPR036890 (18.3%)" "Heat shock protein Hsp90 family (18.5%) Heat shock protein Hsp90, N-terminal (18.5%) Histidine kinase/HSP90-like ATPase superfamily (18.3%)" VCYKDNLVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.8%) GO:0005829 (32.8%) "GO:0008926 (32.8%) GO:0009026 (1.7%)" mannitol catabolic process (32.8%) cytosol (32.8%) "mannitol-1-phosphate 5-dehydrogenase activity (32.8%) tagaturonate reductase activity (1.7%)" "IPR013118 (21.3%) IPR013131 (21.3%) IPR008927 (19.1%)" "Mannitol dehydrogenase, C-terminal (21.3%) Mannitol dehydrogenase, N-terminal (21.3%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (19.1%)" SGYGHGYTFPCLFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.22 (100%) alpha-galactosidase (100%) "GO:0030246 (49%) GO:0016798 (43.1%) GO:0004557 (3.9%)" "carbohydrate binding (49%) hydrolase activity, acting on glycosyl bonds (43.1%) alpha-galactosidase activity (3.9%)" "IPR029486 (12.9%) IPR052720 (12.9%) IPR019563 (12.7%)" "Glycosyl-hydrolase 97, N-terminal domain (12.9%) Glycosyl Hydrolase Family 97 (12.9%) Glycosyl-hydrolase 97, catalytic domain (12.7%)" KLTHQFQGVLTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.4 (100%) glutamate dehydrogenase (NADP(+)) (100%) GO:0006537 (25.5%) GO:0005829 (25.5%) "GO:0004354 (25.5%) GO:0000166 (23.6%)" glutamate biosynthetic process (25.5%) cytosol (25.5%) "glutamate dehydrogenase (NADP+) activity (25.5%) nucleotide binding (23.6%)" "IPR006095 (11.2%) IPR006096 (11.2%) IPR006097 (11.2%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.2%)" NANNSNFEYVVAGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NPEGANEVLNNLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.6%) GO:0009090 (17.6%) GO:0009088 (12%)" GO:0005829 (17.6%) "GO:0004072 (17.6%) GO:0005524 (17.6%)" "lysine biosynthetic process via diaminopimelate (17.6%) homoserine biosynthetic process (17.6%) threonine biosynthetic process (12%)" cytosol (17.6%) "aspartate kinase activity (17.6%) ATP binding (17.6%)" "IPR001048 (14.4%) IPR001341 (14.4%) IPR005260 (14.4%)" "Aspartate/glutamate/uridylate kinase (14.4%) Aspartate kinase (14.4%) Aspartate kinase, monofunctional class (14.4%)" EMGEGCYYPDLSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006004 (33.3%) GO:0005737 (33.3%) GO:0008736 (33.3%) fucose metabolic process (33.3%) cytoplasm (33.3%) L-fucose isomerase activity (33.3%) "IPR015888 (51.3%) IPR009015 (48.7%)" "L-fucose isomerase, C-terminal (51.3%) L-fucose isomerase, N-terminal/central domain superfamily (48.7%)" MSEYGVMLAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (19.6%) GO:0042274 (19.6%)" "GO:0015935 (19.6%) GO:0005840 (1%)" "GO:0019843 (20.6%) GO:0003735 (19.6%)" "translation (19.6%) ribosomal small subunit biogenesis (19.6%)" "small ribosomal subunit (19.6%) ribosome (1%)" "rRNA binding (20.6%) structural constituent of ribosome (19.6%)" "IPR001912 (17.2%) IPR036986 (17.2%) IPR002942 (16.4%)" "Small ribosomal subunit protein uS4, N-terminal (17.2%) RNA-binding S4 domain superfamily (17.2%) RNA-binding S4 domain (16.4%)" KYGFGLSDFDGLPNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TAWNPNSYKFETPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.1%) "GO:0004553 (34.1%) GO:0030246 (31.7%)" carbohydrate metabolic process (34.1%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.1%) carbohydrate binding (31.7%)" "IPR000322 (11.4%) IPR025887 (11.4%) IPR033403 (11.4%)" "Glycoside hydrolase family 31, TIM barrel domain (11.4%) Glycoside hydrolase family 31, N-terminal domain (11.4%) Domain of unknown function DUF5110 (11.4%)" GVDMFDCVMPTR root "2.4.2.29 (99.5%) 2.4.2.64 (0.3%) 2.4.2.- (0.2%)" "tRNA-guanosine(34) preQ1 transglycosylase (99.5%) tRNA-guanosine(34) queuine transglycosylase (0.3%) Pentosyltransferases (0.2%)" "GO:0002099 (24.6%) GO:0008616 (2.1%) GO:0006400 (1.6%)" "GO:0005829 (26.2%) GO:0005737 (0.1%) GO:0016020 (0%)" "GO:0008479 (26.1%) GO:0046872 (18.4%) GO:0016757 (0.2%)" "tRNA wobble guanine modification (24.6%) tRNA queuosine(34) biosynthetic process (2.1%) tRNA modification (1.6%)" "cytosol (26.2%) cytoplasm (0.1%) membrane (0%)" "tRNA-guanosine(34) queuine transglycosylase activity (26.1%) metal ion binding (18.4%) glycosyltransferase activity (0.2%)" "IPR002616 (25.4%) IPR036511 (25.4%) IPR004803 (25.2%)" "tRNA-guanine(15) transglycosylase-like (25.4%) Queuine tRNA-ribosyltransferase-like (25.4%) tRNA-guanine transglycosylase (25.2%)" FTYDGMAAWQYQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023997 (14.7%) IPR037066 (14.7%) IPR039426 (14.7%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%) TonB-dependent receptor, plug domain superfamily (14.7%) TonB-dependent receptor-like (14.7%)" DVTGDGLVSASDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" MDFLGLK root "2.7.7.7 (98.6%) 2.7.2.1 (0.6%) 3.2.1.52 (0.1%)" "DNA-directed DNA polymerase (98.6%) acetate kinase (0.6%) beta-N-acetylhexosaminidase (0.1%)" "GO:0006260 (22.7%) GO:0016539 (0.8%) GO:0055085 (0.2%)" "GO:0005737 (10.5%) GO:0005886 (0.4%) GO:0016020 (0.3%)" "GO:0008408 (22.7%) GO:0003887 (22.6%) GO:0003676 (16%)" "DNA replication (22.7%) intein-mediated protein splicing (0.8%) transmembrane transport (0.2%)" "cytoplasm (10.5%) plasma membrane (0.4%) membrane (0.3%)" "3'-5' exonuclease activity (22.7%) DNA-directed DNA polymerase activity (22.6%) nucleic acid binding (16%)" "IPR004805 (10.5%) IPR011708 (10.4%) IPR040982 (10.4%)" "Error-prone DNA polymerase/DNA polymerase III subunit alpha DnaE/PolC (10.5%) Bacterial DNA polymerase III, alpha subunit, NTPase domain (10.4%) DNA polymerase III alpha subunit finger domain (10.4%)" LGLNGFGR root "1.2.1.- (67.2%) 1.2.1.12 (31.3%) 1.2.1.59 (0.9%)" "With NAD(+) or NADP(+) as acceptor (67.2%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (31.3%) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating) (0.9%)" "GO:0006006 (17.2%) GO:0006096 (9.7%) GO:0019682 (1.5%)" "GO:0005829 (8.3%) GO:0005737 (2.4%) GO:0032991 (0.9%)" "GO:0051287 (18.2%) GO:0050661 (17.3%) GO:0004365 (12.9%)" "glucose metabolic process (17.2%) glycolytic process (9.7%) glyceraldehyde-3-phosphate metabolic process (1.5%)" "cytosol (8.3%) cytoplasm (2.4%) protein-containing complex (0.9%)" "NAD binding (18.2%) NADP binding (17.3%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (12.9%)" "IPR020828 (17.2%) IPR036291 (17.1%) IPR020831 (17.1%)" "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (17.2%) NAD(P)-binding domain superfamily (17.1%) Glyceraldehyde/Erythrose phosphate dehydrogenase family (17.1%)" EYDHELNDEELR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (8.1%) IPR012162 (8.1%) IPR015847 (8.1%)" "Exoribonuclease, phosphorolytic domain 1 (8.1%) Polyribonucleotide nucleotidyltransferase (8.1%) Exoribonuclease, phosphorolytic domain 2 (8.1%)" KFLELVEAR Bacteria Bacteria "GO:0043093 (32.5%) GO:0051301 (0.8%)" "GO:0009898 (33.3%) GO:0032153 (33.3%)" "FtsZ-dependent cytokinesis (32.5%) cell division (0.8%)" "cytoplasmic side of plasma membrane (33.3%) cell division site (33.3%)" "IPR050696 (25.5%) IPR003494 (24.8%) IPR020823 (24.8%)" "Bacterial cell division protein FtsA/MreB (25.5%) SHS2 domain inserted in FtsA (24.8%) Cell division protein FtsA (24.8%)" VVHVTNLNDSGTGSFR Bacteria Bacteria 4.2.2.2 (100%) pectate lyase (100%) "GO:0000272 (3.6%) GO:0071555 (3.6%)" "GO:0016829 (67.9%) GO:0004557 (17.9%) GO:0004553 (3.6%)" "polysaccharide catabolic process (3.6%) cell wall organization (3.6%)" "lyase activity (67.9%) alpha-galactosidase activity (17.9%) hydrolase activity, hydrolyzing O-glycosyl compounds (3.6%)" "IPR052063 (32.3%) IPR011050 (29%) IPR012334 (29%)" "Polysaccharide Lyase 1 (32.3%) Pectin lyase fold/virulence factor (29%) Pectin lyase fold (29%)" DCTWEQLEEVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (20%) GO:0005829 (20%) "GO:0004335 (20%) GO:0005524 (20%) GO:0046872 (20%)" galactose metabolic process (20%) cytosol (20%) "galactokinase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000705 (10.3%) IPR006203 (10.3%) IPR006204 (10.3%)" "Galactokinase (10.3%) GHMP kinase, ATP-binding, conserved site (10.3%) GHMP kinase N-terminal domain (10.3%)" LLDQQLDMYAQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.8%) GO:0043335 (15.8%) GO:0051083 (15.8%)" GO:0005737 (5%) "GO:0003755 (15.8%) GO:0043022 (15.8%) GO:0044183 (15.8%)" "protein transport (15.8%) protein unfolding (15.8%) 'de novo' cotranslational protein folding (15.8%)" cytoplasm (5%) "peptidyl-prolyl cis-trans isomerase activity (15.8%) ribosome binding (15.8%) protein folding chaperone (15.8%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR027304 (18.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor/SurA domain superfamily (18.4%)" AQVPLLLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (80%) GO:0005737 (10%) GO:0005886 (10%)" "extracellular space (80%) cytoplasm (10%) plasma membrane (10%)" "IPR001611 (16.2%) IPR027899 (16.2%) IPR041403 (16.2%)" "Leucine-rich repeat (16.2%) Domain of unknown function DUF4458 (16.2%) DUF4458 domain-containing protein, leucine-rich repeat (16.2%)" LDLEGEPVLQAVAENVVETQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0009245 (14.7%) GO:0006633 (14%)" "GO:0016020 (14.7%) GO:0005737 (14%)" "GO:0103117 (14.7%) GO:0046872 (14%) GO:0016836 (10%)" "lipid A biosynthetic process (14.7%) fatty acid biosynthetic process (14%)" "membrane (14.7%) cytoplasm (14%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.7%) metal ion binding (14%) hydro-lyase activity (10%)" "IPR004463 (15.1%) IPR010084 (14.4%) IPR013114 (14.4%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (15.1%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.4%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.4%)" VELAPEDFR root 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006384 (16.6%) GO:0006265 (7.5%) GO:0006261 (6.7%)" "GO:0005666 (16.6%) GO:0005694 (6.7%) GO:0005737 (6.7%)" "GO:0003677 (7.5%) GO:0005524 (7.5%) GO:0034335 (6.7%)" "transcription initiation at RNA polymerase III promoter (16.6%) DNA topological change (7.5%) DNA-templated DNA replication (6.7%)" "RNA polymerase III complex (16.6%) chromosome (6.7%) cytoplasm (6.7%)" "DNA binding (7.5%) ATP binding (7.5%) DNA negative supercoiling activity (6.7%)" "IPR005576 (9.4%) IPR012340 (9.4%) IPR013238 (9.4%)" "RNA polymerase Rpb7-like , N-terminal (9.4%) Nucleic acid-binding, OB-fold (9.4%) RNA polymerase III, subunit Rpc25 (9.4%)" STGAQYVLLGHSER Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (13.9%) GO:0006096 (13.9%) GO:0019563 (13.9%)" "GO:0005829 (13.9%) GO:0016020 (8.3%)" GO:0004807 (13.9%) "gluconeogenesis (13.9%) glycolytic process (13.9%) glycerol catabolic process (13.9%)" "cytosol (13.9%) membrane (8.3%)" triose-phosphate isomerase activity (13.9%) "IPR000652 (18.1%) IPR020861 (18%) IPR022896 (17.9%)" "Triosephosphate isomerase (18.1%) Triosephosphate isomerase, active site (18%) Triosephosphate isomerase, bacterial/eukaryotic (17.9%)" ATGSYQNNLWVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" SLFPVFCVCAGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (7.8%) IPR005225 (7.8%) IPR041095 (7.8%)" "Translational (tr)-type GTP-binding domain (7.8%) Small GTP-binding domain (7.8%) Elongation Factor G, domain II (7.8%)" AGEPLTLR root "1.8.1.2 (39.6%) 6.3.4.14 (20.8%) 5.6.2.1 (6.3%)" "assimilatory sulfite reductase (NADPH) (39.6%) biotin carboxylase (20.8%) DNA topoisomerase (6.3%)" "GO:0000103 (4.7%) GO:0019344 (4.7%) GO:0070814 (4.7%)" "GO:0016020 (9.7%) GO:0009337 (4.7%) GO:0005737 (1.2%)" "GO:0046872 (9.2%) GO:0005524 (5%) GO:0051539 (5%)" "sulfate assimilation (4.7%) cysteine biosynthetic process (4.7%) hydrogen sulfide biosynthetic process (4.7%)" "membrane (9.7%) sulfite reductase complex (NADPH) (4.7%) cytoplasm (1.2%)" "metal ion binding (9.2%) ATP binding (5%) 4 iron, 4 sulfur cluster binding (5%)" "IPR025738 (5.4%) IPR011990 (5.2%) IPR019734 (5.2%)" "Aerotolerance-related protein BatD (5.4%) Tetratricopeptide-like helical domain superfamily (5.2%) Tetratricopeptide repeat (5.2%)" TVFEHSPWAFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (50%) GO:0022857 (50%) plasma membrane (50%) transmembrane transporter activity (50%) "IPR011701 (35%) IPR050375 (35%) IPR036259 (30%)" "Major facilitator superfamily (35%) Major Facilitator Superfamily TsgA-like (35%) MFS transporter superfamily (30%)" HPYDMYDKVEWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" LTNPQLFWSTSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae SALETMNSAEMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" SPTLLPLADEEWCSLHTVLDEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" VAGLYQSQDQLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VLFCCGETLEER Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.8%) GO:0006096 (12.8%) GO:0019563 (12.8%)" "GO:0005829 (12.8%) GO:0016020 (11.9%)" GO:0004807 (12.8%) "gluconeogenesis (12.8%) glycolytic process (12.8%) glycerol catabolic process (12.8%)" "cytosol (12.8%) membrane (11.9%)" triose-phosphate isomerase activity (12.8%) "IPR000652 (17.2%) IPR020861 (17.2%) IPR022896 (17%)" "Triosephosphate isomerase (17.2%) Triosephosphate isomerase, active site (17.2%) Triosephosphate isomerase, bacterial/eukaryotic (17%)" EWSDKDLTNLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (9.3%) IPR006103 (9.3%) IPR006104 (9.3%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.3%) Glycoside hydrolase family 2, catalytic domain (9.3%) Glycosyl hydrolases family 2, sugar binding domain (9.3%)" VGDKVEVYVENQEDVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" SFDQLDNAPEEK root 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (15.2%) GO:0032045 (12.1%)" "GO:0003746 (15.3%) GO:0003924 (15.3%) GO:0005525 (15.3%)" "cytosol (15.2%) guanyl-nucleotide exchange factor complex (12.1%)" "translation elongation factor activity (15.3%) GTPase activity (15.3%) GTP binding (15.3%)" "IPR000795 (8.4%) IPR031157 (8.4%) IPR050055 (8.4%)" "Translational (tr)-type GTP-binding domain (8.4%) Tr-type G domain, conserved site (8.4%) Elongation factor Tu GTPase (8.4%)" KNFDEDELELLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0003677 (100%) DNA binding (100%) "IPR001647 (33.3%) IPR009057 (33.3%) IPR050624 (33.3%)" "DNA-binding HTH domain, TetR-type (33.3%) Homedomain-like superfamily (33.3%) HTH-type Transcriptional Regulator (33.3%)" FTTALDECEFER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR019734 (25.6%) IPR025738 (25.6%) IPR013105 (24.8%)" "Tetratricopeptide repeat (25.6%) Aerotolerance-related protein BatD (25.6%) Tetratricopeptide repeat 2 (24.8%)" LTFALLDNEETQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.8%) "GO:0016853 (33.8%) GO:0030246 (32.3%)" carbohydrate metabolic process (33.8%) "isomerase activity (33.8%) carbohydrate binding (32.3%)" "IPR008183 (25.6%) IPR037481 (25.6%) IPR011013 (24.4%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (25.6%) Protein LacX (25.6%) Galactose mutarotase-like domain superfamily (24.4%)" MNALLPFETWPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.3%) "GO:0004553 (34.3%) GO:0030246 (31.4%)" carbohydrate metabolic process (34.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.3%) carbohydrate binding (31.4%)" "IPR000322 (12.9%) IPR025887 (12.9%) IPR033403 (12.9%)" "Glycoside hydrolase family 31, TIM barrel domain (12.9%) Glycoside hydrolase family 31, N-terminal domain (12.9%) Domain of unknown function DUF5110 (12.9%)" TTELLGNAEGAEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR051200 (47.4%) IPR015943 (42.1%) IPR011044 (5.3%)" "Multi-functional host-pathogen interaction and enzymatic activity protein (47.4%) WD40/YVTN repeat-like-containing domain superfamily (42.1%) Quinoprotein amine dehydrogenase, beta chain-like (5.3%)" VMNPLSADLGVMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (7.9%) IPR002547 (7.8%) IPR004532 (7.8%)" "Phenylalanyl tRNA synthetase beta chain, core domain (7.9%) tRNA-binding domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.8%)" FLFVGEQEQYDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (34.2%) IPR042099 (33.2%) IPR020845 (32.7%)" "AMP-dependent synthetase/ligase domain (34.2%) ANL, N-terminal domain (33.2%) AMP-binding, conserved site (32.7%)" TMLDFVASTGQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.8%) IPR003385 (20.8%) IPR013783 (19.4%)" "Carbohydrate binding module family 20 (20.8%) Glycoside hydrolase, family 77 (20.8%) Immunoglobulin-like fold (19.4%)" GTVPHEVETSFGGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006412 (16.7%) GO:0042254 (11.1%)" "GO:0005737 (16.7%) GO:0015935 (11.1%) GO:0005840 (5.6%)" "GO:0003735 (16.7%) GO:0019843 (11.1%) GO:0003723 (5.6%)" "translation (16.7%) ribosome biogenesis (11.1%)" "cytoplasm (16.7%) small ribosomal subunit (11.1%) ribosome (5.6%)" "structural constituent of ribosome (16.7%) rRNA binding (11.1%) RNA binding (5.6%)" "IPR000851 (15.4%) IPR005324 (15.4%) IPR013810 (15.4%)" "Small ribosomal subunit protein uS5 (15.4%) Small ribosomal subunit protein uS5, C-terminal (15.4%) Small ribosomal subunit protein uS5, N-terminal (15.4%)" ASETGGTLEKPYTVAQALEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) NQQMDDHYFGTLPER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.3%) IPR008147 (14.3%) IPR022147 (14.3%)" "Glutamine synthetase, catalytic domain (14.3%) Glutamine synthetase, N-terminal domain (14.3%) Glutamine synthetase type III N-terminal (14.3%)" NYHALLVTGLASPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.130 (100%) tetraacyldisaccharide 4'-kinase (100%) "GO:0009244 (20%) GO:0009245 (20%)" GO:0005886 (20%) "GO:0005524 (20%) GO:0009029 (20%)" "lipopolysaccharide core region biosynthetic process (20%) lipid A biosynthetic process (20%)" plasma membrane (20%) "ATP binding (20%) lipid-A 4'-kinase activity (20%)" "IPR003758 (50%) IPR027417 (50%)" "Tetraacyldisaccharide 4'-kinase (50%) P-loop containing nucleoside triphosphate hydrolase (50%)" QLLMVAGFDR root "6.1.1.23 (67.1%) 6.1.1.12 (32.8%) 6.1.1.- (0%)" "aspartate--tRNA(Asn) ligase (67.1%) aspartate--tRNA ligase (32.8%) Ligases forming aminoacyl-tRNA and related compounds (0%)" GO:0006422 (17.8%) "GO:0005737 (17.6%) GO:0005739 (0.1%) GO:0005829 (0%)" "GO:0004815 (17.8%) GO:0005524 (17.8%) GO:0003676 (17.7%)" aspartyl-tRNA aminoacylation (17.8%) "cytoplasm (17.6%) mitochondrion (0.1%) cytosol (0%)" "aspartate-tRNA ligase activity (17.8%) ATP binding (17.8%) nucleic acid binding (17.7%)" "IPR004364 (9.2%) IPR045864 (9.2%) IPR002312 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (9.2%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.2%)" LLPVTPPELRPLVPLDGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) GO:0000428 (16.9%) "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (16%)" DNA-templated transcription (16.9%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (16%)" "IPR006592 (9.3%) IPR007080 (9.3%) IPR045867 (9.3%)" "RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 1 (9.3%) DNA-directed RNA polymerase, subunit beta-prime (9.3%)" HLTVNYMMAK root 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) "GO:0006437 (16.8%) GO:0006083 (0%) GO:0043039 (0%)" GO:0005829 (16.8%) "GO:0004831 (16.8%) GO:0005524 (16.8%) GO:0003723 (16.8%)" "tyrosyl-tRNA aminoacylation (16.8%) acetate metabolic process (0%) tRNA aminoacylation (0%)" cytosol (16.8%) "tyrosine-tRNA ligase activity (16.8%) ATP binding (16.8%) RNA binding (16.8%)" "IPR002305 (12.8%) IPR002307 (12.8%) IPR024088 (12.8%)" "Aminoacyl-tRNA synthetase, class Ic (12.8%) Tyrosine-tRNA ligase (12.8%) Tyrosine-tRNA ligase, bacterial-type (12.8%)" QEGLVGGNYGQSNYER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.1%) IPR023996 (13.1%) IPR023997 (13.1%)" "TonB-dependent receptor, plug domain (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.1%)" LGVAGLLTDGETGQTAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (0.9%) "GO:0004743 (20.4%) GO:0016301 (20.4%) GO:0000287 (19.4%)" response to stress (0.9%) "pyruvate kinase activity (20.4%) kinase activity (20.4%) magnesium ion binding (19.4%)" "IPR015795 (11.8%) IPR001697 (11.3%) IPR015793 (11.3%)" "Pyruvate kinase, C-terminal (11.8%) Pyruvate kinase (11.3%) Pyruvate kinase, barrel (11.3%)" QHELEEAQASVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" KGLDLNLTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.2%) IPR022615 (20.2%) IPR056147 (20.2%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.2%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.2%) NqrA, N-terminal barrel-sandwich hybrid domain (20.2%)" HLSVLPLGGGNVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0043093 (30.8%) GO:0051301 (2.6%)" "GO:0009898 (33.3%) GO:0032153 (33.3%)" "FtsZ-dependent cytokinesis (30.8%) cell division (2.6%)" "cytoplasmic side of plasma membrane (33.3%) cell division site (33.3%)" "IPR043129 (26%) IPR050696 (26%) IPR003494 (24%)" "ATPase, nucleotide binding domain (26%) Bacterial cell division protein FtsA/MreB (26%) SHS2 domain inserted in FtsA (24%)" NQVVPSDLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (49.3%) "GO:0016787 (49.3%) GO:0016798 (1.4%)" carbohydrate metabolic process (49.3%) "hydrolase activity (49.3%) hydrolase activity, acting on glycosyl bonds (1.4%)" "IPR012878 (17.2%) IPR049046 (17.2%) IPR049049 (17.2%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17.2%)" YLDYKDPEFLK root GO:0006412 (25%) "GO:0022627 (24.9%) GO:0005840 (0.2%) GO:1990904 (0.1%)" "GO:0003735 (25%) GO:0070181 (24.9%) GO:0019843 (0.1%)" translation (25%) "cytosolic small ribosomal subunit (24.9%) ribosome (0.2%) ribonucleoprotein complex (0.1%)" "structural constituent of ribosome (25%) small ribosomal subunit rRNA binding (24.9%) rRNA binding (0.1%)" "IPR001648 (33.2%) IPR018275 (33.2%) IPR036870 (33.2%)" "Small ribosomal subunit protein bS18 (33.2%) Small ribosomal subunit protein bS18, conserved site (33.2%) Small ribosomal subunit protein bS18 superfamily (33.2%)" MNNAWVNQSASVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" SFDFLLK root "7.6.2.2 (45.2%) 6.1.1.4 (16.7%) 3.2.1.55 (4%)" "ABC-type xenobiotic transporter (45.2%) leucine--tRNA ligase (16.7%) non-reducing end alpha-L-arabinofuranosidase (4%)" "GO:0006412 (12.3%) GO:0006397 (1.1%) GO:0008033 (0.9%)" "GO:0022625 (12.3%) GO:0016020 (4.6%) GO:0005886 (1.5%)" "GO:0003735 (12.4%) GO:0070180 (12.2%) GO:0005524 (4.4%)" "translation (12.3%) mRNA processing (1.1%) tRNA processing (0.9%)" "cytosolic large ribosomal subunit (12.3%) membrane (4.6%) plasma membrane (1.5%)" "structural constituent of ribosome (12.4%) large ribosomal subunit rRNA binding (12.2%) ATP binding (4.4%)" "IPR000911 (7.6%) IPR020783 (7.6%) IPR020784 (7.6%)" "Ribosomal protein uL11 (7.6%) Large ribosomal subunit protein uL11, C-terminal (7.6%) Large ribosomal subunit protein uL11, N-terminal (7.6%)" GVMYDTSSLER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (25.3%) IPR017918 (25.3%) IPR011322 (24.7%)" "Nitrogen regulatory protein PII (25.3%) Nitrogen regulatory protein PII, conserved site (25.3%) Nitrogen regulatory PII-like, alpha/beta (24.7%)" KLELVCNFQPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.9 (100%) glucose-6-phosphate isomerase (100%) "GO:0006094 (14.4%) GO:0006096 (14.4%) GO:0051156 (14.4%)" GO:0005829 (14.4%) "GO:0004347 (14.4%) GO:0048029 (14.4%) GO:0097367 (13.9%)" "gluconeogenesis (14.4%) glycolytic process (14.4%) glucose 6-phosphate metabolic process (14.4%)" cytosol (14.4%) "glucose-6-phosphate isomerase activity (14.4%) monosaccharide binding (14.4%) carbohydrate derivative binding (13.9%)" "IPR001672 (20.5%) IPR035482 (20.5%) IPR018189 (19.9%)" "Phosphoglucose isomerase (PGI) (20.5%) Phosphoglucose isomerase, SIS domain 2 (20.5%) Phosphoglucose isomerase, conserved site (19.9%)" AWEYQLLHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0009251 (46.2%) GO:0031222 (1.9%) GO:0045493 (1.9%)" "GO:0008422 (46.2%) GO:0009044 (1.9%) GO:0046556 (1.9%)" "glucan catabolic process (46.2%) arabinan catabolic process (1.9%) xylan catabolic process (1.9%)" "beta-glucosidase activity (46.2%) xylan 1,4-beta-xylosidase activity (1.9%) alpha-L-arabinofuranosidase activity (1.9%)" "IPR002772 (13.4%) IPR001764 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase family 3 C-terminal domain (13.4%) Glycoside hydrolase, family 3, N-terminal (12.8%) Fibronectin type III-like domain (12.8%)" TEGAESALNMAGLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) TEEEALEMLK root 6.-.-.- (100%) Ligases (100%) "GO:0015977 (15.4%) GO:0009063 (7.4%) GO:0016052 (7.4%)" GO:0009317 (15.4%) "GO:0004658 (16.8%) GO:0003989 (15.4%) GO:0000287 (7.4%)" "carbon fixation (15.4%) amino acid catabolic process (7.4%) carbohydrate catabolic process (7.4%)" acetyl-CoA carboxylase complex (15.4%) "propionyl-CoA carboxylase activity (16.8%) acetyl-CoA carboxylase activity (15.4%) magnesium ion binding (7.4%)" "IPR011762 (12.6%) IPR011763 (12.6%) IPR034733 (12.6%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (12.6%) Acetyl-coenzyme A carboxyltransferase, C-terminal (12.6%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (12.6%)" AADFAAEDNDADQLLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (46.7%) "GO:0052689 (46.7%) GO:0004557 (6.7%)" cell outer membrane (46.7%) "carboxylic ester hydrolase activity (46.7%) alpha-galactosidase activity (6.7%)" "IPR011050 (25%) IPR012334 (25%) IPR032812 (25%)" "Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%) SbsA, Ig-like domain (25%)" YLDYQVNLGNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003959 (26%) IPR051396 (26%) IPR027417 (25.7%)" "ATPase, AAA-type, core (26%) Bacterial Antiviral Defense Nuclease (26%) P-loop containing nucleoside triphosphate hydrolase (25.7%)" WLYQTPEQLLLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.4%) GO:0006164 (0.7%)" GO:0005737 (20.1%) "GO:0004642 (20.1%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.4%) purine nucleotide biosynthetic process (0.7%)" cytoplasm (20.1%) "phosphoribosylformylglycinamidine synthase activity (20.1%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR010918 (11.2%) IPR036921 (11.2%) IPR036676 (11.2%)" "PurM-like, C-terminal domain (11.2%) PurM-like, N-terminal domain superfamily (11.2%) PurM-like, C-terminal domain superfamily (11.2%)" GDLALYNAEQEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (25.1%) IPR011322 (25.1%) IPR015867 (25.1%)" "Nitrogen regulatory protein PII (25.1%) Nitrogen regulatory PII-like, alpha/beta (25.1%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25.1%)" AGNFVLLR root "1.4.1.13 (50%) 2.6.1.9 (25%) 6.1.1.19 (25%)" "glutamate synthase (NADPH) (50%) histidinol-phosphate transaminase (25%) arginine--tRNA ligase (25%)" "GO:0006221 (1.8%) GO:0016226 (1.8%) GO:0000105 (0.9%)" "GO:0097361 (1.8%) GO:0000123 (0.9%)" "GO:0016491 (41.3%) GO:0051536 (38.5%) GO:0004355 (1.8%)" "pyrimidine nucleotide biosynthetic process (1.8%) iron-sulfur cluster assembly (1.8%) L-histidine biosynthetic process (0.9%)" "cytosolic [4Fe-4S] assembly targeting complex (1.8%) histone acetyltransferase complex (0.9%)" "oxidoreductase activity (41.3%) iron-sulfur cluster binding (38.5%) glutamate synthase (NADPH) activity (1.8%)" "IPR017938 (11%) IPR017927 (10.8%) IPR019480 (10.3%)" "Riboflavin synthase-like beta-barrel (11%) FAD-binding domain, ferredoxin reductase-type (10.8%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (10.3%)" LADKLNQLSYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" YPLDSLEDGLDENDWDNWVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.7%) GO:0009986 (16.7%)" "GO:0000287 (16.7%) GO:0004634 (16.7%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.7%) cell surface (16.7%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%)" "IPR000941 (16.7%) IPR020809 (16.7%) IPR020810 (16.7%)" "Enolase (16.7%) Enolase, conserved site (16.7%) Enolase, C-terminal TIM barrel domain (16.7%)" TEYLSCPGCGR Pseudomonadati Bacteria Pseudomonadati "1.17.7.3 (95.1%) 1.17.7.1 (4.9%)" "(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin) (95.1%) (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin) (4.9%)" "GO:0016114 (17.5%) GO:0019288 (17.5%)" "GO:0046429 (17.5%) GO:0051539 (17.5%) GO:0005506 (16.9%)" "terpenoid biosynthetic process (17.5%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (17.5%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin) (17.5%) 4 iron, 4 sulfur cluster binding (17.5%) iron ion binding (16.9%)" "IPR004588 (25.5%) IPR045854 (25.1%) IPR011005 (24.8%)" "4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type (25.5%) Nitrite and sulphite reductase 4Fe-4S domain-like superfamily (25.1%) Dihydropteroate synthase-like superfamily (24.8%)" HLWWENDLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025631 (100%) Putative porin-10 (100%) EVNELATVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20%) IPR008932 (20%) IPR013823 (20%)" "Large ribosomal subunit protein bL12 (20%) Large ribosomal subunit protein bL12, oligomerization (20%) Large ribosomal subunit protein bL12, C-terminal (20%)" DYDVFVGK Bacteria Bacteria 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006412 (24.6%) GO:0006935 (0.1%) GO:0007165 (0.1%)" "GO:0022627 (23.9%) GO:0005840 (1%) GO:1990904 (0.7%)" "GO:0003729 (24.6%) GO:0003735 (24.6%) GO:0004654 (0.1%)" "translation (24.6%) chemotaxis (0.1%) signal transduction (0.1%)" "cytosolic small ribosomal subunit (23.9%) ribosome (1%) ribonucleoprotein complex (0.7%)" "mRNA binding (24.6%) structural constituent of ribosome (24.6%) polyribonucleotide nucleotidyltransferase activity (0.1%)" "IPR003029 (24.4%) IPR050437 (24.4%) IPR012340 (24.3%)" "S1 domain (24.4%) Small ribosomal subunit protein bS1-like (24.4%) Nucleic acid-binding, OB-fold (24.3%)" NGLEENTLDNPTNLYPVENYVTTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" DVPAALTQELLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016491 (33.3%) GO:0046872 (33.3%) GO:0051287 (33.3%)" "oxidoreductase activity (33.3%) metal ion binding (33.3%) NAD binding (33.3%)" IPR005255 (100%) PdxA family (100%) SVDPSLDREAQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0015031 (16.9%) GO:0055085 (16.9%) GO:0015891 (16.1%)" "GO:0098797 (16.9%) GO:0030288 (16.1%)" GO:0031992 (16.9%) "protein transport (16.9%) transmembrane transport (16.9%) siderophore transport (16.1%)" "plasma membrane protein complex (16.9%) outer membrane-bounded periplasmic space (16.1%)" energy transducer activity (16.9%) "IPR006260 (25.3%) IPR037682 (25.3%) IPR051045 (25.3%)" "TonB/TolA, C-terminal (25.3%) TonB, C-terminal (25.3%) TonB-dependent transporter energy transducer (25.3%)" GTLAEVLAHFEETEPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.1.198 (100%) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (100%) GO:0005737 (50%) GO:0070677 (50%) cytoplasm (50%) rRNA (cytosine-2'-O-)-methyltransferase activity (50%) "IPR000878 (18.3%) IPR008189 (18.3%) IPR014776 (15.9%)" "Tetrapyrrole methylase (18.3%) rRNA small subunit methyltransferase I (18.3%) Tetrapyrrole methylase, subdomain 2 (15.9%)" LLLADEPTGNLDPETASNLVSLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (20.3%) IPR003593 (20.3%) IPR015854 (20.3%)" "ABC transporter-like, ATP-binding domain (20.3%) AAA+ ATPase domain (20.3%) ABC transporter, lipoprotein release, LolD-like (20.3%)" MEVQNSYNMAMTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" VDDNDLMETAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.7%) GO:0043335 (15.7%) GO:0051083 (15.7%)" GO:0005737 (5.6%) "GO:0003755 (15.7%) GO:0043022 (15.7%) GO:0044183 (15.7%)" "protein transport (15.7%) protein unfolding (15.7%) 'de novo' cotranslational protein folding (15.7%)" cytoplasm (5.6%) "peptidyl-prolyl cis-trans isomerase activity (15.7%) ribosome binding (15.7%) protein folding chaperone (15.7%)" "IPR005215 (18.7%) IPR008881 (18.7%) IPR027304 (18.7%)" "Trigger factor (18.7%) Trigger factor, ribosome-binding, bacterial (18.7%) Trigger factor/SurA domain superfamily (18.7%)" DVYTSLANYEAVLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" LGDPELLK root "1.4.1.23 (40.9%) 2.7.13.3 (11.4%) 6.1.1.4 (11.4%)" "valine dehydrogenase (NAD(+)) (40.9%) histidine kinase (11.4%) leucine--tRNA ligase (11.4%)" "GO:0006574 (2.2%) GO:0044057 (1.2%) GO:0006429 (0.8%)" "GO:0016020 (6.6%) GO:0005737 (6.5%) GO:0005829 (1.7%)" "GO:0050660 (8.8%) GO:0016614 (8.7%) GO:0000166 (2.7%)" "L-valine catabolic process (2.2%) regulation of system process (1.2%) leucyl-tRNA aminoacylation (0.8%)" "membrane (6.6%) cytoplasm (6.5%) cytosol (1.7%)" "flavin adenine dinucleotide binding (8.8%) oxidoreductase activity, acting on CH-OH group of donors (8.7%) nucleotide binding (2.7%)" "IPR000172 (5.3%) IPR012132 (5.2%) IPR036188 (5.1%)" "Glucose-methanol-choline oxidoreductase, N-terminal (5.3%) Glucose-methanol-choline oxidoreductase (5.2%) FAD/NAD(P)-binding domain superfamily (5.1%)" CALNAPVYTLDDTTPTSYSAFVGTDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VCNDFLSK root "GO:0009279 (48.1%) GO:0005634 (11.1%) GO:0005829 (11.1%)" "GO:0005524 (11.1%) GO:0140662 (11.1%)" "cell outer membrane (48.1%) nucleus (11.1%) cytosol (11.1%)" "ATP binding (11.1%) ATP-dependent protein folding chaperone (11.1%)" "IPR011990 (23.3%) IPR012944 (21.7%) IPR033985 (21.7%)" "Tetratricopeptide-like helical domain superfamily (23.3%) RagB/SusD domain (21.7%) SusD-like, N-terminal (21.7%)" NNEVVYVPLSEALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" GO:0005945 (9.1%) "GO:0003872 (9.1%) GO:0005524 (9.1%) GO:0016208 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" 6-phosphofructokinase complex (9.1%) "6-phosphofructokinase activity (9.1%) ATP binding (9.1%) AMP binding (9.1%)" "IPR000023 (17%) IPR012828 (16.7%) IPR015912 (16.7%)" "Phosphofructokinase domain (17%) ATP-dependent 6-phosphofructokinase, prokaryotic (16.7%) Phosphofructokinase, conserved site (16.7%)" LSLGKPLPWQTFDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) YAVEPYRVEQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.3%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.3%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011263 (16.9%) IPR036603 (16.9%) IPR011260 (16.5%)" "DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.9%) RNA polymerase, RBP11-like subunit (16.9%) RNA polymerase, alpha subunit, C-terminal (16.5%)" LNASVTYSDYTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" YWGFVPEDHLVGK Pseudomonadati Bacteria Pseudomonadati 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (24%) IPR019533 (24%) IPR019758 (24%)" "Peptidase S26A, signal peptidase I (24%) Peptidase S26 (24%) Peptidase S26A, signal peptidase I, conserved site (24%)" ALTDCVVTSGNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.72 (100%) quinolinate synthase (100%) GO:0034628 (20%) GO:0005829 (20%) "GO:0008987 (20%) GO:0046872 (20%) GO:0051539 (20%)" 'de novo' NAD+ biosynthetic process from L-aspartate (20%) cytosol (20%) "quinolinate synthetase A activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR003473 (51.7%) IPR036094 (48.3%)" "Quinolinate synthetase A (51.7%) Quinolinate synthetase A superfamily (48.3%)" TTVSLSAENLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" SVGELMSLGR root "6.3.5.5 (76.9%) 6.3.4.16 (23.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (76.9%) carbamoyl-phosphate synthase (ammonia) (23.1%)" "GO:0006541 (13.9%) GO:0006526 (11.4%) GO:0006221 (11%)" "GO:0005737 (13.5%) GO:0005951 (0.3%) GO:0005829 (0.1%)" "GO:0004088 (13.9%) GO:0005524 (13.9%) GO:0046872 (13.8%)" "glutamine metabolic process (13.9%) L-arginine biosynthetic process (11.4%) pyrimidine nucleotide biosynthetic process (11%)" "cytoplasm (13.5%) carbamoyl-phosphate synthase complex (0.3%) cytosol (0.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.9%) ATP binding (13.9%) metal ion binding (13.8%)" "IPR005480 (10%) IPR005479 (9.9%) IPR011761 (9.9%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10%) Carbamoyl phosphate synthase, ATP-binding domain (9.9%) ATP-grasp fold (9.9%)" VGNLMNPDDYFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) "IPR001296 (34.1%) IPR028098 (34.1%) IPR050194 (31.7%)" "Glycosyl transferase, family 1 (34.1%) Glycosyltransferase subfamily 4-like, N-terminal domain (34.1%) Glycosyltransferase group 1 (31.7%)" RPSPYDAPHNPLNLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TTLTAALSK root "3.6.5.3 (99.9%) 4.1.3.27 (0.1%)" "protein-synthesizing GTPase (99.9%) anthranilate synthase (0.1%)" "GO:0070125 (0.1%) GO:0032790 (0%) GO:0006508 (0%)" "GO:0005829 (19.1%) GO:0032045 (1.8%) GO:0005739 (0.1%)" "GO:0003746 (19.3%) GO:0003924 (19.3%) GO:0005525 (19.3%)" "mitochondrial translational elongation (0.1%) ribosome disassembly (0%) proteolysis (0%)" "cytosol (19.1%) guanyl-nucleotide exchange factor complex (1.8%) mitochondrion (0.1%)" "translation elongation factor activity (19.3%) GTPase activity (19.3%) GTP binding (19.3%)" "IPR000795 (8.4%) IPR027417 (8.4%) IPR050055 (8.3%)" "Translational (tr)-type GTP-binding domain (8.4%) P-loop containing nucleoside triphosphate hydrolase (8.4%) Elongation factor Tu GTPase (8.3%)" NTVLYNMVTHGDLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.5%) GO:0016020 (0.8%)" "GO:0008658 (11.3%) GO:0008955 (11.3%) GO:0004180 (10.5%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.5%) membrane (0.8%)" "penicillin binding (11.3%) peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.5%)" "IPR001264 (17.3%) IPR001460 (17.3%) IPR050396 (17.3%)" "Glycosyl transferase, family 51 (17.3%) Penicillin-binding protein, transpeptidase (17.3%) Glycosyltransferase 51/Transpeptidase (17.3%)" LLHLNLQPGSEEAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VNAALENEEVLQGYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (23.9%) IPR012340 (23.9%) IPR035104 (23.9%)" "S1 domain (23.9%) Nucleic acid-binding, OB-fold (23.9%) Ribosomal protein S1-like (23.9%)" CLLDPELGALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (16.7%) GO:0006085 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0005524 (16.7%) GO:0008776 (16.7%)" "acetate metabolic process (16.7%) acetyl-CoA biosynthetic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) ATP binding (16.7%) acetate kinase activity (16.7%)" "IPR000890 (25.2%) IPR004372 (25.2%) IPR023865 (25.2%)" "Aliphatic acid kinase, short-chain (25.2%) Acetate/propionate kinase (25.2%) Aliphatic acid kinase, short-chain, conserved site (25.2%)" TPEGSVVEELVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) "GO:0004180 (33.3%) GO:0030246 (16.7%)" cell outer membrane (50%) "carboxypeptidase activity (33.3%) carbohydrate binding (16.7%)" "IPR041700 (74%) IPR008969 (20.5%) IPR036942 (4.1%)" "Outer membrane protein beta-barrel domain 3 (74%) Carboxypeptidase-like, regulatory domain superfamily (20.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (4.1%)" DFLLMGELLAYDALHR Pseudomonadati Bacteria Pseudomonadati 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (19.8%) GO:0005886 (19.8%) "GO:0009055 (19.8%) GO:0050660 (19.8%) GO:0000104 (16.7%)" anaerobic respiration (19.8%) plasma membrane (19.8%) "electron transfer activity (19.8%) flavin adenine dinucleotide binding (19.8%) succinate dehydrogenase activity (16.7%)" "IPR015939 (15.3%) IPR030664 (14.7%) IPR037099 (14.7%)" "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (15.3%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.7%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily (14.7%)" ASFNGADPLVQVDGVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" YAVEPYR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (13.1%) GO:0035721 (3%) GO:0060271 (1.8%)" "GO:0005737 (13.6%) GO:0000428 (13.1%) GO:0005930 (3%)" "GO:0003677 (13.1%) GO:0003899 (13.1%) GO:0046983 (13.1%)" "DNA-templated transcription (13.1%) intraciliary retrograde transport (3%) cilium assembly (1.8%)" "cytoplasm (13.6%) DNA-directed RNA polymerase complex (13.1%) axoneme (3%)" "DNA binding (13.1%) DNA-directed RNA polymerase activity (13.1%) protein dimerization activity (13.1%)" "IPR011263 (11.5%) IPR036603 (11.5%) IPR011260 (11.3%)" "DNA-directed RNA polymerase, RpoA/D/Rpb3-type (11.5%) RNA polymerase, RBP11-like subunit (11.5%) RNA polymerase, alpha subunit, C-terminal (11.3%)" FKVEDLDEFYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.4.16 (100%) thiamine-phosphate kinase (100%) "GO:0009228 (20%) GO:0009229 (20%)" "GO:0000287 (20%) GO:0005524 (20%) GO:0009030 (20%)" "thiamine biosynthetic process (20%) thiamine diphosphate biosynthetic process (20%)" "magnesium ion binding (20%) ATP binding (20%) thiamine-phosphate kinase activity (20%)" "IPR006283 (24%) IPR016188 (24%) IPR036676 (22%)" "Thiamine-monophosphate kinase-like (24%) PurM-like, N-terminal domain (24%) PurM-like, C-terminal domain superfamily (22%)" YMAAGVYPYFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030170 (51.3%) GO:0008483 (46.2%) GO:0016740 (2.6%)" "pyridoxal phosphate binding (51.3%) transaminase activity (46.2%) transferase activity (2.6%)" "IPR004839 (17.2%) IPR050087 (17.2%) IPR001917 (16.4%)" "Aminotransferase, class I/classII, large domain (17.2%) 8-amino-7-oxononanoate synthase class-II (17.2%) Aminotransferase, class-II, pyridoxal-phosphate binding site (16.4%)" TKGEPGTGDVVQAVTHMR Bacteria Bacteria 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (24.3%) GO:0016843 (0.7%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (24.3%) amine-lyase activity (0.7%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" LQFGPELQYYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.7%) IPR023996 (13.7%) IPR023997 (13.7%)" "TonB-dependent receptor, plug domain (13.7%) TonB-dependent outer membrane protein, SusC/RagA (13.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.7%)" KEDLSAVAFTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.3.1.234 (100%) N(6)-L-threonylcarbamoyladenine synthase (100%) "GO:0002949 (23.9%) GO:0006508 (2.8%)" GO:0005737 (22.5%) "GO:0005506 (22.5%) GO:0061711 (12.7%) GO:0016747 (11.3%)" "tRNA threonylcarbamoyladenosine modification (23.9%) proteolysis (2.8%)" cytoplasm (22.5%) "iron ion binding (22.5%) tRNA N(6)-L-threonylcarbamoyladenine synthase activity (12.7%) acyltransferase activity, transferring groups other than amino-acyl groups (11.3%)" "IPR000905 (20%) IPR017860 (20%) IPR017861 (20%)" "Gcp-like domain (20%) Peptidase M22, conserved site (20%) Kae1/TsaD family (20%)" AFSFSPQVLVEK Pseudomonadati Bacteria Pseudomonadati "6.3.5.5 (95.6%) 6.3.4.16 (4.1%) 6.3.4.6 (0.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (95.6%) carbamoyl-phosphate synthase (ammonia) (4.1%) urea carboxylase (0.3%)" "GO:0006541 (14.2%) GO:0006221 (10.9%) GO:0006526 (10.8%)" GO:0005737 (14.2%) "GO:0004088 (14.2%) GO:0005524 (14.2%) GO:0046872 (14.1%)" "glutamine metabolic process (14.2%) pyrimidine nucleotide biosynthetic process (10.9%) L-arginine biosynthetic process (10.8%)" cytoplasm (14.2%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.2%) ATP binding (14.2%) metal ion binding (14.1%)" "IPR005479 (10.2%) IPR011761 (10.2%) IPR005483 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.2%) ATP-grasp fold (10.2%) Carbamoyl phosphate synthase, CPSase domain (10.1%)" VTTTYLCPQSDPLLGFAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030246 (48.1%) GO:0016798 (46.3%) GO:0016787 (5.6%)" "carbohydrate binding (48.1%) hydrolase activity, acting on glycosyl bonds (46.3%) hydrolase activity (5.6%)" "IPR019563 (13.1%) IPR029486 (13.1%) IPR052720 (13.1%)" "Glycosyl-hydrolase 97, catalytic domain (13.1%) Glycosyl-hydrolase 97, N-terminal domain (13.1%) Glycosyl Hydrolase Family 97 (13.1%)" ATLSYDGYYGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LALLYYADGEK root "GO:0002181 (19.8%) GO:0032543 (0.1%)" "GO:0015934 (19.8%) GO:0005762 (0.1%) GO:0009507 (0.1%)" "GO:0003735 (19.9%) GO:0016740 (19.9%) GO:0019843 (19.1%)" "cytoplasmic translation (19.8%) mitochondrial translation (0.1%)" "large ribosomal subunit (19.8%) mitochondrial large ribosomal subunit (0.1%) chloroplast (0.1%)" "structural constituent of ribosome (19.9%) transferase activity (19.9%) rRNA binding (19.1%)" "IPR002171 (11.2%) IPR005880 (11.2%) IPR008991 (11.2%)" "Large ribosomal subunit protein uL2 (11.2%) Large ribosomal subunit protein uL2, bacteria/organella (11.2%) Translation protein SH3-like domain superfamily (11.2%)" LYTLGVPYDNDDVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) LTVVGDPTSLDHVEQFLGNAVK Bacteria Bacteria GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.6%) IPR006512 (25.6%) IPR050144 (25.6%)" "Regulator of K+ conductance, C-terminal (25.6%) YidE/YbjL duplication (25.6%) AAE Transporter (25.6%)" KVLFVLPESNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" YADRDEDFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DNLVFHCLLFPTMLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002547 (8.4%) IPR004495 (8.4%) IPR014758 (8.4%)" "tRNA-binding domain (8.4%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.4%) Methionyl-tRNA synthetase (8.4%)" MNATAPALNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (34.6%) IPR031107 (34.6%) IPR008978 (30.8%)" "Alpha crystallin/Hsp20 domain (34.6%) Small heat shock protein (34.6%) HSP20-like chaperone (30.8%)" LQNEMTYPGQVK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (20%) GO:0005886 (20%) "GO:0003723 (20%) GO:0004521 (20%) GO:0016787 (20%)" mRNA catabolic process (20%) plasma membrane (20%) "RNA binding (20%) RNA endonuclease activity (20%) hydrolase activity (20%)" "IPR003607 (12.5%) IPR004087 (12.5%) IPR004088 (12.5%)" "HD/PDEase domain (12.5%) K Homology domain (12.5%) K Homology domain, type 1 (12.5%)" SLVELHYGTLTAANNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (0.7%) "GO:0000155 (25.2%) GO:0005524 (25.2%) GO:0003700 (24.5%)" membrane (0.7%) "phosphorelay sensor kinase activity (25.2%) ATP binding (25.2%) DNA-binding transcription factor activity (24.5%)" "IPR001789 (7.4%) IPR003594 (7.4%) IPR005467 (7.4%)" "Signal transduction response regulator, receiver domain (7.4%) Histidine kinase/HSP90-like ATPase domain (7.4%) Histidine kinase domain (7.4%)" TVLLMELLNNLAK root "7.1.2.2 (100%) 3.6.3.14 (0%)" "H(+)-transporting two-sector ATPase (100%) Transferred entry: 7.1.2.2 (0%)" "GO:0042776 (16.5%) GO:0006754 (0%) GO:1902600 (0%)" "GO:0045259 (16.6%) GO:0005739 (16.5%) GO:0009535 (15.8%)" "GO:0005524 (16.7%) GO:0046933 (16.6%) GO:0016887 (0.2%)" "proton motive force-driven mitochondrial ATP synthesis (16.5%) ATP biosynthetic process (0%) proton transmembrane transport (0%)" "proton-transporting ATP synthase complex (16.6%) mitochondrion (16.5%) chloroplast thylakoid membrane (15.8%)" "ATP binding (16.7%) proton-transporting ATP synthase activity, rotational mechanism (16.6%) ATP hydrolysis activity (0.2%)" "IPR050053 (10.2%) IPR000194 (10.2%) IPR027417 (10.2%)" "ATPase alpha/beta chains (10.2%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.2%) P-loop containing nucleoside triphosphate hydrolase (10.2%)" VSMTPEQLYGNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (16.7%) GO:0006417 (16.7%)" GO:0015934 (16.7%) "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" "translation (16.7%) regulation of translation (16.7%)" large ribosomal subunit (16.7%) "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002143 (16.7%) IPR005878 (16.7%) IPR016095 (16.7%)" "Large ribosomal subunit protein uL1 (16.7%) Large ribosomal subunit protein uL1, bacteria (16.7%) Large ribosomal subunit protein uL1, 3-layer alpha/beta-sandwich domain (16.7%)" EMQFFGAR root 2.3.1.54 (100%) formate C-acetyltransferase (100%) "GO:0006006 (32.4%) GO:0005975 (0%)" "GO:0005829 (33.5%) GO:0016020 (0%)" "GO:0008861 (33.5%) GO:0016829 (0.5%)" "glucose metabolic process (32.4%) carbohydrate metabolic process (0%)" "cytosol (33.5%) membrane (0%)" "formate C-acetyltransferase activity (33.5%) lyase activity (0.5%)" "IPR004184 (21.4%) IPR050244 (21.4%) IPR001150 (21.1%)" "Pyruvate formate lyase domain (21.4%) Autonomous Glycyl Radical Cofactor (21.4%) Glycine radical domain (21.1%)" DNEPELFDKLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR000577 (20%) IPR018484 (20%) IPR018485 (20%)" "Carbohydrate kinase, FGGY (20%) Carbohydrate kinase FGGY, N-terminal (20%) Carbohydrate kinase FGGY, C-terminal (20%)" LNFLLFDKEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.7%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.7%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" NTGFELAVNAHPLANK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (14.8%) IPR039426 (14.8%) IPR008969 (14.1%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (14.8%) TonB-dependent receptor-like (14.8%) Carboxypeptidase-like, regulatory domain superfamily (14.1%)" RNEYYGLNALYETWYNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" GDLLGGVSVVDVEGLMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.3%) IPR023996 (31.4%) IPR037066 (31.4%)" "TonB-dependent receptor, plug domain (34.3%) TonB-dependent outer membrane protein, SusC/RagA (31.4%) TonB-dependent receptor, plug domain superfamily (31.4%)" EALDYLNK root "2.7.13.3 (22.7%) 2.3.1.1 (13.6%) 2.3.1.35 (13.6%)" "histidine kinase (22.7%) amino-acid N-acetyltransferase (13.6%) glutamate N-acetyltransferase (13.6%)" "GO:0006979 (6.7%) GO:0022900 (6.5%) GO:0044281 (6.2%)" "GO:0005737 (3.5%) GO:0016020 (3%) GO:0005634 (2.1%)" "GO:0005506 (7%) GO:0051539 (6.7%) GO:0030976 (6.5%)" "response to oxidative stress (6.7%) electron transport chain (6.5%) small molecule metabolic process (6.2%)" "cytoplasm (3.5%) membrane (3%) nucleus (2.1%)" "iron ion binding (7%) 4 iron, 4 sulfur cluster binding (6.7%) thiamine pyrophosphate binding (6.5%)" "IPR002880 (4%) IPR017896 (4%) IPR017900 (4%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (4%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (4%)" LLVEVGNPGDENLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) YQLQPVWR root 6.1.1.21 (100%) histidine--tRNA ligase (100%) "GO:0006427 (24.9%) GO:0006418 (0.1%) GO:0006412 (0%)" "GO:0005737 (24.9%) GO:0005829 (0%)" "GO:0004821 (25%) GO:0005524 (24.9%) GO:0016874 (0.1%)" "histidyl-tRNA aminoacylation (24.9%) tRNA aminoacylation for protein translation (0.1%) translation (0%)" "cytoplasm (24.9%) cytosol (0%)" "histidine-tRNA ligase activity (25%) ATP binding (24.9%) ligase activity (0.1%)" "IPR041715 (12.8%) IPR045864 (12.8%) IPR015807 (12.7%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (12.8%) Histidine-tRNA ligase (12.7%)" VYMVGNVLLDNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.1.3.14 (66.7%) 5.1.3.- (33.3%)" "UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) (66.7%) Acting on carbohydrates and derivatives (33.3%)" "GO:0016853 (87.1%) GO:0008761 (12.9%)" "isomerase activity (87.1%) UDP-N-acetylglucosamine 2-epimerase activity (12.9%)" "IPR003331 (50%) IPR029767 (50%)" "UDP-N-acetylglucosamine 2-epimerase domain (50%) UDP-N-acetylglucosamine 2-epimerase WecB-like (50%)" VPCLTTDLAGFGLWANSEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.11 (100%) glycogen(starch) synthase (100%) GO:0005978 (33.3%) GO:0005737 (33.3%) GO:0004373 (33.3%) glycogen biosynthetic process (33.3%) cytoplasm (33.3%) alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity (33.3%) IPR008631 (100%) Glycogen synthase (100%) YTVLTAMGNNVLFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YQSLAVGFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005829 (33.3%) "GO:0003677 (33.3%) GO:0003700 (33.3%)" cytosol (33.3%) "DNA binding (33.3%) DNA-binding transcription factor activity (33.3%)" "IPR001387 (16.7%) IPR010982 (16.7%) IPR011051 (16.7%)" "Cro/C1-type, helix-turn-helix domain (16.7%) Lambda repressor-like, DNA-binding domain superfamily (16.7%) RmlC-like cupin domain superfamily (16.7%)" YVEDGSYLR Pseudomonadati Bacteria Pseudomonadati "GO:0044718 (10.4%) GO:0006826 (1.1%)" GO:0009279 (77.6%) "GO:0015344 (10.4%) GO:0030246 (0.6%)" "siderophore transmembrane transport (10.4%) iron ion transport (1.1%)" cell outer membrane (77.6%) "siderophore uptake transmembrane transporter activity (10.4%) carbohydrate binding (0.6%)" "IPR023996 (14%) IPR039426 (14%) IPR012910 (13.9%)" "TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent receptor-like (14%) TonB-dependent receptor, plug domain (13.9%)" SHELVDNALK Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20%) GO:0019676 (20%)" "GO:0051538 (20%) GO:0046872 (19.6%) GO:0015930 (15.1%)" "glutamate biosynthetic process (20%) ammonia assimilation cycle (20%)" "3 iron, 4 sulfur cluster binding (20%) metal ion binding (19.6%) glutamate synthase activity (15.1%)" "IPR017932 (12.8%) IPR050711 (12.8%) IPR002489 (12.6%)" "Glutamine amidotransferase type 2 domain (12.8%) Electron transfer and nitrogen metabolism enzyme (12.8%) Glutamate synthase, alpha subunit, C-terminal (12.6%)" AVDYLPEEWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" GSLAGAELLTKDEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (93.3%) GO:0015344 (6.7%) cell outer membrane (93.3%) siderophore uptake transmembrane transporter activity (6.7%) "IPR036942 (93.3%) IPR039426 (6.7%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (93.3%) TonB-dependent receptor-like (6.7%)" TVLGDAFVNADGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" MVEDLSYNNAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (51.1%) IPR032466 (48.9%)" "Uronate isomerase (51.1%) Metal-dependent hydrolase (48.9%)" YLLGFDVGSSSVK Pseudomonadati Bacteria Pseudomonadati 2.7.1.17 (100%) xylulokinase (100%) GO:0005975 (49.2%) "GO:0016301 (49.2%) GO:0004856 (1.5%)" carbohydrate metabolic process (49.2%) "kinase activity (49.2%) D-xylulokinase activity (1.5%)" "IPR018484 (20.1%) IPR018485 (20.1%) IPR050406 (20.1%)" "Carbohydrate kinase FGGY, N-terminal (20.1%) Carbohydrate kinase FGGY, C-terminal (20.1%) FGGY Carbohydrate Kinase (20.1%)" YNLTSLLTVTSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006974 (55.2%) GO:0016020 (44.8%) DNA damage response (55.2%) membrane (44.8%) "IPR007497 (34.8%) IPR052022 (34.8%) IPR016907 (30.4%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (34.8%) 26 kDa periplasmic antigen-related (34.8%) Uncharacterised conserved protein UCP029033, periplasmic protein (30.4%)" ADETLLEFMQTDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NLKPTLFDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25.4%) IPR035376 (25.4%) IPR038143 (24.6%)" "NigD-like N-terminal OB domain (25.4%) NigD-like, C-terminal domain (25.4%) NigD-like, C-terminal domain superfamily (24.6%)" FTPGKNEFYPVPYNQLYYLPGLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.4%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.4%)" SLPEGVVLEPFLDR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005886 (27.7%) "GO:0042910 (27.7%) GO:0008324 (27%) GO:0015562 (17.5%)" plasma membrane (27.7%) "xenobiotic transmembrane transporter activity (27.7%) monoatomic cation transmembrane transporter activity (27%) efflux transmembrane transporter activity (17.5%)" "IPR001036 (27.9%) IPR027463 (27.4%) IPR004763 (27.2%)" "Acriflavin resistance protein (27.9%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (27.4%) Cation efflux system CusA-like (27.2%)" WWNQTDASGFGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.8%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.8%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" GVVWVALR root 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0006508 (29.4%) GO:0006629 (0.9%) GO:0071763 (0.9%)" "GO:0005637 (0.9%) GO:0005789 (0.9%) GO:0005886 (0.9%)" "GO:0016805 (29.4%) GO:0070004 (29.4%) GO:0003700 (1.8%)" "proteolysis (29.4%) lipid metabolic process (0.9%) nuclear membrane organization (0.9%)" "nuclear inner membrane (0.9%) endoplasmic reticulum membrane (0.9%) plasma membrane (0.9%)" "dipeptidase activity (29.4%) cysteine-type exopeptidase activity (29.4%) DNA-binding transcription factor activity (1.8%)" "IPR005322 (59.3%) IPR000182 (3.7%) IPR000835 (3.7%)" "Peptidase C69 (59.3%) GNAT domain (3.7%) MarR-type HTH domain (3.7%)" KALVELDGAPFK Bacteria Bacteria 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.5%) GO:0006002 (13.8%)" GO:0005829 (14.5%) "GO:0003872 (14.5%) GO:0047334 (14.3%) GO:0005524 (14.2%)" "response to glucose (14.5%) fructose 6-phosphate metabolic process (13.8%)" cytosol (14.5%) "6-phosphofructokinase activity (14.5%) diphosphate-fructose-6-phosphate 1-phosphotransferase activity (14.3%) ATP binding (14.2%)" "IPR000023 (25.1%) IPR011183 (25.1%) IPR035966 (25.1%)" "Phosphofructokinase domain (25.1%) Pyrophosphate-dependent phosphofructokinase PfpB (25.1%) Phosphofructokinase superfamily (25.1%)" LHLQLTQSQFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (10%) "GO:0009279 (20%) GO:1990281 (20%)" "GO:0015288 (20%) GO:0015562 (20%) GO:0008233 (10%)" proteolysis (10%) "cell outer membrane (20%) efflux pump complex (20%)" "porin activity (20%) efflux transmembrane transporter activity (20%) peptidase activity (10%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LYPHLGYLHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (63.9%) 1.6.5.9 (19.4%) 1.6.99.5 (13.9%)" "Transferred entry: 1.6.5.9 (63.9%) NADH:ubiquinone reductase (non-electrogenic) (19.4%) Transferred entry: 1.6.5.11 (13.9%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (19.1%) IPR001268 (19.1%) IPR022885 (19.1%)" "NADH-quinone oxidoreductase, subunit D (19.1%) NADH:ubiquinone oxidoreductase, 30kDa subunit (19.1%) NAD(P)H-quinone oxidoreductase subunit D/H (19.1%)" GGGDSYEVGLKPGLAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011250 (50%) IPR027385 (50%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (50%) Outer membrane protein, beta-barrel domain (50%)" GLLDALLSGDLDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.1%) GO:0005829 (17.1%) "GO:0004612 (17.1%) GO:0005524 (17.1%) GO:0046872 (17.1%)" gluconeogenesis (17.1%) cytosol (17.1%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.1%) ATP binding (17.1%) metal ion binding (17.1%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" LNEEEDVLSAFHQLQDLHQQYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR007139 (100%) Protein of unknown function DUF349 (100%) FSLAAALR root "2.4.1.- (27.8%) 5.6.2.4 (16.7%) 2.1.1.220 (11.1%)" "Hexosyltransferases (27.8%) DNA 3'-5' helicase (16.7%) tRNA (adenine(58)-N(1))-methyltransferase (11.1%)" "GO:0006506 (2.3%) GO:0048868 (2.3%) GO:0071555 (2.3%)" "GO:0016020 (5.5%) GO:0005886 (5.1%) GO:0005737 (4.6%)" "GO:0005524 (3.7%) GO:0003677 (2.8%) GO:0008410 (2.8%)" "GPI anchor biosynthetic process (2.3%) pollen tube development (2.3%) cell wall organization (2.3%)" "membrane (5.5%) plasma membrane (5.1%) cytoplasm (4.6%)" "ATP binding (3.7%) DNA binding (2.8%) CoA-transferase activity (2.8%)" "IPR045741 (12.2%) IPR047799 (12.2%) IPR027417 (3.5%)" "Type IX secretion system protein PorV (12.2%) Type IX secretion system, outer membrane channel protein PorV (12.2%) P-loop containing nucleoside triphosphate hydrolase (3.5%)" DEHYSTEGLHQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.5 (100%) chorismate mutase (100%) "GO:0046417 (48.7%) GO:0009697 (2.6%)" GO:0004106 (48.7%) "chorismate metabolic process (48.7%) salicylic acid biosynthetic process (2.6%)" chorismate mutase activity (48.7%) "IPR002701 (18.4%) IPR006218 (17.5%) IPR052899 (17.5%)" "Chorismate mutase II, prokaryotic-type (18.4%) DAHP synthetase I/KDSA (17.5%) Class-I DAHP synthase (17.5%)" KVVYQEALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (40.5%) IPR011990 (37.8%) IPR050498 (13.5%)" "Tetratricopeptide repeat (40.5%) Tetratricopeptide-like helical domain superfamily (37.8%) Photosystem I assembly protein Ycf3 (13.5%)" FVETVYLPDKDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.192 (90.9%) 2.1.1.- (9.1%)" "23S rRNA (adenine(2503)-C(2))-methyltransferase (90.9%) Methyltransferases (9.1%)" "GO:0030488 (13.3%) GO:0070475 (13.3%)" GO:0005737 (13.3%) "GO:0046872 (13.3%) GO:0051539 (13.3%) GO:0000049 (6.7%)" "tRNA methylation (13.3%) rRNA base methylation (13.3%)" cytoplasm (13.3%) "metal ion binding (13.3%) 4 iron, 4 sulfur cluster binding (13.3%) tRNA binding (6.7%)" "IPR007197 (16.9%) IPR027492 (16.9%) IPR040072 (16.9%)" "Radical SAM (16.9%) Dual-specificity RNA methyltransferase RlmN (16.9%) Methyltransferase (Class A) (16.9%)" CGFTPQYEELEK root 1.11.1.- (100%) Peroxidases (100%) "GO:0034599 (47.8%) GO:0006979 (1.4%)" "GO:0004601 (48.6%) GO:0004602 (0.7%) GO:0047066 (0.7%)" "cellular response to oxidative stress (47.8%) response to oxidative stress (1.4%)" "peroxidase activity (48.6%) glutathione peroxidase activity (0.7%) phospholipid-hydroperoxide glutathione peroxidase activity (0.7%)" "IPR000889 (29.8%) IPR036249 (29.8%) IPR029760 (25%)" "Glutathione peroxidase (29.8%) Thioredoxin-like superfamily (29.8%) Glutathione peroxidase conserved site (25%)" AELNALDKLDYEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.4%) IPR003385 (20.4%) IPR013783 (19.7%)" "Carbohydrate binding module family 20 (20.4%) Glycoside hydrolase, family 77 (20.4%) Immunoglobulin-like fold (19.7%)" VQDSALEELVFTDSLPYTKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.5%) GO:0006164 (11.5%) GO:0009156 (7.7%)" "GO:0002189 (11.5%) GO:0005737 (11.5%)" "GO:0000287 (11.5%) GO:0004749 (11.5%) GO:0005524 (11.5%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.5%) purine nucleotide biosynthetic process (11.5%) ribonucleoside monophosphate biosynthetic process (7.7%)" "ribose phosphate diphosphokinase complex (11.5%) cytoplasm (11.5%)" "magnesium ion binding (11.5%) ribose phosphate diphosphokinase activity (11.5%) ATP binding (11.5%)" "IPR000836 (18.8%) IPR005946 (18.8%) IPR029057 (18.8%)" "Phosphoribosyltransferase domain (18.8%) Ribose-phosphate pyrophosphokinase (18.8%) Phosphoribosyltransferase-like (18.8%)" QNSFFLK root "2.1.1.319 (20%) 2.3.2.27 (20%) 2.4.1.- (20%)" "type I protein arginine methyltransferase (20%) RING-type E3 ubiquitin transferase (20%) Hexosyltransferases (20%)" "GO:0015031 (6.9%) GO:0015679 (2.8%) GO:0060003 (2.8%)" "GO:0009279 (22.9%) GO:0009706 (6.9%) GO:0016020 (6.3%)" "GO:0046914 (2.8%) GO:0016787 (2.1%) GO:0022857 (2.1%)" "protein transport (6.9%) plasma membrane copper ion transport (2.8%) copper ion export (2.8%)" "cell outer membrane (22.9%) chloroplast inner membrane (6.9%) membrane (6.3%)" "transition metal ion binding (2.8%) hydrolase activity (2.1%) transmembrane transporter activity (2.1%)" "IPR000531 (9.5%) IPR023996 (9.5%) IPR012910 (9.2%)" "TonB-dependent receptor-like, beta-barrel (9.5%) TonB-dependent outer membrane protein, SusC/RagA (9.5%) TonB-dependent receptor, plug domain (9.2%)" QLLMFLR root "5.6.2.4 (62.5%) 3.4.24.3 (12.5%) 7.4.2.14 (6.3%)" "DNA 3'-5' helicase (62.5%) microbial collagenase (12.5%) ABC-type antigen peptide transporter (6.3%)" "GO:0006281 (4.3%) GO:0006310 (4.1%) GO:0006260 (3.7%)" "GO:0005737 (4.7%) GO:0016020 (4.4%) GO:0030894 (3.9%)" "GO:0005524 (5.4%) GO:0003677 (4.4%) GO:0016787 (4.4%)" "DNA repair (4.3%) DNA recombination (4.1%) DNA replication (3.7%)" "cytoplasm (4.7%) membrane (4.4%) replisome (3.9%)" "ATP binding (5.4%) DNA binding (4.4%) hydrolase activity (4.4%)" "IPR027417 (4.4%) IPR001650 (3.9%) IPR014001 (3.9%)" "P-loop containing nucleoside triphosphate hydrolase (4.4%) Helicase, C-terminal domain-like (3.9%) Helicase superfamily 1/2, ATP-binding domain (3.9%)" AGTYTLTVK root "2.7.11.1 (87.5%) 3.1.-.- (6.3%) 3.2.1.14 (6.3%)" "non-specific serine/threonine protein kinase (87.5%) Acting on ester bonds (6.3%) chitinase (6.3%)" "GO:0009653 (7.3%) GO:0030154 (7.3%) GO:0050793 (7.3%)" "GO:0031672 (7.3%) GO:0005576 (4%) GO:0031430 (2%)" "GO:0046872 (10%) GO:0004674 (9.3%) GO:0005516 (9.3%)" "anatomical structure morphogenesis (7.3%) cell differentiation (7.3%) regulation of developmental process (7.3%)" "A band (7.3%) extracellular region (4%) M band (2%)" "metal ion binding (10%) protein serine/threonine kinase activity (9.3%) calmodulin binding (9.3%)" "IPR025667 (11.4%) IPR026341 (10.5%) IPR013783 (5.9%)" "SprB repeat (11.4%) T9SS type B sorting domain (10.5%) Immunoglobulin-like fold (5.9%)" KGESLALTLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.4%) IPR019533 (25.4%) IPR019758 (25.4%)" "Peptidase S26A, signal peptidase I (25.4%) Peptidase S26 (25.4%) Peptidase S26A, signal peptidase I, conserved site (25.4%)" MYALVELNGQQFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (16.5%) "GO:0005840 (16.7%) GO:0005737 (16.6%) GO:1990904 (16.5%)" "GO:0003735 (16.5%) GO:0019843 (15.2%) GO:0003723 (1.3%)" translation (16.5%) "ribosome (16.7%) cytoplasm (16.6%) ribonucleoprotein complex (16.5%)" "structural constituent of ribosome (16.5%) rRNA binding (15.2%) RNA binding (1.3%)" "IPR028909 (32%) IPR036164 (32%) IPR001787 (31.9%)" "Large ribosomal subunit protein bL21-like (32%) Large ribosomal subunit protein bL21-like superfamily (32%) Large ribosomal subunit protein bL21 (31.9%)" HLLNTTNSYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005737 (50%) GO:0016881 (50%) cytoplasm (50%) acid-amino acid ligase activity (50%) "IPR004993 (35.1%) IPR055377 (32.4%) IPR055378 (32.4%)" "GH3 family (35.1%) GH3, middle domain (32.4%) GH3, C-terminal domain (32.4%)" NVMMAMPTTLDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.37 (60%) 1.1.1.40 (40%)" "malate dehydrogenase (60%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (40%)" GO:0006108 (34.7%) GO:0016020 (1%) "GO:0016615 (29.7%) GO:0016616 (29.7%) GO:0030060 (3%)" malate metabolic process (34.7%) membrane (1%) "malate dehydrogenase activity (29.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (29.7%) L-malate dehydrogenase (NAD+) activity (3%)" "IPR001236 (16.7%) IPR001557 (16.7%) IPR010945 (16.7%)" "Lactate/malate dehydrogenase, N-terminal (16.7%) L-lactate/malate dehydrogenase (16.7%) Malate dehydrogenase, type 2 (16.7%)" LMMNATLNSGALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.281 (100%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (100%) "GO:0005975 (26.4%) GO:0071555 (26.4%)" "GO:0016758 (26.4%) GO:0016798 (20.8%)" "carbohydrate metabolic process (26.4%) cell wall organization (26.4%)" "hexosyltransferase activity (26.4%) hydrolase activity, acting on glycosyl bonds (20.8%)" "IPR007184 (34%) IPR028583 (34%) IPR023296 (32%)" "Mannoside phosphorylase (34%) 4-O-beta-D-mannosyl-D-glucose phosphorylase (34%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32%)" VPGMTVTTDGSPLGSGTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (6.9%) GO:0009279 (86.2%) GO:0015344 (6.9%) siderophore transmembrane transport (6.9%) cell outer membrane (86.2%) siderophore uptake transmembrane transporter activity (6.9%) "IPR012910 (12.9%) IPR023997 (12.9%) IPR037066 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%) TonB-dependent receptor, plug domain superfamily (12.9%)" ASEVTLMNNYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (84.6%) GO:0015344 (15.4%) cell outer membrane (84.6%) siderophore uptake transmembrane transporter activity (15.4%) "IPR036942 (84.6%) IPR039426 (15.4%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (84.6%) TonB-dependent receptor-like (15.4%)" ADANGNQADMFVCGVNTDKYNGQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (18.8%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (18.8%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" AGSEVSNALVLYNYSDEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (49.1%) GO:0015562 (50.9%) plasma membrane (49.1%) efflux transmembrane transporter activity (50.9%) "IPR003423 (33.7%) IPR050737 (33.7%) IPR010131 (32.6%)" "Outer membrane efflux protein (33.7%) Unknown (33.7%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (32.6%)" AGLLHDLGKVPDEESELPHALYGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.7%) "GO:0005886 (19.1%) GO:0016020 (0.7%)" "GO:0003723 (20.4%) GO:0016787 (20.4%) GO:0004521 (19.1%)" mRNA catabolic process (19.7%) "plasma membrane (19.1%) membrane (0.7%)" "RNA binding (20.4%) hydrolase activity (20.4%) RNA endonuclease activity (19.1%)" "IPR003607 (12.6%) IPR004087 (12.6%) IPR004088 (12.6%)" "HD/PDEase domain (12.6%) K Homology domain (12.6%) K Homology domain, type 1 (12.6%)" YTEASLVK root "5.6.2.1 (98.8%) 5.99.1.2 (1%) 5.6.2.- (0.1%)" "DNA topoisomerase (98.8%) Transferred entry: 5.6.2.1 (1%) Enzymes altering nucleic acid conformation (0.1%)" "GO:0006265 (23.6%) GO:0006351 (0%) GO:0007059 (0%)" "GO:0005694 (5.5%) GO:0016020 (0%) GO:0005737 (0%)" "GO:0003677 (23.6%) GO:0003917 (23.6%) GO:0046872 (18%)" "DNA topological change (23.6%) DNA-templated transcription (0%) chromosome segregation (0%)" "chromosome (5.5%) membrane (0%) cytoplasm (0%)" "DNA binding (23.6%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (23.6%) metal ion binding (18%)" "IPR000380 (7.1%) IPR013497 (7.1%) IPR023405 (7.1%)" "DNA topoisomerase, type IA (7.1%) DNA topoisomerase, type IA, central (7.1%) DNA topoisomerase, type IA, core domain (7.1%)" KVEENNFGLR root 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.5%) GO:0017038 (11.5%) GO:0043952 (11.5%)" "GO:0005886 (11.5%) GO:0005829 (11.5%) GO:0031522 (11.5%)" "GO:0005524 (11.5%) GO:0046872 (7.8%) GO:0004386 (0.2%)" "protein targeting (11.5%) protein import (11.5%) protein transport by the Sec complex (11.5%)" "plasma membrane (11.5%) cytosol (11.5%) cell envelope Sec protein transport complex (11.5%)" "ATP binding (11.5%) metal ion binding (7.8%) helicase activity (0.2%)" "IPR000185 (8%) IPR011116 (8%) IPR014018 (7.9%)" "Protein translocase subunit SecA (8%) SecA Wing/Scaffold (8%) SecA motor DEAD (7.9%)" FCTGTDTSDWEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.2%) IPR032466 (47.8%)" "Uronate isomerase (52.2%) Metal-dependent hydrolase (47.8%)" LGLGGGSVSSVDTGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.6%) GO:0006164 (0.5%)" GO:0005737 (20%) "GO:0004642 (20%) GO:0046872 (19.8%) GO:0005524 (19.7%)" "'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.5%)" cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) metal ion binding (19.8%) ATP binding (19.7%)" "IPR010918 (11.2%) IPR055181 (11.2%) IPR036676 (11.1%)" "PurM-like, C-terminal domain (11.2%) FGAR-AT, PurM N-terminal-like domain (11.2%) PurM-like, C-terminal domain superfamily (11.1%)" GGLSLWPYANYGKPGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.7.1.13 (100%) preQ1 synthase (100%) "GO:0006400 (25%) GO:0008616 (25%)" GO:0005737 (25%) GO:0033739 (25%) "tRNA modification (25%) tRNA queuosine(34) biosynthetic process (25%)" cytoplasm (25%) preQ1 synthase activity (25%) "IPR016856 (25%) IPR029500 (25%) IPR043133 (25%)" "NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 (25%) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF (25%) GTP cyclohydrolase I, C-terminal/NADPH-dependent 7-cyano-7-deazaguanine reductase (25%)" NEGFEVPELNMSAYMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (22.2%) IPR003379 (22.2%) IPR055268 (22.2%)" "Pyruvate carboxyltransferase (22.2%) Carboxylase, conserved domain (22.2%) Pyruvate carboxylase-like (22.2%)" VLPEQNLLLVK Bacteria Bacteria GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000597 (25.9%) IPR009000 (25.9%) IPR019927 (25.9%)" "Large ribosomal subunit protein uL3 (25.9%) Translation protein, beta-barrel domain superfamily (25.9%) Large ribosomal subunit protein uL3, bacteria/organella (25.9%)" NVTWTDALNAEESVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LLEAMQASKPEGLNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009251 (46%) GO:0031222 (2%) GO:0045493 (2%)" "GO:0008422 (46%) GO:0009044 (2%) GO:0046556 (2%)" "glucan catabolic process (46%) arabinan catabolic process (2%) xylan catabolic process (2%)" "beta-glucosidase activity (46%) xylan 1,4-beta-xylosidase activity (2%) alpha-L-arabinofuranosidase activity (2%)" "IPR002772 (13.4%) IPR001764 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase family 3 C-terminal domain (13.4%) Glycoside hydrolase, family 3, N-terminal (12.8%) Fibronectin type III-like domain (12.8%)" MLVNAYLR root "GO:0009225 (3.6%) GO:0055085 (3.6%)" "GO:0009279 (78.6%) GO:0005886 (3.6%) GO:0016020 (3.6%)" "GO:0008460 (3.6%) GO:0015217 (3.6%)" "nucleotide-sugar metabolic process (3.6%) transmembrane transport (3.6%)" "cell outer membrane (78.6%) plasma membrane (3.6%) membrane (3.6%)" "dTDP-glucose 4,6-dehydratase activity (3.6%) ADP transmembrane transporter activity (3.6%)" "IPR012910 (14.4%) IPR023996 (14.4%) IPR023997 (14.4%)" "TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.4%)" LFTDLDKETLDALVEEHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.9%) GO:0005829 (16.9%) "GO:0003723 (16.9%) GO:0004831 (16.9%) GO:0005524 (16.9%)" tyrosyl-tRNA aminoacylation (16.9%) cytosol (16.9%) "RNA binding (16.9%) tyrosine-tRNA ligase activity (16.9%) ATP binding (16.9%)" "IPR002305 (12.8%) IPR002307 (12.8%) IPR014729 (12.8%)" "Aminoacyl-tRNA synthetase, class Ic (12.8%) Tyrosine-tRNA ligase (12.8%) Rossmann-like alpha/beta/alpha sandwich fold (12.8%)" AVLNALGYEPANANLQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (81.8%) IPR008160 (18.2%)" "Domain of unknown function DUF4988 (81.8%) Collagen triple helix repeat (18.2%)" AAQMDEWFSGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.2.1.1 (97.1%) 2.2.1.- (2.9%)" "transketolase (97.1%) Transketolases and transaldolases (2.9%)" GO:0006098 (24.8%) GO:0005829 (24.8%) "GO:0004802 (24.8%) GO:0046872 (24.8%) GO:0003863 (0.8%)" pentose-phosphate shunt (24.8%) cytosol (24.8%) "transketolase activity (24.8%) metal ion binding (24.8%) branched-chain 2-oxo acid dehydrogenase activity (0.8%)" "IPR005475 (12.8%) IPR020826 (12.8%) IPR029061 (12.8%)" "Transketolase-like, pyrimidine-binding domain (12.8%) Transketolase binding site (12.8%) Thiamin diphosphate-binding fold (12.8%)" YNYAEYPGNPNGSDYNVAGLCSADGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.6%) GO:0006164 (0.7%)" GO:0005737 (20.3%) "GO:0004642 (20.3%) GO:0005524 (19.6%) GO:0046872 (19.6%)" "'de novo' IMP biosynthetic process (19.6%) purine nucleotide biosynthetic process (0.7%)" cytoplasm (20.3%) "phosphoribosylformylglycinamidine synthase activity (20.3%) ATP binding (19.6%) metal ion binding (19.6%)" "IPR010918 (11.3%) IPR029062 (11.3%) IPR055181 (11.3%)" "PurM-like, C-terminal domain (11.3%) Class I glutamine amidotransferase-like (11.3%) FGAR-AT, PurM N-terminal-like domain (11.3%)" FAGFFQSEEELKNSPDQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" TNGNDVVLVDTAGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.4 (100%) signal-recognition-particle GTPase (100%) GO:0006614 (20.2%) "GO:0048500 (19.3%) GO:0005786 (0.9%)" "GO:0003924 (20.2%) GO:0005525 (20.2%) GO:0008312 (18.3%)" SRP-dependent cotranslational protein targeting to membrane (20.2%) "signal recognition particle (19.3%) signal recognition particle, endoplasmic reticulum targeting (0.9%)" "GTPase activity (20.2%) GTP binding (20.2%) 7S RNA binding (18.3%)" "IPR000897 (11.5%) IPR003593 (11.5%) IPR022941 (11.5%)" "Signal recognition particle, SRP54 subunit, GTPase domain (11.5%) AAA+ ATPase domain (11.5%) Signal recognition particle, SRP54 subunit (11.5%)" VSAAVHTYASSEVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (33.3%) IPR025112 (33.3%) IPR038653 (33.3%)" "Lipocalin-like domain (33.3%) Putative carbohydrate metabolism domain (33.3%) Putative carbohydrate metabolism domain superfamily (33.3%)" LLDGQVADGFFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (96.9%) GO:0016787 (3.1%) membrane (96.9%) hydrolase activity (3.1%) "IPR003607 (16.7%) IPR006674 (16.7%) IPR006675 (16.7%)" "HD/PDEase domain (16.7%) HD domain (16.7%) HDIG domain (16.7%)" NLGSLADMAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" QFNLNAVR root 3.2.1.23 (100%) beta-galactosidase (100%) "GO:0005990 (25.1%) GO:0000272 (0.1%)" "GO:0009341 (25.1%) GO:0005576 (0.1%)" "GO:0004565 (25.1%) GO:0030246 (24.5%) GO:0016757 (0.1%)" "lactose catabolic process (25.1%) polysaccharide catabolic process (0.1%)" "beta-galactosidase complex (25.1%) extracellular region (0.1%)" "beta-galactosidase activity (25.1%) carbohydrate binding (24.5%) glycosyltransferase activity (0.1%)" "IPR006103 (7%) IPR050347 (7%) IPR006101 (7%)" "Glycoside hydrolase family 2, catalytic domain (7%) Bacterial Beta-galactosidase (7%) Glycoside hydrolase, family 2 (7%)" TVSQETNQNLCATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20%) IPR011542 (20%) IPR037284 (20%)" "SUF system FeS cluster assembly, SufBD core domain (20%) SUF system FeS cluster assembly, SufD (20%) SUF system FeS cluster assembly, SufBD superfamily (20%)" TPPAAVQLK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000911 (14.7%) IPR006519 (14.7%) IPR020783 (14.7%)" "Ribosomal protein uL11 (14.7%) Large ribosomal subunit protein uL11, bacteria (14.7%) Large ribosomal subunit protein uL11, C-terminal (14.7%)" FTSVDDLK root "2.7.7.7 (33.3%) 3.6.4.12 (33.3%) 4.2.1.17 (33.3%)" "DNA-directed DNA polymerase (33.3%) DNA helicase (33.3%) enoyl-CoA hydratase (33.3%)" "GO:0000045 (2.4%) GO:0000422 (2.4%) GO:0006261 (2.4%)" "GO:0005634 (7.3%) GO:0005886 (4.9%) GO:0000785 (2.4%)" "GO:0003676 (4.9%) GO:0003677 (4.9%) GO:0042910 (4.9%)" "autophagosome assembly (2.4%) autophagy of mitochondrion (2.4%) DNA-templated DNA replication (2.4%)" "nucleus (7.3%) plasma membrane (4.9%) chromatin (2.4%)" "nucleic acid binding (4.9%) DNA binding (4.9%) xenobiotic transmembrane transporter activity (4.9%)" "IPR002539 (21.3%) IPR029069 (21.3%) IPR039375 (21.3%)" "MaoC-like dehydratase domain (21.3%) HotDog domain superfamily (21.3%) Nodulation protein N-like (21.3%)" KPNLPSSGNFQPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" FLEELLTK root "4.2.1.11 (68.4%) 4.2.1.49 (10.5%) 2.3.2.26 (3.5%)" "phosphopyruvate hydratase (68.4%) urocanate hydratase (10.5%) HECT-type E3 ubiquitin transferase (3.5%)" "GO:0072344 (7.3%) GO:0006096 (3%) GO:0030520 (2.3%)" "GO:0180022 (7.3%) GO:0005634 (6.6%) GO:0005829 (5%)" "GO:0008270 (7.5%) GO:0000287 (3%) GO:0004634 (2.9%)" "rescue of stalled ribosome (7.3%) glycolytic process (3%) estrogen receptor signaling pathway (2.3%)" "RQC-trigger complex (7.3%) nucleus (6.6%) cytosol (5%)" "zinc ion binding (7.5%) magnesium ion binding (3%) phosphopyruvate hydratase activity (2.9%)" "IPR056994 (9.7%) IPR039128 (9.6%) IPR056993 (8.5%)" "Activating signal cointegrator 1, N-terminal (9.7%) Activating signal cointegrator 1-like (9.6%) Activating signal cointegrator 1, third domain (8.5%)" NLQEAFAGESQAR Bacteria Bacteria "1.11.1.1 (96.4%) 1.14.13.81 (3.6%)" "NADH peroxidase (96.4%) magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase (3.6%)" "GO:0005506 (39.2%) GO:0016491 (25.4%) GO:0010181 (13.1%)" "iron ion binding (39.2%) oxidoreductase activity (25.4%) FMN binding (13.1%)" "IPR009040 (13.3%) IPR003251 (13.2%) IPR009078 (13.2%)" "Ferritin-like diiron domain (13.3%) Rubrerythrin, diiron-binding domain (13.2%) Ferritin-like superfamily (13.2%)" ETGMVPVFFNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "4.1.2.14 (52.4%) 4.1.3.16 (47.6%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (52.4%) 4-hydroxy-2-oxoglutarate aldolase (47.6%)" "GO:0016829 (68.2%) GO:0008675 (18.2%) GO:0008700 (13.6%)" "lyase activity (68.2%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (18.2%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (13.6%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" SRPLHGENQNSVLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) "IPR006598 (50%) IPR051091 (50%)" "Glycosyl transferase CAP10 domain (50%) Protein O-Glucosyltransferase/Glycosyltransferase 90 (50%)" LETVEEAGLKEGDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14.2%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14.2%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR003029 (7.9%) IPR012162 (7.9%) IPR001247 (7.8%)" "S1 domain (7.9%) Polyribonucleotide nucleotidyltransferase (7.9%) Exoribonuclease, phosphorolytic domain 1 (7.8%)" LNLHELYGEFGGK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.8%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.8%)" RFELDELQSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.5%) GO:0006261 (12.4%)" "GO:0005737 (12.5%) GO:0009330 (12.5%) GO:0005694 (12.4%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.4%)" "DNA topological change (12.5%) DNA-templated DNA replication (12.4%)" "cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%) chromosome (12.4%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.4%)" "IPR002205 (12.6%) IPR006691 (12.6%) IPR050220 (12.6%)" "DNA topoisomerase, type IIA, domain A (12.6%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.6%) Type II DNA Topoisomerases (12.6%)" VQLPEVTATGTALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLKPLEYYQQK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0016757 (66.7%) GO:0016740 (20%) GO:0004044 (13.3%)" "glycosyltransferase activity (66.7%) transferase activity (20%) amidophosphoribosyltransferase activity (13.3%)" "IPR017932 (25.6%) IPR029055 (25%) IPR029057 (25%)" "Glutamine amidotransferase type 2 domain (25.6%) Nucleophile aminohydrolases, N-terminal (25%) Phosphoribosyltransferase-like (25%)" TALAVDTLLNQK root "7.1.2.2 (98.4%) 3.6.3.14 (1.6%)" "H(+)-transporting two-sector ATPase (98.4%) Transferred entry: 7.1.2.2 (1.6%)" "GO:0015986 (0%) GO:0002926 (0%) GO:0007186 (0%)" "GO:0045259 (19.7%) GO:0005886 (10.8%) GO:0005743 (3.3%)" "GO:0005524 (19.7%) GO:0046933 (19.7%) GO:0043531 (19.6%)" "proton motive force-driven ATP synthesis (0%) tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation (0%) G protein-coupled receptor signaling pathway (0%)" "proton-transporting ATP synthase complex (19.7%) plasma membrane (10.8%) mitochondrial inner membrane (3.3%)" "ATP binding (19.7%) proton-transporting ATP synthase activity, rotational mechanism (19.7%) ADP binding (19.6%)" "IPR000194 (10.8%) IPR005294 (10.8%) IPR027417 (10.7%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.8%) ATP synthase, F1 complex, alpha subunit (10.8%) P-loop containing nucleoside triphosphate hydrolase (10.7%)" SPYEFEVANK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR023614 (100%) Porin domain superfamily (100%) LHLVAMGLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (32.2%) GO:0051536 (1.1%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (32.2%) iron-sulfur cluster binding (1.1%)" "IPR003741 (14.4%) IPR004452 (14.4%) IPR017896 (14.4%)" "LUD domain (14.4%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.4%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.4%)" VQHGNYVWAPSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" LVMLMTGK Bacteria Bacteria "6.1.1.6 (96.7%) 2.1.2.3 (1.1%) 3.5.4.10 (1.1%)" "lysine--tRNA ligase (96.7%) phosphoribosylaminoimidazolecarboxamide formyltransferase (1.1%) IMP cyclohydrolase (1.1%)" "GO:0006430 (16.2%) GO:0006189 (0.2%) GO:0006422 (0.2%)" "GO:0005829 (16.4%) GO:0005886 (0.4%) GO:0005737 (0.2%)" "GO:0005524 (16.4%) GO:0000049 (16.2%) GO:0004824 (16.2%)" "lysyl-tRNA aminoacylation (16.2%) 'de novo' IMP biosynthetic process (0.2%) aspartyl-tRNA aminoacylation (0.2%)" "cytosol (16.4%) plasma membrane (0.4%) cytoplasm (0.2%)" "ATP binding (16.4%) tRNA binding (16.2%) lysine-tRNA ligase activity (16.2%)" "IPR004364 (12.1%) IPR006195 (12.1%) IPR002313 (11.8%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (12.1%) Aminoacyl-tRNA synthetase, class II (12.1%) Lysine-tRNA ligase, class II (11.8%)" ALYQLQTTLSALDEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" LQHPEKLEPFPTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (71.4%) IPR008160 (28.6%)" "Domain of unknown function DUF4988 (71.4%) Collagen triple helix repeat (28.6%)" GSLLTNLDQSFQGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.9%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.9%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" DLVNVQALAQYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (3.7%) GO:0016020 (92.6%) GO:0008233 (3.7%) proteolysis (3.7%) membrane (92.6%) peptidase activity (3.7%) "IPR006665 (27.2%) IPR050330 (27.2%) IPR036737 (25%)" "OmpA-like domain (27.2%) Bacterial Outer Membrane Structural/Functional (27.2%) OmpA-like domain superfamily (25%)" YNADGTPKPDFVMNDPSYSGVLLVAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" YADALLLK root "2.7.11.25 (33.3%) 2.7.13.3 (33.3%) 6.1.1.17 (33.3%)" "mitogen-activated protein kinase kinase kinase (33.3%) histidine kinase (33.3%) glutamate--tRNA ligase (33.3%)" "GO:0032259 (7.7%) GO:0001714 (2.2%) GO:0008356 (2.2%)" "GO:0009279 (20.9%) GO:0016020 (2.2%) GO:0005737 (1.1%)" "GO:0005524 (7.7%) GO:0008171 (7.7%) GO:0016787 (5.5%)" "methylation (7.7%) endodermal cell fate specification (2.2%) asymmetric cell division (2.2%)" "cell outer membrane (20.9%) membrane (2.2%) cytoplasm (1.1%)" "ATP binding (7.7%) O-methyltransferase activity (7.7%) hydrolase activity (5.5%)" "IPR011990 (13.9%) IPR012944 (13.2%) IPR033985 (13.2%)" "Tetratricopeptide-like helical domain superfamily (13.9%) RagB/SusD domain (13.2%) SusD-like, N-terminal (13.2%)" VTDAEADALVEEYKK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" VLVPLCLR root "2.3.2.15 (66.7%) 5.4.2.- (33.3%)" "glutathione gamma-glutamylcysteinyltransferase (66.7%) Phosphotransferases (phosphomutases) (33.3%)" "GO:0005975 (3.3%) GO:0006166 (3.3%) GO:0006075 (0.2%)" "GO:0005634 (27.3%) GO:0016020 (0.5%) GO:0005886 (0.3%)" "GO:0000978 (27.3%) GO:0000981 (27.3%) GO:0000287 (3.3%)" "carbohydrate metabolic process (3.3%) purine ribonucleoside salvage (3.3%) (1->3)-beta-D-glucan biosynthetic process (0.2%)" "nucleus (27.3%) membrane (0.5%) plasma membrane (0.3%)" "RNA polymerase II cis-regulatory region sequence-specific DNA binding (27.3%) DNA-binding transcription factor activity, RNA polymerase II-specific (27.3%) magnesium ion binding (3.3%)" "IPR001356 (20.2%) IPR009057 (20.2%) IPR051440 (20.1%)" "Homeodomain (20.2%) Homedomain-like superfamily (20.2%) Goosecoid-like homeobox (20.1%)" GAFTGEVSAEMVK root 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (13.4%) GO:0006096 (13.4%) GO:0019563 (13.4%)" "GO:0005829 (13.4%) GO:0016020 (10%)" GO:0004807 (13.4%) "gluconeogenesis (13.4%) glycolytic process (13.4%) glycerol catabolic process (13.4%)" "cytosol (13.4%) membrane (10%)" triose-phosphate isomerase activity (13.4%) "IPR000652 (17.7%) IPR020861 (17.7%) IPR022896 (17.4%)" "Triosephosphate isomerase (17.7%) Triosephosphate isomerase, active site (17.7%) Triosephosphate isomerase, bacterial/eukaryotic (17.4%)" YTFGWTNTFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LDNLSLSYNVGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR039426 (12.2%) IPR000531 (11.8%) IPR012910 (11.8%)" "TonB-dependent receptor-like (12.2%) TonB-dependent receptor-like, beta-barrel (11.8%) TonB-dependent receptor, plug domain (11.8%)" TMLFYESPYR Bacteria Bacteria 2.1.1.198 (100%) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (100%) "GO:0032259 (3.2%) GO:0006364 (2.5%)" "GO:0005737 (46.4%) GO:0016020 (0.7%)" "GO:0070677 (43.9%) GO:0008168 (3.2%)" "methylation (3.2%) rRNA processing (2.5%)" "cytoplasm (46.4%) membrane (0.7%)" "rRNA (cytosine-2'-O-)-methyltransferase activity (43.9%) methyltransferase activity (3.2%)" "IPR008189 (16.9%) IPR000878 (16.8%) IPR014776 (16.7%)" "rRNA small subunit methyltransferase I (16.9%) Tetrapyrrole methylase (16.8%) Tetrapyrrole methylase, subdomain 2 (16.7%)" FATDTDEELEVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (32.3%) GO:0006730 (1.1%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (32.3%) one-carbon metabolic process (1.1%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.4%) IPR020628 (33.3%) IPR027417 (32.2%)" "Formate-tetrahydrofolate ligase, FTHFS (34.4%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33.3%) P-loop containing nucleoside triphosphate hydrolase (32.2%)" EDLDPFEALLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25.2%) GO:0016301 (25.2%) GO:0050242 (25.2%)" "ATP binding (25.2%) kinase activity (25.2%) pyruvate, phosphate dikinase activity (25.2%)" "IPR002192 (10.2%) IPR010121 (10.2%) IPR013815 (10.2%)" "Pyruvate phosphate dikinase, AMP/ATP-binding (10.2%) Pyruvate, phosphate dikinase (10.2%) ATP-grasp fold, subdomain 1 (10.2%)" LGFLPGDMKDK Bacteria Bacteria "GO:0005829 (48.9%) GO:0016020 (0.1%)" "GO:0005524 (48.9%) GO:0003723 (1.9%) GO:0004386 (0.2%)" "cytosol (48.9%) membrane (0.1%)" "ATP binding (48.9%) RNA binding (1.9%) helicase activity (0.2%)" "IPR003714 (32.9%) IPR051451 (32.9%) IPR027417 (32.8%)" "PhoH-like protein (32.9%) PhoH2-like (32.9%) P-loop containing nucleoside triphosphate hydrolase (32.8%)" SLNEVVVLGYGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (12.9%) IPR039426 (12.9%) IPR000531 (12.4%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent receptor-like (12.9%) TonB-dependent receptor-like, beta-barrel (12.4%)" YAMVGFR root "3.2.1.1 (63.2%) 5.3.1.8 (15.8%) 7.1.1.- (15.8%)" "alpha-amylase (63.2%) mannose-6-phosphate isomerase (15.8%) Hydron translocation or charge separation linked to oxidoreductase reactions (15.8%)" "GO:0005975 (11.7%) GO:0009298 (2.2%) GO:0042773 (2.2%)" "GO:0005829 (2.2%) GO:0005886 (2.2%) GO:0012505 (2.2%)" "GO:0016740 (46%) GO:0004556 (8.8%) GO:0046872 (8.8%)" "carbohydrate metabolic process (11.7%) GDP-mannose biosynthetic process (2.2%) ATP synthesis coupled electron transport (2.2%)" "cytosol (2.2%) plasma membrane (2.2%) endomembrane system (2.2%)" "transferase activity (46%) alpha-amylase activity (8.8%) metal ion binding (8.8%)" "IPR029044 (55.2%) IPR005835 (10.4%) IPR006047 (4.7%)" "Nucleotide-diphospho-sugar transferases (55.2%) Nucleotidyl transferase domain (10.4%) Glycosyl hydrolase family 13, catalytic domain (4.7%)" LLNLCSMMSELGR Bacteria Bacteria "1.1.1.69 (95.9%) 1.1.1.125 (1.9%) 1.1.1.391 (1.1%)" "gluconate 5-dehydrogenase (95.9%) 2-deoxy-D-gluconate 3-dehydrogenase (1.9%) 3beta-hydroxycholanate 3-dehydrogenase (NAD(+)) (1.1%)" "GO:0008206 (29.3%) GO:0006629 (1.8%) GO:0032787 (1.8%)" GO:0016020 (2.5%) "GO:0008874 (26.6%) GO:0016616 (21.9%) GO:0016491 (14%)" "bile acid metabolic process (29.3%) lipid metabolic process (1.8%) monocarboxylic acid metabolic process (1.8%)" membrane (2.5%) "gluconate 5-dehydrogenase activity (26.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (21.9%) oxidoreductase activity (14%)" "IPR002347 (32.6%) IPR020904 (32.5%) IPR036291 (32.5%)" "Short-chain dehydrogenase/reductase SDR (32.6%) Short-chain dehydrogenase/reductase, conserved site (32.5%) NAD(P)-binding domain superfamily (32.5%)" NYGDAYLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (52.3%) IPR011990 (47.7%)" "Tetratricopeptide repeat (52.3%) Tetratricopeptide-like helical domain superfamily (47.7%)" NTPYAAQMAAEDCAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (19.9%) "GO:0005840 (20.3%) GO:1990904 (19.9%)" "GO:0003735 (19.9%) GO:0019843 (19.9%)" translation (19.9%) "ribosome (20.3%) ribonucleoprotein complex (19.9%)" "structural constituent of ribosome (19.9%) rRNA binding (19.9%)" "IPR001971 (25%) IPR018102 (25%) IPR019981 (25%)" "Small ribosomal subunit protein uS11 (25%) Small ribosomal subunit protein uS11, conserved site (25%) Small ribosomal subunit protein uS11, bacteria (25%)" MLQEAVDSLFDNSR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) "GO:0000428 (16.9%) GO:0031981 (0.1%)" "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (15.5%)" DNA-templated transcription (16.9%) "DNA-directed RNA polymerase complex (16.9%) nuclear lumen (0.1%)" "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (15.5%)" "IPR007080 (9%) IPR045867 (9%) IPR006592 (9%)" "RNA polymerase Rpb1, domain 1 (9%) DNA-directed RNA polymerase, subunit beta-prime (9%) RNA polymerase, N-terminal (9%)" VLEMGFLK root 2.7.13.3 (100%) histidine kinase (100%) "GO:0005886 (23.9%) GO:0016020 (1.3%)" "GO:0046914 (24.5%) GO:0005525 (23.9%) GO:0015093 (23.9%)" "plasma membrane (23.9%) membrane (1.3%)" "transition metal ion binding (24.5%) GTP binding (23.9%) ferrous iron transmembrane transporter activity (23.9%)" "IPR007167 (8.9%) IPR003373 (8.7%) IPR005225 (8.7%)" "Ferrous iron transporter FeoA-like domain (8.9%) Ferrous iron transport protein B (8.7%) Small GTP-binding domain (8.7%)" AHPADGAGQGLLK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.4.1.1 (89.3%) 2.4.1.8 (10.7%)" "glycogen phosphorylase (89.3%) maltose phosphorylase (10.7%)" "GO:0005975 (32.6%) GO:0005978 (0.4%)" "GO:0030170 (33%) GO:0008184 (32.8%) GO:0050082 (0.6%)" "carbohydrate metabolic process (32.6%) glycogen biosynthetic process (0.4%)" "pyridoxal phosphate binding (33%) glycogen phosphorylase activity (32.8%) maltose phosphorylase activity (0.6%)" "IPR011834 (25.1%) IPR052182 (25.1%) IPR000811 (24.9%)" "Alpha-glucan phosphorylase (25.1%) Glycogen_Maltodextrin_Phosphorylase (25.1%) Glycosyl transferase, family 35 (24.9%)" KAEDGELYLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25.1%) GO:0022625 (25.1%) "GO:0003735 (25.1%) GO:0019843 (24.6%)" translation (25.1%) cytosolic large ribosomal subunit (25.1%) "structural constituent of ribosome (25.1%) rRNA binding (24.6%)" "IPR001063 (25.1%) IPR036394 (25.1%) IPR047867 (25.1%)" "Large ribosomal subunit protein uL22 (25.1%) Ribosomal protein uL22 superfamily (25.1%) Large ribosomal subunit protein uL22, bacteria/organella (25.1%)" EGQPETCQLTAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" SGYSANAELVLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" YNEDYVEAQMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030245 (24.3%) GO:0000272 (1.4%)" "GO:0005576 (24.3%) GO:0009986 (24.3%)" "GO:0008422 (24.3%) GO:0004553 (1.4%)" "cellulose catabolic process (24.3%) polysaccharide catabolic process (1.4%)" "extracellular region (24.3%) cell surface (24.3%)" "beta-glucosidase activity (24.3%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.4%)" "IPR001547 (21.7%) IPR024361 (20.5%) IPR050386 (20.5%)" "Glycoside hydrolase, family 5 (21.7%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (20.5%) Glycosyl Hydrolase 5 (Cellulase A) (20.5%)" GLVSSPEQLLNGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (1.5%) GO:0009279 (97.1%) GO:0015344 (1.5%) siderophore transmembrane transport (1.5%) cell outer membrane (97.1%) siderophore uptake transmembrane transporter activity (1.5%) "IPR012910 (11.6%) IPR023996 (11.6%) IPR023997 (11.6%)" "TonB-dependent receptor, plug domain (11.6%) TonB-dependent outer membrane protein, SusC/RagA (11.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (11.6%)" YEYEAAHGTVTR Bacteria Bacteria "1.1.1.42 (99.4%) 2.1.1.33 (0.6%)" "isocitrate dehydrogenase (NADP(+)) (99.4%) tRNA (guanine(46)-N(7))-methyltransferase (0.6%)" "GO:0006099 (20%) GO:0006102 (20%)" "GO:0004450 (20%) GO:0000287 (19.8%) GO:0051287 (19.8%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "isocitrate dehydrogenase (NADP+) activity (20%) magnesium ion binding (19.8%) NAD binding (19.8%)" "IPR004790 (33.3%) IPR024084 (33.3%) IPR019818 (32.8%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (32.8%)" MTYDLNYLELPAVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025665 (88%) IPR036709 (12%)" "Outer membrane protein, beta-barrel domain 2 (88%) Autotransporter beta-domain superfamily (12%)" LLAGMEFSKDELVNCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (33.3%) "GO:0016639 (33.3%) GO:0051536 (33.3%)" glutamate biosynthetic process (33.3%) "oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (33.3%) iron-sulfur cluster binding (33.3%)" "IPR006005 (16.7%) IPR009051 (16.7%) IPR023753 (16.7%)" "Glutamate synthase, NADH/NADPH, small subunit 1 (16.7%) Alpha-helical ferredoxin (16.7%) FAD/NAD(P)-binding domain (16.7%)" VTAPLFVLK Pseudomonadati Bacteria Pseudomonadati 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.7%) GO:0006529 (1.3%)" "GO:0005829 (24.8%) GO:0005737 (0.1%)" "GO:0004071 (25%) GO:0005524 (23.7%) GO:0000166 (1.2%)" "L-asparagine biosynthetic process (23.7%) obsolete asparagine biosynthetic process (1.3%)" "cytosol (24.8%) cytoplasm (0.1%)" "aspartate-ammonia ligase activity (25%) ATP binding (23.7%) nucleotide binding (1.2%)" "IPR004618 (33.7%) IPR045864 (33.3%) IPR006195 (33%)" "Aspartate--ammonia ligase (33.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (33.3%) Aminoacyl-tRNA synthetase, class II (33%)" TTLSNNNETNWTWSNTAQYVTQLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" MSLTYLR root "3.4.21.107 (25%) 3.4.23.36 (25%) 4.3.1.1 (18.8%)" "peptidase Do (25%) signal peptidase II (25%) aspartate ammonia-lyase (18.8%)" "GO:0006508 (14.6%) GO:0006099 (1.7%) GO:0006531 (1.7%)" "GO:0016020 (9.9%) GO:0005886 (6.9%) GO:0005829 (1.7%)" "GO:0004252 (13.3%) GO:0015171 (4.7%) GO:0003677 (3.9%)" "proteolysis (14.6%) tricarboxylic acid cycle (1.7%) aspartate metabolic process (1.7%)" "membrane (9.9%) plasma membrane (6.9%) cytosol (1.7%)" "serine-type endopeptidase activity (13.3%) amino acid transmembrane transporter activity (4.7%) DNA binding (3.9%)" "IPR001478 (7.5%) IPR025926 (7.5%) IPR001940 (7.3%)" "PDZ domain (7.5%) PDZ-like domain (7.5%) Peptidase S1C (7.3%)" KQVALGSNDWSDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) ENLAQLDEATLNDVFANVPHYDLDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.9%) GO:0005829 (16.9%) "GO:0003723 (16.9%) GO:0004831 (16.9%) GO:0005524 (16.9%)" tyrosyl-tRNA aminoacylation (16.9%) cytosol (16.9%) "RNA binding (16.9%) tyrosine-tRNA ligase activity (16.9%) ATP binding (16.9%)" "IPR002305 (12.8%) IPR002307 (12.8%) IPR014729 (12.8%)" "Aminoacyl-tRNA synthetase, class Ic (12.8%) Tyrosine-tRNA ligase (12.8%) Rossmann-like alpha/beta/alpha sandwich fold (12.8%)" SYHTVMLPFTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016787 (50.8%) GO:0030246 (49.2%)" "hydrolase activity (50.8%) carbohydrate binding (49.2%)" "IPR019563 (14.7%) IPR029483 (14.7%) IPR029486 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%)" ETGAHALNTYPGTWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.5%) IPR002772 (11.5%) IPR019800 (11.5%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Glycoside hydrolase family 3 C-terminal domain (11.5%) Glycoside hydrolase, family 3, active site (11.5%)" WVDMVFAGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0015031 (18.8%) GO:0055085 (18.8%) GO:0015891 (12.5%)" "GO:0098797 (18.8%) GO:0030288 (12.5%)" GO:0031992 (18.8%) "protein transport (18.8%) transmembrane transport (18.8%) siderophore transport (12.5%)" "plasma membrane protein complex (18.8%) outer membrane-bounded periplasmic space (12.5%)" energy transducer activity (18.8%) "IPR006260 (27.3%) IPR037682 (27.3%) IPR051045 (27.3%)" "TonB/TolA, C-terminal (27.3%) TonB, C-terminal (27.3%) TonB-dependent transporter energy transducer (27.3%)" VGPGSQLYVWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (31.9%) GO:0051536 (1.4%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (31.9%) iron-sulfur cluster binding (1.4%)" "IPR003741 (14.5%) IPR004452 (14.5%) IPR017896 (14.5%)" "LUD domain (14.5%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.5%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.5%)" DGQLWSMNPDGTGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.4%) IPR001375 (20.2%) IPR011042 (20.2%)" "WD40-like beta-propeller (21.4%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20.2%) Six-bladed beta-propeller, TolB-like (20.2%)" GDGTVYVPAYAAQSYNKDESLGGSDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.5%) IPR008969 (11.5%) IPR012910 (11.5%)" "TonB-dependent receptor-like, beta-barrel (11.5%) Carboxypeptidase-like, regulatory domain superfamily (11.5%) TonB-dependent receptor, plug domain (11.5%)" AQLLDAVKDVDAMLLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.7%) GO:0033711 (2.3%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.7%) 4-phosphoerythronate dehydrogenase activity (2.3%)" "IPR006139 (31.4%) IPR006140 (31.4%) IPR036291 (31.4%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (31.4%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (31.4%) NAD(P)-binding domain superfamily (31.4%)" LLADHEAELEKDAE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25.4%) "GO:0003746 (25.4%) GO:0005525 (25.4%) GO:0003924 (23.9%)" ribosome disassembly (25.4%) "translation elongation factor activity (25.4%) GTP binding (25.4%) GTPase activity (23.9%)" "IPR000640 (8.1%) IPR005517 (8.1%) IPR035649 (8.1%)" "Elongation factor EFG, domain V-like (8.1%) Translation elongation factor EFG/EF2, domain IV (8.1%) EFG, domain V (8.1%)" VEGTPFDFR root "5.1.3.3 (92.1%) 5.1.3.- (7.9%)" "aldose 1-epimerase (92.1%) Acting on carbohydrates and derivatives (7.9%)" "GO:0006006 (21%) GO:0033499 (21%)" "GO:0005737 (16%) GO:0016020 (0.2%)" "GO:0004034 (21%) GO:0030246 (20.9%)" "glucose metabolic process (21%) galactose catabolic process via UDP-galactose, Leloir pathway (21%)" "cytoplasm (16%) membrane (0.2%)" "aldose 1-epimerase activity (21%) carbohydrate binding (20.9%)" "IPR008183 (18.7%) IPR011013 (18.6%) IPR014718 (18.6%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (18.7%) Galactose mutarotase-like domain superfamily (18.6%) Glycoside hydrolase-type carbohydrate-binding (18.6%)" NLYSTLNAK Bacteria Bacteria GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.1%) IPR023996 (15.1%) IPR023997 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent outer membrane protein, SusC/RagA (15.1%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.1%)" LGDVEYQGDGNK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005737 (99.8%) GO:0003729 (0.2%) cytoplasm (99.8%) mRNA binding (0.2%) "IPR007557 (49.9%) IPR047767 (49.9%) IPR020018 (0.1%)" "PSP1, C-terminal (49.9%) PSP1-like (49.9%) Gliding motility-associated lipoprotein, GldH (0.1%)" LYAEMVGEGESADAYHLTASHPEGLGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.7%) IPR014030 (14.7%) IPR020841 (14.7%)" "Beta-ketoacyl synthase (14.7%) Beta-ketoacyl synthase-like, N-terminal (14.7%) Polyketide synthase, beta-ketoacyl synthase domain (14.7%)" DMVDGLNNSGLLPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25%) GO:0005829 (25%) "GO:0008733 (25%) GO:0030145 (25%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25%) cytosol (25%) "L-arabinose isomerase activity (25%) manganese ion binding (25%)" "IPR003762 (14.6%) IPR024664 (14.6%) IPR055389 (14.6%)" "L-arabinose isomerase (14.6%) L-arabinose isomerase, C-terminal (14.6%) L-arabinose isomerase, N-terminal domain (14.6%)" EAKDLVDGAPSTLK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20%) IPR008932 (20%) IPR013823 (20%)" "Large ribosomal subunit protein bL12 (20%) Large ribosomal subunit protein bL12, oligomerization (20%) Large ribosomal subunit protein bL12, C-terminal (20%)" VADLLER root "2.7.7.7 (40.5%) 7.6.2.11 (5.3%) 2.7.1.49 (2.7%)" "DNA-directed DNA polymerase (40.5%) ABC-type polyamine transporter (5.3%) hydroxymethylpyrimidine kinase (2.7%)" "GO:0006261 (3.2%) GO:0034472 (1.4%) GO:0015833 (0.7%)" "GO:0009360 (3.1%) GO:0005886 (2.7%) GO:0005737 (2.2%)" "GO:0005524 (8.5%) GO:0046872 (4.6%) GO:0003677 (4.6%)" "DNA-templated DNA replication (3.2%) snRNA 3'-end processing (1.4%) peptide transport (0.7%)" "DNA polymerase III complex (3.1%) plasma membrane (2.7%) cytoplasm (2.2%)" "ATP binding (8.5%) metal ion binding (4.6%) DNA binding (4.6%)" "IPR027417 (4.7%) IPR003593 (3.5%) IPR050238 (2%)" "P-loop containing nucleoside triphosphate hydrolase (4.7%) AAA+ ATPase domain (3.5%) DNA Replication and Repair Clamp Loader Complex (2%)" TLSETVDMDVLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.5%) IPR012944 (34.5%) IPR033985 (31%)" "Tetratricopeptide-like helical domain superfamily (34.5%) RagB/SusD domain (34.5%) SusD-like, N-terminal (31%)" YLVGMATQGFANYLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.1%) IPR016066 (14.1%) IPR005845 (13.8%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.1%) Alpha-D-phosphohexomutase, conserved site (14.