Environment notes for reviewer audit

Operating system used for the submitted package: Windows 10/11 workstation.
Primary language: Python 3.10.
Core Python packages: pandas, numpy, scipy, statsmodels, pyarrow, matplotlib, openpyxl, Pillow, and PyMuPDF.
R components used in the broader analysis environment: R 4.x with data.table, optparse, yaml, metafor, coloc, TwoSampleMR, and ieugwasr.
LD-reference tools: 1000 Genomes Phase 3 reference files and PLINK 1.9 where genotype extraction was required.
Randomness: no stochastic model fitting was used for the submitted figures; deterministic table sorting and fixed thresholds were used.
Key colocalisation parameter: Wakefield ABF prior variance 0.15² (0.0225) for both eQTL and outcome effects, with p1 = 0.0001, p2 = 0.0001, and p12 = 0.00001.
Resource restrictions: third-party public GWAS, GTEx, MetaBrain, GEO, and 1000 Genomes resources remain subject to the original resource terms listed in Supplementary Table S1.
Executable-script availability: executable R and Python scripts are not included in the submission package; they are archived by the corresponding author and available on reasonable request under original resource-use terms.