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (13.8%)" TYAETSDATYAGEVNQPTAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.1%) IPR033985 (35.1%) IPR011990 (29.7%)" "RagB/SusD domain (35.1%) SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (29.7%)" LPLTFYK root "3.2.1.21 (56.4%) 3.2.1.37 (33.3%) 2.3.2.26 (5.1%)" "beta-glucosidase (56.4%) xylan 1,4-beta-xylosidase (33.3%) HECT-type E3 ubiquitin transferase (5.1%)" "GO:0007155 (9.1%) GO:0030198 (9%) GO:0071307 (8.9%)" "GO:0031012 (9.1%) GO:0005615 (9%) GO:0005794 (8.7%)" "GO:0050839 (9%) GO:0008201 (8.9%) GO:0009044 (5.5%)" "cell adhesion (9.1%) extracellular matrix organization (9%) cellular response to vitamin K (8.9%)" "extracellular matrix (9.1%) extracellular space (9%) Golgi apparatus (8.7%)" "cell adhesion molecule binding (9%) heparin binding (8.9%) xylan 1,4-beta-xylosidase activity (5.5%)" "IPR000782 (8.8%) IPR036378 (8.8%) IPR050904 (8.8%)" "FAS1 domain (8.8%) FAS1 domain superfamily (8.8%) Cell adhesion and biosynthesis-related protein (8.8%)" MTETEQHMEQLMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0016787 (96.8%) GO:0052689 (3.2%)" "hydrolase activity (96.8%) carboxylic ester hydrolase activity (3.2%)" "IPR002018 (21.1%) IPR019826 (19.7%) IPR029058 (19.7%)" "Carboxylesterase, type B (21.1%) Carboxylesterase type B, active site (19.7%) Alpha/Beta hydrolase fold (19.7%)" VTVFEAR root "1.3.1.1 (22.2%) 1.13.12.3 (15.9%) 2.7.11.13 (14.3%)" "dihydrouracil dehydrogenase (NAD(+)) (22.2%) tryptophan 2-monooxygenase (15.9%) protein kinase C (14.3%)" "GO:0006537 (4.1%) GO:0006338 (2.3%) GO:0036503 (1.6%)" "GO:0005737 (9.2%) GO:0005886 (2.3%) GO:0005634 (1.8%)" "GO:0016491 (18.1%) GO:0051536 (11.2%) GO:0016639 (4.1%)" "glutamate biosynthetic process (4.1%) chromatin remodeling (2.3%) ERAD pathway (1.6%)" "cytoplasm (9.2%) plasma membrane (2.3%) nucleus (1.8%)" "oxidoreductase activity (18.1%) iron-sulfur cluster binding (11.2%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (4.1%)" "IPR036188 (19.9%) IPR023753 (7.9%) IPR009051 (7.6%)" "FAD/NAD(P)-binding domain superfamily (19.9%) FAD/NAD(P)-binding domain (7.9%) Alpha-helical ferredoxin (7.6%)" FTQAGSEVSALLGR root "7.1.2.2 (99.2%) 3.6.3.14 (0.8%) 7.2.2.1 (0%)" "H(+)-transporting two-sector ATPase (99.2%) Transferred entry: 7.1.2.2 (0.8%) Na(+)-transporting two-sector ATPase (0%)" "GO:0042776 (8.4%) GO:0001525 (0.2%) GO:0043536 (0.2%)" "GO:0045259 (20.7%) GO:0005886 (11.7%) GO:0005743 (4.6%)" "GO:0005524 (20.7%) GO:0046933 (20.7%) GO:0016787 (2.9%)" "proton motive force-driven mitochondrial ATP synthesis (8.4%) angiogenesis (0.2%) positive regulation of blood vessel endothelial cell migration (0.2%)" "proton-transporting ATP synthase complex (20.7%) plasma membrane (11.7%) mitochondrial inner membrane (4.6%)" "ATP binding (20.7%) proton-transporting ATP synthase activity, rotational mechanism (20.7%) hydrolase activity (2.9%)" "IPR000194 (10.3%) IPR027417 (10.2%) IPR050053 (10.2%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.3%) P-loop containing nucleoside triphosphate hydrolase (10.2%) ATPase alpha/beta chains (10.2%)" VLFLPDGNDPDSFAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.101 (100%) DNA primase DnaG (100%) GO:0006269 (14.3%) "GO:0000428 (14.3%) GO:0005737 (14.3%) GO:1990077 (14.3%)" "GO:0003677 (14.3%) GO:0003899 (14.3%) GO:0008270 (14.3%)" DNA replication, synthesis of primer (14.3%) "DNA-directed RNA polymerase complex (14.3%) cytoplasm (14.3%) primosome complex (14.3%)" "DNA binding (14.3%) DNA-directed RNA polymerase activity (14.3%) zinc ion binding (14.3%)" "IPR002694 (10.1%) IPR006171 (10.1%) IPR006295 (10.1%)" "Zinc finger, CHC2-type (10.1%) TOPRIM domain (10.1%) DNA primase, DnaG (10.1%)" VDNSAEYYQAAEFYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0042254 (30.8%) "GO:0005525 (30.8%) GO:0043022 (30.8%) GO:0016787 (7.7%)" ribosome biogenesis (30.8%) "GTP binding (30.8%) ribosome binding (30.8%) hydrolase activity (7.7%)" "IPR005225 (14.5%) IPR006073 (14.5%) IPR016484 (14.5%)" "Small GTP-binding domain (14.5%) GTP binding domain (14.5%) GTPase Der (14.5%)" TPELSVLEAQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044341 (33.3%) GO:0005886 (33.3%) GO:0005436 (33.3%) sodium-dependent phosphate transport (33.3%) plasma membrane (33.3%) sodium:phosphate symporter activity (33.3%) "IPR003841 (39.7%) IPR038078 (39.1%) IPR004633 (12.3%)" "Sodium-dependent phosphate transport protein (39.7%) PhoU-like domain superfamily (39.1%) Na/Pi-cotransporter II-related/YqeW-like protein (12.3%)" DLNCFTVESAMK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000911 (14.3%) IPR006519 (14.3%) IPR020783 (14.3%)" "Ribosomal protein uL11 (14.3%) Large ribosomal subunit protein uL11, bacteria (14.3%) Large ribosomal subunit protein uL11, C-terminal (14.3%)" LLQQAENDAYAPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (55%) IPR024930 (45%)" "Chaperone protein Skp (55%) Skp domain superfamily (45%)" MLLATGFLR Pseudomonadati Bacteria Pseudomonadati 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17%) GO:0009090 (17%) GO:0009088 (12.1%)" GO:0005829 (17%) "GO:0004072 (17%) GO:0005524 (17%) GO:0009055 (1.4%)" "lysine biosynthetic process via diaminopimelate (17%) homoserine biosynthetic process (17%) threonine biosynthetic process (12.1%)" cytosol (17%) "aspartate kinase activity (17%) ATP binding (17%) electron transfer activity (1.4%)" "IPR045865 (13.7%) IPR054352 (13.7%) IPR001048 (13.5%)" "ACT-like domain (13.7%) Aspartokinase, ACT domain (13.7%) Aspartate/glutamate/uridylate kinase (13.5%)" QLLDFYKQDPENAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" VKEAYDLLVEGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.4.2.12 (100%) phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (100%) "GO:0006007 (20%) GO:0006096 (20%)" GO:0005829 (20%) "GO:0004619 (20%) GO:0030145 (20%)" "glucose catabolic process (20%) glycolytic process (20%)" cytosol (20%) "phosphoglycerate mutase activity (20%) manganese ion binding (20%)" "IPR005995 (20.2%) IPR011258 (20.2%) IPR006124 (20%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20.2%) BPG-independent PGAM, N-terminal (20.2%) Metalloenzyme (20%)" ETENSLSLLLGDQAHSLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (49.1%) GO:0015562 (50.9%) plasma membrane (49.1%) efflux transmembrane transporter activity (50.9%) "IPR003423 (33.7%) IPR050737 (33.7%) IPR010131 (32.6%)" "Outer membrane efflux protein (33.7%) Unknown (33.7%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (32.6%)" EVLDYVDQNPGSLGVLGSNWLNDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024370 (52%) IPR050811 (48%)" "PBP domain (52%) Phosphate-binding ABC transporter substrate-binding (48%)" DYYVNDDEQTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.4%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.4%)" GDPAGWVAPVTPGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) GO:0022625 (20%) "GO:0003735 (20%) GO:0019843 (20%) GO:0000049 (19.8%)" translation (20%) cytosolic large ribosomal subunit (20%) "structural constituent of ribosome (20%) rRNA binding (20%) tRNA binding (19.8%)" "IPR000114 (20%) IPR016180 (20%) IPR020798 (20%)" "Large ribosomal subunit protein uL16, bacteria (20%) Large ribosomal subunit protein uL16 domain (20%) Large ribosomal subunit protein uL16, conserved site (20%)" NLATSLEMK Pseudomonadati Bacteria Pseudomonadati 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005146 (7.9%) IPR005147 (7.9%) IPR045060 (7.9%)" "B3/B4 tRNA-binding domain (7.9%) tRNA synthetase, B5-domain (7.9%) Phenylalanine-tRNA ligase, class IIc, beta subunit (7.9%)" STLSGLLLDLPVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" QNNDLQGLQQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0050821 (33.3%) GO:0005829 (33.3%) GO:0051082 (33.3%) protein stabilization (33.3%) cytosol (33.3%) unfolded protein binding (33.3%) "IPR005632 (50%) IPR024930 (50%)" "Chaperone protein Skp (50%) Skp domain superfamily (50%)" VLLVDKDGSLTVGAPAVEGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR001787 (30%) IPR028909 (30%) IPR036164 (30%)" "Large ribosomal subunit protein bL21 (30%) Large ribosomal subunit protein bL21-like (30%) Large ribosomal subunit protein bL21-like superfamily (30%)" EFLQLLR root "3.5.4.16 (33.1%) 2.6.1.11 (11.6%) 2.7.11.1 (6.3%)" "GTP cyclohydrolase I (33.1%) acetylornithine transaminase (11.6%) non-specific serine/threonine protein kinase (6.3%)" "GO:0006729 (2%) GO:0046654 (2%) GO:0006730 (1.9%)" "GO:0005886 (5%) GO:0005737 (4.3%) GO:0016020 (3.5%)" "GO:0005524 (4.1%) GO:0008270 (3%) GO:0005525 (2.4%)" "tetrahydrobiopterin biosynthetic process (2%) tetrahydrofolate biosynthetic process (2%) one-carbon metabolic process (1.9%)" "plasma membrane (5%) cytoplasm (4.3%) membrane (3.5%)" "ATP binding (4.1%) zinc ion binding (3%) GTP binding (2.4%)" "IPR027417 (4.4%) IPR015421 (1.8%) IPR015424 (1.8%)" "P-loop containing nucleoside triphosphate hydrolase (4.4%) Pyridoxal phosphate-dependent transferase, major domain (1.8%) Pyridoxal phosphate-dependent transferase (1.8%)" RYDLGEVGR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (18.9%) GO:0006508 (0.2%) GO:0006412 (0%)" "GO:0000428 (18.8%) GO:0009507 (2.8%) GO:0009536 (2.3%)" "GO:0003677 (18.9%) GO:0003899 (18.9%) GO:0032549 (18.8%)" "DNA-templated transcription (18.9%) proteolysis (0.2%) translation (0%)" "DNA-directed RNA polymerase complex (18.8%) chloroplast (2.8%) plastid (2.3%)" "DNA binding (18.9%) DNA-directed RNA polymerase activity (18.9%) ribonucleoside binding (18.8%)" "IPR007642 (7.9%) IPR015712 (7.9%) IPR007645 (7.9%)" "RNA polymerase Rpb2, domain 2 (7.9%) DNA-directed RNA polymerase, subunit 2 (7.9%) RNA polymerase Rpb2, domain 3 (7.9%)" LELLSVGGK root 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0006457 (46.7%) GO:0072659 (3.3%)" GO:0019867 (3.3%) GO:0003755 (46.7%) "protein folding (46.7%) protein localization to plasma membrane (3.3%)" outer membrane (3.3%) peptidyl-prolyl cis-trans isomerase activity (46.7%) "IPR000774 (21.5%) IPR001179 (21.5%) IPR036944 (21.5%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (21.5%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (21.5%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (21.5%)" SKDLVNWETVNYLFPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.7%) IPR006584 (12.7%) IPR006710 (12.7%)" "Carbohydrate binding module family 6 (12.7%) Cellulose binding, type IV (12.7%) Glycoside hydrolase, family 43 (12.7%)" GEYNPVTTNDTEVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR006665 (34.1%) IPR050330 (34.1%) IPR036737 (31.7%)" "OmpA-like domain (34.1%) Bacterial Outer Membrane Structural/Functional (34.1%) OmpA-like domain superfamily (31.7%)" ESEPDLYNALKR Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.8%) GO:0005829 (17.7%) "GO:0004612 (17.8%) GO:0005524 (17.8%) GO:0046872 (16.9%)" gluconeogenesis (17.8%) cytosol (17.7%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.8%) ATP binding (17.8%) metal ion binding (16.9%)" "IPR001272 (25.4%) IPR013035 (25.3%) IPR015994 (24.8%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.4%) Phosphoenolpyruvate carboxykinase, C-terminal (25.3%) Phosphoenolpyruvate carboxykinase (ATP), conserved site (24.8%)" KDDTVLVLAGADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR003256 (14.3%) IPR005824 (14.3%) IPR005825 (14.3%)" "Large ribosomal subunit protein uL24 (14.3%) KOW (14.3%) Large ribosomal subunit protein uL24, conserved site (14.3%)" LDKYAAAYAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0070181 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) small ribosomal subunit rRNA binding (16.7%)" "IPR000529 (25%) IPR014717 (25%) IPR020814 (25%)" "Small ribosomal subunit protein bS6 (25%) Translation elongation factor EF1B/small ribosomal subunit protein bS6 (25%) Small ribosomal subunit protein bS6, plastid/chloroplast (25%)" LLLTGPNANQMR Bacteria Bacteria 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (48.8%) GO:0005975 (1.2%)" "GO:0008422 (48.8%) GO:0004553 (1.2%)" "glucan catabolic process (48.8%) carbohydrate metabolic process (1.2%)" "beta-glucosidase activity (48.8%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.2%)" "IPR002772 (12.9%) IPR001764 (12.6%) IPR026891 (12.6%)" "Glycoside hydrolase family 3 C-terminal domain (12.9%) Glycoside hydrolase, family 3, N-terminal (12.6%) Fibronectin type III-like domain (12.6%)" TLTVGSDLKPLVETTLPYDVVEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0030246 (49.3%) GO:0016798 (47.8%) GO:0016787 (3%)" "carbohydrate binding (49.3%) hydrolase activity, acting on glycosyl bonds (47.8%) hydrolase activity (3%)" "IPR019563 (12.8%) IPR029486 (12.8%) IPR052720 (12.8%)" "Glycosyl-hydrolase 97, catalytic domain (12.8%) Glycosyl-hydrolase 97, N-terminal domain (12.8%) Glycosyl Hydrolase Family 97 (12.8%)" TGFDCNGKTEEELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.8%) GO:0005829 (16.8%) "GO:0000049 (16.8%) GO:0004824 (16.8%) GO:0005524 (16.8%)" lysyl-tRNA aminoacylation (16.8%) cytosol (16.8%) "tRNA binding (16.8%) lysine-tRNA ligase activity (16.8%) ATP binding (16.8%)" "IPR004364 (12.8%) IPR006195 (12.8%) IPR002313 (12.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (12.8%) Aminoacyl-tRNA synthetase, class II (12.8%) Lysine-tRNA ligase, class II (12.2%)" EDFYTTDLMTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.182 (100%) 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase (100%) GO:0005829 (33.3%) "GO:0003723 (33.3%) GO:0000179 (20.8%) GO:0052908 (12.5%)" cytosol (33.3%) "RNA binding (33.3%) rRNA (adenine-N6,N6-)-dimethyltransferase activity (20.8%) 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity (12.5%)" "IPR001737 (17%) IPR011530 (17%) IPR020596 (17%)" "Ribosomal RNA adenine methyltransferase KsgA/Erm (17%) Ribosomal RNA adenine dimethylase (17%) Ribosomal RNA adenine methylase transferase, conserved site (17%)" LVAESGVGTLAAGVAK Pseudomonadati Bacteria Pseudomonadati 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (18.9%)" GO:0016020 (0.1%) "GO:0051538 (19.5%) GO:0046872 (19.5%) GO:0015930 (9.9%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (18.9%)" membrane (0.1%) "3 iron, 4 sulfur cluster binding (19.5%) metal ion binding (19.5%) glutamate synthase activity (9.9%)" "IPR002932 (12.8%) IPR013785 (12.7%) IPR002489 (12.6%)" "Glutamate synthase domain (12.8%) Aldolase-type TIM barrel (12.7%) Glutamate synthase, alpha subunit, C-terminal (12.6%)" LLNEGTATVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016740 (100%) transferase activity (100%) IPR029044 (100%) Nucleotide-diphospho-sugar transferases (100%) FGMEFVELKDAFTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004815 (20%) GO:0005524 (20%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) aspartate-tRNA ligase activity (20%) ATP binding (20%)" "IPR004364 (9.2%) IPR004365 (9.2%) IPR004524 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (9.2%) Aspartate-tRNA ligase, type 1 (9.2%)" ASFGYLDHNTLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.7%) IPR023997 (14.7%) IPR039426 (14.7%)" "TonB-dependent receptor, plug domain (14.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%) TonB-dependent receptor-like (14.7%)" QFVDFFGVGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (41.8%) "GO:0004475 (41.8%) GO:0005525 (12.7%) GO:0016853 (3.6%)" GDP-mannose biosynthetic process (41.8%) "mannose-1-phosphate guanylyltransferase (GTP) activity (41.8%) GTP binding (12.7%) isomerase activity (3.6%)" "IPR005835 (25.6%) IPR051161 (25.6%) IPR029044 (24.4%)" "Nucleotidyl transferase domain (25.6%) Mannose-6-phosphate isomerase type 2 (25.6%) Nucleotide-diphospho-sugar transferases (24.4%)" KYEEALTAPGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) SGSLSLSNPDPALR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (33.3%) IPR036237 (33.3%) IPR050337 (33.3%)" "Rhamnose isomerase (33.3%) Xylose isomerase-like superfamily (33.3%) L-rhamnose isomerase (33.3%)" FEAAAGAEKAPDLDL Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" FLNEANLLDLSNLFEDSKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006261 (50%) GO:0016740 (50%) DNA-templated DNA replication (50%) transferase activity (50%) "IPR050238 (51.4%) IPR027417 (48.6%)" "DNA Replication and Repair Clamp Loader Complex (51.4%) P-loop containing nucleoside triphosphate hydrolase (48.6%)" AVLPNPQDLGENYDGETSLGCR Pseudomonadati Bacteria Pseudomonadati "1.5.1.7 (86.7%) 1.-.-.- (13.3%)" "saccharopine dehydrogenase (NAD(+), L-lysine-forming) (86.7%) Oxidoreductases (13.3%)" "GO:0004754 (86.7%) GO:0016491 (13.3%)" "saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (86.7%) oxidoreductase activity (13.3%)" "IPR032095 (33.7%) IPR005097 (32.5%) IPR036291 (32.5%)" "Saccharopine dehydrogenase-like, C-terminal (33.7%) Saccharopine dehydrogenase, NADP binding domain (32.5%) NAD(P)-binding domain superfamily (32.5%)" FKQVVEEFENEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003899 (16.7%) GO:0046983 (16.7%) GO:0003677 (16.5%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%) DNA binding (16.5%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR036603 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) RNA polymerase, RBP11-like subunit (16.7%)" GWNVGGGDAESHYEAGVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (38.1%) IPR011990 (33.3%) IPR024302 (28.6%)" "SusD-like 2 (38.1%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like (28.6%)" EALGLEGR root "1.1.1.49 (62.5%) 1.1.1.363 (4.2%) 1.1.5.4 (4.2%)" "glucose-6-phosphate dehydrogenase (NADP(+)) (62.5%) glucose-6-phosphate dehydrogenase [NAD(P)(+)] (4.2%) malate dehydrogenase (quinone) (4.2%)" "GO:0006006 (8.4%) GO:0009051 (8.4%) GO:0006508 (1%)" "GO:0016020 (12.3%) GO:0005829 (8.7%) GO:0005737 (4.8%)" "GO:0004345 (8.4%) GO:0050661 (8.4%) GO:0046872 (3.9%)" "glucose metabolic process (8.4%) pentose-phosphate shunt, oxidative branch (8.4%) proteolysis (1%)" "membrane (12.3%) cytosol (8.7%) cytoplasm (4.8%)" "glucose-6-phosphate dehydrogenase activity (8.4%) NADP binding (8.4%) metal ion binding (3.9%)" "IPR003672 (9.2%) IPR036291 (6.9%) IPR001282 (6.6%)" "CobN/magnesium chelatase (9.2%) NAD(P)-binding domain superfamily (6.9%) Glucose-6-phosphate dehydrogenase (6.6%)" LLEFLAVR root "3.4.21.53 (97.7%) 3.4.21.- (2%) 2.7.13.3 (0.1%)" "endopeptidase La (97.7%) Serine endopeptidases (2%) histidine kinase (0.1%)" "GO:0006515 (11.3%) GO:0034605 (10.9%) GO:0006508 (1.1%)" "GO:0005737 (11.7%) GO:0005886 (0.3%) GO:0005759 (0.2%)" "GO:0005524 (12.5%) GO:0016887 (12.5%) GO:0004176 (12.4%)" "protein quality control for misfolded or incompletely synthesized proteins (11.3%) cellular response to heat (10.9%) proteolysis (1.1%)" "cytoplasm (11.7%) plasma membrane (0.3%) mitochondrial matrix (0.2%)" "ATP binding (12.5%) ATP hydrolysis activity (12.5%) ATP-dependent peptidase activity (12.4%)" "IPR027417 (7.3%) IPR003959 (7.3%) IPR027065 (7.3%)" "P-loop containing nucleoside triphosphate hydrolase (7.3%) ATPase, AAA-type, core (7.3%) Lon protease (7.3%)" GQDVVDKNFGAVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (13.9%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (13.9%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" LTLMSESLR root "1.3.5.1 (98.5%) 1.3.5.4 (1.4%) 1.3.99.1 (0.1%)" "succinate dehydrogenase (98.5%) Transferred entry: 1.3.5.1 (1.4%) Deleted entry (0.1%)" "GO:0009061 (18.7%) GO:0006108 (0%) GO:0006313 (0%)" "GO:0005886 (18.7%) GO:0005829 (0%) GO:0009317 (0%)" "GO:0009055 (18.7%) GO:0050660 (18.7%) GO:0000104 (14.8%)" "anaerobic respiration (18.7%) malate metabolic process (0%) DNA transposition (0%)" "plasma membrane (18.7%) cytosol (0%) acetyl-CoA carboxylase complex (0%)" "electron transfer activity (18.7%) flavin adenine dinucleotide binding (18.7%) succinate dehydrogenase activity (14.8%)" "IPR003953 (14.3%) IPR030664 (14.3%) IPR036188 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.3%) FAD/NAD(P)-binding domain superfamily (14.3%)" TLGNDAECFCLTCPLLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.9%) GO:0005829 (16.9%) "GO:0003723 (16.9%) GO:0004831 (16.9%) GO:0005524 (16.9%)" tyrosyl-tRNA aminoacylation (16.9%) cytosol (16.9%) "RNA binding (16.9%) tyrosine-tRNA ligase activity (16.9%) ATP binding (16.9%)" "IPR002305 (12.7%) IPR002307 (12.7%) IPR014729 (12.7%)" "Aminoacyl-tRNA synthetase, class Ic (12.7%) Tyrosine-tRNA ligase (12.7%) Rossmann-like alpha/beta/alpha sandwich fold (12.7%)" QLPMFDFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.5%) GO:0005829 (17.5%) "GO:0004612 (17.5%) GO:0005524 (17.5%) GO:0046872 (17.5%)" gluconeogenesis (17.5%) cytosol (17.5%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.5%) ATP binding (17.5%) metal ion binding (17.5%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" DVLYLNAENAGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019707 (52.4%) IPR036388 (47.6%)" "MJ1608-like (52.4%) Winged helix-like DNA-binding domain superfamily (47.6%)" GVVMNPVDHPMGGGEGR root GO:0002181 (19.9%) "GO:0015934 (19.9%) GO:0005840 (0.1%) GO:1990904 (0.1%)" "GO:0003735 (20%) GO:0016740 (19.9%) GO:0019843 (18.6%)" cytoplasmic translation (19.9%) "large ribosomal subunit (19.9%) ribosome (0.1%) ribonucleoprotein complex (0.1%)" "structural constituent of ribosome (20%) transferase activity (19.9%) rRNA binding (18.6%)" "IPR002171 (11.1%) IPR008991 (11.1%) IPR014726 (11.1%)" "Large ribosomal subunit protein uL2 (11.1%) Translation protein SH3-like domain superfamily (11.1%) Large ribosomal subunit protein uL2, domain 3 (11.1%)" LDPSLYLYGEGWSAGSCAYPTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (50.6%) "GO:0016798 (33.3%) GO:0051060 (16%)" carbohydrate metabolic process (50.6%) "hydrolase activity, acting on glycosyl bonds (33.3%) pullulanase activity (16%)" "IPR006047 (14.7%) IPR011840 (14.4%) IPR017853 (14.4%)" "Glycosyl hydrolase family 13, catalytic domain (14.7%) Pullulanase, type I (14.4%) Glycoside hydrolase superfamily (14.4%)" AADLVLSR root "2.4.1.227 (92.8%) 3.4.14.10 (4.7%) 1.3.1.1 (0.6%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (92.8%) tripeptidyl-peptidase II (4.7%) dihydrouracil dehydrogenase (NAD(+)) (0.6%)" "GO:0005975 (11.2%) GO:0030259 (11.2%) GO:0008360 (10.4%)" "GO:0005886 (10.5%) GO:0005829 (0.9%) GO:0005634 (0.5%)" "GO:0050511 (10.4%) GO:0051991 (5.6%) GO:0016758 (1%)" "carbohydrate metabolic process (11.2%) obsolete lipid glycosylation (11.2%) regulation of cell shape (10.4%)" "plasma membrane (10.5%) cytosol (0.9%) nucleus (0.5%)" "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (10.4%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (5.6%) hexosyltransferase activity (1%)" "IPR007235 (23.6%) IPR004276 (23.2%) IPR006009 (21.6%)" "Glycosyl transferase, family 28, C-terminal (23.6%) Glycosyltransferase family 28, N-terminal domain (23.2%) N-acetylglucosaminyltransferase, MurG (21.6%)" GTDAVGQYPEPYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (25%) GO:0005576 (25%) "GO:0033939 (25%) GO:0046559 (25%)" xylan catabolic process (25%) extracellular region (25%) "xylan alpha-1,2-glucuronosidase activity (25%) alpha-glucuronidase activity (25%)" "IPR011099 (20.9%) IPR011100 (20.3%) IPR017853 (19.8%)" "Glycosyl hydrolase family 67, C-terminal (20.9%) Glycosyl hydrolase family 67, catalytic domain (20.3%) Glycoside hydrolase superfamily (19.8%)" APVVLNLLPLDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" QALQNLSNVLFEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.8%) GO:0009090 (17.8%) GO:0009088 (11%)" GO:0005829 (17.8%) "GO:0004072 (17.8%) GO:0005524 (17.8%)" "lysine biosynthetic process via diaminopimelate (17.8%) homoserine biosynthetic process (17.8%) threonine biosynthetic process (11%)" cytosol (17.8%) "aspartate kinase activity (17.8%) ATP binding (17.8%)" "IPR001048 (14.3%) IPR001341 (14.3%) IPR005260 (14.3%)" "Aspartate/glutamate/uridylate kinase (14.3%) Aspartate kinase (14.3%) Aspartate kinase, monofunctional class (14.3%)" GFLDLVWLPQSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.5%) "GO:0004556 (32.3%) GO:0043169 (32.3%)" carbohydrate metabolic process (35.5%) "alpha-amylase activity (32.3%) cation binding (32.3%)" "IPR006047 (35.5%) IPR006046 (32.3%) IPR017853 (32.3%)" "Glycosyl hydrolase family 13, catalytic domain (35.5%) Alpha amylase (32.3%) Glycoside hydrolase superfamily (32.3%)" YVTLKPGDVLSVTVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR026444 (100%) Secretion system, C-terminal sorting domain (100%) SLLGEGGTLKPNFWR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.2%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.2%)" "IPR004199 (7.3%) IPR006102 (7.3%) IPR006103 (7.3%)" "Beta galactosidase small chain/ domain 5 (7.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.3%) Glycoside hydrolase family 2, catalytic domain (7.3%)" DMLESGVLK root 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0006004 (1.8%) GO:0042776 (0.6%)" "GO:0045259 (20.5%) GO:0005886 (19.9%) GO:0005634 (1.8%)" "GO:0005524 (20.5%) GO:0046933 (20.5%) GO:0016787 (8.8%)" "fucose metabolic process (1.8%) proton motive force-driven mitochondrial ATP synthesis (0.6%)" "proton-transporting ATP synthase complex (20.5%) plasma membrane (19.9%) nucleus (1.8%)" "ATP binding (20.5%) proton-transporting ATP synthase activity, rotational mechanism (20.5%) hydrolase activity (8.8%)" "IPR000194 (10%) IPR027417 (10%) IPR050053 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) P-loop containing nucleoside triphosphate hydrolase (10%) ATPase alpha/beta chains (10%)" FKGSAGQSFGAFLVK Pseudomonadati Bacteria Pseudomonadati 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20%) GO:0019676 (20%)" "GO:0046872 (20%) GO:0051538 (20%) GO:0015930 (14.8%)" "glutamate biosynthetic process (20%) ammonia assimilation cycle (20%)" "metal ion binding (20%) 3 iron, 4 sulfur cluster binding (20%) glutamate synthase activity (14.8%)" "IPR002489 (12.7%) IPR002932 (12.7%) IPR006982 (12.7%)" "Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%) Glutamate synthase, central-N (12.7%)" VWAVLTVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TAGVFQNMAEVQAYVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" STFCSYVLGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) GO:0005886 (23.2%) "GO:0005524 (26.8%) GO:0016887 (26.8%) GO:0022857 (23.2%)" plasma membrane (23.2%) "ATP binding (26.8%) ATP hydrolysis activity (26.8%) transmembrane transporter activity (23.2%)" "IPR003439 (31.9%) IPR027417 (30.9%) IPR015854 (27.7%)" "ABC transporter-like, ATP-binding domain (31.9%) P-loop containing nucleoside triphosphate hydrolase (30.9%) ABC transporter, lipoprotein release, LolD-like (27.7%)" LSDNEQLETER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005525 (33.3%) GO:0035091 (33.3%) GO:0070300 (33.3%)" "GTP binding (33.3%) phosphatidylinositol binding (33.3%) phosphatidic acid binding (33.3%)" "IPR038727 (25.9%) IPR053227 (25.9%) IPR027417 (24.1%)" "NadR/Ttd14, AAA domain (25.9%) TRPL channel trafficking regulator (25.9%) P-loop containing nucleoside triphosphate hydrolase (24.1%)" EAHEAMALAMNALGAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20.2%) GO:0019676 (19.7%)" "GO:0046872 (19.7%) GO:0051538 (19.7%) GO:0015930 (14.1%)" "glutamate biosynthetic process (20.2%) ammonia assimilation cycle (19.7%)" "metal ion binding (19.7%) 3 iron, 4 sulfur cluster binding (19.7%) glutamate synthase activity (14.1%)" "IPR002932 (12.9%) IPR002489 (12.6%) IPR006982 (12.6%)" "Glutamate synthase domain (12.9%) Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase, central-N (12.6%)" KGPYLNVSLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000028 (16.7%) GO:0006412 (16.7%)" "GO:0005737 (16.7%) GO:0015935 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" "ribosomal small subunit assembly (16.7%) translation (16.7%)" "cytoplasm (16.7%) small ribosomal subunit (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002222 (25%) IPR005732 (25%) IPR020934 (25%)" "Small ribosomal subunit protein uS19 (25%) Small ribosomal subunit protein uS19, bacteria (25%) Small ribosomal subunit protein uS19, conserved site (25%)" VSEETENEEDDLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.3%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.3%)" "IPR000241 (17.1%) IPR002052 (17.1%) IPR004114 (16.6%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.1%) DNA methylase, N-6 adenine-specific, conserved site (17.1%) THUMP domain (16.6%)" SGALPWLGEGMYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006102 (9.3%) IPR006103 (9.3%) IPR006104 (9.3%)" "Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.3%) Glycoside hydrolase family 2, catalytic domain (9.3%) Glycosyl hydrolases family 2, sugar binding domain (9.3%)" LLENNLLPDANLFTSQYVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR024214 (100%) Protein of unknown function DUF3843 (100%) TFSTENVSGLLGTGGTMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" GO:0005945 (9.1%) "GO:0003872 (9.1%) GO:0005524 (9.1%) GO:0016208 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" 6-phosphofructokinase complex (9.1%) "6-phosphofructokinase activity (9.1%) ATP binding (9.1%) AMP binding (9.1%)" "IPR000023 (16.7%) IPR012003 (16.7%) IPR012828 (16.7%)" "Phosphofructokinase domain (16.7%) ATP-dependent 6-phosphofructokinase, prokaryotic-type (16.7%) ATP-dependent 6-phosphofructokinase, prokaryotic (16.7%)" SNTETLSFDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032184 (33.3%) IPR033429 (33.3%) IPR033430 (33.3%)" "Domain of unknown function DUF5016 (33.3%) Domain of unknown function DUF5125 (33.3%) Domain of unknown function DUF5121 (33.3%)" TGKPLEGAYADLNNDGELNESDLYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR018247 (11.9%) IPR039426 (11.9%) IPR000531 (11.2%)" "EF-Hand 1, calcium-binding site (11.9%) TonB-dependent receptor-like (11.9%) TonB-dependent receptor-like, beta-barrel (11.2%)" SAVCFEAQKFPDTPNHTYFPSCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20%) GO:0033499 (20%)" GO:0005737 (20%) "GO:0004034 (20%) GO:0030246 (20%)" "glucose metabolic process (20%) galactose catabolic process via UDP-galactose, Leloir pathway (20%)" cytoplasm (20%) "aldose 1-epimerase activity (20%) carbohydrate binding (20%)" "IPR008183 (20%) IPR011013 (20%) IPR014718 (20%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (20%) Galactose mutarotase-like domain superfamily (20%) Glycoside hydrolase-type carbohydrate-binding (20%)" DTAEYLDTVMSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006605 (24.5%) GO:0043952 (24.5%) GO:0065002 (24.5%)" "GO:0005886 (24.5%) GO:0016020 (1%)" "protein targeting (24.5%) protein transport by the Sec complex (24.5%) intracellular protein transmembrane transport (24.5%)" "plasma membrane (24.5%) membrane (1%)" "IPR002208 (25.5%) IPR023201 (25.5%) IPR026593 (24.5%)" "SecY/SEC61-alpha family (25.5%) SecY domain superfamily (25.5%) Protein translocase subunit SecY (24.5%)" YPFTLSR root "3.5.1.- (27.3%) 5.1.1.- (27.3%) 2.1.1.37 (9.1%)" "In linear amides (27.3%) Acting on amino acids and derivatives (27.3%) DNA (cytosine-5-)-methyltransferase (9.1%)" "GO:0009063 (4.6%) GO:0000002 (3.7%) GO:0006397 (3.7%)" "GO:0005743 (3.7%) GO:0016020 (1.8%) GO:0005634 (0.9%)" "GO:0016811 (15.6%) GO:0016855 (6.4%) GO:0005524 (5.5%)" "amino acid catabolic process (4.6%) obsolete mitochondrial genome maintenance (3.7%) mRNA processing (3.7%)" "mitochondrial inner membrane (3.7%) membrane (1.8%) nucleus (0.9%)" "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (15.6%) racemase and epimerase activity, acting on amino acids and derivatives (6.4%) ATP binding (5.5%)" "IPR045741 (22.1%) IPR047799 (21.9%) IPR003737 (4.1%)" "Type IX secretion system protein PorV (22.1%) Type IX secretion system, outer membrane channel protein PorV (21.9%) N-acetylglucosaminyl phosphatidylinositol deacetylase-related (4.1%)" LTADYFEK root 1.14.11.27 (100%) [histone H3]-dimethyl-L-lysine(36) demethylase (100%) "GO:0006605 (13.3%) GO:0006886 (13.3%) GO:0016192 (13.3%)" "GO:0005802 (13.3%) GO:0030131 (13.3%) GO:0005829 (3.4%)" "GO:0030276 (13.3%) GO:0000981 (0.4%) GO:0003700 (0.4%)" "protein targeting (13.3%) intracellular protein transport (13.3%) vesicle-mediated transport (13.3%)" "trans-Golgi network (13.3%) clathrin adaptor complex (13.3%) cytosol (3.4%)" "clathrin binding (13.3%) DNA-binding transcription factor activity, RNA polymerase II-specific (0.4%) DNA-binding transcription factor activity (0.4%)" "IPR002553 (11.3%) IPR011989 (11.3%) IPR012295 (11.3%)" "Clathrin/coatomer adaptor, adaptin-like, N-terminal (11.3%) Armadillo-like helical (11.3%) TBP domain superfamily (11.3%)" ELEGAGNELVLLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (48.4%) GO:0033711 (1.6%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (48.4%) 4-phosphoerythronate dehydrogenase activity (1.6%)" "IPR006139 (29.8%) IPR006140 (29.8%) IPR036291 (29.8%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (29.8%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (29.8%) NAD(P)-binding domain superfamily (29.8%)" HTLGAMAGMSFTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" FTGNVYAELEPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" RNDEVTPWLEAFVNAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.5%) GO:0006164 (0.6%)" GO:0005737 (20.1%) "GO:0004642 (20.1%) GO:0005524 (19.8%) GO:0046872 (19.8%)" "'de novo' IMP biosynthetic process (19.5%) purine nucleotide biosynthetic process (0.6%)" cytoplasm (20.1%) "phosphoribosylformylglycinamidine synthase activity (20.1%) ATP binding (19.8%) metal ion binding (19.8%)" "IPR010918 (11.2%) IPR029062 (11.2%) IPR040707 (11.2%)" "PurM-like, C-terminal domain (11.2%) Class I glutamine amidotransferase-like (11.2%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.2%)" ANDNGNCLHGGGATGWLNQVYDLTEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20.3%) GO:0033499 (20.3%)" GO:0005737 (20.3%) "GO:0004034 (20.3%) GO:0030246 (18.8%)" "glucose metabolic process (20.3%) galactose catabolic process via UDP-galactose, Leloir pathway (20.3%)" cytoplasm (20.3%) "aldose 1-epimerase activity (20.3%) carbohydrate binding (18.8%)" "IPR008183 (17.3%) IPR018052 (17.3%) IPR047215 (17.3%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.3%) Aldose 1-epimerase, conserved site (17.3%) Galactose mutarotase-like (17.3%)" VLDVLDLESPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (51.3%) 6.3.4.16 (48.7%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (51.3%) carbamoyl-phosphate synthase (ammonia) (48.7%)" "GO:0006221 (14%) GO:0006526 (14%) GO:0006541 (14%)" GO:0005737 (14%) "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (14%)" "pyrimidine nucleotide biosynthetic process (14%) L-arginine biosynthetic process (14%) glutamine metabolic process (14%)" cytoplasm (14%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (14%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" VGDLVLAGTSWGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (25.2%) "GO:0003743 (25.2%) GO:0005525 (25.2%) GO:0003924 (24.4%)" cytoplasm (25.2%) "translation initiation factor activity (25.2%) GTP binding (25.2%) GTPase activity (24.4%)" "IPR015760 (8.6%) IPR023115 (8.6%) IPR044145 (8.6%)" "Translation initiation factor IF- 2 (8.6%) Translation initiation factor IF- 2, domain 3 (8.6%) Translation initiation factor IF-2, domain II (8.6%)" LVYTTDGTDPTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (34.8%) "GO:0004556 (32.6%) GO:0043169 (32.6%)" carbohydrate metabolic process (34.8%) "alpha-amylase activity (32.6%) cation binding (32.6%)" "IPR006047 (34.8%) IPR006046 (32.6%) IPR017853 (32.6%)" "Glycosyl hydrolase family 13, catalytic domain (34.8%) Alpha amylase (32.6%) Glycoside hydrolase superfamily (32.6%)" VTADNNQLGELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TYLNMYNFGFAQSHSLPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) AHFYSNLNYYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" LAATEASLAAAQEQLATAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (34.6%) IPR050330 (34.6%) IPR036737 (30.8%)" "OmpA-like domain (34.6%) Bacterial Outer Membrane Structural/Functional (34.6%) OmpA-like domain superfamily (30.8%)" DLALLVDK root "6.1.1.20 (92.9%) 3.2.1.25 (3.7%) 1.1.1.42 (0.4%)" "phenylalanine--tRNA ligase (92.9%) beta-mannosidase (3.7%) isocitrate dehydrogenase (NADP(+)) (0.4%)" "GO:0006432 (13.3%) GO:0005975 (0.6%) GO:0006516 (0.6%)" "GO:0009328 (13.3%) GO:0005737 (0.7%) GO:0016020 (0.4%)" "GO:0005524 (14%) GO:0000049 (13.6%) GO:0004826 (13.6%)" "phenylalanyl-tRNA aminoacylation (13.3%) carbohydrate metabolic process (0.6%) glycoprotein catabolic process (0.6%)" "phenylalanine-tRNA ligase complex (13.3%) cytoplasm (0.7%) membrane (0.4%)" "ATP binding (14%) tRNA binding (13.6%) phenylalanine-tRNA ligase activity (13.6%)" "IPR005121 (7.3%) IPR036690 (7.2%) IPR041616 (7.1%)" "Ferrodoxin-fold anticodon-binding domain (7.3%) Ferrodoxin-fold anticodon-binding domain superfamily (7.2%) Phenylalanyl tRNA synthetase beta chain, core domain (7.1%)" ALLMGMDSEAGYQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25.2%) "GO:0003746 (25.2%) GO:0005525 (25.2%) GO:0003924 (24.4%)" ribosome disassembly (25.2%) "translation elongation factor activity (25.2%) GTP binding (25.2%) GTPase activity (24.4%)" "IPR000640 (7.9%) IPR005517 (7.9%) IPR035649 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translation elongation factor EFG/EF2, domain IV (7.9%) EFG, domain V (7.9%)" YLLTATFR Pseudomonadati Bacteria Pseudomonadati "GO:0044718 (2.5%) GO:0006826 (1.9%) GO:0000272 (0.3%)" "GO:0009279 (91.8%) GO:0016020 (0.3%)" "GO:0015344 (2.5%) GO:0004553 (0.3%) GO:0030246 (0.3%)" "siderophore transmembrane transport (2.5%) iron ion transport (1.9%) polysaccharide catabolic process (0.3%)" "cell outer membrane (91.8%) membrane (0.3%)" "siderophore uptake transmembrane transporter activity (2.5%) hydrolase activity, hydrolyzing O-glycosyl compounds (0.3%) carbohydrate binding (0.3%)" "IPR023996 (13.3%) IPR039426 (13.3%) IPR036942 (13.2%)" "TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent receptor-like (13.3%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.2%)" LTVSSVGVK root "2.1.1.192 (94.4%) 2.1.1.- (5.6%)" "23S rRNA (adenine(2503)-C(2))-methyltransferase (94.4%) Methyltransferases (5.6%)" "GO:0030488 (12.6%) GO:0070475 (12.6%)" GO:0005737 (12.4%) "GO:0046872 (12.6%) GO:0051539 (12.6%) GO:0000049 (8.2%)" "tRNA methylation (12.6%) rRNA base methylation (12.6%)" cytoplasm (12.4%) "metal ion binding (12.6%) 4 iron, 4 sulfur cluster binding (12.6%) tRNA binding (8.2%)" "IPR007197 (17%) IPR040072 (17%) IPR027492 (16.7%)" "Radical SAM (17%) Methyltransferase (Class A) (17%) Dual-specificity RNA methyltransferase RlmN (16.7%)" ENVLCGHLLPAGTGLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.9%) "GO:0003899 (16.8%) GO:0003677 (16.7%) GO:0000287 (16.3%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.9%) "DNA-directed RNA polymerase activity (16.8%) DNA binding (16.7%) magnesium ion binding (16.3%)" "IPR007081 (9.2%) IPR000722 (9.1%) IPR006592 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.2%) RNA polymerase, alpha subunit (9.1%) RNA polymerase, N-terminal (9.1%)" WDLAVSPHLYAVTTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006811 (9.1%) "GO:0009279 (72.7%) GO:0046930 (9.1%)" GO:0015288 (9.1%) monoatomic ion transport (9.1%) "cell outer membrane (72.7%) pore complex (9.1%)" porin activity (9.1%) "IPR011250 (29.9%) IPR006664 (15%) IPR006665 (15%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (29.9%) Outer membrane protein, bacterial (15%) OmpA-like domain (15%)" QYVAFADK root "GO:0006004 (26.2%) GO:0043165 (2.4%) GO:0106004 (2.4%)" "GO:0005737 (26.2%) GO:0005634 (2.4%) GO:0005829 (2.4%)" "GO:0008736 (26.2%) GO:0015221 (2.4%) GO:0017089 (2.4%)" "fucose metabolic process (26.2%) Gram-negative-bacterium-type cell outer membrane assembly (2.4%) tRNA (guanine-N7)-methylation (2.4%)" "cytoplasm (26.2%) nucleus (2.4%) cytosol (2.4%)" "L-fucose isomerase activity (26.2%) lipopolysaccharide transmembrane transporter activity (2.4%) glycolipid transfer activity (2.4%)" "IPR015888 (37.1%) IPR009015 (36%) IPR001680 (3.4%)" "L-fucose isomerase, C-terminal (37.1%) L-fucose isomerase, N-terminal/central domain superfamily (36%) WD40 repeat (3.4%)" LLALPLMEEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.1.1.148 (100%) thymidylate synthase (FAD) (100%) "GO:0006231 (18.1%) GO:0032259 (9.7%)" "GO:0004799 (18.1%) GO:0050660 (18.1%) GO:0050797 (18.1%)" "dTMP biosynthetic process (18.1%) methylation (9.7%)" "thymidylate synthase activity (18.1%) flavin adenine dinucleotide binding (18.1%) thymidylate synthase (FAD) activity (18.1%)" "IPR003669 (54.2%) IPR036098 (45.8%)" "Thymidylate synthase ThyX (54.2%) Thymidylate synthase ThyX superfamily (45.8%)" FLCTQGAEPVEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0016301 (100%) kinase activity (100%) "IPR002173 (25.4%) IPR011611 (25.4%) IPR050306 (25.4%)" "Carbohydrate/purine kinase, PfkB, conserved site (25.4%) Carbohydrate kinase PfkB (25.4%) PfkB Carbohydrate Kinase (25.4%)" VLADLAVNNPEAFK Bacteria Bacteria "GO:0006412 (16.7%) GO:0000027 (16.4%)" "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" "translation (16.7%) ribosomal large subunit assembly (16.4%)" "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR005813 (33.3%) IPR035566 (33.3%) IPR049946 (33.3%)" "Large ribosomal subunit protein bL20 (33.3%) Ribosomal protein bL20, C-terminal (33.3%) Large ribosomal subunit protein bL20, conserved site (33.3%)" FHSTQDGLSLSSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20.2%) GO:0019676 (19.7%)" "GO:0046872 (19.7%) GO:0051538 (19.7%) GO:0015930 (14.1%)" "glutamate biosynthetic process (20.2%) ammonia assimilation cycle (19.7%)" "metal ion binding (19.7%) 3 iron, 4 sulfur cluster binding (19.7%) glutamate synthase activity (14.1%)" "IPR002932 (12.9%) IPR002489 (12.6%) IPR006982 (12.6%)" "Glutamate synthase domain (12.9%) Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase, central-N (12.6%)" GYVPADENR Bacteria Bacteria 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.6%) "GO:0000428 (16.7%) GO:0005737 (16.6%)" "GO:0003677 (16.6%) GO:0003899 (16.6%) GO:0046983 (16.6%)" DNA-templated transcription (16.6%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.6%)" "DNA binding (16.6%) DNA-directed RNA polymerase activity (16.6%) protein dimerization activity (16.6%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR011773 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) DNA-directed RNA polymerase, alpha subunit (16.7%)" RLPGAEVSDDGTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041700 (81.4%) IPR008969 (18.6%)" "Outer membrane protein beta-barrel domain 3 (81.4%) Carboxypeptidase-like, regulatory domain superfamily (18.6%)" SDVTGALAHLDSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.6%) IPR023996 (13.6%) IPR023997 (13.6%)" "TonB-dependent receptor, plug domain (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.6%)" HDYFSASSQHATTGR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (17.1%) IPR039426 (17.1%) IPR012910 (16.7%)" "TonB-dependent receptor-like, beta-barrel (17.1%) TonB-dependent receptor-like (17.1%) TonB-dependent receptor, plug domain (16.7%)" LNSGGGDAYASEQLWR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.4.-.- (50%) 3.4.21.- (50%)" "Acting on peptide bonds (peptidases) (50%) Serine endopeptidases (50%)" GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.9%) IPR004634 (16.9%) IPR004635 (16.9%)" "Peptidase S49 (16.9%) Peptidase S49, protease IV (16.9%) Peptidase S49, SppA (16.9%)" DTVWWTTDEYK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.2%) GO:0005829 (17.2%) "GO:0004612 (17.2%) GO:0005524 (17.2%) GO:0046872 (16.7%)" gluconeogenesis (17.2%) cytosol (17.2%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.2%) ATP binding (17.2%) metal ion binding (16.7%)" "IPR001272 (25.3%) IPR008210 (25.3%) IPR013035 (24.7%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.3%) Phosphoenolpyruvate carboxykinase, N-terminal (25.3%) Phosphoenolpyruvate carboxykinase, C-terminal (24.7%)" DDPSVLGVLLSGSPYSVHDPEAFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (33.1%) "GO:0003921 (33.1%) GO:0005524 (33.1%) GO:0016740 (0.7%)" cytosol (33.1%) "GMP synthase activity (33.1%) ATP binding (33.1%) transferase activity (0.7%)" "IPR004739 (12.8%) IPR017926 (12.8%) IPR001674 (12.5%)" "GMP synthase, glutamine amidotransferase (12.8%) Glutamine amidotransferase (12.8%) GMP synthase, C-terminal (12.5%)" GEYNTLGNMGTAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025631 (100%) Putative porin-10 (100%) VSLTSVLK root "6.1.1.14 (91.7%) 3.4.21.89 (4.2%) 6.1.1.19 (4.2%)" "glycine--tRNA ligase (91.7%) signal peptidase I (4.2%) arginine--tRNA ligase (4.2%)" "GO:0006426 (8.7%) GO:0015966 (8.7%) GO:0015920 (3.1%)" "GO:0005737 (9.6%) GO:0070062 (8.7%) GO:1990742 (8.7%)" "GO:0005524 (9.2%) GO:0004081 (8.7%) GO:0004820 (8.7%)" "glycyl-tRNA aminoacylation (8.7%) diadenosine tetraphosphate biosynthetic process (8.7%) lipopolysaccharide transport (3.1%)" "cytoplasm (9.6%) extracellular exosome (8.7%) microvesicle (8.7%)" "ATP binding (9.2%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (8.7%) glycine-tRNA ligase activity (8.7%)" "IPR040214 (23.1%) IPR056522 (21.8%) IPR036427 (19.7%)" "Uncharacterized bromodomain-containing protein 10 (23.1%) Uncharacterized bromodomain-containing protein 10, helical domain (21.8%) Bromodomain-like superfamily (19.7%)" VGNMPLYK Pseudomonadati Bacteria Pseudomonadati GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (80.6%) IPR011250 (11.1%) IPR010263 (5.6%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (80.6%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (11.1%) Type VI secretion system TssK (5.6%)" EYVVQDGDLMHFR Bacteria Bacteria GO:0005737 (20.2%) "GO:0005524 (20.2%) GO:0016887 (20.2%) GO:0005525 (19.9%)" cytoplasm (20.2%) "ATP binding (20.2%) ATP hydrolysis activity (20.2%) GTP binding (19.9%)" "IPR004095 (10.1%) IPR013029 (10.1%) IPR012675 (10%)" "TGS (10.1%) YchF, C-terminal domain (10.1%) Beta-grasp domain superfamily (10%)" WDDEPCCGNTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.4%) IPR017853 (9.4%) IPR036962 (9.4%)" "Glycoside hydrolase, family 3, N-terminal (9.4%) Glycoside hydrolase superfamily (9.4%) Glycoside hydrolase, family 3, N-terminal domain superfamily (9.4%)" FVDNLVFK root "2.4.1.- (50%) 6.2.1.3 (50%)" "Hexosyltransferases (50%) long-chain-fatty-acid--CoA ligase (50%)" "GO:0005975 (26.4%) GO:0070085 (0.8%)" "GO:0005576 (26.4%) GO:0016020 (2.4%) GO:0005783 (1.6%)" "GO:0004650 (26.4%) GO:0004557 (8.8%) GO:0004467 (1.6%)" "carbohydrate metabolic process (26.4%) obsolete glycosylation (0.8%)" "extracellular region (26.4%) membrane (2.4%) endoplasmic reticulum (1.6%)" "polygalacturonase activity (26.4%) alpha-galactosidase activity (8.8%) long-chain fatty acid-CoA ligase activity (1.6%)" "IPR000743 (25.8%) IPR011050 (25%) IPR012334 (25%)" "Glycoside hydrolase, family 28 (25.8%) Pectin lyase fold/virulence factor (25%) Pectin lyase fold (25%)" LLLDLLQADDGFVESNGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.5%) IPR003593 (20.5%) IPR017871 (20.5%)" "ABC transporter-like, ATP-binding domain (20.5%) AAA+ ATPase domain (20.5%) ABC transporter-like, conserved site (20.5%)" QFCTDVNVLPLDSLYTPLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011262 (16.8%) IPR011263 (16.8%) IPR011773 (16.8%)" "DNA-directed RNA polymerase, insert domain (16.8%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.8%) DNA-directed RNA polymerase, alpha subunit (16.8%)" TYDDLDYNFLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.1.9 (100%) enoyl-[acyl-carrier-protein] reductase (NADH) (100%) GO:0006633 (50%) GO:0004318 (50%) fatty acid biosynthetic process (50%) enoyl-[acyl-carrier-protein] reductase (NADH) activity (50%) "IPR002347 (34.1%) IPR014358 (34.1%) IPR036291 (31.8%)" "Short-chain dehydrogenase/reductase SDR (34.1%) Enoyl-[acyl-carrier-protein] reductase (NADH) (34.1%) NAD(P)-binding domain superfamily (31.8%)" LPNLFDASSVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (75%) GO:0005737 (8.3%) GO:0005886 (8.3%)" "extracellular space (75%) cytoplasm (8.3%) plasma membrane (8.3%)" "IPR001611 (16.8%) IPR027899 (15.6%) IPR032675 (15.6%)" "Leucine-rich repeat (16.8%) Domain of unknown function DUF4458 (15.6%) Leucine-rich repeat domain superfamily (15.6%)" EMLGGMFGNASAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20.2%) GO:0006189 (19.4%)" "GO:0004637 (20.2%) GO:0005524 (20.2%) GO:0046872 (20.2%)" "purine nucleobase biosynthetic process (20.2%) 'de novo' IMP biosynthetic process (19.4%)" "phosphoribosylamine-glycine ligase activity (20.2%) ATP binding (20.2%) metal ion binding (20.2%)" "IPR000115 (11.6%) IPR011761 (11.6%) IPR020561 (11.6%)" "Phosphoribosylglycinamide synthetase (11.6%) ATP-grasp fold (11.6%) Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain (11.6%)" GKGDPAGWVAPVTPGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) GO:0022625 (20%) "GO:0003735 (20%) GO:0019843 (20%) GO:0000049 (19.8%)" translation (20%) cytosolic large ribosomal subunit (20%) "structural constituent of ribosome (20%) rRNA binding (20%) tRNA binding (19.8%)" "IPR000114 (20%) IPR016180 (20%) IPR020798 (20%)" "Large ribosomal subunit protein uL16, bacteria (20%) Large ribosomal subunit protein uL16 domain (20%) Large ribosomal subunit protein uL16, conserved site (20%)" DGTADVLNDNRPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR020058 (10.8%) IPR050132 (10.8%) IPR004514 (10.3%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.8%) Glutamine/Glutamate--tRNA Ligase (10.8%) Glutamine-tRNA synthetase (10.3%)" NPWDEYEALYTPGSVHQGTLTELMDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.6%) IPR012340 (24.6%) IPR035104 (24.6%)" "S1 domain (24.6%) Nucleic acid-binding, OB-fold (24.6%) Ribosomal protein S1-like (24.6%)" TYLGVGVDQHSNALGEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.4%) IPR022615 (20.4%) IPR056147 (20.4%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.4%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.4%) NqrA, N-terminal barrel-sandwich hybrid domain (20.4%)" ADVGATQDLPEACK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.6%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.6%)" "IPR001030 (11.4%) IPR050926 (11.4%) IPR000573 (11.1%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.4%) Aconitase/IPM Isomerase (11.4%) Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.1%)" FATDTDEELEVLRK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.4.3 (100%) formate--tetrahydrofolate ligase (100%) "GO:0035999 (32.3%) GO:0006730 (1.1%)" "GO:0004329 (33.3%) GO:0005524 (33.3%)" "tetrahydrofolate interconversion (32.3%) one-carbon metabolic process (1.1%)" "formate-tetrahydrofolate ligase activity (33.3%) ATP binding (33.3%)" "IPR000559 (34.4%) IPR020628 (33.3%) IPR027417 (32.2%)" "Formate-tetrahydrofolate ligase, FTHFS (34.4%) Formate-tetrahydrofolate ligase, FTHFS, conserved site (33.3%) P-loop containing nucleoside triphosphate hydrolase (32.2%)" GHAVANGLPVLAVNR Pseudomonadati Bacteria Pseudomonadati "3.5.1.77 (53.3%) 3.5.1.53 (33.3%) 3.5.1.4 (6.7%)" "N-carbamoyl-D-amino-acid hydrolase (53.3%) N-carbamoylputrescine amidase (33.3%) amidase (6.7%)" GO:0033388 (43.2%) "GO:0050126 (43.2%) GO:0016746 (10.1%) GO:0047417 (2.9%)" putrescine biosynthetic process from arginine (43.2%) "N-carbamoylputrescine amidase activity (43.2%) acyltransferase activity (10.1%) N-carbamoyl-D-amino acid hydrolase activity (2.9%)" "IPR003010 (33.5%) IPR050345 (33.5%) IPR036526 (33%)" "Carbon-nitrogen hydrolase (33.5%) Aliphatic Amidase/Beta-Ureidopropionase (33.5%) Carbon-nitrogen hydrolase superfamily (33%)" GQTYFANQMYEQALK Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) "IPR019734 (34.2%) IPR011990 (32.9%) IPR018704 (32.9%)" "Tetratricopeptide repeat (34.2%) Tetratricopeptide-like helical domain superfamily (32.9%) Ancillary SecYEG translocon subunit/Cell division coordinator CpoB, TPR domain (32.9%)" KMSEYGVMLAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (19.6%) GO:0042274 (19.6%)" "GO:0015935 (19.6%) GO:0005840 (1%)" "GO:0019843 (20.6%) GO:0003735 (19.6%)" "translation (19.6%) ribosomal small subunit biogenesis (19.6%)" "small ribosomal subunit (19.6%) ribosome (1%)" "rRNA binding (20.6%) structural constituent of ribosome (19.6%)" "IPR001912 (17.2%) IPR036986 (17.2%) IPR002942 (16.4%)" "Small ribosomal subunit protein uS4, N-terminal (17.2%) RNA-binding S4 domain superfamily (17.2%) RNA-binding S4 domain (16.4%)" KSQEDWSEQL Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.9%) GO:0022900 (14.1%) GO:0044281 (13.4%)" "GO:0030976 (14.5%) GO:0005506 (14.1%) GO:0051539 (14.1%)" "response to oxidative stress (14.9%) electron transport chain (14.1%) small molecule metabolic process (13.4%)" "thiamine pyrophosphate binding (14.5%) iron ion binding (14.1%) 4 iron, 4 sulfur cluster binding (14.1%)" "IPR050722 (8.1%) IPR011766 (7.9%) IPR029061 (7.9%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Thiamin diphosphate-binding fold (7.9%)" VAEQTVTGANPELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006101 (9.1%) IPR006102 (9.1%) IPR006103 (9.1%)" "Glycoside hydrolase, family 2 (9.1%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (9.1%) Glycoside hydrolase family 2, catalytic domain (9.1%)" KQPLEMNFGYGFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" YVEPLLTR root "GO:0006412 (31.8%) GO:0006281 (0.2%) GO:0006364 (0.2%)" "GO:0022625 (31.8%) GO:0005886 (0.6%) GO:0005730 (0.2%)" "GO:0003735 (31.8%) GO:0022857 (0.4%) GO:0000166 (0.2%)" "translation (31.8%) DNA repair (0.2%) rRNA processing (0.2%)" "cytosolic large ribosomal subunit (31.8%) plasma membrane (0.6%) nucleolus (0.2%)" "structural constituent of ribosome (31.8%) transmembrane transporter activity (0.4%) nucleotide binding (0.2%)" "IPR000456 (32.1%) IPR036373 (31.9%) IPR047859 (31%)" "Large ribosomal subunit protein bL17 (32.1%) Large ribosomal subunit protein bL17 superfamily (31.9%) Large ribosomal subunit protein bL17, conserved site (31%)" LALLYYADGEKR root "GO:0002181 (19.8%) GO:0032543 (0.2%)" "GO:0015934 (19.8%) GO:0005762 (0.2%) GO:0009507 (0.2%)" "GO:0003735 (19.9%) GO:0016740 (19.9%) GO:0019843 (19.4%)" "cytoplasmic translation (19.8%) mitochondrial translation (0.2%)" "large ribosomal subunit (19.8%) mitochondrial large ribosomal subunit (0.2%) chloroplast (0.2%)" "structural constituent of ribosome (19.9%) transferase activity (19.9%) rRNA binding (19.4%)" "IPR002171 (11.2%) IPR005880 (11.2%) IPR008991 (11.2%)" "Large ribosomal subunit protein uL2 (11.2%) Large ribosomal subunit protein uL2, bacteria/organella (11.2%) Translation protein SH3-like domain superfamily (11.2%)" FMGFSFDDTDVYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (51.4%) "GO:0016787 (45.9%) GO:0016798 (2.7%)" carbohydrate metabolic process (51.4%) "hydrolase activity (45.9%) hydrolase activity, acting on glycosyl bonds (2.7%)" "IPR012878 (17.3%) IPR049046 (17.3%) IPR049049 (17.3%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.3%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.3%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17.3%)" VQFAGLTK root 5.4.99.- (100%) Transferring other groups (100%) "GO:0000455 (32.9%) GO:0001522 (0.3%) GO:0006364 (0.3%)" "GO:0003723 (33.1%) GO:0120159 (32.9%) GO:0009982 (0.3%)" "enzyme-directed rRNA pseudouridine synthesis (32.9%) pseudouridine synthesis (0.3%) rRNA processing (0.3%)" "RNA binding (33.1%) rRNA pseudouridine synthase activity (32.9%) pseudouridine synthase activity (0.3%)" "IPR000748 (11.2%) IPR006145 (11.2%) IPR050343 (11.2%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.2%) Pseudouridine synthase, RsuA/RluA-like (11.2%) Ribosomal RNA Pseudouridine Synthase RsuA (11.2%)" GLEYVDFRPNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20%) GO:0005829 (20%) "GO:0003994 (20%) GO:0046872 (20%) GO:0051539 (20%)" tricarboxylic acid cycle (20%) cytosol (20%) "aconitate hydratase activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR000573 (11.1%) IPR001030 (11.1%) IPR006248 (11.1%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.1%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.1%) Aconitase, mitochondrial-like (11.1%)" AAFFAYETLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (26.3%) GO:0009341 (26.3%) "GO:0004565 (26.3%) GO:0030246 (21.3%)" lactose catabolic process (26.3%) beta-galactosidase complex (26.3%) "beta-galactosidase activity (26.3%) carbohydrate binding (21.3%)" "IPR050347 (8.9%) IPR004199 (8%) IPR006102 (8%)" "Bacterial Beta-galactosidase (8.9%) Beta galactosidase small chain/ domain 5 (8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8%)" WEMVEALR root 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (25.9%) GO:0008654 (25.9%)" GO:0016020 (22.3%) GO:0004512 (25.9%) "inositol biosynthetic process (25.9%) phospholipid biosynthetic process (25.9%)" membrane (22.3%) inositol-3-phosphate synthase activity (25.9%) "IPR002587 (34%) IPR013021 (33%) IPR036291 (33%)" "Myo-inositol-1-phosphate synthase (34%) Myo-inositol-1-phosphate synthase, GAPDH-like (33%) NAD(P)-binding domain superfamily (33%)" WFTPGLGLR root "GO:0071973 (0.6%) GO:0006508 (0.3%) GO:0006811 (0.3%)" "GO:0016020 (48.1%) GO:0009279 (24.3%) GO:0120101 (0.6%)" "GO:0015288 (12.8%) GO:0030247 (12.5%) GO:0008233 (0.3%)" "bacterial-type flagellum-dependent cell motility (0.6%) proteolysis (0.3%) monoatomic ion transport (0.3%)" "membrane (48.1%) cell outer membrane (24.3%) bacterial-type flagellum stator complex (0.6%)" "porin activity (12.8%) polysaccharide binding (12.5%) peptidase activity (0.3%)" "IPR006665 (29.2%) IPR050330 (29.1%) IPR036737 (29%)" "OmpA-like domain (29.2%) Bacterial Outer Membrane Structural/Functional (29.1%) OmpA-like domain superfamily (29%)" TNPQAYVLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" NPPLLLLDEATSALDTESER root "3.6.3.- (93.6%) 3.6.3.44 (6.4%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (93.6%) Transferred entry: 7.6.2.2 (6.4%)" "GO:0090374 (4.1%) GO:0034220 (0%) GO:0055085 (0%)" "GO:0005886 (16.9%) GO:0005743 (3.9%) GO:0016020 (0.9%)" "GO:0005524 (21.8%) GO:0016887 (21.7%) GO:0015421 (12.4%)" "oligopeptide export from mitochondrion (4.1%) monoatomic ion transmembrane transport (0%) transmembrane transport (0%)" "plasma membrane (16.9%) mitochondrial inner membrane (3.9%) membrane (0.9%)" "ATP binding (21.8%) ATP hydrolysis activity (21.7%) ABC-type oligopeptide transporter activity (12.4%)" "IPR039421 (14.5%) IPR003439 (14.4%) IPR017871 (14.3%)" "Type 1 protein exporter (14.5%) ABC transporter-like, ATP-binding domain (14.4%) ABC transporter-like, conserved site (14.3%)" STPLGALAQFAAQGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.6%) GO:0022900 (14.4%) GO:0044281 (13.2%)" "GO:0030976 (14.6%) GO:0005506 (14.4%) GO:0051539 (14.4%)" "response to oxidative stress (14.6%) electron transport chain (14.4%) small molecule metabolic process (13.2%)" "thiamine pyrophosphate binding (14.6%) iron ion binding (14.4%) 4 iron, 4 sulfur cluster binding (14.4%)" "IPR011766 (7.9%) IPR050722 (7.9%) IPR002880 (7.8%)" "Thiamine pyrophosphate enzyme, TPP-binding (7.9%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.9%) Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%)" ASELSDFLK root "1.13.11.53 (33.3%) 1.13.11.54 (33.3%) 3.4.24.- (33.3%)" "acireductone dioxygenase (Ni(2+)-requiring) (33.3%) acireductone dioxygenase (Fe(2+)-requiring) (33.3%) Metalloendopeptidases (33.3%)" "GO:0006508 (28.9%) GO:0019284 (0.8%) GO:0019509 (0.8%)" "GO:0005769 (0.8%) GO:0005770 (0.8%) GO:0005886 (0.8%)" "GO:0004222 (28.9%) GO:0046872 (27.3%) GO:0000149 (0.8%)" "proteolysis (28.9%) L-methionine salvage from S-adenosylmethionine (0.8%) L-methionine salvage from methylthioadenosine (0.8%)" "early endosome (0.8%) late endosome (0.8%) plasma membrane (0.8%)" "metalloendopeptidase activity (28.9%) metal ion binding (27.3%) SNARE binding (0.8%)" "IPR001431 (18.7%) IPR007863 (18.7%) IPR011765 (18.7%)" "Peptidase M16, zinc-binding site (18.7%) Peptidase M16, C-terminal (18.7%) Peptidase M16, N-terminal (18.7%)" WNAFSDASTGGQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VATETALENSVSVFHLDNDEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.7%) GO:0005886 (19.7%) "GO:0003723 (20.4%) GO:0016787 (20.4%) GO:0004521 (19.7%)" mRNA catabolic process (19.7%) plasma membrane (19.7%) "RNA binding (20.4%) hydrolase activity (20.4%) RNA endonuclease activity (19.7%)" "IPR003607 (12.6%) IPR004087 (12.6%) IPR004088 (12.6%)" "HD/PDEase domain (12.6%) K Homology domain (12.6%) K Homology domain, type 1 (12.6%)" SLSFVEQLVEEDLKEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR020058 (10.8%) IPR050132 (10.8%) IPR004514 (10.4%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.8%) Glutamine/Glutamate--tRNA Ligase (10.8%) Glutamine-tRNA synthetase (10.4%)" LGAFGWTGSYAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR010870 (51.1%) IPR023614 (48.9%)" "Phosphate-selective porin O/P (51.1%) Porin domain superfamily (48.9%)" EALSFYDEASSSWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" SQHADVLETLGDGKLTDDALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17%) GO:0045259 (17%)" "GO:0005524 (17%) GO:0043531 (17%) GO:0046933 (17%)" "plasma membrane (17%) proton-transporting ATP synthase complex (17%)" "ATP binding (17%) ADP binding (17%) proton-transporting ATP synthase activity, rotational mechanism (17%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" ELAFLNAGLK Bacteria Bacteria 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (15.1%) GO:0006261 (9.5%) GO:0032259 (0.2%)" "GO:0005694 (9.9%) GO:0005737 (9.7%)" "GO:0003677 (15.1%) GO:0005524 (15.1%) GO:0046872 (10.1%)" "DNA topological change (15.1%) DNA-templated DNA replication (9.5%) methylation (0.2%)" "chromosome (9.9%) cytoplasm (9.7%)" "DNA binding (15.1%) ATP binding (15.1%) metal ion binding (10.1%)" "IPR001241 (8.3%) IPR000565 (8.2%) IPR006171 (8.2%)" "DNA topoisomerase, type IIA (8.3%) DNA topoisomerase, type IIA, subunit B (8.2%) TOPRIM domain (8.2%)" VSLPGYVFVEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006354 (20.8%) GO:0031564 (20.8%) GO:0006353 (18.9%)" GO:0005829 (20.8%) "DNA-templated transcription elongation (20.8%) transcription antitermination (20.8%) DNA-templated transcription termination (18.9%)" cytosol (20.8%) "IPR006645 (13.1%) IPR036735 (13.1%) IPR043425 (13.1%)" "NusG-like, N-terminal (13.1%) NusG, N-terminal domain superfamily (13.1%) NusG-like (13.1%)" GTVANVVMASLNAYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0017038 (47.1%) "GO:0005886 (47.1%) GO:0016020 (5.9%)" protein import (47.1%) "plasma membrane (47.1%) membrane (5.9%)" "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" MLLDLEMLR Pseudomonadati Bacteria Pseudomonadati "4.2.1.3 (97.7%) 3.6.3.- (2.3%)" "aconitate hydratase (97.7%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (2.3%)" "GO:0006099 (18.2%) GO:0015833 (1.7%) GO:0055085 (1.7%)" "GO:0005829 (18.2%) GO:0005886 (2.1%)" "GO:0003994 (18.2%) GO:0051539 (18.2%) GO:0046872 (17.8%)" "tricarboxylic acid cycle (18.2%) peptide transport (1.7%) transmembrane transport (1.7%)" "cytosol (18.2%) plasma membrane (2.1%)" "aconitate hydratase activity (18.2%) 4 iron, 4 sulfur cluster binding (18.2%) metal ion binding (17.8%)" "IPR001030 (10.6%) IPR050926 (10.6%) IPR000573 (10.4%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (10.6%) Aconitase/IPM Isomerase (10.6%) Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (10.4%)" NALLENVTVAADGK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.7%) GO:0005829 (17.7%) "GO:0004612 (17.7%) GO:0005524 (17.7%) GO:0046872 (17.7%)" gluconeogenesis (17.7%) cytosol (17.7%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.7%) ATP binding (17.7%) metal ion binding (17.7%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" FLTSTFYMDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.1.3.1 (100%) alkaline phosphatase (100%) GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (34.5%) IPR026263 (33.6%) IPR017850 (31.9%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (34.5%) Alkaline phosphatase, prokaryotic (33.6%) Alkaline-phosphatase-like, core domain superfamily (31.9%)" AEVYLQPEEVSLALGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006353 (19.6%) GO:0031564 (19.6%)" GO:0005829 (19.6%) "GO:0003723 (19.6%) GO:0003700 (19.3%) GO:0003746 (2.4%)" "DNA-templated transcription termination (19.6%) transcription antitermination (19.6%)" cytosol (19.6%) "RNA binding (19.6%) DNA-binding transcription factor activity (19.3%) translation elongation factor activity (2.4%)" "IPR025249 (11.4%) IPR030842 (11.4%) IPR009019 (11.2%)" "Transcription factor NusA, first KH domain (11.4%) Transcription factor NusA, prokaryotes (11.4%) K homology domain superfamily, prokaryotic type (11.2%)" KLGVAGLLTDGETGQTAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.40 (100%) pyruvate kinase (100%) "GO:0004743 (20.6%) GO:0016301 (20.6%) GO:0000287 (19.6%)" "pyruvate kinase activity (20.6%) kinase activity (20.6%) magnesium ion binding (19.6%)" "IPR015795 (11.9%) IPR001697 (11.3%) IPR015793 (11.3%)" "Pyruvate kinase, C-terminal (11.9%) Pyruvate kinase (11.3%) Pyruvate kinase, barrel (11.3%)" LNPADLYVTVFEGSKEEGLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" VSTAVGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.271 (100%) GDP-L-fucose synthase (100%) GO:0042351 (25%) "GO:0016853 (25%) GO:0050577 (25%) GO:0070401 (25%)" 'de novo' GDP-L-fucose biosynthetic process (25%) "isomerase activity (25%) GDP-L-fucose synthase activity (25%) NADP+ binding (25%)" "IPR001509 (33.3%) IPR028614 (33.3%) IPR036291 (33.3%)" "NAD-dependent epimerase/dehydratase (33.3%) GDP-L-fucose synthase/GDP-L-colitose synthase (33.3%) NAD(P)-binding domain superfamily (33.3%)" LTNAGVLESHPHDLTLTSEAPNYSRPE Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (19.8%) GO:0006183 (19.8%)" "GO:0000166 (19.8%) GO:0003938 (19.8%) GO:0046872 (19.8%)" "GMP biosynthetic process (19.8%) GTP biosynthetic process (19.8%)" "nucleotide binding (19.8%) IMP dehydrogenase activity (19.8%) metal ion binding (19.8%)" "IPR001093 (17.6%) IPR000644 (16.9%) IPR005990 (16.9%)" "IMP dehydrogenase/GMP reductase (17.6%) CBS domain (16.9%) Inosine-5'-monophosphate dehydrogenase (16.9%)" SGFACAFSATTPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.5 (96.8%) 3.1.3.6 (3.2%)" "5'-nucleotidase (96.8%) 3'-nucleotidase (3.2%)" GO:0005737 (23.4%) "GO:0000166 (23.4%) GO:0008253 (23.4%) GO:0046872 (23.4%)" cytoplasm (23.4%) "nucleotide binding (23.4%) 5'-nucleotidase activity (23.4%) metal ion binding (23.4%)" "IPR002828 (34.1%) IPR030048 (34.1%) IPR036523 (31.8%)" "Survival protein SurE-like phosphatase/nucleotidase (34.1%) Survival protein SurE (34.1%) SurE-like phosphatase/nucleotidase superfamily (31.8%)" DLVNLMEGVEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20%) GO:0006102 (20%)" "GO:0000287 (20%) GO:0004450 (20%) GO:0051287 (20%)" "tricarboxylic acid cycle (20%) isocitrate metabolic process (20%)" "magnesium ion binding (20%) isocitrate dehydrogenase (NADP+) activity (20%) NAD binding (20%)" "IPR004790 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isocitrate dehydrogenase NADP-dependent (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" YLDTLQDGYGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004553 (100%) hydrolase activity, hydrolyzing O-glycosyl compounds (100%) "IPR017853 (50%) IPR022790 (50%)" "Glycoside hydrolase superfamily (50%) Glycosyl hydrolase family 26 domain (50%)" LLNDGTFSNLSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" QQLFNASLNETLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" SSYNNLYWVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.7%) IPR011990 (32.7%) IPR033985 (32.7%)" "RagB/SusD domain (34.7%) Tetratricopeptide-like helical domain superfamily (32.7%) SusD-like, N-terminal (32.7%)" QGMDLFAGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.2%) IPR006512 (25.2%) IPR050144 (25.2%)" "Regulator of K+ conductance, C-terminal (25.2%) YidE/YbjL duplication (25.2%) AAE Transporter (25.2%)" NYWLGSDGVLYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR011250 (25.8%) IPR006664 (16.7%) IPR006665 (16.7%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (25.8%) Outer membrane protein, bacterial (16.7%) OmpA-like domain (16.7%)" GQETYGEDPYLTSR root "3.2.1.37 (51.9%) 3.2.1.21 (48.1%)" "xylan 1,4-beta-xylosidase (51.9%) beta-glucosidase (48.1%)" "GO:0031222 (23.9%) GO:0045493 (23.9%)" GO:0016020 (0.2%) "GO:0009044 (23.9%) GO:0046556 (23.9%) GO:0008422 (4.1%)" "arabinan catabolic process (23.9%) xylan catabolic process (23.9%)" membrane (0.2%) "xylan 1,4-beta-xylosidase activity (23.9%) alpha-L-arabinofuranosidase activity (23.9%) beta-glucosidase activity (4.1%)" "IPR001764 (10%) IPR044993 (10%) IPR017853 (9.9%)" "Glycoside hydrolase, family 3, N-terminal (10%) Beta-D-xylosidase (10%) Glycoside hydrolase superfamily (9.9%)" LGDVDLVLGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009055 (100%) electron transfer activity (100%) "IPR000049 (20%) IPR012255 (20%) IPR014729 (20%)" "Electron transfer flavoprotein, beta-subunit, conserved site (20%) Electron transfer flavoprotein, beta subunit (20%) Rossmann-like alpha/beta/alpha sandwich fold (20%)" WEWFPSK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (2.3%) GO:0009279 (97.7%) iron ion transport (2.3%) cell outer membrane (97.7%) "IPR000531 (20.8%) IPR012910 (20.8%) IPR036942 (19.8%)" "TonB-dependent receptor-like, beta-barrel (20.8%) TonB-dependent receptor, plug domain (20.8%) TonB-dependent receptor-like, beta-barrel domain superfamily (19.8%)" ELSPLDGLK Pseudomonadati Bacteria Pseudomonadati 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (49.7%) "GO:0008422 (49.3%) GO:0016787 (0.7%) GO:0004553 (0.3%)" carbohydrate metabolic process (49.7%) "beta-glucosidase activity (49.3%) hydrolase activity (0.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (0.3%)" "IPR001764 (11.2%) IPR002772 (11.2%) IPR050288 (11.2%)" "Glycoside hydrolase, family 3, N-terminal (11.2%) Glycoside hydrolase family 3 C-terminal domain (11.2%) Cellulose-degrading glycosyl hydrolase 3 (11.2%)" VRPNLALGER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LTEAVGQSTNPANYLLAQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006508 (4.1%) "GO:0005886 (45.9%) GO:0098552 (45.9%)" GO:0008233 (4.1%) proteolysis (4.1%) "plasma membrane (45.9%) side of membrane (45.9%)" peptidase activity (4.1%) "IPR001107 (21.3%) IPR018080 (21.3%) IPR036013 (21.3%)" "Band 7 domain (21.3%) Band 7/stomatin-like, conserved site (21.3%) Band 7/SPFH domain superfamily (21.3%)" MNMNLQDGVALAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.6%) GO:0006096 (12.6%) GO:0019563 (12.6%)" "GO:0005829 (12.6%) GO:0016020 (12.3%)" GO:0004807 (12.6%) "gluconeogenesis (12.6%) glycolytic process (12.6%) glycerol catabolic process (12.6%)" "cytosol (12.6%) membrane (12.3%)" triose-phosphate isomerase activity (12.6%) "IPR000652 (16.9%) IPR020861 (16.9%) IPR022896 (16.9%)" "Triosephosphate isomerase (16.9%) Triosephosphate isomerase, active site (16.9%) Triosephosphate isomerase, bacterial/eukaryotic (16.9%)" AWQTTGNWLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.1%) IPR011990 (32.4%) IPR012944 (32.4%)" "SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (32.4%) RagB/SusD domain (32.4%)" GFEMMVR root "GO:0005975 (46.4%) GO:0007059 (1%) GO:0044718 (1%)" "GO:0005694 (1%) GO:0009279 (1%)" "GO:0004553 (46.4%) GO:0003677 (1%) GO:0008835 (1%)" "carbohydrate metabolic process (46.4%) chromosome segregation (1%) siderophore transmembrane transport (1%)" "chromosome (1%) cell outer membrane (1%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (46.4%) DNA binding (1%) diaminohydroxyphosphoribosylaminopyrimidine deaminase activity (1%)" "IPR001764 (11.5%) IPR050288 (11.5%) IPR002772 (10.9%)" "Glycoside hydrolase, family 3, N-terminal (11.5%) Cellulose-degrading glycosyl hydrolase 3 (11.5%) Glycoside hydrolase family 3 C-terminal domain (10.9%)" DYTHTDVLTDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (12.7%) IPR023996 (12.7%) IPR023997 (12.7%)" "TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.7%)" LAQEGVGSFYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) QYNEALAQYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019734 (52.6%) IPR011990 (47.4%)" "Tetratricopeptide repeat (52.6%) Tetratricopeptide-like helical domain superfamily (47.4%)" LDYYWMMGDNR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (24.9%) IPR019533 (24.9%) IPR019758 (24.6%)" "Peptidase S26A, signal peptidase I (24.9%) Peptidase S26 (24.9%) Peptidase S26A, signal peptidase I, conserved site (24.6%)" VLMESLAPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25.2%) IPR010190 (25.2%) IPR032094 (25.2%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.2%) Diaminopimelate dehydrogenase, Ddh (25.2%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25.2%)" DDLYDKFVEDVTAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.6 (100%) galactokinase (100%) GO:0006012 (20%) GO:0005829 (20%) "GO:0004335 (20%) GO:0005524 (20%) GO:0046872 (20%)" galactose metabolic process (20%) cytosol (20%) "galactokinase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR000705 (10.2%) IPR006203 (10.2%) IPR006204 (10.2%)" "Galactokinase (10.2%) GHMP kinase, ATP-binding, conserved site (10.2%) GHMP kinase N-terminal domain (10.2%)" FLTEYVLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.75 (100%) tRNA dimethylallyltransferase (100%) GO:0006400 (33.7%) "GO:0052381 (33.7%) GO:0005524 (32.6%)" tRNA modification (33.7%) "tRNA dimethylallyltransferase activity (33.7%) ATP binding (32.6%)" "IPR039657 (34.1%) IPR018022 (33%) IPR027417 (33%)" "Dimethylallyltransferase (34.1%) IPP transferase (33%) P-loop containing nucleoside triphosphate hydrolase (33%)" EWNATLLDLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009100 (100%) glycoprotein metabolic process (100%) "IPR007074 (48.6%) IPR052942 (48.6%) IPR043519 (2.7%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (48.6%) Lipopolysaccharide cholinephosphotransferase (48.6%) Nucleotidyltransferase superfamily (2.7%)" VADGLLEVELPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (34.8%) IPR031107 (34.8%) IPR008978 (30.4%)" "Alpha crystallin/Hsp20 domain (34.8%) Small heat shock protein (34.8%) HSP20-like chaperone (30.4%)" LLSQTLLEELAEQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR011050 (33.3%) IPR012334 (33.3%) IPR033427 (33.3%)" "Pectin lyase fold/virulence factor (33.3%) Pectin lyase fold (33.3%) Domain of unknown function DUF5123 (33.3%)" ACLLGSLR root GO:0060271 (5.9%) "GO:0016020 (35.3%) GO:0005737 (11.8%)" "GO:0005524 (11.8%) GO:0016887 (11.8%) GO:0140359 (11.8%)" cilium assembly (5.9%) "membrane (35.3%) cytoplasm (11.8%)" "ATP binding (11.8%) ATP hydrolysis activity (11.8%) ABC-type transporter activity (11.8%)" "IPR015943 (28.6%) IPR003439 (4.8%) IPR003593 (4.8%)" "WD40/YVTN repeat-like-containing domain superfamily (28.6%) ABC transporter-like, ATP-binding domain (4.8%) AAA+ ATPase domain (4.8%)" ALCQPFDFLLADEPLSHLDDNNSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25%) "GO:0005524 (25%) GO:0016887 (25%) GO:0022857 (25%)" plasma membrane (25%) "ATP binding (25%) ATP hydrolysis activity (25%) transmembrane transporter activity (25%)" "IPR003439 (34.1%) IPR015854 (34.1%) IPR027417 (31.7%)" "ABC transporter-like, ATP-binding domain (34.1%) ABC transporter, lipoprotein release, LolD-like (34.1%) P-loop containing nucleoside triphosphate hydrolase (31.7%)" SDNGYFNYYAALGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" KSALETMNSAEMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" YRPFTENNADAGFDNNLNYNNNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" MMLYMASPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35%) IPR033985 (35%) IPR011990 (30%)" "RagB/SusD domain (35%) SusD-like, N-terminal (35%) Tetratricopeptide-like helical domain superfamily (30%)" LLAMNESGK root "GO:0000028 (16.5%) GO:0006412 (16.5%)" "GO:0005737 (16.5%) GO:0015935 (16.5%) GO:0005886 (0.2%)" "GO:0003735 (16.5%) GO:0019843 (16.5%) GO:0005524 (0.3%)" "ribosomal small subunit assembly (16.5%) translation (16.5%)" "cytoplasm (16.5%) small ribosomal subunit (16.5%) plasma membrane (0.2%)" "structural constituent of ribosome (16.5%) rRNA binding (16.5%) ATP binding (0.3%)" "IPR002222 (24%) IPR005732 (24%) IPR020934 (24%)" "Small ribosomal subunit protein uS19 (24%) Small ribosomal subunit protein uS19, bacteria (24%) Small ribosomal subunit protein uS19, conserved site (24%)" LQAFLEK root "4.2.1.17 (44.5%) 5.6.2.4 (10.6%) 3.6.4.12 (4.4%)" "enoyl-CoA hydratase (44.5%) DNA 3'-5' helicase (10.6%) DNA helicase (4.4%)" "GO:0006635 (6.9%) GO:0006631 (1.7%) GO:0006606 (1.5%)" "GO:0005829 (4.5%) GO:0005737 (1.8%) GO:0016020 (1.8%)" "GO:0005524 (4%) GO:0016836 (3.8%) GO:0016829 (2.4%)" "fatty acid beta-oxidation (6.9%) fatty acid metabolic process (1.7%) protein import into nucleus (1.5%)" "cytosol (4.5%) cytoplasm (1.8%) membrane (1.8%)" "ATP binding (4%) hydro-lyase activity (3.8%) lyase activity (2.4%)" "IPR029045 (8.5%) IPR001753 (8.4%) IPR018376 (4.9%)" "ClpP/crotonase-like domain superfamily (8.5%) Enoyl-CoA hydratase/isomerase (8.4%) Enoyl-CoA hydratase/isomerase, conserved site (4.9%)" LNGAAVYALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" TADAGYLTR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (16.8%) GO:0006412 (0%) GO:0006633 (0%)" "GO:0000428 (16.8%) GO:0009507 (6.9%) GO:0009536 (1.2%)" "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0008270 (14.1%)" "DNA-templated transcription (16.8%) translation (0%) fatty acid biosynthetic process (0%)" "DNA-directed RNA polymerase complex (16.8%) chloroplast (6.9%) plastid (1.2%)" "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) zinc ion binding (14.1%)" "IPR007081 (11.9%) IPR038120 (11.7%) IPR042102 (11.5%)" "RNA polymerase Rpb1, domain 5 (11.9%) RNA polymerase Rpb1, funnel domain superfamily (11.7%) RNA polymerase Rpb1, domain 3 superfamily (11.5%)" LTLTGNLGDVMK root "3.4.21.53 (99.6%) 3.4.21.- (0.4%)" "endopeptidase La (99.6%) Serine endopeptidases (0.4%)" "GO:0006515 (12%) GO:0034605 (12%) GO:0006508 (0.6%)" "GO:0005737 (12.3%) GO:0016020 (0%)" "GO:0004176 (12.6%) GO:0004252 (12.6%) GO:0005524 (12.6%)" "protein quality control for misfolded or incompletely synthesized proteins (12%) cellular response to heat (12%) proteolysis (0.6%)" "cytoplasm (12.3%) membrane (0%)" "ATP-dependent peptidase activity (12.6%) serine-type endopeptidase activity (12.6%) ATP binding (12.6%)" "IPR008269 (7.2%) IPR027065 (7.2%) IPR014721 (7.2%)" "Peptidase S16, Lon proteolytic domain (7.2%) Lon protease (7.2%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (7.2%)" ASVPSGASTGENEALELR Bacteria Bacteria 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.9%) "GO:0000015 (16.9%) GO:0005576 (16.4%) GO:0009986 (16.1%)" "GO:0000287 (16.9%) GO:0004634 (16.9%)" glycolytic process (16.9%) "phosphopyruvate hydratase complex (16.9%) extracellular region (16.4%) cell surface (16.1%)" "magnesium ion binding (16.9%) phosphopyruvate hydratase activity (16.9%)" "IPR000941 (16.8%) IPR020811 (16.8%) IPR029017 (16.7%)" "Enolase (16.8%) Enolase, N-terminal (16.8%) Enolase-like, N-terminal (16.7%)" NPLYHWTHLELK root 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" "GO:0008880 (33.3%) GO:0016853 (0.2%)" "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" "glucuronate isomerase activity (33.3%) isomerase activity (0.2%)" "IPR003766 (50.1%) IPR032466 (49.9%)" "Uronate isomerase (50.1%) Metal-dependent hydrolase (49.9%)" FFMNLSHELR root 2.7.13.3 (100%) histidine kinase (100%) "GO:0031149 (0.9%) GO:0031288 (0.9%) GO:0044671 (0.9%)" GO:0016020 (5.1%) "GO:0000155 (25.2%) GO:0003700 (23.1%) GO:0043565 (23.1%)" "sorocarp stalk cell differentiation (0.9%) sorocarp morphogenesis (0.9%) sorocarp spore cell differentiation (0.9%)" membrane (5.1%) "phosphorelay sensor kinase activity (25.2%) DNA-binding transcription factor activity (23.1%) sequence-specific DNA binding (23.1%)" "IPR001789 (7.4%) IPR003661 (7.4%) IPR005467 (7.4%)" "Signal transduction response regulator, receiver domain (7.4%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.4%) Histidine kinase domain (7.4%)" TVALFGCGDSESYPDTFCGGMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0010181 (53.3%) GO:0009055 (46.7%)" "FMN binding (53.3%) electron transfer activity (46.7%)" "IPR008254 (20.9%) IPR010086 (20.9%) IPR050619 (20.9%)" "Flavodoxin/nitric oxide synthase (20.9%) Flavodoxin, long chain (20.9%) Flavodoxin (20.9%)" LTAFGEHEDCKEAMER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (31.3%) "GO:0030170 (34.4%) GO:0010285 (31.3%) GO:0008483 (3.1%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (31.3%) "pyridoxal phosphate binding (34.4%) L,L-diaminopimelate aminotransferase activity (31.3%) transaminase activity (3.1%)" "IPR004839 (21.6%) IPR019942 (21.6%) IPR015422 (19.6%)" "Aminotransferase, class I/classII, large domain (21.6%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21.6%) Pyridoxal phosphate-dependent transferase, small domain (19.6%)" LKLEDDDLVLPEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.5.1.7 (100%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0019277 (14.3%)" GO:0005737 (14.3%) GO:0008760 (14.3%) "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) UDP-N-acetylgalactosamine biosynthetic process (14.3%)" cytoplasm (14.3%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity (14.3%) "IPR001986 (20%) IPR005750 (20%) IPR013792 (20%)" "Enolpyruvate transferase domain (20%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (20%) RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta (20%)" GDGVFQFANPSDMPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" CEPQKLDELLHPVFDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0005524 (25%) GO:0016301 (25%) GO:0046872 (25%)" "ATP binding (25%) kinase activity (25%) metal ion binding (25%)" "IPR000121 (10%) IPR002192 (10%) IPR008279 (10%)" "PEP-utilising enzyme, C-terminal (10%) Pyruvate phosphate dikinase, AMP/ATP-binding (10%) PEP-utilising enzyme, mobile domain (10%)" QLLNSLNLR root 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (24.6%) GO:0005886 (25.4%) "GO:0010181 (24.6%) GO:0016655 (24.6%) GO:0004888 (0.7%)" sodium ion transport (24.6%) plasma membrane (25.4%) "FMN binding (24.6%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (24.6%) transmembrane signaling receptor activity (0.7%)" "IPR007329 (42.7%) IPR010204 (42.7%) IPR003961 (2.4%)" "FMN-binding (42.7%) Na(+)-translocating NADH-quinone reductase subunit C (42.7%) Fibronectin type III (2.4%)" SNSDTGSAESQLALFSYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25.3%) GO:0022627 (25.3%) "GO:0003735 (25.3%) GO:0019843 (24.2%)" translation (25.3%) cytosolic small ribosomal subunit (25.3%) "structural constituent of ribosome (25.3%) rRNA binding (24.2%)" "IPR000589 (33.3%) IPR005290 (33.3%) IPR009068 (33.3%)" "Small ribosomal subunit protein uS15 (33.3%) Small ribosomal subunit protein uS15, bacteria (33.3%) uS15/NS1, RNA-binding domain superfamily (33.3%)" EGELSPLYECGDNNHLLVVVLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.4%) IPR027304 (25.3%) IPR046357 (25.3%)" "Periplasmic chaperone PpiD (26.4%) Trigger factor/SurA domain superfamily (25.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.3%)" TFMDYLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.1%) IPR033985 (35.1%) IPR011990 (29.7%)" "RagB/SusD domain (35.1%) SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (29.7%)" NTTGVLLLTNDGDLASK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "5.4.99.- (98.6%) 5.4.99.22 (1.4%)" "Transferring other groups (98.6%) 23S rRNA pseudouridine(2605) synthase (1.4%)" "GO:0000455 (31.6%) GO:0001522 (1.2%) GO:0006364 (1.2%)" "GO:0003723 (32.8%) GO:0120159 (31.6%) GO:0009982 (0.9%)" "enzyme-directed rRNA pseudouridine synthesis (31.6%) pseudouridine synthesis (1.2%) rRNA processing (1.2%)" "RNA binding (32.8%) rRNA pseudouridine synthase activity (31.6%) pseudouridine synthase activity (0.9%)" "IPR006145 (11.2%) IPR018496 (11.2%) IPR050343 (11.2%)" "Pseudouridine synthase, RsuA/RluA-like (11.2%) Pseudouridine synthase, RsuA/RluB/E/F, conserved site (11.2%) Ribosomal RNA Pseudouridine Synthase RsuA (11.2%)" EGELVEKDTVLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR007066 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 3 (9.3%)" LSDHVNFLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027385 (52.2%) IPR011250 (47.8%)" "Outer membrane protein, beta-barrel domain (52.2%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (47.8%)" LGQLYACAGANR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (7.8%) IPR005225 (7.8%) IPR041095 (7.8%)" "Translational (tr)-type GTP-binding domain (7.8%) Small GTP-binding domain (7.8%) Elongation Factor G, domain II (7.8%)" ASVALSGLTVAEEFRDHGGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (23.1%) GO:0045259 (23.1%)" "GO:0005524 (23.1%) GO:0046933 (23.1%) GO:0016787 (7.7%)" "plasma membrane (23.1%) proton-transporting ATP synthase complex (23.1%)" "ATP binding (23.1%) proton-transporting ATP synthase activity, rotational mechanism (23.1%) hydrolase activity (7.7%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" SEAELLAEAVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" KPVSGLAMGLLK Bacteria Bacteria 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.2%) GO:0006401 (0.1%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.2%) RNA catabolic process (0.1%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR003029 (7.9%) IPR004087 (7.9%) IPR004088 (7.9%)" "S1 domain (7.9%) K Homology domain (7.9%) K Homology domain, type 1 (7.9%)" DLSGLTVFK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016020 (2.4%) GO:0016787 (97.6%) membrane (2.4%) hydrolase activity (97.6%) "IPR002018 (20.2%) IPR019819 (20.2%) IPR050309 (20.2%)" "Carboxylesterase, type B (20.2%) Carboxylesterase type B, conserved site (20.2%) Type-B Carboxylesterase/Lipase (20.2%)" ADLAELSPVR Pseudomonadati Bacteria Pseudomonadati 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR004499 (11.6%) IPR002314 (11.2%) IPR004154 (11.2%)" "Proline-tRNA ligase, class IIa, archaeal-type (11.6%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.2%) Anticodon-binding (11.2%)" GGMTSHAAVVAR root "2.7.9.1 (100%) 2.7.-.- (0%)" "pyruvate, phosphate dikinase (100%) Transferring phosphorus-containing groups (0%)" "GO:0015979 (1.9%) GO:0006396 (0%) GO:0009909 (0%)" "GO:0005737 (0.9%) GO:0009507 (0.1%) GO:0005829 (0%)" "GO:0050242 (24.4%) GO:0016301 (24.4%) GO:0005524 (23.9%)" "photosynthesis (1.9%) RNA processing (0%) regulation of flower development (0%)" "cytoplasm (0.9%) chloroplast (0.1%) cytosol (0%)" "pyruvate, phosphate dikinase activity (24.4%) kinase activity (24.4%) ATP binding (23.9%)" "IPR008279 (10.3%) IPR018274 (10.3%) IPR010121 (10.3%)" "PEP-utilising enzyme, mobile domain (10.3%) PEP-utilising enzyme, active site (10.3%) Pyruvate, phosphate dikinase (10.3%)" FVLSDANWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.4%) IPR051802 (19.4%) IPR001599 (18.5%)" "Macroglobulin domain (19.4%) Alpha-2-macroglobulin-like (19.4%) Alpha-2-macroglobulin (18.5%)" FGDDFELK root "2.7.11.1 (60%) 2.7.13.3 (20%) 3.6.1.23 (20%)" "non-specific serine/threonine protein kinase (60%) histidine kinase (20%) dUTP diphosphatase (20%)" "GO:0000917 (12%) GO:0043093 (12%) GO:0051258 (12%)" "GO:0005737 (12%) GO:0032153 (12%) GO:0005886 (2.3%)" "GO:0005525 (12.8%) GO:0003924 (12%) GO:0004674 (2.3%)" "division septum assembly (12%) FtsZ-dependent cytokinesis (12%) protein polymerization (12%)" "cytoplasm (12%) cell division site (12%) plasma membrane (2.3%)" "GTP binding (12.8%) GTPase activity (12%) protein serine/threonine kinase activity (2.3%)" "IPR024757 (9.6%) IPR000158 (9%) IPR003008 (9%)" "Cell division protein FtsZ, C-terminal (9.6%) Cell division protein FtsZ (9%) Tubulin/FtsZ, GTPase domain (9%)" DNHLDFAGGLDNALDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.19 (100%) nicotinate-nucleotide diphosphorylase (carboxylating) (100%) "GO:0009435 (25%) GO:0034213 (25%)" GO:0005737 (25%) GO:0004514 (25%) "NAD+ biosynthetic process (25%) quinolinate catabolic process (25%)" cytoplasm (25%) nicotinate-nucleotide diphosphorylase (carboxylating) activity (25%) "IPR002638 (14.7%) IPR004393 (14.7%) IPR022412 (14.7%)" "Quinolinate phosphoribosyl transferase, C-terminal (14.7%) Nicotinate-nucleotide pyrophosphorylase (14.7%) Quinolinate phosphoribosyl transferase, N-terminal (14.7%)" FTFEQAVEALSDDKDTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (28%) IPR050280 (26%) IPR046357 (24%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (28%) Outer Membrane Protein Chaperone SurA (26%) Peptidyl-prolyl cis-trans isomerase domain superfamily (24%)" FTRPFLTDWVLDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.7%) IPR003385 (20.7%) IPR013783 (19.5%)" "Carbohydrate binding module family 20 (20.7%) Glycoside hydrolase, family 77 (20.7%) Immunoglobulin-like fold (19.5%)" MLDPLKEHVDNNFNPLPAEYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0035435 (33.3%) GO:0016020 (33.3%) GO:0005315 (33.3%) phosphate ion transmembrane transport (33.3%) membrane (33.3%) phosphate transmembrane transporter activity (33.3%) IPR001204 (100%) Phosphate transporter (100%) SAELVYVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (23%) GO:0016020 (2%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (23%) membrane (2%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.6%) IPR003593 (14.6%) IPR011527 (14.6%)" "ABC transporter-like, ATP-binding domain (14.6%) AAA+ ATPase domain (14.6%) ABC transporter type 1, transmembrane domain (14.6%)" LLLGLMKPTDGSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.2%) IPR003593 (20.2%) IPR017871 (20.2%)" "ABC transporter-like, ATP-binding domain (20.2%) AAA+ ATPase domain (20.2%) ABC transporter-like, conserved site (20.2%)" MFEVLGFTPER Bacteria Bacteria "6.1.1.12 (72.1%) 6.1.1.23 (27.9%)" "aspartate--tRNA ligase (72.1%) aspartate--tRNA(Asn) ligase (27.9%)" GO:0006422 (17.3%) GO:0005737 (17.3%) "GO:0004815 (17.3%) GO:0005524 (17.3%) GO:0003676 (16.8%)" aspartyl-tRNA aminoacylation (17.3%) cytoplasm (17.3%) "aspartate-tRNA ligase activity (17.3%) ATP binding (17.3%) nucleic acid binding (16.8%)" "IPR004364 (9.3%) IPR002312 (9.1%) IPR004115 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.3%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%)" ALALSELAWSPVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (25%) GO:0030203 (25%)" GO:0016020 (25%) GO:0004563 (25%) "carbohydrate metabolic process (25%) glycosaminoglycan metabolic process (25%)" membrane (25%) beta-N-acetylhexosaminidase activity (25%) "IPR011658 (17.6%) IPR015883 (17.6%) IPR025705 (17.6%)" "PA14 domain (17.6%) Glycoside hydrolase family 20, catalytic domain (17.6%) Beta-hexosaminidase (17.6%)" EGLDDLVTGAYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GEAASGGLQSTGNYPGK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.8%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.8%)" EKHVPVLEPLEGGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.15.1.2 (100%) superoxide reductase (100%) GO:0019430 (32.4%) "GO:0005506 (33.8%) GO:0016491 (17.6%) GO:0050605 (16.2%)" removal of superoxide radicals (32.4%) "iron ion binding (33.8%) oxidoreductase activity (17.6%) superoxide reductase activity (16.2%)" "IPR002742 (17.3%) IPR051233 (17.3%) IPR004462 (16.5%)" "Desulfoferrodoxin, ferrous iron-binding domain (17.3%) Desulfoferrodoxin superoxide reductase (17.3%) Desulfoferrodoxin, N-terminal domain (16.5%)" SGDVMFQELLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (57.1%) "GO:0016787 (21.4%) GO:0016829 (21.4%)" carbohydrate metabolic process (57.1%) "hydrolase activity (21.4%) lyase activity (21.4%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" TPHNVLDLMEEQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.2 (100%) CTP synthase (glutamine hydrolyzing) (100%) "GO:0019856 (11.8%) GO:0044210 (11.8%) GO:0006241 (0.1%)" "GO:0005829 (11.8%) GO:0097268 (11.5%)" "GO:0003883 (11.8%) GO:0005524 (11.8%) GO:0042802 (11.8%)" "pyrimidine nucleobase biosynthetic process (11.8%) 'de novo' CTP biosynthetic process (11.8%) CTP biosynthetic process (0.1%)" "cytosol (11.8%) cytoophidium (11.5%)" "CTP synthase activity (11.8%) ATP binding (11.8%) identical protein binding (11.8%)" "IPR004468 (16.8%) IPR017926 (16.8%) IPR029062 (16.8%)" "CTP synthase (16.8%) Glutamine amidotransferase (16.8%) Class I glutamine amidotransferase-like (16.8%)" TPLTDWEK root "GO:0006108 (14.8%) GO:0097176 (1.6%) GO:0016117 (0.8%)" GO:0005737 (1.6%) "GO:0016746 (15.6%) GO:0051287 (15.6%) GO:0004470 (14.8%)" "malate metabolic process (14.8%) epoxide metabolic process (1.6%) carotenoid biosynthetic process (0.8%)" cytoplasm (1.6%) "acyltransferase activity (15.6%) NAD binding (15.6%) malic enzyme activity (14.8%)" "IPR002505 (8.5%) IPR012302 (8.5%) IPR036291 (8.5%)" "Phosphate acetyl/butaryl transferase (8.5%) Malic enzyme, NAD-binding (8.5%) NAD(P)-binding domain superfamily (8.5%)" MDYLSLLK root "1.1.1.2 (40%) 2.5.1.90 (30%) 2.5.1.- (10%)" "alcohol dehydrogenase (NADP(+)) (40%) all-trans-octaprenyl-diphosphate synthase (30%) Transferring alkyl or aryl groups, other than methyl groups (10%)" "GO:0008299 (36.2%) GO:0006066 (2.3%) GO:0006401 (1.1%)" "GO:0005634 (1.1%) GO:0005654 (1.1%) GO:0005737 (1.1%)" "GO:0004659 (32.8%) GO:0008270 (2.9%) GO:0008106 (2.3%)" "isoprenoid biosynthetic process (36.2%) alcohol metabolic process (2.3%) RNA catabolic process (1.1%)" "nucleus (1.1%) nucleoplasm (1.1%) cytoplasm (1.1%)" "prenyltransferase activity (32.8%) zinc ion binding (2.9%) alcohol dehydrogenase (NADP+) activity (2.3%)" "IPR000092 (24%) IPR033749 (24%) IPR008949 (23.3%)" "Polyprenyl synthetase-like (24%) Polyprenyl synthetase, conserved site (24%) Isoprenoid synthase domain superfamily (23.3%)" LAHAYLFCGPR Bacteria Bacteria 2.7.7.7 (100%) DNA-directed DNA polymerase (100%) GO:0006261 (16.6%) GO:0009360 (16.5%) "GO:0003887 (16.5%) GO:0005524 (16.5%) GO:0046872 (16.5%)" DNA-templated DNA replication (16.6%) DNA polymerase III complex (16.5%) "DNA-directed DNA polymerase activity (16.5%) ATP binding (16.5%) metal ion binding (16.5%)" "IPR050238 (12%) IPR027417 (12%) IPR003593 (11.9%)" "DNA Replication and Repair Clamp Loader Complex (12%) P-loop containing nucleoside triphosphate hydrolase (12%) AAA+ ATPase domain (11.9%)" KAYPENDTEVSSLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.1%) GO:0043335 (15.5%) GO:0051083 (15.5%)" GO:0005737 (6%) "GO:0003755 (15.5%) GO:0043022 (15.5%) GO:0044183 (15.5%)" "protein transport (16.1%) protein unfolding (15.5%) 'de novo' cotranslational protein folding (15.5%)" cytoplasm (6%) "peptidyl-prolyl cis-trans isomerase activity (15.5%) ribosome binding (15.5%) protein folding chaperone (15.5%)" "IPR005215 (18.8%) IPR008881 (18.8%) IPR037041 (18.8%)" "Trigger factor (18.8%) Trigger factor, ribosome-binding, bacterial (18.8%) Trigger factor, C-terminal domain superfamily (18.8%)" LDNVVFR root "7.6.2.1 (27.3%) 1.6.5.9 (9.1%) 2.1.1.190 (9.1%)" "P-type phospholipid transporter (27.3%) NADH:ubiquinone reductase (non-electrogenic) (9.1%) 23S rRNA (uracil(1939)-C(5))-methyltransferase (9.1%)" "GO:0042274 (19%) GO:0006412 (18.7%) GO:0006508 (0.2%)" "GO:0015935 (19%) GO:0009507 (0.5%) GO:0005886 (0.3%)" "GO:0019843 (19.1%) GO:0003735 (19%) GO:0016740 (0.4%)" "ribosomal small subunit biogenesis (19%) translation (18.7%) proteolysis (0.2%)" "small ribosomal subunit (19%) chloroplast (0.5%) plasma membrane (0.3%)" "rRNA binding (19.1%) structural constituent of ribosome (19%) transferase activity (0.4%)" "IPR002942 (16.5%) IPR022801 (16.5%) IPR036986 (16.5%)" "RNA-binding S4 domain (16.5%) Small ribosomal subunit protein uS4 (16.5%) RNA-binding S4 domain superfamily (16.5%)" LNFCGQLLESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0042026 (33.3%) GO:0005737 (33.3%) GO:0003755 (33.3%) protein refolding (33.3%) cytoplasm (33.3%) peptidyl-prolyl cis-trans isomerase activity (33.3%) "IPR001179 (33.3%) IPR046357 (33.3%) IPR048261 (33.3%)" "FKBP-type peptidyl-prolyl cis-trans isomerase domain (33.3%) Peptidyl-prolyl cis-trans isomerase domain superfamily (33.3%) PPIase chaperone SlpA/SlyD-like, insertion domain superfamily (33.3%)" NLLVKPVTDPLYTWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34.3%) "GO:0004553 (34.3%) GO:0030246 (31.4%)" carbohydrate metabolic process (34.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.3%) carbohydrate binding (31.4%)" "IPR000322 (12.9%) IPR048395 (12.9%) IPR051816 (12.9%)" "Glycoside hydrolase family 31, TIM barrel domain (12.9%) Glycosyl hydrolase family 31, C-terminal domain (12.9%) Glycosyl Hydrolase Family 31 (12.9%)" GVLLEPVVGWTTHHSLCEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0004553 (50%) xylan catabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (33.8%) IPR052176 (33.8%) IPR023296 (32.4%)" "Glycoside hydrolase, family 43 (33.8%) Glycosyl Hydrolase Family 43 Enzymes (33.8%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (32.4%)" YLQYHEVFEQDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri SGQGLYSFFDKER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.8%) GO:0008360 (13.7%) GO:0009252 (13.7%)" GO:0005737 (13.7%) "GO:0005524 (14.8%) GO:0008716 (14.8%) GO:0046872 (14.8%)" "cell wall organization (14.8%) regulation of cell shape (13.7%) peptidoglycan biosynthetic process (13.7%)" cytoplasm (13.7%) "ATP binding (14.8%) D-alanine-D-alanine ligase activity (14.8%) metal ion binding (14.8%)" "IPR000291 (14.4%) IPR005905 (14.4%) IPR011095 (14.4%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.4%) D-alanine--D-alanine ligase (14.4%) D-alanine--D-alanine ligase, C-terminal (14.4%)" AAWDLMSVAK Pseudomonadati Bacteria Pseudomonadati "IPR012910 (34.5%) IPR023996 (34.5%) IPR037066 (31%)" "TonB-dependent receptor, plug domain (34.5%) TonB-dependent outer membrane protein, SusC/RagA (34.5%) TonB-dependent receptor, plug domain superfamily (31%)" TYQGAQPLHVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.3.- (75%) 3.6.3.28 (25%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (75%) Transferred entry: 7.3.2.2 (25%)" GO:0005886 (4.1%) "GO:0005524 (45.9%) GO:0016887 (45.9%) GO:0022857 (4.1%)" plasma membrane (4.1%) "ATP binding (45.9%) ATP hydrolysis activity (45.9%) transmembrane transporter activity (4.1%)" "IPR003439 (19.8%) IPR003593 (19.8%) IPR017871 (19.8%)" "ABC transporter-like, ATP-binding domain (19.8%) AAA+ ATPase domain (19.8%) ABC transporter-like, conserved site (19.8%)" RLAEGATMLR root 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (24.9%) GO:0008615 (24.9%) GO:0042823 (24.9%)" "GO:0036381 (23.3%) GO:0016843 (1.6%) GO:0016829 (0.2%)" "amino acid metabolic process (24.9%) pyridoxine biosynthetic process (24.9%) pyridoxal phosphate biosynthetic process (24.9%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (23.3%) amine-lyase activity (1.6%) lyase activity (0.2%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" LAASSEYENYEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.1.1.3 (50.7%) 2.7.2.4 (49.3%)" "homoserine dehydrogenase (50.7%) aspartate kinase (49.3%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" RLELALEGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" YSDAEALYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051596 (50%) GO:0016491 (50%) methylglyoxal catabolic process (50%) oxidoreductase activity (50%) "IPR005399 (33.9%) IPR023210 (33.9%) IPR036812 (32.2%)" "Potassium channel, voltage-dependent, beta subunit, KCNAB-related (33.9%) NADP-dependent oxidoreductase domain (33.9%) NAD(P)-dependent oxidoreductase domain superfamily (32.2%)" LPLSLAYEWGEFTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR008160 (50%) IPR032149 (50%)" "Collagen triple helix repeat (50%) Domain of unknown function DUF4988 (50%)" DDLASFLPAYMEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (97.3%) 2.7.-.- (2.7%)" "pyruvate, phosphate dikinase (97.3%) Transferring phosphorus-containing groups (2.7%)" "GO:0050242 (25.5%) GO:0005524 (24.8%) GO:0016301 (24.8%)" "pyruvate, phosphate dikinase activity (25.5%) ATP binding (24.8%) kinase activity (24.8%)" "IPR000121 (10.1%) IPR010121 (10.1%) IPR015813 (10.1%)" "PEP-utilising enzyme, C-terminal (10.1%) Pyruvate, phosphate dikinase (10.1%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.1%)" VLLDNFYYNFAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.3.- (100%) Acting on acid anhydrides; catalyzing transmembrane movement of substances (100%) "GO:0006412 (12.4%) GO:0006417 (12.4%)" GO:0005737 (12.4%) "GO:0003677 (12.7%) GO:0005524 (12.7%) GO:0016887 (12.7%)" "translation (12.4%) regulation of translation (12.4%)" cytoplasm (12.4%) "DNA binding (12.7%) ATP binding (12.7%) ATP hydrolysis activity (12.7%)" "IPR003439 (12.8%) IPR003593 (12.8%) IPR032524 (12.8%)" "ABC transporter-like, ATP-binding domain (12.8%) AAA+ ATPase domain (12.8%) ABC transporter Uup, C-terminal (12.8%)" MYPVPDDVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.4.1.1 (54.5%) 2.1.3.1 (45.5%)" "pyruvate carboxylase (54.5%) methylmalonyl-CoA carboxytransferase (45.5%)" GO:0006094 (32.8%) GO:0005737 (32.8%) "GO:0004736 (32.8%) GO:0047154 (1.1%) GO:0016740 (0.6%)" gluconeogenesis (32.8%) cytoplasm (32.8%) "pyruvate carboxylase activity (32.8%) methylmalonyl-CoA carboxytransferase activity (1.1%) transferase activity (0.6%)" "IPR000891 (20.8%) IPR003379 (20.8%) IPR055268 (20.8%)" "Pyruvate carboxyltransferase (20.8%) Carboxylase, conserved domain (20.8%) Pyruvate carboxylase-like (20.8%)" LGEFAPTR root 3.6.1.22 (100%) NAD(+) diphosphatase (100%) "GO:0006412 (16.8%) GO:0000028 (16.7%) GO:0032543 (0%)" "GO:0005737 (14.5%) GO:0015935 (14.5%) GO:0005763 (2.1%)" "GO:0003735 (16.8%) GO:0019843 (16%) GO:0003723 (0.8%)" "translation (16.8%) ribosomal small subunit assembly (16.7%) mitochondrial translation (0%)" "cytoplasm (14.5%) small ribosomal subunit (14.5%) mitochondrial small ribosomal subunit (2.1%)" "structural constituent of ribosome (16.8%) rRNA binding (16%) RNA binding (0.8%)" "IPR002222 (25.3%) IPR023575 (25.3%) IPR020934 (25.1%)" "Small ribosomal subunit protein uS19 (25.3%) Small ribosomal subunit protein uS19, superfamily (25.3%) Small ribosomal subunit protein uS19, conserved site (25.1%)" LMGWNTFGNVTLSDVKPAFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.2%) GO:0046556 (50.8%) L-arabinose metabolic process (49.2%) alpha-L-arabinofuranosidase activity (50.8%) "IPR003305 (17.5%) IPR051563 (17.5%) IPR010720 (17%)" "Carbohydrate-binding, CenC-like (17.5%) Glycosyl Hydrolase Family 51 (17.5%) Alpha-L-arabinofuranosidase, C-terminal (17%)" WGTFPAASLGFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" AADVETLGDLVQFNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) "GO:0000428 (16.9%) GO:0005737 (16%)" "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0046983 (16.4%)" DNA-templated transcription (16.8%) "DNA-directed RNA polymerase complex (16.9%) cytoplasm (16%)" "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) protein dimerization activity (16.4%)" "IPR011260 (17.2%) IPR011263 (16.8%) IPR036603 (16.7%)" "RNA polymerase, alpha subunit, C-terminal (17.2%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.8%) RNA polymerase, RBP11-like subunit (16.7%)" AAGFYPNKYPGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VTVLHADDLQAENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (16.9%) IPR010720 (16.9%) IPR051563 (16.9%)" "Carbohydrate-binding, CenC-like (16.9%) Alpha-L-arabinofuranosidase, C-terminal (16.9%) Glycosyl Hydrolase Family 51 (16.9%)" QVVEEFENEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.7%)" "GO:0003899 (16.7%) GO:0046983 (16.7%) GO:0003677 (16.5%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.7%)" "DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%) DNA binding (16.5%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR036603 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) RNA polymerase, RBP11-like subunit (16.7%)" LLGAPPGYVGYDEGGQLTEAVR root 3.4.21.92 (100%) endopeptidase Clp (100%) "GO:0034605 (19.1%) GO:0042026 (16.6%) GO:0006508 (3.2%)" "GO:0005737 (19.1%) GO:0005829 (0%)" "GO:0005524 (19.2%) GO:0016887 (19.2%) GO:0008233 (3.2%)" "cellular response to heat (19.1%) protein refolding (16.6%) proteolysis (3.2%)" "cytoplasm (19.1%) cytosol (0%)" "ATP binding (19.2%) ATP hydrolysis activity (19.2%) peptidase activity (3.2%)" "IPR003959 (8.6%) IPR050130 (8.6%) IPR001270 (8.6%)" "ATPase, AAA-type, core (8.6%) ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.6%) ClpA/B family (8.6%)" VDAFAPAFVTEYAAAHPEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0002161 (14.3%) GO:0004822 (14.3%)" isoleucyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) aminoacyl-tRNA deacylase activity (14.3%) isoleucine-tRNA ligase activity (14.3%)" "IPR002300 (12.5%) IPR002301 (12.5%) IPR009008 (12.5%)" "Aminoacyl-tRNA synthetase, class Ia (12.5%) Isoleucine-tRNA ligase (12.5%) Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain (12.5%)" NPYSQSQAPLLEQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (48.4%) "GO:0016787 (50%) GO:0016798 (1.6%)" carbohydrate metabolic process (48.4%) "hydrolase activity (50%) hydrolase activity, acting on glycosyl bonds (1.6%)" "IPR012878 (17.2%) IPR049046 (17.2%) IPR049049 (17.2%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (17.2%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (17.2%)" SPAPPFTTSTLQQEAAR Bacteria Bacteria 5.6.2.1 (100%) DNA topoisomerase (100%) "GO:0006265 (24%) GO:0007059 (0.2%)" GO:0005694 (4.7%) "GO:0003677 (24%) GO:0003917 (24%) GO:0046872 (18.5%)" "DNA topological change (24%) chromosome segregation (0.2%)" chromosome (4.7%) "DNA binding (24%) DNA topoisomerase type I (single strand cut, ATP-independent) activity (24%) metal ion binding (18.5%)" "IPR000380 (7.2%) IPR013497 (7.2%) IPR003602 (7.1%)" "DNA topoisomerase, type IA (7.2%) DNA topoisomerase, type IA, central (7.2%) DNA topoisomerase, type IA, DNA-binding domain (7.1%)" YYVSENVAPEVYALRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" LAGDCVLGNGVLYSTSVVENAK Pseudomonadati Bacteria Pseudomonadati 2.3.1.129 (100%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (100%) "GO:0009245 (30.1%) GO:0008610 (4.8%)" GO:0016020 (30.1%) GO:0008780 (34.9%) "lipid A biosynthetic process (30.1%) lipid biosynthetic process (4.8%)" membrane (30.1%) acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity (34.9%) "IPR010137 (20.4%) IPR011004 (20.4%) IPR029098 (20.4%)" "Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (20.4%) Trimeric LpxA-like superfamily (20.4%) UDP N-acetylglucosamine O-acyltransferase, C-terminal (20.4%)" YGYVVPFAEGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.8 (100%) mannose-6-phosphate isomerase (100%) "GO:0009298 (26.3%) GO:0005976 (24.6%)" "GO:0004475 (26.3%) GO:0000166 (21.1%) GO:0004476 (1.8%)" "GDP-mannose biosynthetic process (26.3%) polysaccharide metabolic process (24.6%)" "mannose-1-phosphate guanylyltransferase (GTP) activity (26.3%) nucleotide binding (21.1%) mannose-6-phosphate isomerase activity (1.8%)" "IPR005835 (18.5%) IPR051161 (18.5%) IPR001538 (17.3%)" "Nucleotidyl transferase domain (18.5%) Mannose-6-phosphate isomerase type 2 (18.5%) Mannose-6-phosphate isomerase, type II, C-terminal (17.3%)" FYSPEELAELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20.2%) GO:0005737 (20.2%) "GO:0004815 (20.2%) GO:0005524 (20.2%) GO:0003676 (19.4%)" aspartyl-tRNA aminoacylation (20.2%) cytoplasm (20.2%) "aspartate-tRNA ligase activity (20.2%) ATP binding (20.2%) nucleic acid binding (19.4%)" "IPR004364 (9.5%) IPR002312 (9.1%) IPR004115 (9.1%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.5%) Aspartyl/Asparaginyl-tRNA synthetase, class IIb (9.1%) GAD-like domain superfamily (9.1%)" SLYKPFSTEELNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (75%) GO:0016740 (25%)" "glycosyltransferase activity (75%) transferase activity (25%)" "IPR000836 (27.3%) IPR017932 (25%) IPR029057 (25%)" "Phosphoribosyltransferase domain (27.3%) Glutamine amidotransferase type 2 domain (25%) Phosphoribosyltransferase-like (25%)" LPFKDVAAECGVSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0043200 (32%) GO:0006355 (0.4%)" "GO:0005829 (32%) GO:0016020 (0.2%)" "GO:0043565 (35.1%) GO:0003700 (0.2%)" "response to amino acid (32%) regulation of DNA-templated transcription (0.4%)" "cytosol (32%) membrane (0.2%)" "sequence-specific DNA binding (35.1%) DNA-binding transcription factor activity (0.2%)" "IPR000485 (16.5%) IPR036388 (16.5%) IPR036390 (16.5%)" "AsnC-type HTH domain (16.5%) Winged helix-like DNA-binding domain superfamily (16.5%) Winged helix DNA-binding domain superfamily (16.5%)" AYFGEKDWQQLAVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.2.1 (100%) pantoate--beta-alanine ligase (AMP-forming) (100%) GO:0015940 (25%) GO:0005829 (25%) "GO:0004592 (25%) GO:0005524 (25%)" pantothenate biosynthetic process (25%) cytosol (25%) "pantoate-beta-alanine ligase activity (25%) ATP binding (25%)" "IPR003721 (33.2%) IPR014729 (33.2%) IPR042176 (33.2%)" "Pantoate-beta-alanine ligase (33.2%) Rossmann-like alpha/beta/alpha sandwich fold (33.2%) Pantoate-beta-alanine ligase, C-terminal domain (33.2%)" AVDEMAEQASFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) GO:0033362 (33.3%) "GO:0010285 (33.3%) GO:0030170 (33.3%)" lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (33.3%) "L,L-diaminopimelate aminotransferase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (21%) IPR019942 (21%) IPR015421 (19.4%)" "Aminotransferase, class I/classII, large domain (21%) LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21%) Pyridoxal phosphate-dependent transferase, major domain (19.4%)" NDFEAYNDVTLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.9 (100%) valine--tRNA ligase (100%) GO:0006438 (20.2%) GO:0005829 (20.2%) "GO:0004832 (20.2%) GO:0005524 (20.2%) GO:0002161 (19.1%)" valyl-tRNA aminoacylation (20.2%) cytosol (20.2%) "valine-tRNA ligase activity (20.2%) ATP binding (20.2%) aminoacyl-tRNA deacylase activity (19.1%)" "IPR001412 (9.3%) IPR002300 (9.3%) IPR002303 (9.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (9.3%) Aminoacyl-tRNA synthetase, class Ia (9.3%) Valine-tRNA ligase (9.3%)" FWGTPLPLWR root "6.1.1.5 (99.7%) 6.1.1.- (0.3%)" "isoleucine--tRNA ligase (99.7%) Ligases forming aminoacyl-tRNA and related compounds (0.3%)" "GO:0006428 (14.4%) GO:0009791 (0.4%) GO:0048608 (0.4%)" GO:0005737 (13.8%) "GO:0004822 (14.4%) GO:0005524 (14.4%) GO:0000049 (14.4%)" "isoleucyl-tRNA aminoacylation (14.4%) post-embryonic development (0.4%) reproductive structure development (0.4%)" cytoplasm (13.8%) "isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%) tRNA binding (14.4%)" "IPR002300 (12.5%) IPR023586 (12.5%) IPR002301 (12.4%)" "Aminoacyl-tRNA synthetase, class Ia (12.5%) Isoleucine-tRNA ligase, type 2 (12.5%) Isoleucine-tRNA ligase (12.4%)" GLLKPGATLLEPTSGNTGVGLALVSAVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.47 (100%) cysteine synthase (100%) GO:0006535 (45.2%) GO:0005737 (9.7%) "GO:0004124 (44.4%) GO:0016846 (0.8%)" cysteine biosynthetic process from serine (45.2%) cytoplasm (9.7%) "cysteine synthase activity (44.4%) carbon-sulfur lyase activity (0.8%)" "IPR001216 (16.9%) IPR001926 (16.9%) IPR050214 (16.9%)" "Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site (16.9%) Tryptophan synthase beta chain-like, PALP domain (16.9%) Cysteine synthase/Cystathionine beta-synthase (16.9%)" VFPAGNVGGPSFVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "4.1.2.14 (51.7%) 4.1.3.16 (45%) 4.1.3.42 (3.3%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (51.7%) 4-hydroxy-2-oxoglutarate aldolase (45%) (4S)-4-hydroxy-2-oxoglutarate aldolase (3.3%)" "GO:0016829 (75.3%) GO:0008675 (13.7%) GO:0008700 (11%)" "lyase activity (75.3%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (13.7%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (11%)" "IPR000887 (50.4%) IPR013785 (49.6%)" "KDPG/KHG aldolase (50.4%) Aldolase-type TIM barrel (49.6%)" TDAEGYYGLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.92 (100%) 5-dehydro-2-deoxygluconokinase (100%) "GO:0016301 (96%) GO:0047590 (4%)" "kinase activity (96%) 5-dehydro-2-deoxygluconokinase activity (4%)" "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" TLLTNVGNVDSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12%) IPR012910 (12%) IPR023996 (12%)" "TonB-dependent receptor-like, beta-barrel (12%) TonB-dependent receptor, plug domain (12%) TonB-dependent outer membrane protein, SusC/RagA (12%)" LVGVPSSPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.24 (100%) phosphoribosylanthranilate isomerase (100%) "GO:0006412 (23.3%) GO:0000162 (3.3%)" GO:0022625 (23.3%) "GO:0003735 (23.3%) GO:0019843 (23.3%) GO:0004640 (3.3%)" "translation (23.3%) L-tryptophan biosynthetic process (3.3%)" cytosolic large ribosomal subunit (23.3%) "structural constituent of ribosome (23.3%) rRNA binding (23.3%) phosphoribosylanthranilate isomerase activity (3.3%)" "IPR001063 (20.6%) IPR005727 (20.6%) IPR036394 (20.6%)" "Large ribosomal subunit protein uL22 (20.6%) Large ribosomal subunit protein uL22, bacterial/chloroplast-type (20.6%) Ribosomal protein uL22 superfamily (20.6%)" LLTLEDGVR root "2.2.1.7 (91.1%) 3.2.1.35 (3.6%) 3.6.4.13 (3.6%)" "1-deoxy-D-xylulose-5-phosphate synthase (91.1%) hyaluronoglucosaminidase (3.6%) RNA helicase (3.6%)" "GO:0009228 (12.1%) GO:0016114 (12.1%) GO:0019288 (12.1%)" "GO:0005829 (12.3%) GO:0005576 (0.5%) GO:0005682 (0.5%)" "GO:0000287 (12.1%) GO:0008661 (12.1%) GO:0030976 (12.1%)" "thiamine biosynthetic process (12.1%) terpenoid biosynthetic process (12.1%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (12.1%)" "cytosol (12.3%) extracellular region (0.5%) U5 snRNP (0.5%)" "magnesium ion binding (12.1%) 1-deoxy-D-xylulose-5-phosphate synthase activity (12.1%) thiamine pyrophosphate binding (12.1%)" "IPR005475 (13.8%) IPR005477 (13.8%) IPR033248 (13.8%)" "Transketolase-like, pyrimidine-binding domain (13.8%) Deoxyxylulose-5-phosphate synthase (13.8%) Transketolase, C-terminal domain (13.8%)" YVVLSAPSKADANGNQADMFVCGVNTDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (18.8%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (18.8%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" DAAQLLSR root "5.4.99.25 (12.5%) 1.2.4.1 (6.3%) 2.1.2.10 (6.3%)" "tRNA pseudouridine(55) synthase (12.5%) pyruvate dehydrogenase (acetyl-transferring) (6.3%) aminomethyltransferase (6.3%)" "GO:0046856 (10.1%) GO:0005975 (1.6%) GO:0031119 (1.6%)" "GO:0005886 (4.8%) GO:0016020 (3.7%) GO:0005741 (2.6%)" "GO:0004439 (10.1%) GO:0005524 (7.4%) GO:0016887 (6.3%)" "phosphatidylinositol dephosphorylation (10.1%) carbohydrate metabolic process (1.6%) tRNA pseudouridine synthesis (1.6%)" "plasma membrane (4.8%) membrane (3.7%) mitochondrial outer membrane (2.6%)" "phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity (10.1%) ATP binding (7.4%) ATP hydrolysis activity (6.3%)" "IPR025964 (56.3%) IPR000300 (2.1%) IPR013783 (2.1%)" "GGGtGRT protein (56.3%) Inositol polyphosphate-related phosphatase (2.1%) Immunoglobulin-like fold (2.1%)" ELNYRPNPFAQSLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25.2%) IPR010982 (24.3%) IPR028082 (24.3%)" "LacI-type HTH domain (25.2%) Lambda repressor-like, DNA-binding domain superfamily (24.3%) Periplasmic binding protein-like I (24.3%)" AAVEALQPLLDTVGGLDKLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016301 (100%) kinase activity (100%) "IPR000600 (35%) IPR049874 (33.3%) IPR043129 (31.7%)" "ROK family (35%) ROK, conserved site (33.3%) ATPase, nucleotide binding domain (31.7%)" YLVMDENSK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.4%) GO:0005829 (17.4%) "GO:0004612 (17.4%) GO:0005524 (17.4%) GO:0046872 (17.3%)" gluconeogenesis (17.4%) cytosol (17.4%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.4%) ATP binding (17.4%) metal ion binding (17.3%)" "IPR001272 (25.1%) IPR008210 (25.1%) IPR013035 (24.9%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.1%) Phosphoenolpyruvate carboxykinase, N-terminal (25.1%) Phosphoenolpyruvate carboxykinase, C-terminal (24.9%)" SDKADAEVLDAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (47.8%) GO:0033711 (2.2%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (47.8%) 4-phosphoerythronate dehydrogenase activity (2.2%)" "IPR006139 (31.1%) IPR006140 (31.1%) IPR036291 (31.1%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (31.1%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (31.1%) NAD(P)-binding domain superfamily (31.1%)" LGADTGFDSLGEFTTAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (51%) IPR032466 (49%)" "Uronate isomerase (51%) Metal-dependent hydrolase (49%)" TTLVSVLEESFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006353 (19.7%) GO:0031564 (19.7%)" GO:0005829 (19.7%) "GO:0003700 (19.7%) GO:0003723 (19.7%) GO:0003746 (1.4%)" "DNA-templated transcription termination (19.7%) transcription antitermination (19.7%)" cytosol (19.7%) "DNA-binding transcription factor activity (19.7%) RNA binding (19.7%) translation elongation factor activity (1.4%)" "IPR010213 (11.4%) IPR013735 (11.4%) IPR025249 (11.4%)" "Transcription factor NusA (11.4%) Transcription factor NusA, N-terminal (11.4%) Transcription factor NusA, first KH domain (11.4%)" YLEGGALQDTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0016491 (47.4%) GO:0016692 (2.6%)" "iron ion binding (50%) oxidoreductase activity (47.4%) NADH peroxidase activity (2.6%)" "IPR003251 (14.5%) IPR009040 (14.5%) IPR024934 (14.5%)" "Rubrerythrin, diiron-binding domain (14.5%) Ferritin-like diiron domain (14.5%) Rubredoxin-like domain (14.5%)" KNTSYELFYNALDLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (20%) GO:0015935 (20%) "GO:0000049 (20%) GO:0003735 (20%) GO:0019843 (20%)" translation (20%) small ribosomal subunit (20%) "tRNA binding (20%) structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" AFSQVAPDDLESLSVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" NGLPEFDDYNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR011990 (32.9%) IPR033985 (32.9%)" "RagB/SusD domain (34.2%) Tetratricopeptide-like helical domain superfamily (32.9%) SusD-like, N-terminal (32.9%)" NSVGAPENRPLNENR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" GVPDWVGGMTNTFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" LLFEVEGVSFDLAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.1%) GO:0022625 (20.1%) "GO:0003735 (20.1%) GO:0019843 (20.1%) GO:0000049 (19.6%)" translation (20.1%) cytosolic large ribosomal subunit (20.1%) "structural constituent of ribosome (20.1%) rRNA binding (20.1%) tRNA binding (19.6%)" "IPR000114 (20%) IPR016180 (20%) IPR020798 (20%)" "Large ribosomal subunit protein uL16, bacteria (20%) Large ribosomal subunit protein uL16 domain (20%) Large ribosomal subunit protein uL16, conserved site (20%)" LPNGESFMEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (33.3%) GO:0005737 (33.3%) GO:0008734 (33.3%) 'de novo' NAD+ biosynthetic process from L-aspartate (33.3%) cytoplasm (33.3%) L-aspartate oxidase activity (33.3%) "IPR003953 (16.9%) IPR005288 (16.9%) IPR015939 (16.9%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (16.9%) L-aspartate oxidase (16.9%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (16.9%)" VLYLTAK root "3.2.1.23 (40.5%) 2.3.2.13 (37.8%) 2.7.1.71 (8.1%)" "beta-galactosidase (40.5%) protein-glutamine gamma-glutamyltransferase (37.8%) shikimate kinase (8.1%)" "GO:0006355 (9.4%) GO:0000272 (1.2%) GO:0005990 (1%)" "GO:0005829 (10.1%) GO:0032993 (9.4%) GO:0005886 (3.2%)" "GO:0000156 (9.4%) GO:0000976 (9.3%) GO:0005524 (1.6%)" "regulation of DNA-templated transcription (9.4%) polysaccharide catabolic process (1.2%) lactose catabolic process (1%)" "cytosol (10.1%) protein-DNA complex (9.4%) plasma membrane (3.2%)" "phosphorelay response regulator activity (9.4%) transcription cis-regulatory region binding (9.3%) ATP binding (1.6%)" "IPR001789 (7.1%) IPR011006 (7%) IPR036388 (6.9%)" "Signal transduction response regulator, receiver domain (7.1%) CheY-like superfamily (7%) Winged helix-like DNA-binding domain superfamily (6.9%)" VWNNTFWGQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016787 (50%) carbohydrate metabolic process (50%) hydrolase activity (50%) "IPR012878 (16.8%) IPR049046 (16.8%) IPR049049 (16.8%)" "Non-reducing end beta-L-arabinofuranosidase-like, GH127 catalytic domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 middle domain (16.8%) Non-reducing end beta-L-arabinofuranosidase-like, GH127 C-terminal domain (16.8%)" VTWPLVSK Pseudomonadati Bacteria Pseudomonadati GO:0006974 (61.9%) GO:0016020 (38.1%) DNA damage response (61.9%) membrane (38.1%) "IPR007497 (32.9%) IPR052022 (32.9%) IPR016907 (31.6%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (32.9%) 26 kDa periplasmic antigen-related (32.9%) Uncharacterised conserved protein UCP029033, periplasmic protein (31.6%)" LNDLEALAMSYPGVTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.9%) GO:0005886 (20%) "GO:0003723 (20%) GO:0016787 (20%) GO:0004521 (19.9%)" mRNA catabolic process (19.9%) plasma membrane (20%) "RNA binding (20%) hydrolase activity (20%) RNA endonuclease activity (19.9%)" "IPR006674 (12.6%) IPR006675 (12.6%) IPR003607 (12.5%)" "HD domain (12.6%) HDIG domain (12.6%) HD/PDEase domain (12.5%)" EENLDPTEPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.4%) IPR002942 (11.4%) IPR006145 (11.4%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.4%) RNA-binding S4 domain (11.4%) Pseudouridine synthase, RsuA/RluA-like (11.4%)" WNQLSNDYYFGNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" QFNYSSAMELPVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" FDFSVLGGPHYASDTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0019867 (100%) outer membrane (100%) "IPR000184 (77.8%) IPR036709 (22.2%)" "Bacterial surface antigen (D15) (77.8%) Autotransporter beta-domain superfamily (22.2%)" LTDSFSVPVFAQVAANPSTEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella VFELVLR root "2.1.1.221 (27.2%) 3.2.1.- (20.7%) 2.1.1.72 (14.1%)" "tRNA (guanine(9)-N(1))-methyltransferase (27.2%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (20.7%) site-specific DNA-methyltransferase (adenine-specific) (14.1%)" "GO:0005975 (5.9%) GO:0022904 (3.8%) GO:0002939 (1.7%)" "GO:0016020 (3.9%) GO:0005737 (2.5%) GO:0005615 (1.8%)" "GO:0016787 (11.5%) GO:0005524 (6.9%) GO:0004386 (5%)" "carbohydrate metabolic process (5.9%) respiratory electron transport chain (3.8%) tRNA N1-guanine methylation (1.7%)" "membrane (3.9%) cytoplasm (2.5%) extracellular space (1.8%)" "hydrolase activity (11.5%) ATP binding (6.9%) helicase activity (5%)" "IPR027417 (4.3%) IPR014001 (3.7%) IPR001650 (3.7%)" "P-loop containing nucleoside triphosphate hydrolase (4.3%) Helicase superfamily 1/2, ATP-binding domain (3.7%) Helicase, C-terminal domain-like (3.7%)" APLEGDVLTDAKDEFDQMGSPVVSMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (19.7%) GO:0043952 (19.7%) GO:0065002 (19.7%)" GO:0005886 (20.2%) GO:0015450 (20.2%) "protein targeting (19.7%) protein transport by the Sec complex (19.7%) intracellular protein transmembrane transport (19.7%)" plasma membrane (20.2%) protein-transporting ATPase activity (20.2%) "IPR005791 (11.3%) IPR022646 (11.3%) IPR022813 (11.3%)" "Protein translocase subunit SecD (11.3%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.3%) Protein-export membrane protein SecD/SecF, archaeal and bacterial (11.3%)" TGYMSLLK root "2.7.1.90 (95.2%) 2.1.1.266 (4.8%)" "diphosphate--fructose-6-phosphate 1-phosphotransferase (95.2%) 23S rRNA (adenine(2030)-N(6))-methyltransferase (4.8%)" "GO:0009749 (11.3%) GO:0006002 (9.5%) GO:0006888 (1.2%)" "GO:0005829 (11.9%) GO:0005634 (1.8%) GO:0030288 (1.2%)" "GO:0003872 (11.3%) GO:0005524 (11.3%) GO:0046872 (11.3%)" "response to glucose (11.3%) fructose 6-phosphate metabolic process (9.5%) endoplasmic reticulum to Golgi vesicle-mediated transport (1.2%)" "cytosol (11.9%) nucleus (1.8%) outer membrane-bounded periplasmic space (1.2%)" "6-phosphofructokinase activity (11.3%) ATP binding (11.3%) metal ion binding (11.3%)" "IPR000023 (20%) IPR011183 (20%) IPR035966 (18.9%)" "Phosphofructokinase domain (20%) Pyrophosphate-dependent phosphofructokinase PfpB (20%) Phosphofructokinase superfamily (18.9%)" SACNGCQFDVNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.6%) "GO:0009279 (26.3%) GO:0046930 (24.6%)" GO:0015288 (24.6%) monoatomic ion transport (24.6%) "cell outer membrane (26.3%) pore complex (24.6%)" porin activity (24.6%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" DHFNGECGEVGMYLAMAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (41.7%) GO:0016491 (8.3%)" "iron ion binding (50%) peroxidase activity (41.7%) oxidoreductase activity (8.3%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" AQMVDMLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (6.5%) GO:0009279 (87.1%) GO:0015344 (6.5%) siderophore transmembrane transport (6.5%) cell outer membrane (87.1%) siderophore uptake transmembrane transporter activity (6.5%) "IPR012910 (12.2%) IPR023997 (12.2%) IPR039426 (12.2%)" "TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.2%) TonB-dependent receptor-like (12.2%)" LTSANSLNVAR root "4.2.3.1 (99.9%) 4.3.1.17 (0.1%)" "threonine synthase (99.9%) L-serine ammonia-lyase (0.1%)" "GO:0009088 (33.8%) GO:0006520 (0%) GO:1901605 (0%)" GO:0016020 (0%) "GO:0004795 (34%) GO:0030170 (31.8%) GO:0016829 (0.2%)" "threonine biosynthetic process (33.8%) amino acid metabolic process (0%) alpha-amino acid metabolic process (0%)" membrane (0%) "threonine synthase activity (34%) pyridoxal phosphate binding (31.8%) lyase activity (0.2%)" "IPR051166 (14.5%) IPR001926 (14.5%) IPR036052 (14.4%)" "Threonine Synthase (14.5%) Tryptophan synthase beta chain-like, PALP domain (14.5%) Tryptophan synthase beta chain-like, PALP domain superfamily (14.4%)" DWCKDEGYDLYTSGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.3%) GO:0009252 (11.3%) GO:0071555 (11.3%)" "GO:0030288 (11.3%) GO:0005886 (10.5%) GO:0016020 (0.8%)" "GO:0008658 (11.3%) GO:0008955 (11.3%) GO:0004180 (10.5%)" "regulation of cell shape (11.3%) peptidoglycan biosynthetic process (11.3%) cell wall organization (11.3%)" "outer membrane-bounded periplasmic space (11.3%) plasma membrane (10.5%) membrane (0.8%)" "penicillin binding (11.3%) peptidoglycan glycosyltransferase activity (11.3%) carboxypeptidase activity (10.5%)" "IPR001264 (17.3%) IPR001460 (17.3%) IPR050396 (17.3%)" "Glycosyl transferase, family 51 (17.3%) Penicillin-binding protein, transpeptidase (17.3%) Glycosyltransferase 51/Transpeptidase (17.3%)" AVENNGANQFEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50.9%) IPR032317 (49.1%)" "RND efflux pump, membrane fusion protein (50.9%) Unknown (49.1%)" TVGEQLANQFSLGLAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20.9%) GO:0000428 (20.9%) "GO:0003677 (20.9%) GO:0003899 (20.9%) GO:0032549 (16.6%)" DNA-templated transcription (20.9%) DNA-directed RNA polymerase complex (20.9%) "DNA binding (20.9%) DNA-directed RNA polymerase activity (20.9%) ribonucleoside binding (16.6%)" "IPR007645 (10.3%) IPR007642 (8.2%) IPR015712 (8.2%)" "RNA polymerase Rpb2, domain 3 (10.3%) RNA polymerase Rpb2, domain 2 (8.2%) DNA-directed RNA polymerase, subunit 2 (8.2%)" LFEAGFSTNMSMSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" VETTDQFVAQTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" DGGVALMSTGYGEGEGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000917 (14.2%) GO:0043093 (14.2%) GO:0051258 (14.2%)" "GO:0005737 (14.3%) GO:0032153 (14.3%)" "GO:0003924 (14.3%) GO:0005525 (14.3%)" "division septum assembly (14.2%) FtsZ-dependent cytokinesis (14.2%) protein polymerization (14.2%)" "cytoplasm (14.3%) cell division site (14.3%)" "GTPase activity (14.3%) GTP binding (14.3%)" "IPR000158 (11.4%) IPR003008 (11.4%) IPR018316 (11.4%)" "Cell division protein FtsZ (11.4%) Tubulin/FtsZ, GTPase domain (11.4%) Tubulin/FtsZ, 2-layer sandwich domain (11.4%)" NSTYFVEDGSYLR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (12.8%) IPR039426 (12.8%) IPR012910 (12.6%)" "TonB-dependent outer membrane protein, SusC/RagA (12.8%) TonB-dependent receptor-like (12.8%) TonB-dependent receptor, plug domain (12.6%)" KNVDALDGEAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" EGVASMTAVLQDEMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" YVVVVNPGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009313 (49.3%) "GO:0004556 (49.3%) GO:0016301 (1.4%)" oligosaccharide catabolic process (49.3%) "alpha-amylase activity (49.3%) kinase activity (1.4%)" "IPR006047 (26%) IPR013780 (25.2%) IPR017853 (24.4%)" "Glycosyl hydrolase family 13, catalytic domain (26%) Glycosyl hydrolase, all-beta (25.2%) Glycoside hydrolase superfamily (24.4%)" VMNELQDMDESHYYMLTQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) FAMNAEVGASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" AEVDETTGLEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" RDLTCANFELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DAVSATSTQLLQGLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (17.1%) GO:0000428 (17.1%) "GO:0003677 (17.1%) GO:0003899 (17.1%) GO:0000287 (15.7%)" DNA-templated transcription (17.1%) DNA-directed RNA polymerase complex (17.1%) "DNA binding (17.1%) DNA-directed RNA polymerase activity (17.1%) magnesium ion binding (15.7%)" "IPR007081 (10%) IPR045867 (10%) IPR000722 (9.2%)" "RNA polymerase Rpb1, domain 5 (10%) DNA-directed RNA polymerase, subunit beta-prime (10%) RNA polymerase, alpha subunit (9.2%)" KLAGLTNMSNYTNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (35.5%) "GO:0004556 (32.3%) GO:0043169 (32.3%)" carbohydrate metabolic process (35.5%) "alpha-amylase activity (32.3%) cation binding (32.3%)" "IPR006047 (35.5%) IPR006046 (32.3%) IPR017853 (32.3%)" "Glycosyl hydrolase family 13, catalytic domain (35.5%) Alpha amylase (32.3%) Glycoside hydrolase superfamily (32.3%)" QDLTQVYVGVGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0043093 (33.3%) "GO:0009898 (33.3%) GO:0032153 (33.3%)" FtsZ-dependent cytokinesis (33.3%) "cytoplasmic side of plasma membrane (33.3%) cell division site (33.3%)" "IPR003494 (25%) IPR020823 (25%) IPR043129 (25%)" "SHS2 domain inserted in FtsA (25%) Cell division protein FtsA (25%) ATPase, nucleotide binding domain (25%)" EQGSDALHDTVHEMAKDEAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.11.1.1 (100%) NADH peroxidase (100%) "GO:0005506 (50%) GO:0004601 (40.6%) GO:0016491 (9.4%)" "iron ion binding (50%) peroxidase activity (40.6%) oxidoreductase activity (9.4%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" LGLTVTDAELQDLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (27.6%) IPR027304 (26.7%) IPR046357 (26.7%)" "Periplasmic chaperone PpiD (27.6%) Trigger factor/SurA domain superfamily (26.7%) Peptidyl-prolyl cis-trans isomerase domain superfamily (26.7%)" LLASEVECLEPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.3%) GO:0005829 (25.3%) "GO:0008733 (25.3%) GO:0030145 (24.1%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.3%) cytosol (25.3%) "L-arabinose isomerase activity (25.3%) manganese ion binding (24.1%)" "IPR003762 (14.8%) IPR024664 (14.8%) IPR055390 (14.8%)" "L-arabinose isomerase (14.8%) L-arabinose isomerase, C-terminal (14.8%) L-arabinose isomerase, central domain (14.8%)" THLFDDVLYLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (15.4%) GO:0006261 (9.5%) GO:0032259 (0.1%)" "GO:0005737 (9.6%) GO:0005694 (9.5%)" "GO:0003677 (15.4%) GO:0005524 (15.4%) GO:0034335 (9.5%)" "DNA topological change (15.4%) DNA-templated DNA replication (9.5%) methylation (0.1%)" "cytoplasm (9.6%) chromosome (9.5%)" "DNA binding (15.4%) ATP binding (15.4%) DNA negative supercoiling activity (9.5%)" "IPR001241 (8.5%) IPR006171 (8.5%) IPR013506 (8.5%)" "DNA topoisomerase, type IIA (8.5%) TOPRIM domain (8.5%) DNA topoisomerase, type IIA, subunit B, domain 2 (8.5%)" QLNAFFK root "1.1.1.290 (30%) 1.1.1.95 (30%) 2.7.1.11 (20%)" "4-phosphoerythronate dehydrogenase (30%) phosphoglycerate dehydrogenase (30%) 6-phosphofructokinase (20%)" "GO:0000462 (2.3%) GO:0006002 (0.8%) GO:0000272 (0.4%)" "GO:0016020 (9.4%) GO:0009505 (3%) GO:0005576 (2.3%)" "GO:0051287 (16.6%) GO:0016616 (14.3%) GO:0004497 (6.8%)" "maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (2.3%) fructose 6-phosphate metabolic process (0.8%) polysaccharide catabolic process (0.4%)" "membrane (9.4%) plant-type cell wall (3%) extracellular region (2.3%)" "NAD binding (16.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (14.3%) monooxygenase activity (6.8%)" "IPR006140 (11.1%) IPR036291 (11.1%) IPR006139 (10.8%)" "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (11.1%) NAD(P)-binding domain superfamily (11.1%) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (10.8%)" DLYELWDNLNPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.5%) GO:0008295 (19.5%) GO:0033388 (19.5%)" "GO:0008792 (19.5%) GO:0046872 (19.5%) GO:0004497 (2.5%)" "L-arginine catabolic process (19.5%) spermidine biosynthetic process (19.5%) putrescine biosynthetic process from arginine (19.5%)" "arginine decarboxylase activity (19.5%) metal ion binding (19.5%) monooxygenase activity (2.5%)" "IPR002985 (11.2%) IPR022644 (11.2%) IPR022653 (11.2%)" "Arginine decarboxylase (11.2%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.2%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.2%)" NLTCLFVDHGMLR Bacteria Bacteria 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0006177 (0.1%) GO:0005829 (33.3%) "GO:0003921 (33.3%) GO:0005524 (33.3%) GO:0016740 (0.1%)" GMP biosynthetic process (0.1%) cytosol (33.3%) "GMP synthase activity (33.3%) ATP binding (33.3%) transferase activity (0.1%)" "IPR025777 (12.6%) IPR017926 (12.6%) IPR022310 (12.6%)" "GMP synthetase ATP pyrophosphatase domain (12.6%) Glutamine amidotransferase (12.6%) NAD/GMP synthase (12.6%)" AVNGGQAPLYADPYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SVTLNSDFSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ANAVAPGFLETAMTAQLPEELR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) GO:0006633 (33.3%) "GO:0004316 (30%) GO:0051287 (30%) GO:0016616 (3.3%)" fatty acid biosynthetic process (33.3%) "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (30%) NAD binding (30%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (3.3%)" "IPR002347 (17.9%) IPR020904 (17.9%) IPR011284 (16.1%)" "Short-chain dehydrogenase/reductase SDR (17.9%) Short-chain dehydrogenase/reductase, conserved site (17.9%) 3-oxoacyl-(acyl-carrier-protein) reductase (16.1%)" LAYDHFSNLYENYSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" TSTFNVGSVQNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" LPEGPVAEK Pseudomonadati Bacteria Pseudomonadati 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (15.7%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (15.7%)" "IPR003953 (14.5%) IPR030664 (14.5%) IPR036188 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.5%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.5%) FAD/NAD(P)-binding domain superfamily (14.4%)" LFALQDLLVEKEYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (33.3%) IPR039565 (33.3%) IPR011990 (31.5%)" "Outer membrane protein assembly factor BamD (33.3%) Outer membrane lipoprotein BamD-like (33.3%) Tetratricopeptide-like helical domain superfamily (31.5%)" NVLPSSDLK root 3.1.1.11 (100%) pectinesterase (100%) "GO:0006412 (20.6%) GO:0042545 (4.2%) GO:0045490 (3.2%)" "GO:0022625 (20.6%) GO:0005576 (3.2%) GO:0016020 (1.3%)" "GO:0003735 (20.6%) GO:0070180 (20.6%) GO:0030599 (4.2%)" "translation (20.6%) cell wall modification (4.2%) pectin catabolic process (3.2%)" "cytosolic large ribosomal subunit (20.6%) extracellular region (3.2%) membrane (1.3%)" "structural constituent of ribosome (20.6%) large ribosomal subunit rRNA binding (20.6%) pectinesterase activity (4.2%)" "IPR000218 (20.4%) IPR005745 (20.4%) IPR036853 (20.4%)" "Large ribosomal subunit protein uL14 (20.4%) Large ribosomal subunit protein uL14, bacteria (20.4%) Large ribosomal subunit protein uL14 superfamily (20.4%)" APFFMYGEVCTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (70.3%) "GO:0016787 (21.6%) GO:0016829 (8.1%)" carbohydrate metabolic process (70.3%) "hydrolase activity (21.6%) lyase activity (8.1%)" "IPR013783 (24.3%) IPR017853 (24.3%) IPR031965 (24.3%)" "Immunoglobulin-like fold (24.3%) Glycoside hydrolase superfamily (24.3%) Starch-binding module 26 (24.3%)" LAETALTTGNLGYAVNSFTQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (92.3%) GO:0015344 (7.7%) cell outer membrane (92.3%) siderophore uptake transmembrane transporter activity (7.7%) "IPR036942 (92.3%) IPR039426 (7.7%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (92.3%) TonB-dependent receptor-like (7.7%)" VDEVANNWFLGEPLNVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" NYQNDGDSVYR root "1.3.5.1 (99%) 1.3.5.4 (1%)" "succinate dehydrogenase (99%) Transferred entry: 1.3.5.1 (1%)" "GO:0009061 (20%) GO:0006633 (0%)" "GO:0005886 (20%) GO:0009317 (0%)" "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (14.9%)" "anaerobic respiration (20%) fatty acid biosynthetic process (0%)" "plasma membrane (20%) acetyl-CoA carboxylase complex (0%)" "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (14.9%)" "IPR003953 (14.4%) IPR030664 (14.4%) IPR036188 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) FAD/NAD(P)-binding domain superfamily (14.4%)" TLNPGENLTGPLNGASFVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" MNMDMLLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" NSADVLADEVLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.1%) GO:0008360 (12.1%) GO:0009252 (12.1%)" GO:0005886 (12.1%) "GO:0050511 (12.1%) GO:0051991 (3.4%)" "carbohydrate metabolic process (12.1%) regulation of cell shape (12.1%) peptidoglycan biosynthetic process (12.1%)" plasma membrane (12.1%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.1%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (3.4%)" "IPR004276 (33.3%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.3%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" ALEAYPGRVEDEGL Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.6.1.- (50%) 2.6.1.1 (50%)" "Transaminases (50%) aspartate transaminase (50%)" GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (21.1%) IPR050596 (21.1%) IPR015421 (19.3%)" "Aminotransferase, class I/classII, large domain (21.1%) Aspartate/prephenate aminotransferase-like (21.1%) Pyridoxal phosphate-dependent transferase, major domain (19.3%)" ALDETEKPQVGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (25%) GO:0005576 (25%) "GO:0033939 (25%) GO:0046559 (25%)" xylan catabolic process (25%) extracellular region (25%) "xylan alpha-1,2-glucuronosidase activity (25%) alpha-glucuronidase activity (25%)" "IPR011099 (20.8%) IPR011100 (20.8%) IPR017853 (19.5%)" "Glycosyl hydrolase family 67, C-terminal (20.8%) Glycosyl hydrolase family 67, catalytic domain (20.8%) Glycoside hydrolase superfamily (19.5%)" MNTPEAVEGSMVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.18 (100%) glutamine--tRNA ligase (100%) GO:0006425 (25%) GO:0005829 (25%) "GO:0004819 (25%) GO:0005524 (25%)" glutaminyl-tRNA aminoacylation (25%) cytosol (25%) "glutamine-tRNA ligase activity (25%) ATP binding (25%)" "IPR020058 (10.9%) IPR050132 (10.9%) IPR004514 (10.7%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.9%) Glutamine/Glutamate--tRNA Ligase (10.9%) Glutamine-tRNA synthetase (10.7%)" RVQLQNAGDFDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" KADGSLEPLPMHVLDTGMGFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.7 (100%) alanine--tRNA ligase (100%) GO:0006419 (14.4%) GO:0005737 (14.1%) "GO:0000049 (14.4%) GO:0002161 (14.4%) GO:0004813 (14.4%)" alanyl-tRNA aminoacylation (14.4%) cytoplasm (14.1%) "tRNA binding (14.4%) aminoacyl-tRNA deacylase activity (14.4%) alanine-tRNA ligase activity (14.4%)" "IPR018164 (9.4%) IPR018165 (9.4%) IPR050058 (9.4%)" "Alanyl-tRNA synthetase, class IIc, N-terminal (9.4%) Alanyl-tRNA synthetase, class IIc, core domain (9.4%) Alanine--tRNA ligase (9.4%)" VAFLPTASLR Bacteria Bacteria "3.4.21.- (68.4%) 3.4.13.21 (31.6%)" "Serine endopeptidases (68.4%) dipeptidase E (31.6%)" GO:0006508 (47.9%) "GO:0008236 (47.9%) GO:0016740 (2.4%) GO:0016805 (1.8%)" proteolysis (47.9%) "serine-type peptidase activity (47.9%) transferase activity (2.4%) dipeptidase activity (1.8%)" "IPR005320 (50.2%) IPR029062 (49.8%)" "Peptidase S51 (50.2%) Class I glutamine amidotransferase-like (49.8%)" VNPALLMAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (25.8%) IPR012131 (25.8%) IPR016161 (24.2%)" "Histidinol dehydrogenase, conserved site (25.8%) Histidinol dehydrogenase (25.8%) Aldehyde/histidinol dehydrogenase (24.2%)" SEDVFNPFSLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005524 (100%) ATP binding (100%) "IPR018631 (38.8%) IPR012547 (31.2%) IPR027417 (30%)" "AAA-ATPase-like domain (38.8%) PD-(D/E)XK nuclease superfamily 9 (31.2%) P-loop containing nucleoside triphosphate hydrolase (30%)" SLHNLESSYFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (20.1%) GO:0006189 (12.7%) GO:0006164 (7.3%)" "GO:0004044 (20.1%) GO:0046872 (19.5%) GO:0051536 (19.5%)" "purine nucleobase biosynthetic process (20.1%) 'de novo' IMP biosynthetic process (12.7%) purine nucleotide biosynthetic process (7.3%)" "amidophosphoribosyltransferase activity (20.1%) metal ion binding (19.5%) iron-sulfur cluster binding (19.5%)" "IPR017932 (20.4%) IPR029055 (20.4%) IPR000836 (20.2%)" "Glutamine amidotransferase type 2 domain (20.4%) Nucleophile aminohydrolases, N-terminal (20.4%) Phosphoribosyltransferase domain (20.2%)" LPVALFVVDVMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" YYLTASLR root "GO:0044718 (4.9%) GO:0006826 (4.2%)" "GO:0009279 (81.1%) GO:0016020 (2.1%)" "GO:0015344 (4.9%) GO:0016787 (1.4%) GO:0015179 (0.7%)" "siderophore transmembrane transport (4.9%) iron ion transport (4.2%)" "cell outer membrane (81.1%) membrane (2.1%)" "siderophore uptake transmembrane transporter activity (4.9%) hydrolase activity (1.4%) L-amino acid transmembrane transporter activity (0.7%)" "IPR023996 (13.6%) IPR039426 (13.6%) IPR012910 (13.5%)" "TonB-dependent outer membrane protein, SusC/RagA (13.6%) TonB-dependent receptor-like (13.6%) TonB-dependent receptor, plug domain (13.5%)" AATLADEVLAGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLLYHFMLFSDEK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.8%) GO:0005737 (16.4%)" "GO:0003677 (16.7%) GO:0003899 (16.7%) GO:0046983 (16.7%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.8%) cytoplasm (16.4%)" "DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%)" "IPR011263 (16.8%) IPR011260 (16.8%) IPR036603 (16.8%)" "DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.8%) RNA polymerase, alpha subunit, C-terminal (16.8%) RNA polymerase, RBP11-like subunit (16.8%)" TVGVCPVGCAVFAYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.7 (100%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) (100%) GO:0044281 (32.5%) "GO:0030976 (33.8%) GO:0016625 (32.5%) GO:0043807 (1.3%)" small molecule metabolic process (32.5%) "thiamine pyrophosphate binding (33.8%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor (32.5%) 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity (1.3%)" "IPR011766 (33.3%) IPR029061 (33.3%) IPR051457 (33.3%)" "Thiamine pyrophosphate enzyme, TPP-binding (33.3%) Thiamin diphosphate-binding fold (33.3%) 2-oxoacid:ferredoxin oxidoreductase (33.3%)" GSNYMDALAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.2.2.12 (100%) P-type Zn(2+) transporter (100%) GO:0005886 (16.7%) "GO:0005524 (16.7%) GO:0015086 (16.7%) GO:0016887 (16.7%)" plasma membrane (16.7%) "ATP binding (16.7%) cadmium ion transmembrane transporter activity (16.7%) ATP hydrolysis activity (16.7%)" "IPR001757 (10.3%) IPR018303 (10.3%) IPR027256 (10.3%)" "P-type ATPase (10.3%) P-type ATPase, phosphorylation site (10.3%) P-type ATPase, subfamily IB (10.3%)" KYEDALAQPGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR014941 (100%) Fimbrium subunit FimB/Mfa2/Mfa3 (100%) TWGLMGAYNLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" LDWNLNEFNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR039426 (17.3%) IPR057601 (17.3%) IPR008969 (16.7%)" "TonB-dependent receptor-like (17.3%) TonB-dependent transporter Oar-like, beta-barrel domain (17.3%) Carboxypeptidase-like, regulatory domain superfamily (16.7%)" LAFLGGPNHLDMVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000976 (50%) GO:0003700 (50%)" "transcription cis-regulatory region binding (50%) DNA-binding transcription factor activity (50%)" "IPR000843 (25.6%) IPR010982 (24.4%) IPR028082 (24.4%)" "LacI-type HTH domain (25.6%) Lambda repressor-like, DNA-binding domain superfamily (24.4%) Periplasmic binding protein-like I (24.4%)" GEYSYNSYMHGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (83.3%) IPR011250 (16.7%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (83.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16.7%)" LTSWLDLK root "2.1.1.220 (89.5%) 2.7.11.1 (5.3%) 2.7.13.3 (5.3%)" "tRNA (adenine(58)-N(1))-methyltransferase (89.5%) non-specific serine/threonine protein kinase (5.3%) histidine kinase (5.3%)" "GO:0030488 (12.7%) GO:0006405 (1.5%) GO:0006611 (1.5%)" "GO:0009279 (22.4%) GO:0005634 (14.2%) GO:0031515 (12.7%)" "GO:0160107 (12.7%) GO:0005524 (2.2%) GO:0003723 (1.5%)" "tRNA methylation (12.7%) RNA export from nucleus (1.5%) protein export from nucleus (1.5%)" "cell outer membrane (22.4%) nucleus (14.2%) tRNA (m1A) methyltransferase complex (12.7%)" "tRNA (adenine(58)-N1)-methyltransferase activity (12.7%) ATP binding (2.2%) RNA binding (1.5%)" "IPR036942 (23.3%) IPR014816 (13.2%) IPR029063 (13.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (23.3%) tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 (13.2%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (13.2%)" TYLWAASPLMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.1%) IPR012944 (33.8%) IPR011990 (31.1%)" "SusD-like, N-terminal (35.1%) RagB/SusD domain (33.8%) Tetratricopeptide-like helical domain superfamily (31.1%)" EEFASLLMK root GO:0034982 (5.9%) "GO:0009279 (64.7%) GO:0005745 (5.9%)" "GO:0004176 (5.9%) GO:0004222 (5.9%) GO:0005524 (5.9%)" mitochondrial protein processing (5.9%) "cell outer membrane (64.7%) m-AAA complex (5.9%)" "ATP-dependent peptidase activity (5.9%) metalloendopeptidase activity (5.9%) ATP binding (5.9%)" "IPR017689 (26.2%) IPR039565 (26.2%) IPR011990 (23.8%)" "Outer membrane protein assembly factor BamD (26.2%) Outer membrane lipoprotein BamD-like (26.2%) Tetratricopeptide-like helical domain superfamily (23.8%)" YSWKPEGGAPLLEDLPEEEMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" DLLMQSLVPANTGYSYQFQNFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (37.5%) GO:0009279 (62.5%) iron ion transport (37.5%) cell outer membrane (62.5%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VVVEVVNPLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (16.5%) "GO:0005737 (16.5%) GO:0005840 (16.5%) GO:1990904 (16.5%)" "GO:0003735 (16.5%) GO:0019843 (16.5%) GO:0016853 (0.9%)" translation (16.5%) "cytoplasm (16.5%) ribosome (16.5%) ribonucleoprotein complex (16.5%)" "structural constituent of ribosome (16.5%) rRNA binding (16.5%) isomerase activity (0.9%)" "IPR001787 (32.1%) IPR028909 (32.1%) IPR036164 (32.1%)" "Large ribosomal subunit protein bL21 (32.1%) Large ribosomal subunit protein bL21-like (32.1%) Large ribosomal subunit protein bL21-like superfamily (32.1%)" ETVSAYAAAK Bacteria Bacteria "1.1.1.69 (97.6%) 1.1.1.125 (1.8%) 1.1.1.127 (0.5%)" "gluconate 5-dehydrogenase (97.6%) 2-deoxy-D-gluconate 3-dehydrogenase (1.8%) 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (0.5%)" "GO:0008206 (38.3%) GO:0006633 (0.2%)" GO:0016020 (3.7%) "GO:0008874 (25.5%) GO:0016491 (16.6%) GO:0016616 (14.9%)" "bile acid metabolic process (38.3%) fatty acid biosynthetic process (0.2%)" membrane (3.7%) "gluconate 5-dehydrogenase activity (25.5%) oxidoreductase activity (16.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (14.9%)" "IPR002347 (32.7%) IPR036291 (32.7%) IPR020904 (32.7%)" "Short-chain dehydrogenase/reductase SDR (32.7%) NAD(P)-binding domain superfamily (32.7%) Short-chain dehydrogenase/reductase, conserved site (32.7%)" DNLEAFGGDPNR root 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0006581 (2.6%) GO:0017000 (2.6%) GO:0019695 (2.6%)" "GO:0005615 (2.6%) GO:0005886 (2.6%) GO:0016020 (2.6%)" "GO:0016787 (72.7%) GO:0052689 (5.2%) GO:0003990 (2.6%)" "acetylcholine catabolic process (2.6%) antibiotic biosynthetic process (2.6%) choline metabolic process (2.6%)" "extracellular space (2.6%) plasma membrane (2.6%) membrane (2.6%)" "hydrolase activity (72.7%) carboxylic ester hydrolase activity (5.2%) acetylcholinesterase activity (2.6%)" "IPR002018 (21.5%) IPR029058 (20.9%) IPR019826 (20.2%)" "Carboxylesterase, type B (21.5%) Alpha/Beta hydrolase fold (20.9%) Carboxylesterase type B, active site (20.2%)" EFFNTELPQVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.4.1.13 (100%) cysteine-S-conjugate beta-lyase (100%) "GO:0008483 (33.3%) GO:0016829 (33.3%) GO:0030170 (33.3%)" "transaminase activity (33.3%) lyase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR004839 (17.3%) IPR027619 (17.3%) IPR051798 (17.3%)" "Aminotransferase, class I/classII, large domain (17.3%) C-S lyase, PatB-like (17.3%) Class-II Pyridoxal-Phosphate-Dependent Aminotransferase (17.3%)" GSESVDLDHLSLFPEDNWNGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17.1%) IPR010720 (17.1%) IPR051563 (17.1%)" "Carbohydrate-binding, CenC-like (17.1%) Alpha-L-arabinofuranosidase, C-terminal (17.1%) Glycosyl Hydrolase Family 51 (17.1%)" LLVDTYGGK root 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%) GO:0006605 (0%)" "GO:0005737 (16.3%) GO:0005829 (0%) GO:0016020 (0%)" "GO:0004478 (16.7%) GO:0005524 (16.7%) GO:0000287 (16%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%) protein targeting (0%)" "cytoplasm (16.3%) cytosol (0%) membrane (0%)" "methionine adenosyltransferase activity (16.7%) ATP binding (16.7%) magnesium ion binding (16%)" "IPR002133 (16.7%) IPR022630 (16.7%) IPR022631 (16.7%)" "S-adenosylmethionine synthetase (16.7%) S-adenosylmethionine synthetase, C-terminal (16.7%) S-adenosylmethionine synthetase, conserved site (16.7%)" EMEDAVDDDMTFATVHVLGQAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0004601 (50%) GO:0005506 (50%)" "peroxidase activity (50%) iron ion binding (50%)" "IPR003251 (12.5%) IPR009040 (12.5%) IPR009078 (12.5%)" "Rubrerythrin, diiron-binding domain (12.5%) Ferritin-like diiron domain (12.5%) Ferritin-like superfamily (12.5%)" SYMPALNALQEMLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) "GO:0003824 (37.2%) GO:0016787 (12.8%)" carbohydrate metabolic process (50%) "catalytic activity (37.2%) hydrolase activity (12.8%)" "IPR004300 (33.9%) IPR052046 (33.9%) IPR011330 (32.2%)" "Glycoside hydrolase family 57, N-terminal domain (33.9%) Glycosyl hydrolase family 57 (33.9%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (32.2%)" NETLAVLGYGLQGPGQACNLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.86 (89.7%) 1.1.1.- (10.3%)" "ketol-acid reductoisomerase (NADP(+)) (89.7%) With NAD(+) or NADP(+) as acceptor (10.3%)" "GO:0009097 (21.3%) GO:0009099 (21.3%)" "GO:0004455 (21.3%) GO:0046872 (20.5%) GO:0016853 (15.6%)" "isoleucine biosynthetic process (21.3%) L-valine biosynthetic process (21.3%)" "ketol-acid reductoisomerase activity (21.3%) metal ion binding (20.5%) isomerase activity (15.6%)" "IPR000506 (17%) IPR013023 (17%) IPR013116 (17%)" "Ketol-acid reductoisomerase, C-terminal (17%) Ketol-acid reductoisomerase (17%) Ketol-acid reductoisomerase, N-terminal (17%)" KASVVGSLAQTTGEVLER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (9.1%) GO:0009279 (81.8%) GO:0015344 (9.1%) siderophore transmembrane transport (9.1%) cell outer membrane (81.8%) siderophore uptake transmembrane transporter activity (9.1%) "IPR012910 (15.8%) IPR023997 (15.8%) IPR039426 (15.8%)" "TonB-dependent receptor, plug domain (15.8%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.8%) TonB-dependent receptor-like (15.8%)" LDLTNLDALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.133 (100%) dTDP-4-dehydrorhamnose reductase (100%) GO:0019305 (33%) "GO:0005829 (33%) GO:0016020 (1.1%)" GO:0008831 (33%) dTDP-rhamnose biosynthetic process (33%) "cytosol (33%) membrane (1.1%)" dTDP-4-dehydrorhamnose reductase activity (33%) "IPR005913 (33.7%) IPR029903 (33.7%) IPR036291 (32.6%)" "dTDP-4-dehydrorhamnose reductase family (33.7%) RmlD-like substrate binding domain (33.7%) NAD(P)-binding domain superfamily (32.6%)" LNFFTNVSHELR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (18.8%) "GO:0000155 (21.6%) GO:0003700 (21.6%) GO:0043565 (21.6%)" membrane (18.8%) "phosphorelay sensor kinase activity (21.6%) DNA-binding transcription factor activity (21.6%) sequence-specific DNA binding (21.6%)" "IPR001789 (6.8%) IPR003594 (6.8%) IPR003661 (6.8%)" "Signal transduction response regulator, receiver domain (6.8%) Histidine kinase/HSP90-like ATPase domain (6.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (6.8%)" WKGENADLLTAMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.7%) GO:0009099 (16.7%)" GO:0005829 (16.7%) "GO:0000287 (16.7%) GO:0004160 (16.7%) GO:0051537 (16.7%)" "isoleucine biosynthetic process (16.7%) L-valine biosynthetic process (16.7%)" cytosol (16.7%) "magnesium ion binding (16.7%) dihydroxy-acid dehydratase activity (16.7%) 2 iron, 2 sulfur cluster binding (16.7%)" "IPR000581 (16.9%) IPR004404 (16.9%) IPR020558 (16.9%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (16.9%) Dihydroxy-acid dehydratase (16.9%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.9%)" LLLPVQMEALSVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (35%) IPR050678 (35%) IPR027417 (30%)" "AAA domain (35%) DNA Partitioning ATPase (35%) P-loop containing nucleoside triphosphate hydrolase (30%)" LLTGTPFQEGETPALTNSDAWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" QDGPTAQGHFDTHEMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009060 (22.7%) GO:0022904 (22.7%)" "GO:0009055 (27.3%) GO:0051537 (27.3%)" "aerobic respiration (22.7%) respiratory electron transport chain (22.7%)" "electron transfer activity (27.3%) 2 iron, 2 sulfur cluster binding (27.3%)" "IPR006058 (15.4%) IPR012675 (15.4%) IPR025192 (15.4%)" "2Fe-2S ferredoxin, iron-sulphur binding site (15.4%) Beta-grasp domain superfamily (15.4%) Succinate dehydogenase/fumarate reductase N-terminal (15.4%)" NPAALAPTNLQLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0071470 (33.3%) GO:0005886 (33.3%) GO:0008381 (33.3%) cellular response to osmotic stress (33.3%) plasma membrane (33.3%) mechanosensitive monoatomic ion channel activity (33.3%) "IPR006685 (25.8%) IPR030192 (25.8%) IPR010920 (24.2%)" "Mechanosensitive ion channel MscS (25.8%) Miniconductance mechanosensitive channel YbdG (25.8%) LSM domain superfamily (24.2%)" SEHGFDTNLGDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005886 (23.7%) GO:0016020 (0.8%)" "GO:0005524 (24.6%) GO:0016887 (24.6%) GO:0015421 (22.9%)" "plasma membrane (23.7%) membrane (0.8%)" "ATP binding (24.6%) ATP hydrolysis activity (24.6%) ABC-type oligopeptide transporter activity (22.9%)" "IPR003439 (14.4%) IPR003593 (14.4%) IPR011527 (14.4%)" "ABC transporter-like, ATP-binding domain (14.4%) AAA+ ATPase domain (14.4%) ABC transporter type 1, transmembrane domain (14.4%)" VADAFFGEDVDAESLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.3.1 (100%) threonine synthase (100%) GO:0009088 (33.3%) "GO:0004795 (33.3%) GO:0030170 (33.3%)" threonine biosynthetic process (33.3%) "threonine synthase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000634 (14.5%) IPR001926 (14.5%) IPR004450 (14.5%)" "Serine/threonine dehydratase, pyridoxal-phosphate-binding site (14.5%) Tryptophan synthase beta chain-like, PALP domain (14.5%) Threonine synthase-like (14.5%)" NKQEAPAYDFSNLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.9%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.9%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.7%) IPR003593 (10.7%) IPR004665 (10.7%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.7%) AAA+ ATPase domain (10.7%) Transcription termination factor Rho (10.7%)" AFAGNEAWVLSYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.5%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.5%)" "IPR000241 (17%) IPR002052 (17%) IPR004114 (16.6%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17%) DNA methylase, N-6 adenine-specific, conserved site (17%) THUMP domain (16.6%)" ALLYMGVGGCETGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" VGELLAEK root "2.7.1.71 (25%) 1.1.1.22 (8.3%) 1.3.1.48 (8.3%)" "shikimate kinase (25%) UDP-glucose 6-dehydrogenase (8.3%) 15-oxoprostaglandin 13-reductase (8.3%)" "GO:0006412 (13.5%) GO:0055085 (2.3%) GO:0000045 (1.8%)" "GO:0022625 (11.5%) GO:0005737 (4.8%) GO:0005886 (2.8%)" "GO:0003735 (13.5%) GO:0008097 (11.7%) GO:0003746 (3.8%)" "translation (13.5%) transmembrane transport (2.3%) autophagosome assembly (1.8%)" "cytosolic large ribosomal subunit (11.5%) cytoplasm (4.8%) plasma membrane (2.8%)" "structural constituent of ribosome (13.5%) 5S rRNA binding (11.7%) translation elongation factor activity (3.8%)" "IPR005484 (10.1%) IPR004389 (9.8%) IPR057268 (9.4%)" "Large ribosomal subunit protein uL18, bacterial/plantae/animalia (10.1%) Large ribosomal subunit protein uL18, bacteria (9.8%) Large ribosomal subunit protein uL18 (9.4%)" LFYDKNQDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005615 (62.5%) GO:0005737 (12.5%) GO:0005886 (12.5%)" "extracellular space (62.5%) cytoplasm (12.5%) plasma membrane (12.5%)" "IPR001611 (16.4%) IPR027899 (15.7%) IPR041403 (15.7%)" "Leucine-rich repeat (16.4%) Domain of unknown function DUF4458 (15.7%) DUF4458 domain-containing protein, leucine-rich repeat (15.7%)" NLMNYQEQNTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (8.8%) GO:0009279 (91.2%) iron ion transport (8.8%) cell outer membrane (91.2%) "IPR012910 (14.2%) IPR023996 (14.2%) IPR023997 (14.2%)" "TonB-dependent receptor, plug domain (14.2%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.2%)" VTGAHTYGGHGEQMAVFASQVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.37 (60%) 1.1.1.40 (40%)" "malate dehydrogenase (60%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (40%)" "GO:0006108 (34.3%) GO:0006089 (1.5%)" GO:0016020 (0.7%) "GO:0016615 (27.6%) GO:0016616 (27.6%) GO:0030060 (3.7%)" "malate metabolic process (34.3%) lactate metabolic process (1.5%)" membrane (0.7%) "malate dehydrogenase activity (27.6%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (27.6%) L-malate dehydrogenase (NAD+) activity (3.7%)" "IPR001236 (16.8%) IPR001557 (16.8%) IPR015955 (16.8%)" "Lactate/malate dehydrogenase, N-terminal (16.8%) L-lactate/malate dehydrogenase (16.8%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.8%)" GVDLFSFDHLDESDPEVFGATNPLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" TFGLWAK root "3.1.1.- (83.3%) 3.1.6.1 (8.3%) 4.2.2.- (8.3%)" "Carboxylic ester hydrolases (83.3%) arylsulfatase (type I) (8.3%) Acting on polysaccharides (8.3%)" "GO:0016020 (3.7%) GO:0005737 (0.6%)" "GO:0016788 (88.3%) GO:0022857 (2.5%) GO:0004065 (0.6%)" "membrane (3.7%) cytoplasm (0.6%)" "hydrolase activity, acting on ester bonds (88.3%) transmembrane transporter activity (2.5%) arylsulfatase activity (0.6%)" "IPR036514 (24.5%) IPR037459 (24.5%) IPR013830 (24%)" "SGNH hydrolase superfamily (24.5%) Rhamnogalacturonan acetylesterase RhgT-like (24.5%) SGNH hydrolase-type esterase domain (24%)" MVMAGFGPVGTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (43.6%) "GO:0052689 (43.6%) GO:0004557 (12.8%)" cell outer membrane (43.6%) "carboxylic ester hydrolase activity (43.6%) alpha-galactosidase activity (12.8%)" "IPR032812 (25.8%) IPR044060 (25.8%) IPR011050 (24.2%)" "SbsA, Ig-like domain (25.8%) Bacterial repeat domain (25.8%) Pectin lyase fold/virulence factor (24.2%)" TEFELLR root "2.7.7.7 (32.7%) 2.7.4.16 (10.6%) 5.3.1.28 (6.7%)" "DNA-directed DNA polymerase (32.7%) thiamine-phosphate kinase (10.6%) D-sedoheptulose-7-phosphate isomerase (6.7%)" "GO:0006355 (17.1%) GO:0045893 (0.6%) GO:0015031 (0.4%)" "GO:0005829 (18%) GO:0032993 (17.7%) GO:0005886 (0.7%)" "GO:0000156 (17.7%) GO:0000976 (17.1%) GO:0042802 (0.6%)" "regulation of DNA-templated transcription (17.1%) positive regulation of DNA-templated transcription (0.6%) protein transport (0.4%)" "cytosol (18%) protein-DNA complex (17.7%) plasma membrane (0.7%)" "phosphorelay response regulator activity (17.7%) transcription cis-regulatory region binding (17.1%) identical protein binding (0.6%)" "IPR036388 (16.3%) IPR001867 (16.3%) IPR039420 (16.3%)" "Winged helix-like DNA-binding domain superfamily (16.3%) OmpR/PhoB-type DNA-binding domain (16.3%) Transcriptional regulatory protein WalR-like (16.3%)" AMVYFDLVR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34%) IPR033985 (34%) IPR012944 (32.1%)" "Tetratricopeptide-like helical domain superfamily (34%) SusD-like, N-terminal (34%) RagB/SusD domain (32.1%)" NVLQASTATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.5%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.5%)" VNRVELQDLTPPESVLQAMEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006508 (4%) "GO:0005886 (46%) GO:0098552 (46%)" GO:0008233 (4%) proteolysis (4%) "plasma membrane (46%) side of membrane (46%)" peptidase activity (4%) "IPR001107 (20.3%) IPR018080 (20.3%) IPR036013 (20.3%)" "Band 7 domain (20.3%) Band 7/stomatin-like, conserved site (20.3%) Band 7/SPFH domain superfamily (20.3%)" YTLVDGHSATTLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.4%) IPR024742 (20.4%) IPR032790 (20.4%)" "Glycogen debranching enzyme (20.4%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.4%) Glycogen debranching enzyme, C-terminal (20.4%)" WLTTFGK root "2.3.3.21 (33.3%) 2.3.1.182 (16.7%) 2.4.1.- (16.7%)" "(R)-citramalate synthase (33.3%) Transferred entry: 2.3.3.21 (16.7%) Hexosyltransferases (16.7%)" "GO:0051607 (3.6%) GO:0009097 (2.4%) GO:0009098 (2.4%)" "GO:0043190 (21.7%) GO:0005789 (1.2%) GO:0005829 (1.2%)" "GO:0005548 (21.7%) GO:0005524 (4.8%) GO:0016787 (4.8%)" "defense response to virus (3.6%) isoleucine biosynthetic process (2.4%) L-leucine biosynthetic process (2.4%)" "ATP-binding cassette (ABC) transporter complex (21.7%) endoplasmic reticulum membrane (1.2%) cytosol (1.2%)" "phospholipid transporter activity (21.7%) ATP binding (4.8%) hydrolase activity (4.8%)" "IPR030802 (21.7%) IPR001650 (3.6%) IPR006474 (3.6%)" "ABC transporter permease MalE (21.7%) Helicase, C-terminal domain-like (3.6%) Helicase Cas3, CRISPR-associated, core (3.6%)" GLNDLNNTAQTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.5%) IPR023997 (15.5%) IPR039426 (15.5%)" "TonB-dependent receptor, plug domain (15.5%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.5%) TonB-dependent receptor-like (15.5%)" GYSSNSGNLGPLLLVDGLK Pseudomonadati Bacteria Pseudomonadati GO:0044718 (5%) GO:0009279 (90%) GO:0015344 (5%) siderophore transmembrane transport (5%) cell outer membrane (90%) siderophore uptake transmembrane transporter activity (5%) "IPR012910 (13.9%) IPR037066 (13.9%) IPR039426 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent receptor, plug domain superfamily (13.9%) TonB-dependent receptor-like (13.9%)" ENWSLHGCPLNVFLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (30.4%) "GO:0005525 (30.4%) GO:0043022 (30.4%) GO:0016787 (8.9%)" ribosome biogenesis (30.4%) "GTP binding (30.4%) ribosome binding (30.4%) hydrolase activity (8.9%)" "IPR005225 (14.3%) IPR006073 (14.3%) IPR015946 (14.3%)" "Small GTP-binding domain (14.3%) GTP binding domain (14.3%) K homology domain-like, alpha/beta (14.3%)" LPGVYSPLPMGAFYTVAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.6.1.1 (67.8%) 2.6.1.- (32.2%)" "aspartate transaminase (67.8%) Transaminases (32.2%)" GO:0006520 (33.2%) "GO:0030170 (33.2%) GO:0008483 (28.1%) GO:0004069 (5.5%)" amino acid metabolic process (33.2%) "pyridoxal phosphate binding (33.2%) transaminase activity (28.1%) L-aspartate:2-oxoglutarate aminotransferase activity (5.5%)" "IPR004839 (20.1%) IPR050596 (20.1%) IPR015421 (19.9%)" "Aminotransferase, class I/classII, large domain (20.1%) Aspartate/prephenate aminotransferase-like (20.1%) Pyridoxal phosphate-dependent transferase, major domain (19.9%)" LLAASMVEK root "2.2.1.1 (97.3%) 2.2.1.- (2.7%)" "transketolase (97.3%) Transketolases and transaldolases (2.7%)" GO:0006098 (24.8%) "GO:0005829 (24.8%) GO:0016020 (0.3%)" "GO:0046872 (24.9%) GO:0004802 (24.8%) GO:0047896 (0.2%)" pentose-phosphate shunt (24.8%) "cytosol (24.8%) membrane (0.3%)" "metal ion binding (24.9%) transketolase activity (24.8%) formaldehyde transketolase activity (0.2%)" "IPR005474 (12.9%) IPR029061 (12.8%) IPR049557 (12.8%)" "Transketolase, N-terminal (12.9%) Thiamin diphosphate-binding fold (12.8%) Transketolase conserved site (12.8%)" QGLLLVDTKYEFGK root 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) GO:0006189 (25%) "GO:0005737 (24.7%) GO:0009570 (0.3%)" "GO:0004639 (25%) GO:0005524 (25%)" 'de novo' IMP biosynthetic process (25%) "cytoplasm (24.7%) chloroplast stroma (0.3%)" "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (25%) ATP binding (25%)" "IPR018236 (50%) IPR028923 (50%)" "SAICAR synthetase, conserved site (50%) SAICAR synthetase/ADE2, N-terminal (50%)" LAATTPTLDGLLQGTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (4.5%) GO:0009279 (90.9%) GO:0015344 (4.5%) siderophore transmembrane transport (4.5%) cell outer membrane (90.9%) siderophore uptake transmembrane transporter activity (4.5%) "IPR012910 (15.4%) IPR023997 (15.4%) IPR039426 (15.4%)" "TonB-dependent receptor, plug domain (15.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.4%) TonB-dependent receptor-like (15.4%)" DHAGVLFDGFPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.4.3 (90.9%) 2.7.4.- (9.1%)" "adenylate kinase (90.9%) Phosphotransferases with a phosphate group as acceptor (9.1%)" "GO:0044209 (22.9%) GO:0006139 (2.9%)" GO:0005737 (22.9%) "GO:0005524 (25.7%) GO:0004017 (22.9%) GO:0019205 (2.9%)" "AMP salvage (22.9%) nucleobase-containing compound metabolic process (2.9%)" cytoplasm (22.9%) "ATP binding (25.7%) AMP kinase activity (22.9%) nucleobase-containing compound kinase activity (2.9%)" "IPR000850 (33.3%) IPR027417 (33.3%) IPR033690 (33.3%)" "Adenylate kinase/UMP-CMP kinase (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) Adenylate kinase, conserved site (33.3%)" TCDTFEEGLDQAVDSMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR003489 (50%) IPR036567 (50%)" "Ribosome hibernation promoting factor/RaiA (50%) Ribosome hibernation promotion factor-like (50%)" EGYDLVSGYK Pseudomonadati Bacteria Pseudomonadati 2.4.-.- (100%) Glycosyltransferases (100%) GO:0009103 (33.3%) GO:0005886 (33.3%) GO:0099621 (33.3%) lipopolysaccharide biosynthetic process (33.3%) plasma membrane (33.3%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (33.3%) "IPR001173 (33.5%) IPR050256 (33.5%) IPR029044 (33%)" "Glycosyltransferase 2-like (33.5%) Glycosyltransferase 2 (33.5%) Nucleotide-diphospho-sugar transferases (33%)" SRLEFDELSTVPFVEEDEEGNDLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.3%) IPR006592 (9.3%) IPR007066 (9.3%)" "RNA polymerase, alpha subunit (9.3%) RNA polymerase, N-terminal (9.3%) RNA polymerase Rpb1, domain 3 (9.3%)" GYAHALLAQLAMTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NEVSVKPQLSGLLTELCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" VLPALNPYASNYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" TVTWSATNTDNETK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (58.3%) "GO:0016787 (33.3%) GO:0016829 (8.3%)" carbohydrate metabolic process (58.3%) "hydrolase activity (33.3%) lyase activity (8.3%)" "IPR013783 (26.7%) IPR031965 (26.7%) IPR006047 (23.3%)" "Immunoglobulin-like fold (26.7%) Starch-binding module 26 (26.7%) Glycosyl hydrolase family 13, catalytic domain (23.3%)" LAGDFYWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR010870 (51.7%) IPR023614 (48.3%)" "Phosphate-selective porin O/P (51.7%) Porin domain superfamily (48.3%)" LFSLLANVADVK root "2.5.1.49 (56.9%) 4.4.1.11 (36.7%) 2.5.1.47 (3%)" "O-acetylhomoserine aminocarboxypropyltransferase (56.9%) methionine gamma-lyase (36.7%) cysteine synthase (3%)" "GO:0019346 (13.7%) GO:0071269 (13.7%) GO:0006535 (13.7%)" "GO:0005737 (13.7%) GO:0016020 (0%) GO:0005829 (0%)" "GO:0030170 (13.7%) GO:0004124 (13.7%) GO:0003961 (13.7%)" "transsulfuration (13.7%) L-homocysteine biosynthetic process (13.7%) cysteine biosynthetic process from serine (13.7%)" "cytoplasm (13.7%) membrane (0%) cytosol (0%)" "pyridoxal phosphate binding (13.7%) cysteine synthase activity (13.7%) O-acetylhomoserine aminocarboxypropyltransferase activity (13.7%)" "IPR000277 (16.7%) IPR006235 (16.7%) IPR015424 (16.7%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (16.7%) O-acetylhomoserine/O-acetylserine sulfhydrylase (16.7%) Pyridoxal phosphate-dependent transferase (16.7%)" SSTPTADQMSELLANTTQTEVEVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YYSMQVNSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YRLPTEAEWEYAAR root "2.7.11.1 (78.6%) 1.14.99.50 (11.9%) 1.8.3.7 (8.3%)" "non-specific serine/threonine protein kinase (78.6%) gamma-glutamyl hercynylcysteine S-oxide synthase (11.9%) formylglycine-generating enzyme (8.3%)" "GO:0006508 (5.3%) GO:0007165 (0.8%) GO:0005975 (0.2%)" "GO:0016020 (9.2%) GO:0030313 (4.4%) GO:0005576 (0.2%)" "GO:0120147 (61.4%) GO:0004197 (5.3%) GO:0004674 (4.7%)" "proteolysis (5.3%) signal transduction (0.8%) carbohydrate metabolic process (0.2%)" "membrane (9.2%) cell envelope (4.4%) extracellular region (0.2%)" "formylglycine-generating oxidase activity (61.4%) cysteine-type endopeptidase activity (5.3%) protein serine/threonine kinase activity (4.7%)" "IPR005532 (20.7%) IPR016187 (20.6%) IPR042095 (20.6%)" "Sulfatase-modifying factor enzyme-like domain (20.7%) C-type lectin fold (20.6%) Sulfatase-modifying factor enzyme superfamily (20.6%)" EADKVEFLSGVFEGK Pseudomonadati Bacteria Pseudomonadati 4.2.3.5 (100%) chorismate synthase (100%) "GO:0008652 (16.7%) GO:0009073 (16.7%) GO:0009423 (16.7%)" GO:0005829 (16.7%) "GO:0004107 (16.7%) GO:0010181 (16.7%)" "amino acid biosynthetic process (16.7%) aromatic amino acid family biosynthetic process (16.7%) chorismate biosynthetic process (16.7%)" cytosol (16.7%) "chorismate synthase activity (16.7%) FMN binding (16.7%)" "IPR000453 (34%) IPR020541 (34%) IPR035904 (32%)" "Chorismate synthase (34%) Chorismate synthase, conserved site (34%) Chorismate synthase AroC superfamily (32%)" NHWFANSYWSNDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (34.8%) IPR011990 (30.4%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (30.4%)" AMSSFLNELNMEGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (53.1%) IPR032466 (46.9%)" "Uronate isomerase (53.1%) Metal-dependent hydrolase (46.9%)" DWTDATLKPGEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.3.3 (100%) aldose 1-epimerase (100%) "GO:0006006 (20.3%) GO:0033499 (20.3%)" GO:0005737 (20.3%) "GO:0004034 (20.3%) GO:0030246 (18.8%)" "glucose metabolic process (20.3%) galactose catabolic process via UDP-galactose, Leloir pathway (20.3%)" cytoplasm (20.3%) "aldose 1-epimerase activity (20.3%) carbohydrate binding (18.8%)" "IPR008183 (17.3%) IPR018052 (17.3%) IPR047215 (17.3%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.3%) Aldose 1-epimerase, conserved site (17.3%) Galactose mutarotase-like (17.3%)" MPLTLADADLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0016491 (50%) GO:0051536 (48.6%) GO:0004355 (1.4%)" "oxidoreductase activity (50%) iron-sulfur cluster binding (48.6%) glutamate synthase (NADPH) activity (1.4%)" "IPR017927 (11.4%) IPR017938 (11.1%) IPR019480 (11.1%)" "FAD-binding domain, ferredoxin reductase-type (11.4%) Riboflavin synthase-like beta-barrel (11.1%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.1%)" LASGASDYDYNWTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (30.7%) IPR017853 (29.6%) IPR013780 (29.3%)" "Alpha-L-arabinofuranosidase, C-terminal (30.7%) Glycoside hydrolase superfamily (29.6%) Glycosyl hydrolase, all-beta (29.3%)" ETYMATATLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (31.6%) GO:0009279 (36.8%) GO:0015344 (31.6%) siderophore transmembrane transport (31.6%) cell outer membrane (36.8%) siderophore uptake transmembrane transporter activity (31.6%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" RQYYGETAELLK Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.7%) GO:0006096 (12.7%) GO:0019563 (12.7%)" "GO:0005829 (12.7%) GO:0016020 (12%)" GO:0004807 (12.7%) "gluconeogenesis (12.7%) glycolytic process (12.7%) glycerol catabolic process (12.7%)" "cytosol (12.7%) membrane (12%)" triose-phosphate isomerase activity (12.7%) "IPR000652 (17.1%) IPR020861 (17.1%) IPR022896 (16.9%)" "Triosephosphate isomerase (17.1%) Triosephosphate isomerase, active site (17.1%) Triosephosphate isomerase, bacterial/eukaryotic (16.9%)" LSLLTEYALLNDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR010870 (51.9%) IPR023614 (48.1%)" "Phosphate-selective porin O/P (51.9%) Porin domain superfamily (48.1%)" SNVLPSVFPLGYDGLAFLVNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" HVSVCFESQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.1.3.3 (94%) 5.1.3.- (6%)" "aldose 1-epimerase (94%) Acting on carbohydrates and derivatives (6%)" "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19%)" "IPR008183 (17.2%) IPR018052 (17.2%) IPR047215 (17.2%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.2%) Aldose 1-epimerase, conserved site (17.2%) Galactose mutarotase-like (17.2%)" LFGPTKDYECACGK Bacteria Bacteria 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (17%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.1%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (17%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.1%)" "IPR007080 (9.2%) IPR045867 (9.2%) IPR044893 (9.1%)" "RNA polymerase Rpb1, domain 1 (9.2%) DNA-directed RNA polymerase, subunit beta-prime (9.2%) RNA polymerase Rpb1, clamp domain superfamily (9.1%)" DADQAVYHAVVAEQVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.3.4 (100%) L-ribulose-5-phosphate 4-epimerase (100%) GO:0019323 (20%) GO:0005829 (20%) "GO:0008742 (20%) GO:0016832 (20%) GO:0046872 (20%)" pentose catabolic process (20%) cytosol (20%) "L-ribulose-phosphate 4-epimerase activity (20%) aldehyde-lyase activity (20%) metal ion binding (20%)" "IPR001303 (33.3%) IPR036409 (33.3%) IPR050197 (33.3%)" "Class II aldolase/adducin N-terminal (33.3%) Class II aldolase/adducin N-terminal domain superfamily (33.3%) Aldolase class II family, sugar metabolism enzymes (33.3%)" NYLPFLGK root "2.7.10.2 (40%) 2.7.10.1 (20%) 2.7.11.22 (20%)" "non-specific protein-tyrosine kinase (40%) receptor protein-tyrosine kinase (20%) cyclin-dependent kinase (20%)" "GO:0015969 (25.5%) GO:0006412 (3.9%)" "GO:0005886 (26.5%) GO:0016020 (5.9%) GO:0005762 (3.9%)" "GO:0016787 (7.8%) GO:0003735 (3.9%) GO:0019843 (3.9%)" "guanosine tetraphosphate metabolic process (25.5%) translation (3.9%)" "plasma membrane (26.5%) membrane (5.9%) mitochondrial large ribosomal subunit (3.9%)" "hydrolase activity (7.8%) structural constituent of ribosome (3.9%) rRNA binding (3.9%)" "IPR002912 (7.9%) IPR003607 (7.9%) IPR004095 (7.9%)" "ACT domain (7.9%) HD/PDEase domain (7.9%) TGS (7.9%)" YVLDPHGACGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.3.1 (100%) threonine synthase (100%) GO:0009088 (33.3%) "GO:0004795 (33.3%) GO:0030170 (33.3%)" threonine biosynthetic process (33.3%) "threonine synthase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000634 (14.5%) IPR001926 (14.5%) IPR004450 (14.5%)" "Serine/threonine dehydratase, pyridoxal-phosphate-binding site (14.5%) Tryptophan synthase beta chain-like, PALP domain (14.5%) Threonine synthase-like (14.5%)" TFLLGVR root "4.2.1.3 (56.5%) 6.5.1.1 (11.8%) 6.1.1.9 (9.4%)" "aconitate hydratase (56.5%) DNA ligase (ATP) (11.8%) valine--tRNA ligase (9.4%)" "GO:0032784 (10.8%) GO:0006099 (3.6%) GO:0006354 (1.2%)" "GO:0009279 (5%) GO:0016020 (3.6%) GO:0005886 (1.8%)" "GO:0003677 (11.7%) GO:0003746 (10.4%) GO:0070063 (6.1%)" "regulation of DNA-templated transcription elongation (10.8%) tricarboxylic acid cycle (3.6%) DNA-templated transcription elongation (1.2%)" "cell outer membrane (5%) membrane (3.6%) plasma membrane (1.8%)" "DNA binding (11.7%) translation elongation factor activity (10.4%) RNA polymerase binding (6.1%)" "IPR001437 (7.3%) IPR036953 (7.3%) IPR023459 (4.2%)" "Transcription elongation factor, GreA/GreB, C-terminal (7.3%) Transcription elongation factor GreA/GreB, C-terminal domain superfamily (7.3%) Transcription elongation factor GreA/GreB family (4.2%)" WNLLVEK root "2.7.1.107 (96.1%) 6.1.1.10 (1.2%) 1.14.18.1 (0.4%)" "diacylglycerol kinase (ATP) (96.1%) methionine--tRNA ligase (1.2%) tyrosinase (0.4%)" "GO:0007200 (9.8%) GO:0046486 (8.1%) GO:0006629 (1.7%)" "GO:0005886 (10%) GO:0098978 (9.9%) GO:0005634 (9.1%)" "GO:0005524 (10.3%) GO:0004143 (9.9%) GO:0003779 (0.6%)" "phospholipase C-activating G protein-coupled receptor signaling pathway (9.8%) glycerolipid metabolic process (8.1%) lipid metabolic process (1.7%)" "plasma membrane (10%) glutamatergic synapse (9.9%) nucleus (9.1%)" "ATP binding (10.3%) ATP-dependent diacylglycerol kinase activity (9.9%) actin binding (0.6%)" "IPR001206 (8.1%) IPR016064 (8.1%) IPR017438 (8.1%)" "Diacylglycerol kinase, catalytic domain (8.1%) NAD kinase/diacylglycerol kinase-like domain superfamily (8.1%) Inorganic polyphosphate/ATP-NAD kinase, N-terminal (8.1%)" APFEQLEGYVLSPDGKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25%) IPR002469 (25%) IPR029058 (25%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25%) Dipeptidylpeptidase IV, N-terminal domain (25%) Alpha/Beta hydrolase fold (25%)" YASVGDVLVVAVK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000218 (25%) IPR005745 (25%) IPR019972 (25%)" "Large ribosomal subunit protein uL14 (25%) Large ribosomal subunit protein uL14, bacteria (25%) Large ribosomal subunit protein uL14, conserved site (25%)" KSHPTFDQVGLVWSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) FGLFTGSK root "GO:0009279 (90%) GO:0016020 (10%)" "cell outer membrane (90%) membrane (10%)" "IPR012944 (47.4%) IPR011990 (44.7%) IPR049214 (2.6%)" "RagB/SusD domain (47.4%) Tetratricopeptide-like helical domain superfamily (44.7%) Domain of unknown function DUF6808 (2.6%)" LTLCNLSLEMGAR Pseudomonadati Bacteria Pseudomonadati "4.2.1.33 (99.7%) 4.2.1.35 (0.3%)" "3-isopropylmalate dehydratase (99.7%) (R)-2-methylmalate dehydratase (0.3%)" GO:0009098 (24.8%) "GO:0046872 (24.8%) GO:0051539 (24.8%) GO:0003861 (24.5%)" L-leucine biosynthetic process (24.8%) "metal ion binding (24.8%) 4 iron, 4 sulfur cluster binding (24.8%) 3-isopropylmalate dehydratase activity (24.5%)" "IPR001030 (14.5%) IPR050067 (14.5%) IPR015931 (14.4%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.5%) Isopropylmalate dehydratase and related enzymes (14.5%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (14.4%)" QSFYANFFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (55.6%) IPR009057 (44.4%)" "AraC-like, DNA binding HTH domain (55.6%) Homedomain-like superfamily (44.4%)" SYLYTAPDGSQVSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VLWPSEEAEGGAPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.6%) GO:0006526 (13.5%) GO:0006221 (12.9%)" GO:0005737 (14.6%) "GO:0004088 (14.6%) GO:0005524 (14.6%) GO:0046872 (13.5%)" "glutamine metabolic process (14.6%) L-arginine biosynthetic process (13.5%) pyrimidine nucleotide biosynthetic process (12.9%)" cytoplasm (14.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.6%) ATP binding (14.6%) metal ion binding (13.5%)" "IPR011607 (11%) IPR036914 (11%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (11%) Methylglyoxal synthase-like domain superfamily (11%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" AVLNEATGQLTFYDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR000322 (11.1%) IPR011013 (11.1%) IPR013780 (11.1%)" "Glycoside hydrolase family 31, TIM barrel domain (11.1%) Galactose mutarotase-like domain superfamily (11.1%) Glycosyl hydrolase, all-beta (11.1%)" AALEEGLVAGGGTTYLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.1%) GO:0005737 (16.2%) "GO:0005524 (17.1%) GO:0140662 (17.1%) GO:0016853 (16.2%)" protein refolding (17.1%) cytoplasm (16.2%) "ATP binding (17.1%) ATP-dependent protein folding chaperone (17.1%) isomerase activity (16.2%)" "IPR001844 (17.5%) IPR002423 (17.5%) IPR018370 (17.5%)" "Chaperonin Cpn60/GroEL (17.5%) Chaperonin Cpn60/GroEL/TCP-1 family (17.5%) Chaperonin Cpn60, conserved site (17.5%)" TAPADDPLLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044874 (50%) GO:0098797 (50%) lipoprotein localization to outer membrane (50%) plasma membrane protein complex (50%) "IPR003838 (33.3%) IPR025857 (33.3%) IPR051447 (33.3%)" "ABC3 transporter permease, C-terminal (33.3%) MacB-like periplasmic core domain (33.3%) Lipoprotein-releasing system transmembrane protein (33.3%)" DAVGGVSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032167 (73.7%) IPR013783 (26.3%)" "Protein of unknown function DUF5003 (73.7%) Immunoglobulin-like fold (26.3%)" LMEAEAALKDAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0055085 (50%) GO:0016020 (50%) transmembrane transport (50%) membrane (50%) "IPR043602 (36.8%) IPR050739 (36.8%) IPR032317 (26.3%)" "Unknown (36.8%) Membrane Fusion Protein (36.8%) Unknown (26.3%)" LLNKVGLDAALNQAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001383 (25%) IPR026569 (25%) IPR034704 (25%)" "Large ribosomal subunit protein bL28, bacteria (25%) Large ribosomal subunit protein bL28 (25%) Large ribosomal subunit protein bL28/bL31-like superfamily (25%)" VLPDMGQLSSAQAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:1990281 (50%) GO:0015562 (50%) efflux pump complex (50%) efflux transmembrane transporter activity (50%) "IPR006143 (50%) IPR032317 (50%)" "RND efflux pump, membrane fusion protein (50%) Unknown (50%)" FQQNYNVGLNWKPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (29%) GO:0009279 (71%) iron ion transport (29%) cell outer membrane (71%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" TGLNMDAVR root GO:0016829 (100%) lyase activity (100%) IPR007841 (100%) Uncharacterised protein family UPF0210 (100%) GVMTDKEASDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (17%) "GO:0005737 (17%) GO:0005840 (17%) GO:1990904 (17%)" "GO:0003735 (17%) GO:0019843 (15.1%)" translation (17%) "cytoplasm (17%) ribosome (17%) ribonucleoprotein complex (17%)" "structural constituent of ribosome (17%) rRNA binding (15.1%)" "IPR000630 (50%) IPR035987 (50%)" "Small ribosomal subunit protein uS8 (50%) Small ribosomal subunit protein uS8 superfamily (50%)" SGLQGLLDSYLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006508 (21.7%) GO:0009636 (18.8%) GO:0043418 (18.8%)" GO:0005737 (18.8%) GO:0070005 (21.7%) "proteolysis (21.7%) response to toxic substance (18.8%) homocysteine catabolic process (18.8%)" cytoplasm (18.8%) cysteine-type aminopeptidase activity (21.7%) "IPR004134 (32.6%) IPR000169 (30.4%) IPR038765 (30.4%)" "Peptidase C1B, bleomycin hydrolase (32.6%) Cysteine peptidase, cysteine active site (30.4%) Papain-like cysteine peptidase superfamily (30.4%)" EKLDYLMELK Bacteroidota Bacteria Pseudomonadati Bacteroidota "1.4.1.3 (50%) 1.4.1.4 (50%)" "glutamate dehydrogenase [NAD(P)(+)] (50%) glutamate dehydrogenase (NADP(+)) (50%)" GO:0006537 (25.5%) GO:0005829 (25.3%) "GO:0004354 (25.5%) GO:0000166 (23.5%) GO:0004352 (0.2%)" glutamate biosynthetic process (25.5%) cytosol (25.3%) "glutamate dehydrogenase (NADP+) activity (25.5%) nucleotide binding (23.5%) glutamate dehydrogenase (NAD+) activity (0.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR033922 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) NAD(P) binding domain of glutamate dehydrogenase (11.1%)" LLELLYTHLSMLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045892 (4.5%) "GO:0003677 (90.9%) GO:0003700 (4.5%)" negative regulation of DNA-templated transcription (4.5%) "DNA binding (90.9%) DNA-binding transcription factor activity (4.5%)" "IPR001647 (32.8%) IPR009057 (32.8%) IPR050624 (32.8%)" "DNA-binding HTH domain, TetR-type (32.8%) Homedomain-like superfamily (32.8%) HTH-type Transcriptional Regulator (32.8%)" FENPFVDHQVTSLMLNSFPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (31.3%) GO:0005829 (31.3%) "GO:0008926 (31.3%) GO:0009026 (6.1%)" mannitol catabolic process (31.3%) cytosol (31.3%) "mannitol-1-phosphate 5-dehydrogenase activity (31.3%) tagaturonate reductase activity (6.1%)" "IPR013118 (21.2%) IPR013131 (21.2%) IPR008927 (19.2%)" "Mannitol dehydrogenase, C-terminal (21.2%) Mannitol dehydrogenase, N-terminal (21.2%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (19.2%)" YGDSVAHLLSGLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0015969 (40.7%) GO:0005886 (44.1%) "GO:0016787 (11.9%) GO:0016301 (3.4%)" guanosine tetraphosphate metabolic process (40.7%) plasma membrane (44.1%) "hydrolase activity (11.9%) kinase activity (3.4%)" "IPR043519 (10.4%) IPR002912 (10%) IPR004095 (10%)" "Nucleotidyltransferase superfamily (10.4%) ACT domain (10%) TGS (10%)" VGFEAAAPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.5 (100%) argininosuccinate synthase (100%) "GO:0000050 (16.7%) GO:0000053 (16.7%) GO:0006526 (16.7%)" GO:0005737 (16.7%) "GO:0004055 (16.7%) GO:0005524 (16.7%)" "urea cycle (16.7%) argininosuccinate metabolic process (16.7%) L-arginine biosynthetic process (16.7%)" cytoplasm (16.7%) "argininosuccinate synthase activity (16.7%) ATP binding (16.7%)" "IPR001518 (14.4%) IPR018223 (14.4%) IPR023434 (14.4%)" "Argininosuccinate synthase (14.4%) Argininosuccinate synthase, conserved site (14.4%) Argininosuccinate synthase, type 1 subfamily (14.4%)" NNPLPAAYSR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25.1%) GO:0005886 (25.1%) "GO:0004222 (25.1%) GO:0046872 (24.6%)" protein processing (25.1%) plasma membrane (25.1%) "metalloendopeptidase activity (25.1%) metal ion binding (24.6%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20%)" LSDNDPDSYDEETLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.1 (97.2%) 6.3.1.5 (2.8%)" "NAD(+) synthase (glutamine-hydrolyzing) (97.2%) NAD(+) synthase (2.8%)" GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.8%) IPR003694 (14.8%) IPR014445 (14.8%)" "Carbon-nitrogen hydrolase (14.8%) NAD(+) synthetase (14.8%) Glutamine-dependent NAD(+) synthetase (14.8%)" DCGNADAEAAALKPGEALLLENLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" WLNDNQLPFEVNALSAHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.4.99.18 (92.3%) 4.1.1.21 (7.7%)" "5-(carboxyamino)imidazole ribonucleotide mutase (92.3%) phosphoribosylaminoimidazole carboxylase (7.7%)" GO:0006189 (33.3%) "GO:0016829 (33.3%) GO:0034023 (33.3%)" 'de novo' IMP biosynthetic process (33.3%) "lyase activity (33.3%) 5-(carboxyamino)imidazole ribonucleotide mutase activity (33.3%)" "IPR000031 (33.3%) IPR024694 (33.3%) IPR033747 (33.3%)" "PurE domain (33.3%) PurE, prokaryotic type (33.3%) Class I PurE (33.3%)" EESYDKLMGELEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.22 (100%) asparagine--tRNA ligase (100%) GO:0006421 (20.5%) GO:0005737 (19.2%) "GO:0005524 (20.5%) GO:0003676 (19.2%) GO:0004816 (19.2%)" asparaginyl-tRNA aminoacylation (20.5%) cytoplasm (19.2%) "ATP binding (20.5%) nucleic acid binding (19.2%) asparagine-tRNA ligase activity (19.2%)" "IPR004364 (15.4%) IPR004365 (14.4%) IPR004522 (14.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (15.4%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (14.4%) Asparagine-tRNA ligase (14.4%)" NTDLNSAFLTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NHDGGGPGLYTPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (32.6%) IPR033985 (32.6%) IPR012944 (30.2%)" "Tetratricopeptide-like helical domain superfamily (32.6%) SusD-like, N-terminal (32.6%) RagB/SusD domain (30.2%)" TPGLLAWSENGLGTGTTYMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" TDKPLEELVAGYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.38 (100%) N-acetyl-gamma-glutamyl-phosphate reductase (100%) GO:0006526 (20%) GO:0005737 (20%) "GO:0003942 (20%) GO:0051287 (20%) GO:0070401 (20%)" L-arginine biosynthetic process (20%) cytoplasm (20%) "N-acetyl-gamma-glutamyl-phosphate reductase activity (20%) NAD binding (20%) NADP+ binding (20%)" "IPR000534 (20.2%) IPR000706 (20.2%) IPR023013 (20.2%)" "Semialdehyde dehydrogenase, NAD-binding (20.2%) N-acetyl-gamma-glutamyl-phosphate reductase, type 1 (20.2%) N-acetyl-gamma-glutamyl-phosphate reductase, active site (20.2%)" SGGFEPLK root 2.1.1.14 (100%) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (100%) "GO:0009086 (27.2%) GO:0032259 (17.4%) GO:0006406 (0.1%)" "GO:0005737 (0.1%) GO:0005886 (0.1%) GO:0070390 (0.1%)" "GO:0003871 (27.2%) GO:0008270 (27.2%) GO:0008168 (0.1%)" "methionine biosynthetic process (27.2%) methylation (17.4%) mRNA export from nucleus (0.1%)" "cytoplasm (0.1%) plasma membrane (0.1%) transcription export complex 2 (0.1%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (27.2%) zinc ion binding (27.2%) methyltransferase activity (0.1%)" "IPR038071 (49.7%) IPR002629 (49.5%) IPR000522 (0.2%)" "UROD/MetE-like superfamily (49.7%) Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (49.5%) ABC transporter, permease protein, BtuC-like (0.2%)" YLDFAAK root "3.2.1.- (39.2%) 3.2.1.20 (16.9%) 3.2.1.22 (16.9%)" "Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (39.2%) alpha-glucosidase (16.9%) alpha-galactosidase (16.9%)" "GO:0051604 (2.4%) GO:0005975 (1.4%) GO:0000103 (0.2%)" "GO:0005829 (2.7%) GO:0005737 (0.7%) GO:0009279 (0.2%)" "GO:0030246 (46.8%) GO:0016787 (25.8%) GO:0016798 (6.2%)" "protein maturation (2.4%) carbohydrate metabolic process (1.4%) sulfate assimilation (0.2%)" "cytosol (2.7%) cytoplasm (0.7%) cell outer membrane (0.2%)" "carbohydrate binding (46.8%) hydrolase activity (25.8%) hydrolase activity, acting on glycosyl bonds (6.2%)" "IPR013785 (13%) IPR019563 (13%) IPR052720 (13%)" "Aldolase-type TIM barrel (13%) Glycosyl-hydrolase 97, catalytic domain (13%) Glycosyl Hydrolase Family 97 (13%)" FSNNPELANSGYNVPHTVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" LAEAYLNAAELLLETGGDANQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SVGLNALLTSLLYK root "GO:0051301 (19.8%) GO:0007059 (19.7%) GO:0007156 (0%)" "GO:0005886 (19.7%) GO:0016020 (0.2%)" "GO:0003677 (20.3%) GO:0005524 (20.3%) GO:0005509 (0%)" "cell division (19.8%) chromosome segregation (19.7%) homophilic cell-cell adhesion (0%)" "plasma membrane (19.7%) membrane (0.2%)" "DNA binding (20.3%) ATP binding (20.3%) calcium ion binding (0%)" "IPR002543 (12.5%) IPR050206 (12.5%) IPR027417 (12.5%)" "FtsK domain (12.5%) FtsK/SpoIIIE/SftA cell division and DNA translocation (12.5%) P-loop containing nucleoside triphosphate hydrolase (12.5%)" DNNFTWK root "6.1.1.10 (99.2%) 5.6.2.3 (0.5%) 5.6.2.4 (0.3%)" "methionine--tRNA ligase (99.2%) DNA 5'-3' helicase (0.5%) DNA 3'-5' helicase (0.3%)" "GO:0006431 (12.8%) GO:0006310 (0.1%) GO:0000723 (0.1%)" "GO:0005829 (12.8%) GO:0005634 (8.8%) GO:0016020 (0.3%)" "GO:0005524 (13%) GO:0046872 (12.9%) GO:0000049 (12.8%)" "methionyl-tRNA aminoacylation (12.8%) DNA recombination (0.1%) telomere maintenance (0.1%)" "cytosol (12.8%) nucleus (8.8%) membrane (0.3%)" "ATP binding (13%) metal ion binding (12.9%) tRNA binding (12.8%)" "IPR002547 (7.1%) IPR004495 (7.1%) IPR015413 (7.1%)" "tRNA-binding domain (7.1%) Methionyl-tRNA synthetase, beta subunit, C-terminal (7.1%) Methionyl/Leucyl tRNA synthetase (7.1%)" VLGQVPGESNVEVMKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0005412 (50%) plasma membrane (50%) D-glucose:sodium symporter activity (50%) "IPR001734 (52.9%) IPR038377 (47.1%)" "Sodium/solute symporter (52.9%) Sodium/glucose symporter superfamily (47.1%)" LPVYQDNTDNLR root GO:0005886 (51.9%) GO:0050660 (48.1%) plasma membrane (51.9%) flavin adenine dinucleotide binding (48.1%) "IPR000644 (13%) IPR044751 (13%) IPR005170 (12.7%)" "CBS domain (13%) Ion transporter-like, CBS domain (13%) Transporter-associated domain (12.7%)" YAGYVGGVSTMQGTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR008969 (100%) Carboxypeptidase-like, regulatory domain superfamily (100%) AADLLPLNWDNEYDGAATQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (35.1%) IPR011990 (32.4%) IPR012944 (32.4%)" "SusD-like, N-terminal (35.1%) Tetratricopeptide-like helical domain superfamily (32.4%) RagB/SusD domain (32.4%)" LLQFGEGNFLR Bacteria Bacteria "1.1.1.58 (99.8%) 1.-.-.- (0.2%)" "tagaturonate reductase (99.8%) Oxidoreductases (0.2%)" "GO:0019592 (21.5%) GO:0019698 (15.6%)" GO:0005829 (21.5%) "GO:0008926 (21.5%) GO:0009026 (19.6%) GO:0016491 (0.2%)" "mannitol catabolic process (21.5%) D-galacturonate catabolic process (15.6%)" cytosol (21.5%) "mannitol-1-phosphate 5-dehydrogenase activity (21.5%) tagaturonate reductase activity (19.6%) oxidoreductase activity (0.2%)" "IPR013131 (17.7%) IPR036291 (17.7%) IPR013118 (16.9%)" "Mannitol dehydrogenase, N-terminal (17.7%) NAD(P)-binding domain superfamily (17.7%) Mannitol dehydrogenase, C-terminal (16.9%)" ADMGHPAPFNLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (49.9%) "GO:0046556 (49.9%) GO:0016787 (0.3%)" L-arabinose metabolic process (49.9%) "alpha-L-arabinofuranosidase activity (49.9%) hydrolase activity (0.3%)" "IPR010720 (15.3%) IPR051563 (15.3%) IPR055235 (15.3%)" "Alpha-L-arabinofuranosidase, C-terminal (15.3%) Glycosyl Hydrolase Family 51 (15.3%) Alpha-L-arabinofuranosidase 1, catalytic domain (15.3%)" FTPTATPQLDEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR033408 (66.7%) IPR032187 (33.3%)" "Outer membrane protein SusF, N-terminal domain (66.7%) Outer membrane protein SusF/SusE-like, C-terminal (33.3%)" LEEQLGNNAAYGYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.7%) GO:0009986 (16.7%)" "GO:0000287 (16.7%) GO:0004634 (16.7%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.7%) cell surface (16.7%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%)" "IPR000941 (16.7%) IPR020809 (16.7%) IPR020810 (16.7%)" "Enolase (16.7%) Enolase, conserved site (16.7%) Enolase, C-terminal TIM barrel domain (16.7%)" SKGETFNGSWQAFAMNDYVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR011990 (32.8%) IPR033985 (32.8%)" "RagB/SusD domain (34.4%) Tetratricopeptide-like helical domain superfamily (32.8%) SusD-like, N-terminal (32.8%)" FMEGATDAKPQDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.7%) IPR051802 (19.7%) IPR001599 (19%)" "Macroglobulin domain (19.7%) Alpha-2-macroglobulin-like (19.7%) Alpha-2-macroglobulin (19%)" DTLEKENVSFDGLVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.2%) IPR004154 (11.2%) IPR004499 (11.2%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.2%) Anticodon-binding (11.2%) Proline-tRNA ligase, class IIa, archaeal-type (11.2%)" LGVTDMADALHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (20.6%) IPR012910 (20.6%) IPR039426 (20.6%)" "TonB-dependent receptor-like, beta-barrel (20.6%) TonB-dependent receptor, plug domain (20.6%) TonB-dependent receptor-like (20.6%)" VNLNLENLTVQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" FLGLLPAR root "2.7.7.38 (98%) 2.7.7.- (0.7%) 2.1.1.221 (0.5%)" "3-deoxy-manno-octulosonate cytidylyltransferase (98%) Nucleotidyltransferases (0.7%) tRNA (guanine(9)-N(1))-methyltransferase (0.5%)" "GO:0009103 (19.6%) GO:0033468 (19.4%) GO:0044281 (0.3%)" "GO:0005829 (20%) GO:0016020 (16.6%) GO:0005794 (0.2%)" "GO:0008690 (19.9%) GO:0008781 (0.6%) GO:0004252 (0.2%)" "lipopolysaccharide biosynthetic process (19.6%) CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process (19.4%) small molecule metabolic process (0.3%)" "cytosol (20%) membrane (16.6%) Golgi apparatus (0.2%)" "3-deoxy-manno-octulosonate cytidylyltransferase activity (19.9%) N-acylneuraminate cytidylyltransferase activity (0.6%) serine-type endopeptidase activity (0.2%)" "IPR003329 (30.3%) IPR029044 (30.1%) IPR004528 (29.5%)" "Acylneuraminate cytidylyltransferase (30.3%) Nucleotide-diphospho-sugar transferases (30.1%) 3-deoxy-D-manno-octulosonate cytidylyltransferase (29.5%)" LASLGLYPAVDPLGSTSR Pseudomonadati Bacteria Pseudomonadati 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0045259 (22.2%) GO:0005886 (20.8%)" "GO:0005524 (22.2%) GO:0046933 (22.2%) GO:0016787 (12.5%)" "proton-transporting ATP synthase complex (22.2%) plasma membrane (20.8%)" "ATP binding (22.2%) proton-transporting ATP synthase activity, rotational mechanism (22.2%) hydrolase activity (12.5%)" "IPR000194 (10.3%) IPR020003 (10.3%) IPR024034 (10.3%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.3%) ATPase, alpha/beta subunit, nucleotide-binding domain, active site (10.3%) ATPase, F1/V1 complex, beta/alpha subunit, C-terminal (10.3%)" YGLPELAHELVDELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0005737 (12.5%) GO:0070062 (12.5%) GO:1990742 (12.5%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "cytoplasm (12.5%) extracellular exosome (12.5%) microvesicle (12.5%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.7%) IPR004154 (11.7%) IPR006195 (11.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.7%) Anticodon-binding (11.7%) Aminoacyl-tRNA synthetase, class II (11.7%)" GVCLHHDLGPLGAAENK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.23 (50%) 3.2.1.31 (50%)" "beta-galactosidase (50%) beta-glucuronidase (50%)" GO:0005975 (50%) "GO:0004553 (48%) GO:0004565 (1%) GO:0004566 (1%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48%) beta-galactosidase activity (1%) beta-glucuronidase activity (1%)" "IPR006103 (9.5%) IPR051913 (9.5%) IPR006104 (9.3%)" "Glycoside hydrolase family 2, catalytic domain (9.5%) Glycosyl Hydrolase 2 Domain-Containing Protein (9.5%) Glycosyl hydrolases family 2, sugar binding domain (9.3%)" ALAEELVNLTVK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR000206 (20%) IPR008932 (20%) IPR013823 (20%)" "Large ribosomal subunit protein bL12 (20%) Large ribosomal subunit protein bL12, oligomerization (20%) Large ribosomal subunit protein bL12, C-terminal (20%)" DNMFPVPPLFK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.7%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.7%)" "IPR004733 (20.1%) IPR010918 (20.1%) IPR036676 (20.1%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20.1%) PurM-like, C-terminal domain (20.1%) PurM-like, C-terminal domain superfamily (20.1%)" DNASNEALAEQEAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25.2%) "GO:0005525 (25.2%) GO:0015093 (25.2%) GO:0046914 (24.4%)" plasma membrane (25.2%) "GTP binding (25.2%) ferrous iron transmembrane transporter activity (25.2%) transition metal ion binding (24.4%)" "IPR005225 (9.4%) IPR030389 (9.4%) IPR050860 (9.4%)" "Small GTP-binding domain (9.4%) FeoB-type guanine nucleotide-binding (G) domain (9.4%) Fe(2+) Transporter FeoB GTPase (9.4%)" TTLALHALAEAQK root "GO:0006281 (12.7%) GO:0006310 (12.7%) GO:0009432 (11.8%)" "GO:0005829 (12.5%) GO:0005737 (0%) GO:0016020 (0%)" "GO:0003697 (12.7%) GO:0005524 (12.7%) GO:0140664 (12.7%)" "DNA repair (12.7%) DNA recombination (12.7%) SOS response (11.8%)" "cytosol (12.5%) cytoplasm (0%) membrane (0%)" "single-stranded DNA binding (12.7%) ATP binding (12.7%) ATP-dependent DNA damage sensor activity (12.7%)" "IPR013765 (11.4%) IPR020588 (11.4%) IPR049428 (11.4%)" "DNA recombination and repair protein RecA (11.4%) DNA recombination and repair protein RecA-like, ATP-binding domain (11.4%) RecA-like, N-terminal (11.4%)" VANAPLVVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.7%) IPR033985 (35.7%) IPR011990 (28.6%)" "RagB/SusD domain (35.7%) SusD-like, N-terminal (35.7%) Tetratricopeptide-like helical domain superfamily (28.6%)" DLWETYMPAFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.2.1.21 (66.7%) 3.2.1.37 (33.3%)" "beta-glucosidase (66.7%) xylan 1,4-beta-xylosidase (33.3%)" "GO:0031222 (24.7%) GO:0045493 (24.7%)" "GO:0009044 (24.7%) GO:0046556 (24.7%) GO:0008422 (1.1%)" "arabinan catabolic process (24.7%) xylan catabolic process (24.7%)" "xylan 1,4-beta-xylosidase activity (24.7%) alpha-L-arabinofuranosidase activity (24.7%) beta-glucosidase activity (1.1%)" "IPR001764 (9.5%) IPR044993 (9.5%) IPR002772 (9.1%)" "Glycoside hydrolase, family 3, N-terminal (9.5%) Beta-D-xylosidase (9.5%) Glycoside hydrolase family 3 C-terminal domain (9.1%)" GCEGCLNVDVLHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016747 (100%) acyltransferase activity, transferring groups other than amino-acyl groups (100%) "IPR016181 (51.5%) IPR000182 (39.4%) IPR007569 (3%)" "Acyl-CoA N-acyltransferase (51.5%) GNAT domain (39.4%) Domain of unknown function DUF559 (3%)" NCANVLADFNVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (25%) GO:0005737 (25%) "GO:0004814 (25%) GO:0005524 (25%)" arginyl-tRNA aminoacylation (25%) cytoplasm (25%) "arginine-tRNA ligase activity (25%) ATP binding (25%)" "IPR001278 (12.9%) IPR001412 (12.9%) IPR005148 (12.9%)" "Arginine-tRNA ligase (12.9%) Aminoacyl-tRNA synthetase, class I, conserved site (12.9%) Arginyl tRNA synthetase N-terminal domain (12.9%)" AFYPTTEGTGSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR006530 (16.3%) IPR050708 (16.3%) IPR031325 (15.7%)" "YD repeat (16.3%) Type VI secretion system VgrG/RHS (16.3%) RHS repeat (15.7%)" QYQELLGVPVDMNEVFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (25%) IPR018485 (25%) IPR043129 (25%)" "Carbohydrate kinase FGGY, N-terminal (25%) Carbohydrate kinase FGGY, C-terminal (25%) ATPase, nucleotide binding domain (25%)" NEYYGLNALYETWYNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR012944 (33.8%) IPR033985 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) RagB/SusD domain (33.8%) SusD-like, N-terminal (32.4%)" VDALGGYEWFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006508 (9.3%) "GO:0009279 (20.3%) GO:1990281 (20.3%)" "GO:0015288 (20.3%) GO:0015562 (20.3%) GO:0008233 (9.3%)" proteolysis (9.3%) "cell outer membrane (20.3%) efflux pump complex (20.3%)" "porin activity (20.3%) efflux transmembrane transporter activity (20.3%) peptidase activity (9.3%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LATALGNAHFWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (36.4%) IPR033985 (36.4%) IPR011990 (27.3%)" "RagB/SusD domain (36.4%) SusD-like, N-terminal (36.4%) Tetratricopeptide-like helical domain superfamily (27.3%)" VLSHVEGNFQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.8%) GO:0009279 (42.3%) GO:0015344 (28.8%) siderophore transmembrane transport (28.8%) cell outer membrane (42.3%) siderophore uptake transmembrane transporter activity (28.8%) "IPR000531 (43.1%) IPR036942 (33.8%) IPR039426 (23.1%)" "TonB-dependent receptor-like, beta-barrel (43.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (33.8%) TonB-dependent receptor-like (23.1%)" DGLFLTSWERPLNLLDVATEPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (76.5%) IPR008160 (23.5%)" "Domain of unknown function DUF4988 (76.5%) Collagen triple helix repeat (23.5%)" SWLDMDLQPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0004825 (16.7%) GO:0005524 (16.7%) GO:0000049 (16.6%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "methionine-tRNA ligase activity (16.7%) ATP binding (16.7%) tRNA binding (16.6%)" "IPR015413 (8.4%) IPR023458 (8.4%) IPR001412 (8.3%)" "Methionyl/Leucyl tRNA synthetase (8.4%) Methionine-tRNA ligase, type 1 (8.4%) Aminoacyl-tRNA synthetase, class I, conserved site (8.3%)" LANPFNGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) IPR013320 (100%) Concanavalin A-like lectin/glucanase domain superfamily (100%) DVTGSLASVNSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" WAGGMLTNFPTLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" QLVHVSFGGEELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016788 (100%) hydrolase activity, acting on ester bonds (100%) "IPR013830 (33.3%) IPR036514 (33.3%) IPR053140 (33.3%)" "SGNH hydrolase-type esterase domain (33.3%) SGNH hydrolase superfamily (33.3%) GDSL lipase Rv0518-like (33.3%)" VCAEMDHAADWTQQYHYGALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (51.9%) IPR032466 (48.1%)" "Uronate isomerase (51.9%) Metal-dependent hydrolase (48.1%)" EQGQLKPFSVLLFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" NPAWFAENFNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" CLGSLEELYAELEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" SLETLDQLLTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" SYGLLPVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (13.6%) GO:0006221 (13.4%) GO:0006526 (13.4%)" GO:0005737 (13.6%) "GO:0004088 (13.6%) GO:0005524 (13.6%) GO:0046872 (13.6%)" "glutamine metabolic process (13.6%) pyrimidine nucleotide biosynthetic process (13.4%) L-arginine biosynthetic process (13.4%)" cytoplasm (13.6%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.6%) ATP binding (13.6%) metal ion binding (13.6%)" "IPR005480 (10.4%) IPR005479 (10.2%) IPR011761 (10.2%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.4%) Carbamoyl phosphate synthase, ATP-binding domain (10.2%) ATP-grasp fold (10.2%)" GNSAKDENVMLVSGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005576 (50%) GO:0005737 (50%)" "extracellular region (50%) cytoplasm (50%)" "IPR006530 (16.4%) IPR050708 (16.4%) IPR031325 (15.6%)" "YD repeat (16.4%) Type VI secretion system VgrG/RHS (16.4%) RHS repeat (15.6%)" DGETVTLKGDYLLDYENAHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (28.9%) IPR014756 (28.9%) IPR040475 (28.9%)" "Immunoglobulin-like fold (28.9%) Immunoglobulin E-set (28.9%) Surface glycan-binding protein B, xyloglucan binding domain (28.9%)" LNSYQAVAAFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YNDVWNNLYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NSGLEFELGYK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" ALPLLQELVTMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (34.4%) IPR039565 (34.4%) IPR011990 (31.3%)" "Outer membrane protein assembly factor BamD (34.4%) Outer membrane lipoprotein BamD-like (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" FVDAQTYAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" TEVNHPASGLTSFTYDALGNVLTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.6%) GO:0005737 (48.6%)" GO:0016787 (2.7%) "extracellular region (48.6%) cytoplasm (48.6%)" hydrolase activity (2.7%) "IPR006530 (17.5%) IPR050708 (17.5%) IPR031325 (17%)" "YD repeat (17.5%) Type VI secretion system VgrG/RHS (17.5%) RHS repeat (17%)" NLATQLEHMLAYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (21.1%) GO:0022627 (21.1%) "GO:0003735 (21.1%) GO:0019843 (21.1%) GO:0003729 (15.8%)" translation (21.1%) cytosolic small ribosomal subunit (21.1%) "structural constituent of ribosome (21.1%) rRNA binding (21.1%) mRNA binding (15.8%)" "IPR001351 (11.1%) IPR004044 (11.1%) IPR004087 (11.1%)" "Small ribosomal subunit protein uS3, C-terminal (11.1%) K Homology domain, type 2 (11.1%) K Homology domain (11.1%)" LTAADVVYK root GO:0043291 (100%) RAVE complex (100%) "IPR025634 (78.4%) IPR028241 (21.6%)" "Protein of unknown function DUF4292 (78.4%) RAVE subunit 2/Rogdi (21.6%)" MTHQVDLGNFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.5%) IPR012944 (33.6%) IPR011990 (31.8%)" "SusD-like, N-terminal (34.5%) RagB/SusD domain (33.6%) Tetratricopeptide-like helical domain superfamily (31.8%)" LGESDWLQLDQDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002539 (33.3%) IPR029069 (33.3%) IPR039375 (33.3%)" "MaoC-like dehydratase domain (33.3%) HotDog domain superfamily (33.3%) Nodulation protein N-like (33.3%)" VFLGAQSGVPGSLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.3.1.191 (98.4%) 2.3.1.- (1.6%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (98.4%) Transferring groups other than amino-acyl groups (1.6%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (22.2%) IPR007691 (22.2%) IPR011004 (22.2%)" "Hexapeptide repeat (22.2%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (22.2%) Trimeric LpxA-like superfamily (22.2%)" EGLCGMCSLYLNGTPHGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.99.1 (100%) Deleted entry (100%) "GO:0009060 (23.9%) GO:0022904 (23.9%)" "GO:0009055 (23.9%) GO:0051537 (23.9%) GO:0016491 (4.5%)" "aerobic respiration (23.9%) respiratory electron transport chain (23.9%)" "electron transfer activity (23.9%) 2 iron, 2 sulfur cluster binding (23.9%) oxidoreductase activity (4.5%)" "IPR006058 (13.6%) IPR009051 (13.6%) IPR012675 (13.6%)" "2Fe-2S ferredoxin, iron-sulphur binding site (13.6%) Alpha-helical ferredoxin (13.6%) Beta-grasp domain superfamily (13.6%)" LQLFLPLLGTEVGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR025634 (100%) Protein of unknown function DUF4292 (100%) YGFGFNVLPSQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.5%) IPR004659 (25.5%) IPR019307 (25.5%)" "S1 domain (25.5%) Ribonuclease E/G (25.5%) RNA-binding protein AU-1/Ribonuclease E/G (25.5%)" VWNPVLR root "3.1.3.48 (73.3%) 5.6.2.4 (22.6%) 5.4.99.- (1.4%)" "protein-tyrosine-phosphatase (73.3%) DNA 3'-5' helicase (22.6%) Transferring other groups (1.4%)" "GO:0006260 (3.9%) GO:0006281 (3.9%) GO:0006310 (3.8%)" "GO:0005737 (16.5%) GO:0009898 (12.6%) GO:0005856 (10.5%)" "GO:0004725 (12.7%) GO:0005524 (4.2%) GO:0003677 (3.9%)" "DNA replication (3.9%) DNA repair (3.9%) DNA recombination (3.8%)" "cytoplasm (16.5%) cytoplasmic side of plasma membrane (12.6%) cytoskeleton (10.5%)" "protein tyrosine phosphatase activity (12.7%) ATP binding (4.2%) DNA binding (3.9%)" "IPR018980 (4.8%) IPR001478 (4.7%) IPR000299 (4.6%)" "FERM, C-terminal PH-like domain (4.8%) PDZ domain (4.7%) FERM domain (4.6%)" RLPLLDALK root 6.1.1.6 (100%) lysine--tRNA ligase (100%) "GO:0006430 (16.6%) GO:0000271 (0.1%)" "GO:0005829 (16.6%) GO:0016020 (0.4%) GO:0005737 (0.1%)" "GO:0000049 (16.6%) GO:0004824 (16.6%) GO:0005524 (16.6%)" "lysyl-tRNA aminoacylation (16.6%) polysaccharide biosynthetic process (0.1%)" "cytosol (16.6%) membrane (0.4%) cytoplasm (0.1%)" "tRNA binding (16.6%) lysine-tRNA ligase activity (16.6%) ATP binding (16.6%)" "IPR004364 (11.9%) IPR006195 (11.9%) IPR018149 (11.8%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (11.9%) Aminoacyl-tRNA synthetase, class II (11.9%) Lysyl-tRNA synthetase, class II, C-terminal (11.8%)" LGEAGEFDYSGSQALK root "6.3.5.5 (84.1%) 6.3.4.16 (15.6%) 6.3.4.6 (0.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (84.1%) carbamoyl-phosphate synthase (ammonia) (15.6%) urea carboxylase (0.3%)" "GO:0006541 (13.8%) GO:0006526 (11.1%) GO:0006221 (10.9%)" "GO:0005737 (13.7%) GO:0005951 (0.1%) GO:0005829 (0%)" "GO:0004088 (13.8%) GO:0005524 (13.8%) GO:0046872 (13.8%)" "glutamine metabolic process (13.8%) L-arginine biosynthetic process (11.1%) pyrimidine nucleotide biosynthetic process (10.9%)" "cytoplasm (13.7%) carbamoyl-phosphate synthase complex (0.1%) cytosol (0%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.8%) ATP binding (13.8%) metal ion binding (13.8%)" "IPR016185 (10.2%) IPR005483 (10.2%) IPR005479 (10.1%)" "Pre-ATP-grasp domain superfamily (10.2%) Carbamoyl phosphate synthase, CPSase domain (10.2%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" AVLLNALDFMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.7%) GO:0009090 (17.7%) GO:0009088 (11.6%)" GO:0005829 (17.7%) "GO:0004072 (17.7%) GO:0005524 (17.7%)" "lysine biosynthetic process via diaminopimelate (17.7%) homoserine biosynthetic process (17.7%) threonine biosynthetic process (11.6%)" cytosol (17.7%) "aspartate kinase activity (17.7%) ATP binding (17.7%)" "IPR001048 (14.1%) IPR001341 (14.1%) IPR005260 (14.1%)" "Aspartate/glutamate/uridylate kinase (14.1%) Aspartate kinase (14.1%) Aspartate kinase, monofunctional class (14.1%)" YYLLFSAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.37 (50%) 3.2.1.55 (50%)" "xylan 1,4-beta-xylosidase (50%) non-reducing end alpha-L-arabinofuranosidase (50%)" "GO:0045493 (47.9%) GO:0005975 (1.4%)" "GO:0004553 (47.9%) GO:0009044 (1.4%) GO:0046556 (1.4%)" "xylan catabolic process (47.9%) carbohydrate metabolic process (1.4%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (47.9%) xylan 1,4-beta-xylosidase activity (1.4%) alpha-L-arabinofuranosidase activity (1.4%)" "IPR006710 (32.7%) IPR052176 (32.7%) IPR023296 (31.8%)" "Glycoside hydrolase, family 43 (32.7%) Glycosyl Hydrolase Family 43 Enzymes (32.7%) Glycosyl hydrolase, five-bladed beta-propeller domain superfamily (31.8%)" TSAPYFR root "2.7.13.3 (66.7%) 1.1.1.94 (16.7%) 2.4.2.- (16.7%)" "histidine kinase (66.7%) glycerol-3-phosphate dehydrogenase [NAD(P)(+)] (16.7%) Pentosyltransferases (16.7%)" "GO:0005975 (2.5%) GO:0006650 (2.5%) GO:0008654 (2.5%)" "GO:0005886 (12.5%) GO:0016020 (10%) GO:0005829 (2.5%)" "GO:0000155 (10%) GO:0009927 (10%) GO:0005524 (5%)" "carbohydrate metabolic process (2.5%) glycerophospholipid metabolic process (2.5%) phospholipid biosynthetic process (2.5%)" "plasma membrane (12.5%) membrane (10%) cytosol (2.5%)" "phosphorelay sensor kinase activity (10%) histidine phosphotransfer kinase activity (10%) ATP binding (5%)" "IPR046111 (40%) IPR001789 (3.5%) IPR003594 (3.5%)" "Protein of unknown function DUF6048 (40%) Signal transduction response regulator, receiver domain (3.5%) Histidine kinase/HSP90-like ATPase domain (3.5%)" LVENGAGYFLNQSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR011050 (36.4%) IPR033427 (36.4%) IPR012334 (27.3%)" "Pectin lyase fold/virulence factor (36.4%) Domain of unknown function DUF5123 (36.4%) Pectin lyase fold (27.3%)" ALEAFFLDEAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.11 (100%) serine--tRNA ligase (100%) "GO:0006434 (24.7%) GO:0006412 (0.3%)" GO:0005737 (24.7%) "GO:0004828 (24.7%) GO:0005524 (24.7%) GO:0000166 (0.3%)" "seryl-tRNA aminoacylation (24.7%) translation (0.3%)" cytoplasm (24.7%) "serine-tRNA ligase activity (24.7%) ATP binding (24.7%) nucleotide binding (0.3%)" "IPR010978 (14.3%) IPR015866 (14.3%) IPR042103 (14.3%)" "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm (14.3%) Serine-tRNA synthetase, type1, N-terminal (14.3%) Serine-tRNA synthetase, type1, N-terminal domain superfamily (14.3%)" VTAPLLYSYDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" QLANLPVSNVSEAMTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (27.6%) GO:0009279 (72.4%) iron ion transport (27.6%) cell outer membrane (72.4%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EYGMLDNVLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.21.92 (100%) endopeptidase Clp (100%) GO:0006515 (16.7%) "GO:0005737 (16.7%) GO:0009368 (16.7%)" "GO:0004176 (16.7%) GO:0004252 (16.7%) GO:0051117 (16.7%)" protein quality control for misfolded or incompletely synthesized proteins (16.7%) "cytoplasm (16.7%) endopeptidase Clp complex (16.7%)" "ATP-dependent peptidase activity (16.7%) serine-type endopeptidase activity (16.7%) ATPase binding (16.7%)" "IPR001907 (26.3%) IPR023562 (26.3%) IPR029045 (26.3%)" "ATP-dependent Clp protease proteolytic subunit (26.3%) Clp protease proteolytic subunit /Translocation-enhancing protein TepA (26.3%) ClpP/crotonase-like domain superfamily (26.3%)" VSQEFDASDDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.2%) GO:0009341 (25.2%) "GO:0004565 (25.2%) GO:0030246 (24.3%)" lactose catabolic process (25.2%) beta-galactosidase complex (25.2%) "beta-galactosidase activity (25.2%) carbohydrate binding (24.3%)" "IPR004199 (7.3%) IPR006102 (7.3%) IPR006103 (7.3%)" "Beta galactosidase small chain/ domain 5 (7.3%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.3%) Glycoside hydrolase family 2, catalytic domain (7.3%)" AQPLTGLDGDHLGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.9 (97%) 1.6.5.- (3%)" "NADH:ubiquinone reductase (non-electrogenic) (97%) With a quinone or similar compound as acceptor (3%)" GO:0003954 (100%) NADH dehydrogenase activity (100%) "IPR023753 (25.6%) IPR045024 (25.6%) IPR054585 (24.8%)" "FAD/NAD(P)-binding domain (25.6%) Alternative NADH dehydrogenase (25.6%) External alternative NADH-ubiquinone oxidoreductase-like, C-terminal domain (24.8%)" MNLNLEDVTAAASTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0000271 (25%) "GO:0016616 (25%) GO:0016628 (25%) GO:0051287 (25%)" polysaccharide biosynthetic process (25%) "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (25%) oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor (25%) NAD binding (25%)" "IPR001732 (12.7%) IPR014026 (12.7%) IPR014027 (12.7%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (12.7%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (12.7%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (12.7%)" NAWETAVYCADQLASLGYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TDGLNDKFLAQADGSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.7%) IPR012910 (20.7%) IPR039426 (20.7%)" "TonB-dependent receptor-like, beta-barrel (20.7%) TonB-dependent receptor, plug domain (20.7%) TonB-dependent receptor-like (20.7%)" VLVLNCGSSSLK root "2.7.2.1 (75.7%) 2.7.2.15 (24%) 2.7.2.7 (0.1%)" "acetate kinase (75.7%) propionate kinase (24%) butyrate kinase (0.1%)" "GO:0006083 (16%) GO:0006085 (11.8%) GO:0070689 (3.9%)" "GO:0005829 (12.7%) GO:0005737 (3.3%) GO:0016020 (0%)" "GO:0005524 (16.1%) GO:0008776 (16%) GO:0000287 (11.8%)" "acetate metabolic process (16%) acetyl-CoA biosynthetic process (11.8%) L-threonine catabolic process to propionate (3.9%)" "cytosol (12.7%) cytoplasm (3.3%) membrane (0%)" "ATP binding (16.1%) acetate kinase activity (16%) magnesium ion binding (11.8%)" "IPR023865 (23.6%) IPR000890 (23.6%) IPR043129 (23.6%)" "Aliphatic acid kinase, short-chain, conserved site (23.6%) Aliphatic acid kinase, short-chain (23.6%) ATPase, nucleotide binding domain (23.6%)" NYVVQFENPVEPEQLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" KLDQALDGVEEMSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0000917 (14.3%) GO:0043093 (14.3%) GO:0051258 (14.3%)" "GO:0005737 (14.3%) GO:0032153 (14.3%)" "GO:0003924 (14.3%) GO:0005525 (14.3%)" "division septum assembly (14.3%) FtsZ-dependent cytokinesis (14.3%) protein polymerization (14.3%)" "cytoplasm (14.3%) cell division site (14.3%)" "GTPase activity (14.3%) GTP binding (14.3%)" "IPR000158 (11.3%) IPR003008 (11.3%) IPR018316 (11.3%)" "Cell division protein FtsZ (11.3%) Tubulin/FtsZ, GTPase domain (11.3%) Tubulin/FtsZ, 2-layer sandwich domain (11.3%)" GDFQGVLDKLDYLK root 3.2.1.1 (100%) alpha-amylase (100%) GO:0005975 (68.8%) GO:0016020 (3.6%) "GO:0016787 (17.9%) GO:0004556 (3.6%) GO:0005509 (3.6%)" carbohydrate metabolic process (68.8%) membrane (3.6%) "hydrolase activity (17.9%) alpha-amylase activity (3.6%) calcium ion binding (3.6%)" "IPR006047 (24.9%) IPR017853 (24.3%) IPR013783 (21.7%)" "Glycosyl hydrolase family 13, catalytic domain (24.9%) Glycoside hydrolase superfamily (24.3%) Immunoglobulin-like fold (21.7%)" AYYDLEHLWEDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0017148 (20%) GO:0042256 (20%) GO:0090071 (20%)" GO:0005737 (20%) GO:0043023 (20%) "negative regulation of translation (20%) cytosolic ribosome assembly (20%) negative regulation of ribosome biogenesis (20%)" cytoplasm (20%) ribosomal large subunit binding (20%) "IPR004394 (53.8%) IPR043519 (46.2%)" "Protein Iojap/ribosomal silencing factor RsfS (53.8%) Nucleotidyltransferase superfamily (46.2%)" LAEAAGACAVMALER root "4.3.3.6 (99.6%) 4.-.-.- (0.4%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (99.6%) Lyases (0.4%)" "GO:0006520 (24.7%) GO:0008615 (24.7%) GO:0042823 (24.7%)" "GO:0016020 (0.2%) GO:0005737 (0.1%) GO:0005829 (0.1%)" "GO:0036381 (20.7%) GO:0016843 (4.3%) GO:0016740 (0.2%)" "amino acid metabolic process (24.7%) pyridoxine biosynthetic process (24.7%) pyridoxal phosphate biosynthetic process (24.7%)" "membrane (0.2%) cytoplasm (0.1%) cytosol (0.1%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (20.7%) amine-lyase activity (4.3%) transferase activity (0.2%)" "IPR001852 (25%) IPR013785 (25%) IPR033755 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Aldolase-type TIM barrel (25%) PdxS/SNZ N-terminal domain (25%)" YQLQLVLPAEAGEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" GKEFPFEDTTVLLPEQADTYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009100 (100%) glycoprotein metabolic process (100%) "IPR007074 (50%) IPR052942 (46.7%) IPR043519 (3.3%)" "LicD/FKTN/FKRP, nucleotidyltransferase domain (50%) Lipopolysaccharide cholinephosphotransferase (46.7%) Nucleotidyltransferase superfamily (3.3%)" NTFNPDAPGTLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.3 (51.2%) 2.7.2.4 (48.8%)" "homoserine dehydrogenase (51.2%) aspartate kinase (48.8%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" AYDVPYFSLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.1.3.62 (50%) 3.1.3.80 (50%)" "multiple inositol-polyphosphate phosphatase (50%) 2,3-bisphosphoglycerate 3-phosphatase (50%)" GO:0016020 (51.4%) GO:0016787 (48.6%) membrane (51.4%) hydrolase activity (48.6%) "IPR000560 (50.7%) IPR029033 (49.3%)" "Histidine phosphatase superfamily, clade-2 (50.7%) Histidine phosphatase superfamily (49.3%)" MDTYPYADRDAMAHWMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" TYPNLLGNESAR Pseudomonadati Bacteria Pseudomonadati "3.2.1.22 (41%) 3.2.1.20 (22.9%) 3.2.1.3 (22.9%)" "alpha-galactosidase (41%) alpha-glucosidase (22.9%) glucan 1,4-alpha-glucosidase (22.9%)" GO:0005983 (0.1%) "GO:0005886 (0.1%) GO:0016020 (0.1%) GO:0042597 (0.1%)" "GO:0030246 (56.8%) GO:0016787 (35.8%) GO:0004557 (2.9%)" starch catabolic process (0.1%) "plasma membrane (0.1%) membrane (0.1%) periplasmic space (0.1%)" "carbohydrate binding (56.8%) hydrolase activity (35.8%) alpha-galactosidase activity (2.9%)" "IPR019563 (14.4%) IPR052720 (14.4%) IPR013785 (14.3%)" "Glycosyl-hydrolase 97, catalytic domain (14.4%) Glycosyl Hydrolase Family 97 (14.4%) Aldolase-type TIM barrel (14.3%)" AMEEGKWDLSLVDPEELAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (21.4%) GO:0045259 (21.4%)" "GO:0005524 (21.4%) GO:0046933 (21.4%) GO:0016787 (14.3%)" "plasma membrane (21.4%) proton-transporting ATP synthase complex (21.4%)" "ATP binding (21.4%) proton-transporting ATP synthase activity, rotational mechanism (21.4%) hydrolase activity (14.3%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" KAAYLNSGTWAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20.2%) GO:0008615 (19.3%)" GO:0005737 (20.2%) "GO:0004648 (20.2%) GO:0030170 (20.2%)" "L-serine biosynthetic process (20.2%) pyridoxine biosynthetic process (19.3%)" cytoplasm (20.2%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20.2%) pyridoxal phosphate binding (20.2%)" "IPR000192 (20.9%) IPR022278 (20.9%) IPR015421 (20%)" "Aminotransferase class V domain (20.9%) Phosphoserine aminotransferase (20.9%) Pyridoxal phosphate-dependent transferase, major domain (20%)" GSADTYTDWWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YVVDMLR root "3.4.23.36 (55.3%) 5.4.4.2 (27.7%) 2.7.11.1 (4.3%)" "signal peptidase II (55.3%) isochorismate synthase (27.7%) non-specific serine/threonine protein kinase (4.3%)" "GO:0006412 (9.3%) GO:0006508 (5.5%) GO:0009697 (2%)" "GO:0022625 (9.3%) GO:0005886 (7.5%) GO:0016020 (7.5%)" "GO:0003735 (9.3%) GO:0019843 (9.3%) GO:0004190 (5.5%)" "translation (9.3%) proteolysis (5.5%) salicylic acid biosynthetic process (2%)" "cytosolic large ribosomal subunit (9.3%) plasma membrane (7.5%) membrane (7.5%)" "structural constituent of ribosome (9.3%) rRNA binding (9.3%) aspartic-type endopeptidase activity (5.5%)" "IPR001063 (9%) IPR005727 (9%) IPR036394 (9%)" "Large ribosomal subunit protein uL22 (9%) Large ribosomal subunit protein uL22, bacterial/chloroplast-type (9%) Ribosomal protein uL22 superfamily (9%)" VLDFLPFTHLFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (33.9%) IPR020845 (33.9%) IPR042099 (32.1%)" "AMP-dependent synthetase/ligase domain (33.9%) AMP-binding, conserved site (33.9%) ANL, N-terminal domain (32.1%)" YLLPDSLETLK Pseudomonadati Bacteria Pseudomonadati 2.8.1.10 (100%) thiazole synthase (100%) "GO:0009229 (29.8%) GO:0009228 (8.8%)" "GO:0005737 (29.8%) GO:0016020 (0.5%) GO:1902508 (0.5%)" "GO:1990107 (22.4%) GO:0016783 (8.3%)" "thiamine diphosphate biosynthetic process (29.8%) thiamine biosynthetic process (8.8%)" "cytoplasm (29.8%) membrane (0.5%) 2-iminoacetate synthase complex (0.5%)" "thiazole synthase activity (22.4%) sulfurtransferase activity (8.3%)" "IPR008867 (33.5%) IPR033983 (33.5%) IPR013785 (33%)" "Thiazole synthase (33.5%) Thiazole synthase ThiG (33.5%) Aldolase-type TIM barrel (33%)" QTMLFGGLESVVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.6%) GO:0009328 (16.6%) "GO:0000049 (16.6%) GO:0000287 (16.6%) GO:0004826 (16.6%)" phenylalanyl-tRNA aminoacylation (16.6%) phenylalanine-tRNA ligase complex (16.6%) "tRNA binding (16.6%) magnesium ion binding (16.6%) phenylalanine-tRNA ligase activity (16.6%)" "IPR041616 (8%) IPR002547 (7.7%) IPR004532 (7.7%)" "Phenylalanyl tRNA synthetase beta chain, core domain (8%) tRNA-binding domain (7.7%) Phenylalanine-tRNA ligase, class IIc, beta subunit, bacterial type (7.7%)" LNPNATLGR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "GO:0006811 (9.7%) GO:0015889 (9.7%) GO:0044718 (9.1%)" GO:0009279 (60.6%) GO:0015344 (9.1%) "monoatomic ion transport (9.7%) cobalamin transport (9.7%) siderophore transmembrane transport (9.1%)" cell outer membrane (60.6%) siderophore uptake transmembrane transporter activity (9.1%) "IPR012910 (14%) IPR023997 (14%) IPR037066 (14%)" "TonB-dependent receptor, plug domain (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%) TonB-dependent receptor, plug domain superfamily (14%)" FLLDTLK root "6.1.1.21 (16.4%) 2.8.1.12 (14%) 3.1.3.76 (14%)" "histidine--tRNA ligase (16.4%) molybdopterin synthase (14%) lipid-phosphate phosphatase (14%)" "GO:0000467 (1.3%) GO:0006777 (1.3%) GO:0009636 (1.2%)" "GO:0016020 (6.3%) GO:0005737 (3.2%) GO:0005829 (2.2%)" "GO:0030246 (3.3%) GO:0005524 (2.4%) GO:0046872 (2.3%)" "exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (1.3%) Mo-molybdopterin cofactor biosynthetic process (1.3%) response to toxic substance (1.2%)" "membrane (6.3%) cytoplasm (3.2%) cytosol (2.2%)" "carbohydrate binding (3.3%) ATP binding (2.4%) metal ion binding (2.3%)" "IPR016186 (3.1%) IPR016187 (3.1%) IPR050111 (2.7%)" "C-type lectin-like/link domain superfamily (3.1%) C-type lectin fold (3.1%) C-type lectin and snaclec domain-containing protein (2.7%)" FGFEVTR root "7.1.1.- (71.8%) 1.6.5.11 (6.8%) 3.2.1.20 (4.9%)" "Hydron translocation or charge separation linked to oxidoreductase reactions (71.8%) Transferred entry: 1.6.5.9 (6.8%) alpha-glucosidase (4.9%)" "GO:0009060 (10.1%) GO:0015990 (10.1%) GO:0005975 (0.7%)" "GO:0045271 (10.1%) GO:0005886 (9.9%) GO:0016020 (1.1%)" "GO:0008137 (10.1%) GO:0048038 (10.1%) GO:0051539 (10.1%)" "aerobic respiration (10.1%) electron transport coupled proton transport (10.1%) carbohydrate metabolic process (0.7%)" "respiratory chain complex I (10.1%) plasma membrane (9.9%) membrane (1.1%)" "NADH dehydrogenase (ubiquinone) activity (10.1%) quinone binding (10.1%) 4 iron, 4 sulfur cluster binding (10.1%)" "IPR006137 (25.2%) IPR006138 (25.2%) IPR000182 (4.8%)" "NADH:ubiquinone oxidoreductase-like, 20kDa subunit (25.2%) NADH-ubiquinone oxidoreductase, 20 Kd subunit (25.2%) GNAT domain (4.8%)" KYNEAVQNYNQTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" CLFDHLDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.3.11 (100%) fructose-bisphosphatase (100%) GO:0006094 (50%) GO:0042132 (50%) gluconeogenesis (50%) fructose 1,6-bisphosphate 1-phosphatase activity (50%) "IPR009164 (51.3%) IPR029052 (48.7%)" "Fructose-1,6-bisphosphatase class 3 (51.3%) Metallo-dependent phosphatase-like (48.7%)" LTDAAYMEANVCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) LVNNLDAFK root 1.1.1.22 (100%) UDP-glucose 6-dehydrogenase (100%) "GO:0000271 (28.4%) GO:0006065 (10.2%) GO:0006355 (1.1%)" "GO:0051287 (29.5%) GO:0003979 (28.4%) GO:0003677 (1.1%)" "polysaccharide biosynthetic process (28.4%) UDP-glucuronate biosynthetic process (10.2%) regulation of DNA-templated transcription (1.1%)" "NAD binding (29.5%) UDP-glucose 6-dehydrogenase activity (28.4%) DNA binding (1.1%)" "IPR001732 (11.2%) IPR014026 (11.2%) IPR014027 (11.2%)" "UDP-glucose/GDP-mannose dehydrogenase, N-terminal (11.2%) UDP-glucose/GDP-mannose dehydrogenase, dimerisation (11.2%) UDP-glucose/GDP-mannose dehydrogenase, C-terminal (11.2%)" NGDELLSSLYER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) GO:0000428 (16.9%) "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (16.2%)" DNA-templated transcription (16.9%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (16.2%)" "IPR007081 (9.6%) IPR007083 (9.6%) IPR000722 (9.2%)" "RNA polymerase Rpb1, domain 5 (9.6%) RNA polymerase Rpb1, domain 4 (9.6%) RNA polymerase, alpha subunit (9.2%)" GQTYFANQMYEQALKGDGAGYVGFTK Pseudomonadati Bacteria Pseudomonadati GO:0016020 (100%) membrane (100%) "IPR019734 (34.2%) IPR011990 (32.9%) IPR018704 (32.9%)" "Tetratricopeptide repeat (34.2%) Tetratricopeptide-like helical domain superfamily (32.9%) Ancillary SecYEG translocon subunit/Cell division coordinator CpoB, TPR domain (32.9%)" DFDNPWGLTTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.2.1 (100%) glycine hydroxymethyltransferase (100%) "GO:0019264 (16.3%) GO:0035999 (16.3%) GO:0032259 (9.2%)" GO:0005829 (16.3%) "GO:0004372 (16.3%) GO:0030170 (16.3%) GO:0008168 (9.2%)" "glycine biosynthetic process from serine (16.3%) tetrahydrofolate interconversion (16.3%) methylation (9.2%)" cytosol (16.3%) "glycine hydroxymethyltransferase activity (16.3%) pyridoxal phosphate binding (16.3%) methyltransferase activity (9.2%)" "IPR001085 (14.5%) IPR019798 (14.5%) IPR039429 (14.5%)" "Serine hydroxymethyltransferase (14.5%) Serine hydroxymethyltransferase, pyridoxal phosphate binding site (14.5%) Serine hydroxymethyltransferase-like domain (14.5%)" LSDYMHFALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0016746 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" acyltransferase activity (33.3%) IPR002123 (100%) Phospholipid/glycerol acyltransferase (100%) SLADAVAAGMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008146 (14.4%) IPR008147 (14.4%) IPR022147 (14.4%)" "Glutamine synthetase, catalytic domain (14.4%) Glutamine synthetase, N-terminal domain (14.4%) Glutamine synthetase type III N-terminal (14.4%)" MPSLVPVYEEDGKTFAGPVGSMADR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NPDVFELLR root 4.3.2.1 (100%) argininosuccinate lyase (100%) "GO:0042450 (33.1%) GO:0000288 (0%) GO:0009063 (0%)" "GO:0005829 (33.1%) GO:0005737 (0%)" "GO:0004056 (33.1%) GO:0004042 (0.3%) GO:0000287 (0%)" "L-arginine biosynthetic process via ornithine (33.1%) nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (0%) amino acid catabolic process (0%)" "cytosol (33.1%) cytoplasm (0%)" "argininosuccinate lyase activity (33.1%) L-glutamate N-acetyltransferase activity (0.3%) magnesium ion binding (0%)" "IPR009049 (16.6%) IPR020557 (16.6%) IPR022761 (16.6%)" "Argininosuccinate lyase (16.6%) Fumarate lyase, conserved site (16.6%) Fumarate lyase, N-terminal (16.6%)" YFAQNNLTVYYLNATK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.5%) GO:0022900 (14.5%) GO:0044281 (13.3%)" "GO:0005506 (14.5%) GO:0030976 (14.5%) GO:0051539 (14.5%)" "response to oxidative stress (14.5%) electron transport chain (14.5%) small molecule metabolic process (13.3%)" "iron ion binding (14.5%) thiamine pyrophosphate binding (14.5%) 4 iron, 4 sulfur cluster binding (14.5%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" TGEALPLLNDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LQEGLCALAGYGELFER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.-.-.- (100%) Ligases (100%) "GO:0015977 (20.9%) GO:0006633 (5.7%)" GO:0009317 (20.9%) "GO:0004658 (23.4%) GO:0003989 (20.9%) GO:0016740 (7.6%)" "carbon fixation (20.9%) fatty acid biosynthetic process (5.7%)" acetyl-CoA carboxylase complex (20.9%) "propionyl-CoA carboxylase activity (23.4%) acetyl-CoA carboxylase activity (20.9%) transferase activity (7.6%)" "IPR011762 (19.3%) IPR011763 (19.3%) IPR034733 (19.3%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (19.3%) Acetyl-coenzyme A carboxyltransferase, C-terminal (19.3%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (19.3%)" YDAAHTDLSEEDLEEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" SLLSYLPSNNTEEAPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.-.-.- (100%) Ligases (100%) "GO:0015977 (21.6%) GO:0006633 (10.2%)" GO:0009317 (21.6%) "GO:0004658 (23.9%) GO:0003989 (21.6%) GO:0016740 (1.1%)" "carbon fixation (21.6%) fatty acid biosynthetic process (10.2%)" acetyl-CoA carboxylase complex (21.6%) "propionyl-CoA carboxylase activity (23.9%) acetyl-CoA carboxylase activity (21.6%) transferase activity (1.1%)" "IPR011762 (18.8%) IPR011763 (18.8%) IPR034733 (18.8%)" "Acetyl-coenzyme A carboxyltransferase, N-terminal (18.8%) Acetyl-coenzyme A carboxyltransferase, C-terminal (18.8%) Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (18.8%)" AEVTDLANALFYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.40 (100%) pyruvate kinase (100%) GO:0006950 (0.7%) "GO:0000287 (19.9%) GO:0004743 (19.9%) GO:0005524 (19.9%)" response to stress (0.7%) "magnesium ion binding (19.9%) pyruvate kinase activity (19.9%) ATP binding (19.9%)" "IPR001697 (11.3%) IPR015793 (11.3%) IPR015795 (11.3%)" "Pyruvate kinase (11.3%) Pyruvate kinase, barrel (11.3%) Pyruvate kinase, C-terminal (11.3%)" LFYNNFVQNHNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR041700 (87%) IPR008969 (13%)" "Outer membrane protein beta-barrel domain 3 (87%) Carboxypeptidase-like, regulatory domain superfamily (13%)" LLQLSYLK root "2.7.7.7 (75%) 2.1.1.192 (12.5%) 5.6.2.3 (12.5%)" "DNA-directed DNA polymerase (75%) 23S rRNA (adenine(2503)-C(2))-methyltransferase (12.5%) DNA 5'-3' helicase (12.5%)" "GO:0045004 (20.8%) GO:0032259 (0.4%) GO:0006260 (0.2%)" "GO:0005829 (20.8%) GO:0016020 (5.4%) GO:0005737 (0.6%)" "GO:0008408 (20.8%) GO:0003676 (20.6%) GO:0003887 (1.3%)" "DNA replication proofreading (20.8%) methylation (0.4%) DNA replication (0.2%)" "cytosol (20.8%) membrane (5.4%) cytoplasm (0.6%)" "3'-5' exonuclease activity (20.8%) nucleic acid binding (20.6%) DNA-directed DNA polymerase activity (1.3%)" "IPR012337 (19.6%) IPR013520 (19.6%) IPR036397 (19.4%)" "Ribonuclease H-like superfamily (19.6%) Ribonuclease H-like domain (19.6%) Ribonuclease H superfamily (19.4%)" GLTYNQFGDKEQFLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) TELYQHFTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034707 (46%) GO:0016020 (4%)" "GO:0005254 (46%) GO:0015108 (4%)" "chloride channel complex (46%) membrane (4%)" "chloride channel activity (46%) chloride transmembrane transporter activity (4%)" "IPR000644 (21.1%) IPR001807 (20.3%) IPR050368 (20.3%)" "CBS domain (21.1%) Chloride channel (20.3%) Voltage-gated ClC-type chloride channel (20.3%)" RGDLEVLFDNTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR024370 (50%) IPR050811 (50%)" "PBP domain (50%) Phosphate-binding ABC transporter substrate-binding (50%)" GQVEDQLLPYGVDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0033539 (33.3%) "GO:0009055 (33.3%) GO:0050660 (33.3%)" fatty acid beta-oxidation using acyl-CoA dehydrogenase (33.3%) "electron transfer activity (33.3%) flavin adenine dinucleotide binding (33.3%)" "IPR001308 (17.1%) IPR014729 (17.1%) IPR014730 (17.1%)" "Electron transfer flavoprotein alpha subunit/FixB (17.1%) Rossmann-like alpha/beta/alpha sandwich fold (17.1%) Electron transfer flavoprotein, alpha/beta-subunit, N-terminal (17.1%)" VPVLLLFNK root 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0042274 (7%) GO:0042254 (0.5%)" "GO:0005737 (7.5%) GO:0016020 (0.9%)" "GO:0003924 (34.3%) GO:0005525 (34.3%) GO:0019843 (7.5%)" "ribosomal small subunit biogenesis (7%) ribosome biogenesis (0.5%)" "cytoplasm (7.5%) membrane (0.9%)" "GTPase activity (34.3%) GTP binding (34.3%) rRNA binding (7.5%)" "IPR027417 (34.7%) IPR006689 (27.2%) IPR004881 (7.5%)" "P-loop containing nucleoside triphosphate hydrolase (34.7%) Small GTPase superfamily, ARF/SAR type (27.2%) Ribosome biogenesis GTPase RsgA (7.5%)" RLVPYSPGCGSVTELNNAQAAGCDVTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "4.1.2.14 (50%) 4.1.3.16 (50%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (50%) 4-hydroxy-2-oxoglutarate aldolase (50%)" "GO:0016829 (64.7%) GO:0008675 (17.6%) GO:0008700 (17.6%)" "lyase activity (64.7%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (17.6%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (17.6%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" EMTEADQGFNAVYMMLDSGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) GO:0000428 (16.9%) "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (16.3%)" DNA-templated transcription (16.9%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (16.3%)" "IPR007081 (9.4%) IPR007083 (9.4%) IPR000722 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.4%) RNA polymerase Rpb1, domain 4 (9.4%) RNA polymerase, alpha subunit (9.1%)" VLLKPAAAGTGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (16.7%) GO:0042254 (16.2%)" "GO:0005737 (16.7%) GO:0015935 (16.2%) GO:0005840 (0.5%)" "GO:0003735 (16.7%) GO:0019843 (16.2%) GO:0003723 (0.5%)" "translation (16.7%) ribosome biogenesis (16.2%)" "cytoplasm (16.7%) small ribosomal subunit (16.2%) ribosome (0.5%)" "structural constituent of ribosome (16.7%) rRNA binding (16.2%) RNA binding (0.5%)" "IPR000851 (14.4%) IPR005324 (14.4%) IPR013810 (14.4%)" "Small ribosomal subunit protein uS5 (14.4%) Small ribosomal subunit protein uS5, C-terminal (14.4%) Small ribosomal subunit protein uS5, N-terminal (14.4%)" NVDVLLNNAGLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016616 (100%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (100%) "IPR002347 (33.3%) IPR020904 (33.3%) IPR036291 (33.3%)" "Short-chain dehydrogenase/reductase SDR (33.3%) Short-chain dehydrogenase/reductase, conserved site (33.3%) NAD(P)-binding domain superfamily (33.3%)" SVTDVATDDAVSNDLSNSYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" EYDHELNDEELREQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (8.1%) IPR012162 (8.1%) IPR015847 (8.1%)" "Exoribonuclease, phosphorolytic domain 1 (8.1%) Polyribonucleotide nucleotidyltransferase (8.1%) Exoribonuclease, phosphorolytic domain 2 (8.1%)" LGLHGSPTCELVYK Pseudomonadati Bacteria Pseudomonadati "1.3.8.1 (61.3%) 1.3.99.- (22.6%) 1.3.8.- (12.9%)" "short-chain acyl-CoA dehydrogenase (61.3%) With other acceptors (22.6%) With a flavin as acceptor (12.9%)" "GO:0050660 (49.8%) GO:0003995 (29.6%) GO:0016627 (17.5%)" "flavin adenine dinucleotide binding (49.8%) acyl-CoA dehydrogenase activity (29.6%) oxidoreductase activity, acting on the CH-CH group of donors (17.5%)" "IPR009075 (9.5%) IPR052166 (9.5%) IPR006091 (9.4%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (9.5%) Diverse substrate specificity acyl-CoA dehydrogenase (9.5%) Acyl-CoA oxidase/dehydrogenase, middle domain (9.4%)" GFLNDLDDLLGSPAHESNDNHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" YFMQVNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023996 (14.5%) IPR036942 (14.5%) IPR008969 (13.8%)" "TonB-dependent outer membrane protein, SusC/RagA (14.5%) TonB-dependent receptor-like, beta-barrel domain superfamily (14.5%) Carboxypeptidase-like, regulatory domain superfamily (13.8%)" ALFNSPDNEAFYGLGQHQSEELNMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" GDLCDFDLMLK Pseudomonadati Bacteria Pseudomonadati 4.2.1.46 (100%) dTDP-glucose 4,6-dehydratase (100%) GO:0009225 (50%) GO:0008460 (50%) nucleotide-sugar metabolic process (50%) dTDP-glucose 4,6-dehydratase activity (50%) "IPR036291 (34.1%) IPR005888 (31.2%) IPR001509 (28.3%)" "NAD(P)-binding domain superfamily (34.1%) dTDP-glucose 4,6-dehydratase (31.2%) NAD-dependent epimerase/dehydratase (28.3%)" LPVTTLLR root "2.7.7.6 (99.1%) 1.1.1.338 (0.2%) 2.7.11.1 (0.2%)" "DNA-directed RNA polymerase (99.1%) (2R)-3-sulfolactate dehydrogenase (NADP(+)) (0.2%) non-specific serine/threonine protein kinase (0.2%)" "GO:0006351 (19.2%) GO:0006508 (0.4%) GO:0000724 (0.1%)" "GO:0000428 (19.1%) GO:0016020 (0.4%) GO:0005886 (0.3%)" "GO:0003677 (19.3%) GO:0003899 (19.2%) GO:0032549 (19%)" "DNA-templated transcription (19.2%) proteolysis (0.4%) double-strand break repair via homologous recombination (0.1%)" "DNA-directed RNA polymerase complex (19.1%) membrane (0.4%) plasma membrane (0.3%)" "DNA binding (19.3%) DNA-directed RNA polymerase activity (19.2%) ribonucleoside binding (19%)" "IPR007642 (7.8%) IPR015712 (7.8%) IPR007645 (7.7%)" "RNA polymerase Rpb2, domain 2 (7.8%) DNA-directed RNA polymerase, subunit 2 (7.8%) RNA polymerase Rpb2, domain 3 (7.7%)" DANLPALYLLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" DWLDDAK root "2.8.4.4 (50%) 3.1.11.2 (16.7%) 3.4.16.- (16.7%)" "[ribosomal protein uS12] (aspartate(89)-C(3))-methylthiotransferase (50%) exodeoxyribonuclease III (16.7%) Serine-type carboxypeptidases (16.7%)" "GO:0000972 (1.6%) GO:0006281 (1.6%) GO:0006396 (1.6%)" "GO:0009279 (19.2%) GO:0016020 (3.2%) GO:0005634 (2.4%)" "GO:0003677 (3.2%) GO:0008270 (2.4%) GO:0046872 (2.4%)" "transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery (1.6%) DNA repair (1.6%) RNA processing (1.6%)" "cell outer membrane (19.2%) membrane (3.2%) nucleus (2.4%)" "DNA binding (3.2%) zinc ion binding (2.4%) metal ion binding (2.4%)" "IPR000531 (6.7%) IPR008969 (6.7%) IPR012910 (6.7%)" "TonB-dependent receptor-like, beta-barrel (6.7%) Carboxypeptidase-like, regulatory domain superfamily (6.7%) TonB-dependent receptor, plug domain (6.7%)" QALLAGYLK Pseudomonadati Bacteria Pseudomonadati "5.6.2.4 (86.2%) 3.6.4.12 (10.8%) 3.4.21.- (1.5%)" "DNA 3'-5' helicase (86.2%) DNA helicase (10.8%) Serine endopeptidases (1.5%)" "GO:0006260 (8.5%) GO:0006281 (8.5%) GO:0006310 (8.3%)" "GO:0005737 (8.3%) GO:0030894 (8.3%) GO:0043590 (8.3%)" "GO:0043138 (8.5%) GO:0009378 (8.3%) GO:0016787 (8.3%)" "DNA replication (8.5%) DNA repair (8.5%) DNA recombination (8.3%)" "cytoplasm (8.3%) replisome (8.3%) bacterial nucleoid (8.3%)" "3'-5' DNA helicase activity (8.5%) four-way junction helicase activity (8.3%) hydrolase activity (8.3%)" "IPR018982 (7.4%) IPR001650 (7.3%) IPR002121 (7.3%)" "RQC domain (7.4%) Helicase, C-terminal domain-like (7.3%) HRDC domain (7.3%)" YCPTPYVNDAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri YGYNGQPQAQFVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (37.5%) GO:0009279 (62.5%) iron ion transport (37.5%) cell outer membrane (62.5%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LSMTTASLAR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0043571 (1.3%) GO:0051607 (1.3%)" "GO:0009279 (45.6%) GO:1990351 (45.6%)" "GO:0003677 (1.3%) GO:0004520 (1.3%) GO:0016301 (1.3%)" "maintenance of CRISPR repeat elements (1.3%) defense response to virus (1.3%)" "cell outer membrane (45.6%) transporter complex (45.6%)" "DNA binding (1.3%) DNA endonuclease activity (1.3%) kinase activity (1.3%)" "IPR045659 (47.4%) IPR050218 (47.4%) IPR002729 (1.3%)" "LPS-assembly protein LptD, central domain (47.4%) Lipopolysaccharide Assembly Protein LptD (47.4%) CRISPR-associated protein Cas1 (1.3%)" TEHMFFDDQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (97.5%) 2.7.-.- (2.5%)" "pyruvate, phosphate dikinase (97.5%) Transferring phosphorus-containing groups (2.5%)" "GO:0050242 (25.5%) GO:0005524 (24.8%) GO:0016301 (24.8%)" "pyruvate, phosphate dikinase activity (25.5%) ATP binding (24.8%) kinase activity (24.8%)" "IPR000121 (10.2%) IPR010121 (10.2%) IPR015813 (10.2%)" "PEP-utilising enzyme, C-terminal (10.2%) Pyruvate, phosphate dikinase (10.2%) Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.2%)" DGLVLDEPANFHTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.5.1.4 (100%) inositol-3-phosphate synthase (100%) "GO:0006021 (27.8%) GO:0008654 (27.8%)" GO:0016020 (16.6%) GO:0004512 (27.8%) "inositol biosynthetic process (27.8%) phospholipid biosynthetic process (27.8%)" membrane (16.6%) inositol-3-phosphate synthase activity (27.8%) "IPR002587 (33.5%) IPR013021 (33.5%) IPR036291 (33.1%)" "Myo-inositol-1-phosphate synthase (33.5%) Myo-inositol-1-phosphate synthase, GAPDH-like (33.5%) NAD(P)-binding domain superfamily (33.1%)" FLLHYNFPPFSTGEAK Pseudomonadati Bacteria Pseudomonadati 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.2%) GO:0006401 (0.1%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0003723 (14.3%) GO:0004654 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.2%) RNA catabolic process (0.1%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%) polyribonucleotide nucleotidyltransferase activity (14.3%)" "IPR001247 (8%) IPR012162 (8%) IPR015847 (8%)" "Exoribonuclease, phosphorolytic domain 1 (8%) Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 2 (8%)" YGAVMLDNSSAFR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (11%) GO:0009089 (11%) GO:0009097 (11%)" "GO:0051287 (11.2%) GO:0046983 (11.1%) GO:0004073 (11%)" "threonine biosynthetic process (11%) lysine biosynthetic process via diaminopimelate (11%) isoleucine biosynthetic process (11%)" "NAD binding (11.2%) protein dimerization activity (11.1%) aspartate-semialdehyde dehydrogenase activity (11%)" "IPR000534 (19.3%) IPR036291 (19.3%) IPR012280 (19.1%)" "Semialdehyde dehydrogenase, NAD-binding (19.3%) NAD(P)-binding domain superfamily (19.3%) Semialdehyde dehydrogenase, dimerisation domain (19.1%)" DATGEPLLGATLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (17.6%) GO:0009279 (82.4%) iron ion transport (17.6%) cell outer membrane (82.4%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" VKADAVQTSTDFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" WGSLGYPSFDGTNYTLQDGLYKDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DQVNLNANYVEESAVDAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (24.7%) GO:0006080 (23.6%) GO:0030245 (6.7%)" "GO:0005576 (6.7%) GO:0009986 (6.7%)" "GO:0016985 (23.6%) GO:0008422 (6.7%) GO:0004553 (1.1%)" "polysaccharide catabolic process (24.7%) substituted mannan metabolic process (23.6%) cellulose catabolic process (6.7%)" "extracellular region (6.7%) cell surface (6.7%)" "mannan endo-1,4-beta-mannosidase activity (23.6%) beta-glucosidase activity (6.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.1%)" "IPR001547 (25.5%) IPR022790 (25.5%) IPR017853 (24.5%)" "Glycoside hydrolase, family 5 (25.5%) Glycosyl hydrolase family 26 domain (25.5%) Glycoside hydrolase superfamily (24.5%)" NTADFGVTHFAMNTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (25%) "GO:0003861 (25%) GO:0046872 (25%) GO:0051539 (25%)" L-leucine biosynthetic process (25%) "3-isopropylmalate dehydratase activity (25%) metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%)" "IPR001030 (14.9%) IPR050067 (14.9%) IPR015931 (14.4%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.9%) Isopropylmalate dehydratase and related enzymes (14.9%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (14.4%)" AGATVVNLPDTTGYCLPDEYGDKLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" FVLGGPHGDTGLTGR root 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.8%) GO:0006730 (16.7%)" "GO:0005737 (16.1%) GO:0005829 (0%) GO:0016020 (0%)" "GO:0004478 (16.8%) GO:0005524 (16.8%) GO:0000287 (16%)" "S-adenosylmethionine biosynthetic process (16.8%) one-carbon metabolic process (16.7%)" "cytoplasm (16.1%) cytosol (0%) membrane (0%)" "methionine adenosyltransferase activity (16.8%) ATP binding (16.8%) magnesium ion binding (16%)" "IPR002133 (16.7%) IPR022630 (16.7%) IPR022631 (16.7%)" "S-adenosylmethionine synthetase (16.7%) S-adenosylmethionine synthetase, C-terminal (16.7%) S-adenosylmethionine synthetase, conserved site (16.7%)" NLFDLDYVGLK Pseudomonadati Bacteria Pseudomonadati "6.3.5.5 (94.8%) 6.3.4.16 (5.2%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (94.8%) carbamoyl-phosphate synthase (ammonia) (5.2%)" "GO:0006541 (13.9%) GO:0006221 (11.5%) GO:0006526 (11.5%)" GO:0005737 (13.9%) "GO:0004088 (13.9%) GO:0005524 (13.9%) GO:0046872 (13.6%)" "glutamine metabolic process (13.9%) pyrimidine nucleotide biosynthetic process (11.5%) L-arginine biosynthetic process (11.5%)" cytoplasm (13.9%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.9%) ATP binding (13.9%) metal ion binding (13.6%)" "IPR011607 (10.3%) IPR036914 (10.3%) IPR005479 (10.2%)" "Methylglyoxal synthase-like domain (10.3%) Methylglyoxal synthase-like domain superfamily (10.3%) Carbamoyl phosphate synthase, ATP-binding domain (10.2%)" SNLLMVGSTGTGK Pseudomonadati Bacteria Pseudomonadati "GO:0051301 (10.1%) GO:0051603 (10.1%) GO:0006260 (0%)" GO:0009376 (10.1%) "GO:0005524 (10.2%) GO:0016887 (10.1%) GO:0051082 (10%)" "cell division (10.1%) proteolysis involved in protein catabolic process (10.1%) DNA replication (0%)" HslUV protease complex (10.1%) "ATP binding (10.2%) ATP hydrolysis activity (10.1%) unfolded protein binding (10%)" "IPR003593 (11.4%) IPR003959 (11.3%) IPR050052 (11.3%)" "AAA+ ATPase domain (11.4%) ATPase, AAA-type, core (11.3%) ATP-dependent Clp protease ATP-binding subunit ClpX (11.3%)" YGNYGSYGSYGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25%) "GO:0005524 (25%) GO:0042802 (25%) GO:0004713 (17.4%)" plasma membrane (25%) "ATP binding (25%) identical protein binding (25%) protein tyrosine kinase activity (17.4%)" "IPR003856 (16.8%) IPR005702 (16.8%) IPR025669 (16.8%)" "Polysaccharide chain length determinant, N-terminal domain (16.8%) Tyrosine-protein kinase Wzc-like, C-terminal domain (16.8%) AAA domain (16.8%)" LLMTGNPVR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (11.7%) GO:0030259 (11.7%) GO:0008360 (11.7%)" GO:0005886 (11.7%) "GO:0050511 (11.7%) GO:0051991 (6.2%) GO:0016757 (0.1%)" "carbohydrate metabolic process (11.7%) obsolete lipid glycosylation (11.7%) regulation of cell shape (11.7%)" plasma membrane (11.7%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (11.7%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (6.2%) glycosyltransferase activity (0.1%)" "IPR004276 (33.5%) IPR006009 (33.2%) IPR007235 (33.2%)" "Glycosyltransferase family 28, N-terminal domain (33.5%) N-acetylglucosaminyltransferase, MurG (33.2%) Glycosyl transferase, family 28, C-terminal (33.2%)" AGTSDYADNYDEAGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.9%) GO:0006811 (3.1%)" GO:0009279 (50%) "iron ion transport (46.9%) monoatomic ion transport (3.1%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" LVYAGVGK root "4.1.1.20 (99.2%) 3.6.3.28 (0.4%) 5.1.1.7 (0.4%)" "diaminopimelate decarboxylase (99.2%) Transferred entry: 7.3.2.2 (0.4%) diaminopimelate epimerase (0.4%)" "GO:0009089 (33%) GO:0006596 (0.1%)" "GO:0005886 (1.3%) GO:0005737 (0.1%)" "GO:0008836 (33%) GO:0030170 (26.2%) GO:0005524 (2.3%)" "lysine biosynthetic process via diaminopimelate (33%) polyamine biosynthetic process (0.1%)" "plasma membrane (1.3%) cytoplasm (0.1%)" "diaminopimelate decarboxylase activity (33%) pyridoxal phosphate binding (26.2%) ATP binding (2.3%)" "IPR022644 (13.5%) IPR029066 (13.3%) IPR002986 (13.3%)" "Orn/DAP/Arg decarboxylase 2, N-terminal (13.5%) PLP-binding barrel (13.3%) Diaminopimelate decarboxylase, LysA (13.3%)" SYYAALFR root "GO:0045893 (8.3%) GO:0000105 (4.2%) GO:0000162 (4.2%)" "GO:0009279 (41.7%) GO:0005634 (8.3%) GO:0005737 (4.2%)" "GO:0000976 (8.3%) GO:0003700 (8.3%) GO:0046982 (8.3%)" "positive regulation of DNA-templated transcription (8.3%) L-histidine biosynthetic process (4.2%) L-tryptophan biosynthetic process (4.2%)" "cell outer membrane (41.7%) nucleus (8.3%) cytoplasm (4.2%)" "transcription cis-regulatory region binding (8.3%) DNA-binding transcription factor activity (8.3%) protein heterodimerization activity (8.3%)" "IPR012944 (25%) IPR033985 (25%) IPR011990 (22.5%)" "RagB/SusD domain (25%) SusD-like, N-terminal (25%) Tetratricopeptide-like helical domain superfamily (22.5%)" ASMELLNNYYLTSNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR041662 (40.4%) IPR011990 (36.8%) IPR024302 (22.8%)" "SusD-like 2 (40.4%) Tetratricopeptide-like helical domain superfamily (36.8%) SusD-like (22.8%)" TDLGCALEYFTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002035 (34.2%) IPR002881 (34.2%) IPR036465 (31.6%)" "von Willebrand factor, type A (34.2%) Domain of unknown function DUF58 (34.2%) von Willebrand factor A-like domain superfamily (31.6%)" FGGTSVGSVK Bacteria Bacteria "2.7.2.4 (54.2%) 1.1.1.3 (45.8%)" "aspartate kinase (54.2%) homoserine dehydrogenase (45.8%)" "GO:0009089 (11.8%) GO:0009090 (11.8%) GO:0009088 (11.1%)" GO:0005829 (1.7%) "GO:0004072 (11.8%) GO:0005524 (11.7%) GO:0004412 (10%)" "lysine biosynthetic process via diaminopimelate (11.8%) homoserine biosynthetic process (11.8%) threonine biosynthetic process (11.1%)" cytosol (1.7%) "aspartate kinase activity (11.8%) ATP binding (11.7%) homoserine dehydrogenase activity (10%)" "IPR001048 (7.6%) IPR018042 (7.6%) IPR001341 (7.5%)" "Aspartate/glutamate/uridylate kinase (7.6%) Aspartate kinase, conserved site (7.6%) Aspartate kinase (7.5%)" ELNLSGPFNLQYLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (72.8%) 6.3.4.16 (27.2%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (72.8%) carbamoyl-phosphate synthase (ammonia) (27.2%)" "GO:0006541 (14%) GO:0006221 (11.7%) GO:0006526 (11.7%)" GO:0005737 (14%) "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (14%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (11.7%) L-arginine biosynthetic process (11.7%)" cytoplasm (14%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (14%)" "IPR005479 (10.2%) IPR005480 (10.2%) IPR011607 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.2%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.2%) Methylglyoxal synthase-like domain (10.2%)" LLREETQCFAFLAGHESFAAAEGALK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR025964 (100%) GGGtGRT protein (100%) GLSEQQLEHQLEQLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025393 (51.5%) IPR029044 (48.5%)" "Domain of unknown function DUF4301 (51.5%) Nucleotide-diphospho-sugar transferases (48.5%)" LLELLER root "2.3.2.27 (19%) 6.1.1.2 (9%) 3.6.4.- (7%)" "RING-type E3 ubiquitin transferase (19%) tryptophan--tRNA ligase (9%) Acting on ATP; involved in cellular and subcellular movement (7%)" "GO:0051301 (1.4%) GO:0007076 (1.2%) GO:0006355 (1.2%)" "GO:0005829 (3.4%) GO:0005737 (3.2%) GO:0016020 (1.8%)" "GO:0005524 (5.2%) GO:0008270 (2.9%) GO:0005525 (2.4%)" "cell division (1.4%) mitotic chromosome condensation (1.2%) regulation of DNA-templated transcription (1.2%)" "cytosol (3.4%) cytoplasm (3.2%) membrane (1.8%)" "ATP binding (5.2%) zinc ion binding (2.9%) GTP binding (2.4%)" "IPR027417 (3.9%) IPR013083 (1.5%) IPR001841 (1.5%)" "P-loop containing nucleoside triphosphate hydrolase (3.9%) Zinc finger, RING/FYVE/PHD-type (1.5%) Zinc finger, RING-type (1.5%)" VLLNVVVR root "3.1.3.16 (60%) 5.2.1.8 (20%) 6.2.1.3 (20%)" "protein-serine/threonine phosphatase (60%) peptidylprolyl isomerase (20%) long-chain-fatty-acid--CoA ligase (20%)" "GO:0006808 (18.9%) GO:0030488 (1.9%) GO:0051056 (1.9%)" "GO:0005829 (20.8%) GO:0016020 (7.5%) GO:0005783 (1.9%)" "GO:0005524 (20.8%) GO:0030234 (18.9%) GO:0004467 (1.9%)" "regulation of nitrogen utilization (18.9%) tRNA methylation (1.9%) regulation of small GTPase mediated signal transduction (1.9%)" "cytosol (20.8%) membrane (7.5%) endoplasmic reticulum (1.9%)" "ATP binding (20.8%) enzyme regulator activity (18.9%) long-chain fatty acid-CoA ligase activity (1.9%)" "IPR002187 (14.5%) IPR011322 (14.5%) IPR015867 (14.5%)" "Nitrogen regulatory protein PII (14.5%) Nitrogen regulatory PII-like, alpha/beta (14.5%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (14.5%)" VTVGVFDCMTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.1%) IPR002469 (25.1%) IPR050278 (25.1%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.1%) Dipeptidylpeptidase IV, N-terminal domain (25.1%) Serine protease S9B/DPPIV (25.1%)" NTYVLPLLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" VDAAPVTVLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (50%) GO:0008236 (50%) proteolysis (50%) serine-type peptidase activity (50%) "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" YFVTNYHSDWAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" LVTGANLNVKGDDLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (28.2%) GO:0009279 (43.6%) GO:0015344 (28.2%) siderophore transmembrane transport (28.2%) cell outer membrane (43.6%) siderophore uptake transmembrane transporter activity (28.2%) "IPR012910 (13.7%) IPR023996 (13.7%) IPR023997 (13.7%)" "TonB-dependent receptor, plug domain (13.7%) TonB-dependent outer membrane protein, SusC/RagA (13.7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.7%)" VLLVGDPGR root "2.4.2.3 (99.3%) 4.2.1.136 (0.3%) 5.1.99.6 (0.3%)" "uridine phosphorylase (99.3%) ADP-dependent NAD(P)H-hydrate dehydratase (0.3%) NAD(P)H-hydrate epimerase (0.3%)" "GO:0006152 (31.3%) GO:0009164 (0.6%) GO:0009116 (0.3%)" "GO:0005829 (32.2%) GO:0005759 (0.2%) GO:0016020 (0.1%)" "GO:0004731 (31.3%) GO:0004850 (2%) GO:0016763 (0.6%)" "purine nucleoside catabolic process (31.3%) nucleoside catabolic process (0.6%) nucleoside metabolic process (0.3%)" "cytosol (32.2%) mitochondrial matrix (0.2%) membrane (0.1%)" "purine-nucleoside phosphorylase activity (31.3%) uridine phosphorylase activity (2%) pentosyltransferase activity (0.6%)" "IPR000845 (48.7%) IPR035994 (48.4%) IPR018016 (0.9%)" "Nucleoside phosphorylase domain (48.7%) Nucleoside phosphorylase superfamily (48.4%) Nucleoside phosphorylase, conserved site (0.9%)" LPLNQVGALSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006352 (32.9%) "GO:0003677 (32.9%) GO:0016987 (32.9%) GO:0003899 (1.3%)" DNA-templated transcription initiation (32.9%) "DNA binding (32.9%) sigma factor activity (32.9%) DNA-directed RNA polymerase activity (1.3%)" "IPR000943 (10%) IPR007624 (10%) IPR007627 (10%)" "RNA polymerase sigma-70 (10%) RNA polymerase sigma-70 region 3 (10%) RNA polymerase sigma-70 region 2 (10%)" ALDTPMGSLTGGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.9%) GO:0005737 (24.9%) "GO:0004821 (25.4%) GO:0005524 (24.9%)" histidyl-tRNA aminoacylation (24.9%) cytoplasm (24.9%) "histidine-tRNA ligase activity (25.4%) ATP binding (24.9%)" "IPR004154 (12.7%) IPR033656 (12.7%) IPR041715 (12.7%)" "Anticodon-binding (12.7%) Histidyl-anticodon-binding (12.7%) Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.7%)" FYASWNK root "2.3.2.26 (50%) 5.6.2.3 (50%)" "HECT-type E3 ubiquitin transferase (50%) DNA 5'-3' helicase (50%)" "GO:0044718 (18.5%) GO:0000122 (3%) GO:0015891 (3%)" "GO:0009279 (21.5%) GO:0005654 (3%) GO:0005730 (3%)" "GO:0015344 (21.5%) GO:0003714 (3%) GO:0038023 (3%)" "siderophore transmembrane transport (18.5%) negative regulation of transcription by RNA polymerase II (3%) siderophore transport (3%)" "cell outer membrane (21.5%) nucleoplasm (3%) nucleolus (3%)" "siderophore uptake transmembrane transporter activity (21.5%) transcription corepressor activity (3%) signaling receptor activity (3%)" "IPR000531 (17.7%) IPR039426 (17.7%) IPR012910 (17.3%)" "TonB-dependent receptor-like, beta-barrel (17.7%) TonB-dependent receptor-like (17.7%) TonB-dependent receptor, plug domain (17.3%)" FYLPNNLQMGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SDKNSFLVFSGTNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (11.1%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (11.1%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (16.7%) IPR000842 (16.7%) IPR005946 (16.7%)" "Phosphoribosyltransferase domain (16.7%) Phosphoribosyl pyrophosphate synthetase, conserved site (16.7%) Ribose-phosphate pyrophosphokinase (16.7%)" VEKFEELLNER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.6.1.1 (73.1%) 2.6.1.- (26.9%)" "aspartate transaminase (73.1%) Transaminases (26.9%)" GO:0006520 (33.2%) "GO:0030170 (33.2%) GO:0008483 (28%) GO:0004069 (5.5%)" amino acid metabolic process (33.2%) "pyridoxal phosphate binding (33.2%) transaminase activity (28%) L-aspartate:2-oxoglutarate aminotransferase activity (5.5%)" "IPR004839 (20.1%) IPR050596 (20.1%) IPR015421 (20%)" "Aminotransferase, class I/classII, large domain (20.1%) Aspartate/prephenate aminotransferase-like (20.1%) Pyridoxal phosphate-dependent transferase, major domain (20%)" LTTDENGEAYFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR002890 (19.6%) IPR051802 (19.6%) IPR001599 (19.1%)" "Macroglobulin domain (19.6%) Alpha-2-macroglobulin-like (19.6%) Alpha-2-macroglobulin (19.1%)" GDYLLDYENAHLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030247 (100%) polysaccharide binding (100%) "IPR013783 (28.9%) IPR014756 (28.9%) IPR040475 (28.9%)" "Immunoglobulin-like fold (28.9%) Immunoglobulin E-set (28.9%) Surface glycan-binding protein B, xyloglucan binding domain (28.9%)" GKLDNQSLPSNFSTGVGLQLLNNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (48.8%) GO:0015562 (51.2%) plasma membrane (48.8%) efflux transmembrane transporter activity (51.2%) "IPR003423 (33.9%) IPR050737 (33.9%) IPR010131 (32.3%)" "Outer membrane efflux protein (33.9%) Unknown (33.9%) Multidrug resistance outer membrane protein MdtP/Nodulation protein T-like (32.3%)" GMLHFDLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" NLEYDGVQSNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007121 (7.9%) IPR007641 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase, beta subunit, conserved site (7.9%) RNA polymerase Rpb2, domain 7 (7.9%)" VGELQFPDALLKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.4%) GO:0043335 (15.8%) GO:0051083 (15.8%)" GO:0005737 (3.6%) "GO:0003755 (15.8%) GO:0043022 (15.8%) GO:0044183 (15.8%)" "protein transport (16.4%) protein unfolding (15.8%) 'de novo' cotranslational protein folding (15.8%)" cytoplasm (3.6%) "peptidyl-prolyl cis-trans isomerase activity (15.8%) ribosome binding (15.8%) protein folding chaperone (15.8%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR037041 (19.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor, C-terminal domain superfamily (19.4%)" NSQYLSLAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.- (100%) Dipeptidases (100%) GO:0006508 (50%) GO:0070573 (50%) proteolysis (50%) metallodipeptidase activity (50%) "IPR008257 (25.5%) IPR011697 (25.5%) IPR029062 (24.5%)" "Peptidase M19 (25.5%) Peptidase C26 (25.5%) Class I glutamine amidotransferase-like (24.5%)" FTAQAFYK Bacteria Bacteria "2.4.-.- (75%) 5.1.1.1 (25%)" "Glycosyltransferases (75%) alanine racemase (25%)" GO:0030632 (1.5%) "GO:0005886 (47%) GO:0005829 (1.5%)" "GO:0016757 (47%) GO:0008784 (1.5%) GO:0030170 (1.5%)" D-alanine biosynthetic process (1.5%) "plasma membrane (47%) cytosol (1.5%)" "glycosyltransferase activity (47%) alanine racemase activity (1.5%) pyridoxal phosphate binding (1.5%)" "IPR001173 (33%) IPR050256 (33%) IPR029044 (31.9%)" "Glycosyltransferase 2-like (33%) Glycosyltransferase 2 (33%) Nucleotide-diphospho-sugar transferases (31.9%)" RLELAFEDHR Pseudomonadati Bacteria Pseudomonadati GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.5%) IPR033985 (33.5%) IPR011990 (33.1%)" "RagB/SusD domain (33.5%) SusD-like, N-terminal (33.5%) Tetratricopeptide-like helical domain superfamily (33.1%)" QLDDYYDKFYNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" NVDFALPFEANGYSMTGMAGSNNYDFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) TNFDQLLQAGCHFGHLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" LNSLEDAVKDFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.5.4.25 (50%) 4.1.99.12 (50%)" "GTP cyclohydrolase II (50%) 3,4-dihydroxy-2-butanone-4-phosphate synthase (50%)" GO:0009231 (12.5%) GO:0005829 (12.5%) "GO:0000287 (12.5%) GO:0003935 (12.5%) GO:0005525 (12.5%)" riboflavin biosynthetic process (12.5%) cytosol (12.5%) "magnesium ion binding (12.5%) GTP cyclohydrolase II activity (12.5%) GTP binding (12.5%)" "IPR000422 (16.7%) IPR000926 (16.7%) IPR016299 (16.7%)" "3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB (16.7%) GTP cyclohydrolase II, RibA (16.7%) Riboflavin biosynthesis protein RibBA (16.7%)" YLTLLNLNMLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" HMEDAFNLMNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (53.6%) GO:0016787 (46.4%)" "carbohydrate binding (53.6%) hydrolase activity (46.4%)" "IPR013785 (14.3%) IPR014718 (14.3%) IPR017853 (14.3%)" "Aldolase-type TIM barrel (14.3%) Glycoside hydrolase-type carbohydrate-binding (14.3%) Glycoside hydrolase superfamily (14.3%)" LQSNDLVLFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" DMKGDNADETTGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.1%) GO:0005737 (16.2%) "GO:0005524 (17.1%) GO:0140662 (17.1%) GO:0016853 (16.2%)" protein refolding (17.1%) cytoplasm (16.2%) "ATP binding (17.1%) ATP-dependent protein folding chaperone (17.1%) isomerase activity (16.2%)" "IPR001844 (17.5%) IPR002423 (17.5%) IPR018370 (17.5%)" "Chaperonin Cpn60/GroEL (17.5%) Chaperonin Cpn60/GroEL/TCP-1 family (17.5%) Chaperonin Cpn60, conserved site (17.5%)" QDAGAYAVGVVYGTNPDPTTAGSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri ADGTLLDNVLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.7%) GO:0009090 (17.7%) GO:0009088 (11.5%)" GO:0005829 (17.7%) "GO:0004072 (17.7%) GO:0005524 (17.7%)" "lysine biosynthetic process via diaminopimelate (17.7%) homoserine biosynthetic process (17.7%) threonine biosynthetic process (11.5%)" cytosol (17.7%) "aspartate kinase activity (17.7%) ATP binding (17.7%)" "IPR001048 (14.4%) IPR001341 (14.4%) IPR005260 (14.4%)" "Aspartate/glutamate/uridylate kinase (14.4%) Aspartate kinase (14.4%) Aspartate kinase, monofunctional class (14.4%)" ECLYQYLELWK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (31.4%) GO:0005829 (31.4%) "GO:0008926 (31.4%) GO:0009026 (5.8%)" mannitol catabolic process (31.4%) cytosol (31.4%) "mannitol-1-phosphate 5-dehydrogenase activity (31.4%) tagaturonate reductase activity (5.8%)" "IPR013131 (21.2%) IPR013118 (20.7%) IPR036291 (19.7%)" "Mannitol dehydrogenase, N-terminal (21.2%) Mannitol dehydrogenase, C-terminal (20.7%) NAD(P)-binding domain superfamily (19.7%)" VENHLMTPEALWAMGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.5%) IPR001375 (20.9%) IPR011042 (20.9%)" "WD40-like beta-propeller (21.5%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20.9%) Six-bladed beta-propeller, TolB-like (20.9%)" MGHMLEELALQR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.17.1.8 (100%) 4-hydroxy-tetrahydrodipicolinate reductase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008839 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate reductase (25%) "IPR000846 (25.4%) IPR022663 (25.4%) IPR023940 (25.4%)" "Dihydrodipicolinate reductase, N-terminal (25.4%) Dihydrodipicolinate reductase, C-terminal (25.4%) Dihydrodipicolinate reductase (25.4%)" LLVDGKEFMTGDTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0004180 (50%) GO:0030246 (50%)" "carboxypeptidase activity (50%) carbohydrate binding (50%)" "IPR041700 (77.5%) IPR008969 (21.3%) IPR013784 (1.3%)" "Outer membrane protein beta-barrel domain 3 (77.5%) Carboxypeptidase-like, regulatory domain superfamily (21.3%) Carbohydrate-binding-like fold (1.3%)" TQLQFNGNTSTLGSSPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.8%) IPR023614 (48.2%)" "Phosphate-selective porin O/P (51.8%) Porin domain superfamily (48.2%)" DLFTVAGK root 6.3.1.2 (100%) glutamine synthetase (100%) "GO:0006542 (30%) GO:0008360 (6.3%) GO:0051301 (6.3%)" "GO:0005886 (7.5%) GO:0032153 (6.3%) GO:0016020 (5%)" "GO:0004356 (31.3%) GO:0015648 (6.3%)" "glutamine biosynthetic process (30%) regulation of cell shape (6.3%) cell division (6.3%)" "plasma membrane (7.5%) cell division site (6.3%) membrane (5%)" "glutamine synthetase activity (31.3%) lipid-linked peptidoglycan transporter activity (6.3%)" "IPR008146 (14%) IPR027303 (14%) IPR040577 (14%)" "Glutamine synthetase, catalytic domain (14%) Glutamine synthetase, glycine-rich site (14%) Glutamine synthetase, C-terminal (14%)" KELEGAGNELVLLEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.290 (100%) 4-phosphoerythronate dehydrogenase (100%) "GO:0051287 (50%) GO:0016616 (48.2%) GO:0033711 (1.8%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (48.2%) 4-phosphoerythronate dehydrogenase activity (1.8%)" "IPR006139 (30.4%) IPR006140 (30.4%) IPR036291 (30.4%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (30.4%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (30.4%) NAD(P)-binding domain superfamily (30.4%)" NLSSEDLAENLAFTLTHDESNPNLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FGQPLLTGSVLTFEHEENGEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" YAEAEPLLQELTCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" AAYYAGLQLGQQLSNQMVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" YVVLSAPSK Bacteria Bacteria 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0004365 (14.2%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (14.2%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" HMGPDEDVPAGDLGVGGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.4%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.4%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" FEANWDK root "3.4.21.102 (50%) 5.4.2.- (50%)" "C-terminal processing peptidase (50%) Phosphotransferases (phosphomutases) (50%)" "GO:0005975 (19.4%) GO:0006166 (19.4%) GO:0008610 (2.2%)" "GO:0005739 (2.2%) GO:0005811 (2.2%) GO:0005886 (2.2%)" "GO:0000287 (19.4%) GO:0008973 (19.4%) GO:0008168 (2.2%)" "carbohydrate metabolic process (19.4%) purine ribonucleoside salvage (19.4%) lipid biosynthetic process (2.2%)" "mitochondrion (2.2%) lipid droplet (2.2%) plasma membrane (2.2%)" "magnesium ion binding (19.4%) phosphopentomutase activity (19.4%) methyltransferase activity (2.2%)" "IPR005844 (12.6%) IPR016066 (12.6%) IPR005845 (12.1%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (12.6%) Alpha-D-phosphohexomutase, conserved site (12.6%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (12.1%)" QGQAHLNYTGEFTTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.8%) IPR012910 (13.8%) IPR023996 (13.8%)" "TonB-dependent receptor-like, beta-barrel (13.8%) TonB-dependent receptor, plug domain (13.8%) TonB-dependent outer membrane protein, SusC/RagA (13.8%)" LEYKEENLDPTEPLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.- (100%) Transferring other groups (100%) GO:0000455 (33.3%) "GO:0003723 (33.3%) GO:0120159 (33.3%)" enzyme-directed rRNA pseudouridine synthesis (33.3%) "RNA binding (33.3%) rRNA pseudouridine synthase activity (33.3%)" "IPR000748 (11.4%) IPR002942 (11.4%) IPR006145 (11.4%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.4%) RNA-binding S4 domain (11.4%) Pseudouridine synthase, RsuA/RluA-like (11.4%)" SNLDLDVSK root GO:0009263 (3.4%) "GO:0009279 (75.9%) GO:0005634 (3.4%) GO:0005971 (3.4%)" "GO:0004748 (3.4%) GO:0008198 (3.4%) GO:0008270 (3.4%)" deoxyribonucleotide biosynthetic process (3.4%) "cell outer membrane (75.9%) nucleus (3.4%) ribonucleoside-diphosphate reductase complex (3.4%)" "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (3.4%) ferrous iron binding (3.4%) zinc ion binding (3.4%)" "IPR012910 (14.6%) IPR023996 (14.6%) IPR023997 (14.6%)" "TonB-dependent receptor, plug domain (14.6%) TonB-dependent outer membrane protein, SusC/RagA (14.6%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.6%)" WLNLTTNTSFEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" VDMASSLLK root "GO:0009313 (48.1%) GO:0005975 (1.3%)" "GO:0004556 (48.1%) GO:0005506 (1.3%) GO:0016491 (1.3%)" "oligosaccharide catabolic process (48.1%) carbohydrate metabolic process (1.3%)" "alpha-amylase activity (48.1%) iron ion binding (1.3%) oxidoreductase activity (1.3%)" "IPR006047 (24.5%) IPR017853 (23.3%) IPR045857 (23.3%)" "Glycosyl hydrolase family 13, catalytic domain (24.5%) Glycoside hydrolase superfamily (23.3%) Oligo-1,6-glucosidase, domain 2 (23.3%)" VATYDLKPEMSAYEVK Bacteria Bacteria "5.4.2.12 (99.2%) 5.4.2.- (0.6%) 5.4.2.1 (0.2%)" "phosphoglycerate mutase (2,3-diphosphoglycerate-independent) (99.2%) Phosphotransferases (phosphomutases) (0.6%) Transferred entry: 5.4.2.11 and 5.4.2.12 (0.2%)" "GO:0006007 (18.5%) GO:0006096 (18.3%) GO:0043937 (5.3%)" "GO:0005829 (18.4%) GO:0005737 (0%)" "GO:0004619 (18.5%) GO:0030145 (18.5%) GO:0016853 (0.3%)" "glucose catabolic process (18.5%) glycolytic process (18.3%) regulation of sporulation (5.3%)" "cytosol (18.4%) cytoplasm (0%)" "phosphoglycerate mutase activity (18.5%) manganese ion binding (18.5%) isomerase activity (0.3%)" "IPR005995 (20.1%) IPR006124 (20.1%) IPR017850 (20.1%)" "Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent (20.1%) Metalloenzyme (20.1%) Alkaline-phosphatase-like, core domain superfamily (20.1%)" SASHLALECALQTQPNLCLLSEEVEAK Pseudomonadati Bacteria Pseudomonadati 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.5%) GO:0006002 (13.9%)" "GO:0005829 (14.5%) GO:0016020 (0.3%)" "GO:0003872 (14.5%) GO:0047334 (14.5%) GO:0046872 (14.2%)" "response to glucose (14.5%) fructose 6-phosphate metabolic process (13.9%)" "cytosol (14.5%) membrane (0.3%)" "6-phosphofructokinase activity (14.5%) diphosphate-fructose-6-phosphate 1-phosphotransferase activity (14.5%) metal ion binding (14.2%)" "IPR000023 (25.4%) IPR035966 (25.4%) IPR022953 (24.9%)" "Phosphofructokinase domain (25.4%) Phosphofructokinase superfamily (25.4%) ATP-dependent 6-phosphofructokinase (24.9%)" NADQLAPALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.2.4 (100%) D-alanine--D-alanine ligase (100%) "GO:0071555 (14.6%) GO:0008360 (13.9%) GO:0009252 (13.9%)" GO:0005737 (13.9%) "GO:0005524 (14.6%) GO:0008716 (14.6%) GO:0046872 (14.6%)" "cell wall organization (14.6%) regulation of cell shape (13.9%) peptidoglycan biosynthetic process (13.9%)" cytoplasm (13.9%) "ATP binding (14.6%) D-alanine-D-alanine ligase activity (14.6%) metal ion binding (14.6%)" "IPR000291 (14.3%) IPR005905 (14.3%) IPR011095 (14.3%)" "D-alanine--D-alanine ligase/VANA/B/C, conserved site (14.3%) D-alanine--D-alanine ligase (14.3%) D-alanine--D-alanine ligase, C-terminal (14.3%)" MSDEEFLK root 3.6.4.12 (100%) DNA helicase (100%) "GO:0006826 (12.2%) GO:0043171 (4.1%) GO:0051603 (4.1%)" "GO:0009279 (23%) GO:0005829 (5.4%) GO:0005739 (4.1%)" "GO:0004222 (4.1%) GO:0046872 (4.1%) GO:0005524 (2.7%)" "iron ion transport (12.2%) peptide catabolic process (4.1%) proteolysis involved in protein catabolic process (4.1%)" "cell outer membrane (23%) cytosol (5.4%) mitochondrion (4.1%)" "metalloendopeptidase activity (4.1%) metal ion binding (4.1%) ATP binding (2.7%)" "IPR008969 (8.3%) IPR012910 (8.3%) IPR023996 (8.3%)" "Carboxypeptidase-like, regulatory domain superfamily (8.3%) TonB-dependent receptor, plug domain (8.3%) TonB-dependent outer membrane protein, SusC/RagA (8.3%)" VTYSNVKPTTTYLATLYNNDVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR011050 (37.5%) IPR033427 (37.5%) IPR012334 (25%)" "Pectin lyase fold/virulence factor (37.5%) Domain of unknown function DUF5123 (37.5%) Pectin lyase fold (25%)" GSLKEFSENYTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009313 (49.3%) GO:0005975 (1.5%)" GO:0004556 (49.3%) "oligosaccharide catabolic process (49.3%) carbohydrate metabolic process (1.5%)" alpha-amylase activity (49.3%) "IPR006047 (26.8%) IPR017853 (25.2%) IPR045857 (25.2%)" "Glycosyl hydrolase family 13, catalytic domain (26.8%) Glycoside hydrolase superfamily (25.2%) Oligo-1,6-glucosidase, domain 2 (25.2%)" YANVDWQDALFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15.4%) IPR023997 (15.4%) IPR039426 (15.4%)" "TonB-dependent receptor, plug domain (15.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.4%) TonB-dependent receptor-like (15.4%)" EGLQEVYGLPDR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) AFANDCLASEFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.94 (100%) glycerol-3-phosphate dehydrogenase [NAD(P)(+)] (100%) "GO:0005975 (16.7%) GO:0008654 (16.7%) GO:0046168 (16.7%)" GO:0005829 (16.7%) "GO:0051287 (16.7%) GO:0047952 (15.4%) GO:0141153 (1.3%)" "carbohydrate metabolic process (16.7%) phospholipid biosynthetic process (16.7%) glycerol-3-phosphate catabolic process (16.7%)" cytosol (16.7%) "NAD binding (16.7%) glycerol-3-phosphate dehydrogenase [NAD(P)+] activity (15.4%) glycerol-3-phosphate dehydrogenase (NADP+) activity (1.3%)" "IPR006109 (17.3%) IPR006168 (17.3%) IPR011128 (17.3%)" "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal (17.3%) Glycerol-3-phosphate dehydrogenase, NAD-dependent (17.3%) Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal (17.3%)" AAFPQVDVVVGNVATGEAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20.2%) GO:0006183 (20.2%)" "GO:0003938 (20.2%) GO:0046872 (20.2%) GO:0000166 (19.1%)" "GMP biosynthetic process (20.2%) GTP biosynthetic process (20.2%)" "IMP dehydrogenase activity (20.2%) metal ion binding (20.2%) nucleotide binding (19.1%)" "IPR000644 (17.3%) IPR001093 (17.3%) IPR005990 (17.3%)" "CBS domain (17.3%) IMP dehydrogenase/GMP reductase (17.3%) Inosine-5'-monophosphate dehydrogenase (17.3%)" KLPLVSTSAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) "GO:0000272 (33.3%) GO:0046373 (33.3%)" GO:0046556 (33.3%) "polysaccharide catabolic process (33.3%) L-arabinose metabolic process (33.3%)" alpha-L-arabinofuranosidase activity (33.3%) "IPR010720 (26.9%) IPR013780 (24.7%) IPR017853 (24.7%)" "Alpha-L-arabinofuranosidase, C-terminal (26.9%) Glycosyl hydrolase, all-beta (24.7%) Glycoside hydrolase superfamily (24.7%)" VNTPGSVSELKVPENGVLTLLVSPEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) EVAFFEDR Bacteria Bacteria 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (32.3%) GO:0019262 (1%)" "GO:0005737 (32.3%) GO:0005829 (1%)" "GO:0008236 (32.3%) GO:0008747 (1%)" "proteolysis (32.3%) N-acetylneuraminate catabolic process (1%)" "cytoplasm (32.3%) cytosol (1%)" "serine-type peptidase activity (32.3%) N-acetylneuraminate lyase activity (1%)" "IPR005151 (13.9%) IPR011659 (13.9%) IPR012393 (13.9%)" "Tail specific protease (13.9%) WD40-like beta-propeller (13.9%) Tricorn protease (13.9%)" KLDGLDPSFFFDDNGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.4%) IPR041542 (20.4%) IPR051795 (20.4%)" "Glycoside hydrolase, family 43 (20.4%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.4%) Glycosyl Hydrolase Family 43 (20.4%)" ETAYVYPGPLQYWGPSEVCDQTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (15%) GO:0006002 (13.1%)" GO:0005829 (15%) "GO:0003872 (15%) GO:0005524 (14%) GO:0046872 (14%)" "response to glucose (15%) fructose 6-phosphate metabolic process (13.1%)" cytosol (15%) "6-phosphofructokinase activity (15%) ATP binding (14%) metal ion binding (14%)" "IPR000023 (25.4%) IPR011183 (25.4%) IPR035966 (25.4%)" "Phosphofructokinase domain (25.4%) Pyrophosphate-dependent phosphofructokinase PfpB (25.4%) Phosphofructokinase superfamily (25.4%)" DGSLTVGAPAVEGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR001787 (30%) IPR028909 (30%) IPR036164 (30%)" "Large ribosomal subunit protein bL21 (30%) Large ribosomal subunit protein bL21-like (30%) Large ribosomal subunit protein bL21-like superfamily (30%)" CNANPVLLLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" YDLGEVGR root 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) "GO:0006351 (18.7%) GO:0006508 (0.2%) GO:0006412 (0%)" "GO:0000428 (18.6%) GO:0009507 (3.3%) GO:0009536 (2.8%)" "GO:0003677 (18.7%) GO:0003899 (18.7%) GO:0032549 (18.6%)" "DNA-templated transcription (18.7%) proteolysis (0.2%) translation (0%)" "DNA-directed RNA polymerase complex (18.6%) chloroplast (3.3%) plastid (2.8%)" "DNA binding (18.7%) DNA-directed RNA polymerase activity (18.7%) ribonucleoside binding (18.6%)" "IPR007642 (7.9%) IPR015712 (7.9%) IPR007645 (7.9%)" "RNA polymerase Rpb2, domain 2 (7.9%) DNA-directed RNA polymerase, subunit 2 (7.9%) RNA polymerase Rpb2, domain 3 (7.9%)" LGALGFMAHPELSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.1.- (100%) Carboxylic ester hydrolases (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR002018 (20.4%) IPR019826 (20.4%) IPR050309 (20.4%)" "Carboxylesterase, type B (20.4%) Carboxylesterase type B, active site (20.4%) Type-B Carboxylesterase/Lipase (20.4%)" AETHNFPTTVEPFNGAATGTGGELR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.1%) GO:0006164 (0.9%)" GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" "'de novo' IMP biosynthetic process (19.1%) purine nucleotide biosynthetic process (0.9%)" cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010918 (11.2%) IPR041609 (11.2%) IPR055181 (11.2%)" "PurM-like, C-terminal domain (11.2%) Phosphoribosylformylglycinamidine synthase, linker domain (11.2%) FGAR-AT, PurM N-terminal-like domain (11.2%)" NNTFQGTDTGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (43.9%) "GO:0004650 (43.9%) GO:0004557 (12.3%)" carbohydrate metabolic process (43.9%) "polygalacturonase activity (43.9%) alpha-galactosidase activity (12.3%)" "IPR000743 (20.7%) IPR006626 (20.7%) IPR051801 (20.7%)" "Glycoside hydrolase, family 28 (20.7%) Parallel beta-helix repeat (20.7%) Glycosyl_Hydrolase_28_Enzymes (20.7%)" MSYATSDENLVEALKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.6.1.- (97.1%) 2.6.1.1 (2.9%)" "Transaminases (97.1%) aspartate transaminase (2.9%)" GO:0006520 (33.3%) "GO:0008483 (33.3%) GO:0030170 (33.3%)" amino acid metabolic process (33.3%) "transaminase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR015422 (17%) IPR015424 (17%) IPR004838 (16.5%)" "Pyridoxal phosphate-dependent transferase, small domain (17%) Pyridoxal phosphate-dependent transferase (17%) Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.5%)" ENVSFDGLVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR002314 (11.3%) IPR004154 (11.3%) IPR004499 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Anticodon-binding (11.3%) Proline-tRNA ligase, class IIa, archaeal-type (11.3%)" DLQPEEKDMVSSLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR025874 (89.7%) IPR011990 (10.3%)" "Double zinc ribbon (89.7%) Tetratricopeptide-like helical domain superfamily (10.3%)" FLEYESVEEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.3.1.98 (100%) UDP-N-acetylmuramate dehydrogenase (100%) "GO:0008360 (14.2%) GO:0009252 (14.2%) GO:0051301 (14.2%)" GO:0005829 (14.2%) "GO:0008762 (14.2%) GO:0071949 (14.2%) GO:0050660 (0.5%)" "regulation of cell shape (14.2%) peptidoglycan biosynthetic process (14.2%) cell division (14.2%)" cytosol (14.2%) "UDP-N-acetylmuramate dehydrogenase activity (14.2%) FAD binding (14.2%) flavin adenine dinucleotide binding (0.5%)" "IPR003170 (12.6%) IPR006094 (12.6%) IPR011601 (12.6%)" "UDP-N-acetylenolpyruvoylglucosamine reductase (12.6%) FAD linked oxidase, N-terminal (12.6%) UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal (12.6%)" AYAEADPTLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (13%) GO:0006261 (12%)" "GO:0005694 (12%) GO:0005737 (12%)" "GO:0003677 (13%) GO:0005524 (13%) GO:0034335 (12%)" "DNA topological change (13%) DNA-templated DNA replication (12%)" "chromosome (12%) cytoplasm (12%)" "DNA binding (13%) ATP binding (13%) DNA negative supercoiling activity (12%)" "IPR001241 (8.1%) IPR006171 (8.1%) IPR013506 (8.1%)" "DNA topoisomerase, type IIA (8.1%) TOPRIM domain (8.1%) DNA topoisomerase, type IIA, subunit B, domain 2 (8.1%)" EKPWGTNHAVLMAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016740 (100%) transferase activity (100%) "IPR029044 (75%) IPR005835 (25%)" "Nucleotide-diphospho-sugar transferases (75%) Nucleotidyl transferase domain (25%)" QVYNLYSVVVTPDESQVYTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SGKLDPVLGR root "GO:0034605 (18.1%) GO:0042026 (15.6%) GO:0006508 (3.3%)" "GO:0005737 (14.8%) GO:0005829 (3.2%) GO:0005759 (0.3%)" "GO:0005524 (18.3%) GO:0016887 (18.3%) GO:0008233 (3.3%)" "cellular response to heat (18.1%) protein refolding (15.6%) proteolysis (3.3%)" "cytoplasm (14.8%) cytosol (3.2%) mitochondrial matrix (0.3%)" "ATP binding (18.3%) ATP hydrolysis activity (18.3%) peptidase activity (3.3%)" "IPR050130 (8.7%) IPR027417 (8.6%) IPR003959 (8.6%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.7%) P-loop containing nucleoside triphosphate hydrolase (8.6%) ATPase, AAA-type, core (8.6%)" LNDEELLTLGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.1.- (50%) 2.7.1.4 (50%)" "Phosphotransferases with an alcohol group as acceptor (50%) fructokinase (50%)" "GO:0016301 (97.2%) GO:0008865 (2.8%)" "kinase activity (97.2%) fructokinase activity (2.8%)" "IPR011611 (30.8%) IPR050306 (30.8%) IPR029056 (29.1%)" "Carbohydrate kinase PfkB (30.8%) PfkB Carbohydrate Kinase (30.8%) Ribokinase-like (29.1%)" VYVNPEGNVDWHGLASQPQYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) "GO:0006465 (32.6%) GO:0006508 (1.1%)" GO:0016020 (32.6%) GO:0008236 (33.7%) "signal peptide processing (32.6%) proteolysis (1.1%)" membrane (32.6%) serine-type peptidase activity (33.7%) "IPR002142 (17.2%) IPR047217 (17.2%) IPR004634 (16.7%)" "Peptidase S49 (17.2%) Signal peptide peptidase A, N-terminal (17.2%) Peptidase S49, protease IV (16.7%)" LPFVWLSNNFTNTGVQTSSYSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" ELTLTGCDSMDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0005886 (25%) "GO:0008137 (25%) GO:0048038 (25%) GO:0051287 (25%)" plasma membrane (25%) "NADH dehydrogenase (ubiquinone) activity (25%) quinone binding (25%) NAD binding (25%)" "IPR001135 (20%) IPR001268 (20%) IPR022885 (20%)" "NADH-quinone oxidoreductase, subunit D (20%) NADH:ubiquinone oxidoreductase, 30kDa subunit (20%) NAD(P)H-quinone oxidoreductase subunit D/H (20%)" VDFGVQYTHQFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DFVEVFNAEAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (33.2%) "GO:0003921 (33.2%) GO:0005524 (33.2%) GO:0016740 (0.3%)" cytosol (33.2%) "GMP synthase activity (33.2%) ATP binding (33.2%) transferase activity (0.3%)" "IPR001674 (12.7%) IPR025777 (12.7%) IPR017926 (12.6%)" "GMP synthase, C-terminal (12.7%) GMP synthetase ATP pyrophosphatase domain (12.7%) Glutamine amidotransferase (12.6%)" LMGYTVLQASETPGLGAK Pseudomonadati Bacteria Pseudomonadati 7.-.-.- (100%) Translocases (100%) GO:0022900 (25%) GO:0005886 (25%) "GO:0009055 (25%) GO:0010181 (25%)" electron transport chain (25%) plasma membrane (25%) "electron transfer activity (25%) FMN binding (25%)" "IPR007329 (50%) IPR010209 (50%)" "FMN-binding (50%) Ion-translocating oxidoreductase complex, subunit RnfG/RsxG (50%)" TLKEDLLEGFK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006355 (20%) GO:0000160 (0.1%)" "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" "regulation of DNA-templated transcription (20%) phosphorelay signal transduction system (0.1%)" "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (17.6%) IPR039420 (17.6%) IPR001867 (17.5%)" "Signal transduction response regulator, receiver domain (17.6%) Transcriptional regulatory protein WalR-like (17.6%) OmpR/PhoB-type DNA-binding domain (17.5%)" TTLAESMLFEAGVLKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000795 (7.8%) IPR005225 (7.8%) IPR041095 (7.8%)" "Translational (tr)-type GTP-binding domain (7.8%) Small GTP-binding domain (7.8%) Elongation Factor G, domain II (7.8%)" EFLQGEFNYLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.4 (100%) aspartate kinase (100%) "GO:0009089 (17.8%) GO:0009090 (17.8%) GO:0009088 (11%)" GO:0005829 (17.8%) "GO:0004072 (17.8%) GO:0005524 (17.8%)" "lysine biosynthetic process via diaminopimelate (17.8%) homoserine biosynthetic process (17.8%) threonine biosynthetic process (11%)" cytosol (17.8%) "aspartate kinase activity (17.8%) ATP binding (17.8%)" "IPR001048 (14.3%) IPR001341 (14.3%) IPR005260 (14.3%)" "Aspartate/glutamate/uridylate kinase (14.3%) Aspartate kinase (14.3%) Aspartate kinase, monofunctional class (14.3%)" NLYTNQFHYLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.3%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.3%)" MDENPTELLPEELRNPGEGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (25%) "GO:0046872 (25%) GO:0051539 (25%) GO:0004333 (23.9%)" tricarboxylic acid cycle (25%) "metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%) fumarate hydratase activity (23.9%)" "IPR004646 (20.4%) IPR004647 (20.4%) IPR051208 (20.4%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (20.4%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (20.4%) Class-I Fumarase/Tartrate Dehydratase (20.4%)" WGATQSDYSNGTQFLYDGSYLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" HPDEDVLLDVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006108 (16.7%) "GO:0004470 (16.7%) GO:0016616 (16.7%) GO:0016746 (16.7%)" malate metabolic process (16.7%) "malic enzyme activity (16.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (16.7%) acyltransferase activity (16.7%)" "IPR002505 (9.1%) IPR012188 (9.1%) IPR012301 (9.1%)" "Phosphate acetyl/butaryl transferase (9.1%) NAD(P)-dependent malic enzyme (9.1%) Malic enzyme, N-terminal domain (9.1%)" TLLWNGPAGVFEFDNFAGGSK root 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006096 (15.2%) GO:0006094 (14.8%) GO:0000050 (0.4%)" "GO:0005829 (14.8%) GO:0005739 (0.9%) GO:0005737 (0.4%)" "GO:0004618 (15.2%) GO:0005524 (15.2%) GO:0043531 (14.8%)" "glycolytic process (15.2%) gluconeogenesis (14.8%) urea cycle (0.4%)" "cytosol (14.8%) mitochondrion (0.9%) cytoplasm (0.4%)" "phosphoglycerate kinase activity (15.2%) ATP binding (15.2%) ADP binding (14.8%)" "IPR001576 (27.1%) IPR015824 (27.1%) IPR036043 (27.1%)" "Phosphoglycerate kinase (27.1%) Phosphoglycerate kinase, N-terminal (27.1%) Phosphoglycerate kinase superfamily (27.1%)" ATNPFLLYNAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" YQSMLSEETKDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (58.3%) IPR009057 (41.7%)" "AraC-like, DNA binding HTH domain (58.3%) Homedomain-like superfamily (41.7%)" NNVTLASAPLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR041542 (20.7%) IPR051795 (20.7%) IPR006710 (20.1%)" "Beta-xylosidase, C-terminal Concanavalin A-like domain (20.7%) Glycosyl Hydrolase Family 43 (20.7%) Glycoside hydrolase, family 43 (20.1%)" HVMLSYYGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (11.9%) IPR012910 (11.9%) IPR023996 (11.9%)" "TonB-dependent receptor-like, beta-barrel (11.9%) TonB-dependent receptor, plug domain (11.9%) TonB-dependent outer membrane protein, SusC/RagA (11.9%)" LLLFDDLLASGNSVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (51.4%) IPR029057 (48.6%)" "Phosphoribosyltransferase domain (51.4%) Phosphoribosyltransferase-like (48.6%)" FTSCENVLVQGVTLLNSPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (44.1%) "GO:0004650 (44.1%) GO:0004557 (11.9%)" carbohydrate metabolic process (44.1%) "polygalacturonase activity (44.1%) alpha-galactosidase activity (11.9%)" "IPR000743 (20.6%) IPR006626 (20.6%) IPR051801 (20.6%)" "Glycoside hydrolase, family 28 (20.6%) Parallel beta-helix repeat (20.6%) Glycosyl_Hydrolase_28_Enzymes (20.6%)" ELLPVSEHYGGLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0140359 (50%) plasma membrane (50%) ABC-type transporter activity (50%) "IPR013525 (50%) IPR051449 (50%)" "ABC-2 type transporter, transmembrane domain (50%) ABC-2 integral membrane transporter component (50%)" RLNDLEALAMSYPGVTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.9%) GO:0005886 (20%) "GO:0003723 (20%) GO:0016787 (20%) GO:0004521 (19.9%)" mRNA catabolic process (19.9%) plasma membrane (20%) "RNA binding (20%) hydrolase activity (20%) RNA endonuclease activity (19.9%)" "IPR006674 (12.6%) IPR006675 (12.6%) IPR003607 (12.5%)" "HD domain (12.6%) HDIG domain (12.6%) HD/PDEase domain (12.5%)" GEEWLPSAPLHVLLYK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.6%) "GO:0005829 (16.6%) GO:0016020 (0.4%)" "GO:0000049 (16.6%) GO:0004818 (16.6%) GO:0005524 (16.6%)" glutamyl-tRNA aminoacylation (16.6%) "cytosol (16.6%) membrane (0.4%)" "tRNA binding (16.6%) glutamate-tRNA ligase activity (16.6%) ATP binding (16.6%)" "IPR000924 (9.6%) IPR004527 (9.6%) IPR008925 (9.6%)" "Glutamyl/glutaminyl-tRNA synthetase (9.6%) Glutamate-tRNA ligase, bacterial/mitochondrial (9.6%) Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily (9.6%)" NPEQLELLR root "1.97.1.- (87.5%) 1.14.-.- (12.5%)" "Other oxidoreductases (87.5%) Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporated need not be derived from O2 (12.5%)" "GO:1902600 (10.3%) GO:0006813 (9.7%) GO:0006707 (0.7%)" "GO:0005886 (10.3%) GO:0012505 (10.3%) GO:0016020 (0.7%)" "GO:0015297 (10.3%) GO:0008324 (9.7%) GO:0004748 (5.5%)" "proton transmembrane transport (10.3%) potassium ion transport (9.7%) cholesterol catabolic process (0.7%)" "plasma membrane (10.3%) endomembrane system (10.3%) membrane (0.7%)" "antiporter activity (10.3%) monoatomic cation transmembrane transporter activity (9.7%) ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (5.5%)" "IPR003148 (11.8%) IPR004771 (11.8%) IPR006153 (11.8%)" "Regulator of K+ conductance, N-terminal lobe (11.8%) K+/H+ exchanger (11.8%) Cation/H+ exchanger, transmembrane domain (11.8%)" YLDPASLK root "2.7.11.1 (71.4%) 2.3.1.157 (7.1%) 2.7.7.23 (7.1%)" "non-specific serine/threonine protein kinase (71.4%) glucosamine-1-phosphate N-acetyltransferase (7.1%) UDP-N-acetylglucosamine diphosphorylase (7.1%)" "GO:0006542 (8.4%) GO:0006351 (2.6%) GO:0006313 (1.3%)" "GO:0016020 (5.8%) GO:0000139 (0.6%) GO:0005737 (0.6%)" "GO:0005524 (23.2%) GO:0004672 (16.1%) GO:0004356 (9%)" "glutamine biosynthetic process (8.4%) DNA-templated transcription (2.6%) DNA transposition (1.3%)" "membrane (5.8%) Golgi membrane (0.6%) cytoplasm (0.6%)" "ATP binding (23.2%) protein kinase activity (16.1%) glutamine synthetase activity (9%)" "IPR000719 (10.6%) IPR011009 (10.6%) IPR017441 (9.4%)" "Protein kinase domain (10.6%) Protein kinase-like domain superfamily (10.6%) Protein kinase, ATP binding site (9.4%)" YESATPNVPADAGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013783 (50%) IPR024361 (50%)" "Immunoglobulin-like fold (50%) Bacteroidetes-Associated Carbohydrate-binding Often N-terminal (50%)" CVAMDNTDGLQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (23.1%) GO:0045259 (23.1%)" "GO:0005524 (23.1%) GO:0046933 (23.1%) GO:0016787 (7.7%)" "plasma membrane (23.1%) proton-transporting ATP synthase complex (23.1%)" "ATP binding (23.1%) proton-transporting ATP synthase activity, rotational mechanism (23.1%) hydrolase activity (7.7%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" WNPGYLNVPLTLNYYPVAGLALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR027385 (84.6%) IPR011250 (7.7%) IPR025665 (7.7%)" "Outer membrane protein, beta-barrel domain (84.6%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (7.7%) Outer membrane protein, beta-barrel domain 2 (7.7%)" VLTFPDEGSEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VTLLNGPHTVLSPVTYLSGVNLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.4%) GO:0005829 (32.4%) "GO:0008926 (32.4%) GO:0009026 (2.8%)" mannitol catabolic process (32.4%) cytosol (32.4%) "mannitol-1-phosphate 5-dehydrogenase activity (32.4%) tagaturonate reductase activity (2.8%)" "IPR013118 (21.7%) IPR013131 (21.7%) IPR008927 (18.9%)" "Mannitol dehydrogenase, C-terminal (21.7%) Mannitol dehydrogenase, N-terminal (21.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (18.9%)" ALLALDSPSLQLK Pseudomonadati Bacteria Pseudomonadati "GO:0007059 (25.2%) GO:0045881 (25.2%)" GO:0005694 (25.2%) GO:0003677 (24.4%) "chromosome segregation (25.2%) positive regulation of sporulation resulting in formation of a cellular spore (25.2%)" chromosome (25.2%) DNA binding (24.4%) "IPR041468 (17.1%) IPR050336 (17.1%) IPR003115 (16.6%)" "ParB/Spo0J, HTH domain (17.1%) Chromosome-partitioning and nucleoid occlusion protein (17.1%) ParB-like, N-terminal domain (16.6%)" GLYSYSSGFNEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) NESLANLAR root "1.3.99.1 (90.9%) 1.3.5.1 (9.1%)" "Deleted entry (90.9%) succinate dehydrogenase (9.1%)" "GO:0009060 (23.7%) GO:0022904 (23.7%) GO:0005975 (0.3%)" GO:0016020 (0.3%) "GO:0009055 (23.7%) GO:0051537 (23.7%) GO:0016491 (3.3%)" "aerobic respiration (23.7%) respiratory electron transport chain (23.7%) carbohydrate metabolic process (0.3%)" membrane (0.3%) "electron transfer activity (23.7%) 2 iron, 2 sulfur cluster binding (23.7%) oxidoreductase activity (3.3%)" "IPR009051 (13.8%) IPR017896 (13.8%) IPR006058 (13.7%)" "Alpha-helical ferredoxin (13.8%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (13.8%) 2Fe-2S ferredoxin, iron-sulphur binding site (13.7%)" ELFQQQTGETTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) TSLAAALAAR root "2.5.1.75 (94.6%) 3.5.1.4 (2.7%) 6.3.4.15 (2.7%)" "tRNA dimethylallyltransferase (94.6%) amidase (2.7%) biotin--[biotin carboxyl-carrier protein] ligase (2.7%)" "GO:0006400 (30.6%) GO:0006355 (0.9%)" "GO:0016020 (1.9%) GO:0005737 (0.9%)" "GO:0005524 (31.5%) GO:0052381 (30.6%) GO:0003677 (0.9%)" "tRNA modification (30.6%) regulation of DNA-templated transcription (0.9%)" "membrane (1.9%) cytoplasm (0.9%)" "ATP binding (31.5%) tRNA dimethylallyltransferase activity (30.6%) DNA binding (0.9%)" "IPR018022 (28.9%) IPR039657 (28.9%) IPR027417 (27.2%)" "IPP transferase (28.9%) Dimethylallyltransferase (28.9%) P-loop containing nucleoside triphosphate hydrolase (27.2%)" LWGSFPVLTTLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.8%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.8%)" LQTAFETGK root "GO:0044718 (30.4%) GO:0001080 (1.8%) GO:0006351 (1.8%)" "GO:0009279 (30.4%) GO:0005634 (1.8%)" "GO:0015344 (30.4%) GO:0003677 (1.8%) GO:0008270 (1.8%)" "siderophore transmembrane transport (30.4%) nitrogen catabolite activation of transcription from RNA polymerase II promoter (1.8%) DNA-templated transcription (1.8%)" "cell outer membrane (30.4%) nucleus (1.8%)" "siderophore uptake transmembrane transporter activity (30.4%) DNA binding (1.8%) zinc ion binding (1.8%)" "IPR000531 (20%) IPR012910 (20%) IPR039426 (20%)" "TonB-dependent receptor-like, beta-barrel (20%) TonB-dependent receptor, plug domain (20%) TonB-dependent receptor-like (20%)" LANQLYDEVKR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.-.- (100%) Acting on acid anhydrides (100%) GO:0016787 (100%) hydrolase activity (100%) "IPR025669 (33.3%) IPR027417 (33.3%) IPR050678 (33.3%)" "AAA domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) DNA Partitioning ATPase (33.3%)" AVGESVQKPLLYYR root "5.1.3.2 (99.5%) 5.1.3.- (0.5%)" "UDP-glucose 4-epimerase (99.5%) Acting on carbohydrates and derivatives (0.5%)" "GO:0006012 (32.4%) GO:0033499 (0.8%)" GO:0005829 (33.2%) "GO:0003978 (33.2%) GO:0003974 (0.2%) GO:0016853 (0.2%)" "galactose metabolic process (32.4%) galactose catabolic process via UDP-galactose, Leloir pathway (0.8%)" cytosol (33.2%) "UDP-glucose 4-epimerase activity (33.2%) UDP-N-acetylglucosamine 4-epimerase activity (0.2%) isomerase activity (0.2%)" "IPR005886 (33.4%) IPR036291 (33.2%) IPR016040 (19.3%)" "UDP-glucose 4-epimerase (33.4%) NAD(P)-binding domain superfamily (33.2%) NAD(P)-binding domain (19.3%)" NLVMYNLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.6.3.- (100%) With oxygen as acceptor (100%) "GO:0010181 (25.7%) GO:0009055 (24.8%) GO:0016491 (24.8%)" "FMN binding (25.7%) electron transfer activity (24.8%) oxidoreductase activity (24.8%)" "IPR001279 (17%) IPR008254 (17%) IPR045761 (17%)" "Metallo-beta-lactamase (17%) Flavodoxin/nitric oxide synthase (17%) ODP domain (17%)" ADETLLEFMQTDKYNQQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LLFSMVGVSK Pseudomonadati Bacteria Pseudomonadati 3.6.1.- (100%) In phosphorus-containing anhydrides (100%) "GO:0045900 (12.6%) GO:0006412 (12.4%)" "GO:0005737 (12.4%) GO:0016020 (0.1%)" "GO:0005524 (12.6%) GO:0016887 (12.6%) GO:0000049 (12.5%)" "negative regulation of translational elongation (12.6%) translation (12.4%)" "cytoplasm (12.4%) membrane (0.1%)" "ATP binding (12.6%) ATP hydrolysis activity (12.6%) tRNA binding (12.5%)" "IPR003439 (16.8%) IPR022374 (16.8%) IPR027417 (16.8%)" "ABC transporter-like, ATP-binding domain (16.8%) Energy-dependent translational throttle protein EttA (16.8%) P-loop containing nucleoside triphosphate hydrolase (16.8%)" YMDTPQTNPEGYKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.3%) IPR002469 (25.3%) IPR050278 (25.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.3%) Dipeptidylpeptidase IV, N-terminal domain (25.3%) Serine protease S9B/DPPIV (25.3%)" LGLSWDEFLGMGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.1 (81.3%) 2.4.1.8 (18.8%)" "glycogen phosphorylase (81.3%) maltose phosphorylase (18.8%)" GO:0005975 (33%) "GO:0008184 (33%) GO:0030170 (33%) GO:0050082 (1%)" carbohydrate metabolic process (33%) "glycogen phosphorylase activity (33%) pyridoxal phosphate binding (33%) maltose phosphorylase activity (1%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" QSELSNSPEVLRR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.8.3.- (100%) CoA-transferases (100%) "GO:0006083 (31.4%) GO:0006084 (5.8%)" "GO:0003986 (31.4%) GO:0008775 (31.4%)" "acetate metabolic process (31.4%) acetyl-CoA metabolic process (5.8%)" "acetyl-CoA hydrolase activity (31.4%) acetate CoA-transferase activity (31.4%)" "IPR026888 (19.6%) IPR046433 (19.6%) IPR003702 (19.1%)" "Acetyl-CoA hydrolase/transferase, C-terminal domain (19.6%) Acetyl-CoA hydrolase/transferase (19.6%) Acetyl-CoA hydrolase/transferase, N-terminal (19.1%)" LADNVDHYNNVLQLTVGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR027385 (83.3%) IPR011250 (16.7%)" "Outer membrane protein, beta-barrel domain (83.3%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (16.7%)" VSTDKTDLVMQVSPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.7%) IPR031704 (12.7%) IPR031705 (12.7%)" "Glycoside hydrolase family 36 (12.7%) Glycosyl hydrolase family 36, N-terminal (12.7%) Glycosyl hydrolase family 36, C-terminal (12.7%)" TSLESLPEELKFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004035 (100%) alkaline phosphatase activity (100%) "IPR002591 (33.7%) IPR026263 (33.7%) IPR017850 (32.6%)" "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase (33.7%) Alkaline phosphatase, prokaryotic (33.7%) Alkaline-phosphatase-like, core domain superfamily (32.6%)" EVGLDTGKDYNLLSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (3.2%) GO:0009279 (93.5%) GO:0015344 (3.2%) siderophore transmembrane transport (3.2%) cell outer membrane (93.5%) siderophore uptake transmembrane transporter activity (3.2%) "IPR012910 (12.9%) IPR023997 (12.9%) IPR039426 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%) TonB-dependent receptor-like (12.9%)" VSGVQLMSNSGSASAGSTLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (6.1%) GO:0009279 (87.9%) GO:0015344 (6.1%) siderophore transmembrane transport (6.1%) cell outer membrane (87.9%) siderophore uptake transmembrane transporter activity (6.1%) "IPR012910 (12.2%) IPR023997 (12.2%) IPR039426 (12.2%)" "TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.2%) TonB-dependent receptor-like (12.2%)" RVNLEANTVDVELAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015031 (50%) GO:0005886 (50%) protein transport (50%) plasma membrane (50%) IPR003849 (100%) Preprotein translocase YajC (100%) LLREEGTNSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (44.3%) "GO:0015926 (44.3%) GO:0031218 (11.5%)" pectin catabolic process (44.3%) "glucosidase activity (44.3%) arabinogalactan endo-1,4-beta-galactosidase activity (11.5%)" "IPR011683 (51.9%) IPR017853 (48.1%)" "Glycosyl hydrolase family 53 (51.9%) Glycoside hydrolase superfamily (48.1%)" EQSTSAVSVLTSESTNKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" TGVDPDTLDALLVTTTTPDYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (20%)" GO:0005737 (20%) "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (20%)" cytoplasm (20%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" QLYPDLAVLDAFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0000917 (14.3%) GO:0043093 (14.3%) GO:0051258 (14.3%)" "GO:0005737 (14.3%) GO:0032153 (14.3%)" "GO:0003924 (14.3%) GO:0005525 (14.3%)" "division septum assembly (14.3%) FtsZ-dependent cytokinesis (14.3%) protein polymerization (14.3%)" "cytoplasm (14.3%) cell division site (14.3%)" "GTPase activity (14.3%) GTP binding (14.3%)" "IPR000158 (11.7%) IPR003008 (11.7%) IPR018316 (11.7%)" "Cell division protein FtsZ (11.7%) Tubulin/FtsZ, GTPase domain (11.7%) Tubulin/FtsZ, 2-layer sandwich domain (11.7%)" NLNPVELWR root 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (32.4%) IPR002933 (32.4%) IPR011650 (32.4%)" "Peptidase M20C, Xaa-His dipeptidase (32.4%) Peptidase M20 (32.4%) Peptidase M20, dimerisation domain (32.4%)" LENAVLSALENTPPELYADLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000902 (24.6%) GO:0008360 (24.6%)" GO:0005737 (25.1%) "GO:0005524 (24.6%) GO:0016787 (1%)" "cell morphogenesis (24.6%) regulation of cell shape (24.6%)" cytoplasm (25.1%) "ATP binding (24.6%) hydrolase activity (1%)" "IPR043129 (31.7%) IPR056546 (31.7%) IPR004753 (31.1%)" "ATPase, nucleotide binding domain (31.7%) MreB/MamK-like (31.7%) Cell shape determining protein MreB (31.1%)" WSNLKDDGTTASNTADAGVETDYPLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" VGQVLSGEVYQVWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006353 (19.6%) GO:0031564 (19.6%)" GO:0005829 (19.6%) "GO:0003700 (19.6%) GO:0003723 (19.6%) GO:0003746 (2%)" "DNA-templated transcription termination (19.6%) transcription antitermination (19.6%)" cytosol (19.6%) "DNA-binding transcription factor activity (19.6%) RNA binding (19.6%) translation elongation factor activity (2%)" "IPR003029 (11.6%) IPR010213 (11.6%) IPR013735 (11.6%)" "S1 domain (11.6%) Transcription factor NusA (11.6%) Transcription factor NusA, N-terminal (11.6%)" ADLTPNFSQDNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20.8%) GO:0022627 (20.8%) "GO:0003735 (20.8%) GO:0019843 (20.8%) GO:0003729 (16.7%)" translation (20.8%) cytosolic small ribosomal subunit (20.8%) "structural constituent of ribosome (20.8%) rRNA binding (20.8%) mRNA binding (16.7%)" "IPR001351 (11.1%) IPR004044 (11.1%) IPR004087 (11.1%)" "Small ribosomal subunit protein uS3, C-terminal (11.1%) K Homology domain, type 2 (11.1%) K Homology domain (11.1%)" LATDPFMGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0032790 (20.1%) GO:0006412 (0.2%)" GO:0005737 (19.7%) "GO:0005525 (20.1%) GO:0003746 (19.9%) GO:0003924 (19.9%)" "ribosome disassembly (20.1%) translation (0.2%)" cytoplasm (19.7%) "GTP binding (20.1%) translation elongation factor activity (19.9%) GTPase activity (19.9%)" "IPR004161 (6.3%) IPR000640 (6.3%) IPR000795 (6.3%)" "Translation elongation factor EFTu-like, domain 2 (6.3%) Elongation factor EFG, domain V-like (6.3%) Translational (tr)-type GTP-binding domain (6.3%)" AGDVYQALAASEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019707 (52.6%) IPR036388 (47.4%)" "MJ1608-like (52.6%) Winged helix-like DNA-binding domain superfamily (47.4%)" FVDVLGTSK Bacteria Bacteria GO:0006412 (23.4%) "GO:0022625 (16.8%) GO:0005840 (6.5%) GO:1990904 (6.5%)" "GO:0003735 (23.4%) GO:0019843 (23.4%)" translation (23.4%) "cytosolic large ribosomal subunit (16.8%) ribosome (6.5%) ribonucleoprotein complex (6.5%)" "structural constituent of ribosome (23.4%) rRNA binding (23.4%)" "IPR000597 (25.1%) IPR009000 (25.1%) IPR019927 (25.1%)" "Large ribosomal subunit protein uL3 (25.1%) Translation protein, beta-barrel domain superfamily (25.1%) Large ribosomal subunit protein uL3, bacteria/organella (25.1%)" SYLAEGEVLDVPTR Bacteria Bacteria GO:0006004 (33.3%) GO:0005737 (33.3%) GO:0008736 (33.3%) fucose metabolic process (33.3%) cytoplasm (33.3%) L-fucose isomerase activity (33.3%) "IPR015888 (50.8%) IPR009015 (49.2%)" "L-fucose isomerase, C-terminal (50.8%) L-fucose isomerase, N-terminal/central domain superfamily (49.2%)" LAHLLEEAK root "3.5.2.5 (50%) 1.2.7.1 (25%) 2.5.1.18 (25%)" "allantoinase (50%) pyruvate synthase (25%) glutathione transferase (25%)" "GO:0006979 (7.6%) GO:0022900 (7.6%) GO:0044281 (7.4%)" "GO:0005739 (4.1%) GO:0005874 (4.1%) GO:0016020 (4.1%)" "GO:0005506 (7.6%) GO:0030976 (7.6%) GO:0051539 (7.6%)" "response to oxidative stress (7.6%) electron transport chain (7.6%) small molecule metabolic process (7.4%)" "mitochondrion (4.1%) microtubule (4.1%) membrane (4.1%)" "iron ion binding (7.6%) thiamine pyrophosphate binding (7.6%) 4 iron, 4 sulfur cluster binding (7.6%)" "IPR002880 (5.6%) IPR011766 (5.6%) IPR011895 (5.6%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (5.6%) Thiamine pyrophosphate enzyme, TPP-binding (5.6%) Pyruvate-flavodoxin oxidoreductase (5.6%)" GDFAHEVFAEVVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "4.1.2.14 (51.9%) 4.1.3.16 (48.1%)" "2-dehydro-3-deoxy-phosphogluconate aldolase (51.9%) 4-hydroxy-2-oxoglutarate aldolase (48.1%)" "GO:0016829 (42.9%) GO:0008675 (29.6%) GO:0008700 (27.6%)" "lyase activity (42.9%) 2-dehydro-3-deoxy-phosphogluconate aldolase activity (29.6%) (R,S)-4-hydroxy-2-oxoglutarate aldolase activity (27.6%)" "IPR000887 (50%) IPR013785 (50%)" "KDPG/KHG aldolase (50%) Aldolase-type TIM barrel (50%)" GFQYPVALEGALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (12.6%) GO:0006047 (12.6%) GO:0006487 (12.6%)" GO:0005829 (12.6%) "GO:0004360 (12.6%) GO:0097367 (12.6%)" "fructose 6-phosphate metabolic process (12.6%) UDP-N-acetylglucosamine metabolic process (12.6%) protein N-linked glycosylation (12.6%)" cytosol (12.6%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.6%) carbohydrate derivative binding (12.6%)" "IPR001347 (13%) IPR035466 (13%) IPR035490 (13%)" "SIS domain (13%) GlmS/AgaS, SIS domain 1 (13%) GlmS/FrlB, SIS domain 2 (13%)" PTLSQLVR root "4.1.3.44 (66.7%) 2.4.2.17 (33.3%)" "tRNA 4-demethylwyosine synthase (AdoMet-dependent) (66.7%) ATP phosphoribosyltransferase (33.3%)" "GO:0006412 (19.7%) GO:0007031 (0.2%) GO:0007264 (0.1%)" "GO:0015935 (19.6%) GO:0016020 (0.3%) GO:0005737 (0.2%)" "GO:0003735 (19.7%) GO:0019843 (19.5%) GO:0000049 (18.9%)" "translation (19.7%) peroxisome organization (0.2%) small GTPase-mediated signal transduction (0.1%)" "small ribosomal subunit (19.6%) membrane (0.3%) cytoplasm (0.2%)" "structural constituent of ribosome (19.7%) rRNA binding (19.5%) tRNA binding (18.9%)" "IPR005679 (31.1%) IPR006032 (31.1%) IPR012340 (31.1%)" "Ribosomal protein uS12, bacteria (31.1%) Small ribosomal subunit protein uS12 (31.1%) Nucleic acid-binding, OB-fold (31.1%)" QMNALSVLGLLSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" "GO:0008880 (33.3%) GO:0016853 (0.2%)" "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" "glucuronate isomerase activity (33.3%) isomerase activity (0.2%)" "IPR003766 (50.3%) IPR032466 (49.7%)" "Uronate isomerase (50.3%) Metal-dependent hydrolase (49.7%)" ALVAVPEVGEVYEGTVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" LGLYSDDADNQYFPYLRPQESGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.8%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.8%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" YLAPQQVESLLLVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016020 (49.3%) GO:0005783 (1.4%)" GO:0004467 (49.3%) "membrane (49.3%) endoplasmic reticulum (1.4%)" long-chain fatty acid-CoA ligase activity (49.3%) "IPR000873 (33.7%) IPR020845 (33.7%) IPR042099 (32.7%)" "AMP-dependent synthetase/ligase domain (33.7%) AMP-binding, conserved site (33.7%) ANL, N-terminal domain (32.7%)" SLFALGEAPLPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.99.17 (100%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase (100%) GO:0002099 (34.4%) GO:0005737 (31.3%) GO:0051075 (34.4%) tRNA wobble guanine modification (34.4%) cytoplasm (31.3%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity (34.4%) "IPR003699 (26.8%) IPR036100 (24.4%) IPR042118 (24.4%)" "S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA (26.8%) S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily (24.4%) QueA, domain 1 (24.4%)" HLNLDTNLNTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" VVVVEDLLSTGGSSLK Bacteria Bacteria 2.4.2.10 (100%) orotate phosphoribosyltransferase (100%) "GO:0019856 (25.1%) GO:0044205 (25.1%) GO:0006222 (0.1%)" "GO:0004588 (25.1%) GO:0000287 (24.4%) GO:0016757 (0.1%)" "pyrimidine nucleobase biosynthetic process (25.1%) 'de novo' UMP biosynthetic process (25.1%) UMP biosynthetic process (0.1%)" "orotate phosphoribosyltransferase activity (25.1%) magnesium ion binding (24.4%) glycosyltransferase activity (0.1%)" "IPR000836 (24.9%) IPR004467 (24.9%) IPR023031 (24.9%)" "Phosphoribosyltransferase domain (24.9%) Orotate phosphoribosyl transferase domain (24.9%) Orotate phosphoribosyltransferase (24.9%)" LQTDLEQFDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR003743 (50%) IPR052376 (50%)" "C4-type zinc ribbon domain (50%) Oxidative Scavengers and Glycosyltransferases (50%)" ALVNYTQTSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25%) IPR035376 (25%) IPR038143 (25%)" "NigD-like N-terminal OB domain (25%) NigD-like, C-terminal domain (25%) NigD-like, C-terminal domain superfamily (25%)" LEPTDWYVGMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.7%) IPR015171 (14.7%) IPR019492 (14.7%)" "Glycosyl hydrolase family 13, catalytic domain (14.7%) Cyclomaltodextrinase, N-terminal (14.7%) Cyclo-malto-dextrinase, C-terminal (14.7%)" NPQGYLSYSNVYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (52.4%) IPR011990 (47.6%)" "Tetratricopeptide repeat (52.4%) Tetratricopeptide-like helical domain superfamily (47.6%)" TVMDLVK root "5.4.99.- (90.6%) 3.6.4.13 (1.6%) 2.7.10.2 (1.4%)" "Transferring other groups (90.6%) RNA helicase (1.6%) non-specific protein-tyrosine kinase (1.4%)" "GO:0000455 (22.4%) GO:0006355 (1.1%) GO:0009584 (1.1%)" "GO:0005737 (1.2%) GO:0005829 (1.1%) GO:0005886 (0.7%)" "GO:0003723 (23.6%) GO:0120159 (22.4%) GO:0005524 (1.8%)" "enzyme-directed rRNA pseudouridine synthesis (22.4%) regulation of DNA-templated transcription (1.1%) detection of visible light (1.1%)" "cytoplasm (1.2%) cytosol (1.1%) plasma membrane (0.7%)" "RNA binding (23.6%) rRNA pseudouridine synthase activity (22.4%) ATP binding (1.8%)" "IPR006145 (9.2%) IPR020103 (9.1%) IPR050343 (9.1%)" "Pseudouridine synthase, RsuA/RluA-like (9.2%) Pseudouridine synthase, catalytic domain superfamily (9.1%) Ribosomal RNA Pseudouridine Synthase RsuA (9.1%)" AVVGWNVLTAVVGTDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.4%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.4%) "IPR028994 (20.1%) IPR003284 (14.4%) IPR022045 (13.7%)" "Integrin alpha, N-terminal (20.1%) Salmonella virulence plasmid 65kDa B protein (14.4%) Insecticide toxin TcdB middle/N-terminal (13.7%)" VTTTADKNWFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0019867 (50%) GO:2001070 (50%) outer membrane (50%) starch binding (50%) "IPR033408 (80%) IPR032187 (20%)" "Outer membrane protein SusF, N-terminal domain (80%) Outer membrane protein SusF/SusE-like, C-terminal (20%)" LTQVPRPSGHLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25.1%) GO:0005829 (25.1%) "GO:0070573 (25.1%) GO:0046872 (24.6%)" proteolysis (25.1%) cytosol (25.1%) "metallodipeptidase activity (25.1%) metal ion binding (24.6%)" "IPR001160 (33.3%) IPR002933 (32.7%) IPR011650 (32.7%)" "Peptidase M20C, Xaa-His dipeptidase (33.3%) Peptidase M20 (32.7%) Peptidase M20, dimerisation domain (32.7%)" FGGEEFAK root 3.2.1.21 (100%) beta-glucosidase (100%) "GO:0009251 (43.5%) GO:0005975 (1.6%)" "GO:0005789 (1.6%) GO:0016020 (1.6%)" "GO:0008422 (43.5%) GO:0004497 (1.6%) GO:0004553 (1.6%)" "glucan catabolic process (43.5%) carbohydrate metabolic process (1.6%)" "endoplasmic reticulum membrane (1.6%) membrane (1.6%)" "beta-glucosidase activity (43.5%) monooxygenase activity (1.6%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.6%)" "IPR002772 (12.5%) IPR001764 (12.1%) IPR013783 (12.1%)" "Glycoside hydrolase family 3 C-terminal domain (12.5%) Glycoside hydrolase, family 3, N-terminal (12.1%) Immunoglobulin-like fold (12.1%)" NDLTGSVTALKPDEMSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.1%) IPR039426 (13.1%) IPR000531 (12.4%)" "TonB-dependent receptor, plug domain (13.1%) TonB-dependent receptor-like (13.1%) TonB-dependent receptor-like, beta-barrel (12.4%)" LLQVADYDVAAAER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0051301 (10%) GO:0051603 (10%)" GO:0009376 (10%) "GO:0005524 (10%) GO:0008270 (10%) GO:0016887 (10%)" "cell division (10%) proteolysis involved in protein catabolic process (10%)" HslUV protease complex (10%) "ATP binding (10%) zinc ion binding (10%) ATP hydrolysis activity (10%)" "IPR003593 (11.6%) IPR003959 (11.6%) IPR004487 (11.6%)" "AAA+ ATPase domain (11.6%) ATPase, AAA-type, core (11.6%) Clp protease, ATP-binding subunit ClpX (11.6%)" EENSLSLAATADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.1%) "GO:0005524 (25.1%) GO:0042802 (24.8%) GO:0004713 (20.6%)" plasma membrane (25.1%) "ATP binding (25.1%) identical protein binding (24.8%) protein tyrosine kinase activity (20.6%)" "IPR005702 (17.9%) IPR025669 (17.9%) IPR050445 (17.9%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (17.9%) AAA domain (17.9%) Bacterial polysaccharide biosynthesis and export (17.9%)" LPNKYDSYDALMFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (4.2%) GO:0009279 (91.7%) GO:0015344 (4.2%) siderophore transmembrane transport (4.2%) cell outer membrane (91.7%) siderophore uptake transmembrane transporter activity (4.2%) "IPR012910 (15.9%) IPR023997 (15.9%) IPR039426 (15.9%)" "TonB-dependent receptor, plug domain (15.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15.9%) TonB-dependent receptor-like (15.9%)" KTELVTLK root "5.1.3.3 (96.8%) 5.1.3.- (3.2%)" "aldose 1-epimerase (96.8%) Acting on carbohydrates and derivatives (3.2%)" "GO:0006006 (15.6%) GO:0033499 (15.6%) GO:0006508 (1%)" "GO:0005737 (16.6%) GO:0016020 (1.5%) GO:0005776 (1%)" "GO:0004034 (15.6%) GO:0030246 (14.6%) GO:0004222 (1%)" "glucose metabolic process (15.6%) galactose catabolic process via UDP-galactose, Leloir pathway (15.6%) proteolysis (1%)" "cytoplasm (16.6%) membrane (1.5%) autophagosome (1%)" "aldose 1-epimerase activity (15.6%) carbohydrate binding (14.6%) metalloendopeptidase activity (1%)" "IPR008183 (13.2%) IPR018052 (13.2%) IPR047215 (13.2%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (13.2%) Aldose 1-epimerase, conserved site (13.2%) Galactose mutarotase-like (13.2%)" TVGSGQLTTLLDDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.3%) GO:0032045 (14.3%)" "GO:0000287 (14.3%) GO:0003746 (14.3%) GO:0003924 (14.3%)" "cytosol (14.3%) guanyl-nucleotide exchange factor complex (14.3%)" "magnesium ion binding (14.3%) translation elongation factor activity (14.3%) GTPase activity (14.3%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" MAGVNLTTTEGSPDADVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006826 (20.9%) GO:0044718 (4.7%)" GO:0009279 (67.4%) "GO:0015344 (4.7%) GO:0004180 (2.3%)" "iron ion transport (20.9%) siderophore transmembrane transport (4.7%)" cell outer membrane (67.4%) "siderophore uptake transmembrane transporter activity (4.7%) carboxypeptidase activity (2.3%)" "IPR012910 (15.1%) IPR037066 (15.1%) IPR039426 (15.1%)" "TonB-dependent receptor, plug domain (15.1%) TonB-dependent receptor, plug domain superfamily (15.1%) TonB-dependent receptor-like (15.1%)" VLVVQGPNTNLDNTVAHNYMAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030245 (25%) "GO:0005576 (25%) GO:0009986 (25%)" GO:0008422 (25%) cellulose catabolic process (25%) "extracellular region (25%) cell surface (25%)" beta-glucosidase activity (25%) "IPR001547 (20%) IPR013783 (20%) IPR017853 (20%)" "Glycoside hydrolase, family 5 (20%) Immunoglobulin-like fold (20%) Glycoside hydrolase superfamily (20%)" YFVGESLYQNAPEPR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR017689 (34.1%) IPR039565 (34.1%) IPR011990 (31.7%)" "Outer membrane protein assembly factor BamD (34.1%) Outer membrane lipoprotein BamD-like (34.1%) Tetratricopeptide-like helical domain superfamily (31.7%)" FALDLVR root "2.5.1.15 (22.5%) 1.3.5.1 (13.1%) 5.6.2.4 (10%)" "dihydropteroate synthase (22.5%) succinate dehydrogenase (13.1%) DNA 3'-5' helicase (10%)" "GO:0046656 (1.7%) GO:0046654 (1.6%) GO:0006099 (1%)" "GO:0016020 (8.3%) GO:0005829 (4.1%) GO:0005730 (2.9%)" "GO:0005524 (7.6%) GO:0140359 (6.1%) GO:0016887 (4.6%)" "folic acid biosynthetic process (1.7%) tetrahydrofolate biosynthetic process (1.6%) tricarboxylic acid cycle (1%)" "membrane (8.3%) cytosol (4.1%) nucleolus (2.9%)" "ATP binding (7.6%) ABC-type transporter activity (6.1%) ATP hydrolysis activity (4.6%)" "IPR027417 (4.7%) IPR013525 (4%) IPR003593 (3.6%)" "P-loop containing nucleoside triphosphate hydrolase (4.7%) ABC-2 type transporter, transmembrane domain (4%) AAA+ ATPase domain (3.6%)" WATFPSVSGAYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GQWATSLQYHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.6%) "GO:0004553 (33.6%) GO:0030246 (32.8%)" carbohydrate metabolic process (33.6%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.6%) carbohydrate binding (32.8%)" "IPR006710 (12.9%) IPR051795 (12.9%) IPR005084 (12.6%)" "Glycoside hydrolase, family 43 (12.9%) Glycosyl Hydrolase Family 43 (12.9%) Carbohydrate binding module family 6 (12.6%)" LLEMLYPDEEKLTYSYNLGGQLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.7%) GO:0005737 (48.7%)" GO:0016787 (2.6%) "extracellular region (48.7%) cytoplasm (48.7%)" hydrolase activity (2.6%) "IPR050708 (17.4%) IPR006530 (16.4%) IPR031325 (16.4%)" "Type VI secretion system VgrG/RHS (17.4%) YD repeat (16.4%) RHS repeat (16.4%)" ELSNGKVDEVANNWFLGEPLNVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" AFPKEADELFSQAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.8%) GO:0022900 (14.1%) GO:0044281 (13.7%)" "GO:0030976 (14.5%) GO:0005506 (14.1%) GO:0051539 (14.1%)" "response to oxidative stress (14.8%) electron transport chain (14.1%) small molecule metabolic process (13.7%)" "thiamine pyrophosphate binding (14.5%) iron ion binding (14.1%) 4 iron, 4 sulfur cluster binding (14.1%)" "IPR029061 (8.1%) IPR050722 (8.1%) IPR011766 (7.9%)" "Thiamin diphosphate-binding fold (8.1%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%)" DYNWMMAFTEK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004824 (16.7%) GO:0005524 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) lysine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002313 (12.7%) IPR004364 (12.7%) IPR006195 (12.7%)" "Lysine-tRNA ligase, class II (12.7%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.7%) Aminoacyl-tRNA synthetase, class II (12.7%)" RLPQLPLLCDPSHLGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.5 (100%) chorismate mutase (100%) GO:0046417 (50%) GO:0004106 (50%) chorismate metabolic process (50%) chorismate mutase activity (50%) "IPR002701 (17.9%) IPR006218 (17.9%) IPR052899 (17.9%)" "Chorismate mutase II, prokaryotic-type (17.9%) DAHP synthetase I/KDSA (17.9%) Class-I DAHP synthase (17.9%)" DLGLQFQGDFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (50%) GO:0015288 (50%) membrane (50%) porin activity (50%) "IPR010870 (50%) IPR023614 (48.7%) IPR033900 (1.3%)" "Phosphate-selective porin O/P (50%) Porin domain superfamily (48.7%) Porin domain, Gram-negative type (1.3%)" SELQMNLK root "GO:0006412 (16.6%) GO:0006508 (0.2%)" "GO:0005829 (16.6%) GO:0015935 (16.6%)" "GO:0003735 (16.6%) GO:0019843 (16.6%) GO:0000049 (16.4%)" "translation (16.6%) proteolysis (0.2%)" "cytosol (16.6%) small ribosomal subunit (16.6%)" "structural constituent of ribosome (16.6%) rRNA binding (16.6%) tRNA binding (16.4%)" "IPR001892 (19.8%) IPR010979 (19.8%) IPR018269 (19.8%)" "Small ribosomal subunit protein uS13 (19.8%) Small ribosomal subunit protein uS13-like, H2TH (19.8%) Small ribosomal subunit protein uS13, conserved site (19.8%)" VVVSGTLLDYNGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) YDLTVPFAR root "6.1.1.21 (98%) 4.3.1.24 (1%) 2.7.11.1 (0.7%)" "histidine--tRNA ligase (98%) phenylalanine ammonia-lyase (1%) non-specific serine/threonine protein kinase (0.7%)" "GO:0006427 (15.4%) GO:0032543 (10.2%) GO:0002119 (0.3%)" "GO:0005829 (11%) GO:0005739 (10.9%) GO:0005737 (4.5%)" "GO:0004821 (15.4%) GO:0005524 (15%) GO:0003723 (10.6%)" "histidyl-tRNA aminoacylation (15.4%) mitochondrial translation (10.2%) nematode larval development (0.3%)" "cytosol (11%) mitochondrion (10.9%) cytoplasm (4.5%)" "histidine-tRNA ligase activity (15.4%) ATP binding (15%) RNA binding (10.6%)" "IPR041715 (12.9%) IPR045864 (12.9%) IPR036621 (12.3%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (12.9%) Anticodon-binding domain superfamily (12.3%)" MELDDYLFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) HLVNHVAESGVDEQSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.3.5.1 (100%) NAD(+) synthase (glutamine-hydrolyzing) (100%) GO:0009435 (16.8%) GO:0005737 (16.8%) "GO:0003952 (16.8%) GO:0004359 (16.8%) GO:0005524 (16.3%)" NAD+ biosynthetic process (16.8%) cytoplasm (16.8%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.8%) glutaminase activity (16.8%) ATP binding (16.3%)" "IPR003694 (15.2%) IPR022310 (15.2%) IPR003010 (14.7%)" "NAD(+) synthetase (15.2%) NAD/GMP synthase (15.2%) Carbon-nitrogen hydrolase (14.7%)" MLSEADPNYKESADLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.11.1.- (66.7%) 1.-.-.- (33.3%)" "Peroxidases (66.7%) Oxidoreductases (33.3%)" GO:0034599 (50%) GO:0004601 (50%) cellular response to oxidative stress (50%) peroxidase activity (50%) "IPR000889 (34.3%) IPR036249 (34.3%) IPR029760 (31.4%)" "Glutathione peroxidase (34.3%) Thioredoxin-like superfamily (34.3%) Glutathione peroxidase conserved site (31.4%)" YVEQLASAGK root GO:0005975 (37.5%) GO:0009341 (12.5%) "GO:0004565 (37.5%) GO:0016787 (12.5%)" carbohydrate metabolic process (37.5%) beta-galactosidase complex (12.5%) "beta-galactosidase activity (37.5%) hydrolase activity (12.5%)" "IPR040719 (32.9%) IPR031330 (31.6%) IPR017853 (30.4%)" "Domain of unknown function DUF5597 (32.9%) Glycoside hydrolase 35, catalytic domain (31.6%) Glycoside hydrolase superfamily (30.4%)" TELTLNDLLNER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" HLFVDQSPLYNADK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (34.5%) IPR011042 (32.8%) IPR029058 (32.8%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.5%) Six-bladed beta-propeller, TolB-like (32.8%) Alpha/Beta hydrolase fold (32.8%)" NPVLDADYSDPDVCR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.4%) IPR041542 (20.4%) IPR051795 (20.4%)" "Glycoside hydrolase, family 43 (20.4%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.4%) Glycosyl Hydrolase Family 43 (20.4%)" GMVSFDYDSYYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" VSQAQSLLPAEVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009636 (25%) GO:0005886 (25%) "GO:0015562 (25%) GO:0042910 (25%)" response to toxic substance (25%) plasma membrane (25%) "efflux transmembrane transporter activity (25%) xenobiotic transmembrane transporter activity (25%)" "IPR001036 (33.3%) IPR004764 (33.3%) IPR027463 (33.3%)" "Acriflavin resistance protein (33.3%) Multidrug resistance protein MdtF-like (33.3%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%)" MQQGQENLPEEQMNQVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) "GO:0003755 (48.4%) GO:0016853 (1.6%)" plasma membrane (50%) "peptidyl-prolyl cis-trans isomerase activity (48.4%) isomerase activity (1.6%)" "IPR052029 (27.7%) IPR027304 (25.9%) IPR046357 (25.9%)" "Periplasmic chaperone PpiD (27.7%) Trigger factor/SurA domain superfamily (25.9%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.9%)" VNDAMSLLTDKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0003700 (50%) GO:0043565 (50%)" "DNA-binding transcription factor activity (50%) sequence-specific DNA binding (50%)" "IPR018060 (50%) IPR009057 (43.3%) IPR020449 (6.7%)" "AraC-like, DNA binding HTH domain (50%) Homedomain-like superfamily (43.3%) Transcription regulator HTH, AraC- type, HTH domain (6.7%)" LVADLLSVAGLDR Pseudomonadati Bacteria Pseudomonadati 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (11.1%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (11.1%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (19.3%) IPR005946 (19.3%) IPR029057 (19.3%)" "Phosphoribosyltransferase domain (19.3%) Ribose-phosphate pyrophosphokinase (19.3%) Phosphoribosyltransferase-like (19.3%)" RGELALTYLYGLGR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (16.8%) "GO:0005829 (16.7%) GO:0015935 (16.7%) GO:0005840 (0.1%)" "GO:0003735 (16.8%) GO:0019843 (16.7%) GO:0000049 (16%)" translation (16.8%) "cytosol (16.7%) small ribosomal subunit (16.7%) ribosome (0.1%)" "structural constituent of ribosome (16.8%) rRNA binding (16.7%) tRNA binding (16%)" "IPR001892 (20.1%) IPR010979 (20%) IPR018269 (20%)" "Small ribosomal subunit protein uS13 (20.1%) Small ribosomal subunit protein uS13-like, H2TH (20%) Small ribosomal subunit protein uS13, conserved site (20%)" GMVVVHPGALTPHDHFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.6%) GO:0032045 (13.7%)" "GO:0003746 (14.6%) GO:0005525 (14.6%) GO:0003924 (14%)" "cytosol (14.6%) guanyl-nucleotide exchange factor complex (13.7%)" "translation elongation factor activity (14.6%) GTP binding (14.6%) GTPase activity (14%)" "IPR004160 (8.5%) IPR004161 (8.5%) IPR009000 (8.5%)" "Translation elongation factor EFTu/EF1A, C-terminal (8.5%) Translation elongation factor EFTu-like, domain 2 (8.5%) Translation protein, beta-barrel domain superfamily (8.5%)" LLRPLPQAALDANDQLTLADQNPGY Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.5%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.5%)" LATLLPSGK root 3.2.1.52 (100%) beta-N-acetylhexosaminidase (100%) "GO:0005975 (23.1%) GO:0030203 (23.1%) GO:0045944 (0.9%)" "GO:0016020 (23.9%) GO:0005634 (0.9%) GO:0005789 (0.9%)" "GO:0004563 (23.1%) GO:0000977 (0.9%) GO:0003682 (0.9%)" "carbohydrate metabolic process (23.1%) glycosaminoglycan metabolic process (23.1%) positive regulation of transcription by RNA polymerase II (0.9%)" "membrane (23.9%) nucleus (0.9%) endoplasmic reticulum membrane (0.9%)" "beta-N-acetylhexosaminidase activity (23.1%) RNA polymerase II transcription regulatory region sequence-specific DNA binding (0.9%) chromatin binding (0.9%)" "IPR015883 (14.4%) IPR025705 (14.4%) IPR011658 (13.8%)" "Glycoside hydrolase family 20, catalytic domain (14.4%) Beta-hexosaminidase (14.4%) PA14 domain (13.8%)" GLLPNDMESLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.5%) IPR032466 (47.5%)" "Uronate isomerase (52.5%) Metal-dependent hydrolase (47.5%)" HGLNLTSLSQVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015744 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) succinate transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) "IPR010619 (33.3%) IPR024528 (33.3%) IPR050539 (33.3%)" "Threonine/serine exporter-like, N-terminal domain (33.3%) Threonine/Serine exporter, ThrE (33.3%) ThrE Dicarboxylate/Amino Acid Exporter (33.3%)" GGYDMGLVVDPDVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "5.4.2.10 (96%) 5.4.2.2 (4%)" "phosphoglucosamine mutase (96%) phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (4%)" "GO:0005975 (14.3%) GO:0006048 (14.3%) GO:0009252 (14.3%)" GO:0005829 (14.3%) "GO:0000287 (14.3%) GO:0004615 (14.3%) GO:0008966 (14.3%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.3%) peptidoglycan biosynthetic process (14.3%)" cytosol (14.3%) "magnesium ion binding (14.3%) phosphomannomutase activity (14.3%) phosphoglucosamine mutase activity (14.3%)" "IPR005841 (10%) IPR005843 (10%) IPR005844 (10%)" "Alpha-D-phosphohexomutase superfamily (10%) Alpha-D-phosphohexomutase, C-terminal (10%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (10%)" VGELQFPDALLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (16.4%) GO:0043335 (15.8%) GO:0051083 (15.8%)" GO:0005737 (3.6%) "GO:0003755 (15.8%) GO:0043022 (15.8%) GO:0044183 (15.8%)" "protein transport (16.4%) protein unfolding (15.8%) 'de novo' cotranslational protein folding (15.8%)" cytoplasm (3.6%) "peptidyl-prolyl cis-trans isomerase activity (15.8%) ribosome binding (15.8%) protein folding chaperone (15.8%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR037041 (19.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor, C-terminal domain superfamily (19.4%)" QSFGLDPER Bacteria Bacteria 2.7.4.22 (100%) UMP kinase (100%) "GO:0006225 (20.4%) GO:0044210 (18.3%) GO:0032259 (1.1%)" GO:0005737 (18.3%) "GO:0005524 (20.4%) GO:0033862 (20.4%) GO:0008168 (1.1%)" "UDP biosynthetic process (20.4%) 'de novo' CTP biosynthetic process (18.3%) methylation (1.1%)" cytoplasm (18.3%) "ATP binding (20.4%) UMP kinase activity (20.4%) methyltransferase activity (1.1%)" "IPR001048 (26.4%) IPR036393 (25%) IPR015963 (23.6%)" "Aspartate/glutamate/uridylate kinase (26.4%) Acetylglutamate kinase-like superfamily (25%) Uridylate kinase, bacteria (23.6%)" AVTWPTLCALTR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.5%) GO:0005737 (19.3%) "GO:0003852 (20.5%) GO:0003985 (19.3%) GO:0030145 (19.3%)" L-leucine biosynthetic process (20.5%) cytoplasm (19.3%) "2-isopropylmalate synthase activity (20.5%) acetyl-CoA C-acetyltransferase activity (19.3%) manganese ion binding (19.3%)" "IPR000891 (12.6%) IPR002034 (12.6%) IPR013785 (12.6%)" "Pyruvate carboxyltransferase (12.6%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.6%) Aldolase-type TIM barrel (12.6%)" TSANPFAMQALADSLQGVDVPVLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.99.5 (100%) chorismate mutase (100%) GO:0046417 (50%) GO:0004106 (50%) chorismate metabolic process (50%) chorismate mutase activity (50%) "IPR006218 (19.2%) IPR052899 (19.2%) IPR002701 (17.9%)" "DAHP synthetase I/KDSA (19.2%) Class-I DAHP synthase (19.2%) Chorismate mutase II, prokaryotic-type (17.9%)" HGDLLLPCR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR025669 (33.3%) IPR027417 (33.3%) IPR050678 (33.3%)" "AAA domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%) DNA Partitioning ATPase (33.3%)" AGSMQEGQYASVGVANR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) VFRPADADETTVCWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.2.1.1 (94.7%) 2.2.1.- (5.3%)" "transketolase (94.7%) Transketolases and transaldolases (5.3%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (25%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (25%)" "IPR005475 (12.8%) IPR009014 (12.8%) IPR020826 (12.8%)" "Transketolase-like, pyrimidine-binding domain (12.8%) Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II (12.8%) Transketolase binding site (12.8%)" VRGEEALLSTDDSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (17.4%) GO:0006085 (15.9%)" GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0008776 (17.4%) GO:0000287 (15.9%)" "acetate metabolic process (17.4%) acetyl-CoA biosynthetic process (15.9%)" cytoplasm (15.9%) "ATP binding (17.4%) acetate kinase activity (17.4%) magnesium ion binding (15.9%)" "IPR000890 (25.3%) IPR004372 (25.3%) IPR023865 (25.3%)" "Aliphatic acid kinase, short-chain (25.3%) Acetate/propionate kinase (25.3%) Aliphatic acid kinase, short-chain, conserved site (25.3%)" FNLFSLK root "7.2.1.1 (45.6%) 2.3.1.1 (7.8%) 2.3.1.35 (7.8%)" "NADH:ubiquinone reductase (Na(+)-transporting) (45.6%) amino-acid N-acetyltransferase (7.8%) glutamate N-acetyltransferase (7.8%)" "GO:0006814 (5.2%) GO:0006520 (1.4%) GO:0006508 (1.1%)" "GO:0005886 (9.1%) GO:0016020 (6.5%) GO:0005737 (2.4%)" "GO:0046872 (5.8%) GO:0009055 (5.2%) GO:0016655 (5.2%)" "sodium ion transport (5.2%) amino acid metabolic process (1.4%) proteolysis (1.1%)" "plasma membrane (9.1%) membrane (6.5%) cytoplasm (2.4%)" "metal ion binding (5.8%) electron transfer activity (5.2%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (5.2%)" "IPR001041 (3.1%) IPR001433 (3.1%) IPR008333 (3.1%)" "2Fe-2S ferredoxin-type iron-sulfur binding domain (3.1%) Oxidoreductase FAD/NAD(P)-binding (3.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (3.1%)" VDVQRPCDVVEDLLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005147 (7.8%) IPR045060 (7.8%) IPR005121 (7.8%)" "tRNA synthetase, B5-domain (7.8%) Phenylalanine-tRNA ligase, class IIc, beta subunit (7.8%) Ferrodoxin-fold anticodon-binding domain (7.8%)" DNPELLDELEAK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006281 (12.5%) GO:0006310 (12.5%) GO:0009432 (12.5%)" GO:0005829 (12.5%) "GO:0003684 (12.5%) GO:0003697 (12.5%) GO:0005524 (12.5%)" "DNA repair (12.5%) DNA recombination (12.5%) SOS response (12.5%)" cytosol (12.5%) "damaged DNA binding (12.5%) single-stranded DNA binding (12.5%) ATP binding (12.5%)" "IPR003593 (11.2%) IPR013765 (11.2%) IPR020587 (11.2%)" "AAA+ ATPase domain (11.2%) DNA recombination and repair protein RecA (11.2%) DNA recombination and repair protein RecA, monomer-monomer interface (11.2%)" DNLGDFSYSVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" GPGETQLEMDRR root 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0005737 (20%) "GO:0005525 (20%) GO:0043022 (20%) GO:0046872 (20%)" cytoplasm (20%) "GTP binding (20%) ribosome binding (20%) metal ion binding (20%)" "IPR006073 (13.1%) IPR016496 (13.1%) IPR030394 (13.1%)" "GTP binding domain (13.1%) GTPase HflX (13.1%) HflX-type guanine nucleotide-binding (G) domain (13.1%)" FASNTQLLQVSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0043165 (50%) GO:0019867 (50%) Gram-negative-bacterium-type cell outer membrane assembly (50%) outer membrane (50%) IPR007485 (100%) LPS-assembly lipoprotein LptE (100%) TFMNMLK root "2.3.1.54 (93.9%) 2.7.7.7 (3%) 2.7.8.31 (3%)" "formate C-acetyltransferase (93.9%) DNA-directed DNA polymerase (3%) undecaprenyl-phosphate glucose phosphotransferase (3%)" "GO:0006006 (22.7%) GO:0006004 (2.3%) GO:0006261 (0.8%)" "GO:0005829 (22.7%) GO:0034702 (4.7%) GO:0016020 (3.1%)" "GO:0008861 (22.7%) GO:0005249 (4.7%) GO:0016757 (2.3%)" "glucose metabolic process (22.7%) fucose metabolic process (2.3%) DNA-templated DNA replication (0.8%)" "cytosol (22.7%) monoatomic ion channel complex (4.7%) membrane (3.1%)" "formate C-acetyltransferase activity (22.7%) voltage-gated potassium channel activity (4.7%) glycosyltransferase activity (2.3%)" "IPR001150 (11.9%) IPR004184 (11.9%) IPR005949 (11.9%)" "Glycine radical domain (11.9%) Pyruvate formate lyase domain (11.9%) Formate acetyltransferase (11.9%)" FQGAPLQPDALGTLFSGSAVVDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.7%) IPR013148 (14.7%) IPR013189 (14.7%)" "Glycoside hydrolase, family 32 (14.7%) Glycosyl hydrolase family 32, N-terminal (14.7%) Glycosyl hydrolase family 32, C-terminal (14.7%)" YYECELDGQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (25%) GO:0005886 (25%) "GO:0010181 (25%) GO:0016655 (25%)" sodium ion transport (25%) plasma membrane (25%) "FMN binding (25%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (25%)" "IPR007329 (50%) IPR010204 (50%)" "FMN-binding (50%) Na(+)-translocating NADH-quinone reductase subunit C (50%)" VVALANEDQTLYGVGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LDGWMVKPVDFDASK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" ADSDFDTLLYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.4 (100%) asparagine synthase (glutamine-hydrolyzing) (100%) GO:0006529 (25%) GO:0005829 (25%) "GO:0004066 (25%) GO:0005524 (25%)" obsolete asparagine biosynthetic process (25%) cytosol (25%) "asparagine synthase (glutamine-hydrolyzing) activity (25%) ATP binding (25%)" "IPR001962 (14.6%) IPR006426 (14.6%) IPR017932 (14.6%)" "Asparagine synthase (14.6%) Asparagine synthase, glutamine-hydrolyzing (14.6%) Glutamine amidotransferase type 2 domain (14.6%)" SPGYFSGLLDPQTSEASELYSADGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.4.1.- (50%) 3.4.-.- (50%)" "Hexosyltransferases (50%) Acting on peptide bonds (peptidases) (50%)" "GO:0008360 (11.4%) GO:0009252 (11.4%) GO:0071555 (11.4%)" "GO:0030288 (11.4%) GO:0005886 (10.2%) GO:0016020 (1.2%)" "GO:0008658 (11.4%) GO:0008955 (11.4%) GO:0004180 (10.2%)" "regulation of cell shape (11.4%) peptidoglycan biosynthetic process (11.4%) cell wall organization (11.4%)" "outer membrane-bounded periplasmic space (11.4%) plasma membrane (10.2%) membrane (1.2%)" "penicillin binding (11.4%) peptidoglycan glycosyltransferase activity (11.4%) carboxypeptidase activity (10.2%)" "IPR001264 (17.6%) IPR001460 (17.6%) IPR050396 (17.6%)" "Glycosyl transferase, family 51 (17.6%) Penicillin-binding protein, transpeptidase (17.6%) Glycosyltransferase 51/Transpeptidase (17.6%)" SLVVVVNK root 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) "GO:0042254 (29.8%) GO:0006412 (0.4%) GO:0000028 (0.2%)" "GO:0005737 (0.7%) GO:0005829 (0.4%) GO:0016020 (0.4%)" "GO:0005525 (31.4%) GO:0043022 (29.6%) GO:0016787 (2.6%)" "ribosome biogenesis (29.8%) translation (0.4%) ribosomal small subunit assembly (0.2%)" "cytoplasm (0.7%) cytosol (0.4%) membrane (0.4%)" "GTP binding (31.4%) ribosome binding (29.6%) hydrolase activity (2.6%)" "IPR027417 (14.2%) IPR005225 (13.8%) IPR006073 (13.8%)" "P-loop containing nucleoside triphosphate hydrolase (14.2%) Small GTP-binding domain (13.8%) GTP binding domain (13.8%)" ELGLLFQDFQLLHDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006865 (3.9%) GO:0051301 (2.6%)" GO:0005886 (22.1%) "GO:0005524 (26%) GO:0016887 (24.7%) GO:0022857 (20.8%)" "amino acid transport (3.9%) cell division (2.6%)" plasma membrane (22.1%) "ATP binding (26%) ATP hydrolysis activity (24.7%) transmembrane transporter activity (20.8%)" "IPR003439 (20.4%) IPR027417 (20.4%) IPR003593 (19.4%)" "ABC transporter-like, ATP-binding domain (20.4%) P-loop containing nucleoside triphosphate hydrolase (20.4%) AAA+ ATPase domain (19.4%)" AEVEKLPAQDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri FDGTEEVLQLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR025366 (100%) Protein of unknown function DUF4270 (100%) TLNESVLQHLDLVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.7%) GO:0030259 (12.7%) GO:0008360 (12.1%)" GO:0005886 (12.1%) "GO:0050511 (12.1%) GO:0051991 (1.2%) GO:0016758 (0.6%)" "carbohydrate metabolic process (12.7%) obsolete lipid glycosylation (12.7%) regulation of cell shape (12.1%)" plasma membrane (12.1%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.1%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (1.2%) hexosyltransferase activity (0.6%)" "IPR004276 (34.4%) IPR006009 (32.8%) IPR007235 (32.8%)" "Glycosyltransferase family 28, N-terminal domain (34.4%) N-acetylglucosaminyltransferase, MurG (32.8%) Glycosyl transferase, family 28, C-terminal (32.8%)" LEVEANAFSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25.3%) GO:0022625 (25.3%) "GO:0003735 (25.3%) GO:0019843 (24%)" translation (25.3%) cytosolic large ribosomal subunit (25.3%) "structural constituent of ribosome (25.3%) rRNA binding (24%)" "IPR001196 (20.2%) IPR005749 (20.2%) IPR021131 (20.2%)" "Large ribosomal subunit protein uL15, conserved site (20.2%) Large ribosomal subunit protein uL15, bacteria (20.2%) Large ribosomal subunit protein uL15/eL18 (20.2%)" FKAGAELADALNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030261 (15.4%) GO:0006270 (7.7%) GO:0006351 (7.7%)" "GO:0005829 (15.4%) GO:1990103 (7.7%) GO:1990178 (7.7%)" "GO:0003677 (15.4%) GO:0030527 (15.4%) GO:0042802 (7.7%)" "chromosome condensation (15.4%) DNA replication initiation (7.7%) DNA-templated transcription (7.7%)" "cytosol (15.4%) DnaA-HU complex (7.7%) HU-DNA complex (7.7%)" "DNA binding (15.4%) structural constituent of chromatin (15.4%) identical protein binding (7.7%)" "IPR000119 (33.3%) IPR010992 (33.3%) IPR020816 (33.3%)" "Histone-like DNA-binding protein (33.3%) Integration host factor (IHF)-like DNA-binding domain superfamily (33.3%) Histone-like DNA-binding protein, conserved site (33.3%)" ELEKPFLDFATER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20%) GO:0008615 (20%)" GO:0005737 (20%) "GO:0004648 (20%) GO:0030170 (20%)" "L-serine biosynthetic process (20%) pyridoxine biosynthetic process (20%)" cytoplasm (20%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20%) pyridoxal phosphate binding (20%)" "IPR000192 (19.5%) IPR022278 (19.5%) IPR015421 (18.8%)" "Aminotransferase class V domain (19.5%) Phosphoserine aminotransferase (19.5%) Pyridoxal phosphate-dependent transferase, major domain (18.8%)" AFLLKPLVTEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20.1%) "GO:0005840 (20.1%) GO:1990904 (20.1%)" "GO:0003735 (20.1%) GO:0019843 (19.6%)" translation (20.1%) "ribosome (20.1%) ribonucleoprotein complex (20.1%)" "structural constituent of ribosome (20.1%) rRNA binding (19.6%)" "IPR012677 (33.3%) IPR012678 (33.3%) IPR013025 (33.3%)" "Nucleotide-binding alpha-beta plait domain superfamily (33.3%) Ribosomal protein uL23/eL15/eS24 core domain superfamily (33.3%) Large ribosomal subunit protein uL23-like (33.3%)" VSEYCYTEQQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.2%) GO:0032259 (0.2%)" "GO:0005737 (12.4%) GO:0005694 (12.2%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0046872 (12.4%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.2%) methylation (0.2%)" "cytoplasm (12.4%) chromosome (12.2%)" "DNA binding (12.6%) ATP binding (12.6%) metal ion binding (12.4%)" "IPR001241 (7.8%) IPR006171 (7.8%) IPR018522 (7.8%)" "DNA topoisomerase, type IIA (7.8%) TOPRIM domain (7.8%) DNA topoisomerase, type IIA, conserved site (7.8%)" VLNLVNNNDFFGAKEEFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" DLSFLDAYPLESLTVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" MTLAEFKENYPNLPLEALANAEGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" QFMDENFLLDTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.4%) IPR032466 (47.6%)" "Uronate isomerase (52.4%) Metal-dependent hydrolase (47.6%)" LGDFDSYGSDPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.7%) GO:0005737 (48.7%)" GO:0016787 (2.6%) "extracellular region (48.7%) cytoplasm (48.7%)" hydrolase activity (2.6%) "IPR022385 (17.1%) IPR050708 (17.1%) IPR006530 (15.2%)" "Rhs repeat-associated core (17.1%) Type VI secretion system VgrG/RHS (17.1%) YD repeat (15.2%)" SGDDAVFDKELTFEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (24.7%) "GO:0046872 (24.7%) GO:0051539 (24.7%) GO:0003861 (23.4%)" L-leucine biosynthetic process (24.7%) "metal ion binding (24.7%) 4 iron, 4 sulfur cluster binding (24.7%) 3-isopropylmalate dehydratase activity (23.4%)" "IPR001030 (14.6%) IPR015931 (14.6%) IPR036008 (14.6%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (14.6%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (14.6%) Aconitase, iron-sulfur domain (14.6%)" KAGVECEVSLENK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044205 (16.7%) "GO:0009055 (16.7%) GO:0016491 (16.7%) GO:0046872 (16.7%)" 'de novo' UMP biosynthetic process (16.7%) "electron transfer activity (16.7%) oxidoreductase activity (16.7%) metal ion binding (16.7%)" "IPR019480 (11.2%) IPR037117 (11.2%) IPR039261 (11.2%)" "Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.2%) Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily (11.2%) Ferredoxin-NADP reductase (FNR), nucleotide-binding domain (11.2%)" GLNGYAQSFVNAVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (22.8%) GO:0006080 (21.7%) GO:0030245 (6.5%)" "GO:0005576 (8.7%) GO:0009986 (6.5%)" "GO:0016985 (21.7%) GO:0008422 (8.7%) GO:0004553 (1.1%)" "polysaccharide catabolic process (22.8%) substituted mannan metabolic process (21.7%) cellulose catabolic process (6.5%)" "extracellular region (8.7%) cell surface (6.5%)" "mannan endo-1,4-beta-mannosidase activity (21.7%) beta-glucosidase activity (8.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.1%)" "IPR001547 (26.4%) IPR017853 (24.5%) IPR022790 (23.6%)" "Glycoside hydrolase, family 5 (26.4%) Glycoside hydrolase superfamily (24.5%) Glycosyl hydrolase family 26 domain (23.6%)" LQTYYGGVNAEPLVGATPTGYYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (35.5%) IPR012944 (35.5%) IPR033985 (29%)" "Tetratricopeptide-like helical domain superfamily (35.5%) RagB/SusD domain (35.5%) SusD-like, N-terminal (29%)" ASAFVPLR root "3.1.-.- (33.3%) 3.4.21.107 (33.3%) 4.2.1.134 (33.3%)" "Acting on ester bonds (33.3%) peptidase Do (33.3%) very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase (33.3%)" "GO:0006357 (8.5%) GO:0006351 (1.8%) GO:0040034 (1.2%)" "GO:0005737 (23.2%) GO:0005576 (22.6%) GO:0016592 (8.5%)" "GO:0003712 (8.5%) GO:0003677 (1.8%) GO:0008270 (1.8%)" "regulation of transcription by RNA polymerase II (8.5%) DNA-templated transcription (1.8%) regulation of development, heterochronic (1.2%)" "cytoplasm (23.2%) extracellular region (22.6%) mediator complex (8.5%)" "transcription coregulator activity (8.5%) DNA binding (1.8%) zinc ion binding (1.8%)" "IPR022045 (12.5%) IPR006530 (11.5%) IPR050708 (11.5%)" "Insecticide toxin TcdB middle/N-terminal (12.5%) YD repeat (11.5%) Type VI secretion system VgrG/RHS (11.5%)" AEAGTSAATVYVER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009418 (100%) pilus shaft (100%) "IPR029140 (50%) IPR047786 (50%)" "Minor fimbrium subunit Mfa1, C-terminal (50%) Fimbria major subunit Mfa1 (50%)" YMELTSELMDEYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.6%) GO:0006002 (13.8%)" GO:0005829 (14.6%) "GO:0003872 (14.6%) GO:0046872 (14.6%) GO:0005524 (13.8%)" "response to glucose (14.6%) fructose 6-phosphate metabolic process (13.8%)" cytosol (14.6%) "6-phosphofructokinase activity (14.6%) metal ion binding (14.6%) ATP binding (13.8%)" "IPR000023 (26.1%) IPR011183 (24.6%) IPR022953 (24.6%)" "Phosphofructokinase domain (26.1%) Pyrophosphate-dependent phosphofructokinase PfpB (24.6%) ATP-dependent 6-phosphofructokinase (24.6%)" SVETLMDTVDEWLQEPER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (16.1%) GO:0032045 (12.9%)" "GO:0003746 (16.1%) GO:0005525 (16.1%) GO:0000287 (12.9%)" "cytosol (16.1%) guanyl-nucleotide exchange factor complex (12.9%)" "translation elongation factor activity (16.1%) GTP binding (16.1%) magnesium ion binding (12.9%)" "IPR004160 (9.1%) IPR004161 (9.1%) IPR009000 (9.1%)" "Translation elongation factor EFTu/EF1A, C-terminal (9.1%) Translation elongation factor EFTu-like, domain 2 (9.1%) Translation protein, beta-barrel domain superfamily (9.1%)" LEELNFEGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.1 (100%) citrate (Si)-synthase (100%) "GO:0005975 (25%) GO:0006099 (25%)" GO:0005829 (25%) "GO:0036440 (16.7%) GO:0046912 (8.3%)" "carbohydrate metabolic process (25%) tricarboxylic acid cycle (25%)" cytosol (25%) "citrate synthase activity (16.7%) acyltransferase activity, acyl groups converted into alkyl on transfer (8.3%)" "IPR002020 (20.7%) IPR016142 (20.1%) IPR036969 (20.1%)" "Citrate synthase (20.7%) Citrate synthase-like, large alpha subdomain (20.1%) Citrate synthase superfamily (20.1%)" KGEALEGLVLTLAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.3%) IPR009027 (14.3%) IPR020069 (14.3%)" "Large ribosomal subunit protein bL9 (14.3%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.3%) Large ribosomal subunit protein bL9, C-terminal (14.3%)" HELGQLAVNGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.92 (100%) 5-dehydro-2-deoxygluconokinase (100%) "GO:0016301 (94.7%) GO:0047590 (5.3%)" "kinase activity (94.7%) 5-dehydro-2-deoxygluconokinase activity (5.3%)" "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" METYAEELASAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (9.7%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (9.7%)" "IPR004463 (14.7%) IPR010084 (14.7%) IPR013114 (14.7%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.7%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.7%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.7%)" YSDGSGCGNETASEKPLMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.41 (100%) pullulanase (100%) GO:0005975 (53.8%) "GO:0016798 (30.8%) GO:0051060 (15.4%)" carbohydrate metabolic process (53.8%) "hydrolase activity, acting on glycosyl bonds (30.8%) pullulanase activity (15.4%)" "IPR006047 (14.9%) IPR011840 (14.6%) IPR049117 (14.6%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Pullulanase, type I (14.6%) Pullulanase, all-beta domain (14.6%)" YVEDVEFYAEDAGR Bacteria Bacteria 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (32.5%) GO:0005737 (11.6%) "GO:0003852 (32.5%) GO:0003985 (11.6%) GO:0030145 (11.6%)" L-leucine biosynthetic process (32.5%) cytoplasm (11.6%) "2-isopropylmalate synthase activity (32.5%) acetyl-CoA C-acetyltransferase activity (11.6%) manganese ion binding (11.6%)" "IPR000891 (16.4%) IPR002034 (16.4%) IPR013785 (16.4%)" "Pyruvate carboxyltransferase (16.4%) Alpha-isopropylmalate/homocitrate synthase, conserved site (16.4%) Aldolase-type TIM barrel (16.4%)" LSTDLPEFAEAEAGVQKELDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (17.9%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (17.9%)" "IPR003953 (14.3%) IPR011280 (14.3%) IPR015939 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.3%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.3%)" VVVTGLGAVTPVGNTPEETWESLLAGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.5%) IPR014030 (14.5%) IPR014031 (14.5%)" "Beta-ketoacyl synthase (14.5%) Beta-ketoacyl synthase-like, N-terminal (14.5%) Beta-ketoacyl synthase, C-terminal (14.5%)" GLGVALLTPFNTDGSVDYQSLKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.3.3.7 (91.7%) 4.-.-.- (8.3%)" "4-hydroxy-tetrahydrodipicolinate synthase (91.7%) Lyases (8.3%)" "GO:0009089 (24.4%) GO:0019877 (24.4%)" GO:0005829 (24.4%) "GO:0008840 (24.4%) GO:0016829 (2.2%)" "lysine biosynthetic process via diaminopimelate (24.4%) diaminopimelate biosynthetic process (24.4%)" cytosol (24.4%) "4-hydroxy-tetrahydrodipicolinate synthase activity (24.4%) lyase activity (2.2%)" "IPR002220 (26.7%) IPR005263 (24.4%) IPR013785 (24.4%)" "DapA-like (26.7%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (24.4%) Aldolase-type TIM barrel (24.4%)" MLGFLMEK root 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.6%) GO:0006096 (16.6%)" GO:0005829 (16.6%) "GO:0004618 (16.6%) GO:0005524 (16.6%) GO:0043531 (16.6%)" "gluconeogenesis (16.6%) glycolytic process (16.6%)" cytosol (16.6%) "phosphoglycerate kinase activity (16.6%) ATP binding (16.6%) ADP binding (16.6%)" "IPR001576 (32.8%) IPR015824 (32.8%) IPR036043 (32.8%)" "Phosphoglycerate kinase (32.8%) Phosphoglycerate kinase, N-terminal (32.8%) Phosphoglycerate kinase superfamily (32.8%)" AFMPYGGLK Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.8%) GO:0005829 (33.4%) "GO:0008861 (33.4%) GO:0016829 (0.4%)" glucose metabolic process (32.8%) cytosol (33.4%) "formate C-acetyltransferase activity (33.4%) lyase activity (0.4%)" "IPR004184 (20.2%) IPR050244 (20.2%) IPR001150 (19.9%)" "Pyruvate formate lyase domain (20.2%) Autonomous Glycyl Radical Cofactor (20.2%) Glycine radical domain (19.9%)" NFDEDELELLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0003677 (100%) DNA binding (100%) "IPR001647 (33.3%) IPR009057 (33.3%) IPR050624 (33.3%)" "DNA-binding HTH domain, TetR-type (33.3%) Homedomain-like superfamily (33.3%) HTH-type Transcriptional Regulator (33.3%)" ALLDYLYDRDLNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25.6%) GO:0022627 (25.6%) "GO:0003735 (25.6%) GO:0019843 (23.3%)" translation (25.6%) cytosolic small ribosomal subunit (25.6%) "structural constituent of ribosome (25.6%) rRNA binding (23.3%)" "IPR000589 (33.3%) IPR005290 (33.3%) IPR009068 (33.3%)" "Small ribosomal subunit protein uS15 (33.3%) Small ribosomal subunit protein uS15, bacteria (33.3%) uS15/NS1, RNA-binding domain superfamily (33.3%)" KGENDYADDLNTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016829 (100%) lyase activity (100%) "IPR003961 (25.6%) IPR033803 (25.6%) IPR013783 (24.4%)" "Fibronectin type III (25.6%) Golvesin/Xly, CBD-like (25.6%) Immunoglobulin-like fold (24.4%)" MSGLATMTAK Bacteria Bacteria 2.4.2.19 (100%) nicotinate-nucleotide diphosphorylase (carboxylating) (100%) "GO:0009435 (25%) GO:0034213 (25%)" GO:0005737 (25%) GO:0004514 (25%) "NAD+ biosynthetic process (25%) quinolinate catabolic process (25%)" cytoplasm (25%) nicotinate-nucleotide diphosphorylase (carboxylating) activity (25%) "IPR022412 (15%) IPR027277 (15%) IPR002638 (14.3%)" "Quinolinate phosphoribosyl transferase, N-terminal (15%) Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD (15%) Quinolinate phosphoribosyl transferase, C-terminal (14.3%)" MWAPDMLQYTSDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" TLLEALNTDLVCDALNTAMR root "GO:0016226 (32.7%) GO:0006879 (0.5%)" GO:0005737 (0.5%) "GO:0005506 (32.7%) GO:0051536 (32.7%) GO:0008198 (0.5%)" "iron-sulfur cluster assembly (32.7%) intracellular iron ion homeostasis (0.5%)" cytoplasm (0.5%) "iron ion binding (32.7%) iron-sulfur cluster binding (32.7%) ferrous iron binding (0.5%)" IPR002871 (100%) NIF system FeS cluster assembly, NifU, N-terminal (100%) YTVPVVFR Bacteria Bacteria "GO:0015031 (18.9%) GO:0055085 (18.9%) GO:0015891 (9.1%)" "GO:0098797 (19.2%) GO:0030288 (9.1%) GO:0005737 (0.8%)" "GO:0031992 (18.9%) GO:0003824 (0.8%) GO:0031177 (0.8%)" "protein transport (18.9%) transmembrane transport (18.9%) siderophore transport (9.1%)" "plasma membrane protein complex (19.2%) outer membrane-bounded periplasmic space (9.1%) cytoplasm (0.8%)" "energy transducer activity (18.9%) catalytic activity (0.8%) phosphopantetheine binding (0.8%)" "IPR006260 (23.9%) IPR037682 (23.9%) IPR051045 (23.9%)" "TonB/TolA, C-terminal (23.9%) TonB, C-terminal (23.9%) TonB-dependent transporter energy transducer (23.9%)" DDLHDWLGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (33.9%) "GO:0004553 (33.9%) GO:0030246 (32.1%)" carbohydrate metabolic process (33.9%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.9%) carbohydrate binding (32.1%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" LFVEEGLLK root "GO:0006779 (3.2%) GO:0015074 (3.2%) GO:0006355 (1.6%)" "GO:0005737 (6.3%) GO:0005634 (3.2%) GO:0016020 (1.6%)" "GO:0030170 (31.7%) GO:0008483 (28.6%) GO:0003676 (3.2%)" "porphyrin-containing compound biosynthetic process (3.2%) DNA integration (3.2%) regulation of DNA-templated transcription (1.6%)" "cytoplasm (6.3%) nucleus (3.2%) membrane (1.6%)" "pyridoxal phosphate binding (31.7%) transaminase activity (28.6%) nucleic acid binding (3.2%)" "IPR001917 (12.4%) IPR004839 (12.4%) IPR015422 (12.4%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (12.4%) Aminotransferase, class I/classII, large domain (12.4%) Pyridoxal phosphate-dependent transferase, small domain (12.4%)" WAETVPYTFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" "GO:0008880 (33.3%) GO:0016853 (0.2%)" "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" "glucuronate isomerase activity (33.3%) isomerase activity (0.2%)" "IPR003766 (50.3%) IPR032466 (49.7%)" "Uronate isomerase (50.3%) Metal-dependent hydrolase (49.7%)" LVPADHLFLNTNEEYVQLVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.13 (100%) mannose-1-phosphate guanylyltransferase (100%) GO:0009298 (40.9%) "GO:0004475 (40.9%) GO:0005525 (15.9%) GO:0016853 (2.3%)" GDP-mannose biosynthetic process (40.9%) "mannose-1-phosphate guanylyltransferase (GTP) activity (40.9%) GTP binding (15.9%) isomerase activity (2.3%)" "IPR005835 (25.4%) IPR029044 (25.4%) IPR051161 (25.4%)" "Nucleotidyl transferase domain (25.4%) Nucleotide-diphospho-sugar transferases (25.4%) Mannose-6-phosphate isomerase type 2 (25.4%)" DKNVEPTLAALQGAAQTGEVGDGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006808 (25%) GO:0005829 (25%) "GO:0005524 (25%) GO:0030234 (25%)" regulation of nitrogen utilization (25%) cytosol (25%) "ATP binding (25%) enzyme regulator activity (25%)" "IPR002187 (25%) IPR011322 (25%) IPR015867 (25%)" "Nitrogen regulatory protein PII (25%) Nitrogen regulatory PII-like, alpha/beta (25%) Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal (25%)" YYSNLVGK Bacteria Bacteria "1.-.-.- (54.2%) 1.6.3.- (16.7%) 2.5.1.26 (12.5%)" "Oxidoreductases (54.2%) With oxygen as acceptor (16.7%) alkylglycerone-phosphate synthase (12.5%)" "GO:0009307 (0%) GO:0032259 (0%) GO:0044027 (0%)" "GO:0010181 (25%) GO:0009055 (24.7%) GO:0046872 (24.6%)" "DNA restriction-modification system (0%) methylation (0%) negative regulation of gene expression via chromosomal CpG island methylation (0%)" "FMN binding (25%) electron transfer activity (24.7%) metal ion binding (24.6%)" "IPR036866 (14.8%) IPR045761 (14.8%) IPR001279 (14.8%)" "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like (14.8%) ODP domain (14.8%) Metallo-beta-lactamase (14.8%)" VGDTPELVDLTNTAETAYTLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri EQFQLSDFKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0000049 (20%) GO:0003735 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "tRNA binding (20%) structural constituent of ribosome (20%)" "IPR001848 (25%) IPR018268 (25%) IPR027486 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10, conserved site (25%) Small ribosomal subunit protein uS10 domain (25%)" TNGSVQAALAAFPAVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" FTGQLNADYDVYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" TLEPLFTPQGFDWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (25.4%) "GO:0015093 (25.4%) GO:0005525 (24.6%) GO:0046914 (24.6%)" plasma membrane (25.4%) "ferrous iron transmembrane transporter activity (25.4%) GTP binding (24.6%) transition metal ion binding (24.6%)" "IPR011640 (9.5%) IPR011642 (9.5%) IPR050860 (9.5%)" "Ferrous iron transport protein B, C-terminal (9.5%) Nucleoside transporter/FeoB GTPase, Gate domain (9.5%) Fe(2+) Transporter FeoB GTPase (9.5%)" VYLRPETAQGLFVDYLSVQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0005737 (12.5%) GO:0070062 (12.5%) GO:1990742 (12.5%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "cytoplasm (12.5%) extracellular exosome (12.5%) microvesicle (12.5%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.3%) IPR002315 (11.3%) IPR004154 (11.3%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.3%) Glycyl-tRNA synthetase (11.3%) Anticodon-binding (11.3%)" QLNTAWYVFGTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae QSLSMDGQQLANYDAQNFNSLPLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" LLELTPSGTLDK Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (20.1%) IPR003593 (20.1%) IPR032781 (20.1%)" "ABC transporter-like, ATP-binding domain (20.1%) AAA+ ATPase domain (20.1%) ABC-transporter extension domain (20.1%)" VLEFDLK root "2.7.7.49 (83.5%) 3.1.3.16 (1.6%) 2.5.1.18 (1.2%)" "RNA-directed DNA polymerase (83.5%) protein-serine/threonine phosphatase (1.6%) glutathione transferase (1.2%)" "GO:0007009 (13.2%) GO:0061025 (6.2%) GO:0051607 (3.4%)" "GO:0005886 (14.3%) GO:0030659 (13.1%) GO:0016020 (3.6%)" "GO:0046872 (12.4%) GO:0003964 (6.5%) GO:0003723 (3.4%)" "plasma membrane organization (13.2%) membrane fusion (6.2%) defense response to virus (3.4%)" "plasma membrane (14.3%) cytoplasmic vesicle membrane (13.1%) membrane (3.6%)" "metal ion binding (12.4%) RNA-directed DNA polymerase activity (6.5%) RNA binding (3.4%)" "IPR000008 (4.8%) IPR037721 (4.8%) IPR006614 (4.8%)" "C2 domain (4.8%) Ferlin family (4.8%) Peroxin/Ferlin domain (4.8%)" AEEAPVAETEAPATEEAPKAE Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR000456 (33.3%) IPR036373 (33.3%) IPR047859 (33.3%)" "Large ribosomal subunit protein bL17 (33.3%) Large ribosomal subunit protein bL17 superfamily (33.3%) Large ribosomal subunit protein bL17, conserved site (33.3%)" SGMGYCGAATLENLHNAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006177 (20%) GO:0006183 (20%)" "GO:0000166 (20%) GO:0003938 (20%) GO:0046872 (20%)" "GMP biosynthetic process (20%) GTP biosynthetic process (20%)" "nucleotide binding (20%) IMP dehydrogenase activity (20%) metal ion binding (20%)" "IPR000644 (17.4%) IPR001093 (17.4%) IPR005990 (17.4%)" "CBS domain (17.4%) IMP dehydrogenase/GMP reductase (17.4%) Inosine-5'-monophosphate dehydrogenase (17.4%)" EHAAWALAGAGFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.33 (100%) 3-isopropylmalate dehydratase (100%) GO:0009098 (33.3%) GO:0009316 (33.3%) GO:0003861 (33.3%) L-leucine biosynthetic process (33.3%) 3-isopropylmalate dehydratase complex (33.3%) 3-isopropylmalate dehydratase activity (33.3%) "IPR000573 (20%) IPR004431 (20%) IPR015928 (20%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (20%) 3-isopropylmalate dehydratase, small subunit (20%) Aconitase/3-isopropylmalate dehydratase, swivel (20%)" LGAELKPVDMLSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) VLTDNGAELLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0070181 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) small ribosomal subunit rRNA binding (16.7%)" "IPR000529 (25%) IPR014717 (25%) IPR020814 (25%)" "Small ribosomal subunit protein bS6 (25%) Translation elongation factor EF1B/small ribosomal subunit protein bS6 (25%) Small ribosomal subunit protein bS6, plastid/chloroplast (25%)" ATLAVEGLEQYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (34.8%) IPR011042 (32.6%) IPR029058 (32.6%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (34.8%) Six-bladed beta-propeller, TolB-like (32.6%) Alpha/Beta hydrolase fold (32.6%)" LTNLPNPLDTHVFCPQDQAEAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.-.- (100%) Glycosyltransferases (100%) GO:0016757 (100%) glycosyltransferase activity (100%) IPR028098 (100%) Glycosyltransferase subfamily 4-like, N-terminal domain (100%) AQEEANGGDFVSLFLNAYHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006605 (20%) GO:0043952 (20%) GO:0065002 (20%)" GO:0005886 (20%) GO:0015450 (20%) "protein targeting (20%) protein transport by the Sec complex (20%) intracellular protein transmembrane transport (20%)" plasma membrane (20%) protein-transporting ATPase activity (20%) "IPR005665 (11.2%) IPR005791 (11.2%) IPR022646 (11.2%)" "Protein-export membrane protein SecF, bacterial (11.2%) Protein translocase subunit SecD (11.2%) Protein-export membrane protein SecD/SecF/SecDF, conserved site (11.2%)" AYLVNTGWNGTGK root 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.5%) "GO:0005829 (17.5%) GO:0005737 (0%)" "GO:0004612 (17.5%) GO:0005524 (17.5%) GO:0046872 (16.8%)" gluconeogenesis (17.5%) "cytosol (17.5%) cytoplasm (0%)" "phosphoenolpyruvate carboxykinase (ATP) activity (17.5%) ATP binding (17.5%) metal ion binding (16.8%)" "IPR001272 (25.4%) IPR013035 (25.4%) IPR015994 (24.6%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.4%) Phosphoenolpyruvate carboxykinase, C-terminal (25.4%) Phosphoenolpyruvate carboxykinase (ATP), conserved site (24.6%)" MAMNLPDYWLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.18 (100%) 1,4-alpha-glucan branching enzyme (100%) "GO:0005978 (19.8%) GO:0005975 (0.4%)" "GO:0005737 (20.1%) GO:0016020 (0.1%)" "GO:0003844 (20.1%) GO:0004553 (19.8%) GO:0043169 (19.7%)" "glycogen biosynthetic process (19.8%) carbohydrate metabolic process (0.4%)" "cytoplasm (20.1%) membrane (0.1%)" "1,4-alpha-glucan branching enzyme activity (20.1%) hydrolase activity, hydrolyzing O-glycosyl compounds (19.8%) cation binding (19.7%)" "IPR017853 (12.6%) IPR006047 (12.6%) IPR004193 (12.5%)" "Glycoside hydrolase superfamily (12.6%) Glycosyl hydrolase family 13, catalytic domain (12.6%) Glycoside hydrolase, family 13, N-terminal (12.5%)" FTEYKPLSYGLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005975 (50%) "GO:0004553 (34.4%) GO:0004565 (15.6%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34.4%) beta-galactosidase activity (15.6%)" "IPR001944 (14.3%) IPR008979 (14.3%) IPR017853 (14.3%)" "Glycoside hydrolase, family 35 (14.3%) Galactose-binding-like domain superfamily (14.3%) Glycoside hydrolase superfamily (14.3%)" ATCPLVLDADALNLLSSHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "4.2.1.136 (50%) 5.1.99.6 (50%)" "ADP-dependent NAD(P)H-hydrate dehydratase (50%) NAD(P)H-hydrate epimerase (50%)" "GO:0110051 (16.8%) GO:0046496 (16.2%)" "GO:0005524 (16.8%) GO:0052855 (16.8%) GO:0052856 (16.8%)" "metabolite repair (16.8%) nicotinamide nucleotide metabolic process (16.2%)" "ATP binding (16.8%) ADP-dependent NAD(P)H-hydrate dehydratase activity (16.8%) NAD(P)HX epimerase activity (16.8%)" "IPR000631 (17%) IPR029056 (17%) IPR004443 (16.5%)" "ATP/ADP-dependent (S)-NAD(P)H-hydrate dehydratase (17%) Ribokinase-like (17%) YjeF N-terminal domain (16.5%)" FADYELK root "6.1.1.15 (99.7%) 3.4.24.- (0.3%)" "proline--tRNA ligase (99.7%) Metalloendopeptidases (0.3%)" "GO:0006433 (17.7%) GO:0006518 (0.1%) GO:0000041 (0.1%)" "GO:0005737 (18%) GO:0017101 (17.7%) GO:0005829 (1.2%)" "GO:0005524 (18.3%) GO:0004827 (17.7%) GO:0003700 (0.6%)" "prolyl-tRNA aminoacylation (17.7%) peptide metabolic process (0.1%) transition metal ion transport (0.1%)" "cytoplasm (18%) aminoacyl-tRNA synthetase multienzyme complex (17.7%) cytosol (1.2%)" "ATP binding (18.3%) proline-tRNA ligase activity (17.7%) DNA-binding transcription factor activity (0.6%)" "IPR004154 (10%) IPR004499 (10%) IPR016061 (9.9%)" "Anticodon-binding (10%) Proline-tRNA ligase, class IIa, archaeal-type (10%) Proline-tRNA ligase, class II, C-terminal (9.9%)" SLPSYFGTTAPTLNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" LDVVVQTSGQLR Pseudomonadati Bacteria Pseudomonadati 6.6.1.2 (100%) cobaltochelatase (100%) GO:0016020 (90.7%) "GO:0051116 (8.7%) GO:0016874 (0.7%)" membrane (90.7%) "cobaltochelatase activity (8.7%) ligase activity (0.7%)" IPR003672 (100%) CobN/magnesium chelatase (100%) YLAENYPESYDHAVPDELVYSGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.7%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.7%)" "IPR004733 (20%) IPR010918 (20%) IPR016188 (20%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20%) PurM-like, C-terminal domain (20%) PurM-like, N-terminal domain (20%)" FLTEKEVDMLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.- (100%) Transferring other groups (100%) "GO:0000455 (32.1%) GO:0001522 (0.7%) GO:0006364 (0.7%)" "GO:0003723 (32.9%) GO:0120159 (32.1%) GO:0009982 (0.7%)" "enzyme-directed rRNA pseudouridine synthesis (32.1%) pseudouridine synthesis (0.7%) rRNA processing (0.7%)" "RNA binding (32.9%) rRNA pseudouridine synthase activity (32.1%) pseudouridine synthase activity (0.7%)" "IPR000748 (11.3%) IPR006145 (11.3%) IPR018496 (11.3%)" "Pseudouridine synthase, RsuA/RluB/E/F (11.3%) Pseudouridine synthase, RsuA/RluA-like (11.3%) Pseudouridine synthase, RsuA/RluB/E/F, conserved site (11.3%)" NAYDPQFNVDGVWDKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" FLAQADGSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.7%) IPR012910 (20.7%) IPR039426 (20.7%)" "TonB-dependent receptor-like, beta-barrel (20.7%) TonB-dependent receptor, plug domain (20.7%) TonB-dependent receptor-like (20.7%)" HSFAVVLGQSAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" EVGECMSNYVGLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.3.16 (100%) L-aspartate oxidase (100%) GO:0034628 (34.3%) GO:0005737 (31.4%) GO:0008734 (34.3%) 'de novo' NAD+ biosynthetic process from L-aspartate (34.3%) cytoplasm (31.4%) L-aspartate oxidase activity (34.3%) "IPR005288 (17.4%) IPR015939 (17.4%) IPR003953 (16.7%)" "L-aspartate oxidase (17.4%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (17.4%) FAD-dependent oxidoreductase 2, FAD-binding domain (16.7%)" DNQESLNAAQYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" QTVAQYLASQSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (48.7%) GO:0003746 (51.3%) cytoplasm (48.7%) translation elongation factor activity (51.3%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" TGGLSGPCVKPVALR Bacteria Bacteria "1.3.-.- (90.6%) 1.3.1.14 (9.4%)" "Acting on the CH-CH group of donors (90.6%) dihydroorotate dehydrogenase (NAD(+)) (9.4%)" "GO:0006207 (25%) GO:0044205 (25%)" GO:0005737 (25%) "GO:0004152 (24.2%) GO:0004589 (0.8%)" "'de novo' pyrimidine nucleobase biosynthetic process (25%) 'de novo' UMP biosynthetic process (25%)" cytoplasm (25%) "dihydroorotate dehydrogenase activity (24.2%) dihydroorotate dehydrogenase (NAD+) activity (0.8%)" "IPR005720 (12.6%) IPR012135 (12.6%) IPR013785 (12.6%)" "Dihydroorotate dehydrogenase, catalytic (12.6%) Dihydroorotate dehydrogenase, class 1/ 2 (12.6%) Aldolase-type TIM barrel (12.6%)" LLDMLKPSVVHVLYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (31.6%) IPR010230 (31.6%) IPR027417 (31.6%)" "ABC transporter-like, ATP-binding domain (31.6%) FeS cluster assembly SUF system, ATPase SufC (31.6%) P-loop containing nucleoside triphosphate hydrolase (31.6%)" TLDELKEQYVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" MDELGFGNCTNTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.3.5.1 (36.5%) 1.3.99.1 (36.5%) 1.3.5.4 (27%)" "succinate dehydrogenase (36.5%) Deleted entry (36.5%) Transferred entry: 1.3.5.1 (27%)" "GO:0022904 (23.6%) GO:0009060 (23.1%) GO:0006099 (0.5%)" "GO:0009055 (23.2%) GO:0051537 (23.2%) GO:0016491 (2.9%)" "respiratory electron transport chain (23.6%) aerobic respiration (23.1%) tricarboxylic acid cycle (0.5%)" "electron transfer activity (23.2%) 2 iron, 2 sulfur cluster binding (23.2%) oxidoreductase activity (2.9%)" "IPR009051 (14.2%) IPR017896 (14.1%) IPR050573 (14%)" "Alpha-helical ferredoxin (14.2%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.1%) Succinate Dehydrogenase/Fumarate Reductase Iron-Sulfur (14%)" NTTLTLPAHDLPSFKPSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0030261 (23.1%) GO:0005829 (23.1%) "GO:0003677 (26.9%) GO:0030527 (26.9%)" chromosome condensation (23.1%) cytosol (23.1%) "DNA binding (26.9%) structural constituent of chromatin (26.9%)" "IPR000119 (53.8%) IPR010992 (46.2%)" "Histone-like DNA-binding protein (53.8%) Integration host factor (IHF)-like DNA-binding domain superfamily (46.2%)" AMAYFYLVR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.6%) IPR012944 (33.2%) IPR033985 (33.2%)" "Tetratricopeptide-like helical domain superfamily (33.6%) RagB/SusD domain (33.2%) SusD-like, N-terminal (33.2%)" FLTENGLENTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "6.3.5.5 (96.7%) 6.3.4.16 (3.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (96.7%) carbamoyl-phosphate synthase (ammonia) (3.3%)" "GO:0006541 (14.3%) GO:0006526 (13.3%) GO:0006221 (12.9%)" GO:0005737 (14.3%) "GO:0004088 (14.3%) GO:0005524 (14.3%) GO:0046872 (13.3%)" "glutamine metabolic process (14.3%) L-arginine biosynthetic process (13.3%) pyrimidine nucleotide biosynthetic process (12.9%)" cytoplasm (14.3%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.3%) ATP binding (14.3%) metal ion binding (13.3%)" "IPR011607 (10.8%) IPR036914 (10.8%) IPR005479 (10.1%)" "Methylglyoxal synthase-like domain (10.8%) Methylglyoxal synthase-like domain superfamily (10.8%) Carbamoyl phosphate synthase, ATP-binding domain (10.1%)" DVYPEPMQDFPVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) GO:0006432 (16.7%) GO:0009328 (16.7%) "GO:0000287 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" phenylalanyl-tRNA aminoacylation (16.7%) phenylalanine-tRNA ligase complex (16.7%) "magnesium ion binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR005146 (8%) IPR005147 (8%) IPR045060 (8%)" "B3/B4 tRNA-binding domain (8%) tRNA synthetase, B5-domain (8%) Phenylalanine-tRNA ligase, class IIc, beta subunit (8%)" EPGAEGEPLYLDVK Bacteria Bacteria "1.2.7.1 (90.3%) 1.2.7.- (6.5%) 1.2.1.51 (3.2%)" "pyruvate synthase (90.3%) With an iron-sulfur protein as acceptor (6.5%) pyruvate dehydrogenase (NADP(+)) (3.2%)" "GO:0006979 (14.8%) GO:0022900 (14.6%) GO:0044281 (11.5%)" "GO:0051539 (14.8%) GO:0005506 (14.6%) GO:0030976 (14.5%)" "response to oxidative stress (14.8%) electron transport chain (14.6%) small molecule metabolic process (11.5%)" "4 iron, 4 sulfur cluster binding (14.8%) iron ion binding (14.6%) thiamine pyrophosphate binding (14.5%)" "IPR002880 (7.9%) IPR033412 (7.9%) IPR050722 (7.9%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.9%) Pyruvate:ferredoxin oxidoreductase, core domain II (7.9%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.9%)" GLMTVEQAAQLAQAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (25%) IPR001179 (25%) IPR036944 (25%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (25%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (25%) Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily (25%)" KMNNTWLQNNLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SACMGECLTWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR033985 (33.8%) IPR012944 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) SusD-like, N-terminal (33.8%) RagB/SusD domain (32.4%)" MPELEKDGSLQNVLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.9%) IPR004659 (25.9%) IPR019307 (25.9%)" "S1 domain (25.9%) Ribonuclease E/G (25.9%) RNA-binding protein AU-1/Ribonuclease E/G (25.9%)" QNLTEVALDYLSAGLDPQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.1.1.2 (100%) tryptophan--tRNA ligase (100%) GO:0006436 (25%) GO:0005829 (25%) "GO:0004830 (25%) GO:0005524 (25%)" tryptophanyl-tRNA aminoacylation (25%) cytosol (25%) "tryptophan-tRNA ligase activity (25%) ATP binding (25%)" "IPR001412 (20.2%) IPR002305 (20.2%) IPR002306 (20.2%)" "Aminoacyl-tRNA synthetase, class I, conserved site (20.2%) Aminoacyl-tRNA synthetase, class Ic (20.2%) Tryptophan-tRNA ligase (20.2%)" EVWNLAPADHPAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (31.9%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (31.9%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" NLGLMAHLDAGK root "3.6.5.- (83.3%) 3.6.5.3 (16.7%)" "Acting on GTP; involved in cellular and subcellular movement (83.3%) protein-synthesizing GTPase (16.7%)" "GO:0032790 (19.8%) GO:0032543 (1.7%) GO:0006412 (0.3%)" "GO:0005737 (16.7%) GO:0005759 (1.6%) GO:0009507 (0.6%)" "GO:0005525 (19.9%) GO:0003924 (19.9%) GO:0003746 (18.1%)" "ribosome disassembly (19.8%) mitochondrial translation (1.7%) translation (0.3%)" "cytoplasm (16.7%) mitochondrial matrix (1.6%) chloroplast (0.6%)" "GTP binding (19.9%) GTPase activity (19.9%) translation elongation factor activity (18.1%)" "IPR000795 (6.4%) IPR027417 (6.4%) IPR005225 (6.4%)" "Translational (tr)-type GTP-binding domain (6.4%) P-loop containing nucleoside triphosphate hydrolase (6.4%) Small GTP-binding domain (6.4%)" LPEGPVAEKWTNYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (15.7%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (15.7%)" "IPR003953 (14.4%) IPR030664 (14.4%) IPR036188 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) FAD/NAD(P)-binding domain superfamily (14.3%)" VTDFLSDMGAAYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.4.1.227 (96.9%) 2.4.-.- (3.1%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (96.9%) Glycosyltransferases (3.1%)" "GO:0005975 (12%) GO:0008360 (12%) GO:0009252 (12%)" GO:0005886 (12%) "GO:0050511 (12%) GO:0051991 (3.2%) GO:0016758 (0.4%)" "carbohydrate metabolic process (12%) regulation of cell shape (12%) peptidoglycan biosynthetic process (12%)" plasma membrane (12%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (3.2%) hexosyltransferase activity (0.4%)" "IPR007235 (34.1%) IPR004276 (33%) IPR006009 (33%)" "Glycosyl transferase, family 28, C-terminal (34.1%) Glycosyltransferase family 28, N-terminal domain (33%) N-acetylglucosaminyltransferase, MurG (33%)" SALVDAFYQNLEFGTGGLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.4.2.- (100%) Phosphotransferases (phosphomutases) (100%) "GO:0005975 (25%) GO:0006166 (25%)" "GO:0000287 (25%) GO:0008973 (25%)" "carbohydrate metabolic process (25%) purine ribonucleoside salvage (25%)" "magnesium ion binding (25%) phosphopentomutase activity (25%)" "IPR005844 (14.9%) IPR016066 (14.9%) IPR005845 (14.3%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I (14.9%) Alpha-D-phosphohexomutase, conserved site (14.9%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (14.3%)" LGDHYSEGCNNLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009294 (100%) DNA-mediated transformation (100%) "IPR003488 (50%) IPR057666 (50%)" "DNA recombination-mediator protein A (50%) Smf/DprA, SLOG domain (50%)" LRDLGHEYGAVTGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0004019 (16.7%) GO:0005525 (16.7%) GO:0000287 (16.6%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "adenylosuccinate synthase activity (16.7%) GTP binding (16.7%) magnesium ion binding (16.6%)" "IPR001114 (14.3%) IPR027417 (14.3%) IPR033128 (14.3%)" "Adenylosuccinate synthetase (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%) Adenylosuccinate synthase, active site (14.3%)" LASMDLTALR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.5.1.2 (50.8%) 4.3.3.6 (49.2%)" "glutaminase (50.8%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (49.2%)" "GO:0008614 (14.2%) GO:0042823 (14.2%) GO:0006543 (13.8%)" "GO:0005829 (14.2%) GO:1903600 (14.2%)" "GO:0004359 (14.2%) GO:0036381 (13.8%) GO:0016740 (0.9%)" "pyridoxine metabolic process (14.2%) pyridoxal phosphate biosynthetic process (14.2%) L-glutamine catabolic process (13.8%)" "cytosol (14.2%) glutaminase complex (14.2%)" "glutaminase activity (14.2%) pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (13.8%) transferase activity (0.9%)" "IPR002161 (33.7%) IPR021196 (33.7%) IPR029062 (32.6%)" "Pyridoxal 5'-phosphate synthase subunit PdxT/SNO (33.7%) PdxT/SNO family, conserved site (33.7%) Class I glutamine amidotransferase-like (32.6%)" YGEEGDKLLFK root 6.1.1.21 (100%) histidine--tRNA ligase (100%) GO:0006427 (24.9%) GO:0005737 (25%) "GO:0004821 (25%) GO:0005524 (24.9%) GO:0004812 (0.1%)" histidyl-tRNA aminoacylation (24.9%) cytoplasm (25%) "histidine-tRNA ligase activity (25%) ATP binding (24.9%) aminoacyl-tRNA ligase activity (0.1%)" "IPR041715 (12.7%) IPR045864 (12.6%) IPR015807 (12.6%)" "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain (12.7%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (12.6%) Histidine-tRNA ligase (12.6%)" SLLTGSAWR root 6.3.2.6 (100%) phosphoribosylaminoimidazolesuccinocarboxamide synthase (100%) "GO:0006189 (24.8%) GO:0006656 (0.2%)" "GO:0005737 (24.8%) GO:0012505 (0.2%) GO:0016020 (0.2%)" "GO:0004639 (24.8%) GO:0005524 (24.8%)" "'de novo' IMP biosynthetic process (24.8%) phosphatidylcholine biosynthetic process (0.2%)" "cytoplasm (24.8%) endomembrane system (0.2%) membrane (0.2%)" "phosphoribosylaminoimidazolesuccinocarboxamide synthase activity (24.8%) ATP binding (24.8%)" "IPR028923 (49.8%) IPR018236 (49.3%) IPR007318 (0.4%)" "SAICAR synthetase/ADE2, N-terminal (49.8%) SAICAR synthetase, conserved site (49.3%) Phospholipid methyltransferase (0.4%)" YGLGHLSTGDVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.4.3 (97.3%) 2.7.4.- (2.7%)" "adenylate kinase (97.3%) Phosphotransferases with a phosphate group as acceptor (2.7%)" "GO:0044209 (24.1%) GO:0006139 (0.8%) GO:0006166 (0.8%)" GO:0005737 (24.1%) "GO:0005524 (24.8%) GO:0004017 (24.1%) GO:0004422 (0.8%)" "AMP salvage (24.1%) nucleobase-containing compound metabolic process (0.8%) purine ribonucleoside salvage (0.8%)" cytoplasm (24.1%) "ATP binding (24.8%) AMP kinase activity (24.1%) hypoxanthine phosphoribosyltransferase activity (0.8%)" "IPR000850 (32.4%) IPR027417 (32.4%) IPR033690 (32.4%)" "Adenylate kinase/UMP-CMP kinase (32.4%) P-loop containing nucleoside triphosphate hydrolase (32.4%) Adenylate kinase, conserved site (32.4%)" NFELFDAATNTVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (25%) GO:0045493 (25%)" "GO:0009044 (25%) GO:0046556 (25%)" "arabinan catabolic process (25%) xylan catabolic process (25%)" "xylan 1,4-beta-xylosidase activity (25%) alpha-L-arabinofuranosidase activity (25%)" "IPR001764 (9.3%) IPR002772 (9.3%) IPR011658 (9.3%)" "Glycoside hydrolase, family 3, N-terminal (9.3%) Glycoside hydrolase family 3 C-terminal domain (9.3%) PA14 domain (9.3%)" LSEYAGTGPTEEQYKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (29.5%) GO:0009279 (36.4%) GO:0015344 (34.1%) siderophore transmembrane transport (29.5%) cell outer membrane (36.4%) siderophore uptake transmembrane transporter activity (34.1%) "IPR036942 (50.8%) IPR039426 (49.2%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50.8%) TonB-dependent receptor-like (49.2%)" LLFLEDYDMTLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" GLPCLYYGSEVGFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (76.5%) "GO:0016787 (20%) GO:0016829 (3.5%)" carbohydrate metabolic process (76.5%) "hydrolase activity (20%) lyase activity (3.5%)" "IPR013783 (24.4%) IPR017853 (24.4%) IPR006047 (23.6%)" "Immunoglobulin-like fold (24.4%) Glycoside hydrolase superfamily (24.4%) Glycosyl hydrolase family 13, catalytic domain (23.6%)" FVSALVVPEFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.2.1.3 (100%) long-chain-fatty-acid--CoA ligase (100%) "GO:0016020 (49.4%) GO:0005783 (1.1%)" GO:0004467 (49.4%) "membrane (49.4%) endoplasmic reticulum (1.1%)" long-chain fatty acid-CoA ligase activity (49.4%) "IPR000873 (33.6%) IPR020845 (33.6%) IPR042099 (32.8%)" "AMP-dependent synthetase/ligase domain (33.6%) AMP-binding, conserved site (33.6%) ANL, N-terminal domain (32.8%)" YAPGYYCDADGYSENAFNEEGYLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" DALGDTALR Bacteria Bacteria "3.6.3.14 (50%) 7.4.2.8 (50%)" "Transferred entry: 7.1.2.2 (50%) protein-secreting ATPase (50%)" GO:0030254 (11.9%) "GO:0005737 (11.9%) GO:0030257 (11.9%) GO:0045259 (11.9%)" "GO:0016301 (15.3%) GO:0005524 (11.9%) GO:0016887 (11.9%)" protein secretion by the type III secretion system (11.9%) "cytoplasm (11.9%) type III protein secretion system complex (11.9%) proton-transporting ATP synthase complex (11.9%)" "kinase activity (15.3%) ATP binding (11.9%) ATP hydrolysis activity (11.9%)" "IPR011611 (10.5%) IPR029056 (10.5%) IPR050306 (10.5%)" "Carbohydrate kinase PfkB (10.5%) Ribokinase-like (10.5%) PfkB Carbohydrate Kinase (10.5%)" ASQFSFAR root "6.3.5.5 (71.7%) 6.3.4.16 (28.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (71.7%) carbamoyl-phosphate synthase (ammonia) (28.3%)" "GO:0006541 (13.5%) GO:0006526 (13.2%) GO:0006221 (13%)" "GO:0005737 (13.4%) GO:0005951 (0.1%)" "GO:0004088 (13.5%) GO:0005524 (13.5%) GO:0046872 (13.5%)" "glutamine metabolic process (13.5%) L-arginine biosynthetic process (13.2%) pyrimidine nucleotide biosynthetic process (13%)" "cytoplasm (13.4%) carbamoyl-phosphate synthase complex (0.1%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.5%) ATP binding (13.5%) metal ion binding (13.5%)" "IPR005479 (10.1%) IPR011607 (10.1%) IPR011761 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Methylglyoxal synthase-like domain (10.1%) ATP-grasp fold (10.1%)" KEVLNEPELLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.95 (42.9%) 1.1.1.- (28.6%) 1.1.1.290 (28.6%)" "phosphoglycerate dehydrogenase (42.9%) With NAD(+) or NADP(+) as acceptor (28.6%) 4-phosphoerythronate dehydrogenase (28.6%)" "GO:0051287 (50%) GO:0016616 (45.5%) GO:0004617 (2.7%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (45.5%) phosphoglycerate dehydrogenase activity (2.7%)" "IPR006139 (27.5%) IPR006140 (27.5%) IPR036291 (27.5%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (27.5%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (27.5%) NAD(P)-binding domain superfamily (27.5%)" LDLYDPK root "3.1.1.- (45.1%) 1.1.1.22 (20%) 3.1.-.- (8.4%)" "Carboxylic ester hydrolases (45.1%) UDP-glucose 6-dehydrogenase (20%) Acting on ester bonds (8.4%)" "GO:0006581 (3.8%) GO:0019695 (3.8%) GO:0015031 (2.9%)" "GO:0016020 (25%) GO:0005886 (4.1%) GO:0005615 (4.1%)" "GO:0003990 (3.8%) GO:0031992 (2.4%) GO:0003979 (1.6%)" "acetylcholine catabolic process (3.8%) choline metabolic process (3.8%) protein transport (2.9%)" "membrane (25%) plasma membrane (4.1%) extracellular space (4.1%)" "acetylcholinesterase activity (3.8%) energy transducer activity (2.4%) UDP-glucose 6-dehydrogenase activity (1.6%)" "IPR026307 (9.1%) IPR055423 (9%) IPR055424 (9%)" "Transmembrane protein 132 (9.1%) Transmembrane protein TMEM132, fifth domain (9%) Transmembrane protein TMEM132, sixth domain (9%)" VCELLGLDQNNSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (17.4%) GO:0006085 (15.9%)" GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0008776 (17.4%) GO:0000287 (15.9%)" "acetate metabolic process (17.4%) acetyl-CoA biosynthetic process (15.9%)" cytoplasm (15.9%) "ATP binding (17.4%) acetate kinase activity (17.4%) magnesium ion binding (15.9%)" "IPR000890 (25.3%) IPR004372 (25.3%) IPR023865 (25.3%)" "Aliphatic acid kinase, short-chain (25.3%) Acetate/propionate kinase (25.3%) Aliphatic acid kinase, short-chain, conserved site (25.3%)" NVMLNASDANKPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0044718 (23.8%) GO:0006826 (2.4%)" GO:0009279 (38.8%) GO:0015344 (35%) "siderophore transmembrane transport (23.8%) iron ion transport (2.4%)" cell outer membrane (38.8%) siderophore uptake transmembrane transporter activity (35%) "IPR036942 (47.3%) IPR039426 (46.2%) IPR000531 (5.3%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (47.3%) TonB-dependent receptor-like (46.2%) TonB-dependent receptor-like, beta-barrel (5.3%)" EVLMAEDVEHLFGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" EAANWEYLVHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.4%) GO:0022900 (14.4%) GO:0044281 (13.8%)" "GO:0005506 (14.4%) GO:0030976 (14.4%) GO:0051539 (14.4%)" "response to oxidative stress (14.4%) electron transport chain (14.4%) small molecule metabolic process (13.8%)" "iron ion binding (14.4%) thiamine pyrophosphate binding (14.4%) 4 iron, 4 sulfur cluster binding (14.4%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" FPGGCYVEGQESPENAFHWEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (14.4%) IPR010720 (14.4%) IPR051563 (14.4%)" "Carbohydrate-binding, CenC-like (14.4%) Alpha-L-arabinofuranosidase, C-terminal (14.4%) Glycosyl Hydrolase Family 51 (14.4%)" TNYLFKEPMK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.11.1.15 (100%) Transferred entry: 1.11.1.24, 1.11.1.25, 1.11.1.26, 1.11.1.27, 1.11.1.2and 1.11.1.29 (100%) GO:0017004 (26.3%) GO:0030313 (26.3%) "GO:0016209 (22.8%) GO:0016491 (22.8%) GO:0004601 (1.8%)" cytochrome complex assembly (26.3%) cell envelope (26.3%) "antioxidant activity (22.8%) oxidoreductase activity (22.8%) peroxidase activity (1.8%)" "IPR036249 (25.8%) IPR025380 (24.2%) IPR050553 (24.2%)" "Thioredoxin-like superfamily (25.8%) Domain of unknown function DUF4369 (24.2%) Thioredoxin family ResA/DsbE subfamily (24.2%)" LETSPEDLAGMSAAEGLLTAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0016301 (25.3%) GO:0050242 (25.3%) GO:0005524 (24.8%)" "kinase activity (25.3%) pyruvate, phosphate dikinase activity (25.3%) ATP binding (24.8%)" "IPR008279 (10.2%) IPR010121 (10.2%) IPR018274 (10.2%)" "PEP-utilising enzyme, mobile domain (10.2%) Pyruvate, phosphate dikinase (10.2%) PEP-utilising enzyme, active site (10.2%)" LMLQEYLPLGQR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.51 (100%) alpha-L-fucosidase (100%) "GO:0006004 (25%) GO:0016139 (25%)" GO:0005764 (25%) GO:0004560 (25%) "fucose metabolic process (25%) glycoside catabolic process (25%)" lysosome (25%) alpha-L-fucosidase activity (25%) "IPR000933 (24.7%) IPR000421 (24.1%) IPR008979 (23.5%)" "Glycoside hydrolase, family 29 (24.7%) Coagulation factor 5/8, C-terminal domain (24.1%) Galactose-binding-like domain superfamily (23.5%)" FSDNFSAFAGVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (90%) IPR011250 (10%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (90%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (10%)" TDATDEELANAAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005886 (22%) GO:0016020 (3%)" "GO:0005524 (25%) GO:0015421 (25%) GO:0016887 (25%)" "plasma membrane (22%) membrane (3%)" "ATP binding (25%) ABC-type oligopeptide transporter activity (25%) ATP hydrolysis activity (25%)" "IPR003439 (14.8%) IPR003593 (14.8%) IPR011527 (14.8%)" "ABC transporter-like, ATP-binding domain (14.8%) AAA+ ATPase domain (14.8%) ABC transporter type 1, transmembrane domain (14.8%)" TSFALSLAK root "5.6.2.3 (93.9%) 3.6.4.12 (6.1%)" "DNA 5'-3' helicase (93.9%) DNA helicase (6.1%)" "GO:0006269 (12.4%) GO:0006260 (0.1%) GO:0006397 (0.1%)" "GO:0005829 (12.5%) GO:1990077 (12.4%) GO:0009535 (0.1%)" "GO:0005524 (12.6%) GO:0003678 (12.5%) GO:0003677 (12.4%)" "DNA replication, synthesis of primer (12.4%) DNA replication (0.1%) mRNA processing (0.1%)" "cytosol (12.5%) primosome complex (12.4%) chloroplast thylakoid membrane (0.1%)" "ATP binding (12.6%) DNA helicase activity (12.5%) DNA binding (12.4%)" "IPR007694 (14.7%) IPR027417 (14.7%) IPR007693 (14.6%)" "DNA helicase, DnaB-like, C-terminal (14.7%) P-loop containing nucleoside triphosphate hydrolase (14.7%) DNA helicase, DnaB-like, N-terminal (14.6%)" KDFDEQYTLDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (64.7%) IPR008160 (35.3%)" "Domain of unknown function DUF4988 (64.7%) Collagen triple helix repeat (35.3%)" GLSGTEWLTECVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016746 (100%) acyltransferase activity (100%) IPR045746 (100%) Putative acyltransferase ACT14924-like, acyltransferase domain (100%) NWLSNLK root "4.2.1.1 (25%) 5.6.2.4 (20.8%) 2.6.1.42 (12.5%)" "carbonic anhydrase (25%) DNA 3'-5' helicase (20.8%) branched-chain-amino-acid transaminase (12.5%)" "GO:0044718 (1.8%) GO:0015976 (1.4%) GO:0000725 (1.1%)" "GO:0009279 (19.7%) GO:0016020 (5%) GO:0005886 (3.9%)" "GO:0003824 (5.2%) GO:0005524 (2.9%) GO:0008270 (2.3%)" "siderophore transmembrane transport (1.8%) carbon utilization (1.4%) recombinational repair (1.1%)" "cell outer membrane (19.7%) membrane (5%) plasma membrane (3.9%)" "catalytic activity (5.2%) ATP binding (2.9%) zinc ion binding (2.3%)" "IPR012910 (7%) IPR023996 (7%) IPR023997 (7%)" "TonB-dependent receptor, plug domain (7%) TonB-dependent outer membrane protein, SusC/RagA (7%) TonB-dependent outer membrane protein SusC/RagA, conserved site (7%)" LTGLRPAFEQVDLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.1.3.2 (100%) UDP-glucose 4-epimerase (100%) GO:0006012 (33.3%) GO:0005829 (33.3%) GO:0003978 (33.3%) galactose metabolic process (33.3%) cytosol (33.3%) UDP-glucose 4-epimerase activity (33.3%) "IPR005886 (32.7%) IPR016040 (32.7%) IPR036291 (32.7%)" "UDP-glucose 4-epimerase (32.7%) NAD(P)-binding domain (32.7%) NAD(P)-binding domain superfamily (32.7%)" MYEFLEK root "2.1.1.72 (33.3%) 2.3.2.31 (33.3%) 5.6.2.4 (33.3%)" "site-specific DNA-methyltransferase (adenine-specific) (33.3%) RBR-type E3 ubiquitin transferase (33.3%) DNA 3'-5' helicase (33.3%)" "GO:0006412 (15.7%) GO:0002229 (0.2%) GO:0055085 (0.2%)" "GO:0005840 (15.7%) GO:1990904 (15.7%) GO:0005634 (0.7%)" "GO:0003735 (15.7%) GO:0000049 (15.1%) GO:0019843 (15.1%)" "translation (15.7%) defense response to oomycetes (0.2%) transmembrane transport (0.2%)" "ribosome (15.7%) ribonucleoprotein complex (15.7%) nucleus (0.7%)" "structural constituent of ribosome (15.7%) tRNA binding (15.1%) rRNA binding (15.1%)" "IPR002132 (17.3%) IPR022803 (17.3%) IPR031309 (17.3%)" "Large ribosomal subunit protein uL5 (17.3%) Large ribosomal subunit protein uL5 domain superfamily (17.3%) Large ribosomal subunit protein uL5, C-terminal (17.3%)" DYSGAELLTK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.7%) IPR007121 (7.7%) IPR007641 (7.7%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.7%) RNA polymerase, beta subunit, conserved site (7.7%) RNA polymerase Rpb2, domain 7 (7.7%)" LLAQTALQLLAEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" NVTGKDPDAYLADYR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.6.1.2 (100%) cobaltochelatase (100%) GO:0016020 (97.7%) GO:0051116 (2.3%) membrane (97.7%) cobaltochelatase activity (2.3%) IPR003672 (100%) CobN/magnesium chelatase (100%) AATDPALASVTPGEALAGSTLTLTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" LAEVSNDLLDQCVAQGVPFAR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.3.5.1 (100%) succinate dehydrogenase (100%) GO:0009061 (20%) GO:0005886 (20%) "GO:0009055 (20%) GO:0050660 (20%) GO:0000104 (14.7%)" anaerobic respiration (20%) plasma membrane (20%) "electron transfer activity (20%) flavin adenine dinucleotide binding (20%) succinate dehydrogenase activity (14.7%)" "IPR003953 (14.4%) IPR011280 (14.4%) IPR015939 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria (14.4%) Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal (14.4%)" MNLDLLTALSPLDGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (21.5%) GO:0044208 (21.5%) GO:0006188 (12.3%)" "GO:0004018 (33.8%) GO:0070626 (9.2%) GO:0016829 (1.5%)" "'de novo' IMP biosynthetic process (21.5%) 'de novo' AMP biosynthetic process (21.5%) IMP biosynthetic process (12.3%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (33.8%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (9.2%) lyase activity (1.5%)" "IPR008948 (12.8%) IPR022761 (12.8%) IPR024083 (12.8%)" "L-Aspartase-like (12.8%) Fumarate lyase, N-terminal (12.8%) Fumarase/histidase, N-terminal (12.8%)" QEFMSLLR root 3.5.4.16 (100%) GTP cyclohydrolase I (100%) "GO:0006729 (14.2%) GO:0006730 (14.2%) GO:0046654 (14.2%)" GO:0005737 (14.2%) "GO:0003934 (14.2%) GO:0005525 (14.2%) GO:0008270 (14.2%)" "tetrahydrobiopterin biosynthetic process (14.2%) one-carbon metabolic process (14.2%) tetrahydrofolate biosynthetic process (14.2%)" cytoplasm (14.2%) "GTP cyclohydrolase I activity (14.2%) GTP binding (14.2%) zinc ion binding (14.2%)" "IPR001474 (19.9%) IPR018234 (19.9%) IPR020602 (19.9%)" "GTP cyclohydrolase I (19.9%) GTP cyclohydrolase I, conserved site (19.9%) GTP cyclohydrolase I domain (19.9%)" KPLDFSQGTYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.5%) IPR046357 (25.5%) IPR027304 (24.5%)" "Periplasmic chaperone PpiD (26.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.5%) Trigger factor/SurA domain superfamily (24.5%)" LQSLHFDATEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045900 (33.3%) GO:0022627 (33.3%) GO:0043024 (33.3%) negative regulation of translational elongation (33.3%) cytosolic small ribosomal subunit (33.3%) ribosomal small subunit binding (33.3%) "IPR003489 (45.2%) IPR036567 (45.2%) IPR050574 (9.5%)" "Ribosome hibernation promoting factor/RaiA (45.2%) Ribosome hibernation promotion factor-like (45.2%) HPF/YfiA ribosome-associated (9.5%)" SPVLLQVSK root "4.1.2.13 (99%) 4.1.2.- (1%)" "fructose-bisphosphate aldolase (99%) Aldehyde-lyases (1%)" "GO:0006096 (23%) GO:0030388 (22%) GO:0005975 (2.9%)" GO:0016020 (0.1%) "GO:0008270 (26%) GO:0004332 (23%) GO:0016832 (3%)" "glycolytic process (23%) fructose 1,6-bisphosphate metabolic process (22%) carbohydrate metabolic process (2.9%)" membrane (0.1%) "zinc ion binding (26%) fructose-bisphosphate aldolase activity (23%) aldehyde-lyase activity (3%)" "IPR000771 (26%) IPR013785 (26%) IPR050246 (25.9%)" "Fructose-bisphosphate aldolase, class-II (26%) Aldolase-type TIM barrel (26%) Class II Fructose-bisphosphate Aldolase (25.9%)" DLGEAQAEVVHSLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (23.8%) GO:0006529 (1.2%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (23.8%) GO:0000166 (1.2%)" "L-asparagine biosynthetic process (23.8%) obsolete asparagine biosynthetic process (1.2%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (23.8%) nucleotide binding (1.2%)" "IPR004618 (34.4%) IPR006195 (32.8%) IPR045864 (32.8%)" "Aspartate--ammonia ligase (34.4%) Aminoacyl-tRNA synthetase, class II (32.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (32.8%)" VHYLNLVTGVNPENPYEVELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25.9%) IPR035376 (25.9%) IPR038143 (24.1%)" "NigD-like N-terminal OB domain (25.9%) NigD-like, C-terminal domain (25.9%) NigD-like, C-terminal domain superfamily (24.1%)" LELPVDPYEAFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" GPSADFNGSNWNTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.8%) IPR011990 (32.6%) IPR012944 (32.6%)" "SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (32.6%) RagB/SusD domain (32.6%)" LEFTPDHVLLLDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025634 (100%) Protein of unknown function DUF4292 (100%) SEWTSNPYSNYDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" ESGVQFLWQTGK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.4.1.227 (100%) undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (100%) "GO:0005975 (12.1%) GO:0008360 (12.1%) GO:0009252 (12.1%)" GO:0005886 (12.1%) "GO:0050511 (12.1%) GO:0051991 (3.1%)" "carbohydrate metabolic process (12.1%) regulation of cell shape (12.1%) peptidoglycan biosynthetic process (12.1%)" plasma membrane (12.1%) "undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (12.1%) UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity (3.1%)" "IPR004276 (33.3%) IPR006009 (33.3%) IPR007235 (33.3%)" "Glycosyltransferase family 28, N-terminal domain (33.3%) N-acetylglucosaminyltransferase, MurG (33.3%) Glycosyl transferase, family 28, C-terminal (33.3%)" VPFDYNTAGNLWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR035986 (100%) PKD domain superfamily (100%) LPSQAGLGGGSADAAFMLR Pseudomonadati Bacteria Pseudomonadati 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (23.8%) GO:0019288 (23.8%)" "GO:0005524 (26.2%) GO:0050515 (26.2%)" "terpenoid biosynthetic process (23.8%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (23.8%)" "ATP binding (26.2%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (26.2%)" "IPR006204 (17.5%) IPR014721 (17.5%) IPR020568 (17.5%)" "GHMP kinase N-terminal domain (17.5%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17.5%) Ribosomal protein uS5 domain 2-type superfamily (17.5%)" LNLGLNLVSK Bacteria Bacteria 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.8%) GO:0019288 (24.8%)" "GO:0005524 (25.2%) GO:0050515 (25.2%)" "terpenoid biosynthetic process (24.8%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.8%)" "ATP binding (25.2%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.2%)" "IPR006204 (16.9%) IPR004424 (16.6%) IPR013750 (16.6%)" "GHMP kinase N-terminal domain (16.9%) 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (16.6%) GHMP kinase, C-terminal domain (16.6%)" KLDPQASAEALNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR019734 (52%) IPR011990 (48%)" "Tetratricopeptide repeat (52%) Tetratricopeptide-like helical domain superfamily (48%)" LLNQYCEENLLERPEELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.6.2.4 (100%) DNA 3'-5' helicase (100%) "GO:0006260 (8.3%) GO:0006281 (8.3%) GO:0006310 (8.3%)" "GO:0005737 (8.3%) GO:0030894 (8.3%) GO:0043590 (8.3%)" "GO:0003677 (8.3%) GO:0005524 (8.3%) GO:0009378 (8.3%)" "DNA replication (8.3%) DNA repair (8.3%) DNA recombination (8.3%)" "cytoplasm (8.3%) replisome (8.3%) bacterial nucleoid (8.3%)" "DNA binding (8.3%) ATP binding (8.3%) four-way junction helicase activity (8.3%)" "IPR001650 (7.1%) IPR002121 (7.1%) IPR004589 (7.1%)" "Helicase, C-terminal domain-like (7.1%) HRDC domain (7.1%) DNA helicase, ATP-dependent, RecQ type (7.1%)" CLLDEGLR root "2.7.7.8 (89%) 1.-.-.- (6.8%) 1.4.7.1 (1.4%)" "polyribonucleotide nucleotidyltransferase (89%) Oxidoreductases (6.8%) glutamate synthase (ferredoxin) (1.4%)" "GO:0006396 (10.8%) GO:0006402 (10.8%) GO:0010038 (0.4%)" "GO:0005829 (10.9%) GO:0016020 (0.9%) GO:0005576 (0.2%)" "GO:0016491 (18.1%) GO:0000175 (10.8%) GO:0003723 (10.8%)" "RNA processing (10.8%) mRNA catabolic process (10.8%) response to metal ion (0.4%)" "cytosol (10.9%) membrane (0.9%) extracellular region (0.2%)" "oxidoreductase activity (18.1%) 3'-5'-RNA exonuclease activity (10.8%) RNA binding (10.8%)" "IPR036188 (7.4%) IPR023753 (7.3%) IPR051691 (7.3%)" "FAD/NAD(P)-binding domain superfamily (7.4%) FAD/NAD(P)-binding domain (7.3%) Metabolic Enzymes: Cyanogenesis, Opine Oxidation, G-3-P Dehydrogenation (7.3%)" GLTFSTPTELCK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005975 (50%) "GO:0003824 (47.4%) GO:0016787 (2.6%)" carbohydrate metabolic process (50%) "catalytic activity (47.4%) hydrolase activity (2.6%)" "IPR004300 (33.3%) IPR011330 (33.3%) IPR052046 (33.3%)" "Glycoside hydrolase family 57, N-terminal domain (33.3%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (33.3%) Glycosyl hydrolase family 57 (33.3%)" VLDTSMGLTPLAGLMMGSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.2.1 (100%) acetate kinase (100%) "GO:0006083 (17%) GO:0006085 (16.3%)" GO:0005737 (16.3%) "GO:0005524 (17%) GO:0008776 (17%) GO:0000287 (16.3%)" "acetate metabolic process (17%) acetyl-CoA biosynthetic process (16.3%)" cytoplasm (16.3%) "ATP binding (17%) acetate kinase activity (17%) magnesium ion binding (16.3%)" "IPR000890 (25.3%) IPR004372 (25.3%) IPR023865 (25.3%)" "Aliphatic acid kinase, short-chain (25.3%) Acetate/propionate kinase (25.3%) Aliphatic acid kinase, short-chain, conserved site (25.3%)" ELFTYGGDYGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.7%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.7%)" "IPR006103 (8%) IPR032312 (8%) IPR050347 (8%)" "Glycoside hydrolase family 2, catalytic domain (8%) Beta-galactosidase, domain 4 (8%) Bacterial Beta-galactosidase (8%)" EVFQNLFFSDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.4%) IPR015712 (8.4%) IPR007645 (8.3%)" "RNA polymerase Rpb2, domain 2 (8.4%) DNA-directed RNA polymerase, subunit 2 (8.4%) RNA polymerase Rpb2, domain 3 (8.3%)" NFTFVLLPLDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) "GO:0005990 (24.4%) GO:0005975 (0.8%)" GO:0009341 (25.2%) "GO:0004565 (25.2%) GO:0030246 (24.4%)" "lactose catabolic process (24.4%) carbohydrate metabolic process (0.8%)" beta-galactosidase complex (25.2%) "beta-galactosidase activity (25.2%) carbohydrate binding (24.4%)" "IPR004199 (7.4%) IPR006102 (7.2%) IPR006103 (7.2%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.2%) Glycoside hydrolase family 2, catalytic domain (7.2%)" NLGYPLMLR Pseudomonadati Bacteria Pseudomonadati "6.3.4.16 (50%) 6.3.5.5 (50%)" "carbamoyl-phosphate synthase (ammonia) (50%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50%)" "GO:0006541 (14.1%) GO:0006526 (13.4%) GO:0006221 (13%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) L-arginine biosynthetic process (13.4%) pyrimidine nucleotide biosynthetic process (13%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.5%) IPR011761 (10.5%) IPR005483 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%) Carbamoyl phosphate synthase, CPSase domain (10.2%)" YALAPGDGALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.2.29 (100%) peptidoglycan lytic transglycosylase (100%) "GO:0009252 (25%) GO:0071555 (25%)" GO:0005886 (25%) GO:0008932 (25%) "peptidoglycan biosynthetic process (25%) cell wall organization (25%)" plasma membrane (25%) lytic endotransglycosylase activity (25%) IPR003770 (100%) Endolytic murein transglycosylase (100%) LLDGFGGLSDALDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (17%) IPR004634 (17%) IPR004635 (17%)" "Peptidase S49 (17%) Peptidase S49, protease IV (17%) Peptidase S49, SppA (17%)" MLTFPCAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.7%) GO:0019288 (24.7%)" "GO:0005524 (25.3%) GO:0050515 (25.3%)" "terpenoid biosynthetic process (24.7%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.7%)" "ATP binding (25.3%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.3%)" "IPR006204 (16.9%) IPR014721 (16.9%) IPR020568 (16.9%)" "GHMP kinase N-terminal domain (16.9%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (16.9%) Ribosomal protein uS5 domain 2-type superfamily (16.9%)" TQFDVPFVCGAK Bacteria Bacteria 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (22.4%) GO:0016843 (2.6%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (22.4%) amine-lyase activity (2.6%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" LLAMGLSAEQVAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) GGRPELFSTLTMENLSLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.7%) IPR011659 (14.7%) IPR012393 (14.7%)" "Tail specific protease (14.7%) WD40-like beta-propeller (14.7%) Tricorn protease (14.7%)" LPTENFTATAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.5%) IPR041542 (20.5%) IPR051795 (20.5%)" "Glycoside hydrolase, family 43 (20.5%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.5%) Glycosyl Hydrolase Family 43 (20.5%)" TLDYLNQLLNDPELCKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006261 (12.5%) GO:0006265 (12.5%)" "GO:0005694 (12.5%) GO:0005737 (12.5%) GO:0009330 (12.5%)" "GO:0003677 (12.5%) GO:0005524 (12.5%) GO:0034335 (12.5%)" "DNA-templated DNA replication (12.5%) DNA topological change (12.5%)" "chromosome (12.5%) cytoplasm (12.5%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.5%)" "DNA binding (12.5%) ATP binding (12.5%) DNA negative supercoiling activity (12.5%)" "IPR002205 (12.8%) IPR005743 (12.8%) IPR006691 (12.8%)" "DNA topoisomerase, type IIA, domain A (12.8%) DNA gyrase, subunit A (12.8%) DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat (12.8%)" EDVTNLLLNLK Bacteria Bacteria 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) "GO:0000428 (16.7%) GO:0005737 (16.6%)" "GO:0003899 (16.7%) GO:0046983 (16.7%) GO:0003677 (16.6%)" DNA-templated transcription (16.7%) "DNA-directed RNA polymerase complex (16.7%) cytoplasm (16.6%)" "DNA-directed RNA polymerase activity (16.7%) protein dimerization activity (16.7%) DNA binding (16.6%)" "IPR011262 (16.7%) IPR011263 (16.7%) IPR036603 (16.7%)" "DNA-directed RNA polymerase, insert domain (16.7%) DNA-directed RNA polymerase, RpoA/D/Rpb3-type (16.7%) RNA polymerase, RBP11-like subunit (16.7%)" EGDLQFLNEVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20.2%) GO:0005737 (19.7%) "GO:0003746 (20.2%) GO:0005525 (20.2%) GO:0003924 (19.7%)" ribosome disassembly (20.2%) cytoplasm (19.7%) "translation elongation factor activity (20.2%) GTP binding (20.2%) GTPase activity (19.7%)" "IPR000640 (6.4%) IPR004161 (6.4%) IPR005517 (6.4%)" "Elongation factor EFG, domain V-like (6.4%) Translation elongation factor EFTu-like, domain 2 (6.4%) Translation elongation factor EFG/EF2, domain IV (6.4%)" NLDHGVNNESLLGLSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (50%) GO:0046873 (50%) membrane (50%) metal ion transmembrane transporter activity (50%) "IPR002523 (25%) IPR045861 (25%) IPR045863 (25%)" "Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB (25%) CorA, cytoplasmic domain (25%) CorA, transmembrane region (25%)" EVLAEWK root "2.7.7.6 (42.9%) 2.7.1.150 (20.4%) 1.2.1.41 (6.1%)" "DNA-directed RNA polymerase (42.9%) 1-phosphatidylinositol-3-phosphate 5-kinase (20.4%) glutamate-5-semialdehyde dehydrogenase (6.1%)" "GO:0006366 (3%) GO:0030007 (1.3%) GO:0036376 (1.3%)" "GO:0005737 (7.1%) GO:0005576 (5.3%) GO:0005665 (3.5%)" "GO:0005524 (5.5%) GO:0003677 (4.8%) GO:0046872 (3.8%)" "transcription by RNA polymerase II (3%) intracellular potassium ion homeostasis (1.3%) sodium ion export across plasma membrane (1.3%)" "cytoplasm (7.1%) extracellular region (5.3%) RNA polymerase II, core complex (3.5%)" "ATP binding (5.5%) DNA binding (4.8%) metal ion binding (3.8%)" "IPR024438 (3.9%) IPR003284 (3%) IPR028994 (2.6%)" "Staygreen protein (3.9%) Salmonella virulence plasmid 65kDa B protein (3%) Integrin alpha, N-terminal (2.6%)" ELSYLHAEGYPAAEMK root 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (13.1%) GO:0006487 (13.1%) GO:0006047 (13.1%)" "GO:0005829 (13.1%) GO:0016020 (0.1%) GO:0005737 (0%)" "GO:0004360 (13.1%) GO:0097367 (13.1%) GO:0016853 (0%)" "fructose 6-phosphate metabolic process (13.1%) protein N-linked glycosylation (13.1%) UDP-N-acetylglucosamine metabolic process (13.1%)" "cytosol (13.1%) membrane (0.1%) cytoplasm (0%)" "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (13.1%) carbohydrate derivative binding (13.1%) isomerase activity (0%)" "IPR001347 (12.8%) IPR035490 (12.8%) IPR046348 (12.8%)" "SIS domain (12.8%) GlmS/FrlB, SIS domain 2 (12.8%) SIS domain superfamily (12.8%)" WTGEGTSNKYPLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LTPFTTNKPGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) "IPR021280 (50%) IPR052724 (50%)" "Protein O-mannosyl-transferase TMEM260-like (50%) Glycosyltransferase 117 domain-containing protein (50%)" TYSELLGNLER Bacteria Bacteria 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.4%) GO:0006002 (14.1%)" GO:0005829 (14.4%) "GO:0003872 (14.4%) GO:0046872 (14.4%) GO:0005524 (14.2%)" "response to glucose (14.4%) fructose 6-phosphate metabolic process (14.1%)" cytosol (14.4%) "6-phosphofructokinase activity (14.4%) metal ion binding (14.4%) ATP binding (14.2%)" "IPR000023 (25.3%) IPR011183 (24.9%) IPR035966 (24.9%)" "Phosphofructokinase domain (25.3%) Pyrophosphate-dependent phosphofructokinase PfpB (24.9%) Phosphofructokinase superfamily (24.9%)" LTAALGDR root "4.2.1.11 (80.2%) 4.2.1.59 (6.5%) 2.1.1.334 (2.2%)" "phosphopyruvate hydratase (80.2%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (6.5%) methanethiol S-methyltransferase (2.2%)" "GO:0006096 (11.7%) GO:0006633 (1.1%) GO:0009245 (1.1%)" "GO:0005576 (12.4%) GO:0000015 (11.7%) GO:0009986 (11.4%)" "GO:0000287 (11.8%) GO:0004634 (11.7%) GO:0005524 (1.1%)" "glycolytic process (11.7%) fatty acid biosynthetic process (1.1%) lipid A biosynthetic process (1.1%)" "extracellular region (12.4%) phosphopyruvate hydratase complex (11.7%) cell surface (11.4%)" "magnesium ion binding (11.8%) phosphopyruvate hydratase activity (11.7%) ATP binding (1.1%)" "IPR000941 (11.5%) IPR020810 (11.5%) IPR036849 (11.5%)" "Enolase (11.5%) Enolase, C-terminal TIM barrel domain (11.5%) Enolase-like, C-terminal domain superfamily (11.5%)" LMAEGYGFGAEGDWK Bacteria Bacteria 5.3.1.4 (100%) L-arabinose isomerase (100%) GO:0019569 (25.1%) GO:0005829 (25.1%) "GO:0008733 (25.1%) GO:0030145 (23.9%) GO:0046872 (0.8%)" L-arabinose catabolic process to D-xylulose 5-phosphate (25.1%) cytosol (25.1%) "L-arabinose isomerase activity (25.1%) manganese ion binding (23.9%) metal ion binding (0.8%)" "IPR003762 (14.3%) IPR055390 (14.3%) IPR009015 (14.3%)" "L-arabinose isomerase (14.3%) L-arabinose isomerase, central domain (14.3%) L-fucose isomerase, N-terminal/central domain superfamily (14.3%)" KGWLTPEQAEEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (47.5%) GO:0003746 (52.5%) cytoplasm (47.5%) translation elongation factor activity (52.5%) "IPR014039 (20.6%) IPR036402 (20.6%) IPR001816 (19.6%)" "Translation elongation factor EFTs/EF1B, dimerisation (20.6%) Elongation factor Ts, dimerisation domain superfamily (20.6%) Translation elongation factor EFTs/EF1B (19.6%)" GLTSSASDMLVGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0044718 (8.3%) GO:0009279 (83.3%) GO:0015344 (8.3%) siderophore transmembrane transport (8.3%) cell outer membrane (83.3%) siderophore uptake transmembrane transporter activity (8.3%) "IPR012910 (13.3%) IPR039426 (13.3%) IPR008969 (12.7%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent receptor-like (13.3%) Carboxypeptidase-like, regulatory domain superfamily (12.7%)" LDNLLDLTAK Bacteria Bacteria 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.7%) GO:0009265 (16.7%)" GO:0031250 (16.7%) "GO:0004748 (16.7%) GO:0005524 (16.7%) GO:0008998 (16.7%)" "DNA replication (16.7%) 2'-deoxyribonucleotide biosynthetic process (16.7%)" anaerobic ribonucleoside-triphosphate reductase complex (16.7%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.7%) ATP binding (16.7%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.7%)" "IPR005144 (50%) IPR012833 (50%)" "ATP-cone domain (50%) Ribonucleoside-triphosphate reductase, anaerobic (50%)" LAQLGVDSFEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.5.1.2 (50.8%) 4.3.3.6 (49.2%)" "glutaminase (50.8%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (49.2%)" "GO:0008614 (14.2%) GO:0042823 (14.2%) GO:0006543 (13.8%)" "GO:0005829 (14.2%) GO:1903600 (14.2%)" "GO:0004359 (14.2%) GO:0036381 (13.8%) GO:0016740 (0.9%)" "pyridoxine metabolic process (14.2%) pyridoxal phosphate biosynthetic process (14.2%) L-glutamine catabolic process (13.8%)" "cytosol (14.2%) glutaminase complex (14.2%)" "glutaminase activity (14.2%) pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (13.8%) transferase activity (0.9%)" "IPR002161 (33.7%) IPR021196 (33.7%) IPR029062 (32.6%)" "Pyridoxal 5'-phosphate synthase subunit PdxT/SNO (33.7%) PdxT/SNO family, conserved site (33.7%) Class I glutamine amidotransferase-like (32.6%)" LVLGTLFR root "2.4.2.9 (57.1%) 3.6.4.13 (34.3%) 2.4.-.- (2.9%)" "uracil phosphoribosyltransferase (57.1%) RNA helicase (34.3%) Glycosyltransferases (2.9%)" "GO:0000271 (10.2%) GO:0033214 (3.6%) GO:0006310 (0.9%)" "GO:0005886 (15.9%) GO:0016020 (10%) GO:1990904 (1.5%)" "GO:0005524 (8.3%) GO:0140359 (6.3%) GO:0016887 (5.9%)" "polysaccharide biosynthetic process (10.2%) siderophore-iron import into cell (3.6%) DNA recombination (0.9%)" "plasma membrane (15.9%) membrane (10%) ribonucleoprotein complex (1.5%)" "ATP binding (8.3%) ABC-type transporter activity (6.3%) ATP hydrolysis activity (5.9%)" "IPR007267 (7.5%) IPR051401 (7.5%) IPR027417 (6.1%)" "GtrA/DPMS, transmembrane domain (7.5%) Bacterial Cell Wall Glycosylation GtrA (7.5%) P-loop containing nucleoside triphosphate hydrolase (6.1%)" LVPHTCNEVDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.9%) IPR033985 (34.9%) IPR011990 (30.2%)" "RagB/SusD domain (34.9%) SusD-like, N-terminal (34.9%) Tetratricopeptide-like helical domain superfamily (30.2%)" TLGLLTSGGDAPGMNAALR Bacteria Bacteria 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" "GO:0005945 (9.1%) GO:0016020 (0.1%)" "GO:0003872 (9.1%) GO:0046872 (9.1%) GO:0005524 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" "6-phosphofructokinase complex (9.1%) membrane (0.1%)" "6-phosphofructokinase activity (9.1%) metal ion binding (9.1%) ATP binding (9.1%)" "IPR000023 (17.2%) IPR035966 (17.1%) IPR012828 (17%)" "Phosphofructokinase domain (17.2%) Phosphofructokinase superfamily (17.1%) ATP-dependent 6-phosphofructokinase, prokaryotic (17%)" STGFKEPAEEVLSDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027823 (100%) Domain of unknown function DUF4468 with TBP-like fold (100%) VLCVSSYGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20.2%) GO:0006189 (19.3%) GO:0006164 (0.9%)" "GO:0004637 (20.2%) GO:0005524 (20.2%) GO:0046872 (19.3%)" "purine nucleobase biosynthetic process (20.2%) 'de novo' IMP biosynthetic process (19.3%) purine nucleotide biosynthetic process (0.9%)" "phosphoribosylamine-glycine ligase activity (20.2%) ATP binding (20.2%) metal ion binding (19.3%)" "IPR000115 (11.6%) IPR020560 (11.6%) IPR011054 (11.1%)" "Phosphoribosylglycinamide synthetase (11.6%) Phosphoribosylglycinamide synthetase, C-domain (11.6%) Rudiment single hybrid motif (11.1%)" YLGGLCVPGCADYSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.12 (100%) aspartate--tRNA ligase (100%) GO:0006422 (20%) GO:0005737 (20%) "GO:0003676 (20%) GO:0004815 (20%) GO:0005524 (20%)" aspartyl-tRNA aminoacylation (20%) cytoplasm (20%) "nucleic acid binding (20%) aspartate-tRNA ligase activity (20%) ATP binding (20%)" "IPR004364 (9.2%) IPR004365 (9.2%) IPR004524 (9.2%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (9.2%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (9.2%) Aspartate-tRNA ligase, type 1 (9.2%)" SETNPDVLYVDDVEMVYNADVKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024311 (34.6%) IPR038653 (34.6%) IPR025112 (30.8%)" "Lipocalin-like domain (34.6%) Putative carbohydrate metabolism domain superfamily (34.6%) Putative carbohydrate metabolism domain (30.8%)" FCQAFMTELYR root "1.4.1.4 (88.4%) 1.4.1.2 (11.6%)" "glutamate dehydrogenase (NADP(+)) (88.4%) glutamate dehydrogenase (11.6%)" "GO:0006537 (24.2%) GO:0006520 (0.1%) GO:0019552 (0.1%)" "GO:0005829 (24.2%) GO:0016020 (0.1%)" "GO:0004354 (24.2%) GO:0000166 (22.4%) GO:0004352 (4.7%)" "glutamate biosynthetic process (24.2%) amino acid metabolic process (0.1%) L-glutamate catabolic process via 2-hydroxyglutarate (0.1%)" "cytosol (24.2%) membrane (0.1%)" "glutamate dehydrogenase (NADP+) activity (24.2%) nucleotide binding (22.4%) glutamate dehydrogenase (NAD+) activity (4.7%)" "IPR006097 (11.5%) IPR046346 (11.5%) IPR050724 (11.5%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.5%) Aminoacid dehydrogenase-like, N-terminal domain superfamily (11.5%) Glutamate/Leucine/Phenylalanine/Valine dehydrogenases (11.5%)" ANLLVATTPMEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016740 (100%) transferase activity (100%) DYDVLVEGNTDNVPVSTTSAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) "IPR006665 (34.4%) IPR050330 (34.4%) IPR036737 (31.3%)" "OmpA-like domain (34.4%) Bacterial Outer Membrane Structural/Functional (34.4%) OmpA-like domain superfamily (31.3%)" LPFNLTLR root "6.2.1.64 (91.7%) 2.4.-.- (4.2%) 2.7.13.3 (4.2%)" "E1 NEDD8-activating enzyme (91.7%) Glycosyltransferases (4.2%) histidine kinase (4.2%)" "GO:0045116 (12.4%) GO:0042773 (3.1%) GO:0044718 (2.6%)" "GO:0005634 (11.9%) GO:0005737 (10.9%) GO:0016020 (4.1%)" "GO:0019781 (12.4%) GO:0005524 (11.9%) GO:0004129 (3.1%)" "protein neddylation (12.4%) ATP synthesis coupled electron transport (3.1%) siderophore transmembrane transport (2.6%)" "nucleus (11.9%) cytoplasm (10.9%) membrane (4.1%)" "NEDD8 activating enzyme activity (12.4%) ATP binding (11.9%) cytochrome-c oxidase activity (3.1%)" "IPR014929 (8%) IPR035985 (7.7%) IPR000594 (7.4%)" "E2 binding (8%) Ubiquitin-activating enzyme-like (7.7%) THIF-type NAD/FAD binding fold (7.4%)" LKTPLEYENLLLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (23.6%) GO:0005886 (25.5%) "GO:0015562 (25.5%) GO:0042910 (25.5%)" response to toxic substance (23.6%) plasma membrane (25.5%) "efflux transmembrane transporter activity (25.5%) xenobiotic transmembrane transporter activity (25.5%)" "IPR001036 (34.1%) IPR004764 (34.1%) IPR027463 (31.7%)" "Acriflavin resistance protein (34.1%) Multidrug resistance protein MdtF-like (34.1%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (31.7%)" SLEPAANFPAMFYSAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (34.3%) IPR033985 (34.3%) IPR012944 (31.4%)" "Tetratricopeptide-like helical domain superfamily (34.3%) SusD-like, N-terminal (34.3%) RagB/SusD domain (31.4%)" LVESEFGYHLLQLLDKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0003755 (100%) peptidyl-prolyl cis-trans isomerase activity (100%) "IPR000297 (24.7%) IPR050280 (24.7%) IPR027304 (22.6%)" "Peptidyl-prolyl cis-trans isomerase, PpiC-type (24.7%) Outer Membrane Protein Chaperone SurA (24.7%) Trigger factor/SurA domain superfamily (22.6%)" NNLWNTPYLFNAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.9%) GO:0005737 (48.9%)" GO:0016787 (2.2%) "extracellular region (48.9%) cytoplasm (48.9%)" hydrolase activity (2.2%) "IPR022385 (18.5%) IPR050708 (18.5%) IPR006530 (14.5%)" "Rhs repeat-associated core (18.5%) Type VI secretion system VgrG/RHS (18.5%) YD repeat (14.5%)" EGDAFCYLQAPWGEFETLPAALGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (21.4%) IPR003379 (21.4%) IPR055268 (21.4%)" "Pyruvate carboxyltransferase (21.4%) Carboxylase, conserved domain (21.4%) Pyruvate carboxylase-like (21.4%)" LFYDTVK root "1.3.5.1 (98.2%) 1.3.5.4 (1.5%) 2.7.7.48 (0.2%)" "succinate dehydrogenase (98.2%) Transferred entry: 1.3.5.1 (1.5%) RNA-directed RNA polymerase (0.2%)" "GO:0009061 (17.9%) GO:0006351 (0%) GO:0039694 (0%)" "GO:0005886 (18%) GO:0016020 (0%) GO:0005829 (0%)" "GO:0009055 (17.9%) GO:0050660 (17.9%) GO:0000104 (14%)" "anaerobic respiration (17.9%) DNA-templated transcription (0%) viral RNA genome replication (0%)" "plasma membrane (18%) membrane (0%) cytosol (0%)" "electron transfer activity (17.9%) flavin adenine dinucleotide binding (17.9%) succinate dehydrogenase activity (14%)" "IPR003953 (14.3%) IPR030664 (14.3%) IPR036188 (14.3%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.3%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.3%) FAD/NAD(P)-binding domain superfamily (14.3%)" TPEGYPCGSMGPTTANR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.9%) "GO:0046872 (24.9%) GO:0051539 (24.9%) GO:0004333 (23.9%)" tricarboxylic acid cycle (24.9%) "metal ion binding (24.9%) 4 iron, 4 sulfur cluster binding (24.9%) fumarate hydratase activity (23.9%)" "IPR004647 (19.7%) IPR051208 (19.7%) IPR004646 (19.3%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (19.7%) Class-I Fumarase/Tartrate Dehydratase (19.7%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (19.3%)" NQVDVLNGLSESDGVAHYLNSSLNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.6.2.4 (100%) DNA 3'-5' helicase (100%) "GO:0006281 (8.6%) GO:0006310 (8.6%) GO:0006260 (7.4%)" "GO:0005737 (8.6%) GO:0030894 (8.6%) GO:0043590 (8.6%)" "GO:0005524 (8.6%) GO:0009378 (8.6%) GO:0043138 (8.6%)" "DNA repair (8.6%) DNA recombination (8.6%) DNA replication (7.4%)" "cytoplasm (8.6%) replisome (8.6%) bacterial nucleoid (8.6%)" "ATP binding (8.6%) four-way junction helicase activity (8.6%) 3'-5' DNA helicase activity (8.6%)" "IPR011545 (8.2%) IPR014001 (8.2%) IPR004589 (7.6%)" "DEAD/DEAH-box helicase domain (8.2%) Helicase superfamily 1/2, ATP-binding domain (8.2%) DNA helicase, ATP-dependent, RecQ type (7.6%)" VKVNNEEVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006412 (16.7%) GO:0042254 (16.7%)" "GO:0005737 (16.7%) GO:0015935 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" "translation (16.7%) ribosome biogenesis (16.7%)" "cytoplasm (16.7%) small ribosomal subunit (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR000851 (14.9%) IPR005324 (14.9%) IPR005712 (14.9%)" "Small ribosomal subunit protein uS5 (14.9%) Small ribosomal subunit protein uS5, C-terminal (14.9%) Small ribosomal subunit protein uS5, bacteria (14.9%)" SGLAFVDNPAHAQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" LFLPVNR root "2.7.11.1 (44.4%) 3.1.2.- (19.4%) 2.7.13.3 (13.9%)" "non-specific serine/threonine protein kinase (44.4%) Thiolester hydrolases (19.4%) histidine kinase (13.9%)" "GO:0016192 (8.5%) GO:0007157 (1.7%) GO:0045197 (1.7%)" "GO:0005886 (14.9%) GO:0016020 (10.8%) GO:0005737 (2%)" "GO:0004930 (5.7%) GO:0005524 (4.9%) GO:0005112 (3%)" "vesicle-mediated transport (8.5%) heterophilic cell-cell adhesion (1.7%) establishment or maintenance of epithelial cell apical/basal polarity (1.7%)" "plasma membrane (14.9%) membrane (10.8%) cytoplasm (2%)" "G protein-coupled receptor activity (5.7%) ATP binding (4.9%) Notch binding (3%)" "IPR000742 (12%) IPR002172 (10.2%) IPR036055 (9.1%)" "EGF-like domain (12%) Low-density lipoprotein (LDL) receptor class A repeat (10.2%) LDL receptor-like superfamily (9.1%)" LNAELEAMR root 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (18.8%) GO:0009099 (18.8%)" "GO:0005737 (2.9%) GO:0005814 (1.4%) GO:0005886 (1.4%)" "GO:0004455 (18.8%) GO:0046872 (18.8%) GO:0016853 (14.5%)" "isoleucine biosynthetic process (18.8%) L-valine biosynthetic process (18.8%)" "cytoplasm (2.9%) centriole (1.4%) plasma membrane (1.4%)" "ketol-acid reductoisomerase activity (18.8%) metal ion binding (18.8%) isomerase activity (14.5%)" "IPR000506 (16.3%) IPR013023 (16.3%) IPR013116 (16.3%)" "Ketol-acid reductoisomerase, C-terminal (16.3%) Ketol-acid reductoisomerase (16.3%) Ketol-acid reductoisomerase, N-terminal (16.3%)" EFHALTGTYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.2.3 (100%) uridine phosphorylase (100%) GO:0006152 (33.3%) GO:0005829 (33.3%) GO:0004731 (33.3%) purine nucleoside catabolic process (33.3%) cytosol (33.3%) purine-nucleoside phosphorylase activity (33.3%) "IPR000845 (52.8%) IPR035994 (47.2%)" "Nucleoside phosphorylase domain (52.8%) Nucleoside phosphorylase superfamily (47.2%)" EVSEQDLLGALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14.1%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14.1%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR001247 (7.9%) IPR012162 (7.9%) IPR015847 (7.9%)" "Exoribonuclease, phosphorolytic domain 1 (7.9%) Polyribonucleotide nucleotidyltransferase (7.9%) Exoribonuclease, phosphorolytic domain 2 (7.9%)" VVFAEGGNPTMLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16%) "GO:0016746 (17.2%) GO:0051287 (17.2%) GO:0004470 (16.6%)" malate metabolic process (16%) "acyltransferase activity (17.2%) NAD binding (17.2%) malic enzyme activity (16.6%)" "IPR002505 (9.5%) IPR012302 (9.5%) IPR051674 (9.5%)" "Phosphate acetyl/butaryl transferase (9.5%) Malic enzyme, NAD-binding (9.5%) Malate Decarboxylating Enzymes (9.5%)" VYKETLAPALQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (16.7%) "GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0000049 (16.7%) GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "ribosome (16.7%) ribonucleoprotein complex (16.7%)" "tRNA binding (16.7%) structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR002132 (20%) IPR020930 (20%) IPR022803 (20%)" "Large ribosomal subunit protein uL5 (20%) Large ribosomal subunit protein uL5, bacteria (20%) Large ribosomal subunit protein uL5 domain superfamily (20%)" LAAGKPYFSVASGGGTGR Bacteria Bacteria IPR025964 (100%) GGGtGRT protein (100%) QWNLAPGTYELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" LSEDELNEFLANNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024302 (34.7%) IPR041662 (34.7%) IPR011990 (30.6%)" "SusD-like (34.7%) SusD-like 2 (34.7%) Tetratricopeptide-like helical domain superfamily (30.6%)" SLYWNDDKDLLDTFVLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006353 (25%) GO:0031564 (25%)" GO:0005829 (25%) GO:0003723 (25%) "DNA-templated transcription termination (25%) transcription antitermination (25%)" cytosol (25%) RNA binding (25%) "IPR006027 (33.3%) IPR011605 (33.3%) IPR035926 (33.3%)" "NusB/RsmB/TIM44 (33.3%) NusB antitermination factor (33.3%) NusB-like superfamily (33.3%)" YMLTASVR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (12.4%) GO:0009279 (87.6%) iron ion transport (12.4%) cell outer membrane (87.6%) "IPR023996 (13.1%) IPR036942 (13.1%) IPR039426 (13%)" "TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.1%) TonB-dependent receptor-like (13%)" AELANTYYQMLYQAHR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015562 (100%) efflux transmembrane transporter activity (100%) "IPR003423 (50%) IPR050737 (50%)" "Outer membrane efflux protein (50%) Unknown (50%)" NSELNLEVPAEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" RLGGATFQVPTELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) GO:0015935 (20%) "GO:0003735 (20%) GO:0019843 (20%) GO:0000049 (19.9%)" translation (20%) small ribosomal subunit (20%) "structural constituent of ribosome (20%) rRNA binding (20%) tRNA binding (19.9%)" "IPR000235 (24.9%) IPR005717 (24.9%) IPR023798 (24.9%)" "Small ribosomal subunit protein uS7 (24.9%) Small ribosomal subunit protein uS7, bacteria/organella (24.9%) Small ribosomal subunit protein uS7 domain (24.9%)" ELRPVVQFGDLYR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.8%) IPR031704 (12.8%) IPR031705 (12.8%)" "Glycoside hydrolase family 36 (12.8%) Glycosyl hydrolase family 36, N-terminal (12.8%) Glycosyl hydrolase family 36, C-terminal (12.8%)" MNQADSMLFTTENFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (33.9%) GO:0140662 (33.9%) GO:0051082 (32.2%)" "ATP binding (33.9%) ATP-dependent protein folding chaperone (33.9%) unfolded protein binding (32.2%)" "IPR013126 (17%) IPR029047 (17%) IPR029048 (17%)" "Heat shock protein 70 family (17%) Heat shock protein 70kD, peptide-binding domain superfamily (17%) Heat shock protein 70kD, C-terminal domain superfamily (17%)" ALFNTSNGLVTAGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016829 (100%) lyase activity (100%) "IPR032149 (72.7%) IPR008160 (27.3%)" "Domain of unknown function DUF4988 (72.7%) Collagen triple helix repeat (27.3%)" SMLESLAR root "2.7.1.150 (55.3%) 1.3.1.9 (32.9%) 2.7.13.3 (3.5%)" "1-phosphatidylinositol-3-phosphate 5-kinase (55.3%) enoyl-[acyl-carrier-protein] reductase (NADH) (32.9%) histidine kinase (3.5%)" "GO:0046854 (8.9%) GO:0006633 (5.2%) GO:0006289 (2.7%)" "GO:0010008 (8.9%) GO:0000329 (8.8%) GO:0005737 (2.9%)" "GO:0005524 (12.2%) GO:0008270 (11.1%) GO:0000285 (8.9%)" "phosphatidylinositol phosphate biosynthetic process (8.9%) fatty acid biosynthetic process (5.2%) nucleotide-excision repair (2.7%)" "endosome membrane (8.9%) fungal-type vacuole membrane (8.8%) cytoplasm (2.9%)" "ATP binding (12.2%) zinc ion binding (11.1%) 1-phosphatidylinositol-3-phosphate 5-kinase activity (8.9%)" "IPR002498 (6%) IPR027483 (6%) IPR027484 (6%)" "Phosphatidylinositol-4-phosphate 4/5-kinase, core (6%) Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily (6%) Phosphatidylinositol-4-phosphate 5-kinase, N-terminal (6%)" VDGLYTADPEKDPTATK root 2.7.4.22 (100%) UMP kinase (100%) "GO:0006225 (19.9%) GO:0044210 (19.9%) GO:0006412 (0.1%)" "GO:0005737 (19.8%) GO:0016020 (0.3%) GO:0005829 (0.1%)" "GO:0005524 (19.9%) GO:0033862 (19.9%) GO:0016301 (0.1%)" "UDP biosynthetic process (19.9%) 'de novo' CTP biosynthetic process (19.9%) translation (0.1%)" "cytoplasm (19.8%) membrane (0.3%) cytosol (0.1%)" "ATP binding (19.9%) UMP kinase activity (19.9%) kinase activity (0.1%)" "IPR001048 (25.1%) IPR015963 (25%) IPR036393 (25%)" "Aspartate/glutamate/uridylate kinase (25.1%) Uridylate kinase, bacteria (25%) Acetylglutamate kinase-like superfamily (25%)" DFDAFWK root "6.1.1.10 (80%) 3.1.1.41 (6.7%) 1.17.4.2 (2.7%)" "methionine--tRNA ligase (80%) cephalosporin-C deacetylase (6.7%) ribonucleoside-triphosphate reductase (thioredoxin) (2.7%)" "GO:0005976 (14.4%) GO:0006431 (9.9%) GO:0000160 (0.2%)" "GO:0005829 (9.9%) GO:0016020 (1.9%) GO:0005634 (0.4%)" "GO:0052689 (14%) GO:0005524 (10.1%) GO:0000049 (9.9%)" "polysaccharide metabolic process (14.4%) methionyl-tRNA aminoacylation (9.9%) phosphorelay signal transduction system (0.2%)" "cytosol (9.9%) membrane (1.9%) nucleus (0.4%)" "carboxylic ester hydrolase activity (14%) ATP binding (10.1%) tRNA binding (9.9%)" "IPR008391 (8.1%) IPR039069 (8.1%) IPR029058 (8%)" "Acetyl xylan esterase domain (8.1%) Carbohydrate esterase 7 family (8.1%) Alpha/Beta hydrolase fold (8%)" VPEASDLKDLNYDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (31.9%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (31.9%)" "IPR001431 (20.3%) IPR007863 (20.3%) IPR011765 (20.3%)" "Peptidase M16, zinc-binding site (20.3%) Peptidase M16, C-terminal (20.3%) Peptidase M16, N-terminal (20.3%)" QPLQLLEAEGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20%) IPR014721 (20%) IPR020568 (20%)" "Small ribosomal subunit protein uS9 (20%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (20%) Ribosomal protein uS5 domain 2-type superfamily (20%)" LNHNVTPLENPSELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001854 (33.3%) IPR018254 (33.3%) IPR036049 (33.3%)" "Large ribosomal subunit protein uL29 (33.3%) Large ribosomal subunit protein uL29, conserved site (33.3%) Large ribosomal subunit protein uL29 superfamily (33.3%)" NFLLPTGK root "2.5.1.17 (50%) 7.1.1.- (50%)" "corrinoid adenosyltransferase (50%) Hydron translocation or charge separation linked to oxidoreductase reactions (50%)" "GO:0006412 (17.5%) GO:0032259 (0.2%) GO:0044718 (0.2%)" "GO:0005840 (17.4%) GO:1990904 (17.4%) GO:0009507 (5.9%)" "GO:0003735 (17.5%) GO:0019843 (17.4%) GO:0003729 (0.4%)" "translation (17.5%) methylation (0.2%) siderophore transmembrane transport (0.2%)" "ribosome (17.4%) ribonucleoprotein complex (17.4%) chloroplast (5.9%)" "structural constituent of ribosome (17.5%) rRNA binding (17.4%) mRNA binding (0.4%)" "IPR020070 (13.9%) IPR020069 (13.8%) IPR020594 (13.8%)" "Large ribosomal subunit protein bL9, N-terminal (13.9%) Large ribosomal subunit protein bL9, C-terminal (13.8%) Large ribosomal subunit protein bL9, bacteria/chloroplast (13.8%)" CQLVGDDLFVTNVK Bacteria Bacteria 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.7%) "GO:0000015 (16.7%) GO:0005576 (16.6%) GO:0009986 (16.6%)" "GO:0000287 (16.7%) GO:0004634 (16.7%)" glycolytic process (16.7%) "phosphopyruvate hydratase complex (16.7%) extracellular region (16.6%) cell surface (16.6%)" "magnesium ion binding (16.7%) phosphopyruvate hydratase activity (16.7%)" "IPR000941 (16.7%) IPR020810 (16.7%) IPR020809 (16.7%)" "Enolase (16.7%) Enolase, C-terminal TIM barrel domain (16.7%) Enolase, conserved site (16.7%)" HYELPTMEGGFEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) VFAGNTGVELAPTAEDVAGFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (49.1%) GO:0016301 (50.9%) carbohydrate metabolic process (49.1%) kinase activity (50.9%) "IPR018484 (25%) IPR018485 (25%) IPR043129 (25%)" "Carbohydrate kinase FGGY, N-terminal (25%) Carbohydrate kinase FGGY, C-terminal (25%) ATPase, nucleotide binding domain (25%)" TQEELEELER root 3.4.11.9 (100%) Xaa-Pro aminopeptidase (100%) "GO:0006508 (23.9%) GO:0006979 (0.6%)" "GO:0005829 (23.9%) GO:0005783 (0.6%) GO:0005794 (0.6%)" "GO:0030145 (23.9%) GO:0070006 (23.9%) GO:0003677 (0.6%)" "proteolysis (23.9%) response to oxidative stress (0.6%)" "cytosol (23.9%) endoplasmic reticulum (0.6%) Golgi apparatus (0.6%)" "manganese ion binding (23.9%) metalloaminopeptidase activity (23.9%) DNA binding (0.6%)" "IPR000994 (19.6%) IPR007865 (19.6%) IPR052433 (19.6%)" "Peptidase M24 (19.6%) Aminopeptidase P, N-terminal (19.6%) Xaa-Pro dipeptidase-like (19.6%)" SLGQFNLTGLAPAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0005524 (33.6%) GO:0140662 (33.6%) GO:0051082 (32.7%)" "ATP binding (33.6%) ATP-dependent protein folding chaperone (33.6%) unfolded protein binding (32.7%)" "IPR013126 (16.8%) IPR029047 (16.8%) IPR029048 (16.8%)" "Heat shock protein 70 family (16.8%) Heat shock protein 70kD, peptide-binding domain superfamily (16.8%) Heat shock protein 70kD, C-terminal domain superfamily (16.8%)" LALVSPFKDADQWDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" YDYSAFVK Bacteria Bacteria GO:0009279 (50%) GO:0015344 (50%) cell outer membrane (50%) siderophore uptake transmembrane transporter activity (50%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR039426 (20.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) TonB-dependent receptor-like (20.5%)" LVYEGDKFGYDYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) KLLAEGEAGDNVGLLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.3%) GO:0032045 (14.3%)" "GO:0000287 (14.3%) GO:0003746 (14.3%) GO:0003924 (14.3%)" "cytosol (14.3%) guanyl-nucleotide exchange factor complex (14.3%)" "magnesium ion binding (14.3%) translation elongation factor activity (14.3%) GTPase activity (14.3%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" AGLTDDDKPLASLLFVGPTGVGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0034605 (25%) GO:0005737 (25%) "GO:0005524 (25%) GO:0016887 (25%)" cellular response to heat (25%) cytoplasm (25%) "ATP binding (25%) ATP hydrolysis activity (25%)" "IPR003593 (10.2%) IPR003959 (10.2%) IPR004176 (10.2%)" "AAA+ ATPase domain (10.2%) ATPase, AAA-type, core (10.2%) Clp, repeat (R) N-terminal domain (10.2%)" TVMVDETVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.7%) GO:0006164 (0.5%)" GO:0005737 (20.2%) "GO:0004642 (20.2%) GO:0005524 (19.7%) GO:0046872 (19.7%)" "'de novo' IMP biosynthetic process (19.7%) purine nucleotide biosynthetic process (0.5%)" cytoplasm (20.2%) "phosphoribosylformylglycinamidine synthase activity (20.2%) ATP binding (19.7%) metal ion binding (19.7%)" "IPR010918 (11.4%) IPR055181 (11.4%) IPR010073 (11.1%)" "PurM-like, C-terminal domain (11.4%) FGAR-AT, PurM N-terminal-like domain (11.4%) Phosphoribosylformylglycinamidine synthase PurL (11.1%)" EMLSFSNQAGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" VPESVMGVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (16.8%) "GO:0005886 (16.5%) GO:0016020 (0.6%)" "GO:0016655 (16.8%) GO:0051537 (16.8%) GO:0046872 (16.5%)" sodium ion transport (16.8%) "plasma membrane (16.5%) membrane (0.6%)" "oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (16.8%) 2 iron, 2 sulfur cluster binding (16.8%) metal ion binding (16.5%)" "IPR001041 (10.1%) IPR001433 (10.1%) IPR008333 (10.1%)" "2Fe-2S ferredoxin-type iron-sulfur binding domain (10.1%) Oxidoreductase FAD/NAD(P)-binding (10.1%) Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain (10.1%)" FVNDFENAVFDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.1.1.- (100%) Hydron translocation or charge separation linked to oxidoreductase reactions (100%) "GO:0016020 (15.7%) GO:0005886 (4.3%)" "GO:0048038 (20%) GO:0051539 (20%) GO:0016651 (15.7%)" "membrane (15.7%) plasma membrane (4.3%)" "quinone binding (20%) 4 iron, 4 sulfur cluster binding (20%) oxidoreductase activity, acting on NAD(P)H (15.7%)" "IPR010226 (33.3%) IPR017896 (33.3%) IPR017900 (33.3%)" "NADH-quinone oxidoreductase, chain I (33.3%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (33.3%) 4Fe-4S ferredoxin, iron-sulphur binding, conserved site (33.3%)" LEDAPWPATKEELLDYATR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales IPR021527 (100%) Protein of unknown function DUF2795 (100%) TQLLETGVEELVNAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.8%) GO:0004356 (51.2%) glutamine biosynthetic process (48.8%) glutamine synthetase activity (51.2%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" FLEGNNLFSDLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" DLTDSTVLR root "4.3.2.2 (99.9%) 3.1.3.37 (0%) 1.10.3.2 (0%)" "adenylosuccinate lyase (99.9%) sedoheptulose-bisphosphatase (0%) laccase (0%)" "GO:0006189 (19.9%) GO:0044208 (19.9%) GO:0006188 (5.3%)" "GO:0005829 (15.1%) GO:0005634 (0%) GO:0009507 (0%)" "GO:0004018 (25.1%) GO:0070626 (13.8%) GO:0016829 (0.2%)" "'de novo' IMP biosynthetic process (19.9%) 'de novo' AMP biosynthetic process (19.9%) IMP biosynthetic process (5.3%)" "cytosol (15.1%) nucleus (0%) chloroplast (0%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (25.1%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (13.8%) lyase activity (0.2%)" "IPR047136 (12.6%) IPR013539 (12.6%) IPR008948 (12.6%)" "Adenylosuccinate lyase PurB, bacteria (12.6%) Adenylosuccinate lyase PurB, C-terminal (12.6%) L-Aspartase-like (12.6%)" AAGVQLLNSGGPGEAADLR Pseudomonadati Bacteria Pseudomonadati GO:0044718 (6.3%) GO:0009279 (87.5%) GO:0015344 (6.3%) siderophore transmembrane transport (6.3%) cell outer membrane (87.5%) siderophore uptake transmembrane transporter activity (6.3%) "IPR012910 (14.6%) IPR037066 (14.6%) IPR039426 (14.6%)" "TonB-dependent receptor, plug domain (14.6%) TonB-dependent receptor, plug domain superfamily (14.6%) TonB-dependent receptor-like (14.6%)" NNNLPFSR root "GO:0006281 (23.9%) GO:0006310 (23.9%)" "GO:0005634 (1.4%) GO:0016020 (0.5%)" "GO:0003676 (23.9%) GO:0008409 (23.9%) GO:0004674 (1.4%)" "DNA repair (23.9%) DNA recombination (23.9%)" "nucleus (1.4%) membrane (0.5%)" "nucleic acid binding (23.9%) 5'-3' exonuclease activity (23.9%) protein serine/threonine kinase activity (1.4%)" "IPR001667 (16.1%) IPR003156 (16.1%) IPR004610 (16.1%)" "DDH domain (16.1%) DHHA1 domain (16.1%) Bacterial RecJ exonuclease (16.1%)" GGTNALLEYFGEGLDSLSTTGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.1%) GO:0005829 (20.1%) "GO:0003994 (20.1%) GO:0051539 (20.1%) GO:0046872 (19.5%)" tricarboxylic acid cycle (20.1%) cytosol (20.1%) "aconitate hydratase activity (20.1%) 4 iron, 4 sulfur cluster binding (20.1%) metal ion binding (19.5%)" "IPR001030 (11.4%) IPR050926 (11.4%) IPR000573 (11.1%)" "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.4%) Aconitase/IPM Isomerase (11.4%) Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.1%)" SSLEALDADGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.5%) IPR013148 (14.5%) IPR013189 (14.5%)" "Glycoside hydrolase, family 32 (14.5%) Glycosyl hydrolase family 32, N-terminal (14.5%) Glycosyl hydrolase family 32, C-terminal (14.5%)" NPGNFLVR root "7.-.-.- (97.8%) 2.7.11.1 (2.2%)" "Translocases (97.8%) non-specific serine/threonine protein kinase (2.2%)" "GO:0022900 (19.1%) GO:0005975 (0.9%) GO:0031179 (0.9%)" "GO:0005886 (19.1%) GO:0016020 (0.9%)" "GO:0009055 (19.1%) GO:0046872 (19.1%) GO:0051539 (19.1%)" "electron transport chain (19.1%) carbohydrate metabolic process (0.9%) peptide modification (0.9%)" "plasma membrane (19.1%) membrane (0.9%)" "electron transfer activity (19.1%) metal ion binding (19.1%) 4 iron, 4 sulfur cluster binding (19.1%)" "IPR010208 (13.9%) IPR011538 (13.9%) IPR017896 (13.9%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (13.9%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (13.9%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (13.9%)" RADNYSQWYNDLVVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%)" "GO:0004827 (20%) GO:0005524 (20%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%)" "proline-tRNA ligase activity (20%) ATP binding (20%)" "IPR004499 (11.5%) IPR002314 (11.1%) IPR004154 (11.1%)" "Proline-tRNA ligase, class IIa, archaeal-type (11.5%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%) Anticodon-binding (11.1%)" GFTTVLCPDGEVGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (20%) IPR001867 (20%) IPR011006 (20%)" "Signal transduction response regulator, receiver domain (20%) OmpR/PhoB-type DNA-binding domain (20%) CheY-like superfamily (20%)" DGRDFEMWQYTGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.17 (100%) lysozyme (100%) "GO:0009253 (25%) GO:0016052 (25%) GO:0016998 (25%)" GO:0003796 (25%) "peptidoglycan catabolic process (25%) carbohydrate catabolic process (25%) cell wall macromolecule catabolic process (25%)" lysozyme activity (25%) "IPR002053 (47.4%) IPR017853 (43.9%) IPR018077 (8.8%)" "Glycoside hydrolase, family 25 (47.4%) Glycoside hydrolase superfamily (43.9%) Glycoside hydrolase, family 25 subgroup (8.8%)" LMALGYLGK root GO:0009279 (99.4%) GO:0016491 (0.6%) cell outer membrane (99.4%) oxidoreductase activity (0.6%) "IPR033985 (33.6%) IPR011990 (33%) IPR012944 (33%)" "SusD-like, N-terminal (33.6%) Tetratricopeptide-like helical domain superfamily (33%) RagB/SusD domain (33%)" LDEAAEALKTLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (33.3%) GO:0022627 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic small ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001865 (25%) IPR005706 (25%) IPR018130 (25%)" "Small ribosomal subunit protein uS2 (25%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25%) Small ribosomal subunit protein uS2, conserved site (25%)" TTTPSESYLVSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DSFEEYRQQEQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.3%) GO:0009099 (14.3%)" GO:0005948 (14.3%) "GO:0000287 (14.3%) GO:0003984 (14.3%) GO:0030976 (14.3%)" "isoleucine biosynthetic process (14.3%) L-valine biosynthetic process (14.3%)" acetolactate synthase complex (14.3%) "magnesium ion binding (14.3%) acetolactate synthase activity (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR012000 (13.5%) IPR029035 (13.5%) IPR045229 (13.5%)" "Thiamine pyrophosphate enzyme, central domain (13.5%) DHS-like NAD/FAD-binding domain superfamily (13.5%) Thiamine pyrophosphate enzyme (13.5%)" LDNVYDTGTWWDKNESSPESLLPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" WNPVEPLSGTSDDDEENSTSTRR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (42.9%) GO:0009279 (57.1%) iron ion transport (42.9%) cell outer membrane (57.1%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VLVLGGGTVGEAAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.5%) GO:0005886 (25.5%) "GO:0000286 (25.5%) GO:0000166 (23.4%)" L-alanine catabolic process (25.5%) plasma membrane (25.5%) "alanine dehydrogenase activity (25.5%) nucleotide binding (23.4%)" "IPR007698 (18.9%) IPR007886 (18.9%) IPR008141 (18.9%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (18.9%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (18.9%) Alanine dehydrogenase (18.9%)" SNPGLLLLK Bacteroidota Bacteria Pseudomonadati Bacteroidota 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0030416 (22.1%) GO:0006094 (8.9%) GO:0006096 (8.9%)" "GO:0016020 (22.7%) GO:0005829 (8.9%)" "GO:0004807 (9.3%) GO:0016853 (1.2%) GO:0000155 (0.3%)" "methylamine metabolic process (22.1%) gluconeogenesis (8.9%) glycolytic process (8.9%)" "membrane (22.7%) cytosol (8.9%)" "triose-phosphate isomerase activity (9.3%) isomerase activity (1.2%) phosphorelay sensor kinase activity (0.3%)" "IPR009908 (33.2%) IPR000652 (13.3%) IPR020861 (13.3%)" "Methylamine utilisation protein, MauE (33.2%) Triosephosphate isomerase (13.3%) Triosephosphate isomerase, active site (13.3%)" DNVLLLR root "2.7.11.1 (24.6%) 2.6.1.9 (17.5%) 2.7.7.87 (7.7%)" "non-specific serine/threonine protein kinase (24.6%) histidinol-phosphate transaminase (17.5%) L-threonylcarbamoyladenylate synthase (7.7%)" "GO:0000105 (1.8%) GO:0006811 (1.8%) GO:0032259 (1.1%)" "GO:0016020 (9.6%) GO:0009279 (2.1%) GO:0046930 (1.8%)" "GO:0005524 (4.4%) GO:0015159 (3.3%) GO:0030170 (2.8%)" "L-histidine biosynthetic process (1.8%) monoatomic ion transport (1.8%) methylation (1.1%)" "membrane (9.6%) cell outer membrane (2.1%) pore complex (1.8%)" "ATP binding (4.4%) polysaccharide transmembrane transporter activity (3.3%) pyridoxal phosphate binding (2.8%)" "IPR024425 (4.4%) IPR047793 (4.4%) IPR056066 (4.3%)" "Cell wall-active antibiotics response LiaF-like, C-terminal (4.4%) Cell wall-active antibiotic response protein LiaF, C-terminal domain (4.4%) Domain of unknown function DUF7649 (4.3%)" APQCAGVLHTDFEK root "GO:0005737 (20.2%) GO:0016020 (0.1%)" "GO:0005524 (20.3%) GO:0016887 (20.3%) GO:0005525 (20%)" "cytoplasm (20.2%) membrane (0.1%)" "ATP binding (20.3%) ATP hydrolysis activity (20.3%) GTP binding (20%)" "IPR013029 (10.1%) IPR012675 (10.1%) IPR012676 (10.1%)" "YchF, C-terminal domain (10.1%) Beta-grasp domain superfamily (10.1%) TGS-like (10.1%)" LLTDYKDYDVLVEGNTDNVPVSTTSAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR006665 (34.5%) IPR050330 (34.5%) IPR036737 (31%)" "OmpA-like domain (34.5%) Bacterial Outer Membrane Structural/Functional (34.5%) OmpA-like domain superfamily (31%)" SVFLSPALSYSGWSNMGTHEVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" DLASFDEANSQWK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.21 (100%) beta-glucosidase (100%) GO:0005975 (50%) "GO:0004553 (48.8%) GO:0008422 (1.3%)" carbohydrate metabolic process (50%) "hydrolase activity, hydrolyzing O-glycosyl compounds (48.8%) beta-glucosidase activity (1.3%)" "IPR001764 (12.8%) IPR002772 (12.8%) IPR026891 (12.8%)" "Glycoside hydrolase, family 3, N-terminal (12.8%) Glycoside hydrolase family 3 C-terminal domain (12.8%) Fibronectin type III-like domain (12.8%)" KAAAELGYPVLLR Bacteria Bacteria "6.3.5.5 (93.9%) 5.1.1.7 (3%) 6.3.4.16 (3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (93.9%) diaminopimelate epimerase (3%) carbamoyl-phosphate synthase (ammonia) (3%)" "GO:0006541 (13.9%) GO:0006526 (13.4%) GO:0006221 (13%)" GO:0005737 (13.9%) "GO:0004088 (13.9%) GO:0005524 (13.9%) GO:0046872 (13.9%)" "glutamine metabolic process (13.9%) L-arginine biosynthetic process (13.4%) pyrimidine nucleotide biosynthetic process (13%)" cytoplasm (13.9%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.9%) ATP binding (13.9%) metal ion binding (13.9%)" "IPR005479 (10.4%) IPR005480 (10.4%) IPR011761 (10.4%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.4%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.4%) ATP-grasp fold (10.4%)" TSGQPAPSLTLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" NTDNLSFQYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (3.9%) "GO:0000155 (26.3%) GO:0003700 (26.3%) GO:0043565 (26.3%)" membrane (3.9%) "phosphorelay sensor kinase activity (26.3%) DNA-binding transcription factor activity (26.3%) sequence-specific DNA binding (26.3%)" "IPR011123 (6.9%) IPR001789 (6.7%) IPR003594 (6.7%)" "Two component regulator three Y (6.9%) Signal transduction response regulator, receiver domain (6.7%) Histidine kinase/HSP90-like ATPase domain (6.7%)" ELLLGDR root "7.1.2.2 (94%) 3.6.3.14 (2.8%) 2.3.1.129 (0.6%)" "H(+)-transporting two-sector ATPase (94%) Transferred entry: 7.1.2.2 (2.8%) acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase (0.6%)" "GO:0015986 (0.1%) GO:0072657 (0.1%) GO:0006313 (0.1%)" "GO:0045259 (18.6%) GO:0005886 (10.4%) GO:0005743 (4.1%)" "GO:0005524 (19.2%) GO:0046933 (18.6%) GO:0043531 (18.4%)" "proton motive force-driven ATP synthesis (0.1%) protein localization to membrane (0.1%) DNA transposition (0.1%)" "proton-transporting ATP synthase complex (18.6%) plasma membrane (10.4%) mitochondrial inner membrane (4.1%)" "ATP binding (19.2%) proton-transporting ATP synthase activity, rotational mechanism (18.6%) ADP binding (18.4%)" "IPR027417 (10.2%) IPR005294 (10.2%) IPR000194 (10.2%)" "P-loop containing nucleoside triphosphate hydrolase (10.2%) ATP synthase, F1 complex, alpha subunit (10.2%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.2%)" YQMKPEVDTQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005975 (25%) GO:0005737 (25%) "GO:0004134 (25%) GO:2001070 (25%)" carbohydrate metabolic process (25%) cytoplasm (25%) "4-alpha-glucanotransferase activity (25%) starch binding (25%)" "IPR002044 (20.7%) IPR003385 (20.7%) IPR013783 (19.5%)" "Carbohydrate binding module family 20 (20.7%) Glycoside hydrolase, family 77 (20.7%) Immunoglobulin-like fold (19.5%)" TYLPNYSEFYEK Bacteria Bacteria "6.3.5.1 (98.1%) 6.3.1.5 (1.9%)" "NAD(+) synthase (glutamine-hydrolyzing) (98.1%) NAD(+) synthase (1.9%)" GO:0009435 (16.7%) GO:0005737 (16.7%) "GO:0003952 (16.7%) GO:0004359 (16.7%) GO:0005524 (16.7%)" NAD+ biosynthetic process (16.7%) cytoplasm (16.7%) "NAD+ synthase (glutamine-hydrolyzing) activity (16.7%) glutaminase activity (16.7%) ATP binding (16.7%)" "IPR003010 (14.6%) IPR003694 (14.6%) IPR014445 (14.6%)" "Carbon-nitrogen hydrolase (14.6%) NAD(+) synthetase (14.6%) Glutamine-dependent NAD(+) synthetase (14.6%)" GLETQDMNLFQLLQK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (30.7%) "GO:0005525 (30.7%) GO:0043022 (30.7%) GO:0016787 (8%)" ribosome biogenesis (30.7%) "GTP binding (30.7%) ribosome binding (30.7%) hydrolase activity (8%)" "IPR005225 (14.5%) IPR006073 (14.5%) IPR016484 (14.5%)" "Small GTP-binding domain (14.5%) GTP binding domain (14.5%) GTPase Der (14.5%)" LEWQPDGDVSYCGLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (33.9%) "GO:0004553 (33.9%) GO:0030246 (32.1%)" carbohydrate metabolic process (33.9%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.9%) carbohydrate binding (32.1%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" SFKDFLQLDTPPEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (7.9%) IPR007644 (7.9%) IPR007645 (7.9%)" "RNA polymerase Rpb2, domain 2 (7.9%) RNA polymerase, beta subunit, protrusion (7.9%) RNA polymerase Rpb2, domain 3 (7.9%)" AGGLLGLLNELNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (17.1%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (17.1%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (17.1%) IPR056740 (17.1%) IPR020558 (16.7%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.1%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.1%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.7%)" NLMAFWFDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.2.1.1 (66.7%) 5.4.99.16 (33.3%)" "alpha-amylase (66.7%) maltose alpha-D-glucosyltransferase (33.3%)" "GO:0009313 (48.9%) GO:0005975 (1.1%)" "GO:0004556 (48.9%) GO:0047471 (1.1%)" "oligosaccharide catabolic process (48.9%) carbohydrate metabolic process (1.1%)" "alpha-amylase activity (48.9%) maltose alpha-D-glucosyltransferase activity (1.1%)" "IPR006047 (26.4%) IPR017853 (25.3%) IPR045857 (25.3%)" "Glycosyl hydrolase family 13, catalytic domain (26.4%) Glycoside hydrolase superfamily (25.3%) Oligo-1,6-glucosidase, domain 2 (25.3%)" WMFTDDKGNLVSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.8 (100%) endo-1,4-beta-xylanase (100%) "GO:0000272 (37%) GO:0045493 (13%)" "GO:0004553 (33.3%) GO:0031176 (16.7%)" "polysaccharide catabolic process (37%) xylan catabolic process (13%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) endo-1,4-beta-xylanase activity (16.7%)" "IPR001000 (33.3%) IPR044846 (33.3%) IPR017853 (32.1%)" "Glycoside hydrolase family 10 domain (33.3%) Glycoside hydrolase family 10 (33.3%) Glycoside hydrolase superfamily (32.1%)" LNYNNAENPQPDYWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) MDSGASEYGLLATPYVSLTPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YPWLEWDDNSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (19.6%) GO:0042274 (19.6%)" "GO:0015935 (19.6%) GO:0005840 (1.3%)" "GO:0003735 (19.6%) GO:0019843 (19.6%) GO:0003723 (0.7%)" "translation (19.6%) ribosomal small subunit biogenesis (19.6%)" "small ribosomal subunit (19.6%) ribosome (1.3%)" "structural constituent of ribosome (19.6%) rRNA binding (19.6%) RNA binding (0.7%)" "IPR036986 (17.1%) IPR001912 (16.6%) IPR002942 (16.6%)" "RNA-binding S4 domain superfamily (17.1%) Small ribosomal subunit protein uS4, N-terminal (16.6%) RNA-binding S4 domain (16.6%)" NVDALDGEAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.2.1.1 (100%) NADH:ubiquinone reductase (Na(+)-transporting) (100%) GO:0006814 (50%) GO:0016655 (50%) sodium ion transport (50%) oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (50%) "IPR008703 (20.3%) IPR022615 (20.3%) IPR056147 (20.3%)" "Na(+)-translocating NADH-quinone reductase subunit A (20.3%) Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain (20.3%) NqrA, N-terminal barrel-sandwich hybrid domain (20.3%)" SADDVLMVAEAYLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" EGMSVLEYFLASHGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.9%) GO:0000428 (16.9%) "GO:0003677 (16.9%) GO:0003899 (16.9%) GO:0000287 (15.9%)" DNA-templated transcription (16.9%) DNA-directed RNA polymerase complex (16.9%) "DNA binding (16.9%) DNA-directed RNA polymerase activity (16.9%) magnesium ion binding (15.9%)" "IPR007081 (9.3%) IPR007083 (9.3%) IPR000722 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.3%) RNA polymerase Rpb1, domain 4 (9.3%) RNA polymerase, alpha subunit (9.1%)" VWLGTDAK Bacteria Bacteria "3.4.21.- (69.2%) 3.4.-.- (23.1%) 3.4.21.26 (7.7%)" "Serine endopeptidases (69.2%) Acting on peptide bonds (peptidases) (23.1%) prolyl oligopeptidase (7.7%)" "GO:0006465 (32%) GO:0006508 (1.3%)" "GO:0016020 (27.5%) GO:0005886 (4.6%) GO:0005829 (0.7%)" "GO:0008236 (32%) GO:0004252 (0.7%) GO:0008233 (0.7%)" "signal peptide processing (32%) proteolysis (1.3%)" "membrane (27.5%) plasma membrane (4.6%) cytosol (0.7%)" "serine-type peptidase activity (32%) serine-type endopeptidase activity (0.7%) peptidase activity (0.7%)" "IPR002142 (16.5%) IPR004634 (16.5%) IPR004635 (16.5%)" "Peptidase S49 (16.5%) Peptidase S49, protease IV (16.5%) Peptidase S49, SppA (16.5%)" YKGLTQCNLALEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SGAYSCSTLVDCNTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR024742 (20.3%) IPR010401 (20.1%) IPR032790 (20.1%)" "Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.3%) Glycogen debranching enzyme (20.1%) Glycogen debranching enzyme, C-terminal (20.1%)" GDPMPTPGLPESLNVLLHELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007641 (7.9%) IPR015712 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase Rpb2, domain 7 (7.9%) DNA-directed RNA polymerase, subunit 2 (7.9%)" TGLLPYR root "2.7.11.1 (34.8%) 2.3.1.181 (13%) 2.3.1.- (8.7%)" "non-specific serine/threonine protein kinase (34.8%) lipoyl(octanoyl) transferase (13%) Transferring groups other than amino-acyl groups (8.7%)" "GO:0035556 (3.1%) GO:0000226 (2.9%) GO:0007018 (1%)" "GO:0016020 (5.9%) GO:0005737 (5.2%) GO:0005886 (1.7%)" "GO:0005524 (7.1%) GO:0003676 (5.5%) GO:0046872 (5.2%)" "intracellular signal transduction (3.1%) microtubule cytoskeleton organization (2.9%) microtubule-based movement (1%)" "membrane (5.9%) cytoplasm (5.2%) plasma membrane (1.7%)" "ATP binding (7.1%) nucleic acid binding (5.5%) metal ion binding (5.2%)" "IPR024370 (6.3%) IPR050811 (6.1%) IPR011009 (3.2%)" "PBP domain (6.3%) Phosphate-binding ABC transporter substrate-binding (6.1%) Protein kinase-like domain superfamily (3.2%)" LKDTSWLHPTK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.2.1.20 (50%) 3.2.1.22 (50%)" "alpha-glucosidase (50%) alpha-galactosidase (50%)" "GO:0030246 (53.2%) GO:0016787 (44.3%) GO:0004557 (1.3%)" "carbohydrate binding (53.2%) hydrolase activity (44.3%) alpha-galactosidase activity (1.3%)" "IPR019563 (14.7%) IPR029486 (14.7%) IPR052720 (14.7%)" "Glycosyl-hydrolase 97, catalytic domain (14.7%) Glycosyl-hydrolase 97, N-terminal domain (14.7%) Glycosyl Hydrolase Family 97 (14.7%)" TLLYTLTTEGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR001375 (35%) IPR011042 (32.5%) IPR029058 (32.5%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (35%) Six-bladed beta-propeller, TolB-like (32.5%) Alpha/Beta hydrolase fold (32.5%)" LETSVLDCLGCGNCADVCPGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14.3%)" "GO:0005506 (14.3%) GO:0016903 (14.3%) GO:0030976 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14.3%)" "iron ion binding (14.3%) oxidoreductase activity, acting on the aldehyde or oxo group of donors (14.3%) thiamine pyrophosphate binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" LHDNPDPQKLETLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (24.2%) GO:0004540 (0.8%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (24.2%) RNA nuclease activity (0.8%)" "IPR001900 (12.8%) IPR022966 (12.8%) IPR050180 (12.8%)" "Ribonuclease II/R (12.8%) Ribonuclease II/R, conserved site (12.8%) RNR Ribonuclease (12.8%)" NVPTNPDCLGEAALSNEPALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (19.9%) GO:0019676 (19.9%)" "GO:0046872 (19.9%) GO:0051538 (19.9%) GO:0015930 (14%)" "glutamate biosynthetic process (19.9%) ammonia assimilation cycle (19.9%)" "metal ion binding (19.9%) 3 iron, 4 sulfur cluster binding (19.9%) glutamate synthase activity (14%)" "IPR002489 (12.6%) IPR002932 (12.6%) IPR006982 (12.6%)" "Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase domain (12.6%) Glutamate synthase, central-N (12.6%)" GGQLVDKFVGAASK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045454 (25%) "GO:0005829 (25%) GO:0005737 (12.5%)" GO:0015035 (37.5%) cell redox homeostasis (25%) "cytosol (25%) cytoplasm (12.5%)" protein-disulfide reductase activity (37.5%) "IPR005746 (25.4%) IPR013766 (25.4%) IPR017937 (25.4%)" "Thioredoxin (25.4%) Thioredoxin domain (25.4%) Thioredoxin, conserved site (25.4%)" QVLLTFAR root "6.1.1.20 (98.2%) 3.1.1.11 (1.8%)" "phenylalanine--tRNA ligase (98.2%) pectinesterase (1.8%)" "GO:0006432 (16.1%) GO:0042545 (0.3%) GO:0045490 (0.3%)" "GO:0005737 (16.1%) GO:0016020 (0.8%) GO:0005576 (0.3%)" "GO:0000049 (16.1%) GO:0004826 (16.1%) GO:0005524 (16.1%)" "phenylalanyl-tRNA aminoacylation (16.1%) cell wall modification (0.3%) pectin catabolic process (0.3%)" "cytoplasm (16.1%) membrane (0.8%) extracellular region (0.3%)" "tRNA binding (16.1%) phenylalanine-tRNA ligase activity (16.1%) ATP binding (16.1%)" "IPR002319 (13.9%) IPR006195 (13.9%) IPR045864 (13.9%)" "Phenylalanyl-tRNA synthetase (13.9%) Aminoacyl-tRNA synthetase, class II (13.9%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (13.9%)" MAVANTMR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20.3%) GO:0022627 (20.3%) "GO:0003735 (20.3%) GO:0019843 (20.3%) GO:0003729 (18.6%)" translation (20.3%) cytosolic small ribosomal subunit (20.3%) "structural constituent of ribosome (20.3%) rRNA binding (20.3%) mRNA binding (18.6%)" "IPR001351 (11.1%) IPR004044 (11.1%) IPR004087 (11.1%)" "Small ribosomal subunit protein uS3, C-terminal (11.1%) K Homology domain, type 2 (11.1%) K Homology domain (11.1%)" KLGMTSVFSADGK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000597 (25.1%) IPR009000 (25.1%) IPR019927 (25.1%)" "Large ribosomal subunit protein uL3 (25.1%) Translation protein, beta-barrel domain superfamily (25.1%) Large ribosomal subunit protein uL3, bacteria/organella (25.1%)" KLFVEEGLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0030170 (50%) GO:0008483 (45%) GO:0016740 (5%)" "pyridoxal phosphate binding (50%) transaminase activity (45%) transferase activity (5%)" "IPR001917 (16.8%) IPR004839 (16.8%) IPR015422 (16.8%)" "Aminotransferase, class-II, pyridoxal-phosphate binding site (16.8%) Aminotransferase, class I/classII, large domain (16.8%) Pyridoxal phosphate-dependent transferase, small domain (16.8%)" TDLVEQLDTYFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR025350 (100%) Protein of unknown function DUF4254 (100%) RCGWCDLVQLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" EFSVVDTGGWVVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (32.2%) "GO:0005525 (32.2%) GO:0043022 (32.2%) GO:0016787 (3.4%)" ribosome biogenesis (32.2%) "GTP binding (32.2%) ribosome binding (32.2%) hydrolase activity (3.4%)" "IPR005225 (14.4%) IPR006073 (14.4%) IPR016484 (14.4%)" "Small GTP-binding domain (14.4%) GTP binding domain (14.4%) GTPase Der (14.4%)" GEDKTSALLDLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (48.6%) GO:0004356 (51.4%) glutamine biosynthetic process (48.6%) glutamine synthetase activity (51.4%) "IPR008146 (14.6%) IPR027303 (14.6%) IPR040577 (14.6%)" "Glutamine synthetase, catalytic domain (14.6%) Glutamine synthetase, glycine-rich site (14.6%) Glutamine synthetase, C-terminal (14.6%)" QLKDLQNALNECQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006811 (24.5%) "GO:0009279 (26.4%) GO:0046930 (24.5%)" GO:0015288 (24.5%) monoatomic ion transport (24.5%) "cell outer membrane (26.4%) pore complex (24.5%)" porin activity (24.5%) "IPR006664 (20%) IPR006665 (20%) IPR036737 (20%)" "Outer membrane protein, bacterial (20%) OmpA-like domain (20%) OmpA-like domain superfamily (20%)" LTGNVSDAMGPLLGATVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.4%) IPR012910 (14.4%) IPR023996 (14.4%)" "Carboxypeptidase-like, regulatory domain superfamily (14.4%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" VALAEVTR root "3.4.17.2 (69.2%) 3.1.1.- (15.4%) 2.7.7.7 (7.7%)" "carboxypeptidase B (69.2%) Carboxylic ester hydrolases (15.4%) DNA-directed DNA polymerase (7.7%)" "GO:0006508 (8.3%) GO:0006935 (3.2%) GO:0007165 (3.2%)" "GO:0005615 (8.3%) GO:0005886 (6%) GO:0016020 (3.7%)" "GO:0008270 (9.2%) GO:0004181 (8.3%) GO:0004888 (3.2%)" "proteolysis (8.3%) chemotaxis (3.2%) signal transduction (3.2%)" "extracellular space (8.3%) plasma membrane (6%) membrane (3.7%)" "zinc ion binding (9.2%) metallocarboxypeptidase activity (8.3%) transmembrane signaling receptor activity (3.2%)" "IPR000834 (7.4%) IPR003146 (7.4%) IPR057246 (7%)" "Peptidase M14, carboxypeptidase A (7.4%) Carboxypeptidase, activation peptide (7.4%) Zinc carboxypeptidases, zinc-binding region 1 (7%)" SGDACYLQLDDNTTLLAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25.5%) IPR035376 (25.5%) IPR038143 (24.5%)" "NigD-like N-terminal OB domain (25.5%) NigD-like, C-terminal domain (25.5%) NigD-like, C-terminal domain superfamily (24.5%)" NLPLFSPLNLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) FFEGDPTK root 1.1.1.58 (100%) tagaturonate reductase (100%) "GO:0019592 (21.7%) GO:0031222 (3.3%) GO:0045493 (3.3%)" "GO:0005829 (21.7%) GO:0048046 (3.3%) GO:0005886 (2.2%)" "GO:0008926 (21.7%) GO:0009044 (3.3%) GO:0046556 (3.3%)" "mannitol catabolic process (21.7%) arabinan catabolic process (3.3%) xylan catabolic process (3.3%)" "cytosol (21.7%) apoplast (3.3%) plasma membrane (2.2%)" "mannitol-1-phosphate 5-dehydrogenase activity (21.7%) xylan 1,4-beta-xylosidase activity (3.3%) alpha-L-arabinofuranosidase activity (3.3%)" "IPR013131 (16.9%) IPR013118 (16.1%) IPR036291 (14.4%)" "Mannitol dehydrogenase, N-terminal (16.9%) Mannitol dehydrogenase, C-terminal (16.1%) NAD(P)-binding domain superfamily (14.4%)" VGMTPAGVAEFLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.4.1.1 (100%) alanine dehydrogenase (100%) GO:0042853 (25.6%) GO:0005886 (25.6%) "GO:0000286 (25.6%) GO:0000166 (23.3%)" L-alanine catabolic process (25.6%) plasma membrane (25.6%) "alanine dehydrogenase activity (25.6%) nucleotide binding (23.3%)" "IPR007698 (20.2%) IPR007886 (20.2%) IPR008141 (20.2%)" "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain (20.2%) Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal (20.2%) Alanine dehydrogenase (20.2%)" ALYAETFGNPNSDVTDLDKLAELAHR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.5.1.49 (100%) O-acetylhomoserine aminocarboxypropyltransferase (100%) "GO:0006535 (14.3%) GO:0019346 (14.3%) GO:0071269 (14.3%)" GO:0005737 (14.3%) "GO:0003961 (14.3%) GO:0004124 (14.3%) GO:0030170 (14.3%)" "cysteine biosynthetic process from serine (14.3%) transsulfuration (14.3%) L-homocysteine biosynthetic process (14.3%)" cytoplasm (14.3%) "O-acetylhomoserine aminocarboxypropyltransferase activity (14.3%) cysteine synthase activity (14.3%) pyridoxal phosphate binding (14.3%)" "IPR000277 (17.2%) IPR006235 (17.2%) IPR054542 (17.2%)" "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (17.2%) O-acetylhomoserine/O-acetylserine sulfhydrylase (17.2%) Cys/Met metabolism enzyme, pyridoxal-phosphate attachment site (17.2%)" FTFEVDNVGALR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.5%) IPR013780 (12.5%) IPR013785 (12.5%)" "Glycoside hydrolase family 36 (12.5%) Glycosyl hydrolase, all-beta (12.5%) Aldolase-type TIM barrel (12.5%)" RAGLLHDLGK root "3.1.-.- (99.8%) 3.1.4.- (0.1%) 3.1.4.52 (0.1%)" "Acting on ester bonds (99.8%) Phosphoric diester hydrolases (0.1%) cyclic-guanylate-specific phosphodiesterase (0.1%)" "GO:0006402 (19.9%) GO:0006754 (0%) GO:1902600 (0%)" "GO:0005886 (19.4%) GO:0016020 (0.5%) GO:0005840 (0%)" "GO:0003723 (20.1%) GO:0016787 (19.7%) GO:0004521 (19.6%)" "mRNA catabolic process (19.9%) ATP biosynthetic process (0%) proton transmembrane transport (0%)" "plasma membrane (19.4%) membrane (0.5%) ribosome (0%)" "RNA binding (20.1%) hydrolase activity (19.7%) RNA endonuclease activity (19.6%)" "IPR003607 (12.6%) IPR006675 (12.6%) IPR006674 (12.6%)" "HD/PDEase domain (12.6%) HDIG domain (12.6%) HD domain (12.6%)" TTLQQPTYTEWHDLQVNALNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR006104 (7.4%) IPR050347 (7.4%) IPR004199 (7.2%)" "Glycosyl hydrolases family 2, sugar binding domain (7.4%) Bacterial Beta-galactosidase (7.4%) Beta galactosidase small chain/ domain 5 (7.2%)" FDASSLQK root 3.5.4.4 (100%) adenosine deaminase (100%) "GO:0006154 (1.2%) GO:0006166 (1.2%) GO:0006633 (1.2%)" "GO:0005886 (34.1%) GO:0016020 (2.4%) GO:0005737 (1.2%)" "GO:0003755 (34.1%) GO:0016788 (3.7%) GO:0003959 (1.2%)" "adenosine catabolic process (1.2%) purine ribonucleoside salvage (1.2%) fatty acid biosynthetic process (1.2%)" "plasma membrane (34.1%) membrane (2.4%) cytoplasm (1.2%)" "peptidyl-prolyl cis-trans isomerase activity (34.1%) hydrolase activity, acting on ester bonds (3.7%) NADPH dehydrogenase activity (1.2%)" "IPR052029 (18.2%) IPR027304 (17.5%) IPR046357 (17.5%)" "Periplasmic chaperone PpiD (18.2%) Trigger factor/SurA domain superfamily (17.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (17.5%)" QMANSSLQADQLKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VYFLPVTPFFVTELLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.7%) 6.3.4.16 (49.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.7%) carbamoyl-phosphate synthase (ammonia) (49.3%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" DVEAGQTVEFDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0019843 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) rRNA binding (16.7%)" "IPR001787 (31.3%) IPR028909 (31.3%) IPR036164 (31.3%)" "Large ribosomal subunit protein bL21 (31.3%) Large ribosomal subunit protein bL21-like (31.3%) Large ribosomal subunit protein bL21-like superfamily (31.3%)" SLECVEYPELGMEALWK root "4.2.1.2 (99.6%) 5.3.2.2 (0.4%)" "fumarate hydratase (99.6%) oxaloacetate tautomerase (0.4%)" "GO:0006099 (20.2%) GO:0006106 (0%)" GO:0005829 (0.1%) "GO:0004333 (20.3%) GO:0046872 (20.2%) GO:0051539 (20.2%)" "tricarboxylic acid cycle (20.2%) fumarate metabolic process (0%)" cytosol (0.1%) "fumarate hydratase activity (20.3%) metal ion binding (20.2%) 4 iron, 4 sulfur cluster binding (20.2%)" "IPR004647 (17.1%) IPR051208 (17.1%) IPR036660 (17%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (17.1%) Class-I Fumarase/Tartrate Dehydratase (17.1%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily (17%)" VSVLSAGWDPGSDSLVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.16 (100%) diaminopimelate dehydrogenase (100%) "GO:0009089 (25%) GO:0019877 (25%)" "GO:0000166 (25%) GO:0047850 (25%)" "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" "nucleotide binding (25%) diaminopimelate dehydrogenase activity (25%)" "IPR000683 (25.1%) IPR010190 (25.1%) IPR032094 (25.1%)" "Gfo/Idh/MocA-like oxidoreductase, N-terminal (25.1%) Diaminopimelate dehydrogenase, Ddh (25.1%) Meso-diaminopimelate D-dehydrogenase, C-terminal (25.1%)" RLNYYDHANLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004180 (100%) carboxypeptidase activity (100%) "IPR043741 (51.9%) IPR008969 (48.1%)" "Family of unknown function DUF5686 (51.9%) Carboxypeptidase-like, regulatory domain superfamily (48.1%)" LDEAAEALK root "2.7.1.229 (66.7%) 1.-.-.- (33.3%)" "deoxyribokinase (66.7%) Oxidoreductases (33.3%)" "GO:0006412 (28%) GO:0019303 (0.6%) GO:0044281 (0.6%)" "GO:0022627 (28%) GO:0005886 (0.9%) GO:0005829 (0.6%)" "GO:0003735 (28%) GO:0046872 (0.9%) GO:0004747 (0.6%)" "translation (28%) D-ribose catabolic process (0.6%) small molecule metabolic process (0.6%)" "cytosolic small ribosomal subunit (28%) plasma membrane (0.9%) cytosol (0.6%)" "structural constituent of ribosome (28%) metal ion binding (0.9%) ribokinase activity (0.6%)" "IPR001865 (21.4%) IPR005706 (21.4%) IPR023591 (21.4%)" "Small ribosomal subunit protein uS2 (21.4%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (21.4%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (21.4%)" VFVDEGVTMKR Bacteria Bacteria GO:0006412 (25.1%) GO:0022625 (25.1%) "GO:0003735 (25.1%) GO:0019843 (24.7%)" translation (25.1%) cytosolic large ribosomal subunit (25.1%) "structural constituent of ribosome (25.1%) rRNA binding (24.7%)" "IPR001063 (24.7%) IPR036394 (24.7%) IPR047867 (24.7%)" "Large ribosomal subunit protein uL22 (24.7%) Ribosomal protein uL22 superfamily (24.7%) Large ribosomal subunit protein uL22, bacteria/organella (24.7%)" TLDWSAEGQDGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (58.8%) "GO:0016787 (23.5%) GO:0016829 (17.6%)" carbohydrate metabolic process (58.8%) "hydrolase activity (23.5%) lyase activity (17.6%)" "IPR006047 (25%) IPR013783 (25%) IPR017853 (25%)" "Glycosyl hydrolase family 13, catalytic domain (25%) Immunoglobulin-like fold (25%) Glycoside hydrolase superfamily (25%)" APMEFKPLGNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032812 (100%) SbsA, Ig-like domain (100%) YSPVPGYPDLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "2.6.1.- (95.3%) 2.6.1.1 (4.7%)" "Transaminases (95.3%) aspartate transaminase (4.7%)" GO:0006520 (33.3%) "GO:0030170 (33.3%) GO:0008483 (30.7%) GO:0004069 (2.7%)" amino acid metabolic process (33.3%) "pyridoxal phosphate binding (33.3%) transaminase activity (30.7%) L-aspartate:2-oxoglutarate aminotransferase activity (2.7%)" "IPR004838 (16.7%) IPR004839 (16.7%) IPR015421 (16.7%)" "Aminotransferases, class-I, pyridoxal-phosphate-binding site (16.7%) Aminotransferase, class I/classII, large domain (16.7%) Pyridoxal phosphate-dependent transferase, major domain (16.7%)" DTVGLLAK root "6.3.5.7 (96.7%) 2.7.7.49 (0.8%) 3.1.22.- (0.8%)" "glutaminyl-tRNA synthase (glutamine-hydrolyzing) (96.7%) RNA-directed DNA polymerase (0.8%) Endodeoxyribonucleases producing other than 5'-phosphomonoesters (0.8%)" "GO:0032543 (14.6%) GO:0070681 (14.6%) GO:0007029 (0.2%)" "GO:0005739 (14.6%) GO:0030956 (14.6%) GO:0016020 (1.4%)" "GO:0050567 (14.8%) GO:0005524 (14.2%) GO:0004040 (4.5%)" "mitochondrial translation (14.6%) glutaminyl-tRNAGln biosynthesis via transamidation (14.6%) endoplasmic reticulum organization (0.2%)" "mitochondrion (14.6%) glutamyl-tRNA(Gln) amidotransferase complex (14.6%) membrane (1.4%)" "glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity (14.8%) ATP binding (14.2%) amidase activity (4.5%)" "IPR002912 (14.3%) IPR045865 (14.2%) IPR050990 (14.2%)" "ACT domain (14.3%) ACT-like domain (14.2%) UPF0237/Glycine cleavage system regulator (14.2%)" SFVATDAQLATAGATDVTATK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DRPLEESLALFEK Pseudomonadati Bacteria Pseudomonadati 6.1.1.18 (100%) glutamine--tRNA ligase (100%) "GO:0006425 (24.3%) GO:0006424 (2.6%)" GO:0005829 (24.3%) "GO:0004819 (24.3%) GO:0005524 (24.3%)" "glutaminyl-tRNA aminoacylation (24.3%) glutamyl-tRNA aminoacylation (2.6%)" cytosol (24.3%) "glutamine-tRNA ligase activity (24.3%) ATP binding (24.3%)" "IPR020058 (10.9%) IPR050132 (10.9%) IPR004514 (10.5%)" "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10.9%) Glutamine/Glutamate--tRNA Ligase (10.9%) Glutamine-tRNA synthetase (10.5%)" EVFQNLFFSDKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.4%) IPR015712 (8.4%) IPR007645 (8.3%)" "RNA polymerase Rpb2, domain 2 (8.4%) DNA-directed RNA polymerase, subunit 2 (8.4%) RNA polymerase Rpb2, domain 3 (8.3%)" SNHVTLFVDAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (25.1%) GO:0022625 (25.1%) "GO:0003735 (25.1%) GO:0019843 (24.7%)" translation (25.1%) cytosolic large ribosomal subunit (25.1%) "structural constituent of ribosome (25.1%) rRNA binding (24.7%)" "IPR001063 (25.1%) IPR036394 (25.1%) IPR047867 (25.1%)" "Large ribosomal subunit protein uL22 (25.1%) Ribosomal protein uL22 superfamily (25.1%) Large ribosomal subunit protein uL22, bacteria/organella (25.1%)" EHVLNVMEETTGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.6.5.11 (59.5%) 1.6.5.9 (18.9%) 1.6.99.5 (16.2%)" "Transferred entry: 1.6.5.9 (59.5%) NADH:ubiquinone reductase (non-electrogenic) (18.9%) Transferred entry: 1.6.5.11 (16.2%)" GO:0005886 (25%) "GO:0048038 (25%) GO:0051287 (25%) GO:0008137 (24.8%)" plasma membrane (25%) "quinone binding (25%) NAD binding (25%) NADH dehydrogenase (ubiquinone) activity (24.8%)" "IPR001135 (19.2%) IPR022885 (19.2%) IPR001268 (19%)" "NADH-quinone oxidoreductase, subunit D (19.2%) NAD(P)H-quinone oxidoreductase subunit D/H (19.2%) NADH:ubiquinone oxidoreductase, 30kDa subunit (19%)" GPGMFDLSAFLGKEETLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004818 (16.7%) GO:0005524 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR000924 (10%) IPR001412 (10%) IPR004527 (10%)" "Glutamyl/glutaminyl-tRNA synthetase (10%) Aminoacyl-tRNA synthetase, class I, conserved site (10%) Glutamate-tRNA ligase, bacterial/mitochondrial (10%)" TSYFGNFTYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" NLAVLFK root "2.4.1.227 (62.1%) 3.6.4.12 (15.5%) 2.7.1.71 (6.9%)" "undecaprenyldiphospho-muramoylpentapeptide beta-Nacetylglucosaminyltransferase (62.1%) DNA helicase (15.5%) shikimate kinase (6.9%)" "GO:0008360 (4.1%) GO:0009252 (4.1%) GO:0071555 (4.1%)" "GO:0005886 (10%) GO:0005829 (3.6%) GO:0016020 (3.3%)" "GO:0015661 (4.3%) GO:0050511 (3.8%) GO:0003677 (2.8%)" "regulation of cell shape (4.1%) peptidoglycan biosynthetic process (4.1%) cell wall organization (4.1%)" "plasma membrane (10%) cytosol (3.6%) membrane (3.3%)" "L-lysine efflux transmembrane transporter activity (4.3%) undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity (3.8%) DNA binding (2.8%)" "IPR005642 (4.6%) IPR004276 (3.9%) IPR006009 (3.8%)" "Lysine exporter LysO (4.6%) Glycosyltransferase family 28, N-terminal domain (3.9%) N-acetylglucosaminyltransferase, MurG (3.8%)" LCPALCEK Bacteria Bacteria "1.4.1.13 (61.5%) 1.4.1.14 (21.2%) 1.4.1.- (15.4%)" "glutamate synthase (NADPH) (61.5%) glutamate synthase (NADH) (21.2%) With NAD(+) or NADP(+) as acceptor (15.4%)" GO:0006537 (30.9%) "GO:0051536 (32.2%) GO:0016639 (30.9%) GO:0004355 (3.8%)" glutamate biosynthetic process (30.9%) "iron-sulfur cluster binding (32.2%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (30.9%) glutamate synthase (NADPH) activity (3.8%)" "IPR009051 (16.2%) IPR028261 (16.2%) IPR051394 (16.2%)" "Alpha-helical ferredoxin (16.2%) Dihydroprymidine dehydrogenase domain II (16.2%) Glutamate Synthase (16.2%)" YNMGYGSVNHNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.7%) GO:0009265 (16.7%)" GO:0031250 (16.7%) "GO:0004748 (16.7%) GO:0008998 (16.7%) GO:0005524 (16.4%)" "DNA replication (16.7%) 2'-deoxyribonucleotide biosynthetic process (16.7%)" anaerobic ribonucleoside-triphosphate reductase complex (16.7%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.7%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.7%) ATP binding (16.4%)" "IPR012833 (50.4%) IPR005144 (49.6%)" "Ribonucleoside-triphosphate reductase, anaerobic (50.4%) ATP-cone domain (49.6%)" ADLDYCQCEALTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20.9%) "GO:0022627 (18.6%) GO:0005840 (2.3%) GO:1990904 (2.3%)" "GO:0003735 (20.9%) GO:0019843 (18.6%) GO:0003729 (16.3%)" translation (20.9%) "cytosolic small ribosomal subunit (18.6%) ribosome (2.3%) ribonucleoprotein complex (2.3%)" "structural constituent of ribosome (20.9%) rRNA binding (18.6%) mRNA binding (16.3%)" "IPR001351 (12%) IPR036419 (12%) IPR004044 (10.7%)" "Small ribosomal subunit protein uS3, C-terminal (12%) Ribosomal protein S3, C-terminal domain superfamily (12%) K Homology domain, type 2 (10.7%)" DNEVFTPTDLLNAK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20.9%) GO:0000428 (20.9%) "GO:0003677 (20.9%) GO:0003899 (20.9%) GO:0032549 (16.4%)" DNA-templated transcription (20.9%) DNA-directed RNA polymerase complex (20.9%) "DNA binding (20.9%) DNA-directed RNA polymerase activity (20.9%) ribonucleoside binding (16.4%)" "IPR007645 (10%) IPR007642 (7.9%) IPR015712 (7.9%)" "RNA polymerase Rpb2, domain 3 (10%) RNA polymerase Rpb2, domain 2 (7.9%) DNA-directed RNA polymerase, subunit 2 (7.9%)" AVGLEQELGNMHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.5.5 (100%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (100%) "GO:0006541 (14.3%) GO:0006221 (13.7%) GO:0006526 (13.2%)" GO:0005737 (14.3%) "GO:0004088 (14.3%) GO:0005524 (14.3%) GO:0046872 (14.3%)" "glutamine metabolic process (14.3%) pyrimidine nucleotide biosynthetic process (13.7%) L-arginine biosynthetic process (13.2%)" cytoplasm (14.3%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.3%) ATP binding (14.3%) metal ion binding (14.3%)" "IPR005480 (10.9%) IPR005479 (10.5%) IPR011761 (10.5%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.9%) Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%)" LGLLNWENQFTYQHSSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR025631 (100%) Putative porin-10 (100%) MPSEVQGLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GDLNSPVLVGGAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20.1%) "GO:0005840 (20.1%) GO:1990904 (20.1%)" "GO:0003735 (20.1%) GO:0019843 (18.4%) GO:0003723 (1.4%)" translation (20.1%) "ribosome (20.1%) ribonucleoprotein complex (20.1%)" "structural constituent of ribosome (20.1%) rRNA binding (18.4%) RNA binding (1.4%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" ALAQVSPLPLVLYNVPGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.3.3.7 (100%) 4-hydroxy-tetrahydrodipicolinate synthase (100%) "GO:0009089 (25%) GO:0019877 (25%)" GO:0005829 (25%) GO:0008840 (25%) "lysine biosynthetic process via diaminopimelate (25%) diaminopimelate biosynthetic process (25%)" cytosol (25%) 4-hydroxy-tetrahydrodipicolinate synthase activity (25%) "IPR002220 (25%) IPR005263 (25%) IPR013785 (25%)" "DapA-like (25%) 4-hydroxy-tetrahydrodipicolinate synthase, DapA (25%) Aldolase-type TIM barrel (25%)" SAFLMQQLLQGGMK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.4%) GO:0009252 (11.4%) GO:0071555 (11.4%)" "GO:0030288 (11.4%) GO:0005886 (10.1%) GO:0016020 (1.3%)" "GO:0008658 (11.4%) GO:0008955 (11.4%) GO:0004180 (10.1%)" "regulation of cell shape (11.4%) peptidoglycan biosynthetic process (11.4%) cell wall organization (11.4%)" "outer membrane-bounded periplasmic space (11.4%) plasma membrane (10.1%) membrane (1.3%)" "penicillin binding (11.4%) peptidoglycan glycosyltransferase activity (11.4%) carboxypeptidase activity (10.1%)" "IPR001460 (17.6%) IPR050396 (17.6%) IPR001264 (16.7%)" "Penicillin-binding protein, transpeptidase (17.6%) Glycosyltransferase 51/Transpeptidase (17.6%) Glycosyl transferase, family 51 (16.7%)" VGMNYASCSPFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.7.9.1 (95.1%) 2.7.-.- (4.9%)" "pyruvate, phosphate dikinase (95.1%) Transferring phosphorus-containing groups (4.9%)" "GO:0050242 (25.8%) GO:0005524 (24.5%) GO:0016301 (24.5%)" "pyruvate, phosphate dikinase activity (25.8%) ATP binding (24.5%) kinase activity (24.5%)" "IPR015813 (10.5%) IPR040442 (10.5%) IPR000121 (10.2%)" "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily (10.5%) Pyruvate kinase-like domain superfamily (10.5%) PEP-utilising enzyme, C-terminal (10.2%)" VSDFFVEDGSYFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" LGTTLTPAQLAEFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR000891 (21.2%) IPR003379 (21.2%) IPR055268 (21.2%)" "Pyruvate carboxyltransferase (21.2%) Carboxylase, conserved domain (21.2%) Pyruvate carboxylase-like (21.2%)" FWDSVSVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella IPR010106 (100%) Recombination-promoting nuclease RpnA (100%) YTGYPGGQR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0006412 (20%) GO:0017148 (20%)" "GO:0022625 (19.9%) GO:0005840 (0.2%) GO:1990904 (0%)" "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" "cytosolic large ribosomal subunit (19.9%) ribosome (0.2%) ribonucleoprotein complex (0%)" "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (25.7%) IPR005823 (25.7%) IPR036899 (25.7%)" "Large ribosomal subunit protein uL13 (25.7%) Large ribosomal subunit protein uL13, bacteria (25.7%) Large ribosomal subunit protein uL13 superfamily (25.7%)" FDSMYGR root "GO:0005891 (33.3%) GO:0016020 (33.3%)" GO:0005245 (33.3%) "voltage-gated calcium channel complex (33.3%) membrane (33.3%)" voltage-gated calcium channel activity (33.3%) "IPR024311 (86.1%) IPR036465 (5.6%) IPR051173 (5.6%)" "Lipocalin-like domain (86.1%) von Willebrand factor A-like domain superfamily (5.6%) Voltage-dependent calcium channel subunit alpha-2/delta (5.6%)" NADVTVDYPGVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR015171 (15.4%) IPR006047 (14.7%) IPR019492 (14.7%)" "Cyclomaltodextrinase, N-terminal (15.4%) Glycosyl hydrolase family 13, catalytic domain (14.7%) Cyclo-malto-dextrinase, C-terminal (14.7%)" AADKVLADDLADLLLLGNPANLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (57.1%) GO:0008959 (42.9%)" "acetyltransferase activity (57.1%) phosphate acetyltransferase activity (42.9%)" "IPR002505 (17%) IPR004614 (17%) IPR050500 (17%)" "Phosphate acetyl/butaryl transferase (17%) Phosphate acetyltransferase (17%) Phosphate Acetyltransferase/Butyryltransferase (17%)" LNDLVFASDLFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.6.3.- (60%) 3.6.3.28 (40%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (60%) Transferred entry: 7.3.2.2 (40%)" "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR003439 (25.3%) IPR017871 (25.3%) IPR003593 (24.7%)" "ABC transporter-like, ATP-binding domain (25.3%) ABC transporter-like, conserved site (25.3%) AAA+ ATPase domain (24.7%)" LVNKDELTQLLLEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.4.2.14 (100%) amidophosphoribosyltransferase (100%) "GO:0009113 (19.8%) GO:0006164 (12.9%) GO:0006189 (6.9%)" "GO:0004044 (19.8%) GO:0046872 (19.8%) GO:0051536 (19.8%)" "purine nucleobase biosynthetic process (19.8%) purine nucleotide biosynthetic process (12.9%) 'de novo' IMP biosynthetic process (6.9%)" "amidophosphoribosyltransferase activity (19.8%) metal ion binding (19.8%) iron-sulfur cluster binding (19.8%)" "IPR000836 (20.8%) IPR017932 (20.8%) IPR029055 (19.8%)" "Phosphoribosyltransferase domain (20.8%) Glutamine amidotransferase type 2 domain (20.8%) Nucleophile aminohydrolases, N-terminal (19.8%)" NVMLNAASANGPR Bacteria Bacteria 3.2.1.65 (100%) levanase (100%) GO:0005987 (0.6%) "GO:0009279 (75.3%) GO:0005737 (0.6%)" "GO:0015344 (22.1%) GO:0004575 (0.6%) GO:0031219 (0.6%)" sucrose catabolic process (0.6%) "cell outer membrane (75.3%) cytoplasm (0.6%)" "siderophore uptake transmembrane transporter activity (22.1%) sucrose alpha-glucosidase activity (0.6%) levanase activity (0.6%)" "IPR036942 (76%) IPR039426 (22.7%) IPR013189 (0.6%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (76%) TonB-dependent receptor-like (22.7%) Glycosyl hydrolase family 32, C-terminal (0.6%)" GLNLNDWLDRK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.3.1.179 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase II (100%) GO:0006633 (33.3%) GO:0005829 (33.3%) GO:0004315 (33.3%) fatty acid biosynthetic process (33.3%) cytosol (33.3%) 3-oxoacyl-[acyl-carrier-protein] synthase activity (33.3%) "IPR000794 (14.3%) IPR014030 (14.3%) IPR014031 (14.3%)" "Beta-ketoacyl synthase (14.3%) Beta-ketoacyl synthase-like, N-terminal (14.3%) Beta-ketoacyl synthase, C-terminal (14.3%)" VLLGDYVTTDDGTGLVHLAPTFGADDAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.4%) "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.4%) "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR002300 (12.7%) IPR002301 (12.7%) IPR013155 (12.7%)" "Aminoacyl-tRNA synthetase, class Ia (12.7%) Isoleucine-tRNA ligase (12.7%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.7%)" FQNALAEGTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0015031 (50%) GO:0005886 (50%) protein transport (50%) plasma membrane (50%) IPR003849 (100%) Preprotein translocase YajC (100%) LLPGGGEANVAVSLANYGHDAYFVSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016301 (100%) kinase activity (100%) "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" SQSAFSEGGLVLGAGLEDLGK Bacteria Bacteria TELRDPQANYNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.24.- (90.9%) 3.4.24.71 (9.1%)" "Metalloendopeptidases (90.9%) endothelin-converting enzyme 1 (9.1%)" GO:0016485 (25.1%) GO:0005886 (25.1%) "GO:0004222 (25.1%) GO:0046872 (24.7%)" protein processing (25.1%) plasma membrane (25.1%) "metalloendopeptidase activity (25.1%) metal ion binding (24.7%)" "IPR000718 (20.4%) IPR008753 (20.4%) IPR018497 (20.2%)" "Peptidase M13 (20.4%) Peptidase M13, N-terminal domain (20.4%) Peptidase M13, C-terminal domain (20.2%)" ELGAQGLLVTPLEK Pseudomonadati Bacteria Pseudomonadati 2.4.2.17 (100%) ATP phosphoribosyltransferase (100%) GO:0000105 (20%) GO:0005737 (20%) "GO:0000287 (20%) GO:0003879 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "magnesium ion binding (20%) ATP phosphoribosyltransferase activity (20%) ATP binding (20%)" "IPR001348 (14.3%) IPR011322 (14.3%) IPR013115 (14.3%)" "ATP phosphoribosyltransferase HisG (14.3%) Nitrogen regulatory PII-like, alpha/beta (14.3%) Histidine biosynthesis HisG, C-terminal (14.3%)" LLATSNDPAEAYEAAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005737 (20%) GO:0015935 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "cytoplasm (20%) small ribosomal subunit (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR001209 (33.3%) IPR018271 (33.3%) IPR023036 (33.3%)" "Small ribosomal subunit protein uS14 (33.3%) Small ribosomal subunit protein uS14, conserved site (33.3%) Small ribosomal subunit protein uS14, bacteria/plastid (33.3%)" GLQEAVSLPVMAK root "4.3.3.6 (99.7%) 4.-.-.- (0.3%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (99.7%) Lyases (0.3%)" "GO:0006520 (24.9%) GO:0008615 (24.9%) GO:0042823 (24.9%)" "GO:0036381 (24.6%) GO:0016843 (0.4%) GO:0016757 (0.1%)" "amino acid metabolic process (24.9%) pyridoxine biosynthetic process (24.9%) pyridoxal phosphate biosynthetic process (24.9%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (24.6%) amine-lyase activity (0.4%) glycosyltransferase activity (0.1%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" LPFLEVAR root "3.5.3.6 (66.7%) 6.3.4.2 (33.3%)" "arginine deiminase (66.7%) CTP synthase (glutamine hydrolyzing) (33.3%)" "GO:0043200 (22%) GO:0006355 (3%) GO:0055085 (0.4%)" "GO:0005829 (22.2%) GO:0005737 (0.5%) GO:0005886 (0.4%)" "GO:0043565 (47.3%) GO:0046872 (0.4%) GO:0003677 (0.2%)" "response to amino acid (22%) regulation of DNA-templated transcription (3%) transmembrane transport (0.4%)" "cytosol (22.2%) cytoplasm (0.5%) plasma membrane (0.4%)" "sequence-specific DNA binding (47.3%) metal ion binding (0.4%) DNA binding (0.2%)" "IPR000485 (15.1%) IPR036388 (15%) IPR036390 (15%)" "AsnC-type HTH domain (15.1%) Winged helix-like DNA-binding domain superfamily (15%) Winged helix DNA-binding domain superfamily (15%)" TGQAQDANALLLPK Bacteria Bacteria 1.3.99.1 (100%) Deleted entry (100%) "GO:0009060 (24.2%) GO:0022904 (24.2%)" "GO:0009055 (24.2%) GO:0051537 (24.2%) GO:0016491 (2.6%)" "aerobic respiration (24.2%) respiratory electron transport chain (24.2%)" "electron transfer activity (24.2%) 2 iron, 2 sulfur cluster binding (24.2%) oxidoreductase activity (2.6%)" "IPR012675 (13.8%) IPR036010 (13.8%) IPR006058 (13.5%)" "Beta-grasp domain superfamily (13.8%) 2Fe-2S ferredoxin-like superfamily (13.8%) 2Fe-2S ferredoxin, iron-sulphur binding site (13.5%)" LPVLTYLNPLDR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0051301 (10.1%) GO:0051603 (10.1%) GO:0006508 (0%)" GO:0009376 (10%) "GO:0005524 (10.1%) GO:0016887 (10.1%) GO:0051082 (10%)" "cell division (10.1%) proteolysis involved in protein catabolic process (10.1%) proteolysis (0%)" HslUV protease complex (10%) "ATP binding (10.1%) ATP hydrolysis activity (10.1%) unfolded protein binding (10%)" "IPR019489 (11%) IPR050052 (11%) IPR003593 (11%)" "Clp ATPase, C-terminal (11%) ATP-dependent Clp protease ATP-binding subunit ClpX (11%) AAA+ ATPase domain (11%)" WVEDATYTLHYGDLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0045493 (50%) GO:0016798 (50%) xylan catabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR025112 (51.9%) IPR038653 (48.1%)" "Putative carbohydrate metabolism domain (51.9%) Putative carbohydrate metabolism domain superfamily (48.1%)" GEVSVYNENFFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.4%) GO:0009341 (25.4%) "GO:0004565 (25.4%) GO:0030246 (23.9%)" lactose catabolic process (25.4%) beta-galactosidase complex (25.4%) "beta-galactosidase activity (25.4%) carbohydrate binding (23.9%)" "IPR004199 (7.4%) IPR006102 (7.4%) IPR006103 (7.4%)" "Beta galactosidase small chain/ domain 5 (7.4%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.4%) Glycoside hydrolase family 2, catalytic domain (7.4%)" WGNPEDYLQLNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (34%) "GO:0004553 (34%) GO:0030246 (32%)" carbohydrate metabolic process (34%) "hydrolase activity, hydrolyzing O-glycosyl compounds (34%) carbohydrate binding (32%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" YDLTGTELDAEADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.9 (100%) dihydroxy-acid dehydratase (100%) "GO:0009097 (16.3%) GO:0009099 (16.3%)" GO:0005829 (17.4%) "GO:0000287 (16.3%) GO:0004160 (16.3%) GO:0051537 (16.3%)" "isoleucine biosynthetic process (16.3%) L-valine biosynthetic process (16.3%)" cytosol (17.4%) "magnesium ion binding (16.3%) dihydroxy-acid dehydratase activity (16.3%) 2 iron, 2 sulfur cluster binding (16.3%)" "IPR000581 (17.6%) IPR056740 (17.6%) IPR004404 (16.5%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, N-terminal (17.6%) Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (17.6%) Dihydroxy-acid dehydratase (16.5%)" NKDLLPNTNMSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006826 (11.1%) GO:0044718 (4.4%)" GO:0009279 (80%) GO:0015344 (4.4%) "iron ion transport (11.1%) siderophore transmembrane transport (4.4%)" cell outer membrane (80%) siderophore uptake transmembrane transporter activity (4.4%) "IPR012910 (13.9%) IPR023996 (13.9%) IPR023997 (13.9%)" "TonB-dependent receptor, plug domain (13.9%) TonB-dependent outer membrane protein, SusC/RagA (13.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.9%)" ANFTVNVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005976 (48.5%) GO:0006508 (1.5%)" "GO:0052689 (48.5%) GO:0008234 (1.5%)" "polysaccharide metabolic process (48.5%) proteolysis (1.5%)" "carboxylic ester hydrolase activity (48.5%) cysteine-type peptidase activity (1.5%)" "IPR008391 (32%) IPR039069 (32%) IPR029058 (30.1%)" "Acetyl xylan esterase domain (32%) Carbohydrate esterase 7 family (32%) Alpha/Beta hydrolase fold (30.1%)" SGFDPATTTYEQGSVAYLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.8%) IPR033985 (33.8%) IPR012944 (32.4%)" "Tetratricopeptide-like helical domain superfamily (33.8%) SusD-like, N-terminal (33.8%) RagB/SusD domain (32.4%)" SREEVSLPWGGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.9%) IPR000795 (7.9%) IPR005225 (7.9%)" "Elongation factor EFG, domain V-like (7.9%) Translational (tr)-type GTP-binding domain (7.9%) Small GTP-binding domain (7.9%)" LLQDADDLYLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.5.2 (100%) GMP synthase (glutamine-hydrolyzing) (100%) GO:0005829 (33%) "GO:0003921 (33%) GO:0005524 (33%) GO:0016740 (1.1%)" cytosol (33%) "GMP synthase activity (33%) ATP binding (33%) transferase activity (1.1%)" "IPR001674 (12.9%) IPR025777 (12.9%) IPR004739 (12.4%)" "GMP synthase, C-terminal (12.9%) GMP synthetase ATP pyrophosphatase domain (12.9%) GMP synthase, glutamine amidotransferase (12.4%)" HVDALLVLNNER Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "GO:0000917 (14.5%) GO:0043093 (13.4%) GO:0051258 (13.4%)" "GO:0005737 (14.6%) GO:0032153 (14.6%)" "GO:0003924 (14.6%) GO:0005525 (14.6%)" "division septum assembly (14.5%) FtsZ-dependent cytokinesis (13.4%) protein polymerization (13.4%)" "cytoplasm (14.6%) cell division site (14.6%)" "GTPase activity (14.6%) GTP binding (14.6%)" "IPR000158 (11.4%) IPR003008 (11.4%) IPR045061 (11.4%)" "Cell division protein FtsZ (11.4%) Tubulin/FtsZ, GTPase domain (11.4%) Tubulin-like protein FtsZ/CetZ (11.4%)" SSDYNYLSSPDDVYVASSFVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.4%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.4%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.8%) IPR003593 (10.8%) IPR004665 (10.8%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.8%) AAA+ ATPase domain (10.8%) Transcription termination factor Rho (10.8%)" QFFLGEQMFER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0004130 (36.6%) GO:0009055 (31.7%) GO:0020037 (31.7%)" "cytochrome-c peroxidase activity (36.6%) electron transfer activity (31.7%) heme binding (31.7%)" "IPR010538 (34.9%) IPR051395 (34.9%) IPR036909 (30.2%)" "Di-haem oxidoreductase, putative peroxidase (34.9%) Cytochrome c-dependent Peroxidase and MauG (34.9%) Cytochrome c-like domain superfamily (30.2%)" ELGVVLTEHYYGNEPQKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR033985 (34.1%) IPR011990 (32.9%) IPR012944 (32.9%)" "SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (32.9%) RagB/SusD domain (32.9%)" TAGDDLTADLQEYMSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000902 (24.8%) GO:0008360 (24.8%)" GO:0005737 (24.8%) "GO:0005524 (24.8%) GO:0016787 (0.8%)" "cell morphogenesis (24.8%) regulation of cell shape (24.8%)" cytoplasm (24.8%) "ATP binding (24.8%) hydrolase activity (0.8%)" "IPR004753 (33%) IPR043129 (33%) IPR056546 (33%)" "Cell shape determining protein MreB (33%) ATPase, nucleotide binding domain (33%) MreB/MamK-like (33%)" GTPFGTFVPTMK Bacteria Bacteria "4.2.1.7 (77.5%) 4.2.1.42 (22.5%)" "altronate dehydratase (77.5%) galactarate dehydratase (22.5%)" GO:0019698 (42.2%) "GO:0016829 (35.6%) GO:0016787 (15.8%) GO:0008789 (4.5%)" D-galacturonate catabolic process (42.2%) "lyase activity (35.6%) hydrolase activity (15.8%) altronate dehydratase activity (4.5%)" "IPR048332 (20.4%) IPR052172 (20.4%) IPR007392 (19.9%)" "D-galactarate/Altronate dehydratase, C-terminal domain (20.4%) UxaA family altronate/galactarate dehydratases (20.4%) D-galactarate/Altronate dehydratase, second domain (19.9%)" LLVQQEPDASSFPSGGLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (50%) GO:0004356 (50%) glutamine biosynthetic process (50%) glutamine synthetase activity (50%) "IPR008147 (14.5%) IPR022147 (14.5%) IPR052725 (14.5%)" "Glutamine synthetase, N-terminal domain (14.5%) Glutamine synthetase type III N-terminal (14.5%) Glutamine Synthetase Type-3 (14.5%)" FNYTADYNGNNDGNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" EYYGVEVGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) CFDDDNLVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005737 (19.9%) GO:0016020 (0.7%)" "GO:0005524 (19.9%) GO:0005525 (19.9%) GO:0016887 (19.9%)" "cytoplasm (19.9%) membrane (0.7%)" "ATP binding (19.9%) GTP binding (19.9%) ATP hydrolysis activity (19.9%)" "IPR004095 (10.3%) IPR004396 (10.3%) IPR006073 (10.3%)" "TGS (10.3%) Ribosome-binding ATPase YchF/Obg-like ATPase 1 (10.3%) GTP binding domain (10.3%)" TWSYTNDLPSVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" FVATLDGGK root "1.1.1.3 (50.8%) 2.7.2.4 (49.2%)" "homoserine dehydrogenase (50.8%) aspartate kinase (49.2%)" "GO:0009086 (11.1%) GO:0009088 (11.1%) GO:0009089 (11.1%)" GO:0005762 (0.3%) "GO:0004072 (11.1%) GO:0004412 (11.1%) GO:0005524 (11.1%)" "methionine biosynthetic process (11.1%) threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%)" mitochondrial large ribosomal subunit (0.3%) "aspartate kinase activity (11.1%) homoserine dehydrogenase activity (11.1%) ATP binding (11.1%)" "IPR001048 (7.2%) IPR001341 (7.2%) IPR001342 (7.2%)" "Aspartate/glutamate/uridylate kinase (7.2%) Aspartate kinase (7.2%) Homoserine dehydrogenase, catalytic (7.2%)" KVAELDAELK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006364 (16.7%) GO:0005737 (16.7%) "GO:0003723 (16.7%) GO:0004540 (16.7%) GO:0016787 (16.7%)" rRNA processing (16.7%) cytoplasm (16.7%) "RNA binding (16.7%) RNA nuclease activity (16.7%) hydrolase activity (16.7%)" "IPR003029 (25.8%) IPR004659 (25.8%) IPR019307 (25.8%)" "S1 domain (25.8%) Ribonuclease E/G (25.8%) RNA-binding protein AU-1/Ribonuclease E/G (25.8%)" CWPAFPSQFGFEPCYVNSR Bacteria Bacteria "GO:0006004 (31.9%) GO:0005996 (1.4%)" GO:0005737 (33.3%) "GO:0008736 (31.9%) GO:0016861 (1.4%)" "fucose metabolic process (31.9%) monosaccharide metabolic process (1.4%)" cytoplasm (33.3%) "L-fucose isomerase activity (31.9%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (1.4%)" "IPR009015 (50.4%) IPR015888 (49.6%)" "L-fucose isomerase, N-terminal/central domain superfamily (50.4%) L-fucose isomerase, C-terminal (49.6%)" MAEQACTTYGYQPSEK Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (33%) GO:0005829 (33.3%) "GO:0008861 (33.3%) GO:0016829 (0.4%)" glucose metabolic process (33%) cytosol (33.3%) "formate C-acetyltransferase activity (33.3%) lyase activity (0.4%)" "IPR004184 (20.1%) IPR050244 (20.1%) IPR001150 (19.9%)" "Pyruvate formate lyase domain (20.1%) Autonomous Glycyl Radical Cofactor (20.1%) Glycine radical domain (19.9%)" LDMFFAK root "1.17.4.2 (53.5%) 2.7.7.7 (46.5%)" "ribonucleoside-triphosphate reductase (thioredoxin) (53.5%) DNA-directed DNA polymerase (46.5%)" "GO:0006260 (14.9%) GO:0009265 (8.5%) GO:0042276 (6%)" "GO:0031250 (8.5%) GO:0005634 (6.7%) GO:0005737 (0.6%)" "GO:0004748 (8.5%) GO:0005524 (8.5%) GO:0008998 (8.5%)" "DNA replication (14.9%) 2'-deoxyribonucleotide biosynthetic process (8.5%) error-prone translesion synthesis (6%)" "anaerobic ribonucleoside-triphosphate reductase complex (8.5%) nucleus (6.7%) cytoplasm (0.6%)" "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (8.5%) ATP binding (8.5%) ribonucleoside-triphosphate reductase (thioredoxin) activity (8.5%)" "IPR005144 (11.5%) IPR012833 (11.5%) IPR041298 (9.3%)" "ATP-cone domain (11.5%) Ribonucleoside-triphosphate reductase, anaerobic (11.5%) DNA polymerase eta, ubiquitin-binding zinc finger (9.3%)" NQAFDELFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009247 (33.3%) GO:0005886 (33.3%) GO:0016746 (33.3%) glycolipid biosynthetic process (33.3%) plasma membrane (33.3%) acyltransferase activity (33.3%) IPR004960 (100%) Bacterial lipid A biosynthesis acyltransferase (100%) FAVEVQDNWR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006508 (20.9%) GO:0009636 (19.4%) GO:0043418 (19.4%)" GO:0005737 (19.4%) GO:0070005 (20.9%) "proteolysis (20.9%) response to toxic substance (19.4%) homocysteine catabolic process (19.4%)" cytoplasm (19.4%) cysteine-type aminopeptidase activity (20.9%) "IPR004134 (40.1%) IPR038765 (39.3%) IPR000169 (11.9%)" "Peptidase C1B, bleomycin hydrolase (40.1%) Papain-like cysteine peptidase superfamily (39.3%) Cysteine peptidase, cysteine active site (11.9%)" EFLPSVQK root "2.1.3.2 (25%) 3.5.1.2 (25%) 6.3.4.16 (25%)" "aspartate carbamoyltransferase (25%) glutaminase (25%) carbamoyl-phosphate synthase (ammonia) (25%)" "GO:0032790 (19.1%) GO:0032259 (0.7%) GO:0044550 (0.7%)" "GO:0005737 (17.9%) GO:0005951 (0.2%) GO:0000139 (0.1%)" "GO:0003746 (19.1%) GO:0005525 (19.1%) GO:0003924 (18.3%)" "ribosome disassembly (19.1%) methylation (0.7%) secondary metabolite biosynthetic process (0.7%)" "cytoplasm (17.9%) carbamoyl-phosphate synthase complex (0.2%) Golgi membrane (0.1%)" "translation elongation factor activity (19.1%) GTP binding (19.1%) GTPase activity (18.3%)" "IPR005517 (6.1%) IPR009022 (6.1%) IPR041095 (6.1%)" "Translation elongation factor EFG/EF2, domain IV (6.1%) Elongation factor G, domain III (6.1%) Elongation Factor G, domain II (6.1%)" TATSDQAEEMLAYLR Pseudomonadati Bacteria Pseudomonadati 5.3.1.1 (100%) triose-phosphate isomerase (100%) "GO:0006094 (12.9%) GO:0006096 (12.9%) GO:0019563 (12.9%)" "GO:0005829 (12.9%) GO:0016020 (11.3%)" GO:0004807 (12.9%) "gluconeogenesis (12.9%) glycolytic process (12.9%) glycerol catabolic process (12.9%)" "cytosol (12.9%) membrane (11.3%)" triose-phosphate isomerase activity (12.9%) "IPR000652 (17.2%) IPR020861 (17.2%) IPR022896 (17%)" "Triosephosphate isomerase (17.2%) Triosephosphate isomerase, active site (17.2%) Triosephosphate isomerase, bacterial/eukaryotic (17%)" EANDQAVHDFLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016627 (50.6%) GO:0050660 (49.4%)" "oxidoreductase activity, acting on the CH-CH group of donors (50.6%) flavin adenine dinucleotide binding (49.4%)" "IPR009075 (10.3%) IPR020964 (10.3%) IPR052166 (10.3%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10.3%) Acyl-CoA dehydrogenase, C-terminal (10.3%) Diverse substrate specificity acyl-CoA dehydrogenase (10.3%)" TFHAGGLASNAAANAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.7%) GO:0000428 (16.7%) "GO:0000287 (16.7%) GO:0003677 (16.7%) GO:0003899 (16.7%)" DNA-templated transcription (16.7%) DNA-directed RNA polymerase complex (16.7%) "magnesium ion binding (16.7%) DNA binding (16.7%) DNA-directed RNA polymerase activity (16.7%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" TEDDEFVSFEPALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR015712 (8.5%) IPR007120 (8.1%) IPR007645 (8.1%)" "DNA-directed RNA polymerase, subunit 2 (8.5%) DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (8.1%) RNA polymerase Rpb2, domain 3 (8.1%)" AGNTSLEELAMLLK Bacteria Bacteria 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.8%) GO:0005737 (19.4%) "GO:0003852 (20.8%) GO:0003985 (19.4%) GO:0030145 (19.4%)" L-leucine biosynthetic process (20.8%) cytoplasm (19.4%) "2-isopropylmalate synthase activity (20.8%) acetyl-CoA C-acetyltransferase activity (19.4%) manganese ion binding (19.4%)" "IPR000891 (12.8%) IPR002034 (12.8%) IPR013785 (12.8%)" "Pyruvate carboxyltransferase (12.8%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.8%) Aldolase-type TIM barrel (12.8%)" ECALLTDGR root "4.2.1.9 (99.9%) 4.-.-.- (0.1%)" "dihydroxy-acid dehydratase (99.9%) Lyases (0.1%)" "GO:0009097 (15.1%) GO:0009099 (15.1%) GO:0009082 (1.8%)" "GO:0005829 (13.8%) GO:0009570 (2.4%) GO:0005874 (0%)" "GO:0004160 (16.7%) GO:0051537 (16.2%) GO:0000287 (13.1%)" "isoleucine biosynthetic process (15.1%) L-valine biosynthetic process (15.1%) branched-chain amino acid biosynthetic process (1.8%)" "cytosol (13.8%) chloroplast stroma (2.4%) microtubule (0%)" "dihydroxy-acid dehydratase activity (16.7%) 2 iron, 2 sulfur cluster binding (16.2%) magnesium ion binding (13.1%)" "IPR056740 (16.3%) IPR020558 (16.3%) IPR042096 (16.2%)" "Dihydroxy-acid/6-phosphogluconate dehydratase, C-terminal (16.3%) Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site (16.3%) Dihydroxy-acid dehydratase, C-terminal (16.2%)" LEEGKEGALSFLSNPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.3.1.191 (96.6%) 2.3.1.- (3.4%)" "UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase (96.6%) Transferring groups other than amino-acyl groups (3.4%)" GO:0009245 (33.3%) GO:0016020 (33.3%) GO:0016410 (33.3%) lipid A biosynthetic process (33.3%) membrane (33.3%) N-acyltransferase activity (33.3%) "IPR001451 (20.1%) IPR007691 (20.1%) IPR011004 (20.1%)" "Hexapeptide repeat (20.1%) UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD (20.1%) Trimeric LpxA-like superfamily (20.1%)" VGLNVSTLGDNDWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR027385 (100%) Outer membrane protein, beta-barrel domain (100%) WRVPGQLTDVPK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" FLENASFLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (6.6%) GO:0006826 (1.3%)" GO:0009279 (84.2%) "GO:0015344 (6.6%) GO:0030246 (1.3%)" "siderophore transmembrane transport (6.6%) iron ion transport (1.3%)" cell outer membrane (84.2%) "siderophore uptake transmembrane transporter activity (6.6%) carbohydrate binding (1.3%)" "IPR012910 (12.8%) IPR023996 (12.8%) IPR039426 (12.8%)" "TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%) TonB-dependent receptor-like (12.8%)" WNPAMAPYLFMER Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (33.3%) "GO:0022627 (33.3%) GO:0005840 (0.2%)" GO:0003735 (33.3%) translation (33.3%) "cytosolic small ribosomal subunit (33.3%) ribosome (0.2%)" structural constituent of ribosome (33.3%) "IPR001865 (25.2%) IPR005706 (25.2%) IPR023591 (25.2%)" "Small ribosomal subunit protein uS2 (25.2%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25.2%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (25.2%)" LAGETMDNVDYSR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" LDYSALKDAEFVQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) VVYGALGK root 4.2.1.49 (100%) urocanate hydratase (100%) "GO:0019556 (3.1%) GO:0019557 (3.1%) GO:0045892 (3.1%)" "GO:0005737 (1%) GO:0005829 (1%) GO:0016020 (1%)" "GO:0003677 (77.1%) GO:0003700 (3.1%) GO:0016153 (3.1%)" "L-histidine catabolic process to glutamate and formamide (3.1%) L-histidine catabolic process to glutamate and formate (3.1%) negative regulation of DNA-templated transcription (3.1%)" "cytoplasm (1%) cytosol (1%) membrane (1%)" "DNA binding (77.1%) DNA-binding transcription factor activity (3.1%) urocanate hydratase activity (3.1%)" "IPR001647 (29.6%) IPR009057 (29.6%) IPR050624 (28%)" "DNA-binding HTH domain, TetR-type (29.6%) Homedomain-like superfamily (29.6%) HTH-type Transcriptional Regulator (28%)" SAGYDAQLALNTER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0051301 (11.1%) GO:0042834 (88.9%) cell division (11.1%) peptidoglycan binding (88.9%) "IPR007730 (50%) IPR036680 (50%)" "Sporulation-like domain (50%) Sporulation-like domain superfamily (50%)" REENSLSLAATADK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.10.2 (100%) non-specific protein-tyrosine kinase (100%) GO:0005886 (25.1%) "GO:0005524 (25.1%) GO:0042802 (24.8%) GO:0004713 (20.6%)" plasma membrane (25.1%) "ATP binding (25.1%) identical protein binding (24.8%) protein tyrosine kinase activity (20.6%)" "IPR005702 (17.9%) IPR025669 (17.9%) IPR050445 (17.9%)" "Tyrosine-protein kinase Wzc-like, C-terminal domain (17.9%) AAA domain (17.9%) Bacterial polysaccharide biosynthesis and export (17.9%)" GGVREDGAPLQPNDDQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.58 (100%) tagaturonate reductase (100%) GO:0019592 (32.7%) GO:0005829 (32.7%) "GO:0008926 (32.7%) GO:0009026 (1.9%)" mannitol catabolic process (32.7%) cytosol (32.7%) "mannitol-1-phosphate 5-dehydrogenase activity (32.7%) tagaturonate reductase activity (1.9%)" "IPR013118 (21.5%) IPR013131 (21.5%) IPR008927 (19%)" "Mannitol dehydrogenase, C-terminal (21.5%) Mannitol dehydrogenase, N-terminal (21.5%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (19%)" TDGSAVAELVFSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0017004 (25%) GO:0045454 (25%)" "GO:0005886 (23.1%) GO:0016020 (1.9%)" GO:0015035 (25%) "cytochrome complex assembly (25%) cell redox homeostasis (25%)" "plasma membrane (23.1%) membrane (1.9%)" protein-disulfide reductase activity (25%) "IPR003834 (25.5%) IPR013766 (25.5%) IPR028250 (25.5%)" "Cytochrome C biogenesis protein, transmembrane domain (25.5%) Thioredoxin domain (25.5%) Thiol:disulfide interchange protein DsbD, N-terminal domain (25.5%)" ETLPEGYGYEYSGLTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009636 (24.6%) GO:0005886 (25.4%) "GO:0042910 (25.4%) GO:0015562 (24.6%)" response to toxic substance (24.6%) plasma membrane (25.4%) "xenobiotic transmembrane transporter activity (25.4%) efflux transmembrane transporter activity (24.6%)" "IPR001036 (33.7%) IPR027463 (33.7%) IPR004764 (32.7%)" "Acriflavin resistance protein (33.7%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.7%) Multidrug resistance protein MdtF-like (32.7%)" VDNYSLPGLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR023614 (100%) Porin domain superfamily (100%) LFGFENYEAQLSLRDPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.7%) GO:0005737 (16.7%) "GO:0000049 (16.7%) GO:0004829 (16.7%) GO:0005524 (16.7%)" threonyl-tRNA aminoacylation (16.7%) cytoplasm (16.7%) "tRNA binding (16.7%) threonine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002314 (7.7%) IPR002320 (7.7%) IPR004095 (7.7%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (7.7%) Threonine-tRNA ligase, class IIa (7.7%) TGS (7.7%)" KWLYQTPEQLLLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) "GO:0006189 (19.1%) GO:0006164 (1.1%)" GO:0005737 (20.1%) "GO:0004642 (20.1%) GO:0005524 (19.6%) GO:0046872 (19.6%)" "'de novo' IMP biosynthetic process (19.1%) purine nucleotide biosynthetic process (1.1%)" cytoplasm (20.1%) "phosphoribosylformylglycinamidine synthase activity (20.1%) ATP binding (19.6%) metal ion binding (19.6%)" "IPR010918 (11.3%) IPR036921 (11.3%) IPR036676 (11.2%)" "PurM-like, C-terminal domain (11.3%) PurM-like, N-terminal domain superfamily (11.3%) PurM-like, C-terminal domain superfamily (11.2%)" LPSPALLAEAFGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (26.2%) IPR020845 (25.4%) IPR042099 (24.6%)" "AMP-dependent synthetase/ligase domain (26.2%) AMP-binding, conserved site (25.4%) ANL, N-terminal domain (24.6%)" YEGNPVLTPFDGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.65 (100%) levanase (100%) GO:0005987 (33.1%) GO:0005737 (33.1%) "GO:0004575 (33.1%) GO:0031219 (0.8%)" sucrose catabolic process (33.1%) cytoplasm (33.1%) "sucrose alpha-glucosidase activity (33.1%) levanase activity (0.8%)" "IPR001362 (14.7%) IPR013148 (14.7%) IPR018053 (14.7%)" "Glycoside hydrolase, family 32 (14.7%) Glycosyl hydrolase family 32, N-terminal (14.7%) Glycoside hydrolase, family 32, active site (14.7%)" MLLVPVKDGENLER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001911 (48.7%) IPR038380 (48.7%) IPR018278 (2.5%)" "Small ribosomal subunit protein bS21 (48.7%) Small ribosomal subunit protein bS21 superfamily (48.7%) Small ribosomal subunit protein bS21, conserved site (2.5%)" EVEVLDADGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0000028 (33.3%) GO:0006412 (33.3%)" GO:0005829 (33.3%) "ribosomal small subunit assembly (33.3%) translation (33.3%)" cytosol (33.3%) "IPR003728 (29.5%) IPR028989 (29.5%) IPR035956 (27.3%)" "Ribosome maturation factor RimP (29.5%) Ribosome maturation factor RimP, N-terminal (29.5%) RimP, N-terminal domain superfamily (27.3%)" LLAHNGELNTLR root "1.4.1.13 (80.1%) 1.4.1.14 (15.9%) 1.4.7.1 (4%)" "glutamate synthase (NADPH) (80.1%) glutamate synthase (NADH) (15.9%) glutamate synthase (ferredoxin) (4%)" "GO:0019676 (18.1%) GO:0006537 (16.7%) GO:0097054 (1.7%)" "GO:0051538 (18.3%) GO:0046872 (15.1%) GO:0015930 (8.3%)" "ammonia assimilation cycle (18.1%) glutamate biosynthetic process (16.7%) L-glutamate biosynthetic process (1.7%)" "3 iron, 4 sulfur cluster binding (18.3%) metal ion binding (15.1%) glutamate synthase activity (8.3%)" "IPR017932 (11.6%) IPR029055 (11.5%) IPR006982 (11.2%)" "Glutamine amidotransferase type 2 domain (11.6%) Nucleophile aminohydrolases, N-terminal (11.5%) Glutamate synthase, central-N (11.2%)" VNPGGYHTYPQALEQFTVSDER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009228 (24.7%) "GO:0051539 (25.9%) GO:0005506 (24.7%) GO:0003824 (22.4%)" thiamine biosynthetic process (24.7%) "4 iron, 4 sulfur cluster binding (25.9%) iron ion binding (24.7%) catalytic activity (22.4%)" "IPR010722 (20.6%) IPR034428 (20.6%) IPR007197 (19.6%)" "Biotin and thiamin synthesis-associated domain (20.6%) ThiH/NocL/HydG-like (20.6%) Radical SAM (19.6%)" ESLLLDLKNEQTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" YPNLDMYSSDYLRK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" LLNSTNDFPEFTGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.4.1.13 (42.9%) 1.4.1.14 (42.9%) 1.4.1.- (14.3%)" "glutamate synthase (NADPH) (42.9%) glutamate synthase (NADH) (42.9%) With NAD(+) or NADP(+) as acceptor (14.3%)" GO:0006537 (31.7%) "GO:0051536 (33.3%) GO:0016639 (31.7%) GO:0004355 (1.6%)" glutamate biosynthetic process (31.7%) "iron-sulfur cluster binding (33.3%) oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor (31.7%) glutamate synthase (NADPH) activity (1.6%)" "IPR009051 (17%) IPR028261 (17%) IPR051394 (17%)" "Alpha-helical ferredoxin (17%) Dihydroprymidine dehydrogenase domain II (17%) Glutamate Synthase (17%)" KLDGFDPGMDSYVQR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.2%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.2%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" DLLNAFDKEGDEVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" RFYFDPDATLAELNAQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" AGDTLTVAYK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (33.3%) GO:0022625 (33.3%) GO:0003735 (33.3%) translation (33.3%) cytosolic large ribosomal subunit (33.3%) structural constituent of ribosome (33.3%) "IPR001857 (25.1%) IPR008991 (25.1%) IPR038657 (25.1%)" "Large ribosomal subunit protein bL19 (25.1%) Translation protein SH3-like domain superfamily (25.1%) Large ribosomal subunit protein bL19 superfamily (25.1%)" EPGGTSQSLWGYVGNYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.99.28 (100%) peptidoglycan glycosyltransferase (100%) "GO:0008360 (11.4%) GO:0009252 (11.4%) GO:0071555 (11.4%)" "GO:0030288 (11.4%) GO:0005886 (10.2%) GO:0016020 (1.2%)" "GO:0008658 (11.4%) GO:0008955 (11.4%) GO:0004180 (10.2%)" "regulation of cell shape (11.4%) peptidoglycan biosynthetic process (11.4%) cell wall organization (11.4%)" "outer membrane-bounded periplasmic space (11.4%) plasma membrane (10.2%) membrane (1.2%)" "penicillin binding (11.4%) peptidoglycan glycosyltransferase activity (11.4%) carboxypeptidase activity (10.2%)" "IPR001460 (17.6%) IPR050396 (17.6%) IPR001264 (16.7%)" "Penicillin-binding protein, transpeptidase (17.6%) Glycosyltransferase 51/Transpeptidase (17.6%) Glycosyl transferase, family 51 (16.7%)" DVSGEGVQQGLLK root "3.4.21.92 (88.9%) 7.1.2.2 (11.1%)" "endopeptidase Clp (88.9%) H(+)-transporting two-sector ATPase (11.1%)" "GO:0051603 (10.6%) GO:0051301 (9.5%) GO:0030150 (0%)" "GO:0009376 (9.5%) GO:0005759 (0.7%) GO:0009536 (0.1%)" "GO:0005524 (10.6%) GO:0016887 (10.6%) GO:0051082 (9.9%)" "proteolysis involved in protein catabolic process (10.6%) cell division (9.5%) protein import into mitochondrial matrix (0%)" "HslUV protease complex (9.5%) mitochondrial matrix (0.7%) plastid (0.1%)" "ATP binding (10.6%) ATP hydrolysis activity (10.6%) unfolded protein binding (9.9%)" "IPR003959 (11.4%) IPR050052 (11.3%) IPR027417 (11.3%)" "ATPase, AAA-type, core (11.4%) ATP-dependent Clp protease ATP-binding subunit ClpX (11.3%) P-loop containing nucleoside triphosphate hydrolase (11.3%)" HPFPGPGLAVR root "6.3.5.2 (99.9%) 3.2.1.39 (0.1%) 6.3.1.5 (0.1%)" "GMP synthase (glutamine-hydrolyzing) (99.9%) glucan endo-1,3-beta-D-glucosidase (0.1%) NAD(+) synthase (0.1%)" "GO:0006177 (1.2%) GO:0006529 (0.7%) GO:0005975 (0%)" "GO:0005829 (31.4%) GO:0016020 (0.2%) GO:0005886 (0%)" "GO:0003921 (32.1%) GO:0005524 (32.1%) GO:0016740 (1%)" "GMP biosynthetic process (1.2%) obsolete asparagine biosynthetic process (0.7%) carbohydrate metabolic process (0%)" "cytosol (31.4%) membrane (0.2%) plasma membrane (0%)" "GMP synthase activity (32.1%) ATP binding (32.1%) transferase activity (1%)" "IPR001674 (13.9%) IPR025777 (13.8%) IPR014729 (13.7%)" "GMP synthase, C-terminal (13.9%) GMP synthetase ATP pyrophosphatase domain (13.8%) Rossmann-like alpha/beta/alpha sandwich fold (13.7%)" TPGNTVSNLSSTR Bacteroidota Bacteria Pseudomonadati Bacteroidota "5.4.2.10 (84.5%) 5.4.2.2 (8.8%) 5.4.2.8 (6.7%)" "phosphoglucosamine mutase (84.5%) phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) (8.8%) phosphomannomutase (6.7%)" "GO:0005975 (14.3%) GO:0006048 (14.1%) GO:0009252 (14.1%)" GO:0005829 (14.1%) "GO:0004615 (14.1%) GO:0008966 (14.1%) GO:0000287 (13.9%)" "carbohydrate metabolic process (14.3%) UDP-N-acetylglucosamine biosynthetic process (14.1%) peptidoglycan biosynthetic process (14.1%)" cytosol (14.1%) "phosphomannomutase activity (14.1%) phosphoglucosamine mutase activity (14.1%) magnesium ion binding (13.9%)" "IPR005845 (10.1%) IPR005846 (10.1%) IPR016055 (10.1%)" "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II (10.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha domain III (10.1%) Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III (10.1%)" YKDVVLQCCASGGGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR031704 (12.9%) IPR031705 (12.9%)" "Glycoside hydrolase family 36 (12.9%) Glycosyl hydrolase family 36, N-terminal (12.9%) Glycosyl hydrolase family 36, C-terminal (12.9%)" TGCLEAYCSATGVAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.1.2 (100%) glucokinase (100%) "GO:0016301 (53.8%) GO:0004340 (38.5%) GO:0016740 (7.7%)" "kinase activity (53.8%) glucokinase activity (38.5%) transferase activity (7.7%)" "IPR000600 (33.8%) IPR049874 (33.8%) IPR043129 (32.4%)" "ROK family (33.8%) ROK, conserved site (33.8%) ATPase, nucleotide binding domain (32.4%)" NVYLSAR root "3.2.1.14 (38.5%) 6.3.2.1 (30.8%) 1.1.1.100 (7.7%)" "chitinase (38.5%) pantoate--beta-alanine ligase (AMP-forming) (30.8%) 3-oxoacyl-[acyl-carrier-protein] reductase (7.7%)" "GO:0006412 (18.8%) GO:0000380 (0.2%) GO:0005975 (0.2%)" "GO:0005840 (18.9%) GO:1990904 (18.8%) GO:0016020 (0.5%)" "GO:0003735 (18.8%) GO:0019843 (17.3%) GO:0003723 (1%)" "translation (18.8%) alternative mRNA splicing, via spliceosome (0.2%) carbohydrate metabolic process (0.2%)" "ribosome (18.9%) ribonucleoprotein complex (18.8%) membrane (0.5%)" "structural constituent of ribosome (18.8%) rRNA binding (17.3%) RNA binding (1%)" "IPR002136 (28%) IPR023574 (28%) IPR013005 (28%)" "Large ribosomal subunit protein uL4 (28%) Large ribosomal subunit protein uL4 domain superfamily (28%) Large ribosomal subunit protein uL4-like (28%)" DGNMLMPDAKPGDVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" YKNEQNLLDGCQSR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032259 (50%) GO:0008168 (50%) methylation (50%) methyltransferase activity (50%) IPR003808 (100%) Fe-S metabolism associated domain, SufE-like (100%) GWTEALTLMPVGSK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0006457 (50%) GO:0003755 (50%) protein folding (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR000774 (28.5%) IPR001179 (28.5%) IPR046357 (28%)" "Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal (28.5%) FKBP-type peptidyl-prolyl cis-trans isomerase domain (28.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (28%)" NSAEVLNAVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016226 (100%) iron-sulfur cluster assembly (100%) "IPR000825 (20.1%) IPR011542 (20.1%) IPR045595 (20.1%)" "SUF system FeS cluster assembly, SufBD core domain (20.1%) SUF system FeS cluster assembly, SufD (20.1%) SUF system FeS cluster assembly, SufBD, N-terminal (20.1%)" MLYSGSLGYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" YLLQLLNSSATVDDLDHLSNR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007642 (8.1%) IPR007644 (8.1%) IPR015712 (8.1%)" "RNA polymerase Rpb2, domain 2 (8.1%) RNA polymerase, beta subunit, protrusion (8.1%) DNA-directed RNA polymerase, subunit 2 (8.1%)" NLEAAANGEHDEWTDMYPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005506 (50%) GO:0016491 (46.4%) GO:0016692 (3.6%)" "iron ion binding (50%) oxidoreductase activity (46.4%) NADH peroxidase activity (3.6%)" "IPR003251 (14.6%) IPR009040 (14.6%) IPR024934 (14.6%)" "Rubrerythrin, diiron-binding domain (14.6%) Ferritin-like diiron domain (14.6%) Rubredoxin-like domain (14.6%)" EYTGYFVK root GO:0006508 (9.1%) "GO:0009279 (50%) GO:0009986 (4.5%) GO:0016020 (4.5%)" "GO:0046872 (22.7%) GO:0004222 (9.1%)" proteolysis (9.1%) "cell outer membrane (50%) cell surface (4.5%) membrane (4.5%)" "metal ion binding (22.7%) metalloendopeptidase activity (9.1%)" "IPR012944 (18.5%) IPR033985 (18.5%) IPR011990 (16.7%)" "RagB/SusD domain (18.5%) SusD-like, N-terminal (18.5%) Tetratricopeptide-like helical domain superfamily (16.7%)" DLTAMPVKDALEGMQGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.3%) IPR023996 (13.3%) IPR023997 (13.3%)" "TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.3%)" FAGLSPELGLSETQQTLVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0006537 (20.2%) GO:0019676 (19.7%)" "GO:0046872 (19.7%) GO:0051538 (19.7%) GO:0015930 (14.6%)" "glutamate biosynthetic process (20.2%) ammonia assimilation cycle (19.7%)" "metal ion binding (19.7%) 3 iron, 4 sulfur cluster binding (19.7%) glutamate synthase activity (14.6%)" "IPR002932 (12.9%) IPR002489 (12.6%) IPR006982 (12.6%)" "Glutamate synthase domain (12.9%) Glutamate synthase, alpha subunit, C-terminal (12.6%) Glutamate synthase, central-N (12.6%)" SLGNTANDGLVYGNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR051200 (36.6%) IPR015943 (31.7%) IPR011044 (19.5%)" "Multi-functional host-pathogen interaction and enzymatic activity protein (36.6%) WD40/YVTN repeat-like-containing domain superfamily (31.7%) Quinoprotein amine dehydrogenase, beta chain-like (19.5%)" FLGSTTYEEYNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0034605 (21.9%) GO:0006508 (5.3%) GO:0043335 (1.8%)" GO:0005737 (21.9%) "GO:0005524 (21.9%) GO:0016887 (21.9%) GO:0008233 (5.3%)" "cellular response to heat (21.9%) proteolysis (5.3%) protein unfolding (1.8%)" cytoplasm (21.9%) "ATP binding (21.9%) ATP hydrolysis activity (21.9%) peptidase activity (5.3%)" "IPR003593 (9.5%) IPR003959 (9.5%) IPR041546 (9.5%)" "AAA+ ATPase domain (9.5%) ATPase, AAA-type, core (9.5%) ClpA/ClpB, AAA lid domain (9.5%)" GLKLEQATLDMLGSADK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.4%) GO:0005737 (15.9%) "GO:0005524 (17.4%) GO:0140662 (17.4%) GO:0016853 (15.9%)" protein refolding (17.4%) cytoplasm (15.9%) "ATP binding (17.4%) ATP-dependent protein folding chaperone (17.4%) isomerase activity (15.9%)" "IPR001844 (17.1%) IPR002423 (17.1%) IPR027409 (17.1%)" "Chaperonin Cpn60/GroEL (17.1%) Chaperonin Cpn60/GroEL/TCP-1 family (17.1%) GroEL-like apical domain superfamily (17.1%)" KPGVWNVEEFDPDPFMEQLNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.5.1.7 (60%) 1.-.-.- (20%) 1.5.1.43 (20%)" "saccharopine dehydrogenase (NAD(+), L-lysine-forming) (60%) Oxidoreductases (20%) carboxynorspermidine synthase (20%)" "GO:0004754 (60%) GO:0016491 (40%)" "saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (60%) oxidoreductase activity (40%)" "IPR032095 (34.3%) IPR005097 (33.3%) IPR036291 (32.4%)" "Saccharopine dehydrogenase-like, C-terminal (34.3%) Saccharopine dehydrogenase, NADP binding domain (33.3%) NAD(P)-binding domain superfamily (32.4%)" GPAASALYGSR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (15.7%) GO:0006826 (3.4%) GO:0015889 (1.1%)" GO:0009279 (62.7%) GO:0015344 (16.4%) "siderophore transmembrane transport (15.7%) iron ion transport (3.4%) cobalamin transport (1.1%)" cell outer membrane (62.7%) siderophore uptake transmembrane transporter activity (16.4%) "IPR012910 (13.4%) IPR039426 (13.4%) IPR023997 (13.4%)" "TonB-dependent receptor, plug domain (13.4%) TonB-dependent receptor-like (13.4%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.4%)" YNVGFSR root "1.14.13.168 (42.1%) 3.5.1.115 (21.1%) 1.-.-.- (15.8%)" "indole-3-pyruvate monooxygenase (42.1%) mycothiol S-conjugate amidase (21.1%) Oxidoreductases (15.8%)" "GO:0009851 (13.1%) GO:0010126 (4.8%) GO:0010127 (4.8%)" "GO:0005886 (6%) GO:0009279 (4.8%)" "GO:0050660 (11.9%) GO:0050661 (10.7%) GO:0004497 (9.5%)" "auxin biosynthetic process (13.1%) mycothiol metabolic process (4.8%) mycothiol-dependent detoxification (4.8%)" "plasma membrane (6%) cell outer membrane (4.8%)" "flavin adenine dinucleotide binding (11.9%) NADP binding (10.7%) monooxygenase activity (9.5%)" "IPR025631 (32%) IPR036188 (8.8%) IPR050982 (8.8%)" "Putative porin-10 (32%) FAD/NAD(P)-binding domain superfamily (8.8%) Auxin biosynthesis and cation transport (8.8%)" LLAEGEAGDNVGLLLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14.3%) GO:0032045 (14.3%)" "GO:0000287 (14.3%) GO:0003746 (14.3%) GO:0003924 (14.3%)" "cytosol (14.3%) guanyl-nucleotide exchange factor complex (14.3%)" "magnesium ion binding (14.3%) translation elongation factor activity (14.3%) GTPase activity (14.3%)" "IPR000795 (8.3%) IPR004160 (8.3%) IPR004161 (8.3%)" "Translational (tr)-type GTP-binding domain (8.3%) Translation elongation factor EFTu/EF1A, C-terminal (8.3%) Translation elongation factor EFTu-like, domain 2 (8.3%)" SVGEVMALGR root "6.3.4.16 (48.3%) 6.3.5.5 (42.5%) 2.1.3.2 (3.3%)" "carbamoyl-phosphate synthase (ammonia) (48.3%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (42.5%) aspartate carbamoyltransferase (3.3%)" "GO:0006541 (10.7%) GO:0006207 (6.9%) GO:0006526 (6.1%)" "GO:0005829 (5.5%) GO:0005737 (4%) GO:0005951 (1.2%)" "GO:0005524 (11.5%) GO:0004088 (11.5%) GO:0046872 (9.1%)" "glutamine metabolic process (10.7%) 'de novo' pyrimidine nucleobase biosynthetic process (6.9%) L-arginine biosynthetic process (6.1%)" "cytosol (5.5%) cytoplasm (4%) carbamoyl-phosphate synthase complex (1.2%)" "ATP binding (11.5%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (11.5%) metal ion binding (9.1%)" "IPR005480 (11.3%) IPR036897 (11.2%) IPR016185 (10.7%)" "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (11.3%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily (11.2%) Pre-ATP-grasp domain superfamily (10.7%)" GLLQFHEYEDEVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR025393 (51.6%) IPR029044 (48.4%)" "Domain of unknown function DUF4301 (51.6%) Nucleotide-diphospho-sugar transferases (48.4%)" YMDECGAANFFGLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (13.5%) GO:0009098 (13.5%) GO:0009099 (13.5%)" "GO:0004084 (20.5%) GO:0052654 (4.9%) GO:0052655 (4.9%)" "isoleucine biosynthetic process (13.5%) L-leucine biosynthetic process (13.5%) L-valine biosynthetic process (13.5%)" "branched-chain-amino-acid transaminase activity (20.5%) L-leucine-2-oxoglutarate transaminase activity (4.9%) L-valine-2-oxoglutarate transaminase activity (4.9%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" EHLNEMFGLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0004467 (50%) membrane (50%) long-chain fatty acid-CoA ligase activity (50%) "IPR000873 (25.7%) IPR020845 (25.7%) IPR042099 (24.3%)" "AMP-dependent synthetase/ligase domain (25.7%) AMP-binding, conserved site (25.7%) ANL, N-terminal domain (24.3%)" LFTYHATPEDWEGFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024480 (50%) IPR036737 (50%)" "Domain of unknown function DUF3868 (50%) OmpA-like domain superfamily (50%)" ASWGQLGNENALGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.3%) IPR012910 (14.3%) IPR023996 (14.3%)" "Carboxypeptidase-like, regulatory domain superfamily (14.3%) TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%)" GLDPAGASFSDANVDRDNGLDMGAYPNPR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.3%) IPR012910 (13.3%) IPR023996 (13.3%)" "TonB-dependent receptor-like, beta-barrel (13.3%) TonB-dependent receptor, plug domain (13.3%) TonB-dependent outer membrane protein, SusC/RagA (13.3%)" SLAQELGPK Bacteria Bacteria 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) "GO:0006633 (31.3%) GO:0030497 (2.1%)" "GO:0004316 (31.3%) GO:0051287 (31.3%) GO:0016616 (2.1%)" "fatty acid biosynthetic process (31.3%) fatty acid elongation (2.1%)" "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (31.3%) NAD binding (31.3%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (2.1%)" "IPR002347 (17.8%) IPR020904 (17.8%) IPR011284 (16.7%)" "Short-chain dehydrogenase/reductase SDR (17.8%) Short-chain dehydrogenase/reductase, conserved site (17.8%) 3-oxoacyl-(acyl-carrier-protein) reductase (16.7%)" NDFSDASVLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GDDKTVCASLYSPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.1.3.3 (97%) 5.1.3.- (3%)" "aldose 1-epimerase (97%) Acting on carbohydrates and derivatives (3%)" "GO:0006006 (20.2%) GO:0033499 (20.2%)" GO:0005737 (20.2%) "GO:0004034 (20.2%) GO:0030246 (19%)" "glucose metabolic process (20.2%) galactose catabolic process via UDP-galactose, Leloir pathway (20.2%)" cytoplasm (20.2%) "aldose 1-epimerase activity (20.2%) carbohydrate binding (19%)" "IPR008183 (17.3%) IPR047215 (17.3%) IPR018052 (16.8%)" "Aldose 1-/Glucose-6-phosphate 1-epimerase (17.3%) Galactose mutarotase-like (17.3%) Aldose 1-epimerase, conserved site (16.8%)" DALVAFNLNDAVPDTEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25%) IPR035376 (25%) IPR038143 (25%)" "NigD-like N-terminal OB domain (25%) NigD-like, C-terminal domain (25%) NigD-like, C-terminal domain superfamily (25%)" FMLPYWNPYAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" EFLNTVLK root "2.1.1.190 (71.4%) 1.16.3.1 (14.3%) 3.4.24.- (14.3%)" "23S rRNA (uracil(1939)-C(5))-methyltransferase (71.4%) ferroxidase (14.3%) Metalloendopeptidases (14.3%)" "GO:0006412 (10.7%) GO:0006417 (9.8%) GO:0070475 (2.5%)" "GO:0015934 (10.7%) GO:0016020 (3.3%) GO:0005634 (1.6%)" "GO:0003735 (10.7%) GO:0019843 (10.7%) GO:0000049 (9.8%)" "translation (10.7%) regulation of translation (9.8%) rRNA base methylation (2.5%)" "large ribosomal subunit (10.7%) membrane (3.3%) nucleus (1.6%)" "structural constituent of ribosome (10.7%) rRNA binding (10.7%) tRNA binding (9.8%)" "IPR005878 (8.5%) IPR023673 (8.5%) IPR028364 (8.5%)" "Large ribosomal subunit protein uL1, bacteria (8.5%) Large ribosomal subunit protein uL1, conserved site (8.5%) Ribosomal protein uL1/ribosomal biogenesis protein (8.5%)" EFPEFDVR root 2.7.1.11 (100%) 6-phosphofructokinase (100%) "GO:0006002 (9.1%) GO:0030388 (9.1%) GO:0061621 (9.1%)" GO:0005945 (9.1%) "GO:0003872 (9.1%) GO:0005524 (9.1%) GO:0016208 (9.1%)" "fructose 6-phosphate metabolic process (9.1%) fructose 1,6-bisphosphate metabolic process (9.1%) canonical glycolysis (9.1%)" 6-phosphofructokinase complex (9.1%) "6-phosphofructokinase activity (9.1%) ATP binding (9.1%) AMP binding (9.1%)" "IPR000023 (16.9%) IPR015912 (16.9%) IPR022953 (16.9%)" "Phosphofructokinase domain (16.9%) Phosphofructokinase, conserved site (16.9%) ATP-dependent 6-phosphofructokinase (16.9%)" DLGLFEYKGETYCSVVPSPEMTAAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.5%) IPR013148 (14.5%) IPR013189 (14.5%)" "Glycoside hydrolase, family 32 (14.5%) Glycosyl hydrolase family 32, N-terminal (14.5%) Glycosyl hydrolase family 32, C-terminal (14.5%)" QVQEGKDLLYGVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0005886 (50%) GO:0016757 (50%) plasma membrane (50%) glycosyltransferase activity (50%) "IPR001173 (33.3%) IPR029044 (33.3%) IPR050256 (33.3%)" "Glycosyltransferase 2-like (33.3%) Nucleotide-diphospho-sugar transferases (33.3%) Glycosyltransferase 2 (33.3%)" ANVPGFRPGQAPMGMLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.8%) GO:0043335 (15.8%) GO:0051083 (15.8%)" GO:0005737 (5.4%) "GO:0003755 (15.8%) GO:0043022 (15.8%) GO:0044183 (15.8%)" "protein transport (15.8%) protein unfolding (15.8%) 'de novo' cotranslational protein folding (15.8%)" cytoplasm (5.4%) "peptidyl-prolyl cis-trans isomerase activity (15.8%) ribosome binding (15.8%) protein folding chaperone (15.8%)" "IPR005215 (19.1%) IPR008881 (19.1%) IPR027304 (18.4%)" "Trigger factor (19.1%) Trigger factor, ribosome-binding, bacterial (19.1%) Trigger factor/SurA domain superfamily (18.4%)" FFGGDLMAAEGGTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.1.182 (100%) lipid-A-disaccharide synthase (100%) GO:0009245 (25%) GO:0016020 (25%) "GO:0005543 (25%) GO:0008915 (25%)" lipid A biosynthetic process (25%) membrane (25%) "phospholipid binding (25%) lipid-A-disaccharide synthase activity (25%)" IPR003835 (100%) Glycosyl transferase, family 19 (100%) TSQPMMGLFKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0019843 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) rRNA binding (25%)" "IPR000597 (24.4%) IPR009000 (24.4%) IPR019926 (24.4%)" "Large ribosomal subunit protein uL3 (24.4%) Translation protein, beta-barrel domain superfamily (24.4%) Large ribosomal subunit protein uL3, conserved site (24.4%)" FNCPEFTSLCPLTGQPDFAELR Pseudomonadati Bacteria Pseudomonadati "1.7.1.13 (99.3%) 1.7.1.- (0.7%)" "preQ1 synthase (99.3%) With NAD(+) or NADP(+) as acceptor (0.7%)" "GO:0008616 (24.9%) GO:0006400 (24.1%)" "GO:0005737 (24.8%) GO:0005829 (0.1%)" "GO:0033739 (24.9%) GO:0016787 (1.1%) GO:0016491 (0.1%)" "tRNA queuosine(34) biosynthetic process (24.9%) tRNA modification (24.1%)" "cytoplasm (24.8%) cytosol (0.1%)" "preQ1 synthase activity (24.9%) hydrolase activity (1.1%) oxidoreductase activity (0.1%)" "IPR016856 (25%) IPR029500 (25%) IPR050084 (25%)" "NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 (25%) NADPH-dependent 7-cyano-7-deazaguanine reductase QueF (25%) NADPH-dependent 7-cyano-7-deazaguanine reductase (25%)" VLMEKPEGYVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006396 (14.3%) GO:0006402 (14.3%)" GO:0005829 (14.3%) "GO:0000175 (14.3%) GO:0000287 (14.3%) GO:0003723 (14.3%)" "RNA processing (14.3%) mRNA catabolic process (14.3%)" cytosol (14.3%) "3'-5'-RNA exonuclease activity (14.3%) magnesium ion binding (14.3%) RNA binding (14.3%)" "IPR001247 (7.8%) IPR003029 (7.8%) IPR004087 (7.8%)" "Exoribonuclease, phosphorolytic domain 1 (7.8%) S1 domain (7.8%) K Homology domain (7.8%)" NPFTFENPMHPLDQGFMGYSQNVSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR010870 (51.5%) IPR023614 (48.5%)" "Phosphate-selective porin O/P (51.5%) Porin domain superfamily (48.5%)" NQLDGAYVEVSTAAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.2.1.3 (100%) aconitate hydratase (100%) GO:0006099 (20.2%) GO:0005829 (20.2%) "GO:0003994 (20.2%) GO:0051539 (20.2%) GO:0046872 (19%)" tricarboxylic acid cycle (20.2%) cytosol (20.2%) "aconitate hydratase activity (20.2%) 4 iron, 4 sulfur cluster binding (20.2%) metal ion binding (19%)" "IPR000573 (11.6%) IPR050926 (11.6%) IPR001030 (11.2%)" "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain (11.6%) Aconitase/IPM Isomerase (11.6%) Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain (11.2%)" LYNYWSFLEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0005886 (50.8%) GO:0003755 (49.2%) plasma membrane (50.8%) peptidyl-prolyl cis-trans isomerase activity (49.2%) "IPR052029 (27%) IPR027304 (26.1%) IPR046357 (25.2%)" "Periplasmic chaperone PpiD (27%) Trigger factor/SurA domain superfamily (26.1%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.2%)" TSGSLYTTYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (34.2%) IPR018163 (32.9%) IPR027417 (32.9%)" "Phosphoribulokinase/uridine kinase (34.2%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (32.9%) P-loop containing nucleoside triphosphate hydrolase (32.9%)" AGVAVAPPTCYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.2%) IPR002469 (25.2%) IPR050278 (25.2%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.2%) Dipeptidylpeptidase IV, N-terminal domain (25.2%) Serine protease S9B/DPPIV (25.2%)" QLLDFNGSGLSLMELSHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.52 (100%) phosphoserine transaminase (100%) "GO:0006564 (20%) GO:0008615 (20%)" GO:0005737 (20%) "GO:0004648 (20%) GO:0030170 (20%)" "L-serine biosynthetic process (20%) pyridoxine biosynthetic process (20%)" cytoplasm (20%) "O-phospho-L-serine:2-oxoglutarate aminotransferase activity (20%) pyridoxal phosphate binding (20%)" "IPR000192 (19.3%) IPR022278 (19.3%) IPR015421 (18.6%)" "Aminotransferase class V domain (19.3%) Phosphoserine aminotransferase (19.3%) Pyridoxal phosphate-dependent transferase, major domain (18.6%)" LPQLPLLCDPSHLGGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.4.99.5 (100%) chorismate mutase (100%) GO:0046417 (50%) GO:0004106 (50%) chorismate metabolic process (50%) chorismate mutase activity (50%) "IPR002701 (17.9%) IPR006218 (17.9%) IPR052899 (17.9%)" "Chorismate mutase II, prokaryotic-type (17.9%) DAHP synthetase I/KDSA (17.9%) Class-I DAHP synthase (17.9%)" EGSLDLFVLDAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.2%) IPR011659 (14.2%) IPR012393 (14.2%)" "Tail specific protease (14.2%) WD40-like beta-propeller (14.2%) Tricorn protease (14.2%)" EQVYDFDR root GO:0006508 (5.7%) "GO:0005886 (43.3%) GO:0098552 (43.3%) GO:0016020 (1.4%)" GO:0008233 (5.7%) proteolysis (5.7%) "plasma membrane (43.3%) side of membrane (43.3%) membrane (1.4%)" peptidase activity (5.7%) "IPR001107 (20.6%) IPR036013 (20.6%) IPR050710 (20.6%)" "Band 7 domain (20.6%) Band 7/SPFH domain superfamily (20.6%) Band 7/mec-2 domain-containing protein (20.6%)" TLNWQPESTGTGR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0004822 (14.3%) GO:0005524 (14.3%)" isoleucyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) isoleucine-tRNA ligase activity (14.3%) ATP binding (14.3%)" "IPR002300 (12.5%) IPR002301 (12.5%) IPR013155 (12.5%)" "Aminoacyl-tRNA synthetase, class Ia (12.5%) Isoleucine-tRNA ligase (12.5%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.5%)" EYGEFLPANMR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" FPGLVYR root "3.1.13.4 (52.3%) 5.6.2.4 (22.7%) 1.3.1.74 (4.5%)" "poly(A)-specific ribonuclease (52.3%) DNA 3'-5' helicase (22.7%) 2-alkenal reductase [NAD(P)(+)] (4.5%)" "GO:0006352 (28.9%) GO:0042797 (0.9%) GO:0006367 (0.2%)" "GO:0005634 (4.2%) GO:0032991 (1%) GO:0005886 (0.6%)" "GO:0003677 (28.3%) GO:0003700 (24.1%) GO:0003743 (1.3%)" "DNA-templated transcription initiation (28.9%) tRNA transcription by RNA polymerase III (0.9%) transcription initiation at RNA polymerase II promoter (0.2%)" "nucleus (4.2%) protein-containing complex (1%) plasma membrane (0.6%)" "DNA binding (28.3%) DNA-binding transcription factor activity (24.1%) translation initiation factor activity (1.3%)" "IPR000814 (27%) IPR012295 (27%) IPR033711 (21.6%)" "TATA-box binding protein (27%) TBP domain superfamily (27%) TATA-box binding protein, archaea (21.6%)" EPVLWDLLENVMK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (16.8%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.4%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (16.8%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.4%)" "IPR000722 (9.2%) IPR006592 (9.2%) IPR007066 (9.2%)" "RNA polymerase, alpha subunit (9.2%) RNA polymerase, N-terminal (9.2%) RNA polymerase Rpb1, domain 3 (9.2%)" QLTPHPWDALDENLKVGDHVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" LGQEMGLK root "3.4.21.53 (37.5%) 3.4.24.- (25%) 2.4.-.- (12.5%)" "endopeptidase La (37.5%) Metalloendopeptidases (25%) Glycosyltransferases (12.5%)" "GO:0006508 (10.7%) GO:0008360 (10.6%) GO:0009252 (10.6%)" "GO:0030288 (10.6%) GO:0005886 (10.2%) GO:0016020 (0.9%)" "GO:0008658 (10.6%) GO:0008955 (10.6%) GO:0004180 (10.2%)" "proteolysis (10.7%) regulation of cell shape (10.6%) peptidoglycan biosynthetic process (10.6%)" "outer membrane-bounded periplasmic space (10.6%) plasma membrane (10.2%) membrane (0.9%)" "penicillin binding (10.6%) peptidoglycan glycosyltransferase activity (10.6%) carboxypeptidase activity (10.2%)" "IPR001460 (15.4%) IPR050396 (15.4%) IPR001264 (15.2%)" "Penicillin-binding protein, transpeptidase (15.4%) Glycosyltransferase 51/Transpeptidase (15.4%) Glycosyl transferase, family 51 (15.2%)" GYLGLEDNKPAALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.-.-.- (100%) Translocases (100%) GO:0022900 (19.5%) "GO:0005886 (19.5%) GO:0016020 (0.6%)" "GO:0009055 (20.1%) GO:0046872 (20.1%) GO:0051539 (20.1%)" electron transport chain (19.5%) "plasma membrane (19.5%) membrane (0.6%)" "electron transfer activity (20.1%) metal ion binding (20.1%) 4 iron, 4 sulfur cluster binding (20.1%)" "IPR010208 (14.7%) IPR011538 (14.7%) IPR017896 (14.2%)" "Ion-translocating oxidoreductase complex, subunit RnfC/RsxC (14.7%) NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain (14.7%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.2%)" LEGELTQYSQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0043165 (50%) GO:0019867 (50%) Gram-negative-bacterium-type cell outer membrane assembly (50%) outer membrane (50%) IPR007485 (100%) LPS-assembly lipoprotein LptE (100%) LDSLVTVVDALR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016787 (100%) hydrolase activity (100%) "IPR003495 (22.5%) IPR011629 (22.5%) IPR051927 (22.5%)" "CobW/HypB/UreG, nucleotide-binding domain (22.5%) Zinc chaperone CobW-like, C-terminal (22.5%) Zinc Chaperone and cDPG Synthetase (22.5%)" FANDLEEYGKVEQMPK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20%) "GO:0005829 (20%) GO:0016020 (20%)" "GO:0003743 (20%) GO:0043022 (20%)" ribosome disassembly (20%) "cytosol (20%) membrane (20%)" "translation initiation factor activity (20%) ribosome binding (20%)" "IPR001288 (17.1%) IPR019815 (17.1%) IPR019813 (16.6%)" "Translation initiation factor 3 (17.1%) Translation initiation factor 3, C-terminal (17.1%) Translation initiation factor 3, conserved site (16.6%)" AYSSYVEATAPFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae LNAVLTGVGGYVPDYLLNNEELSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.3.1.180 (100%) beta-ketoacyl-[acyl-carrier-protein] synthase III (100%) "GO:0006633 (20%) GO:0044550 (20%)" GO:0005737 (20%) "GO:0004315 (20%) GO:0033818 (20%)" "fatty acid biosynthetic process (20%) secondary metabolite biosynthetic process (20%)" cytoplasm (20%) "3-oxoacyl-[acyl-carrier-protein] synthase activity (20%) beta-ketoacyl-acyl-carrier-protein synthase III activity (20%)" "IPR004655 (25%) IPR013747 (25%) IPR013751 (25%)" "Beta-ketoacyl-[acyl-carrier-protein] synthase III (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, C-terminal (25%) Beta-ketoacyl-[acyl-carrier-protein] synthase III, N-terminal (25%)" QQLGEVLGEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) GO:0005886 (50%) "GO:0003755 (48.5%) GO:0016853 (1.5%)" plasma membrane (50%) "peptidyl-prolyl cis-trans isomerase activity (48.5%) isomerase activity (1.5%)" "IPR052029 (28.1%) IPR027304 (26.4%) IPR046357 (26.4%)" "Periplasmic chaperone PpiD (28.1%) Trigger factor/SurA domain superfamily (26.4%) Peptidyl-prolyl cis-trans isomerase domain superfamily (26.4%)" DVAVDWDK root "2.5.1.21 (28.6%) 3.2.1.- (28.6%) 3.2.1.3 (28.6%)" "squalene synthase (28.6%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (28.6%) glucan 1,4-alpha-glucosidase (28.6%)" "GO:0007165 (0.8%) GO:0016114 (0.8%)" GO:0000139 (0.8%) "GO:0030246 (49.2%) GO:0016787 (42.4%) GO:0004339 (1.7%)" "signal transduction (0.8%) terpenoid biosynthetic process (0.8%)" Golgi membrane (0.8%) "carbohydrate binding (49.2%) hydrolase activity (42.4%) glucan 1,4-alpha-glucosidase activity (1.7%)" "IPR019563 (14%) IPR029483 (14%) IPR052720 (14%)" "Glycosyl-hydrolase 97, catalytic domain (14%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14%) Glycosyl Hydrolase Family 97 (14%)" WLLLTEAPYNVK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" ALVLLGGDDSNTNACVLAEYYAAK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.3%) GO:0006002 (14.2%)" "GO:0005829 (14.3%) GO:0005737 (0.1%)" "GO:0003872 (14.3%) GO:0046872 (14.3%) GO:0047334 (14.2%)" "response to glucose (14.3%) fructose 6-phosphate metabolic process (14.2%)" "cytosol (14.3%) cytoplasm (0.1%)" "6-phosphofructokinase activity (14.3%) metal ion binding (14.3%) diphosphate-fructose-6-phosphate 1-phosphotransferase activity (14.2%)" "IPR000023 (25.2%) IPR022953 (25%) IPR035966 (25%)" "Phosphofructokinase domain (25.2%) ATP-dependent 6-phosphofructokinase (25%) Phosphofructokinase superfamily (25%)" VDGLANVNDESGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.6.2.2 (100%) DNA topoisomerase (ATP-hydrolyzing) (100%) "GO:0006265 (12.6%) GO:0006261 (12.3%)" "GO:0005737 (12.6%) GO:0009330 (12.6%) GO:0005694 (12.3%)" "GO:0003677 (12.6%) GO:0005524 (12.6%) GO:0034335 (12.3%)" "DNA topological change (12.6%) DNA-templated DNA replication (12.3%)" "cytoplasm (12.6%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (12.6%) chromosome (12.3%)" "DNA binding (12.6%) ATP binding (12.6%) DNA negative supercoiling activity (12.3%)" "IPR002205 (13%) IPR050220 (13%) IPR005743 (12.7%)" "DNA topoisomerase, type IIA, domain A (13%) Type II DNA Topoisomerases (13%) DNA gyrase, subunit A (12.7%)" GAVVALAEGGEGFATPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (25%) GO:0022627 (25%) "GO:0003729 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "mRNA binding (25%) structural constituent of ribosome (25%)" "IPR003029 (24.7%) IPR012340 (24.7%) IPR035104 (24.7%)" "S1 domain (24.7%) Nucleic acid-binding, OB-fold (24.7%) Ribosomal protein S1-like (24.7%)" SVDWLAECGGHVLNLLAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009098 (50%) GO:0003852 (50%) L-leucine biosynthetic process (50%) 2-isopropylmalate synthase activity (50%) "IPR000891 (14.6%) IPR002034 (14.6%) IPR013709 (14.6%)" "Pyruvate carboxyltransferase (14.6%) Alpha-isopropylmalate/homocitrate synthase, conserved site (14.6%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (14.6%)" VPLQCDDEFFSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0047617 (100%) fatty acyl-CoA hydrolase activity (100%) "IPR006684 (34.3%) IPR050563 (34.3%) IPR029069 (31.4%)" "Acyl-CoA thioester hydrolase YbgC/YbaW family (34.3%) 4-hydroxybenzoyl-CoA thioesterase (34.3%) HotDog domain superfamily (31.4%)" RPFTALMGGSK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.6%) GO:0006096 (16.6%)" GO:0005829 (16.6%) "GO:0004618 (16.6%) GO:0005524 (16.6%) GO:0043531 (16.6%)" "gluconeogenesis (16.6%) glycolytic process (16.6%)" cytosol (16.6%) "phosphoglycerate kinase activity (16.6%) ATP binding (16.6%) ADP binding (16.6%)" "IPR001576 (32.8%) IPR015824 (32.8%) IPR036043 (32.8%)" "Phosphoglycerate kinase (32.8%) Phosphoglycerate kinase, N-terminal (32.8%) Phosphoglycerate kinase superfamily (32.8%)" EFFQQNLSTELR root 6.3.1.1 (100%) aspartate--ammonia ligase (100%) "GO:0070981 (22.8%) GO:0006529 (2.2%)" GO:0005829 (25%) "GO:0004071 (25%) GO:0005524 (22.8%) GO:0000166 (2.2%)" "L-asparagine biosynthetic process (22.8%) obsolete asparagine biosynthetic process (2.2%)" cytosol (25%) "aspartate-ammonia ligase activity (25%) ATP binding (22.8%) nucleotide binding (2.2%)" "IPR004618 (34.4%) IPR006195 (32.8%) IPR045864 (32.8%)" "Aspartate--ammonia ligase (34.4%) Aminoacyl-tRNA synthetase, class II (32.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (32.8%)" TQVNFNASLGYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (28.6%) GO:0009279 (71.4%) iron ion transport (28.6%) cell outer membrane (71.4%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" LLGDDEHGWDDNGVFNFEGGCYAK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.4%) GO:0005829 (17.4%) "GO:0004612 (17.4%) GO:0005524 (17.4%) GO:0046872 (17.2%)" gluconeogenesis (17.4%) cytosol (17.4%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.4%) ATP binding (17.4%) metal ion binding (17.2%)" "IPR001272 (25.1%) IPR015994 (25.1%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.1%) Phosphoenolpyruvate carboxykinase (ATP), conserved site (25.1%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" KNDLAVNPEDYWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (10%) GO:0009279 (90%) iron ion transport (10%) cell outer membrane (90%) "IPR012910 (14.3%) IPR023996 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" LFGGLLAR root "2.1.2.3 (44.6%) 3.5.4.10 (42.9%) 1.1.1.169 (2.7%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (44.6%) IMP cyclohydrolase (42.9%) 2-dehydropantoate 2-reductase (2.7%)" "GO:0006189 (14.4%) GO:0005975 (2%) GO:0006605 (1.5%)" "GO:0005829 (15.6%) GO:0005886 (11.1%) GO:0016020 (2.5%)" "GO:0003937 (14.4%) GO:0004643 (14.4%) GO:0022857 (1.7%)" "'de novo' IMP biosynthetic process (14.4%) carbohydrate metabolic process (2%) protein targeting (1.5%)" "cytosol (15.6%) plasma membrane (11.1%) membrane (2.5%)" "IMP cyclohydrolase activity (14.4%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (14.4%) transmembrane transporter activity (1.7%)" "IPR002695 (11.7%) IPR011607 (11.7%) IPR036914 (11.7%)" "Bifunctional purine biosynthesis protein PurH-like (11.7%) Methylglyoxal synthase-like domain (11.7%) Methylglyoxal synthase-like domain superfamily (11.7%)" VWKPLEGLQYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (13.2%) IPR023996 (13.2%) IPR023997 (13.2%)" "TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (13.2%)" WVNQEAGVLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (55.6%) IPR008160 (44.4%)" "Domain of unknown function DUF4988 (55.6%) Collagen triple helix repeat (44.4%)" VDGKPLAEMGLSDER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006108 (31.4%) GO:0006089 (2.9%)" "GO:0016615 (31.4%) GO:0016616 (31.4%) GO:0004459 (2.9%)" "malate metabolic process (31.4%) lactate metabolic process (2.9%)" "malate dehydrogenase activity (31.4%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (31.4%) L-lactate dehydrogenase (NAD+) activity (2.9%)" "IPR001236 (16.9%) IPR001557 (16.9%) IPR015955 (16.9%)" "Lactate/malate dehydrogenase, N-terminal (16.9%) L-lactate/malate dehydrogenase (16.9%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.9%)" MGAQTAEANLNAGLAAAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.95 (73%) 1.1.1.290 (16.2%) 1.1.1.81 (8.1%)" "phosphoglycerate dehydrogenase (73%) 4-phosphoerythronate dehydrogenase (16.2%) hydroxypyruvate reductase (8.1%)" "GO:0051287 (49.7%) GO:0016616 (39.4%) GO:0004617 (7.6%)" "NAD binding (49.7%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (39.4%) phosphoglycerate dehydrogenase activity (7.6%)" "IPR006140 (29.4%) IPR036291 (29.2%) IPR006139 (29%)" "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (29.4%) NAD(P)-binding domain superfamily (29.2%) D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (29%)" VPELLLSGNEAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.228 (98.5%) 2.1.1.- (1.5%)" "tRNA (guanine(37)-N(1))-methyltransferase (98.5%) Methyltransferases (1.5%)" "GO:0002939 (32.8%) GO:0008033 (0.5%) GO:0032259 (0.5%)" GO:0005829 (32.8%) GO:0052906 (33.3%) "tRNA N1-guanine methylation (32.8%) tRNA processing (0.5%) methylation (0.5%)" cytosol (32.8%) tRNA (guanine(37)-N1)-methyltransferase activity (33.3%) "IPR016009 (20.3%) IPR002649 (20%) IPR023148 (20%)" "tRNA methyltransferase TRMD/TRM10-type domain (20.3%) tRNA (guanine-N1-)-methyltransferase TrmD (20%) tRNA (guanine-N(1)-)-methyltransferase, C-terminal domain superfamily (20%)" TVGAMSPEELFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (50%) GO:0035673 (50%) membrane (50%) oligopeptide transmembrane transporter activity (50%) "IPR004813 (33.3%) IPR004814 (33.3%) IPR045035 (33.3%)" "Oligopeptide transporter, OPT superfamily (33.3%) Oligopeptide transporter OPT (33.3%) Metal-nicotianamine transporter YSL-like (33.3%)" LSANDNALAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" GPGMFDLSAFLGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.17 (100%) glutamate--tRNA ligase (100%) GO:0006424 (16.7%) GO:0005829 (16.7%) "GO:0004818 (16.7%) GO:0005524 (16.7%) GO:0008270 (16.7%)" glutamyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "glutamate-tRNA ligase activity (16.7%) ATP binding (16.7%) zinc ion binding (16.7%)" "IPR004527 (10%) IPR020058 (10%) IPR033910 (10%)" "Glutamate-tRNA ligase, bacterial/mitochondrial (10%) Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain (10%) Glutamyl-tRNA synthetase (10%)" LLELYGPESSGK root "6.3.1.2 (66.7%) 2.7.4.25 (16.7%) 3.6.3.8 (16.7%)" "glutamine synthetase (66.7%) (d)CMP kinase (16.7%) Transferred entry: 7.2.2.10 (16.7%)" "GO:0006281 (13.8%) GO:0006310 (13.8%) GO:0009432 (9.1%)" "GO:0005829 (13.7%) GO:0005737 (0.1%) GO:0016020 (0%)" "GO:0003697 (13.8%) GO:0005524 (13.8%) GO:0140664 (13.8%)" "DNA repair (13.8%) DNA recombination (13.8%) SOS response (9.1%)" "cytosol (13.7%) cytoplasm (0.1%) membrane (0%)" "single-stranded DNA binding (13.8%) ATP binding (13.8%) ATP-dependent DNA damage sensor activity (13.8%)" "IPR013765 (13.9%) IPR049428 (13.9%) IPR020588 (13.9%)" "DNA recombination and repair protein RecA (13.9%) RecA-like, N-terminal (13.9%) DNA recombination and repair protein RecA-like, ATP-binding domain (13.9%)" TEEVNLGLTK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.4.1.13 (100%) glutamate synthase (NADPH) (100%) "GO:0051536 (49.5%) GO:0016491 (47.5%) GO:0004355 (3%)" "iron-sulfur cluster binding (49.5%) oxidoreductase activity (47.5%) glutamate synthase (NADPH) activity (3%)" "IPR017927 (11.2%) IPR019480 (11.2%) IPR023753 (11.2%)" "FAD-binding domain, ferredoxin reductase-type (11.2%) Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain (11.2%) FAD/NAD(P)-binding domain (11.2%)" LPGTLDPELVELAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006094 (33.3%) GO:0005737 (33.3%) GO:0004736 (33.3%) gluconeogenesis (33.3%) cytoplasm (33.3%) pyruvate carboxylase activity (33.3%) "IPR003379 (22%) IPR000891 (21.1%) IPR055268 (21.1%)" "Carboxylase, conserved domain (22%) Pyruvate carboxyltransferase (21.1%) Pyruvate carboxylase-like (21.1%)" LGGLVPALLQDAVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "3.5.4.19 (50%) 3.6.1.31 (50%)" "phosphoribosyl-AMP cyclohydrolase (50%) phosphoribosyl-ATP diphosphatase (50%)" GO:0000105 (20%) GO:0005737 (20%) "GO:0004635 (20%) GO:0004636 (20%) GO:0005524 (20%)" L-histidine biosynthetic process (20%) cytoplasm (20%) "phosphoribosyl-AMP cyclohydrolase activity (20%) phosphoribosyl-ATP diphosphatase activity (20%) ATP binding (20%)" "IPR002496 (20%) IPR008179 (20%) IPR021130 (20%)" "Phosphoribosyl-AMP cyclohydrolase domain (20%) Phosphoribosyl-ATP pyrophosphohydrolase (20%) Phosphoribosyl-ATP pyrophosphohydrolase-like (20%)" VTVNVVNASLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (13.4%) IPR012910 (13.4%) IPR023996 (13.4%)" "Carboxypeptidase-like, regulatory domain superfamily (13.4%) TonB-dependent receptor, plug domain (13.4%) TonB-dependent outer membrane protein, SusC/RagA (13.4%)" YYVSGGMMDQDGTLLGSNFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (14.4%) IPR012910 (14.4%) IPR023996 (14.4%)" "Carboxypeptidase-like, regulatory domain superfamily (14.4%) TonB-dependent receptor, plug domain (14.4%) TonB-dependent outer membrane protein, SusC/RagA (14.4%)" GQQTELGAVNVMTGLYTGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.3%) GO:0005829 (17.3%) "GO:0004612 (17.3%) GO:0005524 (17.3%) GO:0046872 (17.3%)" gluconeogenesis (17.3%) cytosol (17.3%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.3%) ATP binding (17.3%) metal ion binding (17.3%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" DCQDQFLDAMR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (17.8%) GO:0045259 (17.8%)" "GO:0005524 (17.8%) GO:0043531 (17.8%) GO:0046933 (17.8%)" "plasma membrane (17.8%) proton-transporting ATP synthase complex (17.8%)" "ATP binding (17.8%) ADP binding (17.8%) proton-transporting ATP synthase activity, rotational mechanism (17.8%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" SLMDNLFLYDGTEHKHEAQQPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006412 (20%) GO:0017148 (20%)" GO:0022625 (20%) "GO:0003729 (20%) GO:0003735 (20%)" "translation (20%) negative regulation of translation (20%)" cytosolic large ribosomal subunit (20%) "mRNA binding (20%) structural constituent of ribosome (20%)" "IPR005822 (25%) IPR005823 (25%) IPR023563 (25%)" "Large ribosomal subunit protein uL13 (25%) Large ribosomal subunit protein uL13, bacteria (25%) Large ribosomal subunit protein uL13, conserved site (25%)" LVNPDLSYAGTPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0071709 (49.3%) "GO:0009279 (42.3%) GO:0019867 (8.5%)" membrane assembly (49.3%) "cell outer membrane (42.3%) outer membrane (8.5%)" "IPR010827 (26.3%) IPR034746 (26.3%) IPR023707 (25.5%)" "POTRA domain, BamA/TamA-like (26.3%) POTRA domain (26.3%) Outer membrane protein assembly factor BamA (25.5%)" CLPELLEGHDVLGVAQTGTGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0005829 (20%) "GO:0003676 (20%) GO:0003724 (20%) GO:0005524 (20%)" cytosol (20%) "nucleic acid binding (20%) RNA helicase activity (20%) ATP binding (20%)" "IPR001650 (14.4%) IPR011545 (14.4%) IPR014001 (14.4%)" "Helicase, C-terminal domain-like (14.4%) DEAD/DEAH-box helicase domain (14.4%) Helicase superfamily 1/2, ATP-binding domain (14.4%)" EVSEFLNR root 2.7.13.3 (100%) histidine kinase (100%) "GO:0006813 (18.3%) GO:0006935 (1.7%) GO:0007165 (1.7%)" "GO:0005886 (33%) GO:0005737 (1.7%) GO:0016020 (1.7%)" "GO:0008324 (18.3%) GO:0140359 (13%) GO:0003723 (1.7%)" "potassium ion transport (18.3%) chemotaxis (1.7%) signal transduction (1.7%)" "plasma membrane (33%) cytoplasm (1.7%) membrane (1.7%)" "monoatomic cation transmembrane transporter activity (18.3%) ABC-type transporter activity (13%) RNA binding (1.7%)" "IPR006037 (13.5%) IPR006512 (13.5%) IPR050144 (13.5%)" "Regulator of K+ conductance, C-terminal (13.5%) YidE/YbjL duplication (13.5%) AAE Transporter (13.5%)" SADFGQLLNAAGALK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) IPR005017 (100%) Outer membrane protein transport protein (OMPP1/FadL/TodX) (100%) YVMFDGK root 2.1.2.2 (100%) phosphoribosylglycinamide formyltransferase 1 (100%) "GO:0006811 (7.7%) GO:0006189 (0.5%)" "GO:0009279 (7.7%) GO:0046930 (7.7%) GO:0005829 (0.5%)" "GO:0008990 (21%) GO:0070043 (21%) GO:0003723 (20.5%)" "monoatomic ion transport (7.7%) 'de novo' IMP biosynthetic process (0.5%)" "cell outer membrane (7.7%) pore complex (7.7%) cytosol (0.5%)" "rRNA (guanine-N2-)-methyltransferase activity (21%) rRNA (guanine-N7-)-methyltransferase activity (21%) RNA binding (20.5%)" "IPR000241 (11.4%) IPR002052 (11.4%) IPR004114 (11.1%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (11.4%) DNA methylase, N-6 adenine-specific, conserved site (11.4%) THUMP domain (11.1%)" LLAQAELTK root "GO:0005980 (18.8%) GO:0006355 (3.1%) GO:0016477 (3.1%)" "GO:0005737 (3.1%) GO:0005886 (3.1%) GO:0016020 (1.6%)" "GO:0004134 (18.8%) GO:0004135 (18.8%) GO:0000976 (6.3%)" "glycogen catabolic process (18.8%) regulation of DNA-templated transcription (3.1%) cell migration (3.1%)" "cytoplasm (3.1%) plasma membrane (3.1%) membrane (1.6%)" "4-alpha-glucanotransferase activity (18.8%) amylo-alpha-1,6-glucosidase activity (18.8%) transcription cis-regulatory region binding (6.3%)" "IPR008928 (13%) IPR010401 (13%) IPR012341 (13%)" "Six-hairpin glycosidase superfamily (13%) Glycogen debranching enzyme (13%) Six-hairpin glycosidase-like superfamily (13%)" NWYLPLNK root 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002547 (8.3%) IPR004495 (8.3%) IPR009080 (8.3%)" "tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%) Aminoacyl-tRNA synthetase, class Ia, anticodon-binding (8.3%)" KVESYLAVK Pseudomonadati Bacteria Pseudomonadati GO:0005975 (37.5%) GO:0005737 (12.5%) "GO:0004553 (37.5%) GO:0005085 (12.5%)" carbohydrate metabolic process (37.5%) cytoplasm (12.5%) "hydrolase activity, hydrolyzing O-glycosyl compounds (37.5%) guanyl-nucleotide exchange factor activity (12.5%)" "IPR026444 (56.3%) IPR013783 (7.8%) IPR013320 (6.3%)" "Secretion system, C-terminal sorting domain (56.3%) Immunoglobulin-like fold (7.8%) Concanavalin A-like lectin/glucanase domain superfamily (6.3%)" LAEVYYLAAEAEAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.1%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.1%)" GLLDATLEGNDFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NNPGYDVNPQFSADGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0004252 (50%) proteolysis (50%) serine-type endopeptidase activity (50%) "IPR011659 (21.6%) IPR001375 (20.9%) IPR011042 (19.6%)" "WD40-like beta-propeller (21.6%) Peptidase S9, prolyl oligopeptidase, catalytic domain (20.9%) Six-bladed beta-propeller, TolB-like (19.6%)" LFSSEFSYQYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036942 (100%) TonB-dependent receptor-like, beta-barrel domain superfamily (100%) LLDQYAQFVEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0017038 (50%) GO:0005886 (50%) protein import (50%) plasma membrane (50%) "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" VYLSGQNLLTLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.1%) IPR023996 (13.1%) IPR036942 (13.1%)" "TonB-dependent receptor-like, beta-barrel (13.1%) TonB-dependent outer membrane protein, SusC/RagA (13.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (13.1%)" FAGFSYLETWGNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0016747 (95.8%) GO:0016740 (4.2%)" "acyltransferase activity, transferring groups other than amino-acyl groups (95.8%) transferase activity (4.2%)" "IPR016181 (55.9%) IPR000182 (39%) IPR007569 (1.7%)" "Acyl-CoA N-acyltransferase (55.9%) GNAT domain (39%) Domain of unknown function DUF559 (1.7%)" DTYAEASQWEEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.5%) GO:0005829 (17.5%) "GO:0004612 (17.5%) GO:0005524 (17.5%) GO:0046872 (17.5%)" gluconeogenesis (17.5%) cytosol (17.5%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.5%) ATP binding (17.5%) metal ion binding (17.5%)" "IPR001272 (25%) IPR008210 (25%) IPR013035 (25%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25%) Phosphoenolpyruvate carboxykinase, N-terminal (25%) Phosphoenolpyruvate carboxykinase, C-terminal (25%)" KAADQPAANFVQSSLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.6%) IPR033985 (33.3%) IPR011990 (32.1%)" "RagB/SusD domain (34.6%) SusD-like, N-terminal (33.3%) Tetratricopeptide-like helical domain superfamily (32.1%)" AVTNVVAECASR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri NDGELGNTWYVPGYGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae IPR046111 (100%) Protein of unknown function DUF6048 (100%) EGATLEKDEVCQLTTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR013728 (50%) IPR040580 (50%)" "BT_3987-like, N-terminal domain (50%) Domain of unknown function DUF5627 (50%)" HYWFPLPLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (33.3%) IPR011990 (31.8%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (33.3%) Tetratricopeptide-like helical domain superfamily (31.8%)" GLHDVQLSDYWLEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VLPVVLTYYTDK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0070180 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) large ribosomal subunit rRNA binding (25%)" "IPR000911 (14.6%) IPR020783 (14.6%) IPR036769 (14.6%)" "Ribosomal protein uL11 (14.6%) Large ribosomal subunit protein uL11, C-terminal (14.6%) Large ribosomal subunit protein uL11, C-terminal domain superfamily (14.6%)" DGFVQLANLFEETAANEK Pseudomonadati Bacteria Pseudomonadati "GO:0005506 (46.7%) GO:0016491 (46.7%) GO:0016692 (3.3%)" "iron ion binding (46.7%) oxidoreductase activity (46.7%) NADH peroxidase activity (3.3%)" "IPR003251 (14.7%) IPR009040 (14.7%) IPR048574 (14.7%)" "Rubrerythrin, diiron-binding domain (14.7%) Ferritin-like diiron domain (14.7%) Rubrerythrin, rubredoxin-like domain (14.7%)" DDAQLTPNYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" VLNLASNTFNENETSYYHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) IPR018580 (100%) Uncharacterised protein family YfhO (100%) VALPMDATLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0016020 (100%) membrane (100%) IPR025324 (100%) Protein of unknown function DUF4230 (100%) VSNALLTTELSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.5%) GO:0009279 (35%) GO:0015344 (32.5%) siderophore transmembrane transport (32.5%) cell outer membrane (35%) siderophore uptake transmembrane transporter activity (32.5%) "IPR036942 (50%) IPR039426 (48.1%) IPR057601 (1.9%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (48.1%) TonB-dependent transporter Oar-like, beta-barrel domain (1.9%)" SLEVSNHVSPLAAVPFVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.4.25 (100%) (d)CMP kinase (100%) "GO:0006220 (19.2%) GO:0015949 (19.2%)" GO:0005829 (19.2%) "GO:0005524 (19.2%) GO:0036431 (19.2%) GO:0036430 (4.1%)" "pyrimidine nucleotide metabolic process (19.2%) nucleobase-containing small molecule interconversion (19.2%)" cytosol (19.2%) "ATP binding (19.2%) dCMP kinase activity (19.2%) CMP kinase activity (4.1%)" "IPR003136 (33.3%) IPR011994 (33.3%) IPR027417 (33.3%)" "Cytidylate kinase (33.3%) Cytidylate kinase domain (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" ANKEPDNVQYTYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR000223 (25.5%) IPR019533 (25.5%) IPR019758 (25.5%)" "Peptidase S26A, signal peptidase I (25.5%) Peptidase S26 (25.5%) Peptidase S26A, signal peptidase I, conserved site (25.5%)" ACLAAGTQPDFFVYPGEPHNMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (62.5%) 3.4.14.12 (25%) 3.4.14.5 (12.5%)" "Acting on peptide bonds (peptidases) (62.5%) Xaa-Xaa-Pro tripeptidyl-peptidase (25%) dipeptidyl-peptidase IV (12.5%)" GO:0006508 (33.2%) "GO:0008236 (33.2%) GO:0008239 (33.2%) GO:0004177 (0.5%)" proteolysis (33.2%) "serine-type peptidase activity (33.2%) dipeptidyl-peptidase activity (33.2%) aminopeptidase activity (0.5%)" "IPR001375 (25.3%) IPR002469 (25.3%) IPR050278 (25.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.3%) Dipeptidylpeptidase IV, N-terminal domain (25.3%) Serine protease S9B/DPPIV (25.3%)" LYAYLSDGAVEEELSQGVGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.2.1.1 (94.1%) 1.2.4.4 (2.9%) 2.2.1.- (2.9%)" "transketolase (94.1%) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (2.9%) Transketolases and transaldolases (2.9%)" GO:0006098 (25%) GO:0005829 (25%) "GO:0004802 (25%) GO:0046872 (24.2%) GO:0003863 (0.8%)" pentose-phosphate shunt (25%) cytosol (25%) "transketolase activity (25%) metal ion binding (24.2%) branched-chain 2-oxo acid dehydrogenase activity (0.8%)" "IPR005474 (12.7%) IPR029061 (12.7%) IPR033247 (12.7%)" "Transketolase, N-terminal (12.7%) Thiamin diphosphate-binding fold (12.7%) Transketolase family (12.7%)" ENYPNLPLEALANAEGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0016485 (25%) GO:0005886 (25%) "GO:0004222 (25%) GO:0046872 (25%)" protein processing (25%) plasma membrane (25%) "metalloendopeptidase activity (25%) metal ion binding (25%)" "IPR000718 (20.5%) IPR008753 (20.5%) IPR018497 (20.5%)" "Peptidase M13 (20.5%) Peptidase M13, N-terminal domain (20.5%) Peptidase M13, C-terminal domain (20.5%)" GDTDGSVEALSDSFLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005737 (25.2%) "GO:0003743 (25.2%) GO:0005525 (25.2%) GO:0003924 (24.4%)" cytoplasm (25.2%) "translation initiation factor activity (25.2%) GTP binding (25.2%) GTPase activity (24.4%)" "IPR015760 (8.6%) IPR023115 (8.6%) IPR044145 (8.6%)" "Translation initiation factor IF- 2 (8.6%) Translation initiation factor IF- 2, domain 3 (8.6%) Translation initiation factor IF-2, domain II (8.6%)" SLFGFDYMTNNLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (12.9%) IPR012910 (12.9%) IPR023996 (12.9%)" "TonB-dependent receptor-like, beta-barrel (12.9%) TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%)" GTLAGREEWYTSEEAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006826 (11.1%) GO:0009279 (88.9%) iron ion transport (11.1%) cell outer membrane (88.9%) "IPR012910 (14.2%) IPR023996 (14.2%) IPR023997 (14.2%)" "TonB-dependent receptor, plug domain (14.2%) TonB-dependent outer membrane protein, SusC/RagA (14.2%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.2%)" FSDTDWLDELSR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" SLTSSPVVLSGLDGDSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0004557 (100%) alpha-galactosidase activity (100%) "IPR033427 (35.5%) IPR011050 (32.3%) IPR012334 (12.9%)" "Domain of unknown function DUF5123 (35.5%) Pectin lyase fold/virulence factor (32.3%) Pectin lyase fold (12.9%)" GLKGGHSGLELNEGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25%) GO:0005829 (25%) "GO:0046872 (25%) GO:0070573 (25%)" proteolysis (25%) cytosol (25%) "metal ion binding (25%) metallodipeptidase activity (25%)" "IPR001160 (33%) IPR002933 (33%) IPR011650 (33%)" "Peptidase M20C, Xaa-His dipeptidase (33%) Peptidase M20 (33%) Peptidase M20, dimerisation domain (33%)" YADGAFTNEDLYAVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (55.6%) IPR008160 (44.4%)" "Domain of unknown function DUF4988 (55.6%) Collagen triple helix repeat (44.4%)" LNQSLQVMEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (25%) GO:0005829 (25%) "GO:0003723 (25%) GO:0008859 (25%)" mRNA catabolic process (25%) cytosol (25%) "RNA binding (25%) exoribonuclease II activity (25%)" "IPR001900 (12.6%) IPR003029 (12.6%) IPR004476 (12.6%)" "Ribonuclease II/R (12.6%) S1 domain (12.6%) Ribonuclease II/ribonuclease R (12.6%)" LGKDGLEVDYAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (50%) GO:0008422 (50%) carbohydrate metabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR019800 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Glycoside hydrolase, family 3, active site (11.4%)" ASADAEGEATPAYGR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri TSGFYSLVEFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (16.7%) "GO:0005737 (16.7%) GO:0005840 (16.7%) GO:1990904 (16.7%)" "GO:0003735 (16.7%) GO:0070181 (16.7%)" translation (16.7%) "cytoplasm (16.7%) ribosome (16.7%) ribonucleoprotein complex (16.7%)" "structural constituent of ribosome (16.7%) small ribosomal subunit rRNA binding (16.7%)" "IPR000529 (25%) IPR014717 (25%) IPR020814 (25%)" "Small ribosomal subunit protein bS6 (25%) Translation elongation factor EF1B/small ribosomal subunit protein bS6 (25%) Small ribosomal subunit protein bS6, plastid/chloroplast (25%)" VFGGWSNTLSYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" LLQDLLVVR root 2.7.11.1 (100%) non-specific serine/threonine protein kinase (100%) GO:0006281 (2.4%) GO:0005634 (2.4%) "GO:0004180 (87.8%) GO:0004674 (2.4%) GO:0005524 (2.4%)" DNA repair (2.4%) nucleus (2.4%) "carboxypeptidase activity (87.8%) protein serine/threonine kinase activity (2.4%) ATP binding (2.4%)" "IPR043741 (44.7%) IPR008969 (42.4%) IPR000403 (1.2%)" "Family of unknown function DUF5686 (44.7%) Carboxypeptidase-like, regulatory domain superfamily (42.4%) Phosphatidylinositol 3-/4-kinase, catalytic domain (1.2%)" VKEANDQAVHDFLAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016627 (50.6%) GO:0050660 (49.4%)" "oxidoreductase activity, acting on the CH-CH group of donors (50.6%) flavin adenine dinucleotide binding (49.4%)" "IPR009075 (10.3%) IPR020964 (10.3%) IPR052166 (10.3%)" "Acyl-CoA dehydrogenase/oxidase, C-terminal (10.3%) Acyl-CoA dehydrogenase, C-terminal (10.3%) Diverse substrate specificity acyl-CoA dehydrogenase (10.3%)" FCTFTEPTADR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" TVCKPSHLGLELAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0030246 (50.6%) GO:0016787 (49.4%)" "carbohydrate binding (50.6%) hydrolase activity (49.4%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" QMANSSLQADQLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri KYVEDVEFYAEDAGR Bacteria Bacteria 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (24.1%) GO:0005737 (17%) "GO:0003852 (24.1%) GO:0003985 (17%) GO:0030145 (17%)" L-leucine biosynthetic process (24.1%) cytoplasm (17%) "2-isopropylmalate synthase activity (24.1%) acetyl-CoA C-acetyltransferase activity (17%) manganese ion binding (17%)" "IPR000891 (13.9%) IPR002034 (13.9%) IPR013785 (13.9%)" "Pyruvate carboxyltransferase (13.9%) Alpha-isopropylmalate/homocitrate synthase, conserved site (13.9%) Aldolase-type TIM barrel (13.9%)" KDNASNEALAEQEAER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (25.2%) "GO:0005525 (25.2%) GO:0015093 (25.2%) GO:0046914 (24.4%)" plasma membrane (25.2%) "GTP binding (25.2%) ferrous iron transmembrane transporter activity (25.2%) transition metal ion binding (24.4%)" "IPR005225 (9.4%) IPR030389 (9.4%) IPR050860 (9.4%)" "Small GTP-binding domain (9.4%) FeoB-type guanine nucleotide-binding (G) domain (9.4%) Fe(2+) Transporter FeoB GTPase (9.4%)" GLSQDEADKLFER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.13.3 (100%) histidine kinase (100%) GO:0016020 (19%) "GO:0000155 (20.3%) GO:0003700 (20.3%) GO:0005524 (20.3%)" membrane (19%) "phosphorelay sensor kinase activity (20.3%) DNA-binding transcription factor activity (20.3%) ATP binding (20.3%)" "IPR001789 (7.8%) IPR003594 (7.8%) IPR003661 (7.8%)" "Signal transduction response regulator, receiver domain (7.8%) Histidine kinase/HSP90-like ATPase domain (7.8%) Signal transduction histidine kinase, dimerisation/phosphoacceptor domain (7.8%)" AWGQVPTTKPMVDFLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0000272 (18.2%) GO:0006080 (18.2%) GO:0030245 (11.4%)" "GO:0005576 (11.4%) GO:0009986 (11.4%)" "GO:0016985 (18.2%) GO:0008422 (11.4%)" "polysaccharide catabolic process (18.2%) substituted mannan metabolic process (18.2%) cellulose catabolic process (11.4%)" "extracellular region (11.4%) cell surface (11.4%)" "mannan endo-1,4-beta-mannosidase activity (18.2%) beta-glucosidase activity (11.4%)" "IPR001547 (25%) IPR017853 (25%) IPR022790 (25%)" "Glycoside hydrolase, family 5 (25%) Glycoside hydrolase superfamily (25%) Glycosyl hydrolase family 26 domain (25%)" FTQTWLK root "2.4.1.1 (66.7%) 2.3.2.27 (33.3%)" "glycogen phosphorylase (66.7%) RING-type E3 ubiquitin transferase (33.3%)" "GO:0005975 (28.1%) GO:0030258 (1.4%) GO:0006511 (0.7%)" "GO:0016020 (2.9%) GO:0005886 (2.2%) GO:0000325 (0.7%)" "GO:0030170 (27.3%) GO:0008184 (26.6%) GO:0005524 (2.2%)" "carbohydrate metabolic process (28.1%) lipid modification (1.4%) ubiquitin-dependent protein catabolic process (0.7%)" "membrane (2.9%) plasma membrane (2.2%) plant-type vacuole (0.7%)" "pyridoxal phosphate binding (27.3%) glycogen phosphorylase activity (26.6%) ATP binding (2.2%)" "IPR011834 (22.5%) IPR052182 (22.5%) IPR000811 (21.9%)" "Alpha-glucan phosphorylase (22.5%) Glycogen_Maltodextrin_Phosphorylase (22.5%) Glycosyl transferase, family 35 (21.9%)" NYYFPVPDDTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" SWVETWGFDAFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005886 (33.3%) "GO:0015212 (33.3%) GO:0015213 (33.3%)" plasma membrane (33.3%) "cytidine transmembrane transporter activity (33.3%) uridine transmembrane transporter activity (33.3%)" "IPR004740 (33.9%) IPR020846 (33.9%) IPR036259 (32.2%)" "Nucleoside:H+ symporter (33.9%) Major facilitator superfamily domain (33.9%) MFS transporter superfamily (32.2%)" NPGNFANAAPFLYSGDGSLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0044718 (32.9%) GO:0009279 (34.1%) GO:0015344 (32.9%) siderophore transmembrane transport (32.9%) cell outer membrane (34.1%) siderophore uptake transmembrane transporter activity (32.9%) "IPR036942 (50%) IPR039426 (50%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (50%) TonB-dependent receptor-like (50%)" GTTNLAESLQGSVPGVNLTQSGSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" ATLAPTEGENVDDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR041218 (26.5%) IPR049280 (26.5%) IPR049281 (23.5%)" "Domain of unknown function DUF5606 (26.5%) Domain of unknown function DUF6852 (26.5%) BVU_3817-like, C-terminal domain superfamily (23.5%)" ASGHVDAFNDPLLDNR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.7%) GO:0015966 (12.2%) GO:0044281 (0.2%)" "GO:0005737 (12.7%) GO:0070062 (12.2%) GO:1990742 (12.2%)" "GO:0004820 (12.7%) GO:0005524 (12.5%) GO:0004081 (12.2%)" "glycyl-tRNA aminoacylation (12.7%) diadenosine tetraphosphate biosynthetic process (12.2%) small molecule metabolic process (0.2%)" "cytoplasm (12.7%) extracellular exosome (12.2%) microvesicle (12.2%)" "glycine-tRNA ligase activity (12.7%) ATP binding (12.5%) bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.2%)" "IPR027031 (11.3%) IPR045864 (11.2%) IPR002314 (11.1%)" "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.3%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (11.2%) Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.1%)" LTHAEFVNPDGSYAAVLLNEGDEAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006680 (33.3%) GO:0016020 (33.3%) GO:0004348 (33.3%) glucosylceramide catabolic process (33.3%) membrane (33.3%) glucosylceramidase activity (33.3%) "IPR001139 (20.8%) IPR033452 (20.8%) IPR017853 (19.8%)" "Glycoside hydrolase family 30 (20.8%) Glycosyl hydrolase family 30, beta sandwich domain (20.8%) Glycoside hydrolase superfamily (19.8%)" VDWTSLATNEDFSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002035 (34.3%) IPR002881 (34.3%) IPR036465 (31.4%)" "von Willebrand factor, type A (34.3%) Domain of unknown function DUF58 (34.3%) von Willebrand factor A-like domain superfamily (31.4%)" VVDYTDVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR011990 (32.8%) IPR033985 (32.8%)" "RagB/SusD domain (34.5%) Tetratricopeptide-like helical domain superfamily (32.8%) SusD-like, N-terminal (32.8%)" LGLTFPELTAMQTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.9.1 (100%) pyruvate, phosphate dikinase (100%) "GO:0016301 (25.1%) GO:0046872 (25.1%) GO:0050242 (25.1%)" "kinase activity (25.1%) metal ion binding (25.1%) pyruvate, phosphate dikinase activity (25.1%)" "IPR000121 (10%) IPR008279 (10%) IPR010121 (10%)" "PEP-utilising enzyme, C-terminal (10%) PEP-utilising enzyme, mobile domain (10%) Pyruvate, phosphate dikinase (10%)" SLEGYYQETGR root "5.6.2.4 (88.8%) 3.6.4.12 (10.9%) 2.7.11.1 (0.1%)" "DNA 3'-5' helicase (88.8%) DNA helicase (10.9%) non-specific serine/threonine protein kinase (0.1%)" "GO:0006260 (8.4%) GO:0006281 (4.7%) GO:0006310 (4.7%)" "GO:0005737 (8.7%) GO:0030894 (4.7%) GO:0043590 (4.7%)" "GO:0043138 (8.7%) GO:0009378 (8.7%) GO:0005524 (8.6%)" "DNA replication (8.4%) DNA repair (4.7%) DNA recombination (4.7%)" "cytoplasm (8.7%) replisome (4.7%) bacterial nucleoid (4.7%)" "3'-5' DNA helicase activity (8.7%) four-way junction helicase activity (8.7%) ATP binding (8.6%)" "IPR001650 (8.2%) IPR027417 (8.2%) IPR032284 (8.2%)" "Helicase, C-terminal domain-like (8.2%) P-loop containing nucleoside triphosphate hydrolase (8.2%) ATP-dependent DNA helicase RecQ, zinc-binding domain (8.2%)" LVSMSEDELYEAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (23.7%) GO:0016843 (1.3%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (23.7%) amine-lyase activity (1.3%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" TPDAVESFAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "5.4.99.18 (88.2%) 4.1.1.21 (11.8%)" "5-(carboxyamino)imidazole ribonucleotide mutase (88.2%) phosphoribosylaminoimidazole carboxylase (11.8%)" GO:0006189 (34.2%) GO:0016020 (2.6%) "GO:0034023 (34.2%) GO:0016829 (28.9%)" 'de novo' IMP biosynthetic process (34.2%) membrane (2.6%) "5-(carboxyamino)imidazole ribonucleotide mutase activity (34.2%) lyase activity (28.9%)" "IPR000031 (33.3%) IPR024694 (33.3%) IPR033747 (33.3%)" "PurE domain (33.3%) PurE, prokaryotic type (33.3%) Class I PurE (33.3%)" LTSMVLALR Pseudomonadati Bacteria Pseudomonadati 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) "GO:0006428 (14.4%) GO:0006171 (0.2%) GO:0035556 (0.2%)" "GO:0005737 (14%) GO:0016020 (0.2%)" "GO:0000049 (14.4%) GO:0004822 (14.4%) GO:0005524 (14.4%)" "isoleucyl-tRNA aminoacylation (14.4%) cAMP biosynthetic process (0.2%) intracellular signal transduction (0.2%)" "cytoplasm (14%) membrane (0.2%)" "tRNA binding (14.4%) isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%)" "IPR013155 (12.6%) IPR023586 (12.6%) IPR033709 (12.6%)" "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.6%) Isoleucine-tRNA ligase, type 2 (12.6%) Isoleucyl tRNA synthetase type 2, anticodon-binding domain (12.6%)" LNDLGFLVTPYR Pseudomonadati Bacteria Pseudomonadati 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007645 (8.9%) IPR015712 (8.9%) IPR019462 (8.9%)" "RNA polymerase Rpb2, domain 3 (8.9%) DNA-directed RNA polymerase, subunit 2 (8.9%) DNA-directed RNA polymerase, beta subunit, external 1 domain (8.9%)" SVTNSLGGTFTLDYAHTTPTYGLPGGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (48.8%) GO:0005737 (48.8%)" GO:0016787 (2.3%) "extracellular region (48.8%) cytoplasm (48.8%)" hydrolase activity (2.3%) "IPR022045 (18.9%) IPR028994 (18.4%) IPR006530 (12.9%)" "Insecticide toxin TcdB middle/N-terminal (18.9%) Integrin alpha, N-terminal (18.4%) YD repeat (12.9%)" SGLQGLLDSYLGKAPEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006508 (24.1%) GO:0009636 (17.2%) GO:0043418 (17.2%)" GO:0005737 (17.2%) GO:0070005 (24.1%) "proteolysis (24.1%) response to toxic substance (17.2%) homocysteine catabolic process (17.2%)" cytoplasm (17.2%) cysteine-type aminopeptidase activity (24.1%) "IPR004134 (33.3%) IPR038765 (33.3%) IPR000169 (28.6%)" "Peptidase C1B, bleomycin hydrolase (33.3%) Papain-like cysteine peptidase superfamily (33.3%) Cysteine peptidase, cysteine active site (28.6%)" YFLEALDR root "1.12.1.3 (25%) 2.4.-.- (25%) 6.3.4.16 (25%)" "hydrogen dehydrogenase (NADP(+)) (25%) Glycosyltransferases (25%) carbamoyl-phosphate synthase (ammonia) (25%)" "GO:0000272 (8.1%) GO:0006526 (1.6%) GO:0006541 (1.6%)" "GO:0005829 (6.5%) GO:0005737 (1.6%) GO:0010008 (1.6%)" "GO:0016757 (46.8%) GO:0046872 (8.1%) GO:0052757 (8.1%)" "polysaccharide catabolic process (8.1%) L-arginine biosynthetic process (1.6%) glutamine metabolic process (1.6%)" "cytosol (6.5%) cytoplasm (1.6%) endosome membrane (1.6%)" "glycosyltransferase activity (46.8%) metal ion binding (8.1%) chondroitin hydrolase activity (8.1%)" "IPR028098 (32.6%) IPR036249 (14.6%) IPR008928 (5.6%)" "Glycosyltransferase subfamily 4-like, N-terminal domain (32.6%) Thioredoxin-like superfamily (14.6%) Six-hairpin glycosidase superfamily (5.6%)" QYDATGAPVYVNGKPVLNEESGYTEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.8%) IPR033985 (34.8%) IPR011990 (30.4%)" "RagB/SusD domain (34.8%) SusD-like, N-terminal (34.8%) Tetratricopeptide-like helical domain superfamily (30.4%)" GTPLLSELEFAGR Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.3.2.9 (100%) UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase (100%) "GO:0008360 (14.3%) GO:0009252 (14.3%) GO:0051301 (14.3%)" GO:0005737 (14.3%) "GO:0005524 (14.3%) GO:0008764 (14.3%) GO:0016874 (0.2%)" "regulation of cell shape (14.3%) peptidoglycan biosynthetic process (14.3%) cell division (14.3%)" cytoplasm (14.3%) "ATP binding (14.3%) UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (14.3%) ligase activity (0.2%)" "IPR005762 (20.1%) IPR013221 (20.1%) IPR004101 (20%)" "UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD (20.1%) Mur ligase, central (20.1%) Mur ligase, C-terminal (20%)" LLDLLPEVLNAGEDAGVLTEEGAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.7.1.- (100%) Phosphotransferases with an alcohol group as acceptor (100%) GO:0005975 (50%) GO:0016301 (50%) carbohydrate metabolic process (50%) kinase activity (50%) "IPR018484 (25.2%) IPR043129 (25.2%) IPR050406 (25.2%)" "Carbohydrate kinase FGGY, N-terminal (25.2%) ATPase, nucleotide binding domain (25.2%) FGGY Carbohydrate Kinase (25.2%)" AEAVYNYLASCGVTSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (87.5%) GO:0016020 (12.5%)" "cell outer membrane (87.5%) membrane (12.5%)" "IPR006665 (21.1%) IPR027367 (21.1%) IPR050330 (21.1%)" "OmpA-like domain (21.1%) YMGG-like Gly-zipper (21.1%) Bacterial Outer Membrane Structural/Functional (21.1%)" VLNDNFGLETGLMTTVHSTTATQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (21.9%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (21.9%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" YWNVMPEYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021958 (100%) Protein of unknown function DUF3575 (100%) TDNSAYPVNFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032339 (100%) Domain of unknown function DUF4859 (100%) AQEAVQEAVNLAQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0034605 (20%) GO:0042026 (20%)" GO:0005737 (20%) "GO:0005524 (20%) GO:0016887 (20%)" "cellular response to heat (20%) protein refolding (20%)" cytoplasm (20%) "ATP binding (20%) ATP hydrolysis activity (20%)" "IPR004176 (8.8%) IPR003593 (8.4%) IPR003959 (8.4%)" "Clp, repeat (R) N-terminal domain (8.8%) AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%)" FTLDDGSGVER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.10 (100%) methionine--tRNA ligase (100%) GO:0006431 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004825 (16.7%) GO:0005524 (16.7%)" methionyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) methionine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR001412 (8.3%) IPR002547 (8.3%) IPR004495 (8.3%)" "Aminoacyl-tRNA synthetase, class I, conserved site (8.3%) tRNA-binding domain (8.3%) Methionyl-tRNA synthetase, beta subunit, C-terminal (8.3%)" VLNLVNNNDFFGAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" VDFFGGDK Pseudomonadati Bacteria Pseudomonadati "3.2.1.22 (91.1%) 3.2.1.37 (4.4%) 3.2.1.- (2.2%)" "alpha-galactosidase (91.1%) xylan 1,4-beta-xylosidase (4.4%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.2%)" GO:0005975 (0.3%) GO:0016020 (0.3%) "GO:0030246 (50.2%) GO:0016798 (38.4%) GO:0016787 (6.5%)" carbohydrate metabolic process (0.3%) membrane (0.3%) "carbohydrate binding (50.2%) hydrolase activity, acting on glycosyl bonds (38.4%) hydrolase activity (6.5%)" "IPR019563 (12.8%) IPR052720 (12.8%) IPR013785 (12.7%)" "Glycosyl-hydrolase 97, catalytic domain (12.8%) Glycosyl Hydrolase Family 97 (12.8%) Aldolase-type TIM barrel (12.7%)" LYGLEAAVYQVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.20 (100%) tryptophan synthase (100%) GO:0005737 (25%) "GO:0004834 (25%) GO:0030170 (25%) GO:0052684 (25%)" cytoplasm (25%) "tryptophan synthase activity (25%) pyridoxal phosphate binding (25%) L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity (25%)" "IPR001926 (22.5%) IPR006316 (22.5%) IPR023026 (22.5%)" "Tryptophan synthase beta chain-like, PALP domain (22.5%) Tryptophan synthase, beta chain-like (22.5%) Tryptophan synthase beta chain/beta chain-like (22.5%)" VNQLGSLTETLDALEMAHR Pseudomonadati Bacteria Pseudomonadati 4.2.1.11 (100%) phosphopyruvate hydratase (100%) GO:0006096 (16.8%) "GO:0000015 (16.8%) GO:0005576 (16.5%) GO:0009986 (16.3%)" "GO:0000287 (16.8%) GO:0004634 (16.8%)" glycolytic process (16.8%) "phosphopyruvate hydratase complex (16.8%) extracellular region (16.5%) cell surface (16.3%)" "magnesium ion binding (16.8%) phosphopyruvate hydratase activity (16.8%)" "IPR000941 (16.7%) IPR020809 (16.7%) IPR020810 (16.7%)" "Enolase (16.7%) Enolase, conserved site (16.7%) Enolase, C-terminal TIM barrel domain (16.7%)" VLLEADMLDLK Bacteria Bacteria GO:0005737 (25%) "GO:0003743 (25%) GO:0005525 (25%) GO:0003924 (24.7%)" cytoplasm (25%) "translation initiation factor activity (25%) GTP binding (25%) GTPase activity (24.7%)" "IPR015760 (8.9%) IPR023115 (8.9%) IPR044145 (8.9%)" "Translation initiation factor IF- 2 (8.9%) Translation initiation factor IF- 2, domain 3 (8.9%) Translation initiation factor IF-2, domain II (8.9%)" LQATAMPLLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.8%) IPR001650 (7.8%) IPR004027 (7.8%)" "Protein translocase subunit SecA (7.8%) Helicase, C-terminal domain-like (7.8%) SEC-C motif (7.8%)" EFDCDKVPTTLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.25 (100%) 4-alpha-glucanotransferase (100%) GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.3%) IPR024742 (20.3%) IPR032790 (20.3%)" "Glycogen debranching enzyme (20.3%) Glycogen debranching enzyme, bacterial and archaeal type, N-terminal (20.3%) Glycogen debranching enzyme, C-terminal (20.3%)" QTNADLPLLFLTAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006355 (20%) "GO:0005829 (20%) GO:0032993 (20%)" "GO:0000156 (20%) GO:0000976 (20%)" regulation of DNA-templated transcription (20%) "cytosol (20%) protein-DNA complex (20%)" "phosphorelay response regulator activity (20%) transcription cis-regulatory region binding (20%)" "IPR001789 (23.1%) IPR039420 (23.1%) IPR001867 (19.2%)" "Signal transduction response regulator, receiver domain (23.1%) Transcriptional regulatory protein WalR-like (23.1%) OmpR/PhoB-type DNA-binding domain (19.2%)" LSLDEGKEFLGTYR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.1.19 (100%) arginine decarboxylase (100%) "GO:0006527 (19.8%) GO:0008295 (19.8%) GO:0033388 (19.8%)" "GO:0008792 (19.8%) GO:0046872 (19.8%) GO:0004497 (1.1%)" "L-arginine catabolic process (19.8%) spermidine biosynthetic process (19.8%) putrescine biosynthetic process from arginine (19.8%)" "arginine decarboxylase activity (19.8%) metal ion binding (19.8%) monooxygenase activity (1.1%)" "IPR002985 (11.3%) IPR022644 (11.3%) IPR022653 (11.3%)" "Arginine decarboxylase (11.3%) Orn/DAP/Arg decarboxylase 2, N-terminal (11.3%) Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site (11.3%)" FGLWLEPEMVNPK root "3.2.1.22 (99.8%) 3.2.1.- (0.2%)" "alpha-galactosidase (99.8%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (0.2%)" "GO:0016052 (49%) GO:0006031 (0.1%) GO:0006032 (0.1%)" "GO:0016020 (0.5%) GO:0005576 (0.1%) GO:0005886 (0.1%)" "GO:0004557 (49%) GO:0015098 (0.4%) GO:0016798 (0.2%)" "carbohydrate catabolic process (49%) chitin biosynthetic process (0.1%) chitin catabolic process (0.1%)" "membrane (0.5%) extracellular region (0.1%) plasma membrane (0.1%)" "alpha-galactosidase activity (49%) molybdate ion transmembrane transporter activity (0.4%) hydrolase activity, acting on glycosyl bonds (0.2%)" "IPR002252 (11.6%) IPR013785 (11.6%) IPR017853 (11.6%)" "Glycoside hydrolase family 36 (11.6%) Aldolase-type TIM barrel (11.6%) Glycoside hydrolase superfamily (11.6%)" EQLAWCTVTSPSAGVVGSLPFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0046677 (25%) "GO:0005886 (25%) GO:0030313 (25%)" GO:0022857 (25%) response to antibiotic (25%) "plasma membrane (25%) cell envelope (25%)" transmembrane transporter activity (25%) "IPR006143 (33.3%) IPR032317 (33.3%) IPR051160 (33.3%)" "RND efflux pump, membrane fusion protein (33.3%) Unknown (33.3%) Unknown (33.3%)" LKDCDDAPLLLFYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009294 (100%) DNA-mediated transformation (100%) "IPR003488 (50%) IPR057666 (50%)" "DNA recombination-mediator protein A (50%) Smf/DprA, SLOG domain (50%)" MTTDKEVQVADLFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.7%) GO:0009341 (25.7%) "GO:0004565 (25.7%) GO:0030246 (22.9%)" lactose catabolic process (25.7%) beta-galactosidase complex (25.7%) "beta-galactosidase activity (25.7%) carbohydrate binding (22.9%)" "IPR004199 (8.2%) IPR006102 (8.2%) IPR006103 (8.2%)" "Beta galactosidase small chain/ domain 5 (8.2%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (8.2%) Glycoside hydrolase family 2, catalytic domain (8.2%)" LYDEALNSGALPFAYSDDDVTTMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LEEMDMEDLRPLVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.2.7.1 (66.7%) 1.2.-.- (33.3%)" "pyruvate synthase (66.7%) Acting on the aldehyde or oxo group of donors (33.3%)" "GO:0006979 (14.7%) GO:0022900 (14.3%) GO:0044281 (13.6%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.7%) electron transport chain (14.3%) small molecule metabolic process (13.6%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.9%) IPR033412 (7.9%) IPR050722 (7.9%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.9%) Pyruvate:ferredoxin oxidoreductase, core domain II (7.9%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.9%)" ALVAAGPQL Bacteria Bacteria "4.1.1.49 (99%) 1.4.99.- (0.5%) 1.1.1.267 (0.3%)" "phosphoenolpyruvate carboxykinase (ATP) (99%) With other acceptors (0.5%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (0.3%)" "GO:0006094 (17%) GO:0055130 (0.6%) GO:0051484 (0.1%)" "GO:0005829 (17%) GO:0005737 (0.6%) GO:0005886 (0.6%)" "GO:0004612 (17%) GO:0005524 (17%) GO:0046872 (16.4%)" "gluconeogenesis (17%) D-alanine catabolic process (0.6%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process (0.1%)" "cytosol (17%) cytoplasm (0.6%) plasma membrane (0.6%)" "phosphoenolpyruvate carboxykinase (ATP) activity (17%) ATP binding (17%) metal ion binding (16.4%)" "IPR001272 (24.7%) IPR013035 (24.7%) IPR008210 (24.1%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (24.7%) Phosphoenolpyruvate carboxykinase, C-terminal (24.7%) Phosphoenolpyruvate carboxykinase, N-terminal (24.1%)" LKFDEEALDYLVDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0051301 (10.6%) GO:0051603 (10.6%)" GO:0009376 (10.6%) "GO:0005524 (10.6%) GO:0008233 (10.6%) GO:0016887 (10.6%)" "cell division (10.6%) proteolysis involved in protein catabolic process (10.6%)" HslUV protease complex (10.6%) "ATP binding (10.6%) peptidase activity (10.6%) ATP hydrolysis activity (10.6%)" "IPR019489 (12.3%) IPR027417 (12.3%) IPR050052 (12.3%)" "Clp ATPase, C-terminal (12.3%) P-loop containing nucleoside triphosphate hydrolase (12.3%) ATP-dependent Clp protease ATP-binding subunit ClpX (12.3%)" EADELFSQAEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.8%) GO:0022900 (14.1%) GO:0044281 (13.7%)" "GO:0030976 (14.5%) GO:0005506 (14.1%) GO:0051539 (14.1%)" "response to oxidative stress (14.8%) electron transport chain (14.1%) small molecule metabolic process (13.7%)" "thiamine pyrophosphate binding (14.5%) iron ion binding (14.1%) 4 iron, 4 sulfur cluster binding (14.1%)" "IPR029061 (8.1%) IPR050722 (8.1%) IPR011766 (7.9%)" "Thiamin diphosphate-binding fold (8.1%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8.1%) Thiamine pyrophosphate enzyme, TPP-binding (7.9%)" ALVNYTQTSEKSEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR024299 (25%) IPR035376 (25%) IPR038143 (25%)" "NigD-like N-terminal OB domain (25%) NigD-like, C-terminal domain (25%) NigD-like, C-terminal domain superfamily (25%)" EAYAALTPQAPAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.1.148 (100%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase (100%) "GO:0016114 (24.3%) GO:0019288 (24.3%)" "GO:0005524 (25.7%) GO:0050515 (25.7%)" "terpenoid biosynthetic process (24.3%) isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway (24.3%)" "ATP binding (25.7%) 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity (25.7%)" "IPR006204 (17.1%) IPR014721 (17.1%) IPR020568 (17.1%)" "GHMP kinase N-terminal domain (17.1%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (17.1%) Ribosomal protein uS5 domain 2-type superfamily (17.1%)" SSYGQNLLQHAR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.8%) "GO:0005886 (18.9%) GO:0016020 (1%)" "GO:0003723 (20.3%) GO:0016787 (19.9%) GO:0004521 (18.9%)" mRNA catabolic process (19.8%) "plasma membrane (18.9%) membrane (1%)" "RNA binding (20.3%) hydrolase activity (19.9%) RNA endonuclease activity (18.9%)" "IPR003607 (12.6%) IPR006674 (12.6%) IPR006675 (12.6%)" "HD/PDEase domain (12.6%) HD domain (12.6%) HDIG domain (12.6%)" ESYNSANYVTLYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) MTWSQVENLLLSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri VLKDLQELADNSQVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0008236 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type peptidase activity (33.3%) "IPR002142 (16.8%) IPR004634 (16.8%) IPR004635 (16.8%)" "Peptidase S49 (16.8%) Peptidase S49, protease IV (16.8%) Peptidase S49, SppA (16.8%)" EPYAPLFDNLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0045493 (25.2%) GO:0005576 (25.2%) "GO:0046559 (25.2%) GO:0033939 (24.5%)" xylan catabolic process (25.2%) extracellular region (25.2%) "alpha-glucuronidase activity (25.2%) xylan alpha-1,2-glucuronosidase activity (24.5%)" "IPR011099 (20.6%) IPR011100 (20.6%) IPR017853 (19.6%)" "Glycosyl hydrolase family 67, C-terminal (20.6%) Glycosyl hydrolase family 67, catalytic domain (20.6%) Glycoside hydrolase superfamily (19.6%)" AANVFTAGSWENK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.78 (100%) mannan endo-1,4-beta-mannosidase (100%) "GO:0006080 (25.7%) GO:0000272 (24.3%) GO:0030245 (5.7%)" "GO:0005576 (5.7%) GO:0009986 (5.7%)" "GO:0016985 (25.7%) GO:0008422 (5.7%) GO:0004553 (1.4%)" "substituted mannan metabolic process (25.7%) polysaccharide catabolic process (24.3%) cellulose catabolic process (5.7%)" "extracellular region (5.7%) cell surface (5.7%)" "mannan endo-1,4-beta-mannosidase activity (25.7%) beta-glucosidase activity (5.7%) hydrolase activity, hydrolyzing O-glycosyl compounds (1.4%)" "IPR022790 (26.4%) IPR001547 (24.1%) IPR017853 (24.1%)" "Glycosyl hydrolase family 26 domain (26.4%) Glycoside hydrolase, family 5 (24.1%) Glycoside hydrolase superfamily (24.1%)" NAWQEQANLNYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR036942 (26.1%) IPR041700 (26.1%) IPR037066 (25%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (26.1%) Outer membrane protein beta-barrel domain 3 (26.1%) TonB-dependent receptor, plug domain superfamily (25%)" LGLNQVTYAEELLKVEDGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009055 (100%) electron transfer activity (100%) "IPR000049 (20%) IPR012255 (20%) IPR014729 (20%)" "Electron transfer flavoprotein, beta-subunit, conserved site (20%) Electron transfer flavoprotein, beta subunit (20%) Rossmann-like alpha/beta/alpha sandwich fold (20%)" AVACGDDLYVFGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR046209 (59.3%) IPR015943 (40.7%)" "Domain of unknown function DUF6242, N-terminal domain (59.3%) WD40/YVTN repeat-like-containing domain superfamily (40.7%)" EGVNFVFK root "2.7.2.1 (86.8%) 1.1.1.100 (2.6%) 1.3.1.39 (2.6%)" "acetate kinase (86.8%) 3-oxoacyl-[acyl-carrier-protein] reductase (2.6%) enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific) (2.6%)" "GO:0006083 (15.5%) GO:0006085 (15.5%) GO:0006633 (0.5%)" "GO:0005737 (15.5%) GO:0005886 (1.5%)" "GO:0000287 (15.5%) GO:0005524 (15.5%) GO:0008776 (15.5%)" "acetate metabolic process (15.5%) acetyl-CoA biosynthetic process (15.5%) fatty acid biosynthetic process (0.5%)" "cytoplasm (15.5%) plasma membrane (1.5%)" "magnesium ion binding (15.5%) ATP binding (15.5%) acetate kinase activity (15.5%)" "IPR000890 (19.8%) IPR004372 (19.8%) IPR023865 (19.8%)" "Aliphatic acid kinase, short-chain (19.8%) Acetate/propionate kinase (19.8%) Aliphatic acid kinase, short-chain, conserved site (19.8%)" AFTGGSESDLGASLSTNSFTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" KLVPEGLAGR Pseudomonadati Bacteria Pseudomonadati 1.1.1.205 (100%) IMP dehydrogenase (100%) "GO:0006183 (20.1%) GO:0006177 (20%)" "GO:0003938 (20.1%) GO:0046872 (20%) GO:0000166 (19.7%)" "GTP biosynthetic process (20.1%) GMP biosynthetic process (20%)" "IMP dehydrogenase activity (20.1%) metal ion binding (20%) nucleotide binding (19.7%)" "IPR001093 (16.8%) IPR005990 (16.8%) IPR000644 (16.7%)" "IMP dehydrogenase/GMP reductase (16.8%) Inosine-5'-monophosphate dehydrogenase (16.8%) CBS domain (16.7%)" VLHQLLLDGVAGVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.17 (100%) 5-dehydro-4-deoxy-D-glucuronate isomerase (100%) "GO:0019698 (20%) GO:0042840 (20%) GO:0045490 (20%)" "GO:0008270 (20%) GO:0008697 (20%)" "D-galacturonate catabolic process (20%) D-glucuronate catabolic process (20%) pectin catabolic process (20%)" "zinc ion binding (20%) 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity (20%)" "IPR007045 (20.4%) IPR021120 (20.4%) IPR011051 (19.7%)" "5-keto 4-deoxyuronate isomerase (20.4%) KduI/IolB isomerase (20.4%) RmlC-like cupin domain superfamily (19.7%)" ESATAYTMEVAAPGLKK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (32.5%) IPR008978 (32.5%) IPR031107 (32.5%)" "Alpha crystallin/Hsp20 domain (32.5%) HSP20-like chaperone (32.5%) Small heat shock protein (32.5%)" HGALDPAVGQAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (20%) GO:0005829 (20%) "GO:0004180 (20%) GO:0004222 (20%) GO:0046872 (20%)" proteolysis (20%) cytosol (20%) "carboxypeptidase activity (20%) metalloendopeptidase activity (20%) metal ion binding (20%)" "IPR001567 (20.5%) IPR034005 (20.5%) IPR045090 (20.5%)" "Peptidase M3A/M3B catalytic domain (20.5%) Peptidyl-dipeptidase DCP (20.5%) Peptidase M3A/M3B (20.5%)" ATGALVSGPLPLPTHK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006412 (20%) "GO:0005840 (19.9%) GO:1990904 (19.9%) GO:0015935 (0.1%)" "GO:0003735 (20%) GO:0000049 (19.4%) GO:0003723 (0.7%)" translation (20%) "ribosome (19.9%) ribonucleoprotein complex (19.9%) small ribosomal subunit (0.1%)" "structural constituent of ribosome (20%) tRNA binding (19.4%) RNA binding (0.7%)" "IPR001848 (25%) IPR027486 (25%) IPR036838 (25%)" "Small ribosomal subunit protein uS10 (25%) Small ribosomal subunit protein uS10 domain (25%) Small ribosomal subunit protein uS10 domain superfamily (25%)" LTGDFGVFGSSFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR023997 (14.7%) IPR039426 (14.7%) IPR000531 (14.3%)" "TonB-dependent outer membrane protein SusC/RagA, conserved site (14.7%) TonB-dependent receptor-like (14.7%) TonB-dependent receptor-like, beta-barrel (14.3%)" DEFVNVLNQFGTDNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.1%) IPR012910 (12.1%) IPR023996 (12.1%)" "TonB-dependent receptor-like, beta-barrel (12.1%) TonB-dependent receptor, plug domain (12.1%) TonB-dependent outer membrane protein, SusC/RagA (12.1%)" VPYWTDSLKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.133 (100%) dTDP-4-dehydrorhamnose reductase (100%) GO:0019305 (33.3%) GO:0005829 (33.3%) GO:0008831 (33.3%) dTDP-rhamnose biosynthetic process (33.3%) cytosol (33.3%) dTDP-4-dehydrorhamnose reductase activity (33.3%) "IPR005913 (33.8%) IPR029903 (33.8%) IPR036291 (32.3%)" "dTDP-4-dehydrorhamnose reductase family (33.8%) RmlD-like substrate binding domain (33.8%) NAD(P)-binding domain superfamily (32.3%)" RLVSMSEDELYEAAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (23.7%) GO:0016843 (1.3%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (23.7%) amine-lyase activity (1.3%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" YFLAGTQANSSNLFADYYAAGK Pseudomonadati Bacteria Pseudomonadati "IPR012910 (34.5%) IPR023996 (34.5%) IPR037066 (31%)" "TonB-dependent receptor, plug domain (34.5%) TonB-dependent outer membrane protein, SusC/RagA (34.5%) TonB-dependent receptor, plug domain superfamily (31%)" TPASEEEWNELKR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005975 (43.5%) "GO:0004650 (43.5%) GO:0004557 (12.9%)" carbohydrate metabolic process (43.5%) "polygalacturonase activity (43.5%) alpha-galactosidase activity (12.9%)" "IPR000743 (20.6%) IPR006626 (20.6%) IPR051801 (20.6%)" "Glycoside hydrolase, family 28 (20.6%) Parallel beta-helix repeat (20.6%) Glycosyl_Hydrolase_28_Enzymes (20.6%)" LLTTHPSSSYALVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri DNLAVLESLPADVAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.1.90 (100%) diphosphate--fructose-6-phosphate 1-phosphotransferase (100%) "GO:0009749 (14.8%) GO:0006002 (13%)" GO:0005829 (14.8%) "GO:0003872 (14.8%) GO:0005524 (14.2%) GO:0046872 (14.2%)" "response to glucose (14.8%) fructose 6-phosphate metabolic process (13%)" cytosol (14.8%) "6-phosphofructokinase activity (14.8%) ATP binding (14.2%) metal ion binding (14.2%)" "IPR000023 (25.8%) IPR011183 (25.8%) IPR035966 (24.7%)" "Phosphofructokinase domain (25.8%) Pyrophosphate-dependent phosphofructokinase PfpB (25.8%) Phosphofructokinase superfamily (24.7%)" LKDTSWLHPVK Pseudomonadati Bacteria Pseudomonadati "GO:0030246 (51.4%) GO:0016787 (48.6%)" "carbohydrate binding (51.4%) hydrolase activity (48.6%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" VLLPDPVFNDQK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (20.2%) GO:0000028 (0.2%)" "GO:0015935 (20%) GO:0005840 (0.2%) GO:0022627 (0.2%)" "GO:0003735 (20.2%) GO:0019843 (20.2%) GO:0000049 (18.7%)" "translation (20.2%) ribosomal small subunit assembly (0.2%)" "small ribosomal subunit (20%) ribosome (0.2%) cytosolic small ribosomal subunit (0.2%)" "structural constituent of ribosome (20.2%) rRNA binding (20.2%) tRNA binding (18.7%)" "IPR000235 (25%) IPR005717 (25%) IPR023798 (25%)" "Small ribosomal subunit protein uS7 (25%) Small ribosomal subunit protein uS7, bacteria/organella (25%) Small ribosomal subunit protein uS7 domain (25%)" ADGLTGEVLLQNLECR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0006412 (19.6%) GO:0042274 (19.6%)" "GO:0015935 (19.6%) GO:0005840 (1.1%)" "GO:0019843 (20.7%) GO:0003735 (19.6%)" "translation (19.6%) ribosomal small subunit biogenesis (19.6%)" "small ribosomal subunit (19.6%) ribosome (1.1%)" "rRNA binding (20.7%) structural constituent of ribosome (19.6%)" "IPR001912 (17.3%) IPR036986 (17.3%) IPR002942 (16.4%)" "Small ribosomal subunit protein uS4, N-terminal (17.3%) RNA-binding S4 domain superfamily (17.3%) RNA-binding S4 domain (16.4%)" MPEFMDANEFMDYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" MHLPDDPAYYEK Bacteria Bacteria "3.5.1.77 (46.3%) 3.5.1.53 (43.8%) 4.1.3.- (8.8%)" "N-carbamoyl-D-amino-acid hydrolase (46.3%) N-carbamoylputrescine amidase (43.8%) Oxo-acid-lyases (8.8%)" GO:0033388 (42.5%) "GO:0050126 (42.5%) GO:0016746 (11.4%) GO:0047417 (2.9%)" putrescine biosynthetic process from arginine (42.5%) "N-carbamoylputrescine amidase activity (42.5%) acyltransferase activity (11.4%) N-carbamoyl-D-amino acid hydrolase activity (2.9%)" "IPR003010 (33.4%) IPR050345 (33.4%) IPR036526 (33.2%)" "Carbon-nitrogen hydrolase (33.4%) Aliphatic Amidase/Beta-Ureidopropionase (33.4%) Carbon-nitrogen hydrolase superfamily (33.2%)" ANLDLDVTK root GO:0043161 (6.7%) "GO:0009279 (80%) GO:0005634 (6.7%)" GO:0030674 (6.7%) proteasome-mediated ubiquitin-dependent protein catabolic process (6.7%) "cell outer membrane (80%) nucleus (6.7%)" protein-macromolecule adaptor activity (6.7%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" MKDLDWSNLSFGYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (12.6%) GO:0009098 (12.6%) GO:0009099 (12.6%)" "GO:0004084 (17.1%) GO:0052654 (7.2%) GO:0052655 (7.2%)" "isoleucine biosynthetic process (12.6%) L-leucine biosynthetic process (12.6%) L-valine biosynthetic process (12.6%)" "branched-chain-amino-acid transaminase activity (17.1%) L-leucine-2-oxoglutarate transaminase activity (7.2%) L-valine-2-oxoglutarate transaminase activity (7.2%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" LTFQHLTEEGLR Bacteroidota Bacteria Pseudomonadati Bacteroidota 1.1.1.23 (100%) histidinol dehydrogenase (100%) GO:0000105 (20%) GO:0005829 (20%) "GO:0004399 (20%) GO:0008270 (20%) GO:0051287 (20%)" L-histidine biosynthetic process (20%) cytosol (20%) "histidinol dehydrogenase activity (20%) zinc ion binding (20%) NAD binding (20%)" "IPR001692 (25.8%) IPR012131 (25.8%) IPR016161 (24.2%)" "Histidinol dehydrogenase, conserved site (25.8%) Histidinol dehydrogenase (25.8%) Aldehyde/histidinol dehydrogenase (24.2%)" NVLSLADLK root "3.1.3.48 (66.7%) 4.1.1.23 (33.3%)" "protein-tyrosine-phosphatase (66.7%) orotidine-5'-phosphate decarboxylase (33.3%)" "GO:0007165 (9.1%) GO:0009653 (9.1%) GO:0048666 (9.1%)" "GO:0005829 (9.1%) GO:0005886 (9.1%) GO:0030054 (9.1%)" "GO:0004497 (13.6%) GO:0050660 (13.6%) GO:0004725 (9.1%)" "signal transduction (9.1%) anatomical structure morphogenesis (9.1%) neuron development (9.1%)" "cytosol (9.1%) plasma membrane (9.1%) cell junction (9.1%)" "monooxygenase activity (13.6%) flavin adenine dinucleotide binding (13.6%) protein tyrosine phosphatase activity (9.1%)" "IPR043744 (70.4%) IPR036188 (4.2%) IPR050982 (4.2%)" "Domain of unknown function DUF5689 (70.4%) FAD/NAD(P)-binding domain superfamily (4.2%) Auxin biosynthesis and cation transport (4.2%)" SEQTDDTGVYLSELHTGDYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0004553 (33.3%) GO:0030246 (33.3%)" carbohydrate metabolic process (33.3%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.3%) carbohydrate binding (33.3%)" "IPR005084 (12.5%) IPR006584 (12.5%) IPR006710 (12.5%)" "Carbohydrate binding module family 6 (12.5%) Cellulose binding, type IV (12.5%) Glycoside hydrolase, family 43 (12.5%)" SFVVGSNSAALGGVYHLNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (50%) GO:0015483 (50%) cell outer membrane (50%) long-chain fatty acid transporting porin activity (50%) "IPR005017 (85.7%) IPR011250 (14.3%)" "Outer membrane protein transport protein (OMPP1/FadL/TodX) (85.7%) Outer membrane protein/outer membrane enzyme PagP, beta-barrel (14.3%)" LGFTLDWYNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR039426 (14.6%) IPR012910 (14.1%) IPR023996 (14.1%)" "TonB-dependent receptor-like (14.6%) TonB-dependent receptor, plug domain (14.1%) TonB-dependent outer membrane protein, SusC/RagA (14.1%)" NEVTYLDPSLTR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.8%) IPR012910 (12.8%) IPR023996 (12.8%)" "TonB-dependent receptor-like, beta-barrel (12.8%) TonB-dependent receptor, plug domain (12.8%) TonB-dependent outer membrane protein, SusC/RagA (12.8%)" GVEAFVPVWNVENCLQCNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.7.1 (100%) pyruvate synthase (100%) "GO:0006979 (14.3%) GO:0022900 (14.3%) GO:0044281 (14%)" "GO:0005506 (14.3%) GO:0030976 (14.3%) GO:0051539 (14.3%)" "response to oxidative stress (14.3%) electron transport chain (14.3%) small molecule metabolic process (14%)" "iron ion binding (14.3%) thiamine pyrophosphate binding (14.3%) 4 iron, 4 sulfur cluster binding (14.3%)" "IPR002880 (7.8%) IPR011766 (7.8%) IPR011895 (7.8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (7.8%) Thiamine pyrophosphate enzyme, TPP-binding (7.8%) Pyruvate-flavodoxin oxidoreductase (7.8%)" AYDTDLYTRPELER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.85 (100%) 3-isopropylmalate dehydrogenase (100%) GO:0009098 (20%) GO:0005829 (20%) "GO:0000287 (20%) GO:0003862 (20%) GO:0051287 (20%)" L-leucine biosynthetic process (20%) cytosol (20%) "magnesium ion binding (20%) 3-isopropylmalate dehydrogenase activity (20%) NAD binding (20%)" "IPR004429 (33.3%) IPR019818 (33.3%) IPR024084 (33.3%)" "Isopropylmalate dehydrogenase (33.3%) Isocitrate/isopropylmalate dehydrogenase, conserved site (33.3%) Isopropylmalate dehydrogenase-like domain (33.3%)" YLNVEDTSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 4.1.1.65 (100%) phosphatidylserine decarboxylase (100%) GO:0006646 (33.3%) GO:0005886 (33.3%) GO:0004609 (33.3%) phosphatidylethanolamine biosynthetic process (33.3%) plasma membrane (33.3%) phosphatidylserine decarboxylase activity (33.3%) "IPR003817 (50%) IPR033175 (50%)" "Phosphatidylserine decarboxylase-related (50%) Phosphatidylserine decarboxylase, prokaryotes (50%)" GADVSWLTEMEKDGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (44%) "GO:0015926 (44%) GO:0031218 (12%)" pectin catabolic process (44%) "glucosidase activity (44%) arabinogalactan endo-1,4-beta-galactosidase activity (12%)" "IPR011683 (52.4%) IPR017853 (47.6%)" "Glycosyl hydrolase family 53 (52.4%) Glycoside hydrolase superfamily (47.6%)" FYGLGADGTVGANK root "1.2.7.- (51.6%) 1.2.7.1 (45.5%) 1.2.1.51 (1.6%)" "With an iron-sulfur protein as acceptor (51.6%) pyruvate synthase (45.5%) pyruvate dehydrogenase (NADP(+)) (1.6%)" "GO:0006979 (15.1%) GO:0022900 (14.9%) GO:0044281 (10.2%)" "GO:0051539 (15%) GO:0005506 (14.9%) GO:0030976 (14.5%)" "response to oxidative stress (15.1%) electron transport chain (14.9%) small molecule metabolic process (10.2%)" "4 iron, 4 sulfur cluster binding (15%) iron ion binding (14.9%) thiamine pyrophosphate binding (14.5%)" "IPR050722 (7.8%) IPR019752 (7.8%) IPR002869 (7.8%)" "Pyruvate:ferredoxin/flavodoxin oxidoreductase (7.8%) Pyruvate/ketoisovalerate oxidoreductase, catalytic domain (7.8%) Pyruvate-flavodoxin oxidoreductase, central domain (7.8%)" FEEVMAAFGDRPLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0055085 (50%) GO:0016020 (50%) transmembrane transport (50%) membrane (50%) "IPR001902 (25.3%) IPR002645 (25.3%) IPR036513 (25.3%)" "SLC26A/SulP transporter (25.3%) STAS domain (25.3%) STAS domain superfamily (25.3%)" LMGNFYLR root "GO:0009279 (96.6%) GO:0016020 (3.4%)" "cell outer membrane (96.6%) membrane (3.4%)" "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LMEAEAALK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0055085 (50%) GO:0016020 (50%) transmembrane transport (50%) membrane (50%) "IPR043602 (36.8%) IPR050739 (36.8%) IPR032317 (26.3%)" "Unknown (36.8%) Membrane Fusion Protein (36.8%) Unknown (26.3%)" VNDFAALLALK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005737 (48.7%) GO:0003746 (51.3%) cytoplasm (48.7%) translation elongation factor activity (51.3%) "IPR001816 (20%) IPR009060 (20%) IPR014039 (20%)" "Translation elongation factor EFTs/EF1B (20%) UBA-like superfamily (20%) Translation elongation factor EFTs/EF1B, dimerisation (20%)" TAGSNYVVHLVANNQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR004564 (50%) IPR029046 (50%)" "Outer membrane lipoprotein carrier protein LolA-like (50%) Lipoprotein localisation LolA/LolB/LppX (50%)" ANVLVVPNLEVGNLGYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.1.8 (100%) phosphate acetyltransferase (100%) "GO:0016407 (60.8%) GO:0008959 (39.2%)" "acetyltransferase activity (60.8%) phosphate acetyltransferase activity (39.2%)" "IPR002505 (17%) IPR050500 (17%) IPR004614 (16.8%)" "Phosphate acetyl/butaryl transferase (17%) Phosphate Acetyltransferase/Butyryltransferase (17%) Phosphate acetyltransferase (16.8%)" ALQDYVLNDLSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0034605 (20.1%) GO:0042026 (19.4%)" GO:0005737 (20.1%) "GO:0005524 (20.1%) GO:0016887 (20.1%)" "cellular response to heat (20.1%) protein refolding (19.4%)" cytoplasm (20.1%) "ATP binding (20.1%) ATP hydrolysis activity (20.1%)" "IPR003593 (8.4%) IPR003959 (8.4%) IPR018368 (8.4%)" "AAA+ ATPase domain (8.4%) ATPase, AAA-type, core (8.4%) ClpA/B, conserved site 1 (8.4%)" LKMEHALYVQQLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001911 (50%) IPR038380 (50%)" "Small ribosomal subunit protein bS21 (50%) Small ribosomal subunit protein bS21 superfamily (50%)" VPFLNFFDGFR root "1.2.7.1 (85.7%) 1.2.7.- (12.4%) 1.2.-.- (1%)" "pyruvate synthase (85.7%) With an iron-sulfur protein as acceptor (12.4%) Acting on the aldehyde or oxo group of donors (1%)" "GO:0006979 (16.4%) GO:0022900 (15.8%) GO:0044281 (3.1%)" "GO:0051539 (16.2%) GO:0005506 (15.8%) GO:0030976 (14.9%)" "response to oxidative stress (16.4%) electron transport chain (15.8%) small molecule metabolic process (3.1%)" "4 iron, 4 sulfur cluster binding (16.2%) iron ion binding (15.8%) thiamine pyrophosphate binding (14.9%)" "IPR002880 (8%) IPR050722 (8%) IPR029061 (8%)" "Pyruvate flavodoxin/ferredoxin oxidoreductase, pyrimidine binding domain (8%) Pyruvate:ferredoxin/flavodoxin oxidoreductase (8%) Thiamin diphosphate-binding fold (8%)" AYELLPESPEGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LDLPELPELMLDNTDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.1.2 (100%) glutamine synthetase (100%) GO:0006542 (49.6%) GO:0004356 (50.4%) glutamine biosynthetic process (49.6%) glutamine synthetase activity (50.4%) "IPR008146 (14.5%) IPR027303 (14.5%) IPR040577 (14.5%)" "Glutamine synthetase, catalytic domain (14.5%) Glutamine synthetase, glycine-rich site (14.5%) Glutamine synthetase, C-terminal (14.5%)" LTNLLLSELLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.1.2.4 (100%) deoxyribose-phosphate aldolase (100%) "GO:0009264 (25%) GO:0016052 (25%)" GO:0005737 (25%) GO:0004139 (25%) "deoxyribonucleotide catabolic process (25%) carbohydrate catabolic process (25%)" cytoplasm (25%) deoxyribose-phosphate aldolase activity (25%) "IPR002915 (33.3%) IPR011343 (33.3%) IPR013785 (33.3%)" "DeoC/FbaB/LacD aldolase (33.3%) Deoxyribose-phosphate aldolase (33.3%) Aldolase-type TIM barrel (33.3%)" YVDLLVNDGVKDTFLQR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0000287 (16.7%) GO:0004824 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) magnesium ion binding (16.7%) lysine-tRNA ligase activity (16.7%)" "IPR002313 (12.5%) IPR004364 (12.5%) IPR004365 (12.5%)" "Lysine-tRNA ligase, class II (12.5%) Aminoacyl-tRNA synthetase, class II (D/K/N) (12.5%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.5%)" VYGGENAPYLWVK Bacteria Bacteria 2.6.1.83 (100%) LL-diaminopimelate aminotransferase (100%) "GO:0033362 (30.1%) GO:0009089 (1.5%)" "GO:0030170 (33.8%) GO:0010285 (32.3%) GO:0008483 (2.3%)" "lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway (30.1%) lysine biosynthetic process via diaminopimelate (1.5%)" "pyridoxal phosphate binding (33.8%) L,L-diaminopimelate aminotransferase activity (32.3%) transaminase activity (2.3%)" "IPR019942 (21.3%) IPR004839 (20.8%) IPR015422 (19.9%)" "LL-diaminopimelate aminotransferase/aminotransferase ALD1 (21.3%) Aminotransferase, class I/classII, large domain (20.8%) Pyridoxal phosphate-dependent transferase, small domain (19.9%)" ENGTWALAEGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006826 (46.7%) GO:0009279 (53.3%) iron ion transport (46.7%) cell outer membrane (53.3%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" VGEYEATVHYHK Pseudomonadati Bacteria Pseudomonadati GO:0006412 (19.7%) "GO:0005840 (21.2%) GO:1990904 (19.7%)" "GO:0003735 (19.7%) GO:0019843 (19.7%)" translation (19.7%) "ribosome (21.2%) ribonucleoprotein complex (19.7%)" "structural constituent of ribosome (19.7%) rRNA binding (19.7%)" "IPR020069 (15.1%) IPR036791 (15.1%) IPR000244 (14%)" "Large ribosomal subunit protein bL9, C-terminal (15.1%) Large ribosomal subunit protein bL9, C-terminal domain superfamily (15.1%) Large ribosomal subunit protein bL9 (14%)" SNDLSGNLEVDYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" DKVDYYNLTVDDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (15.9%) GO:0043335 (15.9%) GO:0051083 (15.9%)" GO:0005737 (4.8%) "GO:0003755 (15.9%) GO:0043022 (15.9%) GO:0044183 (15.9%)" "protein transport (15.9%) protein unfolding (15.9%) 'de novo' cotranslational protein folding (15.9%)" cytoplasm (4.8%) "peptidyl-prolyl cis-trans isomerase activity (15.9%) ribosome binding (15.9%) protein folding chaperone (15.9%)" "IPR005215 (19.4%) IPR008881 (19.4%) IPR027304 (18.4%)" "Trigger factor (19.4%) Trigger factor, ribosome-binding, bacterial (19.4%) Trigger factor/SurA domain superfamily (18.4%)" ADANGNQADMFVCGVNTDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.2.1.- (100%) With NAD(+) or NADP(+) as acceptor (100%) GO:0006006 (25%) "GO:0050661 (25%) GO:0051287 (25%) GO:0016620 (18.8%)" glucose metabolic process (25%) "NADP binding (25%) NAD binding (25%) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (18.8%)" "IPR006424 (16.7%) IPR020828 (16.7%) IPR020829 (16.7%)" "Glyceraldehyde-3-phosphate dehydrogenase, type I (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (16.7%) Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (16.7%)" LQLGGNDQWGNMTTGTELLHR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.1 (100%) tyrosine--tRNA ligase (100%) GO:0006437 (16.8%) GO:0005829 (16.8%) "GO:0003723 (16.8%) GO:0004831 (16.8%) GO:0005524 (16.8%)" tyrosyl-tRNA aminoacylation (16.8%) cytosol (16.8%) "RNA binding (16.8%) tyrosine-tRNA ligase activity (16.8%) ATP binding (16.8%)" "IPR002305 (12.8%) IPR002307 (12.8%) IPR024088 (12.8%)" "Aminoacyl-tRNA synthetase, class Ic (12.8%) Tyrosine-tRNA ligase (12.8%) Tyrosine-tRNA ligase, bacterial-type (12.8%)" GGLGGLSDGGLTVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR021255 (100%) Putative auto-transporter adhesin, head GIN domain (100%) LTYALDEVGYSLAQTYEANHAEEA Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0017038 (50%) GO:0005886 (50%) protein import (50%) plasma membrane (50%) "IPR002898 (50%) IPR050790 (50%)" "MotA/TolQ/ExbB proton channel (50%) ExbB/TolQ Biopolymer Transport (50%)" GSNGQPFPYFYGYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR023996 (13%) IPR039426 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent outer membrane protein, SusC/RagA (13%) TonB-dependent receptor-like (13%)" GLFTWEGYPYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009446 (33.3%) "GO:0004668 (33.3%) GO:0047632 (33.3%)" putrescine biosynthetic process (33.3%) "protein-arginine deiminase activity (33.3%) agmatine deiminase activity (33.3%)" IPR007466 (100%) Peptidyl-arginine deiminase, Porphyromonas-type (100%) ELDKPFLMPLEDVFSLTGR Bacteria Bacteria 3.6.5.3 (100%) protein-synthesizing GTPase (100%) "GO:0005829 (14%) GO:0032045 (11.8%)" "GO:0003746 (16.3%) GO:0003924 (16.3%) GO:0005525 (16.3%)" "cytosol (14%) guanyl-nucleotide exchange factor complex (11.8%)" "translation elongation factor activity (16.3%) GTPase activity (16.3%) GTP binding (16.3%)" "IPR000795 (8.4%) IPR004160 (8.4%) IPR004161 (8.4%)" "Translational (tr)-type GTP-binding domain (8.4%) Translation elongation factor EFTu/EF1A, C-terminal (8.4%) Translation elongation factor EFTu-like, domain 2 (8.4%)" GYACEFYLDAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.6.1.42 (100%) branched-chain-amino-acid transaminase (100%) "GO:0009097 (16.6%) GO:0009098 (16.6%) GO:0009099 (16.6%)" "GO:0004084 (17.9%) GO:0052654 (5.9%) GO:0052655 (5.9%)" "isoleucine biosynthetic process (16.6%) L-leucine biosynthetic process (16.6%) L-valine biosynthetic process (16.6%)" "branched-chain-amino-acid transaminase activity (17.9%) L-leucine-2-oxoglutarate transaminase activity (5.9%) L-valine-2-oxoglutarate transaminase activity (5.9%)" "IPR001544 (16.7%) IPR005786 (16.7%) IPR033939 (16.7%)" "Aminotransferase class IV (16.7%) Branched-chain amino acid aminotransferase II (16.7%) Branched-chain aminotransferase (16.7%)" NAVNGLAYVLTESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" LGVDMVDEHYYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17%) IPR010720 (17%) IPR051563 (17%)" "Carbohydrate-binding, CenC-like (17%) Alpha-L-arabinofuranosidase, C-terminal (17%) Glycosyl Hydrolase Family 51 (17%)" WTKDEHTNGLLQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (20%) GO:0000428 (20%) "GO:0003677 (20%) GO:0003899 (20%) GO:0032549 (20%)" DNA-templated transcription (20%) DNA-directed RNA polymerase complex (20%) "DNA binding (20%) DNA-directed RNA polymerase activity (20%) ribonucleoside binding (20%)" "IPR007120 (7.9%) IPR007121 (7.9%) IPR007641 (7.9%)" "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain (7.9%) RNA polymerase, beta subunit, conserved site (7.9%) RNA polymerase Rpb2, domain 7 (7.9%)" LFPAVNLLSSSTR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.6.4.- (100%) Acting on ATP; involved in cellular and subcellular movement (100%) GO:0006353 (14.4%) GO:0005829 (13.9%) "GO:0003723 (14.4%) GO:0004386 (14.4%) GO:0005524 (14.4%)" DNA-templated transcription termination (14.4%) cytosol (13.9%) "RNA binding (14.4%) helicase activity (14.4%) ATP binding (14.4%)" "IPR000194 (10.7%) IPR003593 (10.7%) IPR004665 (10.7%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.7%) AAA+ ATPase domain (10.7%) Transcription termination factor Rho (10.7%)" FTNAMYVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0006826 (46.9%) GO:0006811 (3.1%)" GO:0009279 (50%) "iron ion transport (46.9%) monoatomic ion transport (3.1%)" cell outer membrane (50%) "IPR000531 (25.4%) IPR012910 (25.4%) IPR039426 (25.4%)" "TonB-dependent receptor-like, beta-barrel (25.4%) TonB-dependent receptor, plug domain (25.4%) TonB-dependent receptor-like (25.4%)" TDLASTYTFLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SLLTGDYLFVSK Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.4.21.89 (100%) signal peptidase I (100%) GO:0006465 (33.3%) GO:0016020 (33.3%) GO:0004252 (33.3%) signal peptide processing (33.3%) membrane (33.3%) serine-type endopeptidase activity (33.3%) "IPR019533 (25.2%) IPR000223 (25.1%) IPR019758 (25.1%)" "Peptidase S26 (25.2%) Peptidase S26A, signal peptidase I (25.1%) Peptidase S26A, signal peptidase I, conserved site (25.1%)" QSLLQALAEQSR root "2.7.7.6 (71.4%) 1.2.1.11 (14.3%) 2.7.7.8 (14.3%)" "DNA-directed RNA polymerase (71.4%) aspartate-semialdehyde dehydrogenase (14.3%) polyribonucleotide nucleotidyltransferase (14.3%)" "GO:0006352 (33.3%) GO:0005975 (0%) GO:0006355 (0%)" "GO:0000428 (0.1%) GO:0005829 (0%) GO:1903865 (0%)" "GO:0016987 (33.2%) GO:0003677 (32.9%) GO:0003700 (0.1%)" "DNA-templated transcription initiation (33.3%) carbohydrate metabolic process (0%) regulation of DNA-templated transcription (0%)" "DNA-directed RNA polymerase complex (0.1%) cytosol (0%) sigma factor antagonist complex (0%)" "sigma factor activity (33.2%) DNA binding (32.9%) DNA-binding transcription factor activity (0.1%)" "IPR050239 (10%) IPR014284 (10%) IPR007624 (10%)" "Sigma-70 factor family, RNA polymerase initiation factors (10%) RNA polymerase sigma-70-like domain (10%) RNA polymerase sigma-70 region 3 (10%)" FLTDLKPDADADFAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.290 (66.7%) 1.1.1.95 (33.3%)" "4-phosphoerythronate dehydrogenase (66.7%) phosphoglycerate dehydrogenase (33.3%)" "GO:0051287 (50%) GO:0016616 (44.4%) GO:0033711 (3.7%)" "NAD binding (50%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (44.4%) 4-phosphoerythronate dehydrogenase activity (3.7%)" "IPR006139 (29.7%) IPR006140 (29.7%) IPR036291 (29.7%)" "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (29.7%) D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain (29.7%) NAD(P)-binding domain superfamily (29.7%)" LDYSYLHVGGR Bacteria Bacteria GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR000531 (16.9%) IPR012910 (16.9%) IPR039426 (16.9%)" "TonB-dependent receptor-like, beta-barrel (16.9%) TonB-dependent receptor, plug domain (16.9%) TonB-dependent receptor-like (16.9%)" APQCFYLEER Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 1.1.1.40 (100%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (100%) GO:0006108 (16.3%) "GO:0016746 (16.9%) GO:0046872 (16.9%) GO:0051287 (16.9%)" malate metabolic process (16.3%) "acyltransferase activity (16.9%) metal ion binding (16.9%) NAD binding (16.9%)" "IPR002505 (9.3%) IPR012301 (9.3%) IPR012302 (9.3%)" "Phosphate acetyl/butaryl transferase (9.3%) Malic enzyme, N-terminal domain (9.3%) Malic enzyme, NAD-binding (9.3%)" KSVLTGVEMFR root 3.6.5.3 (100%) protein-synthesizing GTPase (100%) GO:0070125 (0.2%) "GO:0005829 (15%) GO:0032045 (12.3%) GO:0005739 (0.2%)" "GO:0003746 (15.3%) GO:0005525 (15.3%) GO:0003924 (14.4%)" mitochondrial translational elongation (0.2%) "cytosol (15%) guanyl-nucleotide exchange factor complex (12.3%) mitochondrion (0.2%)" "translation elongation factor activity (15.3%) GTP binding (15.3%) GTPase activity (14.4%)" "IPR004161 (8.7%) IPR009000 (8.7%) IPR033720 (8.7%)" "Translation elongation factor EFTu-like, domain 2 (8.7%) Translation protein, beta-barrel domain superfamily (8.7%) Elongation factor Tu, domain 2 (8.7%)" LPGAEVSDDGTLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (66.7%) GO:0030246 (33.3%) cell outer membrane (66.7%) carbohydrate binding (33.3%) "IPR041700 (72.2%) IPR008969 (24.1%) IPR036942 (2.5%)" "Outer membrane protein beta-barrel domain 3 (72.2%) Carboxypeptidase-like, regulatory domain superfamily (24.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (2.5%)" VLQLLSR root "2.6.1.9 (38.5%) 2.7.11.1 (5.9%) 2.3.2.27 (4.2%)" "histidinol-phosphate transaminase (38.5%) non-specific serine/threonine protein kinase (5.9%) RING-type E3 ubiquitin transferase (4.2%)" "GO:0034605 (14.4%) GO:0042026 (7.8%) GO:0006508 (5.2%)" "GO:0005737 (14.9%) GO:0016020 (1.2%) GO:0005886 (0.6%)" "GO:0005524 (15.2%) GO:0016887 (14.7%) GO:0008233 (5.1%)" "cellular response to heat (14.4%) protein refolding (7.8%) proteolysis (5.2%)" "cytoplasm (14.9%) membrane (1.2%) plasma membrane (0.6%)" "ATP binding (15.2%) ATP hydrolysis activity (14.7%) peptidase activity (5.1%)" "IPR027417 (7.4%) IPR003593 (7.3%) IPR003959 (7.2%)" "P-loop containing nucleoside triphosphate hydrolase (7.4%) AAA+ ATPase domain (7.3%) ATPase, AAA-type, core (7.2%)" QLSLADMFAETLR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.2%) GO:0006164 (11.2%) GO:0009156 (10.7%)" "GO:0002189 (11.2%) GO:0005737 (11.2%)" "GO:0000287 (11.2%) GO:0004749 (11.2%) GO:0016301 (11.2%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.2%) purine nucleotide biosynthetic process (11.2%) ribonucleoside monophosphate biosynthetic process (10.7%)" "ribose phosphate diphosphokinase complex (11.2%) cytoplasm (11.2%)" "magnesium ion binding (11.2%) ribose phosphate diphosphokinase activity (11.2%) kinase activity (11.2%)" "IPR000836 (18.8%) IPR005946 (18.8%) IPR029057 (18.8%)" "Phosphoribosyltransferase domain (18.8%) Ribose-phosphate pyrophosphokinase (18.8%) Phosphoribosyltransferase-like (18.8%)" WVADECDALLQSGALPFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" SLVVVVNKWDLVEEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.6.5.- (100%) Acting on GTP; involved in cellular and subcellular movement (100%) GO:0042254 (30.9%) "GO:0005525 (30.9%) GO:0043022 (30.9%) GO:0016787 (7.2%)" ribosome biogenesis (30.9%) "GTP binding (30.9%) ribosome binding (30.9%) hydrolase activity (7.2%)" "IPR005225 (14.4%) IPR006073 (14.4%) IPR016484 (14.4%)" "Small GTP-binding domain (14.4%) GTP binding domain (14.4%) GTPase Der (14.4%)" TDEEGFALLK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (16.8%) "GO:0005840 (16.8%) GO:1990904 (16.8%)" "GO:0003735 (16.8%) GO:0000049 (16.5%) GO:0019843 (16.5%)" translation (16.8%) "ribosome (16.8%) ribonucleoprotein complex (16.8%)" "structural constituent of ribosome (16.8%) tRNA binding (16.5%) rRNA binding (16.5%)" "IPR002132 (19.9%) IPR020930 (19.9%) IPR022803 (19.9%)" "Large ribosomal subunit protein uL5 (19.9%) Large ribosomal subunit protein uL5, bacteria (19.9%) Large ribosomal subunit protein uL5 domain superfamily (19.9%)" LFEEAELAK root "GO:0006171 (14.3%) GO:0006366 (14.3%) GO:0035556 (14.3%)" "GO:0005634 (14.3%) GO:0016020 (14.3%)" "GO:0003713 (14.3%) GO:0004016 (14.3%)" "cAMP biosynthetic process (14.3%) transcription by RNA polymerase II (14.3%) intracellular signal transduction (14.3%)" "nucleus (14.3%) membrane (14.3%)" "transcription coactivator activity (14.3%) adenylate cyclase activity (14.3%)" "IPR010106 (95.9%) IPR001054 (0.6%) IPR007890 (0.6%)" "Recombination-promoting nuclease RpnA (95.9%) Adenylyl cyclase class-3/4/guanylyl cyclase (0.6%) CHASE2 (0.6%)" LGMDLANLLWDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 7.4.2.8 (100%) protein-secreting ATPase (100%) "GO:0006605 (11.1%) GO:0017038 (11.1%) GO:0043952 (11.1%)" "GO:0005829 (11.1%) GO:0005886 (11.1%) GO:0031522 (11.1%)" "GO:0005524 (11.1%) GO:0046872 (11.1%)" "protein targeting (11.1%) protein import (11.1%) protein transport by the Sec complex (11.1%)" "cytosol (11.1%) plasma membrane (11.1%) cell envelope Sec protein transport complex (11.1%)" "ATP binding (11.1%) metal ion binding (11.1%)" "IPR000185 (7.7%) IPR001650 (7.7%) IPR004027 (7.7%)" "Protein translocase subunit SecA (7.7%) Helicase, C-terminal domain-like (7.7%) SEC-C motif (7.7%)" FQGGPNAGHTLEFEGEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.3.4.4 (100%) adenylosuccinate synthase (100%) "GO:0044208 (16.7%) GO:0046040 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004019 (16.7%) GO:0005525 (16.7%)" "'de novo' AMP biosynthetic process (16.7%) IMP metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) adenylosuccinate synthase activity (16.7%) GTP binding (16.7%)" "IPR001114 (14.3%) IPR018220 (14.3%) IPR027417 (14.3%)" "Adenylosuccinate synthetase (14.3%) Adenylosuccinate synthase, GTP-binding site (14.3%) P-loop containing nucleoside triphosphate hydrolase (14.3%)" TLHPDNMAAGPASYGMTDTMGR root IPR025964 (100%) GGGtGRT protein (100%) VGLLQLHNTADLANNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0033388 (40.9%) "GO:0050126 (40.9%) GO:0016746 (18.2%)" putrescine biosynthetic process from arginine (40.9%) "N-carbamoylputrescine amidase activity (40.9%) acyltransferase activity (18.2%)" "IPR003010 (33.8%) IPR050345 (33.8%) IPR036526 (32.5%)" "Carbon-nitrogen hydrolase (33.8%) Aliphatic Amidase/Beta-Ureidopropionase (33.8%) Carbon-nitrogen hydrolase superfamily (32.5%)" GMGLEQVVELLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "2.1.1.192 (91.7%) 2.1.1.- (8.3%)" "23S rRNA (adenine(2503)-C(2))-methyltransferase (91.7%) Methyltransferases (8.3%)" "GO:0030488 (13.4%) GO:0070475 (13.4%)" GO:0005737 (12.7%) "GO:0046872 (13.4%) GO:0051539 (13.4%) GO:0000049 (6.7%)" "tRNA methylation (13.4%) rRNA base methylation (13.4%)" cytoplasm (12.7%) "metal ion binding (13.4%) 4 iron, 4 sulfur cluster binding (13.4%) tRNA binding (6.7%)" "IPR007197 (17.5%) IPR040072 (17.5%) IPR013785 (16.5%)" "Radical SAM (17.5%) Methyltransferase (Class A) (17.5%) Aldolase-type TIM barrel (16.5%)" TGFSQNYDLSVSHANDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" FCLSTFACNTCQEVNGVSK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.4.1.1 (100%) glycogen phosphorylase (100%) GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" QLYAVYPFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (33.3%) "GO:0008184 (33.3%) GO:0030170 (33.3%)" carbohydrate metabolic process (33.3%) "glycogen phosphorylase activity (33.3%) pyridoxal phosphate binding (33.3%)" "IPR000811 (25%) IPR011834 (25%) IPR024517 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen phosphorylase, domain of unknown function DUF3417 (25%)" MPLDLQLGVTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri AHSLAAQGGLNAAK root "1.3.5.1 (98.5%) 1.3.5.4 (1.4%) 1.3.99.1 (0.1%)" "succinate dehydrogenase (98.5%) Transferred entry: 1.3.5.1 (1.4%) Deleted entry (0.1%)" "GO:0009061 (18.7%) GO:0006108 (0%) GO:0006633 (0%)" "GO:0005886 (18.7%) GO:0005829 (0%) GO:0009317 (0%)" "GO:0009055 (18.7%) GO:0050660 (18.7%) GO:0000104 (14.5%)" "anaerobic respiration (18.7%) malate metabolic process (0%) fatty acid biosynthetic process (0%)" "plasma membrane (18.7%) cytosol (0%) acetyl-CoA carboxylase complex (0%)" "electron transfer activity (18.7%) flavin adenine dinucleotide binding (18.7%) succinate dehydrogenase activity (14.5%)" "IPR003953 (14.4%) IPR030664 (14.4%) IPR036188 (14.4%)" "FAD-dependent oxidoreductase 2, FAD-binding domain (14.4%) FAD-dependent oxidoreductase SdhA/FrdA/AprA (14.4%) FAD/NAD(P)-binding domain superfamily (14.4%)" LAAEFGDNLKK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "1.1.1.37 (50%) 1.1.1.40 (50%)" "malate dehydrogenase (50%) malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (50%)" "GO:0006108 (33.3%) GO:0006089 (1.2%)" GO:0016020 (1.2%) "GO:0016615 (29.8%) GO:0016616 (29.8%) GO:0004473 (2.4%)" "malate metabolic process (33.3%) lactate metabolic process (1.2%)" membrane (1.2%) "malate dehydrogenase activity (29.8%) oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (29.8%) malate dehydrogenase (decarboxylating) (NADP+) activity (2.4%)" "IPR001236 (16.8%) IPR001557 (16.8%) IPR015955 (16.8%)" "Lactate/malate dehydrogenase, N-terminal (16.8%) L-lactate/malate dehydrogenase (16.8%) Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal (16.8%)" QLNPHAYEVAYQYQNLWAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.2%) GO:0009341 (25.2%) "GO:0004565 (25.2%) GO:0030246 (24.5%)" lactose catabolic process (25.2%) beta-galactosidase complex (25.2%) "beta-galactosidase activity (25.2%) carbohydrate binding (24.5%)" "IPR004199 (7.2%) IPR006102 (7.2%) IPR006103 (7.2%)" "Beta galactosidase small chain/ domain 5 (7.2%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (7.2%) Glycoside hydrolase family 2, catalytic domain (7.2%)" LSVLTYHSLEDR Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.1.1.199 (100%) 16S rRNA (cytosine(1402)-N(4))-methyltransferase (100%) GO:0070475 (33.3%) GO:0005737 (33.3%) GO:0071424 (33.3%) rRNA base methylation (33.3%) cytoplasm (33.3%) rRNA (cytosine-N4-)-methyltransferase activity (33.3%) "IPR002903 (33.6%) IPR029063 (33.3%) IPR023397 (33%)" "Ribosomal RNA small subunit methyltransferase H (33.6%) S-adenosyl-L-methionine-dependent methyltransferase superfamily (33.3%) S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily (33%)" QFLDKDSQVCGYEYVHLGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GEPGTGDVVQAVTHMR Bacteria Bacteria 4.3.3.6 (100%) pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (100%) "GO:0006520 (25%) GO:0008615 (25%) GO:0042823 (25%)" "GO:0036381 (24.3%) GO:0016843 (0.7%)" "amino acid metabolic process (25%) pyridoxine biosynthetic process (25%) pyridoxal phosphate biosynthetic process (25%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (24.3%) amine-lyase activity (0.7%)" "IPR001852 (25%) IPR011060 (25%) IPR013785 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Ribulose-phosphate binding barrel (25%) Aldolase-type TIM barrel (25%)" VVPAEKDLADFAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002909 (33.3%) IPR013783 (33.3%) IPR014756 (33.3%)" "IPT domain (33.3%) Immunoglobulin-like fold (33.3%) Immunoglobulin E-set (33.3%)" AANAGGVAVSGLEMSQNSER Bacteria Bacteria 1.4.1.4 (100%) glutamate dehydrogenase (NADP(+)) (100%) GO:0006537 (25.2%) GO:0005829 (25.2%) "GO:0004354 (25.2%) GO:0000166 (24.3%)" glutamate biosynthetic process (25.2%) cytosol (25.2%) "glutamate dehydrogenase (NADP+) activity (25.2%) nucleotide binding (24.3%)" "IPR006095 (11.2%) IPR006096 (11.2%) IPR006097 (11.2%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.2%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.2%)" VFYENNAHAYNK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.5%) IPR008969 (12.5%) IPR012910 (12.5%)" "TonB-dependent receptor-like, beta-barrel (12.5%) Carboxypeptidase-like, regulatory domain superfamily (12.5%) TonB-dependent receptor, plug domain (12.5%)" EYDDLSGLSGLFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR045741 (50%) IPR047799 (50%)" "Type IX secretion system protein PorV (50%) Type IX secretion system, outer membrane channel protein PorV (50%)" HYNVECVCTTDDPLDDLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.6%) IPR032466 (47.4%)" "Uronate isomerase (52.6%) Metal-dependent hydrolase (47.4%)" ANLFFNNSGWGWK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri LDFNSTSFSHPK Pseudomonadati Bacteria Pseudomonadati 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (19.9%) "GO:0008740 (20%) GO:0030145 (20%) GO:0016853 (0.1%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (19.9%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%) isomerase activity (0.1%)" "IPR009308 (33.3%) IPR036237 (33.3%) IPR050337 (33.3%)" "Rhamnose isomerase (33.3%) Xylose isomerase-like superfamily (33.3%) L-rhamnose isomerase (33.3%)" VPDEESELPHALYGAK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.1.-.- (100%) Acting on ester bonds (100%) GO:0006402 (19.5%) "GO:0005886 (19.1%) GO:0016020 (0.7%)" "GO:0003723 (20.5%) GO:0016787 (20.5%) GO:0004521 (18.8%)" mRNA catabolic process (19.5%) "plasma membrane (19.1%) membrane (0.7%)" "RNA binding (20.5%) hydrolase activity (20.5%) RNA endonuclease activity (18.8%)" "IPR006674 (12.8%) IPR006675 (12.8%) IPR003607 (12.6%)" "HD domain (12.8%) HDIG domain (12.8%) HD/PDEase domain (12.6%)" YALEHLPANAYPK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.5%) IPR033985 (34.5%) IPR011990 (31%)" "RagB/SusD domain (34.5%) SusD-like, N-terminal (34.5%) Tetratricopeptide-like helical domain superfamily (31%)" EFSYSNYQQCYTLPEDADREK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR002068 (33.3%) IPR008978 (33.3%) IPR031107 (33.3%)" "Alpha crystallin/Hsp20 domain (33.3%) HSP20-like chaperone (33.3%) Small heat shock protein (33.3%)" RGENGAPEALSFAVPFAELR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006412 (25%) GO:0022625 (25%) "GO:0003735 (25%) GO:0008097 (25%)" translation (25%) cytosolic large ribosomal subunit (25%) "structural constituent of ribosome (25%) 5S rRNA binding (25%)" "IPR001021 (14.3%) IPR011035 (14.3%) IPR020056 (14.3%)" "Ribosomal protein bL25, long-form (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily (14.3%) Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal (14.3%)" QPVKEPLQTGLK Bacteria Bacteria "7.1.2.2 (99.1%) 3.6.3.14 (0.9%)" "H(+)-transporting two-sector ATPase (99.1%) Transferred entry: 7.1.2.2 (0.9%)" GO:0015986 (0.1%) "GO:0045259 (19.2%) GO:0005886 (18.3%)" "GO:0005524 (19.2%) GO:0043531 (19.2%) GO:0046933 (19.2%)" proton motive force-driven ATP synthesis (0.1%) "proton-transporting ATP synthase complex (19.2%) plasma membrane (18.3%)" "ATP binding (19.2%) ADP binding (19.2%) proton-transporting ATP synthase activity, rotational mechanism (19.2%)" "IPR005294 (10.1%) IPR027417 (10.1%) IPR000194 (10.1%)" "ATP synthase, F1 complex, alpha subunit (10.1%) P-loop containing nucleoside triphosphate hydrolase (10.1%) ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.1%)" LTVEDFPAFLLVDDKGNDFFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.9%) "GO:0046872 (24.9%) GO:0051539 (24.9%) GO:0004333 (23.8%)" tricarboxylic acid cycle (24.9%) "metal ion binding (24.9%) 4 iron, 4 sulfur cluster binding (24.9%) fumarate hydratase activity (23.8%)" "IPR004647 (18.8%) IPR051208 (18.8%) IPR004646 (18.4%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (18.8%) Class-I Fumarase/Tartrate Dehydratase (18.8%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (18.4%)" DDAQNYVYPMPLESAGKDDVYVGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 1.2.1.11 (100%) aspartate-semialdehyde dehydrogenase (100%) "GO:0009088 (11.1%) GO:0009089 (11.1%) GO:0009097 (11.1%)" "GO:0004073 (11.1%) GO:0046983 (11.1%) GO:0050661 (11.1%)" "threonine biosynthetic process (11.1%) lysine biosynthetic process via diaminopimelate (11.1%) isoleucine biosynthetic process (11.1%)" "aspartate-semialdehyde dehydrogenase activity (11.1%) protein dimerization activity (11.1%) NADP binding (11.1%)" "IPR000534 (20.4%) IPR005986 (20.4%) IPR012280 (20.4%)" "Semialdehyde dehydrogenase, NAD-binding (20.4%) Aspartate-semialdehyde dehydrogenase, beta-type (20.4%) Semialdehyde dehydrogenase, dimerisation domain (20.4%)" SLFESFK root "2.7.11.30 (73.2%) 2.7.13.3 (4.2%) 4.1.1.71 (4.2%)" "receptor protein serine/threonine kinase (73.2%) histidine kinase (4.2%) 2-oxoglutarate decarboxylase (4.2%)" "GO:0071363 (4.4%) GO:0006915 (3.1%) GO:0015833 (2%)" "GO:0005886 (7%) GO:0043235 (3.4%) GO:0016020 (3.1%)" "GO:0005524 (7.9%) GO:0004675 (3.9%) GO:0046872 (3.7%)" "cellular response to growth factor stimulus (4.4%) apoptotic process (3.1%) peptide transport (2%)" "plasma membrane (7%) receptor complex (3.4%) membrane (3.1%)" "ATP binding (7.9%) transmembrane receptor protein serine/threonine kinase activity (3.9%) metal ion binding (3.7%)" "IPR011009 (4.6%) IPR000719 (4.6%) IPR000333 (4.5%)" "Protein kinase-like domain superfamily (4.6%) Protein kinase domain (4.6%) Ser/Thr protein kinase, TGFB receptor (4.5%)" YMLTGTFR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006826 (1.9%) GO:0009279 (98.1%) iron ion transport (1.9%) cell outer membrane (98.1%) "IPR036942 (13.6%) IPR039426 (13.6%) IPR023996 (13.4%)" "TonB-dependent receptor-like, beta-barrel domain superfamily (13.6%) TonB-dependent receptor-like (13.6%) TonB-dependent outer membrane protein, SusC/RagA (13.4%)" MGCDNFSPDDR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" DAKDFDDALSLQR Bacteroidota Bacteria Pseudomonadati Bacteroidota 3.1.13.1 (100%) exoribonuclease II (100%) GO:0006402 (24.8%) GO:0005829 (24.8%) "GO:0003723 (24.8%) GO:0008859 (24.1%) GO:0004527 (0.8%)" mRNA catabolic process (24.8%) cytosol (24.8%) "RNA binding (24.8%) exoribonuclease II activity (24.1%) exonuclease activity (0.8%)" "IPR001900 (12.7%) IPR040476 (12.7%) IPR050180 (12.7%)" "Ribonuclease II/R (12.7%) RNase II/RNase R, cold shock domain (12.7%) RNR Ribonuclease (12.7%)" LVGQQLYK root 5.2.1.8 (100%) peptidylprolyl isomerase (100%) "GO:0015031 (13.2%) GO:0043335 (13.2%) GO:0051083 (13.2%)" "GO:0005737 (4.6%) GO:0044611 (2.6%) GO:0005634 (0.7%)" "GO:0003755 (13.2%) GO:0043022 (13.2%) GO:0044183 (13.2%)" "protein transport (13.2%) protein unfolding (13.2%) 'de novo' cotranslational protein folding (13.2%)" "cytoplasm (4.6%) nuclear pore inner ring (2.6%) nucleus (0.7%)" "peptidyl-prolyl cis-trans isomerase activity (13.2%) ribosome binding (13.2%) protein folding chaperone (13.2%)" "IPR005215 (16.1%) IPR008881 (16.1%) IPR027304 (15.3%)" "Trigger factor (16.1%) Trigger factor, ribosome-binding, bacterial (16.1%) Trigger factor/SurA domain superfamily (15.3%)" NWEKPLTLAR Bacteria Bacteria 1.1.1.42 (100%) isocitrate dehydrogenase (NADP(+)) (100%) "GO:0006099 (20.3%) GO:0006102 (20.3%)" "GO:0004450 (20.3%) GO:0000287 (19%) GO:0051287 (19%)" "tricarboxylic acid cycle (20.3%) isocitrate metabolic process (20.3%)" "isocitrate dehydrogenase (NADP+) activity (20.3%) magnesium ion binding (19%) NAD binding (19%)" "IPR004790 (34%) IPR024084 (34%) IPR019818 (31.9%)" "Isocitrate dehydrogenase NADP-dependent (34%) Isopropylmalate dehydrogenase-like domain (34%) Isocitrate/isopropylmalate dehydrogenase, conserved site (31.9%)" GYMDNVLSSMLAAR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34%) "GO:0004222 (34%) GO:0046872 (32%)" proteolysis (34%) "metalloendopeptidase activity (34%) metal ion binding (32%)" "IPR001431 (20.2%) IPR007863 (20.2%) IPR011765 (20.2%)" "Peptidase M16, zinc-binding site (20.2%) Peptidase M16, C-terminal (20.2%) Peptidase M16, N-terminal (20.2%)" NHSVTNMLNASFTGGGEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" KPGSLGACSYPAK Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0006412 (24.9%) "GO:0022625 (24.8%) GO:0005840 (0.2%) GO:1990904 (0.1%)" "GO:0003735 (24.9%) GO:0019843 (24.9%)" translation (24.9%) "cytosolic large ribosomal subunit (24.8%) ribosome (0.2%) ribonucleoprotein complex (0.1%)" "structural constituent of ribosome (24.9%) rRNA binding (24.9%)" "IPR000597 (25%) IPR009000 (25%) IPR019926 (25%)" "Large ribosomal subunit protein uL3 (25%) Translation protein, beta-barrel domain superfamily (25%) Large ribosomal subunit protein uL3, conserved site (25%)" CFVLMTR root "GO:0071709 (39%) GO:0008654 (7.1%)" "GO:0009279 (32.3%) GO:0019867 (7.4%) GO:0016020 (7.1%)" GO:0016780 (7.1%) "membrane assembly (39%) phospholipid biosynthetic process (7.1%)" "cell outer membrane (32.3%) outer membrane (7.4%) membrane (7.1%)" phosphotransferase activity, for other substituted phosphate groups (7.1%) "IPR010827 (22.2%) IPR034746 (22.2%) IPR023707 (21.8%)" "POTRA domain, BamA/TamA-like (22.2%) POTRA domain (22.2%) Outer membrane protein assembly factor BamA (21.8%)" CLQLAFDALR Pseudomonadati Bacteria Pseudomonadati 1.1.1.267 (100%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase (100%) GO:0051484 (22.9%) "GO:0030145 (22.9%) GO:0030604 (22.9%) GO:0070402 (22.9%)" isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process (22.9%) "manganese ion binding (22.9%) 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity (22.9%) NADPH binding (22.9%)" "IPR003821 (17.1%) IPR026877 (17.1%) IPR036169 (17.1%)" "1-deoxy-D-xylulose 5-phosphate reductoisomerase (17.1%) DXP reductoisomerase, C-terminal domain (17.1%) DXP reductoisomerase, C-terminal domain superfamily (17.1%)" ELYTLLSDHSHTPYDK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.21.92 (100%) endopeptidase Clp (100%) GO:0006515 (16.7%) "GO:0005737 (16.7%) GO:0009368 (16.7%)" "GO:0004176 (16.7%) GO:0004252 (16.7%) GO:0051117 (16.7%)" protein quality control for misfolded or incompletely synthesized proteins (16.7%) "cytoplasm (16.7%) endopeptidase Clp complex (16.7%)" "ATP-dependent peptidase activity (16.7%) serine-type endopeptidase activity (16.7%) ATPase binding (16.7%)" "IPR001907 (25.9%) IPR023562 (25.9%) IPR029045 (25.9%)" "ATP-dependent Clp protease proteolytic subunit (25.9%) Clp protease proteolytic subunit /Translocation-enhancing protein TepA (25.9%) ClpP/crotonase-like domain superfamily (25.9%)" KPSEDEPTSALAFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (20.2%) GO:0005737 (19.7%) "GO:0003746 (20.2%) GO:0005525 (20.2%) GO:0003924 (19.7%)" ribosome disassembly (20.2%) cytoplasm (19.7%) "translation elongation factor activity (20.2%) GTP binding (20.2%) GTPase activity (19.7%)" "IPR000640 (6.3%) IPR004161 (6.3%) IPR005517 (6.3%)" "Elongation factor EFG, domain V-like (6.3%) Translation elongation factor EFTu-like, domain 2 (6.3%) Translation elongation factor EFG/EF2, domain IV (6.3%)" NNPLLLGEPGTGK root "GO:0034605 (20%) GO:0042026 (15.3%) GO:0006508 (2.2%)" "GO:0005737 (20%) GO:0005829 (0%)" "GO:0005524 (20%) GO:0016887 (20%) GO:0008233 (2.2%)" "cellular response to heat (20%) protein refolding (15.3%) proteolysis (2.2%)" "cytoplasm (20%) cytosol (0%)" "ATP binding (20%) ATP hydrolysis activity (20%) peptidase activity (2.2%)" "IPR050130 (8.5%) IPR003593 (8.5%) IPR003959 (8.5%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.5%) AAA+ ATPase domain (8.5%) ATPase, AAA-type, core (8.5%)" LLQELGVK root "6.3.1.5 (62.6%) 2.5.1.7 (16.9%) 3.1.26.4 (8.7%)" "NAD(+) synthase (62.6%) UDP-N-acetylglucosamine 1-carboxyvinyltransferase (16.9%) ribonuclease H (8.7%)" "GO:0009435 (8.1%) GO:0051301 (2.3%) GO:0008360 (2.2%)" "GO:0005737 (12.2%) GO:0032299 (0.8%) GO:0005634 (0.8%)" "GO:0005524 (9%) GO:0046872 (8.5%) GO:0003952 (8%)" "NAD+ biosynthetic process (8.1%) cell division (2.3%) regulation of cell shape (2.2%)" "cytoplasm (12.2%) ribonuclease H2 complex (0.8%) nucleus (0.8%)" "ATP binding (9%) metal ion binding (8.5%) NAD+ synthase (glutamine-hydrolyzing) activity (8%)" "IPR014729 (9.6%) IPR022310 (9.3%) IPR003694 (9.2%)" "Rossmann-like alpha/beta/alpha sandwich fold (9.6%) NAD/GMP synthase (9.3%) NAD(+) synthetase (9.2%)" LCNQSFVNYLENVYHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016757 (85.7%) GO:0016740 (14.3%)" "glycosyltransferase activity (85.7%) transferase activity (14.3%)" "IPR000836 (25.6%) IPR017932 (25.6%) IPR029055 (24.4%)" "Phosphoribosyltransferase domain (25.6%) Glutamine amidotransferase type 2 domain (25.6%) Nucleophile aminohydrolases, N-terminal (24.4%)" DMQDTFFLEK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0006432 (16.5%) GO:0043039 (0.1%)" "GO:0005737 (16.5%) GO:0016020 (0.1%)" "GO:0000049 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" "phenylalanyl-tRNA aminoacylation (16.5%) tRNA aminoacylation (0.1%)" "cytoplasm (16.5%) membrane (0.1%)" "tRNA binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002319 (14.5%) IPR006195 (14.5%) IPR045864 (14.5%)" "Phenylalanyl-tRNA synthetase (14.5%) Aminoacyl-tRNA synthetase, class II (14.5%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.5%)" TEQLLAGVFYK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (20.5%) IPR012910 (20.5%) IPR008969 (19.5%)" "TonB-dependent receptor-like, beta-barrel (20.5%) TonB-dependent receptor, plug domain (20.5%) Carboxypeptidase-like, regulatory domain superfamily (19.5%)" VGMGYQGEENVFKGNDYER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.6%) IPR012910 (12.6%) IPR023996 (12.6%)" "TonB-dependent receptor-like, beta-barrel (12.6%) TonB-dependent receptor, plug domain (12.6%) TonB-dependent outer membrane protein, SusC/RagA (12.6%)" VLLKDDAQLTPNYQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" LAEEDPTFTVR Bacteria Bacteria "GO:0032790 (20.4%) GO:0006412 (0.4%)" "GO:0005737 (19.3%) GO:0005759 (0%)" "GO:0005525 (20.4%) GO:0003746 (19.9%) GO:0003924 (19.6%)" "ribosome disassembly (20.4%) translation (0.4%)" "cytoplasm (19.3%) mitochondrial matrix (0%)" "GTP binding (20.4%) translation elongation factor activity (19.9%) GTPase activity (19.6%)" "IPR041095 (6.4%) IPR009000 (6.4%) IPR035647 (6.4%)" "Elongation Factor G, domain II (6.4%) Translation protein, beta-barrel domain superfamily (6.4%) EF-G domain III/V-like (6.4%)" ESFSATHNGWK Bacteria Bacteria "2.7.1.92 (64.7%) 2.7.1.45 (35.3%)" "5-dehydro-2-deoxygluconokinase (64.7%) 2-dehydro-3-deoxygluconokinase (35.3%)" "GO:0016301 (85.2%) GO:0047590 (8.7%) GO:0008673 (6.1%)" "kinase activity (85.2%) 5-dehydro-2-deoxygluconokinase activity (8.7%) 2-dehydro-3-deoxygluconokinase activity (6.1%)" "IPR029056 (33.5%) IPR011611 (33.2%) IPR052700 (33.2%)" "Ribokinase-like (33.5%) Carbohydrate kinase PfkB (33.2%) Carbohydrate kinase PfkB-like (33.2%)" FGAPQLTK root 5.6.1.7 (100%) chaperonin ATPase (100%) GO:0042026 (17.2%) GO:0005737 (16.1%) "GO:0005524 (17.2%) GO:0140662 (17.2%) GO:0016853 (16.2%)" protein refolding (17.2%) cytoplasm (16.1%) "ATP binding (17.2%) ATP-dependent protein folding chaperone (17.2%) isomerase activity (16.2%)" "IPR001844 (16.9%) IPR002423 (16.9%) IPR027413 (16.7%)" "Chaperonin Cpn60/GroEL (16.9%) Chaperonin Cpn60/GroEL/TCP-1 family (16.9%) GroEL-like equatorial domain superfamily (16.7%)" YTELFLDYAEAANEAWGPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (35.4%) IPR011990 (33.3%) IPR033985 (31.3%)" "RagB/SusD domain (35.4%) Tetratricopeptide-like helical domain superfamily (33.3%) SusD-like, N-terminal (31.3%)" TLQVLNLLR root 3.4.22.- (100%) Cysteine endopeptidases (100%) "GO:0016226 (87.2%) GO:0006508 (2.6%) GO:0000160 (1.3%)" "GO:0005886 (2.6%) GO:0016020 (1.3%)" "GO:0008233 (2.6%) GO:0016787 (1.3%) GO:0016791 (1.3%)" "iron-sulfur cluster assembly (87.2%) proteolysis (2.6%) phosphorelay signal transduction system (1.3%)" "plasma membrane (2.6%) membrane (1.3%)" "peptidase activity (2.6%) hydrolase activity (1.3%) phosphatase activity (1.3%)" "IPR045595 (19.2%) IPR055346 (19.2%) IPR000825 (18.9%)" "SUF system FeS cluster assembly, SufBD, N-terminal (19.2%) SUF system FeS cluster assembly, SufBD (19.2%) SUF system FeS cluster assembly, SufBD core domain (18.9%)" NVALATVNQNCK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0006680 (33.3%) GO:0016020 (33.3%) GO:0004348 (33.3%) glucosylceramide catabolic process (33.3%) membrane (33.3%) glucosylceramidase activity (33.3%) "IPR001139 (20.6%) IPR033452 (20.6%) IPR033453 (20.6%)" "Glycoside hydrolase family 30 (20.6%) Glycosyl hydrolase family 30, beta sandwich domain (20.6%) Glycosyl hydrolase family 30, TIM-barrel domain (20.6%)" NLDFAFGLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR032339 (100%) Domain of unknown function DUF4859 (100%) AAEELFTGHLSSGAMNDLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.24.- (100%) Metalloendopeptidases (100%) "GO:0006508 (12.5%) GO:0030163 (12.5%)" GO:0005886 (12.5%) "GO:0004176 (12.5%) GO:0004222 (12.5%) GO:0005524 (12.5%)" "proteolysis (12.5%) protein catabolic process (12.5%)" plasma membrane (12.5%) "ATP-dependent peptidase activity (12.5%) metalloendopeptidase activity (12.5%) ATP binding (12.5%)" "IPR000642 (10.1%) IPR003593 (10.1%) IPR003959 (10.1%)" "Peptidase M41 (10.1%) AAA+ ATPase domain (10.1%) ATPase, AAA-type, core (10.1%)" LNWGVPFYELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR014825 (50%) IPR016024 (50%)" "DNA alkylation repair enzyme (50%) Armadillo-type fold (50%)" YFDPEKNESYVPYDVETSLGVDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.5%) GO:0015966 (12.5%)" "GO:0005737 (12.5%) GO:0070062 (12.5%) GO:1990742 (12.5%)" "GO:0004081 (12.5%) GO:0004820 (12.5%) GO:0005524 (12.5%)" "glycyl-tRNA aminoacylation (12.5%) diadenosine tetraphosphate biosynthetic process (12.5%)" "cytoplasm (12.5%) extracellular exosome (12.5%) microvesicle (12.5%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.5%) glycine-tRNA ligase activity (12.5%) ATP binding (12.5%)" "IPR002314 (11.5%) IPR004154 (11.5%) IPR006195 (11.5%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (11.5%) Anticodon-binding (11.5%) Aminoacyl-tRNA synthetase, class II (11.5%)" NSEALDKYLVELGR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006352 (33.3%) "GO:0003677 (33.3%) GO:0016987 (33.3%)" DNA-templated transcription initiation (33.3%) "DNA binding (33.3%) sigma factor activity (33.3%)" "IPR007627 (11.5%) IPR009042 (11.5%) IPR014284 (11.5%)" "RNA polymerase sigma-70 region 2 (11.5%) RNA polymerase sigma-70 region 1.2 (11.5%) RNA polymerase sigma-70-like domain (11.5%)" EALLLTALGK root GO:0015920 (3.8%) "GO:0005886 (34.6%) GO:0045259 (30.8%)" GO:0046933 (30.8%) lipopolysaccharide transport (3.8%) "plasma membrane (34.6%) proton-transporting ATP synthase complex (30.8%)" proton-transporting ATP synthase activity, rotational mechanism (30.8%) "IPR000711 (47.1%) IPR026015 (47.1%) IPR047817 (5.9%)" "ATPase, OSCP/delta subunit (47.1%) F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily (47.1%) ABC-2 type transporter, transmembrane domain, bacterial-type (5.9%)" LNVLAPPSANNR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.-.- (100%) Acting on ester bonds (100%) "GO:0005576 (49.2%) GO:0005737 (49.2%)" GO:0016787 (1.6%) "extracellular region (49.2%) cytoplasm (49.2%)" hydrolase activity (1.6%) "IPR003284 (18.9%) IPR028994 (15.9%) IPR022045 (13.4%)" "Salmonella virulence plasmid 65kDa B protein (18.9%) Integrin alpha, N-terminal (15.9%) Insecticide toxin TcdB middle/N-terminal (13.4%)" AVLESVGLKDVLAK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "GO:0006412 (16.7%) GO:0042254 (15.1%)" "GO:0005737 (16.7%) GO:0015935 (15.1%) GO:0005840 (1.6%)" "GO:0003735 (16.7%) GO:0019843 (15.1%) GO:0003723 (1.6%)" "translation (16.7%) ribosome biogenesis (15.1%)" "cytoplasm (16.7%) small ribosomal subunit (15.1%) ribosome (1.6%)" "structural constituent of ribosome (16.7%) rRNA binding (15.1%) RNA binding (1.6%)" "IPR000851 (14.8%) IPR005324 (14.8%) IPR013810 (14.8%)" "Small ribosomal subunit protein uS5 (14.8%) Small ribosomal subunit protein uS5, C-terminal (14.8%) Small ribosomal subunit protein uS5, N-terminal (14.8%)" TTLSNLLANELGVGFK Bacteroidota Bacteria Pseudomonadati Bacteroidota "3.6.4.- (87.4%) 3.6.4.12 (12.3%) 3.6.1.- (0.3%)" "Acting on ATP; involved in cellular and subcellular movement (87.4%) DNA helicase (12.3%) In phosphorus-containing anhydrides (0.3%)" "GO:0006281 (12.6%) GO:0006310 (12.6%)" "GO:0005737 (12.4%) GO:0048476 (11.9%) GO:0016020 (0.1%)" "GO:0005524 (12.6%) GO:0009378 (12.6%) GO:0000400 (11.9%)" "DNA repair (12.6%) DNA recombination (12.6%)" "cytoplasm (12.4%) Holliday junction resolvase complex (11.9%) membrane (0.1%)" "ATP binding (12.6%) four-way junction helicase activity (12.6%) four-way junction DNA binding (11.9%)" "IPR004605 (12.7%) IPR008824 (12.7%) IPR027417 (12.7%)" "Holliday junction branch migration complex subunit RuvB (12.7%) RuvB-like, AAA+ ATPase domain (12.7%) P-loop containing nucleoside triphosphate hydrolase (12.7%)" AGVLGMDSWEYANLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0006811 (12.9%) "GO:0009279 (58.1%) GO:0046930 (12.9%) GO:0016020 (3.2%)" GO:0015288 (12.9%) monoatomic ion transport (12.9%) "cell outer membrane (58.1%) pore complex (12.9%) membrane (3.2%)" porin activity (12.9%) "IPR011250 (26.1%) IPR006665 (16.5%) IPR050330 (16.5%)" "Outer membrane protein/outer membrane enzyme PagP, beta-barrel (26.1%) OmpA-like domain (16.5%) Bacterial Outer Membrane Structural/Functional (16.5%)" DNYVEAWTK Bacteria Bacteria GO:0055085 (14.3%) "GO:0009279 (71.4%) GO:0005886 (14.3%)" transmembrane transport (14.3%) "cell outer membrane (71.4%) plasma membrane (14.3%)" "IPR011990 (29.4%) IPR012944 (29.4%) IPR033985 (29.4%)" "Tetratricopeptide-like helical domain superfamily (29.4%) RagB/SusD domain (29.4%) SusD-like, N-terminal (29.4%)" ATYTPVLQDDGTYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR008969 (12.2%) IPR012910 (12.2%) IPR023996 (12.2%)" "Carboxypeptidase-like, regulatory domain superfamily (12.2%) TonB-dependent receptor, plug domain (12.2%) TonB-dependent outer membrane protein, SusC/RagA (12.2%)" LVNSQGEPLPGAVVNVAEESR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (15%) IPR023996 (15%) IPR023997 (15%)" "TonB-dependent receptor, plug domain (15%) TonB-dependent outer membrane protein, SusC/RagA (15%) TonB-dependent outer membrane protein SusC/RagA, conserved site (15%)" LLSFLDASPVNFLAVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.4.11.- (100%) Aminopeptidases (100%) GO:0006508 (20.4%) GO:0005737 (19.4%) "GO:0004177 (20.4%) GO:0008270 (20.4%) GO:0008237 (19.4%)" proteolysis (20.4%) cytoplasm (19.4%) "aminopeptidase activity (20.4%) zinc ion binding (20.4%) metallopeptidase activity (19.4%)" "IPR001948 (51.2%) IPR023358 (48.8%)" "Peptidase M18 (51.2%) Peptidase M18, domain 2 (48.8%)" YLMEHVDGLDK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" LTEQLWNLPAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.6.1.16 (100%) glutamine--fructose-6-phosphate transaminase (isomerizing) (100%) "GO:0006002 (12.6%) GO:0006047 (12.6%) GO:0006487 (12.6%)" GO:0005829 (12.6%) "GO:0004360 (12.6%) GO:0097367 (12.6%)" "fructose 6-phosphate metabolic process (12.6%) UDP-N-acetylglucosamine metabolic process (12.6%) protein N-linked glycosylation (12.6%)" cytosol (12.6%) "glutamine-fructose-6-phosphate transaminase (isomerizing) activity (12.6%) carbohydrate derivative binding (12.6%)" "IPR001347 (13.1%) IPR035466 (13.1%) IPR035490 (13.1%)" "SIS domain (13.1%) GlmS/AgaS, SIS domain 1 (13.1%) GlmS/FrlB, SIS domain 2 (13.1%)" FPEYLQTHLER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.5%) "GO:0009341 (25.5%) GO:0016020 (0.9%)" "GO:0004565 (25.5%) GO:0030246 (22.6%)" lactose catabolic process (25.5%) "beta-galactosidase complex (25.5%) membrane (0.9%)" "beta-galactosidase activity (25.5%) carbohydrate binding (22.6%)" "IPR006103 (8.2%) IPR050347 (8.2%) IPR004199 (7.9%)" "Glycoside hydrolase family 2, catalytic domain (8.2%) Bacterial Beta-galactosidase (8.2%) Beta galactosidase small chain/ domain 5 (7.9%)" YLSMMQEVAQGKDNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20%) IPR001972 (20%) IPR018080 (20%)" "Band 7 domain (20%) Stomatin/HflK family (20%) Band 7/stomatin-like, conserved site (20%)" VYATGLLVK root GO:0016020 (100%) membrane (100%) "IPR043744 (96.4%) IPR004302 (3.6%)" "Domain of unknown function DUF5689 (96.4%) Cellulose/chitin-binding protein, N-terminal (3.6%)" ESYLMHHEELESLVK Pseudomonadati Bacteria Pseudomonadati 1.5.1.7 (100%) saccharopine dehydrogenase (NAD(+), L-lysine-forming) (100%) GO:0016020 (14.3%) GO:0004754 (85.7%) membrane (14.3%) saccharopine dehydrogenase (NAD+, L-lysine-forming) activity (85.7%) "IPR032095 (34%) IPR005097 (33%) IPR036291 (33%)" "Saccharopine dehydrogenase-like, C-terminal (34%) Saccharopine dehydrogenase, NADP binding domain (33%) NAD(P)-binding domain superfamily (33%)" NPSLALTDFFK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.2.1.23 (100%) beta-galactosidase (100%) GO:0005990 (25.3%) GO:0009341 (25.3%) "GO:0004565 (25.3%) GO:0030246 (24.2%)" lactose catabolic process (25.3%) beta-galactosidase complex (25.3%) "beta-galactosidase activity (25.3%) carbohydrate binding (24.2%)" "IPR004199 (6.8%) IPR006102 (6.8%) IPR006103 (6.8%)" "Beta galactosidase small chain/ domain 5 (6.8%) Glycoside hydrolase family 2, immunoglobulin-like beta-sandwich (6.8%) Glycoside hydrolase family 2, catalytic domain (6.8%)" FYPADFLNEGVDQTR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.3%) GO:0005737 (14.3%) "GO:0000049 (14.3%) GO:0004822 (14.3%) GO:0005524 (14.3%)" isoleucyl-tRNA aminoacylation (14.3%) cytoplasm (14.3%) "tRNA binding (14.3%) isoleucine-tRNA ligase activity (14.3%) ATP binding (14.3%)" "IPR002300 (12.6%) IPR002301 (12.6%) IPR013155 (12.6%)" "Aminoacyl-tRNA synthetase, class Ia (12.6%) Isoleucine-tRNA ligase (12.6%) Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding (12.6%)" DGQALGLGAGQQSR Bacteria Bacteria "2.1.2.3 (95.1%) 3.5.4.10 (4.9%)" "phosphoribosylaminoimidazolecarboxamide formyltransferase (95.1%) IMP cyclohydrolase (4.9%)" "GO:0006189 (24.9%) GO:0006164 (0%)" "GO:0005829 (24.9%) GO:0005840 (0%)" "GO:0003937 (25%) GO:0004643 (25%) GO:0016740 (0.1%)" "'de novo' IMP biosynthetic process (24.9%) purine nucleotide biosynthetic process (0%)" "cytosol (24.9%) ribosome (0%)" "IMP cyclohydrolase activity (25%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (25%) transferase activity (0.1%)" "IPR002695 (25.1%) IPR016193 (25%) IPR024051 (25%)" "Bifunctional purine biosynthesis protein PurH-like (25.1%) Cytidine deaminase-like (25%) AICAR transformylase, duplicated domain superfamily (25%)" LALNSAVYTDGQVKDYQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (50%) IPR012944 (50%)" "Tetratricopeptide-like helical domain superfamily (50%) RagB/SusD domain (50%)" YKDNFVLATNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR015943 (100%) WD40/YVTN repeat-like-containing domain superfamily (100%) LFPDKPLTR root "GO:0006412 (19.6%) GO:0032543 (0.2%)" "GO:0022625 (18.3%) GO:0005840 (1.4%) GO:1990904 (1.3%)" "GO:0003735 (19.8%) GO:0019843 (19.8%) GO:0000049 (19.2%)" "translation (19.6%) mitochondrial translation (0.2%)" "cytosolic large ribosomal subunit (18.3%) ribosome (1.4%) ribonucleoprotein complex (1.3%)" "structural constituent of ribosome (19.8%) rRNA binding (19.8%) tRNA binding (19.2%)" "IPR000114 (20.1%) IPR016180 (20.1%) IPR036920 (20.1%)" "Large ribosomal subunit protein uL16, bacteria (20.1%) Large ribosomal subunit protein uL16 domain (20.1%) Large ribosomal subunit protein uL16 superfamily (20.1%)" SMLAWLK root "6.1.1.19 (96.3%) 3.2.1.17 (1.8%) 2.7.13.3 (0.5%)" "arginine--tRNA ligase (96.3%) lysozyme (1.8%) histidine kinase (0.5%)" "GO:0006420 (20.3%) GO:0009253 (0.4%) GO:0016052 (0.4%)" "GO:0005737 (20.5%) GO:0005886 (1%) GO:0005576 (0.4%)" "GO:0005524 (20.7%) GO:0004814 (20.3%) GO:0004842 (1.9%)" "arginyl-tRNA aminoacylation (20.3%) peptidoglycan catabolic process (0.4%) carbohydrate catabolic process (0.4%)" "cytoplasm (20.5%) plasma membrane (1%) extracellular region (0.4%)" "ATP binding (20.7%) arginine-tRNA ligase activity (20.3%) ubiquitin-protein transferase activity (1.9%)" "IPR001278 (11%) IPR001412 (11%) IPR035684 (11%)" "Arginine-tRNA ligase (11%) Aminoacyl-tRNA synthetase, class I, conserved site (11%) Arginyl-tRNA synthetase, catalytic core domain (11%)" LNLGHENPLDYQASLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.37 (100%) xylan 1,4-beta-xylosidase (100%) "GO:0031222 (24.5%) GO:0045493 (24.5%) GO:0005975 (1%)" "GO:0009044 (24.5%) GO:0046556 (24.5%) GO:0004553 (1%)" "arabinan catabolic process (24.5%) xylan catabolic process (24.5%) carbohydrate metabolic process (1%)" "xylan 1,4-beta-xylosidase activity (24.5%) alpha-L-arabinofuranosidase activity (24.5%) hydrolase activity, hydrolyzing O-glycosyl compounds (1%)" "IPR002772 (9.6%) IPR026891 (9.6%) IPR011658 (9.2%)" "Glycoside hydrolase family 3 C-terminal domain (9.6%) Fibronectin type III-like domain (9.6%) PA14 domain (9.2%)" VVLLTGAGDK root "4.1.3.36 (71.6%) 4.2.1.150 (15.4%) 4.2.1.17 (10.7%)" "1,4-dihydroxy-2-naphthoyl-CoA synthase (71.6%) short-chain-enoyl-CoA hydratase (15.4%) enoyl-CoA hydratase (10.7%)" "GO:0009234 (23.7%) GO:0006635 (13.9%) GO:0006631 (0.2%)" GO:0005829 (23.7%) "GO:0008935 (23.7%) GO:0016836 (7.9%) GO:0004300 (2.4%)" "menaquinone biosynthetic process (23.7%) fatty acid beta-oxidation (13.9%) fatty acid metabolic process (0.2%)" cytosol (23.7%) "1,4-dihydroxy-2-naphthoyl-CoA synthase activity (23.7%) hydro-lyase activity (7.9%) enoyl-CoA hydratase activity (2.4%)" "IPR001753 (22.3%) IPR029045 (22.3%) IPR014748 (21.4%)" "Enoyl-CoA hydratase/isomerase (22.3%) ClpP/crotonase-like domain superfamily (22.3%) Enoyl-CoA hydratase, C-terminal (21.4%)" GVTNVEWVQVGNETR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.89 (100%) arabinogalactan endo-beta-1,4-galactanase (100%) GO:0045490 (43.5%) "GO:0015926 (43.5%) GO:0031218 (12.9%)" pectin catabolic process (43.5%) "glucosidase activity (43.5%) arabinogalactan endo-1,4-beta-galactosidase activity (12.9%)" "IPR011683 (51.9%) IPR017853 (48.1%)" "Glycosyl hydrolase family 53 (51.9%) Glycoside hydrolase superfamily (48.1%)" NLGFTDSYADVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006865 (33.3%) GO:0043190 (33.3%) GO:0022857 (33.3%) amino acid transport (33.3%) ATP-binding cassette (ABC) transporter complex (33.3%) transmembrane transporter activity (33.3%) "IPR000515 (16.8%) IPR001638 (16.8%) IPR010065 (16.8%)" "ABC transporter type 1, transmembrane domain MetI-like (16.8%) Solute-binding protein family 3/N-terminal domain of MltF (16.8%) Amino acid ABC transporter, permease protein, 3-TM domain (16.8%)" ANPSANAQMMDQYTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005886 (50%) GO:0003755 (50%) plasma membrane (50%) peptidyl-prolyl cis-trans isomerase activity (50%) "IPR052029 (26.5%) IPR027304 (25.5%) IPR046357 (25.5%)" "Periplasmic chaperone PpiD (26.5%) Trigger factor/SurA domain superfamily (25.5%) Peptidyl-prolyl cis-trans isomerase domain superfamily (25.5%)" ALQSGTSHFLGQNFAK root 6.1.1.15 (100%) proline--tRNA ligase (100%) GO:0006433 (20%) "GO:0005737 (20%) GO:0017101 (20%) GO:0016020 (0.1%)" "GO:0004827 (20%) GO:0005524 (20%) GO:0016874 (0%)" prolyl-tRNA aminoacylation (20%) "cytoplasm (20%) aminoacyl-tRNA synthetase multienzyme complex (20%) membrane (0.1%)" "proline-tRNA ligase activity (20%) ATP binding (20%) ligase activity (0%)" "IPR004499 (11.4%) IPR045864 (11.3%) IPR036621 (11.2%)" "Proline-tRNA ligase, class IIa, archaeal-type (11.4%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (11.3%) Anticodon-binding domain superfamily (11.2%)" YSSYGGNTSMSESNAMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.1%) IPR033985 (34.1%) IPR011990 (31.7%)" "RagB/SusD domain (34.1%) SusD-like, N-terminal (34.1%) Tetratricopeptide-like helical domain superfamily (31.7%)" EKVSLPGYVFVEAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006354 (20.8%) GO:0031564 (20.8%) GO:0006353 (18.9%)" GO:0005829 (20.8%) "DNA-templated transcription elongation (20.8%) transcription antitermination (20.8%) DNA-templated transcription termination (18.9%)" cytosol (20.8%) "IPR006645 (13.1%) IPR036735 (13.1%) IPR043425 (13.1%)" "NusG-like, N-terminal (13.1%) NusG, N-terminal domain superfamily (13.1%) NusG-like (13.1%)" SWNVLEELAEK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.4.-.- (100%) Glycosyltransferases (100%) GO:0009103 (33.3%) GO:0005886 (33.3%) GO:0099621 (33.3%) lipopolysaccharide biosynthetic process (33.3%) plasma membrane (33.3%) undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity (33.3%) "IPR001173 (34.1%) IPR050256 (34.1%) IPR029044 (31.7%)" "Glycosyltransferase 2-like (34.1%) Glycosyltransferase 2 (34.1%) Nucleotide-diphospho-sugar transferases (31.7%)" YYDELPTTGDETGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (25%) "GO:0046872 (25%) GO:0051539 (25%) GO:0004333 (23.1%)" tricarboxylic acid cycle (25%) "metal ion binding (25%) 4 iron, 4 sulfur cluster binding (25%) fumarate hydratase activity (23.1%)" "IPR004646 (20.3%) IPR004647 (20.3%) IPR051208 (20.3%)" "Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (20.3%) Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (20.3%) Class-I Fumarase/Tartrate Dehydratase (20.3%)" VSKDGVLTLEESK Bacteria Bacteria 5.6.1.7 (100%) chaperonin ATPase (100%) "GO:0042026 (21.8%) GO:0009408 (0.1%)" GO:0005737 (10.2%) "GO:0140662 (21.8%) GO:0005524 (21.5%) GO:0016853 (14.4%)" "protein refolding (21.8%) response to heat (0.1%)" cytoplasm (10.2%) "ATP-dependent protein folding chaperone (21.8%) ATP binding (21.5%) isomerase activity (14.4%)" "IPR001844 (18.4%) IPR027409 (18.3%) IPR027413 (18.2%)" "Chaperonin Cpn60/GroEL (18.4%) GroEL-like apical domain superfamily (18.3%) GroEL-like equatorial domain superfamily (18.2%)" LNKEGLQEVYGLPDR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (100%) membrane (100%) IPR003672 (100%) CobN/magnesium chelatase (100%) YNLVDFDLGVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.11 (100%) serine--tRNA ligase (100%) "GO:0006434 (24.6%) GO:0006412 (0.6%)" GO:0005737 (24.6%) "GO:0004828 (24.6%) GO:0005524 (24.6%) GO:0000166 (0.6%)" "seryl-tRNA aminoacylation (24.6%) translation (0.6%)" cytoplasm (24.6%) "serine-tRNA ligase activity (24.6%) ATP binding (24.6%) nucleotide binding (0.6%)" "IPR010978 (14.4%) IPR015866 (14.4%) IPR042103 (14.4%)" "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm (14.4%) Serine-tRNA synthetase, type1, N-terminal (14.4%) Serine-tRNA synthetase, type1, N-terminal domain superfamily (14.4%)" SVYELNNLPNALEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005886 (50%) GO:0098552 (50%)" "plasma membrane (50%) side of membrane (50%)" "IPR001107 (20.4%) IPR036013 (20.4%) IPR050710 (20.4%)" "Band 7 domain (20.4%) Band 7/SPFH domain superfamily (20.4%) Band 7/mec-2 domain-containing protein (20.4%)" LADATALDPAAAVLYNYGPAWGVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR032149 (60%) IPR008160 (40%)" "Domain of unknown function DUF4988 (60%) Collagen triple helix repeat (40%)" EQVLLNTWYGGEMK Bacteria Bacteria 4.1.1.49 (100%) phosphoenolpyruvate carboxykinase (ATP) (100%) GO:0006094 (17.6%) GO:0005829 (17.6%) "GO:0004612 (17.6%) GO:0005524 (17.6%) GO:0046872 (17.3%)" gluconeogenesis (17.6%) cytosol (17.6%) "phosphoenolpyruvate carboxykinase (ATP) activity (17.6%) ATP binding (17.6%) metal ion binding (17.3%)" "IPR001272 (25.2%) IPR008210 (25.2%) IPR013035 (24.9%)" "Phosphoenolpyruvate carboxykinase, ATP-utilising (25.2%) Phosphoenolpyruvate carboxykinase, N-terminal (25.2%) Phosphoenolpyruvate carboxykinase, C-terminal (24.9%)" FDDNACVLLNNAGELR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia GO:0006412 (24.9%) "GO:0022625 (24.9%) GO:0005840 (0.2%)" "GO:0003735 (24.9%) GO:0070180 (24.9%)" translation (24.9%) "cytosolic large ribosomal subunit (24.9%) ribosome (0.2%)" "structural constituent of ribosome (24.9%) large ribosomal subunit rRNA binding (24.9%)" "IPR000218 (25%) IPR005745 (25%) IPR019972 (25%)" "Large ribosomal subunit protein uL14 (25%) Large ribosomal subunit protein uL14, bacteria (25%) Large ribosomal subunit protein uL14, conserved site (25%)" VTAASVEGVHLLVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0003677 (100%) DNA binding (100%) "IPR041607 (34.8%) IPR010992 (33.1%) IPR005902 (32%)" "HU domain fused to wHTH, Ig, or Glycine-rich motif (34.8%) Integration host factor (IHF)-like DNA-binding domain superfamily (33.1%) Putative DNA-binding protein, HU-related (32%)" AGLGAVELTPLYGVQGNDKNDLPYLSPK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0004553 (85.7%) GO:0016787 (14.3%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (85.7%) hydrolase activity (14.3%)" "IPR053161 (35%) IPR008979 (32.5%) IPR054593 (32.5%)" "Ulvan-degrading glycoside hydrolase (35%) Galactose-binding-like domain superfamily (32.5%) Beta-mannosidase-like, galactose-binding domain-like (32.5%)" GLNCSYAVYQDASGKAEEK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "1.1.1.86 (96%) 1.1.1.- (4%)" "ketol-acid reductoisomerase (NADP(+)) (96%) With NAD(+) or NADP(+) as acceptor (4%)" "GO:0009097 (22.3%) GO:0009099 (22.3%)" "GO:0004455 (22.3%) GO:0046872 (21.4%) GO:0016853 (11.7%)" "isoleucine biosynthetic process (22.3%) L-valine biosynthetic process (22.3%)" "ketol-acid reductoisomerase activity (22.3%) metal ion binding (21.4%) isomerase activity (11.7%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" ANEFSEQYHHNYSLLATPAEGLSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.17.4.2 (100%) ribonucleoside-triphosphate reductase (thioredoxin) (100%) "GO:0006260 (16.8%) GO:0009265 (16.8%)" GO:0031250 (16.8%) "GO:0004748 (16.8%) GO:0008998 (16.8%) GO:0005524 (16.2%)" "DNA replication (16.8%) 2'-deoxyribonucleotide biosynthetic process (16.8%)" anaerobic ribonucleoside-triphosphate reductase complex (16.8%) "ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (16.8%) ribonucleoside-triphosphate reductase (thioredoxin) activity (16.8%) ATP binding (16.2%)" "IPR012833 (50.8%) IPR005144 (49.2%)" "Ribonucleoside-triphosphate reductase, anaerobic (50.8%) ATP-cone domain (49.2%)" FLFLENEKLDGSLR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.13.18 (100%) cytosol non-specific dipeptidase (100%) GO:0006508 (25.5%) GO:0005829 (25.5%) "GO:0070573 (25.5%) GO:0046872 (23.6%)" proteolysis (25.5%) cytosol (25.5%) "metallodipeptidase activity (25.5%) metal ion binding (23.6%)" "IPR001160 (35%) IPR002933 (32.5%) IPR011650 (32.5%)" "Peptidase M20C, Xaa-His dipeptidase (35%) Peptidase M20 (32.5%) Peptidase M20, dimerisation domain (32.5%)" NLFAEMGYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.4 (100%) cellulase (100%) "GO:0030245 (27.7%) GO:0045493 (18.7%)" "GO:0004553 (25.8%) GO:0030246 (19.4%) GO:0016829 (6.5%)" "cellulose catabolic process (27.7%) xylan catabolic process (18.7%)" "hydrolase activity, hydrolyzing O-glycosyl compounds (25.8%) carbohydrate binding (19.4%) lyase activity (6.5%)" "IPR002037 (16.5%) IPR008928 (15.8%) IPR012341 (15.8%)" "Glycoside hydrolase, family 8 (16.5%) Six-hairpin glycosidase superfamily (15.8%) Six-hairpin glycosidase-like superfamily (15.8%)" WNQFGCFVPLYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (33.9%) "GO:0004553 (33.9%) GO:0030246 (32.2%)" carbohydrate metabolic process (33.9%) "hydrolase activity, hydrolyzing O-glycosyl compounds (33.9%) carbohydrate binding (32.2%)" "IPR000322 (11.3%) IPR025887 (11.3%) IPR033403 (11.3%)" "Glycoside hydrolase family 31, TIM barrel domain (11.3%) Glycoside hydrolase family 31, N-terminal domain (11.3%) Domain of unknown function DUF5110 (11.3%)" VSPDVKPNPEDGTVDVNWNLEQK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0071709 (48.8%) "GO:0009279 (46.3%) GO:0019867 (4.9%)" membrane assembly (48.8%) "cell outer membrane (46.3%) outer membrane (4.9%)" "IPR010827 (26.3%) IPR023707 (25%) IPR034746 (25%)" "POTRA domain, BamA/TamA-like (26.3%) Outer membrane protein assembly factor BamA (25%) POTRA domain (25%)" QQGVDYDFVQSENQK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0016020 (14.9%) "GO:0005524 (42.6%) GO:0016301 (42.6%)" membrane (14.9%) "ATP binding (42.6%) kinase activity (42.6%)" "IPR001206 (20.8%) IPR045540 (20.8%) IPR050187 (20.8%)" "Diacylglycerol kinase, catalytic domain (20.8%) YegS/DAGK, C-terminal domain (20.8%) Lipid Phosphate Formation and Regulation (20.8%)" TFFQELYAAGCR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 2.1.1.14 (100%) 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (100%) "GO:0009086 (25%) GO:0032259 (25%)" "GO:0003871 (25%) GO:0008270 (25%)" "methionine biosynthetic process (25%) methylation (25%)" "5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity (25%) zinc ion binding (25%)" "IPR002629 (51.3%) IPR038071 (48.7%)" "Cobalamin-independent methionine synthase MetE, C-terminal/archaeal (51.3%) UROD/MetE-like superfamily (48.7%)" TFQVGFK root "GO:0043043 (21.3%) GO:0006886 (7.8%) GO:0016192 (6.9%)" "GO:0005829 (21.3%) GO:0012505 (7.8%) GO:0030131 (7.8%)" "GO:0003746 (21.3%) GO:0005085 (0.6%) GO:0015280 (0.6%)" "peptide biosynthetic process (21.3%) intracellular protein transport (7.8%) vesicle-mediated transport (6.9%)" "cytosol (21.3%) endomembrane system (7.8%) clathrin adaptor complex (7.8%)" "translation elongation factor activity (21.3%) guanyl-nucleotide exchange factor activity (0.6%) ligand-gated sodium channel activity (0.6%)" "IPR001059 (8.6%) IPR008991 (8.6%) IPR011768 (8.6%)" "Translation elongation factor P/YeiP, central (8.6%) Translation protein SH3-like domain superfamily (8.6%) Translation elongation factor P (8.6%)" VMLQAGPESR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (23.8%) GO:0005886 (25.8%) "GO:0042910 (25.8%) GO:0015562 (24.5%)" response to toxic substance (23.8%) plasma membrane (25.8%) "xenobiotic transmembrane transporter activity (25.8%) efflux transmembrane transporter activity (24.5%)" "IPR001036 (34.2%) IPR027463 (33.3%) IPR004764 (32.5%)" "Acriflavin resistance protein (34.2%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.3%) Multidrug resistance protein MdtF-like (32.5%)" LRPSYFPFTEPSAEMDLSCNLCGGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.20 (100%) phenylalanine--tRNA ligase (100%) "GO:0006432 (16.6%) GO:0043039 (0.1%)" GO:0005737 (16.6%) "GO:0000049 (16.7%) GO:0004826 (16.7%) GO:0005524 (16.7%)" "phenylalanyl-tRNA aminoacylation (16.6%) tRNA aminoacylation (0.1%)" cytoplasm (16.6%) "tRNA binding (16.7%) phenylalanine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR002319 (14.6%) IPR045864 (14.6%) IPR006195 (14.5%)" "Phenylalanyl-tRNA synthetase (14.6%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (14.6%) Aminoacyl-tRNA synthetase, class II (14.5%)" LPVFNGSLECEFR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "2.1.1.- (66.7%) 2.1.1.173 (33.3%)" "Methyltransferases (66.7%) 23S rRNA (guanine(2445)-N(2))-methyltransferase (33.3%)" "GO:0008990 (33.3%) GO:0070043 (33.3%) GO:0003723 (32.6%)" "rRNA (guanine-N2-)-methyltransferase activity (33.3%) rRNA (guanine-N7-)-methyltransferase activity (33.3%) RNA binding (32.6%)" "IPR000241 (17.2%) IPR002052 (17.2%) IPR004114 (16.8%)" "Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain (17.2%) DNA methylase, N-6 adenine-specific, conserved site (17.2%) THUMP domain (16.8%)" KEETDDWWNGMNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0005975 (50%) GO:0016798 (50%) carbohydrate metabolic process (50%) hydrolase activity, acting on glycosyl bonds (50%) "IPR006047 (14.9%) IPR015171 (14.9%) IPR019492 (14.9%)" "Glycosyl hydrolase family 13, catalytic domain (14.9%) Cyclomaltodextrinase, N-terminal (14.9%) Cyclo-malto-dextrinase, C-terminal (14.9%)" QLLVQEHDAVR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (16.8%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (16.3%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (16.8%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (16.3%)" "IPR007081 (9.2%) IPR045867 (9.2%) IPR007083 (9.2%)" "RNA polymerase Rpb1, domain 5 (9.2%) DNA-directed RNA polymerase, subunit beta-prime (9.2%) RNA polymerase Rpb1, domain 4 (9.2%)" YPSSYYSR Bacteroidota Bacteria Pseudomonadati Bacteroidota GO:0044718 (33.3%) GO:0009279 (33.3%) GO:0015344 (33.3%) siderophore transmembrane transport (33.3%) cell outer membrane (33.3%) siderophore uptake transmembrane transporter activity (33.3%) "IPR008969 (16.7%) IPR012910 (16.7%) IPR036942 (16.7%)" "Carboxypeptidase-like, regulatory domain superfamily (16.7%) TonB-dependent receptor, plug domain (16.7%) TonB-dependent receptor-like, beta-barrel domain superfamily (16.7%)" LDGMSYSQLMGALHK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0006412 (17.4%) GO:0000027 (13%)" "GO:0005840 (17.4%) GO:1990904 (17.4%)" "GO:0003735 (17.4%) GO:0019843 (17.4%)" "translation (17.4%) ribosomal large subunit assembly (13%)" "ribosome (17.4%) ribonucleoprotein complex (17.4%)" "structural constituent of ribosome (17.4%) rRNA binding (17.4%)" "IPR005813 (33.3%) IPR035566 (33.3%) IPR049946 (33.3%)" "Large ribosomal subunit protein bL20 (33.3%) Ribosomal protein bL20, C-terminal (33.3%) Large ribosomal subunit protein bL20, conserved site (33.3%)" GPEAAYDYVNQVR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.6%) IPR033985 (34.6%) IPR011990 (30.8%)" "RagB/SusD domain (34.6%) SusD-like, N-terminal (34.6%) Tetratricopeptide-like helical domain superfamily (30.8%)" SDLVDLFEGVAAGDLDKR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.3.4.13 (100%) phosphoribosylamine--glycine ligase (100%) "GO:0009113 (20.2%) GO:0006189 (19.2%) GO:0006164 (1%)" "GO:0004637 (20.2%) GO:0005524 (20.2%) GO:0046872 (19.2%)" "purine nucleobase biosynthetic process (20.2%) 'de novo' IMP biosynthetic process (19.2%) purine nucleotide biosynthetic process (1%)" "phosphoribosylamine-glycine ligase activity (20.2%) ATP binding (20.2%) metal ion binding (19.2%)" "IPR000115 (11.7%) IPR020560 (11.7%) IPR011054 (11.1%)" "Phosphoribosylglycinamide synthetase (11.7%) Phosphoribosylglycinamide synthetase, C-domain (11.7%) Rudiment single hybrid motif (11.1%)" NSFLVFSGTNSR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 2.7.6.1 (100%) ribose-phosphate diphosphokinase (100%) "GO:0006015 (11.1%) GO:0006164 (11.1%) GO:0009156 (11.1%)" "GO:0002189 (11.1%) GO:0005737 (11.1%)" "GO:0000287 (11.1%) GO:0004749 (11.1%) GO:0005524 (11.1%)" "5-phosphoribose 1-diphosphate biosynthetic process (11.1%) purine nucleotide biosynthetic process (11.1%) ribonucleoside monophosphate biosynthetic process (11.1%)" "ribose phosphate diphosphokinase complex (11.1%) cytoplasm (11.1%)" "magnesium ion binding (11.1%) ribose phosphate diphosphokinase activity (11.1%) ATP binding (11.1%)" "IPR000836 (16.7%) IPR000842 (16.7%) IPR005946 (16.7%)" "Phosphoribosyltransferase domain (16.7%) Phosphoribosyl pyrophosphate synthetase, conserved site (16.7%) Ribose-phosphate pyrophosphokinase (16.7%)" EVFDFVGLK root "1.6.5.11 (53.8%) 1.6.5.9 (46.2%)" "Transferred entry: 1.6.5.9 (53.8%) NADH:ubiquinone reductase (non-electrogenic) (46.2%)" GO:0046513 (1.7%) "GO:0005886 (23.3%) GO:0005783 (1.7%) GO:0016020 (1.7%)" "GO:0008137 (23.3%) GO:0048038 (23.3%) GO:0051287 (23.3%)" ceramide biosynthetic process (1.7%) "plasma membrane (23.3%) endoplasmic reticulum (1.7%) membrane (1.7%)" "NADH dehydrogenase (ubiquinone) activity (23.3%) quinone binding (23.3%) NAD binding (23.3%)" "IPR001135 (19.4%) IPR001268 (19.4%) IPR022885 (19.4%)" "NADH-quinone oxidoreductase, subunit D (19.4%) NADH:ubiquinone oxidoreductase, 30kDa subunit (19.4%) NAD(P)H-quinone oxidoreductase subunit D/H (19.4%)" EQQLDVLAR Bacteria Bacteria 2.3.1.54 (100%) formate C-acetyltransferase (100%) GO:0006006 (32.5%) GO:0005829 (33.6%) "GO:0008861 (33.6%) GO:0016829 (0.4%)" glucose metabolic process (32.5%) cytosol (33.6%) "formate C-acetyltransferase activity (33.6%) lyase activity (0.4%)" "IPR001150 (20.2%) IPR019777 (20.2%) IPR050244 (20.2%)" "Glycine radical domain (20.2%) Formate C-acetyltransferase glycine radical, conserved site (20.2%) Autonomous Glycyl Radical Cofactor (20.2%)" LLDLLGDMALLGKPLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.5.1.108 (53.9%) 4.2.1.59 (46.1%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (53.9%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (46.1%)" "GO:0009245 (14.5%) GO:0006633 (13%)" "GO:0016020 (14.5%) GO:0005737 (14.4%)" "GO:0046872 (14.5%) GO:0103117 (14.5%) GO:0019171 (7.3%)" "lipid A biosynthetic process (14.5%) fatty acid biosynthetic process (13%)" "membrane (14.5%) cytoplasm (14.4%)" "metal ion binding (14.5%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.5%) (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity (7.3%)" "IPR004463 (14.7%) IPR013114 (14.7%) IPR011334 (14.4%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.7%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.7%) UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal (14.4%)" VGFSPSLSLGWR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.4%) IPR023996 (34.4%) IPR037066 (31.3%)" "TonB-dependent receptor, plug domain (34.4%) TonB-dependent outer membrane protein, SusC/RagA (34.4%) TonB-dependent receptor, plug domain superfamily (31.3%)" QPLQLLEAEGKYDLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) GO:0022627 (25%) "GO:0003723 (25%) GO:0003735 (25%)" translation (25%) cytosolic small ribosomal subunit (25%) "RNA binding (25%) structural constituent of ribosome (25%)" "IPR000754 (20%) IPR014721 (20%) IPR020568 (20%)" "Small ribosomal subunit protein uS9 (20%) Small ribosomal subunit protein uS5 domain 2-type fold, subgroup (20%) Ribosomal protein uS5 domain 2-type superfamily (20%)" MMGVSFDK Bacteroidota Bacteria Pseudomonadati Bacteroidota 6.1.1.19 (100%) arginine--tRNA ligase (100%) GO:0006420 (24.9%) GO:0005737 (24.9%) "GO:0004814 (24.9%) GO:0005524 (24.9%) GO:0016874 (0.3%)" arginyl-tRNA aminoacylation (24.9%) cytoplasm (24.9%) "arginine-tRNA ligase activity (24.9%) ATP binding (24.9%) ligase activity (0.3%)" "IPR001278 (12.7%) IPR001412 (12.7%) IPR008909 (12.7%)" "Arginine-tRNA ligase (12.7%) Aminoacyl-tRNA synthetase, class I, conserved site (12.7%) DALR anticodon binding (12.7%)" GEEGLHEALDELCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "1.4.1.13 (97.6%) 1.4.-.- (2.4%)" "glutamate synthase (NADPH) (97.6%) Acting on the CH-NH2 group of donors (2.4%)" "GO:0006537 (19.8%) GO:0019676 (19.8%)" "GO:0046872 (19.8%) GO:0051538 (19.8%) GO:0015930 (14.2%)" "glutamate biosynthetic process (19.8%) ammonia assimilation cycle (19.8%)" "metal ion binding (19.8%) 3 iron, 4 sulfur cluster binding (19.8%) glutamate synthase activity (14.2%)" "IPR006982 (13%) IPR002489 (12.7%) IPR002932 (12.7%)" "Glutamate synthase, central-N (13%) Glutamate synthase, alpha subunit, C-terminal (12.7%) Glutamate synthase domain (12.7%)" SAYALGGLGSGVCK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.4.16 (50.6%) 6.3.5.5 (49.4%)" "carbamoyl-phosphate synthase (ammonia) (50.6%) carbamoyl-phosphate synthase (glutamine-hydrolyzing) (49.4%)" "GO:0006541 (14.1%) GO:0006221 (13.4%) GO:0006526 (13.4%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "glutamine metabolic process (14.1%) pyrimidine nucleotide biosynthetic process (13.4%) L-arginine biosynthetic process (13.4%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.5%) IPR011761 (10.5%) IPR005483 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.5%) ATP-grasp fold (10.5%) Carbamoyl phosphate synthase, CPSase domain (10.2%)" TCLDKLNTLDDELNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0030313 (100%) cell envelope (100%) "IPR018976 (33.3%) IPR034982 (33.3%) IPR038352 (33.3%)" "Imelysin-like domain (33.3%) Iron-regulated protein A, imelysin-like domain (33.3%) Imelysin-like domain superfamily (33.3%)" ATVGSVGNSDHALEQSGK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0002181 (20%) GO:0015934 (20%) "GO:0003735 (20%) GO:0016740 (20%) GO:0019843 (20%)" cytoplasmic translation (20%) large ribosomal subunit (20%) "structural constituent of ribosome (20%) transferase activity (20%) rRNA binding (20%)" "IPR002171 (11.1%) IPR005880 (11.1%) IPR008991 (11.1%)" "Large ribosomal subunit protein uL2 (11.1%) Large ribosomal subunit protein uL2, bacteria/organella (11.1%) Translation protein SH3-like domain superfamily (11.1%)" ALNFWQNSPMK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) IPR036777 (100%) Nucleoside-specific channel-forming protein, Tsx-like superfamily (100%) YTQEEVDAFGSGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (20%) IPR023996 (20%) IPR023997 (20%)" "TonB-dependent receptor, plug domain (20%) TonB-dependent outer membrane protein, SusC/RagA (20%) TonB-dependent outer membrane protein SusC/RagA, conserved site (20%)" QLHEDFGSLDLLVNNAGLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 1.1.1.100 (100%) 3-oxoacyl-[acyl-carrier-protein] reductase (100%) GO:0006633 (33.3%) "GO:0004316 (33.3%) GO:0051287 (33.3%)" fatty acid biosynthetic process (33.3%) "3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity (33.3%) NAD binding (33.3%)" "IPR002347 (19%) IPR050259 (19%) IPR036291 (16.7%)" "Short-chain dehydrogenase/reductase SDR (19%) Short-chain dehydrogenases/reductases (19%) NAD(P)-binding domain superfamily (16.7%)" YFASASYR root GO:0030198 (2.1%) "GO:0009279 (80.9%) GO:0005576 (4.3%) GO:0005615 (2.1%)" "GO:0005509 (4.3%) GO:0016798 (2.1%)" extracellular matrix organization (2.1%) "cell outer membrane (80.9%) extracellular region (4.3%) extracellular space (2.1%)" "calcium ion binding (4.3%) hydrolase activity, acting on glycosyl bonds (2.1%)" "IPR023996 (14%) IPR023997 (14%) IPR036942 (14%)" "TonB-dependent outer membrane protein, SusC/RagA (14%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14%) TonB-dependent receptor-like, beta-barrel domain superfamily (14%)" SFMSAASFQETTK Bacteria Bacteria 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) "GO:0000428 (17%) GO:0005829 (0%)" "GO:0003899 (16.9%) GO:0003677 (16.8%) GO:0000287 (15.9%)" DNA-templated transcription (16.8%) "DNA-directed RNA polymerase complex (17%) cytosol (0%)" "DNA-directed RNA polymerase activity (16.9%) DNA binding (16.8%) magnesium ion binding (15.9%)" "IPR007081 (9.3%) IPR045867 (9.2%) IPR007083 (9.1%)" "RNA polymerase Rpb1, domain 5 (9.3%) DNA-directed RNA polymerase, subunit beta-prime (9.2%) RNA polymerase Rpb1, domain 4 (9.1%)" ATFFMVGENVLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 3.-.-.- (100%) Hydrolases (100%) "GO:0005975 (31.1%) GO:0045493 (1.6%)" GO:0016020 (32.8%) "GO:0016810 (32.8%) GO:0016798 (1.6%)" "carbohydrate metabolic process (31.1%) xylan catabolic process (1.6%)" membrane (32.8%) "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (32.8%) hydrolase activity, acting on glycosyl bonds (1.6%)" "IPR002509 (33.3%) IPR011330 (33.3%) IPR050248 (33.3%)" "NodB homology domain (33.3%) Glycoside hydrolase/deacetylase, beta/alpha-barrel (33.3%) Polysaccharide deacetylase, ArnD subfamily (33.3%)" EQAGAVYPTEQELSALVK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.24.- (100%) Metalloendopeptidases (100%) GO:0006508 (34.1%) "GO:0004222 (34.1%) GO:0046872 (31.8%)" proteolysis (34.1%) "metalloendopeptidase activity (34.1%) metal ion binding (31.8%)" "IPR001431 (20.3%) IPR007863 (20.3%) IPR011765 (20.3%)" "Peptidase M16, zinc-binding site (20.3%) Peptidase M16, C-terminal (20.3%) Peptidase M16, N-terminal (20.3%)" SLMPYGCFVELLPGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.4%) GO:0006396 (14%)" GO:0005829 (14.4%) "GO:0000175 (14.4%) GO:0003723 (14.4%) GO:0004654 (14.4%)" "mRNA catabolic process (14.4%) RNA processing (14%)" cytosol (14.4%) "3'-5'-RNA exonuclease activity (14.4%) RNA binding (14.4%) polyribonucleotide nucleotidyltransferase activity (14.4%)" "IPR003029 (8%) IPR012162 (8%) IPR001247 (7.8%)" "S1 domain (8%) Polyribonucleotide nucleotidyltransferase (8%) Exoribonuclease, phosphorolytic domain 1 (7.8%)" LLVGSKEEYER Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.6 (100%) DNA-directed RNA polymerase (100%) GO:0006351 (16.8%) GO:0000428 (17.2%) "GO:0003677 (16.8%) GO:0003899 (16.8%) GO:0000287 (15.5%)" DNA-templated transcription (16.8%) DNA-directed RNA polymerase complex (17.2%) "DNA binding (16.8%) DNA-directed RNA polymerase activity (16.8%) magnesium ion binding (15.5%)" "IPR000722 (9.1%) IPR006592 (9.1%) IPR007066 (9.1%)" "RNA polymerase, alpha subunit (9.1%) RNA polymerase, N-terminal (9.1%) RNA polymerase Rpb1, domain 3 (9.1%)" VLADFQTAYDVLPAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (33.8%) IPR033985 (33.8%) IPR011990 (32.3%)" "RagB/SusD domain (33.8%) SusD-like, N-terminal (33.8%) Tetratricopeptide-like helical domain superfamily (32.3%)" TVHSLLTAMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.2 (100%) aspartate carbamoyltransferase (100%) "GO:0006207 (16.7%) GO:0006520 (16.7%) GO:0044205 (16.7%)" GO:0005829 (16.7%) "GO:0004070 (16.7%) GO:0016597 (16.7%)" "'de novo' pyrimidine nucleobase biosynthetic process (16.7%) amino acid metabolic process (16.7%) 'de novo' UMP biosynthetic process (16.7%)" cytosol (16.7%) "aspartate carbamoyltransferase activity (16.7%) amino acid binding (16.7%)" "IPR002082 (20.1%) IPR006130 (20.1%) IPR006131 (20.1%)" "Aspartate carbamoyltransferase (20.1%) Aspartate/ornithine carbamoyltransferase (20.1%) Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.1%)" MLGQGMHGFVENK Pseudomonadati Bacteria Pseudomonadati "6.3.5.5 (95.2%) 6.3.4.16 (4.8%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (95.2%) carbamoyl-phosphate synthase (ammonia) (4.8%)" "GO:0006541 (14%) GO:0006221 (11.3%) GO:0006526 (11.2%)" "GO:0005737 (13.9%) GO:0005951 (0%)" "GO:0004088 (14%) GO:0005524 (14%) GO:0046872 (13.9%)" "glutamine metabolic process (14%) pyrimidine nucleotide biosynthetic process (11.3%) L-arginine biosynthetic process (11.2%)" "cytoplasm (13.9%) carbamoyl-phosphate synthase complex (0%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14%) ATP binding (14%) metal ion binding (13.9%)" "IPR005479 (10.1%) IPR011761 (10.1%) IPR005480 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) ATP-grasp fold (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%)" GHNGYSVFAGVGER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (22.9%) GO:0045259 (22.9%)" "GO:0005524 (22.9%) GO:0046933 (22.9%) GO:0016787 (8.2%)" "plasma membrane (22.9%) proton-transporting ATP synthase complex (22.9%)" "ATP binding (22.9%) proton-transporting ATP synthase activity, rotational mechanism (22.9%) hydrolase activity (8.2%)" "IPR000194 (10%) IPR003593 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) AAA+ ATPase domain (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" LAPTFGGLNLEDLK root "1.1.1.40 (95.8%) 2.3.1.8 (2%) 1.1.1.38 (1.7%)" "malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) (95.8%) phosphate acetyltransferase (2%) malate dehydrogenase (oxaloacetate-decarboxylating) (1.7%)" "GO:0006108 (15.2%) GO:0006096 (0%) GO:0006281 (0%)" "GO:0016020 (0.2%) GO:0000015 (0%) GO:0005737 (0%)" "GO:0051287 (18.3%) GO:0046872 (18%) GO:0016746 (15.3%)" "malate metabolic process (15.2%) glycolytic process (0%) DNA repair (0%)" "membrane (0.2%) phosphopyruvate hydratase complex (0%) cytoplasm (0%)" "NAD binding (18.3%) metal ion binding (18%) acyltransferase activity (15.3%)" "IPR012301 (9.2%) IPR051674 (9.2%) IPR012302 (9.1%)" "Malic enzyme, N-terminal domain (9.2%) Malate Decarboxylating Enzymes (9.2%) Malic enzyme, NAD-binding (9.1%)" SGGYNPVYVGPQTQR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0005980 (33.3%) "GO:0004134 (33.3%) GO:0004135 (33.3%)" glycogen catabolic process (33.3%) "4-alpha-glucanotransferase activity (33.3%) amylo-alpha-1,6-glucosidase activity (33.3%)" "IPR010401 (20.9%) IPR032790 (20.9%) IPR008928 (19.4%)" "Glycogen debranching enzyme (20.9%) Glycogen debranching enzyme, C-terminal (20.9%) Six-hairpin glycosidase superfamily (19.4%)" YPALSPDGTTLAFAYK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 3.4.21.- (100%) Serine endopeptidases (100%) GO:0006508 (33.3%) GO:0005737 (33.3%) GO:0008236 (33.3%) proteolysis (33.3%) cytoplasm (33.3%) serine-type peptidase activity (33.3%) "IPR005151 (14.3%) IPR011659 (14.3%) IPR012393 (14.3%)" "Tail specific protease (14.3%) WD40-like beta-propeller (14.3%) Tricorn protease (14.3%)" NGLHLLDLNK root GO:0006412 (33.3%) "GO:0022627 (33.3%) GO:0005840 (0.1%)" GO:0003735 (33.3%) translation (33.3%) "cytosolic small ribosomal subunit (33.3%) ribosome (0.1%)" structural constituent of ribosome (33.3%) "IPR001865 (25.1%) IPR005706 (25.1%) IPR023591 (25.1%)" "Small ribosomal subunit protein uS2 (25.1%) Small ribosomal subunit protein uS2, bacteria/mitochondria/plastid (25.1%) Small ribosomal subunit protein uS2, flavodoxin-like domain superfamily (25.1%)" DVGLDDNALVLTAR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20.2%) GO:0005737 (19.8%) "GO:0003852 (20.2%) GO:0003985 (19.8%) GO:0030145 (19.8%)" L-leucine biosynthetic process (20.2%) cytoplasm (19.8%) "2-isopropylmalate synthase activity (20.2%) acetyl-CoA C-acetyltransferase activity (19.8%) manganese ion binding (19.8%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR013709 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain (12.5%)" NLMLAPVELGK Bacteria Bacteria "3.6.3.- (50%) 3.6.3.27 (50%)" "Acting on acid anhydrides; catalyzing transmembrane movement of substances (50%) Transferred entry: 7.3.2.1 (50%)" GO:0005886 (13.4%) "GO:0005524 (29.2%) GO:0016887 (29.2%) GO:0015424 (28.2%)" plasma membrane (13.4%) "ATP binding (29.2%) ATP hydrolysis activity (29.2%) ABC-type amino acid transporter activity (28.2%)" "IPR003439 (16.9%) IPR050086 (16.9%) IPR003593 (16.6%)" "ABC transporter-like, ATP-binding domain (16.9%) Methionine import ATP-binding protein MetN-like (16.9%) AAA+ ATPase domain (16.6%)" AEVLLASNVNSYK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR002136 (33.3%) IPR013005 (33.3%) IPR023574 (33.3%)" "Large ribosomal subunit protein uL4 (33.3%) Large ribosomal subunit protein uL4-like (33.3%) Large ribosomal subunit protein uL4 domain superfamily (33.3%)" YDDPTWLK root GO:0015031 (33.3%) GO:0005886 (33.3%) GO:0022857 (33.3%) protein transport (33.3%) plasma membrane (33.3%) transmembrane transporter activity (33.3%) IPR003400 (100%) Biopolymer transport protein ExbD/TolR (100%) KDVLYLNAENAGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR019707 (52.4%) IPR036388 (47.6%)" "MJ1608-like (52.4%) Winged helix-like DNA-binding domain superfamily (47.6%)" EELGEAAFYGPK Bacteria Bacteria 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (13.5%) GO:0005737 (13.5%) "GO:0004829 (13.5%) GO:0005524 (13.5%) GO:0046872 (13.5%)" threonyl-tRNA aminoacylation (13.5%) cytoplasm (13.5%) "threonine-tRNA ligase activity (13.5%) ATP binding (13.5%) metal ion binding (13.5%)" "IPR002314 (9.6%) IPR002320 (9.6%) IPR006195 (9.6%)" "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) (9.6%) Threonine-tRNA ligase, class IIa (9.6%) Aminoacyl-tRNA synthetase, class II (9.6%)" LMTENPDVAYFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.2.1.22 (97.6%) 3.2.1.- (2.4%)" "alpha-galactosidase (97.6%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.4%)" GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (12.9%) IPR050985 (12.9%) IPR013785 (12.6%)" "Glycoside hydrolase family 36 (12.9%) Alpha-glycosidase and related enzymes (12.9%) Aldolase-type TIM barrel (12.6%)" YAEGLPGK root "2.1.2.1 (97.3%) 2.1.2.- (1.9%) 4.2.1.17 (0.3%)" "glycine hydroxymethyltransferase (97.3%) Hydroxymethyl-, formyl- and related transferases (1.9%) enoyl-CoA hydratase (0.3%)" "GO:0019264 (15.3%) GO:0035999 (15.3%) GO:0032259 (11%)" "GO:0005829 (14.8%) GO:0005737 (0.4%) GO:0005739 (0.1%)" "GO:0004372 (15.3%) GO:0030170 (15.3%) GO:0008168 (11%)" "glycine biosynthetic process from serine (15.3%) tetrahydrofolate interconversion (15.3%) methylation (11%)" "cytosol (14.8%) cytoplasm (0.4%) mitochondrion (0.1%)" "glycine hydroxymethyltransferase activity (15.3%) pyridoxal phosphate binding (15.3%) methyltransferase activity (11%)" "IPR039429 (14.4%) IPR049943 (14.4%) IPR001085 (14.3%)" "Serine hydroxymethyltransferase-like domain (14.4%) Serine hydroxymethyltransferase-like (14.4%) Serine hydroxymethyltransferase (14.3%)" DGLLHLSELDWK Bacteroidota Bacteria Pseudomonadati Bacteroidota 2.7.7.8 (100%) polyribonucleotide nucleotidyltransferase (100%) "GO:0006402 (14.3%) GO:0006396 (14.1%) GO:0006401 (0%)" "GO:0005829 (14.3%) GO:0005840 (0%) GO:1990904 (0%)" "GO:0004654 (14.4%) GO:0000175 (14.3%) GO:0003723 (14.3%)" "mRNA catabolic process (14.3%) RNA processing (14.1%) RNA catabolic process (0%)" "cytosol (14.3%) ribosome (0%) ribonucleoprotein complex (0%)" "polyribonucleotide nucleotidyltransferase activity (14.4%) 3'-5'-RNA exonuclease activity (14.3%) RNA binding (14.3%)" "IPR003029 (8%) IPR012162 (8%) IPR012340 (8%)" "S1 domain (8%) Polyribonucleotide nucleotidyltransferase (8%) Nucleic acid-binding, OB-fold (8%)" MNFVAGVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" MLDEYLVLLEEAK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 6.1.1.3 (100%) threonine--tRNA ligase (100%) GO:0006435 (16.5%) GO:0005737 (16.5%) "GO:0000049 (16.5%) GO:0004829 (16.5%) GO:0005524 (16.5%)" threonyl-tRNA aminoacylation (16.5%) cytoplasm (16.5%) "tRNA binding (16.5%) threonine-tRNA ligase activity (16.5%) ATP binding (16.5%)" "IPR012947 (7.8%) IPR018163 (7.8%) IPR045864 (7.8%)" "Threonyl/alanyl tRNA synthetase, SAD (7.8%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (7.8%) Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) (7.8%)" ALLYDGKEFYQSK Bacteria Bacteria 2.7.1.92 (100%) 5-dehydro-2-deoxygluconokinase (100%) "GO:0016301 (97.1%) GO:0047590 (2.9%)" "kinase activity (97.1%) 5-dehydro-2-deoxygluconokinase activity (2.9%)" "IPR011611 (33.3%) IPR029056 (33.3%) IPR052700 (33.3%)" "Carbohydrate kinase PfkB (33.3%) Ribokinase-like (33.3%) Carbohydrate kinase PfkB-like (33.3%)" AAVLLLSR root "2.7.8.5 (28.6%) 2.3.2.27 (16.7%) 2.7.10.1 (7.1%)" "CDP-diacylglycerol--glycerol-3-phosphate 1-phosphatidyltransferase (28.6%) RING-type E3 ubiquitin transferase (16.7%) receptor protein-tyrosine kinase (7.1%)" "GO:0006813 (3%) GO:0007155 (2.3%) GO:0061564 (2.1%)" "GO:0005886 (16.3%) GO:0016020 (11.2%) GO:0009986 (2.4%)" "GO:0022857 (4.1%) GO:0008324 (3%) GO:0005524 (2.4%)" "potassium ion transport (3%) cell adhesion (2.3%) axon development (2.1%)" "plasma membrane (16.3%) membrane (11.2%) cell surface (2.4%)" "transmembrane transporter activity (4.1%) monoatomic cation transmembrane transporter activity (3%) ATP binding (2.4%)" "IPR004680 (3.3%) IPR051679 (2.6%) IPR013783 (2.4%)" "Citrate transporter-like domain (3.3%) Divalent Anion Sodium Symporter-Related Transporters (2.6%) Immunoglobulin-like fold (2.4%)" NVQTYELLDPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.3.3.13 (100%) 2-isopropylmalate synthase (100%) GO:0009098 (20%) GO:0005737 (20%) "GO:0003852 (20%) GO:0003985 (20%) GO:0030145 (20%)" L-leucine biosynthetic process (20%) cytoplasm (20%) "2-isopropylmalate synthase activity (20%) acetyl-CoA C-acetyltransferase activity (20%) manganese ion binding (20%)" "IPR000891 (12.5%) IPR002034 (12.5%) IPR005671 (12.5%)" "Pyruvate carboxyltransferase (12.5%) Alpha-isopropylmalate/homocitrate synthase, conserved site (12.5%) 2-isopropylmalate synthase, bacterial-type (12.5%)" AGEVTAALAK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "GO:0006412 (16.8%) GO:0042254 (15.9%)" "GO:0005737 (16.4%) GO:0015935 (16.4%) GO:0005840 (0.4%)" "GO:0003735 (16.8%) GO:0019843 (16.5%) GO:0003723 (0.3%)" "translation (16.8%) ribosome biogenesis (15.9%)" "cytoplasm (16.4%) small ribosomal subunit (16.4%) ribosome (0.4%)" "structural constituent of ribosome (16.8%) rRNA binding (16.5%) RNA binding (0.3%)" "IPR000851 (14.4%) IPR005324 (14.4%) IPR013810 (14.3%)" "Small ribosomal subunit protein uS5 (14.4%) Small ribosomal subunit protein uS5, C-terminal (14.4%) Small ribosomal subunit protein uS5, N-terminal (14.3%)" ELVEKLEAAVDALNK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006412 (26.7%) "GO:0005840 (26.7%) GO:1990904 (20%)" GO:0003735 (26.7%) translation (26.7%) "ribosome (26.7%) ribonucleoprotein complex (20%)" structural constituent of ribosome (26.7%) "IPR036049 (40%) IPR001854 (30%) IPR018254 (30%)" "Large ribosomal subunit protein uL29 superfamily (40%) Large ribosomal subunit protein uL29 (30%) Large ribosomal subunit protein uL29, conserved site (30%)" ADLVQDLADLKPGLFR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.55 (100%) non-reducing end alpha-L-arabinofuranosidase (100%) GO:0046373 (50%) GO:0046556 (50%) L-arabinose metabolic process (50%) alpha-L-arabinofuranosidase activity (50%) "IPR003305 (17.1%) IPR010720 (17.1%) IPR051563 (17.1%)" "Carbohydrate-binding, CenC-like (17.1%) Alpha-L-arabinofuranosidase, C-terminal (17.1%) Glycosyl Hydrolase Family 51 (17.1%)" NHYNDMLVELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016787 (50%) GO:0030246 (50%)" "hydrolase activity (50%) carbohydrate binding (50%)" "IPR019563 (14.6%) IPR029483 (14.6%) IPR029486 (14.6%)" "Glycosyl-hydrolase 97, catalytic domain (14.6%) Glycosyl-hydrolase 97, C-terminal oligomerisation domain (14.6%) Glycosyl-hydrolase 97, N-terminal domain (14.6%)" KFESTFLGLTLPQNDSVMFGSLSGDK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 6.3.5.3 (100%) phosphoribosylformylglycinamidine synthase (100%) GO:0006189 (20%) GO:0005737 (20%) "GO:0004642 (20%) GO:0005524 (20%) GO:0046872 (20%)" 'de novo' IMP biosynthetic process (20%) cytoplasm (20%) "phosphoribosylformylglycinamidine synthase activity (20%) ATP binding (20%) metal ion binding (20%)" "IPR010073 (11.3%) IPR010918 (11.3%) IPR040707 (11.3%)" "Phosphoribosylformylglycinamidine synthase PurL (11.3%) PurM-like, C-terminal domain (11.3%) Phosphoribosylformylglycinamidine synthase, N-terminal (11.3%)" KGVDAEGHPHYLLK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" LCVYELATGK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "3.4.-.- (75%) 3.4.14.12 (25%)" "Acting on peptide bonds (peptidases) (75%) Xaa-Xaa-Pro tripeptidyl-peptidase (25%)" GO:0006508 (49.4%) "GO:0004252 (49.4%) GO:0004177 (1.1%)" proteolysis (49.4%) "serine-type endopeptidase activity (49.4%) aminopeptidase activity (1.1%)" "IPR011659 (22.2%) IPR001375 (21.7%) IPR011042 (20.7%)" "WD40-like beta-propeller (22.2%) Peptidase S9, prolyl oligopeptidase, catalytic domain (21.7%) Six-bladed beta-propeller, TolB-like (20.7%)" YMATATLR Bacteroidota Bacteria Pseudomonadati Bacteroidota "GO:0044718 (17.5%) GO:0006826 (1.3%)" GO:0009279 (63.7%) GO:0015344 (17.5%) "siderophore transmembrane transport (17.5%) iron ion transport (1.3%)" cell outer membrane (63.7%) siderophore uptake transmembrane transporter activity (17.5%) "IPR012910 (12.9%) IPR023996 (12.9%) IPR023997 (12.9%)" "TonB-dependent receptor, plug domain (12.9%) TonB-dependent outer membrane protein, SusC/RagA (12.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (12.9%)" VELLAPVR root "3.5.1.108 (46.7%) 4.2.1.59 (43.9%) 6.1.1.1 (1.9%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (46.7%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (43.9%) tyrosine--tRNA ligase (1.9%)" "GO:0009245 (11.7%) GO:0006633 (11.4%) GO:0043484 (0.7%)" "GO:0005737 (12.4%) GO:0016020 (12.1%) GO:0005634 (0.7%)" "GO:0046872 (11.7%) GO:0103117 (11.7%) GO:0019171 (5.8%)" "lipid A biosynthetic process (11.7%) fatty acid biosynthetic process (11.4%) regulation of RNA splicing (0.7%)" "cytoplasm (12.4%) membrane (12.1%) nucleus (0.7%)" "metal ion binding (11.7%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (11.7%) (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity (5.8%)" "IPR013114 (10.3%) IPR004463 (10.1%) IPR029069 (9.9%)" "Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (10.3%) UDP-3-O-acyl N-acetylglucosamine deacetylase (10.1%) HotDog domain superfamily (9.9%)" VNDNFLGR root 7.1.2.2 (100%) H(+)-transporting two-sector ATPase (100%) "GO:0005886 (18.3%) GO:0045259 (18.3%)" "GO:0005524 (18.3%) GO:0043531 (18.3%) GO:0046933 (18.3%)" "plasma membrane (18.3%) proton-transporting ATP synthase complex (18.3%)" "ATP binding (18.3%) ADP binding (18.3%) proton-transporting ATP synthase activity, rotational mechanism (18.3%)" "IPR000194 (10%) IPR000793 (10%) IPR004100 (10%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10%) ATP synthase, alpha subunit, C-terminal (10%) ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain (10%)" AAYALGGLGSGFADNEEELNK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "6.3.5.5 (97.1%) 6.3.4.16 (2.9%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (97.1%) carbamoyl-phosphate synthase (ammonia) (2.9%)" "GO:0006541 (13.8%) GO:0006221 (13.3%) GO:0006526 (13.3%)" GO:0005737 (13.8%) "GO:0004088 (13.8%) GO:0005524 (13.8%) GO:0046872 (13.8%)" "glutamine metabolic process (13.8%) pyrimidine nucleotide biosynthetic process (13.3%) L-arginine biosynthetic process (13.3%)" cytoplasm (13.8%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (13.8%) ATP binding (13.8%) metal ion binding (13.8%)" "IPR005479 (10.4%) IPR011761 (10.4%) IPR005480 (10.2%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.4%) ATP-grasp fold (10.4%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.2%)" LAYNLEK root "1.5.1.5 (24.4%) 3.5.4.9 (24.4%) 2.7.13.3 (7.3%)" "methylenetetrahydrofolate dehydrogenase (NADP(+)) (24.4%) methenyltetrahydrofolate cyclohydrolase (24.4%) histidine kinase (7.3%)" "GO:0016042 (12.4%) GO:0006355 (1.8%) GO:0006353 (1.3%)" "GO:0005829 (3%) GO:0016020 (2.8%) GO:0005737 (2.6%)" "GO:0016787 (12.5%) GO:0050661 (3.4%) GO:0004499 (3.2%)" "lipid catabolic process (12.4%) regulation of DNA-templated transcription (1.8%) DNA-templated transcription termination (1.3%)" "cytosol (3%) membrane (2.8%) cytoplasm (2.6%)" "hydrolase activity (12.5%) NADP binding (3.4%) N,N-dimethylaniline monooxygenase activity (3.2%)" "IPR002641 (8.9%) IPR016035 (8.9%) IPR036188 (2.5%)" "Patatin-like phospholipase domain (8.9%) Acyl transferase/acyl hydrolase/lysophospholipase (8.9%) FAD/NAD(P)-binding domain superfamily (2.5%)" LVSGVDLWMNTPTRPLEASGTSGEK Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia "2.4.1.1 (91.9%) 2.4.1.8 (8.1%)" "glycogen phosphorylase (91.9%) maltose phosphorylase (8.1%)" "GO:0005975 (32.9%) GO:0005978 (0.2%)" "GO:0008184 (33.1%) GO:0030170 (33.1%) GO:0050082 (0.5%)" "carbohydrate metabolic process (32.9%) glycogen biosynthetic process (0.2%)" "glycogen phosphorylase activity (33.1%) pyridoxal phosphate binding (33.1%) maltose phosphorylase activity (0.5%)" "IPR000811 (25%) IPR011834 (25%) IPR052182 (25%)" "Glycosyl transferase, family 35 (25%) Alpha-glucan phosphorylase (25%) Glycogen_Maltodextrin_Phosphorylase (25%)" AQYNYDDKYFASASYR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.3%) IPR023996 (14.3%) IPR023997 (14.3%)" "TonB-dependent receptor, plug domain (14.3%) TonB-dependent outer membrane protein, SusC/RagA (14.3%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.3%)" VPFEHLTPLFPDEK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "3.6.4.- (99.4%) 3.6.1.- (0.6%)" "Acting on ATP; involved in cellular and subcellular movement (99.4%) In phosphorus-containing anhydrides (0.6%)" GO:0006353 (14.3%) GO:0005829 (14.1%) "GO:0003723 (14.3%) GO:0004386 (14.3%) GO:0005524 (14.3%)" DNA-templated transcription termination (14.3%) cytosol (14.1%) "RNA binding (14.3%) helicase activity (14.3%) ATP binding (14.3%)" "IPR000194 (10.2%) IPR004665 (10.2%) IPR011113 (10.2%)" "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain (10.2%) Transcription termination factor Rho (10.2%) Rho termination factor, RNA-binding domain (10.2%)" LQSVGLQEQNAEKDYYLLR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.5.1.108 (50%) 4.2.1.59 (50%)" "UDP-3-O-acyl-N-acetylglucosamine deacetylase (50%) 3-hydroxyacyl-[acyl-carrier-protein] dehydratase (50%)" "GO:0006633 (14.3%) GO:0009245 (14.3%)" "GO:0005737 (14.3%) GO:0016020 (14.3%)" "GO:0046872 (14.3%) GO:0103117 (14.3%) GO:0016836 (10.7%)" "fatty acid biosynthetic process (14.3%) lipid A biosynthetic process (14.3%)" "cytoplasm (14.3%) membrane (14.3%)" "metal ion binding (14.3%) UDP-3-O-acyl-N-acetylglucosamine deacetylase activity (14.3%) hydro-lyase activity (10.7%)" "IPR004463 (14.8%) IPR010084 (14.8%) IPR013114 (14.8%)" "UDP-3-O-acyl N-acetylglucosamine deacetylase (14.8%) Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ (14.8%) Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ (14.8%)" VLPGVAALEK Pseudomonadati Bacteria Pseudomonadati 2.7.2.3 (100%) phosphoglycerate kinase (100%) "GO:0006094 (16.7%) GO:0006096 (16.7%)" GO:0005829 (16.7%) "GO:0004618 (16.7%) GO:0005524 (16.7%) GO:0043531 (16.7%)" "gluconeogenesis (16.7%) glycolytic process (16.7%)" cytosol (16.7%) "phosphoglycerate kinase activity (16.7%) ATP binding (16.7%) ADP binding (16.7%)" "IPR001576 (33.3%) IPR015824 (33.3%) IPR036043 (33.3%)" "Phosphoglycerate kinase (33.3%) Phosphoglycerate kinase, N-terminal (33.3%) Phosphoglycerate kinase superfamily (33.3%)" ALLVLTDGENHEPGAQEAAAAANKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR002035 (25%) IPR024163 (25%) IPR036465 (25%)" "von Willebrand factor, type A (25%) Aerotolerance regulator, N-terminal (25%) von Willebrand factor A-like domain superfamily (25%)" LLVVGPEENVNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006813 (33.3%) GO:0005886 (33.3%) GO:0008324 (33.3%) potassium ion transport (33.3%) plasma membrane (33.3%) monoatomic cation transmembrane transporter activity (33.3%) "IPR006037 (25.4%) IPR006512 (25.4%) IPR050144 (25.4%)" "Regulator of K+ conductance, C-terminal (25.4%) YidE/YbjL duplication (25.4%) AAE Transporter (25.4%)" AVLFAYDLHPR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.2.1.22 (100%) alpha-galactosidase (100%) GO:0016052 (49.7%) "GO:0004557 (49.7%) GO:0016798 (0.7%)" carbohydrate catabolic process (49.7%) "alpha-galactosidase activity (49.7%) hydrolase activity, acting on glycosyl bonds (0.7%)" "IPR031705 (12.6%) IPR013780 (12.5%) IPR002252 (12.3%)" "Glycosyl hydrolase family 36, C-terminal (12.6%) Glycosyl hydrolase, all-beta (12.5%) Glycoside hydrolase family 36 (12.3%)" FTLPESVTTWK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0004866 (100%) endopeptidase inhibitor activity (100%) "IPR001599 (19.6%) IPR051802 (19.6%) IPR002890 (19.2%)" "Alpha-2-macroglobulin (19.6%) Alpha-2-macroglobulin-like (19.6%) Macroglobulin domain (19.2%)" LEQTLFHQGSLWGDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.2%) IPR033985 (34.2%) IPR011990 (31.6%)" "RagB/SusD domain (34.2%) SusD-like, N-terminal (34.2%) Tetratricopeptide-like helical domain superfamily (31.6%)" AVEYFLKEEFDK Bacteroidota Bacteria Pseudomonadati Bacteroidota 4.3.2.2 (100%) adenylosuccinate lyase (100%) "GO:0006189 (24.5%) GO:0044208 (24.5%) GO:0006188 (5%)" "GO:0004018 (29.6%) GO:0070626 (15.8%) GO:0016829 (0.4%)" "'de novo' IMP biosynthetic process (24.5%) 'de novo' AMP biosynthetic process (24.5%) IMP biosynthetic process (5%)" "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity (29.6%) (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity (15.8%) lyase activity (0.4%)" "IPR022761 (12.6%) IPR047136 (12.6%) IPR008948 (12.5%)" "Fumarate lyase, N-terminal (12.6%) Adenylosuccinate lyase PurB, bacteria (12.6%) L-Aspartase-like (12.5%)" LSNEQSKEPVELK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016788 (94.6%) GO:0016787 (5.4%)" "hydrolase activity, acting on ester bonds (94.6%) hydrolase activity (5.4%)" "IPR053140 (34.5%) IPR013830 (33.6%) IPR036514 (31.8%)" "GDSL lipase Rv0518-like (34.5%) SGNH hydrolase-type esterase domain (33.6%) SGNH hydrolase superfamily (31.8%)" LDENFRENFNQAR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0009253 (20.2%) GO:0016052 (20.2%) GO:0016998 (20.2%)" GO:0016020 (19.1%) GO:0003796 (20.2%) "peptidoglycan catabolic process (20.2%) carbohydrate catabolic process (20.2%) cell wall macromolecule catabolic process (20.2%)" membrane (19.1%) lysozyme activity (20.2%) "IPR002053 (33.9%) IPR018077 (33.9%) IPR017853 (32.1%)" "Glycoside hydrolase, family 25 (33.9%) Glycoside hydrolase, family 25 subgroup (33.9%) Glycoside hydrolase superfamily (32.1%)" NLEVYYNFPK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (18%) IPR023996 (18%) IPR023997 (18%)" "TonB-dependent receptor, plug domain (18%) TonB-dependent outer membrane protein, SusC/RagA (18%) TonB-dependent outer membrane protein SusC/RagA, conserved site (18%)" LYDNTSVAELYEQAQTGTNR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012910 (14.9%) IPR023996 (14.9%) IPR023997 (14.9%)" "TonB-dependent receptor, plug domain (14.9%) TonB-dependent outer membrane protein, SusC/RagA (14.9%) TonB-dependent outer membrane protein SusC/RagA, conserved site (14.9%)" FQHPVAGTYK root IPR025964 (100%) GGGtGRT protein (100%) DTYQVTHLLDR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005886 (25%) "GO:0005525 (25%) GO:0015093 (25%) GO:0046914 (25%)" plasma membrane (25%) "GTP binding (25%) ferrous iron transmembrane transporter activity (25%) transition metal ion binding (25%)" "IPR003373 (9.1%) IPR005225 (9.1%) IPR007167 (9.1%)" "Ferrous iron transport protein B (9.1%) Small GTP-binding domain (9.1%) Ferrous iron transporter FeoA-like domain (9.1%)" KSGAFDEVLDFDELTR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "GO:0016788 (92.3%) GO:0016787 (7.7%)" "hydrolase activity, acting on ester bonds (92.3%) hydrolase activity (7.7%)" "IPR013830 (34.2%) IPR053140 (34.2%) IPR036514 (31.6%)" "SGNH hydrolase-type esterase domain (34.2%) GDSL lipase Rv0518-like (34.2%) SGNH hydrolase superfamily (31.6%)" ATFAGDGAPLVMVDGVER Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13%) IPR012910 (13%) IPR023996 (13%)" "TonB-dependent receptor-like, beta-barrel (13%) TonB-dependent receptor, plug domain (13%) TonB-dependent outer membrane protein, SusC/RagA (13%)" LPDGLPGLVR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "3.2.1.22 (97.2%) 3.2.1.- (2.8%)" "alpha-galactosidase (97.2%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (2.8%)" GO:0016052 (50%) GO:0004557 (50%) carbohydrate catabolic process (50%) alpha-galactosidase activity (50%) "IPR002252 (13%) IPR050985 (13%) IPR013785 (12.6%)" "Glycoside hydrolase family 36 (13%) Alpha-glycosidase and related enzymes (13%) Aldolase-type TIM barrel (12.6%)" GVALVDGGYENPVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006974 (56.1%) GO:0016020 (43.9%) DNA damage response (56.1%) membrane (43.9%) "IPR007497 (33.8%) IPR052022 (33.8%) IPR016907 (32.4%)" "Interleukin-1 receptor-associated kinase 1-binding protein 1/DUF541 (33.8%) 26 kDa periplasmic antigen-related (33.8%) Uncharacterised conserved protein UCP029033, periplasmic protein (32.4%)" DGLDELLAK root "5.2.1.8 (44.4%) 2.3.1.292 (11.1%) 3.2.2.29 (11.1%)" "peptidylprolyl isomerase (44.4%) (phenol)carboxyphthiodiolenone synthase (11.1%) thymine-DNA glycosylase (11.1%)" "GO:0006189 (13%) GO:0006897 (2.8%) GO:0016197 (2.8%)" "GO:0005829 (13%) GO:0005886 (3.3%) GO:0000785 (1.9%)" "GO:0003937 (13%) GO:0004643 (13%) GO:0005509 (2.8%)" "'de novo' IMP biosynthetic process (13%) endocytosis (2.8%) endosomal transport (2.8%)" "cytosol (13%) plasma membrane (3.3%) chromatin (1.9%)" "IMP cyclohydrolase activity (13%) phosphoribosylaminoimidazolecarboxamide formyltransferase activity (13%) calcium ion binding (2.8%)" "IPR002695 (13.4%) IPR011607 (13.4%) IPR036914 (13.4%)" "Bifunctional purine biosynthesis protein PurH-like (13.4%) Methylglyoxal synthase-like domain (13.4%) Methylglyoxal synthase-like domain superfamily (13.4%)" MEHALYVQQLR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (25%) "GO:0005840 (25%) GO:1990904 (25%)" GO:0003735 (25%) translation (25%) "ribosome (25%) ribonucleoprotein complex (25%)" structural constituent of ribosome (25%) "IPR001911 (50%) IPR038380 (50%)" "Small ribosomal subunit protein bS21 (50%) Small ribosomal subunit protein bS21 superfamily (50%)" KDPVSSAGHADLVEDGK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.2.1.- (100%) Glycosidases, i.e. enzymes hydrolyzing O- and S-glycosyl compounds (100%) GO:0005975 (50%) GO:0004553 (50%) carbohydrate metabolic process (50%) hydrolase activity, hydrolyzing O-glycosyl compounds (50%) "IPR006710 (20.6%) IPR051795 (20.6%) IPR041542 (20.1%)" "Glycoside hydrolase, family 43 (20.6%) Glycosyl Hydrolase Family 43 (20.6%) Beta-xylosidase, C-terminal Concanavalin A-like domain (20.1%)" NGYTLYATAGTAK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "6.3.5.5 (50.7%) 6.3.4.16 (49.3%)" "carbamoyl-phosphate synthase (glutamine-hydrolyzing) (50.7%) carbamoyl-phosphate synthase (ammonia) (49.3%)" "GO:0006221 (14.1%) GO:0006526 (14.1%) GO:0006541 (14.1%)" GO:0005737 (14.1%) "GO:0004088 (14.1%) GO:0005524 (14.1%) GO:0046872 (14.1%)" "pyrimidine nucleotide biosynthetic process (14.1%) L-arginine biosynthetic process (14.1%) glutamine metabolic process (14.1%)" cytoplasm (14.1%) "carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity (14.1%) ATP binding (14.1%) metal ion binding (14.1%)" "IPR005479 (10.1%) IPR005480 (10.1%) IPR006275 (10.1%)" "Carbamoyl phosphate synthase, ATP-binding domain (10.1%) Carbamoyl-phosphate synthetase, large subunit oligomerisation domain (10.1%) Carbamoyl-phosphate synthase, large subunit (10.1%)" YAAAQGELANAFSK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) "IPR007156 (50%) IPR023353 (50%)" "MamQ/LemA (50%) LemA-like domain superfamily (50%)" TLSSSYTESSLESFAFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" SYAFDYK root "6.3.4.14 (50%) 2.3.1.- (16.7%) 2.7.7.48 (16.7%)" "biotin carboxylase (50%) Transferring groups other than amino-acyl groups (16.7%) RNA-directed RNA polymerase (16.7%)" "GO:0006623 (9.7%) GO:0009267 (9.7%) GO:0016236 (9.7%)" "GO:0005770 (9.7%) GO:0030897 (9.7%) GO:0005576 (8.2%)" "GO:0046872 (3.5%) GO:0016491 (2.9%) GO:0004312 (0.9%)" "protein targeting to vacuole (9.7%) cellular response to starvation (9.7%) macroautophagy (9.7%)" "late endosome (9.7%) HOPS complex (9.7%) extracellular region (8.2%)" "metal ion binding (3.5%) oxidoreductase activity (2.9%) fatty acid synthase activity (0.9%)" "IPR015943 (6.3%) IPR045111 (6.3%) IPR011990 (6.1%)" "WD40/YVTN repeat-like-containing domain superfamily (6.3%) Vacuolar protein sorting-associated protein Vps41/Vps8 (6.3%) Tetratricopeptide-like helical domain superfamily (6.1%)" YASDPDVGPR Pseudomonadati Bacteria Pseudomonadati GO:0005737 (6.5%) "GO:0016747 (83.9%) GO:0008999 (6.5%) GO:0016740 (3.2%)" cytoplasm (6.5%) "acyltransferase activity, transferring groups other than amino-acyl groups (83.9%) protein-N-terminal-alanine acetyltransferase activity (6.5%) transferase activity (3.2%)" "IPR000182 (33.3%) IPR016181 (33.3%) IPR051531 (33.3%)" "GNAT domain (33.3%) Acyl-CoA N-acyltransferase (33.3%) N-acetyltransferase (33.3%)" TVGDFNQALDANHSTDLLNLSEALQEK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0005524 (50%) GO:0016301 (50%)" "ATP binding (50%) kinase activity (50%)" "IPR006083 (33.3%) IPR018163 (33.3%) IPR027417 (33.3%)" "Phosphoribulokinase/uridine kinase (33.3%) Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily (33.3%) P-loop containing nucleoside triphosphate hydrolase (33.3%)" LGLSAEDLDKR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.1.1.1 (100%) alanine racemase (100%) GO:0030632 (19.6%) "GO:0005524 (20.6%) GO:0016881 (20.6%) GO:0008784 (19.6%)" D-alanine biosynthetic process (19.6%) "ATP binding (20.6%) acid-amino acid ligase activity (20.6%) alanine racemase activity (19.6%)" "IPR051046 (10.6%) IPR001608 (10.3%) IPR013221 (10.3%)" "MurCDEF Family: Cell Wall and Coenzyme F430 Synthesis (10.6%) Alanine racemase, N-terminal (10.3%) Mur ligase, central (10.3%)" LSAEVSDGVLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella "IPR002068 (34%) IPR031107 (34%) IPR008978 (31.9%)" "Alpha crystallin/Hsp20 domain (34%) Small heat shock protein (34%) HSP20-like chaperone (31.9%)" GSHDFQLTEDKEGER Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 4.1.1.23 (100%) orotidine-5'-phosphate decarboxylase (100%) "GO:0006207 (33.3%) GO:0044205 (31.8%) GO:0009220 (1.5%)" GO:0004590 (33.3%) "'de novo' pyrimidine nucleobase biosynthetic process (33.3%) 'de novo' UMP biosynthetic process (31.8%) pyrimidine ribonucleotide biosynthetic process (1.5%)" orotidine-5'-phosphate decarboxylase activity (33.3%) "IPR001754 (25.6%) IPR011995 (25.6%) IPR011060 (24.4%)" "Orotidine 5'-phosphate decarboxylase domain (25.6%) Orotidine 5'-phosphate decarboxylase, type 2 (25.6%) Ribulose-phosphate binding barrel (24.4%)" SLLQNFDAPTVVK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009267 (50%) GO:0005886 (50%) cellular response to starvation (50%) plasma membrane (50%) "IPR003706 (50%) IPR051605 (50%)" "CstA, N-terminal domain (50%) Peptide Transporter Carbon Starvation (50%)" NPAPDVLMGLTTK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (13.2%) IPR012910 (13.2%) IPR023996 (13.2%)" "TonB-dependent receptor-like, beta-barrel (13.2%) TonB-dependent receptor, plug domain (13.2%) TonB-dependent outer membrane protein, SusC/RagA (13.2%)" LFGYPGLDLENK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales "2.7.1.- (66.7%) 2.7.1.4 (33.3%)" "Phosphotransferases with an alcohol group as acceptor (66.7%) fructokinase (33.3%)" "GO:0016301 (98.7%) GO:0008865 (1.3%)" "kinase activity (98.7%) fructokinase activity (1.3%)" "IPR011611 (27.8%) IPR050306 (27.8%) IPR029056 (26.7%)" "Carbohydrate kinase PfkB (27.8%) PfkB Carbohydrate Kinase (27.8%) Ribokinase-like (26.7%)" YGLGELKDMLTFGGSPR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "GO:0005524 (50%) GO:0016887 (50%)" "ATP binding (50%) ATP hydrolysis activity (50%)" "IPR011703 (25.4%) IPR027417 (25.4%) IPR050764 (25.4%)" "ATPase, AAA-3 (25.4%) P-loop containing nucleoside triphosphate hydrolase (25.4%) CbbQ/NirQ/NorQ/GpvN (25.4%)" LSNYFFDYLK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (33.3%) "GO:0008236 (33.3%) GO:0008239 (33.3%)" proteolysis (33.3%) "serine-type peptidase activity (33.3%) dipeptidyl-peptidase activity (33.3%)" "IPR001375 (25.3%) IPR002469 (25.3%) IPR050278 (25.3%)" "Peptidase S9, prolyl oligopeptidase, catalytic domain (25.3%) Dipeptidylpeptidase IV, N-terminal domain (25.3%) Serine protease S9B/DPPIV (25.3%)" AYLYNGQYAEALADAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GGVLMDVTTPEQAK root "4.3.3.6 (99.8%) 4.-.-.- (0.2%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolyzing) (99.8%) Lyases (0.2%)" "GO:0006520 (24.9%) GO:0008615 (24.9%) GO:0042823 (24.9%)" "GO:0036381 (24.3%) GO:0016843 (0.6%) GO:0016757 (0.2%)" "amino acid metabolic process (24.9%) pyridoxine biosynthetic process (24.9%) pyridoxal phosphate biosynthetic process (24.9%)" "pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity (24.3%) amine-lyase activity (0.6%) glycosyltransferase activity (0.2%)" "IPR001852 (25%) IPR013785 (25%) IPR033755 (25%)" "Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ (25%) Aldolase-type TIM barrel (25%) PdxS/SNZ N-terminal domain (25%)" KLEFAFEGLR root "GO:0009279 (91.7%) GO:0016020 (8.3%)" "cell outer membrane (91.7%) membrane (8.3%)" "IPR012944 (34.4%) IPR033985 (34.4%) IPR011990 (31.3%)" "RagB/SusD domain (34.4%) SusD-like, N-terminal (34.4%) Tetratricopeptide-like helical domain superfamily (31.3%)" LSMDVDSR root "2.6.1.39 (19%) 2.6.1.4 (19%) 2.6.1.63 (19%)" "2-aminoadipate transaminase (19%) glycine transaminase (19%) kynurenine--glyoxylate transaminase (19%)" "GO:0016485 (15.4%) GO:1901605 (6.1%) GO:0005975 (0.5%)" "GO:0005886 (15.4%) GO:0005759 (5.6%) GO:0005634 (0.5%)" "GO:0004222 (15.4%) GO:0046872 (15.4%) GO:0016212 (6.1%)" "protein processing (15.4%) alpha-amino acid metabolic process (6.1%) carbohydrate metabolic process (0.5%)" "plasma membrane (15.4%) mitochondrial matrix (5.6%) nucleus (0.5%)" "metalloendopeptidase activity (15.4%) metal ion binding (15.4%) kynurenine-oxoglutarate transaminase activity (6.1%)" "IPR000718 (14.4%) IPR008753 (14.4%) IPR018497 (14.4%)" "Peptidase M13 (14.4%) Peptidase M13, N-terminal domain (14.4%) Peptidase M13, C-terminal domain (14.4%)" ETGDLSVWK root 6.3.3.1 (100%) phosphoribosylformylglycinamidine cyclo-ligase (100%) "GO:0006189 (16.7%) GO:0046084 (16.7%) GO:0006164 (0%)" GO:0005829 (16.7%) "GO:0004637 (16.7%) GO:0004641 (16.7%) GO:0005524 (16.3%)" "'de novo' IMP biosynthetic process (16.7%) adenine biosynthetic process (16.7%) purine nucleotide biosynthetic process (0%)" cytosol (16.7%) "phosphoribosylamine-glycine ligase activity (16.7%) phosphoribosylformylglycinamidine cyclo-ligase activity (16.7%) ATP binding (16.3%)" "IPR004733 (20.1%) IPR016188 (20.1%) IPR036921 (20.1%)" "Phosphoribosylformylglycinamidine cyclo-ligase (20.1%) PurM-like, N-terminal domain (20.1%) PurM-like, N-terminal domain superfamily (20.1%)" YLFDRPALYTTALK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006089 (33.3%) "GO:0046872 (33.3%) GO:0051539 (32.2%) GO:0051536 (1.1%)" lactate metabolic process (33.3%) "metal ion binding (33.3%) 4 iron, 4 sulfur cluster binding (32.2%) iron-sulfur cluster binding (1.1%)" "IPR003741 (14.5%) IPR004452 (14.5%) IPR017896 (14.5%)" "LUD domain (14.5%) L-lactate oxidation iron-sulfur protein LutB/LldF (14.5%) 4Fe-4S ferredoxin-type, iron-sulphur binding domain (14.5%)" ADGLDTGLYELQLLEQKK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (25%) GO:1990281 (25%)" "GO:0015288 (25%) GO:0015562 (25%)" "cell outer membrane (25%) efflux pump complex (25%)" "porin activity (25%) efflux transmembrane transporter activity (25%)" "IPR003423 (50%) IPR051906 (50%)" "Outer membrane efflux protein (50%) Outer membrane protein TolC-like (50%)" LNEFEVMAPVGSR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 3.4.-.- (100%) Acting on peptide bonds (peptidases) (100%) GO:0006508 (50%) GO:0008233 (50%) proteolysis (50%) peptidase activity (50%) "IPR051454 (50%) IPR001539 (47.7%) IPR036237 (2.3%)" "RNA and ubiquinone modification enzymes (50%) Peptidase U32 (47.7%) Xylose isomerase-like superfamily (2.3%)" AGWDTHGLPVELGVEK root 6.1.1.5 (100%) isoleucine--tRNA ligase (100%) GO:0006428 (14.4%) GO:0005737 (14.2%) "GO:0004822 (14.4%) GO:0005524 (14.4%) GO:0002161 (14.2%)" isoleucyl-tRNA aminoacylation (14.4%) cytoplasm (14.2%) "isoleucine-tRNA ligase activity (14.4%) ATP binding (14.4%) aminoacyl-tRNA deacylase activity (14.2%)" "IPR002300 (12.1%) IPR023586 (12.1%) IPR014729 (12%)" "Aminoacyl-tRNA synthetase, class Ia (12.1%) Isoleucine-tRNA ligase, type 2 (12.1%) Rossmann-like alpha/beta/alpha sandwich fold (12%)" LCSSFLADK root "GO:0016020 (31.4%) GO:0005886 (19.6%)" "GO:0005351 (29.4%) GO:0022857 (19.6%)" "membrane (31.4%) plasma membrane (19.6%)" "carbohydrate:proton symporter activity (29.4%) transmembrane transporter activity (19.6%)" "IPR036259 (20.5%) IPR005828 (12.8%) IPR020846 (12.8%)" "MFS transporter superfamily (20.5%) Major facilitator, sugar transporter-like (12.8%) Major facilitator superfamily domain (12.8%)" VEVQANAGLNVAK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "IPR012910 (34.5%) IPR023996 (32.8%) IPR037066 (31%)" "TonB-dependent receptor, plug domain (34.5%) TonB-dependent outer membrane protein, SusC/RagA (32.8%) TonB-dependent receptor, plug domain superfamily (31%)" APVLAVADVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.5.1.72 (100%) quinolinate synthase (100%) GO:0034628 (20%) GO:0005829 (20%) "GO:0008987 (20%) GO:0046872 (20%) GO:0051539 (20%)" 'de novo' NAD+ biosynthetic process from L-aspartate (20%) cytosol (20%) "quinolinate synthetase A activity (20%) metal ion binding (20%) 4 iron, 4 sulfur cluster binding (20%)" "IPR003473 (49.2%) IPR036094 (45.9%) IPR023066 (4.9%)" "Quinolinate synthetase A (49.2%) Quinolinate synthetase A superfamily (45.9%) Quinolinate synthase A, type 2 (4.9%)" LNFYTDKDYMEETGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR011990 (33.3%) IPR012944 (33.3%) IPR033985 (33.3%)" "Tetratricopeptide-like helical domain superfamily (33.3%) RagB/SusD domain (33.3%) SusD-like, N-terminal (33.3%)" GTGALVGAALGAAVGGGAGNLLGK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri "GO:0009279 (87.5%) GO:0016020 (12.5%)" "cell outer membrane (87.5%) membrane (12.5%)" "IPR006665 (21.1%) IPR027367 (21.1%) IPR050330 (21.1%)" "OmpA-like domain (21.1%) YMGG-like Gly-zipper (21.1%) Bacterial Outer Membrane Structural/Functional (21.1%)" WTGLPVSR root "2.4.1.131 (50%) 2.7.7.87 (50%)" "GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase (50%) L-threonylcarbamoyladenylate synthase (50%)" "GO:0034605 (17.4%) GO:0042026 (13.5%) GO:0006508 (2.3%)" "GO:0005737 (11.6%) GO:0005829 (6.6%) GO:0016020 (0.1%)" "GO:0005524 (18.2%) GO:0016887 (18.2%) GO:0042802 (5.7%)" "cellular response to heat (17.4%) protein refolding (13.5%) proteolysis (2.3%)" "cytoplasm (11.6%) cytosol (6.6%) membrane (0.1%)" "ATP binding (18.2%) ATP hydrolysis activity (18.2%) identical protein binding (5.7%)" "IPR050130 (8.8%) IPR003959 (8.7%) IPR027417 (8.7%)" "ATP-dependent Clp protease/Chaperone ClpA/ClpB (8.8%) ATPase, AAA-type, core (8.7%) P-loop containing nucleoside triphosphate hydrolase (8.7%)" GENYQYLQEALDK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009251 (50%) GO:0008422 (50%) glucan catabolic process (50%) beta-glucosidase activity (50%) "IPR001764 (13%) IPR002772 (13%) IPR026891 (13%)" "Glycoside hydrolase, family 3, N-terminal (13%) Glycoside hydrolase family 3 C-terminal domain (13%) Fibronectin type III-like domain (13%)" YSALLGAGAR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0009636 (24.2%) GO:0005886 (25.5%) "GO:0042910 (25.5%) GO:0015562 (24.8%)" response to toxic substance (24.2%) plasma membrane (25.5%) "xenobiotic transmembrane transporter activity (25.5%) efflux transmembrane transporter activity (24.8%)" "IPR001036 (33.9%) IPR004764 (33.1%) IPR027463 (33.1%)" "Acriflavin resistance protein (33.9%) Multidrug resistance protein MdtF-like (33.1%) Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains (33.1%)" ETVYTYGEYMR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 3.1.1.- (100%) Carboxylic ester hydrolases (100%) "GO:0016788 (99.2%) GO:0046575 (0.8%)" "hydrolase activity, acting on ester bonds (99.2%) rhamnogalacturonan acetylesterase activity (0.8%)" "IPR036514 (26.2%) IPR037459 (26.2%) IPR013830 (25.5%)" "SGNH hydrolase superfamily (26.2%) Rhamnogalacturonan acetylesterase RhgT-like (26.2%) SGNH hydrolase-type esterase domain (25.5%)" GYEDPWR root 3.4.21.- (100%) Serine endopeptidases (100%) "GO:0006508 (31.6%) GO:0007029 (0.3%) GO:0007030 (0.3%)" "GO:0005737 (31.9%) GO:0000139 (0.3%) GO:0005789 (0.3%)" "GO:0008236 (31.2%) GO:0008233 (0.3%) GO:0016787 (0.2%)" "proteolysis (31.6%) endoplasmic reticulum organization (0.3%) Golgi organization (0.3%)" "cytoplasm (31.9%) Golgi membrane (0.3%) endoplasmic reticulum membrane (0.3%)" "serine-type peptidase activity (31.2%) peptidase activity (0.3%) hydrolase activity (0.2%)" "IPR011659 (13.5%) IPR005151 (13.2%) IPR012393 (13.2%)" "WD40-like beta-propeller (13.5%) Tail specific protease (13.2%) Tricorn protease (13.2%)" LKETNHALQLANER Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0016020 (100%) membrane (100%) IPR045957 (100%) Domain of unknown function DUF6377 (100%) LLNPGEADASTVVPEEFDLTK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri IPR043744 (100%) Domain of unknown function DUF5689 (100%) FELTLAK root "2.7.13.3 (25%) 2.1.1.320 (10.7%) 2.7.7.7 (10.7%)" "histidine kinase (25%) type II protein arginine methyltransferase (10.7%) DNA-directed DNA polymerase (10.7%)" "GO:0006538 (2.5%) GO:0006642 (1.4%) GO:0008203 (1.4%)" "GO:0005886 (4.9%) GO:0005737 (3.1%) GO:0009279 (2.7%)" "GO:0005524 (4.2%) GO:0004069 (2.5%) GO:0004352 (2.5%)" "L-glutamate catabolic process (2.5%) triglyceride mobilization (1.4%) cholesterol metabolic process (1.4%)" "plasma membrane (4.9%) cytoplasm (3.1%) cell outer membrane (2.7%)" "ATP binding (4.2%) L-aspartate:2-oxoglutarate aminotransferase activity (2.5%) glutamate dehydrogenase (NAD+) activity (2.5%)" "IPR011990 (2.9%) IPR027417 (1.8%) IPR007780 (1.7%)" "Tetratricopeptide-like helical domain superfamily (2.9%) P-loop containing nucleoside triphosphate hydrolase (1.8%) NAD-glutamate dehydrogenase, bacteria (1.7%)" LHDLMNDLHANCVK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006537 (25.9%) GO:0005829 (25.9%) "GO:0004354 (25.9%) GO:0000166 (22.2%)" glutamate biosynthetic process (25.9%) cytosol (25.9%) "glutamate dehydrogenase (NADP+) activity (25.9%) nucleotide binding (22.2%)" "IPR006095 (11.1%) IPR006096 (11.1%) IPR006097 (11.1%)" "Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal (11.1%) Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain (11.1%)" TGMEPHLGEVSYFK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0032790 (25%) "GO:0003746 (25%) GO:0003924 (25%) GO:0005525 (25%)" ribosome disassembly (25%) "translation elongation factor activity (25%) GTPase activity (25%) GTP binding (25%)" "IPR000640 (7.7%) IPR000795 (7.7%) IPR005225 (7.7%)" "Elongation factor EFG, domain V-like (7.7%) Translational (tr)-type GTP-binding domain (7.7%) Small GTP-binding domain (7.7%)" AKEVLTGAEALMR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.2.1.6 (100%) acetolactate synthase (100%) "GO:0009097 (14.4%) GO:0009099 (14.4%)" GO:0005948 (14.4%) "GO:0003984 (14.4%) GO:0030976 (14.4%) GO:0050660 (14.4%)" "isoleucine biosynthetic process (14.4%) L-valine biosynthetic process (14.4%)" acetolactate synthase complex (14.4%) "acetolactate synthase activity (14.4%) thiamine pyrophosphate binding (14.4%) flavin adenine dinucleotide binding (14.4%)" "IPR012001 (13.1%) IPR045229 (13.1%) IPR011766 (12.4%)" "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (13.1%) Thiamine pyrophosphate enzyme (13.1%) Thiamine pyrophosphate enzyme, TPP-binding (12.4%)" DCFPLALSTQR Bacteria Bacteria "GO:0006004 (28.4%) GO:0005996 (4.9%)" GO:0005737 (33.3%) "GO:0008736 (28.4%) GO:0016861 (4.9%)" "fucose metabolic process (28.4%) monosaccharide metabolic process (4.9%)" cytoplasm (33.3%) "L-fucose isomerase activity (28.4%) intramolecular oxidoreductase activity, interconverting aldoses and ketoses (4.9%)" "IPR009015 (53.2%) IPR015888 (46.8%)" "L-fucose isomerase, N-terminal/central domain superfamily (53.2%) L-fucose isomerase, C-terminal (46.8%)" GNHTLTFGTHNELYK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0044718 (33%) GO:0009279 (33%) "GO:0015344 (33%) GO:0004180 (1%)" siderophore transmembrane transport (33%) cell outer membrane (33%) "siderophore uptake transmembrane transporter activity (33%) carboxypeptidase activity (1%)" "IPR008969 (20.1%) IPR036942 (20.1%) IPR039426 (20.1%)" "Carboxypeptidase-like, regulatory domain superfamily (20.1%) TonB-dependent receptor-like, beta-barrel domain superfamily (20.1%) TonB-dependent receptor-like (20.1%)" WMMTDVLR Bacteroidia Bacteria Pseudomonadati Bacteroidota Bacteroidia 3.2.1.21 (100%) beta-glucosidase (100%) GO:0009251 (33.6%) GO:0042597 (32.8%) GO:0008422 (33.6%) glucan catabolic process (33.6%) periplasmic space (32.8%) beta-glucosidase activity (33.6%) "IPR001764 (11.4%) IPR002772 (11.4%) IPR026891 (11.4%)" "Glycoside hydrolase, family 3, N-terminal (11.4%) Glycoside hydrolase family 3 C-terminal domain (11.4%) Fibronectin type III-like domain (11.4%)" DGVAYDKFDDPELR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 6.1.1.6 (100%) lysine--tRNA ligase (100%) GO:0006430 (16.7%) GO:0005829 (16.7%) "GO:0000049 (16.7%) GO:0004824 (16.7%) GO:0005524 (16.7%)" lysyl-tRNA aminoacylation (16.7%) cytosol (16.7%) "tRNA binding (16.7%) lysine-tRNA ligase activity (16.7%) ATP binding (16.7%)" "IPR004364 (12.4%) IPR004365 (12.4%) IPR006195 (12.4%)" "Aminoacyl-tRNA synthetase, class II (D/K/N) (12.4%) OB-fold nucleic acid binding domain, AA-tRNA synthetase-type (12.4%) Aminoacyl-tRNA synthetase, class II (12.4%)" QLAEDLKQQAHK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0006412 (20%) "GO:0005840 (20%) GO:1990904 (20%)" "GO:0003735 (20%) GO:0019843 (20%)" translation (20%) "ribosome (20%) ribonucleoprotein complex (20%)" "structural constituent of ribosome (20%) rRNA binding (20%)" "IPR000244 (14.3%) IPR009027 (14.3%) IPR020069 (14.3%)" "Large ribosomal subunit protein bL9 (14.3%) Large ribosomal subunit protein bL9/RNase H1, N-terminal (14.3%) Large ribosomal subunit protein bL9, C-terminal (14.3%)" LDAGEEMPEYFK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 4.2.1.2 (100%) fumarate hydratase (100%) GO:0006099 (24.7%) "GO:0046872 (24.7%) GO:0051539 (24.7%) GO:0004333 (22.6%)" tricarboxylic acid cycle (24.7%) "metal ion binding (24.7%) 4 iron, 4 sulfur cluster binding (24.7%) fumarate hydratase activity (22.6%)" "IPR004647 (21.1%) IPR051208 (21.1%) IPR004646 (20.2%)" "Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain (21.1%) Class-I Fumarase/Tartrate Dehydratase (21.1%) Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain (20.2%)" AHLGLDYFDGSLNR Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella 5.3.1.14 (100%) L-rhamnose isomerase (100%) "GO:0019301 (20%) GO:0019324 (20%)" GO:0005737 (20%) "GO:0008740 (20%) GO:0030145 (20%)" "rhamnose catabolic process (20%) L-lyxose metabolic process (20%)" cytoplasm (20%) "L-rhamnose isomerase activity (20%) manganese ion binding (20%)" "IPR009308 (34.1%) IPR050337 (34.1%) IPR036237 (31.7%)" "Rhamnose isomerase (34.1%) L-rhamnose isomerase (34.1%) Xylose isomerase-like superfamily (31.7%)" VLDLTLR root "3.1.13.1 (12.3%) 2.7.13.3 (10.4%) 1.2.1.12 (4.2%)" "exoribonuclease II (12.3%) histidine kinase (10.4%) glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) (4.2%)" "GO:0015744 (9.4%) GO:0019062 (2.1%) GO:0075512 (2.1%)" "GO:0005886 (11.4%) GO:0016020 (4.3%) GO:0039625 (3%)" "GO:0022857 (11.4%) GO:0005198 (3%) GO:0005524 (2.8%)" "succinate transport (9.4%) virion attachment to host cell (2.1%) clathrin-dependent endocytosis of virus by host cell (2.1%)" "plasma membrane (11.4%) membrane (4.3%) viral inner capsid (3%)" "transmembrane transporter activity (11.4%) structural molecule activity (3%) ATP binding (2.8%)" "IPR010619 (8.7%) IPR024528 (8.6%) IPR050539 (7.3%)" "Threonine/serine exporter-like, N-terminal domain (8.7%) Threonine/Serine exporter, ThrE (8.6%) ThrE Dicarboxylate/Amino Acid Exporter (7.3%)" LNLPANPK root "2.4.1.25 (99%) 2.7.7.- (1%)" "4-alpha-glucanotransferase (99%) Nucleotidyltransferases (1%)" "GO:0005975 (24%) GO:0000272 (0.2%) GO:0002143 (0.2%)" "GO:0005737 (24%) GO:0016020 (0.7%) GO:0005576 (0.5%)" "GO:0004134 (23.8%) GO:2001070 (23.1%) GO:0000049 (0.2%)" "carbohydrate metabolic process (24%) polysaccharide catabolic process (0.2%) tRNA wobble position uridine thiolation (0.2%)" "cytoplasm (24%) membrane (0.7%) extracellular region (0.5%)" "4-alpha-glucanotransferase activity (23.8%) starch binding (23.1%) tRNA binding (0.2%)" "IPR003385 (19.5%) IPR017853 (19.1%) IPR002044 (18.9%)" "Glycoside hydrolase, family 77 (19.5%) Glycoside hydrolase superfamily (19.1%) Carbohydrate binding module family 20 (18.9%)" AMNLEKPDFADYMNK Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri 5.3.1.12 (100%) glucuronate isomerase (100%) "GO:0019698 (33.3%) GO:0042840 (33.3%)" GO:0008880 (33.3%) "D-galacturonate catabolic process (33.3%) D-glucuronate catabolic process (33.3%)" glucuronate isomerase activity (33.3%) "IPR003766 (52.2%) IPR032466 (47.8%)" "Uronate isomerase (52.2%) Metal-dependent hydrolase (47.8%)" LAWHEALGMGNENYR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 6.1.1.14 (100%) glycine--tRNA ligase (100%) "GO:0006426 (12.4%) GO:0015966 (12.4%)" "GO:0005737 (12.4%) GO:0070062 (12.4%) GO:1990742 (12.4%)" "GO:0004081 (12.4%) GO:0004820 (12.4%) GO:0005524 (12.4%)" "glycyl-tRNA aminoacylation (12.4%) diadenosine tetraphosphate biosynthetic process (12.4%)" "cytoplasm (12.4%) extracellular exosome (12.4%) microvesicle (12.4%)" "bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity (12.4%) glycine-tRNA ligase activity (12.4%) ATP binding (12.4%)" "IPR004154 (11.7%) IPR006195 (11.7%) IPR027031 (11.7%)" "Anticodon-binding (11.7%) Aminoacyl-tRNA synthetase, class II (11.7%) Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 (11.7%)" LNYYVSGGFYDQDGLAQNSTFR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0009279 (100%) cell outer membrane (100%) "IPR000531 (12.7%) IPR012910 (12.7%) IPR023996 (12.7%)" "TonB-dependent receptor-like, beta-barrel (12.7%) TonB-dependent receptor, plug domain (12.7%) TonB-dependent outer membrane protein, SusC/RagA (12.7%)" GLLVTDDVLESK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae 2.1.3.11 (100%) N-succinylornithine carbamoyltransferase (100%) "GO:0019240 (25%) GO:0042450 (25%)" "GO:0004585 (25%) GO:0016597 (25%)" "citrulline biosynthetic process (25%) L-arginine biosynthetic process via ornithine (25%)" "ornithine carbamoyltransferase activity (25%) amino acid binding (25%)" "IPR006131 (20.5%) IPR006132 (20.5%) IPR043696 (20.5%)" "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain (20.5%) Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding (20.5%) N-succinylornithine carbamoyltransferase ArgF'-like (20.5%)" MWLLNSSLGR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales GO:0016020 (100%) membrane (100%) "IPR034804 (50.3%) IPR011138 (49.7%)" "Fumarate reductase/succinate dehydrogenase, transmembrane subunit (50.3%) Succinate dehydrogenase cytochrome b558 subunit (49.7%)" DHYATVTFDNAPEGR Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae GO:0005987 (33.3%) GO:0005737 (33.3%) GO:0004575 (33.3%) sucrose catabolic process (33.3%) cytoplasm (33.3%) sucrose alpha-glucosidase activity (33.3%) "IPR001362 (14.3%) IPR013148 (14.3%) IPR013189 (14.3%)" "Glycoside hydrolase, family 32 (14.3%) Glycosyl hydrolase family 32, N-terminal (14.3%) Glycosyl hydrolase family 32, C-terminal (14.3%)" EMWQAGVTVR Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 1.1.1.86 (100%) ketol-acid reductoisomerase (NADP(+)) (100%) "GO:0009097 (21.5%) GO:0009099 (21.5%)" "GO:0004455 (21.5%) GO:0046872 (21.5%) GO:0016853 (13.9%)" "isoleucine biosynthetic process (21.5%) L-valine biosynthetic process (21.5%)" "ketol-acid reductoisomerase activity (21.5%) metal ion binding (21.5%) isomerase activity (13.9%)" "IPR000506 (16.7%) IPR008927 (16.7%) IPR013023 (16.7%)" "Ketol-acid reductoisomerase, C-terminal (16.7%) 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily (16.7%) Ketol-acid reductoisomerase (16.7%)" EVELAFEGFR Segatella copri Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella Segatella copri GO:0009279 (100%) cell outer membrane (100%) "IPR012944 (34.3%) IPR033985 (34.3%) IPR011990 (31.4%)" "RagB/SusD domain (34.3%) SusD-like, N-terminal (34.3%) Tetratricopeptide-like helical domain superfamily (31.4%)" LDTLVVSTQHDDFLK Bacteroidales Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales 2.5.1.6 (100%) methionine adenosyltransferase (100%) "GO:0006556 (16.7%) GO:0006730 (16.7%)" GO:0005737 (16.7%) "GO:0000287 (16.7%) GO:0004478 (16.7%) GO:0005524 (16.7%)" "S-adenosylmethionine biosynthetic process (16.7%) one-carbon metabolic process (16.7%)" cytoplasm (16.7%) "magnesium ion binding (16.7%) methionine adenosyltransferase activity (16.7%) ATP binding (16.7%)" "IPR002133 (16.7%) IPR022628 (16.7%) IPR022629 (16.7%)" "S-adenosylmethionine synthetase (16.7%) S-adenosylmethionine synthetase, N-terminal (16.7%) S-adenosylmethionine synthetase, central domain (16.7%)" SQDEVVAFLDSK Segatella Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae Segatella GO:0006265 (16.7%) "GO:0005737 (16.7%) GO:0009330 (16.7%)" "GO:0003677 (16.7%) GO:0003918 (16.7%) GO:0005524 (16.7%)" DNA topological change (16.7%) "cytoplasm (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex (16.7%)" "DNA binding (16.7%) DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (16.7%) ATP binding (16.7%)" "IPR002205 (20.7%) IPR050220 (20.7%) IPR013757 (19.6%)" "DNA topoisomerase, type IIA, domain A (20.7%) Type II DNA Topoisomerases (20.7%) DNA topoisomerase, type IIA, alpha-helical domain superfamily (19.6%)" VVSHFGQYNVEGLK Prevotellaceae Bacteria Pseudomonadati Bacteroidota Bacteroidia Bacteroidales Prevotellaceae "IPR016047 (52.9%) IPR011055 (47.1%)" "M23ase, beta-sheet core domain (52.9%) Duplicated hybrid motif (47.1%)"